id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-336743-udokbcki	Lilitsis, Emmanouil	Inspiratory effort and breathing pattern change in response to varying the assist level: a physiological study	2020-06-10		.txt	text/plain	3436	165	46	Setting the level of ventilator assist in everyday practice relies mostly on the clinical estimation of inspiratory effort, as indicated by the breathing pattern -tidal volume (VT) and respiratory rate (RR)-and clinical signs of respiratory distress (Boles et al., 2007; Hansen-Flaschen, 2000; Hess, 2001; Ray et al., 2006) . The aim of this study was to 1) characterize the responses of respiratory drive, respiratory effort, and breathing pattern to changing levels of ventilatory assist in critically ill patients and 2) assess if changes in respiratory rate may indicate changes in respiratory drive and effort. To this end, during proportional assist ventilation with adjustable gain factors (PAV+), noninvasive measurements of respiratory drive, effort (as indicated by inspiratory muscle pressure) were obtained at different levels of assist, using a validated prototype monitor (PVI) (Kondili et al., 2010; Younes et al., 2007) .	./cache/cord-336743-udokbcki.txt	./txt/cord-336743-udokbcki.txt