id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-291400-o9skj94r	Plouffe, Joseph F.	Re-evaluation of the therapy of severe pneumonia caused by Streptococcus pneumoniae	2004-12-31		.txt	text/plain	4416	244	39	Several retrospective reviews of bacteremic pneumococcal pneumonia suggest that dual therapy with a beta-lactam and a macrolide antimicrobial agent is associated with a lower case fatality rate than therapy with a beta-lactam alone. With the advent of modern microbiology, Streptococcus pneumoniae (pneumococcus) was identified as the cause of community-acquired pneumonia (CAP) in the most patients [1] . Changes that have been associated with improvements in CFR in some series of patients with CAP include more rapid antibiotic delivery [31] , combination therapy with a cephalosporin with good pneumococcal activity and macrolide (versus the cephalosporin alone), and therapy with a fluoroquinolone (ciprofloxacin; versus a cephalosporin alone) [32] . A previous study of patients with CAP, but not nonbacteremic pneumococcal pneumonia, found that treated with blactamase inhibitors and a macrolide were less effective than treatment with a cephalosporin alone [32] .	./cache/cord-291400-o9skj94r.txt	./txt/cord-291400-o9skj94r.txt