id sid tid token lemma pos cord-354133-11b0d499 1 1 key key NN cord-354133-11b0d499 1 2 : : : cord-354133-11b0d499 2 1 cord-354133 cord-354133 NNP cord-354133-11b0d499 2 2 - - HYPH cord-354133-11b0d499 2 3 11b0d499 11b0d499 CD cord-354133-11b0d499 2 4 authors author NNS cord-354133-11b0d499 2 5 : : : cord-354133-11b0d499 2 6 Thomas Thomas NNP cord-354133-11b0d499 2 7 , , , cord-354133-11b0d499 2 8 B. B. NNP cord-354133-11b0d499 2 9 S. S. NNP cord-354133-11b0d499 2 10 ; ; : cord-354133-11b0d499 2 11 Marks Marks NNP cord-354133-11b0d499 2 12 , , , cord-354133-11b0d499 2 13 N. N. NNP cord-354133-11b0d499 2 14 A. a. NN cord-354133-11b0d499 2 15 title title NN cord-354133-11b0d499 2 16 : : : cord-354133-11b0d499 2 17 Estimating estimate VBG cord-354133-11b0d499 2 18 the the DT cord-354133-11b0d499 2 19 Case Case NNP cord-354133-11b0d499 2 20 Fatality Fatality NNP cord-354133-11b0d499 2 21 Ratio Ratio NNP cord-354133-11b0d499 2 22 for for IN cord-354133-11b0d499 2 23 COVID-19 COVID-19 NNP cord-354133-11b0d499 2 24 using use VBG cord-354133-11b0d499 2 25 a a DT cord-354133-11b0d499 2 26 Time Time NNP cord-354133-11b0d499 2 27 - - HYPH cord-354133-11b0d499 2 28 Shifted Shifted NNP cord-354133-11b0d499 2 29 Distribution Distribution NNP cord-354133-11b0d499 2 30 Analysis Analysis NNP cord-354133-11b0d499 2 31 date date NN cord-354133-11b0d499 2 32 : : : cord-354133-11b0d499 2 33 2020 2020 CD cord-354133-11b0d499 2 34 - - SYM cord-354133-11b0d499 2 35 10 10 CD cord-354133-11b0d499 2 36 - - SYM cord-354133-11b0d499 2 37 27 27 CD cord-354133-11b0d499 2 38 journal journal NN cord-354133-11b0d499 2 39 : : : cord-354133-11b0d499 2 40 nan nan NNP cord-354133-11b0d499 3 1 DOI DOI NNP cord-354133-11b0d499 3 2 : : : cord-354133-11b0d499 3 3 10.1101/2020.10.25.20216671 10.1101/2020.10.25.20216671 CD cord-354133-11b0d499 3 4 sha sha NNP cord-354133-11b0d499 3 5 : : : cord-354133-11b0d499 4 1 971634bdbdd718221e46de27e3a1edce17f5648b 971634bdbdd718221e46de27e3a1edce17f5648b CD cord-354133-11b0d499 4 2 doc_id doc_id CD cord-354133-11b0d499 4 3 : : : cord-354133-11b0d499 4 4 354133 354133 CD cord-354133-11b0d499 4 5 cord_uid cord_uid NNS cord-354133-11b0d499 4 6 : : : cord-354133-11b0d499 4 7 11b0d499 11b0d499 CD cord-354133-11b0d499 5 1 Estimating estimate VBG cord-354133-11b0d499 5 2 the the DT cord-354133-11b0d499 5 3 case case NN cord-354133-11b0d499 5 4 fatality fatality NN cord-354133-11b0d499 5 5 ratio ratio NN cord-354133-11b0d499 5 6 ( ( -LRB- cord-354133-11b0d499 5 7 CFR CFR NNP cord-354133-11b0d499 5 8 ) ) -RRB- cord-354133-11b0d499 5 9 for for IN cord-354133-11b0d499 5 10 COVID-19 COVID-19 NNP cord-354133-11b0d499 5 11 is be VBZ cord-354133-11b0d499 5 12 an an DT cord-354133-11b0d499 5 13 important important JJ cord-354133-11b0d499 5 14 aspect aspect NN cord-354133-11b0d499 5 15 of of IN cord-354133-11b0d499 5 16 public public JJ cord-354133-11b0d499 5 17 health health NN cord-354133-11b0d499 5 18 . . . cord-354133-11b0d499 6 1 However however RB cord-354133-11b0d499 6 2 , , , cord-354133-11b0d499 6 3 calculating calculate VBG cord-354133-11b0d499 6 4 CFR CFR NNP cord-354133-11b0d499 6 5 accurately accurately RB cord-354133-11b0d499 6 6 is be VBZ cord-354133-11b0d499 6 7 problematic problematic JJ cord-354133-11b0d499 6 8 early early RB cord-354133-11b0d499 6 9 in in IN cord-354133-11b0d499 6 10 a a DT cord-354133-11b0d499 6 11 novel novel JJ cord-354133-11b0d499 6 12 disease disease NN cord-354133-11b0d499 6 13 outbreak outbreak NN cord-354133-11b0d499 6 14 , , , cord-354133-11b0d499 6 15 due due IN cord-354133-11b0d499 6 16 to to IN cord-354133-11b0d499 6 17 uncertainties uncertainty NNS cord-354133-11b0d499 6 18 regarding regard VBG cord-354133-11b0d499 6 19 the the DT cord-354133-11b0d499 6 20 time time NN cord-354133-11b0d499 6 21 course course NN cord-354133-11b0d499 6 22 of of IN cord-354133-11b0d499 6 23 disease disease NN cord-354133-11b0d499 6 24 and and CC cord-354133-11b0d499 6 25 difficulties difficulty NNS cord-354133-11b0d499 6 26 in in IN cord-354133-11b0d499 6 27 diagnosis diagnosis NN cord-354133-11b0d499 6 28 and and CC cord-354133-11b0d499 6 29 reporting reporting NN cord-354133-11b0d499 6 30 of of IN cord-354133-11b0d499 6 31 cases case NNS cord-354133-11b0d499 6 32 . . . cord-354133-11b0d499 7 1 In in IN cord-354133-11b0d499 7 2 this this DT cord-354133-11b0d499 7 3 work work NN cord-354133-11b0d499 7 4 , , , cord-354133-11b0d499 7 5 we -PRON- PRP cord-354133-11b0d499 7 6 present present VBP cord-354133-11b0d499 7 7 a a DT cord-354133-11b0d499 7 8 simple simple JJ cord-354133-11b0d499 7 9 method method NN cord-354133-11b0d499 7 10 for for IN cord-354133-11b0d499 7 11 calculating calculate VBG cord-354133-11b0d499 7 12 the the DT cord-354133-11b0d499 7 13 case case NN cord-354133-11b0d499 7 14 fatality fatality NN cord-354133-11b0d499 7 15 ratio ratio NN cord-354133-11b0d499 7 16 using use VBG cord-354133-11b0d499 7 17 only only RB cord-354133-11b0d499 7 18 public public JJ cord-354133-11b0d499 7 19 case case NN cord-354133-11b0d499 7 20 and and CC cord-354133-11b0d499 7 21 death death NN cord-354133-11b0d499 7 22 data datum NNS cord-354133-11b0d499 7 23 over over IN cord-354133-11b0d499 7 24 time time NN cord-354133-11b0d499 7 25 by by IN cord-354133-11b0d499 7 26 exploiting exploit VBG cord-354133-11b0d499 7 27 the the DT cord-354133-11b0d499 7 28 correspondence correspondence NN cord-354133-11b0d499 7 29 between between IN cord-354133-11b0d499 7 30 the the DT cord-354133-11b0d499 7 31 time time NN cord-354133-11b0d499 7 32 distributions distribution NNS cord-354133-11b0d499 7 33 of of IN cord-354133-11b0d499 7 34 cases case NNS cord-354133-11b0d499 7 35 and and CC cord-354133-11b0d499 7 36 deaths death NNS cord-354133-11b0d499 7 37 . . . cord-354133-11b0d499 8 1 The the DT cord-354133-11b0d499 8 2 time time NN cord-354133-11b0d499 8 3 - - HYPH cord-354133-11b0d499 8 4 shifted shift VBN cord-354133-11b0d499 8 5 distribution distribution NN cord-354133-11b0d499 8 6 ( ( -LRB- cord-354133-11b0d499 8 7 TSD TSD NNP cord-354133-11b0d499 8 8 ) ) -RRB- cord-354133-11b0d499 8 9 analysis analysis NN cord-354133-11b0d499 8 10 generates generate VBZ cord-354133-11b0d499 8 11 two two CD cord-354133-11b0d499 8 12 parameters parameter NNS cord-354133-11b0d499 8 13 of of IN cord-354133-11b0d499 8 14 interest interest NN cord-354133-11b0d499 8 15 : : : cord-354133-11b0d499 8 16 the the DT cord-354133-11b0d499 8 17 delay delay NN cord-354133-11b0d499 8 18 time time NN cord-354133-11b0d499 8 19 between between IN cord-354133-11b0d499 8 20 reporting reporting NN cord-354133-11b0d499 8 21 of of IN cord-354133-11b0d499 8 22 cases case NNS cord-354133-11b0d499 8 23 and and CC cord-354133-11b0d499 8 24 deaths death NNS cord-354133-11b0d499 8 25 and and CC cord-354133-11b0d499 8 26 the the DT cord-354133-11b0d499 8 27 case case NN cord-354133-11b0d499 8 28 fatality fatality NN cord-354133-11b0d499 8 29 ratio ratio NN cord-354133-11b0d499 8 30 . . . cord-354133-11b0d499 9 1 These these DT cord-354133-11b0d499 9 2 parameters parameter NNS cord-354133-11b0d499 9 3 converge converge VBP cord-354133-11b0d499 9 4 reliably reliably RB cord-354133-11b0d499 9 5 over over IN cord-354133-11b0d499 9 6 time time NN cord-354133-11b0d499 9 7 once once IN cord-354133-11b0d499 9 8 the the DT cord-354133-11b0d499 9 9 exponential exponential JJ cord-354133-11b0d499 9 10 growth growth NN cord-354133-11b0d499 9 11 phase phase NN cord-354133-11b0d499 9 12 has have VBZ cord-354133-11b0d499 9 13 finished finish VBN cord-354133-11b0d499 9 14 . . . cord-354133-11b0d499 10 1 Analysis analysis NN cord-354133-11b0d499 10 2 is be VBZ cord-354133-11b0d499 10 3 performed perform VBN cord-354133-11b0d499 10 4 for for IN cord-354133-11b0d499 10 5 early early JJ cord-354133-11b0d499 10 6 COVID covid JJ cord-354133-11b0d499 10 7 19 19 CD cord-354133-11b0d499 10 8 outbreaks outbreak NNS cord-354133-11b0d499 10 9 in in IN cord-354133-11b0d499 10 10 many many JJ cord-354133-11b0d499 10 11 countries country NNS cord-354133-11b0d499 10 12 , , , cord-354133-11b0d499 10 13 and and CC cord-354133-11b0d499 10 14 we -PRON- PRP cord-354133-11b0d499 10 15 discuss discuss VBP cord-354133-11b0d499 10 16 corrections correction NNS cord-354133-11b0d499 10 17 to to IN cord-354133-11b0d499 10 18 CFR CFR NNP cord-354133-11b0d499 10 19 values value NNS cord-354133-11b0d499 10 20 using use VBG cord-354133-11b0d499 10 21 excess excess JJ cord-354133-11b0d499 10 22 - - HYPH cord-354133-11b0d499 10 23 death death NN cord-354133-11b0d499 10 24 and and CC cord-354133-11b0d499 10 25 seroprevalence seroprevalence NN cord-354133-11b0d499 10 26 data datum NNS cord-354133-11b0d499 10 27 to to TO cord-354133-11b0d499 10 28 estimate estimate VB cord-354133-11b0d499 10 29 the the DT cord-354133-11b0d499 10 30 infection infection NN cord-354133-11b0d499 10 31 fatality fatality NN cord-354133-11b0d499 10 32 ratio ratio NN cord-354133-11b0d499 10 33 ( ( -LRB- cord-354133-11b0d499 10 34 IFR IFR NNP cord-354133-11b0d499 10 35 ) ) -RRB- cord-354133-11b0d499 10 36 . . . cord-354133-11b0d499 11 1 While while IN cord-354133-11b0d499 11 2 CFR CFR NNP cord-354133-11b0d499 11 3 values value NNS cord-354133-11b0d499 11 4 range range VBP cord-354133-11b0d499 11 5 from from IN cord-354133-11b0d499 11 6 0.2 0.2 CD cord-354133-11b0d499 11 7 - - SYM cord-354133-11b0d499 11 8 20 20 CD cord-354133-11b0d499 11 9 % % NN cord-354133-11b0d499 11 10 in in IN cord-354133-11b0d499 11 11 different different JJ cord-354133-11b0d499 11 12 countries country NNS cord-354133-11b0d499 11 13 , , , cord-354133-11b0d499 11 14 estimates estimate NNS cord-354133-11b0d499 11 15 for for IN cord-354133-11b0d499 11 16 IFR IFR NNP cord-354133-11b0d499 11 17 are be VBP cord-354133-11b0d499 11 18 mostly mostly RB cord-354133-11b0d499 11 19 around around IN cord-354133-11b0d499 11 20 0.5 0.5 CD cord-354133-11b0d499 11 21 - - HYPH cord-354133-11b0d499 11 22 0.8 0.8 CD cord-354133-11b0d499 11 23 % % NN cord-354133-11b0d499 11 24 for for IN cord-354133-11b0d499 11 25 countries country NNS cord-354133-11b0d499 11 26 that that WDT cord-354133-11b0d499 11 27 experienced experience VBD cord-354133-11b0d499 11 28 moderate moderate JJ cord-354133-11b0d499 11 29 outbreaks outbreak NNS cord-354133-11b0d499 11 30 and and CC cord-354133-11b0d499 11 31 1 1 CD cord-354133-11b0d499 11 32 - - SYM cord-354133-11b0d499 11 33 3 3 CD cord-354133-11b0d499 11 34 % % NN cord-354133-11b0d499 11 35 for for IN cord-354133-11b0d499 11 36 severe severe JJ cord-354133-11b0d499 11 37 outbreaks outbreak NNS cord-354133-11b0d499 11 38 . . . cord-354133-11b0d499 12 1 The the DT cord-354133-11b0d499 12 2 simplicity simplicity NN cord-354133-11b0d499 12 3 and and CC cord-354133-11b0d499 12 4 transparency transparency NN cord-354133-11b0d499 12 5 of of IN cord-354133-11b0d499 12 6 TSD TSD NNP cord-354133-11b0d499 12 7 analysis analysis NN cord-354133-11b0d499 12 8 enhance enhance VBP cord-354133-11b0d499 12 9 its -PRON- PRP$ cord-354133-11b0d499 12 10 usefulness usefulness NN cord-354133-11b0d499 12 11 in in IN cord-354133-11b0d499 12 12 characterizing characterize VBG cord-354133-11b0d499 12 13 a a DT cord-354133-11b0d499 12 14 new new JJ cord-354133-11b0d499 12 15 disease disease NN cord-354133-11b0d499 12 16 as as RB cord-354133-11b0d499 12 17 well well RB cord-354133-11b0d499 12 18 as as IN cord-354133-11b0d499 12 19 the the DT cord-354133-11b0d499 12 20 state state NN cord-354133-11b0d499 12 21 of of IN cord-354133-11b0d499 12 22 the the DT cord-354133-11b0d499 12 23 health health NN cord-354133-11b0d499 12 24 and and CC cord-354133-11b0d499 12 25 reporting reporting NN cord-354133-11b0d499 12 26 systems system NNS cord-354133-11b0d499 12 27 . . . cord-354133-11b0d499 13 1 The the DT cord-354133-11b0d499 13 2 novel novel JJ cord-354133-11b0d499 13 3 coronavirus coronavirus NN cord-354133-11b0d499 13 4 SARS SARS NNP cord-354133-11b0d499 13 5 - - HYPH cord-354133-11b0d499 13 6 CoV-2 CoV-2 NNP cord-354133-11b0d499 13 7 , , , cord-354133-11b0d499 13 8 and and CC cord-354133-11b0d499 13 9 its -PRON- PRP$ cord-354133-11b0d499 13 10 attendant attendant NN cord-354133-11b0d499 13 11 disease disease NN cord-354133-11b0d499 13 12 , , , cord-354133-11b0d499 13 13 COVID-19 COVID-19 NNP cord-354133-11b0d499 13 14 , , , cord-354133-11b0d499 13 15 first first RB cord-354133-11b0d499 13 16 appeared appear VBD cord-354133-11b0d499 13 17 in in IN cord-354133-11b0d499 13 18 late late JJ cord-354133-11b0d499 13 19 2019 2019 CD cord-354133-11b0d499 13 20 in in IN cord-354133-11b0d499 13 21 Wuhan Wuhan NNP cord-354133-11b0d499 13 22 , , , cord-354133-11b0d499 13 23 China China NNP cord-354133-11b0d499 13 24 . . . cord-354133-11b0d499 14 1 Since since IN cord-354133-11b0d499 14 2 then then RB cord-354133-11b0d499 14 3 , , , cord-354133-11b0d499 14 4 studies study NNS cord-354133-11b0d499 14 5 and and CC cord-354133-11b0d499 14 6 estimates estimate NNS cord-354133-11b0d499 14 7 of of IN cord-354133-11b0d499 14 8 the the DT cord-354133-11b0d499 14 9 transmissibility transmissibility NN cord-354133-11b0d499 14 10 and and CC cord-354133-11b0d499 14 11 virulence virulence NN cord-354133-11b0d499 14 12 of of IN cord-354133-11b0d499 14 13 COVID-19 covid-19 CD cord-354133-11b0d499 14 14 have have VBP cord-354133-11b0d499 14 15 abounded abound VBN cord-354133-11b0d499 14 16 , , , cord-354133-11b0d499 14 17 with with IN cord-354133-11b0d499 14 18 widely widely RB cord-354133-11b0d499 14 19 varying vary VBG cord-354133-11b0d499 14 20 results result NNS cord-354133-11b0d499 14 21 [ [ -LRB- cord-354133-11b0d499 14 22 1 1 CD cord-354133-11b0d499 14 23 ] ] -RRB- cord-354133-11b0d499 14 24 [ [ -LRB- cord-354133-11b0d499 14 25 2 2 CD cord-354133-11b0d499 14 26 ] ] -RRB- cord-354133-11b0d499 14 27 [ [ -LRB- cord-354133-11b0d499 14 28 3 3 CD cord-354133-11b0d499 14 29 ] ] -RRB- cord-354133-11b0d499 14 30 [ [ -LRB- cord-354133-11b0d499 14 31 4 4 CD cord-354133-11b0d499 14 32 ] ] -RRB- cord-354133-11b0d499 14 33 [ [ -LRB- cord-354133-11b0d499 14 34 5 5 CD cord-354133-11b0d499 14 35 ] ] -RRB- cord-354133-11b0d499 14 36 [ [ -LRB- cord-354133-11b0d499 14 37 6 6 CD cord-354133-11b0d499 14 38 ] ] -RRB- cord-354133-11b0d499 14 39 . . . cord-354133-11b0d499 15 1 Virulence virulence NN cord-354133-11b0d499 15 2 is be VBZ cord-354133-11b0d499 15 3 often often RB cord-354133-11b0d499 15 4 measured measure VBN cord-354133-11b0d499 15 5 using use VBG cord-354133-11b0d499 15 6 the the DT cord-354133-11b0d499 15 7 case case NN cord-354133-11b0d499 15 8 fatality fatality NN cord-354133-11b0d499 15 9 ratio ratio NN cord-354133-11b0d499 15 10 ( ( -LRB- cord-354133-11b0d499 15 11 also also RB cord-354133-11b0d499 15 12 called call VBN cord-354133-11b0d499 15 13 case case NN cord-354133-11b0d499 15 14 fatality fatality NN cord-354133-11b0d499 15 15 rate rate NN cord-354133-11b0d499 15 16 or or CC cord-354133-11b0d499 15 17 case case NN cord-354133-11b0d499 15 18 fatality fatality NN cord-354133-11b0d499 15 19 risk risk NN cord-354133-11b0d499 15 20 , , , cord-354133-11b0d499 15 21 CFR CFR NNP cord-354133-11b0d499 15 22 ) ) -RRB- cord-354133-11b0d499 15 23 , , , cord-354133-11b0d499 15 24 which which WDT cord-354133-11b0d499 15 25 is be VBZ cord-354133-11b0d499 15 26 the the DT cord-354133-11b0d499 15 27 number number NN cord-354133-11b0d499 15 28 of of IN cord-354133-11b0d499 15 29 deaths death NNS cord-354133-11b0d499 15 30 due due JJ cord-354133-11b0d499 15 31 to to IN cord-354133-11b0d499 15 32 a a DT cord-354133-11b0d499 15 33 disease disease NN cord-354133-11b0d499 15 34 as as IN cord-354133-11b0d499 15 35 a a DT cord-354133-11b0d499 15 36 proportion proportion NN cord-354133-11b0d499 15 37 of of IN cord-354133-11b0d499 15 38 the the DT cord-354133-11b0d499 15 39 number number NN cord-354133-11b0d499 15 40 of of IN cord-354133-11b0d499 15 41 people people NNS cord-354133-11b0d499 15 42 diagnosed diagnose VBN cord-354133-11b0d499 15 43 with with IN cord-354133-11b0d499 15 44 the the DT cord-354133-11b0d499 15 45 disease disease NN cord-354133-11b0d499 15 46 . . . cord-354133-11b0d499 16 1 The the DT cord-354133-11b0d499 16 2 CFR CFR NNP cord-354133-11b0d499 16 3 is be VBZ cord-354133-11b0d499 16 4 dependent dependent JJ cord-354133-11b0d499 16 5 on on IN cord-354133-11b0d499 16 6 the the DT cord-354133-11b0d499 16 7 particular particular JJ cord-354133-11b0d499 16 8 pathogen pathogen NN cord-354133-11b0d499 16 9 ( ( -LRB- cord-354133-11b0d499 16 10 and and CC cord-354133-11b0d499 16 11 its -PRON- PRP$ cord-354133-11b0d499 16 12 mechanism mechanism NN cord-354133-11b0d499 16 13 of of IN cord-354133-11b0d499 16 14 action action NN cord-354133-11b0d499 16 15 ) ) -RRB- cord-354133-11b0d499 16 16 and and CC cord-354133-11b0d499 16 17 the the DT cord-354133-11b0d499 16 18 immune immune JJ cord-354133-11b0d499 16 19 response response NN cord-354133-11b0d499 16 20 of of IN cord-354133-11b0d499 16 21 the the DT cord-354133-11b0d499 16 22 host host NN cord-354133-11b0d499 16 23 , , , cord-354133-11b0d499 16 24 which which WDT cord-354133-11b0d499 16 25 can can MD cord-354133-11b0d499 16 26 depend depend VB cord-354133-11b0d499 16 27 on on IN cord-354133-11b0d499 16 28 age age NN cord-354133-11b0d499 16 29 , , , cord-354133-11b0d499 16 30 sex sex NN cord-354133-11b0d499 16 31 , , , cord-354133-11b0d499 16 32 genetic genetic JJ cord-354133-11b0d499 16 33 factors factor NNS cord-354133-11b0d499 16 34 and and CC cord-354133-11b0d499 16 35 pre pre JJ cord-354133-11b0d499 16 36 - - JJ cord-354133-11b0d499 16 37 existing existing JJ cord-354133-11b0d499 16 38 medical medical JJ cord-354133-11b0d499 16 39 conditions condition NNS cord-354133-11b0d499 16 40 . . . cord-354133-11b0d499 17 1 Environmental environmental JJ cord-354133-11b0d499 17 2 factors factor NNS cord-354133-11b0d499 17 3 such such JJ cord-354133-11b0d499 17 4 as as IN cord-354133-11b0d499 17 5 climate climate NN cord-354133-11b0d499 17 6 and and CC cord-354133-11b0d499 17 7 health health NN cord-354133-11b0d499 17 8 system system NN cord-354133-11b0d499 17 9 may may MD cord-354133-11b0d499 17 10 also also RB cord-354133-11b0d499 17 11 affect affect VB cord-354133-11b0d499 17 12 CFR CFR NNP cord-354133-11b0d499 17 13 . . . cord-354133-11b0d499 18 1 It -PRON- PRP cord-354133-11b0d499 18 2 is be VBZ cord-354133-11b0d499 18 3 important important JJ cord-354133-11b0d499 18 4 to to TO cord-354133-11b0d499 18 5 accurately accurately RB cord-354133-11b0d499 18 6 quantify quantify VB cord-354133-11b0d499 18 7 the the DT cord-354133-11b0d499 18 8 CFR CFR NNP cord-354133-11b0d499 18 9 of of IN cord-354133-11b0d499 18 10 a a DT cord-354133-11b0d499 18 11 new new JJ cord-354133-11b0d499 18 12 disease disease NN cord-354133-11b0d499 18 13 to to TO cord-354133-11b0d499 18 14 inform inform VB cord-354133-11b0d499 18 15 policy policy NN cord-354133-11b0d499 18 16 , , , cord-354133-11b0d499 18 17 communication communication NN cord-354133-11b0d499 18 18 and and CC cord-354133-11b0d499 18 19 public public JJ cord-354133-11b0d499 18 20 health health NN cord-354133-11b0d499 18 21 measures measure NNS cord-354133-11b0d499 18 22 . . . cord-354133-11b0d499 19 1 Calculating calculate VBG cord-354133-11b0d499 19 2 the the DT cord-354133-11b0d499 19 3 case case NN cord-354133-11b0d499 19 4 fatality fatality NN cord-354133-11b0d499 19 5 ratio ratio NN cord-354133-11b0d499 19 6 requires require VBZ cord-354133-11b0d499 19 7 data datum NNS cord-354133-11b0d499 19 8 on on IN cord-354133-11b0d499 19 9 cases case NNS cord-354133-11b0d499 19 10 and and CC cord-354133-11b0d499 19 11 deaths death NNS cord-354133-11b0d499 19 12 over over IN cord-354133-11b0d499 19 13 time time NN cord-354133-11b0d499 19 14 , , , cord-354133-11b0d499 19 15 either either CC cord-354133-11b0d499 19 16 for for IN cord-354133-11b0d499 19 17 individuals individual NNS cord-354133-11b0d499 19 18 or or CC cord-354133-11b0d499 19 19 populations population NNS cord-354133-11b0d499 19 20 . . . cord-354133-11b0d499 20 1 In in IN cord-354133-11b0d499 20 2 general general JJ cord-354133-11b0d499 20 3 , , , cord-354133-11b0d499 20 4 the the DT cord-354133-11b0d499 20 5 CFR CFR NNP cord-354133-11b0d499 20 6 is be VBZ cord-354133-11b0d499 20 7 based base VBN cord-354133-11b0d499 20 8 on on IN cord-354133-11b0d499 20 9 diagnosed diagnosed JJ cord-354133-11b0d499 20 10 cases case NNS cord-354133-11b0d499 20 11 of of IN cord-354133-11b0d499 20 12 disease disease NN cord-354133-11b0d499 20 13 rather rather RB cord-354133-11b0d499 20 14 than than IN cord-354133-11b0d499 20 15 the the DT cord-354133-11b0d499 20 16 number number NN cord-354133-11b0d499 20 17 of of IN cord-354133-11b0d499 20 18 actual actual JJ cord-354133-11b0d499 20 19 infections infection NNS cord-354133-11b0d499 20 20 ( ( -LRB- cord-354133-11b0d499 20 21 which which WDT cord-354133-11b0d499 20 22 is be VBZ cord-354133-11b0d499 20 23 difficult difficult JJ cord-354133-11b0d499 20 24 to to TO cord-354133-11b0d499 20 25 measure measure VB cord-354133-11b0d499 20 26 ) ) -RRB- cord-354133-11b0d499 20 27 ; ; : cord-354133-11b0d499 20 28 there there EX cord-354133-11b0d499 20 29 may may MD cord-354133-11b0d499 20 30 be be VB cord-354133-11b0d499 20 31 many many JJ cord-354133-11b0d499 20 32 more more JJR cord-354133-11b0d499 20 33 infections infection NNS cord-354133-11b0d499 20 34 than than IN cord-354133-11b0d499 20 35 reported report VBN cord-354133-11b0d499 20 36 cases case NNS cord-354133-11b0d499 20 37 , , , cord-354133-11b0d499 20 38 depending depend VBG cord-354133-11b0d499 20 39 on on IN cord-354133-11b0d499 20 40 the the DT cord-354133-11b0d499 20 41 expression expression NN cord-354133-11b0d499 20 42 of of IN cord-354133-11b0d499 20 43 symptoms symptom NNS cord-354133-11b0d499 20 44 and and CC cord-354133-11b0d499 20 45 the the DT cord-354133-11b0d499 20 46 degree degree NN cord-354133-11b0d499 20 47 of of IN cord-354133-11b0d499 20 48 testing testing NN cord-354133-11b0d499 20 49 . . . cord-354133-11b0d499 21 1 The the DT cord-354133-11b0d499 21 2 simplest simple JJS cord-354133-11b0d499 21 3 estimate estimate NN cord-354133-11b0d499 21 4 of of IN cord-354133-11b0d499 21 5 CFR CFR NNP cord-354133-11b0d499 21 6 is be VBZ cord-354133-11b0d499 21 7 to to TO cord-354133-11b0d499 21 8 divide divide VB cord-354133-11b0d499 21 9 the the DT cord-354133-11b0d499 21 10 cumulative cumulative JJ cord-354133-11b0d499 21 11 number number NN cord-354133-11b0d499 21 12 of of IN cord-354133-11b0d499 21 13 deaths death NNS cord-354133-11b0d499 21 14 by by IN cord-354133-11b0d499 21 15 the the DT cord-354133-11b0d499 21 16 cumulative cumulative JJ cord-354133-11b0d499 21 17 number number NN cord-354133-11b0d499 21 18 of of IN cord-354133-11b0d499 21 19 cases case NNS cord-354133-11b0d499 21 20 at at IN cord-354133-11b0d499 21 21 a a DT cord-354133-11b0d499 21 22 given give VBN cord-354133-11b0d499 21 23 time time NN cord-354133-11b0d499 21 24 , , , cord-354133-11b0d499 21 25 known know VBN cord-354133-11b0d499 21 26 as as IN cord-354133-11b0d499 21 27 the the DT cord-354133-11b0d499 21 28 crude crude NN cord-354133-11b0d499 21 29 ( ( -LRB- cord-354133-11b0d499 21 30 or or CC cord-354133-11b0d499 21 31 naïve naïve JJ cord-354133-11b0d499 21 32 ) ) -RRB- cord-354133-11b0d499 21 33 CFR CFR NNP cord-354133-11b0d499 21 34 . . . cord-354133-11b0d499 22 1 However however RB cord-354133-11b0d499 22 2 , , , cord-354133-11b0d499 22 3 the the DT cord-354133-11b0d499 22 4 crude crude JJ cord-354133-11b0d499 22 5 CFR CFR NNP cord-354133-11b0d499 22 6 tends tend VBZ cord-354133-11b0d499 22 7 to to TO cord-354133-11b0d499 22 8 underestimate underestimate VB cord-354133-11b0d499 22 9 the the DT cord-354133-11b0d499 22 10 CFR CFR NNP cord-354133-11b0d499 22 11 during during IN cord-354133-11b0d499 22 12 an an DT cord-354133-11b0d499 22 13 outbreak outbreak NN cord-354133-11b0d499 22 14 because because IN cord-354133-11b0d499 22 15 at at IN cord-354133-11b0d499 22 16 any any DT cord-354133-11b0d499 22 17 given give VBN cord-354133-11b0d499 22 18 time time NN cord-354133-11b0d499 22 19 , , , cord-354133-11b0d499 22 20 some some DT cord-354133-11b0d499 22 21 of of IN cord-354133-11b0d499 22 22 the the DT cord-354133-11b0d499 22 23 existing exist VBG cord-354133-11b0d499 22 24 known know VBN cord-354133-11b0d499 22 25 cases case NNS cord-354133-11b0d499 22 26 will will MD cord-354133-11b0d499 22 27 prove prove VB cord-354133-11b0d499 22 28 fatal fatal JJ cord-354133-11b0d499 22 29 and and CC cord-354133-11b0d499 22 30 need need VBP cord-354133-11b0d499 22 31 to to TO cord-354133-11b0d499 22 32 be be VB cord-354133-11b0d499 22 33 included include VBN cord-354133-11b0d499 22 34 in in IN cord-354133-11b0d499 22 35 the the DT cord-354133-11b0d499 22 36 death death NN cord-354133-11b0d499 22 37 count count NN cord-354133-11b0d499 22 38 . . . cord-354133-11b0d499 23 1 This this DT cord-354133-11b0d499 23 2 bias bias NN cord-354133-11b0d499 23 3 is be VBZ cord-354133-11b0d499 23 4 known know VBN cord-354133-11b0d499 23 5 as as IN cord-354133-11b0d499 23 6 right right RB cord-354133-11b0d499 23 7 - - HYPH cord-354133-11b0d499 23 8 censoring censoring NN cord-354133-11b0d499 23 9 and and CC cord-354133-11b0d499 23 10 obscures obscure VBZ cord-354133-11b0d499 23 11 the the DT cord-354133-11b0d499 23 12 CFR CFR NNP cord-354133-11b0d499 23 13 of of IN cord-354133-11b0d499 23 14 a a DT cord-354133-11b0d499 23 15 new new JJ cord-354133-11b0d499 23 16 disease disease NN cord-354133-11b0d499 23 17 early early RB cord-354133-11b0d499 23 18 in in IN cord-354133-11b0d499 23 19 the the DT cord-354133-11b0d499 23 20 course course NN cord-354133-11b0d499 23 21 of of IN cord-354133-11b0d499 23 22 the the DT cord-354133-11b0d499 23 23 outbreak outbreak NN cord-354133-11b0d499 23 24 , , , cord-354133-11b0d499 23 25 particularly particularly RB cord-354133-11b0d499 23 26 before before IN cord-354133-11b0d499 23 27 the the DT cord-354133-11b0d499 23 28 time time NN cord-354133-11b0d499 23 29 course course NN cord-354133-11b0d499 23 30 of of IN cord-354133-11b0d499 23 31 the the DT cord-354133-11b0d499 23 32 disease disease NN cord-354133-11b0d499 23 33 is be VBZ cord-354133-11b0d499 23 34 characterised characterise VBN cord-354133-11b0d499 23 35 . . . cord-354133-11b0d499 24 1 Further further RB cord-354133-11b0d499 24 2 , , , cord-354133-11b0d499 24 3 even even RB cord-354133-11b0d499 24 4 once once IN cord-354133-11b0d499 24 5 the the DT cord-354133-11b0d499 24 6 distribution distribution NN cord-354133-11b0d499 24 7 of of IN cord-354133-11b0d499 24 8 times time NNS cord-354133-11b0d499 24 9 from from IN cord-354133-11b0d499 24 10 onset onset NN cord-354133-11b0d499 24 11 of of IN cord-354133-11b0d499 24 12 disease disease NN cord-354133-11b0d499 24 13 to to IN cord-354133-11b0d499 24 14 death death NN cord-354133-11b0d499 24 15 is be VBZ cord-354133-11b0d499 24 16 known know VBN cord-354133-11b0d499 24 17 , , , cord-354133-11b0d499 24 18 it -PRON- PRP cord-354133-11b0d499 24 19 can can MD cord-354133-11b0d499 24 20 be be VB cord-354133-11b0d499 24 21 difficult difficult JJ cord-354133-11b0d499 24 22 to to TO cord-354133-11b0d499 24 23 use use VB cord-354133-11b0d499 24 24 this this DT cord-354133-11b0d499 24 25 information information NN cord-354133-11b0d499 24 26 to to TO cord-354133-11b0d499 24 27 accurately accurately RB cord-354133-11b0d499 24 28 correct correct VB cord-354133-11b0d499 24 29 the the DT cord-354133-11b0d499 24 30 crude crude JJ cord-354133-11b0d499 24 31 CFR CFR NNP cord-354133-11b0d499 24 32 . . . cord-354133-11b0d499 25 1 An an DT cord-354133-11b0d499 25 2 alternative alternative JJ cord-354133-11b0d499 25 3 method method NN cord-354133-11b0d499 25 4 is be VBZ cord-354133-11b0d499 25 5 to to TO cord-354133-11b0d499 25 6 use use VB cord-354133-11b0d499 25 7 data datum NNS cord-354133-11b0d499 25 8 for for IN cord-354133-11b0d499 25 9 closed closed JJ cord-354133-11b0d499 25 10 cases case NNS cord-354133-11b0d499 25 11 only only RB cord-354133-11b0d499 25 12 , , , cord-354133-11b0d499 25 13 once once IN cord-354133-11b0d499 25 14 patients patient NNS cord-354133-11b0d499 25 15 have have VBP cord-354133-11b0d499 25 16 recovered recover VBN cord-354133-11b0d499 25 17 or or CC cord-354133-11b0d499 25 18 died die VBN cord-354133-11b0d499 25 19 ( ( -LRB- cord-354133-11b0d499 25 20 eg eg IN cord-354133-11b0d499 25 21 [ [ -LRB- cord-354133-11b0d499 25 22 7 7 CD cord-354133-11b0d499 25 23 , , , cord-354133-11b0d499 25 24 8 8 CD cord-354133-11b0d499 25 25 ] ] -RRB- cord-354133-11b0d499 25 26 ) ) -RRB- cord-354133-11b0d499 25 27 , , , cord-354133-11b0d499 25 28 yet yet CC cord-354133-11b0d499 25 29 this this DT cord-354133-11b0d499 25 30 information information NN cord-354133-11b0d499 25 31 is be VBZ cord-354133-11b0d499 25 32 also also RB cord-354133-11b0d499 25 33 difficult difficult JJ cord-354133-11b0d499 25 34 to to TO cord-354133-11b0d499 25 35 obtain obtain VB cord-354133-11b0d499 25 36 during during IN cord-354133-11b0d499 25 37 an an DT cord-354133-11b0d499 25 38 outbreak outbreak NN cord-354133-11b0d499 25 39 and and CC cord-354133-11b0d499 25 40 may may MD cord-354133-11b0d499 25 41 be be VB cord-354133-11b0d499 25 42 biased bias VBN cord-354133-11b0d499 25 43 towards towards IN cord-354133-11b0d499 25 44 a a DT cord-354133-11b0d499 25 45 particular particular JJ cord-354133-11b0d499 25 46 demographic demographic NN cord-354133-11b0d499 25 47 or or CC cord-354133-11b0d499 25 48 . . . cord-354133-11b0d499 26 1 CC CC NNP cord-354133-11b0d499 26 2 - - HYPH cord-354133-11b0d499 26 3 BY BY NNP cord-354133-11b0d499 26 4 - - HYPH cord-354133-11b0d499 26 5 NC NC NNP cord-354133-11b0d499 26 6 - - HYPH cord-354133-11b0d499 26 7 ND ND NNP cord-354133-11b0d499 26 8 4.0 4.0 CD cord-354133-11b0d499 26 9 International international JJ cord-354133-11b0d499 26 10 license license NN cord-354133-11b0d499 26 11 It -PRON- PRP cord-354133-11b0d499 26 12 is be VBZ cord-354133-11b0d499 26 13 made make VBN cord-354133-11b0d499 26 14 available available JJ cord-354133-11b0d499 26 15 under under IN cord-354133-11b0d499 26 16 a a DT cord-354133-11b0d499 26 17 perpetuity perpetuity NN cord-354133-11b0d499 26 18 . . . cord-354133-11b0d499 27 1 is be VBZ cord-354133-11b0d499 27 2 the the DT cord-354133-11b0d499 27 3 author author NN cord-354133-11b0d499 27 4 / / SYM cord-354133-11b0d499 27 5 funder funder NN cord-354133-11b0d499 27 6 , , , cord-354133-11b0d499 27 7 who who WP cord-354133-11b0d499 27 8 has have VBZ cord-354133-11b0d499 27 9 granted grant VBN cord-354133-11b0d499 27 10 medRxiv medRxiv NNS cord-354133-11b0d499 27 11 a a DT cord-354133-11b0d499 27 12 license license NN cord-354133-11b0d499 27 13 to to TO cord-354133-11b0d499 27 14 display display VB cord-354133-11b0d499 27 15 the the DT cord-354133-11b0d499 27 16 preprint preprint NN cord-354133-11b0d499 27 17 in in IN cord-354133-11b0d499 27 18 ( ( -LRB- cord-354133-11b0d499 27 19 which which WDT cord-354133-11b0d499 27 20 was be VBD cord-354133-11b0d499 27 21 not not RB cord-354133-11b0d499 27 22 certified certify VBN cord-354133-11b0d499 27 23 by by IN cord-354133-11b0d499 27 24 peer peer NN cord-354133-11b0d499 27 25 review review NN cord-354133-11b0d499 27 26 ) ) -RRB- cord-354133-11b0d499 27 27 preprint preprint NN cord-354133-11b0d499 28 1 The the DT cord-354133-11b0d499 28 2 copyright copyright NN cord-354133-11b0d499 28 3 holder holder NN cord-354133-11b0d499 28 4 for for IN cord-354133-11b0d499 28 5 this this DT cord-354133-11b0d499 28 6 this this DT cord-354133-11b0d499 28 7 version version NN cord-354133-11b0d499 28 8 posted post VBD cord-354133-11b0d499 28 9 October October NNP cord-354133-11b0d499 28 10 27 27 CD cord-354133-11b0d499 28 11 , , , cord-354133-11b0d499 28 12 2020 2020 CD cord-354133-11b0d499 28 13 . . . cord-354133-11b0d499 29 1 ; ; : cord-354133-11b0d499 29 2 https://doi.org/10.1101/2020 https://doi.org/10.1101/2020 NN cord-354133-11b0d499 29 3 . . . cord-354133-11b0d499 30 1 10.25.20216671 10.25.20216671 CD cord-354133-11b0d499 30 2 doi doi NN cord-354133-11b0d499 30 3 : : : cord-354133-11b0d499 31 1 medRxiv medRxiv NNS cord-354133-11b0d499 31 2 preprint preprint NN cord-354133-11b0d499 31 3 3 3 CD cord-354133-11b0d499 31 4 skewed skewed JJ cord-354133-11b0d499 31 5 by by IN cord-354133-11b0d499 31 6 delays delay NNS cord-354133-11b0d499 31 7 in in IN cord-354133-11b0d499 31 8 reporting reporting NN cord-354133-11b0d499 31 9 of of IN cord-354133-11b0d499 31 10 recoveries recovery NNS cord-354133-11b0d499 31 11 . . . cord-354133-11b0d499 32 1 Other other JJ cord-354133-11b0d499 32 2 biases bias NNS cord-354133-11b0d499 32 3 in in IN cord-354133-11b0d499 32 4 calculating calculate VBG cord-354133-11b0d499 32 5 CFR CFR NNP cord-354133-11b0d499 32 6 include include VBP cord-354133-11b0d499 32 7 underascertainment underascertainment NN cord-354133-11b0d499 32 8 of of IN cord-354133-11b0d499 32 9 mild mild JJ cord-354133-11b0d499 32 10 or or CC cord-354133-11b0d499 32 11 asymptomatic asymptomatic JJ cord-354133-11b0d499 32 12 cases case NNS cord-354133-11b0d499 32 13 , , , cord-354133-11b0d499 32 14 time time NN cord-354133-11b0d499 32 15 lags lag VBZ cord-354133-11b0d499 32 16 in in IN cord-354133-11b0d499 32 17 testing testing NN cord-354133-11b0d499 32 18 and and CC cord-354133-11b0d499 32 19 reporting reporting NN cord-354133-11b0d499 32 20 , , , cord-354133-11b0d499 32 21 and and CC cord-354133-11b0d499 32 22 the the DT cord-354133-11b0d499 32 23 effects effect NNS cord-354133-11b0d499 32 24 of of IN cord-354133-11b0d499 32 25 intervention intervention NN cord-354133-11b0d499 32 26 approach approach NN cord-354133-11b0d499 32 27 , , , cord-354133-11b0d499 32 28 demographics demographic NNS cord-354133-11b0d499 32 29 and and CC cord-354133-11b0d499 32 30 reporting reporting NN cord-354133-11b0d499 32 31 schemes scheme NNS cord-354133-11b0d499 32 32 [ [ -LRB- cord-354133-11b0d499 32 33 9 9 CD cord-354133-11b0d499 32 34 ] ] -RRB- cord-354133-11b0d499 32 35 . . . cord-354133-11b0d499 33 1 There there EX cord-354133-11b0d499 33 2 are be VBP cord-354133-11b0d499 33 3 many many JJ cord-354133-11b0d499 33 4 published publish VBN cord-354133-11b0d499 33 5 calculations calculation NNS cord-354133-11b0d499 33 6 of of IN cord-354133-11b0d499 33 7 case case NN cord-354133-11b0d499 33 8 fatality fatality NN cord-354133-11b0d499 33 9 ratios ratio NNS cord-354133-11b0d499 33 10 for for IN cord-354133-11b0d499 33 11 COVID-19 covid-19 NN cord-354133-11b0d499 33 12 using use VBG cord-354133-11b0d499 33 13 various various JJ cord-354133-11b0d499 33 14 datasets dataset NNS cord-354133-11b0d499 33 15 from from IN cord-354133-11b0d499 33 16 different different JJ cord-354133-11b0d499 33 17 countries country NNS cord-354133-11b0d499 33 18 and and CC cord-354133-11b0d499 33 19 using use VBG cord-354133-11b0d499 33 20 a a DT cord-354133-11b0d499 33 21 range range NN cord-354133-11b0d499 33 22 of of IN cord-354133-11b0d499 33 23 methods method NNS cord-354133-11b0d499 33 24 . . . cord-354133-11b0d499 34 1 In in IN cord-354133-11b0d499 34 2 some some DT cord-354133-11b0d499 34 3 places place NNS cord-354133-11b0d499 34 4 , , , cord-354133-11b0d499 34 5 initial initial JJ cord-354133-11b0d499 34 6 outbreaks outbreak NNS cord-354133-11b0d499 34 7 have have VBP cord-354133-11b0d499 34 8 now now RB cord-354133-11b0d499 34 9 concluded conclude VBN cord-354133-11b0d499 34 10 and and CC cord-354133-11b0d499 34 11 the the DT cord-354133-11b0d499 34 12 final final JJ cord-354133-11b0d499 34 13 crude crude NN cord-354133-11b0d499 34 14 CFR CFR NNP cord-354133-11b0d499 34 15 accurately accurately RB cord-354133-11b0d499 34 16 reflects reflect VBZ cord-354133-11b0d499 34 17 the the DT cord-354133-11b0d499 34 18 overall overall JJ cord-354133-11b0d499 34 19 ratio ratio NN cord-354133-11b0d499 34 20 of of IN cord-354133-11b0d499 34 21 reported report VBN cord-354133-11b0d499 34 22 deaths death NNS cord-354133-11b0d499 34 23 to to IN cord-354133-11b0d499 34 24 cases case NNS cord-354133-11b0d499 34 25 . . . cord-354133-11b0d499 35 1 In in IN cord-354133-11b0d499 35 2 many many JJ cord-354133-11b0d499 35 3 other other JJ cord-354133-11b0d499 35 4 places place NNS cord-354133-11b0d499 35 5 , , , cord-354133-11b0d499 35 6 outbreaks outbreak NNS cord-354133-11b0d499 35 7 are be VBP cord-354133-11b0d499 35 8 continuing continue VBG cord-354133-11b0d499 35 9 . . . cord-354133-11b0d499 36 1 Questions question NNS cord-354133-11b0d499 36 2 remain remain VBP cord-354133-11b0d499 36 3 regarding regard VBG cord-354133-11b0d499 36 4 quality quality NN cord-354133-11b0d499 36 5 of of IN cord-354133-11b0d499 36 6 data datum NNS cord-354133-11b0d499 36 7 , , , cord-354133-11b0d499 36 8 methods method NNS cord-354133-11b0d499 36 9 of of IN cord-354133-11b0d499 36 10 calculation calculation NN cord-354133-11b0d499 36 11 and and CC cord-354133-11b0d499 36 12 even even RB cord-354133-11b0d499 36 13 the the DT cord-354133-11b0d499 36 14 possibility possibility NN cord-354133-11b0d499 36 15 of of IN cord-354133-11b0d499 36 16 changes change NNS cord-354133-11b0d499 36 17 in in IN cord-354133-11b0d499 36 18 the the DT cord-354133-11b0d499 36 19 CFR CFR NNP cord-354133-11b0d499 36 20 over over IN cord-354133-11b0d499 36 21 time time NN cord-354133-11b0d499 36 22 . . . cord-354133-11b0d499 37 1 These these DT cord-354133-11b0d499 37 2 continuing continue VBG cord-354133-11b0d499 37 3 uncertainties uncertainty NNS cord-354133-11b0d499 37 4 make make VBP cord-354133-11b0d499 37 5 it -PRON- PRP cord-354133-11b0d499 37 6 necessary necessary JJ cord-354133-11b0d499 37 7 to to TO cord-354133-11b0d499 37 8 improve improve VB cord-354133-11b0d499 37 9 estimates estimate NNS cord-354133-11b0d499 37 10 of of IN cord-354133-11b0d499 37 11 the the DT cord-354133-11b0d499 37 12 CFR CFR NNP cord-354133-11b0d499 37 13 by by IN cord-354133-11b0d499 37 14 refining refine VBG cord-354133-11b0d499 37 15 the the DT cord-354133-11b0d499 37 16 methods method NNS cord-354133-11b0d499 37 17 used use VBN cord-354133-11b0d499 37 18 to to TO cord-354133-11b0d499 37 19 calculate calculate VB cord-354133-11b0d499 37 20 it -PRON- PRP cord-354133-11b0d499 37 21 . . . cord-354133-11b0d499 38 1 In in IN cord-354133-11b0d499 38 2 essence essence NN cord-354133-11b0d499 38 3 , , , cord-354133-11b0d499 38 4 this this DT cord-354133-11b0d499 38 5 means mean VBZ cord-354133-11b0d499 38 6 finding find VBG cord-354133-11b0d499 38 7 the the DT cord-354133-11b0d499 38 8 best good JJS cord-354133-11b0d499 38 9 way way NN cord-354133-11b0d499 38 10 to to TO cord-354133-11b0d499 38 11 correct correct VB cord-354133-11b0d499 38 12 the the DT cord-354133-11b0d499 38 13 crude crude JJ cord-354133-11b0d499 38 14 CFR CFR NNP cord-354133-11b0d499 38 15 for for IN cord-354133-11b0d499 38 16 biases bias NNS cord-354133-11b0d499 38 17 due due JJ cord-354133-11b0d499 38 18 to to IN cord-354133-11b0d499 38 19 time time NN cord-354133-11b0d499 38 20 lags lag NNS cord-354133-11b0d499 38 21 and and CC cord-354133-11b0d499 38 22 other other JJ cord-354133-11b0d499 38 23 factors factor NNS cord-354133-11b0d499 38 24 . . . cord-354133-11b0d499 39 1 Most most RBS cord-354133-11b0d499 39 2 previously previously RB cord-354133-11b0d499 39 3 published publish VBN cord-354133-11b0d499 39 4 studies study NNS cord-354133-11b0d499 39 5 make make VBP cord-354133-11b0d499 39 6 use use NN cord-354133-11b0d499 39 7 of of IN cord-354133-11b0d499 39 8 a a DT cord-354133-11b0d499 39 9 parametrised parametrised JJ cord-354133-11b0d499 39 10 distribution distribution NN cord-354133-11b0d499 39 11 of of IN cord-354133-11b0d499 39 12 times time NNS cord-354133-11b0d499 39 13 from from IN cord-354133-11b0d499 39 14 onset onset NN cord-354133-11b0d499 39 15 ( ( -LRB- cord-354133-11b0d499 39 16 or or CC cord-354133-11b0d499 39 17 hospitalisation hospitalisation NN cord-354133-11b0d499 39 18 ) ) -RRB- cord-354133-11b0d499 39 19 to to IN cord-354133-11b0d499 39 20 death death NN cord-354133-11b0d499 39 21 , , , cord-354133-11b0d499 39 22 determined determine VBN cord-354133-11b0d499 39 23 from from IN cord-354133-11b0d499 39 24 individual individual JJ cord-354133-11b0d499 39 25 case case NN cord-354133-11b0d499 39 26 data datum NNS cord-354133-11b0d499 39 27 from from IN cord-354133-11b0d499 39 28 early early RB cord-354133-11b0d499 39 29 in in IN cord-354133-11b0d499 39 30 the the DT cord-354133-11b0d499 39 31 outbreak outbreak NN cord-354133-11b0d499 39 32 ( ( -LRB- cord-354133-11b0d499 39 33 largely largely RB cord-354133-11b0d499 39 34 from from IN cord-354133-11b0d499 39 35 China China NNP cord-354133-11b0d499 39 36 ) ) -RRB- cord-354133-11b0d499 39 37 [ [ -LRB- cord-354133-11b0d499 39 38 5 5 CD cord-354133-11b0d499 39 39 , , , cord-354133-11b0d499 39 40 [ [ -LRB- cord-354133-11b0d499 39 41 10 10 CD cord-354133-11b0d499 39 42 ] ] -RRB- cord-354133-11b0d499 39 43 [ [ -LRB- cord-354133-11b0d499 39 44 11 11 CD cord-354133-11b0d499 39 45 ] ] -RRB- cord-354133-11b0d499 39 46 [ [ -LRB- cord-354133-11b0d499 39 47 12 12 CD cord-354133-11b0d499 39 48 ] ] -RRB- cord-354133-11b0d499 39 49 , , , cord-354133-11b0d499 39 50 which which WDT cord-354133-11b0d499 39 51 is be VBZ cord-354133-11b0d499 39 52 then then RB cord-354133-11b0d499 39 53 used use VBN cord-354133-11b0d499 39 54 in in IN cord-354133-11b0d499 39 55 combination combination NN cord-354133-11b0d499 39 56 with with IN cord-354133-11b0d499 39 57 statistical statistical JJ cord-354133-11b0d499 39 58 methods method NNS cord-354133-11b0d499 39 59 to to TO cord-354133-11b0d499 39 60 estimate estimate VB cord-354133-11b0d499 39 61 the the DT cord-354133-11b0d499 39 62 CFR CFR NNP cord-354133-11b0d499 39 63 using use VBG cord-354133-11b0d499 39 64 population population NN cord-354133-11b0d499 39 65 - - HYPH cord-354133-11b0d499 39 66 level level NN cord-354133-11b0d499 39 67 data datum NNS cord-354133-11b0d499 39 68 on on IN cord-354133-11b0d499 39 69 cases case NNS cord-354133-11b0d499 39 70 and and CC cord-354133-11b0d499 39 71 deaths death NNS cord-354133-11b0d499 39 72 [ [ -LRB- cord-354133-11b0d499 39 73 5 5 CD cord-354133-11b0d499 39 74 , , , cord-354133-11b0d499 39 75 10 10 CD cord-354133-11b0d499 39 76 , , , cord-354133-11b0d499 39 77 11 11 CD cord-354133-11b0d499 39 78 , , , cord-354133-11b0d499 39 79 13 13 CD cord-354133-11b0d499 39 80 ] ] -RRB- cord-354133-11b0d499 39 81 . . . cord-354133-11b0d499 40 1 Various various JJ cord-354133-11b0d499 40 2 assumptions assumption NNS cord-354133-11b0d499 40 3 are be VBP cord-354133-11b0d499 40 4 made make VBN cord-354133-11b0d499 40 5 in in IN cord-354133-11b0d499 40 6 these these DT cord-354133-11b0d499 40 7 analyses analysis NNS cord-354133-11b0d499 40 8 , , , cord-354133-11b0d499 40 9 including include VBG cord-354133-11b0d499 40 10 the the DT cord-354133-11b0d499 40 11 form form NN cord-354133-11b0d499 40 12 ( ( -LRB- cord-354133-11b0d499 40 13 and and CC cord-354133-11b0d499 40 14 transferability transferability NN cord-354133-11b0d499 40 15 ) ) -RRB- cord-354133-11b0d499 40 16 of of IN cord-354133-11b0d499 40 17 the the DT cord-354133-11b0d499 40 18 time time NN cord-354133-11b0d499 40 19 course course NN cord-354133-11b0d499 40 20 of of IN cord-354133-11b0d499 40 21 cases case NNS cord-354133-11b0d499 40 22 , , , cord-354133-11b0d499 40 23 time time NN cord-354133-11b0d499 40 24 lags lag VBZ cord-354133-11b0d499 40 25 in in IN cord-354133-11b0d499 40 26 reporting report VBG cord-354133-11b0d499 40 27 or or CC cord-354133-11b0d499 40 28 testing testing NN cord-354133-11b0d499 40 29 or or CC cord-354133-11b0d499 40 30 hospitalisation hospitalisation NN cord-354133-11b0d499 40 31 , , , cord-354133-11b0d499 40 32 and and CC cord-354133-11b0d499 40 33 estimates estimate NNS cord-354133-11b0d499 40 34 of of IN cord-354133-11b0d499 40 35 the the DT cord-354133-11b0d499 40 36 proportion proportion NN cord-354133-11b0d499 40 37 of of IN cord-354133-11b0d499 40 38 cases case NNS cord-354133-11b0d499 40 39 being be VBG cord-354133-11b0d499 40 40 detected detect VBN cord-354133-11b0d499 40 41 . . . cord-354133-11b0d499 41 1 Early early JJ cord-354133-11b0d499 41 2 values value NNS cord-354133-11b0d499 41 3 of of IN cord-354133-11b0d499 41 4 CFR CFR NNP cord-354133-11b0d499 41 5 obtained obtain VBD cord-354133-11b0d499 41 6 using use VBG cord-354133-11b0d499 41 7 these these DT cord-354133-11b0d499 41 8 methods method NNS cord-354133-11b0d499 41 9 range range VBP cord-354133-11b0d499 41 10 from from IN cord-354133-11b0d499 41 11 1 1 CD cord-354133-11b0d499 41 12 - - SYM cord-354133-11b0d499 41 13 18 18 CD cord-354133-11b0d499 41 14 % % NN cord-354133-11b0d499 41 15 , , , cord-354133-11b0d499 41 16 with with IN cord-354133-11b0d499 41 17 the the DT cord-354133-11b0d499 41 18 highest high JJS cord-354133-11b0d499 41 19 values value NNS cord-354133-11b0d499 41 20 obtained obtain VBN cord-354133-11b0d499 41 21 for for IN cord-354133-11b0d499 41 22 China China NNP cord-354133-11b0d499 41 23 : : : cord-354133-11b0d499 41 24 4 4 CD cord-354133-11b0d499 41 25 - - SYM cord-354133-11b0d499 41 26 18 18 CD cord-354133-11b0d499 41 27 % % NN cord-354133-11b0d499 41 28 early early RB cord-354133-11b0d499 41 29 in in IN cord-354133-11b0d499 41 30 the the DT cord-354133-11b0d499 41 31 outbreak outbreak NN cord-354133-11b0d499 41 32 [ [ -LRB- cord-354133-11b0d499 41 33 5 5 CD cord-354133-11b0d499 41 34 , , , cord-354133-11b0d499 41 35 10 10 CD cord-354133-11b0d499 41 36 ] ] -RRB- cord-354133-11b0d499 41 37 , , , cord-354133-11b0d499 41 38 12 12 CD cord-354133-11b0d499 41 39 % % NN cord-354133-11b0d499 41 40 in in IN cord-354133-11b0d499 41 41 Wuhan Wuhan NNP cord-354133-11b0d499 41 42 and and CC cord-354133-11b0d499 41 43 as as RB cord-354133-11b0d499 41 44 low low JJ cord-354133-11b0d499 41 45 as as IN cord-354133-11b0d499 41 46 1 1 CD cord-354133-11b0d499 41 47 % % NN cord-354133-11b0d499 41 48 outside outside IN cord-354133-11b0d499 41 49 Hubei Hubei NNP cord-354133-11b0d499 41 50 province province NN cord-354133-11b0d499 41 51 [ [ -LRB- cord-354133-11b0d499 41 52 11 11 CD cord-354133-11b0d499 41 53 ] ] -RRB- cord-354133-11b0d499 41 54 . . . cord-354133-11b0d499 42 1 Values value NNS cord-354133-11b0d499 42 2 reported report VBN cord-354133-11b0d499 42 3 outside outside IN cord-354133-11b0d499 42 4 China China NNP cord-354133-11b0d499 42 5 include include VBP cord-354133-11b0d499 42 6 1 1 CD cord-354133-11b0d499 42 7 - - SYM cord-354133-11b0d499 42 8 5 5 CD cord-354133-11b0d499 42 9 % % NN cord-354133-11b0d499 42 10 for for IN cord-354133-11b0d499 42 11 early early JJ cord-354133-11b0d499 42 12 cases case NNS cord-354133-11b0d499 42 13 in in IN cord-354133-11b0d499 42 14 travellers traveller NNS cord-354133-11b0d499 42 15 [ [ -LRB- cord-354133-11b0d499 42 16 5 5 CD cord-354133-11b0d499 42 17 , , , cord-354133-11b0d499 42 18 10 10 CD cord-354133-11b0d499 42 19 ] ] -RRB- cord-354133-11b0d499 42 20 , , , cord-354133-11b0d499 42 21 and and CC cord-354133-11b0d499 42 22 1 1 CD cord-354133-11b0d499 42 23 - - SYM cord-354133-11b0d499 42 24 4 4 CD cord-354133-11b0d499 42 25 % % NN cord-354133-11b0d499 42 26 in in IN cord-354133-11b0d499 42 27 Korea Korea NNP cord-354133-11b0d499 42 28 [ [ -LRB- cord-354133-11b0d499 42 29 13 13 CD cord-354133-11b0d499 42 30 ] ] -RRB- cord-354133-11b0d499 42 31 . . . cord-354133-11b0d499 43 1 Case case NN cord-354133-11b0d499 43 2 fatality fatality NN cord-354133-11b0d499 43 3 ratios ratio NNS cord-354133-11b0d499 43 4 have have VBP cord-354133-11b0d499 43 5 also also RB cord-354133-11b0d499 43 6 been be VBN cord-354133-11b0d499 43 7 shown show VBN cord-354133-11b0d499 43 8 to to TO cord-354133-11b0d499 43 9 vary vary VB cord-354133-11b0d499 43 10 greatly greatly RB cord-354133-11b0d499 43 11 with with IN cord-354133-11b0d499 43 12 the the DT cord-354133-11b0d499 43 13 age age NN cord-354133-11b0d499 43 14 of of IN cord-354133-11b0d499 43 15 the the DT cord-354133-11b0d499 43 16 patient patient NN cord-354133-11b0d499 43 17 [ [ -LRB- cord-354133-11b0d499 43 18 5 5 CD cord-354133-11b0d499 43 19 ] ] -RRB- cord-354133-11b0d499 43 20 , , , cord-354133-11b0d499 43 21 which which WDT cord-354133-11b0d499 43 22 limits limit VBZ cord-354133-11b0d499 43 23 the the DT cord-354133-11b0d499 43 24 transferability transferability NN cord-354133-11b0d499 43 25 of of IN cord-354133-11b0d499 43 26 parameters parameter NNS cord-354133-11b0d499 43 27 based base VBN cord-354133-11b0d499 43 28 on on IN cord-354133-11b0d499 43 29 case case NN cord-354133-11b0d499 43 30 studies study NNS cord-354133-11b0d499 43 31 . . . cord-354133-11b0d499 44 1 The the DT cord-354133-11b0d499 44 2 specific specific JJ cord-354133-11b0d499 44 3 data data NN cord-354133-11b0d499 44 4 requirements requirement NNS cord-354133-11b0d499 44 5 and and CC cord-354133-11b0d499 44 6 the the DT cord-354133-11b0d499 44 7 range range NN cord-354133-11b0d499 44 8 of of IN cord-354133-11b0d499 44 9 approximations approximation NNS cord-354133-11b0d499 44 10 and and CC cord-354133-11b0d499 44 11 assumptions assumption NNS cord-354133-11b0d499 44 12 required require VBN cord-354133-11b0d499 44 13 by by IN cord-354133-11b0d499 44 14 statistical statistical JJ cord-354133-11b0d499 44 15 methods method NNS cord-354133-11b0d499 44 16 can can MD cord-354133-11b0d499 44 17 make make VB cord-354133-11b0d499 44 18 it -PRON- PRP cord-354133-11b0d499 44 19 difficult difficult JJ cord-354133-11b0d499 44 20 to to TO cord-354133-11b0d499 44 21 interpret interpret VB cord-354133-11b0d499 44 22 or or CC cord-354133-11b0d499 44 23 rely rely VB cord-354133-11b0d499 44 24 on on IN cord-354133-11b0d499 44 25 the the DT cord-354133-11b0d499 44 26 results result NNS cord-354133-11b0d499 44 27 of of IN cord-354133-11b0d499 44 28 such such JJ cord-354133-11b0d499 44 29 analyses analysis NNS cord-354133-11b0d499 44 30 , , , cord-354133-11b0d499 44 31 since since IN cord-354133-11b0d499 44 32 biases bias NNS cord-354133-11b0d499 44 33 can can MD cord-354133-11b0d499 44 34 be be VB cord-354133-11b0d499 44 35 obscured obscure VBN cord-354133-11b0d499 44 36 . . . cord-354133-11b0d499 45 1 is be VBZ cord-354133-11b0d499 45 2 the the DT cord-354133-11b0d499 45 3 author author NN cord-354133-11b0d499 45 4 / / SYM cord-354133-11b0d499 45 5 funder funder NN cord-354133-11b0d499 45 6 , , , cord-354133-11b0d499 45 7 who who WP cord-354133-11b0d499 45 8 has have VBZ cord-354133-11b0d499 45 9 granted grant VBN cord-354133-11b0d499 45 10 medRxiv medRxiv NNS cord-354133-11b0d499 45 11 a a DT cord-354133-11b0d499 45 12 license license NN cord-354133-11b0d499 45 13 to to TO cord-354133-11b0d499 45 14 display display VB cord-354133-11b0d499 45 15 the the DT cord-354133-11b0d499 45 16 preprint preprint NN cord-354133-11b0d499 45 17 in in IN cord-354133-11b0d499 45 18 ( ( -LRB- cord-354133-11b0d499 45 19 which which WDT cord-354133-11b0d499 45 20 was be VBD cord-354133-11b0d499 45 21 not not RB cord-354133-11b0d499 45 22 certified certify VBN cord-354133-11b0d499 45 23 by by IN cord-354133-11b0d499 45 24 peer peer NN cord-354133-11b0d499 45 25 review review NN cord-354133-11b0d499 45 26 ) ) -RRB- cord-354133-11b0d499 45 27 preprint preprint NN cord-354133-11b0d499 46 1 The the DT cord-354133-11b0d499 46 2 copyright copyright NN cord-354133-11b0d499 46 3 holder holder NN cord-354133-11b0d499 46 4 for for IN cord-354133-11b0d499 46 5 this this DT cord-354133-11b0d499 46 6 this this DT cord-354133-11b0d499 46 7 version version NN cord-354133-11b0d499 46 8 posted post VBD cord-354133-11b0d499 46 9 October October NNP cord-354133-11b0d499 46 10 27 27 CD cord-354133-11b0d499 46 11 , , , cord-354133-11b0d499 46 12 2020 2020 CD cord-354133-11b0d499 46 13 . . . cord-354133-11b0d499 47 1 ; ; : cord-354133-11b0d499 47 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 47 3 doi doi NN cord-354133-11b0d499 47 4 : : : cord-354133-11b0d499 48 1 medRxiv medRxiv NNP cord-354133-11b0d499 48 2 preprint preprint NNP cord-354133-11b0d499 49 1 The the DT cord-354133-11b0d499 49 2 time time NN cord-354133-11b0d499 49 3 - - HYPH cord-354133-11b0d499 49 4 shifted shift VBN cord-354133-11b0d499 49 5 distribution distribution NN cord-354133-11b0d499 49 6 ( ( -LRB- cord-354133-11b0d499 49 7 TSD TSD NNP cord-354133-11b0d499 49 8 ) ) -RRB- cord-354133-11b0d499 49 9 analysis analysis NN cord-354133-11b0d499 49 10 method method NN cord-354133-11b0d499 49 11 began begin VBD cord-354133-11b0d499 49 12 with with IN cord-354133-11b0d499 49 13 an an DT cord-354133-11b0d499 49 14 observation observation NN cord-354133-11b0d499 49 15 that that IN cord-354133-11b0d499 49 16 the the DT cord-354133-11b0d499 49 17 shape shape NN cord-354133-11b0d499 49 18 of of IN cord-354133-11b0d499 49 19 the the DT cord-354133-11b0d499 49 20 evolving evolve VBG cord-354133-11b0d499 49 21 time time NN cord-354133-11b0d499 49 22 distribution distribution NN cord-354133-11b0d499 49 23 of of IN cord-354133-11b0d499 49 24 COVID-19 covid-19 JJ cord-354133-11b0d499 49 25 cases case NNS cord-354133-11b0d499 49 26 in in IN cord-354133-11b0d499 49 27 a a DT cord-354133-11b0d499 49 28 given give VBN cord-354133-11b0d499 49 29 country country NN cord-354133-11b0d499 49 30 often often RB cord-354133-11b0d499 49 31 closely closely RB cord-354133-11b0d499 49 32 matches match VBZ cord-354133-11b0d499 49 33 the the DT cord-354133-11b0d499 49 34 shape shape NN cord-354133-11b0d499 49 35 of of IN cord-354133-11b0d499 49 36 the the DT cord-354133-11b0d499 49 37 corresponding corresponding JJ cord-354133-11b0d499 49 38 distribution distribution NN cord-354133-11b0d499 49 39 of of IN cord-354133-11b0d499 49 40 COVID-19 covid-19 JJ cord-354133-11b0d499 49 41 deaths death NNS cord-354133-11b0d499 49 42 -simply -simply VBP cord-354133-11b0d499 49 43 shifted shift VBN cord-354133-11b0d499 49 44 by by IN cord-354133-11b0d499 49 45 a a DT cord-354133-11b0d499 49 46 number number NN cord-354133-11b0d499 49 47 of of IN cord-354133-11b0d499 49 48 days day NNS cord-354133-11b0d499 49 49 and and CC cord-354133-11b0d499 49 50 linearly linearly RB cord-354133-11b0d499 49 51 scaled scale VBN cord-354133-11b0d499 49 52 in in IN cord-354133-11b0d499 49 53 magnitude magnitude NN cord-354133-11b0d499 49 54 . . . cord-354133-11b0d499 50 1 This this DT cord-354133-11b0d499 50 2 is be VBZ cord-354133-11b0d499 50 3 illustrated illustrate VBN cord-354133-11b0d499 50 4 in in IN cord-354133-11b0d499 50 5 Figure Figure NNP cord-354133-11b0d499 50 6 1 1 CD cord-354133-11b0d499 50 7 for for IN cord-354133-11b0d499 50 8 COVID-19 covid-19 JJ cord-354133-11b0d499 50 9 cases case NNS cord-354133-11b0d499 50 10 and and CC cord-354133-11b0d499 50 11 deaths death NNS cord-354133-11b0d499 50 12 in in IN cord-354133-11b0d499 50 13 Italy Italy NNP cord-354133-11b0d499 51 1 ( ( -LRB- cord-354133-11b0d499 51 2 data datum NNS cord-354133-11b0d499 51 3 from from IN cord-354133-11b0d499 51 4 [ [ -LRB- cord-354133-11b0d499 51 5 14 14 CD cord-354133-11b0d499 51 6 ] ] -RRB- cord-354133-11b0d499 51 7 , , , cord-354133-11b0d499 51 8 3-day 3-day JJ cord-354133-11b0d499 51 9 averaged average VBN cord-354133-11b0d499 51 10 data datum NNS cord-354133-11b0d499 51 11 shown show VBN cord-354133-11b0d499 51 12 ) ) -RRB- cord-354133-11b0d499 51 13 ; ; : cord-354133-11b0d499 51 14 the the DT cord-354133-11b0d499 51 15 time time NN cord-354133-11b0d499 51 16 - - HYPH cord-354133-11b0d499 51 17 shifted shift VBN cord-354133-11b0d499 51 18 relationship relationship NN cord-354133-11b0d499 51 19 between between IN cord-354133-11b0d499 51 20 case case NN cord-354133-11b0d499 51 21 and and CC cord-354133-11b0d499 51 22 death death NN cord-354133-11b0d499 51 23 distributions distribution NNS cord-354133-11b0d499 51 24 can can MD cord-354133-11b0d499 51 25 be be VB cord-354133-11b0d499 51 26 seen see VBN cord-354133-11b0d499 51 27 in in IN cord-354133-11b0d499 51 28 both both DT cord-354133-11b0d499 51 29 cumulative cumulative JJ cord-354133-11b0d499 51 30 and and CC cord-354133-11b0d499 51 31 daily daily JJ cord-354133-11b0d499 51 32 tallies tally NNS cord-354133-11b0d499 51 33 . . . cord-354133-11b0d499 52 1 We -PRON- PRP cord-354133-11b0d499 52 2 can can MD cord-354133-11b0d499 52 3 understand understand VB cord-354133-11b0d499 52 4 this this DT cord-354133-11b0d499 52 5 shift shift NN cord-354133-11b0d499 52 6 from from IN cord-354133-11b0d499 52 7 the the DT cord-354133-11b0d499 52 8 perspective perspective NN cord-354133-11b0d499 52 9 of of IN cord-354133-11b0d499 52 10 the the DT cord-354133-11b0d499 52 11 time time NN cord-354133-11b0d499 52 12 delay delay NN cord-354133-11b0d499 52 13 between between IN cord-354133-11b0d499 52 14 diagnosis diagnosis NN cord-354133-11b0d499 52 15 and and CC cord-354133-11b0d499 52 16 death death NN cord-354133-11b0d499 52 17 or or CC cord-354133-11b0d499 52 18 recovery recovery NN cord-354133-11b0d499 52 19 . . . cord-354133-11b0d499 53 1 However however RB cord-354133-11b0d499 53 2 , , , cord-354133-11b0d499 53 3 the the DT cord-354133-11b0d499 53 4 closeness closeness NN cord-354133-11b0d499 53 5 of of IN cord-354133-11b0d499 53 6 the the DT cord-354133-11b0d499 53 7 match match NN cord-354133-11b0d499 53 8 reflects reflect VBZ cord-354133-11b0d499 53 9 a a DT cord-354133-11b0d499 53 10 much much RB cord-354133-11b0d499 53 11 simpler simple JJR cord-354133-11b0d499 53 12 apparent apparent JJ cord-354133-11b0d499 53 13 relationship relationship NN cord-354133-11b0d499 53 14 than than IN cord-354133-11b0d499 53 15 that that DT cord-354133-11b0d499 53 16 suggested suggest VBD cord-354133-11b0d499 53 17 or or CC cord-354133-11b0d499 53 18 assumed assume VBN cord-354133-11b0d499 53 19 by by IN cord-354133-11b0d499 53 20 conventional conventional JJ cord-354133-11b0d499 53 21 analyses analysis NNS cord-354133-11b0d499 53 22 , , , cord-354133-11b0d499 53 23 which which WDT cord-354133-11b0d499 53 24 relate relate VBP cord-354133-11b0d499 53 25 deaths death NNS cord-354133-11b0d499 53 26 and and CC cord-354133-11b0d499 53 27 cases case NNS cord-354133-11b0d499 53 28 using use VBG cord-354133-11b0d499 53 29 statistical statistical JJ cord-354133-11b0d499 53 30 parametric parametric JJ cord-354133-11b0d499 53 31 models model NNS cord-354133-11b0d499 53 32 that that WDT cord-354133-11b0d499 53 33 incorporate incorporate VBP cord-354133-11b0d499 53 34 a a DT cord-354133-11b0d499 53 35 broad broad JJ cord-354133-11b0d499 53 36 distribution distribution NN cord-354133-11b0d499 53 37 of of IN cord-354133-11b0d499 53 38 expected expect VBN cord-354133-11b0d499 53 39 times time NNS cord-354133-11b0d499 53 40 between between IN cord-354133-11b0d499 53 41 diagnosis diagnosis NN cord-354133-11b0d499 53 42 ( ( -LRB- cord-354133-11b0d499 53 43 or or CC cord-354133-11b0d499 53 44 onset onset NN cord-354133-11b0d499 53 45 ) ) -RRB- cord-354133-11b0d499 53 46 and and CC cord-354133-11b0d499 53 47 death death NN cord-354133-11b0d499 53 48 , , , cord-354133-11b0d499 53 49 usually usually RB cord-354133-11b0d499 53 50 generated generate VBN cord-354133-11b0d499 53 51 from from IN cord-354133-11b0d499 53 52 case case NN cord-354133-11b0d499 53 53 study study NN cord-354133-11b0d499 53 54 data datum NNS cord-354133-11b0d499 53 55 ( ( -LRB- cord-354133-11b0d499 53 56 e.g. e.g. NN cord-354133-11b0d499 53 57 [ [ -LRB- cord-354133-11b0d499 53 58 15 15 CD cord-354133-11b0d499 53 59 ] ] -RRB- cord-354133-11b0d499 53 60 ) ) -RRB- cord-354133-11b0d499 53 61 . . . cord-354133-11b0d499 54 1 This this DT cord-354133-11b0d499 54 2 observation observation NN cord-354133-11b0d499 54 3 suggests suggest VBZ cord-354133-11b0d499 54 4 that that IN cord-354133-11b0d499 54 5 there there EX cord-354133-11b0d499 54 6 are be VBP cord-354133-11b0d499 54 7 two two CD cord-354133-11b0d499 54 8 parameters parameter NNS cord-354133-11b0d499 54 9 of of IN cord-354133-11b0d499 54 10 interest interest NN cord-354133-11b0d499 54 11 : : : cord-354133-11b0d499 54 12 the the DT cord-354133-11b0d499 54 13 number number NN cord-354133-11b0d499 54 14 of of IN cord-354133-11b0d499 54 15 days day NNS cord-354133-11b0d499 54 16 separating separate VBG cord-354133-11b0d499 54 17 the the DT cord-354133-11b0d499 54 18 case case NN cord-354133-11b0d499 54 19 and and CC cord-354133-11b0d499 54 20 death death NN cord-354133-11b0d499 54 21 distributions distribution NNS cord-354133-11b0d499 54 22 ( ( -LRB- cord-354133-11b0d499 54 23 called call VBN cord-354133-11b0d499 54 24 the the DT cord-354133-11b0d499 54 25 delay delay NN cord-354133-11b0d499 54 26 time time NN cord-354133-11b0d499 54 27 or or CC cord-354133-11b0d499 54 28 ! ! . cord-354133-11b0d499 54 29 ) ) -RRB- cord-354133-11b0d499 54 30 , , , cord-354133-11b0d499 54 31 and and CC cord-354133-11b0d499 54 32 the the DT cord-354133-11b0d499 54 33 scaling scale VBG cord-354133-11b0d499 54 34 factor factor NN cord-354133-11b0d499 54 35 between between IN cord-354133-11b0d499 54 36 the the DT cord-354133-11b0d499 54 37 time time NN cord-354133-11b0d499 54 38 - - HYPH cord-354133-11b0d499 54 39 shifted shift VBN cord-354133-11b0d499 54 40 case case NN cord-354133-11b0d499 54 41 data datum NNS cord-354133-11b0d499 54 42 and and CC cord-354133-11b0d499 54 43 the the DT cord-354133-11b0d499 54 44 death death NN cord-354133-11b0d499 54 45 data datum NNS cord-354133-11b0d499 54 46 , , , cord-354133-11b0d499 54 47 . . . cord-354133-11b0d499 55 1 For for IN cord-354133-11b0d499 55 2 the the DT cord-354133-11b0d499 55 3 optimal optimal JJ cord-354133-11b0d499 55 4 value value NN cord-354133-11b0d499 55 5 of of IN cord-354133-11b0d499 55 6 ! ! . cord-354133-11b0d499 56 1 , , , cord-354133-11b0d499 56 2 there there EX cord-354133-11b0d499 56 3 is be VBZ cord-354133-11b0d499 56 4 a a DT cord-354133-11b0d499 56 5 simple simple JJ cord-354133-11b0d499 56 6 linear linear JJ cord-354133-11b0d499 56 7 relationship relationship NN cord-354133-11b0d499 56 8 between between IN cord-354133-11b0d499 56 9 cumulative cumulative JJ cord-354133-11b0d499 56 10 number number NN cord-354133-11b0d499 56 11 of of IN cord-354133-11b0d499 56 12 deaths death NNS cord-354133-11b0d499 56 13 at at IN cord-354133-11b0d499 56 14 time time NN cord-354133-11b0d499 56 15 , , , cord-354133-11b0d499 56 16 ( ( -LRB- cord-354133-11b0d499 56 17 ) ) -RRB- cord-354133-11b0d499 56 18 , , , cord-354133-11b0d499 56 19 and and CC cord-354133-11b0d499 56 20 cumulative cumulative JJ cord-354133-11b0d499 56 21 number number NN cord-354133-11b0d499 56 22 of of IN cord-354133-11b0d499 56 23 cases case NNS cord-354133-11b0d499 56 24 at at IN cord-354133-11b0d499 56 25 time time NN cord-354133-11b0d499 56 26 − − NNP cord-354133-11b0d499 56 27 ! ! . cord-354133-11b0d499 56 28 , , , cord-354133-11b0d499 56 29 ( ( -LRB- cord-354133-11b0d499 56 30 − − NNP cord-354133-11b0d499 56 31 ! ! . cord-354133-11b0d499 56 32 ) ) -RRB- cord-354133-11b0d499 56 33 , , , cord-354133-11b0d499 56 34 with with IN cord-354133-11b0d499 56 35 gradient gradient NN cord-354133-11b0d499 56 36 : : : cord-354133-11b0d499 57 1 To to TO cord-354133-11b0d499 57 2 find find VB cord-354133-11b0d499 57 3 the the DT cord-354133-11b0d499 57 4 optimal optimal JJ cord-354133-11b0d499 57 5 value value NN cord-354133-11b0d499 57 6 for for IN cord-354133-11b0d499 57 7 ! ! . cord-354133-11b0d499 58 1 , , , cord-354133-11b0d499 58 2 we -PRON- PRP cord-354133-11b0d499 58 3 test test VBP cord-354133-11b0d499 58 4 integer integ JJR cord-354133-11b0d499 58 5 values value NNS cord-354133-11b0d499 58 6 from from IN cord-354133-11b0d499 58 7 zero zero CD cord-354133-11b0d499 58 8 to to IN cord-354133-11b0d499 58 9 25 25 CD cord-354133-11b0d499 58 10 days day NNS cord-354133-11b0d499 58 11 . . . cord-354133-11b0d499 59 1 For for IN cord-354133-11b0d499 59 2 each each DT cord-354133-11b0d499 59 3 value value NN cord-354133-11b0d499 59 4 of of IN cord-354133-11b0d499 59 5 ! ! . cord-354133-11b0d499 59 6 , , , cord-354133-11b0d499 59 7 we -PRON- PRP cord-354133-11b0d499 59 8 plot plot VBP cord-354133-11b0d499 59 9 ( ( -LRB- cord-354133-11b0d499 59 10 ) ) -RRB- cord-354133-11b0d499 59 11 as as IN cord-354133-11b0d499 59 12 a a DT cord-354133-11b0d499 59 13 function function NN cord-354133-11b0d499 59 14 of of IN cord-354133-11b0d499 59 15 ( ( -LRB- cord-354133-11b0d499 59 16 − − NNP cord-354133-11b0d499 59 17 ! ! . cord-354133-11b0d499 59 18 ) ) -RRB- cord-354133-11b0d499 59 19 ( ( -LRB- cord-354133-11b0d499 59 20 for for IN cord-354133-11b0d499 59 21 all all DT cord-354133-11b0d499 59 22 ) ) -RRB- cord-354133-11b0d499 59 23 and and CC cord-354133-11b0d499 59 24 perform perform VB cord-354133-11b0d499 59 25 a a DT cord-354133-11b0d499 59 26 linear linear JJ cord-354133-11b0d499 59 27 regression regression NN cord-354133-11b0d499 59 28 using use VBG cord-354133-11b0d499 59 29 Matlab Matlab NNP cord-354133-11b0d499 59 30 . . . cord-354133-11b0d499 60 1 The the DT cord-354133-11b0d499 60 2 value value NN cord-354133-11b0d499 60 3 of of IN cord-354133-11b0d499 60 4 ! ! . cord-354133-11b0d499 60 5 is be VBZ cord-354133-11b0d499 60 6 chosen choose VBN cord-354133-11b0d499 60 7 on on IN cord-354133-11b0d499 60 8 the the DT cord-354133-11b0d499 60 9 basis basis NN cord-354133-11b0d499 60 10 of of IN cord-354133-11b0d499 60 11 the the DT cord-354133-11b0d499 60 12 lowest low JJS cord-354133-11b0d499 60 13 root root NN cord-354133-11b0d499 60 14 - - HYPH cord-354133-11b0d499 60 15 mean mean NN cord-354133-11b0d499 60 16 - - HYPH cord-354133-11b0d499 60 17 squared squared JJ cord-354133-11b0d499 60 18 error error NN cord-354133-11b0d499 60 19 in in IN cord-354133-11b0d499 60 20 the the DT cord-354133-11b0d499 60 21 linear linear JJ cord-354133-11b0d499 60 22 regression regression NN cord-354133-11b0d499 60 23 analysis analysis NN cord-354133-11b0d499 60 24 and and CC cord-354133-11b0d499 60 25 the the DT cord-354133-11b0d499 60 26 value value NN cord-354133-11b0d499 60 27 of of IN cord-354133-11b0d499 60 28 is be VBZ cord-354133-11b0d499 60 29 the the DT cord-354133-11b0d499 60 30 gradient gradient NN cord-354133-11b0d499 60 31 of of IN cord-354133-11b0d499 60 32 the the DT cord-354133-11b0d499 60 33 corresponding corresponding JJ cord-354133-11b0d499 60 34 line line NN cord-354133-11b0d499 60 35 . . . cord-354133-11b0d499 61 1 is be VBZ cord-354133-11b0d499 61 2 the the DT cord-354133-11b0d499 61 3 author author NN cord-354133-11b0d499 61 4 / / SYM cord-354133-11b0d499 61 5 funder funder NN cord-354133-11b0d499 61 6 , , , cord-354133-11b0d499 61 7 who who WP cord-354133-11b0d499 61 8 has have VBZ cord-354133-11b0d499 61 9 granted grant VBN cord-354133-11b0d499 61 10 medRxiv medRxiv NNS cord-354133-11b0d499 61 11 a a DT cord-354133-11b0d499 61 12 license license NN cord-354133-11b0d499 61 13 to to TO cord-354133-11b0d499 61 14 display display VB cord-354133-11b0d499 61 15 the the DT cord-354133-11b0d499 61 16 preprint preprint NN cord-354133-11b0d499 61 17 in in IN cord-354133-11b0d499 61 18 ( ( -LRB- cord-354133-11b0d499 61 19 which which WDT cord-354133-11b0d499 61 20 was be VBD cord-354133-11b0d499 61 21 not not RB cord-354133-11b0d499 61 22 certified certify VBN cord-354133-11b0d499 61 23 by by IN cord-354133-11b0d499 61 24 peer peer NN cord-354133-11b0d499 61 25 review review NN cord-354133-11b0d499 61 26 ) ) -RRB- cord-354133-11b0d499 61 27 preprint preprint NN cord-354133-11b0d499 62 1 The the DT cord-354133-11b0d499 62 2 copyright copyright NN cord-354133-11b0d499 62 3 holder holder NN cord-354133-11b0d499 62 4 for for IN cord-354133-11b0d499 62 5 this this DT cord-354133-11b0d499 62 6 this this DT cord-354133-11b0d499 62 7 version version NN cord-354133-11b0d499 62 8 posted post VBD cord-354133-11b0d499 62 9 October October NNP cord-354133-11b0d499 62 10 27 27 CD cord-354133-11b0d499 62 11 , , , cord-354133-11b0d499 62 12 2020 2020 CD cord-354133-11b0d499 62 13 . . . cord-354133-11b0d499 63 1 ; ; : cord-354133-11b0d499 63 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 63 3 doi doi NN cord-354133-11b0d499 63 4 : : : cord-354133-11b0d499 64 1 medRxiv medRxiv NNS cord-354133-11b0d499 64 2 preprint preprint NN cord-354133-11b0d499 64 3 respectively respectively RB cord-354133-11b0d499 64 4 ) ) -RRB- cord-354133-11b0d499 64 5 , , , cord-354133-11b0d499 64 6 using use VBG cord-354133-11b0d499 64 7 a a DT cord-354133-11b0d499 64 8 delay delay NN cord-354133-11b0d499 64 9 time time NN cord-354133-11b0d499 64 10 of of IN cord-354133-11b0d499 64 11 four four CD cord-354133-11b0d499 64 12 days day NNS cord-354133-11b0d499 64 13 and and CC cord-354133-11b0d499 64 14 a a DT cord-354133-11b0d499 64 15 linear linear JJ cord-354133-11b0d499 64 16 scaling scaling NN cord-354133-11b0d499 64 17 factor factor NN cord-354133-11b0d499 64 18 of of IN cord-354133-11b0d499 64 19 0.144 0.144 CD cord-354133-11b0d499 64 20 . . . cord-354133-11b0d499 65 1 What what WP cord-354133-11b0d499 65 2 do do VBP cord-354133-11b0d499 65 3 these these DT cord-354133-11b0d499 65 4 parameters parameter NNS cord-354133-11b0d499 65 5 represent represent VB cord-354133-11b0d499 65 6 ? ? . cord-354133-11b0d499 66 1 The the DT cord-354133-11b0d499 66 2 delay delay NN cord-354133-11b0d499 66 3 time time NN cord-354133-11b0d499 66 4 is be VBZ cord-354133-11b0d499 66 5 presumably presumably RB cord-354133-11b0d499 66 6 a a DT cord-354133-11b0d499 66 7 measure measure NN cord-354133-11b0d499 66 8 of of IN cord-354133-11b0d499 66 9 the the DT cord-354133-11b0d499 66 10 delay delay NN cord-354133-11b0d499 66 11 between between IN cord-354133-11b0d499 66 12 reporting reporting NN cord-354133-11b0d499 66 13 of of IN cord-354133-11b0d499 66 14 confirmed confirm VBN cord-354133-11b0d499 66 15 cases case NNS cord-354133-11b0d499 66 16 and and CC cord-354133-11b0d499 66 17 reporting reporting NN cord-354133-11b0d499 66 18 of of IN cord-354133-11b0d499 66 19 COVID-19-related covid-19-related JJ cord-354133-11b0d499 66 20 deaths death NNS cord-354133-11b0d499 66 21 . . . cord-354133-11b0d499 67 1 While while IN cord-354133-11b0d499 67 2 four four CD cord-354133-11b0d499 67 3 days day NNS cord-354133-11b0d499 67 4 seems seem VBZ cord-354133-11b0d499 67 5 very very RB cord-354133-11b0d499 67 6 short short JJ cord-354133-11b0d499 67 7 compared compare VBN cord-354133-11b0d499 67 8 to to IN cord-354133-11b0d499 67 9 current current JJ cord-354133-11b0d499 67 10 estimates estimate NNS cord-354133-11b0d499 67 11 of of IN cord-354133-11b0d499 67 12 the the DT cord-354133-11b0d499 67 13 mean mean JJ cord-354133-11b0d499 67 14 delay delay NN cord-354133-11b0d499 67 15 between between IN cord-354133-11b0d499 67 16 onset onset NN cord-354133-11b0d499 67 17 of of IN cord-354133-11b0d499 67 18 COVID-19 covid-19 JJ cord-354133-11b0d499 67 19 symptoms symptom NNS cord-354133-11b0d499 67 20 and and CC cord-354133-11b0d499 67 21 death death NN cord-354133-11b0d499 67 22 ( ( -LRB- cord-354133-11b0d499 67 23 or or CC cord-354133-11b0d499 67 24 even even RB cord-354133-11b0d499 67 25 between between IN cord-354133-11b0d499 67 26 hospitalisation hospitalisation NN cord-354133-11b0d499 67 27 and and CC cord-354133-11b0d499 67 28 death death NN cord-354133-11b0d499 67 29 ) ) -RRB- cord-354133-11b0d499 67 30 , , , cord-354133-11b0d499 67 31 which which WDT cord-354133-11b0d499 67 32 is be VBZ cord-354133-11b0d499 67 33 around around RB cord-354133-11b0d499 67 34 12 12 CD cord-354133-11b0d499 67 35 - - SYM cord-354133-11b0d499 67 36 22 22 CD cord-354133-11b0d499 67 37 days day NNS cord-354133-11b0d499 67 38 with with IN cord-354133-11b0d499 67 39 a a DT cord-354133-11b0d499 67 40 large large JJ cord-354133-11b0d499 67 41 variance variance NN cord-354133-11b0d499 67 42 [ [ -LRB- cord-354133-11b0d499 67 43 2 2 CD cord-354133-11b0d499 67 44 , , , cord-354133-11b0d499 67 45 5 5 CD cord-354133-11b0d499 67 46 , , , cord-354133-11b0d499 67 47 7 7 CD cord-354133-11b0d499 67 48 , , , cord-354133-11b0d499 67 49 10 10 CD cord-354133-11b0d499 67 50 , , , cord-354133-11b0d499 67 51 16 16 CD cord-354133-11b0d499 67 52 ] ] -RRB- cord-354133-11b0d499 67 53 , , , cord-354133-11b0d499 67 54 it -PRON- PRP cord-354133-11b0d499 67 55 is be VBZ cord-354133-11b0d499 67 56 possible possible JJ cord-354133-11b0d499 67 57 to to TO cord-354133-11b0d499 67 58 rationalise rationalise VB cord-354133-11b0d499 67 59 the the DT cord-354133-11b0d499 67 60 shorter short JJR cord-354133-11b0d499 67 61 apparent apparent JJ cord-354133-11b0d499 67 62 delay delay NN cord-354133-11b0d499 67 63 on on IN cord-354133-11b0d499 67 64 the the DT cord-354133-11b0d499 67 65 basis basis NN cord-354133-11b0d499 67 66 of of IN cord-354133-11b0d499 67 67 delays delay NNS cord-354133-11b0d499 67 68 in in IN cord-354133-11b0d499 67 69 testing testing NN cord-354133-11b0d499 67 70 , , , cord-354133-11b0d499 67 71 diagnosis diagnosis NN cord-354133-11b0d499 67 72 and and CC cord-354133-11b0d499 67 73 reporting reporting NN cord-354133-11b0d499 67 74 of of IN cord-354133-11b0d499 67 75 the the DT cord-354133-11b0d499 67 76 disease disease NN cord-354133-11b0d499 67 77 , , , cord-354133-11b0d499 67 78 particularly particularly RB cord-354133-11b0d499 67 79 in in IN cord-354133-11b0d499 67 80 countries country NNS cord-354133-11b0d499 67 81 where where WRB cord-354133-11b0d499 67 82 the the DT cord-354133-11b0d499 67 83 outbreak outbreak NN cord-354133-11b0d499 67 84 is be VBZ cord-354133-11b0d499 67 85 severe severe JJ cord-354133-11b0d499 67 86 . . . cord-354133-11b0d499 68 1 For for IN cord-354133-11b0d499 68 2 example example NN cord-354133-11b0d499 68 3 , , , cord-354133-11b0d499 68 4 in in IN cord-354133-11b0d499 68 5 Italy Italy NNP cord-354133-11b0d499 68 6 from from IN cord-354133-11b0d499 68 7 late late JJ cord-354133-11b0d499 68 8 February February NNP cord-354133-11b0d499 68 9 , , , cord-354133-11b0d499 68 10 testing testing NN cord-354133-11b0d499 68 11 was be VBD cord-354133-11b0d499 68 12 prioritized prioritize VBN cord-354133-11b0d499 68 13 for for IN cord-354133-11b0d499 68 14 " " `` cord-354133-11b0d499 68 15 patients patient NNS cord-354133-11b0d499 68 16 with with IN cord-354133-11b0d499 68 17 more more RBR cord-354133-11b0d499 68 18 severe severe JJ cord-354133-11b0d499 68 19 clinical clinical JJ cord-354133-11b0d499 68 20 symptoms symptom NNS cord-354133-11b0d499 68 21 who who WP cord-354133-11b0d499 68 22 were be VBD cord-354133-11b0d499 68 23 suspected suspect VBN cord-354133-11b0d499 68 24 of of IN cord-354133-11b0d499 68 25 having have VBG cord-354133-11b0d499 68 26 COVID-19 covid-19 VB cord-354133-11b0d499 68 27 and and CC cord-354133-11b0d499 68 28 required require VBN cord-354133-11b0d499 68 29 hospitalization hospitalization NN cord-354133-11b0d499 68 30 " " '' cord-354133-11b0d499 68 31 [ [ -LRB- cord-354133-11b0d499 68 32 17 17 CD cord-354133-11b0d499 68 33 ] ] -RRB- cord-354133-11b0d499 68 34 ; ; : cord-354133-11b0d499 68 35 a a DT cord-354133-11b0d499 68 36 subsequent subsequent JJ cord-354133-11b0d499 68 37 delay delay NN cord-354133-11b0d499 68 38 in in IN cord-354133-11b0d499 68 39 test test NN cord-354133-11b0d499 68 40 results result NNS cord-354133-11b0d499 68 41 could could MD cord-354133-11b0d499 68 42 account account VB cord-354133-11b0d499 68 43 for for IN cord-354133-11b0d499 68 44 the the DT cord-354133-11b0d499 68 45 rather rather RB cord-354133-11b0d499 68 46 short short JJ cord-354133-11b0d499 68 47 delay delay NN cord-354133-11b0d499 68 48 is be VBZ cord-354133-11b0d499 68 49 the the DT cord-354133-11b0d499 68 50 author author NN cord-354133-11b0d499 68 51 / / SYM cord-354133-11b0d499 68 52 funder funder NN cord-354133-11b0d499 68 53 , , , cord-354133-11b0d499 68 54 who who WP cord-354133-11b0d499 68 55 has have VBZ cord-354133-11b0d499 68 56 granted grant VBN cord-354133-11b0d499 68 57 medRxiv medRxiv NNS cord-354133-11b0d499 68 58 a a DT cord-354133-11b0d499 68 59 license license NN cord-354133-11b0d499 68 60 to to TO cord-354133-11b0d499 68 61 display display VB cord-354133-11b0d499 68 62 the the DT cord-354133-11b0d499 68 63 preprint preprint NN cord-354133-11b0d499 68 64 in in IN cord-354133-11b0d499 68 65 ( ( -LRB- cord-354133-11b0d499 68 66 which which WDT cord-354133-11b0d499 68 67 was be VBD cord-354133-11b0d499 68 68 not not RB cord-354133-11b0d499 68 69 certified certify VBN cord-354133-11b0d499 68 70 by by IN cord-354133-11b0d499 68 71 peer peer NN cord-354133-11b0d499 68 72 review review NN cord-354133-11b0d499 68 73 ) ) -RRB- cord-354133-11b0d499 68 74 preprint preprint NN cord-354133-11b0d499 69 1 The the DT cord-354133-11b0d499 69 2 copyright copyright NN cord-354133-11b0d499 69 3 holder holder NN cord-354133-11b0d499 69 4 for for IN cord-354133-11b0d499 69 5 this this DT cord-354133-11b0d499 69 6 this this DT cord-354133-11b0d499 69 7 version version NN cord-354133-11b0d499 69 8 posted post VBD cord-354133-11b0d499 69 9 October October NNP cord-354133-11b0d499 69 10 27 27 CD cord-354133-11b0d499 69 11 , , , cord-354133-11b0d499 69 12 2020 2020 CD cord-354133-11b0d499 69 13 . . . cord-354133-11b0d499 70 1 between between IN cord-354133-11b0d499 70 2 reported reported JJ cord-354133-11b0d499 70 3 diagnosis diagnosis NN cord-354133-11b0d499 70 4 and and CC cord-354133-11b0d499 70 5 death death NN cord-354133-11b0d499 70 6 . . . cord-354133-11b0d499 71 1 This this DT cord-354133-11b0d499 71 2 shows show VBZ cord-354133-11b0d499 71 3 the the DT cord-354133-11b0d499 71 4 inherent inherent JJ cord-354133-11b0d499 71 5 danger danger NN cord-354133-11b0d499 71 6 in in IN cord-354133-11b0d499 71 7 analysing analyse VBG cord-354133-11b0d499 71 8 such such JJ cord-354133-11b0d499 71 9 datasets dataset NNS cord-354133-11b0d499 71 10 using use VBG cord-354133-11b0d499 71 11 time time NN cord-354133-11b0d499 71 12 - - HYPH cord-354133-11b0d499 71 13 delay delay NN cord-354133-11b0d499 71 14 distributions distribution NNS cord-354133-11b0d499 71 15 from from IN cord-354133-11b0d499 71 16 specific specific JJ cord-354133-11b0d499 71 17 case case NN cord-354133-11b0d499 71 18 data datum NNS cord-354133-11b0d499 71 19 ( ( -LRB- cord-354133-11b0d499 71 20 which which WDT cord-354133-11b0d499 71 21 presumes presume VBZ cord-354133-11b0d499 71 22 a a DT cord-354133-11b0d499 71 23 much much RB cord-354133-11b0d499 71 24 longer long JJR cord-354133-11b0d499 71 25 delay delay NN cord-354133-11b0d499 71 26 time time NN cord-354133-11b0d499 71 27 ) ) -RRB- cord-354133-11b0d499 71 28 . . . cord-354133-11b0d499 72 1 Moreover moreover RB cord-354133-11b0d499 72 2 , , , cord-354133-11b0d499 72 3 the the DT cord-354133-11b0d499 72 4 delay delay NN cord-354133-11b0d499 72 5 time time NN cord-354133-11b0d499 72 6 may may MD cord-354133-11b0d499 72 7 provide provide VB cord-354133-11b0d499 72 8 some some DT cord-354133-11b0d499 72 9 useful useful JJ cord-354133-11b0d499 72 10 information information NN cord-354133-11b0d499 72 11 about about IN cord-354133-11b0d499 72 12 relative relative JJ cord-354133-11b0d499 72 13 conditions condition NNS cord-354133-11b0d499 72 14 in in IN cord-354133-11b0d499 72 15 various various JJ cord-354133-11b0d499 72 16 countries country NNS cord-354133-11b0d499 72 17 . . . cord-354133-11b0d499 73 1 is be VBZ cord-354133-11b0d499 73 2 the the DT cord-354133-11b0d499 73 3 author author NN cord-354133-11b0d499 73 4 / / SYM cord-354133-11b0d499 73 5 funder funder NN cord-354133-11b0d499 73 6 , , , cord-354133-11b0d499 73 7 who who WP cord-354133-11b0d499 73 8 has have VBZ cord-354133-11b0d499 73 9 granted grant VBN cord-354133-11b0d499 73 10 medRxiv medRxiv NNS cord-354133-11b0d499 73 11 a a DT cord-354133-11b0d499 73 12 license license NN cord-354133-11b0d499 73 13 to to TO cord-354133-11b0d499 73 14 display display VB cord-354133-11b0d499 73 15 the the DT cord-354133-11b0d499 73 16 preprint preprint NN cord-354133-11b0d499 73 17 in in IN cord-354133-11b0d499 73 18 ( ( -LRB- cord-354133-11b0d499 73 19 which which WDT cord-354133-11b0d499 73 20 was be VBD cord-354133-11b0d499 73 21 not not RB cord-354133-11b0d499 73 22 certified certify VBN cord-354133-11b0d499 73 23 by by IN cord-354133-11b0d499 73 24 peer peer NN cord-354133-11b0d499 73 25 review review NN cord-354133-11b0d499 73 26 ) ) -RRB- cord-354133-11b0d499 73 27 preprint preprint NN cord-354133-11b0d499 74 1 The the DT cord-354133-11b0d499 74 2 copyright copyright NN cord-354133-11b0d499 74 3 holder holder NN cord-354133-11b0d499 74 4 for for IN cord-354133-11b0d499 74 5 this this DT cord-354133-11b0d499 74 6 this this DT cord-354133-11b0d499 74 7 version version NN cord-354133-11b0d499 74 8 posted post VBD cord-354133-11b0d499 74 9 October October NNP cord-354133-11b0d499 74 10 27 27 CD cord-354133-11b0d499 74 11 , , , cord-354133-11b0d499 74 12 2020 2020 CD cord-354133-11b0d499 74 13 . . . cord-354133-11b0d499 75 1 ; ; : cord-354133-11b0d499 75 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 75 3 doi doi NN cord-354133-11b0d499 75 4 : : : cord-354133-11b0d499 76 1 medRxiv medRxiv NNP cord-354133-11b0d499 76 2 preprint preprint NN cord-354133-11b0d499 76 3 7 7 CD cord-354133-11b0d499 76 4 Using use VBG cord-354133-11b0d499 76 5 a a DT cord-354133-11b0d499 76 6 time time NN cord-354133-11b0d499 76 7 delay delay NN cord-354133-11b0d499 76 8 of of IN cord-354133-11b0d499 76 9 four four CD cord-354133-11b0d499 76 10 days day NNS cord-354133-11b0d499 76 11 in in IN cord-354133-11b0d499 76 12 Italy Italy NNP cord-354133-11b0d499 76 13 , , , cord-354133-11b0d499 76 14 the the DT cord-354133-11b0d499 76 15 scaling scale VBG cord-354133-11b0d499 76 16 factor factor NN cord-354133-11b0d499 76 17 of of IN cord-354133-11b0d499 76 18 0.144 0.144 CD cord-354133-11b0d499 76 19 represents represent VBZ cord-354133-11b0d499 76 20 the the DT cord-354133-11b0d499 76 21 ratio ratio NN cord-354133-11b0d499 76 22 of of IN cord-354133-11b0d499 76 23 deaths death NNS cord-354133-11b0d499 76 24 to to IN cord-354133-11b0d499 76 25 cases case NNS cord-354133-11b0d499 76 26 , , , cord-354133-11b0d499 76 27 or or CC cord-354133-11b0d499 76 28 in in IN cord-354133-11b0d499 76 29 other other JJ cord-354133-11b0d499 76 30 words word NNS cord-354133-11b0d499 76 31 , , , cord-354133-11b0d499 76 32 an an DT cord-354133-11b0d499 76 33 estimate estimate NN cord-354133-11b0d499 76 34 for for IN cord-354133-11b0d499 76 35 the the DT cord-354133-11b0d499 76 36 case case NN cord-354133-11b0d499 76 37 fatality fatality NN cord-354133-11b0d499 76 38 ratio ratio NN cord-354133-11b0d499 76 39 , , , cord-354133-11b0d499 76 40 converging converge VBG cord-354133-11b0d499 76 41 towards towards IN cord-354133-11b0d499 76 42 the the DT cord-354133-11b0d499 76 43 crude crude JJ cord-354133-11b0d499 76 44 CFR CFR NNP cord-354133-11b0d499 76 45 with with IN cord-354133-11b0d499 76 46 time time NN cord-354133-11b0d499 76 47 . . . cord-354133-11b0d499 77 1 The the DT cord-354133-11b0d499 77 2 calculated calculate VBN cord-354133-11b0d499 77 3 CFR CFR NNP cord-354133-11b0d499 77 4 of of IN cord-354133-11b0d499 77 5 14.4 14.4 CD cord-354133-11b0d499 77 6 % % NN cord-354133-11b0d499 77 7 is be VBZ cord-354133-11b0d499 77 8 almost almost RB cord-354133-11b0d499 77 9 identical identical JJ cord-354133-11b0d499 77 10 to to IN cord-354133-11b0d499 77 11 the the DT cord-354133-11b0d499 77 12 crude crude JJ cord-354133-11b0d499 77 13 CFR CFR NNP cord-354133-11b0d499 77 14 of of IN cord-354133-11b0d499 77 15 14.5 14.5 CD cord-354133-11b0d499 77 16 % % NN cord-354133-11b0d499 77 17 at at IN cord-354133-11b0d499 77 18 the the DT cord-354133-11b0d499 77 19 end end NN cord-354133-11b0d499 77 20 of of IN cord-354133-11b0d499 77 21 June June NNP cord-354133-11b0d499 77 22 , , , cord-354133-11b0d499 77 23 which which WDT cord-354133-11b0d499 77 24 is be VBZ cord-354133-11b0d499 77 25 a a DT cord-354133-11b0d499 77 26 good good JJ cord-354133-11b0d499 77 27 estimate estimate NN cord-354133-11b0d499 77 28 for for IN cord-354133-11b0d499 77 29 the the DT cord-354133-11b0d499 77 30 " " `` cord-354133-11b0d499 77 31 true true JJ cord-354133-11b0d499 77 32 " " '' cord-354133-11b0d499 77 33 CFR CFR NNP cord-354133-11b0d499 77 34 at at IN cord-354133-11b0d499 77 35 the the DT cord-354133-11b0d499 77 36 end end NN cord-354133-11b0d499 77 37 of of IN cord-354133-11b0d499 77 38 the the DT cord-354133-11b0d499 77 39 outbreak outbreak NN cord-354133-11b0d499 77 40 . . . cord-354133-11b0d499 78 1 An an DT cord-354133-11b0d499 78 2 interesting interesting JJ cord-354133-11b0d499 78 3 question question NN cord-354133-11b0d499 78 4 is be VBZ cord-354133-11b0d499 78 5 , , , cord-354133-11b0d499 78 6 at at IN cord-354133-11b0d499 78 7 what what WDT cord-354133-11b0d499 78 8 point point NN cord-354133-11b0d499 78 9 in in IN cord-354133-11b0d499 78 10 the the DT cord-354133-11b0d499 78 11 outbreak outbreak NN cord-354133-11b0d499 78 12 does do VBZ cord-354133-11b0d499 78 13 the the DT cord-354133-11b0d499 78 14 CFR CFR NNP cord-354133-11b0d499 78 15 calculated calculate VBN cord-354133-11b0d499 78 16 using use VBG cord-354133-11b0d499 78 17 the the DT cord-354133-11b0d499 78 18 TSD TSD NNP cord-354133-11b0d499 78 19 analysis analysis NN cord-354133-11b0d499 78 20 give give VBP cord-354133-11b0d499 78 21 a a DT cord-354133-11b0d499 78 22 good good JJ cord-354133-11b0d499 78 23 approximation approximation NN cord-354133-11b0d499 78 24 to to IN cord-354133-11b0d499 78 25 the the DT cord-354133-11b0d499 78 26 final final JJ cord-354133-11b0d499 78 27 value value NN cord-354133-11b0d499 78 28 ? ? . cord-354133-11b0d499 79 1 This this DT cord-354133-11b0d499 79 2 is be VBZ cord-354133-11b0d499 79 3 important important JJ cord-354133-11b0d499 79 4 because because IN cord-354133-11b0d499 79 5 early early JJ cord-354133-11b0d499 79 6 estimates estimate NNS cord-354133-11b0d499 79 7 of of IN cord-354133-11b0d499 79 8 CFR CFR NNP cord-354133-11b0d499 79 9 are be VBP cord-354133-11b0d499 79 10 vital vital JJ cord-354133-11b0d499 79 11 for for IN cord-354133-11b0d499 79 12 informing inform VBG cord-354133-11b0d499 79 13 public public JJ cord-354133-11b0d499 79 14 health health NN cord-354133-11b0d499 79 15 decisions decision NNS cord-354133-11b0d499 79 16 . . . cord-354133-11b0d499 80 1 Figure figure NN cord-354133-11b0d499 80 2 3 3 CD cord-354133-11b0d499 80 3 shows show VBZ cord-354133-11b0d499 80 4 the the DT cord-354133-11b0d499 80 5 CFR CFR NNP cord-354133-11b0d499 80 6 calculated calculate VBN cord-354133-11b0d499 80 7 at at IN cord-354133-11b0d499 80 8 various various JJ cord-354133-11b0d499 80 9 stages stage NNS cord-354133-11b0d499 80 10 of of IN cord-354133-11b0d499 80 11 the the DT cord-354133-11b0d499 80 12 outbreak outbreak NN cord-354133-11b0d499 80 13 using use VBG cord-354133-11b0d499 80 14 data datum NNS cord-354133-11b0d499 80 15 available available JJ cord-354133-11b0d499 80 16 to to IN cord-354133-11b0d499 80 17 that that DT cord-354133-11b0d499 80 18 point point NN cord-354133-11b0d499 80 19 . . . cord-354133-11b0d499 81 1 Errors error NNS cord-354133-11b0d499 81 2 represent represent VBP cord-354133-11b0d499 81 3 uncertainty uncertainty NN cord-354133-11b0d499 81 4 in in IN cord-354133-11b0d499 81 5 the the DT cord-354133-11b0d499 81 6 linear linear JJ cord-354133-11b0d499 81 7 regression regression NN cord-354133-11b0d499 81 8 as as RB cord-354133-11b0d499 81 9 well well RB cord-354133-11b0d499 81 10 as as IN cord-354133-11b0d499 81 11 in in RB cord-354133-11b0d499 81 12 ! ! . cord-354133-11b0d499 81 13 . . . cord-354133-11b0d499 82 1 The the DT cord-354133-11b0d499 82 2 earliest early JJS cord-354133-11b0d499 82 3 data datum NNS cord-354133-11b0d499 82 4 predict predict VBP cord-354133-11b0d499 82 5 a a DT cord-354133-11b0d499 82 6 longer long JJR cord-354133-11b0d499 82 7 delay delay NN cord-354133-11b0d499 82 8 time time NN cord-354133-11b0d499 82 9 , , , cord-354133-11b0d499 82 10 which which WDT cord-354133-11b0d499 82 11 results result VBZ cord-354133-11b0d499 82 12 in in IN cord-354133-11b0d499 82 13 a a DT cord-354133-11b0d499 82 14 higher high JJR cord-354133-11b0d499 82 15 predicted predict VBN cord-354133-11b0d499 82 16 CFR CFR NNP cord-354133-11b0d499 82 17 ; ; : cord-354133-11b0d499 82 18 once once RB cord-354133-11b0d499 82 19 the the DT cord-354133-11b0d499 82 20 value value NN cord-354133-11b0d499 82 21 of of IN cord-354133-11b0d499 82 22 ! ! . cord-354133-11b0d499 82 23 has have VBZ cord-354133-11b0d499 82 24 stabilised stabilise VBN cord-354133-11b0d499 82 25 ( ( -LRB- cord-354133-11b0d499 82 26 from from IN cord-354133-11b0d499 82 27 26 26 CD cord-354133-11b0d499 82 28 March March NNP cord-354133-11b0d499 82 29 ) ) -RRB- cord-354133-11b0d499 82 30 , , , cord-354133-11b0d499 82 31 the the DT cord-354133-11b0d499 82 32 predicted predict VBN cord-354133-11b0d499 82 33 value value NN cord-354133-11b0d499 82 34 of of IN cord-354133-11b0d499 82 35 CFR CFR NNP cord-354133-11b0d499 82 36 is be VBZ cord-354133-11b0d499 82 37 also also RB cord-354133-11b0d499 82 38 very very RB cord-354133-11b0d499 82 39 stable stable JJ cord-354133-11b0d499 82 40 , , , cord-354133-11b0d499 82 41 and and CC cord-354133-11b0d499 82 42 also also RB cord-354133-11b0d499 82 43 remarkably remarkably RB cord-354133-11b0d499 82 44 accurate accurate JJ cord-354133-11b0d499 82 45 ( ( -LRB- cord-354133-11b0d499 82 46 14.4 14.4 CD cord-354133-11b0d499 82 47 % % NN cord-354133-11b0d499 82 48 ) ) -RRB- cord-354133-11b0d499 82 49 , , , cord-354133-11b0d499 82 50 compared compare VBN cord-354133-11b0d499 82 51 to to IN cord-354133-11b0d499 82 52 the the DT cord-354133-11b0d499 82 53 crude crude JJ cord-354133-11b0d499 82 54 value value NN cord-354133-11b0d499 82 55 of of IN cord-354133-11b0d499 82 56 10.3 10.3 CD cord-354133-11b0d499 82 57 % % NN cord-354133-11b0d499 82 58 at at IN cord-354133-11b0d499 82 59 that that DT cord-354133-11b0d499 82 60 time time NN cord-354133-11b0d499 82 61 . . . cord-354133-11b0d499 83 1 Even even RB cord-354133-11b0d499 83 2 a a DT cord-354133-11b0d499 83 3 week week NN cord-354133-11b0d499 83 4 earlier early RBR cord-354133-11b0d499 83 5 , , , cord-354133-11b0d499 83 6 the the DT cord-354133-11b0d499 83 7 calculated calculate VBN cord-354133-11b0d499 83 8 CFR CFR NNP cord-354133-11b0d499 83 9 of of IN cord-354133-11b0d499 83 10 16.6 16.6 CD cord-354133-11b0d499 83 11 % % NN cord-354133-11b0d499 83 12 is be VBZ cord-354133-11b0d499 83 13 a a DT cord-354133-11b0d499 83 14 better well JJR cord-354133-11b0d499 83 15 estimate estimate NN cord-354133-11b0d499 83 16 than than IN cord-354133-11b0d499 83 17 the the DT cord-354133-11b0d499 83 18 crude crude JJ cord-354133-11b0d499 83 19 estimate estimate NN cord-354133-11b0d499 83 20 of of IN cord-354133-11b0d499 83 21 8.4 8.4 CD cord-354133-11b0d499 83 22 % % NN cord-354133-11b0d499 83 23 . . . cord-354133-11b0d499 84 1 It -PRON- PRP cord-354133-11b0d499 84 2 appears appear VBZ cord-354133-11b0d499 84 3 that that IN cord-354133-11b0d499 84 4 this this DT cord-354133-11b0d499 84 5 simple simple JJ cord-354133-11b0d499 84 6 analysis analysis NN cord-354133-11b0d499 84 7 generates generate VBZ cord-354133-11b0d499 84 8 two two CD cord-354133-11b0d499 84 9 parameters parameter NNS cord-354133-11b0d499 84 10 of of IN cord-354133-11b0d499 84 11 significant significant JJ cord-354133-11b0d499 84 12 interest interest NN cord-354133-11b0d499 84 13 : : : cord-354133-11b0d499 84 14 the the DT cord-354133-11b0d499 84 15 apparent apparent JJ cord-354133-11b0d499 84 16 delay delay NN cord-354133-11b0d499 84 17 between between IN cord-354133-11b0d499 84 18 reporting reporting NN cord-354133-11b0d499 84 19 of of IN cord-354133-11b0d499 84 20 related related JJ cord-354133-11b0d499 84 21 cases case NNS cord-354133-11b0d499 84 22 and and CC cord-354133-11b0d499 84 23 deaths death NNS cord-354133-11b0d499 84 24 , , , cord-354133-11b0d499 84 25 and and CC cord-354133-11b0d499 84 26 the the DT cord-354133-11b0d499 84 27 CFR CFR NNP cord-354133-11b0d499 84 28 . . . cord-354133-11b0d499 85 1 The the DT cord-354133-11b0d499 85 2 estimates estimate NNS cord-354133-11b0d499 85 3 of of IN cord-354133-11b0d499 85 4 these these DT cord-354133-11b0d499 85 5 parameters parameter NNS cord-354133-11b0d499 85 6 ( ( -LRB- cord-354133-11b0d499 85 7 which which WDT cord-354133-11b0d499 85 8 can can MD cord-354133-11b0d499 85 9 be be VB cord-354133-11b0d499 85 10 determined determine VBN cord-354133-11b0d499 85 11 unequivocally unequivocally RB cord-354133-11b0d499 85 12 once once IN cord-354133-11b0d499 85 13 an an DT cord-354133-11b0d499 85 14 outbreak outbreak NN cord-354133-11b0d499 85 15 is be VBZ cord-354133-11b0d499 85 16 concluded conclude VBN cord-354133-11b0d499 85 17 ) ) -RRB- cord-354133-11b0d499 85 18 can can MD cord-354133-11b0d499 85 19 be be VB cord-354133-11b0d499 85 20 calculated calculate VBN cord-354133-11b0d499 85 21 during during IN cord-354133-11b0d499 85 22 the the DT cord-354133-11b0d499 85 23 course course NN cord-354133-11b0d499 85 24 of of IN cord-354133-11b0d499 85 25 an an DT cord-354133-11b0d499 85 26 outbreak outbreak NN cord-354133-11b0d499 85 27 and and CC cord-354133-11b0d499 85 28 give give VB cord-354133-11b0d499 85 29 a a DT cord-354133-11b0d499 85 30 better well JJR cord-354133-11b0d499 85 31 approximation approximation NN cord-354133-11b0d499 85 32 than than IN cord-354133-11b0d499 85 33 the the DT cord-354133-11b0d499 85 34 crude crude JJ cord-354133-11b0d499 85 35 CFR CFR NNP cord-354133-11b0d499 85 36 . . . cord-354133-11b0d499 86 1 It -PRON- PRP cord-354133-11b0d499 86 2 should should MD cord-354133-11b0d499 86 3 be be VB cord-354133-11b0d499 86 4 noted note VBN cord-354133-11b0d499 86 5 that that IN cord-354133-11b0d499 86 6 such such PDT cord-354133-11b0d499 86 7 an an DT cord-354133-11b0d499 86 8 analysis analysis NN cord-354133-11b0d499 86 9 can can MD cord-354133-11b0d499 86 10 not not RB cord-354133-11b0d499 86 11 be be VB cord-354133-11b0d499 86 12 applied apply VBN cord-354133-11b0d499 86 13 during during IN cord-354133-11b0d499 86 14 purely purely RB cord-354133-11b0d499 86 15 exponential exponential JJ cord-354133-11b0d499 86 16 growth growth NN cord-354133-11b0d499 86 17 , , , cord-354133-11b0d499 86 18 because because IN cord-354133-11b0d499 86 19 time time NN cord-354133-11b0d499 86 20 - - HYPH cord-354133-11b0d499 86 21 shifting shifting NN cord-354133-11b0d499 86 22 ( ( -LRB- cord-354133-11b0d499 86 23 horizontally horizontally RB cord-354133-11b0d499 86 24 ) ) -RRB- cord-354133-11b0d499 86 25 and and CC cord-354133-11b0d499 86 26 scaling scale VBG cord-354133-11b0d499 86 27 ( ( -LRB- cord-354133-11b0d499 86 28 vertically vertically RB cord-354133-11b0d499 86 29 ) ) -RRB- cord-354133-11b0d499 86 30 an an DT cord-354133-11b0d499 86 31 exponential exponential JJ cord-354133-11b0d499 86 32 function function NN cord-354133-11b0d499 86 33 are be VBP cord-354133-11b0d499 86 34 equivalent equivalent JJ cord-354133-11b0d499 86 35 operations operation NNS cord-354133-11b0d499 86 36 , , , cord-354133-11b0d499 86 37 as as IN cord-354133-11b0d499 86 38 : : : cord-354133-11b0d499 86 39 " " `` cord-354133-11b0d499 86 40 ( ( -LRB- cord-354133-11b0d499 86 41 $ $ $ cord-354133-11b0d499 86 42 % % NN cord-354133-11b0d499 86 43 $ $ $ cord-354133-11b0d499 86 44 ! ! . cord-354133-11b0d499 86 45 ) ) -RRB- cord-354133-11b0d499 87 1 = = NFP cord-354133-11b0d499 87 2 [ [ -LRB- cord-354133-11b0d499 87 3 % % NN cord-354133-11b0d499 87 4 " " `` cord-354133-11b0d499 87 5 $ $ $ cord-354133-11b0d499 87 6 ! ! . cord-354133-11b0d499 87 7 ] ] -RRB- cord-354133-11b0d499 88 1 " " `` cord-354133-11b0d499 88 2 $ $ $ cord-354133-11b0d499 88 3 = = SYM cord-354133-11b0d499 88 4 " " '' cord-354133-11b0d499 88 5 $ $ $ cord-354133-11b0d499 88 6 , , , cord-354133-11b0d499 88 7 which which WDT cord-354133-11b0d499 88 8 means mean VBZ cord-354133-11b0d499 88 9 that that IN cord-354133-11b0d499 88 10 any any DT cord-354133-11b0d499 88 11 value value NN cord-354133-11b0d499 88 12 of of IN cord-354133-11b0d499 88 13 ! ! . cord-354133-11b0d499 88 14 will will MD cord-354133-11b0d499 88 15 give give VB cord-354133-11b0d499 88 16 an an DT cord-354133-11b0d499 88 17 equivalent equivalent JJ cord-354133-11b0d499 88 18 relationship relationship NN cord-354133-11b0d499 88 19 between between IN cord-354133-11b0d499 88 20 ( ( -LRB- cord-354133-11b0d499 88 21 − − NNP cord-354133-11b0d499 88 22 ! ! . cord-354133-11b0d499 88 23 ) ) -RRB- cord-354133-11b0d499 89 1 and and CC cord-354133-11b0d499 89 2 ( ( -LRB- cord-354133-11b0d499 89 3 ) ) -RRB- cord-354133-11b0d499 89 4 with with IN cord-354133-11b0d499 89 5 gradient gradient NN cord-354133-11b0d499 89 6 depending depend VBG cord-354133-11b0d499 89 7 on on IN cord-354133-11b0d499 89 8 ! ! . cord-354133-11b0d499 89 9 . . . cord-354133-11b0d499 90 1 Therefore therefore RB cord-354133-11b0d499 90 2 , , , cord-354133-11b0d499 90 3 the the DT cord-354133-11b0d499 90 4 TSD TSD NNP cord-354133-11b0d499 90 5 analysis analysis NN cord-354133-11b0d499 90 6 is be VBZ cord-354133-11b0d499 90 7 only only RB cord-354133-11b0d499 90 8 valid valid JJ cord-354133-11b0d499 90 9 once once IN cord-354133-11b0d499 90 10 exponential exponential JJ cord-354133-11b0d499 90 11 growth growth NN cord-354133-11b0d499 90 12 ends end VBZ cord-354133-11b0d499 90 13 and and CC cord-354133-11b0d499 90 14 the the DT cord-354133-11b0d499 90 15 daily daily JJ cord-354133-11b0d499 90 16 case case NN cord-354133-11b0d499 90 17 rate rate NN cord-354133-11b0d499 90 18 is be VBZ cord-354133-11b0d499 90 19 approaching approach VBG cord-354133-11b0d499 90 20 ( ( -LRB- cord-354133-11b0d499 90 21 or or CC cord-354133-11b0d499 90 22 past past NN cord-354133-11b0d499 90 23 ) ) -RRB- cord-354133-11b0d499 91 1 its -PRON- PRP$ cord-354133-11b0d499 91 2 peak peak NN cord-354133-11b0d499 91 3 . . . cord-354133-11b0d499 92 1 Alternatively alternatively RB cord-354133-11b0d499 92 2 , , , cord-354133-11b0d499 92 3 an an DT cord-354133-11b0d499 92 4 estimate estimate NN cord-354133-11b0d499 92 5 for for IN cord-354133-11b0d499 92 6 ! ! . cord-354133-11b0d499 92 7 could could MD cord-354133-11b0d499 92 8 be be VB cord-354133-11b0d499 92 9 used use VBN cord-354133-11b0d499 92 10 , , , cord-354133-11b0d499 92 11 but but CC cord-354133-11b0d499 92 12 this this DT cord-354133-11b0d499 92 13 reduces reduce VBZ cord-354133-11b0d499 92 14 the the DT cord-354133-11b0d499 92 15 simplicity simplicity NN cord-354133-11b0d499 92 16 and and CC cord-354133-11b0d499 92 17 transparency transparency NN cord-354133-11b0d499 92 18 of of IN cord-354133-11b0d499 92 19 the the DT cord-354133-11b0d499 92 20 model model NN cord-354133-11b0d499 92 21 . . . cord-354133-11b0d499 93 1 We -PRON- PRP cord-354133-11b0d499 93 2 note note VBP cord-354133-11b0d499 93 3 that that IN cord-354133-11b0d499 93 4 others other NNS cord-354133-11b0d499 93 5 have have VBP cord-354133-11b0d499 93 6 calculated calculate VBN cord-354133-11b0d499 93 7 an an DT cord-354133-11b0d499 93 8 " " `` cord-354133-11b0d499 93 9 adjusted adjust VBN cord-354133-11b0d499 93 10 " " '' cord-354133-11b0d499 93 11 CFR CFR NNP cord-354133-11b0d499 93 12 early early RB cord-354133-11b0d499 93 13 in in IN cord-354133-11b0d499 93 14 the the DT cord-354133-11b0d499 93 15 COVID-19 covid-19 JJ cord-354133-11b0d499 93 16 outbreak outbreak NN cord-354133-11b0d499 93 17 using use VBG cord-354133-11b0d499 93 18 an an DT cord-354133-11b0d499 93 19 equivalent equivalent JJ cord-354133-11b0d499 93 20 method method NN cord-354133-11b0d499 93 21 with with IN cord-354133-11b0d499 93 22 an an DT cord-354133-11b0d499 93 23 assumed assume VBN cord-354133-11b0d499 93 24 . . . cord-354133-11b0d499 94 1 CC CC NNP cord-354133-11b0d499 94 2 - - HYPH cord-354133-11b0d499 94 3 BY BY NNP cord-354133-11b0d499 94 4 - - HYPH cord-354133-11b0d499 94 5 NC NC NNP cord-354133-11b0d499 94 6 - - HYPH cord-354133-11b0d499 94 7 ND ND NNP cord-354133-11b0d499 94 8 4.0 4.0 CD cord-354133-11b0d499 94 9 International international JJ cord-354133-11b0d499 94 10 license license NN cord-354133-11b0d499 94 11 It -PRON- PRP cord-354133-11b0d499 94 12 is be VBZ cord-354133-11b0d499 94 13 made make VBN cord-354133-11b0d499 94 14 available available JJ cord-354133-11b0d499 94 15 under under IN cord-354133-11b0d499 94 16 a a DT cord-354133-11b0d499 94 17 perpetuity perpetuity NN cord-354133-11b0d499 94 18 . . . cord-354133-11b0d499 95 1 is be VBZ cord-354133-11b0d499 95 2 the the DT cord-354133-11b0d499 95 3 author author NN cord-354133-11b0d499 95 4 / / SYM cord-354133-11b0d499 95 5 funder funder NN cord-354133-11b0d499 95 6 , , , cord-354133-11b0d499 95 7 who who WP cord-354133-11b0d499 95 8 has have VBZ cord-354133-11b0d499 95 9 granted grant VBN cord-354133-11b0d499 95 10 medRxiv medRxiv NNS cord-354133-11b0d499 95 11 a a DT cord-354133-11b0d499 95 12 license license NN cord-354133-11b0d499 95 13 to to TO cord-354133-11b0d499 95 14 display display VB cord-354133-11b0d499 95 15 the the DT cord-354133-11b0d499 95 16 preprint preprint NN cord-354133-11b0d499 95 17 in in IN cord-354133-11b0d499 95 18 ( ( -LRB- cord-354133-11b0d499 95 19 which which WDT cord-354133-11b0d499 95 20 was be VBD cord-354133-11b0d499 95 21 not not RB cord-354133-11b0d499 95 22 certified certify VBN cord-354133-11b0d499 95 23 by by IN cord-354133-11b0d499 95 24 peer peer NN cord-354133-11b0d499 95 25 review review NN cord-354133-11b0d499 95 26 ) ) -RRB- cord-354133-11b0d499 95 27 preprint preprint NN cord-354133-11b0d499 96 1 The the DT cord-354133-11b0d499 96 2 copyright copyright NN cord-354133-11b0d499 96 3 holder holder NN cord-354133-11b0d499 96 4 for for IN cord-354133-11b0d499 96 5 this this DT cord-354133-11b0d499 96 6 this this DT cord-354133-11b0d499 96 7 version version NN cord-354133-11b0d499 96 8 posted post VBD cord-354133-11b0d499 96 9 October October NNP cord-354133-11b0d499 96 10 27 27 CD cord-354133-11b0d499 96 11 , , , cord-354133-11b0d499 96 12 2020 2020 CD cord-354133-11b0d499 96 13 . . . cord-354133-11b0d499 97 1 ; ; : cord-354133-11b0d499 97 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 97 3 doi doi NN cord-354133-11b0d499 97 4 : : : cord-354133-11b0d499 98 1 medRxiv medRxiv NNS cord-354133-11b0d499 98 2 preprint preprint NN cord-354133-11b0d499 98 3 value value NN cord-354133-11b0d499 98 4 of of IN cord-354133-11b0d499 98 5 the the DT cord-354133-11b0d499 98 6 time time NN cord-354133-11b0d499 98 7 delay delay NN cord-354133-11b0d499 98 8 between between IN cord-354133-11b0d499 98 9 onset onset NN cord-354133-11b0d499 98 10 and and CC cord-354133-11b0d499 98 11 death death NN cord-354133-11b0d499 98 12 ( ( -LRB- cord-354133-11b0d499 98 13 because because IN cord-354133-11b0d499 98 14 the the DT cord-354133-11b0d499 98 15 true true JJ cord-354133-11b0d499 98 16 value value NN cord-354133-11b0d499 98 17 was be VBD cord-354133-11b0d499 98 18 not not RB cord-354133-11b0d499 98 19 known know VBN cord-354133-11b0d499 98 20 ) ) -RRB- cord-354133-11b0d499 98 21 : : : cord-354133-11b0d499 99 1 Yuan yuan NN cord-354133-11b0d499 99 2 and and CC cord-354133-11b0d499 99 3 colleagues colleague NNS cord-354133-11b0d499 99 4 [ [ -LRB- cord-354133-11b0d499 99 5 18 18 CD cord-354133-11b0d499 99 6 ] ] -RRB- cord-354133-11b0d499 99 7 chose choose VBD cord-354133-11b0d499 99 8 sample sample NN cord-354133-11b0d499 99 9 values value NNS cord-354133-11b0d499 99 10 of of IN cord-354133-11b0d499 99 11 one one CD cord-354133-11b0d499 99 12 , , , cord-354133-11b0d499 99 13 three three CD cord-354133-11b0d499 99 14 and and CC cord-354133-11b0d499 99 15 five five CD cord-354133-11b0d499 99 16 days day NNS cord-354133-11b0d499 99 17 to to TO cord-354133-11b0d499 99 18 give give VB cord-354133-11b0d499 99 19 estimates estimate NNS cord-354133-11b0d499 99 20 from from IN cord-354133-11b0d499 99 21 3 3 CD cord-354133-11b0d499 99 22 - - SYM cord-354133-11b0d499 99 23 13 13 CD cord-354133-11b0d499 99 24 % % NN cord-354133-11b0d499 99 25 for for IN cord-354133-11b0d499 99 26 Italy Italy NNP cord-354133-11b0d499 99 27 in in IN cord-354133-11b0d499 99 28 early early JJ cord-354133-11b0d499 99 29 March March NNP cord-354133-11b0d499 99 30 , , , cord-354133-11b0d499 99 31 while while IN cord-354133-11b0d499 99 32 Wilson Wilson NNP cord-354133-11b0d499 99 33 and and CC cord-354133-11b0d499 99 34 colleagues colleague NNS cord-354133-11b0d499 99 35 [ [ -LRB- cord-354133-11b0d499 99 36 19 19 CD cord-354133-11b0d499 99 37 ] ] -RRB- cord-354133-11b0d499 99 38 used use VBN cord-354133-11b0d499 99 39 13 13 CD cord-354133-11b0d499 99 40 days day NNS cord-354133-11b0d499 99 41 to to TO cord-354133-11b0d499 99 42 give give VB cord-354133-11b0d499 99 43 0.8 0.8 CD cord-354133-11b0d499 99 44 - - SYM cord-354133-11b0d499 99 45 3.5 3.5 CD cord-354133-11b0d499 99 46 % % NN cord-354133-11b0d499 99 47 for for IN cord-354133-11b0d499 99 48 China China NNP cord-354133-11b0d499 99 49 in in IN cord-354133-11b0d499 99 50 early early JJ cord-354133-11b0d499 99 51 March March NNP cord-354133-11b0d499 99 52 . . . cord-354133-11b0d499 100 1 To to TO cord-354133-11b0d499 100 2 test test VB cord-354133-11b0d499 100 3 the the DT cord-354133-11b0d499 100 4 TSD TSD NNP cord-354133-11b0d499 100 5 analysis analysis NN cord-354133-11b0d499 100 6 method method NN cord-354133-11b0d499 100 7 in in IN cord-354133-11b0d499 100 8 determining determine VBG cord-354133-11b0d499 100 9 CFR CFR NNP cord-354133-11b0d499 100 10 in in IN cord-354133-11b0d499 100 11 the the DT cord-354133-11b0d499 100 12 middle middle NN cord-354133-11b0d499 100 13 of of IN cord-354133-11b0d499 100 14 an an DT cord-354133-11b0d499 100 15 outbreak outbreak NN cord-354133-11b0d499 100 16 , , , cord-354133-11b0d499 100 17 and and CC cord-354133-11b0d499 100 18 compare compare VB cord-354133-11b0d499 100 19 to to IN cord-354133-11b0d499 100 20 alternative alternative JJ cord-354133-11b0d499 100 21 methods method NNS cord-354133-11b0d499 100 22 , , , cord-354133-11b0d499 100 23 we -PRON- PRP cord-354133-11b0d499 100 24 analyse analyse VBP cord-354133-11b0d499 100 25 data datum NNS cord-354133-11b0d499 100 26 from from IN cord-354133-11b0d499 100 27 the the DT cord-354133-11b0d499 100 28 SARS SARS NNP cord-354133-11b0d499 100 29 2003 2003 CD cord-354133-11b0d499 100 30 outbreak outbreak NN cord-354133-11b0d499 100 31 in in IN cord-354133-11b0d499 100 32 Hong Hong NNP cord-354133-11b0d499 100 33 Kong Kong NNP cord-354133-11b0d499 100 34 is be VBZ cord-354133-11b0d499 100 35 the the DT cord-354133-11b0d499 100 36 author author NN cord-354133-11b0d499 100 37 / / SYM cord-354133-11b0d499 100 38 funder funder NN cord-354133-11b0d499 100 39 , , , cord-354133-11b0d499 100 40 who who WP cord-354133-11b0d499 100 41 has have VBZ cord-354133-11b0d499 100 42 granted grant VBN cord-354133-11b0d499 100 43 medRxiv medRxiv NNS cord-354133-11b0d499 100 44 a a DT cord-354133-11b0d499 100 45 license license NN cord-354133-11b0d499 100 46 to to TO cord-354133-11b0d499 100 47 display display VB cord-354133-11b0d499 100 48 the the DT cord-354133-11b0d499 100 49 preprint preprint NN cord-354133-11b0d499 100 50 in in IN cord-354133-11b0d499 100 51 ( ( -LRB- cord-354133-11b0d499 100 52 which which WDT cord-354133-11b0d499 100 53 was be VBD cord-354133-11b0d499 100 54 not not RB cord-354133-11b0d499 100 55 certified certify VBN cord-354133-11b0d499 100 56 by by IN cord-354133-11b0d499 100 57 peer peer NN cord-354133-11b0d499 100 58 review review NN cord-354133-11b0d499 100 59 ) ) -RRB- cord-354133-11b0d499 100 60 preprint preprint NN cord-354133-11b0d499 101 1 The the DT cord-354133-11b0d499 101 2 copyright copyright NN cord-354133-11b0d499 101 3 holder holder NN cord-354133-11b0d499 101 4 for for IN cord-354133-11b0d499 101 5 this this DT cord-354133-11b0d499 101 6 this this DT cord-354133-11b0d499 101 7 version version NN cord-354133-11b0d499 101 8 posted post VBD cord-354133-11b0d499 101 9 October October NNP cord-354133-11b0d499 101 10 27 27 CD cord-354133-11b0d499 101 11 , , , cord-354133-11b0d499 101 12 2020 2020 CD cord-354133-11b0d499 101 13 . . . cord-354133-11b0d499 102 1 ; ; : cord-354133-11b0d499 102 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 102 3 doi doi NN cord-354133-11b0d499 102 4 : : : cord-354133-11b0d499 102 5 medRxiv medRxiv NNP cord-354133-11b0d499 102 6 preprint preprint NN cord-354133-11b0d499 102 7 Figure Figure NNP cord-354133-11b0d499 102 8 6 6 CD cord-354133-11b0d499 102 9 . . . cord-354133-11b0d499 103 1 To to TO cord-354133-11b0d499 103 2 compare compare VB cord-354133-11b0d499 103 3 , , , cord-354133-11b0d499 103 4 on on IN cord-354133-11b0d499 103 5 17 17 CD cord-354133-11b0d499 103 6 April April NNP cord-354133-11b0d499 103 7 the the DT cord-354133-11b0d499 103 8 crude crude JJ cord-354133-11b0d499 103 9 CFR CFR NNP cord-354133-11b0d499 103 10 is be VBZ cord-354133-11b0d499 103 11 5.3 5.3 CD cord-354133-11b0d499 103 12 % % NN cord-354133-11b0d499 103 13 , , , cord-354133-11b0d499 103 14 which which WDT cord-354133-11b0d499 103 15 is be VBZ cord-354133-11b0d499 103 16 a a DT cord-354133-11b0d499 103 17 significant significant JJ cord-354133-11b0d499 103 18 underestimate underestimate NN cord-354133-11b0d499 103 19 of of IN cord-354133-11b0d499 103 20 the the DT cord-354133-11b0d499 103 21 true true JJ cord-354133-11b0d499 103 22 value value NN cord-354133-11b0d499 103 23 . . . cord-354133-11b0d499 104 1 The the DT cord-354133-11b0d499 104 2 delay delay NN cord-354133-11b0d499 104 3 time time NN cord-354133-11b0d499 104 4 of of IN cord-354133-11b0d499 104 5 22 22 CD cord-354133-11b0d499 104 6 days day NNS cord-354133-11b0d499 104 7 is be VBZ cord-354133-11b0d499 104 8 consistent consistent JJ cord-354133-11b0d499 104 9 with with IN cord-354133-11b0d499 104 10 observations observation NNS cord-354133-11b0d499 104 11 that that IN cord-354133-11b0d499 104 12 the the DT cord-354133-11b0d499 104 13 delay delay NN cord-354133-11b0d499 104 14 between between IN cord-354133-11b0d499 104 15 onset onset NN cord-354133-11b0d499 104 16 and and CC cord-354133-11b0d499 104 17 death death NN cord-354133-11b0d499 104 18 for for IN cord-354133-11b0d499 104 19 SARS SARS NNP cord-354133-11b0d499 104 20 is be VBZ cord-354133-11b0d499 104 21 approximately approximately RB cord-354133-11b0d499 104 22 three three CD cord-354133-11b0d499 104 23 weeks week NNS cord-354133-11b0d499 104 24 [ [ -LRB- cord-354133-11b0d499 104 25 21 21 CD cord-354133-11b0d499 104 26 ] ] -RRB- cord-354133-11b0d499 104 27 . . . cord-354133-11b0d499 105 1 We -PRON- PRP cord-354133-11b0d499 105 2 also also RB cord-354133-11b0d499 105 3 applied apply VBD cord-354133-11b0d499 105 4 TSD TSD NNP cord-354133-11b0d499 105 5 analysis analysis NN cord-354133-11b0d499 105 6 to to IN cord-354133-11b0d499 105 7 SARS SARS NNP cord-354133-11b0d499 105 8 data datum NNS cord-354133-11b0d499 105 9 for for IN cord-354133-11b0d499 105 10 other other JJ cord-354133-11b0d499 105 11 countries country NNS cord-354133-11b0d499 105 12 , , , cord-354133-11b0d499 105 13 giving give VBG cord-354133-11b0d499 105 14 a a DT cord-354133-11b0d499 105 15 calculated calculate VBN cord-354133-11b0d499 105 16 CFR CFR NNP cord-354133-11b0d499 105 17 of of IN cord-354133-11b0d499 105 18 15 15 CD cord-354133-11b0d499 105 19 % % NN cord-354133-11b0d499 105 20 for for IN cord-354133-11b0d499 105 21 Singapore Singapore NNP cord-354133-11b0d499 105 22 and and CC cord-354133-11b0d499 105 23 Canada Canada NNP cord-354133-11b0d499 105 24 ( ( -LRB- cord-354133-11b0d499 105 25 although although IN cord-354133-11b0d499 105 26 data datum NNS cord-354133-11b0d499 105 27 are be VBP cord-354133-11b0d499 105 28 noisy noisy JJ cord-354133-11b0d499 105 29 ) ) -RRB- cord-354133-11b0d499 105 30 , , , cord-354133-11b0d499 105 31 and and CC cord-354133-11b0d499 105 32 13 13 CD cord-354133-11b0d499 105 33 % % NN cord-354133-11b0d499 105 34 for for IN cord-354133-11b0d499 105 35 Taiwan Taiwan NNP cord-354133-11b0d499 105 36 . . . cord-354133-11b0d499 106 1 We -PRON- PRP cord-354133-11b0d499 106 2 can can MD cord-354133-11b0d499 106 3 compare compare VB cord-354133-11b0d499 106 4 these these DT cord-354133-11b0d499 106 5 estimates estimate NNS cord-354133-11b0d499 106 6 of of IN cord-354133-11b0d499 106 7 the the DT cord-354133-11b0d499 106 8 CFR CFR NNP cord-354133-11b0d499 106 9 with with IN cord-354133-11b0d499 106 10 the the DT cord-354133-11b0d499 106 11 more more RBR cord-354133-11b0d499 106 12 complex complex JJ cord-354133-11b0d499 106 13 mathematical mathematical JJ cord-354133-11b0d499 106 14 models model NNS cord-354133-11b0d499 106 15 of of IN cord-354133-11b0d499 106 16 Nishiura Nishiura NNP cord-354133-11b0d499 106 17 and and CC cord-354133-11b0d499 106 18 coworkers coworker NNS cord-354133-11b0d499 106 19 [ [ -LRB- cord-354133-11b0d499 106 20 22 22 CD cord-354133-11b0d499 106 21 ] ] -RRB- cord-354133-11b0d499 106 22 and and CC cord-354133-11b0d499 106 23 Ghani Ghani NNP cord-354133-11b0d499 106 24 and and CC cord-354133-11b0d499 106 25 coworkers coworker NNS cord-354133-11b0d499 106 26 [ [ -LRB- cord-354133-11b0d499 106 27 15 15 CD cord-354133-11b0d499 106 28 ] ] -RRB- cord-354133-11b0d499 106 29 for for IN cord-354133-11b0d499 106 30 the the DT cord-354133-11b0d499 106 31 same same JJ cord-354133-11b0d499 106 32 SARS SARS NNP cord-354133-11b0d499 106 33 outbreak outbreak NN cord-354133-11b0d499 106 34 . . . cord-354133-11b0d499 107 1 The the DT cord-354133-11b0d499 107 2 simple simple JJ cord-354133-11b0d499 107 3 TSD TSD NNP cord-354133-11b0d499 107 4 analysis analysis NN cord-354133-11b0d499 107 5 gives give VBZ cord-354133-11b0d499 107 6 better well JJR cord-354133-11b0d499 107 7 predictions prediction NNS cord-354133-11b0d499 107 8 than than IN cord-354133-11b0d499 107 9 both both CC cord-354133-11b0d499 107 10 the the DT cord-354133-11b0d499 107 11 parametric parametric JJ cord-354133-11b0d499 107 12 mixture mixture NN cord-354133-11b0d499 107 13 model model NN cord-354133-11b0d499 107 14 and and CC cord-354133-11b0d499 107 15 modified modify VBD cord-354133-11b0d499 107 16 Kaplan Kaplan NNP cord-354133-11b0d499 107 17 - - HYPH cord-354133-11b0d499 107 18 Meier Meier NNP cord-354133-11b0d499 107 19 method method NN cord-354133-11b0d499 107 20 described describe VBN cord-354133-11b0d499 107 21 by by IN cord-354133-11b0d499 107 22 Ghani Ghani NNP cord-354133-11b0d499 107 23 et et NNP cord-354133-11b0d499 107 24 al al NNP cord-354133-11b0d499 107 25 . . . cord-354133-11b0d499 108 1 [ [ -LRB- cord-354133-11b0d499 108 2 15 15 CD cord-354133-11b0d499 108 3 ] ] -RRB- cord-354133-11b0d499 108 4 , , , cord-354133-11b0d499 108 5 which which WDT cord-354133-11b0d499 108 6 use use VBP cord-354133-11b0d499 108 7 individual individual JJ cord-354133-11b0d499 108 8 case case NN cord-354133-11b0d499 108 9 data datum NNS cord-354133-11b0d499 108 10 . . . cord-354133-11b0d499 109 1 CC CC NNP cord-354133-11b0d499 109 2 - - HYPH cord-354133-11b0d499 109 3 BY BY NNP cord-354133-11b0d499 109 4 - - HYPH cord-354133-11b0d499 109 5 NC NC NNP cord-354133-11b0d499 109 6 - - HYPH cord-354133-11b0d499 109 7 ND ND NNP cord-354133-11b0d499 109 8 4.0 4.0 CD cord-354133-11b0d499 109 9 International international JJ cord-354133-11b0d499 109 10 license license NN cord-354133-11b0d499 109 11 It -PRON- PRP cord-354133-11b0d499 109 12 is be VBZ cord-354133-11b0d499 109 13 made make VBN cord-354133-11b0d499 109 14 available available JJ cord-354133-11b0d499 109 15 under under IN cord-354133-11b0d499 109 16 a a DT cord-354133-11b0d499 109 17 perpetuity perpetuity NN cord-354133-11b0d499 109 18 . . . cord-354133-11b0d499 110 1 is be VBZ cord-354133-11b0d499 110 2 the the DT cord-354133-11b0d499 110 3 author author NN cord-354133-11b0d499 110 4 / / SYM cord-354133-11b0d499 110 5 funder funder NN cord-354133-11b0d499 110 6 , , , cord-354133-11b0d499 110 7 who who WP cord-354133-11b0d499 110 8 has have VBZ cord-354133-11b0d499 110 9 granted grant VBN cord-354133-11b0d499 110 10 medRxiv medRxiv NNS cord-354133-11b0d499 110 11 a a DT cord-354133-11b0d499 110 12 license license NN cord-354133-11b0d499 110 13 to to TO cord-354133-11b0d499 110 14 display display VB cord-354133-11b0d499 110 15 the the DT cord-354133-11b0d499 110 16 preprint preprint NN cord-354133-11b0d499 110 17 in in IN cord-354133-11b0d499 110 18 ( ( -LRB- cord-354133-11b0d499 110 19 which which WDT cord-354133-11b0d499 110 20 was be VBD cord-354133-11b0d499 110 21 not not RB cord-354133-11b0d499 110 22 certified certify VBN cord-354133-11b0d499 110 23 by by IN cord-354133-11b0d499 110 24 peer peer NN cord-354133-11b0d499 110 25 review review NN cord-354133-11b0d499 110 26 ) ) -RRB- cord-354133-11b0d499 110 27 preprint preprint NN cord-354133-11b0d499 111 1 The the DT cord-354133-11b0d499 111 2 copyright copyright NN cord-354133-11b0d499 111 3 holder holder NN cord-354133-11b0d499 111 4 for for IN cord-354133-11b0d499 111 5 this this DT cord-354133-11b0d499 111 6 this this DT cord-354133-11b0d499 111 7 version version NN cord-354133-11b0d499 111 8 posted post VBD cord-354133-11b0d499 111 9 October October NNP cord-354133-11b0d499 111 10 27 27 CD cord-354133-11b0d499 111 11 , , , cord-354133-11b0d499 111 12 2020 2020 CD cord-354133-11b0d499 111 13 . . . cord-354133-11b0d499 112 1 ; ; : cord-354133-11b0d499 112 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 112 3 doi doi NN cord-354133-11b0d499 112 4 : : : cord-354133-11b0d499 113 1 medRxiv medRxiv NNP cord-354133-11b0d499 113 2 preprint preprint NN cord-354133-11b0d499 113 3 ( ( -LRB- cord-354133-11b0d499 113 4 dates date NNS cord-354133-11b0d499 113 5 of of IN cord-354133-11b0d499 113 6 hospitalisation hospitalisation NN cord-354133-11b0d499 113 7 and and CC cord-354133-11b0d499 113 8 death death NN cord-354133-11b0d499 113 9 or or CC cord-354133-11b0d499 113 10 discharge discharge NN cord-354133-11b0d499 113 11 from from IN cord-354133-11b0d499 113 12 hospital hospital NN cord-354133-11b0d499 113 13 ) ) -RRB- cord-354133-11b0d499 113 14 to to TO cord-354133-11b0d499 113 15 estimate estimate VB cord-354133-11b0d499 113 16 CFR CFR NNP cord-354133-11b0d499 113 17 using use VBG cord-354133-11b0d499 113 18 statistical statistical JJ cord-354133-11b0d499 113 19 methods method NNS cord-354133-11b0d499 113 20 . . . cord-354133-11b0d499 114 1 Such such JJ cord-354133-11b0d499 114 2 methods method NNS cord-354133-11b0d499 114 3 can can MD cord-354133-11b0d499 114 4 provide provide VB cord-354133-11b0d499 114 5 earlier early JJR cord-354133-11b0d499 114 6 estimates estimate NNS cord-354133-11b0d499 114 7 ( ( -LRB- cord-354133-11b0d499 114 8 from from IN cord-354133-11b0d499 114 9 1 1 CD cord-354133-11b0d499 114 10 April April NNP cord-354133-11b0d499 114 11 , , , cord-354133-11b0d499 114 12 giving give VBG cord-354133-11b0d499 114 13 around around RB cord-354133-11b0d499 114 14 7 7 CD cord-354133-11b0d499 114 15 - - SYM cord-354133-11b0d499 114 16 8 8 CD cord-354133-11b0d499 114 17 % % NN cord-354133-11b0d499 114 18 CFR CFR NNP cord-354133-11b0d499 114 19 ) ) -RRB- cord-354133-11b0d499 114 20 but but CC cord-354133-11b0d499 114 21 are be VBP cord-354133-11b0d499 114 22 less less RBR cord-354133-11b0d499 114 23 accurate accurate JJ cord-354133-11b0d499 114 24 at at IN cord-354133-11b0d499 114 25 this this DT cord-354133-11b0d499 114 26 early early JJ cord-354133-11b0d499 114 27 stage stage NN cord-354133-11b0d499 114 28 than than IN cord-354133-11b0d499 114 29 a a DT cord-354133-11b0d499 114 30 simple simple JJ cord-354133-11b0d499 114 31 estimate estimate NN cord-354133-11b0d499 114 32 of of IN cord-354133-11b0d499 114 33 CFR CFR NNP cord-354133-11b0d499 114 34 from from IN cord-354133-11b0d499 114 35 data datum NNS cord-354133-11b0d499 114 36 on on IN cord-354133-11b0d499 114 37 closed closed JJ cord-354133-11b0d499 114 38 cases case NNS cord-354133-11b0d499 114 39 ( ( -LRB- cord-354133-11b0d499 114 40 recoveries recovery NNS cord-354133-11b0d499 114 41 and and CC cord-354133-11b0d499 114 42 deaths death NNS cord-354133-11b0d499 114 43 ) ) -RRB- cord-354133-11b0d499 114 44 at at IN cord-354133-11b0d499 114 45 the the DT cord-354133-11b0d499 114 46 same same JJ cord-354133-11b0d499 114 47 dates date NNS cord-354133-11b0d499 114 48 [ [ -LRB- cord-354133-11b0d499 114 49 15 15 CD cord-354133-11b0d499 114 50 ] ] -RRB- cord-354133-11b0d499 114 51 , , , cord-354133-11b0d499 114 52 and and CC cord-354133-11b0d499 114 53 are be VBP cord-354133-11b0d499 114 54 later later RB cord-354133-11b0d499 114 55 outperformed outperform VBN cord-354133-11b0d499 114 56 by by IN cord-354133-11b0d499 114 57 our -PRON- PRP$ cord-354133-11b0d499 114 58 simple simple JJ cord-354133-11b0d499 114 59 TSD TSD NNP cord-354133-11b0d499 114 60 . . . cord-354133-11b0d499 115 1 CC CC NNP cord-354133-11b0d499 115 2 - - HYPH cord-354133-11b0d499 115 3 BY BY NNP cord-354133-11b0d499 115 4 - - HYPH cord-354133-11b0d499 115 5 NC NC NNP cord-354133-11b0d499 115 6 - - HYPH cord-354133-11b0d499 115 7 ND ND NNP cord-354133-11b0d499 115 8 4.0 4.0 CD cord-354133-11b0d499 115 9 International international JJ cord-354133-11b0d499 115 10 license license NN cord-354133-11b0d499 115 11 It -PRON- PRP cord-354133-11b0d499 115 12 is be VBZ cord-354133-11b0d499 115 13 made make VBN cord-354133-11b0d499 115 14 available available JJ cord-354133-11b0d499 115 15 under under IN cord-354133-11b0d499 115 16 a a DT cord-354133-11b0d499 115 17 perpetuity perpetuity NN cord-354133-11b0d499 115 18 . . . cord-354133-11b0d499 116 1 is be VBZ cord-354133-11b0d499 116 2 the the DT cord-354133-11b0d499 116 3 author author NN cord-354133-11b0d499 116 4 / / SYM cord-354133-11b0d499 116 5 funder funder NN cord-354133-11b0d499 116 6 , , , cord-354133-11b0d499 116 7 who who WP cord-354133-11b0d499 116 8 has have VBZ cord-354133-11b0d499 116 9 granted grant VBN cord-354133-11b0d499 116 10 medRxiv medRxiv NNS cord-354133-11b0d499 116 11 a a DT cord-354133-11b0d499 116 12 license license NN cord-354133-11b0d499 116 13 to to TO cord-354133-11b0d499 116 14 display display VB cord-354133-11b0d499 116 15 the the DT cord-354133-11b0d499 116 16 preprint preprint NN cord-354133-11b0d499 116 17 in in IN cord-354133-11b0d499 116 18 ( ( -LRB- cord-354133-11b0d499 116 19 which which WDT cord-354133-11b0d499 116 20 was be VBD cord-354133-11b0d499 116 21 not not RB cord-354133-11b0d499 116 22 certified certify VBN cord-354133-11b0d499 116 23 by by IN cord-354133-11b0d499 116 24 peer peer NN cord-354133-11b0d499 116 25 review review NN cord-354133-11b0d499 116 26 ) ) -RRB- cord-354133-11b0d499 116 27 preprint preprint NN cord-354133-11b0d499 117 1 The the DT cord-354133-11b0d499 117 2 copyright copyright NN cord-354133-11b0d499 117 3 holder holder NN cord-354133-11b0d499 117 4 for for IN cord-354133-11b0d499 117 5 this this DT cord-354133-11b0d499 117 6 this this DT cord-354133-11b0d499 117 7 version version NN cord-354133-11b0d499 117 8 posted post VBD cord-354133-11b0d499 117 9 October October NNP cord-354133-11b0d499 117 10 27 27 CD cord-354133-11b0d499 117 11 , , , cord-354133-11b0d499 117 12 2020 2020 CD cord-354133-11b0d499 117 13 . . . cord-354133-11b0d499 118 1 ; ; : cord-354133-11b0d499 118 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 118 3 doi doi NN cord-354133-11b0d499 118 4 : : : cord-354133-11b0d499 119 1 medRxiv medRxiv NNS cord-354133-11b0d499 119 2 preprint preprint NN cord-354133-11b0d499 119 3 Similarly similarly RB cord-354133-11b0d499 119 4 , , , cord-354133-11b0d499 119 5 the the DT cord-354133-11b0d499 119 6 model model NN cord-354133-11b0d499 119 7 of of IN cord-354133-11b0d499 119 8 Nishiura Nishiura NNP cord-354133-11b0d499 119 9 et et NNP cord-354133-11b0d499 119 10 al al NNP cord-354133-11b0d499 119 11 . . . cord-354133-11b0d499 120 1 [ [ -LRB- cord-354133-11b0d499 120 2 22 22 CD cord-354133-11b0d499 120 3 ] ] -RRB- cord-354133-11b0d499 120 4 can can MD cord-354133-11b0d499 120 5 provide provide VB cord-354133-11b0d499 120 6 much much RB cord-354133-11b0d499 120 7 earlier early JJR cord-354133-11b0d499 120 8 estimates estimate NNS cord-354133-11b0d499 120 9 of of IN cord-354133-11b0d499 120 10 CFR CFR NNP cord-354133-11b0d499 120 11 than than IN cord-354133-11b0d499 120 12 our -PRON- PRP$ cord-354133-11b0d499 120 13 analysis analysis NN cord-354133-11b0d499 120 14 but but CC cord-354133-11b0d499 120 15 the the DT cord-354133-11b0d499 120 16 accuracy accuracy NN cord-354133-11b0d499 120 17 of of IN cord-354133-11b0d499 120 18 these these DT cord-354133-11b0d499 120 19 estimates estimate NNS cord-354133-11b0d499 120 20 is be VBZ cord-354133-11b0d499 120 21 uncertain uncertain JJ cord-354133-11b0d499 120 22 and and CC cord-354133-11b0d499 120 23 depends depend VBZ cord-354133-11b0d499 120 24 on on IN cord-354133-11b0d499 120 25 the the DT cord-354133-11b0d499 120 26 assumptions assumption NNS cord-354133-11b0d499 120 27 made make VBN cord-354133-11b0d499 120 28 . . . cord-354133-11b0d499 121 1 Their -PRON- PRP$ cord-354133-11b0d499 121 2 analysis analysis NN cord-354133-11b0d499 121 3 requires require VBZ cord-354133-11b0d499 121 4 data datum NNS cord-354133-11b0d499 121 5 on on IN cord-354133-11b0d499 121 6 the the DT cord-354133-11b0d499 121 7 dates date NNS cord-354133-11b0d499 121 8 of of IN cord-354133-11b0d499 121 9 onset onset NN cord-354133-11b0d499 121 10 of of IN cord-354133-11b0d499 121 11 confirmed confirmed JJ cord-354133-11b0d499 121 12 cases case NNS cord-354133-11b0d499 121 13 and and CC cord-354133-11b0d499 121 14 the the DT cord-354133-11b0d499 121 15 distribution distribution NN cord-354133-11b0d499 121 16 of of IN cord-354133-11b0d499 121 17 times time NNS cord-354133-11b0d499 121 18 from from IN cord-354133-11b0d499 121 19 onset onset NN cord-354133-11b0d499 121 20 to to IN cord-354133-11b0d499 121 21 death death NN cord-354133-11b0d499 121 22 ; ; : cord-354133-11b0d499 121 23 the the DT cord-354133-11b0d499 121 24 latter latter JJ cord-354133-11b0d499 121 25 , , , cord-354133-11b0d499 121 26 in in IN cord-354133-11b0d499 121 27 particular particular JJ cord-354133-11b0d499 121 28 , , , cord-354133-11b0d499 121 29 is be VBZ cord-354133-11b0d499 121 30 poorly poorly RB cord-354133-11b0d499 121 31 known know VBN cord-354133-11b0d499 121 32 at at IN cord-354133-11b0d499 121 33 the the DT cord-354133-11b0d499 121 34 start start NN cord-354133-11b0d499 121 35 of of IN cord-354133-11b0d499 121 36 an an DT cord-354133-11b0d499 121 37 outbreak outbreak NN cord-354133-11b0d499 121 38 of of IN cord-354133-11b0d499 121 39 a a DT cord-354133-11b0d499 121 40 new new JJ cord-354133-11b0d499 121 41 disease disease NN cord-354133-11b0d499 121 42 . . . cord-354133-11b0d499 122 1 Nishiura Nishiura NNP cord-354133-11b0d499 122 2 et et NNP cord-354133-11b0d499 122 3 al al NNP cord-354133-11b0d499 122 4 . . . cord-354133-11b0d499 123 1 [ [ -LRB- cord-354133-11b0d499 123 2 22 22 CD cord-354133-11b0d499 123 3 ] ] -RRB- cord-354133-11b0d499 123 4 analyse analyse VB cord-354133-11b0d499 123 5 the the DT cord-354133-11b0d499 123 6 Hong Hong NNP cord-354133-11b0d499 123 7 Kong Kong NNP cord-354133-11b0d499 123 8 SARS SARS NNP cord-354133-11b0d499 123 9 data datum NNS cord-354133-11b0d499 123 10 by by IN cord-354133-11b0d499 123 11 assuming assume VBG cord-354133-11b0d499 123 12 a a DT cord-354133-11b0d499 123 13 simple simple JJ cord-354133-11b0d499 123 14 exponential exponential JJ cord-354133-11b0d499 123 15 distribution distribution NN cord-354133-11b0d499 123 16 for for IN cord-354133-11b0d499 123 17 the the DT cord-354133-11b0d499 123 18 time time NN cord-354133-11b0d499 123 19 between between IN cord-354133-11b0d499 123 20 onset onset NN cord-354133-11b0d499 123 21 and and CC cord-354133-11b0d499 123 22 death death NN cord-354133-11b0d499 123 23 , , , cord-354133-11b0d499 123 24 with with IN cord-354133-11b0d499 123 25 a a DT cord-354133-11b0d499 123 26 mean mean NN cord-354133-11b0d499 123 27 of of IN cord-354133-11b0d499 123 28 36 36 CD cord-354133-11b0d499 123 29 days day NNS cord-354133-11b0d499 123 30 ( ( -LRB- cord-354133-11b0d499 123 31 from from IN cord-354133-11b0d499 123 32 Donnelly Donnelly NNP cord-354133-11b0d499 123 33 [ [ -LRB- cord-354133-11b0d499 123 34 21 21 CD cord-354133-11b0d499 123 35 ] ] -RRB- cord-354133-11b0d499 123 36 for for IN cord-354133-11b0d499 123 37 SARS SARS NNP cord-354133-11b0d499 123 38 cases case NNS cord-354133-11b0d499 123 39 in in IN cord-354133-11b0d499 123 40 Hong Hong NNP cord-354133-11b0d499 123 41 Kong Kong NNP cord-354133-11b0d499 123 42 up up IN cord-354133-11b0d499 123 43 to to IN cord-354133-11b0d499 123 44 28 28 CD cord-354133-11b0d499 123 45 April April NNP cord-354133-11b0d499 123 46 , , , cord-354133-11b0d499 123 47 although although IN cord-354133-11b0d499 123 48 Donnelly Donnelly NNP cord-354133-11b0d499 123 49 used use VBD cord-354133-11b0d499 123 50 a a DT cord-354133-11b0d499 123 51 gamma gamma NN cord-354133-11b0d499 123 52 is be VBZ cord-354133-11b0d499 123 53 the the DT cord-354133-11b0d499 123 54 author author NN cord-354133-11b0d499 123 55 / / SYM cord-354133-11b0d499 123 56 funder funder NN cord-354133-11b0d499 123 57 , , , cord-354133-11b0d499 123 58 who who WP cord-354133-11b0d499 123 59 has have VBZ cord-354133-11b0d499 123 60 granted grant VBN cord-354133-11b0d499 123 61 medRxiv medRxiv NNS cord-354133-11b0d499 123 62 a a DT cord-354133-11b0d499 123 63 license license NN cord-354133-11b0d499 123 64 to to TO cord-354133-11b0d499 123 65 display display VB cord-354133-11b0d499 123 66 the the DT cord-354133-11b0d499 123 67 preprint preprint NN cord-354133-11b0d499 123 68 in in IN cord-354133-11b0d499 123 69 ( ( -LRB- cord-354133-11b0d499 123 70 which which WDT cord-354133-11b0d499 123 71 was be VBD cord-354133-11b0d499 123 72 not not RB cord-354133-11b0d499 123 73 certified certify VBN cord-354133-11b0d499 123 74 by by IN cord-354133-11b0d499 123 75 peer peer NN cord-354133-11b0d499 123 76 review review NN cord-354133-11b0d499 123 77 ) ) -RRB- cord-354133-11b0d499 123 78 preprint preprint NN cord-354133-11b0d499 124 1 The the DT cord-354133-11b0d499 124 2 copyright copyright NN cord-354133-11b0d499 124 3 holder holder NN cord-354133-11b0d499 124 4 for for IN cord-354133-11b0d499 124 5 this this DT cord-354133-11b0d499 124 6 this this DT cord-354133-11b0d499 124 7 version version NN cord-354133-11b0d499 124 8 posted post VBD cord-354133-11b0d499 124 9 October October NNP cord-354133-11b0d499 124 10 27 27 CD cord-354133-11b0d499 124 11 , , , cord-354133-11b0d499 124 12 2020 2020 CD cord-354133-11b0d499 124 13 . . . cord-354133-11b0d499 125 1 ; ; : cord-354133-11b0d499 125 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 125 3 doi doi NN cord-354133-11b0d499 125 4 : : : cord-354133-11b0d499 125 5 medRxiv medRxiv NNS cord-354133-11b0d499 125 6 preprint preprint NN cord-354133-11b0d499 125 7 distribution distribution NN cord-354133-11b0d499 125 8 ) ) -RRB- cord-354133-11b0d499 125 9 , , , cord-354133-11b0d499 125 10 and and CC cord-354133-11b0d499 125 11 using use VBG cord-354133-11b0d499 125 12 statistical statistical JJ cord-354133-11b0d499 125 13 sampling sampling NN cord-354133-11b0d499 125 14 to to TO cord-354133-11b0d499 125 15 predict predict VB cord-354133-11b0d499 125 16 the the DT cord-354133-11b0d499 125 17 CFR CFR NNP cord-354133-11b0d499 125 18 . . . cord-354133-11b0d499 126 1 The the DT cord-354133-11b0d499 126 2 fact fact NN cord-354133-11b0d499 126 3 that that IN cord-354133-11b0d499 126 4 this this DT cord-354133-11b0d499 126 5 model model NN cord-354133-11b0d499 126 6 provides provide VBZ cord-354133-11b0d499 126 7 a a DT cord-354133-11b0d499 126 8 reasonable reasonable JJ cord-354133-11b0d499 126 9 prediction prediction NN cord-354133-11b0d499 126 10 of of IN cord-354133-11b0d499 126 11 CFR CFR NNP cord-354133-11b0d499 126 12 at at IN cord-354133-11b0d499 126 13 a a DT cord-354133-11b0d499 126 14 specific specific JJ cord-354133-11b0d499 126 15 time time NN cord-354133-11b0d499 126 16 ( ( -LRB- cord-354133-11b0d499 126 17 around around IN cord-354133-11b0d499 126 18 the the DT cord-354133-11b0d499 126 19 end end NN cord-354133-11b0d499 126 20 of of IN cord-354133-11b0d499 126 21 March March NNP cord-354133-11b0d499 126 22 ) ) -RRB- cord-354133-11b0d499 126 23 is be VBZ cord-354133-11b0d499 126 24 likely likely RB cord-354133-11b0d499 126 25 fortuitous fortuitous JJ cord-354133-11b0d499 126 26 , , , cord-354133-11b0d499 126 27 given give VBN cord-354133-11b0d499 126 28 that that IN cord-354133-11b0d499 126 29 it -PRON- PRP cord-354133-11b0d499 126 30 involves involve VBZ cord-354133-11b0d499 126 31 scaling scale VBG cord-354133-11b0d499 126 32 the the DT cord-354133-11b0d499 126 33 crude crude JJ cord-354133-11b0d499 126 34 CFR CFR NNP cord-354133-11b0d499 126 35 by by IN cord-354133-11b0d499 126 36 a a DT cord-354133-11b0d499 126 37 constant constant JJ cord-354133-11b0d499 126 38 factor factor NN cord-354133-11b0d499 126 39 and and CC cord-354133-11b0d499 126 40 will will MD cord-354133-11b0d499 126 41 therefore therefore RB cord-354133-11b0d499 126 42 overestimate overestimate VB cord-354133-11b0d499 126 43 the the DT cord-354133-11b0d499 126 44 CFR CFR NNP cord-354133-11b0d499 126 45 at at IN cord-354133-11b0d499 126 46 later later JJ cord-354133-11b0d499 126 47 times time NNS cord-354133-11b0d499 126 48 ( ( -LRB- cord-354133-11b0d499 126 49 as as RB cord-354133-11b0d499 126 50 well well RB cord-354133-11b0d499 126 51 as as IN cord-354133-11b0d499 126 52 very very RB cord-354133-11b0d499 126 53 early early JJ cord-354133-11b0d499 126 54 times time NNS cord-354133-11b0d499 126 55 ) ) -RRB- cord-354133-11b0d499 126 56 . . . cord-354133-11b0d499 127 1 Further further RB cord-354133-11b0d499 127 2 , , , cord-354133-11b0d499 127 3 this this DT cord-354133-11b0d499 127 4 method method NN cord-354133-11b0d499 127 5 requires require VBZ cord-354133-11b0d499 127 6 the the DT cord-354133-11b0d499 127 7 use use NN cord-354133-11b0d499 127 8 of of IN cord-354133-11b0d499 127 9 parametrised parametrised JJ cord-354133-11b0d499 127 10 data datum NNS cord-354133-11b0d499 127 11 ( ( -LRB- cord-354133-11b0d499 127 12 the the DT cord-354133-11b0d499 127 13 time time NN cord-354133-11b0d499 127 14 distribution distribution NN cord-354133-11b0d499 127 15 for for IN cord-354133-11b0d499 127 16 onset onset NN cord-354133-11b0d499 127 17 to to IN cord-354133-11b0d499 127 18 death death NN cord-354133-11b0d499 127 19 ) ) -RRB- cord-354133-11b0d499 127 20 that that WDT cord-354133-11b0d499 127 21 are be VBP cord-354133-11b0d499 127 22 not not RB cord-354133-11b0d499 127 23 available available JJ cord-354133-11b0d499 127 24 at at IN cord-354133-11b0d499 127 25 the the DT cord-354133-11b0d499 127 26 time time NN cord-354133-11b0d499 127 27 that that WDT cord-354133-11b0d499 127 28 the the DT cord-354133-11b0d499 127 29 predictions prediction NNS cord-354133-11b0d499 127 30 are be VBP cord-354133-11b0d499 127 31 purported purport VBN cord-354133-11b0d499 127 32 to to TO cord-354133-11b0d499 127 33 be be VB cord-354133-11b0d499 127 34 made make VBN cord-354133-11b0d499 127 35 . . . cord-354133-11b0d499 128 1 In in IN cord-354133-11b0d499 128 2 fact fact NN cord-354133-11b0d499 128 3 , , , cord-354133-11b0d499 128 4 when when WRB cord-354133-11b0d499 128 5 Nishiura Nishiura NNP cord-354133-11b0d499 128 6 et et NNP cord-354133-11b0d499 128 7 al al NNP cord-354133-11b0d499 128 8 . . . cord-354133-11b0d499 129 1 [ [ -LRB- cord-354133-11b0d499 129 2 22 22 CD cord-354133-11b0d499 129 3 ] ] -RRB- cord-354133-11b0d499 129 4 apply apply VB cord-354133-11b0d499 129 5 the the DT cord-354133-11b0d499 129 6 method method NN cord-354133-11b0d499 129 7 to to IN cord-354133-11b0d499 129 8 early early JJ cord-354133-11b0d499 129 9 H1N1 H1N1 NNP cord-354133-11b0d499 129 10 ( ( -LRB- cord-354133-11b0d499 129 11 swine swine NNP cord-354133-11b0d499 129 12 flu flu NN cord-354133-11b0d499 129 13 ) ) -RRB- cord-354133-11b0d499 129 14 data datum NNS cord-354133-11b0d499 129 15 in in IN cord-354133-11b0d499 129 16 2009 2009 CD cord-354133-11b0d499 129 17 they -PRON- PRP cord-354133-11b0d499 129 18 are be VBP cord-354133-11b0d499 129 19 forced force VBN cord-354133-11b0d499 129 20 to to TO cord-354133-11b0d499 129 21 use use VB cord-354133-11b0d499 129 22 a a DT cord-354133-11b0d499 129 23 time time NN cord-354133-11b0d499 129 24 distribution distribution NN cord-354133-11b0d499 129 25 calculated calculate VBN cord-354133-11b0d499 129 26 from from IN cord-354133-11b0d499 129 27 historical historical JJ cord-354133-11b0d499 129 28 data datum NNS cord-354133-11b0d499 129 29 for for IN cord-354133-11b0d499 129 30 H1N1 H1N1 NNP cord-354133-11b0d499 129 31 ( ( -LRB- cord-354133-11b0d499 129 32 Spanish Spanish NNP cord-354133-11b0d499 129 33 ) ) -RRB- cord-354133-11b0d499 129 34 influenza influenza NN cord-354133-11b0d499 129 35 from from IN cord-354133-11b0d499 129 36 1918 1918 CD cord-354133-11b0d499 129 37 - - SYM cord-354133-11b0d499 129 38 1919 1919 CD cord-354133-11b0d499 129 39 , , , cord-354133-11b0d499 129 40 which which WDT cord-354133-11b0d499 129 41 is be VBZ cord-354133-11b0d499 129 42 problematic problematic JJ cord-354133-11b0d499 129 43 ; ; : cord-354133-11b0d499 129 44 a a DT cord-354133-11b0d499 129 45 sensitivity sensitivity NN cord-354133-11b0d499 129 46 analysis analysis NN cord-354133-11b0d499 129 47 shows show VBZ cord-354133-11b0d499 129 48 that that IN cord-354133-11b0d499 129 49 the the DT cord-354133-11b0d499 129 50 predicted predict VBN cord-354133-11b0d499 129 51 CFR CFR NNP cord-354133-11b0d499 129 52 is be VBZ cord-354133-11b0d499 129 53 sensitive sensitive JJ cord-354133-11b0d499 129 54 to to IN cord-354133-11b0d499 129 55 the the DT cord-354133-11b0d499 129 56 choice choice NN cord-354133-11b0d499 129 57 of of IN cord-354133-11b0d499 129 58 distribution distribution NN cord-354133-11b0d499 129 59 parameters parameter NNS cord-354133-11b0d499 129 60 , , , cord-354133-11b0d499 129 61 making make VBG cord-354133-11b0d499 129 62 this this DT cord-354133-11b0d499 129 63 method method NN cord-354133-11b0d499 129 64 somewhat somewhat RB cord-354133-11b0d499 129 65 difficult difficult JJ cord-354133-11b0d499 129 66 to to TO cord-354133-11b0d499 129 67 apply apply VB cord-354133-11b0d499 129 68 in in IN cord-354133-11b0d499 129 69 the the DT cord-354133-11b0d499 129 70 circumstances circumstance NNS cord-354133-11b0d499 129 71 for for IN cord-354133-11b0d499 129 72 which which WDT cord-354133-11b0d499 129 73 it -PRON- PRP cord-354133-11b0d499 129 74 is be VBZ cord-354133-11b0d499 129 75 proposed propose VBN cord-354133-11b0d499 129 76 . . . cord-354133-11b0d499 130 1 In in IN cord-354133-11b0d499 130 2 comparison comparison NN cord-354133-11b0d499 130 3 , , , cord-354133-11b0d499 130 4 the the DT cord-354133-11b0d499 130 5 time time NN cord-354133-11b0d499 130 6 - - HYPH cord-354133-11b0d499 130 7 shifted shift VBN cord-354133-11b0d499 130 8 distribution distribution NN cord-354133-11b0d499 130 9 analysis analysis NN cord-354133-11b0d499 130 10 is be VBZ cord-354133-11b0d499 130 11 both both DT cord-354133-11b0d499 130 12 transparent transparent JJ cord-354133-11b0d499 130 13 and and CC cord-354133-11b0d499 130 14 straightforward straightforward JJ cord-354133-11b0d499 130 15 to to TO cord-354133-11b0d499 130 16 implement implement VB cord-354133-11b0d499 130 17 , , , cord-354133-11b0d499 130 18 using use VBG cord-354133-11b0d499 130 19 only only RB cord-354133-11b0d499 130 20 publicly publicly RB cord-354133-11b0d499 130 21 available available JJ cord-354133-11b0d499 130 22 data datum NNS cord-354133-11b0d499 130 23 and and CC cord-354133-11b0d499 130 24 no no DT cord-354133-11b0d499 130 25 assumptions assumption NNS cord-354133-11b0d499 130 26 , , , cord-354133-11b0d499 130 27 and and CC cord-354133-11b0d499 130 28 can can MD cord-354133-11b0d499 130 29 provide provide VB cord-354133-11b0d499 130 30 a a DT cord-354133-11b0d499 130 31 reasonably reasonably RB cord-354133-11b0d499 130 32 early early JJ cord-354133-11b0d499 130 33 estimate estimate NN cord-354133-11b0d499 130 34 ( ( -LRB- cord-354133-11b0d499 130 35 once once RB cord-354133-11b0d499 130 36 exponential exponential JJ cord-354133-11b0d499 130 37 growth growth NN cord-354133-11b0d499 130 38 has have VBZ cord-354133-11b0d499 130 39 sufficiently sufficiently RB cord-354133-11b0d499 130 40 slowed slow VBN cord-354133-11b0d499 130 41 ) ) -RRB- cord-354133-11b0d499 130 42 of of IN cord-354133-11b0d499 130 43 CFR CFR NNP cord-354133-11b0d499 130 44 that that WDT cord-354133-11b0d499 130 45 converges converge VBZ cord-354133-11b0d499 130 46 to to IN cord-354133-11b0d499 130 47 the the DT cord-354133-11b0d499 130 48 " " `` cord-354133-11b0d499 130 49 true true JJ cord-354133-11b0d499 130 50 " " '' cord-354133-11b0d499 130 51 value value NN cord-354133-11b0d499 130 52 . . . cord-354133-11b0d499 131 1 If if IN cord-354133-11b0d499 131 2 the the DT cord-354133-11b0d499 131 3 value value NN cord-354133-11b0d499 131 4 of of IN cord-354133-11b0d499 131 5 the the DT cord-354133-11b0d499 131 6 time time NN cord-354133-11b0d499 131 7 delay delay NN cord-354133-11b0d499 131 8 is be VBZ cord-354133-11b0d499 131 9 approximately approximately RB cord-354133-11b0d499 131 10 known know VBN cord-354133-11b0d499 131 11 early early RB cord-354133-11b0d499 131 12 in in IN cord-354133-11b0d499 131 13 the the DT cord-354133-11b0d499 131 14 outbreak outbreak NN cord-354133-11b0d499 131 15 , , , cord-354133-11b0d499 131 16 this this DT cord-354133-11b0d499 131 17 could could MD cord-354133-11b0d499 131 18 be be VB cord-354133-11b0d499 131 19 used use VBN cord-354133-11b0d499 131 20 to to TO cord-354133-11b0d499 131 21 constrain constrain VB cord-354133-11b0d499 131 22 the the DT cord-354133-11b0d499 131 23 fitting fitting JJ cord-354133-11b0d499 131 24 procedure procedure NN cord-354133-11b0d499 131 25 , , , cord-354133-11b0d499 131 26 but but CC cord-354133-11b0d499 131 27 as as IN cord-354133-11b0d499 131 28 observed observe VBD cord-354133-11b0d499 131 29 already already RB cord-354133-11b0d499 131 30 , , , cord-354133-11b0d499 131 31 it -PRON- PRP cord-354133-11b0d499 131 32 is be VBZ cord-354133-11b0d499 131 33 difficult difficult JJ cord-354133-11b0d499 131 34 either either CC cord-354133-11b0d499 131 35 to to TO cord-354133-11b0d499 131 36 know know VB cord-354133-11b0d499 131 37 the the DT cord-354133-11b0d499 131 38 time time NN cord-354133-11b0d499 131 39 delay delay NN cord-354133-11b0d499 131 40 between between IN cord-354133-11b0d499 131 41 onset onset NN cord-354133-11b0d499 131 42 and and CC cord-354133-11b0d499 131 43 death death NN cord-354133-11b0d499 131 44 or or CC cord-354133-11b0d499 131 45 to to TO cord-354133-11b0d499 131 46 apply apply VB cord-354133-11b0d499 131 47 it -PRON- PRP cord-354133-11b0d499 131 48 to to IN cord-354133-11b0d499 131 49 the the DT cord-354133-11b0d499 131 50 time time NN cord-354133-11b0d499 131 51 delay delay NN cord-354133-11b0d499 131 52 between between IN cord-354133-11b0d499 131 53 reporting reporting NN cord-354133-11b0d499 131 54 of of IN cord-354133-11b0d499 131 55 cases case NNS cord-354133-11b0d499 131 56 and and CC cord-354133-11b0d499 131 57 deaths death NNS cord-354133-11b0d499 131 58 . . . cord-354133-11b0d499 132 1 Time time NN cord-354133-11b0d499 132 2 - - HYPH cord-354133-11b0d499 132 3 shifted shift VBN cord-354133-11b0d499 132 4 distribution distribution NN cord-354133-11b0d499 132 5 analysis analysis NN cord-354133-11b0d499 132 6 was be VBD cord-354133-11b0d499 132 7 performed perform VBN cord-354133-11b0d499 132 8 on on IN cord-354133-11b0d499 132 9 COVID-19 COVID-19 NNP cord-354133-11b0d499 132 10 data datum NNS cord-354133-11b0d499 132 11 from from IN cord-354133-11b0d499 132 12 an an DT cord-354133-11b0d499 132 13 extensive extensive JJ cord-354133-11b0d499 132 14 range range NN cord-354133-11b0d499 132 15 of of IN cord-354133-11b0d499 132 16 countries country NNS cord-354133-11b0d499 132 17 , , , cord-354133-11b0d499 132 18 using use VBG cord-354133-11b0d499 132 19 datasets dataset NNS cord-354133-11b0d499 132 20 from from IN cord-354133-11b0d499 132 21 Johns Johns NNP cord-354133-11b0d499 132 22 Hopkins Hopkins NNP cord-354133-11b0d499 132 23 Center Center NNP cord-354133-11b0d499 132 24 for for IN cord-354133-11b0d499 132 25 Systems Systems NNP cord-354133-11b0d499 132 26 Science Science NNP cord-354133-11b0d499 132 27 and and CC cord-354133-11b0d499 132 28 Engineering Engineering NNP cord-354133-11b0d499 132 29 [ [ -LRB- cord-354133-11b0d499 132 30 14 14 CD cord-354133-11b0d499 132 31 ] ] -RRB- cord-354133-11b0d499 132 32 , , , cord-354133-11b0d499 132 33 cross cross NN cord-354133-11b0d499 132 34 - - VBN cord-354133-11b0d499 132 35 checked check VBN cord-354133-11b0d499 132 36 and and CC cord-354133-11b0d499 132 37 supplemented supplement VBN cord-354133-11b0d499 132 38 with with IN cord-354133-11b0d499 132 39 data datum NNS cord-354133-11b0d499 132 40 from from IN cord-354133-11b0d499 132 41 Worldometers.com worldometers.com NN cord-354133-11b0d499 132 42 and and CC cord-354133-11b0d499 132 43 3-day 3-day NN cord-354133-11b0d499 132 44 averaged average VBD cord-354133-11b0d499 132 45 . . . cord-354133-11b0d499 133 1 For for IN cord-354133-11b0d499 133 2 most most JJS cord-354133-11b0d499 133 3 countries country NNS cord-354133-11b0d499 133 4 ( ( -LRB- cord-354133-11b0d499 133 5 as as IN cord-354133-11b0d499 133 6 for for IN cord-354133-11b0d499 133 7 Italy Italy NNP cord-354133-11b0d499 133 8 ) ) -RRB- cord-354133-11b0d499 133 9 , , , cord-354133-11b0d499 133 10 the the DT cord-354133-11b0d499 133 11 analysis analysis NN cord-354133-11b0d499 133 12 results result VBZ cord-354133-11b0d499 133 13 in in IN cord-354133-11b0d499 133 14 a a DT cord-354133-11b0d499 133 15 robust robust JJ cord-354133-11b0d499 133 16 linear linear JJ cord-354133-11b0d499 133 17 fit fit NN cord-354133-11b0d499 133 18 and and CC cord-354133-11b0d499 133 19 provides provide VBZ cord-354133-11b0d499 133 20 a a DT cord-354133-11b0d499 133 21 stable stable JJ cord-354133-11b0d499 133 22 estimate estimate NN cord-354133-11b0d499 133 23 for for IN cord-354133-11b0d499 133 24 CFR CFR NNP cord-354133-11b0d499 133 25 and and CC cord-354133-11b0d499 133 26 delay delay NN cord-354133-11b0d499 133 27 time time NN cord-354133-11b0d499 133 28 . . . cord-354133-11b0d499 134 1 These these DT cord-354133-11b0d499 134 2 data datum NNS cord-354133-11b0d499 134 3 are be VBP cord-354133-11b0d499 134 4 shown show VBN cord-354133-11b0d499 134 5 in in IN cord-354133-11b0d499 134 6 Table Table NNP cord-354133-11b0d499 134 7 1 1 CD cord-354133-11b0d499 134 8 , , , cord-354133-11b0d499 134 9 organised organise VBN cord-354133-11b0d499 134 10 by by IN cord-354133-11b0d499 134 11 region region NN cord-354133-11b0d499 134 12 is be VBZ cord-354133-11b0d499 134 13 the the DT cord-354133-11b0d499 134 14 author author NN cord-354133-11b0d499 134 15 / / SYM cord-354133-11b0d499 134 16 funder funder NN cord-354133-11b0d499 134 17 , , , cord-354133-11b0d499 134 18 who who WP cord-354133-11b0d499 134 19 has have VBZ cord-354133-11b0d499 134 20 granted grant VBN cord-354133-11b0d499 134 21 medRxiv medRxiv NNS cord-354133-11b0d499 134 22 a a DT cord-354133-11b0d499 134 23 license license NN cord-354133-11b0d499 134 24 to to TO cord-354133-11b0d499 134 25 display display VB cord-354133-11b0d499 134 26 the the DT cord-354133-11b0d499 134 27 preprint preprint NN cord-354133-11b0d499 134 28 in in IN cord-354133-11b0d499 134 29 ( ( -LRB- cord-354133-11b0d499 134 30 which which WDT cord-354133-11b0d499 134 31 was be VBD cord-354133-11b0d499 134 32 not not RB cord-354133-11b0d499 134 33 certified certify VBN cord-354133-11b0d499 134 34 by by IN cord-354133-11b0d499 134 35 peer peer NN cord-354133-11b0d499 134 36 review review NN cord-354133-11b0d499 134 37 ) ) -RRB- cord-354133-11b0d499 134 38 preprint preprint NN cord-354133-11b0d499 135 1 The the DT cord-354133-11b0d499 135 2 copyright copyright NN cord-354133-11b0d499 135 3 holder holder NN cord-354133-11b0d499 135 4 for for IN cord-354133-11b0d499 135 5 this this DT cord-354133-11b0d499 135 6 this this DT cord-354133-11b0d499 135 7 version version NN cord-354133-11b0d499 135 8 posted post VBD cord-354133-11b0d499 135 9 October October NNP cord-354133-11b0d499 135 10 27 27 CD cord-354133-11b0d499 135 11 , , , cord-354133-11b0d499 135 12 2020 2020 CD cord-354133-11b0d499 135 13 . . . cord-354133-11b0d499 136 1 Table table NN cord-354133-11b0d499 136 2 1 1 CD cord-354133-11b0d499 136 3 , , , cord-354133-11b0d499 136 4 most most JJS cord-354133-11b0d499 136 5 analyses analysis NNS cord-354133-11b0d499 136 6 use use VBP cord-354133-11b0d499 136 7 data datum NNS cord-354133-11b0d499 136 8 up up IN cord-354133-11b0d499 136 9 until until IN cord-354133-11b0d499 136 10 the the DT cord-354133-11b0d499 136 11 end end NN cord-354133-11b0d499 136 12 of of IN cord-354133-11b0d499 136 13 May May NNP cord-354133-11b0d499 136 14 , , , cord-354133-11b0d499 136 15 which which WDT cord-354133-11b0d499 136 16 is be VBZ cord-354133-11b0d499 136 17 generally generally RB cord-354133-11b0d499 136 18 representative representative JJ cord-354133-11b0d499 136 19 of of IN cord-354133-11b0d499 136 20 the the DT cord-354133-11b0d499 136 21 initial initial JJ cord-354133-11b0d499 136 22 outbreak outbreak NN cord-354133-11b0d499 136 23 ; ; : cord-354133-11b0d499 136 24 for for IN cord-354133-11b0d499 136 25 some some DT cord-354133-11b0d499 136 26 countries country NNS cord-354133-11b0d499 136 27 with with IN cord-354133-11b0d499 136 28 later later JJ cord-354133-11b0d499 136 29 outbreaks outbreak NNS cord-354133-11b0d499 136 30 , , , cord-354133-11b0d499 136 31 later later RB cord-354133-11b0d499 136 32 end end NN cord-354133-11b0d499 136 33 dates date NNS cord-354133-11b0d499 136 34 are be VBP cord-354133-11b0d499 136 35 used use VBN cord-354133-11b0d499 136 36 . . . cord-354133-11b0d499 137 1 In in IN cord-354133-11b0d499 137 2 many many JJ cord-354133-11b0d499 137 3 countries country NNS cord-354133-11b0d499 137 4 , , , cord-354133-11b0d499 137 5 more more RBR cord-354133-11b0d499 137 6 recent recent JJ cord-354133-11b0d499 137 7 outbreaks outbreak NNS cord-354133-11b0d499 137 8 have have VBP cord-354133-11b0d499 137 9 had have VBN cord-354133-11b0d499 137 10 dramatically dramatically RB cord-354133-11b0d499 137 11 different different JJ cord-354133-11b0d499 137 12 CFR CFR NNP cord-354133-11b0d499 137 13 values value NNS cord-354133-11b0d499 137 14 to to IN cord-354133-11b0d499 137 15 initial initial JJ cord-354133-11b0d499 137 16 outbreaks outbreak NNS cord-354133-11b0d499 137 17 ( ( -LRB- cord-354133-11b0d499 137 18 due due JJ cord-354133-11b0d499 137 19 largely largely RB cord-354133-11b0d499 137 20 to to IN cord-354133-11b0d499 137 21 improved improve VBN cord-354133-11b0d499 137 22 testing testing NN cord-354133-11b0d499 137 23 rates rate NNS cord-354133-11b0d499 137 24 ) ) -RRB- cord-354133-11b0d499 137 25 ; ; : cord-354133-11b0d499 137 26 these these DT cord-354133-11b0d499 137 27 can can MD cord-354133-11b0d499 137 28 be be VB cord-354133-11b0d499 137 29 analysed analyse VBN cord-354133-11b0d499 137 30 independently independently RB cord-354133-11b0d499 137 31 by by IN cord-354133-11b0d499 137 32 selecting select VBG cord-354133-11b0d499 137 33 the the DT cord-354133-11b0d499 137 34 time time NN cord-354133-11b0d499 137 35 frame frame NN cord-354133-11b0d499 137 36 studied study VBD cord-354133-11b0d499 137 37 , , , cord-354133-11b0d499 137 38 but but CC cord-354133-11b0d499 137 39 values value NNS cord-354133-11b0d499 137 40 presented present VBN cord-354133-11b0d499 137 41 here here RB cord-354133-11b0d499 137 42 are be VBP cord-354133-11b0d499 137 43 for for IN cord-354133-11b0d499 137 44 the the DT cord-354133-11b0d499 137 45 initial initial JJ cord-354133-11b0d499 137 46 outbreak outbreak NN cord-354133-11b0d499 137 47 in in IN cord-354133-11b0d499 137 48 each each DT cord-354133-11b0d499 137 49 country country NN cord-354133-11b0d499 137 50 . . . cord-354133-11b0d499 138 1 The the DT cord-354133-11b0d499 138 2 most most RBS cord-354133-11b0d499 138 3 notable notable JJ cord-354133-11b0d499 138 4 result result NN cord-354133-11b0d499 138 5 is be VBZ cord-354133-11b0d499 138 6 the the DT cord-354133-11b0d499 138 7 huge huge JJ cord-354133-11b0d499 138 8 range range NN cord-354133-11b0d499 138 9 in in IN cord-354133-11b0d499 138 10 both both DT cord-354133-11b0d499 138 11 delay delay NN cord-354133-11b0d499 138 12 times time NNS cord-354133-11b0d499 138 13 and and CC cord-354133-11b0d499 138 14 calculated calculate VBD cord-354133-11b0d499 138 15 CFR CFR NNP cord-354133-11b0d499 138 16 estimates estimate NNS cord-354133-11b0d499 138 17 over over IN cord-354133-11b0d499 138 18 different different JJ cord-354133-11b0d499 138 19 countries country NNS cord-354133-11b0d499 138 20 : : : cord-354133-11b0d499 138 21 from from IN cord-354133-11b0d499 138 22 zero zero CD cord-354133-11b0d499 138 23 to to IN cord-354133-11b0d499 138 24 24 24 CD cord-354133-11b0d499 138 25 days day NNS cord-354133-11b0d499 138 26 ' ' POS cord-354133-11b0d499 138 27 delay delay NN cord-354133-11b0d499 138 28 and and CC cord-354133-11b0d499 138 29 from from IN cord-354133-11b0d499 138 30 less less JJR cord-354133-11b0d499 138 31 than than IN cord-354133-11b0d499 138 32 one one CD cord-354133-11b0d499 138 33 to to TO cord-354133-11b0d499 138 34 20 20 CD cord-354133-11b0d499 138 35 % % NN cord-354133-11b0d499 138 36 case case NN cord-354133-11b0d499 138 37 fatality fatality NN cord-354133-11b0d499 138 38 ratio ratio NN cord-354133-11b0d499 138 39 . . . cord-354133-11b0d499 139 1 The the DT cord-354133-11b0d499 139 2 highest high JJS cord-354133-11b0d499 139 3 ratios ratio NNS cord-354133-11b0d499 139 4 are be VBP cord-354133-11b0d499 139 5 calculated calculate VBN cord-354133-11b0d499 139 6 in in IN cord-354133-11b0d499 139 7 Western Western NNP cord-354133-11b0d499 139 8 Europe Europe NNP cord-354133-11b0d499 139 9 ( ( -LRB- cord-354133-11b0d499 139 10 up up IN cord-354133-11b0d499 139 11 to to TO cord-354133-11b0d499 139 12 20 20 CD cord-354133-11b0d499 139 13 % % NN cord-354133-11b0d499 139 14 ) ) -RRB- cord-354133-11b0d499 139 15 , , , cord-354133-11b0d499 139 16 followed follow VBN cord-354133-11b0d499 139 17 by by IN cord-354133-11b0d499 139 18 North North NNP cord-354133-11b0d499 139 19 America America NNP cord-354133-11b0d499 139 20 ( ( -LRB- cord-354133-11b0d499 139 21 up up IN cord-354133-11b0d499 139 22 to to TO cord-354133-11b0d499 139 23 15 15 CD cord-354133-11b0d499 139 24 % % NN cord-354133-11b0d499 139 25 ) ) -RRB- cord-354133-11b0d499 139 26 , , , cord-354133-11b0d499 139 27 South South NNP cord-354133-11b0d499 139 28 America America NNP cord-354133-11b0d499 139 29 ( ( -LRB- cord-354133-11b0d499 139 30 up up IN cord-354133-11b0d499 139 31 to to TO cord-354133-11b0d499 139 32 10 10 CD cord-354133-11b0d499 139 33 % % NN cord-354133-11b0d499 139 34 ) ) -RRB- cord-354133-11b0d499 139 35 , , , cord-354133-11b0d499 139 36 Africa Africa NNP cord-354133-11b0d499 139 37 ( ( -LRB- cord-354133-11b0d499 139 38 up up IN cord-354133-11b0d499 139 39 to to TO cord-354133-11b0d499 139 40 7 7 CD cord-354133-11b0d499 139 41 % % NN cord-354133-11b0d499 139 42 ) ) -RRB- cord-354133-11b0d499 139 43 , , , cord-354133-11b0d499 139 44 and and CC cord-354133-11b0d499 139 45 lowest low JJS cord-354133-11b0d499 139 46 in in IN cord-354133-11b0d499 139 47 the the DT cord-354133-11b0d499 139 48 Middle Middle NNP cord-354133-11b0d499 139 49 East East NNP cord-354133-11b0d499 139 50 , , , cord-354133-11b0d499 139 51 Asia Asia NNP cord-354133-11b0d499 139 52 and and CC cord-354133-11b0d499 139 53 Oceania Oceania NNP cord-354133-11b0d499 139 54 ( ( -LRB- cord-354133-11b0d499 139 55 up up IN cord-354133-11b0d499 139 56 to to TO cord-354133-11b0d499 139 57 5 5 CD cord-354133-11b0d499 139 58 % % NN cord-354133-11b0d499 139 59 ) ) -RRB- cord-354133-11b0d499 139 60 . . . cord-354133-11b0d499 140 1 It -PRON- PRP cord-354133-11b0d499 140 2 is be VBZ cord-354133-11b0d499 140 3 problematic problematic JJ cord-354133-11b0d499 140 4 to to TO cord-354133-11b0d499 140 5 draw draw VB cord-354133-11b0d499 140 6 conclusions conclusion NNS cord-354133-11b0d499 140 7 about about IN cord-354133-11b0d499 140 8 relative relative JJ cord-354133-11b0d499 140 9 COVID-19 covid-19 JJ cord-354133-11b0d499 140 10 virulence virulence NN cord-354133-11b0d499 140 11 by by IN cord-354133-11b0d499 140 12 comparing compare VBG cord-354133-11b0d499 140 13 CFR CFR NNP cord-354133-11b0d499 140 14 values value NNS cord-354133-11b0d499 140 15 between between IN cord-354133-11b0d499 140 16 countries country NNS cord-354133-11b0d499 140 17 , , , cord-354133-11b0d499 140 18 because because IN cord-354133-11b0d499 140 19 of of IN cord-354133-11b0d499 140 20 vast vast JJ cord-354133-11b0d499 140 21 differences difference NNS cord-354133-11b0d499 140 22 in in IN cord-354133-11b0d499 140 23 testing testing NN cord-354133-11b0d499 140 24 and and CC cord-354133-11b0d499 140 25 reporting reporting NN cord-354133-11b0d499 140 26 regimes regime NNS cord-354133-11b0d499 140 27 -in -in VBZ cord-354133-11b0d499 140 28 particular particular JJ cord-354133-11b0d499 140 29 , , , cord-354133-11b0d499 140 30 the the DT cord-354133-11b0d499 140 31 under under NN cord-354133-11b0d499 140 32 - - HYPH cord-354133-11b0d499 140 33 reporting reporting NN cord-354133-11b0d499 140 34 of of IN cord-354133-11b0d499 140 35 cases case NNS cord-354133-11b0d499 140 36 ( ( -LRB- cord-354133-11b0d499 140 37 including include VBG cord-354133-11b0d499 140 38 mild mild JJ cord-354133-11b0d499 140 39 or or CC cord-354133-11b0d499 140 40 asymptomatic asymptomatic JJ cord-354133-11b0d499 140 41 cases case NNS cord-354133-11b0d499 140 42 ) ) -RRB- cord-354133-11b0d499 140 43 due due IN cord-354133-11b0d499 140 44 to to IN cord-354133-11b0d499 140 45 inadequate inadequate JJ cord-354133-11b0d499 140 46 testing testing NN cord-354133-11b0d499 140 47 , , , cord-354133-11b0d499 140 48 but but CC cord-354133-11b0d499 140 49 also also RB cord-354133-11b0d499 140 50 differences difference NNS cord-354133-11b0d499 140 51 in in IN cord-354133-11b0d499 140 52 classification classification NN cord-354133-11b0d499 140 53 or or CC cord-354133-11b0d499 140 54 recognition recognition NN cord-354133-11b0d499 140 55 of of IN cord-354133-11b0d499 140 56 COVID-19-related covid-19-related JJ cord-354133-11b0d499 140 57 deaths death NNS cord-354133-11b0d499 140 58 . . . cord-354133-11b0d499 141 1 However however RB cord-354133-11b0d499 141 2 , , , cord-354133-11b0d499 141 3 it -PRON- PRP cord-354133-11b0d499 141 4 is be VBZ cord-354133-11b0d499 141 5 instructive instructive JJ cord-354133-11b0d499 141 6 to to TO cord-354133-11b0d499 141 7 calculate calculate VB cord-354133-11b0d499 141 8 in in IN cord-354133-11b0d499 141 9 this this DT cord-354133-11b0d499 141 10 way way NN cord-354133-11b0d499 141 11 , , , cord-354133-11b0d499 141 12 for for IN cord-354133-11b0d499 141 13 any any DT cord-354133-11b0d499 141 14 given give VBN cord-354133-11b0d499 141 15 country country NN cord-354133-11b0d499 141 16 , , , cord-354133-11b0d499 141 17 the the DT cord-354133-11b0d499 141 18 proportion proportion NN cord-354133-11b0d499 141 19 of of IN cord-354133-11b0d499 141 20 detected detect VBN cord-354133-11b0d499 141 21 cases case NNS cord-354133-11b0d499 141 22 that that WDT cord-354133-11b0d499 141 23 are be VBP cord-354133-11b0d499 141 24 currently currently RB cord-354133-11b0d499 141 25 proving prove VBG cord-354133-11b0d499 141 26 fatal fatal JJ cord-354133-11b0d499 141 27 , , , cord-354133-11b0d499 141 28 for for IN cord-354133-11b0d499 141 29 the the DT cord-354133-11b0d499 141 30 purposes purpose NNS cord-354133-11b0d499 141 31 of of IN cord-354133-11b0d499 141 32 public public JJ cord-354133-11b0d499 141 33 health health NN cord-354133-11b0d499 141 34 management management NN cord-354133-11b0d499 141 35 and and CC cord-354133-11b0d499 141 36 planning planning NN cord-354133-11b0d499 141 37 . . . cord-354133-11b0d499 142 1 For for IN cord-354133-11b0d499 142 2 comparison comparison NN cord-354133-11b0d499 142 3 , , , cord-354133-11b0d499 142 4 Mazumder Mazumder NNP cord-354133-11b0d499 142 5 and and CC cord-354133-11b0d499 142 6 colleagues colleague NNS cord-354133-11b0d499 142 7 [ [ -LRB- cord-354133-11b0d499 142 8 8 8 CD cord-354133-11b0d499 142 9 ] ] -RRB- cord-354133-11b0d499 142 10 calculated calculate VBN cord-354133-11b0d499 142 11 case case NN cord-354133-11b0d499 142 12 fatality fatality NN cord-354133-11b0d499 142 13 ratios ratio NNS cord-354133-11b0d499 142 14 for for IN cord-354133-11b0d499 142 15 a a DT cord-354133-11b0d499 142 16 range range NN cord-354133-11b0d499 142 17 of of IN cord-354133-11b0d499 142 18 countries country NNS cord-354133-11b0d499 142 19 using use VBG cord-354133-11b0d499 142 20 recovery recovery NN cord-354133-11b0d499 142 21 and and CC cord-354133-11b0d499 142 22 death death NN cord-354133-11b0d499 142 23 is be VBZ cord-354133-11b0d499 142 24 the the DT cord-354133-11b0d499 142 25 author author NN cord-354133-11b0d499 142 26 / / SYM cord-354133-11b0d499 142 27 funder funder NN cord-354133-11b0d499 142 28 , , , cord-354133-11b0d499 142 29 who who WP cord-354133-11b0d499 142 30 has have VBZ cord-354133-11b0d499 142 31 granted grant VBN cord-354133-11b0d499 142 32 medRxiv medRxiv NNS cord-354133-11b0d499 142 33 a a DT cord-354133-11b0d499 142 34 license license NN cord-354133-11b0d499 142 35 to to TO cord-354133-11b0d499 142 36 display display VB cord-354133-11b0d499 142 37 the the DT cord-354133-11b0d499 142 38 preprint preprint NN cord-354133-11b0d499 142 39 in in IN cord-354133-11b0d499 142 40 ( ( -LRB- cord-354133-11b0d499 142 41 which which WDT cord-354133-11b0d499 142 42 was be VBD cord-354133-11b0d499 142 43 not not RB cord-354133-11b0d499 142 44 certified certify VBN cord-354133-11b0d499 142 45 by by IN cord-354133-11b0d499 142 46 peer peer NN cord-354133-11b0d499 142 47 review review NN cord-354133-11b0d499 142 48 ) ) -RRB- cord-354133-11b0d499 143 1 preprint preprint NN cord-354133-11b0d499 144 1 The the DT cord-354133-11b0d499 144 2 copyright copyright NN cord-354133-11b0d499 144 3 holder holder NN cord-354133-11b0d499 144 4 for for IN cord-354133-11b0d499 144 5 this this DT cord-354133-11b0d499 144 6 this this DT cord-354133-11b0d499 144 7 version version NN cord-354133-11b0d499 144 8 posted post VBD cord-354133-11b0d499 144 9 October October NNP cord-354133-11b0d499 144 10 27 27 CD cord-354133-11b0d499 144 11 , , , cord-354133-11b0d499 144 12 2020 2020 CD cord-354133-11b0d499 144 13 . . . cord-354133-11b0d499 145 1 ; ; : cord-354133-11b0d499 145 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 145 3 doi doi NN cord-354133-11b0d499 145 4 : : : cord-354133-11b0d499 146 1 medRxiv medRxiv NNP cord-354133-11b0d499 146 2 preprint preprint NN cord-354133-11b0d499 146 3 is be VBZ cord-354133-11b0d499 146 4 the the DT cord-354133-11b0d499 146 5 author author NN cord-354133-11b0d499 146 6 / / SYM cord-354133-11b0d499 146 7 funder funder NN cord-354133-11b0d499 146 8 , , , cord-354133-11b0d499 146 9 who who WP cord-354133-11b0d499 146 10 has have VBZ cord-354133-11b0d499 146 11 granted grant VBN cord-354133-11b0d499 146 12 medRxiv medRxiv NNS cord-354133-11b0d499 146 13 a a DT cord-354133-11b0d499 146 14 license license NN cord-354133-11b0d499 146 15 to to TO cord-354133-11b0d499 146 16 display display VB cord-354133-11b0d499 146 17 the the DT cord-354133-11b0d499 146 18 preprint preprint NN cord-354133-11b0d499 146 19 in in IN cord-354133-11b0d499 146 20 ( ( -LRB- cord-354133-11b0d499 146 21 which which WDT cord-354133-11b0d499 146 22 was be VBD cord-354133-11b0d499 146 23 not not RB cord-354133-11b0d499 146 24 certified certify VBN cord-354133-11b0d499 146 25 by by IN cord-354133-11b0d499 146 26 peer peer NN cord-354133-11b0d499 146 27 review review NN cord-354133-11b0d499 146 28 ) ) -RRB- cord-354133-11b0d499 147 1 preprint preprint NN cord-354133-11b0d499 147 2 is be VBZ cord-354133-11b0d499 147 3 the the DT cord-354133-11b0d499 147 4 author author NN cord-354133-11b0d499 147 5 / / SYM cord-354133-11b0d499 147 6 funder funder NN cord-354133-11b0d499 147 7 , , , cord-354133-11b0d499 147 8 who who WP cord-354133-11b0d499 147 9 has have VBZ cord-354133-11b0d499 147 10 granted grant VBN cord-354133-11b0d499 147 11 medRxiv medRxiv NNS cord-354133-11b0d499 147 12 a a DT cord-354133-11b0d499 147 13 license license NN cord-354133-11b0d499 147 14 to to TO cord-354133-11b0d499 147 15 display display VB cord-354133-11b0d499 147 16 the the DT cord-354133-11b0d499 147 17 preprint preprint NN cord-354133-11b0d499 147 18 in in IN cord-354133-11b0d499 147 19 ( ( -LRB- cord-354133-11b0d499 147 20 which which WDT cord-354133-11b0d499 147 21 was be VBD cord-354133-11b0d499 147 22 not not RB cord-354133-11b0d499 147 23 certified certify VBN cord-354133-11b0d499 147 24 by by IN cord-354133-11b0d499 147 25 peer peer NN cord-354133-11b0d499 147 26 review review NN cord-354133-11b0d499 147 27 ) ) -RRB- cord-354133-11b0d499 148 1 preprint preprint NN cord-354133-11b0d499 148 2 data datum NNS cord-354133-11b0d499 148 3 from from IN cord-354133-11b0d499 148 4 closed closed JJ cord-354133-11b0d499 148 5 cases case NNS cord-354133-11b0d499 148 6 . . . cord-354133-11b0d499 149 1 They -PRON- PRP cord-354133-11b0d499 149 2 analysed analyse VBD cord-354133-11b0d499 149 3 eleven eleven CD cord-354133-11b0d499 149 4 countries country NNS cord-354133-11b0d499 149 5 with with IN cord-354133-11b0d499 149 6 high high JJ cord-354133-11b0d499 149 7 outcome outcome NN cord-354133-11b0d499 149 8 rates rate NNS cord-354133-11b0d499 149 9 and and CC cord-354133-11b0d499 149 10 sufficient sufficient JJ cord-354133-11b0d499 149 11 progression progression NN cord-354133-11b0d499 149 12 in in IN cord-354133-11b0d499 149 13 the the DT cord-354133-11b0d499 149 14 outbreak outbreak NN cord-354133-11b0d499 149 15 for for IN cord-354133-11b0d499 149 16 analysis analysis NN cord-354133-11b0d499 149 17 ( ( -LRB- cord-354133-11b0d499 149 18 at at IN cord-354133-11b0d499 149 19 the the DT cord-354133-11b0d499 149 20 end end NN cord-354133-11b0d499 149 21 of of IN cord-354133-11b0d499 149 22 April April NNP cord-354133-11b0d499 149 23 ) ) -RRB- cord-354133-11b0d499 149 24 , , , cord-354133-11b0d499 149 25 but but CC cord-354133-11b0d499 149 26 many many JJ cord-354133-11b0d499 149 27 of of IN cord-354133-11b0d499 149 28 their -PRON- PRP$ cord-354133-11b0d499 149 29 calculated calculate VBN cord-354133-11b0d499 149 30 CFR CFR NNP cord-354133-11b0d499 149 31 values value NNS cord-354133-11b0d499 149 32 are be VBP cord-354133-11b0d499 149 33 much much RB cord-354133-11b0d499 149 34 higher high JJR cord-354133-11b0d499 149 35 than than IN cord-354133-11b0d499 149 36 our -PRON- PRP$ cord-354133-11b0d499 149 37 estimates estimate NNS cord-354133-11b0d499 149 38 -for -for : cord-354133-11b0d499 149 39 example example NN cord-354133-11b0d499 149 40 , , , cord-354133-11b0d499 149 41 estimated estimate VBD cord-354133-11b0d499 149 42 CFR CFR NNP cord-354133-11b0d499 149 43 above above IN cord-354133-11b0d499 149 44 30 30 CD cord-354133-11b0d499 149 45 % % NN cord-354133-11b0d499 149 46 for for IN cord-354133-11b0d499 149 47 Italy Italy NNP cord-354133-11b0d499 149 48 , , , cord-354133-11b0d499 149 49 France France NNP cord-354133-11b0d499 149 50 and and CC cord-354133-11b0d499 149 51 USA USA NNP cord-354133-11b0d499 149 52 at at IN cord-354133-11b0d499 149 53 the the DT cord-354133-11b0d499 149 54 end end NN cord-354133-11b0d499 149 55 of of IN cord-354133-11b0d499 149 56 April April NNP cord-354133-11b0d499 149 57 -probably -probably NN cord-354133-11b0d499 149 58 due due JJ cord-354133-11b0d499 149 59 to to IN cord-354133-11b0d499 149 60 delays delay NNS cord-354133-11b0d499 149 61 in in IN cord-354133-11b0d499 149 62 recovery recovery NN cord-354133-11b0d499 149 63 reporting reporting NN cord-354133-11b0d499 149 64 , , , cord-354133-11b0d499 149 65 whereas whereas IN cord-354133-11b0d499 149 66 estimated estimate VBN cord-354133-11b0d499 149 67 CFR CFR NNP cord-354133-11b0d499 149 68 values value NNS cord-354133-11b0d499 149 69 for for IN cord-354133-11b0d499 149 70 Germany Germany NNP cord-354133-11b0d499 149 71 , , , cord-354133-11b0d499 149 72 China China NNP cord-354133-11b0d499 149 73 and and CC cord-354133-11b0d499 149 74 South South NNP cord-354133-11b0d499 149 75 Korea Korea NNP cord-354133-11b0d499 149 76 match match VBP cord-354133-11b0d499 149 77 ours -PRON- PRP cord-354133-11b0d499 149 78 . . . cord-354133-11b0d499 150 1 The the DT cord-354133-11b0d499 150 2 TSD TSD NNP cord-354133-11b0d499 150 3 analysis analysis NN cord-354133-11b0d499 150 4 provides provide VBZ cord-354133-11b0d499 150 5 more more RBR cord-354133-11b0d499 150 6 reliable reliable JJ cord-354133-11b0d499 150 7 estimates estimate NNS cord-354133-11b0d499 150 8 for for IN cord-354133-11b0d499 150 9 a a DT cord-354133-11b0d499 150 10 broader broad JJR cord-354133-11b0d499 150 11 range range NN cord-354133-11b0d499 150 12 of of IN cord-354133-11b0d499 150 13 countries country NNS cord-354133-11b0d499 150 14 , , , cord-354133-11b0d499 150 15 due due IN cord-354133-11b0d499 150 16 to to IN cord-354133-11b0d499 150 17 the the DT cord-354133-11b0d499 150 18 greater great JJR cord-354133-11b0d499 150 19 availability availability NN cord-354133-11b0d499 150 20 of of IN cord-354133-11b0d499 150 21 death death NN cord-354133-11b0d499 150 22 and and CC cord-354133-11b0d499 150 23 case case NN cord-354133-11b0d499 150 24 data datum NNS cord-354133-11b0d499 150 25 over over IN cord-354133-11b0d499 150 26 recovery recovery NN cord-354133-11b0d499 150 27 data datum NNS cord-354133-11b0d499 150 28 . . . cord-354133-11b0d499 151 1 is be VBZ cord-354133-11b0d499 151 2 the the DT cord-354133-11b0d499 151 3 author author NN cord-354133-11b0d499 151 4 / / SYM cord-354133-11b0d499 151 5 funder funder NN cord-354133-11b0d499 151 6 , , , cord-354133-11b0d499 151 7 who who WP cord-354133-11b0d499 151 8 has have VBZ cord-354133-11b0d499 151 9 granted grant VBN cord-354133-11b0d499 151 10 medRxiv medRxiv NNS cord-354133-11b0d499 151 11 a a DT cord-354133-11b0d499 151 12 license license NN cord-354133-11b0d499 151 13 to to TO cord-354133-11b0d499 151 14 display display VB cord-354133-11b0d499 151 15 the the DT cord-354133-11b0d499 151 16 preprint preprint NN cord-354133-11b0d499 151 17 in in IN cord-354133-11b0d499 151 18 ( ( -LRB- cord-354133-11b0d499 151 19 which which WDT cord-354133-11b0d499 151 20 was be VBD cord-354133-11b0d499 151 21 not not RB cord-354133-11b0d499 151 22 certified certify VBN cord-354133-11b0d499 151 23 by by IN cord-354133-11b0d499 151 24 peer peer NN cord-354133-11b0d499 151 25 review review NN cord-354133-11b0d499 151 26 ) ) -RRB- cord-354133-11b0d499 151 27 preprint preprint NN cord-354133-11b0d499 152 1 The the DT cord-354133-11b0d499 152 2 copyright copyright NN cord-354133-11b0d499 152 3 holder holder NN cord-354133-11b0d499 152 4 for for IN cord-354133-11b0d499 152 5 this this DT cord-354133-11b0d499 152 6 this this DT cord-354133-11b0d499 152 7 version version NN cord-354133-11b0d499 152 8 posted post VBD cord-354133-11b0d499 152 9 October October NNP cord-354133-11b0d499 152 10 27 27 CD cord-354133-11b0d499 152 11 , , , cord-354133-11b0d499 152 12 2020 2020 CD cord-354133-11b0d499 152 13 . . . cord-354133-11b0d499 153 1 ; ; : cord-354133-11b0d499 153 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 153 3 doi doi NN cord-354133-11b0d499 153 4 : : : cord-354133-11b0d499 154 1 medRxiv medRxiv NNP cord-354133-11b0d499 154 2 preprint preprint NNP cord-354133-11b0d499 155 1 The the DT cord-354133-11b0d499 155 2 differences difference NNS cord-354133-11b0d499 155 3 in in IN cord-354133-11b0d499 155 4 delay delay NN cord-354133-11b0d499 155 5 times time NNS cord-354133-11b0d499 155 6 are be VBP cord-354133-11b0d499 155 7 also also RB cord-354133-11b0d499 155 8 startling startling JJ cord-354133-11b0d499 155 9 , , , cord-354133-11b0d499 155 10 ranging range VBG cord-354133-11b0d499 155 11 from from IN cord-354133-11b0d499 155 12 zero zero CD cord-354133-11b0d499 155 13 to to TO cord-354133-11b0d499 155 14 24 24 CD cord-354133-11b0d499 155 15 days day NNS cord-354133-11b0d499 155 16 with with IN cord-354133-11b0d499 155 17 no no DT cord-354133-11b0d499 155 18 clear clear JJ cord-354133-11b0d499 155 19 pattern pattern NN cord-354133-11b0d499 155 20 . . . cord-354133-11b0d499 156 1 This this DT cord-354133-11b0d499 156 2 delay delay NN cord-354133-11b0d499 156 3 between between IN cord-354133-11b0d499 156 4 reported report VBN cord-354133-11b0d499 156 5 cases case NNS cord-354133-11b0d499 156 6 and and CC cord-354133-11b0d499 156 7 deaths death NNS cord-354133-11b0d499 156 8 may may MD cord-354133-11b0d499 156 9 be be VB cord-354133-11b0d499 156 10 informative informative JJ cord-354133-11b0d499 156 11 regarding regard VBG cord-354133-11b0d499 156 12 the the DT cord-354133-11b0d499 156 13 state state NN cord-354133-11b0d499 156 14 of of IN cord-354133-11b0d499 156 15 reporting reporting NN cord-354133-11b0d499 156 16 or or CC cord-354133-11b0d499 156 17 testing testing NN cord-354133-11b0d499 156 18 in in IN cord-354133-11b0d499 156 19 a a DT cord-354133-11b0d499 156 20 country country NN cord-354133-11b0d499 157 1 but but CC cord-354133-11b0d499 157 2 it -PRON- PRP cord-354133-11b0d499 157 3 is be VBZ cord-354133-11b0d499 157 4 difficult difficult JJ cord-354133-11b0d499 157 5 to to TO cord-354133-11b0d499 157 6 interpret interpret VB cord-354133-11b0d499 157 7 . . . cord-354133-11b0d499 158 1 The the DT cord-354133-11b0d499 158 2 mean mean JJ cord-354133-11b0d499 158 3 delay delay NN cord-354133-11b0d499 158 4 between between IN cord-354133-11b0d499 158 5 onset onset NN cord-354133-11b0d499 158 6 of of IN cord-354133-11b0d499 158 7 symptoms symptom NNS cord-354133-11b0d499 158 8 and and CC cord-354133-11b0d499 158 9 death death NN cord-354133-11b0d499 158 10 has have VBZ cord-354133-11b0d499 158 11 been be VBN cord-354133-11b0d499 158 12 estimated estimate VBN cord-354133-11b0d499 158 13 at at IN cord-354133-11b0d499 158 14 12 12 CD cord-354133-11b0d499 158 15 - - SYM cord-354133-11b0d499 158 16 22 22 CD cord-354133-11b0d499 158 17 days day NNS cord-354133-11b0d499 158 18 using use VBG cord-354133-11b0d499 158 19 case case NN cord-354133-11b0d499 158 20 data datum NNS cord-354133-11b0d499 158 21 [ [ -LRB- cord-354133-11b0d499 158 22 2 2 CD cord-354133-11b0d499 158 23 , , , cord-354133-11b0d499 158 24 5 5 CD cord-354133-11b0d499 158 25 , , , cord-354133-11b0d499 158 26 7 7 CD cord-354133-11b0d499 158 27 , , , cord-354133-11b0d499 158 28 10 10 CD cord-354133-11b0d499 158 29 , , , cord-354133-11b0d499 158 30 12 12 CD cord-354133-11b0d499 158 31 , , , cord-354133-11b0d499 158 32 16 16 CD cord-354133-11b0d499 158 33 ] ] -RRB- cord-354133-11b0d499 158 34 , , , cord-354133-11b0d499 158 35 but but CC cord-354133-11b0d499 158 36 there there EX cord-354133-11b0d499 158 37 are be VBP cord-354133-11b0d499 158 38 also also RB cord-354133-11b0d499 158 39 delays delay NNS cord-354133-11b0d499 158 40 between between IN cord-354133-11b0d499 158 41 onset onset NN cord-354133-11b0d499 158 42 of of IN cord-354133-11b0d499 158 43 symptoms symptom NNS cord-354133-11b0d499 158 44 and and CC cord-354133-11b0d499 158 45 testing testing NN cord-354133-11b0d499 158 46 , , , cord-354133-11b0d499 158 47 between between IN cord-354133-11b0d499 158 48 testing testing NN cord-354133-11b0d499 158 49 and and CC cord-354133-11b0d499 158 50 reporting reporting NN cord-354133-11b0d499 158 51 of of IN cord-354133-11b0d499 158 52 results result NNS cord-354133-11b0d499 158 53 , , , cord-354133-11b0d499 158 54 and and CC cord-354133-11b0d499 158 55 in in IN cord-354133-11b0d499 158 56 reporting reporting NN cord-354133-11b0d499 158 57 of of IN cord-354133-11b0d499 158 58 deaths death NNS cord-354133-11b0d499 158 59 . . . cord-354133-11b0d499 159 1 For for IN cord-354133-11b0d499 159 2 example example NN cord-354133-11b0d499 159 3 , , , cord-354133-11b0d499 159 4 in in IN cord-354133-11b0d499 159 5 Sweden Sweden NNP cord-354133-11b0d499 159 6 a a DT cord-354133-11b0d499 159 7 mean mean JJ cord-354133-11b0d499 159 8 delay delay NN cord-354133-11b0d499 159 9 of of IN cord-354133-11b0d499 159 10 five five CD cord-354133-11b0d499 159 11 days day NNS cord-354133-11b0d499 159 12 between between IN cord-354133-11b0d499 159 13 onset onset NN cord-354133-11b0d499 159 14 of of IN cord-354133-11b0d499 159 15 symptoms symptom NNS cord-354133-11b0d499 159 16 and and CC cord-354133-11b0d499 159 17 the the DT cord-354133-11b0d499 159 18 " " `` cord-354133-11b0d499 159 19 statistical statistical JJ cord-354133-11b0d499 159 20 date date NN cord-354133-11b0d499 159 21 " " '' cord-354133-11b0d499 159 22 of of IN cord-354133-11b0d499 159 23 a a DT cord-354133-11b0d499 159 24 reported report VBN cord-354133-11b0d499 159 25 case case NN cord-354133-11b0d499 159 26 ( ( -LRB- cord-354133-11b0d499 159 27 including include VBG cord-354133-11b0d499 159 28 one one CD cord-354133-11b0d499 159 29 day day NN cord-354133-11b0d499 159 30 from from IN cord-354133-11b0d499 159 31 test test NN cord-354133-11b0d499 159 32 to to TO cord-354133-11b0d499 159 33 statistic statistic NN cord-354133-11b0d499 159 34 ) ) -RRB- cord-354133-11b0d499 159 35 was be VBD cord-354133-11b0d499 159 36 reported report VBN cord-354133-11b0d499 159 37 [ [ -LRB- cord-354133-11b0d499 159 38 7 7 CD cord-354133-11b0d499 159 39 ] ] -RRB- cord-354133-11b0d499 159 40 . . . cord-354133-11b0d499 160 1 In in IN cord-354133-11b0d499 160 2 some some DT cord-354133-11b0d499 160 3 countries country NNS cord-354133-11b0d499 160 4 , , , cord-354133-11b0d499 160 5 tests test NNS cord-354133-11b0d499 160 6 are be VBP cord-354133-11b0d499 160 7 only only RB cord-354133-11b0d499 160 8 administered administer VBN cord-354133-11b0d499 160 9 to to IN cord-354133-11b0d499 160 10 the the DT cord-354133-11b0d499 160 11 sickest sick JJS cord-354133-11b0d499 160 12 patients patient NNS cord-354133-11b0d499 160 13 ( ( -LRB- cord-354133-11b0d499 160 14 many many JJ cord-354133-11b0d499 160 15 days day NNS cord-354133-11b0d499 160 16 after after IN cord-354133-11b0d499 160 17 onset onset NN cord-354133-11b0d499 160 18 ) ) -RRB- cord-354133-11b0d499 160 19 , , , cord-354133-11b0d499 160 20 and and CC cord-354133-11b0d499 160 21 in in IN cord-354133-11b0d499 160 22 others other NNS cord-354133-11b0d499 160 23 , , , cord-354133-11b0d499 160 24 test test NN cord-354133-11b0d499 160 25 results result NNS cord-354133-11b0d499 160 26 can can MD cord-354133-11b0d499 160 27 take take VB cord-354133-11b0d499 160 28 up up RP cord-354133-11b0d499 160 29 to to IN cord-354133-11b0d499 160 30 a a DT cord-354133-11b0d499 160 31 few few JJ cord-354133-11b0d499 160 32 weeks week NNS cord-354133-11b0d499 160 33 . . . cord-354133-11b0d499 161 1 We -PRON- PRP cord-354133-11b0d499 161 2 note note VBP cord-354133-11b0d499 161 3 that that IN cord-354133-11b0d499 161 4 for for IN cord-354133-11b0d499 161 5 Australia Australia NNP cord-354133-11b0d499 161 6 and and CC cord-354133-11b0d499 161 7 New New NNP cord-354133-11b0d499 161 8 Zealand Zealand NNP cord-354133-11b0d499 161 9 , , , cord-354133-11b0d499 161 10 where where WRB cord-354133-11b0d499 161 11 case case NN cord-354133-11b0d499 161 12 numbers number NNS cord-354133-11b0d499 161 13 have have VBP cord-354133-11b0d499 161 14 been be VBN cord-354133-11b0d499 161 15 low low JJ cord-354133-11b0d499 161 16 and and CC cord-354133-11b0d499 161 17 testing test VBG cord-354133-11b0d499 161 18 extensive extensive JJ cord-354133-11b0d499 161 19 and and CC cord-354133-11b0d499 161 20 rapid rapid JJ cord-354133-11b0d499 161 21 , , , cord-354133-11b0d499 161 22 the the DT cord-354133-11b0d499 161 23 calculated calculate VBN cord-354133-11b0d499 161 24 time time NN cord-354133-11b0d499 161 25 delay delay NN cord-354133-11b0d499 161 26 is be VBZ cord-354133-11b0d499 161 27 more more JJR cord-354133-11b0d499 161 28 than than IN cord-354133-11b0d499 161 29 ten ten CD cord-354133-11b0d499 161 30 days day NNS cord-354133-11b0d499 161 31 , , , cord-354133-11b0d499 161 32 whereas whereas IN cord-354133-11b0d499 161 33 many many JJ cord-354133-11b0d499 161 34 of of IN cord-354133-11b0d499 161 35 the the DT cord-354133-11b0d499 161 36 harder hard RBR cord-354133-11b0d499 161 37 - - HYPH cord-354133-11b0d499 161 38 hit hit VBN cord-354133-11b0d499 161 39 countries country NNS cord-354133-11b0d499 161 40 in in IN cord-354133-11b0d499 161 41 western western JJ cord-354133-11b0d499 161 42 Europe Europe NNP cord-354133-11b0d499 161 43 and and CC cord-354133-11b0d499 161 44 North North NNP cord-354133-11b0d499 161 45 America America NNP cord-354133-11b0d499 161 46 have have VBP cord-354133-11b0d499 161 47 much much RB cord-354133-11b0d499 161 48 shorter short JJR cord-354133-11b0d499 161 49 calculated calculate VBN cord-354133-11b0d499 161 50 time time NN cord-354133-11b0d499 161 51 delays delay NNS cord-354133-11b0d499 161 52 . . . cord-354133-11b0d499 162 1 Spain Spain NNP cord-354133-11b0d499 162 2 is be VBZ cord-354133-11b0d499 162 3 an an DT cord-354133-11b0d499 162 4 interesting interesting JJ cord-354133-11b0d499 162 5 case case NN cord-354133-11b0d499 162 6 . . . cord-354133-11b0d499 163 1 Until until IN cord-354133-11b0d499 163 2 12 12 CD cord-354133-11b0d499 163 3 August August NNP cord-354133-11b0d499 163 4 , , , cord-354133-11b0d499 163 5 TSD TSD NNP cord-354133-11b0d499 163 6 analysis analysis NN cord-354133-11b0d499 163 7 using use VBG cord-354133-11b0d499 163 8 Spanish spanish JJ cord-354133-11b0d499 163 9 data datum NNS cord-354133-11b0d499 163 10 from from IN cord-354133-11b0d499 163 11 the the DT cord-354133-11b0d499 163 12 Worldometer Worldometer NNP cord-354133-11b0d499 163 13 website website NN cord-354133-11b0d499 163 14 [ [ -LRB- cord-354133-11b0d499 163 15 23 23 CD cord-354133-11b0d499 163 16 ] ] -RRB- cord-354133-11b0d499 163 17 gave give VBD cord-354133-11b0d499 163 18 a a DT cord-354133-11b0d499 163 19 stable stable JJ cord-354133-11b0d499 163 20 CFR CFR NNP cord-354133-11b0d499 163 21 of of IN cord-354133-11b0d499 163 22 10 10 CD cord-354133-11b0d499 163 23 % % NN cord-354133-11b0d499 163 24 with with IN cord-354133-11b0d499 163 25 a a DT cord-354133-11b0d499 163 26 delay delay NN cord-354133-11b0d499 163 27 time time NN cord-354133-11b0d499 163 28 of of IN cord-354133-11b0d499 163 29 one one CD cord-354133-11b0d499 163 30 day day NN cord-354133-11b0d499 163 31 . . . cord-354133-11b0d499 164 1 On on IN cord-354133-11b0d499 164 2 that that DT cord-354133-11b0d499 164 3 day day NN cord-354133-11b0d499 164 4 , , , cord-354133-11b0d499 164 5 data datum NNS cord-354133-11b0d499 164 6 were be VBD cord-354133-11b0d499 164 7 " " `` cord-354133-11b0d499 164 8 adjusted adjust VBN cord-354133-11b0d499 164 9 retrospectively retrospectively RB cord-354133-11b0d499 164 10 by by IN cord-354133-11b0d499 164 11 national national JJ cord-354133-11b0d499 164 12 authorities authority NNS cord-354133-11b0d499 164 13 : : : cord-354133-11b0d499 164 14 case case NN cord-354133-11b0d499 164 15 counts count VBZ cord-354133-11b0d499 164 16 adjusted adjust VBN cord-354133-11b0d499 164 17 from from IN cord-354133-11b0d499 164 18 2 2 CD cord-354133-11b0d499 164 19 February February NNP cord-354133-11b0d499 164 20 to to IN cord-354133-11b0d499 165 1 11 11 CD cord-354133-11b0d499 165 2 August August NNP cord-354133-11b0d499 165 3 and and CC cord-354133-11b0d499 165 4 death death NN cord-354133-11b0d499 165 5 counts count NNS cord-354133-11b0d499 165 6 adjusted adjust VBN cord-354133-11b0d499 165 7 from from IN cord-354133-11b0d499 165 8 26 26 CD cord-354133-11b0d499 165 9 April April NNP cord-354133-11b0d499 165 10 to to IN cord-354133-11b0d499 165 11 11 11 CD cord-354133-11b0d499 165 12 August August NNP cord-354133-11b0d499 165 13 " " '' cord-354133-11b0d499 165 14 according accord VBG cord-354133-11b0d499 165 15 to to IN cord-354133-11b0d499 165 16 the the DT cord-354133-11b0d499 165 17 World World NNP cord-354133-11b0d499 165 18 Health Health NNP cord-354133-11b0d499 165 19 Organisation Organisation NNP cord-354133-11b0d499 165 20 ( ( -LRB- cord-354133-11b0d499 165 21 WHO who WP cord-354133-11b0d499 165 22 ) ) -RRB- cord-354133-11b0d499 165 23 [ [ -LRB- cord-354133-11b0d499 165 24 24 24 CD cord-354133-11b0d499 165 25 ] ] -RRB- cord-354133-11b0d499 165 26 . . . cord-354133-11b0d499 166 1 Using use VBG cord-354133-11b0d499 166 2 the the DT cord-354133-11b0d499 166 3 revised revise VBN cord-354133-11b0d499 166 4 data datum NNS cord-354133-11b0d499 166 5 , , , cord-354133-11b0d499 166 6 the the DT cord-354133-11b0d499 166 7 TSD TSD NNP cord-354133-11b0d499 166 8 analysis analysis NN cord-354133-11b0d499 166 9 provided provide VBD cord-354133-11b0d499 166 10 an an DT cord-354133-11b0d499 166 11 even even RB cord-354133-11b0d499 166 12 more more RBR cord-354133-11b0d499 166 13 robust robust JJ cord-354133-11b0d499 166 14 fit fit NN cord-354133-11b0d499 166 15 ; ; : cord-354133-11b0d499 166 16 the the DT cord-354133-11b0d499 166 17 CFR CFR NNP cord-354133-11b0d499 166 18 was be VBD cord-354133-11b0d499 166 19 almost almost RB cord-354133-11b0d499 166 20 unchanged unchanged JJ cord-354133-11b0d499 166 21 at at IN cord-354133-11b0d499 166 22 11 11 CD cord-354133-11b0d499 166 23 % % NN cord-354133-11b0d499 166 24 but but CC cord-354133-11b0d499 166 25 the the DT cord-354133-11b0d499 166 26 delay delay NN cord-354133-11b0d499 166 27 time time NN cord-354133-11b0d499 166 28 was be VBD cord-354133-11b0d499 166 29 increased increase VBN cord-354133-11b0d499 166 30 to to IN cord-354133-11b0d499 166 31 14 14 CD cord-354133-11b0d499 166 32 days day NNS cord-354133-11b0d499 166 33 . . . cord-354133-11b0d499 167 1 This this DT cord-354133-11b0d499 167 2 means mean VBZ cord-354133-11b0d499 167 3 that that IN cord-354133-11b0d499 167 4 early early JJ cord-354133-11b0d499 167 5 data datum NNS cord-354133-11b0d499 167 6 from from IN cord-354133-11b0d499 167 7 Spain Spain NNP cord-354133-11b0d499 167 8 , , , cord-354133-11b0d499 167 9 which which WDT cord-354133-11b0d499 167 10 were be VBD cord-354133-11b0d499 167 11 erratic erratic JJ cord-354133-11b0d499 167 12 , , , cord-354133-11b0d499 167 13 reflected reflect VBD cord-354133-11b0d499 167 14 a a DT cord-354133-11b0d499 167 15 much much RB cord-354133-11b0d499 167 16 shorter short JJR cord-354133-11b0d499 167 17 delay delay NN cord-354133-11b0d499 167 18 between between IN cord-354133-11b0d499 167 19 reported report VBN cord-354133-11b0d499 167 20 cases case NNS cord-354133-11b0d499 167 21 and and CC cord-354133-11b0d499 167 22 deaths death NNS cord-354133-11b0d499 167 23 . . . cord-354133-11b0d499 168 1 In in IN cord-354133-11b0d499 168 2 fact fact NN cord-354133-11b0d499 168 3 , , , cord-354133-11b0d499 168 4 the the DT cord-354133-11b0d499 168 5 death death NN cord-354133-11b0d499 168 6 data datum NNS cord-354133-11b0d499 168 7 were be VBD cord-354133-11b0d499 168 8 largely largely RB cord-354133-11b0d499 168 9 unaffected unaffected JJ cord-354133-11b0d499 168 10 by by IN cord-354133-11b0d499 168 11 the the DT cord-354133-11b0d499 168 12 August August NNP cord-354133-11b0d499 168 13 revision revision NN cord-354133-11b0d499 168 14 , , , cord-354133-11b0d499 168 15 but but CC cord-354133-11b0d499 168 16 the the DT cord-354133-11b0d499 168 17 dates date NNS cord-354133-11b0d499 168 18 of of IN cord-354133-11b0d499 168 19 reported report VBN cord-354133-11b0d499 168 20 cases case NNS cord-354133-11b0d499 168 21 had have VBD cord-354133-11b0d499 168 22 shifted shift VBN cord-354133-11b0d499 168 23 nearly nearly RB cord-354133-11b0d499 168 24 two two CD cord-354133-11b0d499 168 25 weeks week NNS cord-354133-11b0d499 168 26 earlier early RBR cord-354133-11b0d499 168 27 , , , cord-354133-11b0d499 168 28 presumably presumably RB cord-354133-11b0d499 168 29 to to TO cord-354133-11b0d499 168 30 better better RB cord-354133-11b0d499 168 31 capture capture VB cord-354133-11b0d499 168 32 the the DT cord-354133-11b0d499 168 33 onset onset NN cord-354133-11b0d499 168 34 time time NN cord-354133-11b0d499 168 35 . . . cord-354133-11b0d499 169 1 This this DT cord-354133-11b0d499 169 2 shows show VBZ cord-354133-11b0d499 169 3 that that IN cord-354133-11b0d499 169 4 a a DT cord-354133-11b0d499 169 5 short short JJ cord-354133-11b0d499 169 6 delay delay NN cord-354133-11b0d499 169 7 time time NN cord-354133-11b0d499 169 8 can can MD cord-354133-11b0d499 169 9 reflect reflect VB cord-354133-11b0d499 169 10 late late JJ cord-354133-11b0d499 169 11 reporting reporting NN cord-354133-11b0d499 169 12 of of IN cord-354133-11b0d499 169 13 cases case NNS cord-354133-11b0d499 169 14 , , , cord-354133-11b0d499 169 15 due due JJ cord-354133-11b0d499 169 16 either either CC cord-354133-11b0d499 169 17 to to IN cord-354133-11b0d499 169 18 testing test VBG cord-354133-11b0d499 169 19 late late RB cord-354133-11b0d499 169 20 in in IN cord-354133-11b0d499 169 21 the the DT cord-354133-11b0d499 169 22 progress progress NN cord-354133-11b0d499 169 23 of of IN cord-354133-11b0d499 169 24 the the DT cord-354133-11b0d499 169 25 disease disease NN cord-354133-11b0d499 169 26 ( ( -LRB- cord-354133-11b0d499 169 27 well well RB cord-354133-11b0d499 169 28 after after IN cord-354133-11b0d499 169 29 onset onset NN cord-354133-11b0d499 169 30 ) ) -RRB- cord-354133-11b0d499 169 31 or or CC cord-354133-11b0d499 169 32 delays delay NNS cord-354133-11b0d499 169 33 in in IN cord-354133-11b0d499 169 34 providing provide VBG cord-354133-11b0d499 169 35 test test NN cord-354133-11b0d499 169 36 results result NNS cord-354133-11b0d499 169 37 ( ( -LRB- cord-354133-11b0d499 169 38 or or CC cord-354133-11b0d499 169 39 both both DT cord-354133-11b0d499 169 40 ) ) -RRB- cord-354133-11b0d499 169 41 . . . cord-354133-11b0d499 170 1 This this DT cord-354133-11b0d499 170 2 may may MD cord-354133-11b0d499 170 3 explain explain VB cord-354133-11b0d499 170 4 the the DT cord-354133-11b0d499 170 5 short short JJ cord-354133-11b0d499 170 6 delay delay NN cord-354133-11b0d499 170 7 times time NNS cord-354133-11b0d499 170 8 for for IN cord-354133-11b0d499 170 9 the the DT cord-354133-11b0d499 170 10 United United NNP cord-354133-11b0d499 170 11 Kingdom Kingdom NNP cord-354133-11b0d499 170 12 , , , cord-354133-11b0d499 170 13 Italy Italy NNP cord-354133-11b0d499 170 14 , , , cord-354133-11b0d499 170 15 the the DT cord-354133-11b0d499 170 16 Netherlands Netherlands NNP cord-354133-11b0d499 170 17 and and CC cord-354133-11b0d499 170 18 the the DT cord-354133-11b0d499 170 19 USA USA NNP cord-354133-11b0d499 170 20 , , , cord-354133-11b0d499 170 21 as as RB cord-354133-11b0d499 170 22 well well RB cord-354133-11b0d499 170 23 as as IN cord-354133-11b0d499 170 24 many many JJ cord-354133-11b0d499 170 25 other other JJ cord-354133-11b0d499 170 26 countries country NNS cord-354133-11b0d499 170 27 ( ( -LRB- cord-354133-11b0d499 170 28 for for IN cord-354133-11b0d499 170 29 example example NN cord-354133-11b0d499 170 30 , , , cord-354133-11b0d499 170 31 is be VBZ cord-354133-11b0d499 170 32 the the DT cord-354133-11b0d499 170 33 author author NN cord-354133-11b0d499 170 34 / / SYM cord-354133-11b0d499 170 35 funder funder NN cord-354133-11b0d499 170 36 , , , cord-354133-11b0d499 170 37 who who WP cord-354133-11b0d499 170 38 has have VBZ cord-354133-11b0d499 170 39 granted grant VBN cord-354133-11b0d499 170 40 medRxiv medRxiv NNS cord-354133-11b0d499 170 41 a a DT cord-354133-11b0d499 170 42 license license NN cord-354133-11b0d499 170 43 to to TO cord-354133-11b0d499 170 44 display display VB cord-354133-11b0d499 170 45 the the DT cord-354133-11b0d499 170 46 preprint preprint NN cord-354133-11b0d499 170 47 in in IN cord-354133-11b0d499 170 48 ( ( -LRB- cord-354133-11b0d499 170 49 which which WDT cord-354133-11b0d499 170 50 was be VBD cord-354133-11b0d499 170 51 not not RB cord-354133-11b0d499 170 52 certified certify VBN cord-354133-11b0d499 170 53 by by IN cord-354133-11b0d499 170 54 peer peer NN cord-354133-11b0d499 170 55 review review NN cord-354133-11b0d499 170 56 ) ) -RRB- cord-354133-11b0d499 171 1 preprint preprint NN cord-354133-11b0d499 172 1 An an DT cord-354133-11b0d499 172 2 important important JJ cord-354133-11b0d499 172 3 conclusion conclusion NN cord-354133-11b0d499 172 4 from from IN cord-354133-11b0d499 172 5 this this DT cord-354133-11b0d499 172 6 analysis analysis NN cord-354133-11b0d499 172 7 concerns concern VBZ cord-354133-11b0d499 172 8 the the DT cord-354133-11b0d499 172 9 perils peril NNS cord-354133-11b0d499 172 10 in in IN cord-354133-11b0d499 172 11 calculating calculate VBG cord-354133-11b0d499 172 12 the the DT cord-354133-11b0d499 172 13 CFR CFR NNP cord-354133-11b0d499 172 14 using use VBG cord-354133-11b0d499 172 15 established establish VBN cord-354133-11b0d499 172 16 time time NN cord-354133-11b0d499 172 17 distributions distribution NNS cord-354133-11b0d499 172 18 for for IN cord-354133-11b0d499 172 19 onset onset NN cord-354133-11b0d499 172 20 to to IN cord-354133-11b0d499 172 21 death death NN cord-354133-11b0d499 172 22 obtained obtain VBN cord-354133-11b0d499 172 23 from from IN cord-354133-11b0d499 172 24 case case NN cord-354133-11b0d499 172 25 studies study NNS cord-354133-11b0d499 172 26 , , , cord-354133-11b0d499 172 27 as as IN cord-354133-11b0d499 172 28 is be VBZ cord-354133-11b0d499 172 29 common common JJ cord-354133-11b0d499 172 30 . . . cord-354133-11b0d499 173 1 The the DT cord-354133-11b0d499 173 2 beauty beauty NN cord-354133-11b0d499 173 3 of of IN cord-354133-11b0d499 173 4 this this DT cord-354133-11b0d499 173 5 simple simple JJ cord-354133-11b0d499 173 6 method method NN cord-354133-11b0d499 173 7 is be VBZ cord-354133-11b0d499 173 8 its -PRON- PRP$ cord-354133-11b0d499 173 9 transparency transparency NN cord-354133-11b0d499 174 1 -nothing -nothing NN cord-354133-11b0d499 174 2 is be VBZ cord-354133-11b0d499 174 3 assumed assume VBN cord-354133-11b0d499 174 4 and and CC cord-354133-11b0d499 174 5 the the DT cord-354133-11b0d499 174 6 data datum NNS cord-354133-11b0d499 174 7 are be VBP cord-354133-11b0d499 174 8 enabled enable VBN cord-354133-11b0d499 174 9 to to TO cord-354133-11b0d499 174 10 speak speak VB cord-354133-11b0d499 174 11 for for IN cord-354133-11b0d499 174 12 themselves -PRON- PRP cord-354133-11b0d499 174 13 , , , cord-354133-11b0d499 174 14 and and CC cord-354133-11b0d499 174 15 can can MD cord-354133-11b0d499 174 16 therefore therefore RB cord-354133-11b0d499 174 17 give give VB cord-354133-11b0d499 174 18 us -PRON- PRP cord-354133-11b0d499 174 19 information information NN cord-354133-11b0d499 174 20 that that IN cord-354133-11b0d499 174 21 we -PRON- PRP cord-354133-11b0d499 174 22 might may MD cord-354133-11b0d499 174 23 not not RB cord-354133-11b0d499 174 24 expect expect VB cord-354133-11b0d499 174 25 , , , cord-354133-11b0d499 174 26 rather rather RB cord-354133-11b0d499 174 27 than than IN cord-354133-11b0d499 174 28 merely merely RB cord-354133-11b0d499 174 29 reflecting reflect VBG cord-354133-11b0d499 174 30 our -PRON- PRP$ cord-354133-11b0d499 174 31 assumptions assumption NNS cord-354133-11b0d499 174 32 . . . cord-354133-11b0d499 175 1 We -PRON- PRP cord-354133-11b0d499 175 2 are be VBP cord-354133-11b0d499 175 3 interested interested JJ cord-354133-11b0d499 175 4 not not RB cord-354133-11b0d499 175 5 only only RB cord-354133-11b0d499 175 6 in in IN cord-354133-11b0d499 175 7 the the DT cord-354133-11b0d499 175 8 versatility versatility NN cord-354133-11b0d499 175 9 and and CC cord-354133-11b0d499 175 10 simplicity simplicity NN cord-354133-11b0d499 175 11 of of IN cord-354133-11b0d499 175 12 this this DT cord-354133-11b0d499 175 13 method method NN cord-354133-11b0d499 175 14 , , , cord-354133-11b0d499 175 15 but but CC cord-354133-11b0d499 175 16 also also RB cord-354133-11b0d499 175 17 in in IN cord-354133-11b0d499 175 18 what what WDT cord-354133-11b0d499 175 19 conclusions conclusion NNS cord-354133-11b0d499 175 20 may may MD cord-354133-11b0d499 175 21 be be VB cord-354133-11b0d499 175 22 drawn draw VBN cord-354133-11b0d499 175 23 from from IN cord-354133-11b0d499 175 24 the the DT cord-354133-11b0d499 175 25 parameters parameter NNS cord-354133-11b0d499 175 26 calculated calculate VBN cord-354133-11b0d499 175 27 -namely -namely RB cord-354133-11b0d499 175 28 , , , cord-354133-11b0d499 175 29 the the DT cord-354133-11b0d499 175 30 CFR CFR NNP cord-354133-11b0d499 175 31 and and CC cord-354133-11b0d499 175 32 the the DT cord-354133-11b0d499 175 33 delay delay NN cord-354133-11b0d499 175 34 time time NN cord-354133-11b0d499 175 35 . . . cord-354133-11b0d499 176 1 Reported report VBN cord-354133-11b0d499 176 2 CFR CFR NNP cord-354133-11b0d499 176 3 values value NNS cord-354133-11b0d499 176 4 for for IN cord-354133-11b0d499 176 5 COVID-19 covid-19 CD cord-354133-11b0d499 176 6 vary vary VBP cord-354133-11b0d499 176 7 widely widely RB cord-354133-11b0d499 176 8 , , , cord-354133-11b0d499 176 9 but but CC cord-354133-11b0d499 176 10 the the DT cord-354133-11b0d499 176 11 best good JJS cord-354133-11b0d499 176 12 current current JJ cord-354133-11b0d499 176 13 estimates estimate NNS cord-354133-11b0d499 176 14 of of IN cord-354133-11b0d499 176 15 the the DT cord-354133-11b0d499 176 16 true true JJ cord-354133-11b0d499 176 17 infection infection NN cord-354133-11b0d499 176 18 fatality fatality NN cord-354133-11b0d499 176 19 ratio ratio NN cord-354133-11b0d499 176 20 or or CC cord-354133-11b0d499 176 21 IFR IFR NNP cord-354133-11b0d499 176 22 ( ( -LRB- cord-354133-11b0d499 176 23 taking take VBG cord-354133-11b0d499 176 24 into into IN cord-354133-11b0d499 176 25 account account NN cord-354133-11b0d499 176 26 all all DT cord-354133-11b0d499 176 27 infections infection NNS cord-354133-11b0d499 176 28 including include VBG cord-354133-11b0d499 176 29 undiagnosed undiagnosed JJ cord-354133-11b0d499 176 30 and and CC cord-354133-11b0d499 176 31 asymptomatic asymptomatic JJ cord-354133-11b0d499 176 32 ) ) -RRB- cord-354133-11b0d499 176 33 are be VBP cord-354133-11b0d499 176 34 around around RB cord-354133-11b0d499 176 35 0.6 0.6 CD cord-354133-11b0d499 176 36 - - SYM cord-354133-11b0d499 176 37 0.7 0.7 CD cord-354133-11b0d499 176 38 % % NN cord-354133-11b0d499 176 39 [ [ -LRB- cord-354133-11b0d499 176 40 4 4 CD cord-354133-11b0d499 176 41 , , , cord-354133-11b0d499 176 42 6 6 CD cord-354133-11b0d499 176 43 ] ] -RRB- cord-354133-11b0d499 176 44 based base VBN cord-354133-11b0d499 176 45 on on IN cord-354133-11b0d499 176 46 cruise cruise NN cord-354133-11b0d499 176 47 ship ship NN cord-354133-11b0d499 176 48 and and CC cord-354133-11b0d499 176 49 population population NN cord-354133-11b0d499 176 50 serology serology NN cord-354133-11b0d499 176 51 data datum NNS cord-354133-11b0d499 176 52 . . . cord-354133-11b0d499 177 1 The the DT cord-354133-11b0d499 177 2 very very RB cord-354133-11b0d499 177 3 high high JJ cord-354133-11b0d499 177 4 CFR CFR NNP cord-354133-11b0d499 177 5 values value NNS cord-354133-11b0d499 177 6 calculated calculate VBN cord-354133-11b0d499 177 7 for for IN cord-354133-11b0d499 177 8 many many JJ cord-354133-11b0d499 177 9 European european JJ cord-354133-11b0d499 177 10 countries country NNS cord-354133-11b0d499 177 11 in in IN cord-354133-11b0d499 177 12 particular particular JJ cord-354133-11b0d499 177 13 are be VBP cord-354133-11b0d499 177 14 probably probably RB cord-354133-11b0d499 177 15 vastly vastly RB cord-354133-11b0d499 177 16 inflated inflated JJ cord-354133-11b0d499 177 17 due due IN cord-354133-11b0d499 177 18 to to IN cord-354133-11b0d499 177 19 the the DT cord-354133-11b0d499 177 20 inadequate inadequate JJ cord-354133-11b0d499 177 21 testing testing NN cord-354133-11b0d499 177 22 and and CC cord-354133-11b0d499 177 23 overwhelmed overwhelmed JJ cord-354133-11b0d499 177 24 health health NN cord-354133-11b0d499 177 25 systems system NNS cord-354133-11b0d499 177 26 in in IN cord-354133-11b0d499 177 27 these these DT cord-354133-11b0d499 177 28 countries country NNS cord-354133-11b0d499 177 29 , , , cord-354133-11b0d499 177 30 which which WDT cord-354133-11b0d499 177 31 result result VBP cord-354133-11b0d499 177 32 in in IN cord-354133-11b0d499 177 33 underestimation underestimation NN cord-354133-11b0d499 177 34 of of IN cord-354133-11b0d499 177 35 case case NN cord-354133-11b0d499 177 36 numbers number NNS cord-354133-11b0d499 177 37 . . . cord-354133-11b0d499 178 1 However however RB cord-354133-11b0d499 178 2 , , , cord-354133-11b0d499 178 3 it -PRON- PRP cord-354133-11b0d499 178 4 is be VBZ cord-354133-11b0d499 178 5 an an DT cord-354133-11b0d499 178 6 oversimplification oversimplification NN cord-354133-11b0d499 178 7 to to TO cord-354133-11b0d499 178 8 assume assume VB cord-354133-11b0d499 178 9 that that IN cord-354133-11b0d499 178 10 this this DT cord-354133-11b0d499 178 11 is be VBZ cord-354133-11b0d499 178 12 the the DT cord-354133-11b0d499 178 13 only only JJ cord-354133-11b0d499 178 14 relevant relevant JJ cord-354133-11b0d499 178 15 factor factor NN cord-354133-11b0d499 178 16 that that WDT cord-354133-11b0d499 178 17 differs differ VBZ cord-354133-11b0d499 178 18 between between IN cord-354133-11b0d499 178 19 countries country NNS cord-354133-11b0d499 178 20 , , , cord-354133-11b0d499 178 21 since since IN cord-354133-11b0d499 178 22 we -PRON- PRP cord-354133-11b0d499 178 23 know know VBP cord-354133-11b0d499 178 24 that that IN cord-354133-11b0d499 178 25 demographics demographic NNS cord-354133-11b0d499 178 26 and and CC cord-354133-11b0d499 178 27 health health NN cord-354133-11b0d499 178 28 systems system NNS cord-354133-11b0d499 178 29 ( ( -LRB- cord-354133-11b0d499 178 30 among among IN cord-354133-11b0d499 178 31 other other JJ cord-354133-11b0d499 178 32 things thing NNS cord-354133-11b0d499 178 33 ) ) -RRB- cord-354133-11b0d499 178 34 can can MD cord-354133-11b0d499 178 35 also also RB cord-354133-11b0d499 178 36 affect affect VB cord-354133-11b0d499 178 37 survival survival NN cord-354133-11b0d499 178 38 probability probability NN cord-354133-11b0d499 178 39 . . . cord-354133-11b0d499 179 1 Such such PDT cord-354133-11b0d499 179 2 an an DT cord-354133-11b0d499 179 3 assumption assumption NN cord-354133-11b0d499 179 4 has have VBZ cord-354133-11b0d499 179 5 been be VBN cord-354133-11b0d499 179 6 used use VBN cord-354133-11b0d499 179 7 in in IN cord-354133-11b0d499 179 8 various various JJ cord-354133-11b0d499 179 9 studies study NNS cord-354133-11b0d499 179 10 , , , cord-354133-11b0d499 179 11 in in IN cord-354133-11b0d499 179 12 order order NN cord-354133-11b0d499 179 13 to to TO cord-354133-11b0d499 179 14 compare compare VB cord-354133-11b0d499 179 15 the the DT cord-354133-11b0d499 179 16 effectiveness effectiveness NN cord-354133-11b0d499 179 17 of of IN cord-354133-11b0d499 179 18 different different JJ cord-354133-11b0d499 179 19 countries country NNS cord-354133-11b0d499 179 20 ' ' POS cord-354133-11b0d499 179 21 reporting reporting NN cord-354133-11b0d499 179 22 systems system NNS cord-354133-11b0d499 179 23 and and CC cord-354133-11b0d499 179 24 to to TO cord-354133-11b0d499 179 25 correct correct VB cord-354133-11b0d499 179 26 case case NN cord-354133-11b0d499 179 27 numbers number NNS cord-354133-11b0d499 179 28 [ [ -LRB- cord-354133-11b0d499 179 29 4 4 CD cord-354133-11b0d499 179 30 , , , cord-354133-11b0d499 179 31 25 25 CD cord-354133-11b0d499 179 32 ] ] -RRB- cord-354133-11b0d499 179 33 . . . cord-354133-11b0d499 180 1 However however RB cord-354133-11b0d499 180 2 , , , cord-354133-11b0d499 180 3 by by IN cord-354133-11b0d499 180 4 assuming assume VBG cord-354133-11b0d499 180 5 that that IN cord-354133-11b0d499 180 6 the the DT cord-354133-11b0d499 180 7 IFR IFR NNP cord-354133-11b0d499 180 8 is be VBZ cord-354133-11b0d499 180 9 identical identical JJ cord-354133-11b0d499 180 10 everywhere everywhere RB cord-354133-11b0d499 180 11 at at IN cord-354133-11b0d499 180 12 all all DT cord-354133-11b0d499 180 13 times time NNS cord-354133-11b0d499 180 14 , , , cord-354133-11b0d499 180 15 valuable valuable JJ cord-354133-11b0d499 180 16 information information NN cord-354133-11b0d499 180 17 is be VBZ cord-354133-11b0d499 180 18 lost lose VBN cord-354133-11b0d499 180 19 and and CC cord-354133-11b0d499 180 20 conclusions conclusion NNS cord-354133-11b0d499 180 21 may may MD cord-354133-11b0d499 180 22 be be VB cord-354133-11b0d499 180 23 misleading misleading JJ cord-354133-11b0d499 180 24 . . . cord-354133-11b0d499 181 1 is be VBZ cord-354133-11b0d499 181 2 the the DT cord-354133-11b0d499 181 3 author author NN cord-354133-11b0d499 181 4 / / SYM cord-354133-11b0d499 181 5 funder funder NN cord-354133-11b0d499 181 6 , , , cord-354133-11b0d499 181 7 who who WP cord-354133-11b0d499 181 8 has have VBZ cord-354133-11b0d499 181 9 granted grant VBN cord-354133-11b0d499 181 10 medRxiv medRxiv NNS cord-354133-11b0d499 181 11 a a DT cord-354133-11b0d499 181 12 license license NN cord-354133-11b0d499 181 13 to to TO cord-354133-11b0d499 181 14 display display VB cord-354133-11b0d499 181 15 the the DT cord-354133-11b0d499 181 16 preprint preprint NN cord-354133-11b0d499 181 17 in in IN cord-354133-11b0d499 181 18 ( ( -LRB- cord-354133-11b0d499 181 19 which which WDT cord-354133-11b0d499 181 20 was be VBD cord-354133-11b0d499 181 21 not not RB cord-354133-11b0d499 181 22 certified certify VBN cord-354133-11b0d499 181 23 by by IN cord-354133-11b0d499 181 24 peer peer NN cord-354133-11b0d499 181 25 review review NN cord-354133-11b0d499 181 26 ) ) -RRB- cord-354133-11b0d499 181 27 preprint preprint NN cord-354133-11b0d499 182 1 The the DT cord-354133-11b0d499 182 2 copyright copyright NN cord-354133-11b0d499 182 3 holder holder NN cord-354133-11b0d499 182 4 for for IN cord-354133-11b0d499 182 5 this this DT cord-354133-11b0d499 182 6 this this DT cord-354133-11b0d499 182 7 version version NN cord-354133-11b0d499 182 8 posted post VBD cord-354133-11b0d499 182 9 October October NNP cord-354133-11b0d499 182 10 27 27 CD cord-354133-11b0d499 182 11 , , , cord-354133-11b0d499 182 12 2020 2020 CD cord-354133-11b0d499 182 13 . . . cord-354133-11b0d499 183 1 ; ; : cord-354133-11b0d499 183 2 https://doi.org/10.1101/2020 https://doi.org/10.1101/2020 NN cord-354133-11b0d499 183 3 . . . cord-354133-11b0d499 184 1 10.25.20216671 10.25.20216671 CD cord-354133-11b0d499 184 2 doi doi NN cord-354133-11b0d499 184 3 : : : cord-354133-11b0d499 185 1 medRxiv medRxiv NNP cord-354133-11b0d499 185 2 preprint preprint NNP cord-354133-11b0d499 186 1 In in IN cord-354133-11b0d499 186 2 this this DT cord-354133-11b0d499 186 3 study study NN cord-354133-11b0d499 186 4 , , , cord-354133-11b0d499 186 5 we -PRON- PRP cord-354133-11b0d499 186 6 estimate estimate VBP cord-354133-11b0d499 186 7 the the DT cord-354133-11b0d499 186 8 IFR IFR NNP cord-354133-11b0d499 186 9 from from IN cord-354133-11b0d499 186 10 the the DT cord-354133-11b0d499 186 11 CFR CFR NNP cord-354133-11b0d499 186 12 for for IN cord-354133-11b0d499 186 13 a a DT cord-354133-11b0d499 186 14 subset subset NN cord-354133-11b0d499 186 15 of of IN cord-354133-11b0d499 186 16 countries country NNS cord-354133-11b0d499 186 17 using use VBG cord-354133-11b0d499 186 18 seroprevalence seroprevalence NN cord-354133-11b0d499 186 19 data datum NNS cord-354133-11b0d499 186 20 ( ( -LRB- cord-354133-11b0d499 186 21 to to TO cord-354133-11b0d499 186 22 correct correct VB cord-354133-11b0d499 186 23 case case NN cord-354133-11b0d499 186 24 numbers number NNS cord-354133-11b0d499 186 25 ) ) -RRB- cord-354133-11b0d499 186 26 and and CC cord-354133-11b0d499 186 27 excess excess JJ cord-354133-11b0d499 186 28 death death NN cord-354133-11b0d499 186 29 data datum NNS cord-354133-11b0d499 186 30 ( ( -LRB- cord-354133-11b0d499 186 31 to to TO cord-354133-11b0d499 186 32 correct correct VB cord-354133-11b0d499 186 33 death death NN cord-354133-11b0d499 186 34 numbers number NNS cord-354133-11b0d499 186 35 ) ) -RRB- cord-354133-11b0d499 186 36 . . . cord-354133-11b0d499 187 1 Along along IN cord-354133-11b0d499 187 2 similar similar JJ cord-354133-11b0d499 187 3 lines line NNS cord-354133-11b0d499 187 4 , , , cord-354133-11b0d499 187 5 Ioannidis Ioannidis NNP cord-354133-11b0d499 187 6 [ [ -LRB- cord-354133-11b0d499 187 7 26 26 CD cord-354133-11b0d499 187 8 ] ] -RRB- cord-354133-11b0d499 187 9 previously previously RB cord-354133-11b0d499 187 10 estimated estimate VBD cord-354133-11b0d499 187 11 the the DT cord-354133-11b0d499 187 12 IFR IFR NNP cord-354133-11b0d499 187 13 for for IN cord-354133-11b0d499 187 14 various various JJ cord-354133-11b0d499 187 15 countries country NNS cord-354133-11b0d499 187 16 using use VBG cord-354133-11b0d499 187 17 seroprevalence seroprevalence NN cord-354133-11b0d499 187 18 data datum NNS cord-354133-11b0d499 187 19 and and CC cord-354133-11b0d499 187 20 cumulative cumulative JJ cord-354133-11b0d499 187 21 reported report VBN cord-354133-11b0d499 187 22 deaths death NNS cord-354133-11b0d499 187 23 at at IN cord-354133-11b0d499 187 24 a a DT cord-354133-11b0d499 187 25 corresponding corresponding JJ cord-354133-11b0d499 187 26 date date NN cord-354133-11b0d499 187 27 , , , cord-354133-11b0d499 187 28 although although IN cord-354133-11b0d499 187 29 this this DT cord-354133-11b0d499 187 30 does do VBZ cord-354133-11b0d499 187 31 not not RB cord-354133-11b0d499 187 32 account account VB cord-354133-11b0d499 187 33 for for IN cord-354133-11b0d499 187 34 either either CC cord-354133-11b0d499 187 35 excess excess JJ cord-354133-11b0d499 187 36 deaths death NNS cord-354133-11b0d499 187 37 or or CC cord-354133-11b0d499 187 38 the the DT cord-354133-11b0d499 187 39 relationship relationship NN cord-354133-11b0d499 187 40 between between IN cord-354133-11b0d499 187 41 cases case NNS cord-354133-11b0d499 187 42 and and CC cord-354133-11b0d499 187 43 deaths death NNS cord-354133-11b0d499 187 44 over over IN cord-354133-11b0d499 187 45 time time NN cord-354133-11b0d499 187 46 ; ; : cord-354133-11b0d499 187 47 in in IN cord-354133-11b0d499 187 48 fact fact NN cord-354133-11b0d499 187 49 , , , cord-354133-11b0d499 187 50 using use VBG cord-354133-11b0d499 187 51 seroprevalence seroprevalence NN cord-354133-11b0d499 187 52 and and CC cord-354133-11b0d499 187 53 death death NN cord-354133-11b0d499 187 54 data datum NNS cord-354133-11b0d499 187 55 alone alone RB cord-354133-11b0d499 187 56 reintroduces reintroduce VBZ cord-354133-11b0d499 187 57 the the DT cord-354133-11b0d499 187 58 issue issue NN cord-354133-11b0d499 187 59 of of IN cord-354133-11b0d499 187 60 the the DT cord-354133-11b0d499 187 61 unknown unknown JJ cord-354133-11b0d499 187 62 time time NN cord-354133-11b0d499 187 63 delay delay NN cord-354133-11b0d499 187 64 between between IN cord-354133-11b0d499 187 65 cases case NNS cord-354133-11b0d499 187 66 and and CC cord-354133-11b0d499 187 67 deaths death NNS cord-354133-11b0d499 187 68 , , , cord-354133-11b0d499 187 69 which which WDT cord-354133-11b0d499 187 70 must must MD cord-354133-11b0d499 187 71 be be VB cord-354133-11b0d499 187 72 approximated approximate VBN cord-354133-11b0d499 187 73 . . . cord-354133-11b0d499 188 1 We -PRON- PRP cord-354133-11b0d499 188 2 note note VBP cord-354133-11b0d499 188 3 that that IN cord-354133-11b0d499 188 4 studies study NNS cord-354133-11b0d499 188 5 from from IN cord-354133-11b0d499 188 6 very very RB cord-354133-11b0d499 188 7 early early RB cord-354133-11b0d499 188 8 in in IN cord-354133-11b0d499 188 9 the the DT cord-354133-11b0d499 188 10 pandemic pandemic NN cord-354133-11b0d499 188 11 provided provide VBD cord-354133-11b0d499 188 12 initial initial JJ cord-354133-11b0d499 188 13 estimates estimate NNS cord-354133-11b0d499 188 14 for for IN cord-354133-11b0d499 188 15 the the DT cord-354133-11b0d499 188 16 true true JJ cord-354133-11b0d499 188 17 prevalence prevalence NN cord-354133-11b0d499 188 18 of of IN cord-354133-11b0d499 188 19 COVID-19 covid-19 NN cord-354133-11b0d499 188 20 in in IN cord-354133-11b0d499 188 21 specific specific JJ cord-354133-11b0d499 188 22 places place NNS cord-354133-11b0d499 188 23 ; ; : cord-354133-11b0d499 188 24 a a DT cord-354133-11b0d499 188 25 spatiotemporal spatiotemporal JJ cord-354133-11b0d499 188 26 transmission transmission NN cord-354133-11b0d499 188 27 model model NN cord-354133-11b0d499 188 28 applied apply VBN cord-354133-11b0d499 188 29 to to IN cord-354133-11b0d499 188 30 Wuhan Wuhan NNP cord-354133-11b0d499 188 31 [ [ -LRB- cord-354133-11b0d499 188 32 27 27 CD cord-354133-11b0d499 188 33 ] ] -RRB- cord-354133-11b0d499 188 34 gave give VBD cord-354133-11b0d499 188 35 a a DT cord-354133-11b0d499 188 36 prevalence prevalence NN cord-354133-11b0d499 188 37 factor factor NN cord-354133-11b0d499 188 38 of of IN cord-354133-11b0d499 188 39 seven seven CD cord-354133-11b0d499 188 40 in in IN cord-354133-11b0d499 188 41 January January NNP cord-354133-11b0d499 188 42 ( ( -LRB- cord-354133-11b0d499 188 43 published publish VBN cord-354133-11b0d499 188 44 mid mid NNP cord-354133-11b0d499 188 45 - - NNP cord-354133-11b0d499 188 46 March March NNP cord-354133-11b0d499 188 47 ) ) -RRB- cord-354133-11b0d499 188 48 , , , cord-354133-11b0d499 188 49 and and CC cord-354133-11b0d499 188 50 a a DT cord-354133-11b0d499 188 51 statistical statistical JJ cord-354133-11b0d499 188 52 analysis analysis NN cord-354133-11b0d499 188 53 study study NN cord-354133-11b0d499 188 54 of of IN cord-354133-11b0d499 188 55 testing test VBG cord-354133-11b0d499 188 56 data datum NNS cord-354133-11b0d499 188 57 in in IN cord-354133-11b0d499 188 58 the the DT cord-354133-11b0d499 188 59 USA USA NNP cord-354133-11b0d499 188 60 [ [ -LRB- cord-354133-11b0d499 188 61 28 28 CD cord-354133-11b0d499 188 62 ] ] -RRB- cord-354133-11b0d499 188 63 estimated estimate VBD cord-354133-11b0d499 188 64 a a DT cord-354133-11b0d499 188 65 prevalence prevalence NN cord-354133-11b0d499 188 66 factor factor NN cord-354133-11b0d499 188 67 of of IN cord-354133-11b0d499 188 68 nine nine CD cord-354133-11b0d499 188 69 in in IN cord-354133-11b0d499 188 70 April April NNP cord-354133-11b0d499 188 71 ( ( -LRB- cord-354133-11b0d499 188 72 published publish VBN cord-354133-11b0d499 188 73 in in IN cord-354133-11b0d499 188 74 May May NNP cord-354133-11b0d499 188 75 ) ) -RRB- cord-354133-11b0d499 188 76 . . . cord-354133-11b0d499 189 1 These these DT cord-354133-11b0d499 189 2 early early JJ cord-354133-11b0d499 189 3 prevalence prevalence NN cord-354133-11b0d499 189 4 studies study NNS cord-354133-11b0d499 189 5 can can MD cord-354133-11b0d499 189 6 be be VB cord-354133-11b0d499 189 7 useful useful JJ cord-354133-11b0d499 189 8 in in IN cord-354133-11b0d499 189 9 roughly roughly RB cord-354133-11b0d499 189 10 correcting correct VBG cord-354133-11b0d499 189 11 the the DT cord-354133-11b0d499 189 12 CFR CFR NNP cord-354133-11b0d499 189 13 to to TO cord-354133-11b0d499 189 14 estimate estimate VB cord-354133-11b0d499 189 15 the the DT cord-354133-11b0d499 189 16 IFR IFR NNP cord-354133-11b0d499 189 17 before before IN cord-354133-11b0d499 189 18 rigorous rigorous JJ cord-354133-11b0d499 189 19 seroprevalence seroprevalence NN cord-354133-11b0d499 189 20 data datum NNS cord-354133-11b0d499 189 21 are be VBP cord-354133-11b0d499 189 22 available available JJ cord-354133-11b0d499 189 23 . . . cord-354133-11b0d499 190 1 In in IN cord-354133-11b0d499 190 2 Australia Australia NNP cord-354133-11b0d499 190 3 , , , cord-354133-11b0d499 190 4 case case NN cord-354133-11b0d499 190 5 numbers number NNS cord-354133-11b0d499 190 6 have have VBP cord-354133-11b0d499 190 7 been be VBN cord-354133-11b0d499 190 8 generally generally RB cord-354133-11b0d499 190 9 low low JJ cord-354133-11b0d499 190 10 ( ( -LRB- cord-354133-11b0d499 190 11 especially especially RB cord-354133-11b0d499 190 12 before before IN cord-354133-11b0d499 190 13 June June NNP cord-354133-11b0d499 190 14 ) ) -RRB- cord-354133-11b0d499 190 15 and and CC cord-354133-11b0d499 190 16 testing testing NN cord-354133-11b0d499 190 17 rates rate NNS cord-354133-11b0d499 190 18 high high JJ cord-354133-11b0d499 190 19 . . . cord-354133-11b0d499 191 1 It -PRON- PRP cord-354133-11b0d499 191 2 is be VBZ cord-354133-11b0d499 191 3 unlikely unlikely JJ cord-354133-11b0d499 191 4 that that IN cord-354133-11b0d499 191 5 there there EX cord-354133-11b0d499 191 6 have have VBP cord-354133-11b0d499 191 7 been be VBN cord-354133-11b0d499 191 8 appreciable appreciable JJ cord-354133-11b0d499 191 9 unreported unreported JJ cord-354133-11b0d499 191 10 COVID covid NN cord-354133-11b0d499 191 11 - - HYPH cord-354133-11b0d499 191 12 related relate VBN cord-354133-11b0d499 191 13 deaths death NNS cord-354133-11b0d499 191 14 [ [ -LRB- cord-354133-11b0d499 191 15 29 29 CD cord-354133-11b0d499 191 16 ] ] -RRB- cord-354133-11b0d499 191 17 . . . cord-354133-11b0d499 192 1 However however RB cord-354133-11b0d499 192 2 , , , cord-354133-11b0d499 192 3 even even RB cord-354133-11b0d499 192 4 with with IN cord-354133-11b0d499 192 5 robust robust JJ cord-354133-11b0d499 192 6 testing test VBG cord-354133-11b0d499 192 7 many many JJ cord-354133-11b0d499 192 8 cases case NNS cord-354133-11b0d499 192 9 will will MD cord-354133-11b0d499 192 10 be be VB cord-354133-11b0d499 192 11 undiagnosed undiagnosed JJ cord-354133-11b0d499 192 12 , , , cord-354133-11b0d499 192 13 especially especially RB cord-354133-11b0d499 192 14 asymptomatic asymptomatic JJ cord-354133-11b0d499 192 15 cases case NNS cord-354133-11b0d499 192 16 , , , cord-354133-11b0d499 192 17 which which WDT cord-354133-11b0d499 192 18 could could MD cord-354133-11b0d499 192 19 constitute constitute VB cord-354133-11b0d499 192 20 half half NN cord-354133-11b0d499 192 21 of of IN cord-354133-11b0d499 192 22 all all DT cord-354133-11b0d499 192 23 infections infection NNS cord-354133-11b0d499 192 24 [ [ -LRB- cord-354133-11b0d499 192 25 30 30 CD cord-354133-11b0d499 192 26 ] ] -RRB- cord-354133-11b0d499 192 27 . . . cord-354133-11b0d499 193 1 A a DT cord-354133-11b0d499 193 2 recent recent JJ cord-354133-11b0d499 193 3 seroprevalence seroprevalence NN cord-354133-11b0d499 193 4 study study NN cord-354133-11b0d499 193 5 of of IN cord-354133-11b0d499 193 6 elective elective JJ cord-354133-11b0d499 193 7 surgery surgery NN cord-354133-11b0d499 193 8 patients patient NNS cord-354133-11b0d499 193 9 in in IN cord-354133-11b0d499 193 10 four four CD cord-354133-11b0d499 193 11 states state NNS cord-354133-11b0d499 193 12 [ [ -LRB- cord-354133-11b0d499 193 13 31 31 CD cord-354133-11b0d499 193 14 ] ] -RRB- cord-354133-11b0d499 193 15 estimated estimate VBD cord-354133-11b0d499 193 16 that that IN cord-354133-11b0d499 193 17 the the DT cord-354133-11b0d499 193 18 number number NN cord-354133-11b0d499 193 19 of of IN cord-354133-11b0d499 193 20 true true JJ cord-354133-11b0d499 193 21 infections infection NNS cord-354133-11b0d499 193 22 was be VBD cord-354133-11b0d499 193 23 around around RB cord-354133-11b0d499 193 24 5 5 CD cord-354133-11b0d499 193 25 - - SYM cord-354133-11b0d499 193 26 10 10 CD cord-354133-11b0d499 193 27 times time NNS cord-354133-11b0d499 193 28 the the DT cord-354133-11b0d499 193 29 number number NN cord-354133-11b0d499 193 30 of of IN cord-354133-11b0d499 193 31 reported report VBN cord-354133-11b0d499 193 32 cases case NNS cord-354133-11b0d499 193 33 , , , cord-354133-11b0d499 193 34 although although IN cord-354133-11b0d499 193 35 the the DT cord-354133-11b0d499 193 36 authors author NNS cord-354133-11b0d499 193 37 state state VBP cord-354133-11b0d499 193 38 that that IN cord-354133-11b0d499 193 39 the the DT cord-354133-11b0d499 193 40 study study NN cord-354133-11b0d499 193 41 cohort cohort NN cord-354133-11b0d499 193 42 may may MD cord-354133-11b0d499 193 43 not not RB cord-354133-11b0d499 193 44 reflect reflect VB cord-354133-11b0d499 193 45 the the DT cord-354133-11b0d499 193 46 general general JJ cord-354133-11b0d499 193 47 population population NN cord-354133-11b0d499 193 48 ( ( -LRB- cord-354133-11b0d499 193 49 older old JJR cord-354133-11b0d499 193 50 individuals individual NNS cord-354133-11b0d499 193 51 overrepresented overrepresente VBN cord-354133-11b0d499 193 52 ) ) -RRB- cord-354133-11b0d499 193 53 . . . cord-354133-11b0d499 194 1 This this DT cord-354133-11b0d499 194 2 prevalence prevalence NN cord-354133-11b0d499 194 3 ratio ratio NN cord-354133-11b0d499 194 4 gives give VBZ cord-354133-11b0d499 194 5 an an DT cord-354133-11b0d499 194 6 approximate approximate JJ cord-354133-11b0d499 194 7 IFR IFR NNP cord-354133-11b0d499 194 8 for for IN cord-354133-11b0d499 194 9 Australia Australia NNP cord-354133-11b0d499 194 10 of of IN cord-354133-11b0d499 194 11 0.1 0.1 CD cord-354133-11b0d499 194 12 - - HYPH cord-354133-11b0d499 194 13 0.3 0.3 CD cord-354133-11b0d499 194 14 % % NN cord-354133-11b0d499 194 15 . . . cord-354133-11b0d499 195 1 Note note VB cord-354133-11b0d499 195 2 that that IN cord-354133-11b0d499 195 3 before before IN cord-354133-11b0d499 195 4 June June NNP cord-354133-11b0d499 195 5 , , , cord-354133-11b0d499 195 6 most most JJS cord-354133-11b0d499 195 7 of of IN cord-354133-11b0d499 195 8 Australia Australia NNP cord-354133-11b0d499 195 9 's 's POS cord-354133-11b0d499 195 10 COVID-19 covid-19 CD cord-354133-11b0d499 195 11 cases case NNS cord-354133-11b0d499 195 12 were be VBD cord-354133-11b0d499 195 13 returned return VBN cord-354133-11b0d499 195 14 travellers traveller NNS cord-354133-11b0d499 195 15 , , , cord-354133-11b0d499 195 16 which which WDT cord-354133-11b0d499 195 17 may may MD cord-354133-11b0d499 195 18 affect affect VB cord-354133-11b0d499 195 19 the the DT cord-354133-11b0d499 195 20 age age NN cord-354133-11b0d499 195 21 distribution distribution NN cord-354133-11b0d499 195 22 and and CC cord-354133-11b0d499 195 23 baseline baseline JJ cord-354133-11b0d499 195 24 health health NN cord-354133-11b0d499 195 25 of of IN cord-354133-11b0d499 195 26 cases case NNS cord-354133-11b0d499 195 27 compared compare VBN cord-354133-11b0d499 195 28 to to IN cord-354133-11b0d499 195 29 the the DT cord-354133-11b0d499 195 30 general general JJ cord-354133-11b0d499 195 31 population population NN cord-354133-11b0d499 195 32 . . . cord-354133-11b0d499 196 1 New New NNP cord-354133-11b0d499 196 2 Zealand Zealand NNP cord-354133-11b0d499 196 3 , , , cord-354133-11b0d499 196 4 Taiwan Taiwan NNP cord-354133-11b0d499 196 5 and and CC cord-354133-11b0d499 196 6 Thailand Thailand NNP cord-354133-11b0d499 196 7 are be VBP cord-354133-11b0d499 196 8 similarly similarly RB cord-354133-11b0d499 196 9 circumstanced circumstance VBN cord-354133-11b0d499 196 10 and and CC cord-354133-11b0d499 196 11 have have VBP cord-354133-11b0d499 196 12 very very RB cord-354133-11b0d499 196 13 similar similar JJ cord-354133-11b0d499 196 14 CFR CFR NNP cord-354133-11b0d499 196 15 values value NNS cord-354133-11b0d499 196 16 , , , cord-354133-11b0d499 196 17 which which WDT cord-354133-11b0d499 196 18 are be VBP cord-354133-11b0d499 196 19 expected expect VBN cord-354133-11b0d499 196 20 to to TO cord-354133-11b0d499 196 21 reflect reflect VB cord-354133-11b0d499 196 22 similar similar JJ cord-354133-11b0d499 196 23 IFR IFR NNP cord-354133-11b0d499 196 24 values value NNS cord-354133-11b0d499 196 25 to to IN cord-354133-11b0d499 196 26 Australia Australia NNP cord-354133-11b0d499 196 27 . . . cord-354133-11b0d499 197 1 Singapore Singapore NNP cord-354133-11b0d499 197 2 , , , cord-354133-11b0d499 197 3 with with IN cord-354133-11b0d499 197 4 its -PRON- PRP$ cord-354133-11b0d499 197 5 extremely extremely RB cord-354133-11b0d499 197 6 low low JJ cord-354133-11b0d499 197 7 fatalities fatality NNS cord-354133-11b0d499 197 8 and and CC cord-354133-11b0d499 197 9 extensive extensive JJ cord-354133-11b0d499 197 10 testing testing NN cord-354133-11b0d499 197 11 , , , cord-354133-11b0d499 197 12 did do VBD cord-354133-11b0d499 197 13 . . . cord-354133-11b0d499 198 1 CC CC NNP cord-354133-11b0d499 198 2 - - HYPH cord-354133-11b0d499 198 3 BY BY NNP cord-354133-11b0d499 198 4 - - HYPH cord-354133-11b0d499 198 5 NC NC NNP cord-354133-11b0d499 198 6 - - HYPH cord-354133-11b0d499 198 7 ND ND NNP cord-354133-11b0d499 198 8 4.0 4.0 CD cord-354133-11b0d499 198 9 International international JJ cord-354133-11b0d499 198 10 license license NN cord-354133-11b0d499 198 11 It -PRON- PRP cord-354133-11b0d499 198 12 is be VBZ cord-354133-11b0d499 198 13 made make VBN cord-354133-11b0d499 198 14 available available JJ cord-354133-11b0d499 198 15 under under IN cord-354133-11b0d499 198 16 a a DT cord-354133-11b0d499 198 17 perpetuity perpetuity NN cord-354133-11b0d499 198 18 . . . cord-354133-11b0d499 199 1 is be VBZ cord-354133-11b0d499 199 2 the the DT cord-354133-11b0d499 199 3 author author NN cord-354133-11b0d499 199 4 / / SYM cord-354133-11b0d499 199 5 funder funder NN cord-354133-11b0d499 199 6 , , , cord-354133-11b0d499 199 7 who who WP cord-354133-11b0d499 199 8 has have VBZ cord-354133-11b0d499 199 9 granted grant VBN cord-354133-11b0d499 199 10 medRxiv medRxiv NNS cord-354133-11b0d499 199 11 a a DT cord-354133-11b0d499 199 12 license license NN cord-354133-11b0d499 199 13 to to TO cord-354133-11b0d499 199 14 display display VB cord-354133-11b0d499 199 15 the the DT cord-354133-11b0d499 199 16 preprint preprint NN cord-354133-11b0d499 199 17 in in IN cord-354133-11b0d499 199 18 ( ( -LRB- cord-354133-11b0d499 199 19 which which WDT cord-354133-11b0d499 199 20 was be VBD cord-354133-11b0d499 199 21 not not RB cord-354133-11b0d499 199 22 certified certify VBN cord-354133-11b0d499 199 23 by by IN cord-354133-11b0d499 199 24 peer peer NN cord-354133-11b0d499 199 25 review review NN cord-354133-11b0d499 199 26 ) ) -RRB- cord-354133-11b0d499 199 27 preprint preprint NN cord-354133-11b0d499 200 1 The the DT cord-354133-11b0d499 200 2 copyright copyright NN cord-354133-11b0d499 200 3 holder holder NN cord-354133-11b0d499 200 4 for for IN cord-354133-11b0d499 200 5 this this DT cord-354133-11b0d499 200 6 this this DT cord-354133-11b0d499 200 7 version version NN cord-354133-11b0d499 200 8 posted post VBD cord-354133-11b0d499 200 9 October October NNP cord-354133-11b0d499 200 10 27 27 CD cord-354133-11b0d499 200 11 , , , cord-354133-11b0d499 200 12 2020 2020 CD cord-354133-11b0d499 200 13 . . . cord-354133-11b0d499 201 1 ; ; : cord-354133-11b0d499 201 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 201 3 doi doi NN cord-354133-11b0d499 201 4 : : : cord-354133-11b0d499 201 5 medRxiv medRxiv NNS cord-354133-11b0d499 201 6 preprint preprint NN cord-354133-11b0d499 201 7 not not RB cord-354133-11b0d499 201 8 return return VBP cord-354133-11b0d499 201 9 a a DT cord-354133-11b0d499 201 10 robust robust JJ cord-354133-11b0d499 201 11 result result NN cord-354133-11b0d499 201 12 from from IN cord-354133-11b0d499 201 13 TSD TSD NNP cord-354133-11b0d499 201 14 analysis analysis NN cord-354133-11b0d499 201 15 ; ; : cord-354133-11b0d499 201 16 nonetheless nonetheless RB cord-354133-11b0d499 201 17 , , , cord-354133-11b0d499 201 18 the the DT cord-354133-11b0d499 201 19 crude crude JJ cord-354133-11b0d499 201 20 CFR CFR NNP cord-354133-11b0d499 201 21 of of IN cord-354133-11b0d499 201 22 0.07 0.07 CD cord-354133-11b0d499 201 23 % % NN cord-354133-11b0d499 201 24 at at IN cord-354133-11b0d499 201 25 the the DT cord-354133-11b0d499 201 26 end end NN cord-354133-11b0d499 201 27 of of IN cord-354133-11b0d499 201 28 May May NNP cord-354133-11b0d499 201 29 is be VBZ cord-354133-11b0d499 201 30 likely likely RB cord-354133-11b0d499 201 31 a a DT cord-354133-11b0d499 201 32 lower lower RBR cord-354133-11b0d499 201 33 bound bind VBN cord-354133-11b0d499 201 34 for for IN cord-354133-11b0d499 201 35 the the DT cord-354133-11b0d499 201 36 IFR IFR NNP cord-354133-11b0d499 201 37 . . . cord-354133-11b0d499 202 1 The the DT cord-354133-11b0d499 202 2 USA USA NNP cord-354133-11b0d499 202 3 is be VBZ cord-354133-11b0d499 202 4 an an DT cord-354133-11b0d499 202 5 interesting interesting JJ cord-354133-11b0d499 202 6 case case NN cord-354133-11b0d499 202 7 study study NN cord-354133-11b0d499 202 8 . . . cord-354133-11b0d499 203 1 The the DT cord-354133-11b0d499 203 2 TSD TSD NNP cord-354133-11b0d499 203 3 analysis analysis NN cord-354133-11b0d499 203 4 is be VBZ cord-354133-11b0d499 203 5 problematic problematic JJ cord-354133-11b0d499 203 6 because because IN cord-354133-11b0d499 203 7 the the DT cord-354133-11b0d499 203 8 relationship relationship NN cord-354133-11b0d499 203 9 between between IN cord-354133-11b0d499 203 10 cases case NNS cord-354133-11b0d499 203 11 and and CC cord-354133-11b0d499 203 12 deaths death NNS cord-354133-11b0d499 203 13 changes change NNS cord-354133-11b0d499 203 14 over over IN cord-354133-11b0d499 203 15 time time NN cord-354133-11b0d499 203 16 , , , cord-354133-11b0d499 203 17 causing cause VBG cord-354133-11b0d499 203 18 mismatch mismatch NN cord-354133-11b0d499 203 19 between between IN cord-354133-11b0d499 203 20 case case NN cord-354133-11b0d499 203 21 and and CC cord-354133-11b0d499 203 22 death death NN cord-354133-11b0d499 203 23 distributions distribution NNS cord-354133-11b0d499 203 24 and and CC cord-354133-11b0d499 203 25 a a DT cord-354133-11b0d499 203 26 downward downward JJ cord-354133-11b0d499 203 27 drift drift NN cord-354133-11b0d499 203 28 in in IN cord-354133-11b0d499 203 29 both both DT cord-354133-11b0d499 203 30 CFR CFR NNP cord-354133-11b0d499 203 31 and and CC cord-354133-11b0d499 203 32 delay delay NN cord-354133-11b0d499 203 33 time time NN cord-354133-11b0d499 203 34 . . . cord-354133-11b0d499 204 1 This this DT cord-354133-11b0d499 204 2 may may MD cord-354133-11b0d499 204 3 be be VB cord-354133-11b0d499 204 4 due due JJ cord-354133-11b0d499 204 5 to to IN cord-354133-11b0d499 204 6 incomplete incomplete JJ cord-354133-11b0d499 204 7 data datum NNS cord-354133-11b0d499 204 8 , , , cord-354133-11b0d499 204 9 or or CC cord-354133-11b0d499 204 10 changes change NNS cord-354133-11b0d499 204 11 in in IN cord-354133-11b0d499 204 12 testing testing NN cord-354133-11b0d499 204 13 or or CC cord-354133-11b0d499 204 14 reporting report VBG cord-354133-11b0d499 204 15 over over IN cord-354133-11b0d499 204 16 time time NN cord-354133-11b0d499 204 17 , , , cord-354133-11b0d499 204 18 which which WDT cord-354133-11b0d499 204 19 can can MD cord-354133-11b0d499 204 20 affect affect VB cord-354133-11b0d499 204 21 both both DT cord-354133-11b0d499 204 22 delay delay NN cord-354133-11b0d499 204 23 time time NN cord-354133-11b0d499 204 24 and and CC cord-354133-11b0d499 204 25 case case NN cord-354133-11b0d499 204 26 numbers number NNS cord-354133-11b0d499 204 27 . . . cord-354133-11b0d499 205 1 Alternatively alternatively RB cord-354133-11b0d499 205 2 , , , cord-354133-11b0d499 205 3 the the DT cord-354133-11b0d499 205 4 case case NN cord-354133-11b0d499 205 5 fatality fatality NN cord-354133-11b0d499 205 6 ratio ratio NN cord-354133-11b0d499 205 7 may may MD cord-354133-11b0d499 205 8 be be VB cord-354133-11b0d499 205 9 truly truly RB cord-354133-11b0d499 205 10 changing change VBG cord-354133-11b0d499 205 11 over over IN cord-354133-11b0d499 205 12 time time NN cord-354133-11b0d499 205 13 , , , cord-354133-11b0d499 205 14 due due IN cord-354133-11b0d499 205 15 to to IN cord-354133-11b0d499 205 16 changes change NNS cord-354133-11b0d499 205 17 in in IN cord-354133-11b0d499 205 18 treatment treatment NN cord-354133-11b0d499 205 19 approach approach NN cord-354133-11b0d499 205 20 or or CC cord-354133-11b0d499 205 21 in in IN cord-354133-11b0d499 205 22 the the DT cord-354133-11b0d499 205 23 demographics demographic NNS cord-354133-11b0d499 205 24 ( ( -LRB- cord-354133-11b0d499 205 25 or or CC cord-354133-11b0d499 205 26 location location NN cord-354133-11b0d499 205 27 ) ) -RRB- cord-354133-11b0d499 205 28 of of IN cord-354133-11b0d499 206 1 COVID-19 covid-19 JJ cord-354133-11b0d499 206 2 cases case NNS cord-354133-11b0d499 206 3 [ [ -LRB- cord-354133-11b0d499 206 4 32 32 CD cord-354133-11b0d499 206 5 ] ] -RRB- cord-354133-11b0d499 206 6 . . . cord-354133-11b0d499 207 1 In in IN cord-354133-11b0d499 207 2 the the DT cord-354133-11b0d499 207 3 USA USA NNP cord-354133-11b0d499 207 4 , , , cord-354133-11b0d499 207 5 there there EX cord-354133-11b0d499 207 6 is be VBZ cord-354133-11b0d499 207 7 also also RB cord-354133-11b0d499 207 8 heterogeneity heterogeneity NN cord-354133-11b0d499 207 9 between between IN cord-354133-11b0d499 207 10 states state NNS cord-354133-11b0d499 207 11 . . . cord-354133-11b0d499 208 1 To to TO cord-354133-11b0d499 208 2 demonstrate demonstrate VB cord-354133-11b0d499 208 3 , , , cord-354133-11b0d499 208 4 we -PRON- PRP cord-354133-11b0d499 208 5 present present VBP cord-354133-11b0d499 208 6 the the DT cord-354133-11b0d499 208 7 time time NN cord-354133-11b0d499 208 8 - - HYPH cord-354133-11b0d499 208 9 shifted shift VBN cord-354133-11b0d499 208 10 distribution distribution NN cord-354133-11b0d499 208 11 analysis analysis NN cord-354133-11b0d499 208 12 for for IN cord-354133-11b0d499 208 13 the the DT cord-354133-11b0d499 208 14 USA USA NNP cord-354133-11b0d499 208 15 in in IN cord-354133-11b0d499 208 16 Figure Figure NNP cord-354133-11b0d499 208 17 7 7 CD cord-354133-11b0d499 208 18 , , , cord-354133-11b0d499 208 19 and and CC cord-354133-11b0d499 208 20 for for IN cord-354133-11b0d499 208 21 the the DT cord-354133-11b0d499 208 22 state state NN cord-354133-11b0d499 208 23 of of IN cord-354133-11b0d499 208 24 New New NNP cord-354133-11b0d499 208 25 Jersey Jersey NNP cord-354133-11b0d499 208 26 ( ( -LRB- cord-354133-11b0d499 208 27 which which WDT cord-354133-11b0d499 208 28 has have VBZ cord-354133-11b0d499 208 29 the the DT cord-354133-11b0d499 208 30 highest high JJS cord-354133-11b0d499 208 31 mortality mortality NN cord-354133-11b0d499 208 32 rate rate NN cord-354133-11b0d499 208 33 in in IN cord-354133-11b0d499 208 34 the the DT cord-354133-11b0d499 208 35 USA USA NNP cord-354133-11b0d499 208 36 ) ) -RRB- cord-354133-11b0d499 208 37 in in IN cord-354133-11b0d499 208 38 and and CC cord-354133-11b0d499 208 39 Illinois Illinois NNP cord-354133-11b0d499 208 40 and and CC cord-354133-11b0d499 208 41 New New NNP cord-354133-11b0d499 208 42 Mexico Mexico NNP cord-354133-11b0d499 208 43 give give VBP cord-354133-11b0d499 208 44 5 5 CD cord-354133-11b0d499 208 45 % % NN cord-354133-11b0d499 208 46 . . . cord-354133-11b0d499 209 1 One one CD cord-354133-11b0d499 209 2 potential potential JJ cord-354133-11b0d499 209 3 reason reason NN cord-354133-11b0d499 209 4 for for IN cord-354133-11b0d499 209 5 the the DT cord-354133-11b0d499 209 6 mismatch mismatch NN cord-354133-11b0d499 209 7 of of IN cord-354133-11b0d499 209 8 case case NN cord-354133-11b0d499 209 9 and and CC cord-354133-11b0d499 209 10 death death NN cord-354133-11b0d499 209 11 data datum NNS cord-354133-11b0d499 209 12 in in IN cord-354133-11b0d499 209 13 the the DT cord-354133-11b0d499 209 14 USA USA NNP cord-354133-11b0d499 209 15 as as IN cord-354133-11b0d499 209 16 a a DT cord-354133-11b0d499 209 17 whole whole NN cord-354133-11b0d499 209 18 ( ( -LRB- cord-354133-11b0d499 209 19 and and CC cord-354133-11b0d499 209 20 many many JJ cord-354133-11b0d499 209 21 of of IN cord-354133-11b0d499 209 22 its -PRON- PRP$ cord-354133-11b0d499 209 23 states state NNS cord-354133-11b0d499 209 24 ) ) -RRB- cord-354133-11b0d499 209 25 is be VBZ cord-354133-11b0d499 209 26 the the DT cord-354133-11b0d499 209 27 under under NN cord-354133-11b0d499 209 28 - - HYPH cord-354133-11b0d499 209 29 reporting reporting NN cord-354133-11b0d499 209 30 of of IN cord-354133-11b0d499 209 31 cases case NNS cord-354133-11b0d499 209 32 due due JJ cord-354133-11b0d499 209 33 to to IN cord-354133-11b0d499 209 34 the the DT cord-354133-11b0d499 209 35 low low JJ cord-354133-11b0d499 209 36 level level NN cord-354133-11b0d499 209 37 of of IN cord-354133-11b0d499 209 38 testing testing NN cord-354133-11b0d499 209 39 , , , cord-354133-11b0d499 209 40 which which WDT cord-354133-11b0d499 209 41 varies vary VBZ cord-354133-11b0d499 209 42 over over IN cord-354133-11b0d499 209 43 time time NN cord-354133-11b0d499 209 44 . . . cord-354133-11b0d499 210 1 One one CD cord-354133-11b0d499 210 2 measure measure NN cord-354133-11b0d499 210 3 of of IN cord-354133-11b0d499 210 4 the the DT cord-354133-11b0d499 210 5 adequacy adequacy NN cord-354133-11b0d499 210 6 of of IN cord-354133-11b0d499 210 7 testing testing NN cord-354133-11b0d499 210 8 is be VBZ cord-354133-11b0d499 210 9 the the DT cord-354133-11b0d499 210 10 share share NN cord-354133-11b0d499 210 11 of of IN cord-354133-11b0d499 210 12 daily daily JJ cord-354133-11b0d499 210 13 COVID-19 covid-19 JJ cord-354133-11b0d499 210 14 tests test NNS cord-354133-11b0d499 210 15 that that WDT cord-354133-11b0d499 210 16 return return VBP cord-354133-11b0d499 210 17 a a DT cord-354133-11b0d499 210 18 positive positive JJ cord-354133-11b0d499 210 19 result result NN cord-354133-11b0d499 210 20 , , , cord-354133-11b0d499 210 21 known know VBN cord-354133-11b0d499 210 22 as as IN cord-354133-11b0d499 210 23 the the DT cord-354133-11b0d499 210 24 positive positive JJ cord-354133-11b0d499 210 25 test test NN cord-354133-11b0d499 210 26 rate rate NN cord-354133-11b0d499 210 27 ( ( -LRB- cord-354133-11b0d499 210 28 PTR ptr NN cord-354133-11b0d499 210 29 ) ) -RRB- cord-354133-11b0d499 210 30 . . . cord-354133-11b0d499 211 1 The the DT cord-354133-11b0d499 211 2 WHO who WP cord-354133-11b0d499 211 3 has have VBZ cord-354133-11b0d499 211 4 suggested suggest VBN cord-354133-11b0d499 211 5 a a DT cord-354133-11b0d499 211 6 PTR ptr NN cord-354133-11b0d499 211 7 around around IN cord-354133-11b0d499 211 8 3 3 CD cord-354133-11b0d499 211 9 - - SYM cord-354133-11b0d499 211 10 12 12 CD cord-354133-11b0d499 211 11 % % NN cord-354133-11b0d499 211 12 ( ( -LRB- cord-354133-11b0d499 211 13 or or CC cord-354133-11b0d499 211 14 less less RBR cord-354133-11b0d499 211 15 ) ) -RRB- cord-354133-11b0d499 211 16 as as IN cord-354133-11b0d499 211 17 a a DT cord-354133-11b0d499 211 18 benchmark benchmark NN cord-354133-11b0d499 211 19 of of IN cord-354133-11b0d499 211 20 adequate adequate JJ cord-354133-11b0d499 211 21 testing testing NN cord-354133-11b0d499 211 22 [ [ -LRB- cord-354133-11b0d499 211 23 33 33 CD cord-354133-11b0d499 211 24 ] ] -RRB- cord-354133-11b0d499 211 25 . . . cord-354133-11b0d499 212 1 In in IN cord-354133-11b0d499 212 2 the the DT cord-354133-11b0d499 212 3 USA USA NNP cord-354133-11b0d499 212 4 , , , cord-354133-11b0d499 212 5 the the DT cord-354133-11b0d499 212 6 positive positive JJ cord-354133-11b0d499 212 7 test test NN cord-354133-11b0d499 212 8 rate rate NN cord-354133-11b0d499 212 9 reached reach VBD cord-354133-11b0d499 212 10 maximum maximum JJ cord-354133-11b0d499 212 11 levels level NNS cord-354133-11b0d499 212 12 in in IN cord-354133-11b0d499 212 13 April April NNP cord-354133-11b0d499 212 14 , , , cord-354133-11b0d499 212 15 with with IN cord-354133-11b0d499 212 16 values value NNS cord-354133-11b0d499 212 17 between between IN cord-354133-11b0d499 212 18 18 18 CD cord-354133-11b0d499 212 19 and and CC cord-354133-11b0d499 212 20 22 22 CD cord-354133-11b0d499 212 21 % % NN cord-354133-11b0d499 212 22 from from IN cord-354133-11b0d499 212 23 1 1 CD cord-354133-11b0d499 212 24 - - SYM cord-354133-11b0d499 212 25 21 21 CD cord-354133-11b0d499 212 26 April April NNP cord-354133-11b0d499 212 27 [ [ -LRB- cord-354133-11b0d499 212 28 33 33 CD cord-354133-11b0d499 212 29 ] ] -RRB- cord-354133-11b0d499 212 30 , , , cord-354133-11b0d499 212 31 is be VBZ cord-354133-11b0d499 212 32 the the DT cord-354133-11b0d499 212 33 author author NN cord-354133-11b0d499 212 34 / / SYM cord-354133-11b0d499 212 35 funder funder NN cord-354133-11b0d499 212 36 , , , cord-354133-11b0d499 212 37 who who WP cord-354133-11b0d499 212 38 has have VBZ cord-354133-11b0d499 212 39 granted grant VBN cord-354133-11b0d499 212 40 medRxiv medRxiv NNS cord-354133-11b0d499 212 41 a a DT cord-354133-11b0d499 212 42 license license NN cord-354133-11b0d499 212 43 to to TO cord-354133-11b0d499 212 44 display display VB cord-354133-11b0d499 212 45 the the DT cord-354133-11b0d499 212 46 preprint preprint NN cord-354133-11b0d499 212 47 in in IN cord-354133-11b0d499 212 48 ( ( -LRB- cord-354133-11b0d499 212 49 which which WDT cord-354133-11b0d499 212 50 was be VBD cord-354133-11b0d499 212 51 not not RB cord-354133-11b0d499 212 52 certified certify VBN cord-354133-11b0d499 212 53 by by IN cord-354133-11b0d499 212 54 peer peer NN cord-354133-11b0d499 212 55 review review NN cord-354133-11b0d499 212 56 ) ) -RRB- cord-354133-11b0d499 212 57 preprint preprint NN cord-354133-11b0d499 213 1 The the DT cord-354133-11b0d499 213 2 copyright copyright NN cord-354133-11b0d499 213 3 holder holder NN cord-354133-11b0d499 213 4 for for IN cord-354133-11b0d499 213 5 this this DT cord-354133-11b0d499 213 6 this this DT cord-354133-11b0d499 213 7 version version NN cord-354133-11b0d499 213 8 posted post VBD cord-354133-11b0d499 213 9 October October NNP cord-354133-11b0d499 213 10 27 27 CD cord-354133-11b0d499 213 11 , , , cord-354133-11b0d499 213 12 2020 2020 CD cord-354133-11b0d499 213 13 . . . cord-354133-11b0d499 214 1 which which WDT cord-354133-11b0d499 214 2 is be VBZ cord-354133-11b0d499 214 3 the the DT cord-354133-11b0d499 214 4 region region NN cord-354133-11b0d499 214 5 of of IN cord-354133-11b0d499 214 6 greatest great JJS cord-354133-11b0d499 214 7 discrepancy discrepancy NN cord-354133-11b0d499 214 8 between between IN cord-354133-11b0d499 214 9 case case NN cord-354133-11b0d499 214 10 and and CC cord-354133-11b0d499 214 11 death death NN cord-354133-11b0d499 214 12 profiles profile NNS cord-354133-11b0d499 214 13 in in IN cord-354133-11b0d499 214 14 the the DT cord-354133-11b0d499 214 15 initial initial JJ cord-354133-11b0d499 214 16 outbreak outbreak NN cord-354133-11b0d499 214 17 , , , cord-354133-11b0d499 214 18 as as IN cord-354133-11b0d499 214 19 seen see VBN cord-354133-11b0d499 214 20 in in IN cord-354133-11b0d499 214 21 Figure Figure NNP cord-354133-11b0d499 214 22 7 7 CD cord-354133-11b0d499 214 23 . . . cord-354133-11b0d499 215 1 We -PRON- PRP cord-354133-11b0d499 215 2 would would MD cord-354133-11b0d499 215 3 expect expect VB cord-354133-11b0d499 215 4 that that IN cord-354133-11b0d499 215 5 such such PDT cord-354133-11b0d499 215 6 a a DT cord-354133-11b0d499 215 7 high high JJ cord-354133-11b0d499 215 8 PTR ptr NN cord-354133-11b0d499 215 9 indicates indicate VBZ cord-354133-11b0d499 215 10 that that IN cord-354133-11b0d499 215 11 case case NN cord-354133-11b0d499 215 12 numbers number NNS cord-354133-11b0d499 215 13 during during IN cord-354133-11b0d499 215 14 this this DT cord-354133-11b0d499 215 15 time time NN cord-354133-11b0d499 215 16 are be VBP cord-354133-11b0d499 215 17 greatly greatly RB cord-354133-11b0d499 215 18 underestimated underestimate VBN cord-354133-11b0d499 215 19 , , , cord-354133-11b0d499 215 20 which which WDT cord-354133-11b0d499 215 21 may may MD cord-354133-11b0d499 215 22 explain explain VB cord-354133-11b0d499 215 23 the the DT cord-354133-11b0d499 215 24 poor poor JJ cord-354133-11b0d499 215 25 fit fit NN cord-354133-11b0d499 215 26 from from IN cord-354133-11b0d499 215 27 TSD TSD NNP cord-354133-11b0d499 215 28 analysis analysis NN cord-354133-11b0d499 215 29 and and CC cord-354133-11b0d499 215 30 the the DT cord-354133-11b0d499 215 31 high high JJ cord-354133-11b0d499 215 32 CFR CFR NNP cord-354133-11b0d499 215 33 . . . cord-354133-11b0d499 216 1 Similar similar JJ cord-354133-11b0d499 216 2 effects effect NNS cord-354133-11b0d499 216 3 are be VBP cord-354133-11b0d499 216 4 seen see VBN cord-354133-11b0d499 216 5 in in IN cord-354133-11b0d499 216 6 data datum NNS cord-354133-11b0d499 216 7 from from IN cord-354133-11b0d499 216 8 Sweden Sweden NNP cord-354133-11b0d499 216 9 and and CC cord-354133-11b0d499 216 10 Brazil Brazil NNP cord-354133-11b0d499 216 11 , , , cord-354133-11b0d499 216 12 which which WDT cord-354133-11b0d499 216 13 also also RB cord-354133-11b0d499 216 14 had have VBD cord-354133-11b0d499 216 15 low low JJ cord-354133-11b0d499 216 16 and and CC cord-354133-11b0d499 216 17 variable variable JJ cord-354133-11b0d499 216 18 testing testing NN cord-354133-11b0d499 216 19 rates rate NNS cord-354133-11b0d499 216 20 and and CC cord-354133-11b0d499 216 21 high high JJ cord-354133-11b0d499 216 22 PTR ptr NN cord-354133-11b0d499 216 23 . . . cord-354133-11b0d499 217 1 Recent recent JJ cord-354133-11b0d499 217 2 seroprevalence seroprevalence NN cord-354133-11b0d499 217 3 studies study NNS cord-354133-11b0d499 217 4 in in IN cord-354133-11b0d499 217 5 many many JJ cord-354133-11b0d499 217 6 states state NNS cord-354133-11b0d499 217 7 . . . cord-354133-11b0d499 218 1 CC CC NNP cord-354133-11b0d499 218 2 - - HYPH cord-354133-11b0d499 218 3 BY BY NNP cord-354133-11b0d499 218 4 - - HYPH cord-354133-11b0d499 218 5 NC NC NNP cord-354133-11b0d499 218 6 - - HYPH cord-354133-11b0d499 218 7 ND ND NNP cord-354133-11b0d499 218 8 4.0 4.0 CD cord-354133-11b0d499 218 9 International international JJ cord-354133-11b0d499 218 10 license license NN cord-354133-11b0d499 218 11 It -PRON- PRP cord-354133-11b0d499 218 12 is be VBZ cord-354133-11b0d499 218 13 made make VBN cord-354133-11b0d499 218 14 available available JJ cord-354133-11b0d499 218 15 under under IN cord-354133-11b0d499 218 16 a a DT cord-354133-11b0d499 218 17 perpetuity perpetuity NN cord-354133-11b0d499 218 18 . . . cord-354133-11b0d499 219 1 is be VBZ cord-354133-11b0d499 219 2 the the DT cord-354133-11b0d499 219 3 author author NN cord-354133-11b0d499 219 4 / / SYM cord-354133-11b0d499 219 5 funder funder NN cord-354133-11b0d499 219 6 , , , cord-354133-11b0d499 219 7 who who WP cord-354133-11b0d499 219 8 has have VBZ cord-354133-11b0d499 219 9 granted grant VBN cord-354133-11b0d499 219 10 medRxiv medRxiv NNS cord-354133-11b0d499 219 11 a a DT cord-354133-11b0d499 219 12 license license NN cord-354133-11b0d499 219 13 to to TO cord-354133-11b0d499 219 14 display display VB cord-354133-11b0d499 219 15 the the DT cord-354133-11b0d499 219 16 preprint preprint NN cord-354133-11b0d499 219 17 in in IN cord-354133-11b0d499 219 18 ( ( -LRB- cord-354133-11b0d499 219 19 which which WDT cord-354133-11b0d499 219 20 was be VBD cord-354133-11b0d499 219 21 not not RB cord-354133-11b0d499 219 22 certified certify VBN cord-354133-11b0d499 219 23 by by IN cord-354133-11b0d499 219 24 peer peer NN cord-354133-11b0d499 219 25 review review NN cord-354133-11b0d499 219 26 ) ) -RRB- cord-354133-11b0d499 219 27 preprint preprint NN cord-354133-11b0d499 220 1 The the DT cord-354133-11b0d499 220 2 copyright copyright NN cord-354133-11b0d499 220 3 holder holder NN cord-354133-11b0d499 220 4 for for IN cord-354133-11b0d499 220 5 this this DT cord-354133-11b0d499 220 6 this this DT cord-354133-11b0d499 220 7 version version NN cord-354133-11b0d499 220 8 posted post VBD cord-354133-11b0d499 220 9 October October NNP cord-354133-11b0d499 220 10 27 27 CD cord-354133-11b0d499 220 11 , , , cord-354133-11b0d499 220 12 2020 2020 CD cord-354133-11b0d499 220 13 . . . cord-354133-11b0d499 221 1 ; ; : cord-354133-11b0d499 221 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 221 3 doi doi NN cord-354133-11b0d499 221 4 : : : cord-354133-11b0d499 222 1 medRxiv medRxiv NNP cord-354133-11b0d499 222 2 preprint preprint NN cord-354133-11b0d499 222 3 of of IN cord-354133-11b0d499 222 4 the the DT cord-354133-11b0d499 222 5 USA USA NNP cord-354133-11b0d499 222 6 from from IN cord-354133-11b0d499 222 7 March March NNP cord-354133-11b0d499 222 8 to to IN cord-354133-11b0d499 222 9 May May NNP cord-354133-11b0d499 222 10 [ [ -LRB- cord-354133-11b0d499 222 11 34 34 CD cord-354133-11b0d499 222 12 ] ] -RRB- cord-354133-11b0d499 222 13 suggest suggest VBP cord-354133-11b0d499 222 14 that that IN cord-354133-11b0d499 222 15 there there EX cord-354133-11b0d499 222 16 were be VBD cord-354133-11b0d499 222 17 at at RB cord-354133-11b0d499 222 18 least least RBS cord-354133-11b0d499 222 19 eleven eleven CD cord-354133-11b0d499 222 20 times time NNS cord-354133-11b0d499 222 21 as as IN cord-354133-11b0d499 222 22 many many JJ cord-354133-11b0d499 222 23 infections infection NNS cord-354133-11b0d499 222 24 as as IN cord-354133-11b0d499 222 25 reported report VBN cord-354133-11b0d499 222 26 cases case NNS cord-354133-11b0d499 222 27 before before IN cord-354133-11b0d499 222 28 the the DT cord-354133-11b0d499 222 29 end end NN cord-354133-11b0d499 222 30 of of IN cord-354133-11b0d499 222 31 May. May NNP cord-354133-11b0d499 222 32 Excess Excess NNP cord-354133-11b0d499 222 33 death death NN cord-354133-11b0d499 222 34 data datum NNS cord-354133-11b0d499 222 35 indicate indicate VBP cord-354133-11b0d499 222 36 that that IN cord-354133-11b0d499 222 37 COVIDrelated covidrelate VBN cord-354133-11b0d499 222 38 deaths death NNS cord-354133-11b0d499 222 39 may may MD cord-354133-11b0d499 222 40 be be VB cord-354133-11b0d499 222 41 higher high JJR cord-354133-11b0d499 222 42 than than IN cord-354133-11b0d499 222 43 reported report VBN cord-354133-11b0d499 222 44 by by IN cord-354133-11b0d499 222 45 a a DT cord-354133-11b0d499 222 46 factor factor NN cord-354133-11b0d499 222 47 of of IN cord-354133-11b0d499 222 48 1.4 1.4 CD cord-354133-11b0d499 222 49 for for IN cord-354133-11b0d499 222 50 the the DT cord-354133-11b0d499 222 51 same same JJ cord-354133-11b0d499 222 52 period period NN cord-354133-11b0d499 222 53 [ [ -LRB- cord-354133-11b0d499 222 54 35 35 CD cord-354133-11b0d499 222 55 ] ] -RRB- cord-354133-11b0d499 222 56 . . . cord-354133-11b0d499 223 1 Using use VBG cord-354133-11b0d499 223 2 these these DT cord-354133-11b0d499 223 3 correction correction NN cord-354133-11b0d499 223 4 factors factor NNS cord-354133-11b0d499 223 5 for for IN cord-354133-11b0d499 223 6 the the DT cord-354133-11b0d499 223 7 CFR CFR NNP cord-354133-11b0d499 223 8 , , , cord-354133-11b0d499 223 9 the the DT cord-354133-11b0d499 223 10 estimated estimate VBN cord-354133-11b0d499 223 11 IFR IFR NNP cord-354133-11b0d499 223 12 for for IN cord-354133-11b0d499 223 13 the the DT cord-354133-11b0d499 223 14 USA USA NNP cord-354133-11b0d499 223 15 is be VBZ cord-354133-11b0d499 223 16 1.0 1.0 CD cord-354133-11b0d499 223 17 % % NN cord-354133-11b0d499 223 18 or or CC cord-354133-11b0d499 223 19 below below RB cord-354133-11b0d499 223 20 . . . cord-354133-11b0d499 224 1 For for IN cord-354133-11b0d499 224 2 is be VBZ cord-354133-11b0d499 224 3 the the DT cord-354133-11b0d499 224 4 author author NN cord-354133-11b0d499 224 5 / / SYM cord-354133-11b0d499 224 6 funder funder NN cord-354133-11b0d499 224 7 , , , cord-354133-11b0d499 224 8 who who WP cord-354133-11b0d499 224 9 has have VBZ cord-354133-11b0d499 224 10 granted grant VBN cord-354133-11b0d499 224 11 medRxiv medRxiv NNS cord-354133-11b0d499 224 12 a a DT cord-354133-11b0d499 224 13 license license NN cord-354133-11b0d499 224 14 to to TO cord-354133-11b0d499 224 15 display display VB cord-354133-11b0d499 224 16 the the DT cord-354133-11b0d499 224 17 preprint preprint NN cord-354133-11b0d499 224 18 in in IN cord-354133-11b0d499 224 19 ( ( -LRB- cord-354133-11b0d499 224 20 which which WDT cord-354133-11b0d499 224 21 was be VBD cord-354133-11b0d499 224 22 not not RB cord-354133-11b0d499 224 23 certified certify VBN cord-354133-11b0d499 224 24 by by IN cord-354133-11b0d499 224 25 peer peer NN cord-354133-11b0d499 224 26 review review NN cord-354133-11b0d499 224 27 ) ) -RRB- cord-354133-11b0d499 225 1 preprint preprint NN cord-354133-11b0d499 226 1 The the DT cord-354133-11b0d499 226 2 copyright copyright NN cord-354133-11b0d499 226 3 holder holder NN cord-354133-11b0d499 226 4 for for IN cord-354133-11b0d499 226 5 this this DT cord-354133-11b0d499 226 6 this this DT cord-354133-11b0d499 226 7 version version NN cord-354133-11b0d499 226 8 posted post VBD cord-354133-11b0d499 226 9 October October NNP cord-354133-11b0d499 226 10 27 27 CD cord-354133-11b0d499 226 11 , , , cord-354133-11b0d499 226 12 2020 2020 CD cord-354133-11b0d499 226 13 . . . cord-354133-11b0d499 227 1 ; ; : cord-354133-11b0d499 227 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 227 3 doi doi NN cord-354133-11b0d499 227 4 : : : cord-354133-11b0d499 228 1 medRxiv medRxiv NNP cord-354133-11b0d499 228 2 preprint preprint NN cord-354133-11b0d499 228 3 comparison comparison NN cord-354133-11b0d499 228 4 , , , cord-354133-11b0d499 228 5 a a DT cord-354133-11b0d499 228 6 Worldometers Worldometers NNP cord-354133-11b0d499 228 7 calculation calculation NN cord-354133-11b0d499 228 8 estimated estimate VBD cord-354133-11b0d499 228 9 an an DT cord-354133-11b0d499 228 10 IFR IFR NNP cord-354133-11b0d499 228 11 of of IN cord-354133-11b0d499 228 12 1.4 1.4 CD cord-354133-11b0d499 228 13 % % NN cord-354133-11b0d499 228 14 in in IN cord-354133-11b0d499 228 15 New New NNP cord-354133-11b0d499 228 16 York York NNP cord-354133-11b0d499 228 17 City City NNP cord-354133-11b0d499 228 18 in in IN cord-354133-11b0d499 228 19 May May NNP cord-354133-11b0d499 228 20 [ [ -LRB- cord-354133-11b0d499 228 21 23 23 CD cord-354133-11b0d499 228 22 ] ] -RRB- cord-354133-11b0d499 228 23 , , , cord-354133-11b0d499 228 24 using use VBG cord-354133-11b0d499 228 25 a a DT cord-354133-11b0d499 228 26 prevalence prevalence NN cord-354133-11b0d499 228 27 ratio ratio NN cord-354133-11b0d499 228 28 of of IN cord-354133-11b0d499 228 29 ten ten CD cord-354133-11b0d499 228 30 from from IN cord-354133-11b0d499 228 31 an an DT cord-354133-11b0d499 228 32 early early JJ cord-354133-11b0d499 228 33 antibody antibody NN cord-354133-11b0d499 228 34 study study NN cord-354133-11b0d499 228 35 [ [ -LRB- cord-354133-11b0d499 228 36 36 36 CD cord-354133-11b0d499 228 37 , , , cord-354133-11b0d499 228 38 37 37 CD cord-354133-11b0d499 228 39 ] ] -RRB- cord-354133-11b0d499 228 40 . . . cord-354133-11b0d499 229 1 In in IN cord-354133-11b0d499 229 2 Europe Europe NNP cord-354133-11b0d499 229 3 , , , cord-354133-11b0d499 229 4 many many JJ cord-354133-11b0d499 229 5 of of IN cord-354133-11b0d499 229 6 the the DT cord-354133-11b0d499 229 7 most most RBS cord-354133-11b0d499 229 8 affected affected JJ cord-354133-11b0d499 229 9 countries country NNS cord-354133-11b0d499 229 10 have have VBP cord-354133-11b0d499 229 11 very very RB cord-354133-11b0d499 229 12 high high JJ cord-354133-11b0d499 229 13 case case NN cord-354133-11b0d499 229 14 fatality fatality NN cord-354133-11b0d499 229 15 ratios ratio NNS cord-354133-11b0d499 229 16 , , , cord-354133-11b0d499 229 17 often often RB cord-354133-11b0d499 229 18 combined combine VBN cord-354133-11b0d499 229 19 with with IN cord-354133-11b0d499 229 20 relatively relatively RB cord-354133-11b0d499 229 21 short short JJ cord-354133-11b0d499 229 22 delay delay NN cord-354133-11b0d499 229 23 times time NNS cord-354133-11b0d499 229 24 . . . cord-354133-11b0d499 230 1 For for IN cord-354133-11b0d499 230 2 some some DT cord-354133-11b0d499 230 3 of of IN cord-354133-11b0d499 230 4 these these DT cord-354133-11b0d499 230 5 countries country NNS cord-354133-11b0d499 230 6 , , , cord-354133-11b0d499 230 7 seroprevalence seroprevalence NN cord-354133-11b0d499 230 8 studies study NNS cord-354133-11b0d499 230 9 provide provide VBP cord-354133-11b0d499 230 10 estimates estimate NNS cord-354133-11b0d499 230 11 of of IN cord-354133-11b0d499 230 12 the the DT cord-354133-11b0d499 230 13 degree degree NN cord-354133-11b0d499 230 14 of of IN cord-354133-11b0d499 230 15 undercounting undercounting NN cord-354133-11b0d499 230 16 of of IN cord-354133-11b0d499 230 17 cases case NNS cord-354133-11b0d499 230 18 during during IN cord-354133-11b0d499 230 19 the the DT cord-354133-11b0d499 230 20 initial initial JJ cord-354133-11b0d499 230 21 outbreak outbreak NN cord-354133-11b0d499 230 22 [ [ -LRB- cord-354133-11b0d499 230 23 38 38 CD cord-354133-11b0d499 230 24 ] ] -RRB- cord-354133-11b0d499 230 25 [ [ -LRB- cord-354133-11b0d499 230 26 39 39 CD cord-354133-11b0d499 230 27 ] ] -RRB- cord-354133-11b0d499 230 28 [ [ -LRB- cord-354133-11b0d499 230 29 40 40 CD cord-354133-11b0d499 230 30 ] ] -RRB- cord-354133-11b0d499 230 31 [ [ -LRB- cord-354133-11b0d499 230 32 41 41 CD cord-354133-11b0d499 230 33 ] ] -RRB- cord-354133-11b0d499 230 34 [ [ -LRB- cord-354133-11b0d499 230 35 42 42 CD cord-354133-11b0d499 230 36 ] ] -RRB- cord-354133-11b0d499 230 37 [ [ -LRB- cord-354133-11b0d499 230 38 43 43 CD cord-354133-11b0d499 230 39 ] ] -RRB- cord-354133-11b0d499 230 40 [ [ -LRB- cord-354133-11b0d499 230 41 44 44 CD cord-354133-11b0d499 230 42 ] ] -RRB- cord-354133-11b0d499 230 43 [ [ -LRB- cord-354133-11b0d499 230 44 45 45 CD cord-354133-11b0d499 230 45 ] ] -RRB- cord-354133-11b0d499 230 46 [ [ -LRB- cord-354133-11b0d499 230 47 46 46 CD cord-354133-11b0d499 230 48 ] ] -RRB- cord-354133-11b0d499 230 49 , , , cord-354133-11b0d499 230 50 which which WDT cord-354133-11b0d499 230 51 can can MD cord-354133-11b0d499 230 52 be be VB cord-354133-11b0d499 230 53 utilised utilise VBN cord-354133-11b0d499 230 54 along along IN cord-354133-11b0d499 230 55 with with IN cord-354133-11b0d499 230 56 excess excess JJ cord-354133-11b0d499 230 57 death death NN cord-354133-11b0d499 230 58 data datum NNS cord-354133-11b0d499 230 59 [ [ -LRB- cord-354133-11b0d499 230 60 35 35 CD cord-354133-11b0d499 230 61 ] ] -RRB- cord-354133-11b0d499 230 62 to to TO cord-354133-11b0d499 230 63 estimate estimate VB cord-354133-11b0d499 230 64 the the DT cord-354133-11b0d499 230 65 infection infection NN cord-354133-11b0d499 230 66 fatality fatality NN cord-354133-11b0d499 230 67 ratio ratio NN cord-354133-11b0d499 230 68 . . . cord-354133-11b0d499 231 1 These these DT cord-354133-11b0d499 231 2 IFR IFR NNP cord-354133-11b0d499 231 3 values value NNS cord-354133-11b0d499 231 4 are be VBP cord-354133-11b0d499 231 5 shown show VBN cord-354133-11b0d499 231 6 in in IN cord-354133-11b0d499 231 7 Table Table NNP cord-354133-11b0d499 231 8 2 2 CD cord-354133-11b0d499 231 9 along along IN cord-354133-11b0d499 231 10 with with IN cord-354133-11b0d499 231 11 the the DT cord-354133-11b0d499 231 12 correction correction NN cord-354133-11b0d499 231 13 factors factor NNS cord-354133-11b0d499 231 14 used use VBN cord-354133-11b0d499 231 15 . . . cord-354133-11b0d499 232 1 Some some DT cord-354133-11b0d499 232 2 of of IN cord-354133-11b0d499 232 3 the the DT cord-354133-11b0d499 232 4 seroprevalence seroprevalence NN cord-354133-11b0d499 232 5 data data NN cord-354133-11b0d499 232 6 is be VBZ cord-354133-11b0d499 232 7 preliminary preliminary JJ cord-354133-11b0d499 232 8 , , , cord-354133-11b0d499 232 9 including include VBG cord-354133-11b0d499 232 10 studies study NNS cord-354133-11b0d499 232 11 of of IN cord-354133-11b0d499 232 12 Germany Germany NNP cord-354133-11b0d499 232 13 , , , cord-354133-11b0d499 232 14 Sweden Sweden NNP cord-354133-11b0d499 232 15 and and CC cord-354133-11b0d499 232 16 Italy Italy NNP cord-354133-11b0d499 232 17 , , , cord-354133-11b0d499 232 18 and and CC cord-354133-11b0d499 232 19 others other NNS cord-354133-11b0d499 232 20 are be VBP cord-354133-11b0d499 232 21 for for IN cord-354133-11b0d499 232 22 specific specific JJ cord-354133-11b0d499 232 23 regions region NNS cord-354133-11b0d499 232 24 of of IN cord-354133-11b0d499 232 25 the the DT cord-354133-11b0d499 232 26 country country NN cord-354133-11b0d499 232 27 and and CC cord-354133-11b0d499 232 28 may may MD cord-354133-11b0d499 232 29 not not RB cord-354133-11b0d499 232 30 be be VB cord-354133-11b0d499 232 31 representative representative JJ cord-354133-11b0d499 232 32 . . . cord-354133-11b0d499 233 1 Nonetheless nonetheless RB cord-354133-11b0d499 233 2 , , , cord-354133-11b0d499 233 3 the the DT cord-354133-11b0d499 233 4 estimated estimate VBN cord-354133-11b0d499 233 5 IFR IFR NNP cord-354133-11b0d499 233 6 values value NNS cord-354133-11b0d499 233 7 are be VBP cord-354133-11b0d499 233 8 reasonable reasonable JJ cord-354133-11b0d499 233 9 : : : cord-354133-11b0d499 233 10 Switzerland Switzerland NNP cord-354133-11b0d499 233 11 and and CC cord-354133-11b0d499 233 12 Germany Germany NNP cord-354133-11b0d499 233 13 are be VBP cord-354133-11b0d499 233 14 around around RB cord-354133-11b0d499 233 15 0.6 0.6 CD cord-354133-11b0d499 233 16 % % NN cord-354133-11b0d499 233 17 , , , cord-354133-11b0d499 233 18 above above IN cord-354133-11b0d499 233 19 Australia Australia NNP cord-354133-11b0d499 233 20 and and CC cord-354133-11b0d499 233 21 below below IN cord-354133-11b0d499 233 22 Sweden Sweden NNP cord-354133-11b0d499 233 23 and and CC cord-354133-11b0d499 233 24 USA USA NNP cord-354133-11b0d499 233 25 at at IN cord-354133-11b0d499 233 26 around around RB cord-354133-11b0d499 233 27 0.8 0.8 CD cord-354133-11b0d499 233 28 % % NN cord-354133-11b0d499 233 29 ; ; : cord-354133-11b0d499 233 30 Belgium Belgium NNP cord-354133-11b0d499 233 31 , , , cord-354133-11b0d499 233 32 UK UK NNP cord-354133-11b0d499 233 33 and and CC cord-354133-11b0d499 233 34 Spain Spain NNP cord-354133-11b0d499 233 35 are be VBP cord-354133-11b0d499 233 36 between between IN cord-354133-11b0d499 233 37 one one CD cord-354133-11b0d499 233 38 and and CC cord-354133-11b0d499 233 39 two two CD cord-354133-11b0d499 233 40 percent percent NN cord-354133-11b0d499 233 41 ; ; : cord-354133-11b0d499 233 42 and and CC cord-354133-11b0d499 233 43 Italy Italy NNP cord-354133-11b0d499 233 44 higher higher RBR cord-354133-11b0d499 233 45 at at IN cord-354133-11b0d499 233 46 around around IN cord-354133-11b0d499 233 47 3 3 CD cord-354133-11b0d499 233 48 % % NN cord-354133-11b0d499 233 49 . . . cord-354133-11b0d499 234 1 Ioannidis Ioannidis NNP cord-354133-11b0d499 234 2 [ [ -LRB- cord-354133-11b0d499 234 3 26 26 CD cord-354133-11b0d499 234 4 ] ] -RRB- cord-354133-11b0d499 234 5 also also RB cord-354133-11b0d499 234 6 calculated calculate VBD cord-354133-11b0d499 234 7 the the DT cord-354133-11b0d499 234 8 IFR IFR NNP cord-354133-11b0d499 234 9 for for IN cord-354133-11b0d499 234 10 many many JJ cord-354133-11b0d499 234 11 of of IN cord-354133-11b0d499 234 12 these these DT cord-354133-11b0d499 234 13 countries country NNS cord-354133-11b0d499 234 14 using use VBG cord-354133-11b0d499 234 15 seroprevalence seroprevalence NN cord-354133-11b0d499 234 16 studies study NNS cord-354133-11b0d499 234 17 , , , cord-354133-11b0d499 234 18 but but CC cord-354133-11b0d499 234 19 using use VBG cord-354133-11b0d499 234 20 only only RB cord-354133-11b0d499 234 21 single single JJ cord-354133-11b0d499 234 22 - - HYPH cord-354133-11b0d499 234 23 time time NN cord-354133-11b0d499 234 24 seroprevalence seroprevalence NN cord-354133-11b0d499 234 25 and and CC cord-354133-11b0d499 234 26 death death NN cord-354133-11b0d499 234 27 data datum NNS cord-354133-11b0d499 234 28 with with IN cord-354133-11b0d499 234 29 an an DT cord-354133-11b0d499 234 30 assumed assume VBN cord-354133-11b0d499 234 31 delay delay NN cord-354133-11b0d499 234 32 time time NN cord-354133-11b0d499 234 33 ( ( -LRB- cord-354133-11b0d499 234 34 generally generally RB cord-354133-11b0d499 234 35 a a DT cord-354133-11b0d499 234 36 week week NN cord-354133-11b0d499 234 37 after after IN cord-354133-11b0d499 234 38 the the DT cord-354133-11b0d499 234 39 midpoint midpoint NN cord-354133-11b0d499 234 40 of of IN cord-354133-11b0d499 234 41 the the DT cord-354133-11b0d499 234 42 seroprevalence seroprevalence NN cord-354133-11b0d499 234 43 survey survey NN cord-354133-11b0d499 234 44 ) ) -RRB- cord-354133-11b0d499 234 45 ; ; : cord-354133-11b0d499 234 46 these these DT cord-354133-11b0d499 234 47 are be VBP cord-354133-11b0d499 234 48 also also RB cord-354133-11b0d499 234 49 shown show VBN cord-354133-11b0d499 234 50 in in IN cord-354133-11b0d499 234 51 Table Table NNP cord-354133-11b0d499 234 52 2 2 CD cord-354133-11b0d499 234 53 and and CC cord-354133-11b0d499 234 54 are be VBP cord-354133-11b0d499 234 55 broadly broadly RB cord-354133-11b0d499 234 56 consistent consistent JJ cord-354133-11b0d499 234 57 with with IN cord-354133-11b0d499 234 58 our -PRON- PRP$ cord-354133-11b0d499 234 59 values value NNS cord-354133-11b0d499 234 60 except except IN cord-354133-11b0d499 234 61 where where WRB cord-354133-11b0d499 234 62 excess excess JJ cord-354133-11b0d499 234 63 deaths death NNS cord-354133-11b0d499 234 64 are be VBP cord-354133-11b0d499 234 65 significant significant JJ cord-354133-11b0d499 234 66 ( ( -LRB- cord-354133-11b0d499 234 67 e.g. e.g. RB cord-354133-11b0d499 234 68 Spain Spain NNP cord-354133-11b0d499 234 69 ) ) -RRB- cord-354133-11b0d499 234 70 . . . cord-354133-11b0d499 235 1 Our -PRON- PRP$ cord-354133-11b0d499 235 2 value value NN cord-354133-11b0d499 235 3 for for IN cord-354133-11b0d499 235 4 Germany Germany NNP cord-354133-11b0d499 235 5 is be VBZ cord-354133-11b0d499 235 6 somewhat somewhat RB cord-354133-11b0d499 235 7 higher high JJR cord-354133-11b0d499 235 8 but but CC cord-354133-11b0d499 235 9 we -PRON- PRP cord-354133-11b0d499 235 10 expect expect VBP cord-354133-11b0d499 235 11 that that IN cord-354133-11b0d499 235 12 it -PRON- PRP cord-354133-11b0d499 235 13 is be VBZ cord-354133-11b0d499 235 14 more more RBR cord-354133-11b0d499 235 15 reliable reliable JJ cord-354133-11b0d499 235 16 , , , cord-354133-11b0d499 235 17 using use VBG cord-354133-11b0d499 235 18 the the DT cord-354133-11b0d499 235 19 scaling scale VBG cord-354133-11b0d499 235 20 factor factor NN cord-354133-11b0d499 235 21 for for IN cord-354133-11b0d499 235 22 cases case NNS cord-354133-11b0d499 235 23 [ [ -LRB- cord-354133-11b0d499 235 24 38 38 CD cord-354133-11b0d499 235 25 ] ] -RRB- cord-354133-11b0d499 235 26 with with IN cord-354133-11b0d499 235 27 our -PRON- PRP$ cord-354133-11b0d499 235 28 calculated calculate VBN cord-354133-11b0d499 235 29 CFR CFR NNP cord-354133-11b0d499 235 30 rather rather RB cord-354133-11b0d499 235 31 than than IN cord-354133-11b0d499 235 32 the the DT cord-354133-11b0d499 235 33 absolute absolute JJ cord-354133-11b0d499 235 34 number number NN cord-354133-11b0d499 235 35 of of IN cord-354133-11b0d499 235 36 deaths death NNS cord-354133-11b0d499 235 37 at at IN cord-354133-11b0d499 235 38 a a DT cord-354133-11b0d499 235 39 certain certain JJ cord-354133-11b0d499 235 40 date date NN cord-354133-11b0d499 235 41 in in IN cord-354133-11b0d499 235 42 the the DT cord-354133-11b0d499 235 43 German german JJ cord-354133-11b0d499 235 44 town town NN cord-354133-11b0d499 235 45 of of IN cord-354133-11b0d499 235 46 Gangelt Gangelt NNP cord-354133-11b0d499 235 47 [ [ -LRB- cord-354133-11b0d499 235 48 26 26 CD cord-354133-11b0d499 235 49 ] ] -RRB- cord-354133-11b0d499 235 50 , , , cord-354133-11b0d499 235 51 which which WDT cord-354133-11b0d499 235 52 is be VBZ cord-354133-11b0d499 235 53 very very RB cord-354133-11b0d499 235 54 low low JJ cord-354133-11b0d499 235 55 and and CC cord-354133-11b0d499 235 56 reflects reflect VBZ cord-354133-11b0d499 235 57 a a DT cord-354133-11b0d499 235 58 date date NN cord-354133-11b0d499 235 59 early early RB cord-354133-11b0d499 235 60 in in IN cord-354133-11b0d499 235 61 the the DT cord-354133-11b0d499 235 62 German german JJ cord-354133-11b0d499 235 63 outbreak outbreak NN cord-354133-11b0d499 235 64 . . . cord-354133-11b0d499 236 1 Although although IN cord-354133-11b0d499 236 2 the the DT cord-354133-11b0d499 236 3 calculated calculate VBN cord-354133-11b0d499 236 4 IFR IFR NNP cord-354133-11b0d499 236 5 values value NNS cord-354133-11b0d499 236 6 are be VBP cord-354133-11b0d499 236 7 only only RB cord-354133-11b0d499 236 8 approximate approximate JJ cord-354133-11b0d499 236 9 and and CC cord-354133-11b0d499 236 10 subject subject JJ cord-354133-11b0d499 236 11 to to IN cord-354133-11b0d499 236 12 revision revision NN cord-354133-11b0d499 236 13 , , , cord-354133-11b0d499 236 14 it -PRON- PRP cord-354133-11b0d499 236 15 is be VBZ cord-354133-11b0d499 236 16 conceivable conceivable JJ cord-354133-11b0d499 236 17 that that IN cord-354133-11b0d499 236 18 higher high JJR cord-354133-11b0d499 236 19 IFR IFR NNP cord-354133-11b0d499 236 20 values value NNS cord-354133-11b0d499 236 21 may may MD cord-354133-11b0d499 236 22 reflect reflect VB cord-354133-11b0d499 236 23 higher high JJR cord-354133-11b0d499 236 24 fatality fatality NN cord-354133-11b0d499 236 25 ratios ratio NNS cord-354133-11b0d499 236 26 in in IN cord-354133-11b0d499 236 27 particular particular JJ cord-354133-11b0d499 236 28 places place NNS cord-354133-11b0d499 236 29 at at IN cord-354133-11b0d499 236 30 particular particular JJ cord-354133-11b0d499 236 31 times time NNS cord-354133-11b0d499 236 32 , , , cord-354133-11b0d499 236 33 due due IN cord-354133-11b0d499 236 34 to to IN cord-354133-11b0d499 236 35 overwhelmed overwhelmed JJ cord-354133-11b0d499 236 36 health health NN cord-354133-11b0d499 236 37 systems system NNS cord-354133-11b0d499 236 38 in in IN cord-354133-11b0d499 236 39 hard hard RB cord-354133-11b0d499 236 40 - - HYPH cord-354133-11b0d499 236 41 hit hit VBN cord-354133-11b0d499 236 42 areas area NNS cord-354133-11b0d499 236 43 or or CC cord-354133-11b0d499 236 44 specific specific JJ cord-354133-11b0d499 236 45 demographics demographic NNS cord-354133-11b0d499 236 46 or or CC cord-354133-11b0d499 236 47 baseline baseline JJ cord-354133-11b0d499 236 48 health health NN cord-354133-11b0d499 236 49 of of IN cord-354133-11b0d499 236 50 affected affected JJ cord-354133-11b0d499 236 51 populations population NNS cord-354133-11b0d499 236 52 . . . cord-354133-11b0d499 237 1 For for IN cord-354133-11b0d499 237 2 example example NN cord-354133-11b0d499 237 3 , , , cord-354133-11b0d499 237 4 it -PRON- PRP cord-354133-11b0d499 237 5 is be VBZ cord-354133-11b0d499 237 6 reasonable reasonable JJ cord-354133-11b0d499 237 7 to to TO cord-354133-11b0d499 237 8 conclude conclude VB cord-354133-11b0d499 237 9 that that IN cord-354133-11b0d499 237 10 in in IN cord-354133-11b0d499 237 11 Lombardy Lombardy NNP cord-354133-11b0d499 237 12 , , , cord-354133-11b0d499 237 13 Italy Italy NNP cord-354133-11b0d499 237 14 , , , cord-354133-11b0d499 237 15 the the DT cord-354133-11b0d499 237 16 older old JJR cord-354133-11b0d499 237 17 population population NN cord-354133-11b0d499 237 18 and and CC cord-354133-11b0d499 237 19 overwhelmed overwhelmed JJ cord-354133-11b0d499 237 20 health health NN cord-354133-11b0d499 237 21 system system NN cord-354133-11b0d499 237 22 caused cause VBD cord-354133-11b0d499 237 23 a a DT cord-354133-11b0d499 237 24 higher high JJR cord-354133-11b0d499 237 25 fatality fatality NN cord-354133-11b0d499 237 26 . . . cord-354133-11b0d499 238 1 CC CC NNP cord-354133-11b0d499 238 2 - - HYPH cord-354133-11b0d499 238 3 BY BY NNP cord-354133-11b0d499 238 4 - - HYPH cord-354133-11b0d499 238 5 NC NC NNP cord-354133-11b0d499 238 6 - - HYPH cord-354133-11b0d499 238 7 ND ND NNP cord-354133-11b0d499 238 8 4.0 4.0 CD cord-354133-11b0d499 238 9 International international JJ cord-354133-11b0d499 238 10 license license NN cord-354133-11b0d499 238 11 It -PRON- PRP cord-354133-11b0d499 238 12 is be VBZ cord-354133-11b0d499 238 13 made make VBN cord-354133-11b0d499 238 14 available available JJ cord-354133-11b0d499 238 15 under under IN cord-354133-11b0d499 238 16 a a DT cord-354133-11b0d499 238 17 perpetuity perpetuity NN cord-354133-11b0d499 238 18 . . . cord-354133-11b0d499 239 1 is be VBZ cord-354133-11b0d499 239 2 the the DT cord-354133-11b0d499 239 3 author author NN cord-354133-11b0d499 239 4 / / SYM cord-354133-11b0d499 239 5 funder funder NN cord-354133-11b0d499 239 6 , , , cord-354133-11b0d499 239 7 who who WP cord-354133-11b0d499 239 8 has have VBZ cord-354133-11b0d499 239 9 granted grant VBN cord-354133-11b0d499 239 10 medRxiv medRxiv NNS cord-354133-11b0d499 239 11 a a DT cord-354133-11b0d499 239 12 license license NN cord-354133-11b0d499 239 13 to to TO cord-354133-11b0d499 239 14 display display VB cord-354133-11b0d499 239 15 the the DT cord-354133-11b0d499 239 16 preprint preprint NN cord-354133-11b0d499 239 17 in in IN cord-354133-11b0d499 239 18 ( ( -LRB- cord-354133-11b0d499 239 19 which which WDT cord-354133-11b0d499 239 20 was be VBD cord-354133-11b0d499 239 21 not not RB cord-354133-11b0d499 239 22 certified certify VBN cord-354133-11b0d499 239 23 by by IN cord-354133-11b0d499 239 24 peer peer NN cord-354133-11b0d499 239 25 review review NN cord-354133-11b0d499 239 26 ) ) -RRB- cord-354133-11b0d499 240 1 preprint preprint NN cord-354133-11b0d499 240 2 ratio ratio NN cord-354133-11b0d499 240 3 compared compare VBN cord-354133-11b0d499 240 4 to to IN cord-354133-11b0d499 240 5 other other JJ cord-354133-11b0d499 240 6 places place NNS cord-354133-11b0d499 240 7 . . . cord-354133-11b0d499 241 1 In in IN cord-354133-11b0d499 241 2 fact fact NN cord-354133-11b0d499 241 3 , , , cord-354133-11b0d499 241 4 the the DT cord-354133-11b0d499 241 5 difference difference NN cord-354133-11b0d499 241 6 in in IN cord-354133-11b0d499 241 7 age age NN cord-354133-11b0d499 241 8 distribution distribution NN cord-354133-11b0d499 241 9 of of IN cord-354133-11b0d499 241 10 cases case NNS cord-354133-11b0d499 241 11 between between IN cord-354133-11b0d499 241 12 Italy Italy NNP cord-354133-11b0d499 241 13 and and CC cord-354133-11b0d499 241 14 Australia Australia NNP cord-354133-11b0d499 241 15 up up RP cord-354133-11b0d499 241 16 to to IN cord-354133-11b0d499 241 17 the the DT cord-354133-11b0d499 241 18 end end NN cord-354133-11b0d499 241 19 of of IN cord-354133-11b0d499 241 20 May May NNP cord-354133-11b0d499 241 21 ( ( -LRB- cord-354133-11b0d499 241 22 using use VBG cord-354133-11b0d499 241 23 data datum NNS cord-354133-11b0d499 241 24 from from IN cord-354133-11b0d499 241 25 [ [ -LRB- cord-354133-11b0d499 241 26 47 47 CD cord-354133-11b0d499 241 27 ] ] -RRB- cord-354133-11b0d499 241 28 and and CC cord-354133-11b0d499 241 29 [ [ -LRB- cord-354133-11b0d499 241 30 48 48 CD cord-354133-11b0d499 241 31 ] ] -RRB- cord-354133-11b0d499 241 32 ) ) -RRB- cord-354133-11b0d499 242 1 can can MD cord-354133-11b0d499 242 2 alone alone RB cord-354133-11b0d499 242 3 account account VB cord-354133-11b0d499 242 4 for for IN cord-354133-11b0d499 242 5 a a DT cord-354133-11b0d499 242 6 factor factor NN cord-354133-11b0d499 242 7 of of IN cord-354133-11b0d499 242 8 three three CD cord-354133-11b0d499 242 9 in in IN cord-354133-11b0d499 242 10 the the DT cord-354133-11b0d499 242 11 IFR IFR NNP cord-354133-11b0d499 242 12 . . . cord-354133-11b0d499 243 1 Therefore therefore RB cord-354133-11b0d499 243 2 , , , cord-354133-11b0d499 243 3 while while IN cord-354133-11b0d499 243 4 differences difference NNS cord-354133-11b0d499 243 5 in in IN cord-354133-11b0d499 243 6 testing testing NN cord-354133-11b0d499 243 7 and and CC cord-354133-11b0d499 243 8 reporting reporting NN cord-354133-11b0d499 243 9 between between IN cord-354133-11b0d499 243 10 different different JJ cord-354133-11b0d499 243 11 countries country NNS cord-354133-11b0d499 243 12 undoubtedly undoubtedly RB cord-354133-11b0d499 243 13 account account VBP cord-354133-11b0d499 243 14 for for IN cord-354133-11b0d499 243 15 much much JJ cord-354133-11b0d499 243 16 of of IN cord-354133-11b0d499 243 17 the the DT cord-354133-11b0d499 243 18 variation variation NN cord-354133-11b0d499 243 19 in in IN cord-354133-11b0d499 243 20 IFR IFR NNP cord-354133-11b0d499 243 21 between between IN cord-354133-11b0d499 243 22 countries country NNS cord-354133-11b0d499 243 23 , , , cord-354133-11b0d499 243 24 we -PRON- PRP cord-354133-11b0d499 243 25 neither neither CC cord-354133-11b0d499 243 26 expect expect VBP cord-354133-11b0d499 243 27 nor nor CC cord-354133-11b0d499 243 28 find find VBP cord-354133-11b0d499 243 29 that that IN cord-354133-11b0d499 243 30 IFR IFR NNP cord-354133-11b0d499 243 31 is be VBZ cord-354133-11b0d499 243 32 the the DT cord-354133-11b0d499 243 33 same same JJ cord-354133-11b0d499 243 34 for for IN cord-354133-11b0d499 243 35 all all DT cord-354133-11b0d499 243 36 COVID-19 covid-19 CD cord-354133-11b0d499 243 37 outbreaks outbreak NNS cord-354133-11b0d499 243 38 . . . cord-354133-11b0d499 244 1 Country country NN cord-354133-11b0d499 244 2 - - HYPH cord-354133-11b0d499 244 3 specific specific JJ cord-354133-11b0d499 244 4 factors factor NNS cord-354133-11b0d499 244 5 that that WDT cord-354133-11b0d499 244 6 influence influence VBP cord-354133-11b0d499 244 7 IFR IFR NNP cord-354133-11b0d499 244 8 and and CC cord-354133-11b0d499 244 9 differ differ VBP cord-354133-11b0d499 244 10 between between IN cord-354133-11b0d499 244 11 countries country NNS cord-354133-11b0d499 244 12 include include VBP cord-354133-11b0d499 244 13 testing test VBG cord-354133-11b0d499 244 14 and and CC cord-354133-11b0d499 244 15 reporting reporting NN cord-354133-11b0d499 244 16 , , , cord-354133-11b0d499 244 17 age age NN cord-354133-11b0d499 244 18 demographics demographic NNS cord-354133-11b0d499 244 19 [ [ -LRB- cord-354133-11b0d499 244 20 49 49 CD cord-354133-11b0d499 244 21 ] ] -RRB- cord-354133-11b0d499 244 22 , , , cord-354133-11b0d499 244 23 health health NN cord-354133-11b0d499 244 24 - - HYPH cord-354133-11b0d499 244 25 care care NN cord-354133-11b0d499 244 26 systems system NNS cord-354133-11b0d499 244 27 and and CC cord-354133-11b0d499 244 28 treatments treatment NNS cord-354133-11b0d499 244 29 [ [ -LRB- cord-354133-11b0d499 244 30 32 32 CD cord-354133-11b0d499 244 31 ] ] -RRB- cord-354133-11b0d499 244 32 , , , cord-354133-11b0d499 244 33 mask mask NN cord-354133-11b0d499 244 34 - - HYPH cord-354133-11b0d499 244 35 wearing wear VBG cord-354133-11b0d499 244 36 and and CC cord-354133-11b0d499 244 37 other other JJ cord-354133-11b0d499 244 38 behaviours behaviour NNS cord-354133-11b0d499 244 39 , , , cord-354133-11b0d499 244 40 climate climate NN cord-354133-11b0d499 244 41 and and CC cord-354133-11b0d499 244 42 culture culture NN cord-354133-11b0d499 244 43 , , , cord-354133-11b0d499 244 44 transport transport NN cord-354133-11b0d499 244 45 infrastructure infrastructure NN cord-354133-11b0d499 244 46 and and CC cord-354133-11b0d499 244 47 community community NN cord-354133-11b0d499 244 48 mobility mobility NN cord-354133-11b0d499 244 49 [ [ -LRB- cord-354133-11b0d499 244 50 50 50 CD cord-354133-11b0d499 244 51 ] ] -RRB- cord-354133-11b0d499 244 52 , , , cord-354133-11b0d499 244 53 genetic genetic JJ cord-354133-11b0d499 244 54 factors factor NNS cord-354133-11b0d499 244 55 or or CC cord-354133-11b0d499 244 56 prevalence prevalence NN cord-354133-11b0d499 244 57 of of IN cord-354133-11b0d499 244 58 particular particular JJ cord-354133-11b0d499 244 59 antibodies antibody NNS cord-354133-11b0d499 244 60 that that WDT cord-354133-11b0d499 244 61 affect affect VBP cord-354133-11b0d499 244 62 immune immune JJ cord-354133-11b0d499 244 63 response response NN cord-354133-11b0d499 244 64 [ [ -LRB- cord-354133-11b0d499 244 65 51 51 CD cord-354133-11b0d499 244 66 ] ] -RRB- cord-354133-11b0d499 244 67 . . . cord-354133-11b0d499 245 1 There there EX cord-354133-11b0d499 245 2 is be VBZ cord-354133-11b0d499 245 3 some some DT cord-354133-11b0d499 245 4 evidence evidence NN cord-354133-11b0d499 245 5 that that IN cord-354133-11b0d499 245 6 the the DT cord-354133-11b0d499 245 7 IFR IFR NNP cord-354133-11b0d499 245 8 might may MD cord-354133-11b0d499 245 9 be be VB cord-354133-11b0d499 245 10 decreasing decrease VBG cord-354133-11b0d499 245 11 over over IN cord-354133-11b0d499 245 12 time time NN cord-354133-11b0d499 245 13 in in IN cord-354133-11b0d499 245 14 some some DT cord-354133-11b0d499 245 15 countries country NNS cord-354133-11b0d499 245 16 , , , cord-354133-11b0d499 245 17 especially especially RB cord-354133-11b0d499 245 18 those those DT cord-354133-11b0d499 245 19 experiencing experience VBG cord-354133-11b0d499 245 20 a a DT cord-354133-11b0d499 245 21 " " `` cord-354133-11b0d499 245 22 second second JJ cord-354133-11b0d499 245 23 wave wave NN cord-354133-11b0d499 245 24 " " '' cord-354133-11b0d499 245 25 . . . cord-354133-11b0d499 246 1 This this DT cord-354133-11b0d499 246 2 is be VBZ cord-354133-11b0d499 246 3 observed observe VBN cord-354133-11b0d499 246 4 , , , cord-354133-11b0d499 246 5 for for IN cord-354133-11b0d499 246 6 example example NN cord-354133-11b0d499 246 7 , , , cord-354133-11b0d499 246 8 in in IN cord-354133-11b0d499 246 9 the the DT cord-354133-11b0d499 246 10 data datum NNS cord-354133-11b0d499 246 11 for for IN cord-354133-11b0d499 246 12 the the DT cord-354133-11b0d499 246 13 USA USA NNP cord-354133-11b0d499 246 14 in in IN cord-354133-11b0d499 246 15 Figure Figure NNP cord-354133-11b0d499 246 16 7 7 CD cord-354133-11b0d499 246 17 , , , cord-354133-11b0d499 246 18 demonstrated demonstrate VBN cord-354133-11b0d499 246 19 in in IN cord-354133-11b0d499 246 20 the the DT cord-354133-11b0d499 246 21 increasing increase VBG cord-354133-11b0d499 246 22 mismatch mismatch NN cord-354133-11b0d499 246 23 in in IN cord-354133-11b0d499 246 24 case case NN cord-354133-11b0d499 246 25 and and CC cord-354133-11b0d499 246 26 death death NN cord-354133-11b0d499 246 27 distributions distribution NNS cord-354133-11b0d499 246 28 . . . cord-354133-11b0d499 247 1 CC CC NNP cord-354133-11b0d499 247 2 - - HYPH cord-354133-11b0d499 247 3 BY BY NNP cord-354133-11b0d499 247 4 - - HYPH cord-354133-11b0d499 247 5 NC NC NNP cord-354133-11b0d499 247 6 - - HYPH cord-354133-11b0d499 247 7 ND ND NNP cord-354133-11b0d499 247 8 4.0 4.0 CD cord-354133-11b0d499 247 9 International international JJ cord-354133-11b0d499 247 10 license license NN cord-354133-11b0d499 247 11 It -PRON- PRP cord-354133-11b0d499 247 12 is be VBZ cord-354133-11b0d499 247 13 made make VBN cord-354133-11b0d499 247 14 available available JJ cord-354133-11b0d499 247 15 under under IN cord-354133-11b0d499 247 16 a a DT cord-354133-11b0d499 247 17 perpetuity perpetuity NN cord-354133-11b0d499 247 18 . . . cord-354133-11b0d499 248 1 is be VBZ cord-354133-11b0d499 248 2 the the DT cord-354133-11b0d499 248 3 author author NN cord-354133-11b0d499 248 4 / / SYM cord-354133-11b0d499 248 5 funder funder NN cord-354133-11b0d499 248 6 , , , cord-354133-11b0d499 248 7 who who WP cord-354133-11b0d499 248 8 has have VBZ cord-354133-11b0d499 248 9 granted grant VBN cord-354133-11b0d499 248 10 medRxiv medRxiv NNS cord-354133-11b0d499 248 11 a a DT cord-354133-11b0d499 248 12 license license NN cord-354133-11b0d499 248 13 to to TO cord-354133-11b0d499 248 14 display display VB cord-354133-11b0d499 248 15 the the DT cord-354133-11b0d499 248 16 preprint preprint NN cord-354133-11b0d499 248 17 in in IN cord-354133-11b0d499 248 18 ( ( -LRB- cord-354133-11b0d499 248 19 which which WDT cord-354133-11b0d499 248 20 was be VBD cord-354133-11b0d499 248 21 not not RB cord-354133-11b0d499 248 22 certified certify VBN cord-354133-11b0d499 248 23 by by IN cord-354133-11b0d499 248 24 peer peer NN cord-354133-11b0d499 248 25 review review NN cord-354133-11b0d499 248 26 ) ) -RRB- cord-354133-11b0d499 248 27 preprint preprint NN cord-354133-11b0d499 249 1 The the DT cord-354133-11b0d499 249 2 copyright copyright NN cord-354133-11b0d499 249 3 holder holder NN cord-354133-11b0d499 249 4 for for IN cord-354133-11b0d499 249 5 this this DT cord-354133-11b0d499 249 6 this this DT cord-354133-11b0d499 249 7 version version NN cord-354133-11b0d499 249 8 posted post VBD cord-354133-11b0d499 249 9 October October NNP cord-354133-11b0d499 249 10 27 27 CD cord-354133-11b0d499 249 11 , , , cord-354133-11b0d499 249 12 2020 2020 CD cord-354133-11b0d499 249 13 . . . cord-354133-11b0d499 250 1 ; ; : cord-354133-11b0d499 250 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 250 3 doi doi NN cord-354133-11b0d499 250 4 : : : cord-354133-11b0d499 251 1 medRxiv medRxiv NNS cord-354133-11b0d499 251 2 preprint preprint NN cord-354133-11b0d499 251 3 25 25 CD cord-354133-11b0d499 251 4 later later RB cord-354133-11b0d499 251 5 in in IN cord-354133-11b0d499 251 6 the the DT cord-354133-11b0d499 251 7 outbreak outbreak NN cord-354133-11b0d499 251 8 . . . cord-354133-11b0d499 252 1 We -PRON- PRP cord-354133-11b0d499 252 2 can can MD cord-354133-11b0d499 252 3 use use VB cord-354133-11b0d499 252 4 the the DT cord-354133-11b0d499 252 5 TSD TSD NNP cord-354133-11b0d499 252 6 analysis analysis NN cord-354133-11b0d499 252 7 to to TO cord-354133-11b0d499 252 8 analyse analyse VB cord-354133-11b0d499 252 9 the the DT cord-354133-11b0d499 252 10 latter latter JJ cord-354133-11b0d499 252 11 part part NN cord-354133-11b0d499 252 12 of of IN cord-354133-11b0d499 252 13 the the DT cord-354133-11b0d499 252 14 outbreak outbreak NN cord-354133-11b0d499 252 15 ( ( -LRB- cord-354133-11b0d499 252 16 from from IN cord-354133-11b0d499 252 17 July July NNP cord-354133-11b0d499 252 18 to to IN cord-354133-11b0d499 252 19 September September NNP cord-354133-11b0d499 252 20 ) ) -RRB- cord-354133-11b0d499 252 21 , , , cord-354133-11b0d499 252 22 giving give VBG cord-354133-11b0d499 252 23 a a DT cord-354133-11b0d499 252 24 CFR CFR NNP cord-354133-11b0d499 252 25 of of IN cord-354133-11b0d499 252 26 1.5 1.5 CD cord-354133-11b0d499 252 27 - - SYM cord-354133-11b0d499 252 28 1.7 1.7 CD cord-354133-11b0d499 252 29 % % NN cord-354133-11b0d499 252 30 and and CC cord-354133-11b0d499 252 31 a a DT cord-354133-11b0d499 252 32 delay delay NN cord-354133-11b0d499 252 33 time time NN cord-354133-11b0d499 252 34 of of IN cord-354133-11b0d499 252 35 2 2 CD cord-354133-11b0d499 252 36 - - SYM cord-354133-11b0d499 252 37 3 3 CD cord-354133-11b0d499 252 38 weeks week NNS cord-354133-11b0d499 252 39 . . . cord-354133-11b0d499 253 1 Similar similar JJ cord-354133-11b0d499 253 2 analyses analysis NNS cord-354133-11b0d499 253 3 for for IN cord-354133-11b0d499 253 4 individual individual JJ cord-354133-11b0d499 253 5 states state NNS cord-354133-11b0d499 253 6 of of IN cord-354133-11b0d499 253 7 the the DT cord-354133-11b0d499 253 8 USA USA NNP cord-354133-11b0d499 253 9 give give VBP cord-354133-11b0d499 253 10 stable stable JJ cord-354133-11b0d499 253 11 CFR CFR NNP cord-354133-11b0d499 253 12 values value NNS cord-354133-11b0d499 253 13 from from IN cord-354133-11b0d499 253 14 1.1 1.1 CD cord-354133-11b0d499 253 15 - - SYM cord-354133-11b0d499 253 16 2.3 2.3 CD cord-354133-11b0d499 253 17 % % NN cord-354133-11b0d499 253 18 with with IN cord-354133-11b0d499 253 19 delay delay NN cord-354133-11b0d499 253 20 times time NNS cord-354133-11b0d499 253 21 between between IN cord-354133-11b0d499 253 22 four four CD cord-354133-11b0d499 253 23 and and CC cord-354133-11b0d499 253 24 24 24 CD cord-354133-11b0d499 253 25 days day NNS cord-354133-11b0d499 253 26 , , , cord-354133-11b0d499 253 27 with with IN cord-354133-11b0d499 253 28 a a DT cord-354133-11b0d499 253 29 mean mean NN cord-354133-11b0d499 253 30 of of IN cord-354133-11b0d499 253 31 1.6 1.6 CD cord-354133-11b0d499 253 32 % % NN cord-354133-11b0d499 253 33 CFR CFR NNP cord-354133-11b0d499 253 34 and and CC cord-354133-11b0d499 253 35 17 17 CD cord-354133-11b0d499 253 36 days day NNS cord-354133-11b0d499 253 37 ' ' POS cord-354133-11b0d499 253 38 delay delay NN cord-354133-11b0d499 253 39 over over IN cord-354133-11b0d499 253 40 states state NNS cord-354133-11b0d499 253 41 with with IN cord-354133-11b0d499 253 42 robust robust JJ cord-354133-11b0d499 253 43 fits fit NNS cord-354133-11b0d499 253 44 . . . cord-354133-11b0d499 254 1 This this DT cord-354133-11b0d499 254 2 later later JJ cord-354133-11b0d499 254 3 CFR CFR NNP cord-354133-11b0d499 254 4 is be VBZ cord-354133-11b0d499 254 5 far far RB cord-354133-11b0d499 254 6 lower low JJR cord-354133-11b0d499 254 7 than than IN cord-354133-11b0d499 254 8 the the DT cord-354133-11b0d499 254 9 value value NN cord-354133-11b0d499 254 10 of of IN cord-354133-11b0d499 254 11 7 7 CD cord-354133-11b0d499 254 12 % % NN cord-354133-11b0d499 254 13 calculated calculate VBN cord-354133-11b0d499 254 14 early early RB cord-354133-11b0d499 254 15 in in IN cord-354133-11b0d499 254 16 the the DT cord-354133-11b0d499 254 17 outbreak outbreak NN cord-354133-11b0d499 254 18 . . . cord-354133-11b0d499 255 1 We -PRON- PRP cord-354133-11b0d499 255 2 observe observe VBP cord-354133-11b0d499 255 3 similar similar JJ cord-354133-11b0d499 255 4 effects effect NNS cord-354133-11b0d499 255 5 in in IN cord-354133-11b0d499 255 6 various various JJ cord-354133-11b0d499 255 7 other other JJ cord-354133-11b0d499 255 8 countries country NNS cord-354133-11b0d499 255 9 post post NN cord-354133-11b0d499 255 10 - - JJ cord-354133-11b0d499 255 11 July July NNP cord-354133-11b0d499 255 12 including include VBG cord-354133-11b0d499 255 13 Japan Japan NNP cord-354133-11b0d499 255 14 ( ( -LRB- cord-354133-11b0d499 255 15 reduced reduce VBN cord-354133-11b0d499 255 16 to to IN cord-354133-11b0d499 255 17 1.1 1.1 CD cord-354133-11b0d499 255 18 % % NN cord-354133-11b0d499 255 19 and and CC cord-354133-11b0d499 255 20 22 22 CD cord-354133-11b0d499 255 21 days day NNS cord-354133-11b0d499 255 22 ' ' POS cord-354133-11b0d499 255 23 delay delay NN cord-354133-11b0d499 255 24 ) ) -RRB- cord-354133-11b0d499 255 25 and and CC cord-354133-11b0d499 255 26 Spain Spain NNP cord-354133-11b0d499 255 27 , , , cord-354133-11b0d499 255 28 France France NNP cord-354133-11b0d499 255 29 and and CC cord-354133-11b0d499 255 30 Portugal Portugal NNP cord-354133-11b0d499 255 31 ( ( -LRB- cord-354133-11b0d499 255 32 all all DT cord-354133-11b0d499 255 33 reduced reduce VBN cord-354133-11b0d499 255 34 to to IN cord-354133-11b0d499 255 35 0.8 0.8 CD cord-354133-11b0d499 255 36 - - SYM cord-354133-11b0d499 255 37 1.3 1.3 CD cord-354133-11b0d499 255 38 % % NN cord-354133-11b0d499 255 39 , , , cord-354133-11b0d499 255 40 12 12 CD cord-354133-11b0d499 255 41 - - SYM cord-354133-11b0d499 255 42 29 29 CD cord-354133-11b0d499 255 43 days day NNS cord-354133-11b0d499 255 44 ' ' POS cord-354133-11b0d499 255 45 delay delay NN cord-354133-11b0d499 255 46 ) ) -RRB- cord-354133-11b0d499 255 47 . . . cord-354133-11b0d499 256 1 These these DT cord-354133-11b0d499 256 2 values value NNS cord-354133-11b0d499 256 3 are be VBP cord-354133-11b0d499 256 4 all all RB cord-354133-11b0d499 256 5 similar similar JJ cord-354133-11b0d499 256 6 and and CC cord-354133-11b0d499 256 7 may may MD cord-354133-11b0d499 256 8 reflect reflect VB cord-354133-11b0d499 256 9 a a DT cord-354133-11b0d499 256 10 reasonable reasonable JJ cord-354133-11b0d499 256 11 estimate estimate NN cord-354133-11b0d499 256 12 for for IN cord-354133-11b0d499 256 13 CFR CFR NNP cord-354133-11b0d499 256 14 when when WRB cord-354133-11b0d499 256 15 testing testing NN cord-354133-11b0d499 256 16 is be VBZ cord-354133-11b0d499 256 17 adequate adequate JJ cord-354133-11b0d499 256 18 ; ; : cord-354133-11b0d499 256 19 we -PRON- PRP cord-354133-11b0d499 256 20 would would MD cord-354133-11b0d499 256 21 still still RB cord-354133-11b0d499 256 22 expect expect VB cord-354133-11b0d499 256 23 the the DT cord-354133-11b0d499 256 24 IFR IFR NNP cord-354133-11b0d499 256 25 to to TO cord-354133-11b0d499 256 26 be be VB cord-354133-11b0d499 256 27 lower low JJR cord-354133-11b0d499 256 28 by by IN cord-354133-11b0d499 256 29 a a DT cord-354133-11b0d499 256 30 factor factor NN cord-354133-11b0d499 256 31 of of IN cord-354133-11b0d499 256 32 at at RB cord-354133-11b0d499 256 33 least least RBS cord-354133-11b0d499 256 34 two two CD cord-354133-11b0d499 256 35 due due JJ cord-354133-11b0d499 256 36 to to IN cord-354133-11b0d499 256 37 undiagnosed undiagnosed JJ cord-354133-11b0d499 256 38 and and CC cord-354133-11b0d499 256 39 asymptomatic asymptomatic JJ cord-354133-11b0d499 256 40 cases case NNS cord-354133-11b0d499 256 41 . . . cord-354133-11b0d499 257 1 A a DT cord-354133-11b0d499 257 2 decrease decrease NN cord-354133-11b0d499 257 3 in in IN cord-354133-11b0d499 257 4 CFR CFR NNP cord-354133-11b0d499 257 5 over over IN cord-354133-11b0d499 257 6 time time NN cord-354133-11b0d499 257 7 may may MD cord-354133-11b0d499 257 8 also also RB cord-354133-11b0d499 257 9 indicate indicate VB cord-354133-11b0d499 257 10 a a DT cord-354133-11b0d499 257 11 change change NN cord-354133-11b0d499 257 12 in in IN cord-354133-11b0d499 257 13 the the DT cord-354133-11b0d499 257 14 demographics demographic NNS cord-354133-11b0d499 257 15 of of IN cord-354133-11b0d499 257 16 the the DT cord-354133-11b0d499 257 17 case case NN cord-354133-11b0d499 257 18 load load NN cord-354133-11b0d499 257 19 or or CC cord-354133-11b0d499 257 20 improvements improvement NNS cord-354133-11b0d499 257 21 in in IN cord-354133-11b0d499 257 22 treatment treatment NN cord-354133-11b0d499 257 23 or or CC cord-354133-11b0d499 257 24 even even RB cord-354133-11b0d499 257 25 an an DT cord-354133-11b0d499 257 26 increasing increase VBG cord-354133-11b0d499 257 27 time time NN cord-354133-11b0d499 257 28 delay delay NN cord-354133-11b0d499 257 29 between between IN cord-354133-11b0d499 257 30 reported report VBN cord-354133-11b0d499 257 31 cases case NNS cord-354133-11b0d499 257 32 and and CC cord-354133-11b0d499 257 33 deaths death NNS cord-354133-11b0d499 257 34 , , , cord-354133-11b0d499 257 35 perhaps perhaps RB cord-354133-11b0d499 257 36 due due IN cord-354133-11b0d499 257 37 to to IN cord-354133-11b0d499 257 38 earlier early JJR cord-354133-11b0d499 257 39 diagnosis diagnosis NN cord-354133-11b0d499 257 40 . . . cord-354133-11b0d499 258 1 We -PRON- PRP cord-354133-11b0d499 258 2 also also RB cord-354133-11b0d499 258 3 find find VBP cord-354133-11b0d499 258 4 that that IN cord-354133-11b0d499 258 5 , , , cord-354133-11b0d499 258 6 in in IN cord-354133-11b0d499 258 7 countries country NNS cord-354133-11b0d499 258 8 where where WRB cord-354133-11b0d499 258 9 the the DT cord-354133-11b0d499 258 10 time time NN cord-354133-11b0d499 258 11 delay delay NN cord-354133-11b0d499 258 12 is be VBZ cord-354133-11b0d499 258 13 significant significant JJ cord-354133-11b0d499 258 14 , , , cord-354133-11b0d499 258 15 the the DT cord-354133-11b0d499 258 16 TSD TSD NNP cord-354133-11b0d499 258 17 analysis analysis NN cord-354133-11b0d499 258 18 can can MD cord-354133-11b0d499 258 19 serve serve VB cord-354133-11b0d499 258 20 in in IN cord-354133-11b0d499 258 21 a a DT cord-354133-11b0d499 258 22 predictive predictive JJ cord-354133-11b0d499 258 23 capacity capacity NN cord-354133-11b0d499 258 24 for for IN cord-354133-11b0d499 258 25 numbers number NNS cord-354133-11b0d499 258 26 of of IN cord-354133-11b0d499 258 27 deaths death NNS cord-354133-11b0d499 258 28 , , , cord-354133-11b0d499 258 29 using use VBG cord-354133-11b0d499 258 30 the the DT cord-354133-11b0d499 258 31 linear linear JJ cord-354133-11b0d499 258 32 relationship relationship NN cord-354133-11b0d499 258 33 between between IN cord-354133-11b0d499 258 34 deaths death NNS cord-354133-11b0d499 258 35 and and CC cord-354133-11b0d499 258 36 time time NN cord-354133-11b0d499 258 37 - - HYPH cord-354133-11b0d499 258 38 shifted shift VBN cord-354133-11b0d499 258 39 cases case NNS cord-354133-11b0d499 258 40 . . . cord-354133-11b0d499 259 1 Figure figure NN cord-354133-11b0d499 259 2 9 9 CD cord-354133-11b0d499 259 3 shows show NNS cord-354133-11b0d499 259 4 this this DT cord-354133-11b0d499 259 5 prediction prediction NN cord-354133-11b0d499 259 6 for for IN cord-354133-11b0d499 259 7 the the DT cord-354133-11b0d499 259 8 second second JJ cord-354133-11b0d499 259 9 phase phase NN cord-354133-11b0d499 259 10 of of IN cord-354133-11b0d499 259 11 the the DT cord-354133-11b0d499 259 12 COVID-19 covid-19 JJ cord-354133-11b0d499 259 13 outbreak outbreak NN cord-354133-11b0d499 259 14 in in IN cord-354133-11b0d499 259 15 France France NNP cord-354133-11b0d499 259 16 from from IN cord-354133-11b0d499 259 17 August August NNP cord-354133-11b0d499 259 18 . . . cord-354133-11b0d499 260 1 Using use VBG cord-354133-11b0d499 260 2 parameters parameter NNS cord-354133-11b0d499 260 3 calculated calculate VBN cord-354133-11b0d499 260 4 from from IN cord-354133-11b0d499 260 5 TSD TSD NNP cord-354133-11b0d499 260 6 analysis analysis NN cord-354133-11b0d499 260 7 for for IN cord-354133-11b0d499 260 8 August August NNP cord-354133-11b0d499 260 9 to to IN cord-354133-11b0d499 260 10 mid mid NNP cord-354133-11b0d499 260 11 - - NNP cord-354133-11b0d499 260 12 October October NNP cord-354133-11b0d499 260 13 , , , cord-354133-11b0d499 260 14 reported report VBD cord-354133-11b0d499 260 15 case case NN cord-354133-11b0d499 260 16 data datum NNS cord-354133-11b0d499 260 17 can can MD cord-354133-11b0d499 260 18 be be VB cord-354133-11b0d499 260 19 time time NN cord-354133-11b0d499 260 20 - - HYPH cord-354133-11b0d499 260 21 shifted shift VBN cord-354133-11b0d499 260 22 and and CC cord-354133-11b0d499 260 23 linearly linearly RB cord-354133-11b0d499 260 24 scaled scale VBN cord-354133-11b0d499 260 25 to to TO cord-354133-11b0d499 260 26 predict predict VB cord-354133-11b0d499 260 27 daily daily JJ cord-354133-11b0d499 260 28 deaths death NNS cord-354133-11b0d499 260 29 for for IN cord-354133-11b0d499 260 30 France France NNP cord-354133-11b0d499 260 31 for for IN cord-354133-11b0d499 260 32 the the DT cord-354133-11b0d499 260 33 next next JJ cord-354133-11b0d499 260 34 three three CD cord-354133-11b0d499 260 35 weeks week NNS cord-354133-11b0d499 260 36 . . . cord-354133-11b0d499 261 1 This this DT cord-354133-11b0d499 261 2 is be VBZ cord-354133-11b0d499 261 3 useful useful JJ cord-354133-11b0d499 261 4 for for IN cord-354133-11b0d499 261 5 public public JJ cord-354133-11b0d499 261 6 health health NN cord-354133-11b0d499 261 7 planning planning NN cord-354133-11b0d499 261 8 , , , cord-354133-11b0d499 261 9 as as RB cord-354133-11b0d499 261 10 well well RB cord-354133-11b0d499 261 11 as as IN cord-354133-11b0d499 261 12 decision decision NN cord-354133-11b0d499 261 13 - - HYPH cord-354133-11b0d499 261 14 making make VBG cord-354133-11b0d499 261 15 regarding regard VBG cord-354133-11b0d499 261 16 implementation implementation NN cord-354133-11b0d499 261 17 of of IN cord-354133-11b0d499 261 18 restrictions restriction NNS cord-354133-11b0d499 261 19 . . . cord-354133-11b0d499 262 1 The the DT cord-354133-11b0d499 262 2 time time NN cord-354133-11b0d499 262 3 - - HYPH cord-354133-11b0d499 262 4 shifted shift VBN cord-354133-11b0d499 262 5 distribution distribution NN cord-354133-11b0d499 262 6 analysis analysis NN cord-354133-11b0d499 262 7 is be VBZ cord-354133-11b0d499 262 8 a a DT cord-354133-11b0d499 262 9 straightforward straightforward JJ cord-354133-11b0d499 262 10 way way NN cord-354133-11b0d499 262 11 to to TO cord-354133-11b0d499 262 12 predict predict VB cord-354133-11b0d499 262 13 CFR CFR NNP cord-354133-11b0d499 262 14 over over IN cord-354133-11b0d499 262 15 time time NN cord-354133-11b0d499 262 16 , , , cord-354133-11b0d499 262 17 using use VBG cord-354133-11b0d499 262 18 only only RB cord-354133-11b0d499 262 19 publicly publicly RB cord-354133-11b0d499 262 20 available available JJ cord-354133-11b0d499 262 21 data datum NNS cord-354133-11b0d499 262 22 on on IN cord-354133-11b0d499 262 23 cases case NNS cord-354133-11b0d499 262 24 and and CC cord-354133-11b0d499 262 25 deaths death NNS cord-354133-11b0d499 262 26 and and CC cord-354133-11b0d499 262 27 requiring require VBG cord-354133-11b0d499 262 28 no no DT cord-354133-11b0d499 262 29 assumptions assumption NNS cord-354133-11b0d499 262 30 or or CC cord-354133-11b0d499 262 31 parametrisations parametrisation NNS cord-354133-11b0d499 262 32 regarding regard VBG cord-354133-11b0d499 262 33 the the DT cord-354133-11b0d499 262 34 progress progress NN cord-354133-11b0d499 262 35 of of IN cord-354133-11b0d499 262 36 the the DT cord-354133-11b0d499 262 37 illness illness NN cord-354133-11b0d499 262 38 . . . cord-354133-11b0d499 263 1 The the DT cord-354133-11b0d499 263 2 beauty beauty NN cord-354133-11b0d499 263 3 of of IN cord-354133-11b0d499 263 4 this this DT cord-354133-11b0d499 263 5 method method NN cord-354133-11b0d499 263 6 is be VBZ cord-354133-11b0d499 263 7 in in IN cord-354133-11b0d499 263 8 its -PRON- PRP$ cord-354133-11b0d499 263 9 transparency transparency NN cord-354133-11b0d499 263 10 and and CC cord-354133-11b0d499 263 11 simplicity simplicity NN cord-354133-11b0d499 263 12 ; ; : cord-354133-11b0d499 263 13 the the DT cord-354133-11b0d499 263 14 lack lack NN cord-354133-11b0d499 263 15 of of IN cord-354133-11b0d499 263 16 assumptions assumption NNS cord-354133-11b0d499 263 17 allows allow VBZ cord-354133-11b0d499 263 18 more more JJR cord-354133-11b0d499 263 19 to to TO cord-354133-11b0d499 263 20 be be VB cord-354133-11b0d499 263 21 gained gain VBN cord-354133-11b0d499 263 22 from from IN cord-354133-11b0d499 263 23 the the DT cord-354133-11b0d499 263 24 data datum NNS cord-354133-11b0d499 263 25 , , , cord-354133-11b0d499 263 26 is be VBZ cord-354133-11b0d499 263 27 the the DT cord-354133-11b0d499 263 28 author author NN cord-354133-11b0d499 263 29 / / SYM cord-354133-11b0d499 263 30 funder funder NN cord-354133-11b0d499 263 31 , , , cord-354133-11b0d499 263 32 who who WP cord-354133-11b0d499 263 33 has have VBZ cord-354133-11b0d499 263 34 granted grant VBN cord-354133-11b0d499 263 35 medRxiv medRxiv NNS cord-354133-11b0d499 263 36 a a DT cord-354133-11b0d499 263 37 license license NN cord-354133-11b0d499 263 38 to to TO cord-354133-11b0d499 263 39 display display VB cord-354133-11b0d499 263 40 the the DT cord-354133-11b0d499 263 41 preprint preprint NN cord-354133-11b0d499 263 42 in in IN cord-354133-11b0d499 263 43 ( ( -LRB- cord-354133-11b0d499 263 44 which which WDT cord-354133-11b0d499 263 45 was be VBD cord-354133-11b0d499 263 46 not not RB cord-354133-11b0d499 263 47 certified certify VBN cord-354133-11b0d499 263 48 by by IN cord-354133-11b0d499 263 49 peer peer NN cord-354133-11b0d499 263 50 review review NN cord-354133-11b0d499 263 51 ) ) -RRB- cord-354133-11b0d499 264 1 preprint preprint NN cord-354133-11b0d499 265 1 The the DT cord-354133-11b0d499 265 2 copyright copyright NN cord-354133-11b0d499 265 3 holder holder NN cord-354133-11b0d499 265 4 for for IN cord-354133-11b0d499 265 5 this this DT cord-354133-11b0d499 265 6 this this DT cord-354133-11b0d499 265 7 version version NN cord-354133-11b0d499 265 8 posted post VBD cord-354133-11b0d499 265 9 October October NNP cord-354133-11b0d499 265 10 27 27 CD cord-354133-11b0d499 265 11 , , , cord-354133-11b0d499 265 12 2020 2020 CD cord-354133-11b0d499 265 13 . . . cord-354133-11b0d499 266 1 ; ; : cord-354133-11b0d499 266 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 266 3 doi doi NN cord-354133-11b0d499 266 4 : : : cord-354133-11b0d499 267 1 medRxiv medRxiv NNS cord-354133-11b0d499 267 2 preprint preprint NN cord-354133-11b0d499 267 3 including include VBG cord-354133-11b0d499 267 4 trends trend NNS cord-354133-11b0d499 267 5 that that WDT cord-354133-11b0d499 267 6 may may MD cord-354133-11b0d499 267 7 be be VB cord-354133-11b0d499 267 8 unexpected unexpected JJ cord-354133-11b0d499 267 9 or or CC cord-354133-11b0d499 267 10 changing change VBG cord-354133-11b0d499 267 11 over over IN cord-354133-11b0d499 267 12 time time NN cord-354133-11b0d499 267 13 . . . cord-354133-11b0d499 268 1 This this DT cord-354133-11b0d499 268 2 analysis analysis NN cord-354133-11b0d499 268 3 method method NN cord-354133-11b0d499 268 4 has have VBZ cord-354133-11b0d499 268 5 particular particular JJ cord-354133-11b0d499 268 6 utility utility NN cord-354133-11b0d499 268 7 early early RB cord-354133-11b0d499 268 8 in in IN cord-354133-11b0d499 268 9 an an DT cord-354133-11b0d499 268 10 outbreak outbreak NN cord-354133-11b0d499 268 11 , , , cord-354133-11b0d499 268 12 once once IN cord-354133-11b0d499 268 13 sufficient sufficient JJ cord-354133-11b0d499 268 14 data datum NNS cord-354133-11b0d499 268 15 are be VBP cord-354133-11b0d499 268 16 available available JJ cord-354133-11b0d499 268 17 for for IN cord-354133-11b0d499 268 18 a a DT cord-354133-11b0d499 268 19 robust robust JJ cord-354133-11b0d499 268 20 fit fit NN cord-354133-11b0d499 268 21 ( ( -LRB- cord-354133-11b0d499 268 22 beyond beyond IN cord-354133-11b0d499 268 23 the the DT cord-354133-11b0d499 268 24 exponential exponential JJ cord-354133-11b0d499 268 25 growth growth NN cord-354133-11b0d499 268 26 phase phase NN cord-354133-11b0d499 268 27 ) ) -RRB- cord-354133-11b0d499 268 28 . . . cord-354133-11b0d499 269 1 Without without IN cord-354133-11b0d499 269 2 the the DT cord-354133-11b0d499 269 3 benefit benefit NN cord-354133-11b0d499 269 4 of of IN cord-354133-11b0d499 269 5 hindsight hindsight NN cord-354133-11b0d499 269 6 , , , cord-354133-11b0d499 269 7 the the DT cord-354133-11b0d499 269 8 TSD TSD NNP cord-354133-11b0d499 269 9 - - HYPH cord-354133-11b0d499 269 10 calculated calculate VBN cord-354133-11b0d499 269 11 values value NNS cord-354133-11b0d499 269 12 for for IN cord-354133-11b0d499 269 13 CFR CFR NNP cord-354133-11b0d499 269 14 and and CC cord-354133-11b0d499 269 15 time time NN cord-354133-11b0d499 269 16 delay delay NN cord-354133-11b0d499 269 17 between between IN cord-354133-11b0d499 269 18 cases case NNS cord-354133-11b0d499 269 19 and and CC cord-354133-11b0d499 269 20 deaths death NNS cord-354133-11b0d499 269 21 can can MD cord-354133-11b0d499 269 22 shed shed VB cord-354133-11b0d499 269 23 light light NN cord-354133-11b0d499 269 24 on on IN cord-354133-11b0d499 269 25 the the DT cord-354133-11b0d499 269 26 virulence virulence NN cord-354133-11b0d499 269 27 of of IN cord-354133-11b0d499 269 28 a a DT cord-354133-11b0d499 269 29 disease disease NN cord-354133-11b0d499 269 30 and and CC cord-354133-11b0d499 269 31 on on IN cord-354133-11b0d499 269 32 the the DT cord-354133-11b0d499 269 33 conditions condition NNS cord-354133-11b0d499 269 34 that that WDT cord-354133-11b0d499 269 35 a a DT cord-354133-11b0d499 269 36 particular particular JJ cord-354133-11b0d499 269 37 country country NN cord-354133-11b0d499 269 38 may may MD cord-354133-11b0d499 269 39 be be VB cord-354133-11b0d499 269 40 facing face VBG cord-354133-11b0d499 269 41 . . . cord-354133-11b0d499 270 1 Excess excess JJ cord-354133-11b0d499 270 2 death death NN cord-354133-11b0d499 270 3 data datum NNS cord-354133-11b0d499 270 4 ( ( -LRB- cord-354133-11b0d499 270 5 where where WRB cord-354133-11b0d499 270 6 available available JJ cord-354133-11b0d499 270 7 ) ) -RRB- cord-354133-11b0d499 270 8 may may MD cord-354133-11b0d499 270 9 be be VB cord-354133-11b0d499 270 10 used use VBN cord-354133-11b0d499 270 11 to to TO cord-354133-11b0d499 270 12 correct correct VB cord-354133-11b0d499 270 13 death death NN cord-354133-11b0d499 270 14 data datum NNS cord-354133-11b0d499 270 15 , , , cord-354133-11b0d499 270 16 while while IN cord-354133-11b0d499 270 17 positive positive JJ cord-354133-11b0d499 270 18 test test NN cord-354133-11b0d499 270 19 rates rate NNS cord-354133-11b0d499 270 20 and and CC cord-354133-11b0d499 270 21 other other JJ cord-354133-11b0d499 270 22 indicators indicator NNS cord-354133-11b0d499 270 23 or or CC cord-354133-11b0d499 270 24 models model NNS cord-354133-11b0d499 270 25 of of IN cord-354133-11b0d499 270 26 testing test VBG cord-354133-11b0d499 270 27 adequacy adequacy NN cord-354133-11b0d499 270 28 can can MD cord-354133-11b0d499 270 29 often often RB cord-354133-11b0d499 270 30 give give VB cord-354133-11b0d499 270 31 an an DT cord-354133-11b0d499 270 32 early early JJ cord-354133-11b0d499 270 33 rough rough JJ cord-354133-11b0d499 270 34 idea idea NN cord-354133-11b0d499 270 35 of of IN cord-354133-11b0d499 270 36 the the DT cord-354133-11b0d499 270 37 true true JJ cord-354133-11b0d499 270 38 prevalence prevalence NN cord-354133-11b0d499 270 39 relative relative JJ cord-354133-11b0d499 270 40 to to IN cord-354133-11b0d499 270 41 reported report VBN cord-354133-11b0d499 270 42 case case NN cord-354133-11b0d499 270 43 numbers number NNS cord-354133-11b0d499 270 44 . . . cord-354133-11b0d499 271 1 These these DT cord-354133-11b0d499 271 2 data datum NNS cord-354133-11b0d499 271 3 can can MD cord-354133-11b0d499 271 4 be be VB cord-354133-11b0d499 271 5 used use VBN cord-354133-11b0d499 271 6 to to TO cord-354133-11b0d499 271 7 interpret interpret VB cord-354133-11b0d499 271 8 the the DT cord-354133-11b0d499 271 9 CFR CFR NNP cord-354133-11b0d499 271 10 calculated calculate VBN cord-354133-11b0d499 271 11 using use VBG cord-354133-11b0d499 271 12 TSD TSD NNP cord-354133-11b0d499 271 13 analysis analysis NN cord-354133-11b0d499 271 14 early early RB cord-354133-11b0d499 271 15 in in IN cord-354133-11b0d499 271 16 an an DT cord-354133-11b0d499 271 17 outbreak outbreak NN cord-354133-11b0d499 271 18 , , , cord-354133-11b0d499 271 19 and and CC cord-354133-11b0d499 271 20 to to TO cord-354133-11b0d499 271 21 approximate approximate VB cord-354133-11b0d499 271 22 the the DT cord-354133-11b0d499 271 23 IFR IFR NNP cord-354133-11b0d499 271 24 . . . cord-354133-11b0d499 272 1 is be VBZ cord-354133-11b0d499 272 2 the the DT cord-354133-11b0d499 272 3 author author NN cord-354133-11b0d499 272 4 / / SYM cord-354133-11b0d499 272 5 funder funder NN cord-354133-11b0d499 272 6 , , , cord-354133-11b0d499 272 7 who who WP cord-354133-11b0d499 272 8 has have VBZ cord-354133-11b0d499 272 9 granted grant VBN cord-354133-11b0d499 272 10 medRxiv medRxiv NNS cord-354133-11b0d499 272 11 a a DT cord-354133-11b0d499 272 12 license license NN cord-354133-11b0d499 272 13 to to TO cord-354133-11b0d499 272 14 display display VB cord-354133-11b0d499 272 15 the the DT cord-354133-11b0d499 272 16 preprint preprint NN cord-354133-11b0d499 272 17 in in IN cord-354133-11b0d499 272 18 ( ( -LRB- cord-354133-11b0d499 272 19 which which WDT cord-354133-11b0d499 272 20 was be VBD cord-354133-11b0d499 272 21 not not RB cord-354133-11b0d499 272 22 certified certify VBN cord-354133-11b0d499 272 23 by by IN cord-354133-11b0d499 272 24 peer peer NN cord-354133-11b0d499 272 25 review review NN cord-354133-11b0d499 272 26 ) ) -RRB- cord-354133-11b0d499 272 27 preprint preprint NN cord-354133-11b0d499 273 1 The the DT cord-354133-11b0d499 273 2 copyright copyright NN cord-354133-11b0d499 273 3 holder holder NN cord-354133-11b0d499 273 4 for for IN cord-354133-11b0d499 273 5 this this DT cord-354133-11b0d499 273 6 this this DT cord-354133-11b0d499 273 7 version version NN cord-354133-11b0d499 273 8 posted post VBD cord-354133-11b0d499 273 9 October October NNP cord-354133-11b0d499 273 10 27 27 CD cord-354133-11b0d499 273 11 , , , cord-354133-11b0d499 273 12 2020 2020 CD cord-354133-11b0d499 273 13 . . . cord-354133-11b0d499 274 1 ; ; : cord-354133-11b0d499 274 2 https://doi.org/10.1101/2020 https://doi.org/10.1101/2020 NN cord-354133-11b0d499 274 3 . . . cord-354133-11b0d499 275 1 10.25.20216671 10.25.20216671 CD cord-354133-11b0d499 275 2 doi doi NN cord-354133-11b0d499 275 3 : : : cord-354133-11b0d499 276 1 medRxiv medRxiv NNP cord-354133-11b0d499 276 2 preprint preprint NNP cord-354133-11b0d499 277 1 Our -PRON- PRP$ cord-354133-11b0d499 277 2 estimates estimate NNS cord-354133-11b0d499 277 3 of of IN cord-354133-11b0d499 277 4 IFR IFR NNP cord-354133-11b0d499 277 5 range range NN cord-354133-11b0d499 277 6 from from IN cord-354133-11b0d499 277 7 0.3 0.3 CD cord-354133-11b0d499 277 8 - - SYM cord-354133-11b0d499 277 9 3 3 CD cord-354133-11b0d499 277 10 % % NN cord-354133-11b0d499 277 11 , , , cord-354133-11b0d499 277 12 with with IN cord-354133-11b0d499 277 13 higher high JJR cord-354133-11b0d499 277 14 values value NNS cord-354133-11b0d499 277 15 observed observe VBN cord-354133-11b0d499 277 16 for for IN cord-354133-11b0d499 277 17 countries country NNS cord-354133-11b0d499 277 18 that that WDT cord-354133-11b0d499 277 19 experienced experience VBD cord-354133-11b0d499 277 20 more more RBR cord-354133-11b0d499 277 21 severe severe JJ cord-354133-11b0d499 277 22 outbreaks outbreak NNS cord-354133-11b0d499 277 23 , , , cord-354133-11b0d499 277 24 perhaps perhaps RB cord-354133-11b0d499 277 25 reflecting reflect VBG cord-354133-11b0d499 277 26 the the DT cord-354133-11b0d499 277 27 negative negative JJ cord-354133-11b0d499 277 28 influence influence NN cord-354133-11b0d499 277 29 of of IN cord-354133-11b0d499 277 30 overwhelmed overwhelmed JJ cord-354133-11b0d499 277 31 health health NN cord-354133-11b0d499 277 32 systems system NNS cord-354133-11b0d499 277 33 and and CC cord-354133-11b0d499 277 34 the the DT cord-354133-11b0d499 277 35 spread spread NN cord-354133-11b0d499 277 36 of of IN cord-354133-11b0d499 277 37 disease disease NN cord-354133-11b0d499 277 38 to to IN cord-354133-11b0d499 277 39 more more RBR cord-354133-11b0d499 277 40 vulnerable vulnerable JJ cord-354133-11b0d499 277 41 populations population NNS cord-354133-11b0d499 277 42 . . . cord-354133-11b0d499 278 1 The the DT cord-354133-11b0d499 278 2 calculated calculate VBN cord-354133-11b0d499 278 3 time time NN cord-354133-11b0d499 278 4 delay delay NN cord-354133-11b0d499 278 5 is be VBZ cord-354133-11b0d499 278 6 also also RB cord-354133-11b0d499 278 7 potentially potentially RB cord-354133-11b0d499 278 8 informative informative JJ cord-354133-11b0d499 278 9 ; ; : cord-354133-11b0d499 278 10 for for IN cord-354133-11b0d499 278 11 example example NN cord-354133-11b0d499 278 12 , , , cord-354133-11b0d499 278 13 the the DT cord-354133-11b0d499 278 14 one one CD cord-354133-11b0d499 278 15 - - HYPH cord-354133-11b0d499 278 16 day day NN cord-354133-11b0d499 278 17 delay delay NN cord-354133-11b0d499 278 18 calculated calculate VBN cord-354133-11b0d499 278 19 from from IN cord-354133-11b0d499 278 20 early early JJ cord-354133-11b0d499 278 21 data datum NNS cord-354133-11b0d499 278 22 in in IN cord-354133-11b0d499 278 23 Spain Spain NNP cord-354133-11b0d499 278 24 reflects reflect VBZ cord-354133-11b0d499 278 25 the the DT cord-354133-11b0d499 278 26 breakdown breakdown NN cord-354133-11b0d499 278 27 of of IN cord-354133-11b0d499 278 28 testing testing NN cord-354133-11b0d499 278 29 and and CC cord-354133-11b0d499 278 30 reporting report VBG cord-354133-11b0d499 278 31 systems system NNS cord-354133-11b0d499 278 32 at at IN cord-354133-11b0d499 278 33 that that DT cord-354133-11b0d499 278 34 time time NN cord-354133-11b0d499 278 35 , , , cord-354133-11b0d499 278 36 whereas whereas IN cord-354133-11b0d499 278 37 the the DT cord-354133-11b0d499 278 38 revised revise VBN cord-354133-11b0d499 278 39 delay delay NN cord-354133-11b0d499 278 40 time time NN cord-354133-11b0d499 278 41 of of IN cord-354133-11b0d499 278 42 14 14 CD cord-354133-11b0d499 278 43 days day NNS cord-354133-11b0d499 278 44 shows show VBZ cord-354133-11b0d499 278 45 the the DT cord-354133-11b0d499 278 46 recovery recovery NN cord-354133-11b0d499 278 47 of of IN cord-354133-11b0d499 278 48 the the DT cord-354133-11b0d499 278 49 system system NN cord-354133-11b0d499 278 50 and and CC cord-354133-11b0d499 278 51 the the DT cord-354133-11b0d499 278 52 likely likely JJ cord-354133-11b0d499 278 53 delay delay NN cord-354133-11b0d499 278 54 between between IN cord-354133-11b0d499 278 55 case case NN cord-354133-11b0d499 278 56 diagnosis diagnosis NN cord-354133-11b0d499 278 57 and and CC cord-354133-11b0d499 278 58 death death NN cord-354133-11b0d499 278 59 . . . cord-354133-11b0d499 279 1 In in IN cord-354133-11b0d499 279 2 this this DT cord-354133-11b0d499 279 3 way way NN cord-354133-11b0d499 279 4 , , , cord-354133-11b0d499 279 5 TSD TSD NNP cord-354133-11b0d499 279 6 analysis analysis NN cord-354133-11b0d499 279 7 of of IN cord-354133-11b0d499 279 8 data datum NNS cord-354133-11b0d499 279 9 from from IN cord-354133-11b0d499 279 10 a a DT cord-354133-11b0d499 279 11 particular particular JJ cord-354133-11b0d499 279 12 place place NN cord-354133-11b0d499 279 13 at at IN cord-354133-11b0d499 279 14 a a DT cord-354133-11b0d499 279 15 particular particular JJ cord-354133-11b0d499 279 16 time time NN cord-354133-11b0d499 279 17 can can MD cord-354133-11b0d499 279 18 give give VB cord-354133-11b0d499 279 19 useful useful JJ cord-354133-11b0d499 279 20 local local JJ cord-354133-11b0d499 279 21 information information NN cord-354133-11b0d499 279 22 on on IN cord-354133-11b0d499 279 23 the the DT cord-354133-11b0d499 279 24 progression progression NN cord-354133-11b0d499 279 25 of of IN cord-354133-11b0d499 279 26 an an DT cord-354133-11b0d499 279 27 outbreak outbreak NN cord-354133-11b0d499 279 28 to to TO cord-354133-11b0d499 279 29 inform inform VB cord-354133-11b0d499 279 30 public public JJ cord-354133-11b0d499 279 31 health health NN cord-354133-11b0d499 279 32 planning planning NN cord-354133-11b0d499 279 33 and and CC cord-354133-11b0d499 279 34 policy policy NN cord-354133-11b0d499 279 35 . . . cord-354133-11b0d499 280 1 are be VBP cord-354133-11b0d499 280 2 from from IN cord-354133-11b0d499 280 3 the the DT cord-354133-11b0d499 280 4 Economist Economist NNP cord-354133-11b0d499 280 5 's 's POS cord-354133-11b0d499 280 6 COVID-19 COVID-19 NNP cord-354133-11b0d499 280 7 excess excess JJ cord-354133-11b0d499 280 8 deaths death NNS cord-354133-11b0d499 280 9 tracker tracker NN cord-354133-11b0d499 280 10 repository repository NN cord-354133-11b0d499 280 11 at at IN cord-354133-11b0d499 280 12 https://github.com/TheEconomist/covid-19-excess-deaths-tracker https://github.com/TheEconomist/covid-19-excess-deaths-tracker NNP cord-354133-11b0d499 280 13 , , , cord-354133-11b0d499 280 14 and and CC cord-354133-11b0d499 280 15 positive positive JJ cord-354133-11b0d499 280 16 COVID-19 covid-19 JJ cord-354133-11b0d499 280 17 test test NN cord-354133-11b0d499 280 18 rates rate NNS cord-354133-11b0d499 280 19 are be VBP cord-354133-11b0d499 280 20 from from IN cord-354133-11b0d499 280 21 Our -PRON- PRP$ cord-354133-11b0d499 280 22 World World NNP cord-354133-11b0d499 280 23 in in IN cord-354133-11b0d499 280 24 Data Data NNP cord-354133-11b0d499 280 25 at at IN cord-354133-11b0d499 280 26 https://ourworldindata.org/coronavirus-testing https://ourworldindata.org/coronavirus-testing NN cord-354133-11b0d499 280 27 . . . cord-354133-11b0d499 281 1 is be VBZ cord-354133-11b0d499 281 2 the the DT cord-354133-11b0d499 281 3 author author NN cord-354133-11b0d499 281 4 / / SYM cord-354133-11b0d499 281 5 funder funder NN cord-354133-11b0d499 281 6 , , , cord-354133-11b0d499 281 7 who who WP cord-354133-11b0d499 281 8 has have VBZ cord-354133-11b0d499 281 9 granted grant VBN cord-354133-11b0d499 281 10 medRxiv medRxiv NNS cord-354133-11b0d499 281 11 a a DT cord-354133-11b0d499 281 12 license license NN cord-354133-11b0d499 281 13 to to TO cord-354133-11b0d499 281 14 display display VB cord-354133-11b0d499 281 15 the the DT cord-354133-11b0d499 281 16 preprint preprint NN cord-354133-11b0d499 281 17 in in IN cord-354133-11b0d499 281 18 ( ( -LRB- cord-354133-11b0d499 281 19 which which WDT cord-354133-11b0d499 281 20 was be VBD cord-354133-11b0d499 281 21 not not RB cord-354133-11b0d499 281 22 certified certify VBN cord-354133-11b0d499 281 23 by by IN cord-354133-11b0d499 281 24 peer peer NN cord-354133-11b0d499 281 25 review review NN cord-354133-11b0d499 281 26 ) ) -RRB- cord-354133-11b0d499 281 27 preprint preprint NN cord-354133-11b0d499 282 1 The the DT cord-354133-11b0d499 282 2 copyright copyright NN cord-354133-11b0d499 282 3 holder holder NN cord-354133-11b0d499 282 4 for for IN cord-354133-11b0d499 282 5 this this DT cord-354133-11b0d499 282 6 this this DT cord-354133-11b0d499 282 7 version version NN cord-354133-11b0d499 282 8 posted post VBD cord-354133-11b0d499 282 9 October October NNP cord-354133-11b0d499 282 10 27 27 CD cord-354133-11b0d499 282 11 , , , cord-354133-11b0d499 282 12 2020 2020 CD cord-354133-11b0d499 282 13 . . . cord-354133-11b0d499 283 1 is be VBZ cord-354133-11b0d499 283 2 the the DT cord-354133-11b0d499 283 3 author author NN cord-354133-11b0d499 283 4 / / SYM cord-354133-11b0d499 283 5 funder funder NN cord-354133-11b0d499 283 6 , , , cord-354133-11b0d499 283 7 who who WP cord-354133-11b0d499 283 8 has have VBZ cord-354133-11b0d499 283 9 granted grant VBN cord-354133-11b0d499 283 10 medRxiv medRxiv NNS cord-354133-11b0d499 283 11 a a DT cord-354133-11b0d499 283 12 license license NN cord-354133-11b0d499 283 13 to to TO cord-354133-11b0d499 283 14 display display VB cord-354133-11b0d499 283 15 the the DT cord-354133-11b0d499 283 16 preprint preprint NN cord-354133-11b0d499 283 17 in in IN cord-354133-11b0d499 283 18 ( ( -LRB- cord-354133-11b0d499 283 19 which which WDT cord-354133-11b0d499 283 20 was be VBD cord-354133-11b0d499 283 21 not not RB cord-354133-11b0d499 283 22 certified certify VBN cord-354133-11b0d499 283 23 by by IN cord-354133-11b0d499 283 24 peer peer NN cord-354133-11b0d499 283 25 review review NN cord-354133-11b0d499 283 26 ) ) -RRB- cord-354133-11b0d499 284 1 preprint preprint NN cord-354133-11b0d499 285 1 The the DT cord-354133-11b0d499 285 2 copyright copyright NN cord-354133-11b0d499 285 3 holder holder NN cord-354133-11b0d499 285 4 for for IN cord-354133-11b0d499 285 5 this this DT cord-354133-11b0d499 285 6 this this DT cord-354133-11b0d499 285 7 version version NN cord-354133-11b0d499 285 8 posted post VBD cord-354133-11b0d499 285 9 October October NNP cord-354133-11b0d499 285 10 27 27 CD cord-354133-11b0d499 285 11 , , , cord-354133-11b0d499 285 12 2020 2020 CD cord-354133-11b0d499 285 13 . . . cord-354133-11b0d499 286 1 ; ; : cord-354133-11b0d499 286 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 286 3 doi doi NN cord-354133-11b0d499 286 4 : : : cord-354133-11b0d499 287 1 medRxiv medRxiv NNP cord-354133-11b0d499 287 2 preprint preprint NN cord-354133-11b0d499 287 3 . . . cord-354133-11b0d499 288 1 CC CC NNP cord-354133-11b0d499 288 2 - - HYPH cord-354133-11b0d499 288 3 BY BY NNP cord-354133-11b0d499 288 4 - - HYPH cord-354133-11b0d499 288 5 NC NC NNP cord-354133-11b0d499 288 6 - - HYPH cord-354133-11b0d499 288 7 ND ND NNP cord-354133-11b0d499 288 8 4.0 4.0 CD cord-354133-11b0d499 288 9 International international JJ cord-354133-11b0d499 288 10 license license NN cord-354133-11b0d499 288 11 It -PRON- PRP cord-354133-11b0d499 288 12 is be VBZ cord-354133-11b0d499 288 13 made make VBN cord-354133-11b0d499 288 14 available available JJ cord-354133-11b0d499 288 15 under under IN cord-354133-11b0d499 288 16 a a DT cord-354133-11b0d499 288 17 perpetuity perpetuity NN cord-354133-11b0d499 288 18 . . . cord-354133-11b0d499 289 1 is be VBZ cord-354133-11b0d499 289 2 the the DT cord-354133-11b0d499 289 3 author author NN cord-354133-11b0d499 289 4 / / SYM cord-354133-11b0d499 289 5 funder funder NN cord-354133-11b0d499 289 6 , , , cord-354133-11b0d499 289 7 who who WP cord-354133-11b0d499 289 8 has have VBZ cord-354133-11b0d499 289 9 granted grant VBN cord-354133-11b0d499 289 10 medRxiv medRxiv NNS cord-354133-11b0d499 289 11 a a DT cord-354133-11b0d499 289 12 license license NN cord-354133-11b0d499 289 13 to to TO cord-354133-11b0d499 289 14 display display VB cord-354133-11b0d499 289 15 the the DT cord-354133-11b0d499 289 16 preprint preprint NN cord-354133-11b0d499 289 17 in in IN cord-354133-11b0d499 289 18 ( ( -LRB- cord-354133-11b0d499 289 19 which which WDT cord-354133-11b0d499 289 20 was be VBD cord-354133-11b0d499 289 21 not not RB cord-354133-11b0d499 289 22 certified certify VBN cord-354133-11b0d499 289 23 by by IN cord-354133-11b0d499 289 24 peer peer NN cord-354133-11b0d499 289 25 review review NN cord-354133-11b0d499 289 26 ) ) -RRB- cord-354133-11b0d499 289 27 preprint preprint NN cord-354133-11b0d499 290 1 The the DT cord-354133-11b0d499 290 2 copyright copyright NN cord-354133-11b0d499 290 3 holder holder NN cord-354133-11b0d499 290 4 for for IN cord-354133-11b0d499 290 5 this this DT cord-354133-11b0d499 290 6 this this DT cord-354133-11b0d499 290 7 version version NN cord-354133-11b0d499 290 8 posted post VBD cord-354133-11b0d499 290 9 October October NNP cord-354133-11b0d499 290 10 27 27 CD cord-354133-11b0d499 290 11 , , , cord-354133-11b0d499 290 12 2020 2020 CD cord-354133-11b0d499 290 13 . . . cord-354133-11b0d499 291 1 ; ; : cord-354133-11b0d499 291 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 291 3 doi doi NN cord-354133-11b0d499 291 4 : : : cord-354133-11b0d499 292 1 medRxiv medRxiv NNP cord-354133-11b0d499 292 2 preprint preprint NN cord-354133-11b0d499 292 3 . . . cord-354133-11b0d499 293 1 CC CC NNP cord-354133-11b0d499 293 2 - - HYPH cord-354133-11b0d499 293 3 BY BY NNP cord-354133-11b0d499 293 4 - - HYPH cord-354133-11b0d499 293 5 NC NC NNP cord-354133-11b0d499 293 6 - - HYPH cord-354133-11b0d499 293 7 ND ND NNP cord-354133-11b0d499 293 8 4.0 4.0 CD cord-354133-11b0d499 293 9 International international JJ cord-354133-11b0d499 293 10 license license NN cord-354133-11b0d499 293 11 It -PRON- PRP cord-354133-11b0d499 293 12 is be VBZ cord-354133-11b0d499 293 13 made make VBN cord-354133-11b0d499 293 14 available available JJ cord-354133-11b0d499 293 15 under under IN cord-354133-11b0d499 293 16 a a DT cord-354133-11b0d499 293 17 perpetuity perpetuity NN cord-354133-11b0d499 293 18 . . . cord-354133-11b0d499 294 1 is be VBZ cord-354133-11b0d499 294 2 the the DT cord-354133-11b0d499 294 3 author author NN cord-354133-11b0d499 294 4 / / SYM cord-354133-11b0d499 294 5 funder funder NN cord-354133-11b0d499 294 6 , , , cord-354133-11b0d499 294 7 who who WP cord-354133-11b0d499 294 8 has have VBZ cord-354133-11b0d499 294 9 granted grant VBN cord-354133-11b0d499 294 10 medRxiv medRxiv NNS cord-354133-11b0d499 294 11 a a DT cord-354133-11b0d499 294 12 license license NN cord-354133-11b0d499 294 13 to to TO cord-354133-11b0d499 294 14 display display VB cord-354133-11b0d499 294 15 the the DT cord-354133-11b0d499 294 16 preprint preprint NN cord-354133-11b0d499 294 17 in in IN cord-354133-11b0d499 294 18 ( ( -LRB- cord-354133-11b0d499 294 19 which which WDT cord-354133-11b0d499 294 20 was be VBD cord-354133-11b0d499 294 21 not not RB cord-354133-11b0d499 294 22 certified certify VBN cord-354133-11b0d499 294 23 by by IN cord-354133-11b0d499 294 24 peer peer NN cord-354133-11b0d499 294 25 review review NN cord-354133-11b0d499 294 26 ) ) -RRB- cord-354133-11b0d499 294 27 preprint preprint NN cord-354133-11b0d499 295 1 The the DT cord-354133-11b0d499 295 2 copyright copyright NN cord-354133-11b0d499 295 3 holder holder NN cord-354133-11b0d499 295 4 for for IN cord-354133-11b0d499 295 5 this this DT cord-354133-11b0d499 295 6 this this DT cord-354133-11b0d499 295 7 version version NN cord-354133-11b0d499 295 8 posted post VBD cord-354133-11b0d499 295 9 October October NNP cord-354133-11b0d499 295 10 27 27 CD cord-354133-11b0d499 295 11 , , , cord-354133-11b0d499 295 12 2020 2020 CD cord-354133-11b0d499 295 13 . . . cord-354133-11b0d499 296 1 ; ; : cord-354133-11b0d499 296 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 296 3 doi doi NN cord-354133-11b0d499 296 4 : : : cord-354133-11b0d499 297 1 medRxiv medRxiv NNP cord-354133-11b0d499 297 2 preprint preprint NN cord-354133-11b0d499 297 3 Early Early NNP cord-354133-11b0d499 297 4 Transmission Transmission NNP cord-354133-11b0d499 297 5 Dynamics Dynamics NNPS cord-354133-11b0d499 297 6 in in IN cord-354133-11b0d499 297 7 Wuhan Wuhan NNP cord-354133-11b0d499 297 8 , , , cord-354133-11b0d499 297 9 China China NNP cord-354133-11b0d499 297 10 , , , cord-354133-11b0d499 297 11 of of IN cord-354133-11b0d499 297 12 Novel Novel NNP cord-354133-11b0d499 297 13 Coronavirus Coronavirus NNP cord-354133-11b0d499 297 14 - - HYPH cord-354133-11b0d499 297 15 Infected infect VBN cord-354133-11b0d499 297 16 Pneumonia Pneumonia NNP cord-354133-11b0d499 297 17 Incubation Incubation NNP cord-354133-11b0d499 297 18 Period Period NNP cord-354133-11b0d499 297 19 and and CC cord-354133-11b0d499 297 20 Other other JJ cord-354133-11b0d499 297 21 Epidemiological epidemiological JJ cord-354133-11b0d499 297 22 Characteristics Characteristics NNPS cord-354133-11b0d499 297 23 of of IN cord-354133-11b0d499 297 24 Novel Novel NNP cord-354133-11b0d499 297 25 Coronavirus Coronavirus NNP cord-354133-11b0d499 297 26 Infections Infections NNPS cord-354133-11b0d499 297 27 with with IN cord-354133-11b0d499 297 28 Right Right NNP cord-354133-11b0d499 297 29 Truncation truncation NN cord-354133-11b0d499 297 30 : : : cord-354133-11b0d499 298 1 A a DT cord-354133-11b0d499 298 2 Statistical Statistical NNP cord-354133-11b0d499 298 3 Analysis Analysis NNP cord-354133-11b0d499 298 4 of of IN cord-354133-11b0d499 298 5 Publicly publicly RB cord-354133-11b0d499 298 6 Available Available NNP cord-354133-11b0d499 298 7 Case Case NNP cord-354133-11b0d499 298 8 Data Data NNP cord-354133-11b0d499 299 1 The the DT cord-354133-11b0d499 299 2 many many JJ cord-354133-11b0d499 299 3 estimates estimate NNS cord-354133-11b0d499 299 4 of of IN cord-354133-11b0d499 299 5 the the DT cord-354133-11b0d499 299 6 COVID-19 COVID-19 NNP cord-354133-11b0d499 299 7 case case NN cord-354133-11b0d499 299 8 fatality fatality NN cord-354133-11b0d499 299 9 rate rate NN cord-354133-11b0d499 299 10 . . . cord-354133-11b0d499 300 1 The the DT cord-354133-11b0d499 300 2 Lancet Lancet NNP cord-354133-11b0d499 301 1 On on IN cord-354133-11b0d499 301 2 Identifying identify VBG cord-354133-11b0d499 301 3 and and CC cord-354133-11b0d499 301 4 Mitigating mitigate VBG cord-354133-11b0d499 301 5 Bias Bias NNP cord-354133-11b0d499 301 6 in in IN cord-354133-11b0d499 301 7 the the DT cord-354133-11b0d499 301 8 Estimation Estimation NNP cord-354133-11b0d499 301 9 of of IN cord-354133-11b0d499 301 10 the the DT cord-354133-11b0d499 301 11 COVID-19 COVID-19 NNP cord-354133-11b0d499 301 12 Case Case NNP cord-354133-11b0d499 301 13 Fatality Fatality NNP cord-354133-11b0d499 301 14 Rate rate NN cord-354133-11b0d499 301 15 . . . cord-354133-11b0d499 302 1 Harvard Harvard NNP cord-354133-11b0d499 302 2 Data Data NNP cord-354133-11b0d499 302 3 Science Science NNP cord-354133-11b0d499 302 4 Review Review NNP cord-354133-11b0d499 302 5 Report Report NNP cord-354133-11b0d499 302 6 4 4 CD cord-354133-11b0d499 302 7 : : : cord-354133-11b0d499 302 8 severity severity NN cord-354133-11b0d499 302 9 of of IN cord-354133-11b0d499 302 10 2019-novel 2019-novel CD cord-354133-11b0d499 302 11 coronavirus coronavirus NN cord-354133-11b0d499 302 12 ( ( -LRB- cord-354133-11b0d499 302 13 nCoV ncov NN cord-354133-11b0d499 302 14 ) ) -RRB- cord-354133-11b0d499 303 1 Estimating estimate VBG cord-354133-11b0d499 303 2 Risk Risk NNP cord-354133-11b0d499 303 3 for for IN cord-354133-11b0d499 303 4 Death death NN cord-354133-11b0d499 303 5 from from IN cord-354133-11b0d499 303 6 Coronavirus Coronavirus NNP cord-354133-11b0d499 303 7 Disease Disease NNP cord-354133-11b0d499 303 8 , , , cord-354133-11b0d499 303 9 China China NNP cord-354133-11b0d499 303 10 Updated update VBD cord-354133-11b0d499 303 11 understanding understanding NN cord-354133-11b0d499 303 12 of of IN cord-354133-11b0d499 303 13 the the DT cord-354133-11b0d499 303 14 outbreak outbreak NN cord-354133-11b0d499 303 15 of of IN cord-354133-11b0d499 303 16 2019 2019 CD cord-354133-11b0d499 303 17 novel novel JJ cord-354133-11b0d499 303 18 coronavirus coronavirus NN cord-354133-11b0d499 303 19 ( ( -LRB- cord-354133-11b0d499 303 20 2019-nCoV 2019-ncov CD cord-354133-11b0d499 303 21 ) ) -RRB- cord-354133-11b0d499 303 22 in in IN cord-354133-11b0d499 303 23 Wuhan Wuhan NNP cord-354133-11b0d499 303 24 Estimating estimate VBG cord-354133-11b0d499 303 25 the the DT cord-354133-11b0d499 303 26 Risk Risk NNP cord-354133-11b0d499 303 27 of of IN cord-354133-11b0d499 303 28 COVID-19 COVID-19 NNP cord-354133-11b0d499 303 29 Death Death NNP cord-354133-11b0d499 304 1 During during IN cord-354133-11b0d499 304 2 the the DT cord-354133-11b0d499 304 3 Course course NN cord-354133-11b0d499 304 4 of of IN cord-354133-11b0d499 304 5 the the DT cord-354133-11b0d499 304 6 Outbreak outbreak NN cord-354133-11b0d499 304 7 in in IN cord-354133-11b0d499 304 8 Korea Korea NNP cord-354133-11b0d499 305 1 An an DT cord-354133-11b0d499 305 2 interactive interactive JJ cord-354133-11b0d499 305 3 web web NN cord-354133-11b0d499 305 4 - - HYPH cord-354133-11b0d499 305 5 based base VBN cord-354133-11b0d499 305 6 dashboard dashboard NN cord-354133-11b0d499 305 7 to to TO cord-354133-11b0d499 305 8 track track VB cord-354133-11b0d499 305 9 COVID-19 COVID-19 NNP cord-354133-11b0d499 305 10 in in IN cord-354133-11b0d499 305 11 real real JJ cord-354133-11b0d499 305 12 time time NN cord-354133-11b0d499 305 13 Methods method NNS cord-354133-11b0d499 305 14 for for IN cord-354133-11b0d499 305 15 estimating estimate VBG cord-354133-11b0d499 305 16 the the DT cord-354133-11b0d499 305 17 case case NN cord-354133-11b0d499 305 18 fatality fatality NN cord-354133-11b0d499 305 19 ratio ratio NN cord-354133-11b0d499 305 20 for for IN cord-354133-11b0d499 305 21 a a DT cord-354133-11b0d499 305 22 novel novel NN cord-354133-11b0d499 305 23 , , , cord-354133-11b0d499 305 24 emerging emerge VBG cord-354133-11b0d499 305 25 infectious infectious JJ cord-354133-11b0d499 305 26 disease disease NN cord-354133-11b0d499 305 27 Clinical clinical JJ cord-354133-11b0d499 305 28 course course NN cord-354133-11b0d499 305 29 and and CC cord-354133-11b0d499 305 30 outcomes outcome NNS cord-354133-11b0d499 305 31 of of IN cord-354133-11b0d499 305 32 critically critically RB cord-354133-11b0d499 305 33 ill ill JJ cord-354133-11b0d499 305 34 patients patient NNS cord-354133-11b0d499 305 35 with with IN cord-354133-11b0d499 305 36 SARS SARS NNP cord-354133-11b0d499 305 37 - - HYPH cord-354133-11b0d499 305 38 CoV-2 CoV-2 NNP cord-354133-11b0d499 305 39 pneumonia pneumonia NN cord-354133-11b0d499 305 40 in in IN cord-354133-11b0d499 305 41 Wuhan Wuhan NNP cord-354133-11b0d499 305 42 , , , cord-354133-11b0d499 305 43 China China NNP cord-354133-11b0d499 305 44 : : : cord-354133-11b0d499 305 45 a a DT cord-354133-11b0d499 305 46 single single RB cord-354133-11b0d499 305 47 - - HYPH cord-354133-11b0d499 305 48 centered centered JJ cord-354133-11b0d499 305 49 , , , cord-354133-11b0d499 305 50 retrospective retrospective JJ cord-354133-11b0d499 305 51 , , , cord-354133-11b0d499 305 52 observational observational JJ cord-354133-11b0d499 305 53 study study NN cord-354133-11b0d499 305 54 Case case NN cord-354133-11b0d499 305 55 - - HYPH cord-354133-11b0d499 305 56 fatality fatality NN cord-354133-11b0d499 305 57 rate rate NN cord-354133-11b0d499 305 58 and and CC cord-354133-11b0d499 305 59 characteristics characteristic NNS cord-354133-11b0d499 305 60 of of IN cord-354133-11b0d499 305 61 patients patient NNS cord-354133-11b0d499 305 62 dying die VBG cord-354133-11b0d499 305 63 in in IN cord-354133-11b0d499 305 64 relation relation NN cord-354133-11b0d499 305 65 to to IN cord-354133-11b0d499 305 66 COVID-19 covid-19 VB cord-354133-11b0d499 305 67 in in IN cord-354133-11b0d499 305 68 Italy Italy NNP cord-354133-11b0d499 305 69 Monitoring Monitoring NNP cord-354133-11b0d499 305 70 transmissibility transmissibility NN cord-354133-11b0d499 305 71 and and CC cord-354133-11b0d499 305 72 mortality mortality NN cord-354133-11b0d499 305 73 of of IN cord-354133-11b0d499 305 74 COVID-19 COVID-19 NNP cord-354133-11b0d499 305 75 in in IN cord-354133-11b0d499 305 76 Europe Europe NNP cord-354133-11b0d499 305 77 Case Case NNP cord-354133-11b0d499 305 78 - - HYPH cord-354133-11b0d499 305 79 fatality fatality NN cord-354133-11b0d499 305 80 risk risk NN cord-354133-11b0d499 305 81 estimates estimate NNS cord-354133-11b0d499 305 82 for for IN cord-354133-11b0d499 305 83 COVID-19 covid-19 NN cord-354133-11b0d499 305 84 calculated calculate VBN cord-354133-11b0d499 305 85 by by IN cord-354133-11b0d499 305 86 using use VBG cord-354133-11b0d499 305 87 a a DT cord-354133-11b0d499 305 88 lag lag NN cord-354133-11b0d499 305 89 time time NN cord-354133-11b0d499 305 90 for for IN cord-354133-11b0d499 305 91 fatality fatality NN cord-354133-11b0d499 305 92 World World NNP cord-354133-11b0d499 305 93 Health Health NNP cord-354133-11b0d499 305 94 Organization Organization NNP cord-354133-11b0d499 305 95 . . . cord-354133-11b0d499 306 1 Cumulative cumulative JJ cord-354133-11b0d499 306 2 Number number NN cord-354133-11b0d499 306 3 of of IN cord-354133-11b0d499 306 4 Reported reported JJ cord-354133-11b0d499 306 5 Probable probable JJ cord-354133-11b0d499 306 6 Cases case NNS cord-354133-11b0d499 306 7 of of IN cord-354133-11b0d499 306 8 Severe severe JJ cord-354133-11b0d499 306 9 Acute acute JJ cord-354133-11b0d499 306 10 Respiratory Respiratory NNP cord-354133-11b0d499 306 11 Syndrome Syndrome NNP cord-354133-11b0d499 306 12 ( ( -LRB- cord-354133-11b0d499 306 13 SARS SARS NNP cord-354133-11b0d499 306 14 ) ) -RRB- cord-354133-11b0d499 307 1 Epidemiological epidemiological JJ cord-354133-11b0d499 307 2 determinants determinant NNS cord-354133-11b0d499 307 3 of of IN cord-354133-11b0d499 307 4 spread spread NN cord-354133-11b0d499 307 5 of of IN cord-354133-11b0d499 307 6 causal causal JJ cord-354133-11b0d499 307 7 agent agent NN cord-354133-11b0d499 307 8 of of IN cord-354133-11b0d499 307 9 severe severe JJ cord-354133-11b0d499 307 10 acute acute JJ cord-354133-11b0d499 307 11 respiratory respiratory JJ cord-354133-11b0d499 307 12 syndrome syndrome NN cord-354133-11b0d499 307 13 in in IN cord-354133-11b0d499 307 14 Hong Hong NNP cord-354133-11b0d499 307 15 Kong Kong NNP cord-354133-11b0d499 308 1 Early early JJ cord-354133-11b0d499 308 2 epidemiological epidemiological JJ cord-354133-11b0d499 308 3 assessment assessment NN cord-354133-11b0d499 308 4 of of IN cord-354133-11b0d499 308 5 the the DT cord-354133-11b0d499 308 6 virulence virulence NN cord-354133-11b0d499 308 7 of of IN cord-354133-11b0d499 308 8 emerging emerge VBG cord-354133-11b0d499 308 9 infectious infectious JJ cord-354133-11b0d499 308 10 diseases disease NNS cord-354133-11b0d499 308 11 : : : cord-354133-11b0d499 308 12 a a DT cord-354133-11b0d499 308 13 case case NN cord-354133-11b0d499 308 14 study study NN cord-354133-11b0d499 308 15 of of IN cord-354133-11b0d499 308 16 an an DT cord-354133-11b0d499 308 17 influenza influenza NN cord-354133-11b0d499 308 18 pandemic pandemic NN cord-354133-11b0d499 308 19 COVID-19 covid-19 CD cord-354133-11b0d499 308 20 ) ) -RRB- cord-354133-11b0d499 308 21 Mortality mortality NN cord-354133-11b0d499 308 22 Rate rate NN cord-354133-11b0d499 308 23 Coronavirus Coronavirus NNP cord-354133-11b0d499 308 24 disease disease NN cord-354133-11b0d499 308 25 ( ( -LRB- cord-354133-11b0d499 308 26 COVID-19 COVID-19 NNP cord-354133-11b0d499 308 27 ) ) -RRB- cord-354133-11b0d499 308 28 : : : cord-354133-11b0d499 309 1 Log Log NNP cord-354133-11b0d499 309 2 of of IN cord-354133-11b0d499 309 3 major major JJ cord-354133-11b0d499 309 4 changes change NNS cord-354133-11b0d499 309 5 and and CC cord-354133-11b0d499 309 6 errata errata NN cord-354133-11b0d499 309 7 in in IN cord-354133-11b0d499 309 8 WHO WHO NNP cord-354133-11b0d499 309 9 daily daily JJ cord-354133-11b0d499 309 10 aggregate aggregate NN cord-354133-11b0d499 309 11 case case NN cord-354133-11b0d499 309 12 and and CC cord-354133-11b0d499 309 13 death death NN cord-354133-11b0d499 309 14 count count NN cord-354133-11b0d499 309 15 data datum NNS cord-354133-11b0d499 309 16 A a DT cord-354133-11b0d499 309 17 novel novel JJ cord-354133-11b0d499 309 18 comprehensive comprehensive JJ cord-354133-11b0d499 309 19 metric metric NN cord-354133-11b0d499 309 20 to to TO cord-354133-11b0d499 309 21 assess assess VB cord-354133-11b0d499 309 22 COVID-19 covid-19 JJ cord-354133-11b0d499 309 23 testing testing NN cord-354133-11b0d499 309 24 outcomes outcome NNS cord-354133-11b0d499 309 25 : : : cord-354133-11b0d499 309 26 Effects effect NNS cord-354133-11b0d499 309 27 of of IN cord-354133-11b0d499 309 28 geography geography NN cord-354133-11b0d499 309 29 , , , cord-354133-11b0d499 309 30 government government NN cord-354133-11b0d499 309 31 , , , cord-354133-11b0d499 309 32 and and CC cord-354133-11b0d499 309 33 policy policy NN cord-354133-11b0d499 309 34 response response NN cord-354133-11b0d499 309 35 Infection infection NN cord-354133-11b0d499 309 36 fatality fatality NN cord-354133-11b0d499 309 37 rate rate NN cord-354133-11b0d499 309 38 of of IN cord-354133-11b0d499 309 39 COVID-19 COVID-19 NNP cord-354133-11b0d499 309 40 inferred infer VBN cord-354133-11b0d499 309 41 from from IN cord-354133-11b0d499 309 42 seroprevalence seroprevalence NN cord-354133-11b0d499 309 43 data datum NNS cord-354133-11b0d499 309 44 . . . cord-354133-11b0d499 310 1 Bulletin bulletin NN cord-354133-11b0d499 310 2 of of IN cord-354133-11b0d499 310 3 the the DT cord-354133-11b0d499 310 4 World World NNP cord-354133-11b0d499 310 5 Health Health NNP cord-354133-11b0d499 310 6 Organization Organization NNP cord-354133-11b0d499 310 7 2020 2020 CD cord-354133-11b0d499 310 8 : : : cord-354133-11b0d499 311 1 Article article NN cord-354133-11b0d499 311 2 ID id NN cord-354133-11b0d499 311 3 BLT BLT NNP cord-354133-11b0d499 312 1 Substantial substantial JJ cord-354133-11b0d499 312 2 undocumented undocumented JJ cord-354133-11b0d499 312 3 infection infection NN cord-354133-11b0d499 312 4 facilitates facilitate VBZ cord-354133-11b0d499 312 5 the the DT cord-354133-11b0d499 312 6 rapid rapid JJ cord-354133-11b0d499 312 7 dissemination dissemination NN cord-354133-11b0d499 312 8 of of IN cord-354133-11b0d499 312 9 novel novel JJ cord-354133-11b0d499 312 10 coronavirus coronavirus NN cord-354133-11b0d499 312 11 ( ( -LRB- cord-354133-11b0d499 312 12 SARS SARS NNP cord-354133-11b0d499 312 13 - - HYPH cord-354133-11b0d499 312 14 CoV-2 CoV-2 NNP cord-354133-11b0d499 312 15 ) ) -RRB- cord-354133-11b0d499 313 1 Substantial substantial JJ cord-354133-11b0d499 313 2 underestimation underestimation NN cord-354133-11b0d499 313 3 of of IN cord-354133-11b0d499 313 4 SARS SARS NNP cord-354133-11b0d499 313 5 - - HYPH cord-354133-11b0d499 313 6 CoV-2 CoV-2 NNP cord-354133-11b0d499 313 7 infection infection NN cord-354133-11b0d499 313 8 in in IN cord-354133-11b0d499 313 9 the the DT cord-354133-11b0d499 313 10 United United NNP cord-354133-11b0d499 313 11 States States NNP cord-354133-11b0d499 314 1 How how WRB cord-354133-11b0d499 314 2 accurate accurate JJ cord-354133-11b0d499 314 3 are be VBP cord-354133-11b0d499 314 4 Australia Australia NNP cord-354133-11b0d499 314 5 's 's POS cord-354133-11b0d499 314 6 coronavirus coronavirus NN cord-354133-11b0d499 314 7 numbers number NNS cord-354133-11b0d499 314 8 ? ? . cord-354133-11b0d499 315 1 The the DT cord-354133-11b0d499 315 2 answer answer NN cord-354133-11b0d499 315 3 lies lie VBZ cord-354133-11b0d499 315 4 in in IN cord-354133-11b0d499 315 5 our -PRON- PRP$ cord-354133-11b0d499 315 6 death death NN cord-354133-11b0d499 315 7 data datum NNS cord-354133-11b0d499 315 8 Suppression suppression NN cord-354133-11b0d499 315 9 of of IN cord-354133-11b0d499 315 10 a a DT cord-354133-11b0d499 315 11 SARS SARS NNP cord-354133-11b0d499 315 12 - - HYPH cord-354133-11b0d499 315 13 CoV-2 CoV-2 NNP cord-354133-11b0d499 315 14 outbreak outbreak NN cord-354133-11b0d499 315 15 in in IN cord-354133-11b0d499 315 16 the the DT cord-354133-11b0d499 315 17 Italian italian JJ cord-354133-11b0d499 315 18 municipality municipality NN cord-354133-11b0d499 315 19 of of IN cord-354133-11b0d499 315 20 Vo Vo NNP cord-354133-11b0d499 315 21 ' ' POS cord-354133-11b0d499 315 22 A a DT cord-354133-11b0d499 315 23 dual dual JJ cord-354133-11b0d499 315 24 antigen antigen NN cord-354133-11b0d499 315 25 ELISA ELISA NNP cord-354133-11b0d499 315 26 allows allow VBZ cord-354133-11b0d499 315 27 the the DT cord-354133-11b0d499 315 28 assessment assessment NN cord-354133-11b0d499 315 29 of of IN cord-354133-11b0d499 315 30 SARS SARS NNP cord-354133-11b0d499 315 31 - - HYPH cord-354133-11b0d499 315 32 CoV-2 CoV-2 NNP cord-354133-11b0d499 315 33 antibody antibody NN cord-354133-11b0d499 315 34 seroprevalence seroprevalence NN cord-354133-11b0d499 315 35 in in IN cord-354133-11b0d499 315 36 a a DT cord-354133-11b0d499 315 37 low low JJ cord-354133-11b0d499 315 38 transmission transmission NN cord-354133-11b0d499 315 39 setting set VBG cord-354133-11b0d499 315 40 Simpson Simpson NNP cord-354133-11b0d499 315 41 's 's POS cord-354133-11b0d499 315 42 paradox paradox NN cord-354133-11b0d499 315 43 in in IN cord-354133-11b0d499 315 44 Covid-19 covid-19 NN cord-354133-11b0d499 315 45 case case NN cord-354133-11b0d499 315 46 fatality fatality NN cord-354133-11b0d499 315 47 rates rate NNS cord-354133-11b0d499 315 48 : : : cord-354133-11b0d499 315 49 a a DT cord-354133-11b0d499 315 50 mediation mediation NN cord-354133-11b0d499 315 51 analysis analysis NN cord-354133-11b0d499 315 52 of of IN cord-354133-11b0d499 315 53 age age NN cord-354133-11b0d499 315 54 - - HYPH cord-354133-11b0d499 315 55 related relate VBN cord-354133-11b0d499 315 56 causal causal NN cord-354133-11b0d499 315 57 effects effect NNS cord-354133-11b0d499 315 58 Our -PRON- PRP$ cord-354133-11b0d499 315 59 World World NNP cord-354133-11b0d499 315 60 in in IN cord-354133-11b0d499 315 61 Data Data NNP cord-354133-11b0d499 315 62 . . . cord-354133-11b0d499 316 1 Coronavirus Coronavirus NNP cord-354133-11b0d499 316 2 ( ( -LRB- cord-354133-11b0d499 316 3 COVID-19 covid-19 VB cord-354133-11b0d499 316 4 ) ) -RRB- cord-354133-11b0d499 316 5 Testing Testing NNP cord-354133-11b0d499 316 6 Seroprevalence Seroprevalence NNP cord-354133-11b0d499 316 7 of of IN cord-354133-11b0d499 316 8 Antibodies Antibodies NNPS cord-354133-11b0d499 316 9 to to IN cord-354133-11b0d499 316 10 SARS SARS NNP cord-354133-11b0d499 316 11 - - HYPH cord-354133-11b0d499 316 12 CoV-2 CoV-2 NNP cord-354133-11b0d499 316 13 in in IN cord-354133-11b0d499 316 14 10 10 CD cord-354133-11b0d499 316 15 Sites site NNS cord-354133-11b0d499 316 16 in in IN cord-354133-11b0d499 316 17 the the DT cord-354133-11b0d499 316 18 United United NNP cord-354133-11b0d499 316 19 States States NNP cord-354133-11b0d499 316 20 The the DT cord-354133-11b0d499 316 21 Economist Economist NNP cord-354133-11b0d499 316 22 . . . cord-354133-11b0d499 317 1 Tracking track VBG cord-354133-11b0d499 317 2 covid-19 covid-19 NN cord-354133-11b0d499 317 3 excess excess JJ cord-354133-11b0d499 317 4 deaths death NNS cord-354133-11b0d499 317 5 across across IN cord-354133-11b0d499 317 6 countries country NNS cord-354133-11b0d499 317 7 Cumulative cumulative JJ cord-354133-11b0d499 317 8 incidence incidence NN cord-354133-11b0d499 317 9 and and CC cord-354133-11b0d499 317 10 diagnosis diagnosis NN cord-354133-11b0d499 317 11 of of IN cord-354133-11b0d499 317 12 SARS SARS NNP cord-354133-11b0d499 317 13 - - HYPH cord-354133-11b0d499 317 14 CoV-2 CoV-2 NNP cord-354133-11b0d499 317 15 infection infection NN cord-354133-11b0d499 317 16 in in IN cord-354133-11b0d499 317 17 New New NNP cord-354133-11b0d499 317 18 York York NNP cord-354133-11b0d499 318 1 Amid amid IN cord-354133-11b0d499 318 2 Ongoing ongoing JJ cord-354133-11b0d499 318 3 COVID-19 COVID-19 NNP cord-354133-11b0d499 318 4 Pandemic Pandemic NNP cord-354133-11b0d499 318 5 , , , cord-354133-11b0d499 318 6 Governor Governor NNP cord-354133-11b0d499 318 7 Cuomo Cuomo NNP cord-354133-11b0d499 318 8 Announces announce VBZ cord-354133-11b0d499 318 9 Results result NNS cord-354133-11b0d499 318 10 of of IN cord-354133-11b0d499 318 11 Completed Completed NNP cord-354133-11b0d499 318 12 Antibody Antibody NNP cord-354133-11b0d499 318 13 Testing Testing NNP cord-354133-11b0d499 318 14 Study Study NNP cord-354133-11b0d499 318 15 of of IN cord-354133-11b0d499 318 16 15,000 15,000 CD cord-354133-11b0d499 318 17 People People NNS cord-354133-11b0d499 318 18 Showing show VBG cord-354133-11b0d499 318 19 12.3 12.3 CD cord-354133-11b0d499 318 20 . . . cord-354133-11b0d499 319 1 CC CC NNP cord-354133-11b0d499 319 2 - - HYPH cord-354133-11b0d499 319 3 BY BY NNP cord-354133-11b0d499 319 4 - - HYPH cord-354133-11b0d499 319 5 NC NC NNP cord-354133-11b0d499 319 6 - - HYPH cord-354133-11b0d499 319 7 ND ND NNP cord-354133-11b0d499 319 8 4.0 4.0 CD cord-354133-11b0d499 319 9 International International NNP cord-354133-11b0d499 319 10 license license NN cord-354133-11b0d499 319 11 Percent Percent NNP cord-354133-11b0d499 319 12 of of IN cord-354133-11b0d499 319 13 Population Population NNP cord-354133-11b0d499 319 14 Has have VBZ cord-354133-11b0d499 319 15 COVID-19 covid-19 CD cord-354133-11b0d499 319 16 Antibodies Antibodies NNP cord-354133-11b0d499 319 17 Infection infection NN cord-354133-11b0d499 319 18 fatality fatality NN cord-354133-11b0d499 319 19 rate rate NN cord-354133-11b0d499 319 20 of of IN cord-354133-11b0d499 319 21 SARS SARS NNP cord-354133-11b0d499 319 22 - - HYPH cord-354133-11b0d499 319 23 CoV-2 CoV-2 NNP cord-354133-11b0d499 319 24 infection infection NN cord-354133-11b0d499 319 25 in in IN cord-354133-11b0d499 319 26 a a DT cord-354133-11b0d499 319 27 German german JJ cord-354133-11b0d499 319 28 community community NN cord-354133-11b0d499 319 29 with with IN cord-354133-11b0d499 319 30 a a DT cord-354133-11b0d499 319 31 super super RB cord-354133-11b0d499 319 32 - - JJ cord-354133-11b0d499 319 33 spreading spread VBG cord-354133-11b0d499 319 34 event event NN cord-354133-11b0d499 319 35 Seroprevalence Seroprevalence NNP cord-354133-11b0d499 319 36 of of IN cord-354133-11b0d499 319 37 anti anti JJ cord-354133-11b0d499 319 38 - - JJ cord-354133-11b0d499 319 39 SARS SARS NNP cord-354133-11b0d499 319 40 - - HYPH cord-354133-11b0d499 319 41 CoV-2 CoV-2 NNP cord-354133-11b0d499 319 42 IgG igg NN cord-354133-11b0d499 319 43 antibodies antibody NNS cord-354133-11b0d499 319 44 in in IN cord-354133-11b0d499 319 45 Geneva Geneva NNP cord-354133-11b0d499 319 46 , , , cord-354133-11b0d499 319 47 Switzerland Switzerland NNP cord-354133-11b0d499 319 48 ( ( -LRB- cord-354133-11b0d499 319 49 SEROCoV SEROCoV NNP cord-354133-11b0d499 319 50 - - HYPH cord-354133-11b0d499 319 51 POP pop NN cord-354133-11b0d499 319 52 ) ) -RRB- cord-354133-11b0d499 319 53 : : : cord-354133-11b0d499 319 54 a a DT cord-354133-11b0d499 319 55 population population NN cord-354133-11b0d499 319 56 - - HYPH cord-354133-11b0d499 319 57 based base VBN cord-354133-11b0d499 319 58 study study NN cord-354133-11b0d499 319 59 Public Public NNP cord-354133-11b0d499 319 60 Health Health NNP cord-354133-11b0d499 319 61 Agency Agency NNP cord-354133-11b0d499 319 62 of of IN cord-354133-11b0d499 319 63 Sweden Sweden NNP cord-354133-11b0d499 319 64 ) ) -RRB- cord-354133-11b0d499 319 65 . . . cord-354133-11b0d499 320 1 Första Första NNP cord-354133-11b0d499 320 2 resultaten resultaten NNP cord-354133-11b0d499 320 3 om om NNP cord-354133-11b0d499 320 4 antikroppar antikroppar NNP cord-354133-11b0d499 320 5 efter efter NNP cord-354133-11b0d499 320 6 genomgången genomgången NNP cord-354133-11b0d499 321 1 covid-19 covid-19 NNP cord-354133-11b0d499 321 2 hos hos NNP cord-354133-11b0d499 321 3 blodgivare blodgivare NN cord-354133-11b0d499 321 4 Antibody antibody NN cord-354133-11b0d499 321 5 prevalence prevalence NN cord-354133-11b0d499 321 6 for for IN cord-354133-11b0d499 321 7 SARS SARS NNP cord-354133-11b0d499 321 8 - - HYPH cord-354133-11b0d499 321 9 CoV-2 CoV-2 NNP cord-354133-11b0d499 321 10 in in IN cord-354133-11b0d499 321 11 England England NNP cord-354133-11b0d499 321 12 following follow VBG cord-354133-11b0d499 321 13 first first JJ cord-354133-11b0d499 321 14 peak peak NN cord-354133-11b0d499 321 15 of of IN cord-354133-11b0d499 321 16 the the DT cord-354133-11b0d499 321 17 pandemic pandemic NN cord-354133-11b0d499 321 18 : : : cord-354133-11b0d499 322 1 REACT2 REACT2 : cord-354133-11b0d499 322 2 study study VB cord-354133-11b0d499 322 3 in in IN cord-354133-11b0d499 322 4 100,000 100,000 CD cord-354133-11b0d499 322 5 adults adult NNS cord-354133-11b0d499 322 6 Seroprevalence Seroprevalence NNP cord-354133-11b0d499 322 7 of of IN cord-354133-11b0d499 322 8 IgG IgG NNP cord-354133-11b0d499 322 9 antibodies antibody NNS cord-354133-11b0d499 322 10 against against IN cord-354133-11b0d499 322 11 SARS SARS NNP cord-354133-11b0d499 322 12 coronavirus coronavirus NN cord-354133-11b0d499 322 13 2 2 CD cord-354133-11b0d499 322 14 in in IN cord-354133-11b0d499 322 15 Belgium Belgium NNP cord-354133-11b0d499 322 16 : : : cord-354133-11b0d499 322 17 a a DT cord-354133-11b0d499 322 18 prospective prospective JJ cord-354133-11b0d499 322 19 cross cross JJ cord-354133-11b0d499 322 20 - - JJ cord-354133-11b0d499 322 21 sectional sectional JJ cord-354133-11b0d499 322 22 study study NN cord-354133-11b0d499 322 23 of of IN cord-354133-11b0d499 322 24 residual residual JJ cord-354133-11b0d499 322 25 samples sample NNS cord-354133-11b0d499 322 26 Prevalence prevalence NN cord-354133-11b0d499 322 27 of of IN cord-354133-11b0d499 322 28 SARS SARS NNP cord-354133-11b0d499 322 29 - - HYPH cord-354133-11b0d499 322 30 CoV-2 CoV-2 NNP cord-354133-11b0d499 322 31 in in IN cord-354133-11b0d499 322 32 Spain Spain NNP cord-354133-11b0d499 323 1 ( ( -LRB- cord-354133-11b0d499 323 2 ENE ENE NNP cord-354133-11b0d499 323 3 - - HYPH cord-354133-11b0d499 323 4 COVID COVID NNP cord-354133-11b0d499 323 5 ) ) -RRB- cord-354133-11b0d499 323 6 : : : cord-354133-11b0d499 324 1 a a DT cord-354133-11b0d499 324 2 nationwide nationwide JJ cord-354133-11b0d499 324 3 , , , cord-354133-11b0d499 324 4 population population NN cord-354133-11b0d499 324 5 - - HYPH cord-354133-11b0d499 324 6 based base VBN cord-354133-11b0d499 324 7 seroepidemiological seroepidemiological JJ cord-354133-11b0d499 324 8 study study NN cord-354133-11b0d499 324 9 SARS SARS NNP cord-354133-11b0d499 324 10 - - HYPH cord-354133-11b0d499 324 11 CoV-2 CoV-2 NNP cord-354133-11b0d499 324 12 infection infection NN cord-354133-11b0d499 324 13 fatality fatality NN cord-354133-11b0d499 324 14 risk risk NN cord-354133-11b0d499 324 15 in in IN cord-354133-11b0d499 324 16 a a DT cord-354133-11b0d499 324 17 nationwide nationwide JJ cord-354133-11b0d499 324 18 seroepidemiological seroepidemiological JJ cord-354133-11b0d499 324 19 study study NN cord-354133-11b0d499 324 20 Primi Primi NNP cord-354133-11b0d499 324 21 risultati risultati NNP cord-354133-11b0d499 324 22 dell'indagine dell'indagine NNP cord-354133-11b0d499 325 1 di di NNP cord-354133-11b0d499 325 2 sieroprevalenza sieroprevalenza NNP cord-354133-11b0d499 326 1 SARS SARS NNP cord-354133-11b0d499 326 2 - - HYPH cord-354133-11b0d499 326 3 CoV-2 CoV-2 NNP cord-354133-11b0d499 326 4 Seroprevalence Seroprevalence NNP cord-354133-11b0d499 326 5 of of IN cord-354133-11b0d499 326 6 SARS SARS NNP cord-354133-11b0d499 326 7 - - : cord-354133-11b0d499 326 8 CoV-2 CoV-2 NNP cord-354133-11b0d499 326 9 significantly significantly RB cord-354133-11b0d499 326 10 varies vary VBZ cord-354133-11b0d499 326 11 with with IN cord-354133-11b0d499 326 12 age age NN cord-354133-11b0d499 326 13 : : : cord-354133-11b0d499 327 1 Preliminary preliminary JJ cord-354133-11b0d499 327 2 results result NNS cord-354133-11b0d499 327 3 from from IN cord-354133-11b0d499 327 4 a a DT cord-354133-11b0d499 327 5 mass mass JJ cord-354133-11b0d499 327 6 population population NN cord-354133-11b0d499 327 7 screening screen VBG cord-354133-11b0d499 327 8 Australian australian JJ cord-354133-11b0d499 327 9 Government Government NNP cord-354133-11b0d499 327 10 : : : cord-354133-11b0d499 327 11 Department Department NNP cord-354133-11b0d499 327 12 of of IN cord-354133-11b0d499 327 13 Health Health NNP cord-354133-11b0d499 327 14 . . . cord-354133-11b0d499 328 1 Coronavirus Coronavirus NNP cord-354133-11b0d499 328 2 ( ( -LRB- cord-354133-11b0d499 328 3 COVID-19 covid-19 VB cord-354133-11b0d499 328 4 ) ) -RRB- cord-354133-11b0d499 328 5 current current JJ cord-354133-11b0d499 328 6 situation situation NN cord-354133-11b0d499 328 7 and and CC cord-354133-11b0d499 328 8 case case NN cord-354133-11b0d499 328 9 numbers number NNS cord-354133-11b0d499 328 10 Assessing assess VBG cord-354133-11b0d499 328 11 the the DT cord-354133-11b0d499 328 12 Age Age NNP cord-354133-11b0d499 328 13 Specificity Specificity NNP cord-354133-11b0d499 328 14 of of IN cord-354133-11b0d499 328 15 Infection Infection NNP cord-354133-11b0d499 328 16 Fatality Fatality NNP cord-354133-11b0d499 328 17 Rates Rates NNPS cord-354133-11b0d499 328 18 for for IN cord-354133-11b0d499 328 19 COVID-19 covid-19 NN cord-354133-11b0d499 328 20 : : : cord-354133-11b0d499 329 1 Meta Meta NNP cord-354133-11b0d499 329 2 - - HYPH cord-354133-11b0d499 329 3 Analysis Analysis NNP cord-354133-11b0d499 329 4 & & CC cord-354133-11b0d499 329 5 Public Public NNP cord-354133-11b0d499 329 6 Policy Policy NNP cord-354133-11b0d499 329 7 Implications Implications NNPS cord-354133-11b0d499 329 8 Determinants determinant NNS cord-354133-11b0d499 329 9 of of IN cord-354133-11b0d499 329 10 the the DT cord-354133-11b0d499 329 11 Number Number NNP cord-354133-11b0d499 329 12 of of IN cord-354133-11b0d499 329 13 Deaths Deaths NNPS cord-354133-11b0d499 329 14 from from IN cord-354133-11b0d499 329 15 COVID-19 covid-19 NN cord-354133-11b0d499 329 16 : : : cord-354133-11b0d499 329 17 Differences difference NNS cord-354133-11b0d499 329 18 between between IN cord-354133-11b0d499 329 19 Low Low NNP cord-354133-11b0d499 329 20 - - HYPH cord-354133-11b0d499 329 21 Income Income NNP cord-354133-11b0d499 329 22 and and CC cord-354133-11b0d499 329 23 High High NNP cord-354133-11b0d499 329 24 - - HYPH cord-354133-11b0d499 329 25 Income Income NNP cord-354133-11b0d499 329 26 Countries Countries NNPS cord-354133-11b0d499 329 27 in in IN cord-354133-11b0d499 329 28 the the DT cord-354133-11b0d499 329 29 Initial Initial NNP cord-354133-11b0d499 329 30 Stages Stages NNPS cord-354133-11b0d499 329 31 of of IN cord-354133-11b0d499 329 32 the the DT cord-354133-11b0d499 329 33 Pandemic Pandemic NNP cord-354133-11b0d499 329 34 Targets Targets NNPS cord-354133-11b0d499 329 35 of of IN cord-354133-11b0d499 329 36 T T NNP cord-354133-11b0d499 329 37 cell cell NN cord-354133-11b0d499 329 38 responses response NNS cord-354133-11b0d499 329 39 to to IN cord-354133-11b0d499 329 40 SARS SARS NNP cord-354133-11b0d499 329 41 - - HYPH cord-354133-11b0d499 329 42 CoV-2 CoV-2 NNP cord-354133-11b0d499 329 43 coronavirus coronavirus NN cord-354133-11b0d499 329 44 in in IN cord-354133-11b0d499 329 45 humans human NNS cord-354133-11b0d499 329 46 with with IN cord-354133-11b0d499 329 47 COVID-19 COVID-19 NNP cord-354133-11b0d499 329 48 disease disease NN cord-354133-11b0d499 329 49 and and CC cord-354133-11b0d499 329 50 unexposed unexposed JJ cord-354133-11b0d499 329 51 individuals individual NNS cord-354133-11b0d499 330 1 We -PRON- PRP cord-354133-11b0d499 330 2 thank thank VBP cord-354133-11b0d499 330 3 Dr Dr NNP cord-354133-11b0d499 330 4 Nick Nick NNP cord-354133-11b0d499 330 5 Golding Golding NNP cord-354133-11b0d499 330 6 ( ( -LRB- cord-354133-11b0d499 330 7 Curtin Curtin NNP cord-354133-11b0d499 330 8 University University NNP cord-354133-11b0d499 330 9 ) ) -RRB- cord-354133-11b0d499 330 10 for for IN cord-354133-11b0d499 330 11 many many JJ cord-354133-11b0d499 330 12 helpful helpful JJ cord-354133-11b0d499 330 13 conversations conversation NNS cord-354133-11b0d499 330 14 and and CC cord-354133-11b0d499 330 15 comments comment NNS cord-354133-11b0d499 330 16 on on IN cord-354133-11b0d499 330 17 the the DT cord-354133-11b0d499 330 18 manuscript manuscript NN cord-354133-11b0d499 330 19 . . . cord-354133-11b0d499 331 1 The the DT cord-354133-11b0d499 331 2 data datum NNS cord-354133-11b0d499 331 3 used use VBD cord-354133-11b0d499 331 4 this this DT cord-354133-11b0d499 331 5 study study NN cord-354133-11b0d499 331 6 are be VBP cord-354133-11b0d499 331 7 publicly publicly RB cord-354133-11b0d499 331 8 available available JJ cord-354133-11b0d499 331 9 . . . cord-354133-11b0d499 332 1 COVID-19 COVID-19 NNP cord-354133-11b0d499 332 2 data datum NNS cord-354133-11b0d499 332 3 are be VBP cord-354133-11b0d499 332 4 from from IN cord-354133-11b0d499 332 5 the the DT cord-354133-11b0d499 332 6 COVID-19 COVID-19 NNP cord-354133-11b0d499 332 7 Data Data NNP cord-354133-11b0d499 332 8 _SP cord-354133-11b0d499 333 1 It -PRON- PRP cord-354133-11b0d499 333 2 is be VBZ cord-354133-11b0d499 333 3 made make VBN cord-354133-11b0d499 333 4 available available JJ cord-354133-11b0d499 333 5 under under IN cord-354133-11b0d499 333 6 a a DT cord-354133-11b0d499 333 7 perpetuity.is perpetuity.is NN cord-354133-11b0d499 334 1 the the DT cord-354133-11b0d499 334 2 author author NN cord-354133-11b0d499 334 3 / / SYM cord-354133-11b0d499 334 4 funder funder NN cord-354133-11b0d499 334 5 , , , cord-354133-11b0d499 334 6 who who WP cord-354133-11b0d499 334 7 has have VBZ cord-354133-11b0d499 334 8 granted grant VBN cord-354133-11b0d499 334 9 medRxiv medRxiv NNS cord-354133-11b0d499 334 10 a a DT cord-354133-11b0d499 334 11 license license NN cord-354133-11b0d499 334 12 to to TO cord-354133-11b0d499 334 13 display display VB cord-354133-11b0d499 334 14 the the DT cord-354133-11b0d499 334 15 preprint preprint NN cord-354133-11b0d499 334 16 in in IN cord-354133-11b0d499 334 17 ( ( -LRB- cord-354133-11b0d499 334 18 which which WDT cord-354133-11b0d499 334 19 was be VBD cord-354133-11b0d499 334 20 not not RB cord-354133-11b0d499 334 21 certified certify VBN cord-354133-11b0d499 334 22 by by IN cord-354133-11b0d499 334 23 peer peer NN cord-354133-11b0d499 334 24 review review NN cord-354133-11b0d499 334 25 ) ) -RRB- cord-354133-11b0d499 335 1 preprintThe preprintThe NNP cord-354133-11b0d499 335 2 copyright copyright NN cord-354133-11b0d499 335 3 holder holder NN cord-354133-11b0d499 335 4 for for IN cord-354133-11b0d499 335 5 this this DT cord-354133-11b0d499 335 6 this this DT cord-354133-11b0d499 335 7 version version NN cord-354133-11b0d499 335 8 posted post VBD cord-354133-11b0d499 335 9 October October NNP cord-354133-11b0d499 335 10 27 27 CD cord-354133-11b0d499 335 11 , , , cord-354133-11b0d499 335 12 2020 2020 CD cord-354133-11b0d499 335 13 . . . cord-354133-11b0d499 336 1 ; ; : cord-354133-11b0d499 336 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 336 3 doi doi NN cord-354133-11b0d499 336 4 : : : cord-354133-11b0d499 336 5 medRxiv medRxiv NNS cord-354133-11b0d499 336 6 preprint preprint NN cord-354133-11b0d499 336 7 It -PRON- PRP cord-354133-11b0d499 336 8 is be VBZ cord-354133-11b0d499 336 9 made make VBN cord-354133-11b0d499 336 10 available available JJ cord-354133-11b0d499 336 11 under under IN cord-354133-11b0d499 336 12 a a DT cord-354133-11b0d499 336 13 perpetuity.is perpetuity.is NN cord-354133-11b0d499 337 1 the the DT cord-354133-11b0d499 337 2 author author NN cord-354133-11b0d499 337 3 / / SYM cord-354133-11b0d499 337 4 funder funder NN cord-354133-11b0d499 337 5 , , , cord-354133-11b0d499 337 6 who who WP cord-354133-11b0d499 337 7 has have VBZ cord-354133-11b0d499 337 8 granted grant VBN cord-354133-11b0d499 337 9 medRxiv medRxiv NNS cord-354133-11b0d499 337 10 a a DT cord-354133-11b0d499 337 11 license license NN cord-354133-11b0d499 337 12 to to TO cord-354133-11b0d499 337 13 display display VB cord-354133-11b0d499 337 14 the the DT cord-354133-11b0d499 337 15 preprint preprint NN cord-354133-11b0d499 337 16 in in IN cord-354133-11b0d499 337 17 ( ( -LRB- cord-354133-11b0d499 337 18 which which WDT cord-354133-11b0d499 337 19 was be VBD cord-354133-11b0d499 337 20 not not RB cord-354133-11b0d499 337 21 certified certify VBN cord-354133-11b0d499 337 22 by by IN cord-354133-11b0d499 337 23 peer peer NN cord-354133-11b0d499 337 24 review review NN cord-354133-11b0d499 337 25 ) ) -RRB- cord-354133-11b0d499 338 1 preprintThe preprintThe NNP cord-354133-11b0d499 338 2 copyright copyright NN cord-354133-11b0d499 338 3 holder holder NN cord-354133-11b0d499 338 4 for for IN cord-354133-11b0d499 338 5 this this DT cord-354133-11b0d499 338 6 this this DT cord-354133-11b0d499 338 7 version version NN cord-354133-11b0d499 338 8 posted post VBD cord-354133-11b0d499 338 9 October October NNP cord-354133-11b0d499 338 10 27 27 CD cord-354133-11b0d499 338 11 , , , cord-354133-11b0d499 338 12 2020 2020 CD cord-354133-11b0d499 338 13 . . . cord-354133-11b0d499 339 1 ; ; : cord-354133-11b0d499 339 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 339 3 doi doi NN cord-354133-11b0d499 339 4 : : : cord-354133-11b0d499 339 5 medRxiv medRxiv NNS cord-354133-11b0d499 339 6 preprint preprint NN cord-354133-11b0d499 339 7 It -PRON- PRP cord-354133-11b0d499 339 8 is be VBZ cord-354133-11b0d499 339 9 made make VBN cord-354133-11b0d499 339 10 available available JJ cord-354133-11b0d499 339 11 under under IN cord-354133-11b0d499 339 12 a a DT cord-354133-11b0d499 339 13 perpetuity.is perpetuity.is NN cord-354133-11b0d499 340 1 the the DT cord-354133-11b0d499 340 2 author author NN cord-354133-11b0d499 340 3 / / SYM cord-354133-11b0d499 340 4 funder funder NN cord-354133-11b0d499 340 5 , , , cord-354133-11b0d499 340 6 who who WP cord-354133-11b0d499 340 7 has have VBZ cord-354133-11b0d499 340 8 granted grant VBN cord-354133-11b0d499 340 9 medRxiv medRxiv NNS cord-354133-11b0d499 340 10 a a DT cord-354133-11b0d499 340 11 license license NN cord-354133-11b0d499 340 12 to to TO cord-354133-11b0d499 340 13 display display VB cord-354133-11b0d499 340 14 the the DT cord-354133-11b0d499 340 15 preprint preprint NN cord-354133-11b0d499 340 16 in in IN cord-354133-11b0d499 340 17 ( ( -LRB- cord-354133-11b0d499 340 18 which which WDT cord-354133-11b0d499 340 19 was be VBD cord-354133-11b0d499 340 20 not not RB cord-354133-11b0d499 340 21 certified certify VBN cord-354133-11b0d499 340 22 by by IN cord-354133-11b0d499 340 23 peer peer NN cord-354133-11b0d499 340 24 review review NN cord-354133-11b0d499 340 25 ) ) -RRB- cord-354133-11b0d499 341 1 preprintThe preprintThe NNP cord-354133-11b0d499 341 2 copyright copyright NN cord-354133-11b0d499 341 3 holder holder NN cord-354133-11b0d499 341 4 for for IN cord-354133-11b0d499 341 5 this this DT cord-354133-11b0d499 341 6 this this DT cord-354133-11b0d499 341 7 version version NN cord-354133-11b0d499 341 8 posted post VBD cord-354133-11b0d499 341 9 October October NNP cord-354133-11b0d499 341 10 27 27 CD cord-354133-11b0d499 341 11 , , , cord-354133-11b0d499 341 12 2020 2020 CD cord-354133-11b0d499 341 13 . . . cord-354133-11b0d499 342 1 ; ; : cord-354133-11b0d499 342 2 https://doi.org/10.1101/2020.10.25.20216671 https://doi.org/10.1101/2020.10.25.20216671 NN cord-354133-11b0d499 342 3 doi doi NN cord-354133-11b0d499 342 4 : : : cord-354133-11b0d499 343 1 medRxiv medRxiv NNP cord-354133-11b0d499 343 2 preprint preprint NNP