id author title date pages extension mime words sentences flesch summary cache txt cord-000916-b22s00es Kelso, Joel K Economic analysis of pandemic influenza mitigation strategies for five pandemic severity categories 2013-03-08 .txt text/plain 9171 412 42 This study estimates the effectiveness and total cost (from a societal perspective, with a lifespan time horizon) of a comprehensive range of social distancing and antiviral drug strategies, under a range of pandemic severity categories. For severe pandemics of category 3 (CFR 0.75%) and greater, a strategy combining antiviral treatment and prophylaxis, extended school closure and community contact reduction resulted in the lowest total cost of any strategy, costing $1,584 per person at category 5. For severe pandemics of category 3 (CFR 0.75%) and greater, a strategy combining antiviral treatment and prophylaxis, extended school closure and community contact reduction resulted in the lowest total cost of any strategy, costing $1,584 per person at category 5. Keywords: Pandemic influenza, Economic analysis, Antiviral medication, Social distancing, Pandemic severity, Case fatality ratio Background While the H1N1 2009 virus spread world-wide and was classed as a pandemic, the severity of resulting symptoms, as quantified by morbidity and mortality rates, was lower than that which had previously occurred in many seasonal epidemics [1] [2] [3] . ./cache/cord-000916-b22s00es.txt ./txt/cord-000916-b22s00es.txt