id	sid	tid	token	lemma	pos
cord-291400-o9skj94r	1	1	key	key	NN
cord-291400-o9skj94r	1	2	:	:	:
cord-291400-o9skj94r	2	1	cord-291400-o9skj94r	cord-291400-o9skj94r	JJ
cord-291400-o9skj94r	2	2	authors	author	NNS
cord-291400-o9skj94r	2	3	:	:	:
cord-291400-o9skj94r	2	4	Plouffe	Plouffe	NNP
cord-291400-o9skj94r	2	5	,	,	,
cord-291400-o9skj94r	2	6	Joseph	Joseph	NNP
cord-291400-o9skj94r	2	7	F.	F.	NNP
cord-291400-o9skj94r	2	8	;	;	:
cord-291400-o9skj94r	2	9	Martin	Martin	NNP
cord-291400-o9skj94r	2	10	,	,	,
cord-291400-o9skj94r	2	11	Daniel	Daniel	NNP
cord-291400-o9skj94r	2	12	R.	R.	NNP
cord-291400-o9skj94r	2	13	title	title	NN
cord-291400-o9skj94r	2	14	:	:	:
cord-291400-o9skj94r	2	15	Re	re	NN
cord-291400-o9skj94r	2	16	-	-	NN
cord-291400-o9skj94r	2	17	evaluation	evaluation	NN
cord-291400-o9skj94r	2	18	of	of	IN
cord-291400-o9skj94r	2	19	the	the	DT
cord-291400-o9skj94r	2	20	therapy	therapy	NN
cord-291400-o9skj94r	2	21	of	of	IN
cord-291400-o9skj94r	2	22	severe	severe	JJ
cord-291400-o9skj94r	2	23	pneumonia	pneumonia	NN
cord-291400-o9skj94r	2	24	caused	cause	VBN
cord-291400-o9skj94r	2	25	by	by	IN
cord-291400-o9skj94r	2	26	Streptococcus	Streptococcus	NNP
cord-291400-o9skj94r	2	27	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	2	28	date	date	NN
cord-291400-o9skj94r	2	29	:	:	:
cord-291400-o9skj94r	2	30	2004	2004	CD
cord-291400-o9skj94r	2	31	-	-	SYM
cord-291400-o9skj94r	2	32	12	12	CD
cord-291400-o9skj94r	2	33	-	-	SYM
cord-291400-o9skj94r	2	34	31	31	CD
cord-291400-o9skj94r	2	35	journal	journal	NN
cord-291400-o9skj94r	2	36	:	:	:
cord-291400-o9skj94r	3	1	Infectious	Infectious	NNP
cord-291400-o9skj94r	3	2	Disease	Disease	NNP
cord-291400-o9skj94r	3	3	Clinics	Clinics	NNPS
cord-291400-o9skj94r	3	4	of	of	IN
cord-291400-o9skj94r	3	5	North	North	NNP
cord-291400-o9skj94r	3	6	America	America	NNP
cord-291400-o9skj94r	4	1	DOI	DOI	NNP
cord-291400-o9skj94r	4	2	:	:	:
cord-291400-o9skj94r	5	1	10.1016	10.1016	CD
cord-291400-o9skj94r	5	2	/	/	SYM
cord-291400-o9skj94r	5	3	j.idc.2004.07.010	j.idc.2004.07.010	NNP
cord-291400-o9skj94r	5	4	sha	sha	NNP
cord-291400-o9skj94r	5	5	:	:	:
cord-291400-o9skj94r	5	6	78ca56539d91241980834ef161d5d111e58c5e0d	78ca56539d91241980834ef161d5d111e58c5e0d	CD
cord-291400-o9skj94r	5	7	doc_id	doc_id	CD
cord-291400-o9skj94r	5	8	:	:	:
cord-291400-o9skj94r	5	9	291400	291400	CD
cord-291400-o9skj94r	5	10	cord_uid	cord_uid	NNS
cord-291400-o9skj94r	5	11	:	:	:
cord-291400-o9skj94r	6	1	o9skj94r	o9skj94r	NNP
cord-291400-o9skj94r	6	2	Pneumonia	Pneumonia	NNP
cord-291400-o9skj94r	6	3	caused	cause	VBN
cord-291400-o9skj94r	6	4	by	by	IN
cord-291400-o9skj94r	6	5	Streptococcus	Streptococcus	NNP
cord-291400-o9skj94r	6	6	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	6	7	is	be	VBZ
cord-291400-o9skj94r	6	8	the	the	DT
cord-291400-o9skj94r	6	9	most	most	RBS
cord-291400-o9skj94r	6	10	deadly	deadly	JJ
cord-291400-o9skj94r	6	11	form	form	NN
cord-291400-o9skj94r	6	12	of	of	IN
cord-291400-o9skj94r	6	13	community	community	NN
cord-291400-o9skj94r	6	14	-	-	HYPH
cord-291400-o9skj94r	6	15	acquired	acquire	VBN
cord-291400-o9skj94r	6	16	pneumonia	pneumonia	NN
cord-291400-o9skj94r	6	17	.	.	.
cord-291400-o9skj94r	7	1	The	the	DT
cord-291400-o9skj94r	7	2	death	death	NN
cord-291400-o9skj94r	7	3	rate	rate	NN
cord-291400-o9skj94r	7	4	of	of	IN
cord-291400-o9skj94r	7	5	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	7	6	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	7	7	pneumonia	pneumonia	NN
cord-291400-o9skj94r	7	8	has	have	VBZ
cord-291400-o9skj94r	7	9	remained	remain	VBN
cord-291400-o9skj94r	7	10	constant	constant	JJ
cord-291400-o9skj94r	7	11	over	over	IN
cord-291400-o9skj94r	7	12	the	the	DT
cord-291400-o9skj94r	7	13	past	past	JJ
cord-291400-o9skj94r	7	14	50	50	CD
cord-291400-o9skj94r	7	15	years	year	NNS
cord-291400-o9skj94r	7	16	.	.	.
cord-291400-o9skj94r	8	1	Several	several	JJ
cord-291400-o9skj94r	8	2	retrospective	retrospective	JJ
cord-291400-o9skj94r	8	3	reviews	review	NNS
cord-291400-o9skj94r	8	4	of	of	IN
cord-291400-o9skj94r	8	5	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	8	6	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	8	7	pneumonia	pneumonia	NN
cord-291400-o9skj94r	8	8	suggest	suggest	VBP
cord-291400-o9skj94r	8	9	that	that	IN
cord-291400-o9skj94r	8	10	dual	dual	JJ
cord-291400-o9skj94r	8	11	therapy	therapy	NN
cord-291400-o9skj94r	8	12	with	with	IN
cord-291400-o9skj94r	8	13	a	a	DT
cord-291400-o9skj94r	8	14	beta	beta	NN
cord-291400-o9skj94r	8	15	-	-	HYPH
cord-291400-o9skj94r	8	16	lactam	lactam	NNS
cord-291400-o9skj94r	8	17	and	and	CC
cord-291400-o9skj94r	8	18	a	a	DT
cord-291400-o9skj94r	8	19	macrolide	macrolide	JJ
cord-291400-o9skj94r	8	20	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	8	21	agent	agent	NN
cord-291400-o9skj94r	8	22	is	be	VBZ
cord-291400-o9skj94r	8	23	associated	associate	VBN
cord-291400-o9skj94r	8	24	with	with	IN
cord-291400-o9skj94r	8	25	a	a	DT
cord-291400-o9skj94r	8	26	lower	low	JJR
cord-291400-o9skj94r	8	27	case	case	NN
cord-291400-o9skj94r	8	28	fatality	fatality	NN
cord-291400-o9skj94r	8	29	rate	rate	NN
cord-291400-o9skj94r	8	30	than	than	IN
cord-291400-o9skj94r	8	31	therapy	therapy	NN
cord-291400-o9skj94r	8	32	with	with	IN
cord-291400-o9skj94r	8	33	a	a	DT
cord-291400-o9skj94r	8	34	beta	beta	NN
cord-291400-o9skj94r	8	35	-	-	HYPH
cord-291400-o9skj94r	8	36	lactam	lactam	NN
cord-291400-o9skj94r	8	37	alone	alone	RB
cord-291400-o9skj94r	8	38	.	.	.
cord-291400-o9skj94r	9	1	These	these	DT
cord-291400-o9skj94r	9	2	studies	study	NNS
cord-291400-o9skj94r	9	3	are	be	VBP
cord-291400-o9skj94r	9	4	reviewed	review	VBN
cord-291400-o9skj94r	9	5	,	,	,
cord-291400-o9skj94r	9	6	potential	potential	JJ
cord-291400-o9skj94r	9	7	mechanisms	mechanism	NNS
cord-291400-o9skj94r	9	8	are	be	VBP
cord-291400-o9skj94r	9	9	suggested	suggest	VBN
cord-291400-o9skj94r	9	10	,	,	,
cord-291400-o9skj94r	9	11	and	and	CC
cord-291400-o9skj94r	9	12	future	future	JJ
cord-291400-o9skj94r	9	13	studies	study	NNS
cord-291400-o9skj94r	9	14	are	be	VBP
cord-291400-o9skj94r	9	15	discussed	discuss	VBN
cord-291400-o9skj94r	9	16	.	.	.
cord-291400-o9skj94r	10	1	With	with	IN
cord-291400-o9skj94r	10	2	the	the	DT
cord-291400-o9skj94r	10	3	advent	advent	NN
cord-291400-o9skj94r	10	4	of	of	IN
cord-291400-o9skj94r	10	5	modern	modern	JJ
cord-291400-o9skj94r	10	6	microbiology	microbiology	NN
cord-291400-o9skj94r	10	7	,	,	,
cord-291400-o9skj94r	10	8	Streptococcus	streptococcus	NN
cord-291400-o9skj94r	10	9	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	10	10	(	(	-LRB-
cord-291400-o9skj94r	10	11	pneumococcus	pneumococcus	NNP
cord-291400-o9skj94r	10	12	)	)	-RRB-
cord-291400-o9skj94r	10	13	was	be	VBD
cord-291400-o9skj94r	10	14	identified	identify	VBN
cord-291400-o9skj94r	10	15	as	as	IN
cord-291400-o9skj94r	10	16	the	the	DT
cord-291400-o9skj94r	10	17	cause	cause	NN
cord-291400-o9skj94r	10	18	of	of	IN
cord-291400-o9skj94r	10	19	community	community	NN
cord-291400-o9skj94r	10	20	-	-	HYPH
cord-291400-o9skj94r	10	21	acquired	acquire	VBN
cord-291400-o9skj94r	10	22	pneumonia	pneumonia	NN
cord-291400-o9skj94r	10	23	(	(	-LRB-
cord-291400-o9skj94r	10	24	CAP	CAP	NNP
cord-291400-o9skj94r	10	25	)	)	-RRB-
cord-291400-o9skj94r	10	26	in	in	IN
cord-291400-o9skj94r	10	27	the	the	DT
cord-291400-o9skj94r	10	28	most	most	JJS
cord-291400-o9skj94r	10	29	patients	patient	NNS
cord-291400-o9skj94r	10	30	[	[	-LRB-
cord-291400-o9skj94r	10	31	1	1	CD
cord-291400-o9skj94r	10	32	]	]	-RRB-
cord-291400-o9skj94r	10	33	.	.	.
cord-291400-o9skj94r	11	1	The	the	DT
cord-291400-o9skj94r	11	2	case	case	NN
cord-291400-o9skj94r	11	3	fatality	fatality	NN
cord-291400-o9skj94r	11	4	rate	rate	NN
cord-291400-o9skj94r	11	5	(	(	-LRB-
cord-291400-o9skj94r	11	6	CFR	CFR	NNP
cord-291400-o9skj94r	11	7	)	)	-RRB-
cord-291400-o9skj94r	11	8	of	of	IN
cord-291400-o9skj94r	11	9	untreated	untreated	JJ
cord-291400-o9skj94r	11	10	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	11	11	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	11	12	pneumonia	pneumonia	NN
cord-291400-o9skj94r	11	13	was	be	VBD
cord-291400-o9skj94r	11	14	80	80	CD
cord-291400-o9skj94r	11	15	%	%	NN
cord-291400-o9skj94r	11	16	.	.	.
cord-291400-o9skj94r	12	1	Early	early	JJ
cord-291400-o9skj94r	12	2	studies	study	NNS
cord-291400-o9skj94r	12	3	defined	define	VBD
cord-291400-o9skj94r	12	4	the	the	DT
cord-291400-o9skj94r	12	5	importance	importance	NN
cord-291400-o9skj94r	12	6	of	of	IN
cord-291400-o9skj94r	12	7	opsonizing	opsonize	VBG
cord-291400-o9skj94r	12	8	antibodies	antibody	NNS
cord-291400-o9skj94r	12	9	to	to	IN
cord-291400-o9skj94r	12	10	the	the	DT
cord-291400-o9skj94r	12	11	infecting	infect	VBG
cord-291400-o9skj94r	12	12	serotype	serotype	NN
cord-291400-o9skj94r	12	13	.	.	.
cord-291400-o9skj94r	13	1	Serum	serum	NN
cord-291400-o9skj94r	13	2	therapy	therapy	NN
cord-291400-o9skj94r	13	3	was	be	VBD
cord-291400-o9skj94r	13	4	instituted	institute	VBN
cord-291400-o9skj94r	13	5	in	in	IN
cord-291400-o9skj94r	13	6	the	the	DT
cord-291400-o9skj94r	13	7	1930s	1930	NNS
cord-291400-o9skj94r	13	8	and	and	CC
cord-291400-o9skj94r	13	9	resulted	result	VBD
cord-291400-o9skj94r	13	10	in	in	IN
cord-291400-o9skj94r	13	11	the	the	DT
cord-291400-o9skj94r	13	12	decrease	decrease	NN
cord-291400-o9skj94r	13	13	of	of	IN
cord-291400-o9skj94r	13	14	the	the	DT
cord-291400-o9skj94r	13	15	CFR	CFR	NNP
cord-291400-o9skj94r	13	16	to	to	IN
cord-291400-o9skj94r	13	17	50	50	CD
cord-291400-o9skj94r	13	18	%	%	NN
cord-291400-o9skj94r	13	19	.	.	.
cord-291400-o9skj94r	14	1	With	with	IN
cord-291400-o9skj94r	14	2	the	the	DT
cord-291400-o9skj94r	14	3	advent	advent	NN
cord-291400-o9skj94r	14	4	of	of	IN
cord-291400-o9skj94r	14	5	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	14	6	therapy	therapy	NN
cord-291400-o9skj94r	14	7	in	in	IN
cord-291400-o9skj94r	14	8	the	the	DT
cord-291400-o9skj94r	14	9	1940s	1940	NNS
cord-291400-o9skj94r	14	10	,	,	,
cord-291400-o9skj94r	14	11	the	the	DT
cord-291400-o9skj94r	14	12	CFR	CFR	NNP
cord-291400-o9skj94r	14	13	of	of	IN
cord-291400-o9skj94r	14	14	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	14	15	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	14	16	disease	disease	NN
cord-291400-o9skj94r	14	17	was	be	VBD
cord-291400-o9skj94r	14	18	decreased	decrease	VBN
cord-291400-o9skj94r	14	19	further	further	RB
cord-291400-o9skj94r	14	20	to	to	IN
cord-291400-o9skj94r	14	21	20	20	CD
cord-291400-o9skj94r	14	22	%	%	NN
cord-291400-o9skj94r	14	23	.	.	.
cord-291400-o9skj94r	15	1	The	the	DT
cord-291400-o9skj94r	15	2	changing	change	VBG
cord-291400-o9skj94r	15	3	pattern	pattern	NN
cord-291400-o9skj94r	15	4	of	of	IN
cord-291400-o9skj94r	15	5	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	15	6	pneumonia	pneumonia	NN
cord-291400-o9skj94r	15	7	was	be	VBD
cord-291400-o9skj94r	15	8	recognized	recognize	VBN
cord-291400-o9skj94r	15	9	[	[	-LRB-
cord-291400-o9skj94r	15	10	2	2	CD
cord-291400-o9skj94r	15	11	]	]	-RRB-
cord-291400-o9skj94r	15	12	.	.	.
cord-291400-o9skj94r	16	1	Over	over	IN
cord-291400-o9skj94r	16	2	the	the	DT
cord-291400-o9skj94r	16	3	next	next	JJ
cord-291400-o9skj94r	16	4	50	50	CD
cord-291400-o9skj94r	16	5	years	year	NNS
cord-291400-o9skj94r	16	6	,	,	,
cord-291400-o9skj94r	16	7	even	even	RB
cord-291400-o9skj94r	16	8	though	though	IN
cord-291400-o9skj94r	16	9	the	the	DT
cord-291400-o9skj94r	16	10	pneumococcus	pneumococcus	NN
cord-291400-o9skj94r	16	11	remained	remain	VBD
cord-291400-o9skj94r	16	12	susceptible	susceptible	JJ
cord-291400-o9skj94r	16	13	to	to	IN
cord-291400-o9skj94r	16	14	penicillin	penicillin	NN
cord-291400-o9skj94r	16	15	,	,	,
cord-291400-o9skj94r	16	16	the	the	DT
cord-291400-o9skj94r	16	17	CFR	CFR	NNP
cord-291400-o9skj94r	16	18	remained	remain	VBD
cord-291400-o9skj94r	16	19	constant	constant	JJ
cord-291400-o9skj94r	16	20	.	.	.
cord-291400-o9skj94r	17	1	Modern	modern	JJ
cord-291400-o9skj94r	17	2	ICUs	icu	NNS
cord-291400-o9skj94r	17	3	failed	fail	VBD
cord-291400-o9skj94r	17	4	to	to	TO
cord-291400-o9skj94r	17	5	improve	improve	VB
cord-291400-o9skj94r	17	6	on	on	IN
cord-291400-o9skj94r	17	7	the	the	DT
cord-291400-o9skj94r	17	8	20	20	CD
cord-291400-o9skj94r	17	9	%	%	NN
cord-291400-o9skj94r	17	10	CFR	CFR	NNP
cord-291400-o9skj94r	17	11	[	[	-LRB-
cord-291400-o9skj94r	17	12	3	3	CD
cord-291400-o9skj94r	17	13	]	]	-RRB-
cord-291400-o9skj94r	17	14	.	.	.
cord-291400-o9skj94r	18	1	To	to	TO
cord-291400-o9skj94r	18	2	further	further	RB
cord-291400-o9skj94r	18	3	complicate	complicate	VB
cord-291400-o9skj94r	18	4	matters	matter	NNS
cord-291400-o9skj94r	18	5	,	,	,
cord-291400-o9skj94r	18	6	in	in	IN
cord-291400-o9skj94r	18	7	the	the	DT
cord-291400-o9skj94r	18	8	1990s	1990	NNS
cord-291400-o9skj94r	18	9	,	,	,
cord-291400-o9skj94r	18	10	some	some	DT
cord-291400-o9skj94r	18	11	S	S	NNP
cord-291400-o9skj94r	18	12	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	18	13	strains	strain	NNS
cord-291400-o9skj94r	18	14	developed	develop	VBD
cord-291400-o9skj94r	18	15	resistance	resistance	NN
cord-291400-o9skj94r	18	16	to	to	IN
cord-291400-o9skj94r	18	17	penicillin	penicillin	NN
cord-291400-o9skj94r	18	18	and	and	CC
cord-291400-o9skj94r	18	19	other	other	JJ
cord-291400-o9skj94r	18	20	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	18	21	agents	agent	NNS
cord-291400-o9skj94r	18	22	used	use	VBN
cord-291400-o9skj94r	18	23	to	to	TO
cord-291400-o9skj94r	18	24	treat	treat	VB
cord-291400-o9skj94r	18	25	pneumonia	pneumonia	NN
cord-291400-o9skj94r	18	26	[	[	-LRB-
cord-291400-o9skj94r	18	27	4	4	CD
cord-291400-o9skj94r	18	28	]	]	-RRB-
cord-291400-o9skj94r	18	29	.	.	.
cord-291400-o9skj94r	19	1	Several	several	JJ
cord-291400-o9skj94r	19	2	retrospective	retrospective	JJ
cord-291400-o9skj94r	19	3	studies	study	NNS
cord-291400-o9skj94r	19	4	have	have	VBP
cord-291400-o9skj94r	19	5	suggested	suggest	VBN
cord-291400-o9skj94r	19	6	that	that	IN
cord-291400-o9skj94r	19	7	combination	combination	NN
cord-291400-o9skj94r	19	8	therapy	therapy	NN
cord-291400-o9skj94r	19	9	with	with	IN
cord-291400-o9skj94r	19	10	a	a	DT
cord-291400-o9skj94r	19	11	b	b	NN
cord-291400-o9skj94r	19	12	-	-	HYPH
cord-291400-o9skj94r	19	13	lactam	lactam	NN
cord-291400-o9skj94r	19	14	and	and	CC
cord-291400-o9skj94r	19	15	a	a	DT
cord-291400-o9skj94r	19	16	macrolide	macrolide	JJ
cord-291400-o9skj94r	19	17	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	19	18	agent	agent	NN
cord-291400-o9skj94r	19	19	results	result	VBZ
cord-291400-o9skj94r	19	20	in	in	IN
cord-291400-o9skj94r	19	21	a	a	DT
cord-291400-o9skj94r	19	22	lower	low	JJR
cord-291400-o9skj94r	19	23	CFR	CFR	NNP
cord-291400-o9skj94r	19	24	than	than	IN
cord-291400-o9skj94r	19	25	does	do	VBZ
cord-291400-o9skj94r	19	26	therapy	therapy	NN
cord-291400-o9skj94r	19	27	with	with	IN
cord-291400-o9skj94r	19	28	a	a	DT
cord-291400-o9skj94r	19	29	b	b	NN
cord-291400-o9skj94r	19	30	-	-	HYPH
cord-291400-o9skj94r	19	31	lactam	lactam	NN
cord-291400-o9skj94r	19	32	alone	alone	JJ
cord-291400-o9skj94r	19	33	[	[	-LRB-
cord-291400-o9skj94r	19	34	5	5	CD
cord-291400-o9skj94r	19	35	]	]	-RRB-
cord-291400-o9skj94r	19	36	[	[	-LRB-
cord-291400-o9skj94r	19	37	6	6	CD
cord-291400-o9skj94r	19	38	]	]	-RRB-
cord-291400-o9skj94r	19	39	[	[	-LRB-
cord-291400-o9skj94r	19	40	7	7	CD
cord-291400-o9skj94r	19	41	]	]	-RRB-
cord-291400-o9skj94r	19	42	.	.	.
cord-291400-o9skj94r	20	1	This	this	DT
cord-291400-o9skj94r	20	2	article	article	NN
cord-291400-o9skj94r	20	3	addresses	address	VBZ
cord-291400-o9skj94r	20	4	the	the	DT
cord-291400-o9skj94r	20	5	available	available	JJ
cord-291400-o9skj94r	20	6	data	datum	NNS
cord-291400-o9skj94r	20	7	on	on	IN
cord-291400-o9skj94r	20	8	the	the	DT
cord-291400-o9skj94r	20	9	treatment	treatment	NN
cord-291400-o9skj94r	20	10	of	of	IN
cord-291400-o9skj94r	20	11	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	20	12	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	20	13	pneumonia	pneumonia	NN
cord-291400-o9skj94r	20	14	and	and	CC
cord-291400-o9skj94r	20	15	discusses	discuss	VBZ
cord-291400-o9skj94r	20	16	the	the	DT
cord-291400-o9skj94r	20	17	biologically	biologically	RB
cord-291400-o9skj94r	20	18	feasible	feasible	JJ
cord-291400-o9skj94r	20	19	explanations	explanation	NNS
cord-291400-o9skj94r	20	20	behind	behind	IN
cord-291400-o9skj94r	20	21	new	new	JJ
cord-291400-o9skj94r	20	22	therapy	therapy	NN
cord-291400-o9skj94r	20	23	.	.	.
cord-291400-o9skj94r	21	1	Guidelines	guideline	NNS
cord-291400-o9skj94r	21	2	for	for	IN
cord-291400-o9skj94r	21	3	the	the	DT
cord-291400-o9skj94r	21	4	treatment	treatment	NN
cord-291400-o9skj94r	21	5	of	of	IN
cord-291400-o9skj94r	21	6	the	the	DT
cord-291400-o9skj94r	21	7	clinical	clinical	JJ
cord-291400-o9skj94r	21	8	syndrome	syndrome	NN
cord-291400-o9skj94r	21	9	of	of	IN
cord-291400-o9skj94r	21	10	CAP	CAP	NNP
cord-291400-o9skj94r	21	11	have	have	VBP
cord-291400-o9skj94r	21	12	been	be	VBN
cord-291400-o9skj94r	21	13	published	publish	VBN
cord-291400-o9skj94r	21	14	by	by	IN
cord-291400-o9skj94r	21	15	several	several	JJ
cord-291400-o9skj94r	21	16	pulmonary	pulmonary	JJ
cord-291400-o9skj94r	21	17	and	and	CC
cord-291400-o9skj94r	21	18	infectious	infectious	JJ
cord-291400-o9skj94r	21	19	disease	disease	NN
cord-291400-o9skj94r	21	20	societies	society	NNS
cord-291400-o9skj94r	21	21	[	[	-LRB-
cord-291400-o9skj94r	21	22	3	3	CD
cord-291400-o9skj94r	21	23	,	,	,
cord-291400-o9skj94r	21	24	[	[	-LRB-
cord-291400-o9skj94r	21	25	8	8	CD
cord-291400-o9skj94r	21	26	]	]	-RRB-
cord-291400-o9skj94r	21	27	[	[	-LRB-
cord-291400-o9skj94r	21	28	9	9	CD
cord-291400-o9skj94r	21	29	]	]	-RRB-
cord-291400-o9skj94r	21	30	[	[	-LRB-
cord-291400-o9skj94r	21	31	10	10	CD
cord-291400-o9skj94r	21	32	]	]	-RRB-
cord-291400-o9skj94r	21	33	[	[	-LRB-
cord-291400-o9skj94r	21	34	11	11	CD
cord-291400-o9skj94r	21	35	]	]	-RRB-
cord-291400-o9skj94r	21	36	.	.	.
cord-291400-o9skj94r	22	1	These	these	DT
cord-291400-o9skj94r	22	2	guidelines	guideline	NNS
cord-291400-o9skj94r	22	3	are	be	VBP
cord-291400-o9skj94r	22	4	addressed	address	VBN
cord-291400-o9skj94r	22	5	in	in	IN
cord-291400-o9skj94r	22	6	detail	detail	NN
cord-291400-o9skj94r	22	7	in	in	IN
cord-291400-o9skj94r	22	8	other	other	JJ
cord-291400-o9skj94r	22	9	articles	article	NNS
cord-291400-o9skj94r	22	10	in	in	IN
cord-291400-o9skj94r	22	11	this	this	DT
cord-291400-o9skj94r	22	12	issue	issue	NN
cord-291400-o9skj94r	22	13	.	.	.
cord-291400-o9skj94r	23	1	To	to	TO
cord-291400-o9skj94r	23	2	evaluate	evaluate	VB
cord-291400-o9skj94r	23	3	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	23	4	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	23	5	pneumonia	pneumonia	NN
cord-291400-o9skj94r	23	6	,	,	,
cord-291400-o9skj94r	23	7	series	series	NN
cord-291400-o9skj94r	23	8	of	of	IN
cord-291400-o9skj94r	23	9	CAP	cap	NN
cord-291400-o9skj94r	23	10	cases	case	NNS
cord-291400-o9skj94r	23	11	should	should	MD
cord-291400-o9skj94r	23	12	be	be	VB
cord-291400-o9skj94r	23	13	examined	examine	VBN
cord-291400-o9skj94r	23	14	,	,	,
cord-291400-o9skj94r	23	15	as	as	IN
cord-291400-o9skj94r	23	16	physicians	physician	NNS
cord-291400-o9skj94r	23	17	infrequently	infrequently	RB
cord-291400-o9skj94r	23	18	know	know	VBP
cord-291400-o9skj94r	23	19	whether	whether	IN
cord-291400-o9skj94r	23	20	a	a	DT
cord-291400-o9skj94r	23	21	patient	patient	NN
cord-291400-o9skj94r	23	22	has	have	VBZ
cord-291400-o9skj94r	23	23	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	23	24	pneumonia	pneumonia	NN
cord-291400-o9skj94r	23	25	on	on	IN
cord-291400-o9skj94r	23	26	initial	initial	JJ
cord-291400-o9skj94r	23	27	presentation	presentation	NN
cord-291400-o9skj94r	23	28	.	.	.
cord-291400-o9skj94r	24	1	Over	over	IN
cord-291400-o9skj94r	24	2	the	the	DT
cord-291400-o9skj94r	24	3	years	year	NNS
cord-291400-o9skj94r	24	4	,	,	,
cord-291400-o9skj94r	24	5	many	many	JJ
cord-291400-o9skj94r	24	6	series	series	NN
cord-291400-o9skj94r	24	7	of	of	IN
cord-291400-o9skj94r	24	8	CAP	cap	NN
cord-291400-o9skj94r	24	9	cases	case	NNS
cord-291400-o9skj94r	24	10	have	have	VBP
cord-291400-o9skj94r	24	11	been	be	VBN
cord-291400-o9skj94r	24	12	published	publish	VBN
cord-291400-o9skj94r	24	13	and	and	CC
cord-291400-o9skj94r	24	14	reflect	reflect	VB
cord-291400-o9skj94r	24	15	the	the	DT
cord-291400-o9skj94r	24	16	changing	change	VBG
cord-291400-o9skj94r	24	17	nature	nature	NN
cord-291400-o9skj94r	24	18	of	of	IN
cord-291400-o9skj94r	24	19	CAP	cap	NN
cord-291400-o9skj94r	24	20	[	[	-LRB-
cord-291400-o9skj94r	24	21	2	2	CD
cord-291400-o9skj94r	24	22	,	,	,
cord-291400-o9skj94r	24	23	[	[	-LRB-
cord-291400-o9skj94r	24	24	12	12	CD
cord-291400-o9skj94r	24	25	]	]	-RRB-
cord-291400-o9skj94r	24	26	[	[	-LRB-
cord-291400-o9skj94r	24	27	13	13	CD
cord-291400-o9skj94r	24	28	]	]	-RRB-
cord-291400-o9skj94r	24	29	[	[	-LRB-
cord-291400-o9skj94r	24	30	14	14	CD
cord-291400-o9skj94r	24	31	]	]	-RRB-
cord-291400-o9skj94r	24	32	[	[	-LRB-
cord-291400-o9skj94r	24	33	15	15	CD
cord-291400-o9skj94r	24	34	]	]	-RRB-
cord-291400-o9skj94r	24	35	[	[	-LRB-
cord-291400-o9skj94r	24	36	16	16	CD
cord-291400-o9skj94r	24	37	]	]	-RRB-
cord-291400-o9skj94r	24	38	[	[	-LRB-
cord-291400-o9skj94r	24	39	17	17	CD
cord-291400-o9skj94r	24	40	]	]	-RRB-
cord-291400-o9skj94r	24	41	.	.	.
cord-291400-o9skj94r	25	1	In	in	IN
cord-291400-o9skj94r	25	2	series	series	NN
cord-291400-o9skj94r	25	3	of	of	IN
cord-291400-o9skj94r	25	4	CAP	cap	NN
cord-291400-o9skj94r	25	5	through	through	IN
cord-291400-o9skj94r	25	6	the	the	DT
cord-291400-o9skj94r	25	7	1950s	1950	NNS
cord-291400-o9skj94r	25	8	S	S	NNP
cord-291400-o9skj94r	25	9	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	25	10	was	be	VBD
cord-291400-o9skj94r	25	11	the	the	DT
cord-291400-o9skj94r	25	12	predominant	predominant	JJ
cord-291400-o9skj94r	25	13	pathogen	pathogen	NN
cord-291400-o9skj94r	25	14	,	,	,
cord-291400-o9skj94r	25	15	accounting	account	VBG
cord-291400-o9skj94r	25	16	for	for	IN
cord-291400-o9skj94r	25	17	more	more	JJR
cord-291400-o9skj94r	25	18	than	than	IN
cord-291400-o9skj94r	25	19	80	80	CD
cord-291400-o9skj94r	25	20	%	%	NN
cord-291400-o9skj94r	25	21	of	of	IN
cord-291400-o9skj94r	25	22	cases	case	NNS
cord-291400-o9skj94r	25	23	.	.	.
cord-291400-o9skj94r	26	1	In	in	IN
cord-291400-o9skj94r	26	2	each	each	DT
cord-291400-o9skj94r	26	3	subsequent	subsequent	JJ
cord-291400-o9skj94r	26	4	decade	decade	NN
cord-291400-o9skj94r	26	5	,	,	,
cord-291400-o9skj94r	26	6	another	another	DT
cord-291400-o9skj94r	26	7	pathogen	pathogen	NN
cord-291400-o9skj94r	26	8	or	or	CC
cord-291400-o9skj94r	26	9	group	group	NN
cord-291400-o9skj94r	26	10	of	of	IN
cord-291400-o9skj94r	26	11	pathogens	pathogen	NNS
cord-291400-o9skj94r	26	12	has	have	VBZ
cord-291400-o9skj94r	26	13	been	be	VBN
cord-291400-o9skj94r	26	14	identified	identify	VBN
cord-291400-o9skj94r	26	15	as	as	IN
cord-291400-o9skj94r	26	16	causes	cause	NNS
cord-291400-o9skj94r	26	17	of	of	IN
cord-291400-o9skj94r	26	18	CAP	cap	NN
cord-291400-o9skj94r	26	19	.	.	.
cord-291400-o9skj94r	27	1	Mycoplasma	mycoplasma	NN
cord-291400-o9skj94r	27	2	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	27	3	was	be	VBD
cord-291400-o9skj94r	27	4	identified	identify	VBN
cord-291400-o9skj94r	27	5	as	as	IN
cord-291400-o9skj94r	27	6	the	the	DT
cord-291400-o9skj94r	27	7	initial	initial	JJ
cord-291400-o9skj94r	27	8	cause	cause	NN
cord-291400-o9skj94r	27	9	of	of	IN
cord-291400-o9skj94r	27	10	atypical	atypical	JJ
cord-291400-o9skj94r	27	11	pneumonia	pneumonia	NN
cord-291400-o9skj94r	27	12	in	in	IN
cord-291400-o9skj94r	27	13	the	the	DT
cord-291400-o9skj94r	27	14	1960s	1960	NNS
cord-291400-o9skj94r	27	15	.	.	.
cord-291400-o9skj94r	28	1	The	the	DT
cord-291400-o9skj94r	28	2	importance	importance	NN
cord-291400-o9skj94r	28	3	of	of	IN
cord-291400-o9skj94r	28	4	anaerobic	anaerobic	JJ
cord-291400-o9skj94r	28	5	organisms	organism	NNS
cord-291400-o9skj94r	28	6	in	in	IN
cord-291400-o9skj94r	28	7	aspiration	aspiration	NN
cord-291400-o9skj94r	28	8	pneumonia	pneumonia	NN
cord-291400-o9skj94r	28	9	was	be	VBD
cord-291400-o9skj94r	28	10	identified	identify	VBN
cord-291400-o9skj94r	28	11	in	in	IN
cord-291400-o9skj94r	28	12	the	the	DT
cord-291400-o9skj94r	28	13	1970s	1970	NNS
cord-291400-o9skj94r	28	14	.	.	.
cord-291400-o9skj94r	29	1	Legionella	Legionella	NNP
cord-291400-o9skj94r	29	2	pneumophila	pneumophila	NN
cord-291400-o9skj94r	29	3	was	be	VBD
cord-291400-o9skj94r	29	4	discovered	discover	VBN
cord-291400-o9skj94r	29	5	to	to	TO
cord-291400-o9skj94r	29	6	be	be	VB
cord-291400-o9skj94r	29	7	the	the	DT
cord-291400-o9skj94r	29	8	cause	cause	NN
cord-291400-o9skj94r	29	9	of	of	IN
cord-291400-o9skj94r	29	10	the	the	DT
cord-291400-o9skj94r	29	11	epidemic	epidemic	NN
cord-291400-o9skj94r	29	12	of	of	IN
cord-291400-o9skj94r	29	13	Legionnaires	Legionnaires	NNP
cord-291400-o9skj94r	29	14	disease	disease	NN
cord-291400-o9skj94r	29	15	in	in	IN
cord-291400-o9skj94r	29	16	1976	1976	CD
cord-291400-o9skj94r	29	17	.	.	.
cord-291400-o9skj94r	30	1	Chlamydia	Chlamydia	NNP
cord-291400-o9skj94r	30	2	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	30	3	was	be	VBD
cord-291400-o9skj94r	30	4	identified	identify	VBN
cord-291400-o9skj94r	30	5	as	as	IN
cord-291400-o9skj94r	30	6	another	another	DT
cord-291400-o9skj94r	30	7	cause	cause	NN
cord-291400-o9skj94r	30	8	of	of	IN
cord-291400-o9skj94r	30	9	atypical	atypical	JJ
cord-291400-o9skj94r	30	10	pneumonia	pneumonia	NN
cord-291400-o9skj94r	30	11	[	[	-LRB-
cord-291400-o9skj94r	30	12	18	18	CD
cord-291400-o9skj94r	30	13	]	]	-RRB-
cord-291400-o9skj94r	30	14	.	.	.
cord-291400-o9skj94r	31	1	The	the	DT
cord-291400-o9skj94r	31	2	importance	importance	NN
cord-291400-o9skj94r	31	3	of	of	IN
cord-291400-o9skj94r	31	4	atypical	atypical	JJ
cord-291400-o9skj94r	31	5	and	and	CC
cord-291400-o9skj94r	31	6	other	other	JJ
cord-291400-o9skj94r	31	7	viral	viral	JJ
cord-291400-o9skj94r	31	8	causes	cause	NNS
cord-291400-o9skj94r	31	9	of	of	IN
cord-291400-o9skj94r	31	10	CAP	cap	NN
cord-291400-o9skj94r	31	11	in	in	IN
cord-291400-o9skj94r	31	12	adults	adult	NNS
cord-291400-o9skj94r	31	13	(	(	-LRB-
cord-291400-o9skj94r	31	14	ie	ie	NNS
cord-291400-o9skj94r	31	15	,	,	,
cord-291400-o9skj94r	31	16	respiratory	respiratory	JJ
cord-291400-o9skj94r	31	17	syncytial	syncytial	JJ
cord-291400-o9skj94r	31	18	virus	virus	NN
cord-291400-o9skj94r	31	19	,	,	,
cord-291400-o9skj94r	31	20	parainfluenza	parainfluenza	NNP
cord-291400-o9skj94r	31	21	,	,	,
cord-291400-o9skj94r	31	22	hantavirus	hantavirus	NN
cord-291400-o9skj94r	31	23	,	,	,
cord-291400-o9skj94r	31	24	metapneumonia	metapneumonia	NNP
cord-291400-o9skj94r	31	25	virus	virus	NN
cord-291400-o9skj94r	31	26	,	,	,
cord-291400-o9skj94r	31	27	coronavirus	coronavirus	NN
cord-291400-o9skj94r	31	28	[	[	-LRB-
cord-291400-o9skj94r	31	29	severe	severe	JJ
cord-291400-o9skj94r	31	30	acute	acute	JJ
cord-291400-o9skj94r	31	31	respiratory	respiratory	JJ
cord-291400-o9skj94r	31	32	syndrome	syndrome	NN
cord-291400-o9skj94r	31	33	]	]	-RRB-
cord-291400-o9skj94r	31	34	)	)	-RRB-
cord-291400-o9skj94r	31	35	have	have	VBP
cord-291400-o9skj94r	31	36	been	be	VBN
cord-291400-o9skj94r	31	37	identified	identify	VBN
cord-291400-o9skj94r	31	38	by	by	IN
cord-291400-o9skj94r	31	39	various	various	JJ
cord-291400-o9skj94r	31	40	investigators	investigator	NNS
cord-291400-o9skj94r	31	41	,	,	,
cord-291400-o9skj94r	31	42	including	include	VBG
cord-291400-o9skj94r	31	43	those	those	DT
cord-291400-o9skj94r	31	44	at	at	IN
cord-291400-o9skj94r	31	45	the	the	DT
cord-291400-o9skj94r	31	46	Centers	Centers	NNPS
cord-291400-o9skj94r	31	47	for	for	IN
cord-291400-o9skj94r	31	48	Disease	Disease	NNP
cord-291400-o9skj94r	31	49	Control	Control	NNP
cord-291400-o9skj94r	31	50	and	and	CC
cord-291400-o9skj94r	31	51	Prevention	Prevention	NNP
cord-291400-o9skj94r	31	52	and	and	CC
cord-291400-o9skj94r	31	53	World	World	NNP
cord-291400-o9skj94r	31	54	Health	Health	NNP
cord-291400-o9skj94r	31	55	Organization	Organization	NNP
cord-291400-o9skj94r	31	56	[	[	-LRB-
cord-291400-o9skj94r	31	57	19	19	CD
cord-291400-o9skj94r	31	58	]	]	-RRB-
cord-291400-o9skj94r	31	59	[	[	-LRB-
cord-291400-o9skj94r	31	60	20	20	CD
cord-291400-o9skj94r	31	61	]	]	-RRB-
cord-291400-o9skj94r	31	62	[	[	-LRB-
cord-291400-o9skj94r	31	63	21	21	CD
cord-291400-o9skj94r	31	64	]	]	-RRB-
cord-291400-o9skj94r	31	65	[	[	-LRB-
cord-291400-o9skj94r	31	66	22	22	CD
cord-291400-o9skj94r	31	67	]	]	-RRB-
cord-291400-o9skj94r	31	68	[	[	-LRB-
cord-291400-o9skj94r	31	69	23	23	CD
cord-291400-o9skj94r	31	70	]	]	-RRB-
cord-291400-o9skj94r	31	71	.	.	.
cord-291400-o9skj94r	32	1	More	More	JJR
cord-291400-o9skj94r	32	2	recent	recent	JJ
cord-291400-o9skj94r	32	3	series	serie	NNS
cord-291400-o9skj94r	32	4	have	have	VBP
cord-291400-o9skj94r	32	5	been	be	VBN
cord-291400-o9skj94r	32	6	able	able	JJ
cord-291400-o9skj94r	32	7	to	to	TO
cord-291400-o9skj94r	32	8	identify	identify	VB
cord-291400-o9skj94r	32	9	S	S	NNP
cord-291400-o9skj94r	32	10	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	32	11	in	in	IN
cord-291400-o9skj94r	32	12	only	only	RB
cord-291400-o9skj94r	32	13	10	10	CD
cord-291400-o9skj94r	32	14	%	%	NN
cord-291400-o9skj94r	32	15	to	to	IN
cord-291400-o9skj94r	32	16	25	25	CD
cord-291400-o9skj94r	32	17	%	%	NN
cord-291400-o9skj94r	32	18	of	of	IN
cord-291400-o9skj94r	32	19	patients	patient	NNS
cord-291400-o9skj94r	32	20	with	with	IN
cord-291400-o9skj94r	32	21	CAP	CAP	NNP
cord-291400-o9skj94r	32	22	,	,	,
cord-291400-o9skj94r	32	23	and	and	CC
cord-291400-o9skj94r	32	24	no	no	DT
cord-291400-o9skj94r	32	25	specific	specific	JJ
cord-291400-o9skj94r	32	26	cause	cause	NN
cord-291400-o9skj94r	32	27	was	be	VBD
cord-291400-o9skj94r	32	28	found	find	VBN
cord-291400-o9skj94r	32	29	in	in	IN
cord-291400-o9skj94r	32	30	25	25	CD
cord-291400-o9skj94r	32	31	%	%	NN
cord-291400-o9skj94r	32	32	to	to	TO
cord-291400-o9skj94r	32	33	50	50	CD
cord-291400-o9skj94r	32	34	%	%	NN
cord-291400-o9skj94r	32	35	of	of	IN
cord-291400-o9skj94r	32	36	patients	patient	NNS
cord-291400-o9skj94r	32	37	[	[	-LRB-
cord-291400-o9skj94r	32	38	12	12	CD
cord-291400-o9skj94r	32	39	,	,	,
cord-291400-o9skj94r	32	40	15	15	CD
cord-291400-o9skj94r	32	41	]	]	-RRB-
cord-291400-o9skj94r	32	42	.	.	.
cord-291400-o9skj94r	33	1	Approximately	approximately	RB
cord-291400-o9skj94r	33	2	one	one	CD
cord-291400-o9skj94r	33	3	third	third	NN
cord-291400-o9skj94r	33	4	of	of	IN
cord-291400-o9skj94r	33	5	patients	patient	NNS
cord-291400-o9skj94r	33	6	had	have	VBD
cord-291400-o9skj94r	33	7	taken	take	VBN
cord-291400-o9skj94r	33	8	at	at	RB
cord-291400-o9skj94r	33	9	least	least	RBS
cord-291400-o9skj94r	33	10	one	one	CD
cord-291400-o9skj94r	33	11	dose	dose	NN
cord-291400-o9skj94r	33	12	of	of	IN
cord-291400-o9skj94r	33	13	antibiotics	antibiotic	NNS
cord-291400-o9skj94r	33	14	before	before	IN
cord-291400-o9skj94r	33	15	presenting	present	VBG
cord-291400-o9skj94r	33	16	to	to	IN
cord-291400-o9skj94r	33	17	the	the	DT
cord-291400-o9skj94r	33	18	physician	physician	NN
cord-291400-o9skj94r	33	19	.	.	.
cord-291400-o9skj94r	34	1	The	the	DT
cord-291400-o9skj94r	34	2	services	service	NNS
cord-291400-o9skj94r	34	3	of	of	IN
cord-291400-o9skj94r	34	4	many	many	JJ
cord-291400-o9skj94r	34	5	microbiology	microbiology	NN
cord-291400-o9skj94r	34	6	laboratories	laboratory	NNS
cord-291400-o9skj94r	34	7	have	have	VBP
cord-291400-o9skj94r	34	8	been	be	VBN
cord-291400-o9skj94r	34	9	scaled	scale	VBN
cord-291400-o9skj94r	34	10	back	back	RB
cord-291400-o9skj94r	34	11	because	because	IN
cord-291400-o9skj94r	34	12	of	of	IN
cord-291400-o9skj94r	34	13	hospital	hospital	NN
cord-291400-o9skj94r	34	14	budgetary	budgetary	JJ
cord-291400-o9skj94r	34	15	constraints	constraint	NNS
cord-291400-o9skj94r	34	16	.	.	.
cord-291400-o9skj94r	35	1	The	the	DT
cord-291400-o9skj94r	35	2	consolidation	consolidation	NN
cord-291400-o9skj94r	35	3	of	of	IN
cord-291400-o9skj94r	35	4	many	many	JJ
cord-291400-o9skj94r	35	5	hospitals	hospital	NNS
cord-291400-o9skj94r	35	6	has	have	VBZ
cord-291400-o9skj94r	35	7	led	lead	VBN
cord-291400-o9skj94r	35	8	to	to	IN
cord-291400-o9skj94r	35	9	the	the	DT
cord-291400-o9skj94r	35	10	use	use	NN
cord-291400-o9skj94r	35	11	of	of	IN
cord-291400-o9skj94r	35	12	centralized	centralized	JJ
cord-291400-o9skj94r	35	13	or	or	CC
cord-291400-o9skj94r	35	14	reference	reference	NN
cord-291400-o9skj94r	35	15	laboratories	laboratory	NNS
cord-291400-o9skj94r	35	16	,	,	,
cord-291400-o9skj94r	35	17	which	which	WDT
cord-291400-o9skj94r	35	18	prolongs	prolong	VBZ
cord-291400-o9skj94r	35	19	the	the	DT
cord-291400-o9skj94r	35	20	time	time	NN
cord-291400-o9skj94r	35	21	from	from	IN
cord-291400-o9skj94r	35	22	specimen	specimen	JJ
cord-291400-o9skj94r	35	23	collection	collection	NN
cord-291400-o9skj94r	35	24	to	to	IN
cord-291400-o9skj94r	35	25	processing	processing	NN
cord-291400-o9skj94r	35	26	.	.	.
cord-291400-o9skj94r	36	1	These	these	DT
cord-291400-o9skj94r	36	2	factors	factor	NNS
cord-291400-o9skj94r	36	3	have	have	VBP
cord-291400-o9skj94r	36	4	decreased	decrease	VBN
cord-291400-o9skj94r	36	5	the	the	DT
cord-291400-o9skj94r	36	6	ability	ability	NN
cord-291400-o9skj94r	36	7	to	to	TO
cord-291400-o9skj94r	36	8	culture	culture	VB
cord-291400-o9skj94r	36	9	pyogenic	pyogenic	JJ
cord-291400-o9skj94r	36	10	organisms	organism	NNS
cord-291400-o9skj94r	36	11	,	,	,
cord-291400-o9skj94r	36	12	such	such	JJ
cord-291400-o9skj94r	36	13	as	as	IN
cord-291400-o9skj94r	36	14	S	s	NN
cord-291400-o9skj94r	36	15	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	36	16	.	.	.
cord-291400-o9skj94r	37	1	Centers	center	NNS
cord-291400-o9skj94r	37	2	that	that	WDT
cord-291400-o9skj94r	37	3	use	use	VBP
cord-291400-o9skj94r	37	4	methods	method	NNS
cord-291400-o9skj94r	37	5	in	in	IN
cord-291400-o9skj94r	37	6	addition	addition	NN
cord-291400-o9skj94r	37	7	to	to	IN
cord-291400-o9skj94r	37	8	culture	culture	NN
cord-291400-o9skj94r	37	9	for	for	IN
cord-291400-o9skj94r	37	10	S	s	NN
cord-291400-o9skj94r	37	11	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	37	12	(	(	-LRB-
cord-291400-o9skj94r	37	13	antigen	antigen	NN
cord-291400-o9skj94r	37	14	detection	detection	NN
cord-291400-o9skj94r	37	15	,	,	,
cord-291400-o9skj94r	37	16	serological	serological	JJ
cord-291400-o9skj94r	37	17	means	mean	NNS
cord-291400-o9skj94r	37	18	)	)	-RRB-
cord-291400-o9skj94r	37	19	have	have	VBP
cord-291400-o9skj94r	37	20	reported	report	VBN
cord-291400-o9skj94r	37	21	finding	find	VBG
cord-291400-o9skj94r	37	22	more	more	JJR
cord-291400-o9skj94r	37	23	cases	case	NNS
cord-291400-o9skj94r	37	24	of	of	IN
cord-291400-o9skj94r	37	25	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	37	26	pneumonia	pneumonia	NN
cord-291400-o9skj94r	37	27	than	than	IN
cord-291400-o9skj94r	37	28	cases	case	NNS
cord-291400-o9skj94r	37	29	of	of	IN
cord-291400-o9skj94r	37	30	pneumonia	pneumonia	NN
cord-291400-o9skj94r	37	31	caused	cause	VBN
cord-291400-o9skj94r	37	32	by	by	IN
cord-291400-o9skj94r	37	33	unidentified	unidentified	JJ
cord-291400-o9skj94r	37	34	pathogens	pathogen	NNS
cord-291400-o9skj94r	37	35	,	,	,
cord-291400-o9skj94r	37	36	suggesting	suggest	VBG
cord-291400-o9skj94r	37	37	that	that	IN
cord-291400-o9skj94r	37	38	many	many	JJ
cord-291400-o9skj94r	37	39	patients	patient	NNS
cord-291400-o9skj94r	37	40	without	without	IN
cord-291400-o9skj94r	37	41	a	a	DT
cord-291400-o9skj94r	37	42	definable	definable	JJ
cord-291400-o9skj94r	37	43	cause	cause	NN
cord-291400-o9skj94r	37	44	have	have	VBP
cord-291400-o9skj94r	37	45	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	37	46	pneumonia	pneumonia	NN
cord-291400-o9skj94r	37	47	[	[	-LRB-
cord-291400-o9skj94r	37	48	10	10	CD
cord-291400-o9skj94r	37	49	,	,	,
cord-291400-o9skj94r	37	50	16	16	CD
cord-291400-o9skj94r	37	51	]	]	-RRB-
cord-291400-o9skj94r	37	52	.	.	.
cord-291400-o9skj94r	38	1	Patients	patient	NNS
cord-291400-o9skj94r	38	2	with	with	IN
cord-291400-o9skj94r	38	3	increased	increase	VBN
cord-291400-o9skj94r	38	4	susceptibility	susceptibility	NN
cord-291400-o9skj94r	38	5	to	to	IN
cord-291400-o9skj94r	38	6	pneumococcus	pneumococcus	NNP
cord-291400-o9skj94r	38	7	may	may	MD
cord-291400-o9skj94r	38	8	be	be	VB
cord-291400-o9skj94r	38	9	susceptible	susceptible	JJ
cord-291400-o9skj94r	38	10	to	to	IN
cord-291400-o9skj94r	38	11	other	other	JJ
cord-291400-o9skj94r	38	12	pulmonary	pulmonary	JJ
cord-291400-o9skj94r	38	13	pathogens	pathogen	NNS
cord-291400-o9skj94r	38	14	,	,	,
cord-291400-o9skj94r	38	15	leading	lead	VBG
cord-291400-o9skj94r	38	16	to	to	IN
cord-291400-o9skj94r	38	17	dual	dual	JJ
cord-291400-o9skj94r	38	18	infections	infection	NNS
cord-291400-o9skj94r	38	19	.	.	.
cord-291400-o9skj94r	39	1	Some	some	DT
cord-291400-o9skj94r	39	2	pathogens	pathogen	NNS
cord-291400-o9skj94r	39	3	,	,	,
cord-291400-o9skj94r	39	4	such	such	JJ
cord-291400-o9skj94r	39	5	as	as	IN
cord-291400-o9skj94r	39	6	influenza	influenza	NN
cord-291400-o9skj94r	39	7	virus	virus	NN
cord-291400-o9skj94r	39	8	,	,	,
cord-291400-o9skj94r	39	9	render	render	VB
cord-291400-o9skj94r	39	10	the	the	DT
cord-291400-o9skj94r	39	11	host	host	NN
cord-291400-o9skj94r	39	12	more	more	RBR
cord-291400-o9skj94r	39	13	susceptible	susceptible	JJ
cord-291400-o9skj94r	39	14	to	to	IN
cord-291400-o9skj94r	39	15	the	the	DT
cord-291400-o9skj94r	39	16	pneumococcus	pneumococcus	NN
cord-291400-o9skj94r	39	17	[	[	-LRB-
cord-291400-o9skj94r	39	18	24	24	CD
cord-291400-o9skj94r	39	19	]	]	-RRB-
cord-291400-o9skj94r	39	20	.	.	.
cord-291400-o9skj94r	40	1	Predisposition	predisposition	NN
cord-291400-o9skj94r	40	2	to	to	IN
cord-291400-o9skj94r	40	3	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	40	4	infection	infection	NN
cord-291400-o9skj94r	40	5	may	may	MD
cord-291400-o9skj94r	40	6	hold	hold	VB
cord-291400-o9skj94r	40	7	true	true	JJ
cord-291400-o9skj94r	40	8	for	for	IN
cord-291400-o9skj94r	40	9	patients	patient	NNS
cord-291400-o9skj94r	40	10	with	with	IN
cord-291400-o9skj94r	40	11	antecedent	antecedent	JJ
cord-291400-o9skj94r	40	12	M	M	NNP
cord-291400-o9skj94r	40	13	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	40	14	and	and	CC
cord-291400-o9skj94r	40	15	C	c	NN
cord-291400-o9skj94r	40	16	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	40	17	infections	infection	NNS
cord-291400-o9skj94r	40	18	[	[	-LRB-
cord-291400-o9skj94r	40	19	13	13	CD
cord-291400-o9skj94r	40	20	]	]	-RRB-
cord-291400-o9skj94r	41	1	[	[	-LRB-
cord-291400-o9skj94r	41	2	14	14	CD
cord-291400-o9skj94r	41	3	]	]	-RRB-
cord-291400-o9skj94r	41	4	[	[	-LRB-
cord-291400-o9skj94r	41	5	15	15	CD
cord-291400-o9skj94r	41	6	]	]	-RRB-
cord-291400-o9skj94r	41	7	[	[	-LRB-
cord-291400-o9skj94r	41	8	16	16	CD
cord-291400-o9skj94r	41	9	]	]	-RRB-
cord-291400-o9skj94r	41	10	.	.	.
cord-291400-o9skj94r	42	1	Lessons	lesson	NNS
cord-291400-o9skj94r	42	2	learned	learn	VBD
cord-291400-o9skj94r	42	3	from	from	IN
cord-291400-o9skj94r	42	4	the	the	DT
cord-291400-o9skj94r	42	5	series	series	NN
cord-291400-o9skj94r	42	6	of	of	IN
cord-291400-o9skj94r	42	7	patients	patient	NNS
cord-291400-o9skj94r	42	8	with	with	IN
cord-291400-o9skj94r	42	9	CAP	CAP	NNP
cord-291400-o9skj94r	42	10	include	include	VBP
cord-291400-o9skj94r	42	11	the	the	DT
cord-291400-o9skj94r	42	12	fact	fact	NN
cord-291400-o9skj94r	42	13	that	that	IN
cord-291400-o9skj94r	42	14	it	-PRON-	PRP
cord-291400-o9skj94r	42	15	may	may	MD
cord-291400-o9skj94r	42	16	be	be	VB
cord-291400-o9skj94r	42	17	difficult	difficult	JJ
cord-291400-o9skj94r	42	18	to	to	TO
cord-291400-o9skj94r	42	19	identify	identify	VB
cord-291400-o9skj94r	42	20	cases	case	NNS
cord-291400-o9skj94r	42	21	of	of	IN
cord-291400-o9skj94r	42	22	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	42	23	pneumonia	pneumonia	NN
cord-291400-o9skj94r	42	24	,	,	,
cord-291400-o9skj94r	42	25	patients	patient	NNS
cord-291400-o9skj94r	42	26	with	with	IN
cord-291400-o9skj94r	42	27	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	42	28	pneumonia	pneumonia	NN
cord-291400-o9skj94r	42	29	may	may	MD
cord-291400-o9skj94r	42	30	have	have	VB
cord-291400-o9skj94r	42	31	additional	additional	JJ
cord-291400-o9skj94r	42	32	infections	infection	NNS
cord-291400-o9skj94r	42	33	[	[	-LRB-
cord-291400-o9skj94r	42	34	25	25	CD
cord-291400-o9skj94r	42	35	,	,	,
cord-291400-o9skj94r	42	36	26	26	CD
cord-291400-o9skj94r	42	37	]	]	-RRB-
cord-291400-o9skj94r	42	38	,	,	,
cord-291400-o9skj94r	42	39	and	and	CC
cord-291400-o9skj94r	42	40	patients	patient	NNS
cord-291400-o9skj94r	42	41	with	with	IN
cord-291400-o9skj94r	42	42	pneumonia	pneumonia	NN
cord-291400-o9skj94r	42	43	reflect	reflect	VBP
cord-291400-o9skj94r	42	44	the	the	DT
cord-291400-o9skj94r	42	45	demographics	demographic	NNS
cord-291400-o9skj94r	42	46	of	of	IN
cord-291400-o9skj94r	42	47	the	the	DT
cord-291400-o9skj94r	42	48	changing	change	VBG
cord-291400-o9skj94r	42	49	U.S.	U.S.	NNP
cord-291400-o9skj94r	42	50	population	population	NN
cord-291400-o9skj94r	42	51	.	.	.
cord-291400-o9skj94r	43	1	Studies	study	NNS
cord-291400-o9skj94r	43	2	of	of	IN
cord-291400-o9skj94r	43	3	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	43	4	bacteremia	bacteremia	NN
cord-291400-o9skj94r	43	5	suggest	suggest	VBP
cord-291400-o9skj94r	43	6	that	that	IN
cord-291400-o9skj94r	43	7	the	the	DT
cord-291400-o9skj94r	43	8	incidence	incidence	NN
cord-291400-o9skj94r	43	9	of	of	IN
cord-291400-o9skj94r	43	10	disease	disease	NN
cord-291400-o9skj94r	43	11	is	be	VBZ
cord-291400-o9skj94r	43	12	increasing	increase	VBG
cord-291400-o9skj94r	43	13	in	in	IN
cord-291400-o9skj94r	43	14	the	the	DT
cord-291400-o9skj94r	43	15	U.S.	U.S.	NNP
cord-291400-o9skj94r	43	16	population	population	NN
cord-291400-o9skj94r	43	17	[	[	-LRB-
cord-291400-o9skj94r	43	18	5	5	CD
cord-291400-o9skj94r	43	19	,	,	,
cord-291400-o9skj94r	43	20	[	[	-LRB-
cord-291400-o9skj94r	43	21	27	27	CD
cord-291400-o9skj94r	43	22	]	]	-RRB-
cord-291400-o9skj94r	43	23	[	[	-LRB-
cord-291400-o9skj94r	43	24	28	28	CD
cord-291400-o9skj94r	43	25	]	]	-RRB-
cord-291400-o9skj94r	43	26	[	[	-LRB-
cord-291400-o9skj94r	43	27	29	29	CD
cord-291400-o9skj94r	43	28	]	]	-RRB-
cord-291400-o9skj94r	43	29	.	.	.
cord-291400-o9skj94r	44	1	Pathophysiology	pathophysiology	NN
cord-291400-o9skj94r	44	2	S	S	NNP
cord-291400-o9skj94r	44	3	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	44	4	is	be	VBZ
cord-291400-o9skj94r	44	5	acquired	acquire	VBN
cord-291400-o9skj94r	44	6	through	through	IN
cord-291400-o9skj94r	44	7	inhalation	inhalation	NN
cord-291400-o9skj94r	44	8	of	of	IN
cord-291400-o9skj94r	44	9	large	large	JJ
cord-291400-o9skj94r	44	10	droplets	droplet	NNS
cord-291400-o9skj94r	44	11	from	from	IN
cord-291400-o9skj94r	44	12	a	a	DT
cord-291400-o9skj94r	44	13	carrier	carrier	NN
cord-291400-o9skj94r	44	14	.	.	.
cord-291400-o9skj94r	45	1	The	the	DT
cord-291400-o9skj94r	45	2	pneumococcus	pneumococcus	NN
cord-291400-o9skj94r	45	3	must	must	MD
cord-291400-o9skj94r	45	4	colonize	colonize	VB
cord-291400-o9skj94r	45	5	the	the	DT
cord-291400-o9skj94r	45	6	oropharyngeal	oropharyngeal	JJ
cord-291400-o9skj94r	45	7	epithelial	epithelial	JJ
cord-291400-o9skj94r	45	8	cells	cell	NNS
cord-291400-o9skj94r	45	9	and	and	CC
cord-291400-o9skj94r	45	10	then	then	RB
cord-291400-o9skj94r	45	11	be	be	VB
cord-291400-o9skj94r	45	12	able	able	JJ
cord-291400-o9skj94r	45	13	to	to	TO
cord-291400-o9skj94r	45	14	multiply	multiply	VB
cord-291400-o9skj94r	45	15	.	.	.
cord-291400-o9skj94r	46	1	Microaspiration	Microaspiration	NNP
cord-291400-o9skj94r	46	2	of	of	IN
cord-291400-o9skj94r	46	3	these	these	DT
cord-291400-o9skj94r	46	4	organisms	organism	NNS
cord-291400-o9skj94r	46	5	to	to	IN
cord-291400-o9skj94r	46	6	the	the	DT
cord-291400-o9skj94r	46	7	lungs	lung	NNS
cord-291400-o9skj94r	46	8	causes	cause	VBZ
cord-291400-o9skj94r	46	9	the	the	DT
cord-291400-o9skj94r	46	10	pneumonia	pneumonia	NN
cord-291400-o9skj94r	46	11	.	.	.
cord-291400-o9skj94r	47	1	The	the	DT
cord-291400-o9skj94r	47	2	efficiency	efficiency	NN
cord-291400-o9skj94r	47	3	of	of	IN
cord-291400-o9skj94r	47	4	this	this	DT
cord-291400-o9skj94r	47	5	process	process	NN
cord-291400-o9skj94r	47	6	is	be	VBZ
cord-291400-o9skj94r	47	7	low	low	JJ
cord-291400-o9skj94r	47	8	in	in	IN
cord-291400-o9skj94r	47	9	most	most	JJS
cord-291400-o9skj94r	47	10	instances	instance	NNS
cord-291400-o9skj94r	47	11	,	,	,
cord-291400-o9skj94r	47	12	as	as	IN
cord-291400-o9skj94r	47	13	patients	patient	NNS
cord-291400-o9skj94r	47	14	with	with	IN
cord-291400-o9skj94r	47	15	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	47	16	pneumonia	pneumonia	NN
cord-291400-o9skj94r	47	17	are	be	VBP
cord-291400-o9skj94r	47	18	not	not	RB
cord-291400-o9skj94r	47	19	placed	place	VBN
cord-291400-o9skj94r	47	20	in	in	IN
cord-291400-o9skj94r	47	21	respiratory	respiratory	JJ
cord-291400-o9skj94r	47	22	isolation	isolation	NN
cord-291400-o9skj94r	47	23	.	.	.
cord-291400-o9skj94r	48	1	In	in	IN
cord-291400-o9skj94r	48	2	certain	certain	JJ
cord-291400-o9skj94r	48	3	closed	closed	JJ
cord-291400-o9skj94r	48	4	populations	population	NNS
cord-291400-o9skj94r	48	5	,	,	,
cord-291400-o9skj94r	48	6	such	such	JJ
cord-291400-o9skj94r	48	7	as	as	IN
cord-291400-o9skj94r	48	8	jails	jail	NNS
cord-291400-o9skj94r	48	9	,	,	,
cord-291400-o9skj94r	48	10	long	long	JJ
cord-291400-o9skj94r	48	11	-	-	HYPH
cord-291400-o9skj94r	48	12	term	term	NN
cord-291400-o9skj94r	48	13	care	care	NN
cord-291400-o9skj94r	48	14	facilities	facility	NNS
cord-291400-o9skj94r	48	15	,	,	,
cord-291400-o9skj94r	48	16	and	and	CC
cord-291400-o9skj94r	48	17	day	day	NN
cord-291400-o9skj94r	48	18	care	care	NN
cord-291400-o9skj94r	48	19	centers	center	NNS
cord-291400-o9skj94r	48	20	,	,	,
cord-291400-o9skj94r	48	21	the	the	DT
cord-291400-o9skj94r	48	22	process	process	NN
cord-291400-o9skj94r	48	23	'	'	''
cord-291400-o9skj94r	48	24	efficiency	efficiency	NN
cord-291400-o9skj94r	48	25	is	be	VBZ
cord-291400-o9skj94r	48	26	higher	high	JJR
cord-291400-o9skj94r	48	27	,	,	,
cord-291400-o9skj94r	48	28	and	and	CC
cord-291400-o9skj94r	48	29	outbreaks	outbreak	NNS
cord-291400-o9skj94r	48	30	can	can	MD
cord-291400-o9skj94r	48	31	occur	occur	VB
cord-291400-o9skj94r	48	32	.	.	.
cord-291400-o9skj94r	49	1	The	the	DT
cord-291400-o9skj94r	49	2	defense	defense	NN
cord-291400-o9skj94r	49	3	system	system	NN
cord-291400-o9skj94r	49	4	of	of	IN
cord-291400-o9skj94r	49	5	the	the	DT
cord-291400-o9skj94r	49	6	host	host	NN
cord-291400-o9skj94r	49	7	is	be	VBZ
cord-291400-o9skj94r	49	8	helpful	helpful	JJ
cord-291400-o9skj94r	49	9	in	in	IN
cord-291400-o9skj94r	49	10	controlling	control	VBG
cord-291400-o9skj94r	49	11	S	s	NN
cord-291400-o9skj94r	49	12	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	49	13	attachment	attachment	NN
cord-291400-o9skj94r	49	14	(	(	-LRB-
cord-291400-o9skj94r	49	15	conjugate	conjugate	JJ
cord-291400-o9skj94r	49	16	vaccine	vaccine	NN
cord-291400-o9skj94r	49	17	)	)	-RRB-
cord-291400-o9skj94r	49	18	,	,	,
cord-291400-o9skj94r	49	19	growth	growth	NN
cord-291400-o9skj94r	49	20	,	,	,
cord-291400-o9skj94r	49	21	and	and	CC
cord-291400-o9skj94r	49	22	spread	spread	VBD
cord-291400-o9skj94r	49	23	to	to	IN
cord-291400-o9skj94r	49	24	lungs	lung	NNS
cord-291400-o9skj94r	49	25	.	.	.
cord-291400-o9skj94r	50	1	Factors	factor	NNS
cord-291400-o9skj94r	50	2	that	that	WDT
cord-291400-o9skj94r	50	3	inhibit	inhibit	VBP
cord-291400-o9skj94r	50	4	ciliary	ciliary	NN
cord-291400-o9skj94r	50	5	function	function	NN
cord-291400-o9skj94r	50	6	,	,	,
cord-291400-o9skj94r	50	7	such	such	JJ
cord-291400-o9skj94r	50	8	as	as	IN
cord-291400-o9skj94r	50	9	smoking	smoking	NN
cord-291400-o9skj94r	50	10	or	or	CC
cord-291400-o9skj94r	50	11	viral	viral	JJ
cord-291400-o9skj94r	50	12	infections	infection	NNS
cord-291400-o9skj94r	50	13	,	,	,
cord-291400-o9skj94r	50	14	increase	increase	VB
cord-291400-o9skj94r	50	15	the	the	DT
cord-291400-o9skj94r	50	16	likelihood	likelihood	NN
cord-291400-o9skj94r	50	17	of	of	IN
cord-291400-o9skj94r	50	18	acquiring	acquire	VBG
cord-291400-o9skj94r	50	19	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	50	20	pneumonia	pneumonia	NN
cord-291400-o9skj94r	50	21	.	.	.
cord-291400-o9skj94r	51	1	Once	once	RB
cord-291400-o9skj94r	51	2	in	in	IN
cord-291400-o9skj94r	51	3	the	the	DT
cord-291400-o9skj94r	51	4	pulmonary	pulmonary	JJ
cord-291400-o9skj94r	51	5	parenchyma	parenchyma	NN
cord-291400-o9skj94r	51	6	,	,	,
cord-291400-o9skj94r	51	7	the	the	DT
cord-291400-o9skj94r	51	8	pneumococcus	pneumococcus	NN
cord-291400-o9skj94r	51	9	elicits	elicit	VBZ
cord-291400-o9skj94r	51	10	an	an	DT
cord-291400-o9skj94r	51	11	intense	intense	JJ
cord-291400-o9skj94r	51	12	inflammatory	inflammatory	JJ
cord-291400-o9skj94r	51	13	reaction	reaction	NN
cord-291400-o9skj94r	51	14	.	.	.
cord-291400-o9skj94r	52	1	Phagocytosis	Phagocytosis	NNP
cord-291400-o9skj94r	52	2	in	in	IN
cord-291400-o9skj94r	52	3	enhanced	enhance	VBN
cord-291400-o9skj94r	52	4	if	if	IN
cord-291400-o9skj94r	52	5	type	type	NN
cord-291400-o9skj94r	52	6	-	-	HYPH
cord-291400-o9skj94r	52	7	specific	specific	JJ
cord-291400-o9skj94r	52	8	opsonizing	opsonize	VBG
cord-291400-o9skj94r	52	9	antibodies	antibody	NNS
cord-291400-o9skj94r	52	10	are	be	VBP
cord-291400-o9skj94r	52	11	present	present	JJ
cord-291400-o9skj94r	52	12	.	.	.
cord-291400-o9skj94r	53	1	Bacteremia	Bacteremia	NNP
cord-291400-o9skj94r	53	2	is	be	VBZ
cord-291400-o9skj94r	53	3	more	more	RBR
cord-291400-o9skj94r	53	4	likely	likely	JJ
cord-291400-o9skj94r	53	5	to	to	TO
cord-291400-o9skj94r	53	6	occur	occur	VB
cord-291400-o9skj94r	53	7	in	in	IN
cord-291400-o9skj94r	53	8	the	the	DT
cord-291400-o9skj94r	53	9	absence	absence	NN
cord-291400-o9skj94r	53	10	of	of	IN
cord-291400-o9skj94r	53	11	these	these	DT
cord-291400-o9skj94r	53	12	antibodies	antibody	NNS
cord-291400-o9skj94r	53	13	(	(	-LRB-
cord-291400-o9skj94r	53	14	hypogammaglobulinemia	hypogammaglobulinemia	NNP
cord-291400-o9skj94r	53	15	)	)	-RRB-
cord-291400-o9skj94r	53	16	,	,	,
cord-291400-o9skj94r	53	17	diminished	diminished	JJ
cord-291400-o9skj94r	53	18	function	function	NN
cord-291400-o9skj94r	53	19	of	of	IN
cord-291400-o9skj94r	53	20	phagocytic	phagocytic	JJ
cord-291400-o9skj94r	53	21	cells	cell	NNS
cord-291400-o9skj94r	53	22	(	(	-LRB-
cord-291400-o9skj94r	53	23	alcoholism	alcoholism	NN
cord-291400-o9skj94r	53	24	)	)	-RRB-
cord-291400-o9skj94r	53	25	,	,	,
cord-291400-o9skj94r	53	26	decreased	decrease	VBD
cord-291400-o9skj94r	53	27	inflammatory	inflammatory	JJ
cord-291400-o9skj94r	53	28	response	response	NN
cord-291400-o9skj94r	53	29	(	(	-LRB-
cord-291400-o9skj94r	53	30	complement	complement	NN
cord-291400-o9skj94r	53	31	deficiencies	deficiency	NNS
cord-291400-o9skj94r	53	32	)	)	-RRB-
cord-291400-o9skj94r	53	33	,	,	,
cord-291400-o9skj94r	53	34	and	and	CC
cord-291400-o9skj94r	53	35	the	the	DT
cord-291400-o9skj94r	53	36	absence	absence	NN
cord-291400-o9skj94r	53	37	of	of	IN
cord-291400-o9skj94r	53	38	the	the	DT
cord-291400-o9skj94r	53	39	clearing	clearing	NN
cord-291400-o9skj94r	53	40	function	function	NN
cord-291400-o9skj94r	53	41	of	of	IN
cord-291400-o9skj94r	53	42	the	the	DT
cord-291400-o9skj94r	53	43	spleen	spleen	NNS
cord-291400-o9skj94r	53	44	(	(	-LRB-
cord-291400-o9skj94r	53	45	sickle	sickle	NN
cord-291400-o9skj94r	53	46	cell	cell	NN
cord-291400-o9skj94r	53	47	disease	disease	NN
cord-291400-o9skj94r	53	48	,	,	,
cord-291400-o9skj94r	53	49	splenectomy	splenectomy	NN
cord-291400-o9skj94r	53	50	)	)	-RRB-
cord-291400-o9skj94r	53	51	.	.	.
cord-291400-o9skj94r	54	1	Before	before	IN
cord-291400-o9skj94r	54	2	the	the	DT
cord-291400-o9skj94r	54	3	early	early	JJ
cord-291400-o9skj94r	54	4	1990s	1990	NNS
cord-291400-o9skj94r	54	5	,	,	,
cord-291400-o9skj94r	54	6	most	most	JJS
cord-291400-o9skj94r	54	7	S	s	NN
cord-291400-o9skj94r	54	8	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	54	9	isolates	isolate	NNS
cord-291400-o9skj94r	54	10	were	be	VBD
cord-291400-o9skj94r	54	11	susceptible	susceptible	JJ
cord-291400-o9skj94r	54	12	to	to	IN
cord-291400-o9skj94r	54	13	most	most	JJS
cord-291400-o9skj94r	54	14	of	of	IN
cord-291400-o9skj94r	54	15	the	the	DT
cord-291400-o9skj94r	54	16	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	54	17	agents	agent	NNS
cord-291400-o9skj94r	54	18	that	that	WDT
cord-291400-o9skj94r	54	19	were	be	VBD
cord-291400-o9skj94r	54	20	used	use	VBN
cord-291400-o9skj94r	54	21	to	to	TO
cord-291400-o9skj94r	54	22	treat	treat	VB
cord-291400-o9skj94r	54	23	respiratory	respiratory	JJ
cord-291400-o9skj94r	54	24	infections	infection	NNS
cord-291400-o9skj94r	54	25	.	.	.
cord-291400-o9skj94r	55	1	Since	since	IN
cord-291400-o9skj94r	55	2	then	then	RB
cord-291400-o9skj94r	55	3	,	,	,
cord-291400-o9skj94r	55	4	higher	high	JJR
cord-291400-o9skj94r	55	5	concentrations	concentration	NNS
cord-291400-o9skj94r	55	6	of	of	IN
cord-291400-o9skj94r	55	7	penicillin	penicillin	NN
cord-291400-o9skj94r	55	8	have	have	VBP
cord-291400-o9skj94r	55	9	been	be	VBN
cord-291400-o9skj94r	55	10	required	require	VBN
cord-291400-o9skj94r	55	11	to	to	TO
cord-291400-o9skj94r	55	12	inhibit	inhibit	VB
cord-291400-o9skj94r	55	13	growth	growth	NN
cord-291400-o9skj94r	55	14	of	of	IN
cord-291400-o9skj94r	55	15	the	the	DT
cord-291400-o9skj94r	55	16	pneumococcus	pneumococcus	NN
cord-291400-o9skj94r	55	17	[	[	-LRB-
cord-291400-o9skj94r	55	18	4	4	CD
cord-291400-o9skj94r	55	19	]	]	-RRB-
cord-291400-o9skj94r	55	20	.	.	.
cord-291400-o9skj94r	56	1	The	the	DT
cord-291400-o9skj94r	56	2	changing	change	VBG
cord-291400-o9skj94r	56	3	susceptibilities	susceptibility	NNS
cord-291400-o9skj94r	56	4	of	of	IN
cord-291400-o9skj94r	56	5	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	56	6	agents	agent	NNS
cord-291400-o9skj94r	56	7	are	be	VBP
cord-291400-o9skj94r	56	8	discussed	discuss	VBN
cord-291400-o9skj94r	56	9	in	in	IN
cord-291400-o9skj94r	56	10	detail	detail	NN
cord-291400-o9skj94r	56	11	in	in	IN
cord-291400-o9skj94r	56	12	another	another	DT
cord-291400-o9skj94r	56	13	article	article	NN
cord-291400-o9skj94r	56	14	in	in	IN
cord-291400-o9skj94r	56	15	this	this	DT
cord-291400-o9skj94r	56	16	issue	issue	NN
cord-291400-o9skj94r	56	17	.	.	.
cord-291400-o9skj94r	57	1	In	in	IN
cord-291400-o9skj94r	57	2	general	general	JJ
cord-291400-o9skj94r	57	3	,	,	,
cord-291400-o9skj94r	57	4	b	b	NN
cord-291400-o9skj94r	57	5	-	-	HYPH
cord-291400-o9skj94r	57	6	lactam	lactam	NN
cord-291400-o9skj94r	57	7	antibiotics	antibiotic	NNS
cord-291400-o9skj94r	57	8	effectively	effectively	RB
cord-291400-o9skj94r	57	9	treat	treat	VBP
cord-291400-o9skj94r	57	10	nonmeningeal	nonmeningeal	NNP
cord-291400-o9skj94r	57	11	(	(	-LRB-
cord-291400-o9skj94r	57	12	ie	ie	FW
cord-291400-o9skj94r	57	13	,	,	,
cord-291400-o9skj94r	57	14	pneumonia	pneumonia	NN
cord-291400-o9skj94r	57	15	,	,	,
cord-291400-o9skj94r	57	16	bacteremia	bacteremia	NN
cord-291400-o9skj94r	57	17	)	)	-RRB-
cord-291400-o9skj94r	57	18	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	57	19	disease	disease	NN
cord-291400-o9skj94r	57	20	in	in	IN
cord-291400-o9skj94r	57	21	most	most	JJS
cord-291400-o9skj94r	57	22	cases	case	NNS
cord-291400-o9skj94r	57	23	.	.	.
cord-291400-o9skj94r	58	1	Although	although	IN
cord-291400-o9skj94r	58	2	several	several	JJ
cord-291400-o9skj94r	58	3	respiratory	respiratory	JJ
cord-291400-o9skj94r	58	4	pathogens	pathogen	NNS
cord-291400-o9skj94r	58	5	may	may	MD
cord-291400-o9skj94r	58	6	have	have	VB
cord-291400-o9skj94r	58	7	a	a	DT
cord-291400-o9skj94r	58	8	higher	high	JJR
cord-291400-o9skj94r	58	9	CFR	CFR	NNP
cord-291400-o9skj94r	58	10	(	(	-LRB-
cord-291400-o9skj94r	58	11	rate	rate	NN
cord-291400-o9skj94r	58	12	for	for	IN
cord-291400-o9skj94r	58	13	Pseudomonas	Pseudomonas	NNP
cord-291400-o9skj94r	58	14	aeruginosa	aeruginosa	NN
cord-291400-o9skj94r	58	15	,	,	,
cord-291400-o9skj94r	58	16	70	70	CD
cord-291400-o9skj94r	58	17	%	%	NN
cord-291400-o9skj94r	58	18	)	)	-RRB-
cord-291400-o9skj94r	58	19	than	than	IN
cord-291400-o9skj94r	58	20	S	S	NNP
cord-291400-o9skj94r	58	21	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	58	22	(	(	-LRB-
cord-291400-o9skj94r	58	23	10%-20	10%-20	CD
cord-291400-o9skj94r	58	24	%	%	NN
cord-291400-o9skj94r	58	25	)	)	-RRB-
cord-291400-o9skj94r	58	26	,	,	,
cord-291400-o9skj94r	58	27	the	the	DT
cord-291400-o9skj94r	58	28	total	total	JJ
cord-291400-o9skj94r	58	29	number	number	NN
cord-291400-o9skj94r	58	30	of	of	IN
cord-291400-o9skj94r	58	31	CAP	cap	NN
cord-291400-o9skj94r	58	32	-	-	HYPH
cord-291400-o9skj94r	58	33	related	relate	VBN
cord-291400-o9skj94r	58	34	deaths	death	NNS
cord-291400-o9skj94r	58	35	caused	cause	VBN
cord-291400-o9skj94r	58	36	by	by	IN
cord-291400-o9skj94r	58	37	pneumococci	pneumococci	NNP
cord-291400-o9skj94r	58	38	exceeds	exceed	VBZ
cord-291400-o9skj94r	58	39	the	the	DT
cord-291400-o9skj94r	58	40	number	number	NN
cord-291400-o9skj94r	58	41	of	of	IN
cord-291400-o9skj94r	58	42	deaths	death	NNS
cord-291400-o9skj94r	58	43	caused	cause	VBN
cord-291400-o9skj94r	58	44	by	by	IN
cord-291400-o9skj94r	58	45	all	all	DT
cord-291400-o9skj94r	58	46	other	other	JJ
cord-291400-o9skj94r	58	47	pathogens	pathogen	NNS
cord-291400-o9skj94r	58	48	[	[	-LRB-
cord-291400-o9skj94r	58	49	30	30	CD
cord-291400-o9skj94r	58	50	]	]	-RRB-
cord-291400-o9skj94r	58	51	.	.	.
cord-291400-o9skj94r	59	1	It	-PRON-	PRP
cord-291400-o9skj94r	59	2	seems	seem	VBZ
cord-291400-o9skj94r	59	3	logical	logical	JJ
cord-291400-o9skj94r	59	4	that	that	IN
cord-291400-o9skj94r	59	5	the	the	DT
cord-291400-o9skj94r	59	6	changes	change	NNS
cord-291400-o9skj94r	59	7	in	in	IN
cord-291400-o9skj94r	59	8	the	the	DT
cord-291400-o9skj94r	59	9	treatment	treatment	NN
cord-291400-o9skj94r	59	10	of	of	IN
cord-291400-o9skj94r	59	11	CAP	cap	NN
cord-291400-o9skj94r	59	12	that	that	WDT
cord-291400-o9skj94r	59	13	result	result	VBP
cord-291400-o9skj94r	59	14	in	in	IN
cord-291400-o9skj94r	59	15	more	more	RBR
cord-291400-o9skj94r	59	16	favorable	favorable	JJ
cord-291400-o9skj94r	59	17	outcomes	outcome	NNS
cord-291400-o9skj94r	59	18	also	also	RB
cord-291400-o9skj94r	59	19	would	would	MD
cord-291400-o9skj94r	59	20	be	be	VB
cord-291400-o9skj94r	59	21	beneficial	beneficial	JJ
cord-291400-o9skj94r	59	22	in	in	IN
cord-291400-o9skj94r	59	23	patients	patient	NNS
cord-291400-o9skj94r	59	24	with	with	IN
cord-291400-o9skj94r	59	25	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	59	26	pneumonia	pneumonia	NN
cord-291400-o9skj94r	59	27	.	.	.
cord-291400-o9skj94r	60	1	Changes	change	NNS
cord-291400-o9skj94r	60	2	that	that	WDT
cord-291400-o9skj94r	60	3	have	have	VBP
cord-291400-o9skj94r	60	4	been	be	VBN
cord-291400-o9skj94r	60	5	associated	associate	VBN
cord-291400-o9skj94r	60	6	with	with	IN
cord-291400-o9skj94r	60	7	improvements	improvement	NNS
cord-291400-o9skj94r	60	8	in	in	IN
cord-291400-o9skj94r	60	9	CFR	CFR	NNP
cord-291400-o9skj94r	60	10	in	in	IN
cord-291400-o9skj94r	60	11	some	some	DT
cord-291400-o9skj94r	60	12	series	series	NN
cord-291400-o9skj94r	60	13	of	of	IN
cord-291400-o9skj94r	60	14	patients	patient	NNS
cord-291400-o9skj94r	60	15	with	with	IN
cord-291400-o9skj94r	60	16	CAP	CAP	NNP
cord-291400-o9skj94r	60	17	include	include	VBP
cord-291400-o9skj94r	60	18	more	more	RBR
cord-291400-o9skj94r	60	19	rapid	rapid	JJ
cord-291400-o9skj94r	60	20	antibiotic	antibiotic	JJ
cord-291400-o9skj94r	60	21	delivery	delivery	NN
cord-291400-o9skj94r	60	22	[	[	-LRB-
cord-291400-o9skj94r	60	23	31	31	CD
cord-291400-o9skj94r	60	24	]	]	-RRB-
cord-291400-o9skj94r	60	25	,	,	,
cord-291400-o9skj94r	60	26	combination	combination	NN
cord-291400-o9skj94r	60	27	therapy	therapy	NN
cord-291400-o9skj94r	60	28	with	with	IN
cord-291400-o9skj94r	60	29	a	a	DT
cord-291400-o9skj94r	60	30	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	60	31	with	with	IN
cord-291400-o9skj94r	60	32	good	good	JJ
cord-291400-o9skj94r	60	33	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	60	34	activity	activity	NN
cord-291400-o9skj94r	60	35	and	and	CC
cord-291400-o9skj94r	60	36	macrolide	macrolide	NN
cord-291400-o9skj94r	60	37	(	(	-LRB-
cord-291400-o9skj94r	60	38	versus	versus	IN
cord-291400-o9skj94r	60	39	the	the	DT
cord-291400-o9skj94r	60	40	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	60	41	alone	alone	RB
cord-291400-o9skj94r	60	42	)	)	-RRB-
cord-291400-o9skj94r	60	43	,	,	,
cord-291400-o9skj94r	60	44	and	and	CC
cord-291400-o9skj94r	60	45	therapy	therapy	NN
cord-291400-o9skj94r	60	46	with	with	IN
cord-291400-o9skj94r	60	47	a	a	DT
cord-291400-o9skj94r	60	48	fluoroquinolone	fluoroquinolone	NN
cord-291400-o9skj94r	60	49	(	(	-LRB-
cord-291400-o9skj94r	60	50	ciprofloxacin	ciprofloxacin	NN
cord-291400-o9skj94r	60	51	;	;	:
cord-291400-o9skj94r	60	52	versus	versus	IN
cord-291400-o9skj94r	60	53	a	a	DT
cord-291400-o9skj94r	60	54	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	60	55	alone	alone	RB
cord-291400-o9skj94r	60	56	)	)	-RRB-
cord-291400-o9skj94r	60	57	[	[	-LRB-
cord-291400-o9skj94r	60	58	32	32	CD
cord-291400-o9skj94r	60	59	]	]	-RRB-
cord-291400-o9skj94r	60	60	.	.	.
cord-291400-o9skj94r	61	1	Culture	culture	NN
cord-291400-o9skj94r	61	2	of	of	IN
cord-291400-o9skj94r	61	3	S	S	NNP
cord-291400-o9skj94r	61	4	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	61	5	from	from	IN
cord-291400-o9skj94r	61	6	a	a	DT
cord-291400-o9skj94r	61	7	normally	normally	RB
cord-291400-o9skj94r	61	8	sterile	sterile	JJ
cord-291400-o9skj94r	61	9	body	body	NN
cord-291400-o9skj94r	61	10	fluid	fluid	NN
cord-291400-o9skj94r	61	11	(	(	-LRB-
cord-291400-o9skj94r	61	12	blood	blood	NN
cord-291400-o9skj94r	61	13	pleural	pleural	NN
cord-291400-o9skj94r	61	14	fluid	fluid	NN
cord-291400-o9skj94r	61	15	)	)	-RRB-
cord-291400-o9skj94r	61	16	in	in	IN
cord-291400-o9skj94r	61	17	a	a	DT
cord-291400-o9skj94r	61	18	patient	patient	NN
cord-291400-o9skj94r	61	19	with	with	IN
cord-291400-o9skj94r	61	20	an	an	DT
cord-291400-o9skj94r	61	21	acute	acute	JJ
cord-291400-o9skj94r	61	22	pneumonia	pneumonia	NN
cord-291400-o9skj94r	61	23	usually	usually	RB
cord-291400-o9skj94r	61	24	is	be	VBZ
cord-291400-o9skj94r	61	25	accepted	accept	VBN
cord-291400-o9skj94r	61	26	as	as	IN
cord-291400-o9skj94r	61	27	definite	definite	JJ
cord-291400-o9skj94r	61	28	sign	sign	NN
cord-291400-o9skj94r	61	29	of	of	IN
cord-291400-o9skj94r	61	30	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	61	31	pneumonia	pneumonia	NN
cord-291400-o9skj94r	61	32	[	[	-LRB-
cord-291400-o9skj94r	61	33	33	33	CD
cord-291400-o9skj94r	61	34	,	,	,
cord-291400-o9skj94r	61	35	34	34	CD
cord-291400-o9skj94r	61	36	]	]	-RRB-
cord-291400-o9skj94r	61	37	.	.	.
cord-291400-o9skj94r	62	1	There	there	EX
cord-291400-o9skj94r	62	2	is	be	VBZ
cord-291400-o9skj94r	62	3	some	some	DT
cord-291400-o9skj94r	62	4	debate	debate	NN
cord-291400-o9skj94r	62	5	as	as	IN
cord-291400-o9skj94r	62	6	to	to	IN
cord-291400-o9skj94r	62	7	the	the	DT
cord-291400-o9skj94r	62	8	value	value	NN
cord-291400-o9skj94r	62	9	of	of	IN
cord-291400-o9skj94r	62	10	culturing	culture	VBG
cord-291400-o9skj94r	62	11	S	s	NN
cord-291400-o9skj94r	62	12	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	62	13	from	from	IN
cord-291400-o9skj94r	62	14	expectorated	expectorated	JJ
cord-291400-o9skj94r	62	15	sputum	sputum	NN
cord-291400-o9skj94r	62	16	even	even	RB
cord-291400-o9skj94r	62	17	with	with	IN
cord-291400-o9skj94r	62	18	a	a	DT
cord-291400-o9skj94r	62	19	compatible	compatible	JJ
cord-291400-o9skj94r	62	20	gram	gram	NN
cord-291400-o9skj94r	62	21	stain	stain	NN
cord-291400-o9skj94r	62	22	,	,	,
cord-291400-o9skj94r	62	23	although	although	IN
cord-291400-o9skj94r	62	24	clinicians	clinician	NNS
cord-291400-o9skj94r	62	25	with	with	IN
cord-291400-o9skj94r	62	26	experience	experience	NN
cord-291400-o9skj94r	62	27	in	in	IN
cord-291400-o9skj94r	62	28	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	62	29	pneumonia	pneumonia	NN
cord-291400-o9skj94r	62	30	value	value	NN
cord-291400-o9skj94r	62	31	the	the	DT
cord-291400-o9skj94r	62	32	information	information	NN
cord-291400-o9skj94r	62	33	provided	provide	VBN
cord-291400-o9skj94r	62	34	by	by	IN
cord-291400-o9skj94r	62	35	high	high	JJ
cord-291400-o9skj94r	62	36	-	-	HYPH
cord-291400-o9skj94r	62	37	quality	quality	NN
cord-291400-o9skj94r	62	38	pulmonary	pulmonary	JJ
cord-291400-o9skj94r	62	39	secretions	secretion	NNS
cord-291400-o9skj94r	62	40	[	[	-LRB-
cord-291400-o9skj94r	62	41	35	35	CD
cord-291400-o9skj94r	62	42	]	]	-RRB-
cord-291400-o9skj94r	62	43	.	.	.
cord-291400-o9skj94r	63	1	A	a	DT
cord-291400-o9skj94r	63	2	rapid	rapid	JJ
cord-291400-o9skj94r	63	3	S	S	NNP
cord-291400-o9skj94r	63	4	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	63	5	urinary	urinary	JJ
cord-291400-o9skj94r	63	6	antigen	antigen	NN
cord-291400-o9skj94r	63	7	has	have	VBZ
cord-291400-o9skj94r	63	8	been	be	VBN
cord-291400-o9skj94r	63	9	evaluated	evaluate	VBN
cord-291400-o9skj94r	63	10	[	[	-LRB-
cord-291400-o9skj94r	63	11	36	36	CD
cord-291400-o9skj94r	63	12	,	,	,
cord-291400-o9skj94r	63	13	37	37	CD
cord-291400-o9skj94r	63	14	]	]	-RRB-
cord-291400-o9skj94r	63	15	and	and	CC
cord-291400-o9skj94r	63	16	shown	show	VBN
cord-291400-o9skj94r	63	17	to	to	TO
cord-291400-o9skj94r	63	18	have	have	VB
cord-291400-o9skj94r	63	19	good	good	JJ
cord-291400-o9skj94r	63	20	specificity	specificity	NN
cord-291400-o9skj94r	63	21	in	in	IN
cord-291400-o9skj94r	63	22	the	the	DT
cord-291400-o9skj94r	63	23	adult	adult	NN
cord-291400-o9skj94r	63	24	population	population	NN
cord-291400-o9skj94r	63	25	(	(	-LRB-
cord-291400-o9skj94r	63	26	[	[	-LRB-
cord-291400-o9skj94r	63	27	95	95	CD
cord-291400-o9skj94r	63	28	%	%	NN
cord-291400-o9skj94r	63	29	in	in	IN
cord-291400-o9skj94r	63	30	most	most	JJS
cord-291400-o9skj94r	63	31	studies	study	NNS
cord-291400-o9skj94r	63	32	)	)	-RRB-
cord-291400-o9skj94r	63	33	and	and	CC
cord-291400-o9skj94r	63	34	reasonable	reasonable	JJ
cord-291400-o9skj94r	63	35	sensitivity	sensitivity	NN
cord-291400-o9skj94r	63	36	(	(	-LRB-
cord-291400-o9skj94r	63	37	70%-80	70%-80	CD
cord-291400-o9skj94r	63	38	%	%	NN
cord-291400-o9skj94r	63	39	in	in	IN
cord-291400-o9skj94r	63	40	most	most	JJS
cord-291400-o9skj94r	63	41	studies	study	NNS
cord-291400-o9skj94r	63	42	)	)	-RRB-
cord-291400-o9skj94r	63	43	.	.	.
cord-291400-o9skj94r	64	1	The	the	DT
cord-291400-o9skj94r	64	2	test	test	NN
cord-291400-o9skj94r	64	3	was	be	VBD
cord-291400-o9skj94r	64	4	too	too	RB
cord-291400-o9skj94r	64	5	sensitive	sensitive	JJ
cord-291400-o9skj94r	64	6	in	in	IN
cord-291400-o9skj94r	64	7	heavily	heavily	RB
cord-291400-o9skj94r	64	8	colonized	colonize	VBN
cord-291400-o9skj94r	64	9	children	child	NNS
cord-291400-o9skj94r	64	10	and	and	CC
cord-291400-o9skj94r	64	11	could	could	MD
cord-291400-o9skj94r	64	12	not	not	RB
cord-291400-o9skj94r	64	13	discriminate	discriminate	VB
cord-291400-o9skj94r	64	14	among	among	IN
cord-291400-o9skj94r	64	15	infected	infected	JJ
cord-291400-o9skj94r	64	16	or	or	CC
cord-291400-o9skj94r	64	17	colonized	colonize	VBN
cord-291400-o9skj94r	64	18	children	child	NNS
cord-291400-o9skj94r	64	19	in	in	IN
cord-291400-o9skj94r	64	20	underdeveloped	underdeveloped	JJ
cord-291400-o9skj94r	64	21	countries	country	NNS
cord-291400-o9skj94r	64	22	[	[	-LRB-
cord-291400-o9skj94r	64	23	38	38	CD
cord-291400-o9skj94r	64	24	]	]	-RRB-
cord-291400-o9skj94r	64	25	.	.	.
cord-291400-o9skj94r	65	1	A	a	DT
cord-291400-o9skj94r	65	2	study	study	NN
cord-291400-o9skj94r	65	3	from	from	IN
cord-291400-o9skj94r	65	4	Spain	Spain	NNP
cord-291400-o9skj94r	65	5	studied	study	VBD
cord-291400-o9skj94r	65	6	452	452	CD
cord-291400-o9skj94r	65	7	patients	patient	NNS
cord-291400-o9skj94r	65	8	who	who	WP
cord-291400-o9skj94r	65	9	were	be	VBD
cord-291400-o9skj94r	65	10	hospitalized	hospitalize	VBN
cord-291400-o9skj94r	65	11	with	with	IN
cord-291400-o9skj94r	65	12	acute	acute	JJ
cord-291400-o9skj94r	65	13	CAP	cap	NN
cord-291400-o9skj94r	65	14	in	in	IN
cord-291400-o9skj94r	65	15	whom	whom	WP
cord-291400-o9skj94r	65	16	a	a	DT
cord-291400-o9skj94r	65	17	S	S	NNP
cord-291400-o9skj94r	65	18	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	65	19	urinary	urinary	JJ
cord-291400-o9skj94r	65	20	antigen	antigen	NN
cord-291400-o9skj94r	65	21	(	(	-LRB-
cord-291400-o9skj94r	65	22	SpUA	SpUA	NNP
cord-291400-o9skj94r	65	23	)	)	-RRB-
cord-291400-o9skj94r	65	24	test	test	NN
cord-291400-o9skj94r	65	25	was	be	VBD
cord-291400-o9skj94r	65	26	performed	perform	VBN
cord-291400-o9skj94r	65	27	[	[	-LRB-
cord-291400-o9skj94r	65	28	39	39	CD
cord-291400-o9skj94r	65	29	]	]	-RRB-
cord-291400-o9skj94r	65	30	.	.	.
cord-291400-o9skj94r	66	1	Pneumococci	pneumococcus	NNS
cord-291400-o9skj94r	66	2	were	be	VBD
cord-291400-o9skj94r	66	3	found	find	VBN
cord-291400-o9skj94r	66	4	in	in	IN
cord-291400-o9skj94r	66	5	cultures	culture	NNS
cord-291400-o9skj94r	66	6	from	from	IN
cord-291400-o9skj94r	66	7	only	only	RB
cord-291400-o9skj94r	66	8	27	27	CD
cord-291400-o9skj94r	66	9	patients	patient	NNS
cord-291400-o9skj94r	66	10	(	(	-LRB-
cord-291400-o9skj94r	66	11	7	7	CD
cord-291400-o9skj94r	66	12	%	%	NN
cord-291400-o9skj94r	66	13	;	;	,
cord-291400-o9skj94r	66	14	half	half	NN
cord-291400-o9skj94r	66	15	from	from	IN
cord-291400-o9skj94r	66	16	blood	blood	NN
cord-291400-o9skj94r	66	17	,	,	,
cord-291400-o9skj94r	66	18	half	half	NN
cord-291400-o9skj94r	66	19	from	from	IN
cord-291400-o9skj94r	66	20	sputum	sputum	NN
cord-291400-o9skj94r	66	21	)	)	-RRB-
cord-291400-o9skj94r	66	22	.	.	.
cord-291400-o9skj94r	67	1	The	the	DT
cord-291400-o9skj94r	67	2	SpUA	spua	NN
cord-291400-o9skj94r	67	3	test	test	NN
cord-291400-o9skj94r	67	4	was	be	VBD
cord-291400-o9skj94r	67	5	positive	positive	JJ
cord-291400-o9skj94r	67	6	in	in	IN
cord-291400-o9skj94r	67	7	19	19	CD
cord-291400-o9skj94r	67	8	of	of	IN
cord-291400-o9skj94r	67	9	27	27	CD
cord-291400-o9skj94r	67	10	patients	patient	NNS
cord-291400-o9skj94r	67	11	with	with	IN
cord-291400-o9skj94r	67	12	positive	positive	JJ
cord-291400-o9skj94r	67	13	cultures	culture	NNS
cord-291400-o9skj94r	67	14	(	(	-LRB-
cord-291400-o9skj94r	67	15	70	70	CD
cord-291400-o9skj94r	67	16	%	%	NN
cord-291400-o9skj94r	67	17	)	)	-RRB-
cord-291400-o9skj94r	67	18	;	;	:
cord-291400-o9skj94r	67	19	however	however	RB
cord-291400-o9skj94r	67	20	,	,	,
cord-291400-o9skj94r	67	21	an	an	DT
cord-291400-o9skj94r	67	22	additional	additional	JJ
cord-291400-o9skj94r	67	23	85	85	CD
cord-291400-o9skj94r	67	24	patients	patient	NNS
cord-291400-o9skj94r	67	25	had	have	VBD
cord-291400-o9skj94r	67	26	positive	positive	JJ
cord-291400-o9skj94r	67	27	SpUA	spua	NN
cord-291400-o9skj94r	67	28	tests	test	NNS
cord-291400-o9skj94r	67	29	with	with	IN
cord-291400-o9skj94r	67	30	cultures	culture	NNS
cord-291400-o9skj94r	67	31	that	that	WDT
cord-291400-o9skj94r	67	32	were	be	VBD
cord-291400-o9skj94r	67	33	negative	negative	JJ
cord-291400-o9skj94r	67	34	for	for	IN
cord-291400-o9skj94r	67	35	pneumococcus	pneumococcus	NNP
cord-291400-o9skj94r	67	36	.	.	.
cord-291400-o9skj94r	68	1	Because	because	IN
cord-291400-o9skj94r	68	2	the	the	DT
cord-291400-o9skj94r	68	3	specificity	specificity	NN
cord-291400-o9skj94r	68	4	has	have	VBZ
cord-291400-o9skj94r	68	5	been	be	VBN
cord-291400-o9skj94r	68	6	reported	report	VBN
cord-291400-o9skj94r	68	7	to	to	TO
cord-291400-o9skj94r	68	8	be	be	VB
cord-291400-o9skj94r	68	9	greater	great	JJR
cord-291400-o9skj94r	68	10	than	than	IN
cord-291400-o9skj94r	68	11	95	95	CD
cord-291400-o9skj94r	68	12	%	%	NN
cord-291400-o9skj94r	68	13	in	in	IN
cord-291400-o9skj94r	68	14	adults	adult	NNS
cord-291400-o9skj94r	68	15	,	,	,
cord-291400-o9skj94r	68	16	most	most	JJS
cord-291400-o9skj94r	68	17	of	of	IN
cord-291400-o9skj94r	68	18	these	these	DT
cord-291400-o9skj94r	68	19	patients	patient	NNS
cord-291400-o9skj94r	68	20	also	also	RB
cord-291400-o9skj94r	68	21	had	have	VBD
cord-291400-o9skj94r	68	22	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	68	23	pneumonia	pneumonia	NN
cord-291400-o9skj94r	68	24	.	.	.
cord-291400-o9skj94r	69	1	In	in	IN
cord-291400-o9skj94r	69	2	this	this	DT
cord-291400-o9skj94r	69	3	study	study	NN
cord-291400-o9skj94r	69	4	,	,	,
cord-291400-o9skj94r	69	5	112	112	CD
cord-291400-o9skj94r	69	6	of	of	IN
cord-291400-o9skj94r	69	7	452	452	CD
cord-291400-o9skj94r	69	8	patients	patient	NNS
cord-291400-o9skj94r	69	9	(	(	-LRB-
cord-291400-o9skj94r	69	10	25	25	CD
cord-291400-o9skj94r	69	11	%	%	NN
cord-291400-o9skj94r	69	12	)	)	-RRB-
cord-291400-o9skj94r	69	13	would	would	MD
cord-291400-o9skj94r	69	14	have	have	VB
cord-291400-o9skj94r	69	15	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	69	16	pneumonia	pneumonia	NN
cord-291400-o9skj94r	69	17	,	,	,
cord-291400-o9skj94r	69	18	a	a	DT
cord-291400-o9skj94r	69	19	proportion	proportion	NN
cord-291400-o9skj94r	69	20	of	of	IN
cord-291400-o9skj94r	69	21	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	69	22	pneumonia	pneumonia	NN
cord-291400-o9skj94r	69	23	cases	case	NNS
cord-291400-o9skj94r	69	24	that	that	WDT
cord-291400-o9skj94r	69	25	is	be	VBZ
cord-291400-o9skj94r	69	26	similar	similar	JJ
cord-291400-o9skj94r	69	27	to	to	IN
cord-291400-o9skj94r	69	28	the	the	DT
cord-291400-o9skj94r	69	29	proportion	proportion	NN
cord-291400-o9skj94r	69	30	in	in	IN
cord-291400-o9skj94r	69	31	other	other	JJ
cord-291400-o9skj94r	69	32	large	large	JJ
cord-291400-o9skj94r	69	33	series	series	NN
cord-291400-o9skj94r	69	34	of	of	IN
cord-291400-o9skj94r	69	35	hospitalized	hospitalize	VBN
cord-291400-o9skj94r	69	36	cases	case	NNS
cord-291400-o9skj94r	69	37	of	of	IN
cord-291400-o9skj94r	69	38	CAP	CAP	NNP
cord-291400-o9skj94r	69	39	.	.	.
cord-291400-o9skj94r	70	1	The	the	DT
cord-291400-o9skj94r	70	2	sensitivity	sensitivity	NN
cord-291400-o9skj94r	70	3	of	of	IN
cord-291400-o9skj94r	70	4	the	the	DT
cord-291400-o9skj94r	70	5	SpUA	spua	NN
cord-291400-o9skj94r	70	6	test	test	NN
cord-291400-o9skj94r	70	7	would	would	MD
cord-291400-o9skj94r	70	8	be	be	VB
cord-291400-o9skj94r	70	9	104	104	CD
cord-291400-o9skj94r	70	10	of	of	IN
cord-291400-o9skj94r	70	11	112	112	CD
cord-291400-o9skj94r	70	12	patients	patient	NNS
cord-291400-o9skj94r	70	13	(	(	-LRB-
cord-291400-o9skj94r	70	14	93	93	CD
cord-291400-o9skj94r	70	15	%	%	NN
cord-291400-o9skj94r	70	16	)	)	-RRB-
cord-291400-o9skj94r	70	17	or	or	CC
cord-291400-o9skj94r	70	18	at	at	IN
cord-291400-o9skj94r	70	19	least	least	JJS
cord-291400-o9skj94r	70	20	would	would	MD
cord-291400-o9skj94r	70	21	be	be	VB
cord-291400-o9skj94r	70	22	four	four	CD
cord-291400-o9skj94r	70	23	times	time	NNS
cord-291400-o9skj94r	70	24	greater	great	JJR
cord-291400-o9skj94r	70	25	than	than	IN
cord-291400-o9skj94r	70	26	the	the	DT
cord-291400-o9skj94r	70	27	combination	combination	NN
cord-291400-o9skj94r	70	28	of	of	IN
cord-291400-o9skj94r	70	29	cultures	culture	NNS
cord-291400-o9skj94r	70	30	of	of	IN
cord-291400-o9skj94r	70	31	sputum	sputum	NN
cord-291400-o9skj94r	70	32	and	and	CC
cord-291400-o9skj94r	70	33	blood	blood	NN
cord-291400-o9skj94r	70	34	(	(	-LRB-
cord-291400-o9skj94r	70	35	27	27	CD
cord-291400-o9skj94r	70	36	of	of	IN
cord-291400-o9skj94r	70	37	112	112	CD
cord-291400-o9skj94r	70	38	patients	patient	NNS
cord-291400-o9skj94r	70	39	[	[	-LRB-
cord-291400-o9skj94r	70	40	24	24	CD
cord-291400-o9skj94r	70	41	%	%	NN
cord-291400-o9skj94r	70	42	]	]	-RRB-
cord-291400-o9skj94r	70	43	)	)	-RRB-
cord-291400-o9skj94r	70	44	.	.	.
cord-291400-o9skj94r	71	1	Cultures	culture	NNS
cord-291400-o9skj94r	71	2	still	still	RB
cord-291400-o9skj94r	71	3	would	would	MD
cord-291400-o9skj94r	71	4	be	be	VB
cord-291400-o9skj94r	71	5	important	important	JJ
cord-291400-o9skj94r	71	6	in	in	IN
cord-291400-o9skj94r	71	7	determining	determine	VBG
cord-291400-o9skj94r	71	8	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	71	9	susceptibility	susceptibility	NN
cord-291400-o9skj94r	71	10	.	.	.
cord-291400-o9skj94r	72	1	Several	several	JJ
cord-291400-o9skj94r	72	2	retrospective	retrospective	JJ
cord-291400-o9skj94r	72	3	studies	study	NNS
cord-291400-o9skj94r	72	4	suggest	suggest	VBP
cord-291400-o9skj94r	72	5	that	that	IN
cord-291400-o9skj94r	72	6	monotherapy	monotherapy	IN
cord-291400-o9skj94r	72	7	with	with	IN
cord-291400-o9skj94r	72	8	an	an	DT
cord-291400-o9skj94r	72	9	effective	effective	JJ
cord-291400-o9skj94r	72	10	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	72	11	is	be	VBZ
cord-291400-o9skj94r	72	12	not	not	RB
cord-291400-o9skj94r	72	13	adequate	adequate	JJ
cord-291400-o9skj94r	72	14	treatment	treatment	NN
cord-291400-o9skj94r	72	15	for	for	IN
cord-291400-o9skj94r	72	16	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	72	17	pneumonia	pneumonia	NN
cord-291400-o9skj94r	72	18	.	.	.
cord-291400-o9skj94r	73	1	Mufson	Mufson	NNP
cord-291400-o9skj94r	73	2	and	and	CC
cord-291400-o9skj94r	73	3	Stanek	Stanek	NNP
cord-291400-o9skj94r	73	4	[	[	-LRB-
cord-291400-o9skj94r	73	5	5	5	CD
cord-291400-o9skj94r	73	6	]	]	-RRB-
cord-291400-o9skj94r	73	7	reported	report	VBN
cord-291400-o9skj94r	73	8	on	on	IN
cord-291400-o9skj94r	73	9	423	423	CD
cord-291400-o9skj94r	73	10	patients	patient	NNS
cord-291400-o9skj94r	73	11	with	with	IN
cord-291400-o9skj94r	73	12	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	73	13	bacteremia	bacteremia	NN
cord-291400-o9skj94r	73	14	in	in	IN
cord-291400-o9skj94r	73	15	Huntington	Huntington	NNP
cord-291400-o9skj94r	73	16	,	,	,
cord-291400-o9skj94r	73	17	West	West	NNP
cord-291400-o9skj94r	73	18	Virginia	Virginia	NNP
cord-291400-o9skj94r	73	19	over	over	IN
cord-291400-o9skj94r	73	20	20	20	CD
cord-291400-o9skj94r	73	21	years	year	NNS
cord-291400-o9skj94r	73	22	.	.	.
cord-291400-o9skj94r	74	1	The	the	DT
cord-291400-o9skj94r	74	2	data	datum	NNS
cord-291400-o9skj94r	74	3	were	be	VBD
cord-291400-o9skj94r	74	4	analyzed	analyze	VBN
cord-291400-o9skj94r	74	5	in	in	IN
cord-291400-o9skj94r	74	6	5-year	5-year	CD
cord-291400-o9skj94r	74	7	periods	period	NNS
cord-291400-o9skj94r	74	8	.	.	.
cord-291400-o9skj94r	75	1	Overall	overall	RB
cord-291400-o9skj94r	75	2	,	,	,
cord-291400-o9skj94r	75	3	the	the	DT
cord-291400-o9skj94r	75	4	incidence	incidence	NN
cord-291400-o9skj94r	75	5	of	of	IN
cord-291400-o9skj94r	75	6	pneumococcall	pneumococcall	NNP
cord-291400-o9skj94r	75	7	bacteremia	bacteremia	NN
cord-291400-o9skj94r	75	8	increased	increase	VBD
cord-291400-o9skj94r	75	9	,	,	,
cord-291400-o9skj94r	75	10	and	and	CC
cord-291400-o9skj94r	75	11	the	the	DT
cord-291400-o9skj94r	75	12	CFR	CFR	NNP
cord-291400-o9skj94r	75	13	decreased	decrease	VBD
cord-291400-o9skj94r	75	14	.	.	.
cord-291400-o9skj94r	76	1	In	in	IN
cord-291400-o9skj94r	76	2	each	each	DT
cord-291400-o9skj94r	76	3	5-year	5-year	CD
cord-291400-o9skj94r	76	4	period	period	NN
cord-291400-o9skj94r	76	5	,	,	,
cord-291400-o9skj94r	76	6	a	a	DT
cord-291400-o9skj94r	76	7	regimen	regimen	NN
cord-291400-o9skj94r	76	8	including	include	VBG
cord-291400-o9skj94r	76	9	a	a	DT
cord-291400-o9skj94r	76	10	macrolide	macrolide	NN
cord-291400-o9skj94r	76	11	and	and	CC
cord-291400-o9skj94r	76	12	b	b	NN
cord-291400-o9skj94r	76	13	-	-	HYPH
cord-291400-o9skj94r	76	14	lactam	lactam	NN
cord-291400-o9skj94r	76	15	resulted	result	VBD
cord-291400-o9skj94r	76	16	in	in	IN
cord-291400-o9skj94r	76	17	lower	low	JJR
cord-291400-o9skj94r	76	18	CFR	CFR	NNP
cord-291400-o9skj94r	76	19	than	than	IN
cord-291400-o9skj94r	76	20	did	do	VBD
cord-291400-o9skj94r	76	21	regimens	regimen	NNS
cord-291400-o9skj94r	76	22	involving	involve	VBG
cord-291400-o9skj94r	76	23	a	a	DT
cord-291400-o9skj94r	76	24	b	b	NN
cord-291400-o9skj94r	76	25	-	-	HYPH
cord-291400-o9skj94r	76	26	lactam	lactam	NN
cord-291400-o9skj94r	76	27	alone	alone	RB
cord-291400-o9skj94r	76	28	or	or	CC
cord-291400-o9skj94r	76	29	two	two	CD
cord-291400-o9skj94r	76	30	antibiotics	antibiotic	NNS
cord-291400-o9skj94r	76	31	(	(	-LRB-
cord-291400-o9skj94r	76	32	excluding	exclude	VBG
cord-291400-o9skj94r	76	33	macrolides	macrolide	NNS
cord-291400-o9skj94r	76	34	)	)	-RRB-
cord-291400-o9skj94r	76	35	.	.	.
cord-291400-o9skj94r	77	1	No	no	DT
cord-291400-o9skj94r	77	2	specifics	specific	NNS
cord-291400-o9skj94r	77	3	were	be	VBD
cord-291400-o9skj94r	77	4	provided	provide	VBN
cord-291400-o9skj94r	77	5	on	on	IN
cord-291400-o9skj94r	77	6	the	the	DT
cord-291400-o9skj94r	77	7	timing	timing	NN
cord-291400-o9skj94r	77	8	of	of	IN
cord-291400-o9skj94r	77	9	the	the	DT
cord-291400-o9skj94r	77	10	initial	initial	JJ
cord-291400-o9skj94r	77	11	dose	dose	NN
cord-291400-o9skj94r	77	12	and	and	CC
cord-291400-o9skj94r	77	13	changes	change	NNS
cord-291400-o9skj94r	77	14	in	in	IN
cord-291400-o9skj94r	77	15	therapy	therapy	NN
cord-291400-o9skj94r	77	16	.	.	.
cord-291400-o9skj94r	78	1	Fluoroquinolones	fluoroquinolone	NNS
cord-291400-o9skj94r	78	2	were	be	VBD
cord-291400-o9skj94r	78	3	used	use	VBN
cord-291400-o9skj94r	78	4	infrequently	infrequently	RB
cord-291400-o9skj94r	78	5	.	.	.
cord-291400-o9skj94r	79	1	Although	although	IN
cord-291400-o9skj94r	79	2	this	this	DT
cord-291400-o9skj94r	79	3	study	study	NN
cord-291400-o9skj94r	79	4	was	be	VBD
cord-291400-o9skj94r	79	5	retrospective	retrospective	JJ
cord-291400-o9skj94r	79	6	and	and	CC
cord-291400-o9skj94r	79	7	did	do	VBD
cord-291400-o9skj94r	79	8	not	not	RB
cord-291400-o9skj94r	79	9	control	control	VB
cord-291400-o9skj94r	79	10	for	for	IN
cord-291400-o9skj94r	79	11	severity	severity	NN
cord-291400-o9skj94r	79	12	of	of	IN
cord-291400-o9skj94r	79	13	illness	illness	NN
cord-291400-o9skj94r	79	14	,	,	,
cord-291400-o9skj94r	79	15	it	-PRON-	PRP
cord-291400-o9skj94r	79	16	may	may	MD
cord-291400-o9skj94r	79	17	have	have	VB
cord-291400-o9skj94r	79	18	offered	offer	VBN
cord-291400-o9skj94r	79	19	the	the	DT
cord-291400-o9skj94r	79	20	first	first	JJ
cord-291400-o9skj94r	79	21	clue	clue	NN
cord-291400-o9skj94r	79	22	that	that	IN
cord-291400-o9skj94r	79	23	monotherapy	monotherapy	NN
cord-291400-o9skj94r	79	24	of	of	IN
cord-291400-o9skj94r	79	25	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	79	26	bacteremia	bacteremia	NN
cord-291400-o9skj94r	79	27	with	with	IN
cord-291400-o9skj94r	79	28	a	a	DT
cord-291400-o9skj94r	79	29	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	79	30	is	be	VBZ
cord-291400-o9skj94r	79	31	less	less	RBR
cord-291400-o9skj94r	79	32	efficacious	efficacious	JJ
cord-291400-o9skj94r	79	33	than	than	IN
cord-291400-o9skj94r	79	34	combination	combination	NN
cord-291400-o9skj94r	79	35	therapy	therapy	NN
cord-291400-o9skj94r	79	36	with	with	IN
cord-291400-o9skj94r	79	37	a	a	DT
cord-291400-o9skj94r	79	38	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	79	39	and	and	CC
cord-291400-o9skj94r	79	40	a	a	DT
cord-291400-o9skj94r	79	41	macrolide	macrolide	NN
cord-291400-o9skj94r	79	42	.	.	.
cord-291400-o9skj94r	80	1	Waterer	Waterer	NNP
cord-291400-o9skj94r	80	2	et	et	NNP
cord-291400-o9skj94r	80	3	al	al	NNP
cord-291400-o9skj94r	80	4	[	[	-LRB-
cord-291400-o9skj94r	80	5	6	6	CD
cord-291400-o9skj94r	80	6	]	]	-RRB-
cord-291400-o9skj94r	80	7	reported	report	VBN
cord-291400-o9skj94r	80	8	data	datum	NNS
cord-291400-o9skj94r	80	9	on	on	IN
cord-291400-o9skj94r	80	10	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	80	11	therapy	therapy	NN
cord-291400-o9skj94r	80	12	in	in	IN
cord-291400-o9skj94r	80	13	225	225	CD
cord-291400-o9skj94r	80	14	patients	patient	NNS
cord-291400-o9skj94r	80	15	with	with	IN
cord-291400-o9skj94r	80	16	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	80	17	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	80	18	pneumonia	pneumonia	NN
cord-291400-o9skj94r	80	19	from	from	IN
cord-291400-o9skj94r	80	20	13	13	CD
cord-291400-o9skj94r	80	21	hospitals	hospital	NNS
cord-291400-o9skj94r	80	22	in	in	IN
cord-291400-o9skj94r	80	23	Tennessee	Tennessee	NNP
cord-291400-o9skj94r	80	24	between	between	IN
cord-291400-o9skj94r	80	25	January	January	NNP
cord-291400-o9skj94r	80	26	1996	1996	CD
cord-291400-o9skj94r	80	27	and	and	CC
cord-291400-o9skj94r	80	28	July	July	NNP
cord-291400-o9skj94r	80	29	2000	2000	CD
cord-291400-o9skj94r	80	30	.	.	.
cord-291400-o9skj94r	81	1	Immune	immune	NN
cord-291400-o9skj94r	81	2	-	-	HYPH
cord-291400-o9skj94r	81	3	compromised	compromise	VBN
cord-291400-o9skj94r	81	4	patients	patient	NNS
cord-291400-o9skj94r	81	5	were	be	VBD
cord-291400-o9skj94r	81	6	excluded	exclude	VBN
cord-291400-o9skj94r	81	7	.	.	.
cord-291400-o9skj94r	82	1	Seven	seven	CD
cord-291400-o9skj94r	82	2	patients	patient	NNS
cord-291400-o9skj94r	82	3	with	with	IN
cord-291400-o9skj94r	82	4	S	s	NN
cord-291400-o9skj94r	82	5	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	82	6	isolates	isolate	VBZ
cord-291400-o9skj94r	82	7	resistant	resistant	JJ
cord-291400-o9skj94r	82	8	to	to	IN
cord-291400-o9skj94r	82	9	empiric	empiric	JJ
cord-291400-o9skj94r	82	10	therapy	therapy	NN
cord-291400-o9skj94r	82	11	also	also	RB
cord-291400-o9skj94r	82	12	were	be	VBD
cord-291400-o9skj94r	82	13	excluded	exclude	VBN
cord-291400-o9skj94r	82	14	.	.	.
cord-291400-o9skj94r	83	1	Patients	patient	NNS
cord-291400-o9skj94r	83	2	received	receive	VBD
cord-291400-o9skj94r	83	3	one	one	CD
cord-291400-o9skj94r	83	4	antibiotic	antibiotic	NN
cord-291400-o9skj94r	83	5	active	active	JJ
cord-291400-o9skj94r	83	6	against	against	IN
cord-291400-o9skj94r	83	7	the	the	DT
cord-291400-o9skj94r	83	8	patient	patient	NN
cord-291400-o9skj94r	83	9	's	's	POS
cord-291400-o9skj94r	83	10	isolate	isolate	NN
cord-291400-o9skj94r	83	11	(	(	-LRB-
cord-291400-o9skj94r	83	12	single	single	JJ
cord-291400-o9skj94r	83	13	effective	effective	JJ
cord-291400-o9skj94r	83	14	therapy	therapy	NN
cord-291400-o9skj94r	83	15	[	[	-LRB-
cord-291400-o9skj94r	83	16	SET	set	NN
cord-291400-o9skj94r	83	17	]	]	-RRB-
cord-291400-o9skj94r	83	18	)	)	-RRB-
cord-291400-o9skj94r	83	19	,	,	,
cord-291400-o9skj94r	83	20	two	two	CD
cord-291400-o9skj94r	83	21	effective	effective	JJ
cord-291400-o9skj94r	83	22	antibiotics	antibiotic	NNS
cord-291400-o9skj94r	83	23	(	(	-LRB-
cord-291400-o9skj94r	83	24	dual	dual	JJ
cord-291400-o9skj94r	83	25	effective	effective	JJ
cord-291400-o9skj94r	83	26	therapy	therapy	NN
cord-291400-o9skj94r	83	27	[	[	-LRB-
cord-291400-o9skj94r	83	28	DET	DET	NNP
cord-291400-o9skj94r	83	29	]	]	-RRB-
cord-291400-o9skj94r	83	30	)	)	-RRB-
cord-291400-o9skj94r	83	31	,	,	,
cord-291400-o9skj94r	83	32	or	or	CC
cord-291400-o9skj94r	83	33	more	more	JJR
cord-291400-o9skj94r	83	34	than	than	IN
cord-291400-o9skj94r	83	35	two	two	CD
cord-291400-o9skj94r	83	36	effective	effective	JJ
cord-291400-o9skj94r	83	37	antibiotics	antibiotic	NNS
cord-291400-o9skj94r	83	38	(	(	-LRB-
cord-291400-o9skj94r	83	39	MET	MET	NNP
cord-291400-o9skj94r	83	40	)	)	-RRB-
cord-291400-o9skj94r	83	41	.	.	.
cord-291400-o9skj94r	84	1	Logistic	logistic	JJ
cord-291400-o9skj94r	84	2	regression	regression	NN
cord-291400-o9skj94r	84	3	analysis	analysis	NN
cord-291400-o9skj94r	84	4	was	be	VBD
cord-291400-o9skj94r	84	5	used	use	VBN
cord-291400-o9skj94r	84	6	to	to	TO
cord-291400-o9skj94r	84	7	calculate	calculate	VB
cord-291400-o9skj94r	84	8	the	the	DT
cord-291400-o9skj94r	84	9	odds	odd	NNS
cord-291400-o9skj94r	84	10	ratio	ratio	NN
cord-291400-o9skj94r	84	11	(	(	-LRB-
cord-291400-o9skj94r	84	12	OR	or	CC
cord-291400-o9skj94r	84	13	)	)	-RRB-
cord-291400-o9skj94r	84	14	for	for	IN
cord-291400-o9skj94r	84	15	death	death	NN
cord-291400-o9skj94r	84	16	adjusted	adjust	VBN
cord-291400-o9skj94r	84	17	for	for	IN
cord-291400-o9skj94r	84	18	predicted	predict	VBN
cord-291400-o9skj94r	84	19	mortality	mortality	NN
cord-291400-o9skj94r	84	20	.	.	.
cord-291400-o9skj94r	85	1	Compared	compare	VBN
cord-291400-o9skj94r	85	2	with	with	IN
cord-291400-o9skj94r	85	3	DET	DET	NNP
cord-291400-o9skj94r	85	4	,	,	,
cord-291400-o9skj94r	85	5	the	the	DT
cord-291400-o9skj94r	85	6	OR	OR	NNP
cord-291400-o9skj94r	85	7	for	for	IN
cord-291400-o9skj94r	85	8	SET	set	NN
cord-291400-o9skj94r	85	9	was	be	VBD
cord-291400-o9skj94r	85	10	6.4	6.4	CD
cord-291400-o9skj94r	85	11	(	(	-LRB-
cord-291400-o9skj94r	85	12	95	95	CD
cord-291400-o9skj94r	85	13	%	%	NN
cord-291400-o9skj94r	85	14	confidence	confidence	NN
cord-291400-o9skj94r	85	15	interval	interval	NN
cord-291400-o9skj94r	85	16	[	[	-LRB-
cord-291400-o9skj94r	85	17	CI	CI	NNP
cord-291400-o9skj94r	85	18	]	]	-RRB-
cord-291400-o9skj94r	85	19	,	,	,
cord-291400-o9skj94r	85	20	1.9	1.9	CD
cord-291400-o9skj94r	85	21	-	-	SYM
cord-291400-o9skj94r	85	22	21.7	21.7	CD
cord-291400-o9skj94r	85	23	)	)	-RRB-
cord-291400-o9skj94r	85	24	.	.	.
cord-291400-o9skj94r	86	1	All	all	DT
cord-291400-o9skj94r	86	2	deaths	death	NNS
cord-291400-o9skj94r	86	3	occurred	occur	VBD
cord-291400-o9skj94r	86	4	in	in	IN
cord-291400-o9skj94r	86	5	cases	case	NNS
cord-291400-o9skj94r	86	6	with	with	IN
cord-291400-o9skj94r	86	7	pneumonia	pneumonia	NN
cord-291400-o9skj94r	86	8	severity	severity	NN
cord-291400-o9skj94r	86	9	index	index	NN
cord-291400-o9skj94r	86	10	(	(	-LRB-
cord-291400-o9skj94r	86	11	PSI	PSI	NNP
cord-291400-o9skj94r	86	12	)	)	-RRB-
cord-291400-o9skj94r	86	13	classes	class	NNS
cord-291400-o9skj94r	86	14	IV	IV	NNP
cord-291400-o9skj94r	86	15	and	and	CC
cord-291400-o9skj94r	86	16	V.	V.	NNP
cord-291400-o9skj94r	87	1	Even	even	RB
cord-291400-o9skj94r	87	2	after	after	IN
cord-291400-o9skj94r	87	3	excluding	exclude	VBG
cord-291400-o9skj94r	87	4	deaths	death	NNS
cord-291400-o9skj94r	87	5	that	that	WDT
cord-291400-o9skj94r	87	6	occurred	occur	VBD
cord-291400-o9skj94r	87	7	in	in	IN
cord-291400-o9skj94r	87	8	first	first	JJ
cord-291400-o9skj94r	87	9	48	48	CD
cord-291400-o9skj94r	87	10	hours	hour	NNS
cord-291400-o9skj94r	87	11	of	of	IN
cord-291400-o9skj94r	87	12	hospitalization	hospitalization	NN
cord-291400-o9skj94r	87	13	,	,	,
cord-291400-o9skj94r	87	14	SET	SET	NNP
cord-291400-o9skj94r	87	15	was	be	VBD
cord-291400-o9skj94r	87	16	an	an	DT
cord-291400-o9skj94r	87	17	independent	independent	JJ
cord-291400-o9skj94r	87	18	predictor	predictor	NN
cord-291400-o9skj94r	87	19	of	of	IN
cord-291400-o9skj94r	87	20	death	death	NN
cord-291400-o9skj94r	87	21	(	(	-LRB-
cord-291400-o9skj94r	87	22	OR	or	CC
cord-291400-o9skj94r	87	23	,	,	,
cord-291400-o9skj94r	87	24	4.9	4.9	CD
cord-291400-o9skj94r	87	25	;	;	:
cord-291400-o9skj94r	87	26	95%CI	95%ci	CD
cord-291400-o9skj94r	87	27	1.6	1.6	CD
cord-291400-o9skj94r	87	28	-	-	SYM
cord-291400-o9skj94r	87	29	18.3	18.3	CD
cord-291400-o9skj94r	87	30	)	)	-RRB-
cord-291400-o9skj94r	87	31	.	.	.
cord-291400-o9skj94r	88	1	Analysis	analysis	NN
cord-291400-o9skj94r	88	2	was	be	VBD
cord-291400-o9skj94r	88	3	done	do	VBN
cord-291400-o9skj94r	88	4	to	to	TO
cord-291400-o9skj94r	88	5	evaluate	evaluate	VB
cord-291400-o9skj94r	88	6	coverage	coverage	NN
cord-291400-o9skj94r	88	7	for	for	IN
cord-291400-o9skj94r	88	8	atypical	atypical	JJ
cord-291400-o9skj94r	88	9	pathogens	pathogen	NNS
cord-291400-o9skj94r	88	10	.	.	.
cord-291400-o9skj94r	89	1	The	the	DT
cord-291400-o9skj94r	89	2	CFR	CFR	NNP
cord-291400-o9skj94r	89	3	was	be	VBD
cord-291400-o9skj94r	89	4	9.9	9.9	CD
cord-291400-o9skj94r	89	5	%	%	NN
cord-291400-o9skj94r	89	6	(	(	-LRB-
cord-291400-o9skj94r	89	7	17	17	CD
cord-291400-o9skj94r	89	8	of	of	IN
cord-291400-o9skj94r	89	9	172	172	CD
cord-291400-o9skj94r	89	10	patients	patient	NNS
cord-291400-o9skj94r	89	11	)	)	-RRB-
cord-291400-o9skj94r	89	12	in	in	IN
cord-291400-o9skj94r	89	13	patients	patient	NNS
cord-291400-o9skj94r	89	14	receiving	receive	VBG
cord-291400-o9skj94r	89	15	atypical	atypical	JJ
cord-291400-o9skj94r	89	16	coverage	coverage	NN
cord-291400-o9skj94r	89	17	and	and	CC
cord-291400-o9skj94r	89	18	was	be	VBD
cord-291400-o9skj94r	89	19	22.6	22.6	CD
cord-291400-o9skj94r	89	20	%	%	NN
cord-291400-o9skj94r	89	21	(	(	-LRB-
cord-291400-o9skj94r	89	22	12	12	CD
cord-291400-o9skj94r	89	23	of	of	IN
cord-291400-o9skj94r	89	24	53	53	CD
cord-291400-o9skj94r	89	25	)	)	-RRB-
cord-291400-o9skj94r	89	26	in	in	IN
cord-291400-o9skj94r	89	27	patients	patient	NNS
cord-291400-o9skj94r	89	28	not	not	RB
cord-291400-o9skj94r	89	29	receiving	receive	VBG
cord-291400-o9skj94r	89	30	atypical	atypical	JJ
cord-291400-o9skj94r	89	31	coverage	coverage	NN
cord-291400-o9skj94r	89	32	;	;	:
cord-291400-o9skj94r	89	33	however	however	RB
cord-291400-o9skj94r	89	34	,	,	,
cord-291400-o9skj94r	89	35	the	the	DT
cord-291400-o9skj94r	89	36	predicted	predict	VBN
cord-291400-o9skj94r	89	37	mortality	mortality	NN
cord-291400-o9skj94r	89	38	rate	rate	NN
cord-291400-o9skj94r	89	39	was	be	VBD
cord-291400-o9skj94r	89	40	higher	high	JJR
cord-291400-o9skj94r	89	41	in	in	IN
cord-291400-o9skj94r	89	42	the	the	DT
cord-291400-o9skj94r	89	43	latter	latter	JJ
cord-291400-o9skj94r	89	44	group	group	NN
cord-291400-o9skj94r	89	45	of	of	IN
cord-291400-o9skj94r	89	46	patients	patient	NNS
cord-291400-o9skj94r	89	47	.	.	.
cord-291400-o9skj94r	90	1	Multivariate	multivariate	JJ
cord-291400-o9skj94r	90	2	analysis	analysis	NN
cord-291400-o9skj94r	90	3	did	do	VBD
cord-291400-o9skj94r	90	4	not	not	RB
cord-291400-o9skj94r	90	5	show	show	VB
cord-291400-o9skj94r	90	6	that	that	IN
cord-291400-o9skj94r	90	7	lack	lack	NN
cord-291400-o9skj94r	90	8	of	of	IN
cord-291400-o9skj94r	90	9	atypical	atypical	JJ
cord-291400-o9skj94r	90	10	coverage	coverage	NN
cord-291400-o9skj94r	90	11	was	be	VBD
cord-291400-o9skj94r	90	12	a	a	DT
cord-291400-o9skj94r	90	13	predictor	predictor	NN
cord-291400-o9skj94r	90	14	of	of	IN
cord-291400-o9skj94r	90	15	death	death	NN
cord-291400-o9skj94r	90	16	(	(	-LRB-
cord-291400-o9skj94r	90	17	P	p	NN
cord-291400-o9skj94r	90	18	=	=	SYM
cord-291400-o9skj94r	90	19	0.17	0.17	CD
cord-291400-o9skj94r	90	20	)	)	-RRB-
cord-291400-o9skj94r	90	21	.	.	.
cord-291400-o9skj94r	91	1	The	the	DT
cord-291400-o9skj94r	91	2	investigators	investigator	NNS
cord-291400-o9skj94r	91	3	suggest	suggest	VBP
cord-291400-o9skj94r	91	4	that	that	IN
cord-291400-o9skj94r	91	5	prospective	prospective	JJ
cord-291400-o9skj94r	91	6	studies	study	NNS
cord-291400-o9skj94r	91	7	should	should	MD
cord-291400-o9skj94r	91	8	address	address	VB
cord-291400-o9skj94r	91	9	SET	SET	NNP
cord-291400-o9skj94r	91	10	versus	versus	IN
cord-291400-o9skj94r	91	11	DET	DET	NNP
cord-291400-o9skj94r	91	12	in	in	IN
cord-291400-o9skj94r	91	13	patients	patient	NNS
cord-291400-o9skj94r	91	14	with	with	IN
cord-291400-o9skj94r	91	15	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	91	16	bacteremia	bacteremia	NN
cord-291400-o9skj94r	91	17	in	in	IN
cord-291400-o9skj94r	91	18	PSI	PSI	NNP
cord-291400-o9skj94r	91	19	classes	class	NNS
cord-291400-o9skj94r	91	20	IV	IV	NNP
cord-291400-o9skj94r	91	21	and	and	CC
cord-291400-o9skj94r	91	22	V.	V.	NNP
cord-291400-o9skj94r	91	23	They	-PRON-	PRP
cord-291400-o9skj94r	91	24	state	state	VBP
cord-291400-o9skj94r	91	25	that	that	IN
cord-291400-o9skj94r	91	26	the	the	DT
cord-291400-o9skj94r	91	27	S	S	NNP
cord-291400-o9skj94r	91	28	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	91	29	urinary	urinary	JJ
cord-291400-o9skj94r	91	30	antigen	antigen	NN
cord-291400-o9skj94r	91	31	should	should	MD
cord-291400-o9skj94r	91	32	help	help	VB
cord-291400-o9skj94r	91	33	in	in	IN
cord-291400-o9skj94r	91	34	rapidly	rapidly	RB
cord-291400-o9skj94r	91	35	identifying	identify	VBG
cord-291400-o9skj94r	91	36	the	the	DT
cord-291400-o9skj94r	91	37	subset	subset	NN
cord-291400-o9skj94r	91	38	of	of	IN
cord-291400-o9skj94r	91	39	patients	patient	NNS
cord-291400-o9skj94r	91	40	with	with	IN
cord-291400-o9skj94r	91	41	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	91	42	pneumonia	pneumonia	NN
cord-291400-o9skj94r	91	43	.	.	.
cord-291400-o9skj94r	92	1	Martinez	Martinez	NNP
cord-291400-o9skj94r	92	2	et	et	NNP
cord-291400-o9skj94r	92	3	al	al	NNP
cord-291400-o9skj94r	92	4	[	[	-LRB-
cord-291400-o9skj94r	92	5	7	7	CD
cord-291400-o9skj94r	92	6	]	]	-RRB-
cord-291400-o9skj94r	92	7	performed	perform	VBD
cord-291400-o9skj94r	92	8	a	a	DT
cord-291400-o9skj94r	92	9	retrospective	retrospective	JJ
cord-291400-o9skj94r	92	10	analysis	analysis	NN
cord-291400-o9skj94r	92	11	of	of	IN
cord-291400-o9skj94r	92	12	a	a	DT
cord-291400-o9skj94r	92	13	10-year	10-year	CD
cord-291400-o9skj94r	92	14	(	(	-LRB-
cord-291400-o9skj94r	92	15	1991	1991	CD
cord-291400-o9skj94r	92	16	-	-	SYM
cord-291400-o9skj94r	92	17	2000	2000	CD
cord-291400-o9skj94r	92	18	)	)	-RRB-
cord-291400-o9skj94r	92	19	database	database	NN
cord-291400-o9skj94r	92	20	of	of	IN
cord-291400-o9skj94r	92	21	patients	patient	NNS
cord-291400-o9skj94r	92	22	with	with	IN
cord-291400-o9skj94r	92	23	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	92	24	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	92	25	pneumonia	pneumonia	NN
cord-291400-o9skj94r	92	26	.	.	.
cord-291400-o9skj94r	93	1	Of	of	IN
cord-291400-o9skj94r	93	2	409	409	CD
cord-291400-o9skj94r	93	3	patients	patient	NNS
cord-291400-o9skj94r	93	4	analyzed	analyze	VBN
cord-291400-o9skj94r	93	5	,	,	,
cord-291400-o9skj94r	93	6	238	238	CD
cord-291400-o9skj94r	93	7	(	(	-LRB-
cord-291400-o9skj94r	93	8	58	58	CD
cord-291400-o9skj94r	93	9	%	%	NN
cord-291400-o9skj94r	93	10	)	)	-RRB-
cord-291400-o9skj94r	93	11	received	receive	VBD
cord-291400-o9skj94r	93	12	empiric	empiric	JJ
cord-291400-o9skj94r	93	13	therapy	therapy	NN
cord-291400-o9skj94r	93	14	with	with	IN
cord-291400-o9skj94r	93	15	a	a	DT
cord-291400-o9skj94r	93	16	b	b	NN
cord-291400-o9skj94r	93	17	-	-	HYPH
cord-291400-o9skj94r	93	18	lactam	lactam	NN
cord-291400-o9skj94r	93	19	plus	plus	CC
cord-291400-o9skj94r	93	20	a	a	DT
cord-291400-o9skj94r	93	21	macrolide	macrolide	NN
cord-291400-o9skj94r	93	22	,	,	,
cord-291400-o9skj94r	93	23	whereas	whereas	IN
cord-291400-o9skj94r	93	24	171	171	CD
cord-291400-o9skj94r	93	25	(	(	-LRB-
cord-291400-o9skj94r	93	26	42	42	CD
cord-291400-o9skj94r	93	27	%	%	NN
cord-291400-o9skj94r	93	28	)	)	-RRB-
cord-291400-o9skj94r	93	29	received	receive	VBD
cord-291400-o9skj94r	93	30	empiric	empiric	JJ
cord-291400-o9skj94r	93	31	therapy	therapy	NN
cord-291400-o9skj94r	93	32	with	with	IN
cord-291400-o9skj94r	93	33	a	a	DT
cord-291400-o9skj94r	93	34	b	b	NN
cord-291400-o9skj94r	93	35	-	-	HYPH
cord-291400-o9skj94r	93	36	lactam	lactam	NN
cord-291400-o9skj94r	93	37	alone	alone	RB
cord-291400-o9skj94r	93	38	.	.	.
cord-291400-o9skj94r	94	1	Potential	potential	JJ
cord-291400-o9skj94r	94	2	risk	risk	NN
cord-291400-o9skj94r	94	3	factors	factor	NNS
cord-291400-o9skj94r	94	4	for	for	IN
cord-291400-o9skj94r	94	5	in	in	IN
cord-291400-o9skj94r	94	6	-	-	HYPH
cord-291400-o9skj94r	94	7	hospital	hospital	NN
cord-291400-o9skj94r	94	8	death	death	NN
cord-291400-o9skj94r	94	9	were	be	VBD
cord-291400-o9skj94r	94	10	identified	identify	VBN
cord-291400-o9skj94r	94	11	in	in	IN
cord-291400-o9skj94r	94	12	stepwise	stepwise	JJ
cord-291400-o9skj94r	94	13	logistic	logistic	JJ
cord-291400-o9skj94r	94	14	regression	regression	NN
cord-291400-o9skj94r	94	15	analysis	analysis	NN
cord-291400-o9skj94r	94	16	.	.	.
cord-291400-o9skj94r	95	1	Multivariate	multivariate	JJ
cord-291400-o9skj94r	95	2	analysis	analysis	NN
cord-291400-o9skj94r	95	3	revealed	reveal	VBD
cord-291400-o9skj94r	95	4	that	that	IN
cord-291400-o9skj94r	95	5	absence	absence	NN
cord-291400-o9skj94r	95	6	of	of	IN
cord-291400-o9skj94r	95	7	a	a	DT
cord-291400-o9skj94r	95	8	macrolide	macrolide	NN
cord-291400-o9skj94r	95	9	in	in	IN
cord-291400-o9skj94r	95	10	the	the	DT
cord-291400-o9skj94r	95	11	initial	initial	JJ
cord-291400-o9skj94r	95	12	empiric	empiric	JJ
cord-291400-o9skj94r	95	13	regimen	regimen	NN
cord-291400-o9skj94r	95	14	independently	independently	RB
cord-291400-o9skj94r	95	15	was	be	VBD
cord-291400-o9skj94r	95	16	associated	associate	VBN
cord-291400-o9skj94r	95	17	with	with	IN
cord-291400-o9skj94r	95	18	death	death	NN
cord-291400-o9skj94r	95	19	(	(	-LRB-
cord-291400-o9skj94r	95	20	P	p	NN
cord-291400-o9skj94r	95	21	=	=	SYM
cord-291400-o9skj94r	95	22	0.03	0.03	CD
cord-291400-o9skj94r	95	23	)	)	-RRB-
cord-291400-o9skj94r	95	24	.	.	.
cord-291400-o9skj94r	96	1	Other	other	JJ
cord-291400-o9skj94r	96	2	independent	independent	JJ
cord-291400-o9skj94r	96	3	predictors	predictor	NNS
cord-291400-o9skj94r	96	4	of	of	IN
cord-291400-o9skj94r	96	5	death	death	NN
cord-291400-o9skj94r	96	6	included	include	VBD
cord-291400-o9skj94r	96	7	shock	shock	NN
cord-291400-o9skj94r	96	8	,	,	,
cord-291400-o9skj94r	96	9	age	age	NN
cord-291400-o9skj94r	96	10	greater	great	JJR
cord-291400-o9skj94r	96	11	than	than	IN
cord-291400-o9skj94r	96	12	64	64	CD
cord-291400-o9skj94r	96	13	years	year	NNS
cord-291400-o9skj94r	96	14	,	,	,
cord-291400-o9skj94r	96	15	and	and	CC
cord-291400-o9skj94r	96	16	a	a	DT
cord-291400-o9skj94r	96	17	blood	blood	NN
cord-291400-o9skj94r	96	18	culture	culture	NN
cord-291400-o9skj94r	96	19	isolate	isolate	NN
cord-291400-o9skj94r	96	20	of	of	IN
cord-291400-o9skj94r	96	21	an	an	DT
cord-291400-o9skj94r	96	22	S	S	NNP
cord-291400-o9skj94r	96	23	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	96	24	strain	strain	VBP
cord-291400-o9skj94r	96	25	resistant	resistant	JJ
cord-291400-o9skj94r	96	26	to	to	IN
cord-291400-o9skj94r	96	27	penicillin	penicillin	NN
cord-291400-o9skj94r	96	28	and	and	CC
cord-291400-o9skj94r	96	29	erythromycin	erythromycin	NN
cord-291400-o9skj94r	96	30	.	.	.
cord-291400-o9skj94r	97	1	A	a	DT
cord-291400-o9skj94r	97	2	total	total	NN
cord-291400-o9skj94r	97	3	of	of	IN
cord-291400-o9skj94r	97	4	35	35	CD
cord-291400-o9skj94r	97	5	patients	patient	NNS
cord-291400-o9skj94r	97	6	(	(	-LRB-
cord-291400-o9skj94r	97	7	9	9	CD
cord-291400-o9skj94r	97	8	%	%	NN
cord-291400-o9skj94r	97	9	)	)	-RRB-
cord-291400-o9skj94r	97	10	died	die	VBD
cord-291400-o9skj94r	97	11	.	.	.
cord-291400-o9skj94r	98	1	Even	even	RB
cord-291400-o9skj94r	98	2	when	when	WRB
cord-291400-o9skj94r	98	3	the	the	DT
cord-291400-o9skj94r	98	4	data	datum	NNS
cord-291400-o9skj94r	98	5	were	be	VBD
cord-291400-o9skj94r	98	6	reanalyzed	reanalyze	VBN
cord-291400-o9skj94r	98	7	to	to	TO
cord-291400-o9skj94r	98	8	exclude	exclude	VB
cord-291400-o9skj94r	98	9	10	10	CD
cord-291400-o9skj94r	98	10	early	early	JJ
cord-291400-o9skj94r	98	11	deaths	death	NNS
cord-291400-o9skj94r	98	12	(	(	-LRB-
cord-291400-o9skj94r	98	13	occurred	occur	VBN
cord-291400-o9skj94r	98	14	\48	\48	CD
cord-291400-o9skj94r	98	15	hours	hour	NNS
cord-291400-o9skj94r	98	16	after	after	IN
cord-291400-o9skj94r	98	17	presentation	presentation	NN
cord-291400-o9skj94r	98	18	)	)	-RRB-
cord-291400-o9skj94r	98	19	,	,	,
cord-291400-o9skj94r	98	20	the	the	DT
cord-291400-o9skj94r	98	21	absence	absence	NN
cord-291400-o9skj94r	98	22	of	of	IN
cord-291400-o9skj94r	98	23	a	a	DT
cord-291400-o9skj94r	98	24	macrolide	macrolide	NN
cord-291400-o9skj94r	98	25	in	in	IN
cord-291400-o9skj94r	98	26	initial	initial	JJ
cord-291400-o9skj94r	98	27	therapy	therapy	NN
cord-291400-o9skj94r	98	28	was	be	VBD
cord-291400-o9skj94r	98	29	associated	associate	VBN
cord-291400-o9skj94r	98	30	with	with	IN
cord-291400-o9skj94r	98	31	death	death	NN
cord-291400-o9skj94r	98	32	(	(	-LRB-
cord-291400-o9skj94r	98	33	OR	or	CC
cord-291400-o9skj94r	98	34	,	,	,
cord-291400-o9skj94r	98	35	.4	.4	NN
cord-291400-o9skj94r	98	36	;	;	:
cord-291400-o9skj94r	98	37	95%CI	95%ci	CD
cord-291400-o9skj94r	98	38	,	,	,
cord-291400-o9skj94r	98	39	0.09	0.09	CD
cord-291400-o9skj94r	98	40	-	-	SYM
cord-291400-o9skj94r	98	41	0.9	0.9	CD
cord-291400-o9skj94r	98	42	)	)	-RRB-
cord-291400-o9skj94r	98	43	.	.	.
cord-291400-o9skj94r	99	1	In	in	IN
cord-291400-o9skj94r	99	2	this	this	DT
cord-291400-o9skj94r	99	3	study	study	NN
cord-291400-o9skj94r	99	4	,	,	,
cord-291400-o9skj94r	99	5	a	a	DT
cord-291400-o9skj94r	99	6	macrolide	macrolide	NN
cord-291400-o9skj94r	99	7	could	could	MD
cord-291400-o9skj94r	99	8	be	be	VB
cord-291400-o9skj94r	99	9	combined	combine	VBN
cord-291400-o9skj94r	99	10	favorably	favorably	RB
cord-291400-o9skj94r	99	11	with	with	IN
cord-291400-o9skj94r	99	12	a	a	DT
cord-291400-o9skj94r	99	13	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	99	14	or	or	CC
cord-291400-o9skj94r	99	15	a	a	DT
cord-291400-o9skj94r	99	16	b	b	NN
cord-291400-o9skj94r	99	17	-	-	HYPH
cord-291400-o9skj94r	99	18	lactamase	lactamase	NN
cord-291400-o9skj94r	99	19	inhibitor	inhibitor	NN
cord-291400-o9skj94r	99	20	.	.	.
cord-291400-o9skj94r	100	1	A	a	DT
cord-291400-o9skj94r	100	2	previous	previous	JJ
cord-291400-o9skj94r	100	3	study	study	NN
cord-291400-o9skj94r	100	4	of	of	IN
cord-291400-o9skj94r	100	5	patients	patient	NNS
cord-291400-o9skj94r	100	6	with	with	IN
cord-291400-o9skj94r	100	7	CAP	CAP	NNP
cord-291400-o9skj94r	100	8	,	,	,
cord-291400-o9skj94r	100	9	but	but	CC
cord-291400-o9skj94r	100	10	not	not	RB
cord-291400-o9skj94r	100	11	nonbacteremic	nonbacteremic	JJ
cord-291400-o9skj94r	100	12	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	100	13	pneumonia	pneumonia	NN
cord-291400-o9skj94r	100	14	,	,	,
cord-291400-o9skj94r	100	15	found	find	VBD
cord-291400-o9skj94r	100	16	that	that	IN
cord-291400-o9skj94r	100	17	treated	treat	VBN
cord-291400-o9skj94r	100	18	with	with	IN
cord-291400-o9skj94r	100	19	blactamase	blactamase	NN
cord-291400-o9skj94r	100	20	inhibitors	inhibitor	NNS
cord-291400-o9skj94r	100	21	and	and	CC
cord-291400-o9skj94r	100	22	a	a	DT
cord-291400-o9skj94r	100	23	macrolide	macrolide	NN
cord-291400-o9skj94r	100	24	were	be	VBD
cord-291400-o9skj94r	100	25	less	less	RBR
cord-291400-o9skj94r	100	26	effective	effective	JJ
cord-291400-o9skj94r	100	27	than	than	IN
cord-291400-o9skj94r	100	28	treatment	treatment	NN
cord-291400-o9skj94r	100	29	with	with	IN
cord-291400-o9skj94r	100	30	a	a	DT
cord-291400-o9skj94r	100	31	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	100	32	alone	alone	JJ
cord-291400-o9skj94r	100	33	[	[	-LRB-
cord-291400-o9skj94r	100	34	32	32	CD
cord-291400-o9skj94r	100	35	]	]	-RRB-
cord-291400-o9skj94r	100	36	.	.	.
cord-291400-o9skj94r	101	1	As	as	IN
cord-291400-o9skj94r	101	2	with	with	IN
cord-291400-o9skj94r	101	3	most	most	JJS
cord-291400-o9skj94r	101	4	retrospective	retrospective	JJ
cord-291400-o9skj94r	101	5	studies	study	NNS
cord-291400-o9skj94r	101	6	,	,	,
cord-291400-o9skj94r	101	7	there	there	EX
cord-291400-o9skj94r	101	8	were	be	VBD
cord-291400-o9skj94r	101	9	differences	difference	NNS
cord-291400-o9skj94r	101	10	among	among	IN
cord-291400-o9skj94r	101	11	the	the	DT
cord-291400-o9skj94r	101	12	popuations	popuation	NNS
cord-291400-o9skj94r	101	13	.	.	.
cord-291400-o9skj94r	102	1	The	the	DT
cord-291400-o9skj94r	102	2	group	group	NN
cord-291400-o9skj94r	102	3	receiving	receive	VBG
cord-291400-o9skj94r	102	4	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	102	5	alone	alone	RB
cord-291400-o9skj94r	102	6	had	have	VBD
cord-291400-o9skj94r	102	7	higher	high	JJR
cord-291400-o9skj94r	102	8	incidences	incidence	NNS
cord-291400-o9skj94r	102	9	of	of	IN
cord-291400-o9skj94r	102	10	comorbid	comorbid	NN
cord-291400-o9skj94r	102	11	conditions	condition	NNS
cord-291400-o9skj94r	102	12	,	,	,
cord-291400-o9skj94r	102	13	HIV	HIV	NNP
cord-291400-o9skj94r	102	14	infection	infection	NN
cord-291400-o9skj94r	102	15	,	,	,
cord-291400-o9skj94r	102	16	hematologic	hematologic	JJ
cord-291400-o9skj94r	102	17	malignancies	malignancy	NNS
cord-291400-o9skj94r	102	18	,	,	,
cord-291400-o9skj94r	103	1	neutropenia	neutropenia	NN
cord-291400-o9skj94r	103	2	,	,	,
cord-291400-o9skj94r	103	3	nosocomial	nosocomial	JJ
cord-291400-o9skj94r	103	4	bacteremia	bacteremia	NN
cord-291400-o9skj94r	103	5	,	,	,
cord-291400-o9skj94r	103	6	and	and	CC
cord-291400-o9skj94r	103	7	penicillin	penicillin	NN
cord-291400-o9skj94r	103	8	-	-	HYPH
cord-291400-o9skj94r	103	9	resistant	resistant	JJ
cord-291400-o9skj94r	103	10	isolates	isolate	NNS
cord-291400-o9skj94r	103	11	.	.	.
cord-291400-o9skj94r	104	1	In	in	IN
cord-291400-o9skj94r	104	2	the	the	DT
cord-291400-o9skj94r	104	3	group	group	NN
cord-291400-o9skj94r	104	4	receiving	receive	VBG
cord-291400-o9skj94r	104	5	b	b	NN
cord-291400-o9skj94r	104	6	-	-	HYPH
cord-291400-o9skj94r	104	7	lactamase	lactamase	NN
cord-291400-o9skj94r	104	8	inhibitors	inhibitor	NNS
cord-291400-o9skj94r	104	9	and	and	CC
cord-291400-o9skj94r	104	10	a	a	DT
cord-291400-o9skj94r	104	11	macrolide	macrolide	NN
cord-291400-o9skj94r	104	12	,	,	,
cord-291400-o9skj94r	104	13	more	more	JJR
cord-291400-o9skj94r	104	14	patients	patient	NNS
cord-291400-o9skj94r	104	15	experienced	experience	VBD
cord-291400-o9skj94r	104	16	shock	shock	NN
cord-291400-o9skj94r	104	17	and	and	CC
cord-291400-o9skj94r	104	18	resultant	resultant	JJ
cord-291400-o9skj94r	104	19	admission	admission	NN
cord-291400-o9skj94r	104	20	to	to	IN
cord-291400-o9skj94r	104	21	ICU	ICU	NNP
cord-291400-o9skj94r	104	22	.	.	.
cord-291400-o9skj94r	105	1	The	the	DT
cord-291400-o9skj94r	105	2	investigators	investigator	NNS
cord-291400-o9skj94r	105	3	caution	caution	VBP
cord-291400-o9skj94r	105	4	that	that	IN
cord-291400-o9skj94r	105	5	a	a	DT
cord-291400-o9skj94r	105	6	prospective	prospective	NN
cord-291400-o9skj94r	105	7	,	,	,
cord-291400-o9skj94r	105	8	randomized	randomized	JJ
cord-291400-o9skj94r	105	9	trial	trial	NN
cord-291400-o9skj94r	105	10	is	be	VBZ
cord-291400-o9skj94r	105	11	necessary	necessary	JJ
cord-291400-o9skj94r	105	12	to	to	TO
cord-291400-o9skj94r	105	13	definitively	definitively	RB
cord-291400-o9skj94r	105	14	determine	determine	VB
cord-291400-o9skj94r	105	15	the	the	DT
cord-291400-o9skj94r	105	16	effect	effect	NN
cord-291400-o9skj94r	105	17	of	of	IN
cord-291400-o9skj94r	105	18	macrolides	macrolide	NNS
cord-291400-o9skj94r	105	19	.	.	.
cord-291400-o9skj94r	106	1	Bacteremic	Bacteremic	NNP
cord-291400-o9skj94r	106	2	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	106	3	pneumonia	pneumonia	NN
cord-291400-o9skj94r	106	4	remains	remain	VBZ
cord-291400-o9skj94r	106	5	a	a	DT
cord-291400-o9skj94r	106	6	serious	serious	JJ
cord-291400-o9skj94r	106	7	life	life	NN
cord-291400-o9skj94r	106	8	-	-	HYPH
cord-291400-o9skj94r	106	9	threatening	threaten	VBG
cord-291400-o9skj94r	106	10	infection	infection	NN
cord-291400-o9skj94r	106	11	.	.	.
cord-291400-o9skj94r	107	1	The	the	DT
cord-291400-o9skj94r	107	2	incidence	incidence	NN
cord-291400-o9skj94r	107	3	of	of	IN
cord-291400-o9skj94r	107	4	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	107	5	bacteremia	bacteremia	NN
cord-291400-o9skj94r	107	6	seems	seem	VBZ
cord-291400-o9skj94r	107	7	to	to	TO
cord-291400-o9skj94r	107	8	be	be	VB
cord-291400-o9skj94r	107	9	increasing	increase	VBG
cord-291400-o9skj94r	107	10	.	.	.
cord-291400-o9skj94r	108	1	The	the	DT
cord-291400-o9skj94r	108	2	CFR	CFR	NNP
cord-291400-o9skj94r	108	3	with	with	IN
cord-291400-o9skj94r	108	4	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	108	5	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	108	6	pneumonia	pneumonia	NN
cord-291400-o9skj94r	108	7	has	have	VBZ
cord-291400-o9skj94r	108	8	not	not	RB
cord-291400-o9skj94r	108	9	changed	change	VBN
cord-291400-o9skj94r	108	10	much	much	JJ
cord-291400-o9skj94r	108	11	in	in	IN
cord-291400-o9skj94r	108	12	the	the	DT
cord-291400-o9skj94r	108	13	past	past	JJ
cord-291400-o9skj94r	108	14	50	50	CD
cord-291400-o9skj94r	108	15	years	year	NNS
cord-291400-o9skj94r	108	16	.	.	.
cord-291400-o9skj94r	109	1	There	there	EX
cord-291400-o9skj94r	109	2	always	always	RB
cord-291400-o9skj94r	109	3	have	have	VBP
cord-291400-o9skj94r	109	4	been	be	VBN
cord-291400-o9skj94r	109	5	unanswered	unanswered	JJ
cord-291400-o9skj94r	109	6	questions	question	NNS
cord-291400-o9skj94r	109	7	with	with	IN
cord-291400-o9skj94r	109	8	regard	regard	NN
cord-291400-o9skj94r	109	9	to	to	IN
cord-291400-o9skj94r	109	10	severe	severe	JJ
cord-291400-o9skj94r	109	11	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	109	12	disease	disease	NN
cord-291400-o9skj94r	109	13	.	.	.
cord-291400-o9skj94r	110	1	Why	why	WRB
cord-291400-o9skj94r	110	2	does	do	VBZ
cord-291400-o9skj94r	110	3	the	the	DT
cord-291400-o9skj94r	110	4	CFR	CFR	NNP
cord-291400-o9skj94r	110	5	differ	differ	VBP
cord-291400-o9skj94r	110	6	among	among	IN
cord-291400-o9skj94r	110	7	different	different	JJ
cord-291400-o9skj94r	110	8	centers	center	NNS
cord-291400-o9skj94r	110	9	and	and	CC
cord-291400-o9skj94r	110	10	countries	country	NNS
cord-291400-o9skj94r	110	11	[	[	-LRB-
cord-291400-o9skj94r	110	12	40	40	CD
cord-291400-o9skj94r	110	13	,	,	,
cord-291400-o9skj94r	110	14	41	41	CD
cord-291400-o9skj94r	110	15	]	]	-RRB-
cord-291400-o9skj94r	110	16	?	?	.
cord-291400-o9skj94r	111	1	Why	why	WRB
cord-291400-o9skj94r	111	2	do	do	VBP
cord-291400-o9skj94r	111	3	some	some	DT
cord-291400-o9skj94r	111	4	countries	country	NNS
cord-291400-o9skj94r	111	5	have	have	VBP
cord-291400-o9skj94r	111	6	many	many	JJ
cord-291400-o9skj94r	111	7	cases	case	NNS
cord-291400-o9skj94r	111	8	of	of	IN
cord-291400-o9skj94r	111	9	nosocomial	nosocomial	JJ
cord-291400-o9skj94r	111	10	S	S	NNP
cord-291400-o9skj94r	111	11	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	111	12	infections	infection	NNS
cord-291400-o9skj94r	111	13	[	[	-LRB-
cord-291400-o9skj94r	111	14	7	7	CD
cord-291400-o9skj94r	111	15	]	]	-RRB-
cord-291400-o9skj94r	111	16	and	and	CC
cord-291400-o9skj94r	111	17	others	other	NNS
cord-291400-o9skj94r	111	18	(	(	-LRB-
cord-291400-o9skj94r	111	19	eg	eg	UH
cord-291400-o9skj94r	111	20	,	,	,
cord-291400-o9skj94r	111	21	the	the	DT
cord-291400-o9skj94r	111	22	United	United	NNP
cord-291400-o9skj94r	111	23	States	States	NNP
cord-291400-o9skj94r	111	24	)	)	-RRB-
cord-291400-o9skj94r	111	25	have	have	VBP
cord-291400-o9skj94r	111	26	a	a	DT
cord-291400-o9skj94r	111	27	minimal	minimal	JJ
cord-291400-o9skj94r	111	28	number	number	NN
cord-291400-o9skj94r	111	29	of	of	IN
cord-291400-o9skj94r	111	30	such	such	JJ
cord-291400-o9skj94r	111	31	cases	case	NNS
cord-291400-o9skj94r	111	32	[	[	-LRB-
cord-291400-o9skj94r	111	33	27	27	CD
cord-291400-o9skj94r	111	34	]	]	-RRB-
cord-291400-o9skj94r	111	35	?	?	.
cord-291400-o9skj94r	112	1	Reports	report	NNS
cord-291400-o9skj94r	112	2	have	have	VBP
cord-291400-o9skj94r	112	3	suggested	suggest	VBN
cord-291400-o9skj94r	112	4	that	that	IN
cord-291400-o9skj94r	112	5	combination	combination	NN
cord-291400-o9skj94r	112	6	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	112	7	therapy	therapy	NN
cord-291400-o9skj94r	112	8	containing	contain	VBG
cord-291400-o9skj94r	112	9	a	a	DT
cord-291400-o9skj94r	112	10	macrolide	macrolide	NN
cord-291400-o9skj94r	112	11	is	be	VBZ
cord-291400-o9skj94r	112	12	more	more	RBR
cord-291400-o9skj94r	112	13	effective	effective	JJ
cord-291400-o9skj94r	112	14	than	than	IN
cord-291400-o9skj94r	112	15	therapy	therapy	NN
cord-291400-o9skj94r	112	16	with	with	IN
cord-291400-o9skj94r	112	17	a	a	DT
cord-291400-o9skj94r	112	18	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	112	19	or	or	CC
cord-291400-o9skj94r	112	20	b	b	NN
cord-291400-o9skj94r	112	21	-	-	:
cord-291400-o9skj94r	112	22	lactam	lactam	NN
cord-291400-o9skj94r	112	23	alone	alone	RB
cord-291400-o9skj94r	113	1	[	[	-LRB-
cord-291400-o9skj94r	113	2	5	5	CD
cord-291400-o9skj94r	113	3	]	]	-RRB-
cord-291400-o9skj94r	113	4	[	[	-LRB-
cord-291400-o9skj94r	113	5	6	6	CD
cord-291400-o9skj94r	113	6	]	]	-RRB-
cord-291400-o9skj94r	113	7	[	[	-LRB-
cord-291400-o9skj94r	113	8	7	7	CD
cord-291400-o9skj94r	113	9	]	]	-RRB-
cord-291400-o9skj94r	113	10	.	.	.
cord-291400-o9skj94r	114	1	This	this	DT
cord-291400-o9skj94r	114	2	article	article	NN
cord-291400-o9skj94r	114	3	addresses	address	VBZ
cord-291400-o9skj94r	114	4	the	the	DT
cord-291400-o9skj94r	114	5	published	publish	VBN
cord-291400-o9skj94r	114	6	literature	literature	NN
cord-291400-o9skj94r	114	7	.	.	.
cord-291400-o9skj94r	115	1	Why	why	WRB
cord-291400-o9skj94r	115	2	would	would	MD
cord-291400-o9skj94r	115	3	a	a	DT
cord-291400-o9skj94r	115	4	b	b	NN
cord-291400-o9skj94r	115	5	-	-	:
cord-291400-o9skj94r	115	6	lactam	lactam	NNP
cord-291400-o9skj94r	115	7	(	(	-LRB-
cord-291400-o9skj94r	115	8	cephalosporin	cephalosporin	NNP
cord-291400-o9skj94r	115	9	)	)	-RRB-
cord-291400-o9skj94r	115	10	in	in	IN
cord-291400-o9skj94r	115	11	combination	combination	NN
cord-291400-o9skj94r	115	12	with	with	IN
cord-291400-o9skj94r	115	13	a	a	DT
cord-291400-o9skj94r	115	14	macrolide	macrolide	NN
cord-291400-o9skj94r	115	15	be	be	VB
cord-291400-o9skj94r	115	16	more	more	RBR
cord-291400-o9skj94r	115	17	efficacious	efficacious	JJ
cord-291400-o9skj94r	115	18	than	than	IN
cord-291400-o9skj94r	115	19	a	a	DT
cord-291400-o9skj94r	115	20	b	b	NN
cord-291400-o9skj94r	115	21	-	-	HYPH
cord-291400-o9skj94r	115	22	lactam	lactam	NNP
cord-291400-o9skj94r	115	23	(	(	-LRB-
cord-291400-o9skj94r	115	24	cephalosporin	cephalosporin	NNP
cord-291400-o9skj94r	115	25	)	)	-RRB-
cord-291400-o9skj94r	115	26	alone	alone	RB
cord-291400-o9skj94r	115	27	in	in	IN
cord-291400-o9skj94r	115	28	the	the	DT
cord-291400-o9skj94r	115	29	treatment	treatment	NN
cord-291400-o9skj94r	115	30	of	of	IN
cord-291400-o9skj94r	115	31	patients	patient	NNS
cord-291400-o9skj94r	115	32	with	with	IN
cord-291400-o9skj94r	115	33	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	115	34	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	115	35	pneumonia	pneumonia	NN
cord-291400-o9skj94r	115	36	?	?	.
cord-291400-o9skj94r	116	1	Are	be	VBP
cord-291400-o9skj94r	116	2	there	there	EX
cord-291400-o9skj94r	116	3	interactions	interaction	NNS
cord-291400-o9skj94r	116	4	between	between	IN
cord-291400-o9skj94r	116	5	the	the	DT
cord-291400-o9skj94r	116	6	two	two	CD
cord-291400-o9skj94r	116	7	antibiotics	antibiotic	NNS
cord-291400-o9skj94r	116	8	against	against	IN
cord-291400-o9skj94r	116	9	Streptococcus	streptococcus	NN
cord-291400-o9skj94r	116	10	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	116	11	?	?	.
cord-291400-o9skj94r	117	1	Although	although	IN
cord-291400-o9skj94r	117	2	some	some	DT
cord-291400-o9skj94r	117	3	antibiotic	antibiotic	JJ
cord-291400-o9skj94r	117	4	combinations	combination	NNS
cord-291400-o9skj94r	117	5	have	have	VBP
cord-291400-o9skj94r	117	6	been	be	VBN
cord-291400-o9skj94r	117	7	shown	show	VBN
cord-291400-o9skj94r	117	8	to	to	TO
cord-291400-o9skj94r	117	9	be	be	VB
cord-291400-o9skj94r	117	10	synergistic	synergistic	JJ
cord-291400-o9skj94r	117	11	in	in	IN
cord-291400-o9skj94r	117	12	vitro	vitro	FW
cord-291400-o9skj94r	117	13	and	and	CC
cord-291400-o9skj94r	117	14	in	in	IN
cord-291400-o9skj94r	117	15	vivo	vivo	NNP
cord-291400-o9skj94r	117	16	(	(	-LRB-
cord-291400-o9skj94r	117	17	ie	ie	FW
cord-291400-o9skj94r	117	18	,	,	,
cord-291400-o9skj94r	117	19	ampicillin	ampicillin	NN
cord-291400-o9skj94r	117	20	and	and	CC
cord-291400-o9skj94r	117	21	gentamicin	gentamicin	NNS
cord-291400-o9skj94r	117	22	against	against	IN
cord-291400-o9skj94r	117	23	enterococci	enterococci	NNP
cord-291400-o9skj94r	117	24	)	)	-RRB-
cord-291400-o9skj94r	117	25	,	,	,
cord-291400-o9skj94r	117	26	no	no	DT
cord-291400-o9skj94r	117	27	data	datum	NNS
cord-291400-o9skj94r	117	28	suggest	suggest	VBP
cord-291400-o9skj94r	117	29	that	that	IN
cord-291400-o9skj94r	117	30	such	such	PDT
cord-291400-o9skj94r	117	31	a	a	DT
cord-291400-o9skj94r	117	32	synergistic	synergistic	JJ
cord-291400-o9skj94r	117	33	activity	activity	NN
cord-291400-o9skj94r	117	34	exists	exist	VBZ
cord-291400-o9skj94r	117	35	between	between	IN
cord-291400-o9skj94r	117	36	a	a	DT
cord-291400-o9skj94r	117	37	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	117	38	or	or	CC
cord-291400-o9skj94r	117	39	penicillins	penicillin	NNS
cord-291400-o9skj94r	117	40	and	and	CC
cord-291400-o9skj94r	117	41	a	a	DT
cord-291400-o9skj94r	117	42	macrolide	macrolide	NN
cord-291400-o9skj94r	117	43	against	against	IN
cord-291400-o9skj94r	117	44	pneumococci	pneumococci	NNP
cord-291400-o9skj94r	117	45	[	[	-LRB-
cord-291400-o9skj94r	117	46	42	42	CD
cord-291400-o9skj94r	117	47	]	]	-RRB-
cord-291400-o9skj94r	117	48	.	.	.
cord-291400-o9skj94r	118	1	There	there	EX
cord-291400-o9skj94r	118	2	is	be	VBZ
cord-291400-o9skj94r	118	3	evidence	evidence	NN
cord-291400-o9skj94r	118	4	that	that	IN
cord-291400-o9skj94r	118	5	the	the	DT
cord-291400-o9skj94r	118	6	combination	combination	NN
cord-291400-o9skj94r	118	7	of	of	IN
cord-291400-o9skj94r	118	8	penicillin	penicillin	NN
cord-291400-o9skj94r	118	9	and	and	CC
cord-291400-o9skj94r	118	10	tetracycline	tetracycline	NNP
cord-291400-o9skj94r	118	11	have	have	VBP
cord-291400-o9skj94r	118	12	antagonistic	antagonistic	JJ
cord-291400-o9skj94r	118	13	effects	effect	NNS
cord-291400-o9skj94r	118	14	in	in	IN
cord-291400-o9skj94r	118	15	patients	patient	NNS
cord-291400-o9skj94r	118	16	with	with	IN
cord-291400-o9skj94r	118	17	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	118	18	meningitis	meningitis	NN
cord-291400-o9skj94r	118	19	[	[	-LRB-
cord-291400-o9skj94r	118	20	43	43	CD
cord-291400-o9skj94r	118	21	]	]	-RRB-
cord-291400-o9skj94r	118	22	.	.	.
cord-291400-o9skj94r	119	1	One	one	CD
cord-291400-o9skj94r	119	2	possible	possible	JJ
cord-291400-o9skj94r	119	3	explanation	explanation	NN
cord-291400-o9skj94r	119	4	for	for	IN
cord-291400-o9skj94r	119	5	the	the	DT
cord-291400-o9skj94r	119	6	decreased	decreased	JJ
cord-291400-o9skj94r	119	7	mortality	mortality	NN
cord-291400-o9skj94r	119	8	rate	rate	NN
cord-291400-o9skj94r	119	9	with	with	IN
cord-291400-o9skj94r	119	10	combination	combination	NN
cord-291400-o9skj94r	119	11	therapy	therapy	NN
cord-291400-o9skj94r	119	12	could	could	MD
cord-291400-o9skj94r	119	13	be	be	VB
cord-291400-o9skj94r	119	14	that	that	IN
cord-291400-o9skj94r	119	15	the	the	DT
cord-291400-o9skj94r	119	16	macrolide	macrolide	NN
cord-291400-o9skj94r	119	17	is	be	VBZ
cord-291400-o9skj94r	119	18	somewhat	somewhat	RB
cord-291400-o9skj94r	119	19	antagonistic	antagonistic	JJ
cord-291400-o9skj94r	119	20	against	against	IN
cord-291400-o9skj94r	119	21	the	the	DT
cord-291400-o9skj94r	119	22	rapid	rapid	JJ
cord-291400-o9skj94r	119	23	killing	killing	NN
cord-291400-o9skj94r	119	24	of	of	IN
cord-291400-o9skj94r	119	25	the	the	DT
cord-291400-o9skj94r	119	26	pneumococci	pneumococcus	NNS
cord-291400-o9skj94r	119	27	by	by	IN
cord-291400-o9skj94r	119	28	the	the	DT
cord-291400-o9skj94r	119	29	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	119	30	.	.	.
cord-291400-o9skj94r	120	1	This	this	DT
cord-291400-o9skj94r	120	2	effect	effect	NN
cord-291400-o9skj94r	120	3	could	could	MD
cord-291400-o9skj94r	120	4	slow	slow	VB
cord-291400-o9skj94r	120	5	the	the	DT
cord-291400-o9skj94r	120	6	rapid	rapid	JJ
cord-291400-o9skj94r	120	7	lysis	lysis	NN
cord-291400-o9skj94r	120	8	of	of	IN
cord-291400-o9skj94r	120	9	pneumococci	pneumococcus	NNS
cord-291400-o9skj94r	120	10	and	and	CC
cord-291400-o9skj94r	120	11	abate	abate	VB
cord-291400-o9skj94r	120	12	the	the	DT
cord-291400-o9skj94r	120	13	resultant	resultant	JJ
cord-291400-o9skj94r	120	14	intense	intense	JJ
cord-291400-o9skj94r	120	15	inflammatory	inflammatory	JJ
cord-291400-o9skj94r	120	16	response	response	NN
cord-291400-o9skj94r	120	17	.	.	.
cord-291400-o9skj94r	121	1	Would	Would	MD
cord-291400-o9skj94r	121	2	the	the	DT
cord-291400-o9skj94r	121	3	use	use	NN
cord-291400-o9skj94r	121	4	of	of	IN
cord-291400-o9skj94r	121	5	two	two	CD
cord-291400-o9skj94r	121	6	empiric	empiric	JJ
cord-291400-o9skj94r	121	7	antibiotics	antibiotic	NNS
cord-291400-o9skj94r	121	8	make	make	VBP
cord-291400-o9skj94r	121	9	it	-PRON-	PRP
cord-291400-o9skj94r	121	10	more	more	RBR
cord-291400-o9skj94r	121	11	likely	likely	JJ
cord-291400-o9skj94r	121	12	that	that	IN
cord-291400-o9skj94r	121	13	at	at	RB
cord-291400-o9skj94r	121	14	least	least	RBS
cord-291400-o9skj94r	121	15	one	one	PRP
cord-291400-o9skj94r	121	16	would	would	MD
cord-291400-o9skj94r	121	17	be	be	VB
cord-291400-o9skj94r	121	18	active	active	JJ
cord-291400-o9skj94r	121	19	against	against	IN
cord-291400-o9skj94r	121	20	the	the	DT
cord-291400-o9skj94r	121	21	pneumococcus	pneumococcus	NN
cord-291400-o9skj94r	121	22	?	?	.
cord-291400-o9skj94r	122	1	In	in	IN
cord-291400-o9skj94r	122	2	their	-PRON-	PRP$
cord-291400-o9skj94r	122	3	study	study	NN
cord-291400-o9skj94r	122	4	,	,	,
cord-291400-o9skj94r	122	5	Waterer	Waterer	NNP
cord-291400-o9skj94r	122	6	et	et	NNP
cord-291400-o9skj94r	122	7	al	al	NNP
cord-291400-o9skj94r	122	8	[	[	-LRB-
cord-291400-o9skj94r	122	9	6	6	CD
cord-291400-o9skj94r	122	10	]	]	-RRB-
cord-291400-o9skj94r	122	11	excluded	exclude	VBN
cord-291400-o9skj94r	122	12	organisms	organism	NNS
cord-291400-o9skj94r	122	13	resistant	resistant	JJ
cord-291400-o9skj94r	122	14	to	to	IN
cord-291400-o9skj94r	122	15	empiric	empiric	JJ
cord-291400-o9skj94r	122	16	therapy	therapy	NN
cord-291400-o9skj94r	122	17	and	and	CC
cord-291400-o9skj94r	122	18	still	still	RB
cord-291400-o9skj94r	122	19	demonstrated	demonstrate	VBD
cord-291400-o9skj94r	122	20	a	a	DT
cord-291400-o9skj94r	122	21	benefit	benefit	NN
cord-291400-o9skj94r	122	22	of	of	IN
cord-291400-o9skj94r	122	23	macrolide	macrolide	JJ
cord-291400-o9skj94r	122	24	use	use	NN
cord-291400-o9skj94r	122	25	.	.	.
cord-291400-o9skj94r	123	1	Lujan	Lujan	NNP
cord-291400-o9skj94r	123	2	et	et	NNP
cord-291400-o9skj94r	123	3	al	al	NNP
cord-291400-o9skj94r	123	4	[	[	-LRB-
cord-291400-o9skj94r	123	5	44	44	CD
cord-291400-o9skj94r	123	6	]	]	-RRB-
cord-291400-o9skj94r	123	7	demonstrated	demonstrate	VBD
cord-291400-o9skj94r	123	8	that	that	IN
cord-291400-o9skj94r	123	9	discordant	discordant	JJ
cord-291400-o9skj94r	123	10	therapy	therapy	NN
cord-291400-o9skj94r	123	11	was	be	VBD
cord-291400-o9skj94r	123	12	associated	associate	VBN
cord-291400-o9skj94r	123	13	with	with	IN
cord-291400-o9skj94r	123	14	a	a	DT
cord-291400-o9skj94r	123	15	higher	high	JJR
cord-291400-o9skj94r	123	16	CFR	CFR	NNP
cord-291400-o9skj94r	123	17	.	.	.
cord-291400-o9skj94r	124	1	This	this	DT
cord-291400-o9skj94r	124	2	finding	finding	NN
cord-291400-o9skj94r	124	3	was	be	VBD
cord-291400-o9skj94r	124	4	seen	see	VBN
cord-291400-o9skj94r	124	5	only	only	RB
cord-291400-o9skj94r	124	6	among	among	IN
cord-291400-o9skj94r	124	7	physicians	physician	NNS
cord-291400-o9skj94r	124	8	who	who	WP
cord-291400-o9skj94r	124	9	did	do	VBD
cord-291400-o9skj94r	124	10	not	not	RB
cord-291400-o9skj94r	124	11	use	use	VB
cord-291400-o9skj94r	124	12	third	third	JJ
cord-291400-o9skj94r	124	13	-	-	HYPH
cord-291400-o9skj94r	124	14	generation	generation	NN
cord-291400-o9skj94r	124	15	cephalosporins	cephalosporin	NNS
cord-291400-o9skj94r	124	16	.	.	.
cord-291400-o9skj94r	125	1	Pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	125	2	resistance	resistance	NN
cord-291400-o9skj94r	125	3	to	to	IN
cord-291400-o9skj94r	125	4	ceftriaxone	ceftriaxone	NN
cord-291400-o9skj94r	125	5	or	or	CC
cord-291400-o9skj94r	125	6	cefotaxime	cefotaxime	NN
cord-291400-o9skj94r	125	7	was	be	VBD
cord-291400-o9skj94r	125	8	minimal	minimal	JJ
cord-291400-o9skj94r	125	9	(	(	-LRB-
cord-291400-o9skj94r	125	10	2	2	CD
cord-291400-o9skj94r	125	11	%	%	NN
cord-291400-o9skj94r	125	12	of	of	IN
cord-291400-o9skj94r	125	13	patients	patient	NNS
cord-291400-o9skj94r	125	14	)	)	-RRB-
cord-291400-o9skj94r	125	15	.	.	.
cord-291400-o9skj94r	126	1	What	what	WP
cord-291400-o9skj94r	126	2	is	be	VBZ
cord-291400-o9skj94r	126	3	the	the	DT
cord-291400-o9skj94r	126	4	possibility	possibility	NN
cord-291400-o9skj94r	126	5	that	that	IN
cord-291400-o9skj94r	126	6	the	the	DT
cord-291400-o9skj94r	126	7	macrolide	macrolide	NN
cord-291400-o9skj94r	126	8	is	be	VBZ
cord-291400-o9skj94r	126	9	treating	treat	VBG
cord-291400-o9skj94r	126	10	a	a	DT
cord-291400-o9skj94r	126	11	secondary	secondary	JJ
cord-291400-o9skj94r	126	12	infection	infection	NN
cord-291400-o9skj94r	126	13	in	in	IN
cord-291400-o9skj94r	126	14	a	a	DT
cord-291400-o9skj94r	126	15	patient	patient	NN
cord-291400-o9skj94r	126	16	with	with	IN
cord-291400-o9skj94r	126	17	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	126	18	bacteremia	bacteremia	NN
cord-291400-o9skj94r	126	19	?	?	.
cord-291400-o9skj94r	127	1	Influenza	influenza	NN
cord-291400-o9skj94r	127	2	infection	infection	NN
cord-291400-o9skj94r	127	3	predisposes	predispose	VBZ
cord-291400-o9skj94r	127	4	to	to	IN
cord-291400-o9skj94r	127	5	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	127	6	pneumonia	pneumonia	NN
cord-291400-o9skj94r	127	7	and	and	CC
cord-291400-o9skj94r	127	8	bacteremia	bacteremia	NN
cord-291400-o9skj94r	127	9	through	through	IN
cord-291400-o9skj94r	127	10	several	several	JJ
cord-291400-o9skj94r	127	11	mechanisms	mechanism	NNS
cord-291400-o9skj94r	127	12	.	.	.
cord-291400-o9skj94r	128	1	Co	Co	NNS
cord-291400-o9skj94r	128	2	-	-	NNS
cord-291400-o9skj94r	128	3	infections	infection	NNS
cord-291400-o9skj94r	128	4	with	with	IN
cord-291400-o9skj94r	128	5	atypical	atypical	JJ
cord-291400-o9skj94r	128	6	pathogens	pathogen	NNS
cord-291400-o9skj94r	128	7	that	that	WDT
cord-291400-o9skj94r	128	8	would	would	MD
cord-291400-o9skj94r	128	9	be	be	VB
cord-291400-o9skj94r	128	10	resistant	resistant	JJ
cord-291400-o9skj94r	128	11	to	to	IN
cord-291400-o9skj94r	128	12	a	a	DT
cord-291400-o9skj94r	128	13	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	128	14	but	but	CC
cord-291400-o9skj94r	128	15	susceptible	susceptible	JJ
cord-291400-o9skj94r	128	16	to	to	IN
cord-291400-o9skj94r	128	17	a	a	DT
cord-291400-o9skj94r	128	18	macrolide	macrolide	NN
cord-291400-o9skj94r	128	19	,	,	,
cord-291400-o9skj94r	128	20	including	include	VBG
cord-291400-o9skj94r	128	21	M	M	NNP
cord-291400-o9skj94r	128	22	pneumoniae	pneumoniae	NNS
cord-291400-o9skj94r	128	23	and	and	CC
cord-291400-o9skj94r	128	24	C	C	NNP
cord-291400-o9skj94r	128	25	pneumoniae	pneumoniae	NNS
cord-291400-o9skj94r	128	26	,	,	,
cord-291400-o9skj94r	128	27	have	have	VBP
cord-291400-o9skj94r	128	28	been	be	VBN
cord-291400-o9skj94r	128	29	described	describe	VBN
cord-291400-o9skj94r	128	30	[	[	-LRB-
cord-291400-o9skj94r	128	31	8	8	CD
cord-291400-o9skj94r	128	32	]	]	-RRB-
cord-291400-o9skj94r	129	1	[	[	-LRB-
cord-291400-o9skj94r	129	2	9	9	CD
cord-291400-o9skj94r	129	3	]	]	-RRB-
cord-291400-o9skj94r	129	4	[	[	-LRB-
cord-291400-o9skj94r	129	5	10	10	CD
cord-291400-o9skj94r	129	6	]	]	-RRB-
cord-291400-o9skj94r	129	7	[	[	-LRB-
cord-291400-o9skj94r	129	8	11	11	CD
cord-291400-o9skj94r	129	9	]	]	-RRB-
cord-291400-o9skj94r	130	1	[	[	-LRB-
cord-291400-o9skj94r	130	2	14	14	CD
cord-291400-o9skj94r	130	3	]	]	-RRB-
cord-291400-o9skj94r	130	4	[	[	-LRB-
cord-291400-o9skj94r	130	5	15	15	CD
cord-291400-o9skj94r	130	6	]	]	-RRB-
cord-291400-o9skj94r	130	7	[	[	-LRB-
cord-291400-o9skj94r	130	8	16	16	CD
cord-291400-o9skj94r	130	9	]	]	-RRB-
cord-291400-o9skj94r	130	10	.	.	.
cord-291400-o9skj94r	131	1	It	-PRON-	PRP
cord-291400-o9skj94r	131	2	is	be	VBZ
cord-291400-o9skj94r	131	3	not	not	RB
cord-291400-o9skj94r	131	4	clear	clear	JJ
cord-291400-o9skj94r	131	5	whether	whether	IN
cord-291400-o9skj94r	131	6	patients	patient	NNS
cord-291400-o9skj94r	131	7	with	with	IN
cord-291400-o9skj94r	131	8	dual	dual	JJ
cord-291400-o9skj94r	131	9	infections	infection	NNS
cord-291400-o9skj94r	131	10	fare	fare	VBP
cord-291400-o9skj94r	131	11	worse	worse	RBR
cord-291400-o9skj94r	131	12	if	if	IN
cord-291400-o9skj94r	131	13	only	only	RB
cord-291400-o9skj94r	131	14	the	the	DT
cord-291400-o9skj94r	131	15	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	131	16	bacteremia	bacteremia	NN
cord-291400-o9skj94r	131	17	is	be	VBZ
cord-291400-o9skj94r	131	18	treated	treat	VBN
cord-291400-o9skj94r	131	19	.	.	.
cord-291400-o9skj94r	132	1	Co	co	NN
cord-291400-o9skj94r	132	2	-	-	NN
cord-291400-o9skj94r	132	3	infection	infection	NN
cord-291400-o9skj94r	132	4	with	with	IN
cord-291400-o9skj94r	132	5	S	S	NNP
cord-291400-o9skj94r	132	6	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	132	7	and	and	CC
cord-291400-o9skj94r	132	8	L	L	NNP
cord-291400-o9skj94r	132	9	pneumophila	pneumophila	NN
cord-291400-o9skj94r	132	10	has	have	VBZ
cord-291400-o9skj94r	132	11	been	be	VBN
cord-291400-o9skj94r	132	12	described	describe	VBN
cord-291400-o9skj94r	132	13	[	[	-LRB-
cord-291400-o9skj94r	132	14	26	26	CD
cord-291400-o9skj94r	132	15	]	]	-RRB-
cord-291400-o9skj94r	132	16	.	.	.
cord-291400-o9skj94r	133	1	In	in	IN
cord-291400-o9skj94r	133	2	most	most	JJS
cord-291400-o9skj94r	133	3	epidemiologic	epidemiologic	JJ
cord-291400-o9skj94r	133	4	studies	study	NNS
cord-291400-o9skj94r	133	5	of	of	IN
cord-291400-o9skj94r	133	6	CAP	CAP	NNP
cord-291400-o9skj94r	133	7	,	,	,
cord-291400-o9skj94r	133	8	an	an	DT
cord-291400-o9skj94r	133	9	etiologic	etiologic	JJ
cord-291400-o9skj94r	133	10	agent	agent	NN
cord-291400-o9skj94r	133	11	is	be	VBZ
cord-291400-o9skj94r	133	12	not	not	RB
cord-291400-o9skj94r	133	13	identified	identify	VBN
cord-291400-o9skj94r	133	14	in	in	IN
cord-291400-o9skj94r	133	15	a	a	DT
cord-291400-o9skj94r	133	16	large	large	JJ
cord-291400-o9skj94r	133	17	proportion	proportion	NN
cord-291400-o9skj94r	133	18	of	of	IN
cord-291400-o9skj94r	133	19	patients	patient	NNS
cord-291400-o9skj94r	133	20	(	(	-LRB-
cord-291400-o9skj94r	133	21	25%-50	25%-50	CD
cord-291400-o9skj94r	133	22	%	%	NN
cord-291400-o9skj94r	133	23	)	)	-RRB-
cord-291400-o9skj94r	133	24	[	[	-LRB-
cord-291400-o9skj94r	133	25	12	12	CD
cord-291400-o9skj94r	133	26	,	,	,
cord-291400-o9skj94r	133	27	15	15	CD
cord-291400-o9skj94r	133	28	]	]	-RRB-
cord-291400-o9skj94r	133	29	.	.	.
cord-291400-o9skj94r	134	1	It	-PRON-	PRP
cord-291400-o9skj94r	134	2	is	be	VBZ
cord-291400-o9skj94r	134	3	possible	possible	JJ
cord-291400-o9skj94r	134	4	that	that	IN
cord-291400-o9skj94r	134	5	other	other	JJ
cord-291400-o9skj94r	134	6	pulmonary	pulmonary	JJ
cord-291400-o9skj94r	134	7	pathogens	pathogen	NNS
cord-291400-o9skj94r	134	8	that	that	WDT
cord-291400-o9skj94r	134	9	are	be	VBP
cord-291400-o9skj94r	134	10	susceptible	susceptible	JJ
cord-291400-o9skj94r	134	11	to	to	IN
cord-291400-o9skj94r	134	12	macrolides	macrolide	NNS
cord-291400-o9skj94r	134	13	have	have	VBP
cord-291400-o9skj94r	134	14	not	not	RB
cord-291400-o9skj94r	134	15	been	be	VBN
cord-291400-o9skj94r	134	16	identified	identify	VBN
cord-291400-o9skj94r	134	17	.	.	.
cord-291400-o9skj94r	135	1	McNally	McNally	NNP
cord-291400-o9skj94r	135	2	et	et	NNP
cord-291400-o9skj94r	135	3	al	al	NNP
cord-291400-o9skj94r	135	4	[	[	-LRB-
cord-291400-o9skj94r	135	5	45	45	CD
cord-291400-o9skj94r	135	6	]	]	-RRB-
cord-291400-o9skj94r	135	7	screened	screen	VBD
cord-291400-o9skj94r	135	8	100	100	CD
cord-291400-o9skj94r	135	9	acute	acute	JJ
cord-291400-o9skj94r	135	10	and	and	CC
cord-291400-o9skj94r	135	11	convalescent	convalescent	JJ
cord-291400-o9skj94r	135	12	serum	serum	NN
cord-291400-o9skj94r	135	13	samples	sample	NNS
cord-291400-o9skj94r	135	14	from	from	IN
cord-291400-o9skj94r	135	15	patients	patient	NNS
cord-291400-o9skj94r	135	16	with	with	IN
cord-291400-o9skj94r	135	17	pneumonia	pneumonia	NN
cord-291400-o9skj94r	135	18	of	of	IN
cord-291400-o9skj94r	135	19	unknown	unknown	JJ
cord-291400-o9skj94r	135	20	cause	cause	NN
cord-291400-o9skj94r	135	21	.	.	.
cord-291400-o9skj94r	136	1	Legionella	Legionella	NNP
cord-291400-o9skj94r	136	2	bozemanii	bozemanii	NNP
cord-291400-o9skj94r	136	3	was	be	VBD
cord-291400-o9skj94r	136	4	identified	identify	VBN
cord-291400-o9skj94r	136	5	as	as	IN
cord-291400-o9skj94r	136	6	the	the	DT
cord-291400-o9skj94r	136	7	potential	potential	JJ
cord-291400-o9skj94r	136	8	cause	cause	NN
cord-291400-o9skj94r	136	9	in	in	IN
cord-291400-o9skj94r	136	10	8	8	CD
cord-291400-o9skj94r	136	11	%	%	NN
cord-291400-o9skj94r	136	12	of	of	IN
cord-291400-o9skj94r	136	13	cases	case	NNS
cord-291400-o9skj94r	136	14	using	use	VBG
cord-291400-o9skj94r	136	15	the	the	DT
cord-291400-o9skj94r	136	16	criterion	criterion	NN
cord-291400-o9skj94r	136	17	of	of	IN
cord-291400-o9skj94r	136	18	fourfold	fourfold	JJ
cord-291400-o9skj94r	136	19	rise	rise	NN
cord-291400-o9skj94r	136	20	in	in	IN
cord-291400-o9skj94r	136	21	antibody	antibody	NN
cord-291400-o9skj94r	136	22	titers	titer	NNS
cord-291400-o9skj94r	136	23	between	between	IN
cord-291400-o9skj94r	136	24	acute	acute	JJ
cord-291400-o9skj94r	136	25	and	and	CC
cord-291400-o9skj94r	136	26	convalescent	convalescent	JJ
cord-291400-o9skj94r	136	27	samples	sample	NNS
cord-291400-o9skj94r	136	28	.	.	.
cord-291400-o9skj94r	137	1	It	-PRON-	PRP
cord-291400-o9skj94r	137	2	is	be	VBZ
cord-291400-o9skj94r	137	3	possible	possible	JJ
cord-291400-o9skj94r	137	4	that	that	IN
cord-291400-o9skj94r	137	5	other	other	JJ
cord-291400-o9skj94r	137	6	Legionella	Legionella	NNP
cord-291400-o9skj94r	137	7	[	[	-LRB-
cord-291400-o9skj94r	137	8	46	46	CD
cord-291400-o9skj94r	137	9	]	]	-RRB-
cord-291400-o9skj94r	137	10	or	or	CC
cord-291400-o9skj94r	137	11	Legionella	Legionella	NNP
cord-291400-o9skj94r	137	12	-	-	HYPH
cord-291400-o9skj94r	137	13	like	like	JJ
cord-291400-o9skj94r	137	14	organisms	organism	NNS
cord-291400-o9skj94r	137	15	requiring	require	VBG
cord-291400-o9skj94r	137	16	different	different	JJ
cord-291400-o9skj94r	137	17	growth	growth	NN
cord-291400-o9skj94r	137	18	medium	medium	NN
cord-291400-o9skj94r	137	19	will	will	MD
cord-291400-o9skj94r	137	20	be	be	VB
cord-291400-o9skj94r	137	21	identified	identify	VBN
cord-291400-o9skj94r	137	22	[	[	-LRB-
cord-291400-o9skj94r	137	23	47	47	CD
cord-291400-o9skj94r	137	24	,	,	,
cord-291400-o9skj94r	137	25	48	48	CD
cord-291400-o9skj94r	137	26	]	]	-RRB-
cord-291400-o9skj94r	137	27	.	.	.
cord-291400-o9skj94r	138	1	What	what	WP
cord-291400-o9skj94r	138	2	is	be	VBZ
cord-291400-o9skj94r	138	3	the	the	DT
cord-291400-o9skj94r	138	4	possibility	possibility	NN
cord-291400-o9skj94r	138	5	that	that	IN
cord-291400-o9skj94r	138	6	the	the	DT
cord-291400-o9skj94r	138	7	immune	immune	NN
cord-291400-o9skj94r	138	8	-	-	HYPH
cord-291400-o9skj94r	138	9	modulating	modulate	VBG
cord-291400-o9skj94r	138	10	activity	activity	NN
cord-291400-o9skj94r	138	11	of	of	IN
cord-291400-o9skj94r	138	12	macrolides	macrolide	NNS
cord-291400-o9skj94r	138	13	is	be	VBZ
cord-291400-o9skj94r	138	14	important	important	JJ
cord-291400-o9skj94r	138	15	in	in	IN
cord-291400-o9skj94r	138	16	reducing	reduce	VBG
cord-291400-o9skj94r	138	17	the	the	DT
cord-291400-o9skj94r	138	18	mortality	mortality	NN
cord-291400-o9skj94r	138	19	rate	rate	NN
cord-291400-o9skj94r	138	20	?	?	.
cord-291400-o9skj94r	139	1	The	the	DT
cord-291400-o9skj94r	139	2	intense	intense	JJ
cord-291400-o9skj94r	139	3	host	host	NN
cord-291400-o9skj94r	139	4	inflammatory	inflammatory	JJ
cord-291400-o9skj94r	139	5	response	response	NN
cord-291400-o9skj94r	139	6	with	with	IN
cord-291400-o9skj94r	139	7	sepsis	sepsis	NN
cord-291400-o9skj94r	139	8	sometimes	sometimes	RB
cord-291400-o9skj94r	139	9	is	be	VBZ
cord-291400-o9skj94r	139	10	deleterious	deleterious	JJ
cord-291400-o9skj94r	139	11	.	.	.
cord-291400-o9skj94r	140	1	Multiple	multiple	JJ
cord-291400-o9skj94r	140	2	studies	study	NNS
cord-291400-o9skj94r	140	3	have	have	VBP
cord-291400-o9skj94r	140	4	used	use	VBN
cord-291400-o9skj94r	140	5	different	different	JJ
cord-291400-o9skj94r	140	6	agents	agent	NNS
cord-291400-o9skj94r	140	7	to	to	TO
cord-291400-o9skj94r	140	8	try	try	VB
cord-291400-o9skj94r	140	9	to	to	TO
cord-291400-o9skj94r	140	10	diminish	diminish	VB
cord-291400-o9skj94r	140	11	this	this	DT
cord-291400-o9skj94r	140	12	exaggerated	exaggerated	JJ
cord-291400-o9skj94r	140	13	immune	immune	JJ
cord-291400-o9skj94r	140	14	response	response	NN
cord-291400-o9skj94r	140	15	[	[	-LRB-
cord-291400-o9skj94r	140	16	49	49	CD
cord-291400-o9skj94r	140	17	]	]	-RRB-
cord-291400-o9skj94r	140	18	[	[	-LRB-
cord-291400-o9skj94r	140	19	50	50	CD
cord-291400-o9skj94r	140	20	]	]	-RRB-
cord-291400-o9skj94r	140	21	[	[	-LRB-
cord-291400-o9skj94r	140	22	51	51	CD
cord-291400-o9skj94r	140	23	]	]	-RRB-
cord-291400-o9skj94r	140	24	[	[	-LRB-
cord-291400-o9skj94r	140	25	52	52	CD
cord-291400-o9skj94r	140	26	]	]	-RRB-
cord-291400-o9skj94r	140	27	.	.	.
cord-291400-o9skj94r	141	1	Steroids	steroid	NNS
cord-291400-o9skj94r	141	2	were	be	VBD
cord-291400-o9skj94r	141	3	studied	study	VBN
cord-291400-o9skj94r	141	4	in	in	IN
cord-291400-o9skj94r	141	5	multiple	multiple	JJ
cord-291400-o9skj94r	141	6	doses	dose	NNS
cord-291400-o9skj94r	141	7	in	in	IN
cord-291400-o9skj94r	141	8	many	many	JJ
cord-291400-o9skj94r	141	9	studies	study	NNS
cord-291400-o9skj94r	141	10	,	,	,
cord-291400-o9skj94r	141	11	and	and	CC
cord-291400-o9skj94r	141	12	success	success	NN
cord-291400-o9skj94r	141	13	was	be	VBD
cord-291400-o9skj94r	141	14	difficult	difficult	JJ
cord-291400-o9skj94r	141	15	to	to	TO
cord-291400-o9skj94r	141	16	demonstrate	demonstrate	VB
cord-291400-o9skj94r	141	17	in	in	IN
cord-291400-o9skj94r	141	18	patients	patient	NNS
cord-291400-o9skj94r	141	19	with	with	IN
cord-291400-o9skj94r	141	20	sepsis	sepsis	NN
cord-291400-o9skj94r	141	21	.	.	.
cord-291400-o9skj94r	142	1	If	if	IN
cord-291400-o9skj94r	142	2	given	give	VBN
cord-291400-o9skj94r	142	3	before	before	IN
cord-291400-o9skj94r	142	4	antibiotics	antibiotic	NNS
cord-291400-o9skj94r	142	5	,	,	,
cord-291400-o9skj94r	142	6	however	however	RB
cord-291400-o9skj94r	142	7	,	,	,
cord-291400-o9skj94r	142	8	steroids	steroid	NNS
cord-291400-o9skj94r	142	9	seemed	seem	VBD
cord-291400-o9skj94r	142	10	to	to	TO
cord-291400-o9skj94r	142	11	help	help	VB
cord-291400-o9skj94r	142	12	reduce	reduce	VB
cord-291400-o9skj94r	142	13	the	the	DT
cord-291400-o9skj94r	142	14	morbidity	morbidity	NN
cord-291400-o9skj94r	142	15	rate	rate	NN
cord-291400-o9skj94r	142	16	in	in	IN
cord-291400-o9skj94r	142	17	patients	patient	NNS
cord-291400-o9skj94r	142	18	with	with	IN
cord-291400-o9skj94r	142	19	bacterial	bacterial	JJ
cord-291400-o9skj94r	142	20	meningitis	meningitis	NN
cord-291400-o9skj94r	142	21	[	[	-LRB-
cord-291400-o9skj94r	142	22	53	53	CD
cord-291400-o9skj94r	142	23	,	,	,
cord-291400-o9skj94r	142	24	54	54	CD
cord-291400-o9skj94r	142	25	]	]	-RRB-
cord-291400-o9skj94r	142	26	.	.	.
cord-291400-o9skj94r	143	1	Studies	study	NNS
cord-291400-o9skj94r	143	2	of	of	IN
cord-291400-o9skj94r	143	3	patients	patient	NNS
cord-291400-o9skj94r	143	4	with	with	IN
cord-291400-o9skj94r	143	5	difficult	difficult	JJ
cord-291400-o9skj94r	143	6	sepsis	sepsis	NN
cord-291400-o9skj94r	143	7	in	in	IN
cord-291400-o9skj94r	143	8	various	various	JJ
cord-291400-o9skj94r	143	9	stages	stage	NNS
cord-291400-o9skj94r	143	10	of	of	IN
cord-291400-o9skj94r	143	11	illness	illness	NN
cord-291400-o9skj94r	143	12	who	who	WP
cord-291400-o9skj94r	143	13	were	be	VBD
cord-291400-o9skj94r	143	14	treated	treat	VBN
cord-291400-o9skj94r	143	15	with	with	IN
cord-291400-o9skj94r	143	16	antibodies	antibody	NNS
cord-291400-o9skj94r	143	17	to	to	TO
cord-291400-o9skj94r	143	18	endotoxin	endotoxin	VB
cord-291400-o9skj94r	143	19	and	and	CC
cord-291400-o9skj94r	143	20	tumor	tumor	NN
cord-291400-o9skj94r	143	21	necrosis	necrosis	NN
cord-291400-o9skj94r	143	22	factor	factor	NN
cord-291400-o9skj94r	143	23	(	(	-LRB-
cord-291400-o9skj94r	143	24	TNF	TNF	NNP
cord-291400-o9skj94r	143	25	)	)	-RRB-
cord-291400-o9skj94r	143	26	have	have	VBP
cord-291400-o9skj94r	143	27	had	have	VBN
cord-291400-o9skj94r	143	28	differing	differ	VBG
cord-291400-o9skj94r	143	29	results	result	NNS
cord-291400-o9skj94r	143	30	.	.	.
cord-291400-o9skj94r	144	1	One	one	CD
cord-291400-o9skj94r	144	2	murine	murine	JJ
cord-291400-o9skj94r	144	3	study	study	NN
cord-291400-o9skj94r	144	4	showed	show	VBD
cord-291400-o9skj94r	144	5	that	that	IN
cord-291400-o9skj94r	144	6	antibodies	antibody	NNS
cord-291400-o9skj94r	144	7	to	to	IN
cord-291400-o9skj94r	144	8	TNF	TNF	NNP
cord-291400-o9skj94r	144	9	had	have	VBD
cord-291400-o9skj94r	144	10	a	a	DT
cord-291400-o9skj94r	144	11	deleterious	deleterious	JJ
cord-291400-o9skj94r	144	12	effect	effect	NN
cord-291400-o9skj94r	144	13	in	in	IN
cord-291400-o9skj94r	144	14	mice	mouse	NNS
cord-291400-o9skj94r	144	15	with	with	IN
cord-291400-o9skj94r	144	16	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	144	17	pneumonia	pneumonia	NN
cord-291400-o9skj94r	144	18	that	that	WDT
cord-291400-o9skj94r	144	19	also	also	RB
cord-291400-o9skj94r	144	20	were	be	VBD
cord-291400-o9skj94r	144	21	treated	treat	VBN
cord-291400-o9skj94r	144	22	with	with	IN
cord-291400-o9skj94r	144	23	ceftriaxone	ceftriaxone	NN
cord-291400-o9skj94r	144	24	[	[	-LRB-
cord-291400-o9skj94r	144	25	55	55	CD
cord-291400-o9skj94r	144	26	]	]	-RRB-
cord-291400-o9skj94r	144	27	.	.	.
cord-291400-o9skj94r	145	1	Review	Review	NNP
cord-291400-o9skj94r	145	2	of	of	IN
cord-291400-o9skj94r	145	3	human	human	JJ
cord-291400-o9skj94r	145	4	trials	trial	NNS
cord-291400-o9skj94r	145	5	with	with	IN
cord-291400-o9skj94r	145	6	antibody	antibody	NN
cord-291400-o9skj94r	145	7	to	to	IN
cord-291400-o9skj94r	145	8	TNF	TNF	NNP
cord-291400-o9skj94r	145	9	did	do	VBD
cord-291400-o9skj94r	145	10	not	not	RB
cord-291400-o9skj94r	145	11	show	show	VB
cord-291400-o9skj94r	145	12	any	any	DT
cord-291400-o9skj94r	145	13	effect	effect	NN
cord-291400-o9skj94r	145	14	on	on	IN
cord-291400-o9skj94r	145	15	the	the	DT
cord-291400-o9skj94r	145	16	mortality	mortality	NN
cord-291400-o9skj94r	145	17	rate	rate	NN
cord-291400-o9skj94r	145	18	in	in	IN
cord-291400-o9skj94r	145	19	patients	patient	NNS
cord-291400-o9skj94r	145	20	with	with	IN
cord-291400-o9skj94r	145	21	severe	severe	JJ
cord-291400-o9skj94r	145	22	sepsis	sepsis	NN
cord-291400-o9skj94r	145	23	and	and	CC
cord-291400-o9skj94r	145	24	bacterial	bacterial	JJ
cord-291400-o9skj94r	145	25	pneumonia	pneumonia	NN
cord-291400-o9skj94r	145	26	[	[	-LRB-
cord-291400-o9skj94r	145	27	56	56	CD
cord-291400-o9skj94r	145	28	]	]	-RRB-
cord-291400-o9skj94r	145	29	.	.	.
cord-291400-o9skj94r	146	1	Other	other	JJ
cord-291400-o9skj94r	146	2	components	component	NNS
cord-291400-o9skj94r	146	3	of	of	IN
cord-291400-o9skj94r	146	4	the	the	DT
cord-291400-o9skj94r	146	5	complex	complex	JJ
cord-291400-o9skj94r	146	6	inflammatory	inflammatory	JJ
cord-291400-o9skj94r	146	7	response	response	NN
cord-291400-o9skj94r	146	8	,	,	,
cord-291400-o9skj94r	146	9	such	such	JJ
cord-291400-o9skj94r	146	10	as	as	IN
cord-291400-o9skj94r	146	11	granulocyte	granulocyte	NN
cord-291400-o9skj94r	146	12	colony	colony	NN
cord-291400-o9skj94r	146	13	-	-	HYPH
cord-291400-o9skj94r	146	14	stimulating	stimulate	VBG
cord-291400-o9skj94r	146	15	factor	factor	NN
cord-291400-o9skj94r	146	16	(	(	-LRB-
cord-291400-o9skj94r	146	17	G	G	NNP
cord-291400-o9skj94r	146	18	-	-	HYPH
cord-291400-o9skj94r	146	19	CSF	CSF	NNP
cord-291400-o9skj94r	146	20	)	)	-RRB-
cord-291400-o9skj94r	146	21	,	,	,
cord-291400-o9skj94r	146	22	have	have	VBP
cord-291400-o9skj94r	146	23	been	be	VBN
cord-291400-o9skj94r	146	24	investigated	investigate	VBN
cord-291400-o9skj94r	146	25	in	in	IN
cord-291400-o9skj94r	146	26	mice	mouse	NNS
cord-291400-o9skj94r	146	27	and	and	CC
cord-291400-o9skj94r	146	28	humans	human	NNS
cord-291400-o9skj94r	146	29	.	.	.
cord-291400-o9skj94r	147	1	Local	local	JJ
cord-291400-o9skj94r	147	2	production	production	NN
cord-291400-o9skj94r	147	3	of	of	IN
cord-291400-o9skj94r	147	4	G	G	NNP
cord-291400-o9skj94r	147	5	-	-	HYPH
cord-291400-o9skj94r	147	6	CSF	CSF	NNP
cord-291400-o9skj94r	147	7	seems	seem	VBZ
cord-291400-o9skj94r	147	8	to	to	TO
cord-291400-o9skj94r	147	9	occur	occur	VB
cord-291400-o9skj94r	147	10	at	at	IN
cord-291400-o9skj94r	147	11	the	the	DT
cord-291400-o9skj94r	147	12	site	site	NN
cord-291400-o9skj94r	147	13	of	of	IN
cord-291400-o9skj94r	147	14	infection	infection	NN
cord-291400-o9skj94r	147	15	in	in	IN
cord-291400-o9skj94r	147	16	patients	patient	NNS
cord-291400-o9skj94r	147	17	with	with	IN
cord-291400-o9skj94r	147	18	unilateral	unilateral	JJ
cord-291400-o9skj94r	147	19	pneumonia	pneumonia	NN
cord-291400-o9skj94r	147	20	[	[	-LRB-
cord-291400-o9skj94r	147	21	57	57	CD
cord-291400-o9skj94r	147	22	]	]	-RRB-
cord-291400-o9skj94r	147	23	.	.	.
cord-291400-o9skj94r	148	1	Macrolides	macrolide	NNS
cord-291400-o9skj94r	148	2	have	have	VBP
cord-291400-o9skj94r	148	3	been	be	VBN
cord-291400-o9skj94r	148	4	shown	show	VBN
cord-291400-o9skj94r	148	5	to	to	TO
cord-291400-o9skj94r	148	6	inhibit	inhibit	VB
cord-291400-o9skj94r	148	7	various	various	JJ
cord-291400-o9skj94r	148	8	factors	factor	NNS
cord-291400-o9skj94r	148	9	in	in	IN
cord-291400-o9skj94r	148	10	the	the	DT
cord-291400-o9skj94r	148	11	inflammatory	inflammatory	JJ
cord-291400-o9skj94r	148	12	response	response	NN
cord-291400-o9skj94r	148	13	,	,	,
cord-291400-o9skj94r	148	14	mostly	mostly	RB
cord-291400-o9skj94r	148	15	in	in	IN
cord-291400-o9skj94r	148	16	mice	mouse	NNS
cord-291400-o9skj94r	148	17	.	.	.
cord-291400-o9skj94r	149	1	No	no	DT
cord-291400-o9skj94r	149	2	human	human	JJ
cord-291400-o9skj94r	149	3	studies	study	NNS
cord-291400-o9skj94r	149	4	have	have	VBP
cord-291400-o9skj94r	149	5	shown	show	VBN
cord-291400-o9skj94r	149	6	that	that	IN
cord-291400-o9skj94r	149	7	the	the	DT
cord-291400-o9skj94r	149	8	immune	immune	NN
cord-291400-o9skj94r	149	9	-	-	HYPH
cord-291400-o9skj94r	149	10	modulating	modulate	VBG
cord-291400-o9skj94r	149	11	activity	activity	NN
cord-291400-o9skj94r	149	12	of	of	IN
cord-291400-o9skj94r	149	13	macrolides	macrolide	NNS
cord-291400-o9skj94r	149	14	has	have	VBZ
cord-291400-o9skj94r	149	15	a	a	DT
cord-291400-o9skj94r	149	16	beneficial	beneficial	JJ
cord-291400-o9skj94r	149	17	effect	effect	NN
cord-291400-o9skj94r	149	18	.	.	.
cord-291400-o9skj94r	150	1	Further	further	JJ
cord-291400-o9skj94r	150	2	investigation	investigation	NN
cord-291400-o9skj94r	150	3	into	into	IN
cord-291400-o9skj94r	150	4	the	the	DT
cord-291400-o9skj94r	150	5	complex	complex	JJ
cord-291400-o9skj94r	150	6	immune	immune	JJ
cord-291400-o9skj94r	150	7	response	response	NN
cord-291400-o9skj94r	150	8	and	and	CC
cord-291400-o9skj94r	150	9	its	-PRON-	PRP$
cord-291400-o9skj94r	150	10	saluatory	saluatory	NN
cord-291400-o9skj94r	150	11	or	or	CC
cord-291400-o9skj94r	150	12	deleterious	deleterious	JJ
cord-291400-o9skj94r	150	13	effect	effect	NN
cord-291400-o9skj94r	150	14	on	on	IN
cord-291400-o9skj94r	150	15	the	the	DT
cord-291400-o9skj94r	150	16	mortality	mortality	NN
cord-291400-o9skj94r	150	17	rate	rate	NN
cord-291400-o9skj94r	150	18	is	be	VBZ
cord-291400-o9skj94r	150	19	important	important	JJ
cord-291400-o9skj94r	150	20	.	.	.
cord-291400-o9skj94r	151	1	There	there	EX
cord-291400-o9skj94r	151	2	have	have	VBP
cord-291400-o9skj94r	151	3	been	be	VBN
cord-291400-o9skj94r	151	4	a	a	DT
cord-291400-o9skj94r	151	5	large	large	JJ
cord-291400-o9skj94r	151	6	number	number	NN
cord-291400-o9skj94r	151	7	of	of	IN
cord-291400-o9skj94r	151	8	articles	article	NNS
cord-291400-o9skj94r	151	9	addressing	address	VBG
cord-291400-o9skj94r	151	10	the	the	DT
cord-291400-o9skj94r	151	11	issue	issue	NN
cord-291400-o9skj94r	151	12	of	of	IN
cord-291400-o9skj94r	151	13	in	in	IN
cord-291400-o9skj94r	151	14	vivo	vivo	NNP
cord-291400-o9skj94r	151	15	susceptibility	susceptibility	NN
cord-291400-o9skj94r	151	16	data	datum	NNS
cord-291400-o9skj94r	151	17	with	with	IN
cord-291400-o9skj94r	151	18	erythromycin	erythromycin	JJ
cord-291400-o9skj94r	151	19	and	and	CC
cord-291400-o9skj94r	151	20	other	other	JJ
cord-291400-o9skj94r	151	21	macrolides	macrolide	NNS
cord-291400-o9skj94r	151	22	[	[	-LRB-
cord-291400-o9skj94r	151	23	58	58	CD
cord-291400-o9skj94r	151	24	]	]	-RRB-
cord-291400-o9skj94r	151	25	[	[	-LRB-
cord-291400-o9skj94r	151	26	59	59	CD
cord-291400-o9skj94r	151	27	]	]	-RRB-
cord-291400-o9skj94r	151	28	[	[	-LRB-
cord-291400-o9skj94r	151	29	60	60	CD
cord-291400-o9skj94r	151	30	]	]	-RRB-
cord-291400-o9skj94r	151	31	and	and	CC
cord-291400-o9skj94r	151	32	how	how	WRB
cord-291400-o9skj94r	151	33	it	-PRON-	PRP
cord-291400-o9skj94r	151	34	correlates	correlate	VBZ
cord-291400-o9skj94r	151	35	with	with	IN
cord-291400-o9skj94r	151	36	clinical	clinical	JJ
cord-291400-o9skj94r	151	37	outcome	outcome	NN
cord-291400-o9skj94r	151	38	[	[	-LRB-
cord-291400-o9skj94r	151	39	61	61	CD
cord-291400-o9skj94r	151	40	]	]	-RRB-
cord-291400-o9skj94r	151	41	.	.	.
cord-291400-o9skj94r	152	1	A	a	DT
cord-291400-o9skj94r	152	2	retrospective	retrospective	JJ
cord-291400-o9skj94r	152	3	study	study	NN
cord-291400-o9skj94r	152	4	(	(	-LRB-
cord-291400-o9skj94r	152	5	1997	1997	CD
cord-291400-o9skj94r	152	6	)	)	-RRB-
cord-291400-o9skj94r	152	7	(	(	-LRB-
cord-291400-o9skj94r	152	8	1998	1998	CD
cord-291400-o9skj94r	152	9	)	)	-RRB-
cord-291400-o9skj94r	152	10	(	(	-LRB-
cord-291400-o9skj94r	152	11	1999	1999	CD
cord-291400-o9skj94r	152	12	)	)	-RRB-
cord-291400-o9skj94r	152	13	(	(	-LRB-
cord-291400-o9skj94r	152	14	2000	2000	CD
cord-291400-o9skj94r	152	15	)	)	-RRB-
cord-291400-o9skj94r	152	16	from	from	IN
cord-291400-o9skj94r	152	17	Spain	Spain	NNP
cord-291400-o9skj94r	152	18	examined	examine	VBD
cord-291400-o9skj94r	152	19	603	603	CD
cord-291400-o9skj94r	152	20	patients	patient	NNS
cord-291400-o9skj94r	152	21	who	who	WP
cord-291400-o9skj94r	152	22	were	be	VBD
cord-291400-o9skj94r	152	23	admitted	admit	VBN
cord-291400-o9skj94r	152	24	with	with	IN
cord-291400-o9skj94r	152	25	CAP	CAP	NNP
cord-291400-o9skj94r	152	26	and	and	CC
cord-291400-o9skj94r	152	27	treated	treat	VBN
cord-291400-o9skj94r	152	28	with	with	IN
cord-291400-o9skj94r	152	29	combination	combination	NN
cord-291400-o9skj94r	152	30	therapy	therapy	NN
cord-291400-o9skj94r	152	31	[	[	-LRB-
cord-291400-o9skj94r	152	32	62	62	CD
cord-291400-o9skj94r	152	33	]	]	-RRB-
cord-291400-o9skj94r	152	34	.	.	.
cord-291400-o9skj94r	153	1	All	all	DT
cord-291400-o9skj94r	153	2	of	of	IN
cord-291400-o9skj94r	153	3	the	the	DT
cord-291400-o9skj94r	153	4	patients	patient	NNS
cord-291400-o9skj94r	153	5	received	receive	VBD
cord-291400-o9skj94r	153	6	ceftriaxone	ceftriaxone	NN
cord-291400-o9skj94r	153	7	.	.	.
cord-291400-o9skj94r	154	1	The	the	DT
cord-291400-o9skj94r	154	2	type	type	NN
cord-291400-o9skj94r	154	3	of	of	IN
cord-291400-o9skj94r	154	4	macrolide	macrolide	JJ
cord-291400-o9skj94r	154	5	therapy	therapy	NN
cord-291400-o9skj94r	154	6	was	be	VBD
cord-291400-o9skj94r	154	7	chosen	choose	VBN
cord-291400-o9skj94r	154	8	by	by	IN
cord-291400-o9skj94r	154	9	the	the	DT
cord-291400-o9skj94r	154	10	attending	attend	VBG
cord-291400-o9skj94r	154	11	physician	physician	NN
cord-291400-o9skj94r	154	12	.	.	.
cord-291400-o9skj94r	155	1	The	the	DT
cord-291400-o9skj94r	155	2	choices	choice	NNS
cord-291400-o9skj94r	155	3	were	be	VBD
cord-291400-o9skj94r	155	4	500	500	CD
cord-291400-o9skj94r	155	5	mg	mg	NNS
cord-291400-o9skj94r	155	6	of	of	IN
cord-291400-o9skj94r	155	7	oral	oral	JJ
cord-291400-o9skj94r	155	8	azithromycin	azithromycin	NNP
cord-291400-o9skj94r	155	9	daily	daily	RB
cord-291400-o9skj94r	155	10	for	for	IN
cord-291400-o9skj94r	155	11	3	3	CD
cord-291400-o9skj94r	155	12	days	day	NNS
cord-291400-o9skj94r	155	13	(	(	-LRB-
cord-291400-o9skj94r	155	14	n	n	NN
cord-291400-o9skj94r	155	15	=	=	SYM
cord-291400-o9skj94r	155	16	383	383	CD
cord-291400-o9skj94r	155	17	)	)	-RRB-
cord-291400-o9skj94r	155	18	or	or	CC
cord-291400-o9skj94r	155	19	500	500	CD
cord-291400-o9skj94r	155	20	mg	mg	NN
cord-291400-o9skj94r	155	21	of	of	IN
cord-291400-o9skj94r	155	22	intravenous	intravenous	JJ
cord-291400-o9skj94r	155	23	clarithromycin	clarithromycin	NNP
cord-291400-o9skj94r	155	24	twice	twice	RB
cord-291400-o9skj94r	155	25	daily	daily	RB
cord-291400-o9skj94r	155	26	with	with	IN
cord-291400-o9skj94r	155	27	a	a	DT
cord-291400-o9skj94r	155	28	switch	switch	NN
cord-291400-o9skj94r	155	29	to	to	IN
cord-291400-o9skj94r	155	30	oral	oral	JJ
cord-291400-o9skj94r	155	31	treatment	treatment	NN
cord-291400-o9skj94r	155	32	(	(	-LRB-
cord-291400-o9skj94r	155	33	total	total	JJ
cord-291400-o9skj94r	155	34	duration	duration	NN
cord-291400-o9skj94r	155	35	of	of	IN
cord-291400-o9skj94r	155	36	treatment	treatment	NN
cord-291400-o9skj94r	155	37	,	,	,
cord-291400-o9skj94r	155	38	10	10	CD
cord-291400-o9skj94r	155	39	days	day	NNS
cord-291400-o9skj94r	155	40	;	;	:
cord-291400-o9skj94r	155	41	n	n	NN
cord-291400-o9skj94r	155	42	=	=	SYM
cord-291400-o9skj94r	155	43	220	220	CD
cord-291400-o9skj94r	155	44	)	)	-RRB-
cord-291400-o9skj94r	155	45	.	.	.
cord-291400-o9skj94r	156	1	The	the	DT
cord-291400-o9skj94r	156	2	patients	patient	NNS
cord-291400-o9skj94r	156	3	had	have	VBD
cord-291400-o9skj94r	156	4	similar	similar	JJ
cord-291400-o9skj94r	156	5	ages	age	NNS
cord-291400-o9skj94r	156	6	,	,	,
cord-291400-o9skj94r	156	7	comorbidities	comorbiditie	NNS
cord-291400-o9skj94r	156	8	,	,	,
cord-291400-o9skj94r	156	9	and	and	CC
cord-291400-o9skj94r	156	10	PSIs	psi	NNS
cord-291400-o9skj94r	156	11	.	.	.
cord-291400-o9skj94r	157	1	The	the	DT
cord-291400-o9skj94r	157	2	length	length	NN
cord-291400-o9skj94r	157	3	of	of	IN
cord-291400-o9skj94r	157	4	stay	stay	NN
cord-291400-o9skj94r	157	5	(	(	-LRB-
cord-291400-o9skj94r	157	6	LOS	LOS	NNP
cord-291400-o9skj94r	157	7	)	)	-RRB-
cord-291400-o9skj94r	157	8	for	for	IN
cord-291400-o9skj94r	157	9	the	the	DT
cord-291400-o9skj94r	157	10	azithromycin	azithromycin	NNP
cord-291400-o9skj94r	157	11	group	group	NN
cord-291400-o9skj94r	157	12	was	be	VBD
cord-291400-o9skj94r	157	13	2	2	CD
cord-291400-o9skj94r	157	14	days	day	NNS
cord-291400-o9skj94r	157	15	shorter	short	JJR
cord-291400-o9skj94r	157	16	(	(	-LRB-
cord-291400-o9skj94r	157	17	P	p	NN
cord-291400-o9skj94r	157	18	\	\	CD
cord-291400-o9skj94r	157	19	0.01	0.01	CD
cord-291400-o9skj94r	157	20	)	)	-RRB-
cord-291400-o9skj94r	157	21	.	.	.
cord-291400-o9skj94r	158	1	The	the	DT
cord-291400-o9skj94r	158	2	CFR	CFR	NNP
cord-291400-o9skj94r	158	3	was	be	VBD
cord-291400-o9skj94r	158	4	3.6	3.6	CD
cord-291400-o9skj94r	158	5	%	%	NN
cord-291400-o9skj94r	158	6	in	in	IN
cord-291400-o9skj94r	158	7	the	the	DT
cord-291400-o9skj94r	158	8	azithromycin	azithromycin	NNP
cord-291400-o9skj94r	158	9	group	group	NN
cord-291400-o9skj94r	158	10	and	and	CC
cord-291400-o9skj94r	158	11	7.2	7.2	CD
cord-291400-o9skj94r	158	12	%	%	NN
cord-291400-o9skj94r	158	13	in	in	IN
cord-291400-o9skj94r	158	14	the	the	DT
cord-291400-o9skj94r	158	15	clarithromycin	clarithromycin	NNP
cord-291400-o9skj94r	158	16	group	group	NN
cord-291400-o9skj94r	158	17	(	(	-LRB-
cord-291400-o9skj94r	158	18	P	p	NN
cord-291400-o9skj94r	158	19	\	\	CD
cord-291400-o9skj94r	158	20	0.05	0.05	CD
cord-291400-o9skj94r	158	21	)	)	-RRB-
cord-291400-o9skj94r	158	22	.	.	.
cord-291400-o9skj94r	159	1	There	there	EX
cord-291400-o9skj94r	159	2	was	be	VBD
cord-291400-o9skj94r	159	3	no	no	DT
cord-291400-o9skj94r	159	4	obvious	obvious	JJ
cord-291400-o9skj94r	159	5	reason	reason	NN
cord-291400-o9skj94r	159	6	for	for	IN
cord-291400-o9skj94r	159	7	the	the	DT
cord-291400-o9skj94r	159	8	differences	difference	NNS
cord-291400-o9skj94r	159	9	in	in	IN
cord-291400-o9skj94r	159	10	the	the	DT
cord-291400-o9skj94r	159	11	two	two	CD
cord-291400-o9skj94r	159	12	treatment	treatment	NN
cord-291400-o9skj94r	159	13	arms	arm	NNS
cord-291400-o9skj94r	159	14	.	.	.
cord-291400-o9skj94r	160	1	The	the	DT
cord-291400-o9skj94r	160	2	investigators	investigator	NNS
cord-291400-o9skj94r	160	3	suggested	suggest	VBD
cord-291400-o9skj94r	160	4	that	that	IN
cord-291400-o9skj94r	160	5	compliance	compliance	NN
cord-291400-o9skj94r	160	6	might	may	MD
cord-291400-o9skj94r	160	7	have	have	VB
cord-291400-o9skj94r	160	8	been	be	VBN
cord-291400-o9skj94r	160	9	an	an	DT
cord-291400-o9skj94r	160	10	issue	issue	NN
cord-291400-o9skj94r	160	11	,	,	,
cord-291400-o9skj94r	160	12	because	because	IN
cord-291400-o9skj94r	160	13	patients	patient	NNS
cord-291400-o9skj94r	160	14	in	in	IN
cord-291400-o9skj94r	160	15	the	the	DT
cord-291400-o9skj94r	160	16	azithromycin	azithromycin	NNP
cord-291400-o9skj94r	160	17	arm	arm	NN
cord-291400-o9skj94r	160	18	received	receive	VBD
cord-291400-o9skj94r	160	19	their	-PRON-	PRP$
cord-291400-o9skj94r	160	20	3-day	3-day	JJ
cord-291400-o9skj94r	160	21	course	course	NN
cord-291400-o9skj94r	160	22	in	in	IN
cord-291400-o9skj94r	160	23	the	the	DT
cord-291400-o9skj94r	160	24	hospital	hospital	NN
cord-291400-o9skj94r	160	25	,	,	,
cord-291400-o9skj94r	160	26	whereas	whereas	IN
cord-291400-o9skj94r	160	27	many	many	JJ
cord-291400-o9skj94r	160	28	patients	patient	NNS
cord-291400-o9skj94r	160	29	in	in	IN
cord-291400-o9skj94r	160	30	the	the	DT
cord-291400-o9skj94r	160	31	clarithromycin	clarithromycin	NNP
cord-291400-o9skj94r	160	32	arm	arm	NN
cord-291400-o9skj94r	160	33	had	have	VBD
cord-291400-o9skj94r	160	34	to	to	TO
cord-291400-o9skj94r	160	35	complete	complete	VB
cord-291400-o9skj94r	160	36	their	-PRON-	PRP$
cord-291400-o9skj94r	160	37	course	course	NN
cord-291400-o9skj94r	160	38	at	at	IN
cord-291400-o9skj94r	160	39	home	home	NN
cord-291400-o9skj94r	160	40	.	.	.
cord-291400-o9skj94r	161	1	Other	other	JJ
cord-291400-o9skj94r	161	2	possibilities	possibility	NNS
cord-291400-o9skj94r	161	3	include	include	VBP
cord-291400-o9skj94r	161	4	differences	difference	NNS
cord-291400-o9skj94r	161	5	in	in	IN
cord-291400-o9skj94r	161	6	the	the	DT
cord-291400-o9skj94r	161	7	anti	anti	JJ
cord-291400-o9skj94r	161	8	-	-	JJ
cord-291400-o9skj94r	161	9	inflammatory	inflammatory	JJ
cord-291400-o9skj94r	161	10	attributes	attribute	NNS
cord-291400-o9skj94r	161	11	of	of	IN
cord-291400-o9skj94r	161	12	the	the	DT
cord-291400-o9skj94r	161	13	two	two	CD
cord-291400-o9skj94r	161	14	drugs	drug	NNS
cord-291400-o9skj94r	161	15	and	and	CC
cord-291400-o9skj94r	161	16	the	the	DT
cord-291400-o9skj94r	161	17	presence	presence	NN
cord-291400-o9skj94r	161	18	of	of	IN
cord-291400-o9skj94r	161	19	an	an	DT
cord-291400-o9skj94r	161	20	unknown	unknown	JJ
cord-291400-o9skj94r	161	21	pathogen	pathogen	NN
cord-291400-o9skj94r	161	22	that	that	WDT
cord-291400-o9skj94r	161	23	is	be	VBZ
cord-291400-o9skj94r	161	24	susceptible	susceptible	JJ
cord-291400-o9skj94r	161	25	to	to	IN
cord-291400-o9skj94r	161	26	azithromycin	azithromycin	NN
cord-291400-o9skj94r	161	27	and	and	CC
cord-291400-o9skj94r	161	28	resistant	resistant	JJ
cord-291400-o9skj94r	161	29	to	to	IN
cord-291400-o9skj94r	161	30	clarithromycin	clarithromycin	NNS
cord-291400-o9skj94r	161	31	.	.	.
cord-291400-o9skj94r	162	1	Because	because	IN
cord-291400-o9skj94r	162	2	this	this	DT
cord-291400-o9skj94r	162	3	analysis	analysis	NN
cord-291400-o9skj94r	162	4	was	be	VBD
cord-291400-o9skj94r	162	5	retrospective	retrospective	JJ
cord-291400-o9skj94r	162	6	analysis	analysis	NN
cord-291400-o9skj94r	162	7	,	,	,
cord-291400-o9skj94r	162	8	there	there	EX
cord-291400-o9skj94r	162	9	may	may	MD
cord-291400-o9skj94r	162	10	have	have	VB
cord-291400-o9skj94r	162	11	been	be	VBN
cord-291400-o9skj94r	162	12	undiscovered	undiscovered	JJ
cord-291400-o9skj94r	162	13	biases	bias	NNS
cord-291400-o9skj94r	162	14	.	.	.
cord-291400-o9skj94r	163	1	What	what	WP
cord-291400-o9skj94r	163	2	is	be	VBZ
cord-291400-o9skj94r	163	3	needed	need	VBN
cord-291400-o9skj94r	163	4	in	in	IN
cord-291400-o9skj94r	163	5	the	the	DT
cord-291400-o9skj94r	163	6	future	future	NN
cord-291400-o9skj94r	163	7	?	?	.
cord-291400-o9skj94r	164	1	The	the	DT
cord-291400-o9skj94r	164	2	retrospective	retrospective	JJ
cord-291400-o9skj94r	164	3	studies	study	NNS
cord-291400-o9skj94r	164	4	discussed	discuss	VBD
cord-291400-o9skj94r	164	5	earlier	early	RBR
cord-291400-o9skj94r	164	6	[	[	-LRB-
cord-291400-o9skj94r	164	7	5	5	CD
cord-291400-o9skj94r	164	8	]	]	-RRB-
cord-291400-o9skj94r	164	9	[	[	-LRB-
cord-291400-o9skj94r	164	10	6	6	CD
cord-291400-o9skj94r	164	11	]	]	-RRB-
cord-291400-o9skj94r	164	12	[	[	-LRB-
cord-291400-o9skj94r	164	13	7	7	CD
cord-291400-o9skj94r	164	14	]	]	-RRB-
cord-291400-o9skj94r	164	15	suggest	suggest	VBP
cord-291400-o9skj94r	164	16	that	that	IN
cord-291400-o9skj94r	164	17	combination	combination	NN
cord-291400-o9skj94r	164	18	therapy	therapy	NN
cord-291400-o9skj94r	164	19	is	be	VBZ
cord-291400-o9skj94r	164	20	better	well	JJR
cord-291400-o9skj94r	164	21	than	than	IN
cord-291400-o9skj94r	164	22	cephalosporin	cephalosporin	NN
cord-291400-o9skj94r	164	23	monotherapy	monotherapy	JJ
cord-291400-o9skj94r	164	24	for	for	IN
cord-291400-o9skj94r	164	25	elderly	elderly	JJ
cord-291400-o9skj94r	164	26	patients	patient	NNS
cord-291400-o9skj94r	164	27	with	with	IN
cord-291400-o9skj94r	164	28	CAP	cap	NN
cord-291400-o9skj94r	164	29	and	and	CC
cord-291400-o9skj94r	164	30	older	old	JJR
cord-291400-o9skj94r	164	31	,	,	,
cord-291400-o9skj94r	164	32	sicker	sick	JJR
cord-291400-o9skj94r	164	33	patients	patient	NNS
cord-291400-o9skj94r	164	34	with	with	IN
cord-291400-o9skj94r	164	35	bacteremia	bacteremia	NN
cord-291400-o9skj94r	164	36	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	164	37	pneumonia	pneumonia	NN
cord-291400-o9skj94r	164	38	.	.	.
cord-291400-o9skj94r	165	1	Caution	caution	NN
cord-291400-o9skj94r	165	2	about	about	IN
cord-291400-o9skj94r	165	3	overinterpreting	overinterprete	VBG
cord-291400-o9skj94r	165	4	retrospective	retrospective	JJ
cord-291400-o9skj94r	165	5	studies	study	NNS
cord-291400-o9skj94r	165	6	has	have	VBZ
cord-291400-o9skj94r	165	7	been	be	VBN
cord-291400-o9skj94r	165	8	published	publish	VBN
cord-291400-o9skj94r	165	9	[	[	-LRB-
cord-291400-o9skj94r	165	10	63	63	CD
cord-291400-o9skj94r	165	11	]	]	-RRB-
cord-291400-o9skj94r	166	1	[	[	-LRB-
cord-291400-o9skj94r	166	2	64	64	CD
cord-291400-o9skj94r	166	3	]	]	-RRB-
cord-291400-o9skj94r	166	4	[	[	-LRB-
cord-291400-o9skj94r	166	5	65	65	CD
cord-291400-o9skj94r	166	6	]	]	-RRB-
cord-291400-o9skj94r	166	7	.	.	.
cord-291400-o9skj94r	167	1	Investigations	investigation	NNS
cord-291400-o9skj94r	167	2	into	into	IN
cord-291400-o9skj94r	167	3	the	the	DT
cord-291400-o9skj94r	167	4	inflammatory	inflammatory	JJ
cord-291400-o9skj94r	167	5	response	response	NN
cord-291400-o9skj94r	167	6	in	in	IN
cord-291400-o9skj94r	167	7	patients	patient	NNS
cord-291400-o9skj94r	167	8	with	with	IN
cord-291400-o9skj94r	167	9	severe	severe	JJ
cord-291400-o9skj94r	167	10	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	167	11	pneumonia	pneumonia	NN
cord-291400-o9skj94r	167	12	should	should	MD
cord-291400-o9skj94r	167	13	incorporate	incorporate	VB
cord-291400-o9skj94r	167	14	recent	recent	JJ
cord-291400-o9skj94r	167	15	advances	advance	NNS
cord-291400-o9skj94r	167	16	in	in	IN
cord-291400-o9skj94r	167	17	murine	murine	JJ
cord-291400-o9skj94r	167	18	studies	study	NNS
cord-291400-o9skj94r	167	19	[	[	-LRB-
cord-291400-o9skj94r	167	20	66	66	CD
cord-291400-o9skj94r	167	21	]	]	-RRB-
cord-291400-o9skj94r	167	22	[	[	-LRB-
cord-291400-o9skj94r	167	23	67	67	CD
cord-291400-o9skj94r	167	24	]	]	-RRB-
cord-291400-o9skj94r	167	25	[	[	-LRB-
cord-291400-o9skj94r	167	26	68	68	CD
cord-291400-o9skj94r	167	27	]	]	-RRB-
cord-291400-o9skj94r	167	28	[	[	-LRB-
cord-291400-o9skj94r	167	29	69	69	CD
cord-291400-o9skj94r	167	30	]	]	-RRB-
cord-291400-o9skj94r	167	31	[	[	-LRB-
cord-291400-o9skj94r	167	32	70	70	CD
cord-291400-o9skj94r	167	33	]	]	-RRB-
cord-291400-o9skj94r	167	34	[	[	-LRB-
cord-291400-o9skj94r	167	35	71	71	CD
cord-291400-o9skj94r	167	36	]	]	-RRB-
cord-291400-o9skj94r	167	37	[	[	-LRB-
cord-291400-o9skj94r	167	38	72	72	CD
cord-291400-o9skj94r	167	39	]	]	-RRB-
cord-291400-o9skj94r	167	40	[	[	-LRB-
cord-291400-o9skj94r	167	41	73	73	CD
cord-291400-o9skj94r	167	42	]	]	-RRB-
cord-291400-o9skj94r	167	43	.	.	.
cord-291400-o9skj94r	168	1	Prospective	prospective	JJ
cord-291400-o9skj94r	168	2	studies	study	NNS
cord-291400-o9skj94r	168	3	aimed	aim	VBN
cord-291400-o9skj94r	168	4	at	at	IN
cord-291400-o9skj94r	168	5	testing	test	VBG
cord-291400-o9skj94r	168	6	the	the	DT
cord-291400-o9skj94r	168	7	available	available	JJ
cord-291400-o9skj94r	168	8	hypotheses	hypothesis	NNS
cord-291400-o9skj94r	168	9	need	need	VBP
cord-291400-o9skj94r	168	10	to	to	TO
cord-291400-o9skj94r	168	11	be	be	VB
cord-291400-o9skj94r	168	12	developed	develop	VBN
cord-291400-o9skj94r	168	13	.	.	.
cord-291400-o9skj94r	169	1	The	the	DT
cord-291400-o9skj94r	169	2	S	S	NNP
cord-291400-o9skj94r	169	3	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	169	4	urinary	urinary	JJ
cord-291400-o9skj94r	169	5	antigen	antigen	NN
cord-291400-o9skj94r	169	6	will	will	MD
cord-291400-o9skj94r	169	7	be	be	VB
cord-291400-o9skj94r	169	8	helpful	helpful	JJ
cord-291400-o9skj94r	169	9	in	in	IN
cord-291400-o9skj94r	169	10	defining	define	VBG
cord-291400-o9skj94r	169	11	the	the	DT
cord-291400-o9skj94r	169	12	subset	subset	NN
cord-291400-o9skj94r	169	13	of	of	IN
cord-291400-o9skj94r	169	14	patients	patient	NNS
cord-291400-o9skj94r	169	15	who	who	WP
cord-291400-o9skj94r	169	16	should	should	MD
cord-291400-o9skj94r	169	17	be	be	VB
cord-291400-o9skj94r	169	18	studied	study	VBN
cord-291400-o9skj94r	169	19	intensively	intensively	RB
cord-291400-o9skj94r	169	20	.	.	.
cord-291400-o9skj94r	170	1	Tests	test	NNS
cord-291400-o9skj94r	170	2	are	be	VBP
cord-291400-o9skj94r	170	3	needed	need	VBN
cord-291400-o9skj94r	170	4	that	that	WDT
cord-291400-o9skj94r	170	5	assess	assess	VBP
cord-291400-o9skj94r	170	6	the	the	DT
cord-291400-o9skj94r	170	7	inflammatory	inflammatory	JJ
cord-291400-o9skj94r	170	8	response	response	NN
cord-291400-o9skj94r	170	9	,	,	,
cord-291400-o9skj94r	170	10	resolution	resolution	NN
cord-291400-o9skj94r	170	11	of	of	IN
cord-291400-o9skj94r	170	12	illness	illness	NN
cord-291400-o9skj94r	170	13	(	(	-LRB-
cord-291400-o9skj94r	170	14	ie	ie	FW
cord-291400-o9skj94r	170	15	,	,	,
cord-291400-o9skj94r	170	16	rapidity	rapidity	NN
cord-291400-o9skj94r	170	17	in	in	IN
cord-291400-o9skj94r	170	18	reduction	reduction	NN
cord-291400-o9skj94r	170	19	of	of	IN
cord-291400-o9skj94r	170	20	the	the	DT
cord-291400-o9skj94r	170	21	magnitude	magnitude	NN
cord-291400-o9skj94r	170	22	of	of	IN
cord-291400-o9skj94r	170	23	bacteremia	bacteremia	NN
cord-291400-o9skj94r	170	24	)	)	-RRB-
cord-291400-o9skj94r	170	25	,	,	,
cord-291400-o9skj94r	170	26	and	and	CC
cord-291400-o9skj94r	170	27	importance	importance	NN
cord-291400-o9skj94r	170	28	of	of	IN
cord-291400-o9skj94r	170	29	alternative	alternative	JJ
cord-291400-o9skj94r	170	30	pathogens	pathogen	NNS
cord-291400-o9skj94r	170	31	(	(	-LRB-
cord-291400-o9skj94r	170	32	M	M	NNP
cord-291400-o9skj94r	170	33	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	170	34	,	,	,
cord-291400-o9skj94r	170	35	C	c	NN
cord-291400-o9skj94r	170	36	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	170	37	,	,	,
cord-291400-o9skj94r	170	38	L	L	NNP
cord-291400-o9skj94r	170	39	pneumophila	pneumophila	NN
cord-291400-o9skj94r	170	40	,	,	,
cord-291400-o9skj94r	170	41	other	other	JJ
cord-291400-o9skj94r	170	42	Legionella	Legionella	NNP
cord-291400-o9skj94r	170	43	spp	spp	NNS
cord-291400-o9skj94r	170	44	and	and	CC
cord-291400-o9skj94r	170	45	viruses	virus	NNS
cord-291400-o9skj94r	170	46	)	)	-RRB-
cord-291400-o9skj94r	170	47	.	.	.
cord-291400-o9skj94r	171	1	Other	other	JJ
cord-291400-o9skj94r	171	2	variables	variable	NNS
cord-291400-o9skj94r	171	3	that	that	WDT
cord-291400-o9skj94r	171	4	should	should	MD
cord-291400-o9skj94r	171	5	be	be	VB
cord-291400-o9skj94r	171	6	taken	take	VBN
cord-291400-o9skj94r	171	7	into	into	IN
cord-291400-o9skj94r	171	8	account	account	NN
cord-291400-o9skj94r	171	9	include	include	VBP
cord-291400-o9skj94r	171	10	the	the	DT
cord-291400-o9skj94r	171	11	specific	specific	JJ
cord-291400-o9skj94r	171	12	macrolide	macrolide	NN
cord-291400-o9skj94r	171	13	used	use	VBN
cord-291400-o9skj94r	171	14	and	and	CC
cord-291400-o9skj94r	171	15	the	the	DT
cord-291400-o9skj94r	171	16	effect	effect	NN
cord-291400-o9skj94r	171	17	of	of	IN
cord-291400-o9skj94r	171	18	other	other	JJ
cord-291400-o9skj94r	171	19	classes	class	NNS
cord-291400-o9skj94r	171	20	of	of	IN
cord-291400-o9skj94r	171	21	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	171	22	agents	agent	NNS
cord-291400-o9skj94r	171	23	,	,	,
cord-291400-o9skj94r	171	24	such	such	JJ
cord-291400-o9skj94r	171	25	as	as	IN
cord-291400-o9skj94r	171	26	fluoroquinolones	fluoroquinolone	NNS
cord-291400-o9skj94r	171	27	.	.	.
cord-291400-o9skj94r	172	1	Ideally	ideally	RB
cord-291400-o9skj94r	172	2	,	,	,
cord-291400-o9skj94r	172	3	the	the	DT
cord-291400-o9skj94r	172	4	study	study	NN
cord-291400-o9skj94r	172	5	would	would	MD
cord-291400-o9skj94r	172	6	include	include	VB
cord-291400-o9skj94r	172	7	provisions	provision	NNS
cord-291400-o9skj94r	172	8	for	for	IN
cord-291400-o9skj94r	172	9	autopsies	autopsy	NNS
cord-291400-o9skj94r	172	10	or	or	CC
cord-291400-o9skj94r	172	11	postmortem	postmortem	JJ
cord-291400-o9skj94r	172	12	pulmonary	pulmonary	JJ
cord-291400-o9skj94r	172	13	biopsies	biopsy	NNS
cord-291400-o9skj94r	172	14	in	in	IN
cord-291400-o9skj94r	172	15	fatal	fatal	JJ
cord-291400-o9skj94r	172	16	cases	case	NNS
cord-291400-o9skj94r	172	17	.	.	.
cord-291400-o9skj94r	173	1	As	as	IN
cord-291400-o9skj94r	173	2	these	these	DT
cord-291400-o9skj94r	173	3	studies	study	NNS
cord-291400-o9skj94r	173	4	are	be	VBP
cord-291400-o9skj94r	173	5	designed	design	VBN
cord-291400-o9skj94r	173	6	and	and	CC
cord-291400-o9skj94r	173	7	performed	perform	VBN
cord-291400-o9skj94r	173	8	,	,	,
cord-291400-o9skj94r	173	9	vigilance	vigilance	NN
cord-291400-o9skj94r	173	10	is	be	VBZ
cord-291400-o9skj94r	173	11	needed	need	VBN
cord-291400-o9skj94r	173	12	in	in	IN
cord-291400-o9skj94r	173	13	the	the	DT
cord-291400-o9skj94r	173	14	immunization	immunization	NN
cord-291400-o9skj94r	173	15	of	of	IN
cord-291400-o9skj94r	173	16	appropriate	appropriate	JJ
cord-291400-o9skj94r	173	17	patients	patient	NNS
cord-291400-o9skj94r	173	18	with	with	IN
cord-291400-o9skj94r	173	19	influenza	influenza	NN
cord-291400-o9skj94r	173	20	and	and	CC
cord-291400-o9skj94r	173	21	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	173	22	vaccines	vaccine	NNS
cord-291400-o9skj94r	173	23	to	to	TO
cord-291400-o9skj94r	173	24	prevent	prevent	VB
cord-291400-o9skj94r	173	25	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	173	26	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	173	27	pneumonia	pneumonia	NN
cord-291400-o9skj94r	173	28	.	.	.
cord-291400-o9skj94r	174	1	Pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	174	2	bacteremia	bacteremia	NN
cord-291400-o9skj94r	174	3	with	with	IN
cord-291400-o9skj94r	174	4	special	special	JJ
cord-291400-o9skj94r	174	5	reference	reference	NN
cord-291400-o9skj94r	174	6	to	to	IN
cord-291400-o9skj94r	174	7	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	174	8	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	174	9	pneumonia	pneumonia	NN
cord-291400-o9skj94r	174	10	Bacteraemic	Bacteraemic	NNP
cord-291400-o9skj94r	174	11	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	174	12	pneumonia	pneumonia	NN
cord-291400-o9skj94r	174	13	:	:	:
cord-291400-o9skj94r	174	14	a	a	DT
cord-291400-o9skj94r	174	15	continuously	continuously	RB
cord-291400-o9skj94r	174	16	evolving	evolve	VBG
cord-291400-o9skj94r	174	17	disease	disease	NN
cord-291400-o9skj94r	174	18	Severe	severe	JJ
cord-291400-o9skj94r	174	19	community	community	NN
cord-291400-o9skj94r	174	20	-	-	HYPH
cord-291400-o9skj94r	174	21	acquired	acquire	VBN
cord-291400-o9skj94r	174	22	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	174	23	pneumonia	pneumonia	NN
cord-291400-o9skj94r	174	24	-	-	:
cord-291400-o9skj94r	174	25	what	what	WP
cord-291400-o9skj94r	174	26	might	may	MD
cord-291400-o9skj94r	174	27	be	be	VB
cord-291400-o9skj94r	174	28	done	do	VBN
cord-291400-o9skj94r	174	29	better	well	JJR
cord-291400-o9skj94r	174	30	Management	Management	NNP
cord-291400-o9skj94r	174	31	of	of	IN
cord-291400-o9skj94r	174	32	community	community	NN
cord-291400-o9skj94r	174	33	-	-	HYPH
cord-291400-o9skj94r	174	34	acquired	acquire	VBN
cord-291400-o9skj94r	174	35	pneumonia	pneumonia	NN
cord-291400-o9skj94r	174	36	in	in	IN
cord-291400-o9skj94r	174	37	the	the	DT
cord-291400-o9skj94r	174	38	era	era	NN
cord-291400-o9skj94r	174	39	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	174	40	resistance	resistance	NN
cord-291400-o9skj94r	174	41	:	:	:
cord-291400-o9skj94r	175	1	a	a	DT
cord-291400-o9skj94r	175	2	report	report	NN
cord-291400-o9skj94r	175	3	from	from	IN
cord-291400-o9skj94r	175	4	the	the	DT
cord-291400-o9skj94r	175	5	drug	drug	NN
cord-291400-o9skj94r	175	6	-	-	HYPH
cord-291400-o9skj94r	175	7	resistant	resistant	JJ
cord-291400-o9skj94r	175	8	Streptococcus	streptococcus	NN
cord-291400-o9skj94r	175	9	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	175	10	therapeutic	therapeutic	JJ
cord-291400-o9skj94r	175	11	working	working	NN
cord-291400-o9skj94r	175	12	group	group	NN
cord-291400-o9skj94r	175	13	Bacteremic	Bacteremic	NNP
cord-291400-o9skj94r	175	14	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	175	15	pneumonia	pneumonia	NN
cord-291400-o9skj94r	175	16	in	in	IN
cord-291400-o9skj94r	175	17	one	one	CD
cord-291400-o9skj94r	175	18	American	American	NNP
cord-291400-o9skj94r	175	19	City	City	NNP
cord-291400-o9skj94r	175	20	:	:	:
cord-291400-o9skj94r	175	21	a	a	DT
cord-291400-o9skj94r	175	22	20-year	20-year	JJ
cord-291400-o9skj94r	175	23	longitudinal	longitudinal	JJ
cord-291400-o9skj94r	175	24	study	study	NN
cord-291400-o9skj94r	175	25	,	,	,
cord-291400-o9skj94r	175	26	1978	1978	CD
cord-291400-o9skj94r	175	27	-	-	SYM
cord-291400-o9skj94r	175	28	1997	1997	CD
cord-291400-o9skj94r	176	1	Monotherapy	Monotherapy	NNP
cord-291400-o9skj94r	176	2	may	may	MD
cord-291400-o9skj94r	176	3	be	be	VB
cord-291400-o9skj94r	176	4	suboptimal	suboptimal	JJ
cord-291400-o9skj94r	176	5	for	for	IN
cord-291400-o9skj94r	176	6	severe	severe	JJ
cord-291400-o9skj94r	176	7	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	176	8	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	176	9	pneumonia	pneumonia	NN
cord-291400-o9skj94r	176	10	Addition	addition	NN
cord-291400-o9skj94r	176	11	of	of	IN
cord-291400-o9skj94r	176	12	a	a	DT
cord-291400-o9skj94r	176	13	macrolide	macrolide	NN
cord-291400-o9skj94r	176	14	to	to	IN
cord-291400-o9skj94r	176	15	a	a	DT
cord-291400-o9skj94r	176	16	beta	beta	NN
cord-291400-o9skj94r	176	17	-	-	HYPH
cord-291400-o9skj94r	176	18	lactam	lactam	NN
cord-291400-o9skj94r	176	19	-	-	HYPH
cord-291400-o9skj94r	176	20	based	base	VBN
cord-291400-o9skj94r	176	21	empirical	empirical	JJ
cord-291400-o9skj94r	176	22	antibiotic	antibiotic	JJ
cord-291400-o9skj94r	176	23	regimen	regimen	NN
cord-291400-o9skj94r	176	24	is	be	VBZ
cord-291400-o9skj94r	176	25	associated	associate	VBN
cord-291400-o9skj94r	176	26	with	with	IN
cord-291400-o9skj94r	176	27	lower	low	JJR
cord-291400-o9skj94r	176	28	in	in	IN
cord-291400-o9skj94r	176	29	-	-	HYPH
cord-291400-o9skj94r	176	30	hospital	hospital	NN
cord-291400-o9skj94r	176	31	mortality	mortality	NN
cord-291400-o9skj94r	176	32	for	for	IN
cord-291400-o9skj94r	176	33	patients	patient	NNS
cord-291400-o9skj94r	176	34	with	with	IN
cord-291400-o9skj94r	176	35	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	176	36	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	176	37	pneumonia	pneumonia	NN
cord-291400-o9skj94r	176	38	Canadian	canadian	JJ
cord-291400-o9skj94r	176	39	guidelines	guideline	NNS
cord-291400-o9skj94r	176	40	for	for	IN
cord-291400-o9skj94r	176	41	the	the	DT
cord-291400-o9skj94r	176	42	initial	initial	JJ
cord-291400-o9skj94r	176	43	management	management	NN
cord-291400-o9skj94r	176	44	of	of	IN
cord-291400-o9skj94r	176	45	community	community	NN
cord-291400-o9skj94r	176	46	-	-	HYPH
cord-291400-o9skj94r	176	47	acquired	acquire	VBN
cord-291400-o9skj94r	176	48	pneumonia	pneumonia	NN
cord-291400-o9skj94r	176	49	-	-	:
cord-291400-o9skj94r	176	50	an	an	DT
cord-291400-o9skj94r	176	51	evidence	evidence	NN
cord-291400-o9skj94r	176	52	-	-	HYPH
cord-291400-o9skj94r	176	53	based	base	VBN
cord-291400-o9skj94r	176	54	update	update	NN
cord-291400-o9skj94r	176	55	by	by	IN
cord-291400-o9skj94r	176	56	the	the	DT
cord-291400-o9skj94r	176	57	Canadian	Canadian	NNP
cord-291400-o9skj94r	176	58	Infectious	Infectious	NNP
cord-291400-o9skj94r	176	59	Disease	Disease	NNP
cord-291400-o9skj94r	176	60	Society	Society	NNP
cord-291400-o9skj94r	176	61	and	and	CC
cord-291400-o9skj94r	176	62	the	the	DT
cord-291400-o9skj94r	176	63	Canadian	canadian	JJ
cord-291400-o9skj94r	176	64	Thoracic	Thoracic	NNP
cord-291400-o9skj94r	176	65	Society	Society	NNP
cord-291400-o9skj94r	176	66	:	:	:
cord-291400-o9skj94r	176	67	the	the	DT
cord-291400-o9skj94r	176	68	Canadian	canadian	JJ
cord-291400-o9skj94r	176	69	CAP	cap	NN
cord-291400-o9skj94r	176	70	working	work	VBG
cord-291400-o9skj94r	176	71	group	group	NN
cord-291400-o9skj94r	176	72	Guidelines	Guidelines	NNPS
cord-291400-o9skj94r	176	73	for	for	IN
cord-291400-o9skj94r	176	74	the	the	DT
cord-291400-o9skj94r	176	75	management	management	NN
cord-291400-o9skj94r	176	76	of	of	IN
cord-291400-o9skj94r	176	77	adults	adult	NNS
cord-291400-o9skj94r	176	78	with	with	IN
cord-291400-o9skj94r	176	79	community	community	NN
cord-291400-o9skj94r	176	80	acquired	acquire	VBD
cord-291400-o9skj94r	176	81	pneumonia	pneumonia	NN
cord-291400-o9skj94r	176	82	:	:	:
cord-291400-o9skj94r	177	1	diagnosis	diagnosis	NN
cord-291400-o9skj94r	177	2	,	,	,
cord-291400-o9skj94r	177	3	assessment	assessment	NN
cord-291400-o9skj94r	177	4	of	of	IN
cord-291400-o9skj94r	177	5	severity	severity	NN
cord-291400-o9skj94r	177	6	,	,	,
cord-291400-o9skj94r	177	7	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	177	8	therapy	therapy	NN
cord-291400-o9skj94r	177	9	,	,	,
cord-291400-o9skj94r	177	10	and	and	CC
cord-291400-o9skj94r	177	11	prevention	prevention	NN
cord-291400-o9skj94r	177	12	Swedish	Swedish	NNP
cord-291400-o9skj94r	177	13	Infectious	Infectious	NNP
cord-291400-o9skj94r	177	14	Diseases	Diseases	NNPS
cord-291400-o9skj94r	178	1	Society	Society	NNP
cord-291400-o9skj94r	178	2	Pneumonia	Pneumonia	NNP
cord-291400-o9skj94r	178	3	Study	Study	NNP
cord-291400-o9skj94r	178	4	Group	Group	NNP
cord-291400-o9skj94r	178	5	:	:	:
cord-291400-o9skj94r	178	6	management	management	NN
cord-291400-o9skj94r	178	7	of	of	IN
cord-291400-o9skj94r	178	8	patients	patient	NNS
cord-291400-o9skj94r	178	9	with	with	IN
cord-291400-o9skj94r	178	10	community	community	NN
cord-291400-o9skj94r	178	11	-	-	HYPH
cord-291400-o9skj94r	178	12	acquired	acquire	VBN
cord-291400-o9skj94r	178	13	pneumonia	pneumonia	NN
cord-291400-o9skj94r	178	14	treated	treat	VBN
cord-291400-o9skj94r	178	15	in	in	IN
cord-291400-o9skj94r	178	16	hospital	hospital	NN
cord-291400-o9skj94r	178	17	in	in	IN
cord-291400-o9skj94r	178	18	Sweden	Sweden	NNP
cord-291400-o9skj94r	178	19	Update	Update	NNP
cord-291400-o9skj94r	178	20	of	of	IN
cord-291400-o9skj94r	178	21	practice	practice	NN
cord-291400-o9skj94r	178	22	guidelines	guideline	NNS
cord-291400-o9skj94r	178	23	for	for	IN
cord-291400-o9skj94r	178	24	the	the	DT
cord-291400-o9skj94r	178	25	management	management	NN
cord-291400-o9skj94r	178	26	of	of	IN
cord-291400-o9skj94r	178	27	community	community	NN
cord-291400-o9skj94r	178	28	-	-	HYPH
cord-291400-o9skj94r	178	29	acquired	acquire	VBN
cord-291400-o9skj94r	178	30	pneumonia	pneumonia	NN
cord-291400-o9skj94r	178	31	in	in	IN
cord-291400-o9skj94r	178	32	immunocompetent	immunocompetent	JJ
cord-291400-o9skj94r	178	33	adults	adult	NNS
cord-291400-o9skj94r	179	1	Community	community	NN
cord-291400-o9skj94r	179	2	-	-	HYPH
cord-291400-o9skj94r	179	3	acquired	acquire	VBN
cord-291400-o9skj94r	179	4	pneumonia	pneumonia	NN
cord-291400-o9skj94r	179	5	requiring	require	VBG
cord-291400-o9skj94r	179	6	hospitalization	hospitalization	NN
cord-291400-o9skj94r	179	7	:	:	:
cord-291400-o9skj94r	179	8	5-year	5-year	CD
cord-291400-o9skj94r	179	9	prospective	prospective	JJ
cord-291400-o9skj94r	179	10	study	study	NN
cord-291400-o9skj94r	179	11	New	New	NNP
cord-291400-o9skj94r	179	12	and	and	CC
cord-291400-o9skj94r	179	13	emerging	emerge	VBG
cord-291400-o9skj94r	179	14	etiologies	etiology	NNS
cord-291400-o9skj94r	179	15	for	for	IN
cord-291400-o9skj94r	179	16	community	community	NN
cord-291400-o9skj94r	179	17	-	-	HYPH
cord-291400-o9skj94r	179	18	acquired	acquire	VBN
cord-291400-o9skj94r	179	19	pneumonia	pneumonia	NN
cord-291400-o9skj94r	179	20	with	with	IN
cord-291400-o9skj94r	179	21	implications	implication	NNS
cord-291400-o9skj94r	179	22	for	for	IN
cord-291400-o9skj94r	179	23	therapy	therapy	NN
cord-291400-o9skj94r	179	24	:	:	:
cord-291400-o9skj94r	179	25	a	a	DT
cord-291400-o9skj94r	179	26	prospective	prospective	JJ
cord-291400-o9skj94r	179	27	multi	multi	JJ
cord-291400-o9skj94r	179	28	-	-	JJ
cord-291400-o9skj94r	179	29	center	center	JJ
cord-291400-o9skj94r	179	30	study	study	NN
cord-291400-o9skj94r	179	31	of	of	IN
cord-291400-o9skj94r	179	32	359	359	CD
cord-291400-o9skj94r	179	33	cases	case	NNS
cord-291400-o9skj94r	179	34	Multiple	multiple	JJ
cord-291400-o9skj94r	179	35	pathogens	pathogen	NNS
cord-291400-o9skj94r	179	36	in	in	IN
cord-291400-o9skj94r	179	37	adult	adult	NN
cord-291400-o9skj94r	179	38	patients	patient	NNS
cord-291400-o9skj94r	179	39	admitted	admit	VBN
cord-291400-o9skj94r	179	40	with	with	IN
cord-291400-o9skj94r	179	41	community	community	NN
cord-291400-o9skj94r	179	42	-	-	HYPH
cord-291400-o9skj94r	179	43	acquired	acquire	VBN
cord-291400-o9skj94r	179	44	pneumonia	pneumonia	NN
cord-291400-o9skj94r	179	45	:	:	:
cord-291400-o9skj94r	179	46	a	a	DT
cord-291400-o9skj94r	179	47	one	one	CD
cord-291400-o9skj94r	179	48	year	year	NN
cord-291400-o9skj94r	179	49	prospective	prospective	JJ
cord-291400-o9skj94r	179	50	study	study	NN
cord-291400-o9skj94r	179	51	of	of	IN
cord-291400-o9skj94r	179	52	346	346	CD
cord-291400-o9skj94r	179	53	consecutive	consecutive	JJ
cord-291400-o9skj94r	179	54	patients	patient	NNS
cord-291400-o9skj94r	179	55	Incidence	incidence	NN
cord-291400-o9skj94r	179	56	of	of	IN
cord-291400-o9skj94r	179	57	community	community	NN
cord-291400-o9skj94r	179	58	-	-	HYPH
cord-291400-o9skj94r	179	59	acquired	acquire	VBN
cord-291400-o9skj94r	179	60	pneumonia	pneumonia	NN
cord-291400-o9skj94r	179	61	requiring	require	VBG
cord-291400-o9skj94r	179	62	hospitalization	hospitalization	NN
cord-291400-o9skj94r	179	63	Microbial	microbial	JJ
cord-291400-o9skj94r	179	64	etiology	etiology	NN
cord-291400-o9skj94r	179	65	of	of	IN
cord-291400-o9skj94r	179	66	community	community	NN
cord-291400-o9skj94r	179	67	-	-	HYPH
cord-291400-o9skj94r	179	68	acquired	acquire	VBN
cord-291400-o9skj94r	179	69	pneumonia	pneumonia	NN
cord-291400-o9skj94r	179	70	in	in	IN
cord-291400-o9skj94r	179	71	the	the	DT
cord-291400-o9skj94r	179	72	adult	adult	NN
cord-291400-o9skj94r	179	73	population	population	NN
cord-291400-o9skj94r	179	74	of	of	IN
cord-291400-o9skj94r	179	75	4	4	CD
cord-291400-o9skj94r	179	76	municipalities	municipality	NNS
cord-291400-o9skj94r	179	77	in	in	IN
cord-291400-o9skj94r	179	78	eastern	eastern	JJ
cord-291400-o9skj94r	179	79	Finland	Finland	NNP
cord-291400-o9skj94r	179	80	Community	Community	NNP
cord-291400-o9skj94r	179	81	-	-	HYPH
cord-291400-o9skj94r	179	82	acquired	acquire	VBN
cord-291400-o9skj94r	179	83	pneumonia	pneumonia	NN
cord-291400-o9skj94r	179	84	in	in	IN
cord-291400-o9skj94r	179	85	Europe	Europe	NNP
cord-291400-o9skj94r	179	86	:	:	:
cord-291400-o9skj94r	179	87	causative	causative	JJ
cord-291400-o9skj94r	179	88	pathogens	pathogen	NNS
cord-291400-o9skj94r	179	89	and	and	CC
cord-291400-o9skj94r	179	90	resistance	resistance	NN
cord-291400-o9skj94r	179	91	patterns	pattern	NNS
cord-291400-o9skj94r	180	1	A	a	DT
cord-291400-o9skj94r	180	2	new	new	JJ
cord-291400-o9skj94r	180	3	Chlamydia	Chlamydia	NNP
cord-291400-o9skj94r	180	4	psittaci	psittaci	NN
cord-291400-o9skj94r	180	5	strain	strain	NN
cord-291400-o9skj94r	180	6	,	,	,
cord-291400-o9skj94r	180	7	TWAR	TWAR	NNP
cord-291400-o9skj94r	180	8	,	,	,
cord-291400-o9skj94r	180	9	isolated	isolate	VBN
cord-291400-o9skj94r	180	10	in	in	IN
cord-291400-o9skj94r	180	11	acute	acute	JJ
cord-291400-o9skj94r	180	12	respiratory	respiratory	JJ
cord-291400-o9skj94r	180	13	tract	tract	NN
cord-291400-o9skj94r	180	14	infections	infection	NNS
cord-291400-o9skj94r	180	15	Respiratory	respiratory	JJ
cord-291400-o9skj94r	180	16	syncytial	syncytial	JJ
cord-291400-o9skj94r	180	17	virus	virus	NN
cord-291400-o9skj94r	180	18	(	(	-LRB-
cord-291400-o9skj94r	180	19	RSV	RSV	NNP
cord-291400-o9skj94r	180	20	)	)	-RRB-
cord-291400-o9skj94r	180	21	may	may	MD
cord-291400-o9skj94r	180	22	be	be	VB
cord-291400-o9skj94r	180	23	an	an	DT
cord-291400-o9skj94r	180	24	important	important	JJ
cord-291400-o9skj94r	180	25	cause	cause	NN
cord-291400-o9skj94r	180	26	of	of	IN
cord-291400-o9skj94r	180	27	community	community	NN
cord-291400-o9skj94r	180	28	-	-	HYPH
cord-291400-o9skj94r	180	29	acquired	acquire	VBN
cord-291400-o9skj94r	180	30	lower	low	JJR
cord-291400-o9skj94r	180	31	respiratory	respiratory	JJ
cord-291400-o9skj94r	180	32	infection	infection	NN
cord-291400-o9skj94r	180	33	among	among	IN
cord-291400-o9skj94r	180	34	hospitalized	hospitalize	VBN
cord-291400-o9skj94r	180	35	adults	adult	NNS
cord-291400-o9skj94r	181	1	The	the	DT
cord-291400-o9skj94r	181	2	role	role	NN
cord-291400-o9skj94r	181	3	of	of	IN
cord-291400-o9skj94r	181	4	atypical	atypical	JJ
cord-291400-o9skj94r	181	5	pathogens	pathogen	NNS
cord-291400-o9skj94r	181	6	:	:	:
cord-291400-o9skj94r	181	7	Mycoplasma	mycoplasma	NN
cord-291400-o9skj94r	181	8	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	181	9	,	,	,
cord-291400-o9skj94r	181	10	Chlamydia	Chlamydia	NNP
cord-291400-o9skj94r	181	11	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	181	12	and	and	CC
cord-291400-o9skj94r	181	13	Legionella	Legionella	NNP
cord-291400-o9skj94r	181	14	pneumonia	pneumonia	NN
cord-291400-o9skj94r	181	15	in	in	IN
cord-291400-o9skj94r	181	16	respiratory	respiratory	JJ
cord-291400-o9skj94r	181	17	infection	infection	NN
cord-291400-o9skj94r	181	18	Clinical	clinical	JJ
cord-291400-o9skj94r	181	19	characteristics	characteristic	NNS
cord-291400-o9skj94r	181	20	of	of	IN
cord-291400-o9skj94r	181	21	C.	C.	NNP
cord-291400-o9skj94r	181	22	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	181	23	infection	infection	NN
cord-291400-o9skj94r	181	24	as	as	IN
cord-291400-o9skj94r	181	25	the	the	DT
cord-291400-o9skj94r	181	26	sole	sole	JJ
cord-291400-o9skj94r	181	27	cause	cause	NN
cord-291400-o9skj94r	181	28	of	of	IN
cord-291400-o9skj94r	181	29	community	community	NN
cord-291400-o9skj94r	181	30	-	-	HYPH
cord-291400-o9skj94r	181	31	acquired	acquire	VBN
cord-291400-o9skj94r	181	32	pneumonia	pneumonia	NN
cord-291400-o9skj94r	181	33	Parainfluenza	Parainfluenza	NNP
cord-291400-o9skj94r	181	34	virus	virus	NN
cord-291400-o9skj94r	181	35	infection	infection	NN
cord-291400-o9skj94r	181	36	among	among	IN
cord-291400-o9skj94r	181	37	adults	adult	NNS
cord-291400-o9skj94r	181	38	hospitalized	hospitalize	VBN
cord-291400-o9skj94r	181	39	for	for	IN
cord-291400-o9skj94r	181	40	lower	low	JJR
cord-291400-o9skj94r	181	41	respiratory	respiratory	JJ
cord-291400-o9skj94r	181	42	tract	tract	NN
cord-291400-o9skj94r	181	43	infection	infection	NN
cord-291400-o9skj94r	181	44	Importance	importance	NN
cord-291400-o9skj94r	181	45	of	of	IN
cord-291400-o9skj94r	181	46	atypical	atypical	JJ
cord-291400-o9skj94r	181	47	pathogens	pathogen	NNS
cord-291400-o9skj94r	181	48	of	of	IN
cord-291400-o9skj94r	181	49	community	community	NN
cord-291400-o9skj94r	181	50	-	-	HYPH
cord-291400-o9skj94r	181	51	acquired	acquire	VBN
cord-291400-o9skj94r	181	52	pneumonia	pneumonia	NN
cord-291400-o9skj94r	181	53	Role	role	NN
cord-291400-o9skj94r	181	54	of	of	IN
cord-291400-o9skj94r	181	55	neuraminidase	neuraminidase	NN
cord-291400-o9skj94r	181	56	in	in	IN
cord-291400-o9skj94r	181	57	lethal	lethal	JJ
cord-291400-o9skj94r	181	58	synergism	synergism	NN
cord-291400-o9skj94r	181	59	between	between	IN
cord-291400-o9skj94r	181	60	influenza	influenza	NN
cord-291400-o9skj94r	181	61	virus	virus	NN
cord-291400-o9skj94r	181	62	and	and	CC
cord-291400-o9skj94r	181	63	Streptococcus	Streptococcus	NNP
cord-291400-o9skj94r	181	64	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	181	65	Moraxella	Moraxella	NNP
cord-291400-o9skj94r	181	66	catarrhalis	catarrhalis	NNP
cord-291400-o9skj94r	181	67	bacteraemia	bacteraemia	NN
cord-291400-o9skj94r	181	68	associated	associate	VBN
cord-291400-o9skj94r	181	69	with	with	IN
cord-291400-o9skj94r	181	70	Mycoplasma	mycoplasma	NN
cord-291400-o9skj94r	181	71	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	181	72	infection	infection	NN
cord-291400-o9skj94r	181	73	and	and	CC
cord-291400-o9skj94r	181	74	pneumonia	pneumonia	NN
cord-291400-o9skj94r	181	75	Legionnaires	legionnaire	NNS
cord-291400-o9skj94r	181	76	disease	disease	NN
cord-291400-o9skj94r	181	77	with	with	IN
cord-291400-o9skj94r	181	78	bacteremic	bacteremic	NNP
cord-291400-o9skj94r	181	79	coinfection	coinfection	NNP
cord-291400-o9skj94r	181	80	CBPIS	CBPIS	NNP
cord-291400-o9skj94r	181	81	study	study	NN
cord-291400-o9skj94r	181	82	group	group	NN
cord-291400-o9skj94r	181	83	:	:	:
cord-291400-o9skj94r	181	84	Bacteremia	Bacteremia	NNP
cord-291400-o9skj94r	181	85	with	with	IN
cord-291400-o9skj94r	181	86	Streptococcus	streptococcus	NN
cord-291400-o9skj94r	181	87	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	181	88	:	:	:
cord-291400-o9skj94r	181	89	implications	implication	NNS
cord-291400-o9skj94r	181	90	for	for	IN
cord-291400-o9skj94r	181	91	therapy	therapy	NN
cord-291400-o9skj94r	181	92	and	and	CC
cord-291400-o9skj94r	181	93	prevention	prevention	NN
cord-291400-o9skj94r	181	94	Adult	adult	NN
cord-291400-o9skj94r	181	95	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	181	96	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	181	97	pneumonia	pneumonia	NN
cord-291400-o9skj94r	181	98	in	in	IN
cord-291400-o9skj94r	181	99	a	a	DT
cord-291400-o9skj94r	181	100	community	community	NN
cord-291400-o9skj94r	181	101	teaching	teaching	NN
cord-291400-o9skj94r	181	102	hospital	hospital	NN
cord-291400-o9skj94r	181	103	,	,	,
cord-291400-o9skj94r	181	104	1992	1992	CD
cord-291400-o9skj94r	181	105	-	-	SYM
cord-291400-o9skj94r	181	106	1996	1996	CD
cord-291400-o9skj94r	181	107	:	:	:
cord-291400-o9skj94r	181	108	a	a	DT
cord-291400-o9skj94r	181	109	detailed	detailed	JJ
cord-291400-o9skj94r	181	110	analysis	analysis	NN
cord-291400-o9skj94r	181	111	of	of	IN
cord-291400-o9skj94r	181	112	108	108	CD
cord-291400-o9skj94r	181	113	cases	case	NNS
cord-291400-o9skj94r	181	114	Cost	cost	NN
cord-291400-o9skj94r	181	115	-	-	HYPH
cord-291400-o9skj94r	181	116	effectiveness	effectiveness	NN
cord-291400-o9skj94r	181	117	of	of	IN
cord-291400-o9skj94r	181	118	vaccination	vaccination	NN
cord-291400-o9skj94r	181	119	against	against	IN
cord-291400-o9skj94r	181	120	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	181	121	bacteremia	bacteremia	NN
cord-291400-o9skj94r	181	122	among	among	IN
cord-291400-o9skj94r	181	123	elderly	elderly	JJ
cord-291400-o9skj94r	181	124	people	people	NNS
cord-291400-o9skj94r	181	125	Prognosis	prognosis	NN
cord-291400-o9skj94r	181	126	and	and	CC
cord-291400-o9skj94r	181	127	outcomes	outcome	NNS
cord-291400-o9skj94r	181	128	of	of	IN
cord-291400-o9skj94r	181	129	patients	patient	NNS
cord-291400-o9skj94r	181	130	with	with	IN
cord-291400-o9skj94r	181	131	communityacquired	communityacquired	JJ
cord-291400-o9skj94r	181	132	pneumonia	pneumonia	NN
cord-291400-o9skj94r	181	133	Quality	Quality	NNP
cord-291400-o9skj94r	181	134	of	of	IN
cord-291400-o9skj94r	181	135	care	care	NN
cord-291400-o9skj94r	181	136	,	,	,
cord-291400-o9skj94r	181	137	process	process	NN
cord-291400-o9skj94r	181	138	and	and	CC
cord-291400-o9skj94r	181	139	outcomes	outcome	NNS
cord-291400-o9skj94r	181	140	in	in	IN
cord-291400-o9skj94r	181	141	elderly	elderly	JJ
cord-291400-o9skj94r	181	142	patients	patient	NNS
cord-291400-o9skj94r	181	143	with	with	IN
cord-291400-o9skj94r	181	144	pneumonia	pneumonia	NNP
cord-291400-o9skj94r	181	145	Association	Association	NNP
cord-291400-o9skj94r	181	146	between	between	IN
cord-291400-o9skj94r	181	147	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	181	148	therapy	therapy	NN
cord-291400-o9skj94r	181	149	and	and	CC
cord-291400-o9skj94r	181	150	medical	medical	JJ
cord-291400-o9skj94r	181	151	outcomes	outcome	NNS
cord-291400-o9skj94r	181	152	for	for	IN
cord-291400-o9skj94r	181	153	hospitalized	hospitalize	VBN
cord-291400-o9skj94r	181	154	elderly	elderly	JJ
cord-291400-o9skj94r	181	155	patients	patient	NNS
cord-291400-o9skj94r	181	156	with	with	IN
cord-291400-o9skj94r	181	157	pneumonia	pneumonia	NN
cord-291400-o9skj94r	182	1	The	the	DT
cord-291400-o9skj94r	182	2	impact	impact	NN
cord-291400-o9skj94r	182	3	of	of	IN
cord-291400-o9skj94r	182	4	blood	blood	NN
cord-291400-o9skj94r	182	5	cultures	culture	NNS
cord-291400-o9skj94r	182	6	on	on	IN
cord-291400-o9skj94r	182	7	antibiotic	antibiotic	JJ
cord-291400-o9skj94r	182	8	therapy	therapy	NN
cord-291400-o9skj94r	182	9	in	in	IN
cord-291400-o9skj94r	182	10	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	182	11	pneumonia	pneumonia	NN
cord-291400-o9skj94r	182	12	Blood	blood	NN
cord-291400-o9skj94r	182	13	cultures	culture	NNS
cord-291400-o9skj94r	182	14	for	for	IN
cord-291400-o9skj94r	182	15	community	community	NN
cord-291400-o9skj94r	182	16	-	-	HYPH
cord-291400-o9skj94r	182	17	acquired	acquire	VBN
cord-291400-o9skj94r	182	18	pneumonia	pneumonia	NN
cord-291400-o9skj94r	182	19	:	:	:
cord-291400-o9skj94r	182	20	no	no	DT
cord-291400-o9skj94r	182	21	place	place	NN
cord-291400-o9skj94r	182	22	to	to	TO
cord-291400-o9skj94r	182	23	skimp	skimp	VB
cord-291400-o9skj94r	182	24	!	!	.
cord-291400-o9skj94r	183	1	Bacteremic	bacteremic	JJ
cord-291400-o9skj94r	183	2	and	and	CC
cord-291400-o9skj94r	183	3	nonbacteremic	nonbacteremic	JJ
cord-291400-o9skj94r	183	4	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	183	5	pneumonia	pneumonia	NN
cord-291400-o9skj94r	183	6	:	:	:
cord-291400-o9skj94r	183	7	a	a	DT
cord-291400-o9skj94r	183	8	prospective	prospective	JJ
cord-291400-o9skj94r	183	9	study	study	NN
cord-291400-o9skj94r	183	10	Evaluation	Evaluation	NNP
cord-291400-o9skj94r	183	11	of	of	IN
cord-291400-o9skj94r	183	12	a	a	DT
cord-291400-o9skj94r	183	13	rapid	rapid	JJ
cord-291400-o9skj94r	183	14	immunochromatographic	immunochromatographic	JJ
cord-291400-o9skj94r	183	15	test	test	NN
cord-291400-o9skj94r	183	16	for	for	IN
cord-291400-o9skj94r	183	17	detection	detection	NN
cord-291400-o9skj94r	183	18	of	of	IN
cord-291400-o9skj94r	183	19	Streptococcus	Streptococcus	NNP
cord-291400-o9skj94r	183	20	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	183	21	antigen	antigen	NN
cord-291400-o9skj94r	183	22	in	in	IN
cord-291400-o9skj94r	183	23	urine	urine	NN
cord-291400-o9skj94r	183	24	samples	sample	NNS
cord-291400-o9skj94r	183	25	from	from	IN
cord-291400-o9skj94r	183	26	adults	adult	NNS
cord-291400-o9skj94r	183	27	with	with	IN
cord-291400-o9skj94r	183	28	community	community	NN
cord-291400-o9skj94r	183	29	-	-	HYPH
cord-291400-o9skj94r	183	30	acquired	acquire	VBN
cord-291400-o9skj94r	183	31	pneumonia	pneumonia	NN
cord-291400-o9skj94r	183	32	Rapid	Rapid	NNP
cord-291400-o9skj94r	183	33	diagnosis	diagnosis	NN
cord-291400-o9skj94r	183	34	of	of	IN
cord-291400-o9skj94r	183	35	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	183	36	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	183	37	infections	infection	NNS
cord-291400-o9skj94r	183	38	in	in	IN
cord-291400-o9skj94r	183	39	adults	adult	NNS
cord-291400-o9skj94r	183	40	by	by	IN
cord-291400-o9skj94r	183	41	using	use	VBG
cord-291400-o9skj94r	183	42	the	the	DT
cord-291400-o9skj94r	183	43	Binax	Binax	NNP
cord-291400-o9skj94r	183	44	NOW	now	RB
cord-291400-o9skj94r	183	45	Streptococcus	Streptococcus	NNP
cord-291400-o9skj94r	183	46	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	183	47	urinary	urinary	JJ
cord-291400-o9skj94r	183	48	antigen	antigen	NN
cord-291400-o9skj94r	183	49	test	test	NN
cord-291400-o9skj94r	183	50	:	:	:
cord-291400-o9skj94r	183	51	a	a	DT
cord-291400-o9skj94r	183	52	prospective	prospective	NN
cord-291400-o9skj94r	183	53	,	,	,
cord-291400-o9skj94r	183	54	controlled	control	VBN
cord-291400-o9skj94r	183	55	clinical	clinical	JJ
cord-291400-o9skj94r	183	56	evaluation	evaluation	NN
cord-291400-o9skj94r	183	57	Usefulness	Usefulness	NNP
cord-291400-o9skj94r	183	58	of	of	IN
cord-291400-o9skj94r	183	59	urinary	urinary	JJ
cord-291400-o9skj94r	183	60	antigen	antigen	NN
cord-291400-o9skj94r	183	61	detection	detection	NN
cord-291400-o9skj94r	183	62	by	by	IN
cord-291400-o9skj94r	183	63	an	an	DT
cord-291400-o9skj94r	183	64	immunochromatographic	immunochromatographic	JJ
cord-291400-o9skj94r	183	65	test	test	NN
cord-291400-o9skj94r	183	66	for	for	IN
cord-291400-o9skj94r	183	67	diagnosis	diagnosis	NN
cord-291400-o9skj94r	183	68	of	of	IN
cord-291400-o9skj94r	183	69	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	183	70	pneumonia	pneumonia	NN
cord-291400-o9skj94r	183	71	in	in	IN
cord-291400-o9skj94r	183	72	children	child	NNS
cord-291400-o9skj94r	183	73	Evaluation	Evaluation	NNP
cord-291400-o9skj94r	183	74	of	of	IN
cord-291400-o9skj94r	183	75	the	the	DT
cord-291400-o9skj94r	183	76	immunochromatographic	immunochromatographic	JJ
cord-291400-o9skj94r	183	77	Binax	Binax	NNP
cord-291400-o9skj94r	183	78	NOW	now	RB
cord-291400-o9skj94r	183	79	assay	assay	NN
cord-291400-o9skj94r	183	80	for	for	IN
cord-291400-o9skj94r	183	81	detection	detection	NN
cord-291400-o9skj94r	183	82	of	of	IN
cord-291400-o9skj94r	183	83	Streptococcus	Streptococcus	NNP
cord-291400-o9skj94r	183	84	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	183	85	urinary	urinary	JJ
cord-291400-o9skj94r	183	86	antigen	antigen	NN
cord-291400-o9skj94r	183	87	in	in	IN
cord-291400-o9skj94r	183	88	a	a	DT
cord-291400-o9skj94r	183	89	prospective	prospective	JJ
cord-291400-o9skj94r	183	90	study	study	NN
cord-291400-o9skj94r	183	91	of	of	IN
cord-291400-o9skj94r	183	92	community	community	NN
cord-291400-o9skj94r	183	93	-	-	HYPH
cord-291400-o9skj94r	183	94	acquired	acquire	VBN
cord-291400-o9skj94r	183	95	pneumonia	pneumonia	NN
cord-291400-o9skj94r	183	96	in	in	IN
cord-291400-o9skj94r	183	97	Spain	Spain	NNP
cord-291400-o9skj94r	183	98	Deaths	Deaths	NNP
cord-291400-o9skj94r	183	99	in	in	IN
cord-291400-o9skj94r	183	100	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	183	101	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	183	102	pneumonia	pneumonia	NN
cord-291400-o9skj94r	183	103	:	:	:
cord-291400-o9skj94r	183	104	a	a	DT
cord-291400-o9skj94r	183	105	comparison	comparison	NN
cord-291400-o9skj94r	183	106	of	of	IN
cord-291400-o9skj94r	183	107	two	two	CD
cord-291400-o9skj94r	183	108	populations	population	NNS
cord-291400-o9skj94r	183	109	Bacteremic	Bacteremic	NNP
cord-291400-o9skj94r	183	110	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	183	111	pneumonia	pneumonia	NN
cord-291400-o9skj94r	183	112	mortality	mortality	NN
cord-291400-o9skj94r	183	113	rate	rate	NN
cord-291400-o9skj94r	183	114	:	:	:
cord-291400-o9skj94r	183	115	is	be	VBZ
cord-291400-o9skj94r	183	116	it	-PRON-	PRP
cord-291400-o9skj94r	183	117	really	really	RB
cord-291400-o9skj94r	183	118	different	different	JJ
cord-291400-o9skj94r	183	119	in	in	IN
cord-291400-o9skj94r	183	120	Sweden	Sweden	NNP
cord-291400-o9skj94r	183	121	?	?	.
cord-291400-o9skj94r	184	1	Lack	lack	NN
cord-291400-o9skj94r	184	2	of	of	IN
cord-291400-o9skj94r	184	3	synergy	synergy	NN
cord-291400-o9skj94r	184	4	of	of	IN
cord-291400-o9skj94r	184	5	erythromycin	erythromycin	NN
cord-291400-o9skj94r	184	6	combined	combine	VBN
cord-291400-o9skj94r	184	7	with	with	IN
cord-291400-o9skj94r	184	8	penicillin	penicillin	NN
cord-291400-o9skj94r	184	9	or	or	CC
cord-291400-o9skj94r	184	10	cefotaxime	cefotaxime	NN
cord-291400-o9skj94r	184	11	against	against	IN
cord-291400-o9skj94r	184	12	Streptococcus	Streptococcus	NNP
cord-291400-o9skj94r	184	13	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	184	14	in	in	IN
cord-291400-o9skj94r	184	15	vitro	vitro	FW
cord-291400-o9skj94r	184	16	Treatment	treatment	NN
cord-291400-o9skj94r	184	17	of	of	IN
cord-291400-o9skj94r	184	18	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	184	19	meningitis	meningitis	NN
cord-291400-o9skj94r	184	20	with	with	IN
cord-291400-o9skj94r	184	21	penicillin	penicillin	NN
cord-291400-o9skj94r	184	22	compared	compare	VBN
cord-291400-o9skj94r	184	23	with	with	IN
cord-291400-o9skj94r	184	24	penicillin	penicillin	NN
cord-291400-o9skj94r	184	25	and	and	CC
cord-291400-o9skj94r	184	26	aureomycin	aureomycin	NNS
cord-291400-o9skj94r	184	27	;	;	,
cord-291400-o9skj94r	184	28	studies	study	NNS
cord-291400-o9skj94r	184	29	including	include	VBG
cord-291400-o9skj94r	184	30	observations	observation	NNS
cord-291400-o9skj94r	184	31	on	on	IN
cord-291400-o9skj94r	184	32	an	an	DT
cord-291400-o9skj94r	184	33	apparent	apparent	JJ
cord-291400-o9skj94r	184	34	antagonism	antagonism	NN
cord-291400-o9skj94r	184	35	between	between	IN
cord-291400-o9skj94r	184	36	penicillin	penicillin	NN
cord-291400-o9skj94r	184	37	and	and	CC
cord-291400-o9skj94r	184	38	aureomycin	aureomycin	VBZ
cord-291400-o9skj94r	184	39	Prospective	prospective	JJ
cord-291400-o9skj94r	184	40	observational	observational	JJ
cord-291400-o9skj94r	184	41	study	study	NN
cord-291400-o9skj94r	184	42	of	of	IN
cord-291400-o9skj94r	184	43	bacteremic	bacteremic	NNP
cord-291400-o9skj94r	184	44	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	184	45	pneumonia	pneumonia	NN
cord-291400-o9skj94r	184	46	:	:	:
cord-291400-o9skj94r	184	47	effect	effect	NN
cord-291400-o9skj94r	184	48	of	of	IN
cord-291400-o9skj94r	184	49	discordant	discordant	JJ
cord-291400-o9skj94r	184	50	therapy	therapy	NN
cord-291400-o9skj94r	184	51	on	on	IN
cord-291400-o9skj94r	184	52	mortality	mortality	NN
cord-291400-o9skj94r	184	53	Potential	potential	JJ
cord-291400-o9skj94r	184	54	importance	importance	NN
cord-291400-o9skj94r	184	55	of	of	IN
cord-291400-o9skj94r	184	56	Legionella	Legionella	NNP
cord-291400-o9skj94r	184	57	species	specie	NNS
cord-291400-o9skj94r	184	58	in	in	IN
cord-291400-o9skj94r	184	59	community	community	NN
cord-291400-o9skj94r	184	60	acquired	acquire	VBD
cord-291400-o9skj94r	184	61	pneumonia	pneumonia	NN
cord-291400-o9skj94r	184	62	CAP	cap	NN
cord-291400-o9skj94r	184	63	Infection	infection	NN
cord-291400-o9skj94r	184	64	due	due	JJ
cord-291400-o9skj94r	184	65	to	to	IN
cord-291400-o9skj94r	184	66	Legionella	Legionella	NNP
cord-291400-o9skj94r	184	67	species	specie	NNS
cord-291400-o9skj94r	184	68	other	other	JJ
cord-291400-o9skj94r	184	69	than	than	IN
cord-291400-o9skj94r	184	70	L.	L.	NNP
cord-291400-o9skj94r	184	71	pneuophila	pneuophila	NNP
cord-291400-o9skj94r	184	72	Legionella	Legionella	NNP
cord-291400-o9skj94r	184	73	drozanskii	drozanskii	NNP
cord-291400-o9skj94r	184	74	sp	sp	NNP
cord-291400-o9skj94r	184	75	nov	nov	NNP
cord-291400-o9skj94r	184	76	,	,	,
cord-291400-o9skj94r	184	77	Legionella	Legionella	NNP
cord-291400-o9skj94r	184	78	rowbothamii	rowbothamii	NNP
cord-291400-o9skj94r	184	79	sp	sp	NNP
cord-291400-o9skj94r	184	80	nov	nov	NNP
cord-291400-o9skj94r	184	81	and	and	CC
cord-291400-o9skj94r	184	82	Legionella	Legionella	NNP
cord-291400-o9skj94r	184	83	fallonii	fallonii	NNP
cord-291400-o9skj94r	184	84	sp	sp	NNP
cord-291400-o9skj94r	185	1	nov	nov	NNP
cord-291400-o9skj94r	185	2	:	:	:
cord-291400-o9skj94r	186	1	three	three	CD
cord-291400-o9skj94r	186	2	new	new	JJ
cord-291400-o9skj94r	186	3	unusual	unusual	JJ
cord-291400-o9skj94r	186	4	Legionella	Legionella	NNP
cord-291400-o9skj94r	186	5	species	specie	NNS
cord-291400-o9skj94r	186	6	Legionella	Legionella	NNP
cord-291400-o9skj94r	186	7	-	-	HYPH
cord-291400-o9skj94r	186	8	like	like	JJ
cord-291400-o9skj94r	186	9	and	and	CC
cord-291400-o9skj94r	186	10	other	other	JJ
cord-291400-o9skj94r	186	11	amoebal	amoebal	JJ
cord-291400-o9skj94r	186	12	pathogens	pathogen	NNS
cord-291400-o9skj94r	186	13	as	as	IN
cord-291400-o9skj94r	186	14	agents	agent	NNS
cord-291400-o9skj94r	186	15	of	of	IN
cord-291400-o9skj94r	186	16	community	community	NN
cord-291400-o9skj94r	186	17	-	-	HYPH
cord-291400-o9skj94r	186	18	acquired	acquire	VBN
cord-291400-o9skj94r	186	19	pneumonia	pneumonia	NN
cord-291400-o9skj94r	186	20	and	and	CC
cord-291400-o9skj94r	186	21	the	the	DT
cord-291400-o9skj94r	186	22	Methylprednisolone	Methylprednisolone	NNP
cord-291400-o9skj94r	186	23	Severe	Severe	NNP
cord-291400-o9skj94r	186	24	Sepsis	Sepsis	NNP
cord-291400-o9skj94r	186	25	Study	Study	NNP
cord-291400-o9skj94r	186	26	Group	Group	NNP
cord-291400-o9skj94r	186	27	:	:	:
cord-291400-o9skj94r	186	28	a	a	DT
cord-291400-o9skj94r	186	29	controlled	control	VBN
cord-291400-o9skj94r	186	30	clinical	clinical	JJ
cord-291400-o9skj94r	186	31	trial	trial	NN
cord-291400-o9skj94r	186	32	of	of	IN
cord-291400-o9skj94r	186	33	high	high	JJ
cord-291400-o9skj94r	186	34	-	-	HYPH
cord-291400-o9skj94r	186	35	dose	dose	NN
cord-291400-o9skj94r	186	36	methylprednisolone	methylprednisolone	NN
cord-291400-o9skj94r	186	37	in	in	IN
cord-291400-o9skj94r	186	38	the	the	DT
cord-291400-o9skj94r	186	39	treatment	treatment	NN
cord-291400-o9skj94r	186	40	of	of	IN
cord-291400-o9skj94r	186	41	severe	severe	JJ
cord-291400-o9skj94r	186	42	sepsis	sepsis	NN
cord-291400-o9skj94r	186	43	and	and	CC
cord-291400-o9skj94r	186	44	septic	septic	JJ
cord-291400-o9skj94r	186	45	shock	shock	NN
cord-291400-o9skj94r	186	46	A	a	DT
cord-291400-o9skj94r	186	47	controlled	control	VBN
cord-291400-o9skj94r	186	48	clinical	clinical	JJ
cord-291400-o9skj94r	186	49	trial	trial	NN
cord-291400-o9skj94r	186	50	of	of	IN
cord-291400-o9skj94r	186	51	E5	E5	NNP
cord-291400-o9skj94r	186	52	murine	murine	JJ
cord-291400-o9skj94r	186	53	monoclonal	monoclonal	JJ
cord-291400-o9skj94r	186	54	IgM	IgM	NNP
cord-291400-o9skj94r	186	55	antibody	antibody	NN
cord-291400-o9skj94r	186	56	to	to	TO
cord-291400-o9skj94r	186	57	endotoxin	endotoxin	VB
cord-291400-o9skj94r	186	58	in	in	IN
cord-291400-o9skj94r	186	59	the	the	DT
cord-291400-o9skj94r	186	60	treatment	treatment	NN
cord-291400-o9skj94r	186	61	of	of	IN
cord-291400-o9skj94r	186	62	gram	gram	NN
cord-291400-o9skj94r	186	63	-	-	HYPH
cord-291400-o9skj94r	186	64	negative	negative	JJ
cord-291400-o9skj94r	186	65	sepsis	sepsis	NN
cord-291400-o9skj94r	186	66	Efficacy	efficacy	NN
cord-291400-o9skj94r	186	67	and	and	CC
cord-291400-o9skj94r	186	68	safety	safety	NN
cord-291400-o9skj94r	186	69	of	of	IN
cord-291400-o9skj94r	186	70	monoclonal	monoclonal	JJ
cord-291400-o9skj94r	186	71	antibody	antibody	NN
cord-291400-o9skj94r	186	72	to	to	IN
cord-291400-o9skj94r	186	73	human	human	JJ
cord-291400-o9skj94r	186	74	tumor	tumor	NN
cord-291400-o9skj94r	186	75	necrosis	necrosis	NN
cord-291400-o9skj94r	186	76	factor	factor	NN
cord-291400-o9skj94r	186	77	in	in	IN
cord-291400-o9skj94r	186	78	patients	patient	NNS
cord-291400-o9skj94r	186	79	with	with	IN
cord-291400-o9skj94r	186	80	sepsis	sepsis	NN
cord-291400-o9skj94r	186	81	syndrome	syndrome	NN
cord-291400-o9skj94r	186	82	:	:	:
cord-291400-o9skj94r	186	83	a	a	DT
cord-291400-o9skj94r	186	84	randomized	randomized	JJ
cord-291400-o9skj94r	186	85	,	,	,
cord-291400-o9skj94r	186	86	controlled	control	VBN
cord-291400-o9skj94r	186	87	,	,	,
cord-291400-o9skj94r	186	88	double	double	JJ
cord-291400-o9skj94r	186	89	-	-	HYPH
cord-291400-o9skj94r	186	90	blind	blind	JJ
cord-291400-o9skj94r	186	91	,	,	,
cord-291400-o9skj94r	186	92	multicenter	multicenter	JJ
cord-291400-o9skj94r	186	93	clinical	clinical	JJ
cord-291400-o9skj94r	186	94	trial	trial	NN
cord-291400-o9skj94r	186	95	A	a	DT
cord-291400-o9skj94r	186	96	second	second	JJ
cord-291400-o9skj94r	186	97	large	large	JJ
cord-291400-o9skj94r	186	98	controlled	control	VBN
cord-291400-o9skj94r	186	99	clinical	clinical	JJ
cord-291400-o9skj94r	186	100	study	study	NN
cord-291400-o9skj94r	186	101	of	of	IN
cord-291400-o9skj94r	186	102	E5	E5	NNP
cord-291400-o9skj94r	186	103	,	,	,
cord-291400-o9skj94r	186	104	a	a	DT
cord-291400-o9skj94r	186	105	monoclonal	monoclonal	JJ
cord-291400-o9skj94r	186	106	antibody	antibody	NN
cord-291400-o9skj94r	186	107	to	to	IN
cord-291400-o9skj94r	186	108	endotoxin	endotoxin	NN
cord-291400-o9skj94r	186	109	:	:	:
cord-291400-o9skj94r	186	110	results	result	NNS
cord-291400-o9skj94r	186	111	of	of	IN
cord-291400-o9skj94r	186	112	a	a	DT
cord-291400-o9skj94r	186	113	prospective	prospective	JJ
cord-291400-o9skj94r	186	114	,	,	,
cord-291400-o9skj94r	186	115	multicenter	multicenter	JJ
cord-291400-o9skj94r	186	116	,	,	,
cord-291400-o9skj94r	186	117	randomized	randomized	JJ
cord-291400-o9skj94r	186	118	,	,	,
cord-291400-o9skj94r	186	119	controlled	control	VBN
cord-291400-o9skj94r	186	120	trial	trial	NN
cord-291400-o9skj94r	186	121	The	the	DT
cord-291400-o9skj94r	186	122	beneficial	beneficial	JJ
cord-291400-o9skj94r	186	123	effects	effect	NNS
cord-291400-o9skj94r	186	124	of	of	IN
cord-291400-o9skj94r	186	125	early	early	JJ
cord-291400-o9skj94r	186	126	dexamethasone	dexamethasone	NNP
cord-291400-o9skj94r	186	127	administration	administration	NN
cord-291400-o9skj94r	186	128	in	in	IN
cord-291400-o9skj94r	186	129	infants	infant	NNS
cord-291400-o9skj94r	186	130	and	and	CC
cord-291400-o9skj94r	186	131	children	child	NNS
cord-291400-o9skj94r	186	132	with	with	IN
cord-291400-o9skj94r	186	133	bacterial	bacterial	JJ
cord-291400-o9skj94r	186	134	meningitis	meningitis	NN
cord-291400-o9skj94r	186	135	European	european	JJ
cord-291400-o9skj94r	186	136	dexamethasone	dexamethasone	NN
cord-291400-o9skj94r	186	137	in	in	IN
cord-291400-o9skj94r	186	138	adulthood	adulthood	NN
cord-291400-o9skj94r	187	1	bacterial	bacterial	JJ
cord-291400-o9skj94r	187	2	meningitis	meningitis	NN
cord-291400-o9skj94r	187	3	study	study	NN
cord-291400-o9skj94r	187	4	investigators	investigator	NNS
cord-291400-o9skj94r	187	5	:	:	:
cord-291400-o9skj94r	188	1	dexamethasone	dexamethasone	NN
cord-291400-o9skj94r	188	2	in	in	IN
cord-291400-o9skj94r	188	3	adults	adult	NNS
cord-291400-o9skj94r	188	4	with	with	IN
cord-291400-o9skj94r	188	5	bacterial	bacterial	JJ
cord-291400-o9skj94r	188	6	meningitis	meningitis	NN
cord-291400-o9skj94r	188	7	Anti	anti	JJ
cord-291400-o9skj94r	188	8	-	-	JJ
cord-291400-o9skj94r	188	9	tumor	tumor	JJ
cord-291400-o9skj94r	188	10	necrosis	necrosis	NN
cord-291400-o9skj94r	188	11	factor	factor	NN
cord-291400-o9skj94r	188	12	antibody	antibody	NN
cord-291400-o9skj94r	188	13	impairs	impair	VBZ
cord-291400-o9skj94r	188	14	the	the	DT
cord-291400-o9skj94r	188	15	therapeutic	therapeutic	JJ
cord-291400-o9skj94r	188	16	effect	effect	NN
cord-291400-o9skj94r	188	17	of	of	IN
cord-291400-o9skj94r	188	18	ceftriaxone	ceftriaxone	NN
cord-291400-o9skj94r	188	19	in	in	IN
cord-291400-o9skj94r	188	20	murine	murine	JJ
cord-291400-o9skj94r	188	21	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	188	22	pneumonia	pneumonia	NN
cord-291400-o9skj94r	189	1	Is	be	VBZ
cord-291400-o9skj94r	189	2	anti	anti	JJ
cord-291400-o9skj94r	189	3	-	-	JJ
cord-291400-o9skj94r	189	4	tumor	tumor	JJ
cord-291400-o9skj94r	189	5	necrosis	necrosis	NN
cord-291400-o9skj94r	189	6	factor	factor	NN
cord-291400-o9skj94r	189	7	therapy	therapy	NN
cord-291400-o9skj94r	189	8	associated	associate	VBN
cord-291400-o9skj94r	189	9	with	with	IN
cord-291400-o9skj94r	189	10	increased	increase	VBN
cord-291400-o9skj94r	189	11	mortality	mortality	NN
cord-291400-o9skj94r	189	12	in	in	IN
cord-291400-o9skj94r	189	13	patients	patient	NNS
cord-291400-o9skj94r	189	14	with	with	IN
cord-291400-o9skj94r	189	15	severe	severe	JJ
cord-291400-o9skj94r	189	16	sepsis	sepsis	NN
cord-291400-o9skj94r	189	17	caused	cause	VBN
cord-291400-o9skj94r	189	18	by	by	IN
cord-291400-o9skj94r	189	19	pneumonia	pneumonia	NN
cord-291400-o9skj94r	189	20	?	?	.
cord-291400-o9skj94r	190	1	Activation	activation	NN
cord-291400-o9skj94r	190	2	of	of	IN
cord-291400-o9skj94r	190	3	neutrophils	neutrophil	NNS
cord-291400-o9skj94r	190	4	and	and	CC
cord-291400-o9skj94r	190	5	inhibition	inhibition	NN
cord-291400-o9skj94r	190	6	of	of	IN
cord-291400-o9skj94r	190	7	the	the	DT
cord-291400-o9skj94r	190	8	proinflammatory	proinflammatory	JJ
cord-291400-o9skj94r	190	9	cytokine	cytokine	NN
cord-291400-o9skj94r	190	10	response	response	NN
cord-291400-o9skj94r	190	11	by	by	IN
cord-291400-o9skj94r	190	12	endogenous	endogenous	JJ
cord-291400-o9skj94r	190	13	granulocyte	granulocyte	NN
cord-291400-o9skj94r	190	14	colony	colony	NN
cord-291400-o9skj94r	190	15	stimulating	stimulate	VBG
cord-291400-o9skj94r	190	16	factor	factor	NN
cord-291400-o9skj94r	190	17	in	in	IN
cord-291400-o9skj94r	190	18	murine	murine	JJ
cord-291400-o9skj94r	190	19	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	190	20	pneumonia	pneumonia	NN
cord-291400-o9skj94r	190	21	Drug	drug	NN
cord-291400-o9skj94r	190	22	-	-	HYPH
cord-291400-o9skj94r	190	23	resistant	resistant	JJ
cord-291400-o9skj94r	190	24	Streptococcus	Streptococcus	NNP
cord-291400-o9skj94r	190	25	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	190	26	TRUST	TRUST	NNP
cord-291400-o9skj94r	190	27	Surveillance	Surveillance	NNP
cord-291400-o9skj94r	190	28	Program	Program	NNP
cord-291400-o9skj94r	190	29	.	.	.
cord-291400-o9skj94r	191	1	Factors	factor	NNS
cord-291400-o9skj94r	191	2	associated	associate	VBN
cord-291400-o9skj94r	191	3	with	with	IN
cord-291400-o9skj94r	191	4	relative	relative	JJ
cord-291400-o9skj94r	191	5	rates	rate	NNS
cord-291400-o9skj94r	191	6	of	of	IN
cord-291400-o9skj94r	191	7	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	191	8	resistance	resistance	NN
cord-291400-o9skj94r	191	9	among	among	IN
cord-291400-o9skj94r	191	10	Streptococcus	streptococcus	NN
cord-291400-o9skj94r	191	11	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	191	12	in	in	IN
cord-291400-o9skj94r	191	13	the	the	DT
cord-291400-o9skj94r	191	14	United	United	NNP
cord-291400-o9skj94r	191	15	States	States	NNP
cord-291400-o9skj94r	191	16	:	:	:
cord-291400-o9skj94r	191	17	results	result	NNS
cord-291400-o9skj94r	191	18	from	from	IN
cord-291400-o9skj94r	191	19	the	the	DT
cord-291400-o9skj94r	191	20	TRUST	TRUST	NNP
cord-291400-o9skj94r	191	21	Surveillance	Surveillance	NNP
cord-291400-o9skj94r	191	22	Program	Program	NNP
cord-291400-o9skj94r	191	23	Influence	influence	NN
cord-291400-o9skj94r	191	24	of	of	IN
cord-291400-o9skj94r	191	25	patient	patient	JJ
cord-291400-o9skj94r	191	26	age	age	NN
cord-291400-o9skj94r	191	27	on	on	IN
cord-291400-o9skj94r	191	28	the	the	DT
cord-291400-o9skj94r	191	29	susceptibility	susceptibility	NN
cord-291400-o9skj94r	191	30	patterns	pattern	NNS
cord-291400-o9skj94r	191	31	of	of	IN
cord-291400-o9skj94r	191	32	Streptococcus	streptococcus	NN
cord-291400-o9skj94r	191	33	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	191	34	isolates	isolate	VBZ
cord-291400-o9skj94r	191	35	in	in	IN
cord-291400-o9skj94r	191	36	North	North	NNP
cord-291400-o9skj94r	191	37	America	America	NNP
cord-291400-o9skj94r	191	38	International	International	NNP
cord-291400-o9skj94r	191	39	Pneumococcal	Pneumococcal	NNP
cord-291400-o9skj94r	191	40	Study	Study	NNP
cord-291400-o9skj94r	191	41	Group	Group	NNP
cord-291400-o9skj94r	191	42	:	:	:
cord-291400-o9skj94r	191	43	an	an	DT
cord-291400-o9skj94r	191	44	international	international	JJ
cord-291400-o9skj94r	191	45	prospective	prospective	JJ
cord-291400-o9skj94r	191	46	study	study	NN
cord-291400-o9skj94r	191	47	of	of	IN
cord-291400-o9skj94r	191	48	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	191	49	bacteremia	bacteremia	NN
cord-291400-o9skj94r	191	50	.	.	.
cord-291400-o9skj94r	192	1	Correlation	correlation	NN
cord-291400-o9skj94r	192	2	with	with	IN
cord-291400-o9skj94r	192	3	in	in	FW
cord-291400-o9skj94r	192	4	vitro	vitro	FW
cord-291400-o9skj94r	192	5	resistance	resistance	NN
cord-291400-o9skj94r	192	6	,	,	,
cord-291400-o9skj94r	192	7	antibiotics	antibiotic	NNS
cord-291400-o9skj94r	192	8	administered	administer	VBN
cord-291400-o9skj94r	192	9	,	,	,
cord-291400-o9skj94r	192	10	and	and	CC
cord-291400-o9skj94r	192	11	clinical	clinical	JJ
cord-291400-o9skj94r	192	12	outcome	outcome	NN
cord-291400-o9skj94r	192	13	Is	be	VBZ
cord-291400-o9skj94r	192	14	azithromycin	azithromycin	NN
cord-291400-o9skj94r	192	15	the	the	DT
cord-291400-o9skj94r	192	16	first	first	JJ
cord-291400-o9skj94r	192	17	-	-	HYPH
cord-291400-o9skj94r	192	18	choice	choice	NN
cord-291400-o9skj94r	192	19	macrolide	macrolide	NN
cord-291400-o9skj94r	192	20	for	for	IN
cord-291400-o9skj94r	192	21	treatment	treatment	NN
cord-291400-o9skj94r	192	22	of	of	IN
cord-291400-o9skj94r	192	23	community	community	NN
cord-291400-o9skj94r	192	24	-	-	HYPH
cord-291400-o9skj94r	192	25	acquired	acquire	VBN
cord-291400-o9skj94r	192	26	pneumonia	pneumonia	NN
cord-291400-o9skj94r	192	27	?	?	.
cord-291400-o9skj94r	193	1	The	the	DT
cord-291400-o9skj94r	193	2	best	good	JJS
cord-291400-o9skj94r	193	3	treatment	treatment	NN
cord-291400-o9skj94r	193	4	of	of	IN
cord-291400-o9skj94r	193	5	pneumonia	pneumonia	NN
cord-291400-o9skj94r	193	6	:	:	:
cord-291400-o9skj94r	193	7	new	new	JJ
cord-291400-o9skj94r	193	8	clues	clue	NNS
cord-291400-o9skj94r	193	9	,	,	,
cord-291400-o9skj94r	193	10	but	but	CC
cord-291400-o9skj94r	193	11	no	no	DT
cord-291400-o9skj94r	193	12	definitive	definitive	JJ
cord-291400-o9skj94r	193	13	answers	answer	NNS
cord-291400-o9skj94r	193	14	What	what	WP
cord-291400-o9skj94r	193	15	is	be	VBZ
cord-291400-o9skj94r	193	16	optimal	optimal	JJ
cord-291400-o9skj94r	193	17	therapy	therapy	NN
cord-291400-o9skj94r	193	18	for	for	IN
cord-291400-o9skj94r	193	19	bacteremic	bacteremic	JJ
cord-291400-o9skj94r	193	20	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	193	21	pneumonia	pneumonia	NN
cord-291400-o9skj94r	193	22	?	?	.
cord-291400-o9skj94r	194	1	Monotherapy	Monotherapy	NNP
cord-291400-o9skj94r	194	2	versus	versus	IN
cord-291400-o9skj94r	194	3	dual	dual	JJ
cord-291400-o9skj94r	194	4	therapy	therapy	NN
cord-291400-o9skj94r	194	5	for	for	IN
cord-291400-o9skj94r	194	6	community	community	NN
cord-291400-o9skj94r	194	7	-	-	HYPH
cord-291400-o9skj94r	194	8	acquired	acquire	VBN
cord-291400-o9skj94r	194	9	pneumonia	pneumonia	NN
cord-291400-o9skj94r	194	10	in	in	IN
cord-291400-o9skj94r	194	11	hospitalized	hospitalize	VBN
cord-291400-o9skj94r	194	12	patients	patient	NNS
cord-291400-o9skj94r	194	13	Synergy	Synergy	NNP
cord-291400-o9skj94r	194	14	between	between	IN
cord-291400-o9skj94r	194	15	amoxicillin	amoxicillin	NNP
cord-291400-o9skj94r	194	16	and	and	CC
cord-291400-o9skj94r	194	17	gentamicin	gentamicin	NNP
cord-291400-o9skj94r	194	18	in	in	IN
cord-291400-o9skj94r	194	19	combination	combination	NN
cord-291400-o9skj94r	194	20	against	against	IN
cord-291400-o9skj94r	194	21	a	a	DT
cord-291400-o9skj94r	194	22	highly	highly	RB
cord-291400-o9skj94r	194	23	penicillin	penicillin	NN
cord-291400-o9skj94r	194	24	-	-	HYPH
cord-291400-o9skj94r	194	25	resistant	resistant	JJ
cord-291400-o9skj94r	194	26	and	and	CC
cord-291400-o9skj94r	194	27	-tolerant	-tolerant	JJ
cord-291400-o9skj94r	194	28	strain	strain	NN
cord-291400-o9skj94r	194	29	of	of	IN
cord-291400-o9skj94r	194	30	Streptococcus	streptococcus	NN
cord-291400-o9skj94r	194	31	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	194	32	in	in	IN
cord-291400-o9skj94r	194	33	a	a	DT
cord-291400-o9skj94r	194	34	mouse	mouse	NN
cord-291400-o9skj94r	194	35	neumonia	neumonia	NNP
cord-291400-o9skj94r	194	36	model	model	NNP
cord-291400-o9skj94r	194	37	Effective	effective	JJ
cord-291400-o9skj94r	194	38	combination	combination	NN
cord-291400-o9skj94r	194	39	therapy	therapy	NN
cord-291400-o9skj94r	194	40	for	for	IN
cord-291400-o9skj94r	194	41	invasive	invasive	JJ
cord-291400-o9skj94r	194	42	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	194	43	pneumonia	pneumonia	NN
cord-291400-o9skj94r	194	44	with	with	IN
cord-291400-o9skj94r	194	45	ampicillin	ampicillin	NN
cord-291400-o9skj94r	194	46	and	and	CC
cord-291400-o9skj94r	194	47	intravenous	intravenous	JJ
cord-291400-o9skj94r	194	48	immunoglobulins	immunoglobulin	NNS
cord-291400-o9skj94r	194	49	in	in	IN
cord-291400-o9skj94r	194	50	a	a	DT
cord-291400-o9skj94r	194	51	mouse	mouse	NN
cord-291400-o9skj94r	194	52	model	model	NN
cord-291400-o9skj94r	195	1	TNF	tnf	NN
cord-291400-o9skj94r	195	2	-	-	HYPH
cord-291400-o9skj94r	195	3	alpha	alpha	NN
cord-291400-o9skj94r	195	4	compensates	compensate	VBZ
cord-291400-o9skj94r	195	5	for	for	IN
cord-291400-o9skj94r	195	6	the	the	DT
cord-291400-o9skj94r	195	7	impaired	impaired	JJ
cord-291400-o9skj94r	195	8	host	host	NN
cord-291400-o9skj94r	195	9	defense	defense	NN
cord-291400-o9skj94r	195	10	of	of	IN
cord-291400-o9skj94r	195	11	IL-1	IL-1	NNP
cord-291400-o9skj94r	195	12	type	type	NN
cord-291400-o9skj94r	196	1	I	-PRON-	PRP
cord-291400-o9skj94r	196	2	receptor	receptor	NN
cord-291400-o9skj94r	196	3	-	-	HYPH
cord-291400-o9skj94r	196	4	deficient	deficient	JJ
cord-291400-o9skj94r	196	5	mice	mouse	NNS
cord-291400-o9skj94r	196	6	during	during	IN
cord-291400-o9skj94r	196	7	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	196	8	pneumonia	pneumonia	NN
cord-291400-o9skj94r	196	9	Interleukin-6	Interleukin-6	.
cord-291400-o9skj94r	197	1	gene	gene	NN
cord-291400-o9skj94r	197	2	-	-	HYPH
cord-291400-o9skj94r	197	3	deficient	deficient	JJ
cord-291400-o9skj94r	197	4	mice	mouse	NNS
cord-291400-o9skj94r	197	5	show	show	VBP
cord-291400-o9skj94r	197	6	impaired	impaired	JJ
cord-291400-o9skj94r	197	7	defense	defense	NN
cord-291400-o9skj94r	197	8	against	against	IN
cord-291400-o9skj94r	197	9	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	197	10	pneumonia	pneumonia	NN
cord-291400-o9skj94r	197	11	IL-18	IL-18	NNP
cord-291400-o9skj94r	197	12	improves	improve	VBZ
cord-291400-o9skj94r	197	13	the	the	DT
cord-291400-o9skj94r	197	14	early	early	JJ
cord-291400-o9skj94r	197	15	antimicrobial	antimicrobial	JJ
cord-291400-o9skj94r	197	16	host	host	NN
cord-291400-o9skj94r	197	17	response	response	NN
cord-291400-o9skj94r	197	18	to	to	IN
cord-291400-o9skj94r	197	19	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	197	20	pneumonia	pneumonia	NN
cord-291400-o9skj94r	197	21	Alveolar	alveolar	NN
cord-291400-o9skj94r	197	22	macrophages	macrophage	NNS
cord-291400-o9skj94r	197	23	have	have	VBP
cord-291400-o9skj94r	197	24	a	a	DT
cord-291400-o9skj94r	197	25	protective	protective	JJ
cord-291400-o9skj94r	197	26	antiinflammatory	antiinflammatory	JJ
cord-291400-o9skj94r	197	27	role	role	NN
cord-291400-o9skj94r	197	28	during	during	IN
cord-291400-o9skj94r	197	29	murine	murine	JJ
cord-291400-o9skj94r	197	30	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	197	31	pneumonia	pneumonia	NN
cord-291400-o9skj94r	197	32	Improved	improve	VBD
cord-291400-o9skj94r	197	33	host	host	NN
cord-291400-o9skj94r	197	34	defense	defense	NN
cord-291400-o9skj94r	197	35	against	against	IN
cord-291400-o9skj94r	197	36	pneumococcal	pneumococcal	JJ
cord-291400-o9skj94r	197	37	pneumonia	pneumonia	NN
cord-291400-o9skj94r	197	38	in	in	IN
cord-291400-o9skj94r	197	39	platelet	platelet	NN
cord-291400-o9skj94r	197	40	-	-	HYPH
cord-291400-o9skj94r	197	41	activating	activate	VBG
cord-291400-o9skj94r	197	42	factor	factor	NN
cord-291400-o9skj94r	197	43	receptor	receptor	NN
cord-291400-o9skj94r	197	44	-	-	HYPH
cord-291400-o9skj94r	197	45	deficient	deficient	JJ
cord-291400-o9skj94r	197	46	mice	mouse	NNS
cord-291400-o9skj94r	197	47	ZmpB	ZmpB	NNP
cord-291400-o9skj94r	197	48	,	,	,
cord-291400-o9skj94r	197	49	a	a	DT
cord-291400-o9skj94r	197	50	novel	novel	JJ
cord-291400-o9skj94r	197	51	virulence	virulence	NN
cord-291400-o9skj94r	197	52	factor	factor	NN
cord-291400-o9skj94r	197	53	of	of	IN
cord-291400-o9skj94r	197	54	Streptococcus	streptococcus	NN
cord-291400-o9skj94r	197	55	pneumoniae	pneumoniae	NN
cord-291400-o9skj94r	197	56	that	that	WDT
cord-291400-o9skj94r	197	57	induces	induce	VBZ
cord-291400-o9skj94r	197	58	tumor	tumor	NN
cord-291400-o9skj94r	197	59	necrosis	necrosis	NN
cord-291400-o9skj94r	197	60	factor	factor	NN
cord-291400-o9skj94r	197	61	alpha	alpha	NN
cord-291400-o9skj94r	197	62	production	production	NN
cord-291400-o9skj94r	197	63	in	in	IN
cord-291400-o9skj94r	197	64	the	the	DT
cord-291400-o9skj94r	197	65	respiratory	respiratory	JJ
cord-291400-o9skj94r	197	66	tract	tract	NN