id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-009606-xz23twqx	Vorobieva S. Jensen, V.	Epidemiological and molecular characterization of Streptococcus pneumoniae carriage strains in pre-school children in Arkhangelsk, northern European Russia, prior to the introduction of conjugate pneumococcal vaccines	2020-04-15		.txt	text/plain	6157	311	42	title: Epidemiological and molecular characterization of Streptococcus pneumoniae carriage strains in pre-school children in Arkhangelsk, northern European Russia, prior to the introduction of conjugate pneumococcal vaccines The objective was to determine the prevalence of carriage, serotype distribution, antimicrobial susceptibility and the molecular structure of Streptococcus pneumoniae strains before marketing and introduction of PCV-13. High rates of non-susceptibility to penicillin, macrolides and multidrug resistance were associated with specific vaccine serotypes, pandemic clones, and local sequence types. pneumoniae carriage isolates in pre-school children of the Arkhangelsk region between separately located DCCs. The serotype distribution was diverse in the area, but globally reported epidemiological features, such as age-dependence, Carriage rates A 38.4% overall frequency of pneumococcal carriage rate was found in non-vaccinated pre-school children. Serotypes, antimicrobial susceptibility, and molecular epidemiology of invasive and non-invasive Streptococcus pneumoniae isolates in paediatric patients after the introduction of 13-valent conjugate vaccine in a nationwide surveillance study conducted in	./cache/cord-009606-xz23twqx.txt	./txt/cord-009606-xz23twqx.txt