id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-329750-purunxce	Waldman, Amy	Childhood multiple sclerosis: A review	2006-06-28		.txt	text/plain	8430	481	49	Although children and adults with MS have similar neurological symptoms, laboratory (cerebrospinal fluid) data, and neuroimaging findings, the clinical course, pathogenesis, and treatment of childhood onset MS require further investigation. The study concluded that children and adults with MS have similar clinical profiles, including mode of onset, symptoms, and physical and laboratory (cerebral spinal fluid [CSF]) findings. The results from the Natalizumab Safety and Efficacy in Relapsing Remitting Multiple Sclerosis (AFFIRM) and Safety and Efficacy of Natalizumab in Combination with Interferon ␤-1a in Patients with Relapsing Remitting Multiple Sclerosis (SENTINEL) studies in adult patients indicate that the annualized rate of clinical relapses was reduced by 68%, the number of new and enhancing MRI lesions was reduced by 83%, and a decrease occurred in progression and prolongation of the interval before neurological deterioration, demonstrating the usefulness of the drug [Polman et al., 2006; Rudicket al., 2006] .	./cache/cord-329750-purunxce.txt	./txt/cord-329750-purunxce.txt