id sid tid token lemma pos cord-015369-72cjogxz 1 1 key key JJ cord-015369-72cjogxz 1 2 : : : cord-015369-72cjogxz 1 3 cord-015369 cord-015369 NNS cord-015369-72cjogxz 1 4 - - HYPH cord-015369-72cjogxz 1 5 72cjogxz 72cjogxz CD cord-015369-72cjogxz 1 6 authors author NNS cord-015369-72cjogxz 1 7 : : : cord-015369-72cjogxz 2 1 nan nan NNP cord-015369-72cjogxz 2 2 title title NN cord-015369-72cjogxz 2 3 : : : cord-015369-72cjogxz 2 4 50th 50th JJ cord-015369-72cjogxz 2 5 Annual Annual NNP cord-015369-72cjogxz 2 6 Meeting Meeting NNP cord-015369-72cjogxz 2 7 of of IN cord-015369-72cjogxz 2 8 the the DT cord-015369-72cjogxz 2 9 Austrian Austrian NNP cord-015369-72cjogxz 2 10 Society Society NNP cord-015369-72cjogxz 2 11 of of IN cord-015369-72cjogxz 2 12 Surgery Surgery NNP cord-015369-72cjogxz 2 13 . . . cord-015369-72cjogxz 3 1 Vienna Vienna NNP cord-015369-72cjogxz 3 2 , , , cord-015369-72cjogxz 3 3 June June NNP cord-015369-72cjogxz 3 4 18–20 18–20 CD cord-015369-72cjogxz 3 5 , , , cord-015369-72cjogxz 3 6 2009 2009 CD cord-015369-72cjogxz 3 7 . . . cord-015369-72cjogxz 4 1 Guest Guest NNP cord-015369-72cjogxz 4 2 Editors editor NNS cord-015369-72cjogxz 4 3 : : : cord-015369-72cjogxz 4 4 Albert Albert NNP cord-015369-72cjogxz 4 5 Tuchmann Tuchmann NNP cord-015369-72cjogxz 4 6 , , , cord-015369-72cjogxz 4 7 Erhard Erhard NNP cord-015369-72cjogxz 4 8 Schwanzer Schwanzer NNP cord-015369-72cjogxz 4 9 , , , cord-015369-72cjogxz 4 10 Benedikt Benedikt NNP cord-015369-72cjogxz 4 11 Walzel Walzel NNP cord-015369-72cjogxz 4 12 date date NN cord-015369-72cjogxz 4 13 : : : cord-015369-72cjogxz 4 14 2009 2009 CD cord-015369-72cjogxz 4 15 journal journal NN cord-015369-72cjogxz 4 16 : : : cord-015369-72cjogxz 5 1 Eur Eur NNP cord-015369-72cjogxz 5 2 Surg Surg NNP cord-015369-72cjogxz 5 3 DOI DOI NNP cord-015369-72cjogxz 5 4 : : : cord-015369-72cjogxz 5 5 10.1007 10.1007 CD cord-015369-72cjogxz 5 6 / / SYM cord-015369-72cjogxz 5 7 s10353 s10353 CD cord-015369-72cjogxz 5 8 - - HYPH cord-015369-72cjogxz 5 9 009 009 CD cord-015369-72cjogxz 5 10 - - HYPH cord-015369-72cjogxz 5 11 0461 0461 CD cord-015369-72cjogxz 5 12 - - SYM cord-015369-72cjogxz 5 13 1 1 CD cord-015369-72cjogxz 5 14 sha sha NNP cord-015369-72cjogxz 5 15 : : : cord-015369-72cjogxz 5 16 183bb39d6b28c62580c1319067d1974e2b2e2bb7 183bb39d6b28c62580c1319067d1974e2b2e2bb7 CD cord-015369-72cjogxz 5 17 doc_id doc_id CD cord-015369-72cjogxz 5 18 : : : cord-015369-72cjogxz 5 19 15369 15369 CD cord-015369-72cjogxz 5 20 cord_uid cord_uid NNS cord-015369-72cjogxz 5 21 : : : cord-015369-72cjogxz 5 22 72cjogxz 72cjogxz UH cord-015369-72cjogxz 5 23 nan nan NNP cord-015369-72cjogxz 5 24 Die Die NNP cord-015369-72cjogxz 5 25 transinguinale transinguinale NN cord-015369-72cjogxz 5 26 präperitoneale präperitoneale NN cord-015369-72cjogxz 5 27 Hernioplastik Hernioplastik NNP cord-015369-72cjogxz 5 28 wurde wurde VBD cord-015369-72cjogxz 5 29 in in IN cord-015369-72cjogxz 5 30 ihren ihren NNP cord-015369-72cjogxz 5 31 Grundzügen Grundzügen NNP cord-015369-72cjogxz 5 32 bereits bereits NNPS cord-015369-72cjogxz 5 33 in in IN cord-015369-72cjogxz 5 34 den den NNP cord-015369-72cjogxz 5 35 1960er 1960er NN cord-015369-72cjogxz 5 36 Jahren Jahren NNP cord-015369-72cjogxz 5 37 beschrieben beschrieben NNP cord-015369-72cjogxz 5 38 . . . cord-015369-72cjogxz 6 1 I -PRON- PRP cord-015369-72cjogxz 6 2 m be VBP cord-015369-72cjogxz 6 3 deutschsprachigen deutschsprachigen NNP cord-015369-72cjogxz 6 4 Raum Raum NNP cord-015369-72cjogxz 6 5 erfuhr erfuhr NN cord-015369-72cjogxz 6 6 das das NNP cord-015369-72cjogxz 6 7 Verfahren Verfahren NNP cord-015369-72cjogxz 6 8 durch durch NNP cord-015369-72cjogxz 6 9 die die NN cord-015369-72cjogxz 7 1 Arbeiten Arbeiten NNP cord-015369-72cjogxz 7 2 von von NNP cord-015369-72cjogxz 7 3 Schumpelick Schumpelick NNP cord-015369-72cjogxz 7 4 eine eine NNP cord-015369-72cjogxz 7 5 gewisse gewisse NN cord-015369-72cjogxz 7 6 Bedeutung Bedeutung NNP cord-015369-72cjogxz 7 7 . . . cord-015369-72cjogxz 8 1 Pelissier Pelissier NNP cord-015369-72cjogxz 8 2 entwickelte entwickelte NNP cord-015369-72cjogxz 8 3 basierend basierend NN cord-015369-72cjogxz 8 4 auf auf NNP cord-015369-72cjogxz 8 5 diesen diesen NNP cord-015369-72cjogxz 8 6 Grundlagen Grundlagen NNP cord-015369-72cjogxz 8 7 einen einen NNP cord-015369-72cjogxz 8 8 Patch Patch NNP cord-015369-72cjogxz 8 9 , , , cord-015369-72cjogxz 8 10 welcher welcher NNP cord-015369-72cjogxz 8 11 mit mit NNP cord-015369-72cjogxz 8 12 einem einem NNP cord-015369-72cjogxz 8 13 Memory Memory NNP cord-015369-72cjogxz 8 14 - - HYPH cord-015369-72cjogxz 8 15 Ring Ring NNP cord-015369-72cjogxz 8 16 armiert armiert NN cord-015369-72cjogxz 9 1 wurde wurde NNP cord-015369-72cjogxz 9 2 und und NNP cord-015369-72cjogxz 9 3 alle alle NNP cord-015369-72cjogxz 9 4 3 3 CD cord-015369-72cjogxz 9 5 Hernienkompartimente Hernienkompartimente NNP cord-015369-72cjogxz 9 6 der der NNP cord-015369-72cjogxz 9 7 Leiste Leiste NNP cord-015369-72cjogxz 9 8 abdeckt abdeckt NNS cord-015369-72cjogxz 9 9 . . . cord-015369-72cjogxz 10 1 Basierend Basierend NNP cord-015369-72cjogxz 10 2 auf auf NNP cord-015369-72cjogxz 11 1 909 909 CD cord-015369-72cjogxz 11 2 durch durch NNP cord-015369-72cjogxz 11 3 die die VBP cord-015369-72cjogxz 11 4 Autoren Autoren NNP cord-015369-72cjogxz 11 5 seit seit NNP cord-015369-72cjogxz 11 6 Oktober Oktober NNP cord-015369-72cjogxz 11 7 2004 2004 CD cord-015369-72cjogxz 12 1 durchgeführten durchgeführten NNP cord-015369-72cjogxz 12 2 Hernienreparationen Hernienreparationen NNP cord-015369-72cjogxz 12 3 wurden wurden NNS cord-015369-72cjogxz 12 4 die die VBP cord-015369-72cjogxz 12 5 Daten Daten NNP cord-015369-72cjogxz 12 6 prospektiv prospektiv NNP cord-015369-72cjogxz 12 7 erfasst erfasst NNP cord-015369-72cjogxz 12 8 und und IN cord-015369-72cjogxz 12 9 unter unter NNP cord-015369-72cjogxz 12 10 anderem anderem NNP cord-015369-72cjogxz 12 11 die die VBP cord-015369-72cjogxz 13 1 Komplikationen Komplikationen NNP cord-015369-72cjogxz 13 2 und und IN cord-015369-72cjogxz 13 3 Rezidive Rezidive NNP cord-015369-72cjogxz 13 4 analysiert analysiert NN cord-015369-72cjogxz 13 5 . . . cord-015369-72cjogxz 14 1 Hinsichtlich Hinsichtlich NNP cord-015369-72cjogxz 14 2 der der NNP cord-015369-72cjogxz 14 3 intraoperativen intraoperativen NNP cord-015369-72cjogxz 15 1 Komplikationen Komplikationen NNP cord-015369-72cjogxz 15 2 ergaben ergaben NN cord-015369-72cjogxz 15 3 sich sich NNP cord-015369-72cjogxz 15 4 1,1 1,1 CD cord-015369-72cjogxz 15 5 % % NN cord-015369-72cjogxz 16 1 Probleme Probleme NNP cord-015369-72cjogxz 16 2 wie wie NNP cord-015369-72cjogxz 16 3 Blasenläsion Blasenläsion NNP cord-015369-72cjogxz 16 4 und und IN cord-015369-72cjogxz 16 5 Verletzung Verletzung NNP cord-015369-72cjogxz 16 6 der der NNP cord-015369-72cjogxz 16 7 epigastrischen epigastrischen NNP cord-015369-72cjogxz 16 8 Gefäße Gefäße NNP cord-015369-72cjogxz 16 9 . . . cord-015369-72cjogxz 17 1 Postoperative Postoperative NNP cord-015369-72cjogxz 17 2 Komplikationen Komplikationen NNP cord-015369-72cjogxz 17 3 wurden wurden VBD cord-015369-72cjogxz 17 4 in in IN cord-015369-72cjogxz 17 5 8 8 CD cord-015369-72cjogxz 17 6 Fällen Fällen NNP cord-015369-72cjogxz 17 7 ( ( -LRB- cord-015369-72cjogxz 17 8 0,88 0,88 CD cord-015369-72cjogxz 17 9 % % NN cord-015369-72cjogxz 17 10 ) ) -RRB- cord-015369-72cjogxz 17 11 beobachtet beobachtet NNP cord-015369-72cjogxz 17 12 . . . cord-015369-72cjogxz 18 1 Insgesamt Insgesamt NNP cord-015369-72cjogxz 18 2 wurden wurden VBD cord-015369-72cjogxz 18 3 12 12 CD cord-015369-72cjogxz 18 4 Rezidivhernien Rezidivhernien NNP cord-015369-72cjogxz 18 5 diagnostiziert diagnostiziert NNP cord-015369-72cjogxz 18 6 ( ( -LRB- cord-015369-72cjogxz 18 7 bis bis NNP cord-015369-72cjogxz 18 8 25 25 CD cord-015369-72cjogxz 18 9 Monate Monate NNP cord-015369-72cjogxz 18 10 nach nach NNP cord-015369-72cjogxz 18 11 Implantation Implantation NNP cord-015369-72cjogxz 18 12 ) ) -RRB- cord-015369-72cjogxz 18 13 , , , cord-015369-72cjogxz 18 14 wobei wobei NNP cord-015369-72cjogxz 18 15 die die VBP cord-015369-72cjogxz 19 1 Verteilung Verteilung NNP cord-015369-72cjogxz 19 2 der der NNP cord-015369-72cjogxz 19 3 Rezidive Rezidive NNP cord-015369-72cjogxz 19 4 uneinheitlich uneinheitlich NNP cord-015369-72cjogxz 19 5 ist ist NNP cord-015369-72cjogxz 19 6 . . . cord-015369-72cjogxz 20 1 Es Es NNP cord-015369-72cjogxz 20 2 besteht besteht NNP cord-015369-72cjogxz 20 3 bislang bislang NNP cord-015369-72cjogxz 20 4 kein kein NNP cord-015369-72cjogxz 20 5 signifikanter signifikanter NNP cord-015369-72cjogxz 21 1 Unterschied Unterschied NNP cord-015369-72cjogxz 21 2 zwischen zwischen NNP cord-015369-72cjogxz 21 3 Fixierung Fixierung NNP cord-015369-72cjogxz 21 4 mit mit NNP cord-015369-72cjogxz 21 5 resorbierbarem resorbierbarem NNP cord-015369-72cjogxz 21 6 oder oder NNP cord-015369-72cjogxz 21 7 nicht nicht NNP cord-015369-72cjogxz 21 8 resorbierbaren resorbierbaren NNP cord-015369-72cjogxz 21 9 Nahtmaterial Nahtmaterial NNP cord-015369-72cjogxz 21 10 . . . cord-015369-72cjogxz 22 1 Ungeschlitzte Ungeschlitzte NNP cord-015369-72cjogxz 22 2 Netze Netze NNP cord-015369-72cjogxz 22 3 zeigen zeigen XX cord-015369-72cjogxz 22 4 häufiger häufiger NNP cord-015369-72cjogxz 22 5 Rezidive Rezidive NNP cord-015369-72cjogxz 22 6 . . . cord-015369-72cjogxz 23 1 Die die VB cord-015369-72cjogxz 24 1 Beschaffenheit Beschaffenheit NNP cord-015369-72cjogxz 24 2 des des NNP cord-015369-72cjogxz 24 3 Patches Patches NNP cord-015369-72cjogxz 24 4 begü begü NNP cord-015369-72cjogxz 24 5 nstigt nstigt RB cord-015369-72cjogxz 25 1 i -PRON- PRP cord-015369-72cjogxz 25 2 m be VBP cord-015369-72cjogxz 25 3 Einzelfall Einzelfall NNP cord-015369-72cjogxz 25 4 wahrscheinlich wahrscheinlich NNP cord-015369-72cjogxz 25 5 die die VBP cord-015369-72cjogxz 25 6 Rezidiventstehung Rezidiventstehung NNP cord-015369-72cjogxz 25 7 . . . cord-015369-72cjogxz 26 1 2 2 LS cord-015369-72cjogxz 26 2 Netze Netze NNP cord-015369-72cjogxz 26 3 wurden wurden VBD cord-015369-72cjogxz 26 4 wegen wegen NNP cord-015369-72cjogxz 26 5 einer einer NNP cord-015369-72cjogxz 26 6 Schmerzsymptomatik Schmerzsymptomatik NNP cord-015369-72cjogxz 27 1 i i PRP cord-015369-72cjogxz 28 1 m m NNP cord-015369-72cjogxz 28 2 Bereich Bereich NNP cord-015369-72cjogxz 28 3 des des NNP cord-015369-72cjogxz 28 4 Schambeines Schambeines NNP cord-015369-72cjogxz 28 5 entfernt entfernt NNP cord-015369-72cjogxz 28 6 ( ( -LRB- cord-015369-72cjogxz 28 7 2 2 CD cord-015369-72cjogxz 28 8 - - SYM cord-015369-72cjogxz 28 9 4d 4d CD cord-015369-72cjogxz 28 10 post post NN cord-015369-72cjogxz 28 11 op op NN cord-015369-72cjogxz 28 12 ) ) -RRB- cord-015369-72cjogxz 28 13 , , . cord-015369-72cjogxz 29 1 1 1 CD cord-015369-72cjogxz 29 2 Netz Netz NNP cord-015369-72cjogxz 29 3 wegen wegen NNP cord-015369-72cjogxz 29 4 Schmerzen Schmerzen NNP cord-015369-72cjogxz 29 5 am be VBP cord-015369-72cjogxz 29 6 Netzoberrand Netzoberrand NNP cord-015369-72cjogxz 29 7 39 39 CD cord-015369-72cjogxz 29 8 m m NN cord-015369-72cjogxz 29 9 nach nach NNP cord-015369-72cjogxz 29 10 Implantation Implantation NNP cord-015369-72cjogxz 29 11 . . . cord-015369-72cjogxz 30 1 Bezü Bezü NNP cord-015369-72cjogxz 30 2 glich glich NNP cord-015369-72cjogxz 30 3 der der NNP cord-015369-72cjogxz 30 4 allgemeinen allgemeinen NNP cord-015369-72cjogxz 31 1 Komplikationen Komplikationen NNP cord-015369-72cjogxz 31 2 unterscheidet unterscheidet NNP cord-015369-72cjogxz 31 3 sich sich NNP cord-015369-72cjogxz 31 4 das das NNP cord-015369-72cjogxz 31 5 Verfahren Verfahren NNP cord-015369-72cjogxz 31 6 nicht nicht NNP cord-015369-72cjogxz 31 7 von von NNP cord-015369-72cjogxz 31 8 den den NNP cord-015369-72cjogxz 31 9 gängigen gängigen NNP cord-015369-72cjogxz 31 10 Hernienreparationen Hernienreparationen NNP cord-015369-72cjogxz 31 11 , , , cord-015369-72cjogxz 31 12 die die VB cord-015369-72cjogxz 31 13 Rezidivrate Rezidivrate NNP cord-015369-72cjogxz 31 14 ist ist FW cord-015369-72cjogxz 31 15 auch auch NNP cord-015369-72cjogxz 31 16 i -PRON- PRP cord-015369-72cjogxz 31 17 m be VBP cord-015369-72cjogxz 31 18 längeren längeren NNP cord-015369-72cjogxz 31 19 Beobachtungszeitraum Beobachtungszeitraum NNP cord-015369-72cjogxz 31 20 gering gering NNP cord-015369-72cjogxz 31 21 . . . cord-015369-72cjogxz 32 1 Es Es NNP cord-015369-72cjogxz 32 2 werden werden NNP cord-015369-72cjogxz 32 3 die die VBP cord-015369-72cjogxz 32 4 Problemzonen Problemzonen NNP cord-015369-72cjogxz 32 5 des des NNP cord-015369-72cjogxz 32 6 Patches Patches NNP cord-015369-72cjogxz 32 7 diskutiert diskutiert NNP cord-015369-72cjogxz 32 8 . . . cord-015369-72cjogxz 33 1 Klinisch Klinisch NNP cord-015369-72cjogxz 33 2 diagnostizierte diagnostizierte VBZ cord-015369-72cjogxz 33 3 Hernien Hernien NNP cord-015369-72cjogxz 33 4 ohne ohne NNP cord-015369-72cjogxz 33 5 peritoneale peritoneale NNP cord-015369-72cjogxz 33 6 Ausstülpung Ausstülpung NNP cord-015369-72cjogxz 33 7 C. C. NNP cord-015369-72cjogxz 33 8 Hollinsky Hollinsky NNP cord-015369-72cjogxz 33 9 , , , cord-015369-72cjogxz 33 10 S. S. NNP cord-015369-72cjogxz 33 11 Sandberg Sandberg NNP cord-015369-72cjogxz 33 12 KH KH NNP cord-015369-72cjogxz 33 13 Floridsdorf Floridsdorf NNP cord-015369-72cjogxz 33 14 , , , cord-015369-72cjogxz 33 15 Chirurgische Chirurgische NNP cord-015369-72cjogxz 33 16 Abteilung Abteilung NNP cord-015369-72cjogxz 33 17 , , , cord-015369-72cjogxz 33 18 Vienna Vienna NNP cord-015369-72cjogxz 33 19 , , , cord-015369-72cjogxz 33 20 Austria Austria NNP cord-015369-72cjogxz 33 21 Grundlagen Grundlagen NNP cord-015369-72cjogxz 33 22 . . . cord-015369-72cjogxz 34 1 Bei Bei NNP cord-015369-72cjogxz 34 2 der der NNP cord-015369-72cjogxz 35 1 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 35 2 transabdominalen transabdominalen NNP cord-015369-72cjogxz 35 3 präperitonealen präperitonealen NNP cord-015369-72cjogxz 35 4 Meshplastik Meshplastik NNP cord-015369-72cjogxz 35 5 ( ( -LRB- cord-015369-72cjogxz 35 6 TAPP TAPP NNP cord-015369-72cjogxz 35 7 ) ) -RRB- cord-015369-72cjogxz 36 1 kö kö NNP cord-015369-72cjogxz 36 2 nnen nnen NNP cord-015369-72cjogxz 36 3 Leistenoder Leistenoder NNP cord-015369-72cjogxz 36 4 Femoralhernien Femoralhernien NNP cord-015369-72cjogxz 36 5 hinter hinter NN cord-015369-72cjogxz 36 6 einem einem NNP cord-015369-72cjogxz 36 7 intakten intakten NNP cord-015369-72cjogxz 36 8 Peritoneum Peritoneum NNP cord-015369-72cjogxz 36 9 verborgen verborgen NNP cord-015369-72cjogxz 36 10 sein sein NNP cord-015369-72cjogxz 36 11 . . . cord-015369-72cjogxz 37 1 Methodik Methodik NNP cord-015369-72cjogxz 37 2 . . . cord-015369-72cjogxz 38 1 In in IN cord-015369-72cjogxz 38 2 einer einer FW cord-015369-72cjogxz 38 3 prospektiv prospektiv FW cord-015369-72cjogxz 38 4 kontrollierten kontrollierten FW cord-015369-72cjogxz 38 5 Studie Studie NNP cord-015369-72cjogxz 38 6 wurden wurden VBD cord-015369-72cjogxz 38 7 alle alle NNP cord-015369-72cjogxz 38 8 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 38 9 Hernienoperationen Hernienoperationen NNP cord-015369-72cjogxz 38 10 der der NNP cord-015369-72cjogxz 38 11 letzten letzten NNP cord-015369-72cjogxz 39 1 15 15 CD cord-015369-72cjogxz 39 2 Jahre Jahre NNP cord-015369-72cjogxz 39 3 analysiert analysiert NN cord-015369-72cjogxz 39 4 . . . cord-015369-72cjogxz 40 1 Präoperativ präoperativ NN cord-015369-72cjogxz 40 2 wurden wurden VBD cord-015369-72cjogxz 40 3 alle alle NNP cord-015369-72cjogxz 40 4 Hernien Hernien NNP cord-015369-72cjogxz 40 5 vom vom NNP cord-015369-72cjogxz 41 1 Operateur Operateur NNP cord-015369-72cjogxz 41 2 klinisch klinisch NNP cord-015369-72cjogxz 41 3 untersucht untersucht NNP cord-015369-72cjogxz 41 4 und und NNP cord-015369-72cjogxz 41 5 bei bei NNP cord-015369-72cjogxz 41 6 unklarem unklarem NNP cord-015369-72cjogxz 41 7 Befund Befund NNP cord-015369-72cjogxz 41 8 wurden wurden NNP cord-015369-72cjogxz 41 9 ergänzend ergänzend NN cord-015369-72cjogxz 41 10 Ultraschall Ultraschall NNP cord-015369-72cjogxz 41 11 sowie sowie VBD cord-015369-72cjogxz 41 12 in in IN cord-015369-72cjogxz 41 13 seltenen seltenen NNP cord-015369-72cjogxz 41 14 Fällen Fällen NNP cord-015369-72cjogxz 41 15 ein ein NNP cord-015369-72cjogxz 41 16 MRT MRT NNP cord-015369-72cjogxz 41 17 durchgeführt durchgeführt NN cord-015369-72cjogxz 41 18 . . . cord-015369-72cjogxz 42 1 Intraoperativ intraoperativ JJ cord-015369-72cjogxz 42 2 wurden wurden NNS cord-015369-72cjogxz 42 3 alle alle NNP cord-015369-72cjogxz 42 4 suspizierten suspizierten NNP cord-015369-72cjogxz 43 1 Hernien Hernien NNP cord-015369-72cjogxz 43 2 auf auf NNP cord-015369-72cjogxz 43 3 das das NNP cord-015369-72cjogxz 43 4 Vorliegen Vorliegen NNP cord-015369-72cjogxz 43 5 eines eines NNPS cord-015369-72cjogxz 44 1 peritonealen peritonealen NNP cord-015369-72cjogxz 44 2 Herniensacks Herniensacks NNP cord-015369-72cjogxz 44 3 untersucht untersucht NN cord-015369-72cjogxz 45 1 sowie sowie NNP cord-015369-72cjogxz 45 2 die die VBP cord-015369-72cjogxz 46 1 i -PRON- PRP cord-015369-72cjogxz 46 2 m be VBP cord-015369-72cjogxz 46 3 Präperitonealraum Präperitonealraum NNP cord-015369-72cjogxz 46 4 eingesehene eingesehene NN cord-015369-72cjogxz 47 1 Pathologie Pathologie NNP cord-015369-72cjogxz 47 2 dokumentiert dokumentiert NNP cord-015369-72cjogxz 47 3 . . . cord-015369-72cjogxz 48 1 In in IN cord-015369-72cjogxz 48 2 einer einer NNP cord-015369-72cjogxz 48 3 multivariaten multivariaten NNP cord-015369-72cjogxz 48 4 Regressionsanalyse Regressionsanalyse NNP cord-015369-72cjogxz 48 5 wurden wurden VBD cord-015369-72cjogxz 48 6 eventuelle eventuelle NNP cord-015369-72cjogxz 48 7 Risikofaktoren Risikofaktoren NNP cord-015369-72cjogxz 48 8 auf auf NNP cord-015369-72cjogxz 48 9 deren deren NNP cord-015369-72cjogxz 48 10 Zusammenhang Zusammenhang NNP cord-015369-72cjogxz 48 11 mit mit NNP cord-015369-72cjogxz 48 12 einer einer NNP cord-015369-72cjogxz 48 13 Hernie Hernie NNP cord-015369-72cjogxz 48 14 ohne ohne NNP cord-015369-72cjogxz 48 15 Peritonealdefekt Peritonealdefekt NNP cord-015369-72cjogxz 48 16 ermittelt ermittelt NNS cord-015369-72cjogxz 48 17 . . . cord-015369-72cjogxz 49 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 49 2 . . . cord-015369-72cjogxz 50 1 Bei Bei NNP cord-015369-72cjogxz 50 2 6,2 6,2 CD cord-015369-72cjogxz 50 3 % % NN cord-015369-72cjogxz 50 4 der der NN cord-015369-72cjogxz 50 5 Hernien Hernien NNP cord-015369-72cjogxz 50 6 war war NN cord-015369-72cjogxz 50 7 intraoperativ intraoperativ NNP cord-015369-72cjogxz 50 8 kein kein NNP cord-015369-72cjogxz 50 9 peritonealer peritonealer NNP cord-015369-72cjogxz 50 10 Herniensack Herniensack NNP cord-015369-72cjogxz 50 11 ersichtlich ersichtlich NNP cord-015369-72cjogxz 50 12 . . . cord-015369-72cjogxz 51 1 Dabei Dabei NNP cord-015369-72cjogxz 51 2 handelte handelte NNP cord-015369-72cjogxz 51 3 es es NNP cord-015369-72cjogxz 51 4 sich sich NNP cord-015369-72cjogxz 51 5 in in IN cord-015369-72cjogxz 51 6 erster erster NNP cord-015369-72cjogxz 51 7 Linie Linie NNP cord-015369-72cjogxz 51 8 um um UH cord-015369-72cjogxz 51 9 Femoralhernien Femoralhernien NNP cord-015369-72cjogxz 51 10 sowie sowie XX cord-015369-72cjogxz 52 1 durch durch NNP cord-015369-72cjogxz 52 2 präperitoneales präperitoneale NNS cord-015369-72cjogxz 52 3 Fett Fett NNP cord-015369-72cjogxz 52 4 ausgefüllte ausgefüllte FW cord-015369-72cjogxz 52 5 Inguinalhernien Inguinalhernien NNP cord-015369-72cjogxz 52 6 . . . cord-015369-72cjogxz 53 1 Bei Bei NNP cord-015369-72cjogxz 53 2 der der NNP cord-015369-72cjogxz 54 1 multivariaten multivariaten NNP cord-015369-72cjogxz 54 2 Regressionsanalyse Regressionsanalyse NNP cord-015369-72cjogxz 54 3 zeigte zeigte NNP cord-015369-72cjogxz 55 1 sich sich NNP cord-015369-72cjogxz 55 2 neben neben NNP cord-015369-72cjogxz 55 3 der der NNP cord-015369-72cjogxz 55 4 Femoralhernie Femoralhernie NNP cord-015369-72cjogxz 55 5 sowohl sowohl NN cord-015369-72cjogxz 55 6 die die VBP cord-015369-72cjogxz 56 1 Bruchpfortengröße Bruchpfortengröße NNP cord-015369-72cjogxz 56 2 als als NN cord-015369-72cjogxz 56 3 auch auch JJ cord-015369-72cjogxz 56 4 das das NNP cord-015369-72cjogxz 56 5 Alter alter VB cord-015369-72cjogxz 56 6 als als NN cord-015369-72cjogxz 56 7 signifikante signifikante NNP cord-015369-72cjogxz 56 8 Risikofaktoren Risikofaktoren NNP cord-015369-72cjogxz 56 9 für für IN cord-015369-72cjogxz 56 10 Hernien Hernien NNP cord-015369-72cjogxz 56 11 ohne ohne NNP cord-015369-72cjogxz 56 12 Peritonealbeteiligung Peritonealbeteiligung NNP cord-015369-72cjogxz 56 13 . . . cord-015369-72cjogxz 57 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 57 2 . . . cord-015369-72cjogxz 58 1 Aufgrund Aufgrund NNP cord-015369-72cjogxz 58 2 dieser dieser NNP cord-015369-72cjogxz 58 3 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 58 4 sollte sollte NNP cord-015369-72cjogxz 58 5 bei bei NNP cord-015369-72cjogxz 58 6 klinisch klinisch NNP cord-015369-72cjogxz 58 7 diagnostizierten diagnostizierten NNP cord-015369-72cjogxz 58 8 Hernien Hernien NNP cord-015369-72cjogxz 58 9 der der NNP cord-015369-72cjogxz 58 10 Inguinalregion Inguinalregion NNP cord-015369-72cjogxz 58 11 intraoperativ intraoperativ NNP cord-015369-72cjogxz 58 12 der der NNP cord-015369-72cjogxz 58 13 Präperitonealraum Präperitonealraum NNP cord-015369-72cjogxz 58 14 inspiziert inspiziert NNP cord-015369-72cjogxz 58 15 werden werden NNP cord-015369-72cjogxz 58 16 . . . cord-015369-72cjogxz 59 1 Feasibility feasibility NN cord-015369-72cjogxz 59 2 and and CC cord-015369-72cjogxz 59 3 potential potential JJ cord-015369-72cjogxz 59 4 advantages advantage NNS cord-015369-72cjogxz 59 5 of of IN cord-015369-72cjogxz 59 6 transporous transporous NNP cord-015369-72cjogxz 59 7 mesh mesh NN cord-015369-72cjogxz 59 8 fixation fixation NN cord-015369-72cjogxz 59 9 by by IN cord-015369-72cjogxz 59 10 a a DT cord-015369-72cjogxz 59 11 Laparoscopic Laparoscopic NNP cord-015369-72cjogxz 59 12 Spray Spray NNP cord-015369-72cjogxz 59 13 System system NN cord-015369-72cjogxz 59 14 ( ( -LRB- cord-015369-72cjogxz 59 15 LSS LSS NNP cord-015369-72cjogxz 59 16 ) ) -RRB- cord-015369-72cjogxz 59 17 in in IN cord-015369-72cjogxz 59 18 inguinal inguinal JJ cord-015369-72cjogxz 59 19 hernia hernia NN cord-015369-72cjogxz 59 20 repair repair NN cord-015369-72cjogxz 59 21 excellent excellent JJ cord-015369-72cjogxz 59 22 fixation fixation NN cord-015369-72cjogxz 59 23 accompanied accompany VBN cord-015369-72cjogxz 59 24 by by IN cord-015369-72cjogxz 59 25 a a DT cord-015369-72cjogxz 59 26 reduction reduction NN cord-015369-72cjogxz 59 27 of of IN cord-015369-72cjogxz 59 28 the the DT cord-015369-72cjogxz 59 29 amount amount NN cord-015369-72cjogxz 59 30 of of IN cord-015369-72cjogxz 59 31 FS fs NN cord-015369-72cjogxz 59 32 required require VBN cord-015369-72cjogxz 59 33 . . . cord-015369-72cjogxz 60 1 Investigation investigation NN cord-015369-72cjogxz 60 2 of of IN cord-015369-72cjogxz 60 3 a a DT cord-015369-72cjogxz 60 4 new new JJ cord-015369-72cjogxz 60 5 self self NN cord-015369-72cjogxz 60 6 - - HYPH cord-015369-72cjogxz 60 7 gripping grip VBG cord-015369-72cjogxz 60 8 mesh mesh NN cord-015369-72cjogxz 60 9 for for IN cord-015369-72cjogxz 60 10 hernia hernia NN cord-015369-72cjogxz 60 11 repair repair NN cord-015369-72cjogxz 60 12 in in IN cord-015369-72cjogxz 60 13 a a DT cord-015369-72cjogxz 60 14 rat rat NN cord-015369-72cjogxz 60 15 model model NN cord-015369-72cjogxz 61 1 In in IN cord-015369-72cjogxz 61 2 der der FW cord-015369-72cjogxz 61 3 modernen modernen NNP cord-015369-72cjogxz 61 4 Hernienchirurgie Hernienchirurgie NNP cord-015369-72cjogxz 61 5 verdrängen verdrängen NNP cord-015369-72cjogxz 61 6 Netzbasierte Netzbasierte NNP cord-015369-72cjogxz 61 7 Therapien Therapien NNP cord-015369-72cjogxz 61 8 zunehmend zunehmend MD cord-015369-72cjogxz 61 9 die die VB cord-015369-72cjogxz 61 10 klassischen klassischen NNP cord-015369-72cjogxz 61 11 Nahttechniken Nahttechniken NNP cord-015369-72cjogxz 61 12 . . . cord-015369-72cjogxz 62 1 In in IN cord-015369-72cjogxz 62 2 dieser dieser NNP cord-015369-72cjogxz 62 3 Untersuchung Untersuchung NNP cord-015369-72cjogxz 62 4 haben haben NNP cord-015369-72cjogxz 62 5 wir wir NNP cord-015369-72cjogxz 62 6 ein ein NNP cord-015369-72cjogxz 62 7 neues neues NNP cord-015369-72cjogxz 62 8 selbstfixierendes selbstfixierendes NNP cord-015369-72cjogxz 62 9 Netz Netz NNP cord-015369-72cjogxz 63 1 ( ( -LRB- cord-015369-72cjogxz 63 2 Parietene Parietene NNP cord-015369-72cjogxz 63 3 Progrip Progrip NNP cord-015369-72cjogxz 63 4 ) ) -RRB- cord-015369-72cjogxz 64 1 i -PRON- PRP cord-015369-72cjogxz 64 2 m be VBP cord-015369-72cjogxz 64 3 Tiermodell Tiermodell NNP cord-015369-72cjogxz 64 4 Ratte Ratte NNP cord-015369-72cjogxz 65 1 i -PRON- PRP cord-015369-72cjogxz 65 2 m be VBP cord-015369-72cjogxz 65 3 Vergleich Vergleich NNP cord-015369-72cjogxz 65 4 zu zu NNP cord-015369-72cjogxz 65 5 einem einem NNP cord-015369-72cjogxz 65 6 Standardnetz Standardnetz NNP cord-015369-72cjogxz 66 1 ( ( -LRB- cord-015369-72cjogxz 66 2 Parietene Parietene NNP cord-015369-72cjogxz 66 3 Light Light NNP cord-015369-72cjogxz 66 4 ) ) -RRB- cord-015369-72cjogxz 66 5 erprobt erprobt NN cord-015369-72cjogxz 66 6 . . . cord-015369-72cjogxz 67 1 Ziel Ziel NNP cord-015369-72cjogxz 67 2 war war NN cord-015369-72cjogxz 67 3 der der NN cord-015369-72cjogxz 67 4 Vergleich Vergleich NNP cord-015369-72cjogxz 67 5 der der NNP cord-015369-72cjogxz 67 6 Zugfestigkeit Zugfestigkeit NNP cord-015369-72cjogxz 67 7 5 5 CD cord-015369-72cjogxz 67 8 Tage Tage NNP cord-015369-72cjogxz 67 9 und und IN cord-015369-72cjogxz 67 10 2 2 CD cord-015369-72cjogxz 67 11 Monate Monate NNP cord-015369-72cjogxz 67 12 nach nach NNP cord-015369-72cjogxz 67 13 Aufbringen Aufbringen NNP cord-015369-72cjogxz 67 14 der der NNP cord-015369-72cjogxz 67 15 Netze Netze NNP cord-015369-72cjogxz 67 16 auf auf NNP cord-015369-72cjogxz 67 17 die die VBP cord-015369-72cjogxz 67 18 Bauchmuskulatur Bauchmuskulatur NNP cord-015369-72cjogxz 67 19 . . . cord-015369-72cjogxz 68 1 Die die VB cord-015369-72cjogxz 68 2 Fixierung Fixierung NNP cord-015369-72cjogxz 68 3 erfolgte erfolgte NN cord-015369-72cjogxz 68 4 bei bei NNP cord-015369-72cjogxz 68 5 dem dem NNP cord-015369-72cjogxz 68 6 Progrip Progrip NNP cord-015369-72cjogxz 68 7 - - HYPH cord-015369-72cjogxz 68 8 Netz Netz NNP cord-015369-72cjogxz 69 1 nur nur NNP cord-015369-72cjogxz 69 2 durch durch NNP cord-015369-72cjogxz 69 3 Mikrohaken Mikrohaken NNP cord-015369-72cjogxz 69 4 , , , cord-015369-72cjogxz 69 5 bei bei NNP cord-015369-72cjogxz 69 6 dem dem NNP cord-015369-72cjogxz 69 7 Parietene Parietene NNP cord-015369-72cjogxz 69 8 Light Light NNP cord-015369-72cjogxz 69 9 mittels mittels NNP cord-015369-72cjogxz 69 10 Titanklammern Titanklammern NNP cord-015369-72cjogxz 69 11 , , , cord-015369-72cjogxz 69 12 Gewebekleber Gewebekleber NNP cord-015369-72cjogxz 69 13 oder oder NN cord-015369-72cjogxz 69 14 ohne ohne NNP cord-015369-72cjogxz 69 15 Fixierung Fixierung NNP cord-015369-72cjogxz 69 16 . . . cord-015369-72cjogxz 70 1 I -PRON- PRP cord-015369-72cjogxz 70 2 m be VBP cord-015369-72cjogxz 70 3 Zugversuch Zugversuch NNP cord-015369-72cjogxz 70 4 wurde wurde NNP cord-015369-72cjogxz 70 5 die die VB cord-015369-72cjogxz 71 1 Scherfestigkeit Scherfestigkeit NNP cord-015369-72cjogxz 71 2 ermittelt ermittelt NNS cord-015369-72cjogxz 71 3 . . . cord-015369-72cjogxz 72 1 Außerdem Außerdem NNP cord-015369-72cjogxz 72 2 erfolgte erfolgte NNP cord-015369-72cjogxz 72 3 eine eine NNP cord-015369-72cjogxz 72 4 histologische histologische NN cord-015369-72cjogxz 73 1 Untersuchung Untersuchung NNP cord-015369-72cjogxz 73 2 auf auf NNP cord-015369-72cjogxz 73 3 entzü entzü NNS cord-015369-72cjogxz 73 4 ndliche ndliche NNP cord-015369-72cjogxz 73 5 Reaktionen Reaktionen NNP cord-015369-72cjogxz 73 6 sowie sowie NNP cord-015369-72cjogxz 73 7 eine eine NNP cord-015369-72cjogxz 73 8 elektronenmikroskopische elektronenmikroskopische NNP cord-015369-72cjogxz 74 1 Untersuchung Untersuchung NNP cord-015369-72cjogxz 74 2 auf auf NNP cord-015369-72cjogxz 74 3 Materialdegradation Materialdegradation NNP cord-015369-72cjogxz 74 4 . . . cord-015369-72cjogxz 75 1 Nach Nach NNP cord-015369-72cjogxz 75 2 5 5 CD cord-015369-72cjogxz 76 1 Tagen Tagen NNP cord-015369-72cjogxz 76 2 zeigten zeigten NNP cord-015369-72cjogxz 76 3 Progrip Progrip NNP cord-015369-72cjogxz 76 4 - - HYPH cord-015369-72cjogxz 76 5 und und NNP cord-015369-72cjogxz 76 6 Stapler Stapler NNP cord-015369-72cjogxz 76 7 - - HYPH cord-015369-72cjogxz 76 8 Fixierung Fixierung NNP cord-015369-72cjogxz 76 9 ähnlich ähnlich NNP cord-015369-72cjogxz 76 10 gute gute NNP cord-015369-72cjogxz 76 11 Zugfestigkeiten Zugfestigkeiten NNP cord-015369-72cjogxz 76 12 ( ( -LRB- cord-015369-72cjogxz 76 13 3,2 3,2 NNP cord-015369-72cjogxz 76 14 N N NNP cord-015369-72cjogxz 76 15 / / SYM cord-015369-72cjogxz 76 16 cm cm NNP cord-015369-72cjogxz 76 17 2 2 CD cord-015369-72cjogxz 76 18 ; ; : cord-015369-72cjogxz 76 19 2,7 2,7 CD cord-015369-72cjogxz 76 20 N n NN cord-015369-72cjogxz 76 21 / / SYM cord-015369-72cjogxz 76 22 cm cm NNP cord-015369-72cjogxz 76 23 2 2 CD cord-015369-72cjogxz 76 24 ) ) -RRB- cord-015369-72cjogxz 76 25 , , , cord-015369-72cjogxz 76 26 wohingegen wohingegen NNP cord-015369-72cjogxz 76 27 mit mit NNP cord-015369-72cjogxz 76 28 Gewebekleber Gewebekleber NNP cord-015369-72cjogxz 76 29 fixierte fixierte NN cord-015369-72cjogxz 76 30 Netze Netze NNP cord-015369-72cjogxz 76 31 genauso genauso NNP cord-015369-72cjogxz 77 1 wenig wenig NNP cord-015369-72cjogxz 77 2 Halt Halt NNP cord-015369-72cjogxz 77 3 hatten hatten NNP cord-015369-72cjogxz 78 1 wie wie NNP cord-015369-72cjogxz 78 2 unfixierte unfixierte NNP cord-015369-72cjogxz 78 3 Netze Netze NNP cord-015369-72cjogxz 78 4 ( ( -LRB- cord-015369-72cjogxz 78 5 0,9 0,9 CD cord-015369-72cjogxz 78 6 N n NN cord-015369-72cjogxz 78 7 / / SYM cord-015369-72cjogxz 78 8 cm cm NN cord-015369-72cjogxz 78 9 2 2 CD cord-015369-72cjogxz 78 10 ; ; : cord-015369-72cjogxz 78 11 1,5 1,5 CD cord-015369-72cjogxz 78 12 N n NN cord-015369-72cjogxz 78 13 / / SYM cord-015369-72cjogxz 78 14 cm cm NNP cord-015369-72cjogxz 78 15 2 2 CD cord-015369-72cjogxz 78 16 ; ; : cord-015369-72cjogxz 78 17 p p NN cord-015369-72cjogxz 78 18 < < XX cord-015369-72cjogxz 78 19 0,05 0,05 NNP cord-015369-72cjogxz 78 20 ) ) -RRB- cord-015369-72cjogxz 78 21 . . . cord-015369-72cjogxz 79 1 Nach Nach NNP cord-015369-72cjogxz 79 2 2 2 CD cord-015369-72cjogxz 79 3 Monaten Monaten NNP cord-015369-72cjogxz 79 4 waren waren NNP cord-015369-72cjogxz 79 5 die die VBP cord-015369-72cjogxz 80 1 Progrip Progrip NNP cord-015369-72cjogxz 80 2 - - HYPH cord-015369-72cjogxz 80 3 Netze Netze NNP cord-015369-72cjogxz 80 4 signifikant signifikant NN cord-015369-72cjogxz 80 5 besser besser NNP cord-015369-72cjogxz 80 6 auf auf NNP cord-015369-72cjogxz 80 7 dem dem NNP cord-015369-72cjogxz 80 8 Gewebe Gewebe NNP cord-015369-72cjogxz 80 9 fixiert fixiert NN cord-015369-72cjogxz 80 10 verglichen verglichen NNP cord-015369-72cjogxz 80 11 mit mit NNP cord-015369-72cjogxz 80 12 Stapler Stapler NNP cord-015369-72cjogxz 80 13 , , , cord-015369-72cjogxz 80 14 Kleber Kleber NNP cord-015369-72cjogxz 80 15 und und IN cord-015369-72cjogxz 80 16 ohne ohne NNP cord-015369-72cjogxz 80 17 Fixierung Fixierung NNP cord-015369-72cjogxz 81 1 ( ( -LRB- cord-015369-72cjogxz 81 2 14,8 14,8 CD cord-015369-72cjogxz 81 3 N N NNP cord-015369-72cjogxz 81 4 / / SYM cord-015369-72cjogxz 81 5 cm cm NN cord-015369-72cjogxz 81 6 2 2 CD cord-015369-72cjogxz 81 7 vs. vs. NN cord-015369-72cjogxz 81 8 11,7 11,7 CD cord-015369-72cjogxz 81 9 N n NN cord-015369-72cjogxz 81 10 / / SYM cord-015369-72cjogxz 81 11 cm cm NN cord-015369-72cjogxz 81 12 2 2 CD cord-015369-72cjogxz 81 13 ; ; . cord-015369-72cjogxz 82 1 11,4 11,4 CD cord-015369-72cjogxz 82 2 N n NN cord-015369-72cjogxz 82 3 / / SYM cord-015369-72cjogxz 82 4 cm cm NNP cord-015369-72cjogxz 83 1 2 2 CD cord-015369-72cjogxz 83 2 und und CD cord-015369-72cjogxz 83 3 8,7 8,7 CD cord-015369-72cjogxz 83 4 N n NN cord-015369-72cjogxz 83 5 / / SYM cord-015369-72cjogxz 83 6 cm cm NNP cord-015369-72cjogxz 83 7 2 2 CD cord-015369-72cjogxz 83 8 ; ; : cord-015369-72cjogxz 83 9 p p NN cord-015369-72cjogxz 83 10 < < XX cord-015369-72cjogxz 83 11 0,05 0,05 NNP cord-015369-72cjogxz 83 12 ) ) -RRB- cord-015369-72cjogxz 83 13 . . . cord-015369-72cjogxz 84 1 Die die VB cord-015369-72cjogxz 84 2 histologische histologische NN cord-015369-72cjogxz 85 1 Untersuchung Untersuchung NNP cord-015369-72cjogxz 85 2 zeigte zeigte NNP cord-015369-72cjogxz 85 3 nach nach NN cord-015369-72cjogxz 85 4 5 5 CD cord-015369-72cjogxz 85 5 Tagen Tagen NNP cord-015369-72cjogxz 86 1 entzündliche entzündliche NNP cord-015369-72cjogxz 86 2 Reaktionen Reaktionen NNP cord-015369-72cjogxz 86 3 i -PRON- PRP cord-015369-72cjogxz 86 4 m be VBP cord-015369-72cjogxz 86 5 Fremdkörperbereich Fremdkörperbereich NNP cord-015369-72cjogxz 86 6 bis bis NNP cord-015369-72cjogxz 86 7 in in IN cord-015369-72cjogxz 86 8 das das NNP cord-015369-72cjogxz 86 9 umgebende umgebende NNP cord-015369-72cjogxz 86 10 Bindegewebe Bindegewebe NNP cord-015369-72cjogxz 86 11 . . . cord-015369-72cjogxz 87 1 Nach Nach NNP cord-015369-72cjogxz 87 2 2 2 CD cord-015369-72cjogxz 88 1 Monaten Monaten NNP cord-015369-72cjogxz 88 2 ist ist NN cord-015369-72cjogxz 88 3 diese diese NNP cord-015369-72cjogxz 88 4 Gewebsreaktion Gewebsreaktion NNP cord-015369-72cjogxz 88 5 deutlich deutlich NNP cord-015369-72cjogxz 88 6 zurückgegangen zurückgegangen NNP cord-015369-72cjogxz 88 7 , , , cord-015369-72cjogxz 88 8 es es NNP cord-015369-72cjogxz 88 9 sind sind NNP cord-015369-72cjogxz 88 10 kaum kaum NNP cord-015369-72cjogxz 88 11 noch noch NNP cord-015369-72cjogxz 88 12 entzündliche entzündliche NNP cord-015369-72cjogxz 88 13 Zellen Zellen NNP cord-015369-72cjogxz 88 14 zu zu NNP cord-015369-72cjogxz 88 15 finden finden NNP cord-015369-72cjogxz 88 16 . . . cord-015369-72cjogxz 89 1 Stattdessen Stattdessen NNP cord-015369-72cjogxz 89 2 ist ist NN cord-015369-72cjogxz 89 3 das das NNP cord-015369-72cjogxz 89 4 Netzmaterial netzmaterial JJ cord-015369-72cjogxz 89 5 vermehrt vermehrt NN cord-015369-72cjogxz 89 6 von von NNP cord-015369-72cjogxz 89 7 Riesenzellen Riesenzellen NNP cord-015369-72cjogxz 89 8 umhüllt umhüllt NN cord-015369-72cjogxz 89 9 . . . cord-015369-72cjogxz 90 1 Die die VB cord-015369-72cjogxz 91 1 Progrip progrip NN cord-015369-72cjogxz 91 2 - - HYPH cord-015369-72cjogxz 91 3 Mikrohaken Mikrohaken NNP cord-015369-72cjogxz 91 4 reichen reichen NNP cord-015369-72cjogxz 91 5 deutlich deutlich NNP cord-015369-72cjogxz 91 6 in in IN cord-015369-72cjogxz 91 7 die die NNP cord-015369-72cjogxz 92 1 Muskulatur Muskulatur NNP cord-015369-72cjogxz 92 2 und und IN cord-015369-72cjogxz 92 3 sorgen sorgen NNP cord-015369-72cjogxz 92 4 dort dort NNP cord-015369-72cjogxz 92 5 für für NNP cord-015369-72cjogxz 92 6 eine eine NNP cord-015369-72cjogxz 92 7 gute gute NNP cord-015369-72cjogxz 92 8 Verankerung Verankerung NNP cord-015369-72cjogxz 92 9 . . . cord-015369-72cjogxz 93 1 Die die VB cord-015369-72cjogxz 93 2 elektronenmikroskopische elektronenmikroskopische NN cord-015369-72cjogxz 94 1 Untersuchung Untersuchung NNP cord-015369-72cjogxz 94 2 konnte konnte NNP cord-015369-72cjogxz 94 3 keinerlei keinerlei NNP cord-015369-72cjogxz 94 4 Materialveränderungen Materialveränderungen NNP cord-015369-72cjogxz 94 5 nach nach NNP cord-015369-72cjogxz 94 6 5 5 CD cord-015369-72cjogxz 94 7 Tagen Tagen NNP cord-015369-72cjogxz 94 8 oder oder NNP cord-015369-72cjogxz 95 1 2 2 LS cord-015369-72cjogxz 95 2 Monaten Monaten NNP cord-015369-72cjogxz 96 1 i i PRP cord-015369-72cjogxz 97 1 m m NNP cord-015369-72cjogxz 97 2 Vergleich Vergleich NNP cord-015369-72cjogxz 98 1 zu zu NNP cord-015369-72cjogxz 98 2 neuem neuem NNP cord-015369-72cjogxz 98 3 Netzmaterial Netzmaterial NNP cord-015369-72cjogxz 98 4 feststellen feststellen NNP cord-015369-72cjogxz 98 5 . . . cord-015369-72cjogxz 99 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 99 2 . . . cord-015369-72cjogxz 100 1 Das Das NNP cord-015369-72cjogxz 100 2 Progrip Progrip NNP cord-015369-72cjogxz 100 3 Netz Netz NNP cord-015369-72cjogxz 100 4 zeigte zeigte XX cord-015369-72cjogxz 101 1 eine eine NNP cord-015369-72cjogxz 101 2 deutlich deutlich NNP cord-015369-72cjogxz 101 3 bessere bessere NNP cord-015369-72cjogxz 102 1 Fixation fixation NN cord-015369-72cjogxz 102 2 i -PRON- PRP cord-015369-72cjogxz 102 3 m be VBP cord-015369-72cjogxz 102 4 Gewebe Gewebe NNP cord-015369-72cjogxz 102 5 als als NN cord-015369-72cjogxz 102 6 der der NN cord-015369-72cjogxz 102 7 Hernienstapler Hernienstapler NNP cord-015369-72cjogxz 103 1 oder oder NNP cord-015369-72cjogxz 103 2 der der NNP cord-015369-72cjogxz 103 3 Fibrinkleber Fibrinkleber NNP cord-015369-72cjogxz 103 4 und und IN cord-015369-72cjogxz 103 5 ist ist FW cord-015369-72cjogxz 103 6 zu zu NNP cord-015369-72cjogxz 103 7 diesen diesen NNP cord-015369-72cjogxz 103 8 Vergleichsfixationen Vergleichsfixationen NNP cord-015369-72cjogxz 103 9 eine eine NNP cord-015369-72cjogxz 103 10 kostengünstige kostengünstige NNP cord-015369-72cjogxz 103 11 Alternative Alternative NNP cord-015369-72cjogxz 103 12 . . . cord-015369-72cjogxz 104 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 104 2 . . . cord-015369-72cjogxz 105 1 Der Der NNP cord-015369-72cjogxz 105 2 Verschluss Verschluss NNP cord-015369-72cjogxz 105 3 von von NNP cord-015369-72cjogxz 105 4 Trokarinzisionen Trokarinzisionen NNP cord-015369-72cjogxz 105 5 ü ü NN cord-015369-72cjogxz 106 1 ber ber NNP cord-015369-72cjogxz 106 2 10 10 CD cord-015369-72cjogxz 106 3 mm mm NNP cord-015369-72cjogxz 106 4 wird wird NNP cord-015369-72cjogxz 106 5 empfohlen empfohlen NNP cord-015369-72cjogxz 106 6 aufgrund aufgrund NNP cord-015369-72cjogxz 106 7 des des NNP cord-015369-72cjogxz 106 8 Risikos Risikos NNP cord-015369-72cjogxz 106 9 einer einer NNP cord-015369-72cjogxz 106 10 Narbenhernienentstehung Narbenhernienentstehung NNP cord-015369-72cjogxz 106 11 . . . cord-015369-72cjogxz 107 1 Insbesondere Insbesondere NNP cord-015369-72cjogxz 107 2 bei bei NNP cord-015369-72cjogxz 107 3 adipösen adipösen NNP cord-015369-72cjogxz 108 1 Patienten Patienten NNP cord-015369-72cjogxz 108 2 ist ist NN cord-015369-72cjogxz 108 3 dieser dieser NNP cord-015369-72cjogxz 108 4 Verschluss Verschluss NNP cord-015369-72cjogxz 108 5 mit mit NNP cord-015369-72cjogxz 108 6 herkömmlichen herkömmlichen NNP cord-015369-72cjogxz 109 1 Methoden Methoden NNP cord-015369-72cjogxz 109 2 oft oft VBD cord-015369-72cjogxz 109 3 schwierig schwierig NNP cord-015369-72cjogxz 109 4 oder oder NN cord-015369-72cjogxz 109 5 nicht nicht NNP cord-015369-72cjogxz 109 6 durchfü durchfü NNP cord-015369-72cjogxz 109 7 hrbar hrbar NNP cord-015369-72cjogxz 109 8 . . . cord-015369-72cjogxz 110 1 In in IN cord-015369-72cjogxz 110 2 der der NN cord-015369-72cjogxz 110 3 Literatur Literatur NNP cord-015369-72cjogxz 110 4 finden finden NNP cord-015369-72cjogxz 110 5 sich sich NNP cord-015369-72cjogxz 111 1 Hinweise Hinweise NNP cord-015369-72cjogxz 111 2 auf auf NNP cord-015369-72cjogxz 111 3 eine eine NNP cord-015369-72cjogxz 111 4 deutlich deutlich NNP cord-015369-72cjogxz 111 5 erhöhte erhöhte NNP cord-015369-72cjogxz 111 6 Narbenhernieninzidenz Narbenhernieninzidenz NNP cord-015369-72cjogxz 111 7 i -PRON- PRP cord-015369-72cjogxz 111 8 m be VBP cord-015369-72cjogxz 112 1 Bereich Bereich NNP cord-015369-72cjogxz 112 2 von von NNP cord-015369-72cjogxz 112 3 Trokarstellen Trokarstellen NNP cord-015369-72cjogxz 112 4 nach nach NNP cord-015369-72cjogxz 112 5 laparoskopischer laparoskopischer NN cord-015369-72cjogxz 112 6 Narbenbruchoperation Narbenbruchoperation NNP cord-015369-72cjogxz 112 7 . . . cord-015369-72cjogxz 113 1 Methodik Methodik NNP cord-015369-72cjogxz 113 2 _SP cord-015369-72cjogxz 113 3 Klinik Klinik NNP cord-015369-72cjogxz 113 4 für für IN cord-015369-72cjogxz 113 5 Allgemein Allgemein NNP cord-015369-72cjogxz 113 6 - - HYPH cord-015369-72cjogxz 113 7 und und NNP cord-015369-72cjogxz 113 8 Visceralchirurgie Visceralchirurgie NNP cord-015369-72cjogxz 113 9 , , , cord-015369-72cjogxz 113 10 Bassum Bassum NNP cord-015369-72cjogxz 113 11 , , , cord-015369-72cjogxz 113 12 Germany Germany NNP cord-015369-72cjogxz 113 13 Grundlagen Grundlagen NNP cord-015369-72cjogxz 113 14 . . . cord-015369-72cjogxz 114 1 Sonographisch Sonographisch NNP cord-015369-72cjogxz 114 2 lassen lassen NNP cord-015369-72cjogxz 114 3 sich sich NNP cord-015369-72cjogxz 114 4 präzise präzise NNP cord-015369-72cjogxz 114 5 Befunde Befunde NNP cord-015369-72cjogxz 114 6 zur zur NNP cord-015369-72cjogxz 114 7 Pathologie Pathologie NNP cord-015369-72cjogxz 114 8 der der NNP cord-015369-72cjogxz 114 9 leiste leiste NNP cord-015369-72cjogxz 114 10 als als NNP cord-015369-72cjogxz 114 11 auch auch NNP cord-015369-72cjogxz 114 12 zur zur NNP cord-015369-72cjogxz 114 13 postoperativen postoperativen NNP cord-015369-72cjogxz 114 14 Situation Situation NNP cord-015369-72cjogxz 114 15 resp resp NNP cord-015369-72cjogxz 114 16 . . . cord-015369-72cjogxz 115 1 Komplikationen Komplikationen NNP cord-015369-72cjogxz 115 2 erheben erheben NNP cord-015369-72cjogxz 115 3 . . . cord-015369-72cjogxz 116 1 Fragestellung Fragestellung NNP cord-015369-72cjogxz 116 2 . . . cord-015369-72cjogxz 117 1 Bringt Bringt NNP cord-015369-72cjogxz 117 2 der der NNP cord-015369-72cjogxz 117 3 routinemäßige routinemäßige NNP cord-015369-72cjogxz 117 4 postoperative postoperative JJ cord-015369-72cjogxz 117 5 Einsatz Einsatz NNP cord-015369-72cjogxz 117 6 der der NNP cord-015369-72cjogxz 117 7 Sonographie Sonographie NNP cord-015369-72cjogxz 117 8 zusätzliche zusätzliche NN cord-015369-72cjogxz 117 9 relevante relevante NNP cord-015369-72cjogxz 117 10 Befunde Befunde NNP cord-015369-72cjogxz 117 11 zur zur NNP cord-015369-72cjogxz 117 12 Verlaufskontrolle Verlaufskontrolle NNP cord-015369-72cjogxz 117 13 ? ? . cord-015369-72cjogxz 118 1 Methodik Methodik NNP cord-015369-72cjogxz 118 2 . . . cord-015369-72cjogxz 119 1 600 600 CD cord-015369-72cjogxz 119 2 Leistenhernien Leistenhernien NNP cord-015369-72cjogxz 119 3 wurden wurden XX cord-015369-72cjogxz 120 1 nach nach NNP cord-015369-72cjogxz 120 2 transinguinaler transinguinaler NNP cord-015369-72cjogxz 120 3 präperitonealer präperitonealer NN cord-015369-72cjogxz 120 4 Hernioplastik Hernioplastik NNP cord-015369-72cjogxz 120 5 ( ( -LRB- cord-015369-72cjogxz 120 6 TIPP TIPP NNP cord-015369-72cjogxz 120 7 ) ) -RRB- cord-015369-72cjogxz 120 8 versorgt versorgt NNP cord-015369-72cjogxz 120 9 und und NNP cord-015369-72cjogxz 121 1 i -PRON- PRP cord-015369-72cjogxz 121 2 m be VBP cord-015369-72cjogxz 121 3 Rahmen Rahmen NNP cord-015369-72cjogxz 121 4 der der NNP cord-015369-72cjogxz 121 5 routinemäßigen routinemäßigen NNP cord-015369-72cjogxz 121 6 postoperativen postoperativen NNP cord-015369-72cjogxz 122 1 Kontrolle Kontrolle NNP cord-015369-72cjogxz 122 2 nach nach NNP cord-015369-72cjogxz 123 1 7 7 CD cord-015369-72cjogxz 123 2 - - SYM cord-015369-72cjogxz 123 3 15 15 CD cord-015369-72cjogxz 123 4 Tagen Tagen NNP cord-015369-72cjogxz 123 5 zusätzlich zusätzlich NNP cord-015369-72cjogxz 123 6 sonographisch sonographisch NNP cord-015369-72cjogxz 123 7 standardisiert standardisiert NNP cord-015369-72cjogxz 123 8 nach nach NNP cord-015369-72cjogxz 123 9 Netzlage Netzlage NNP cord-015369-72cjogxz 123 10 , , , cord-015369-72cjogxz 124 1 Hämatomen Hämatomen NNP cord-015369-72cjogxz 124 2 / / , cord-015369-72cjogxz 124 3 Seromen Seromen NNP cord-015369-72cjogxz 124 4 und und IN cord-015369-72cjogxz 124 5 Samenstrangdurchblutung Samenstrangdurchblutung NNP cord-015369-72cjogxz 124 6 untersucht untersucht NN cord-015369-72cjogxz 124 7 . . . cord-015369-72cjogxz 125 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 125 2 . . . cord-015369-72cjogxz 126 1 In in IN cord-015369-72cjogxz 126 2 allen allen NNP cord-015369-72cjogxz 126 3 Fällen Fällen NNP cord-015369-72cjogxz 126 4 fand fand VBP cord-015369-72cjogxz 126 5 sich sich NNP cord-015369-72cjogxz 126 6 eine eine FW cord-015369-72cjogxz 126 7 korrekte korrekte NNP cord-015369-72cjogxz 126 8 Netzlage Netzlage NNP cord-015369-72cjogxz 126 9 , , , cord-015369-72cjogxz 126 10 es es NNP cord-015369-72cjogxz 126 11 fand fand NNP cord-015369-72cjogxz 126 12 sich sich NNP cord-015369-72cjogxz 126 13 kein kein NNP cord-015369-72cjogxz 126 14 Rezidiv Rezidiv NNP cord-015369-72cjogxz 126 15 . . . cord-015369-72cjogxz 127 1 In in IN cord-015369-72cjogxz 127 2 43 43 CD cord-015369-72cjogxz 127 3 Fällen Fällen NNP cord-015369-72cjogxz 127 4 lag lag VBP cord-015369-72cjogxz 127 5 eine eine NNP cord-015369-72cjogxz 127 6 vermehrte vermehrte NNP cord-015369-72cjogxz 127 7 Netzwellung Netzwellung NNP cord-015369-72cjogxz 127 8 vor vor NNP cord-015369-72cjogxz 127 9 ( ( -LRB- cord-015369-72cjogxz 127 10 7,16 7,16 CD cord-015369-72cjogxz 127 11 % % NN cord-015369-72cjogxz 127 12 ) ) -RRB- cord-015369-72cjogxz 127 13 , , , cord-015369-72cjogxz 127 14 meist meist NNP cord-015369-72cjogxz 127 15 medial medial NN cord-015369-72cjogxz 127 16 , , , cord-015369-72cjogxz 128 1 selten selten NNP cord-015369-72cjogxz 128 2 lateral lateral NNP cord-015369-72cjogxz 128 3 . . . cord-015369-72cjogxz 129 1 In in IN cord-015369-72cjogxz 129 2 19/600 19/600 CD cord-015369-72cjogxz 129 3 Fällen Fällen NNP cord-015369-72cjogxz 129 4 ( ( -LRB- cord-015369-72cjogxz 129 5 3,1 3,1 CD cord-015369-72cjogxz 129 6 % % NN cord-015369-72cjogxz 129 7 ) ) -RRB- cord-015369-72cjogxz 130 1 fanden fanden NNP cord-015369-72cjogxz 130 2 sich sich NNP cord-015369-72cjogxz 130 3 Hämatome Hämatome NNP cord-015369-72cjogxz 130 4 / / SYM cord-015369-72cjogxz 130 5 Serome Serome NNP cord-015369-72cjogxz 131 1 > > XX cord-015369-72cjogxz 132 1 1 1 CD cord-015369-72cjogxz 132 2 cm cm NNP cord-015369-72cjogxz 132 3 Schichtdicke Schichtdicke NNP cord-015369-72cjogxz 132 4 , , , cord-015369-72cjogxz 132 5 deutlich deutlich NNP cord-015369-72cjogxz 132 6 häufiger häufiger NNP cord-015369-72cjogxz 132 7 > > XX cord-015369-72cjogxz 132 8 5 5 CD cord-015369-72cjogxz 132 9 mm mm NNP cord-015369-72cjogxz 132 10 ( ( -LRB- cord-015369-72cjogxz 132 11 94/600 94/600 CD cord-015369-72cjogxz 132 12 ) ) -RRB- cord-015369-72cjogxz 132 13 , , , cord-015369-72cjogxz 132 14 kleinere kleinere NNP cord-015369-72cjogxz 132 15 Hämatome Hämatome NNP cord-015369-72cjogxz 132 16 noch noch NNP cord-015369-72cjogxz 132 17 häufiger häufiger NNP cord-015369-72cjogxz 132 18 . . . cord-015369-72cjogxz 133 1 Keines Keines NNP cord-015369-72cjogxz 133 2 der der NNP cord-015369-72cjogxz 133 3 tiefen tiefen NN cord-015369-72cjogxz 134 1 Hämatome Hämatome NNP cord-015369-72cjogxz 134 2 musste musste NNP cord-015369-72cjogxz 135 1 revidiert revidiert NNP cord-015369-72cjogxz 136 1 /punktiert /punktiert NFP cord-015369-72cjogxz 136 2 werden werden NNP cord-015369-72cjogxz 136 3 , , , cord-015369-72cjogxz 136 4 2 2 CD cord-015369-72cjogxz 136 5 oberflächliche oberflächliche NN cord-015369-72cjogxz 136 6 Hämatome Hämatome NNP cord-015369-72cjogxz 136 7 wurden wurden VBD cord-015369-72cjogxz 136 8 revidiert revidiert NNP cord-015369-72cjogxz 136 9 , , , cord-015369-72cjogxz 137 1 19 19 CD cord-015369-72cjogxz 137 2 Patienten Patienten NNP cord-015369-72cjogxz 137 3 wurden wurden NNP cord-015369-72cjogxz 137 4 ein ein NNP cord-015369-72cjogxz 137 5 - - HYPH cord-015369-72cjogxz 137 6 oder oder NNP cord-015369-72cjogxz 137 7 mehrfach mehrfach NNP cord-015369-72cjogxz 137 8 punktiert punktiert NNP cord-015369-72cjogxz 137 9 . . . cord-015369-72cjogxz 138 1 4 4 CD cord-015369-72cjogxz 138 2 postoperative postoperative JJ cord-015369-72cjogxz 138 3 Hydrocelen Hydrocelen NNP cord-015369-72cjogxz 138 4 wurden wurden NNP cord-015369-72cjogxz 138 5 beobachtet beobachtet NNP cord-015369-72cjogxz 138 6 . . . cord-015369-72cjogxz 139 1 Die die VB cord-015369-72cjogxz 140 1 Durchblutung Durchblutung NNP cord-015369-72cjogxz 140 2 von von NNP cord-015369-72cjogxz 140 3 Samenstrang Samenstrang NNP cord-015369-72cjogxz 140 4 oder oder NNP cord-015369-72cjogxz 140 5 Hoden Hoden NNP cord-015369-72cjogxz 140 6 war war NN cord-015369-72cjogxz 140 7 sonographisch sonographisch NN cord-015369-72cjogxz 140 8 in in IN cord-015369-72cjogxz 140 9 allen allen NNP cord-015369-72cjogxz 140 10 Fällen Fällen NNP cord-015369-72cjogxz 140 11 intakt intakt NNS cord-015369-72cjogxz 140 12 . . . cord-015369-72cjogxz 141 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 141 2 . . . cord-015369-72cjogxz 142 1 Die die VB cord-015369-72cjogxz 142 2 routinemäßige routinemäßige NNP cord-015369-72cjogxz 143 1 Sonographie Sonographie NNP cord-015369-72cjogxz 143 2 - - HYPH cord-015369-72cjogxz 143 3 Kontrolle Kontrolle NNP cord-015369-72cjogxz 143 4 nach nach NNP cord-015369-72cjogxz 143 5 Leistenhernienoperation Leistenhernienoperation NNP cord-015369-72cjogxz 143 6 ( ( -LRB- cord-015369-72cjogxz 143 7 hier hier NNP cord-015369-72cjogxz 143 8 TIPP TIPP NNP cord-015369-72cjogxz 143 9 ) ) -RRB- cord-015369-72cjogxz 143 10 hat hat NN cord-015369-72cjogxz 143 11 nur nur NNP cord-015369-72cjogxz 143 12 gelegentlich gelegentlich NNP cord-015369-72cjogxz 143 13 therapeutische therapeutische IN cord-015369-72cjogxz 143 14 Konsequenzen Konsequenzen NNP cord-015369-72cjogxz 144 1 fast fast NNP cord-015369-72cjogxz 144 2 immer immer NNP cord-015369-72cjogxz 144 3 zusammen zusammen NNP cord-015369-72cjogxz 144 4 mit mit NNP cord-015369-72cjogxz 144 5 dem dem NNP cord-015369-72cjogxz 144 6 klinischen klinischen NNP cord-015369-72cjogxz 144 7 Befund Befund NNP cord-015369-72cjogxz 144 8 . . . cord-015369-72cjogxz 145 1 Aufgrund Aufgrund NNP cord-015369-72cjogxz 146 1 der der NNP cord-015369-72cjogxz 146 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 146 3 sollte sollte NNP cord-015369-72cjogxz 147 1 daher daher NNP cord-015369-72cjogxz 147 2 ein ein NNP cord-015369-72cjogxz 147 3 on on IN cord-015369-72cjogxz 147 4 - - HYPH cord-015369-72cjogxz 147 5 demand demand NN cord-015369-72cjogxz 147 6 - - HYPH cord-015369-72cjogxz 147 7 Vorgehen vorgehen NN cord-015369-72cjogxz 147 8 als als NNP cord-015369-72cjogxz 147 9 ausreichend ausreichend NNP cord-015369-72cjogxz 147 10 angesehen angesehen NNP cord-015369-72cjogxz 147 11 werden werden NNP cord-015369-72cjogxz 147 12 . . . cord-015369-72cjogxz 148 1 In in IN cord-015369-72cjogxz 148 2 Hinblick Hinblick NNP cord-015369-72cjogxz 148 3 auf auf NNP cord-015369-72cjogxz 148 4 die die VBP cord-015369-72cjogxz 149 1 Bestätigung Bestätigung NNP cord-015369-72cjogxz 149 2 des des NNP cord-015369-72cjogxz 150 1 frühen frühen NNP cord-015369-72cjogxz 151 1 postoperativen postoperativen NNP cord-015369-72cjogxz 152 1 Befundes Befundes NNP cord-015369-72cjogxz 152 2 wird wird JJ cord-015369-72cjogxz 153 1 die die VB cord-015369-72cjogxz 153 2 routinemäßige routinemäßige NNP cord-015369-72cjogxz 153 3 sonographische sonographische NNP cord-015369-72cjogxz 154 1 Kontrolle Kontrolle NNP cord-015369-72cjogxz 154 2 von von NNP cord-015369-72cjogxz 154 3 den den NNP cord-015369-72cjogxz 155 1 meisten meisten NNP cord-015369-72cjogxz 155 2 Patienten Patienten NNP cord-015369-72cjogxz 155 3 aber aber NNP cord-015369-72cjogxz 155 4 als als NN cord-015369-72cjogxz 155 5 positive positive JJ cord-015369-72cjogxz 155 6 Bestätigung Bestätigung NNP cord-015369-72cjogxz 155 7 angesehen angesehen NNP cord-015369-72cjogxz 155 8 . . . cord-015369-72cjogxz 156 1 Das Das NNP cord-015369-72cjogxz 156 2 Video Video NNP cord-015369-72cjogxz 156 3 zeigt zeigt NNP cord-015369-72cjogxz 156 4 eine eine NNP cord-015369-72cjogxz 156 5 neue neue NNP cord-015369-72cjogxz 156 6 onkoplastische onkoplastische NN cord-015369-72cjogxz 156 7 Technik Technik NNP cord-015369-72cjogxz 156 8 beim beim NNP cord-015369-72cjogxz 156 9 Mammakarzinom Mammakarzinom NNP cord-015369-72cjogxz 156 10 . . . cord-015369-72cjogxz 157 1 Die die VB cord-015369-72cjogxz 157 2 Tumorquadrantektomie Tumorquadrantektomie NNP cord-015369-72cjogxz 157 3 wird wird NNP cord-015369-72cjogxz 157 4 dabei dabei NNP cord-015369-72cjogxz 157 5 i -PRON- PRP cord-015369-72cjogxz 157 6 m be VBP cord-015369-72cjogxz 157 7 Rahmen Rahmen NNP cord-015369-72cjogxz 158 1 einer einer NNP cord-015369-72cjogxz 158 2 Reduktionsplastik Reduktionsplastik NNP cord-015369-72cjogxz 158 3 mit mit NNP cord-015369-72cjogxz 158 4 superior superior JJ cord-015369-72cjogxz 158 5 gestieltem gestieltem NNP cord-015369-72cjogxz 159 1 Pedikel Pedikel NNP cord-015369-72cjogxz 159 2 durchgefü durchgefü NN cord-015369-72cjogxz 159 3 hrt hrt NNP cord-015369-72cjogxz 159 4 . . . cord-015369-72cjogxz 160 1 Der Der NNP cord-015369-72cjogxz 160 2 inferiore inferiore NNP cord-015369-72cjogxz 160 3 Pedikel Pedikel NNP cord-015369-72cjogxz 160 4 , , , cord-015369-72cjogxz 160 5 der der NNP cord-015369-72cjogxz 160 6 normalerweise normalerweise NNP cord-015369-72cjogxz 160 7 reseziert reseziert NNP cord-015369-72cjogxz 160 8 wird wird NNP cord-015369-72cjogxz 160 9 , , , cord-015369-72cjogxz 160 10 wird wird NNP cord-015369-72cjogxz 160 11 dabei dabei NNP cord-015369-72cjogxz 160 12 zur zur NNP cord-015369-72cjogxz 160 13 Defekdeckung Defekdeckung NNP cord-015369-72cjogxz 160 14 genutzt genutzt NNP cord-015369-72cjogxz 160 15 . . . cord-015369-72cjogxz 161 1 Ist Ist NNP cord-015369-72cjogxz 162 1 eine eine NNP cord-015369-72cjogxz 162 2 Resektion Resektion NNP cord-015369-72cjogxz 162 3 des des FW cord-015369-72cjogxz 162 4 Tumors Tumors NNP cord-015369-72cjogxz 163 1 mit mit NNP cord-015369-72cjogxz 163 2 darü darü NNP cord-015369-72cjogxz 163 3 berliegender berliegender NNP cord-015369-72cjogxz 163 4 Haut Haut NNP cord-015369-72cjogxz 163 5 nötig nötig FW cord-015369-72cjogxz 163 6 wird wird NNP cord-015369-72cjogxz 163 7 der der NNP cord-015369-72cjogxz 163 8 inferiore inferiore FW cord-015369-72cjogxz 163 9 Pedikel Pedikel NNP cord-015369-72cjogxz 163 10 nicht nicht FW cord-015369-72cjogxz 163 11 komplett komplett NNP cord-015369-72cjogxz 163 12 de de NNP cord-015369-72cjogxz 163 13 - - HYPH cord-015369-72cjogxz 163 14 epithelisiert epithelisiert NNP cord-015369-72cjogxz 163 15 , , , cord-015369-72cjogxz 163 16 sondern sondern NNP cord-015369-72cjogxz 163 17 mit mit NNP cord-015369-72cjogxz 163 18 Hautinsel Hautinsel NNP cord-015369-72cjogxz 163 19 in in IN cord-015369-72cjogxz 163 20 den den NNP cord-015369-72cjogxz 163 21 Defekt Defekt NNP cord-015369-72cjogxz 163 22 eingeschwenkt eingeschwenkt NNS cord-015369-72cjogxz 163 23 . . . cord-015369-72cjogxz 164 1 Die die VB cord-015369-72cjogxz 164 2 Technik Technik NNP cord-015369-72cjogxz 164 3 erlaubt erlaubt NNP cord-015369-72cjogxz 164 4 Rekonstruktion Rekonstruktion NNP cord-015369-72cjogxz 164 5 auch auch NNP cord-015369-72cjogxz 164 6 von von NNP cord-015369-72cjogxz 164 7 kleinen kleinen NNP cord-015369-72cjogxz 165 1 und und NNP cord-015369-72cjogxz 166 1 mittelgroßen mittelgroßen NNP cord-015369-72cjogxz 166 2 Brü Brü NNP cord-015369-72cjogxz 166 3 sten sten NNP cord-015369-72cjogxz 167 1 , , , cord-015369-72cjogxz 167 2 sowie sowie NNP cord-015369-72cjogxz 167 3 von von NNP cord-015369-72cjogxz 167 4 Defekten Defekten NNP cord-015369-72cjogxz 167 5 i -PRON- PRP cord-015369-72cjogxz 167 6 m be VBP cord-015369-72cjogxz 167 7 inneren inneren NNP cord-015369-72cjogxz 168 1 Quadrant Quadrant NNP cord-015369-72cjogxz 168 2 der der NNP cord-015369-72cjogxz 168 3 kontralateralen kontralateralen NNP cord-015369-72cjogxz 168 4 Brust Brust NNP cord-015369-72cjogxz 168 5 . . . cord-015369-72cjogxz 169 1 Oncoplastic oncoplastic JJ cord-015369-72cjogxz 169 2 surgery surgery NN cord-015369-72cjogxz 169 3 : : : cord-015369-72cjogxz 169 4 The the DT cord-015369-72cjogxz 169 5 use use NN cord-015369-72cjogxz 169 6 of of IN cord-015369-72cjogxz 169 7 a a DT cord-015369-72cjogxz 169 8 breast breast NN cord-015369-72cjogxz 169 9 reduction reduction NN cord-015369-72cjogxz 169 10 to to TO cord-015369-72cjogxz 169 11 improve improve VB cord-015369-72cjogxz 169 12 cosmetic cosmetic JJ cord-015369-72cjogxz 169 13 outcome outcome NN cord-015369-72cjogxz 169 14 for for IN cord-015369-72cjogxz 169 15 breast breast NN cord-015369-72cjogxz 169 16 conserving conserve VBG cord-015369-72cjogxz 169 17 surgery surgery NN cord-015369-72cjogxz 170 1 ( ( -LRB- cord-015369-72cjogxz 170 2 VIDEO video NN cord-015369-72cjogxz 170 3 ) ) -RRB- cord-015369-72cjogxz 171 1 Oncoplastic oncoplastic JJ cord-015369-72cjogxz 171 2 techniques technique NNS cord-015369-72cjogxz 171 3 have have VBP cord-015369-72cjogxz 171 4 increasingly increasingly RB cord-015369-72cjogxz 171 5 been be VBN cord-015369-72cjogxz 171 6 used use VBN cord-015369-72cjogxz 171 7 in in IN cord-015369-72cjogxz 171 8 the the DT cord-015369-72cjogxz 171 9 last last JJ cord-015369-72cjogxz 171 10 20 20 CD cord-015369-72cjogxz 171 11 years year NNS cord-015369-72cjogxz 171 12 in in IN cord-015369-72cjogxz 171 13 Europe Europe NNP cord-015369-72cjogxz 171 14 and and CC cord-015369-72cjogxz 171 15 the the DT cord-015369-72cjogxz 171 16 United United NNP cord-015369-72cjogxz 171 17 States States NNP cord-015369-72cjogxz 171 18 . . . cord-015369-72cjogxz 172 1 Several several JJ cord-015369-72cjogxz 172 2 techniques technique NNS cord-015369-72cjogxz 172 3 have have VBP cord-015369-72cjogxz 172 4 been be VBN cord-015369-72cjogxz 172 5 described describe VBN cord-015369-72cjogxz 172 6 . . . cord-015369-72cjogxz 173 1 Beside beside IN cord-015369-72cjogxz 173 2 the the DT cord-015369-72cjogxz 173 3 use use NN cord-015369-72cjogxz 173 4 of of IN cord-015369-72cjogxz 173 5 local local JJ cord-015369-72cjogxz 173 6 and and CC cord-015369-72cjogxz 173 7 free free JJ cord-015369-72cjogxz 173 8 flaps flap NNS cord-015369-72cjogxz 173 9 after after IN cord-015369-72cjogxz 173 10 mastectomy mastectomy NN cord-015369-72cjogxz 173 11 the the DT cord-015369-72cjogxz 173 12 use use NN cord-015369-72cjogxz 173 13 of of IN cord-015369-72cjogxz 173 14 breast breast NN cord-015369-72cjogxz 173 15 reduction reduction NN cord-015369-72cjogxz 173 16 techniques technique NNS cord-015369-72cjogxz 173 17 solved solve VBD cord-015369-72cjogxz 173 18 several several JJ cord-015369-72cjogxz 173 19 problems problem NNS cord-015369-72cjogxz 173 20 for for IN cord-015369-72cjogxz 173 21 breast breast NN cord-015369-72cjogxz 173 22 conserving conserve VBG cord-015369-72cjogxz 173 23 surgery surgery NN cord-015369-72cjogxz 173 24 . . . cord-015369-72cjogxz 174 1 This this DT cord-015369-72cjogxz 174 2 video video NN cord-015369-72cjogxz 174 3 demonstrates demonstrate VBZ cord-015369-72cjogxz 174 4 one one CD cord-015369-72cjogxz 174 5 possible possible JJ cord-015369-72cjogxz 174 6 technique technique NN cord-015369-72cjogxz 174 7 to to TO cord-015369-72cjogxz 174 8 improve improve VB cord-015369-72cjogxz 174 9 breast breast NN cord-015369-72cjogxz 174 10 symmetry symmetry NN cord-015369-72cjogxz 174 11 during during IN cord-015369-72cjogxz 174 12 breast breast NN cord-015369-72cjogxz 174 13 conserving conserve VBG cord-015369-72cjogxz 174 14 surgery surgery NN cord-015369-72cjogxz 174 15 . . . cord-015369-72cjogxz 175 1 Skin skin NN cord-015369-72cjogxz 175 2 - - HYPH cord-015369-72cjogxz 175 3 sparing spare VBG cord-015369-72cjogxz 175 4 mastektomy mastektomy NN cord-015369-72cjogxz 175 5 and and CC cord-015369-72cjogxz 175 6 immediate immediate JJ cord-015369-72cjogxz 175 7 reconstruction reconstruction NN cord-015369-72cjogxz 175 8 of of IN cord-015369-72cjogxz 175 9 the the DT cord-015369-72cjogxz 175 10 breasta breasta NNP cord-015369-72cjogxz 175 11 videopresentation videopresentation NNP cord-015369-72cjogxz 175 12 Grundlagen Grundlagen NNP cord-015369-72cjogxz 175 13 . . . cord-015369-72cjogxz 176 1 Die die VB cord-015369-72cjogxz 176 2 Erhaltung Erhaltung NNP cord-015369-72cjogxz 176 3 der der NNP cord-015369-72cjogxz 176 4 Kosmesis Kosmesis NNP cord-015369-72cjogxz 177 1 i i PRP cord-015369-72cjogxz 178 1 m m NNP cord-015369-72cjogxz 178 2 Rahmen Rahmen NNP cord-015369-72cjogxz 178 3 der der NNP cord-015369-72cjogxz 178 4 chirurgischen chirurgischen NNP cord-015369-72cjogxz 178 5 Therapie Therapie NNP cord-015369-72cjogxz 178 6 des des FW cord-015369-72cjogxz 178 7 Mammakarzinomes Mammakarzinomes NNP cord-015369-72cjogxz 178 8 ist ist NN cord-015369-72cjogxz 178 9 von von NNP cord-015369-72cjogxz 178 10 zentraler zentraler NNP cord-015369-72cjogxz 178 11 Bedeutung Bedeutung NNP cord-015369-72cjogxz 178 12 . . . cord-015369-72cjogxz 179 1 Trotz Trotz NNP cord-015369-72cjogxz 179 2 der der NNP cord-015369-72cjogxz 179 3 vielfachen vielfachen NNP cord-015369-72cjogxz 180 1 Möglichkeit Möglichkeit NNP cord-015369-72cjogxz 180 2 einer einer NNP cord-015369-72cjogxz 180 3 brusterhaltenden brusterhaltenden JJ cord-015369-72cjogxz 180 4 Therapie Therapie NNP cord-015369-72cjogxz 180 5 , , , cord-015369-72cjogxz 180 6 zwingen zwingen NNP cord-015369-72cjogxz 180 7 spezielle spezielle NNP cord-015369-72cjogxz 180 8 Indikationen Indikationen NNP cord-015369-72cjogxz 180 9 auch auch NNP cord-015369-72cjogxz 180 10 heutzutage heutzutage NN cord-015369-72cjogxz 180 11 noch noch NNP cord-015369-72cjogxz 180 12 zu zu NNP cord-015369-72cjogxz 180 13 einer einer NNP cord-015369-72cjogxz 180 14 kompletten kompletten NNP cord-015369-72cjogxz 180 15 Entfernung Entfernung NNP cord-015369-72cjogxz 180 16 des des NNP cord-015369-72cjogxz 180 17 Brustdrü Brustdrü NNP cord-015369-72cjogxz 180 18 dengewebes dengewebes NNP cord-015369-72cjogxz 180 19 . . . cord-015369-72cjogxz 181 1 Dabei Dabei NNP cord-015369-72cjogxz 181 2 kommen kommen NNP cord-015369-72cjogxz 182 1 immer immer NNP cord-015369-72cjogxz 183 1 häufiger häufiger NNP cord-015369-72cjogxz 183 2 hautsparende hautsparende NNP cord-015369-72cjogxz 184 1 Techniken Techniken NNP cord-015369-72cjogxz 184 2 bis bis NN cord-015369-72cjogxz 184 3 hin hin NN cord-015369-72cjogxz 184 4 zur zur NNP cord-015369-72cjogxz 184 5 Erhaltung Erhaltung NNP cord-015369-72cjogxz 184 6 der der NNP cord-015369-72cjogxz 184 7 Areola Areola NNP cord-015369-72cjogxz 184 8 oder oder NNP cord-015369-72cjogxz 184 9 sogar sogar NNP cord-015369-72cjogxz 184 10 der der NNP cord-015369-72cjogxz 184 11 Mamille Mamille NNP cord-015369-72cjogxz 184 12 zur zur NNP cord-015369-72cjogxz 184 13 Anwendung Anwendung NNP cord-015369-72cjogxz 184 14 . . . cord-015369-72cjogxz 185 1 I -PRON- PRP cord-015369-72cjogxz 185 2 m be VBP cord-015369-72cjogxz 185 3 Rahmen Rahmen NNP cord-015369-72cjogxz 185 4 einer einer NNP cord-015369-72cjogxz 185 5 Videopräsentation Videopräsentation NNP cord-015369-72cjogxz 185 6 soll soll NNP cord-015369-72cjogxz 185 7 die die VB cord-015369-72cjogxz 186 1 Technik Technik NNP cord-015369-72cjogxz 186 2 der der NN cord-015369-72cjogxz 186 3 Skin skin NN cord-015369-72cjogxz 186 4 - - HYPH cord-015369-72cjogxz 186 5 Sparing sparing NN cord-015369-72cjogxz 186 6 Mastektomie Mastektomie NNP cord-015369-72cjogxz 187 1 und und NNP cord-015369-72cjogxz 187 2 Sofortrekonstruktion Sofortrekonstruktion NNP cord-015369-72cjogxz 187 3 der der NNP cord-015369-72cjogxz 187 4 Brust Brust NNP cord-015369-72cjogxz 187 5 veranschaulicht veranschaulicht NN cord-015369-72cjogxz 188 1 werden werden NNP cord-015369-72cjogxz 188 2 . . . cord-015369-72cjogxz 189 1 Methodik Methodik NNP cord-015369-72cjogxz 189 2 . . . cord-015369-72cjogxz 190 1 Von Von NNP cord-015369-72cjogxz 190 2 345 345 CD cord-015369-72cjogxz 190 3 Patientinnen Patientinnen NNP cord-015369-72cjogxz 190 4 , , , cord-015369-72cjogxz 190 5 die die VB cord-015369-72cjogxz 190 6 seit seit NNP cord-015369-72cjogxz 190 7 Mai Mai NNP cord-015369-72cjogxz 190 8 2000 2000 CD cord-015369-72cjogxz 191 1 an an DT cord-015369-72cjogxz 191 2 unserer unserer JJ cord-015369-72cjogxz 191 3 Abteilung Abteilung NNP cord-015369-72cjogxz 191 4 eine eine NNP cord-015369-72cjogxz 191 5 Brustrekonstruktion Brustrekonstruktion NNP cord-015369-72cjogxz 191 6 erhielten erhielten NN cord-015369-72cjogxz 191 7 , , , cord-015369-72cjogxz 191 8 konnten konnten NNP cord-015369-72cjogxz 191 9 in in IN cord-015369-72cjogxz 191 10 38 38 CD cord-015369-72cjogxz 191 11 Fällen Fällen NNP cord-015369-72cjogxz 191 12 hautsparende hautsparende NNP cord-015369-72cjogxz 191 13 Techniken Techniken NNP cord-015369-72cjogxz 191 14 angewendet angewendet NNP cord-015369-72cjogxz 191 15 werden werden NNP cord-015369-72cjogxz 191 16 . . . cord-015369-72cjogxz 192 1 Zur Zur NNP cord-015369-72cjogxz 192 2 Präsentation Präsentation NNP cord-015369-72cjogxz 192 3 der der NN cord-015369-72cjogxz 192 4 Technik Technik NNP cord-015369-72cjogxz 192 5 der der NN cord-015369-72cjogxz 192 6 Skin skin NN cord-015369-72cjogxz 192 7 - - HYPH cord-015369-72cjogxz 192 8 sparing spare VBG cord-015369-72cjogxz 192 9 Mastektomie Mastektomie NNP cord-015369-72cjogxz 192 10 mit mit NNP cord-015369-72cjogxz 192 11 Sofortrekonstruktion Sofortrekonstruktion NNP cord-015369-72cjogxz 192 12 der der NNP cord-015369-72cjogxz 192 13 Brust Brust NNP cord-015369-72cjogxz 192 14 wurde wurde NNP cord-015369-72cjogxz 192 15 ein ein NNP cord-015369-72cjogxz 192 16 Operationsvideo Operationsvideo NNP cord-015369-72cjogxz 192 17 angefertigt angefertigt NNP cord-015369-72cjogxz 192 18 . . . cord-015369-72cjogxz 193 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 193 2 . . . cord-015369-72cjogxz 194 1 Die die VBP cord-015369-72cjogxz 194 2 i -PRON- PRP cord-015369-72cjogxz 194 3 m be VBP cord-015369-72cjogxz 194 4 Video video NN cord-015369-72cjogxz 194 5 präsentierte präsentierte NN cord-015369-72cjogxz 195 1 Technik Technik NNP cord-015369-72cjogxz 195 2 führt führt NNP cord-015369-72cjogxz 195 3 zu zu NNP cord-015369-72cjogxz 196 1 einem einem NNP cord-015369-72cjogxz 196 2 kosmetisch kosmetisch NNP cord-015369-72cjogxz 197 1 ansprechenden ansprechenden NNP cord-015369-72cjogxz 197 2 Ergebnis Ergebnis NNP cord-015369-72cjogxz 198 1 für für NNP cord-015369-72cjogxz 198 2 die die VBP cord-015369-72cjogxz 198 3 Patientin Patientin NNP cord-015369-72cjogxz 198 4 . . . cord-015369-72cjogxz 199 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 199 2 . . . cord-015369-72cjogxz 200 1 Um um UH cord-015369-72cjogxz 200 2 fü fü IN cord-015369-72cjogxz 200 3 r r NN cord-015369-72cjogxz 200 4 die die VB cord-015369-72cjogxz 201 1 Patientinnen Patientinnen NNP cord-015369-72cjogxz 201 2 optimale optimale NNP cord-015369-72cjogxz 202 1 postoperative postoperative JJ cord-015369-72cjogxz 202 2 Resultate Resultate NNP cord-015369-72cjogxz 202 3 erreichen erreichen NNP cord-015369-72cjogxz 202 4 zu zu NNP cord-015369-72cjogxz 202 5 können können XX cord-015369-72cjogxz 203 1 , , , cord-015369-72cjogxz 203 2 sollte sollte NNP cord-015369-72cjogxz 203 3 die die NNP cord-015369-72cjogxz 203 4 vorgestellte vorgestellte NNP cord-015369-72cjogxz 203 5 Technik Technik NNP cord-015369-72cjogxz 203 6 einen einen NNP cord-015369-72cjogxz 203 7 integralen integralen NNP cord-015369-72cjogxz 204 1 Bestandteil Bestandteil NNP cord-015369-72cjogxz 204 2 des des NNP cord-015369-72cjogxz 204 3 Therapiekonzeptes Therapiekonzeptes NNPS cord-015369-72cjogxz 204 4 des des FW cord-015369-72cjogxz 204 5 Mammakarzinoms Mammakarzinoms NNP cord-015369-72cjogxz 204 6 darstellen darstellen NNS cord-015369-72cjogxz 204 7 und und IN cord-015369-72cjogxz 204 8 den den NNP cord-015369-72cjogxz 204 9 Patientinnen Patientinnen NNP cord-015369-72cjogxz 204 10 schon schon NNP cord-015369-72cjogxz 204 11 nach nach NN cord-015369-72cjogxz 204 12 der der NNP cord-015369-72cjogxz 204 13 Diagnosestellung Diagnosestellung NNP cord-015369-72cjogxz 204 14 offeriert offeriert NNP cord-015369-72cjogxz 204 15 werden werden NNP cord-015369-72cjogxz 204 16 . . . cord-015369-72cjogxz 205 1 The the DT cord-015369-72cjogxz 205 2 treatment treatment NN cord-015369-72cjogxz 205 3 of of IN cord-015369-72cjogxz 205 4 nonhealing nonheale VBG cord-015369-72cjogxz 205 5 and and CC cord-015369-72cjogxz 205 6 infected infected JJ cord-015369-72cjogxz 205 7 sternotomies sternotomie NNS cord-015369-72cjogxz 205 8 following follow VBG cord-015369-72cjogxz 205 9 cardiac cardiac JJ cord-015369-72cjogxz 205 10 surgery surgery NN cord-015369-72cjogxz 205 11 is be VBZ cord-015369-72cjogxz 205 12 a a DT cord-015369-72cjogxz 205 13 challenging challenging JJ cord-015369-72cjogxz 205 14 task task NN cord-015369-72cjogxz 205 15 , , , cord-015369-72cjogxz 205 16 with with IN cord-015369-72cjogxz 205 17 increased increase VBN cord-015369-72cjogxz 205 18 rates rate NNS cord-015369-72cjogxz 205 19 of of IN cord-015369-72cjogxz 205 20 mortality mortality NN cord-015369-72cjogxz 205 21 and and CC cord-015369-72cjogxz 205 22 morbidity morbidity NN cord-015369-72cjogxz 205 23 , , , cord-015369-72cjogxz 205 24 as as RB cord-015369-72cjogxz 205 25 well well RB cord-015369-72cjogxz 205 26 as as IN cord-015369-72cjogxz 205 27 high high JJ cord-015369-72cjogxz 205 28 costs cost NNS cord-015369-72cjogxz 205 29 . . . cord-015369-72cjogxz 206 1 Local local JJ cord-015369-72cjogxz 206 2 vacuum vacuum NN cord-015369-72cjogxz 206 3 therapy therapy NN cord-015369-72cjogxz 206 4 ( ( -LRB- cord-015369-72cjogxz 206 5 V.A.C. V.A.C. NNP cord-015369-72cjogxz 206 6 system system NN cord-015369-72cjogxz 206 7 ) ) -RRB- cord-015369-72cjogxz 206 8 permits permit VBZ cord-015369-72cjogxz 206 9 the the DT cord-015369-72cjogxz 206 10 treatment treatment NN cord-015369-72cjogxz 206 11 of of IN cord-015369-72cjogxz 206 12 deep deep JJ cord-015369-72cjogxz 206 13 sternal sternal JJ cord-015369-72cjogxz 206 14 infections infection NNS cord-015369-72cjogxz 206 15 due due JJ cord-015369-72cjogxz 206 16 to to IN cord-015369-72cjogxz 206 17 continuous continuous JJ cord-015369-72cjogxz 206 18 aspiration aspiration NN cord-015369-72cjogxz 206 19 and and CC cord-015369-72cjogxz 206 20 a a DT cord-015369-72cjogxz 206 21 sealed seal VBN cord-015369-72cjogxz 206 22 dressing dressing NN cord-015369-72cjogxz 206 23 which which WDT cord-015369-72cjogxz 206 24 stimulates stimulate VBZ cord-015369-72cjogxz 206 25 granulation granulation NN cord-015369-72cjogxz 206 26 tissue tissue NN cord-015369-72cjogxz 206 27 formation formation NN cord-015369-72cjogxz 206 28 . . . cord-015369-72cjogxz 207 1 Aggressive aggressive JJ cord-015369-72cjogxz 207 2 vacuum vacuum NN cord-015369-72cjogxz 207 3 - - HYPH cord-015369-72cjogxz 207 4 assisted assist VBN cord-015369-72cjogxz 207 5 closure closure NN cord-015369-72cjogxz 207 6 treatment treatment NN cord-015369-72cjogxz 207 7 of of IN cord-015369-72cjogxz 207 8 the the DT cord-015369-72cjogxz 207 9 sternum sternum NN cord-015369-72cjogxz 207 10 in in IN cord-015369-72cjogxz 207 11 postoperative postoperative JJ cord-015369-72cjogxz 207 12 deep deep JJ cord-015369-72cjogxz 207 13 wound wound NN cord-015369-72cjogxz 207 14 infection infection NN cord-015369-72cjogxz 207 15 enhances enhance VBZ cord-015369-72cjogxz 207 16 sternal sternal JJ cord-015369-72cjogxz 207 17 preservation preservation NN cord-015369-72cjogxz 207 18 and and CC cord-015369-72cjogxz 207 19 the the DT cord-015369-72cjogxz 207 20 speed speed NN cord-015369-72cjogxz 207 21 of of IN cord-015369-72cjogxz 207 22 potential potential JJ cord-015369-72cjogxz 207 23 rewiring rewiring NN cord-015369-72cjogxz 207 24 . . . cord-015369-72cjogxz 208 1 After after IN cord-015369-72cjogxz 208 2 some some DT cord-015369-72cjogxz 208 3 weeks week NNS cord-015369-72cjogxz 208 4 of of IN cord-015369-72cjogxz 208 5 V.A.C.-therapy V.A.C.-therapy NNP cord-015369-72cjogxz 208 6 a a DT cord-015369-72cjogxz 208 7 complete complete JJ cord-015369-72cjogxz 208 8 preparation preparation NN cord-015369-72cjogxz 208 9 of of IN cord-015369-72cjogxz 208 10 the the DT cord-015369-72cjogxz 208 11 substernal substernal JJ cord-015369-72cjogxz 208 12 structures structure NNS cord-015369-72cjogxz 208 13 is be VBZ cord-015369-72cjogxz 208 14 necessary necessary JJ cord-015369-72cjogxz 208 15 . . . cord-015369-72cjogxz 209 1 In in IN cord-015369-72cjogxz 209 2 this this DT cord-015369-72cjogxz 209 3 context context NN cord-015369-72cjogxz 209 4 laceration laceration NN cord-015369-72cjogxz 209 5 of of IN cord-015369-72cjogxz 209 6 the the DT cord-015369-72cjogxz 209 7 right right JJ cord-015369-72cjogxz 209 8 ventricle ventricle NN cord-015369-72cjogxz 209 9 is be VBZ cord-015369-72cjogxz 209 10 a a DT cord-015369-72cjogxz 209 11 rare rare JJ cord-015369-72cjogxz 209 12 , , , cord-015369-72cjogxz 209 13 but but CC cord-015369-72cjogxz 209 14 lifethreatening lifethreatening JJ cord-015369-72cjogxz 209 15 complication complication NN cord-015369-72cjogxz 209 16 . . . cord-015369-72cjogxz 210 1 We -PRON- PRP cord-015369-72cjogxz 210 2 describe describe VBP cord-015369-72cjogxz 210 3 a a DT cord-015369-72cjogxz 210 4 new new JJ cord-015369-72cjogxz 210 5 technique technique NN cord-015369-72cjogxz 210 6 for for IN cord-015369-72cjogxz 210 7 sternal sternal JJ cord-015369-72cjogxz 210 8 closure closure NN cord-015369-72cjogxz 210 9 after after IN cord-015369-72cjogxz 210 10 vacuum vacuum NN cord-015369-72cjogxz 210 11 - - HYPH cord-015369-72cjogxz 210 12 assisted assist VBN cord-015369-72cjogxz 210 13 wound wound NN cord-015369-72cjogxz 210 14 treatment treatment NN cord-015369-72cjogxz 210 15 using use VBG cord-015369-72cjogxz 210 16 Nitinol Nitinol NNP cord-015369-72cjogxz 210 17 clips clip NNS cord-015369-72cjogxz 210 18 which which WDT cord-015369-72cjogxz 210 19 can can MD cord-015369-72cjogxz 210 20 prevent prevent VB cord-015369-72cjogxz 210 21 these these DT cord-015369-72cjogxz 210 22 severe severe JJ cord-015369-72cjogxz 210 23 complications complication NNS cord-015369-72cjogxz 210 24 . . . cord-015369-72cjogxz 211 1 Without without IN cord-015369-72cjogxz 211 2 any any DT cord-015369-72cjogxz 211 3 preparation preparation NN cord-015369-72cjogxz 211 4 of of IN cord-015369-72cjogxz 211 5 the the DT cord-015369-72cjogxz 211 6 substernal substernal JJ cord-015369-72cjogxz 211 7 tissue tissue NN cord-015369-72cjogxz 211 8 the the DT cord-015369-72cjogxz 211 9 clips clip NNS cord-015369-72cjogxz 211 10 can can MD cord-015369-72cjogxz 211 11 be be VB cord-015369-72cjogxz 211 12 inserted insert VBN cord-015369-72cjogxz 211 13 in in IN cord-015369-72cjogxz 211 14 the the DT cord-015369-72cjogxz 211 15 parasternal parasternal JJ cord-015369-72cjogxz 211 16 space space NN cord-015369-72cjogxz 211 17 with with IN cord-015369-72cjogxz 211 18 consecutive consecutive JJ cord-015369-72cjogxz 211 19 proper proper JJ cord-015369-72cjogxz 211 20 stabilization stabilization NN cord-015369-72cjogxz 211 21 of of IN cord-015369-72cjogxz 211 22 the the DT cord-015369-72cjogxz 211 23 sternum sternum NN cord-015369-72cjogxz 211 24 . . . cord-015369-72cjogxz 212 1 This this DT cord-015369-72cjogxz 212 2 new new JJ cord-015369-72cjogxz 212 3 method method NN cord-015369-72cjogxz 212 4 represents represent VBZ cord-015369-72cjogxz 212 5 an an DT cord-015369-72cjogxz 212 6 easy easy JJ cord-015369-72cjogxz 212 7 , , , cord-015369-72cjogxz 212 8 low low JJ cord-015369-72cjogxz 212 9 - - HYPH cord-015369-72cjogxz 212 10 cost cost NN cord-015369-72cjogxz 212 11 and and CC cord-015369-72cjogxz 212 12 complication complication NN cord-015369-72cjogxz 212 13 - - HYPH cord-015369-72cjogxz 212 14 free free JJ cord-015369-72cjogxz 212 15 procedure procedure NN cord-015369-72cjogxz 212 16 . . . cord-015369-72cjogxz 213 1 Der Der NNP cord-015369-72cjogxz 213 2 gelegentlich gelegentlich NNP cord-015369-72cjogxz 213 3 oder oder NNP cord-015369-72cjogxz 213 4 ungelegentlich ungelegentlich NNP cord-015369-72cjogxz 213 5 angemahnte angemahnte NNP cord-015369-72cjogxz 213 6 , , , cord-015369-72cjogxz 213 7 , , , cord-015369-72cjogxz 213 8 Hippokratischer Hippokratischer NNP cord-015369-72cjogxz 213 9 Eid Eid NNP cord-015369-72cjogxz 213 10 ' ' '' cord-015369-72cjogxz 213 11 ' ' '' cord-015369-72cjogxz 213 12 ist ist FW cord-015369-72cjogxz 213 13 kaum kaum NNP cord-015369-72cjogxz 213 14 Wegweiser Wegweiser NNP cord-015369-72cjogxz 213 15 für für NNP cord-015369-72cjogxz 213 16 Chirurgie Chirurgie NNP cord-015369-72cjogxz 213 17 , , , cord-015369-72cjogxz 213 18 keineswegs keinesweg VBZ cord-015369-72cjogxz 213 19 weltweite weltweite NNP cord-015369-72cjogxz 213 20 Norm Norm NNP cord-015369-72cjogxz 213 21 , , , cord-015369-72cjogxz 213 22 Operationen Operationen NNP cord-015369-72cjogxz 213 23 werden werden NNP cord-015369-72cjogxz 213 24 ausdrücklich ausdrücklich VBD cord-015369-72cjogxz 213 25 verboten verboten NNP cord-015369-72cjogxz 213 26 . . . cord-015369-72cjogxz 214 1 Chirurgie Chirurgie NNP cord-015369-72cjogxz 214 2 muss muss NNP cord-015369-72cjogxz 214 3 also also RB cord-015369-72cjogxz 214 4 auf auf NNP cord-015369-72cjogxz 214 5 die die VB cord-015369-72cjogxz 215 1 praktische praktische NNP cord-015369-72cjogxz 215 2 Ethik Ethik NNP cord-015369-72cjogxz 215 3 zurückgreifen zurückgreifen NNP cord-015369-72cjogxz 215 4 und und NNP cord-015369-72cjogxz 215 5 daraus daraus NNP cord-015369-72cjogxz 215 6 gültige gültige NNP cord-015369-72cjogxz 215 7 moralische moralische NNP cord-015369-72cjogxz 215 8 und und NNP cord-015369-72cjogxz 215 9 wissenschaftliche wissenschaftliche NNP cord-015369-72cjogxz 215 10 ( ( -LRB- cord-015369-72cjogxz 215 11 Cochrane Cochrane NNP cord-015369-72cjogxz 215 12 ; ; : cord-015369-72cjogxz 215 13 1972 1972 CD cord-015369-72cjogxz 215 14 ) ) -RRB- cord-015369-72cjogxz 216 1 Prinzipien Prinzipien NNP cord-015369-72cjogxz 216 2 ableiten ableiten NNP cord-015369-72cjogxz 216 3 . . . cord-015369-72cjogxz 217 1 Diese Diese NNP cord-015369-72cjogxz 217 2 Prinzipien Prinzipien NNP cord-015369-72cjogxz 217 3 beruhen beruhen NNP cord-015369-72cjogxz 217 4 heute heute NNP cord-015369-72cjogxz 217 5 auf auf NNP cord-015369-72cjogxz 217 6 partnerschaftliche partnerschaftliche NNP cord-015369-72cjogxz 217 7 Arzt Arzt NNP cord-015369-72cjogxz 217 8 - - HYPH cord-015369-72cjogxz 217 9 Patient Patient NNP cord-015369-72cjogxz 217 10 - - HYPH cord-015369-72cjogxz 217 11 Beziehung Beziehung NNP cord-015369-72cjogxz 217 12 , , , cord-015369-72cjogxz 217 13 Schadensvermeidung Schadensvermeidung NNP cord-015369-72cjogxz 217 14 , , , cord-015369-72cjogxz 217 15 dem dem NNP cord-015369-72cjogxz 217 16 Bewusstsein Bewusstsein NNP cord-015369-72cjogxz 217 17 und und IN cord-015369-72cjogxz 217 18 der der NN cord-015369-72cjogxz 217 19 daraus daraus NN cord-015369-72cjogxz 217 20 folgenden folgenden NNP cord-015369-72cjogxz 217 21 Demut Demut NNP cord-015369-72cjogxz 217 22 , , , cord-015369-72cjogxz 217 23 dass dass NNP cord-015369-72cjogxz 217 24 der der NNP cord-015369-72cjogxz 217 25 Eingriff Eingriff NNP cord-015369-72cjogxz 217 26 als als NN cord-015369-72cjogxz 217 27 schwere schwere NN cord-015369-72cjogxz 217 28 Körperverletzung Körperverletzung NNP cord-015369-72cjogxz 217 29 , , , cord-015369-72cjogxz 217 30 unter unter NNP cord-015369-72cjogxz 217 31 dem dem NNP cord-015369-72cjogxz 217 32 Aspekt Aspekt NNP cord-015369-72cjogxz 217 33 der der NN cord-015369-72cjogxz 217 34 möglichen möglichen NNP cord-015369-72cjogxz 217 35 Heilung Heilung NNP cord-015369-72cjogxz 217 36 , , , cord-015369-72cjogxz 217 37 durchgeführt durchgeführt NNP cord-015369-72cjogxz 217 38 wird wird NNP cord-015369-72cjogxz 217 39 und und XX cord-015369-72cjogxz 218 1 Gerechtigkeit Gerechtigkeit NNP cord-015369-72cjogxz 218 2 -Handeln -handeln NN cord-015369-72cjogxz 218 3 ohne ohne NNP cord-015369-72cjogxz 218 4 Ansehen Ansehen NNP cord-015369-72cjogxz 218 5 der der NNP cord-015369-72cjogxz 218 6 Person Person NNP cord-015369-72cjogxz 218 7 . . . cord-015369-72cjogxz 219 1 Darauf Darauf NNP cord-015369-72cjogxz 219 2 basierend basierend NNP cord-015369-72cjogxz 219 3 wird wird NNP cord-015369-72cjogxz 219 4 in in IN cord-015369-72cjogxz 219 5 der der NNP cord-015369-72cjogxz 219 6 Neuzeit Neuzeit NNP cord-015369-72cjogxz 219 7 gelehrt gelehrt NN cord-015369-72cjogxz 219 8 . . . cord-015369-72cjogxz 220 1 Dies die VBZ cord-015369-72cjogxz 220 2 sollte sollte NNP cord-015369-72cjogxz 220 3 auch auch NNP cord-015369-72cjogxz 221 1 mitverantwortlichen mitverantwortlichen NNP cord-015369-72cjogxz 221 2 Spitalsökonomen Spitalsökonomen NNP cord-015369-72cjogxz 221 3 vermittelt vermittelt NNP cord-015369-72cjogxz 221 4 werden werden NNP cord-015369-72cjogxz 221 5 . . . cord-015369-72cjogxz 222 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 222 2 . . . cord-015369-72cjogxz 223 1 Immer Immer NNP cord-015369-72cjogxz 223 2 wieder wieder NNP cord-015369-72cjogxz 223 3 ist ist NNP cord-015369-72cjogxz 223 4 man man NN cord-015369-72cjogxz 223 5 in in IN cord-015369-72cjogxz 223 6 der der NNP cord-015369-72cjogxz 223 7 ärztlichen ärztlichen NNP cord-015369-72cjogxz 223 8 Tätigkeit Tätigkeit NNP cord-015369-72cjogxz 223 9 mit mit NN cord-015369-72cjogxz 223 10 den den NNP cord-015369-72cjogxz 223 11 Begriffen Begriffen NNP cord-015369-72cjogxz 223 12 Offlabel Offlabel NNP cord-015369-72cjogxz 223 13 , , , cord-015369-72cjogxz 223 14 Offlicence Offlicence NNP cord-015369-72cjogxz 223 15 , , , cord-015369-72cjogxz 223 16 Compassionate compassionate JJ cord-015369-72cjogxz 223 17 use use NN cord-015369-72cjogxz 223 18 , , , cord-015369-72cjogxz 223 19 Orphan Orphan NNP cord-015369-72cjogxz 223 20 Drug Drug NNP cord-015369-72cjogxz 223 21 , , , cord-015369-72cjogxz 223 22 individueller individueller NN cord-015369-72cjogxz 223 23 Heilversuch Heilversuch NNP cord-015369-72cjogxz 223 24 und und XX cord-015369-72cjogxz 224 1 experimentelle experimentelle NNP cord-015369-72cjogxz 224 2 Behandlung Behandlung NNP cord-015369-72cjogxz 224 3 konfrontiert konfrontiert NNP cord-015369-72cjogxz 224 4 . . . cord-015369-72cjogxz 225 1 Leider Leider NNP cord-015369-72cjogxz 225 2 gibt gibt NNP cord-015369-72cjogxz 225 3 es es NNP cord-015369-72cjogxz 226 1 für für NNP cord-015369-72cjogxz 226 2 die die VBP cord-015369-72cjogxz 226 3 wenigsten wenigsten NNP cord-015369-72cjogxz 226 4 dieser dieser NNP cord-015369-72cjogxz 227 1 Begriffe Begriffe NNP cord-015369-72cjogxz 227 2 gesetzliche gesetzliche NN cord-015369-72cjogxz 227 3 Definitionen Definitionen NNP cord-015369-72cjogxz 228 1 i -PRON- PRP cord-015369-72cjogxz 228 2 m be VBP cord-015369-72cjogxz 228 3 österreichischen österreichischen NNP cord-015369-72cjogxz 228 4 Recht Recht NNP cord-015369-72cjogxz 228 5 , , , cord-015369-72cjogxz 228 6 sie sie NNP cord-015369-72cjogxz 228 7 werden werden NNP cord-015369-72cjogxz 228 8 deshalb deshalb NNP cord-015369-72cjogxz 229 1 oft oft RB cord-015369-72cjogxz 229 2 widersprüchlich widersprüchlich WDT cord-015369-72cjogxz 229 3 und und IN cord-015369-72cjogxz 229 4 manchmal manchmal NNP cord-015369-72cjogxz 229 5 falsch falsch JJ cord-015369-72cjogxz 229 6 verwendet verwendet NNP cord-015369-72cjogxz 229 7 . . . cord-015369-72cjogxz 230 1 Ziel Ziel NNP cord-015369-72cjogxz 230 2 dieser dieser NNP cord-015369-72cjogxz 230 3 Arbeit Arbeit NNP cord-015369-72cjogxz 230 4 ist ist NN cord-015369-72cjogxz 230 5 es es XX cord-015369-72cjogxz 230 6 diese diese NNP cord-015369-72cjogxz 230 7 Begriffe Begriffe NNP cord-015369-72cjogxz 230 8 klar klar NNP cord-015369-72cjogxz 230 9 darzustellen darzustellen NNP cord-015369-72cjogxz 230 10 und und IN cord-015369-72cjogxz 231 1 ihre ihre NNP cord-015369-72cjogxz 231 2 gesetzlichen gesetzlichen NNP cord-015369-72cjogxz 231 3 Grundlagen Grundlagen NNP cord-015369-72cjogxz 231 4 aufzuzeigen aufzuzeigen NNP cord-015369-72cjogxz 231 5 . . . cord-015369-72cjogxz 232 1 Methodik Methodik NNP cord-015369-72cjogxz 232 2 . . . cord-015369-72cjogxz 233 1 Identifikation identifikation NN cord-015369-72cjogxz 233 2 der der NN cord-015369-72cjogxz 233 3 gesetzlichen gesetzlichen NN cord-015369-72cjogxz 233 4 Grundlagen Grundlagen NNP cord-015369-72cjogxz 233 5 mit mit NNP cord-015369-72cjogxz 233 6 Hilfe Hilfe NNP cord-015369-72cjogxz 233 7 des des FW cord-015369-72cjogxz 233 8 österreichischen österreichischen NNP cord-015369-72cjogxz 233 9 Rechtsinformationssystems Rechtsinformationssystems NNP cord-015369-72cjogxz 233 10 , , , cord-015369-72cjogxz 233 11 Pubmed Pubmed NNP cord-015369-72cjogxz 233 12 Suche Suche NNP cord-015369-72cjogxz 233 13 und und IN cord-015369-72cjogxz 233 14 Google Google NNP cord-015369-72cjogxz 233 15 Suche Suche NNP cord-015369-72cjogxz 233 16 . . . cord-015369-72cjogxz 234 1 Diese Diese NNP cord-015369-72cjogxz 234 2 Daten Daten NNP cord-015369-72cjogxz 234 3 werden werden NNP cord-015369-72cjogxz 234 4 verknüpft verknüpft NNS cord-015369-72cjogxz 234 5 und und IN cord-015369-72cjogxz 234 6 zur zur NNP cord-015369-72cjogxz 234 7 Begriffsbestimmung Begriffsbestimmung NNP cord-015369-72cjogxz 234 8 verwendet verwendet NNP cord-015369-72cjogxz 234 9 . . . cord-015369-72cjogxz 235 1 Es Es NNP cord-015369-72cjogxz 235 2 werden werden NNP cord-015369-72cjogxz 235 3 die die VBP cord-015369-72cjogxz 235 4 jeweiligen jeweiligen JJ cord-015369-72cjogxz 235 5 Rahmenbedingungen Rahmenbedingungen NNP cord-015369-72cjogxz 235 6 zur zur NNP cord-015369-72cjogxz 235 7 Anwendung Anwendung NNP cord-015369-72cjogxz 235 8 dargestellt dargestellt NNP cord-015369-72cjogxz 236 1 und und NNP cord-015369-72cjogxz 237 1 die die VB cord-015369-72cjogxz 238 1 Auswirkungen Auswirkungen NNP cord-015369-72cjogxz 238 2 auf auf NNP cord-015369-72cjogxz 238 3 die die VBP cord-015369-72cjogxz 238 4 ärztliche ärztliche NNP cord-015369-72cjogxz 238 5 Haftung Haftung NNP cord-015369-72cjogxz 238 6 aufgezeigt aufgezeigt NNP cord-015369-72cjogxz 238 7 . . . cord-015369-72cjogxz 239 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 239 2 . . . cord-015369-72cjogxz 240 1 Auflistung Auflistung NNP cord-015369-72cjogxz 240 2 der der NNP cord-015369-72cjogxz 240 3 entsprechenden entsprechenden NNP cord-015369-72cjogxz 240 4 österreichischen österreichischen NNP cord-015369-72cjogxz 241 1 Gesetze Gesetze NNP cord-015369-72cjogxz 241 2 sowie sowie JJ cord-015369-72cjogxz 241 3 EU EU NNP cord-015369-72cjogxz 241 4 Verordnungen Verordnungen NNP cord-015369-72cjogxz 241 5 und und IN cord-015369-72cjogxz 241 6 Richtlinien Richtlinien NNP cord-015369-72cjogxz 241 7 . . . cord-015369-72cjogxz 242 1 Die die VB cord-015369-72cjogxz 242 2 Begriffe Begriffe NNP cord-015369-72cjogxz 242 3 Offlabel Offlabel NNP cord-015369-72cjogxz 242 4 und und IN cord-015369-72cjogxz 243 1 Offlicence Offlicence NNP cord-015369-72cjogxz 243 2 sind sind NN cord-015369-72cjogxz 244 1 i -PRON- PRP cord-015369-72cjogxz 244 2 m be VBP cord-015369-72cjogxz 245 1 österreichischen österreichischen NNP cord-015369-72cjogxz 246 1 Recht Recht NNP cord-015369-72cjogxz 246 2 als als NNP cord-015369-72cjogxz 246 3 Rechtsbegriffe Rechtsbegriffe NNP cord-015369-72cjogxz 246 4 fremd fremd NNP cord-015369-72cjogxz 246 5 , , , cord-015369-72cjogxz 246 6 dennoch dennoch NNP cord-015369-72cjogxz 246 7 finden finden NNP cord-015369-72cjogxz 246 8 sich sich NNP cord-015369-72cjogxz 246 9 i -PRON- PRP cord-015369-72cjogxz 246 10 m be VBP cord-015369-72cjogxz 246 11 Arzneimittelgesetz Arzneimittelgesetz NNP cord-015369-72cjogxz 246 12 entsprechend entsprechend NNP cord-015369-72cjogxz 246 13 anwendbare anwendbare NNP cord-015369-72cjogxz 246 14 Rahmenbedingungen Rahmenbedingungen NNP cord-015369-72cjogxz 246 15 , , , cord-015369-72cjogxz 246 16 dem dem NNP cord-015369-72cjogxz 246 17 jedoch jedoch NNP cord-015369-72cjogxz 246 18 zum zum NNP cord-015369-72cjogxz 246 19 Teil Teil NNP cord-015369-72cjogxz 246 20 die die VB cord-015369-72cjogxz 247 1 Bestimmungen Bestimmungen NNP cord-015369-72cjogxz 248 1 i -PRON- PRP cord-015369-72cjogxz 248 2 m be VBP cord-015369-72cjogxz 248 3 Allgemeinen Allgemeinen NNP cord-015369-72cjogxz 248 4 Sozialversicherungsgesetz Sozialversicherungsgesetz NNP cord-015369-72cjogxz 248 5 gegenüber gegenüber NNP cord-015369-72cjogxz 248 6 stehen stehen NNP cord-015369-72cjogxz 248 7 . . . cord-015369-72cjogxz 249 1 Die die VB cord-015369-72cjogxz 250 1 Begriffe Begriffe NNP cord-015369-72cjogxz 250 2 Compassionate compassionate JJ cord-015369-72cjogxz 250 3 Use Use NNP cord-015369-72cjogxz 250 4 und und IN cord-015369-72cjogxz 250 5 Orphan Orphan NNP cord-015369-72cjogxz 250 6 Drug Drug NNP cord-015369-72cjogxz 250 7 sind sind NN cord-015369-72cjogxz 251 1 durch durch NNP cord-015369-72cjogxz 251 2 EU EU NNP cord-015369-72cjogxz 251 3 Verordnungen Verordnungen NNP cord-015369-72cjogxz 251 4 und und IN cord-015369-72cjogxz 251 5 Richtlinien Richtlinien NNP cord-015369-72cjogxz 251 6 geregelt geregelt NNP cord-015369-72cjogxz 251 7 . . . cord-015369-72cjogxz 252 1 Experimentelle Experimentelle NNP cord-015369-72cjogxz 252 2 Behandlung Behandlung NNP cord-015369-72cjogxz 252 3 ist ist NN cord-015369-72cjogxz 252 4 nach nach NN cord-015369-72cjogxz 252 5 dem dem NNP cord-015369-72cjogxz 252 6 Arzneimittel Arzneimittel NNP cord-015369-72cjogxz 252 7 - - HYPH cord-015369-72cjogxz 252 8 und und NNP cord-015369-72cjogxz 253 1 Medizinprodukte Medizinprodukte NNP cord-015369-72cjogxz 254 1 Gesetz Gesetz NNP cord-015369-72cjogxz 254 2 nur nur NNP cord-015369-72cjogxz 254 3 i -PRON- PRP cord-015369-72cjogxz 254 4 m be VBP cord-015369-72cjogxz 254 5 Rahmen Rahmen NNP cord-015369-72cjogxz 254 6 klinischer klinischer NNP cord-015369-72cjogxz 254 7 Prüfungen Prüfungen NNP cord-015369-72cjogxz 254 8 zulässig zulässig NNS cord-015369-72cjogxz 254 9 . . . cord-015369-72cjogxz 255 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 255 2 . . . cord-015369-72cjogxz 256 1 Alle Alle NNP cord-015369-72cjogxz 256 2 angeführten angeführten NNP cord-015369-72cjogxz 257 1 Modalitäten Modalitäten NNP cord-015369-72cjogxz 257 2 sind sind NNP cord-015369-72cjogxz 258 1 unter unter NNP cord-015369-72cjogxz 258 2 bestimmten bestimmten NNP cord-015369-72cjogxz 258 3 Rahmenbedingungen Rahmenbedingungen NNP cord-015369-72cjogxz 259 1 , , , cord-015369-72cjogxz 259 2 vor vor NNP cord-015369-72cjogxz 259 3 allem allem NNP cord-015369-72cjogxz 259 4 die die VB cord-015369-72cjogxz 259 5 qualifizierte qualifizierte NNP cord-015369-72cjogxz 259 6 Einwilligung Einwilligung NNP cord-015369-72cjogxz 259 7 , , , cord-015369-72cjogxz 259 8 in in IN cord-015369-72cjogxz 259 9 Ö Ö NNP cord-015369-72cjogxz 259 10 sterreich sterreich NN cord-015369-72cjogxz 259 11 zulässig zulässig NNS cord-015369-72cjogxz 259 12 . . . cord-015369-72cjogxz 260 1 Allerdings Allerdings NNP cord-015369-72cjogxz 260 2 kann kann NNP cord-015369-72cjogxz 260 3 dabei dabei NNP cord-015369-72cjogxz 260 4 die die NNP cord-015369-72cjogxz 261 1 Haftung Haftung NNP cord-015369-72cjogxz 261 2 vom vom NNP cord-015369-72cjogxz 262 1 Hersteller Hersteller NNP cord-015369-72cjogxz 262 2 vollständig vollständig NNP cord-015369-72cjogxz 263 1 auf auf NNP cord-015369-72cjogxz 263 2 den den NNP cord-015369-72cjogxz 263 3 behandelnden behandelnden NNP cord-015369-72cjogxz 263 4 Arzt/ Arzt/ NNP cord-015369-72cjogxz 263 5 Ä Ä NNP cord-015369-72cjogxz 263 6 rztin rztin NNP cord-015369-72cjogxz 263 7 übergehen übergehen NNP cord-015369-72cjogxz 263 8 . . . cord-015369-72cjogxz 264 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 264 2 . . . cord-015369-72cjogxz 265 1 Abseits Abseits NNP cord-015369-72cjogxz 265 2 von von NNP cord-015369-72cjogxz 265 3 klassischen klassischen NNP cord-015369-72cjogxz 265 4 Arzneimittel-(AMG arzneimittel-(amg CD cord-015369-72cjogxz 265 5 ) ) -RRB- cord-015369-72cjogxz 266 1 und und IN cord-015369-72cjogxz 266 2 Medizinprodukt-(MPG medizinprodukt-(mpg CD cord-015369-72cjogxz 266 3 ) ) -RRB- cord-015369-72cjogxz 267 1 Studien Studien NNP cord-015369-72cjogxz 268 1 gibt gibt NNP cord-015369-72cjogxz 269 1 es es NNP cord-015369-72cjogxz 269 2 immer immer NNP cord-015369-72cjogxz 269 3 wieder wieder NNP cord-015369-72cjogxz 270 1 Unklarheiten Unklarheiten NNP cord-015369-72cjogxz 270 2 ob ob NNP cord-015369-72cjogxz 270 3 die die VBP cord-015369-72cjogxz 271 1 Ethikkommission Ethikkommission NNP cord-015369-72cjogxz 271 2 zu zu IN cord-015369-72cjogxz 271 3 beschäftigen beschäftigen NNP cord-015369-72cjogxz 271 4 ist ist NNP cord-015369-72cjogxz 271 5 oder oder NNP cord-015369-72cjogxz 271 6 nicht nicht NNP cord-015369-72cjogxz 271 7 . . . cord-015369-72cjogxz 272 1 Die die VB cord-015369-72cjogxz 272 2 vorliegende vorliegende NNP cord-015369-72cjogxz 273 1 Arbeit Arbeit NNP cord-015369-72cjogxz 273 2 analysiert analysiert NNP cord-015369-72cjogxz 273 3 dazu dazu NNP cord-015369-72cjogxz 273 4 die die VBP cord-015369-72cjogxz 273 5 gesetzlichen gesetzlichen NNP cord-015369-72cjogxz 273 6 Grundlagen Grundlagen NNP cord-015369-72cjogxz 273 7 Ö Ö NNP cord-015369-72cjogxz 273 8 sterreichs sterreichs NN cord-015369-72cjogxz 273 9 , , , cord-015369-72cjogxz 273 10 der der NN cord-015369-72cjogxz 273 11 EU EU NNP cord-015369-72cjogxz 274 1 und und NNP cord-015369-72cjogxz 274 2 internationaler internationaler NNP cord-015369-72cjogxz 275 1 Organisationen Organisationen NNP cord-015369-72cjogxz 275 2 , , , cord-015369-72cjogxz 275 3 sowie sowie JJ cord-015369-72cjogxz 275 4 zusätzliche zusätzliche NNP cord-015369-72cjogxz 275 5 Bestimmungen Bestimmungen NNP cord-015369-72cjogxz 275 6 der der NNP cord-015369-72cjogxz 275 7 österreichischen österreichischen NNP cord-015369-72cjogxz 275 8 Medizinuniversitäten Medizinuniversitäten NNP cord-015369-72cjogxz 275 9 . . . cord-015369-72cjogxz 276 1 Methodik Methodik NNP cord-015369-72cjogxz 276 2 . . . cord-015369-72cjogxz 277 1 Identifikation identifikation NN cord-015369-72cjogxz 277 2 der der NN cord-015369-72cjogxz 277 3 gesetzlichen gesetzlichen NN cord-015369-72cjogxz 277 4 Grundlagen Grundlagen NNP cord-015369-72cjogxz 277 5 mit mit NNP cord-015369-72cjogxz 277 6 Hilfe Hilfe NNP cord-015369-72cjogxz 277 7 des des FW cord-015369-72cjogxz 277 8 österreichischen österreichischen NN cord-015369-72cjogxz 277 9 und und IN cord-015369-72cjogxz 277 10 EU EU NNP cord-015369-72cjogxz 277 11 - - HYPH cord-015369-72cjogxz 277 12 Rechtsinformationssystems Rechtsinformationssystems NNP cord-015369-72cjogxz 277 13 , , , cord-015369-72cjogxz 277 14 Pubmed Pubmed NNP cord-015369-72cjogxz 277 15 Suche Suche NNP cord-015369-72cjogxz 277 16 und und IN cord-015369-72cjogxz 277 17 Google Google NNP cord-015369-72cjogxz 277 18 Suche Suche NNP cord-015369-72cjogxz 277 19 . . . cord-015369-72cjogxz 278 1 Die die VB cord-015369-72cjogxz 278 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 278 3 werden werden NNP cord-015369-72cjogxz 278 4 nach nach NNP cord-015369-72cjogxz 278 5 rechtlicher rechtlicher NNP cord-015369-72cjogxz 279 1 Bindung Bindung NNP cord-015369-72cjogxz 279 2 vom vom NNP cord-015369-72cjogxz 279 3 nationalen nationalen NNP cord-015369-72cjogxz 279 4 Recht Recht NNP cord-015369-72cjogxz 279 5 bis bis NNP cord-015369-72cjogxz 279 6 zu zu NNP cord-015369-72cjogxz 279 7 internationalen internationalen NNP cord-015369-72cjogxz 279 8 Empfehlungen Empfehlungen NNP cord-015369-72cjogxz 279 9 dargestellt dargestellt NNP cord-015369-72cjogxz 279 10 . . . cord-015369-72cjogxz 280 1 Es Es NNP cord-015369-72cjogxz 280 2 werden werden NNP cord-015369-72cjogxz 280 3 die die VBP cord-015369-72cjogxz 281 1 Strafbestimmungen Strafbestimmungen NNP cord-015369-72cjogxz 281 2 i -PRON- PRP cord-015369-72cjogxz 281 3 m be VBP cord-015369-72cjogxz 281 4 Zusammenhang Zusammenhang NNP cord-015369-72cjogxz 281 5 mit mit NNP cord-015369-72cjogxz 281 6 Studien Studien NNP cord-015369-72cjogxz 281 7 analysiert analysiert NN cord-015369-72cjogxz 281 8 . . . cord-015369-72cjogxz 282 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 282 2 . . . cord-015369-72cjogxz 283 1 In in IN cord-015369-72cjogxz 283 2 Ö Ö NNP cord-015369-72cjogxz 283 3 sterreich sterreich JJ cord-015369-72cjogxz 283 4 gibt gibt NNP cord-015369-72cjogxz 283 5 es es NNP cord-015369-72cjogxz 283 6 drei drei NNP cord-015369-72cjogxz 283 7 Arten Arten NNP cord-015369-72cjogxz 283 8 von von NNP cord-015369-72cjogxz 283 9 Ethikkommissionen Ethikkommissionen NNP cord-015369-72cjogxz 283 10 : : : cord-015369-72cjogxz 283 11 Forschungs- Forschungs- NNP cord-015369-72cjogxz 283 12 , , , cord-015369-72cjogxz 283 13 Klinische Klinische NNP cord-015369-72cjogxz 283 14 - - HYPH cord-015369-72cjogxz 283 15 und und NNP cord-015369-72cjogxz 283 16 Bio Bio NNP cord-015369-72cjogxz 283 17 - - HYPH cord-015369-72cjogxz 283 18 Ethikkommission Ethikkommission NNP cord-015369-72cjogxz 283 19 . . . cord-015369-72cjogxz 284 1 Für Für NNP cord-015369-72cjogxz 284 2 die die VBP cord-015369-72cjogxz 284 3 klinische klinische NN cord-015369-72cjogxz 285 1 Forschung Forschung NNP cord-015369-72cjogxz 285 2 beschränkt beschränkt NNP cord-015369-72cjogxz 285 3 sich sich NNP cord-015369-72cjogxz 285 4 die die VBP cord-015369-72cjogxz 285 5 weitere weitere NNP cord-015369-72cjogxz 286 1 Analyse analyse VB cord-015369-72cjogxz 286 2 auf auf NNP cord-015369-72cjogxz 286 3 die die VB cord-015369-72cjogxz 286 4 Forschungs Forschungs NNP cord-015369-72cjogxz 286 5 - - HYPH cord-015369-72cjogxz 286 6 Ethikkommission Ethikkommission NNP cord-015369-72cjogxz 286 7 . . . cord-015369-72cjogxz 287 1 Die die VB cord-015369-72cjogxz 287 2 österreichischen österreichischen NN cord-015369-72cjogxz 287 3 gesetzlichen gesetzlichen NN cord-015369-72cjogxz 287 4 Grundlagen Grundlagen NNP cord-015369-72cjogxz 287 5 reichen reichen NNP cord-015369-72cjogxz 287 6 vom vom NNP cord-015369-72cjogxz 287 7 Arzneimittelgesetz Arzneimittelgesetz NNP cord-015369-72cjogxz 287 8 ( ( -LRB- cord-015369-72cjogxz 287 9 AMG AMG NNP cord-015369-72cjogxz 287 10 ) ) -RRB- cord-015369-72cjogxz 288 1 bis bis NNP cord-015369-72cjogxz 288 2 zum zum NNP cord-015369-72cjogxz 288 3 Universitätsgesetz Universitätsgesetz NNP cord-015369-72cjogxz 288 4 ( ( -LRB- cord-015369-72cjogxz 288 5 UG UG NNP cord-015369-72cjogxz 288 6 ) ) -RRB- cord-015369-72cjogxz 288 7 , , . cord-015369-72cjogxz 289 1 hinzu hinzu NNP cord-015369-72cjogxz 289 2 kommen kommen NNP cord-015369-72cjogxz 289 3 die die VBP cord-015369-72cjogxz 289 4 universitären universitären NNP cord-015369-72cjogxz 289 5 GSP GSP NNP cord-015369-72cjogxz 289 6 Bestimmungen Bestimmungen NNP cord-015369-72cjogxz 289 7 und und XX cord-015369-72cjogxz 290 1 zahlreiche zahlreiche NNP cord-015369-72cjogxz 290 2 Sonderfälle Sonderfälle NNP cord-015369-72cjogxz 290 3 von von NNP cord-015369-72cjogxz 290 4 Anwendungsbeobachtungen Anwendungsbeobachtungen NNP cord-015369-72cjogxz 290 5 bis bis NNP cord-015369-72cjogxz 290 6 zu zu NNP cord-015369-72cjogxz 290 7 Biodatenbanken Biodatenbanken NNP cord-015369-72cjogxz 290 8 . . . cord-015369-72cjogxz 291 1 Auf Auf NNP cord-015369-72cjogxz 291 2 EU EU NNP cord-015369-72cjogxz 291 3 Ebene Ebene NNP cord-015369-72cjogxz 291 4 ist ist NN cord-015369-72cjogxz 291 5 die die VBP cord-015369-72cjogxz 292 1 RL RL NNP cord-015369-72cjogxz 292 2 2001/20 2001/20 CD cord-015369-72cjogxz 292 3 / / SYM cord-015369-72cjogxz 292 4 EG EG NNP cord-015369-72cjogxz 292 5 und und XX cord-015369-72cjogxz 293 1 RL RL NNP cord-015369-72cjogxz 293 2 2005/28 2005/28 CD cord-015369-72cjogxz 293 3 / / SYM cord-015369-72cjogxz 293 4 EG EG NNP cord-015369-72cjogxz 293 5 maßgeblich maßgeblich NNP cord-015369-72cjogxz 293 6 , , , cord-015369-72cjogxz 293 7 international international JJ cord-015369-72cjogxz 293 8 die die VBP cord-015369-72cjogxz 293 9 ICH ICH NNP cord-015369-72cjogxz 293 10 , , , cord-015369-72cjogxz 293 11 GCP GCP NNP cord-015369-72cjogxz 293 12 und und XX cord-015369-72cjogxz 294 1 WHO who WP cord-015369-72cjogxz 294 2 Richtlinie Richtlinie NNP cord-015369-72cjogxz 294 3 für für IN cord-015369-72cjogxz 294 4 Ethikkommissionen Ethikkommissionen NNP cord-015369-72cjogxz 294 5 . . . cord-015369-72cjogxz 295 1 Fü fü NN cord-015369-72cjogxz 296 1 r r LS cord-015369-72cjogxz 296 2 die die VB cord-015369-72cjogxz 297 1 Publikation Publikation NNP cord-015369-72cjogxz 297 2 können können NNP cord-015369-72cjogxz 297 3 zusätzliche zusätzliche NNP cord-015369-72cjogxz 298 1 Anforderungen Anforderungen NNP cord-015369-72cjogxz 298 2 wie wie NNP cord-015369-72cjogxz 298 3 z. z. NN cord-015369-72cjogxz 299 1 B. B. NNP cord-015369-72cjogxz 299 2 von von NNP cord-015369-72cjogxz 299 3 WAME WAME NNP cord-015369-72cjogxz 299 4 ( ( -LRB- cord-015369-72cjogxz 299 5 World World NNP cord-015369-72cjogxz 299 6 Assocation Assocation NNP cord-015369-72cjogxz 299 7 of of IN cord-015369-72cjogxz 299 8 Medical Medical NNP cord-015369-72cjogxz 299 9 Editors Editors NNPS cord-015369-72cjogxz 299 10 ) ) -RRB- cord-015369-72cjogxz 300 1 und und NNP cord-015369-72cjogxz 301 1 ICMJE ICMJE NNP cord-015369-72cjogxz 301 2 ( ( -LRB- cord-015369-72cjogxz 301 3 International International NNP cord-015369-72cjogxz 301 4 Committee Committee NNP cord-015369-72cjogxz 301 5 of of IN cord-015369-72cjogxz 301 6 Medical Medical NNP cord-015369-72cjogxz 301 7 Journal Journal NNP cord-015369-72cjogxz 301 8 Editors Editors NNPS cord-015369-72cjogxz 301 9 ) ) -RRB- cord-015369-72cjogxz 301 10 gestellt gestellt NNP cord-015369-72cjogxz 301 11 werden werden NNP cord-015369-72cjogxz 301 12 . . . cord-015369-72cjogxz 302 1 Die die VB cord-015369-72cjogxz 303 1 Strafbestimmungen Strafbestimmungen NNP cord-015369-72cjogxz 303 2 i -PRON- PRP cord-015369-72cjogxz 303 3 m be VBP cord-015369-72cjogxz 303 4 österreichischen österreichischen NNP cord-015369-72cjogxz 303 5 Recht Recht NNP cord-015369-72cjogxz 303 6 werden werden NNP cord-015369-72cjogxz 303 7 aufgezeigt aufgezeigt NNP cord-015369-72cjogxz 303 8 . . . cord-015369-72cjogxz 304 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 304 2 . . . cord-015369-72cjogxz 305 1 Die die VB cord-015369-72cjogxz 305 2 dargestellte dargestellte NNP cord-015369-72cjogxz 305 3 rechtliche rechtliche NN cord-015369-72cjogxz 305 4 Situation Situation NNP cord-015369-72cjogxz 305 5 ist ist NNP cord-015369-72cjogxz 305 6 überaus überaus NNP cord-015369-72cjogxz 305 7 komplex komplex NNP cord-015369-72cjogxz 305 8 , , , cord-015369-72cjogxz 305 9 deshalb deshalb NNP cord-015369-72cjogxz 305 10 wird wird NNP cord-015369-72cjogxz 305 11 es es NNP cord-015369-72cjogxz 305 12 notwendig notwendig NNP cord-015369-72cjogxz 305 13 sein sein NNP cord-015369-72cjogxz 306 1 an an DT cord-015369-72cjogxz 306 2 Universitäten Universitäten NNP cord-015369-72cjogxz 306 3 aber aber NNP cord-015369-72cjogxz 306 4 auch auch NNP cord-015369-72cjogxz 306 5 extrauniversitär extrauniversitär NNP cord-015369-72cjogxz 306 6 entsprechende entsprechende NNP cord-015369-72cjogxz 306 7 Beratungsstellen Beratungsstellen NNP cord-015369-72cjogxz 306 8 einzurichten einzurichten NNP cord-015369-72cjogxz 306 9 . . . cord-015369-72cjogxz 307 1 Die die VB cord-015369-72cjogxz 307 2 zunehmenden zunehmenden NNP cord-015369-72cjogxz 308 1 Anforderungen Anforderungen NNP cord-015369-72cjogxz 308 2 werden werden NNP cord-015369-72cjogxz 309 1 zu zu NNP cord-015369-72cjogxz 309 2 einer einer NNP cord-015369-72cjogxz 309 3 Ü Ü NNP cord-015369-72cjogxz 309 4 berhäufung berhäufung NNP cord-015369-72cjogxz 309 5 der der NNP cord-015369-72cjogxz 309 6 Ethikkommissionen Ethikkommissionen NNP cord-015369-72cjogxz 309 7 mit mit NNP cord-015369-72cjogxz 309 8 Anträgen Anträgen NNP cord-015369-72cjogxz 309 9 führen führen NNP cord-015369-72cjogxz 309 10 . . . cord-015369-72cjogxz 310 1 Ein Ein NNP cord-015369-72cjogxz 310 2 möglicher möglicher NN cord-015369-72cjogxz 310 3 Ausweg Ausweg NNP cord-015369-72cjogxz 310 4 ist ist NN cord-015369-72cjogxz 310 5 die die VBP cord-015369-72cjogxz 310 6 Trennung Trennung NNP cord-015369-72cjogxz 310 7 in in IN cord-015369-72cjogxz 310 8 Begutachtungspflicht Begutachtungspflicht NNP cord-015369-72cjogxz 310 9 ( ( -LRB- cord-015369-72cjogxz 310 10 für für NNP cord-015369-72cjogxz 310 11 AMG AMG NNP cord-015369-72cjogxz 310 12 / / SYM cord-015369-72cjogxz 310 13 MPG MPG NNP cord-015369-72cjogxz 310 14 Studien Studien NNP cord-015369-72cjogxz 310 15 ) ) -RRB- cord-015369-72cjogxz 311 1 und und NNP cord-015369-72cjogxz 312 1 Beratungspflicht Beratungspflicht NNP cord-015369-72cjogxz 312 2 wie wie VBP cord-015369-72cjogxz 312 3 in in IN cord-015369-72cjogxz 312 4 Deutschland Deutschland NNP cord-015369-72cjogxz 312 5 sowie sowie XX cord-015369-72cjogxz 313 1 die die VB cord-015369-72cjogxz 313 2 Einführung Einführung NNP cord-015369-72cjogxz 313 3 von von NNP cord-015369-72cjogxz 313 4 Institutional Institutional NNP cord-015369-72cjogxz 313 5 Review Review NNP cord-015369-72cjogxz 313 6 - - HYPH cord-015369-72cjogxz 313 7 Boards Boards NNP cord-015369-72cjogxz 313 8 als als NN cord-015369-72cjogxz 313 9 Filter filter NN cord-015369-72cjogxz 313 10 zwischen zwischen NNP cord-015369-72cjogxz 313 11 ForscherInnen ForscherInnen NNP cord-015369-72cjogxz 313 12 und und IN cord-015369-72cjogxz 313 13 Ethikkommissionen Ethikkommissionen NNP cord-015369-72cjogxz 313 14 . . . cord-015369-72cjogxz 314 1 Background background NN cord-015369-72cjogxz 314 2 . . . cord-015369-72cjogxz 315 1 EGFR EGFR NNP cord-015369-72cjogxz 315 2 - - HYPH cord-015369-72cjogxz 315 3 targeted target VBN cord-015369-72cjogxz 315 4 therapies therapy NNS cord-015369-72cjogxz 315 5 are be VBP cord-015369-72cjogxz 315 6 a a DT cord-015369-72cjogxz 315 7 novel novel JJ cord-015369-72cjogxz 315 8 and and CC cord-015369-72cjogxz 315 9 very very RB cord-015369-72cjogxz 315 10 effective effective JJ cord-015369-72cjogxz 315 11 chemotherapeutic chemotherapeutic JJ cord-015369-72cjogxz 315 12 approach approach NN cord-015369-72cjogxz 315 13 for for IN cord-015369-72cjogxz 315 14 advanced advanced JJ cord-015369-72cjogxz 315 15 NSCLC NSCLC NNP cord-015369-72cjogxz 315 16 . . . cord-015369-72cjogxz 316 1 How how WRB cord-015369-72cjogxz 316 2 - - : cord-015369-72cjogxz 316 3 ever ever RB cord-015369-72cjogxz 316 4 , , , cord-015369-72cjogxz 316 5 the the DT cord-015369-72cjogxz 316 6 predictive predictive JJ cord-015369-72cjogxz 316 7 factors factor NNS cord-015369-72cjogxz 316 8 for for IN cord-015369-72cjogxz 316 9 therapeutic therapeutic JJ cord-015369-72cjogxz 316 10 response response NN cord-015369-72cjogxz 316 11 are be VBP cord-015369-72cjogxz 316 12 not not RB cord-015369-72cjogxz 316 13 entirely entirely RB cord-015369-72cjogxz 316 14 known know VBN cord-015369-72cjogxz 316 15 . . . cord-015369-72cjogxz 317 1 One one CD cord-015369-72cjogxz 317 2 of of IN cord-015369-72cjogxz 317 3 the the DT cord-015369-72cjogxz 317 4 reasons reason NNS cord-015369-72cjogxz 317 5 of of IN cord-015369-72cjogxz 317 6 therapy therapy NN cord-015369-72cjogxz 317 7 failure failure NN cord-015369-72cjogxz 317 8 might may MD cord-015369-72cjogxz 317 9 be be VB cord-015369-72cjogxz 317 10 the the DT cord-015369-72cjogxz 317 11 change change NN cord-015369-72cjogxz 317 12 of of IN cord-015369-72cjogxz 317 13 EGFR EGFR NNP cord-015369-72cjogxz 317 14 status status NN cord-015369-72cjogxz 317 15 during during IN cord-015369-72cjogxz 317 16 the the DT cord-015369-72cjogxz 317 17 course course NN cord-015369-72cjogxz 317 18 of of IN cord-015369-72cjogxz 317 19 disease disease NN cord-015369-72cjogxz 317 20 , , , cord-015369-72cjogxz 317 21 or or CC cord-015369-72cjogxz 317 22 an an DT cord-015369-72cjogxz 317 23 altered altered JJ cord-015369-72cjogxz 317 24 EGFR egfr NN cord-015369-72cjogxz 317 25 status status NN cord-015369-72cjogxz 317 26 in in IN cord-015369-72cjogxz 317 27 metastases metastasis NNS cord-015369-72cjogxz 317 28 as as IN cord-015369-72cjogxz 317 29 compared compare VBN cord-015369-72cjogxz 317 30 to to IN cord-015369-72cjogxz 317 31 the the DT cord-015369-72cjogxz 317 32 primary primary JJ cord-015369-72cjogxz 317 33 tumor tumor NN cord-015369-72cjogxz 317 34 . . . cord-015369-72cjogxz 318 1 Using use VBG cord-015369-72cjogxz 318 2 autopsy autopsy JJ cord-015369-72cjogxz 318 3 material material NN cord-015369-72cjogxz 318 4 , , , cord-015369-72cjogxz 318 5 we -PRON- PRP cord-015369-72cjogxz 318 6 compare compare VBP cord-015369-72cjogxz 318 7 here here RB cord-015369-72cjogxz 318 8 systematically systematically RB cord-015369-72cjogxz 318 9 the the DT cord-015369-72cjogxz 318 10 EGFR EGFR NNP cord-015369-72cjogxz 318 11 status status NN cord-015369-72cjogxz 318 12 of of IN cord-015369-72cjogxz 318 13 NSCLC NSCLC NNP cord-015369-72cjogxz 318 14 metastases metastasis NNS cord-015369-72cjogxz 318 15 with with IN cord-015369-72cjogxz 318 16 the the DT cord-015369-72cjogxz 318 17 primary primary JJ cord-015369-72cjogxz 318 18 tumor tumor NN cord-015369-72cjogxz 318 19 . . . cord-015369-72cjogxz 319 1 Methods method NNS cord-015369-72cjogxz 319 2 . . . cord-015369-72cjogxz 320 1 Autopsy autopsy JJ cord-015369-72cjogxz 320 2 cases case NNS cord-015369-72cjogxz 320 3 from from IN cord-015369-72cjogxz 320 4 our -PRON- PRP$ cord-015369-72cjogxz 320 5 institution institution NN cord-015369-72cjogxz 320 6 with with IN cord-015369-72cjogxz 320 7 metastatic metastatic JJ cord-015369-72cjogxz 320 8 NSCLC NSCLC NNP cord-015369-72cjogxz 320 9 have have VBP cord-015369-72cjogxz 320 10 been be VBN cord-015369-72cjogxz 320 11 retrieved retrieve VBN cord-015369-72cjogxz 320 12 from from IN cord-015369-72cjogxz 320 13 the the DT cord-015369-72cjogxz 320 14 archive archive NN cord-015369-72cjogxz 320 15 . . . cord-015369-72cjogxz 321 1 The the DT cord-015369-72cjogxz 321 2 specimens specimen NNS cord-015369-72cjogxz 321 3 of of IN cord-015369-72cjogxz 321 4 primary primary JJ cord-015369-72cjogxz 321 5 tumor tumor NN cord-015369-72cjogxz 321 6 and and CC cord-015369-72cjogxz 321 7 of of IN cord-015369-72cjogxz 321 8 all all DT cord-015369-72cjogxz 321 9 metastases metastasis NNS cord-015369-72cjogxz 321 10 have have VBP cord-015369-72cjogxz 321 11 been be VBN cord-015369-72cjogxz 321 12 stained stain VBN cord-015369-72cjogxz 321 13 by by IN cord-015369-72cjogxz 321 14 anti anti JJ cord-015369-72cjogxz 321 15 - - JJ cord-015369-72cjogxz 321 16 EGFR egfr JJ cord-015369-72cjogxz 321 17 and and CC cord-015369-72cjogxz 321 18 re re VB cord-015369-72cjogxz 321 19 - - VBN cord-015369-72cjogxz 321 20 evaluated evaluate VBN cord-015369-72cjogxz 321 21 by by IN cord-015369-72cjogxz 321 22 two two CD cord-015369-72cjogxz 321 23 independent independent JJ cord-015369-72cjogxz 321 24 observers observer NNS cord-015369-72cjogxz 321 25 . . . cord-015369-72cjogxz 322 1 In in IN cord-015369-72cjogxz 322 2 addition addition NN cord-015369-72cjogxz 322 3 , , , cord-015369-72cjogxz 322 4 basic basic JJ cord-015369-72cjogxz 322 5 clinical clinical JJ cord-015369-72cjogxz 322 6 parameters parameter NNS cord-015369-72cjogxz 322 7 have have VBP cord-015369-72cjogxz 322 8 been be VBN cord-015369-72cjogxz 322 9 retrieved retrieve VBN cord-015369-72cjogxz 322 10 from from IN cord-015369-72cjogxz 322 11 the the DT cord-015369-72cjogxz 322 12 charts chart NNS cord-015369-72cjogxz 322 13 . . . cord-015369-72cjogxz 323 1 The the DT cord-015369-72cjogxz 323 2 EGFR EGFR NNP cord-015369-72cjogxz 323 3 status status NN cord-015369-72cjogxz 323 4 in in IN cord-015369-72cjogxz 323 5 primary primary JJ cord-015369-72cjogxz 323 6 tumor tumor NN cord-015369-72cjogxz 323 7 and and CC cord-015369-72cjogxz 323 8 metastases metastasis NNS cord-015369-72cjogxz 323 9 has have VBZ cord-015369-72cjogxz 323 10 been be VBN cord-015369-72cjogxz 323 11 compared compare VBN cord-015369-72cjogxz 323 12 by by IN cord-015369-72cjogxz 323 13 statistical statistical JJ cord-015369-72cjogxz 323 14 means mean NNS cord-015369-72cjogxz 323 15 . . . cord-015369-72cjogxz 324 1 Results result NNS cord-015369-72cjogxz 324 2 . . . cord-015369-72cjogxz 325 1 We -PRON- PRP cord-015369-72cjogxz 325 2 examined examine VBD cord-015369-72cjogxz 325 3 a a DT cord-015369-72cjogxz 325 4 total total NN cord-015369-72cjogxz 325 5 of of IN cord-015369-72cjogxz 325 6 40 40 CD cord-015369-72cjogxz 325 7 patients patient NNS cord-015369-72cjogxz 325 8 . . . cord-015369-72cjogxz 326 1 The the DT cord-015369-72cjogxz 326 2 mean mean JJ cord-015369-72cjogxz 326 3 age age NN cord-015369-72cjogxz 326 4 at at IN cord-015369-72cjogxz 326 5 death death NN cord-015369-72cjogxz 326 6 was be VBD cord-015369-72cjogxz 326 7 67.5 67.5 CD cord-015369-72cjogxz 326 8 years year NNS cord-015369-72cjogxz 326 9 ; ; : cord-015369-72cjogxz 326 10 the the DT cord-015369-72cjogxz 326 11 male male NN cord-015369-72cjogxz 326 12 : : : cord-015369-72cjogxz 326 13 female female JJ cord-015369-72cjogxz 326 14 ratio ratio NN cord-015369-72cjogxz 326 15 was be VBD cord-015369-72cjogxz 326 16 3:1 3:1 CD cord-015369-72cjogxz 326 17 . . . cord-015369-72cjogxz 327 1 Most Most JJS cord-015369-72cjogxz 327 2 patients patient NNS cord-015369-72cjogxz 327 3 suffered suffer VBD cord-015369-72cjogxz 327 4 from from IN cord-015369-72cjogxz 327 5 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 327 6 ( ( -LRB- cord-015369-72cjogxz 327 7 62.5 62.5 CD cord-015369-72cjogxz 327 8 % % NN cord-015369-72cjogxz 327 9 ) ) -RRB- cord-015369-72cjogxz 327 10 . . . cord-015369-72cjogxz 328 1 Most Most JJS cord-015369-72cjogxz 328 2 patients patient NNS cord-015369-72cjogxz 328 3 were be VBD cord-015369-72cjogxz 328 4 in in IN cord-015369-72cjogxz 328 5 stage stage NN cord-015369-72cjogxz 328 6 IV IV NNP cord-015369-72cjogxz 328 7 with with IN cord-015369-72cjogxz 328 8 multiple multiple JJ cord-015369-72cjogxz 328 9 metastases metastasis NNS cord-015369-72cjogxz 328 10 at at IN cord-015369-72cjogxz 328 11 19 19 CD cord-015369-72cjogxz 328 12 different different JJ cord-015369-72cjogxz 328 13 body body NN cord-015369-72cjogxz 328 14 sites site NNS cord-015369-72cjogxz 328 15 . . . cord-015369-72cjogxz 329 1 While while IN cord-015369-72cjogxz 329 2 all all DT cord-015369-72cjogxz 329 3 primary primary JJ cord-015369-72cjogxz 329 4 tumors tumor NNS cord-015369-72cjogxz 329 5 were be VBD cord-015369-72cjogxz 329 6 EGFR EGFR NNP cord-015369-72cjogxz 329 7 - - HYPH cord-015369-72cjogxz 329 8 positive positive JJ cord-015369-72cjogxz 329 9 , , , cord-015369-72cjogxz 329 10 only only RB cord-015369-72cjogxz 329 11 in in IN cord-015369-72cjogxz 329 12 2 2 CD cord-015369-72cjogxz 329 13 cases case NNS cord-015369-72cjogxz 329 14 metastases metastasis NNS cord-015369-72cjogxz 329 15 were be VBD cord-015369-72cjogxz 329 16 EGFR egfr NN cord-015369-72cjogxz 329 17 - - HYPH cord-015369-72cjogxz 329 18 negative negative JJ cord-015369-72cjogxz 329 19 . . . cord-015369-72cjogxz 330 1 Both both DT cord-015369-72cjogxz 330 2 EGFR EGFR NNP cord-015369-72cjogxz 330 3 staining staining NN cord-015369-72cjogxz 330 4 intensity intensity NN cord-015369-72cjogxz 330 5 and and CC cord-015369-72cjogxz 330 6 extension extension NN cord-015369-72cjogxz 330 7 of of IN cord-015369-72cjogxz 330 8 EGFR EGFR NNP cord-015369-72cjogxz 330 9 - - HYPH cord-015369-72cjogxz 330 10 positive positive JJ cord-015369-72cjogxz 330 11 cells cell NNS cord-015369-72cjogxz 330 12 were be VBD cord-015369-72cjogxz 330 13 in in IN cord-015369-72cjogxz 330 14 most most JJS cord-015369-72cjogxz 330 15 cases case NNS cord-015369-72cjogxz 330 16 identical identical JJ cord-015369-72cjogxz 330 17 . . . cord-015369-72cjogxz 331 1 Thus thus RB cord-015369-72cjogxz 331 2 , , , cord-015369-72cjogxz 331 3 statistical statistical JJ cord-015369-72cjogxz 331 4 analysis analysis NN cord-015369-72cjogxz 331 5 failed fail VBD cord-015369-72cjogxz 331 6 to to TO cord-015369-72cjogxz 331 7 detect detect VB cord-015369-72cjogxz 331 8 a a DT cord-015369-72cjogxz 331 9 significant significant JJ cord-015369-72cjogxz 331 10 difference difference NN cord-015369-72cjogxz 331 11 in in IN cord-015369-72cjogxz 331 12 staining stain VBG cord-015369-72cjogxz 331 13 behavior behavior NN cord-015369-72cjogxz 331 14 between between IN cord-015369-72cjogxz 331 15 primary primary JJ cord-015369-72cjogxz 331 16 tumor tumor NN cord-015369-72cjogxz 331 17 and and CC cord-015369-72cjogxz 331 18 metastases metastasis NNS cord-015369-72cjogxz 331 19 . . . cord-015369-72cjogxz 332 1 Conclusions conclusion NNS cord-015369-72cjogxz 332 2 . . . cord-015369-72cjogxz 333 1 The the DT cord-015369-72cjogxz 333 2 expression expression NN cord-015369-72cjogxz 333 3 of of IN cord-015369-72cjogxz 333 4 EGFR EGFR NNP cord-015369-72cjogxz 333 5 in in IN cord-015369-72cjogxz 333 6 metastases metastasis NNS cord-015369-72cjogxz 333 7 of of IN cord-015369-72cjogxz 333 8 NSCLC NSCLC NNP cord-015369-72cjogxz 333 9 is be VBZ cord-015369-72cjogxz 333 10 almost almost RB cord-015369-72cjogxz 333 11 identical identical JJ cord-015369-72cjogxz 333 12 to to IN cord-015369-72cjogxz 333 13 EGFR EGFR NNP cord-015369-72cjogxz 333 14 expression expression NN cord-015369-72cjogxz 333 15 in in IN cord-015369-72cjogxz 333 16 the the DT cord-015369-72cjogxz 333 17 primary primary JJ cord-015369-72cjogxz 333 18 tumor tumor NN cord-015369-72cjogxz 333 19 . . . cord-015369-72cjogxz 334 1 Thus thus RB cord-015369-72cjogxz 334 2 , , , cord-015369-72cjogxz 334 3 in in IN cord-015369-72cjogxz 334 4 EGFR egfr NN cord-015369-72cjogxz 334 5 - - HYPH cord-015369-72cjogxz 334 6 positive positive JJ cord-015369-72cjogxz 334 7 advanced advanced JJ cord-015369-72cjogxz 334 8 NSCLC NSCLC NNP cord-015369-72cjogxz 334 9 EGFR EGFR NNP cord-015369-72cjogxz 334 10 - - HYPH cord-015369-72cjogxz 334 11 targeted target VBN cord-015369-72cjogxz 334 12 therapy therapy NN cord-015369-72cjogxz 334 13 is be VBZ cord-015369-72cjogxz 334 14 reasonable reasonable JJ cord-015369-72cjogxz 334 15 . . . cord-015369-72cjogxz 335 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 335 2 . . . cord-015369-72cjogxz 336 1 Es Es NNP cord-015369-72cjogxz 336 2 erfolgte erfolgte NN cord-015369-72cjogxz 336 3 eine eine NN cord-015369-72cjogxz 336 4 retrospektive retrospektive NNP cord-015369-72cjogxz 337 1 Analyse Analyse NNP cord-015369-72cjogxz 337 2 der der NNP cord-015369-72cjogxz 337 3 stationär stationär NNP cord-015369-72cjogxz 337 4 und und IN cord-015369-72cjogxz 337 5 operativ operativ NNP cord-015369-72cjogxz 337 6 behandelten behandelten NNP cord-015369-72cjogxz 337 7 Handinfekte Handinfekte NNP cord-015369-72cjogxz 338 1 an an DT cord-015369-72cjogxz 338 2 unserer unserer JJ cord-015369-72cjogxz 338 3 Abteilung Abteilung NNP cord-015369-72cjogxz 338 4 der der NNP cord-015369-72cjogxz 338 5 letzten letzten NNP cord-015369-72cjogxz 338 6 9 9 CD cord-015369-72cjogxz 338 7 Jahre Jahre NNP cord-015369-72cjogxz 338 8 . . . cord-015369-72cjogxz 339 1 Methodik Methodik NNP cord-015369-72cjogxz 339 2 . . . cord-015369-72cjogxz 340 1 Die die VB cord-015369-72cjogxz 341 1 Krankengeschichten Krankengeschichten NNP cord-015369-72cjogxz 341 2 aller aller FW cord-015369-72cjogxz 341 3 Patienten Patienten NNP cord-015369-72cjogxz 341 4 die die VBP cord-015369-72cjogxz 341 5 an an DT cord-015369-72cjogxz 341 6 unserer unserer JJ cord-015369-72cjogxz 341 7 Abteilung Abteilung NNP cord-015369-72cjogxz 341 8 wegen wegen NNP cord-015369-72cjogxz 341 9 eines eines NNP cord-015369-72cjogxz 341 10 Handinfektes Handinfektes NNPS cord-015369-72cjogxz 341 11 zwischen zwischen NNP cord-015369-72cjogxz 341 12 2001 2001 CD cord-015369-72cjogxz 341 13 und und NNP cord-015369-72cjogxz 341 14 2008 2008 CD cord-015369-72cjogxz 341 15 operiert operiert NNP cord-015369-72cjogxz 341 16 wurden wurden NNP cord-015369-72cjogxz 341 17 sind sind NNP cord-015369-72cjogxz 341 18 retrospektiv retrospektiv NNP cord-015369-72cjogxz 341 19 ausgewertet ausgewertet NNP cord-015369-72cjogxz 341 20 worden worden NNP cord-015369-72cjogxz 341 21 . . . cord-015369-72cjogxz 342 1 Die die VB cord-015369-72cjogxz 342 2 Patienten Patienten NNP cord-015369-72cjogxz 342 3 wurden wurden NNS cord-015369-72cjogxz 342 4 in in IN cord-015369-72cjogxz 342 5 3 3 CD cord-015369-72cjogxz 342 6 Gruppen Gruppen NNP cord-015369-72cjogxz 342 7 eingeteilt eingeteilt NN cord-015369-72cjogxz 342 8 ( ( -LRB- cord-015369-72cjogxz 342 9 Panaritien Panaritien NNP cord-015369-72cjogxz 342 10 , , , cord-015369-72cjogxz 342 11 Spritzenabszesse Spritzenabszesse NNP cord-015369-72cjogxz 342 12 und und IN cord-015369-72cjogxz 342 13 Phlegmonen Phlegmonen NNP cord-015369-72cjogxz 342 14 ) ) -RRB- cord-015369-72cjogxz 342 15 und und NNP cord-015369-72cjogxz 342 16 miteinander miteinander NNP cord-015369-72cjogxz 342 17 verglichen verglichen NNP cord-015369-72cjogxz 342 18 . . . cord-015369-72cjogxz 343 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 343 2 . . . cord-015369-72cjogxz 344 1 Es Es NNP cord-015369-72cjogxz 344 2 wurden wurden VBD cord-015369-72cjogxz 344 3 131 131 CD cord-015369-72cjogxz 344 4 Patienten Patienten NNP cord-015369-72cjogxz 344 5 ( ( -LRB- cord-015369-72cjogxz 344 6 72 72 CD cord-015369-72cjogxz 344 7 Männer Männer NNP cord-015369-72cjogxz 344 8 , , , cord-015369-72cjogxz 344 9 59 59 CD cord-015369-72cjogxz 344 10 Frauen Frauen NNP cord-015369-72cjogxz 344 11 ) ) -RRB- cord-015369-72cjogxz 344 12 mit mit NNP cord-015369-72cjogxz 344 13 einem einem NNP cord-015369-72cjogxz 344 14 Durchschnittsalter Durchschnittsalter NNP cord-015369-72cjogxz 344 15 von von NNP cord-015369-72cjogxz 344 16 41 41 CD cord-015369-72cjogxz 344 17 Jahren Jahren NNP cord-015369-72cjogxz 344 18 operiert operiert NN cord-015369-72cjogxz 344 19 . . . cord-015369-72cjogxz 345 1 Am be VBP cord-015369-72cjogxz 345 2 häufigsten häufigsten NNP cord-015369-72cjogxz 345 3 zeigten zeigten NNP cord-015369-72cjogxz 345 4 sich sich NNP cord-015369-72cjogxz 345 5 Panaritien Panaritien NNP cord-015369-72cjogxz 345 6 ( ( -LRB- cord-015369-72cjogxz 345 7 58 58 CD cord-015369-72cjogxz 345 8 ) ) -RRB- cord-015369-72cjogxz 346 1 gefolgt gefolgt NNP cord-015369-72cjogxz 346 2 von von NNP cord-015369-72cjogxz 346 3 Phlegmonen Phlegmonen NNP cord-015369-72cjogxz 346 4 ( ( -LRB- cord-015369-72cjogxz 346 5 40 40 CD cord-015369-72cjogxz 346 6 ) ) -RRB- cord-015369-72cjogxz 346 7 und und NNP cord-015369-72cjogxz 346 8 Spritzenabszessen Spritzenabszessen NNP cord-015369-72cjogxz 346 9 ( ( -LRB- cord-015369-72cjogxz 346 10 33 33 CD cord-015369-72cjogxz 346 11 ) ) -RRB- cord-015369-72cjogxz 346 12 . . . cord-015369-72cjogxz 347 1 Die die VB cord-015369-72cjogxz 347 2 jüngste jüngste NNP cord-015369-72cjogxz 347 3 Patientengruppe Patientengruppe NNP cord-015369-72cjogxz 347 4 war war NN cord-015369-72cjogxz 347 5 mit mit NNP cord-015369-72cjogxz 347 6 durchschnittlich durchschnittlich NNP cord-015369-72cjogxz 347 7 28 28 CD cord-015369-72cjogxz 347 8 Jahren Jahren NNP cord-015369-72cjogxz 347 9 bei bei NNP cord-015369-72cjogxz 347 10 der der NNP cord-015369-72cjogxz 347 11 Operation Operation NNP cord-015369-72cjogxz 347 12 jene jene NNP cord-015369-72cjogxz 347 13 der der NNP cord-015369-72cjogxz 347 14 Spritzenabszesse Spritzenabszesse NNP cord-015369-72cjogxz 347 15 . . . cord-015369-72cjogxz 348 1 Ä Ä NNP cord-015369-72cjogxz 348 2 tiologisch tiologisch NNP cord-015369-72cjogxz 349 1 dominierten dominierten NNP cord-015369-72cjogxz 349 2 Traumata Traumata NNP cord-015369-72cjogxz 349 3 bei bei NNP cord-015369-72cjogxz 349 4 den den NNP cord-015369-72cjogxz 349 5 Panaritien Panaritien NNP cord-015369-72cjogxz 349 6 und und IN cord-015369-72cjogxz 349 7 Phlegmonen Phlegmonen NNP cord-015369-72cjogxz 349 8 bzw bzw NNP cord-015369-72cjogxz 349 9 . . . cord-015369-72cjogxz 350 1 Drogeninjektionen Drogeninjektionen NNP cord-015369-72cjogxz 350 2 bei bei NNP cord-015369-72cjogxz 350 3 den den NNP cord-015369-72cjogxz 350 4 Spritzenabszessen Spritzenabszessen NNP cord-015369-72cjogxz 350 5 . . . cord-015369-72cjogxz 351 1 Als Als NNP cord-015369-72cjogxz 351 2 Grunderkrankung Grunderkrankung NNP cord-015369-72cjogxz 351 3 zeigte zeigte NN cord-015369-72cjogxz 351 4 sich sich NNP cord-015369-72cjogxz 351 5 bei bei NNP cord-015369-72cjogxz 351 6 den den NNP cord-015369-72cjogxz 351 7 Panaritien Panaritien NNP cord-015369-72cjogxz 351 8 und und XX cord-015369-72cjogxz 352 1 Phlegmonen Phlegmonen NNP cord-015369-72cjogxz 352 2 eine eine NNP cord-015369-72cjogxz 352 3 Häufung Häufung NNP cord-015369-72cjogxz 352 4 von von NNP cord-015369-72cjogxz 352 5 Diabetes diabetes NN cord-015369-72cjogxz 352 6 und und IN cord-015369-72cjogxz 352 7 Immunsuppression Immunsuppression NNP cord-015369-72cjogxz 352 8 . . . cord-015369-72cjogxz 353 1 19 19 CD cord-015369-72cjogxz 353 2 von von NNP cord-015369-72cjogxz 353 3 33 33 CD cord-015369-72cjogxz 353 4 Patienten Patienten NNP cord-015369-72cjogxz 353 5 mit mit NNP cord-015369-72cjogxz 353 6 Spritzenabszess Spritzenabszess NNP cord-015369-72cjogxz 353 7 waren waren NNP cord-015369-72cjogxz 353 8 Hepatitis Hepatitis NNP cord-015369-72cjogxz 353 9 C C NNP cord-015369-72cjogxz 353 10 positiv positiv JJ cord-015369-72cjogxz 353 11 , , , cord-015369-72cjogxz 353 12 3 3 CD cord-015369-72cjogxz 353 13 von von NNP cord-015369-72cjogxz 353 14 33 33 CD cord-015369-72cjogxz 353 15 Patienten Patienten NNP cord-015369-72cjogxz 353 16 HIV HIV NNP cord-015369-72cjogxz 353 17 Ipositiv Ipositiv NNP cord-015369-72cjogxz 353 18 . . . cord-015369-72cjogxz 354 1 Es Es NNP cord-015369-72cjogxz 354 2 wurden wurden NNP cord-015369-72cjogxz 354 3 bis bis NNP cord-015369-72cjogxz 354 4 zur zur NNP cord-015369-72cjogxz 354 5 vollen vollen NNP cord-015369-72cjogxz 354 6 Abheilung Abheilung NNP cord-015369-72cjogxz 354 7 bzw bzw NNP cord-015369-72cjogxz 354 8 . . . cord-015369-72cjogxz 355 1 Rekonstruktion rekonstruktion NN cord-015369-72cjogxz 355 2 insgesamt insgesamt NNP cord-015369-72cjogxz 355 3 224 224 CD cord-015369-72cjogxz 355 4 Operationen Operationen NNP cord-015369-72cjogxz 355 5 durchgefü durchgefü NNP cord-015369-72cjogxz 355 6 hrt hrt NNP cord-015369-72cjogxz 355 7 . . . cord-015369-72cjogxz 356 1 Dies Dies NNP cord-015369-72cjogxz 356 2 entsprach entsprach VBP cord-015369-72cjogxz 356 3 einer einer NNP cord-015369-72cjogxz 356 4 durchschnittlich durchschnittlich NNP cord-015369-72cjogxz 357 1 erforderlichen erforderlichen NNP cord-015369-72cjogxz 357 2 Op Op NNP cord-015369-72cjogxz 357 3 - - HYPH cord-015369-72cjogxz 357 4 Anzahl Anzahl NNP cord-015369-72cjogxz 357 5 von von NNP cord-015369-72cjogxz 357 6 1,25 1,25 CD cord-015369-72cjogxz 357 7 bei bei NNP cord-015369-72cjogxz 357 8 Panaritien Panaritien NNP cord-015369-72cjogxz 357 9 , , , cord-015369-72cjogxz 357 10 2,05 2,05 NNP cord-015369-72cjogxz 357 11 bei bei NNP cord-015369-72cjogxz 357 12 Phlegmonen Phlegmonen NNP cord-015369-72cjogxz 357 13 und und XX cord-015369-72cjogxz 357 14 2,09 2,09 CD cord-015369-72cjogxz 357 15 bei bei NNP cord-015369-72cjogxz 357 16 Spritzenabszessen Spritzenabszessen NNP cord-015369-72cjogxz 357 17 . . . cord-015369-72cjogxz 358 1 Die die VB cord-015369-72cjogxz 358 2 durchschnittliche durchschnittliche NNP cord-015369-72cjogxz 358 3 Aufenthaltsdauer Aufenthaltsdauer NNP cord-015369-72cjogxz 358 4 war war NN cord-015369-72cjogxz 358 5 mit mit NNP cord-015369-72cjogxz 359 1 8 8 CD cord-015369-72cjogxz 359 2 Tagen Tagen NNP cord-015369-72cjogxz 359 3 bei bei NNP cord-015369-72cjogxz 359 4 den den NNP cord-015369-72cjogxz 359 5 Panaritien Panaritien NNP cord-015369-72cjogxz 359 6 am be VBP cord-015369-72cjogxz 359 7 kürzesten kürzesten NNP cord-015369-72cjogxz 359 8 ( ( -LRB- cord-015369-72cjogxz 359 9 Phlegmone Phlegmone NNP cord-015369-72cjogxz 359 10 10 10 CD cord-015369-72cjogxz 359 11 Tage Tage NNP cord-015369-72cjogxz 359 12 , , , cord-015369-72cjogxz 359 13 Spritzenabszesse Spritzenabszesse NNP cord-015369-72cjogxz 359 14 13 13 CD cord-015369-72cjogxz 359 15 Tage Tage NNP cord-015369-72cjogxz 359 16 ) ) -RRB- cord-015369-72cjogxz 359 17 . . . cord-015369-72cjogxz 360 1 Insgesamt Insgesamt NNP cord-015369-72cjogxz 360 2 waren waren NNP cord-015369-72cjogxz 361 1 8 8 CD cord-015369-72cjogxz 361 2 Lappenplastiken Lappenplastiken NNP cord-015369-72cjogxz 361 3 und und IN cord-015369-72cjogxz 361 4 12 12 CD cord-015369-72cjogxz 361 5 Amputationen Amputationen NNP cord-015369-72cjogxz 361 6 notwendig notwendig NNP cord-015369-72cjogxz 361 7 . . . cord-015369-72cjogxz 362 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 362 2 . . . cord-015369-72cjogxz 363 1 An an DT cord-015369-72cjogxz 363 2 unserem unserem JJ cord-015369-72cjogxz 363 3 stark stark JJ cord-015369-72cjogxz 363 4 vorselektionierten vorselektionierten NNP cord-015369-72cjogxz 363 5 Krankengut Krankengut NNP cord-015369-72cjogxz 363 6 zeigte zeigte NNP cord-015369-72cjogxz 364 1 sich sich NNP cord-015369-72cjogxz 364 2 das das NNP cord-015369-72cjogxz 364 3 Panaritium Panaritium NNP cord-015369-72cjogxz 364 4 als als CD cord-015369-72cjogxz 364 5 die die VBP cord-015369-72cjogxz 365 1 häufigste häufigste NNP cord-015369-72cjogxz 365 2 Infektion Infektion NNP cord-015369-72cjogxz 366 1 an an DT cord-015369-72cjogxz 366 2 der der NNP cord-015369-72cjogxz 366 3 Hand Hand NNP cord-015369-72cjogxz 366 4 mit mit NNP cord-015369-72cjogxz 366 5 der der NNP cord-015369-72cjogxz 366 6 geringsten geringsten NNP cord-015369-72cjogxz 366 7 Anzahl Anzahl NNP cord-015369-72cjogxz 367 1 an an DT cord-015369-72cjogxz 367 2 notwendigen notwendigen NN cord-015369-72cjogxz 367 3 Eingriffen Eingriffen NNP cord-015369-72cjogxz 368 1 und und NNP cord-015369-72cjogxz 368 2 der der NNP cord-015369-72cjogxz 368 3 kürzesten kürzesten NNP cord-015369-72cjogxz 368 4 Aufenthaltsdauer Aufenthaltsdauer NNP cord-015369-72cjogxz 368 5 . . . cord-015369-72cjogxz 369 1 Phlegmone phlegmone NN cord-015369-72cjogxz 369 2 mussten mussten VBD cord-015369-72cjogxz 370 1 wegen wegen NNP cord-015369-72cjogxz 370 2 des des NNP cord-015369-72cjogxz 371 1 teilweise teilweise NNP cord-015369-72cjogxz 372 1 sehr sehr NNP cord-015369-72cjogxz 372 2 ausgedehnten ausgedehnten NNP cord-015369-72cjogxz 372 3 Befundes Befundes NNP cord-015369-72cjogxz 372 4 bis bis NNP cord-015369-72cjogxz 372 5 zu zu NNP cord-015369-72cjogxz 372 6 5x 5x NNP cord-015369-72cjogxz 372 7 operiert operiert NNP cord-015369-72cjogxz 372 8 werden werden NNP cord-015369-72cjogxz 372 9 . . . cord-015369-72cjogxz 373 1 Durchschnittlich Durchschnittlich NNP cord-015369-72cjogxz 373 2 sind sind NNP cord-015369-72cjogxz 373 3 2 2 CD cord-015369-72cjogxz 374 1 Operationen Operationen NNP cord-015369-72cjogxz 374 2 bis bis NNP cord-015369-72cjogxz 374 3 zur zur NNP cord-015369-72cjogxz 374 4 völligen völligen NNP cord-015369-72cjogxz 374 5 Abheilung Abheilung NNP cord-015369-72cjogxz 374 6 bzw bzw NNP cord-015369-72cjogxz 374 7 . . . cord-015369-72cjogxz 375 1 Rekonstruktion rekonstruktion NN cord-015369-72cjogxz 375 2 nötig nötig NN cord-015369-72cjogxz 375 3 . . . cord-015369-72cjogxz 376 1 In in IN cord-015369-72cjogxz 376 2 der der NNP cord-015369-72cjogxz 376 3 Gruppe Gruppe NNP cord-015369-72cjogxz 376 4 der der NNP cord-015369-72cjogxz 376 5 Spritzenabszesse Spritzenabszesse NNP cord-015369-72cjogxz 376 6 fanden fanden NNP cord-015369-72cjogxz 376 7 sich sich NNP cord-015369-72cjogxz 376 8 in in IN cord-015369-72cjogxz 376 9 33 33 CD cord-015369-72cjogxz 376 10 % % NN cord-015369-72cjogxz 376 11 Staphylokokken Staphylokokken NNP cord-015369-72cjogxz 376 12 , , , cord-015369-72cjogxz 376 13 40 40 CD cord-015369-72cjogxz 376 14 % % NN cord-015369-72cjogxz 376 15 Streptokokken Streptokokken NNP cord-015369-72cjogxz 376 16 , , , cord-015369-72cjogxz 376 17 9 9 CD cord-015369-72cjogxz 376 18 % % NN cord-015369-72cjogxz 376 19 andere andere NNS cord-015369-72cjogxz 376 20 grampositive grampositive NN cord-015369-72cjogxz 376 21 und und IN cord-015369-72cjogxz 376 22 gramnegative gramnegative NNP cord-015369-72cjogxz 376 23 Keime Keime NNP cord-015369-72cjogxz 376 24 , , , cord-015369-72cjogxz 376 25 3 3 CD cord-015369-72cjogxz 376 26 % % NN cord-015369-72cjogxz 376 27 Anaerobier Anaerobier NNP cord-015369-72cjogxz 376 28 , , , cord-015369-72cjogxz 377 1 18,2 18,2 CD cord-015369-72cjogxz 377 2 % % NN cord-015369-72cjogxz 377 3 Mischflora Mischflora NNP cord-015369-72cjogxz 377 4 und und IN cord-015369-72cjogxz 377 5 in in IN cord-015369-72cjogxz 377 6 25 25 CD cord-015369-72cjogxz 377 7 % % NN cord-015369-72cjogxz 377 8 kein kein NNP cord-015369-72cjogxz 377 9 Wachstum Wachstum NNP cord-015369-72cjogxz 377 10 . . . cord-015369-72cjogxz 378 1 In in IN cord-015369-72cjogxz 378 2 der der NNP cord-015369-72cjogxz 378 3 Gruppe Gruppe NNP cord-015369-72cjogxz 378 4 der der NNP cord-015369-72cjogxz 378 5 Phlegmonen Phlegmonen NNP cord-015369-72cjogxz 378 6 fanden fanden NNP cord-015369-72cjogxz 378 7 sich sich NNP cord-015369-72cjogxz 378 8 in in IN cord-015369-72cjogxz 378 9 53 53 CD cord-015369-72cjogxz 378 10 % % NN cord-015369-72cjogxz 378 11 Staphylokokken Staphylokokken NNP cord-015369-72cjogxz 378 12 , , , cord-015369-72cjogxz 378 13 in in IN cord-015369-72cjogxz 378 14 12 12 CD cord-015369-72cjogxz 378 15 % % NN cord-015369-72cjogxz 378 16 Streptokokken Streptokokken NNP cord-015369-72cjogxz 378 17 , , , cord-015369-72cjogxz 378 18 in in IN cord-015369-72cjogxz 378 19 20 20 CD cord-015369-72cjogxz 378 20 % % NN cord-015369-72cjogxz 378 21 andere andere NNS cord-015369-72cjogxz 378 22 grampositive grampositive NN cord-015369-72cjogxz 378 23 und und IN cord-015369-72cjogxz 378 24 gramnegative gramnegative NNP cord-015369-72cjogxz 378 25 Keime Keime NNP cord-015369-72cjogxz 378 26 , , , cord-015369-72cjogxz 378 27 in in IN cord-015369-72cjogxz 378 28 15 15 CD cord-015369-72cjogxz 378 29 % % NN cord-015369-72cjogxz 378 30 fand fand NN cord-015369-72cjogxz 378 31 sich sich NNP cord-015369-72cjogxz 378 32 Mischflora Mischflora NNP cord-015369-72cjogxz 378 33 und und IN cord-015369-72cjogxz 378 34 in in IN cord-015369-72cjogxz 378 35 15 15 CD cord-015369-72cjogxz 378 36 % % NN cord-015369-72cjogxz 378 37 zeigte zeigte NN cord-015369-72cjogxz 379 1 sich sich NNP cord-015369-72cjogxz 379 2 kein kein NNP cord-015369-72cjogxz 379 3 Wachstum Wachstum NNP cord-015369-72cjogxz 379 4 . . . cord-015369-72cjogxz 380 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 380 2 . . . cord-015369-72cjogxz 381 1 Die die VB cord-015369-72cjogxz 382 1 Kenntnis Kenntnis NNP cord-015369-72cjogxz 382 2 des des NNP cord-015369-72cjogxz 382 3 Keimspektrums Keimspektrums NNP cord-015369-72cjogxz 382 4 ermöglicht ermöglicht NNP cord-015369-72cjogxz 383 1 eine eine NNP cord-015369-72cjogxz 383 2 adäquate adäquate NNP cord-015369-72cjogxz 383 3 kalkulierte kalkulierte NNP cord-015369-72cjogxz 384 1 Therapie Therapie NNP cord-015369-72cjogxz 384 2 bis bis NN cord-015369-72cjogxz 384 3 zum zum NNP cord-015369-72cjogxz 384 4 Eintreffen Eintreffen NNP cord-015369-72cjogxz 384 5 des des FW cord-015369-72cjogxz 384 6 Abstrichergebnisses Abstrichergebnisses NNP cord-015369-72cjogxz 384 7 . . . cord-015369-72cjogxz 385 1 I -PRON- PRP cord-015369-72cjogxz 385 2 m be VBP cord-015369-72cjogxz 385 3 Rahmen Rahmen NNP cord-015369-72cjogxz 385 4 unserer unserer JJ cord-015369-72cjogxz 385 5 Untersuchungen Untersuchungen NNP cord-015369-72cjogxz 385 6 zeigten zeigten XX cord-015369-72cjogxz 385 7 sich sich NNP cord-015369-72cjogxz 385 8 deutliche deutliche NNP cord-015369-72cjogxz 385 9 Unterschiede Unterschiede NNP cord-015369-72cjogxz 386 1 zwischen zwischen NNP cord-015369-72cjogxz 386 2 den den NNP cord-015369-72cjogxz 386 3 Keimspektren Keimspektren NNP cord-015369-72cjogxz 386 4 von von NNP cord-015369-72cjogxz 386 5 Patienten Patienten NNP cord-015369-72cjogxz 386 6 mit mit NNP cord-015369-72cjogxz 386 7 Panaritien Panaritien NNP cord-015369-72cjogxz 386 8 , , , cord-015369-72cjogxz 386 9 Phlegmonen Phlegmonen NNP cord-015369-72cjogxz 386 10 und und IN cord-015369-72cjogxz 386 11 Spritzenabszessen Spritzenabszessen NNP cord-015369-72cjogxz 386 12 . . . cord-015369-72cjogxz 387 1 Diese Diese NNP cord-015369-72cjogxz 387 2 Erkenntnis Erkenntnis NNP cord-015369-72cjogxz 387 3 sollte sollte NNP cord-015369-72cjogxz 387 4 bei bei NNP cord-015369-72cjogxz 387 5 der der NNP cord-015369-72cjogxz 387 6 Wahl Wahl NNP cord-015369-72cjogxz 387 7 des des FW cord-015369-72cjogxz 387 8 geeigneten geeigneten NNP cord-015369-72cjogxz 387 9 Antibiotikums Antibiotikums NNP cord-015369-72cjogxz 387 10 Berücksichtigung Berücksichtigung NNP cord-015369-72cjogxz 387 11 finden finden NNP cord-015369-72cjogxz 387 12 . . . cord-015369-72cjogxz 388 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 388 2 . . . cord-015369-72cjogxz 389 1 Grundprinzip Grundprinzip NNP cord-015369-72cjogxz 389 2 der der NNP cord-015369-72cjogxz 389 3 plastisch plastisch NNP cord-015369-72cjogxz 389 4 - - HYPH cord-015369-72cjogxz 389 5 chirurgischen chirurgischen NNP cord-015369-72cjogxz 390 1 Infektchirurgie Infektchirurgie NNP cord-015369-72cjogxz 390 2 ist ist NNP cord-015369-72cjogxz 391 1 seit seit NNP cord-015369-72cjogxz 391 2 jeher jeher NNP cord-015369-72cjogxz 391 3 das das NNP cord-015369-72cjogxz 391 4 radikale radikale NNP cord-015369-72cjogxz 391 5 chirurgische chirurgische NNP cord-015369-72cjogxz 391 6 Debridement Debridement NNP cord-015369-72cjogxz 391 7 , , , cord-015369-72cjogxz 391 8 gefolgt gefolgt NNP cord-015369-72cjogxz 391 9 von von NNP cord-015369-72cjogxz 391 10 anfänglicher anfänglicher NNP cord-015369-72cjogxz 391 11 offener offener NNP cord-015369-72cjogxz 391 12 Wundbehandlung Wundbehandlung NNP cord-015369-72cjogxz 391 13 . . . cord-015369-72cjogxz 392 1 Seit Seit NNP cord-015369-72cjogxz 392 2 Jahren Jahren NNP cord-015369-72cjogxz 392 3 kommt kommt NNP cord-015369-72cjogxz 392 4 das das NNP cord-015369-72cjogxz 392 5 V.A.C.-System V.A.C.-System NNP cord-015369-72cjogxz 392 6 zur zur NNP cord-015369-72cjogxz 392 7 Wundkonditionierung Wundkonditionierung NNP cord-015369-72cjogxz 392 8 erfolgreich erfolgreich RB cord-015369-72cjogxz 392 9 zur zur NNP cord-015369-72cjogxz 392 10 Anwendung Anwendung NNP cord-015369-72cjogxz 392 11 . . . cord-015369-72cjogxz 393 1 Der Der NNP cord-015369-72cjogxz 393 2 Defektverschluß Defektverschluß NNP cord-015369-72cjogxz 393 3 erfolgt erfolgt NNP cord-015369-72cjogxz 393 4 erst erst FW cord-015369-72cjogxz 393 5 bei bei NNP cord-015369-72cjogxz 393 6 Beherrschung Beherrschung NNP cord-015369-72cjogxz 393 7 des des NNP cord-015369-72cjogxz 393 8 Infektes Infektes NNP cord-015369-72cjogxz 393 9 durch durch NNP cord-015369-72cjogxz 393 10 Auffüllung Auffüllung NNP cord-015369-72cjogxz 393 11 des des NNP cord-015369-72cjogxz 393 12 Totraumes Totraumes NNP cord-015369-72cjogxz 394 1 durch durch NNP cord-015369-72cjogxz 394 2 gut gut NNP cord-015369-72cjogxz 394 3 durchblutetes durchblutete NNS cord-015369-72cjogxz 395 1 Gewebe Gewebe NNP cord-015369-72cjogxz 395 2 , , , cord-015369-72cjogxz 395 3 meist meist NNP cord-015369-72cjogxz 395 4 Lappenplastiken Lappenplastiken NNP cord-015369-72cjogxz 395 5 , , , cord-015369-72cjogxz 395 6 bei bei NNP cord-015369-72cjogxz 395 7 reiner reiner NNP cord-015369-72cjogxz 395 8 Weichteilbeteiligung Weichteilbeteiligung NNP cord-015369-72cjogxz 395 9 auch auch NNP cord-015369-72cjogxz 395 10 durch durch NNP cord-015369-72cjogxz 395 11 einfache einfache JJ cord-015369-72cjogxz 395 12 Spalthauttransplantate Spalthauttransplantate NNP cord-015369-72cjogxz 395 13 . . . cord-015369-72cjogxz 396 1 Problematisch Problematisch NNP cord-015369-72cjogxz 396 2 wird wird NNP cord-015369-72cjogxz 396 3 es es NNP cord-015369-72cjogxz 396 4 , , , cord-015369-72cjogxz 396 5 wenn wenn NNP cord-015369-72cjogxz 396 6 aufgrund aufgrund NNP cord-015369-72cjogxz 396 7 der der NNP cord-015369-72cjogxz 396 8 anatomischen anatomischen NNP cord-015369-72cjogxz 396 9 Situation situation NN cord-015369-72cjogxz 396 10 ein ein NN cord-015369-72cjogxz 396 11 radikales radikale VBZ cord-015369-72cjogxz 396 12 Debridement debridement JJ cord-015369-72cjogxz 396 13 nur nur RB cord-015369-72cjogxz 396 14 bedingt bedingt JJ cord-015369-72cjogxz 396 15 möglich möglich NNP cord-015369-72cjogxz 396 16 ist ist NN cord-015369-72cjogxz 396 17 bzw bzw NNP cord-015369-72cjogxz 396 18 . . . cord-015369-72cjogxz 397 1 eine eine NNP cord-015369-72cjogxz 397 2 Keimpersistenz Keimpersistenz NNP cord-015369-72cjogxz 397 3 zu zu NNP cord-015369-72cjogxz 397 4 erwarten erwarten NNP cord-015369-72cjogxz 397 5 ist ist NNP cord-015369-72cjogxz 397 6 . . . cord-015369-72cjogxz 398 1 Methodik Methodik NNP cord-015369-72cjogxz 398 2 . . . cord-015369-72cjogxz 399 1 Das Das NNP cord-015369-72cjogxz 399 2 V.A.C.-Instill V.A.C.-Instill NNP cord-015369-72cjogxz 399 3 + + CC cord-015369-72cjogxz 399 4 ermöglicht ermöglicht FW cord-015369-72cjogxz 399 5 ein ein NNP cord-015369-72cjogxz 399 6 3-Stufenprogramm 3-Stufenprogramm NNP cord-015369-72cjogxz 399 7 : : : cord-015369-72cjogxz 400 1 Instillation instillation NN cord-015369-72cjogxz 400 2 -Einwirkzeit -Einwirkzeit NNP cord-015369-72cjogxz 401 1 -Vakuumtherapie -Vakuumtherapie NNP cord-015369-72cjogxz 401 2 kommen kommen NNP cord-015369-72cjogxz 401 3 zyklusartig zyklusartig NNP cord-015369-72cjogxz 401 4 zur zur NNP cord-015369-72cjogxz 401 5 Anwendung Anwendung NNP cord-015369-72cjogxz 401 6 . . . cord-015369-72cjogxz 402 1 Bei Bei NNP cord-015369-72cjogxz 402 2 unseren unseren NNP cord-015369-72cjogxz 403 1 Patienten Patienten NNP cord-015369-72cjogxz 403 2 kam kam NNP cord-015369-72cjogxz 404 1 ausschließlich ausschließlich NNP cord-015369-72cjogxz 404 2 ein ein NNP cord-015369-72cjogxz 404 3 lokales lokales NNP cord-015369-72cjogxz 404 4 Antiseptikum Antiseptikum NNP cord-015369-72cjogxz 404 5 zur zur NNP cord-015369-72cjogxz 404 6 Anwendung Anwendung NNP cord-015369-72cjogxz 404 7 . . . cord-015369-72cjogxz 405 1 Das Das NNP cord-015369-72cjogxz 405 2 Patientengut Patientengut NNP cord-015369-72cjogxz 405 3 hatte hatte NNP cord-015369-72cjogxz 405 4 eines eines FW cord-015369-72cjogxz 405 5 gemeinsam gemeinsam NNP cord-015369-72cjogxz 405 6 : : : cord-015369-72cjogxz 406 1 Debridement Debridement NNP cord-015369-72cjogxz 406 2 und und IN cord-015369-72cjogxz 406 3 geplante geplante NNP cord-015369-72cjogxz 406 4 Defektdeckung Defektdeckung NNP cord-015369-72cjogxz 406 5 schienen schienen NNP cord-015369-72cjogxz 406 6 für für NNP cord-015369-72cjogxz 406 7 eine eine NNP cord-015369-72cjogxz 406 8 Infektsanierung Infektsanierung NNP cord-015369-72cjogxz 406 9 unzureichend unzureichend NNP cord-015369-72cjogxz 406 10 . . . cord-015369-72cjogxz 407 1 Wir Wir NNP cord-015369-72cjogxz 407 2 berichten berichten NNP cord-015369-72cjogxz 407 3 über über NNP cord-015369-72cjogxz 408 1 2 2 LS cord-015369-72cjogxz 408 2 Patienten Patienten NNP cord-015369-72cjogxz 408 3 , , , cord-015369-72cjogxz 408 4 die die VB cord-015369-72cjogxz 408 5 wegen wegen NNP cord-015369-72cjogxz 408 6 hämatogenem hämatogenem NNP cord-015369-72cjogxz 408 7 Handgelenksempyem Handgelenksempyem NNP cord-015369-72cjogxz 408 8 mit mit NNP cord-015369-72cjogxz 408 9 Beteiligung Beteiligung NNP cord-015369-72cjogxz 408 10 aller aller NNP cord-015369-72cjogxz 408 11 Handwurzelknochen Handwurzelknochen NNP cord-015369-72cjogxz 408 12 an an DT cord-015369-72cjogxz 408 13 unserer unserer JJ cord-015369-72cjogxz 408 14 Abteilung Abteilung NNP cord-015369-72cjogxz 408 15 in in IN cord-015369-72cjogxz 408 16 Behandlung Behandlung NNP cord-015369-72cjogxz 408 17 waren waren NNP cord-015369-72cjogxz 408 18 . . . cord-015369-72cjogxz 409 1 Zur Zur NNP cord-015369-72cjogxz 409 2 Anwendung Anwendung NNP cord-015369-72cjogxz 409 3 kam kam NNP cord-015369-72cjogxz 409 4 der der NNP cord-015369-72cjogxz 409 5 Polyvinylalkoholschwamm Polyvinylalkoholschwamm NNP cord-015369-72cjogxz 409 6 . . . cord-015369-72cjogxz 410 1 Die die VB cord-015369-72cjogxz 410 2 Instillationsdauer Instillationsdauer NNP cord-015369-72cjogxz 410 3 war war NN cord-015369-72cjogxz 410 4 unmittelbar unmittelbar NN cord-015369-72cjogxz 410 5 von von NNP cord-015369-72cjogxz 410 6 der der NNP cord-015369-72cjogxz 410 7 Wundgröße Wundgröße NNP cord-015369-72cjogxz 410 8 abhängig abhängig NNS cord-015369-72cjogxz 410 9 . . . cord-015369-72cjogxz 411 1 Die die VB cord-015369-72cjogxz 411 2 Therapiedauer Therapiedauer NNP cord-015369-72cjogxz 411 3 betrug betrug NNP cord-015369-72cjogxz 411 4 maximal maximal JJ cord-015369-72cjogxz 411 5 1o 1o CD cord-015369-72cjogxz 411 6 Tage Tage NNP cord-015369-72cjogxz 411 7 , , , cord-015369-72cjogxz 411 8 der der NN cord-015369-72cjogxz 411 9 V V NNP cord-015369-72cjogxz 411 10 , , , cord-015369-72cjogxz 411 11 A A NNP cord-015369-72cjogxz 411 12 , , , cord-015369-72cjogxz 411 13 C,-Wechsel C,-Wechsel NNP cord-015369-72cjogxz 411 14 wurde wurde NNP cord-015369-72cjogxz 411 15 drei drei NNP cord-015369-72cjogxz 411 16 - - HYPH cord-015369-72cjogxz 411 17 bis bis NNP cord-015369-72cjogxz 411 18 viertägig viertägig NNS cord-015369-72cjogxz 411 19 durchgeführt durchgeführt NN cord-015369-72cjogxz 411 20 . . . cord-015369-72cjogxz 412 1 Die die VB cord-015369-72cjogxz 413 1 Defektdeckung Defektdeckung NNP cord-015369-72cjogxz 413 2 erfolgte erfolgte NN cord-015369-72cjogxz 414 1 durch durch NNP cord-015369-72cjogxz 414 2 lokale lokale NNP cord-015369-72cjogxz 414 3 oder oder NNP cord-015369-72cjogxz 414 4 gestielte gestielte NNP cord-015369-72cjogxz 414 5 Lappenplastiken Lappenplastiken NNP cord-015369-72cjogxz 414 6 . . . cord-015369-72cjogxz 415 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 415 2 . . . cord-015369-72cjogxz 416 1 In in IN cord-015369-72cjogxz 416 2 allen allen NNP cord-015369-72cjogxz 416 3 Fällen Fällen NNP cord-015369-72cjogxz 416 4 konnte konnte NNP cord-015369-72cjogxz 416 5 trotz trotz NNP cord-015369-72cjogxz 416 6 eingeschränkter eingeschränkter NNP cord-015369-72cjogxz 416 7 Radikalität Radikalität NNP cord-015369-72cjogxz 416 8 eines eines NNP cord-015369-72cjogxz 416 9 chirurgischen chirurgischen NNP cord-015369-72cjogxz 416 10 Debridements Debridements NNP cord-015369-72cjogxz 416 11 eine eine NNP cord-015369-72cjogxz 416 12 Infektsanierung Infektsanierung NNP cord-015369-72cjogxz 416 13 erzielt erzielt NNS cord-015369-72cjogxz 416 14 werden werden NNP cord-015369-72cjogxz 416 15 . . . cord-015369-72cjogxz 417 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 417 2 . . . cord-015369-72cjogxz 418 1 Das Das NNP cord-015369-72cjogxz 418 2 V.A.C.-Instill V.A.C.-Instill NNP cord-015369-72cjogxz 418 3 + + CC cord-015369-72cjogxz 418 4 stellt stellt NNP cord-015369-72cjogxz 419 1 für für NNP cord-015369-72cjogxz 419 2 uns uns NNP cord-015369-72cjogxz 419 3 ein ein NNP cord-015369-72cjogxz 419 4 wertvolles wertvolle NNS cord-015369-72cjogxz 419 5 Instrument Instrument NNP cord-015369-72cjogxz 419 6 zur zur NNP cord-015369-72cjogxz 419 7 Infektsanierung Infektsanierung NNP cord-015369-72cjogxz 419 8 in in IN cord-015369-72cjogxz 419 9 anatomisch anatomisch NNP cord-015369-72cjogxz 419 10 problematischen problematischen NNP cord-015369-72cjogxz 419 11 Zonen Zonen NNP cord-015369-72cjogxz 420 1 und und IN cord-015369-72cjogxz 420 2 eingeschränkter eingeschränkter RB cord-015369-72cjogxz 421 1 Möglichkeit Möglichkeit NNP cord-015369-72cjogxz 421 2 eines eine NNS cord-015369-72cjogxz 422 1 radikalen radikalen NNP cord-015369-72cjogxz 422 2 chirurgischen chirurgischen NNP cord-015369-72cjogxz 422 3 Debridements Debridements NNP cord-015369-72cjogxz 422 4 dar dar NNP cord-015369-72cjogxz 422 5 . . . cord-015369-72cjogxz 423 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 423 2 . . . cord-015369-72cjogxz 424 1 Handinfektionen Handinfektionen NNP cord-015369-72cjogxz 424 2 wie wie NNP cord-015369-72cjogxz 424 3 Panaritien Panaritien NNP cord-015369-72cjogxz 424 4 und und IN cord-015369-72cjogxz 424 5 Phlegmone Phlegmone NNP cord-015369-72cjogxz 424 6 stellen stellen XX cord-015369-72cjogxz 424 7 eine eine NNP cord-015369-72cjogxz 424 8 große große NNP cord-015369-72cjogxz 424 9 Gefahr Gefahr NNP cord-015369-72cjogxz 424 10 fü fü IN cord-015369-72cjogxz 425 1 r r LS cord-015369-72cjogxz 425 2 die die VB cord-015369-72cjogxz 426 1 Integrität Integrität NNP cord-015369-72cjogxz 426 2 der der NNP cord-015369-72cjogxz 426 3 Hand Hand NNP cord-015369-72cjogxz 426 4 dar dar NNP cord-015369-72cjogxz 426 5 . . . cord-015369-72cjogxz 427 1 Der Der NNP cord-015369-72cjogxz 427 2 Schritt Schritt NNP cord-015369-72cjogxz 427 3 zur zur NNP cord-015369-72cjogxz 427 4 chirurgischen chirurgischen NNP cord-015369-72cjogxz 428 1 Sanierung Sanierung NNP cord-015369-72cjogxz 428 2 muss muss NNP cord-015369-72cjogxz 429 1 sorgfältig sorgfältig NNP cord-015369-72cjogxz 429 2 gestellt gestellt NNP cord-015369-72cjogxz 429 3 werden werden NNP cord-015369-72cjogxz 429 4 und und NNP cord-015369-72cjogxz 429 5 richtet richtet NNP cord-015369-72cjogxz 429 6 sich sich NNP cord-015369-72cjogxz 430 1 nach nach NNP cord-015369-72cjogxz 430 2 klinischen klinischen NNP cord-015369-72cjogxz 431 1 sowie sowie NNP cord-015369-72cjogxz 431 2 radiologischen radiologischen NNP cord-015369-72cjogxz 431 3 Gesichtspunkten Gesichtspunkten NNP cord-015369-72cjogxz 431 4 . . . cord-015369-72cjogxz 432 1 Trotz Trotz NNP cord-015369-72cjogxz 432 2 hohen hohen NNP cord-015369-72cjogxz 432 3 Inzidenzen Inzidenzen NNP cord-015369-72cjogxz 432 4 sind sind VBP cord-015369-72cjogxz 432 5 nur nur NNP cord-015369-72cjogxz 432 6 wenige wenige JJ cord-015369-72cjogxz 432 7 Daten Daten NNP cord-015369-72cjogxz 432 8 zum zum NNP cord-015369-72cjogxz 433 1 Langzeitoutcome Langzeitoutcome NNP cord-015369-72cjogxz 433 2 von von NNP cord-015369-72cjogxz 434 1 chirurgischen chirurgischen NNP cord-015369-72cjogxz 434 2 Eingriffen Eingriffen NNP cord-015369-72cjogxz 435 1 bezü bezü NNP cord-015369-72cjogxz 435 2 glich glich NNP cord-015369-72cjogxz 435 3 der der NNP cord-015369-72cjogxz 435 4 verbleibenden verbleibenden NNP cord-015369-72cjogxz 435 5 Funktionalität Funktionalität NNP cord-015369-72cjogxz 435 6 der der NNP cord-015369-72cjogxz 435 7 Hand Hand NNP cord-015369-72cjogxz 435 8 vorhanden vorhanden NN cord-015369-72cjogxz 435 9 . . . cord-015369-72cjogxz 436 1 Methodik Methodik NNP cord-015369-72cjogxz 436 2 . . . cord-015369-72cjogxz 437 1 Um um UH cord-015369-72cjogxz 438 1 das das NNP cord-015369-72cjogxz 438 2 effektive effektive NNP cord-015369-72cjogxz 438 3 Outcome Outcome NNP cord-015369-72cjogxz 438 4 von von NNP cord-015369-72cjogxz 438 5 solchen solchen NNP cord-015369-72cjogxz 439 1 Eingriffen Eingriffen NNP cord-015369-72cjogxz 439 2 evaluieren evaluieren NN cord-015369-72cjogxz 440 1 zu zu NNP cord-015369-72cjogxz 440 2 können können NNP cord-015369-72cjogxz 440 3 wurden wurden VBD cord-015369-72cjogxz 440 4 alle alle NNP cord-015369-72cjogxz 440 5 Patienten Patienten NNP cord-015369-72cjogxz 440 6 chirurgisch chirurgisch JJ cord-015369-72cjogxz 440 7 sanierter sanierter NN cord-015369-72cjogxz 440 8 Handinfektionen Handinfektionen NNP cord-015369-72cjogxz 440 9 an an DT cord-015369-72cjogxz 440 10 unserer unserer JJ cord-015369-72cjogxz 440 11 Abteilung Abteilung NNP cord-015369-72cjogxz 440 12 i -PRON- PRP cord-015369-72cjogxz 440 13 m be VBP cord-015369-72cjogxz 440 14 Zeitraum Zeitraum NNP cord-015369-72cjogxz 440 15 von von NNP cord-015369-72cjogxz 440 16 2002 2002 CD cord-015369-72cjogxz 440 17 - - SYM cord-015369-72cjogxz 440 18 2008 2008 CD cord-015369-72cjogxz 441 1 erhoben erhoben NNP cord-015369-72cjogxz 441 2 und und NNP cord-015369-72cjogxz 442 1 anschließend anschließend NNP cord-015369-72cjogxz 442 2 zu zu NNP cord-015369-72cjogxz 442 3 einer einer NNP cord-015369-72cjogxz 442 4 Nachuntersuchung Nachuntersuchung NNP cord-015369-72cjogxz 442 5 eingeladen eingeladen NNP cord-015369-72cjogxz 442 6 . . . cord-015369-72cjogxz 443 1 I -PRON- PRP cord-015369-72cjogxz 443 2 m be VBP cord-015369-72cjogxz 443 3 Rahmen Rahmen NNP cord-015369-72cjogxz 443 4 der der NNP cord-015369-72cjogxz 443 5 Nachuntersuchung Nachuntersuchung NNP cord-015369-72cjogxz 443 6 wurden wurden CD cord-015369-72cjogxz 443 7 Sensibilität Sensibilität NNP cord-015369-72cjogxz 443 8 , , , cord-015369-72cjogxz 443 9 Kraft Kraft NNP cord-015369-72cjogxz 443 10 und und IN cord-015369-72cjogxz 443 11 Bewegungsumfang Bewegungsumfang NNP cord-015369-72cjogxz 443 12 der der NNP cord-015369-72cjogxz 443 13 betroffenen betroffenen NNP cord-015369-72cjogxz 443 14 Extremität Extremität NNP cord-015369-72cjogxz 443 15 untersucht untersucht NN cord-015369-72cjogxz 443 16 . . . cord-015369-72cjogxz 444 1 Mittels Mittels NNP cord-015369-72cjogxz 444 2 eines eines NNP cord-015369-72cjogxz 444 3 Fragebogens Fragebogens NNP cord-015369-72cjogxz 444 4 wurden wurden VBD cord-015369-72cjogxz 444 5 subjektive subjektive NNP cord-015369-72cjogxz 444 6 Parameter Parameter NNP cord-015369-72cjogxz 444 7 bezüglich bezüglich NNP cord-015369-72cjogxz 444 8 der der NNP cord-015369-72cjogxz 444 9 betroffenen betroffenen NNP cord-015369-72cjogxz 444 10 Region Region NNP cord-015369-72cjogxz 444 11 dokumentiert dokumentiert NNP cord-015369-72cjogxz 444 12 . . . cord-015369-72cjogxz 445 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 445 2 . . . cord-015369-72cjogxz 446 1 Von Von NNP cord-015369-72cjogxz 446 2 den den NNP cord-015369-72cjogxz 447 1 49 49 CD cord-015369-72cjogxz 447 2 ausgehobenen ausgehobenen NNP cord-015369-72cjogxz 447 3 Patienten Patienten NNP cord-015369-72cjogxz 447 4 erschienen erschienen NNP cord-015369-72cjogxz 448 1 20 20 CD cord-015369-72cjogxz 448 2 Patienten Patienten NNP cord-015369-72cjogxz 448 3 ( ( -LRB- cord-015369-72cjogxz 448 4 41 41 CD cord-015369-72cjogxz 448 5 % % NN cord-015369-72cjogxz 448 6 ) ) -RRB- cord-015369-72cjogxz 448 7 zur zur NNP cord-015369-72cjogxz 448 8 Nachuntersuchung Nachuntersuchung NNP cord-015369-72cjogxz 448 9 . . . cord-015369-72cjogxz 449 1 Die die VB cord-015369-72cjogxz 449 2 durchschnittliche durchschnittliche NNP cord-015369-72cjogxz 449 3 Patientenzufriedenheit Patientenzufriedenheit NNP cord-015369-72cjogxz 449 4 auf auf NNP cord-015369-72cjogxz 449 5 einer einer NNP cord-015369-72cjogxz 449 6 Skala Skala NNP cord-015369-72cjogxz 449 7 von von NNP cord-015369-72cjogxz 449 8 1 1 CD cord-015369-72cjogxz 449 9 - - SYM cord-015369-72cjogxz 449 10 5 5 CD cord-015369-72cjogxz 449 11 lag lag NN cord-015369-72cjogxz 449 12 bei bei NNP cord-015369-72cjogxz 449 13 1,7 1,7 CD cord-015369-72cjogxz 449 14 , , , cord-015369-72cjogxz 449 15 eine eine NNP cord-015369-72cjogxz 449 16 deutliche deutliche NNP cord-015369-72cjogxz 449 17 Einschränkung Einschränkung NNP cord-015369-72cjogxz 449 18 der der NNP cord-015369-72cjogxz 449 19 Bewegungsfreiheit Bewegungsfreiheit NNP cord-015369-72cjogxz 449 20 war war NN cord-015369-72cjogxz 449 21 nur nur NN cord-015369-72cjogxz 449 22 bei bei NNP cord-015369-72cjogxz 449 23 2 2 CD cord-015369-72cjogxz 449 24 Patienten Patienten NNP cord-015369-72cjogxz 449 25 evaluierbar evaluierbar NN cord-015369-72cjogxz 449 26 ( ( -LRB- cord-015369-72cjogxz 449 27 18 18 CD cord-015369-72cjogxz 449 28 % % NN cord-015369-72cjogxz 449 29 ) ) -RRB- cord-015369-72cjogxz 449 30 . . . cord-015369-72cjogxz 450 1 Eine Eine NNP cord-015369-72cjogxz 450 2 objektivierbare objektivierbare NN cord-015369-72cjogxz 450 3 Bewegungseinschränkung Bewegungseinschränkung NNP cord-015369-72cjogxz 450 4 ging ging NNP cord-015369-72cjogxz 450 5 stets stet NNS cord-015369-72cjogxz 450 6 mit mit NNP cord-015369-72cjogxz 450 7 einer einer NNP cord-015369-72cjogxz 450 8 Verminderung Verminderung NNP cord-015369-72cjogxz 450 9 der der NNP cord-015369-72cjogxz 450 10 Kraft Kraft NNP cord-015369-72cjogxz 450 11 , , , cord-015369-72cjogxz 450 12 sowie sowie NNP cord-015369-72cjogxz 450 13 Sensibilitätsstörungen Sensibilitätsstörungen NNP cord-015369-72cjogxz 450 14 i -PRON- PRP cord-015369-72cjogxz 450 15 m be VBP cord-015369-72cjogxz 450 16 Bereich Bereich NNP cord-015369-72cjogxz 450 17 der der NNP cord-015369-72cjogxz 450 18 Finger Finger NNP cord-015369-72cjogxz 450 19 einher einher NN cord-015369-72cjogxz 450 20 . . . cord-015369-72cjogxz 451 1 Generell Generell NNP cord-015369-72cjogxz 451 2 kann kann NNP cord-015369-72cjogxz 451 3 gesagt gesagt NNP cord-015369-72cjogxz 452 1 werden werden NNP cord-015369-72cjogxz 452 2 , , , cord-015369-72cjogxz 452 3 dass dass NNP cord-015369-72cjogxz 452 4 eine eine NNP cord-015369-72cjogxz 452 5 weit weit NNP cord-015369-72cjogxz 452 6 fortgeschrittene fortgeschrittene NNP cord-015369-72cjogxz 452 7 Entzündung Entzündung NNP cord-015369-72cjogxz 452 8 , , , cord-015369-72cjogxz 452 9 die die VB cord-015369-72cjogxz 452 10 meist meist NNP cord-015369-72cjogxz 452 11 durch durch NNP cord-015369-72cjogxz 452 12 Zuwarten Zuwarten NNP cord-015369-72cjogxz 452 13 der der NNP cord-015369-72cjogxz 452 14 Patienten Patienten NNP cord-015369-72cjogxz 452 15 zustande zustande NNP cord-015369-72cjogxz 452 16 kam kam NNP cord-015369-72cjogxz 452 17 , , , cord-015369-72cjogxz 452 18 das das NNP cord-015369-72cjogxz 452 19 Outcome Outcome NNP cord-015369-72cjogxz 452 20 verschlechtert verschlechtert NN cord-015369-72cjogxz 452 21 . . . cord-015369-72cjogxz 453 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 453 2 . . . cord-015369-72cjogxz 454 1 Je Je NNP cord-015369-72cjogxz 455 1 nach nach NNP cord-015369-72cjogxz 455 2 Ausprägung Ausprägung NNP cord-015369-72cjogxz 455 3 zeigt zeigt NNP cord-015369-72cjogxz 455 4 sich sich NNP cord-015369-72cjogxz 455 5 einerseits einerseit VBZ cord-015369-72cjogxz 455 6 eine eine NNP cord-015369-72cjogxz 455 7 Herausforderung Herausforderung NNP cord-015369-72cjogxz 456 1 an an DT cord-015369-72cjogxz 456 2 die die NN cord-015369-72cjogxz 457 1 chirurgische chirurgische NNP cord-015369-72cjogxz 457 2 Sanierung Sanierung NNP cord-015369-72cjogxz 457 3 , , , cord-015369-72cjogxz 457 4 anderseits anderseit VBZ cord-015369-72cjogxz 457 5 verlängert verlängert NNP cord-015369-72cjogxz 457 6 sich sich NNP cord-015369-72cjogxz 457 7 bei bei NNP cord-015369-72cjogxz 457 8 zunehmender zunehmender NNP cord-015369-72cjogxz 458 1 Schwere Schwere NNP cord-015369-72cjogxz 458 2 der der NNP cord-015369-72cjogxz 458 3 Infektion Infektion NNP cord-015369-72cjogxz 458 4 die die VB cord-015369-72cjogxz 458 5 Rekonvaleszenzzeit Rekonvaleszenzzeit NNP cord-015369-72cjogxz 458 6 deutlich deutlich NNP cord-015369-72cjogxz 458 7 und und IN cord-015369-72cjogxz 458 8 eine eine NNP cord-015369-72cjogxz 458 9 Restitutio Restitutio NNP cord-015369-72cjogxz 458 10 ad ad NN cord-015369-72cjogxz 458 11 integro integro NNP cord-015369-72cjogxz 458 12 ist ist NNP cord-015369-72cjogxz 458 13 meist meist NNP cord-015369-72cjogxz 458 14 nicht nicht NNP cord-015369-72cjogxz 458 15 mehr mehr NNP cord-015369-72cjogxz 458 16 möglich möglich NNP cord-015369-72cjogxz 458 17 . . . cord-015369-72cjogxz 459 1 Immunhistochemische Immunhistochemische NNP cord-015369-72cjogxz 459 2 Untersuchungen Untersuchungen NNP cord-015369-72cjogxz 459 3 zur zur NNP cord-015369-72cjogxz 459 4 Pathogenese Pathogenese NNP cord-015369-72cjogxz 459 5 posttraumatischer posttraumatischer NN cord-015369-72cjogxz 459 6 und und IN cord-015369-72cjogxz 459 7 postinfektiöser postinfektiöser NNP cord-015369-72cjogxz 460 1 Sehnenadhäsionen Sehnenadhäsionen NNP cord-015369-72cjogxz 460 2 logischer logischer NN cord-015369-72cjogxz 460 3 Narben Narben NNP cord-015369-72cjogxz 460 4 . . . cord-015369-72cjogxz 461 1 Ziel Ziel NNP cord-015369-72cjogxz 461 2 dieser dieser NNP cord-015369-72cjogxz 461 3 Studie Studie NNP cord-015369-72cjogxz 461 4 war war NN cord-015369-72cjogxz 461 5 , , , cord-015369-72cjogxz 461 6 die die VBP cord-015369-72cjogxz 461 7 Rolle Rolle NNP cord-015369-72cjogxz 461 8 des des NNP cord-015369-72cjogxz 461 9 Immunsystems Immunsystems NNP cord-015369-72cjogxz 461 10 bei bei NNP cord-015369-72cjogxz 461 11 der der NNP cord-015369-72cjogxz 461 12 Entstehung Entstehung NNP cord-015369-72cjogxz 461 13 von von NNP cord-015369-72cjogxz 461 14 Sehnenverwachsungen Sehnenverwachsungen NNP cord-015369-72cjogxz 461 15 zu zu NNP cord-015369-72cjogxz 461 16 beleuchten beleuchten NNP cord-015369-72cjogxz 461 17 . . . cord-015369-72cjogxz 462 1 Untersucht Untersucht NNP cord-015369-72cjogxz 462 2 wurde wurde NNP cord-015369-72cjogxz 463 1 Sehnenscheidengewebe Sehnenscheidengewebe NNP cord-015369-72cjogxz 463 2 von von NNP cord-015369-72cjogxz 463 3 10 10 CD cord-015369-72cjogxz 463 4 Patient Patient NNP cord-015369-72cjogxz 463 5 - - HYPH cord-015369-72cjogxz 463 6 Innen Innen NNP cord-015369-72cjogxz 463 7 , , , cord-015369-72cjogxz 463 8 die die VB cord-015369-72cjogxz 463 9 sich sich NNP cord-015369-72cjogxz 463 10 einer einer NNP cord-015369-72cjogxz 463 11 Tenolyse Tenolyse NNP cord-015369-72cjogxz 463 12 unterzogen unterzogen NNP cord-015369-72cjogxz 463 13 . . . cord-015369-72cjogxz 464 1 Sehnenscheidengewebe Sehnenscheidengewebe NNP cord-015369-72cjogxz 464 2 von von NNP cord-015369-72cjogxz 464 3 10 10 CD cord-015369-72cjogxz 465 1 frischen frischen NNP cord-015369-72cjogxz 465 2 Leichen Leichen NNP cord-015369-72cjogxz 465 3 diente diente NNP cord-015369-72cjogxz 465 4 als als NNP cord-015369-72cjogxz 465 5 Kontrolle Kontrolle NNP cord-015369-72cjogxz 465 6 . . . cord-015369-72cjogxz 466 1 Immunsuppressive Immunsuppressive NNP cord-015369-72cjogxz 466 2 Therapie Therapie NNP cord-015369-72cjogxz 466 3 , , , cord-015369-72cjogxz 466 4 neoplastische neoplastische NNP cord-015369-72cjogxz 466 5 oder oder NNP cord-015369-72cjogxz 466 6 infektiöse infektiöse NNP cord-015369-72cjogxz 466 7 Erkrankungen Erkrankungen NNP cord-015369-72cjogxz 466 8 sowie sowie NNP cord-015369-72cjogxz 466 9 chronisch chronisch NNP cord-015369-72cjogxz 466 10 entzündliche entzündliche NNP cord-015369-72cjogxz 466 11 Erkrankungen Erkrankungen NNP cord-015369-72cjogxz 466 12 waren waren VBD cord-015369-72cjogxz 466 13 in in IN cord-015369-72cjogxz 466 14 beiden beiden JJ cord-015369-72cjogxz 466 15 Gruppen Gruppen NNP cord-015369-72cjogxz 466 16 Ausschlusskriterien Ausschlusskriterien NNP cord-015369-72cjogxz 466 17 . . . cord-015369-72cjogxz 467 1 An an DT cord-015369-72cjogxz 467 2 Gefrierschnitten Gefrierschnitten NNP cord-015369-72cjogxz 467 3 wurden wurden VBD cord-015369-72cjogxz 467 4 mit mit NNP cord-015369-72cjogxz 467 5 Hilfe Hilfe NNP cord-015369-72cjogxz 467 6 von von NNP cord-015369-72cjogxz 467 7 monoklonalen monoklonalen NNP cord-015369-72cjogxz 468 1 Antikörpern Antikörpern NNP cord-015369-72cjogxz 468 2 gegen gegen NNP cord-015369-72cjogxz 468 3 T T NNP cord-015369-72cjogxz 468 4 - - HYPH cord-015369-72cjogxz 468 5 Lymphozyten Lymphozyten NNP cord-015369-72cjogxz 468 6 und und VBD cord-015369-72cjogxz 468 7 Makrophagen Makrophagen NNP cord-015369-72cjogxz 468 8 immunhistochemische immunhistochemische NN cord-015369-72cjogxz 468 9 Untersuchungen Untersuchungen NNP cord-015369-72cjogxz 468 10 durchgeführt durchgeführt NN cord-015369-72cjogxz 468 11 . . . cord-015369-72cjogxz 469 1 Dabei Dabei NNP cord-015369-72cjogxz 469 2 wurden wurden NNS cord-015369-72cjogxz 469 3 die die VBP cord-015369-72cjogxz 469 4 T T NNP cord-015369-72cjogxz 469 5 - - HYPH cord-015369-72cjogxz 469 6 Lymphozyten Lymphozyten NNP cord-015369-72cjogxz 469 7 subtypisiert subtypisiert NN cord-015369-72cjogxz 469 8 und und IN cord-015369-72cjogxz 469 9 ihr ihr NNP cord-015369-72cjogxz 469 10 Aktivierungsgrad Aktivierungsgrad NNP cord-015369-72cjogxz 469 11 bestimmt bestimmt NNP cord-015369-72cjogxz 469 12 . . . cord-015369-72cjogxz 470 1 I -PRON- PRP cord-015369-72cjogxz 470 2 m be VBP cord-015369-72cjogxz 471 1 Vergleich Vergleich NNP cord-015369-72cjogxz 471 2 zur zur NNP cord-015369-72cjogxz 471 3 Kontrollgruppe Kontrollgruppe NNP cord-015369-72cjogxz 471 4 zeigte zeigte NNP cord-015369-72cjogxz 471 5 sich sich NNP cord-015369-72cjogxz 472 1 eine eine NNP cord-015369-72cjogxz 472 2 statistisch statistisch NNP cord-015369-72cjogxz 472 3 signifikante signifikante NNP cord-015369-72cjogxz 472 4 Erhöhung Erhöhung NNP cord-015369-72cjogxz 472 5 von von NNP cord-015369-72cjogxz 472 6 T T NNP cord-015369-72cjogxz 472 7 - - HYPH cord-015369-72cjogxz 472 8 Lymphozyten Lymphozyten NNP cord-015369-72cjogxz 472 9 i -PRON- PRP cord-015369-72cjogxz 472 10 m be VBP cord-015369-72cjogxz 472 11 Patientengewebe Patientengewebe NNP cord-015369-72cjogxz 472 12 . . . cord-015369-72cjogxz 473 1 Auch Auch NNP cord-015369-72cjogxz 473 2 die die VBP cord-015369-72cjogxz 473 3 Zahl Zahl NNP cord-015369-72cjogxz 473 4 der der NNP cord-015369-72cjogxz 473 5 zytotoxischen zytotoxischen NNP cord-015369-72cjogxz 473 6 T T NNP cord-015369-72cjogxz 473 7 - - HYPH cord-015369-72cjogxz 473 8 Lymphozyten Lymphozyten NNP cord-015369-72cjogxz 473 9 war war NN cord-015369-72cjogxz 473 10 signifikant signifikant NN cord-015369-72cjogxz 473 11 erhöht erhöht NNP cord-015369-72cjogxz 473 12 , , , cord-015369-72cjogxz 473 13 während während NNP cord-015369-72cjogxz 473 14 die die VBP cord-015369-72cjogxz 473 15 Erhöhung Erhöhung NNP cord-015369-72cjogxz 473 16 der der NNP cord-015369-72cjogxz 473 17 Zahl Zahl NNP cord-015369-72cjogxz 473 18 der der NNP cord-015369-72cjogxz 473 19 Helferzellen Helferzellen NNP cord-015369-72cjogxz 473 20 nicht nicht NNP cord-015369-72cjogxz 473 21 signifikant signifikant NNP cord-015369-72cjogxz 473 22 war war NN cord-015369-72cjogxz 473 23 . . . cord-015369-72cjogxz 474 1 Auch Auch NNP cord-015369-72cjogxz 474 2 die die VBP cord-015369-72cjogxz 474 3 Zahl Zahl NNP cord-015369-72cjogxz 474 4 der der NNP cord-015369-72cjogxz 474 5 aktivierten aktivierten NNP cord-015369-72cjogxz 474 6 T T NNP cord-015369-72cjogxz 474 7 - - HYPH cord-015369-72cjogxz 474 8 Lymphozyten Lymphozyten NNP cord-015369-72cjogxz 474 9 war war NN cord-015369-72cjogxz 474 10 signifikant signifikant NN cord-015369-72cjogxz 474 11 erhöht erhöht NNP cord-015369-72cjogxz 474 12 . . . cord-015369-72cjogxz 475 1 I -PRON- PRP cord-015369-72cjogxz 475 2 m be VBP cord-015369-72cjogxz 475 3 Patientengewebe Patientengewebe NNP cord-015369-72cjogxz 475 4 fanden fanden NNP cord-015369-72cjogxz 475 5 sich sich NNP cord-015369-72cjogxz 476 1 auch auch NNP cord-015369-72cjogxz 476 2 vermehrt vermehrt NNP cord-015369-72cjogxz 476 3 Makrophagen Makrophagen NNP cord-015369-72cjogxz 476 4 , , , cord-015369-72cjogxz 476 5 wobei wobei JJ cord-015369-72cjogxz 476 6 diese diese NNP cord-015369-72cjogxz 476 7 Erhöhung Erhöhung NNP cord-015369-72cjogxz 476 8 nicht nicht NNP cord-015369-72cjogxz 476 9 statistisch statistisch NNP cord-015369-72cjogxz 476 10 signifikant signifikant NNP cord-015369-72cjogxz 476 11 war war NN cord-015369-72cjogxz 476 12 . . . cord-015369-72cjogxz 477 1 Die die VB cord-015369-72cjogxz 477 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 477 3 unserer unserer JJ cord-015369-72cjogxz 477 4 Untersuchungen Untersuchungen NNP cord-015369-72cjogxz 477 5 weisen weisen NNP cord-015369-72cjogxz 477 6 auf auf NNP cord-015369-72cjogxz 477 7 eine eine NNP cord-015369-72cjogxz 477 8 zentrale zentrale NNP cord-015369-72cjogxz 477 9 Rolle Rolle NNP cord-015369-72cjogxz 477 10 der der NNP cord-015369-72cjogxz 477 11 T T NNP cord-015369-72cjogxz 477 12 - - HYPH cord-015369-72cjogxz 477 13 Lymphozyten Lymphozyten NNP cord-015369-72cjogxz 477 14 bei bei NN cord-015369-72cjogxz 477 15 der der NNP cord-015369-72cjogxz 477 16 Entstehung Entstehung NNP cord-015369-72cjogxz 477 17 von von NNP cord-015369-72cjogxz 477 18 Sehnenverwachsungen Sehnenverwachsungen NNP cord-015369-72cjogxz 477 19 hin hin NNP cord-015369-72cjogxz 477 20 . . . cord-015369-72cjogxz 478 1 Weitere Weitere NNP cord-015369-72cjogxz 478 2 Untersuchungen Untersuchungen NNP cord-015369-72cjogxz 478 3 zum zum NNP cord-015369-72cjogxz 478 4 Aktivierungsweg Aktivierungsweg NNP cord-015369-72cjogxz 478 5 , , , cord-015369-72cjogxz 478 6 zur zur NNP cord-015369-72cjogxz 478 7 Interaktion Interaktion NNP cord-015369-72cjogxz 478 8 zwischen zwischen NNP cord-015369-72cjogxz 478 9 Makrophagen Makrophagen NNP cord-015369-72cjogxz 478 10 und und IN cord-015369-72cjogxz 478 11 T T NNP cord-015369-72cjogxz 478 12 - - HYPH cord-015369-72cjogxz 478 13 Lymphozyten Lymphozyten NNP cord-015369-72cjogxz 478 14 sowie sowie XX cord-015369-72cjogxz 478 15 zur zur NNP cord-015369-72cjogxz 478 16 Rolle Rolle NNP cord-015369-72cjogxz 478 17 dendritischer dendritischer NN cord-015369-72cjogxz 478 18 Zellen Zellen NNP cord-015369-72cjogxz 478 19 in in IN cord-015369-72cjogxz 478 20 diesem diesem NNP cord-015369-72cjogxz 478 21 Geschehen Geschehen NNP cord-015369-72cjogxz 478 22 sollen sollen NNP cord-015369-72cjogxz 478 23 zu zu NNP cord-015369-72cjogxz 478 24 einem einem NNP cord-015369-72cjogxz 478 25 weitergehenden weitergehenden NNP cord-015369-72cjogxz 478 26 Verständnis Verständnis NNP cord-015369-72cjogxz 478 27 dieser dieser NNP cord-015369-72cjogxz 478 28 Vorgänge Vorgänge NNP cord-015369-72cjogxz 478 29 führen führen NNP cord-015369-72cjogxz 478 30 . . . cord-015369-72cjogxz 479 1 Der Der NNP cord-015369-72cjogxz 479 2 tiefe tiefe DT cord-015369-72cjogxz 480 1 Infekt infekt NN cord-015369-72cjogxz 480 2 der der NN cord-015369-72cjogxz 480 3 Hand Hand NNP cord-015369-72cjogxz 481 1 -Diagnostik -Diagnostik NNP cord-015369-72cjogxz 481 2 und und IN cord-015369-72cjogxz 481 3 Therapie Therapie NNP cord-015369-72cjogxz 481 4 am be VBP cord-015369-72cjogxz 481 5 Beispiel Beispiel NNP cord-015369-72cjogxz 481 6 zweier zweier NNP cord-015369-72cjogxz 482 1 Fallberichte Fallberichte NNP cord-015369-72cjogxz 482 2 J. J. NNP cord-015369-72cjogxz 482 3 Erhart Erhart NNP cord-015369-72cjogxz 482 4 , , , cord-015369-72cjogxz 482 5 V. V. NNP cord-015369-72cjogxz 482 6 Vécsei Vécsei NNP cord-015369-72cjogxz 482 7 Univ.-Klinik Univ.-Klinik NNP cord-015369-72cjogxz 483 1 für für LS cord-015369-72cjogxz 483 2 Unfallchirurgie Unfallchirurgie NNP cord-015369-72cjogxz 483 3 , , , cord-015369-72cjogxz 483 4 Wien Wien NNP cord-015369-72cjogxz 483 5 , , , cord-015369-72cjogxz 483 6 Austria Austria NNP cord-015369-72cjogxz 483 7 Grundlagen Grundlagen NNP cord-015369-72cjogxz 483 8 . . . cord-015369-72cjogxz 484 1 Der Der NNP cord-015369-72cjogxz 484 2 tiefe tiefe NNP cord-015369-72cjogxz 484 3 Handinfekt Handinfekt NNP cord-015369-72cjogxz 484 4 ist ist NNP cord-015369-72cjogxz 485 1 vital vital NNP cord-015369-72cjogxz 485 2 bedrohlich bedrohlich NNP cord-015369-72cjogxz 485 3 und und IN cord-015369-72cjogxz 485 4 beinträchtigt beinträchtigt NNP cord-015369-72cjogxz 485 5 die die VBP cord-015369-72cjogxz 485 6 Funktion Funktion NNP cord-015369-72cjogxz 485 7 der der NN cord-015369-72cjogxz 485 8 Hand Hand NNP cord-015369-72cjogxz 485 9 . . . cord-015369-72cjogxz 486 1 Diese Diese NNP cord-015369-72cjogxz 486 2 hängt hängt NNP cord-015369-72cjogxz 486 3 von von NNP cord-015369-72cjogxz 486 4 einem einem NNP cord-015369-72cjogxz 486 5 adäquaten adäquaten NNP cord-015369-72cjogxz 486 6 therapeutischen therapeutischen NNP cord-015369-72cjogxz 486 7 Konzept Konzept NNP cord-015369-72cjogxz 486 8 ab ab NNP cord-015369-72cjogxz 486 9 . . . cord-015369-72cjogxz 487 1 Methodik Methodik NNP cord-015369-72cjogxz 487 2 . . . cord-015369-72cjogxz 488 1 Anhand Anhand NNP cord-015369-72cjogxz 488 2 zweier zweier NNP cord-015369-72cjogxz 488 3 Fallberichte Fallberichte NNP cord-015369-72cjogxz 488 4 wird wird NNP cord-015369-72cjogxz 488 5 das das NNP cord-015369-72cjogxz 488 6 Management Management NNP cord-015369-72cjogxz 488 7 der der NNP cord-015369-72cjogxz 488 8 tiefen tiefen NNP cord-015369-72cjogxz 488 9 Handinfektion Handinfektion NNP cord-015369-72cjogxz 488 10 dargestellt dargestellt NNP cord-015369-72cjogxz 488 11 . . . cord-015369-72cjogxz 489 1 Fall fall VB cord-015369-72cjogxz 489 2 1 1 CD cord-015369-72cjogxz 489 3 . . . cord-015369-72cjogxz 490 1 Nach Nach NNP cord-015369-72cjogxz 490 2 einem einem NNP cord-015369-72cjogxz 490 3 Bagatelltrauma Bagatelltrauma NNP cord-015369-72cjogxz 490 4 ohne ohne NNP cord-015369-72cjogxz 490 5 Hautläsion Hautläsion NNP cord-015369-72cjogxz 491 1 kommt kommt NNP cord-015369-72cjogxz 491 2 es es NNP cord-015369-72cjogxz 491 3 zu zu NNP cord-015369-72cjogxz 492 1 einem einem NNP cord-015369-72cjogxz 492 2 tiefen tiefen NNP cord-015369-72cjogxz 492 3 Infekt Infekt NNP cord-015369-72cjogxz 492 4 der der NNP cord-015369-72cjogxz 492 5 Hand Hand NNP cord-015369-72cjogxz 492 6 eines eine NNS cord-015369-72cjogxz 493 1 Mädchens Mädchens NNP cord-015369-72cjogxz 493 2 . . . cord-015369-72cjogxz 494 1 Aufgrund Aufgrund NNP cord-015369-72cjogxz 494 2 der der VBD cord-015369-72cjogxz 494 3 unklaren unklaren NNP cord-015369-72cjogxz 494 4 Ä ä NN cord-015369-72cjogxz 495 1 tiologie tiologie NNP cord-015369-72cjogxz 495 2 wird wird NNP cord-015369-72cjogxz 496 1 ein ein NNP cord-015369-72cjogxz 496 2 MRT MRT NNP cord-015369-72cjogxz 496 3 der der NNP cord-015369-72cjogxz 496 4 Hand Hand NNP cord-015369-72cjogxz 496 5 angefertigt angefertigt NNP cord-015369-72cjogxz 496 6 , , , cord-015369-72cjogxz 496 7 alle alle NNP cord-015369-72cjogxz 496 8 möglichen möglichen NNP cord-015369-72cjogxz 496 9 Ursachen Ursachen NNP cord-015369-72cjogxz 496 10 ausgeschlossen ausgeschlossen NNP cord-015369-72cjogxz 496 11 , , , cord-015369-72cjogxz 496 12 die die VB cord-015369-72cjogxz 497 1 Hand hand NN cord-015369-72cjogxz 497 2 der der NN cord-015369-72cjogxz 497 3 Patientin Patientin NNP cord-015369-72cjogxz 498 1 dorsal dorsal NNP cord-015369-72cjogxz 498 2 und und NNP cord-015369-72cjogxz 498 3 palmar palmar NNP cord-015369-72cjogxz 498 4 debridiert debridiert NNP cord-015369-72cjogxz 498 5 und und IN cord-015369-72cjogxz 498 6 mit mit NNP cord-015369-72cjogxz 498 7 einem einem NNP cord-015369-72cjogxz 498 8 Vacuumverband Vacuumverband NNP cord-015369-72cjogxz 498 9 behandelt behandelt NNP cord-015369-72cjogxz 498 10 . . . cord-015369-72cjogxz 499 1 I -PRON- PRP cord-015369-72cjogxz 499 2 m be VBP cord-015369-72cjogxz 499 3 Abstrich Abstrich NNP cord-015369-72cjogxz 499 4 finden finden NNP cord-015369-72cjogxz 499 5 sich sich NNP cord-015369-72cjogxz 499 6 dorsal dorsal NNP cord-015369-72cjogxz 499 7 und und NNP cord-015369-72cjogxz 499 8 palmar palmar NNP cord-015369-72cjogxz 499 9 ß ß NN cord-015369-72cjogxz 499 10 - - HYPH cord-015369-72cjogxz 499 11 hämolisierende hämolisierende NNP cord-015369-72cjogxz 499 12 Strektokokken Strektokokken NNP cord-015369-72cjogxz 499 13 . . . cord-015369-72cjogxz 500 1 Es Es NNP cord-015369-72cjogxz 500 2 wird wird NNP cord-015369-72cjogxz 500 3 lediglich lediglich NNP cord-015369-72cjogxz 501 1 ein ein NNP cord-015369-72cjogxz 501 2 Revisionseingriff Revisionseingriff NNP cord-015369-72cjogxz 501 3 zum zum NN cord-015369-72cjogxz 501 4 sekundären sekundären NN cord-015369-72cjogxz 501 5 Weichteilverschluss Weichteilverschluss NNP cord-015369-72cjogxz 501 6 benötigt benötigt NNP cord-015369-72cjogxz 501 7 . . . cord-015369-72cjogxz 502 1 Zur Zur NNP cord-015369-72cjogxz 502 2 Durchführung Durchführung NNP cord-015369-72cjogxz 502 3 der der NNP cord-015369-72cjogxz 502 4 Ergotherapie Ergotherapie NNP cord-015369-72cjogxz 502 5 bedarf bedarf NN cord-015369-72cjogxz 503 1 es es XX cord-015369-72cjogxz 504 1 eine eine NNP cord-015369-72cjogxz 504 2 maximale maximale NNP cord-015369-72cjogxz 504 3 Schmerzausschaltung Schmerzausschaltung NNP cord-015369-72cjogxz 504 4 unter unter JJ cord-015369-72cjogxz 504 5 psychotherapeutischer psychotherapeutischer NNP cord-015369-72cjogxz 504 6 Betreuung Betreuung NNP cord-015369-72cjogxz 504 7 . . . cord-015369-72cjogxz 505 1 Sie Sie NNP cord-015369-72cjogxz 505 2 erlangt erlangt NNP cord-015369-72cjogxz 505 3 eine eine FW cord-015369-72cjogxz 505 4 sehr sehr NNP cord-015369-72cjogxz 505 5 gute gute NNP cord-015369-72cjogxz 505 6 Funktion Funktion NNP cord-015369-72cjogxz 505 7 der der NNP cord-015369-72cjogxz 505 8 Hand Hand NNP cord-015369-72cjogxz 505 9 . . . cord-015369-72cjogxz 506 1 Fall fall NN cord-015369-72cjogxz 506 2 2 2 CD cord-015369-72cjogxz 506 3 . . . cord-015369-72cjogxz 507 1 Ein Ein NNP cord-015369-72cjogxz 507 2 ausgedehnter ausgedehnter NN cord-015369-72cjogxz 507 3 Defekt Defekt NNP cord-015369-72cjogxz 507 4 der der NN cord-015369-72cjogxz 507 5 Weichteile Weichteile NNP cord-015369-72cjogxz 508 1 und und NNP cord-015369-72cjogxz 509 1 Knochen Knochen NNP cord-015369-72cjogxz 509 2 der der NNP cord-015369-72cjogxz 509 3 Handwurzel Handwurzel NNP cord-015369-72cjogxz 510 1 und und NNP cord-015369-72cjogxz 510 2 des des NNP cord-015369-72cjogxz 510 3 Handrü Handrü NNP cord-015369-72cjogxz 510 4 ckens ckens NNP cord-015369-72cjogxz 511 1 ist ist NNP cord-015369-72cjogxz 511 2 nach nach NNP cord-015369-72cjogxz 511 3 3 3 CD cord-015369-72cjogxz 511 4 Tagen Tagen NNP cord-015369-72cjogxz 511 5 septisch septisch NN cord-015369-72cjogxz 511 6 . . . cord-015369-72cjogxz 512 1 Die die VB cord-015369-72cjogxz 512 2 Wunde Wunde NNP cord-015369-72cjogxz 512 3 wird wird NNP cord-015369-72cjogxz 512 4 debridiert debridiert NN cord-015369-72cjogxz 512 5 , , , cord-015369-72cjogxz 512 6 die die VB cord-015369-72cjogxz 512 7 Defekthöhlen Defekthöhlen NNP cord-015369-72cjogxz 512 8 mit mit NNP cord-015369-72cjogxz 512 9 Septopalketten Septopalketten NNP cord-015369-72cjogxz 512 10 gefü gefü NNPS cord-015369-72cjogxz 512 11 llt llt NNP cord-015369-72cjogxz 512 12 , , , cord-015369-72cjogxz 512 13 mit mit NNP cord-015369-72cjogxz 512 14 einem einem NNP cord-015369-72cjogxz 512 15 Radialislappen Radialislappen NNP cord-015369-72cjogxz 512 16 gedeckt gedeckt NNS cord-015369-72cjogxz 512 17 und und IN cord-015369-72cjogxz 512 18 zur zur NNP cord-015369-72cjogxz 512 19 Ausheilung Ausheilung NNP cord-015369-72cjogxz 512 20 gebracht gebracht NNP cord-015369-72cjogxz 512 21 . . . cord-015369-72cjogxz 513 1 Nach Nach NNP cord-015369-72cjogxz 513 2 Infektsanierung Infektsanierung NNP cord-015369-72cjogxz 513 3 wird wird NNP cord-015369-72cjogxz 513 4 das das NNP cord-015369-72cjogxz 513 5 Handgelenk Handgelenk NNP cord-015369-72cjogxz 513 6 arthrodetisiert arthrodetisiert NN cord-015369-72cjogxz 513 7 , , , cord-015369-72cjogxz 513 8 die die VB cord-015369-72cjogxz 513 9 Streckfunktion Streckfunktion NNP cord-015369-72cjogxz 513 10 aller aller FW cord-015369-72cjogxz 513 11 Langfinger Langfinger NNP cord-015369-72cjogxz 513 12 durch durch NNP cord-015369-72cjogxz 513 13 Interposition Interposition NNP cord-015369-72cjogxz 513 14 von von NNP cord-015369-72cjogxz 513 15 Adduktorensehnen Adduktorensehnen NNP cord-015369-72cjogxz 513 16 wiederhergestellt wiederhergestellt JJS cord-015369-72cjogxz 513 17 . . . cord-015369-72cjogxz 514 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 514 2 . . . cord-015369-72cjogxz 515 1 Durch Durch NNP cord-015369-72cjogxz 515 2 die die VBP cord-015369-72cjogxz 516 1 Präsentation präsentation NN cord-015369-72cjogxz 516 2 des des NN cord-015369-72cjogxz 517 1 ersten ersten NNP cord-015369-72cjogxz 518 1 Falles Falles NNP cord-015369-72cjogxz 518 2 weisen weisen NNP cord-015369-72cjogxz 519 1 wir wir NNP cord-015369-72cjogxz 519 2 auf auf NNP cord-015369-72cjogxz 519 3 das das NNP cord-015369-72cjogxz 519 4 seltene seltene NNP cord-015369-72cjogxz 519 5 Auftreten Auftreten NNP cord-015369-72cjogxz 519 6 eines eines NNP cord-015369-72cjogxz 519 7 Spontanab Spontanab NNP cord-015369-72cjogxz 519 8 - - HYPH cord-015369-72cjogxz 519 9 szesses szesses NNP cord-015369-72cjogxz 519 10 der der NNP cord-015369-72cjogxz 519 11 kindlichen kindlichen NNP cord-015369-72cjogxz 519 12 Hand Hand NNP cord-015369-72cjogxz 519 13 hin hin NNP cord-015369-72cjogxz 519 14 . . . cord-015369-72cjogxz 520 1 Trotz Trotz NNP cord-015369-72cjogxz 520 2 der der NNP cord-015369-72cjogxz 520 3 Dringlichkeit Dringlichkeit NNP cord-015369-72cjogxz 520 4 der der NNP cord-015369-72cjogxz 520 5 Operation Operation NNP cord-015369-72cjogxz 520 6 sollte sollte NNP cord-015369-72cjogxz 520 7 eine eine NNP cord-015369-72cjogxz 520 8 sorgfältige sorgfältige NNP cord-015369-72cjogxz 521 1 Abwägung Abwägung NNP cord-015369-72cjogxz 521 2 der der NNP cord-015369-72cjogxz 521 3 Lokalisation Lokalisation NNP cord-015369-72cjogxz 521 4 der der NN cord-015369-72cjogxz 521 5 Inzisionen Inzisionen NNP cord-015369-72cjogxz 521 6 erfolgen erfolgen NNP cord-015369-72cjogxz 521 7 , , , cord-015369-72cjogxz 521 8 um um UH cord-015369-72cjogxz 521 9 eine eine NNP cord-015369-72cjogxz 521 10 rasche rasche NN cord-015369-72cjogxz 521 11 Infektbeherrschung Infektbeherrschung NNP cord-015369-72cjogxz 521 12 durch durch NNP cord-015369-72cjogxz 521 13 radikales radikale NNS cord-015369-72cjogxz 521 14 , , , cord-015369-72cjogxz 521 15 in in IN cord-015369-72cjogxz 521 16 diesem diesem NNP cord-015369-72cjogxz 521 17 Fall Fall NNP cord-015369-72cjogxz 521 18 beidseitiges beidseitige VBZ cord-015369-72cjogxz 521 19 Debridement Debridement NNP cord-015369-72cjogxz 521 20 zu zu IN cord-015369-72cjogxz 521 21 erzielen erzielen NN cord-015369-72cjogxz 521 22 . . . cord-015369-72cjogxz 522 1 Wir Wir NNP cord-015369-72cjogxz 522 2 weisen weisen NNP cord-015369-72cjogxz 522 3 auf auf NNP cord-015369-72cjogxz 522 4 die die VBP cord-015369-72cjogxz 522 5 extrem extrem NNP cord-015369-72cjogxz 522 6 aufwändige aufwändige NNP cord-015369-72cjogxz 522 7 Nachbehandlung Nachbehandlung NNP cord-015369-72cjogxz 522 8 hin hin NNP cord-015369-72cjogxz 522 9 . . . cord-015369-72cjogxz 523 1 Der Der NNP cord-015369-72cjogxz 523 2 zweite zweite NNP cord-015369-72cjogxz 524 1 Fall fall VB cord-015369-72cjogxz 524 2 ist ist FW cord-015369-72cjogxz 524 3 wegen wegen NNP cord-015369-72cjogxz 524 4 der der NNP cord-015369-72cjogxz 524 5 Doppelfunktion Doppelfunktion NNP cord-015369-72cjogxz 524 6 der der NNP cord-015369-72cjogxz 524 7 regionalen regionalen NNP cord-015369-72cjogxz 525 1 Lappenplastik Lappenplastik NNP cord-015369-72cjogxz 525 2 zur zur NNP cord-015369-72cjogxz 525 3 gleichzeitigen gleichzeitigen NNP cord-015369-72cjogxz 525 4 Weichteildeckung Weichteildeckung NNP cord-015369-72cjogxz 525 5 und und IN cord-015369-72cjogxz 525 6 Infektbeherrschung Infektbeherrschung NNP cord-015369-72cjogxz 525 7 erwähnenswert erwähnenswert NNP cord-015369-72cjogxz 525 8 . . . cord-015369-72cjogxz 526 1 Er er UH cord-015369-72cjogxz 526 2 zeichnet zeichnet NNP cord-015369-72cjogxz 526 3 sich sich NNP cord-015369-72cjogxz 526 4 durch durch NNP cord-015369-72cjogxz 526 5 einen einen NNP cord-015369-72cjogxz 526 6 sicheren sicheren NN cord-015369-72cjogxz 526 7 Erhalt Erhalt NNP cord-015369-72cjogxz 526 8 der der NNP cord-015369-72cjogxz 526 9 Hand Hand NNP cord-015369-72cjogxz 526 10 und und WDT cord-015369-72cjogxz 526 11 die die VBP cord-015369-72cjogxz 526 12 vollständige vollständige NNP cord-015369-72cjogxz 526 13 Wiederherstellung Wiederherstellung NNP cord-015369-72cjogxz 526 14 der der NNP cord-015369-72cjogxz 526 15 Fingerfunktion Fingerfunktion NNP cord-015369-72cjogxz 526 16 aus aus NNP cord-015369-72cjogxz 526 17 . . . cord-015369-72cjogxz 527 1 Free free JJ cord-015369-72cjogxz 527 2 tissue tissue NN cord-015369-72cjogxz 527 3 transfer transfer NN cord-015369-72cjogxz 527 4 for for IN cord-015369-72cjogxz 527 5 complex complex JJ cord-015369-72cjogxz 527 6 infections infection NNS cord-015369-72cjogxz 527 7 of of IN cord-015369-72cjogxz 527 8 the the DT cord-015369-72cjogxz 527 9 handa handa NNP cord-015369-72cjogxz 527 10 retrospective retrospective JJ cord-015369-72cjogxz 527 11 analysis analysis NN cord-015369-72cjogxz 527 12 Grundlagen Grundlagen NNP cord-015369-72cjogxz 527 13 . . . cord-015369-72cjogxz 528 1 Schwere Schwere NNP cord-015369-72cjogxz 529 1 Infektionen Infektionen NNP cord-015369-72cjogxz 530 1 i -PRON- PRP cord-015369-72cjogxz 530 2 m be VBP cord-015369-72cjogxz 531 1 Handbereich Handbereich NNP cord-015369-72cjogxz 531 2 bedürfen bedürfen NNP cord-015369-72cjogxz 531 3 nach nach NNP cord-015369-72cjogxz 531 4 ausgedehntem ausgedehntem NNP cord-015369-72cjogxz 532 1 radikalen radikalen NNP cord-015369-72cjogxz 532 2 Débridement Débridement NNP cord-015369-72cjogxz 532 3 und und XX cord-015369-72cjogxz 533 1 Bannung Bannung NNP cord-015369-72cjogxz 533 2 der der NNP cord-015369-72cjogxz 534 1 Infektion Infektion NNP cord-015369-72cjogxz 534 2 häufig häufig NNP cord-015369-72cjogxz 534 3 einer einer NNP cord-015369-72cjogxz 534 4 komplexen komplexen VBD cord-015369-72cjogxz 534 5 Defektdeckung Defektdeckung NNP cord-015369-72cjogxz 534 6 . . . cord-015369-72cjogxz 535 1 Diese Diese NNP cord-015369-72cjogxz 535 2 retrospektive retrospektive NN cord-015369-72cjogxz 535 3 Analyse Analyse NNP cord-015369-72cjogxz 535 4 umfasst umfasst NNP cord-015369-72cjogxz 536 1 5 5 LS cord-015369-72cjogxz 536 2 Patienten Patienten NNP cord-015369-72cjogxz 536 3 ( ( -LRB- cord-015369-72cjogxz 536 4 4 4 CD cord-015369-72cjogxz 536 5 männlich männlich NNP cord-015369-72cjogxz 536 6 , , , cord-015369-72cjogxz 536 7 1 1 CD cord-015369-72cjogxz 536 8 weiblich weiblich NNP cord-015369-72cjogxz 536 9 ) ) -RRB- cord-015369-72cjogxz 536 10 , , , cord-015369-72cjogxz 536 11 welche welche NNP cord-015369-72cjogxz 536 12 zwischen zwischen NNP cord-015369-72cjogxz 536 13 Juni Juni NNP cord-015369-72cjogxz 536 14 2006 2006 CD cord-015369-72cjogxz 537 1 und und NNP cord-015369-72cjogxz 538 1 März März NNP cord-015369-72cjogxz 538 2 2008 2008 CD cord-015369-72cjogxz 538 3 mit mit NNP cord-015369-72cjogxz 538 4 ausgedehnten ausgedehnten NNP cord-015369-72cjogxz 539 1 Infektionen Infektionen NNP cord-015369-72cjogxz 539 2 an an DT cord-015369-72cjogxz 539 3 der der NNP cord-015369-72cjogxz 539 4 Hand Hand NNP cord-015369-72cjogxz 539 5 operiert operiert NN cord-015369-72cjogxz 539 6 worden worden NNP cord-015369-72cjogxz 539 7 sind sind NNP cord-015369-72cjogxz 539 8 . . . cord-015369-72cjogxz 540 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 540 2 . . . cord-015369-72cjogxz 541 1 Infektursache Infektursache NNP cord-015369-72cjogxz 541 2 war war NN cord-015369-72cjogxz 541 3 in in IN cord-015369-72cjogxz 541 4 drei drei NNP cord-015369-72cjogxz 541 5 Fällen Fällen NNP cord-015369-72cjogxz 541 6 ein ein NNP cord-015369-72cjogxz 541 7 Hundebiss Hundebiss NNP cord-015369-72cjogxz 541 8 und und IN cord-015369-72cjogxz 541 9 in in IN cord-015369-72cjogxz 541 10 zweien zweien NNP cord-015369-72cjogxz 541 11 ein ein NNP cord-015369-72cjogxz 541 12 Bagatelltrauma Bagatelltrauma NNP cord-015369-72cjogxz 541 13 . . . cord-015369-72cjogxz 542 1 In in IN cord-015369-72cjogxz 542 2 zwei zwei NNP cord-015369-72cjogxz 542 3 Fällen Fällen NNP cord-015369-72cjogxz 542 4 war war NN cord-015369-72cjogxz 542 5 der der NN cord-015369-72cjogxz 542 6 Hautweichteilinfekt Hautweichteilinfekt NNP cord-015369-72cjogxz 542 7 auf auf NNS cord-015369-72cjogxz 542 8 den den NN cord-015369-72cjogxz 542 9 Handrü Handrü NNP cord-015369-72cjogxz 542 10 cken cken NNP cord-015369-72cjogxz 542 11 , , , cord-015369-72cjogxz 542 12 in in IN cord-015369-72cjogxz 542 13 einem einem NNP cord-015369-72cjogxz 542 14 auf auf NNP cord-015369-72cjogxz 542 15 die die VBP cord-015369-72cjogxz 542 16 Hohlhand Hohlhand NNP cord-015369-72cjogxz 542 17 beschränkt beschränkt NNP cord-015369-72cjogxz 542 18 . . . cord-015369-72cjogxz 543 1 Zwei Zwei NNP cord-015369-72cjogxz 543 2 Patienten Patienten NNP cord-015369-72cjogxz 543 3 zeigten zeigten XX cord-015369-72cjogxz 544 1 einen einen NNP cord-015369-72cjogxz 544 2 kombinierten kombinierten NNP cord-015369-72cjogxz 544 3 dorsalen dorsalen NNP cord-015369-72cjogxz 545 1 und und NNP cord-015369-72cjogxz 545 2 palmaren palmaren NNP cord-015369-72cjogxz 545 3 Infekt Infekt NNP cord-015369-72cjogxz 545 4 . . . cord-015369-72cjogxz 546 1 Bei Bei NNP cord-015369-72cjogxz 546 2 einem einem NNP cord-015369-72cjogxz 547 1 Patienten Patienten NNP cord-015369-72cjogxz 547 2 fand fand VBP cord-015369-72cjogxz 547 3 sich sich NNP cord-015369-72cjogxz 547 4 neben neben NNP cord-015369-72cjogxz 547 5 einer einer NNP cord-015369-72cjogxz 547 6 ausgeprägten ausgeprägten NNP cord-015369-72cjogxz 547 7 streck streck NNP cord-015369-72cjogxz 547 8 - - HYPH cord-015369-72cjogxz 547 9 und und NNP cord-015369-72cjogxz 548 1 beugeseitigen beugeseitigen NNP cord-015369-72cjogxz 548 2 Infektlokalisation Infektlokalisation NNP cord-015369-72cjogxz 549 1 auch auch NNP cord-015369-72cjogxz 549 2 ein ein NNP cord-015369-72cjogxz 549 3 Handgelenksempyem Handgelenksempyem NNP cord-015369-72cjogxz 549 4 mit mit NNP cord-015369-72cjogxz 549 5 bereits bereits NNP cord-015369-72cjogxz 549 6 stattgefundener stattgefundener NNP cord-015369-72cjogxz 549 7 Knochenzerstörung Knochenzerstörung NNP cord-015369-72cjogxz 549 8 . . . cord-015369-72cjogxz 550 1 4 4 CD cord-015369-72cjogxz 550 2 der der NN cord-015369-72cjogxz 550 3 5 5 CD cord-015369-72cjogxz 550 4 Patienten Patienten NNP cord-015369-72cjogxz 550 5 wurden wurden VBN cord-015369-72cjogxz 550 6 vor vor NNP cord-015369-72cjogxz 550 7 der der NNP cord-015369-72cjogxz 550 8 Einweisung Einweisung NNP cord-015369-72cjogxz 550 9 in in IN cord-015369-72cjogxz 550 10 die die NN cord-015369-72cjogxz 551 1 Spezialklinik spezialklinik JJ cord-015369-72cjogxz 551 2 auswärtig auswärtig NN cord-015369-72cjogxz 551 3 durch durch NNP cord-015369-72cjogxz 551 4 Stichinzisionen Stichinzisionen NNP cord-015369-72cjogxz 551 5 mit mit NNP cord-015369-72cjogxz 551 6 Drainagen Drainagen NNP cord-015369-72cjogxz 551 7 und/ und/ CD cord-015369-72cjogxz 552 1 oder oder NNP cord-015369-72cjogxz 552 2 begrenzte begrenzte NNP cord-015369-72cjogxz 552 3 Nekrosektomien Nekrosektomien NNP cord-015369-72cjogxz 552 4 chirurgisch chirurgisch JJ cord-015369-72cjogxz 552 5 vorbehandelt vorbehandelt NNS cord-015369-72cjogxz 552 6 . . . cord-015369-72cjogxz 553 1 Bei Bei NNP cord-015369-72cjogxz 553 2 drei drei NNP cord-015369-72cjogxz 554 1 Patienten Patienten NNP cord-015369-72cjogxz 554 2 wurde wurde NN cord-015369-72cjogxz 554 3 nach nach NNP cord-015369-72cjogxz 554 4 einmaligem einmaligem NNP cord-015369-72cjogxz 554 5 Débridement Débridement NNP cord-015369-72cjogxz 554 6 , , , cord-015369-72cjogxz 554 7 bei bei NNP cord-015369-72cjogxz 554 8 zweien zweien NNP cord-015369-72cjogxz 554 9 nach nach NNP cord-015369-72cjogxz 554 10 Mehrfachdébridements Mehrfachdébridements NNP cord-015369-72cjogxz 554 11 die die VBP cord-015369-72cjogxz 554 12 Indikation Indikation NNP cord-015369-72cjogxz 554 13 zur zur NNP cord-015369-72cjogxz 554 14 mikrochirurgischen mikrochirurgischen NN cord-015369-72cjogxz 554 15 Defektdeckung Defektdeckung NNP cord-015369-72cjogxz 554 16 gestellt gestellt NNP cord-015369-72cjogxz 554 17 . . . cord-015369-72cjogxz 555 1 Diese Diese NNP cord-015369-72cjogxz 555 2 wurde wurde NN cord-015369-72cjogxz 555 3 mit mit NNP cord-015369-72cjogxz 556 1 2 2 LS cord-015369-72cjogxz 556 2 Splited Splited NNP cord-015369-72cjogxz 556 3 - - HYPH cord-015369-72cjogxz 556 4 Lat.-dorsi Lat.-dorsi NNP cord-015369-72cjogxz 556 5 - - HYPH cord-015369-72cjogxz 556 6 Lappen Lappen NNP cord-015369-72cjogxz 556 7 , , , cord-015369-72cjogxz 556 8 2 2 CD cord-015369-72cjogxz 556 9 Serratus Serratus NNP cord-015369-72cjogxz 556 10 - - HYPH cord-015369-72cjogxz 556 11 ant.-Lappen ant.-Lappen NNP cord-015369-72cjogxz 556 12 und und IN cord-015369-72cjogxz 556 13 1 1 CD cord-015369-72cjogxz 556 14 Lat.-Oberarm Lat.-Oberarm NNP cord-015369-72cjogxz 556 15 - - HYPH cord-015369-72cjogxz 556 16 Lappen Lappen NNP cord-015369-72cjogxz 556 17 durchgefü durchgefü NN cord-015369-72cjogxz 556 18 hrt hrt NNP cord-015369-72cjogxz 556 19 . . . cord-015369-72cjogxz 557 1 Alle Alle NNP cord-015369-72cjogxz 557 2 Lappenplastiken Lappenplastiken NNP cord-015369-72cjogxz 557 3 zeigten zeigten XX cord-015369-72cjogxz 557 4 einen einen NNP cord-015369-72cjogxz 557 5 unkomplizierten unkomplizierten NNP cord-015369-72cjogxz 557 6 primären primären NNP cord-015369-72cjogxz 557 7 Heilungsverlauf Heilungsverlauf NNP cord-015369-72cjogxz 557 8 ; ; : cord-015369-72cjogxz 557 9 in in IN cord-015369-72cjogxz 557 10 zwei zwei NNP cord-015369-72cjogxz 557 11 Fällen Fällen NNP cord-015369-72cjogxz 557 12 erfolgte erfolgte NN cord-015369-72cjogxz 557 13 eine eine NN cord-015369-72cjogxz 557 14 operative operative NN cord-015369-72cjogxz 558 1 Nachkorrektur Nachkorrektur NNP cord-015369-72cjogxz 558 2 i -PRON- PRP cord-015369-72cjogxz 558 3 m be VBP cord-015369-72cjogxz 558 4 Sinne Sinne NNP cord-015369-72cjogxz 558 5 von von NNP cord-015369-72cjogxz 558 6 Kontrakturauflösung Kontrakturauflösung NNP cord-015369-72cjogxz 558 7 , , , cord-015369-72cjogxz 558 8 Lappenausdü Lappenausdü NNP cord-015369-72cjogxz 558 9 nnung nnung NNP cord-015369-72cjogxz 558 10 und und IN cord-015369-72cjogxz 558 11 Liposuktion Liposuktion NNP cord-015369-72cjogxz 558 12 . . . cord-015369-72cjogxz 559 1 4 4 CD cord-015369-72cjogxz 559 2 der der NN cord-015369-72cjogxz 559 3 5 5 CD cord-015369-72cjogxz 560 1 Patienten Patienten NNP cord-015369-72cjogxz 560 2 verzeichneten verzeichneten NNP cord-015369-72cjogxz 560 3 nach nach NNP cord-015369-72cjogxz 560 4 intensiver intensiver NNP cord-015369-72cjogxz 561 1 postoperativer postoperativer NNP cord-015369-72cjogxz 561 2 Ergo Ergo NNP cord-015369-72cjogxz 561 3 - - HYPH cord-015369-72cjogxz 561 4 und und NNP cord-015369-72cjogxz 561 5 Physiotherapie Physiotherapie NNP cord-015369-72cjogxz 561 6 bereits bereits NNP cord-015369-72cjogxz 561 7 ab ab NNP cord-015369-72cjogxz 561 8 der der NNP cord-015369-72cjogxz 561 9 12 12 CD cord-015369-72cjogxz 561 10 . . . cord-015369-72cjogxz 562 1 postoperativen postoperativen NNP cord-015369-72cjogxz 562 2 Woche Woche NNP cord-015369-72cjogxz 562 3 einen einen NNP cord-015369-72cjogxz 562 4 vollständigen vollständigen NNP cord-015369-72cjogxz 562 5 aktiven aktiven NNP cord-015369-72cjogxz 562 6 Faustschluss Faustschluss NNP cord-015369-72cjogxz 562 7 , , , cord-015369-72cjogxz 562 8 sowie sowie NNP cord-015369-72cjogxz 562 9 Spitz Spitz NNP cord-015369-72cjogxz 562 10 - - HYPH cord-015369-72cjogxz 562 11 und und NNP cord-015369-72cjogxz 562 12 Schlü Schlü NNP cord-015369-72cjogxz 562 13 sselgriff sselgriff NNP cord-015369-72cjogxz 562 14 . . . cord-015369-72cjogxz 563 1 Die die VB cord-015369-72cjogxz 563 2 ROM ROM NNP cord-015369-72cjogxz 563 3 an an DT cord-015369-72cjogxz 563 4 Hand hand NN cord-015369-72cjogxz 563 5 - - HYPH cord-015369-72cjogxz 563 6 und und NNP cord-015369-72cjogxz 563 7 sämtlichen sämtlichen NNP cord-015369-72cjogxz 563 8 Fingergelenken Fingergelenken NNP cord-015369-72cjogxz 563 9 betrug betrug NNP cord-015369-72cjogxz 563 10 zu zu NNP cord-015369-72cjogxz 563 11 diesem diesem NNP cord-015369-72cjogxz 563 12 Zeitpunkt Zeitpunkt NNP cord-015369-72cjogxz 563 13 80 80 CD cord-015369-72cjogxz 563 14 % % NN cord-015369-72cjogxz 563 15 der der NN cord-015369-72cjogxz 563 16 nicht nicht NNP cord-015369-72cjogxz 563 17 betroffenen betroffenen NNP cord-015369-72cjogxz 563 18 Hand Hand NNP cord-015369-72cjogxz 563 19 . . . cord-015369-72cjogxz 564 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 564 2 . . . cord-015369-72cjogxz 565 1 Der Der NNP cord-015369-72cjogxz 565 2 mikrochirurgische mikrochirurgische NNP cord-015369-72cjogxz 565 3 Transfer Transfer NNP cord-015369-72cjogxz 565 4 von von NNP cord-015369-72cjogxz 565 5 fasziokutanen fasziokutanen NNP cord-015369-72cjogxz 565 6 - - HYPH cord-015369-72cjogxz 565 7 oder oder NNP cord-015369-72cjogxz 566 1 Muskel Muskel NNP cord-015369-72cjogxz 566 2 - - HYPH cord-015369-72cjogxz 566 3 Lappenplastiken Lappenplastiken NNP cord-015369-72cjogxz 566 4 stellt stellt NNP cord-015369-72cjogxz 567 1 eine eine NNP cord-015369-72cjogxz 567 2 zuverlässige zuverlässige NNP cord-015369-72cjogxz 567 3 Methode Methode NNP cord-015369-72cjogxz 567 4 der der NNP cord-015369-72cjogxz 567 5 Defektdeckung Defektdeckung NNP cord-015369-72cjogxz 567 6 bei bei NNP cord-015369-72cjogxz 567 7 ausgedehnten ausgedehnten NNP cord-015369-72cjogxz 568 1 Handinfekten Handinfekten NNP cord-015369-72cjogxz 568 2 dar dar NNP cord-015369-72cjogxz 568 3 . . . cord-015369-72cjogxz 569 1 Abhängig Abhängig NNP cord-015369-72cjogxz 569 2 von von NNP cord-015369-72cjogxz 569 3 Ausdehnung Ausdehnung NNP cord-015369-72cjogxz 569 4 und und IN cord-015369-72cjogxz 569 5 Lokalisation Lokalisation NNP cord-015369-72cjogxz 569 6 des des FW cord-015369-72cjogxz 569 7 Defektes Defektes NNP cord-015369-72cjogxz 569 8 steht steht NNP cord-015369-72cjogxz 569 9 die die VBP cord-015369-72cjogxz 569 10 Lappenauswahl Lappenauswahl NNP cord-015369-72cjogxz 569 11 zum zum NNP cord-015369-72cjogxz 570 1 Erreichen Erreichen NNP cord-015369-72cjogxz 570 2 eines eines NNP cord-015369-72cjogxz 570 3 zufriedenstellenden zufriedenstellenden NNP cord-015369-72cjogxz 570 4 funktionellen funktionellen NNP cord-015369-72cjogxz 570 5 und und NNP cord-015369-72cjogxz 571 1 ästhetischen ästhetischen NNP cord-015369-72cjogxz 571 2 Ergebnisses Ergebnisses NNP cord-015369-72cjogxz 572 1 i -PRON- PRP cord-015369-72cjogxz 572 2 m be VBP cord-015369-72cjogxz 572 3 Vordergrund Vordergrund NNP cord-015369-72cjogxz 572 4 . . . cord-015369-72cjogxz 573 1 Background background NN cord-015369-72cjogxz 573 2 . . . cord-015369-72cjogxz 574 1 Oncolytic oncolytic JJ cord-015369-72cjogxz 574 2 viral viral JJ cord-015369-72cjogxz 574 3 therapy therapy NN cord-015369-72cjogxz 574 4 may may MD cord-015369-72cjogxz 574 5 offer offer VB cord-015369-72cjogxz 574 6 a a DT cord-015369-72cjogxz 574 7 promising promising JJ cord-015369-72cjogxz 574 8 alternative alternative NN cord-015369-72cjogxz 574 9 in in IN cord-015369-72cjogxz 574 10 highly highly RB cord-015369-72cjogxz 574 11 aggressive aggressive JJ cord-015369-72cjogxz 574 12 tumors tumor NNS cord-015369-72cjogxz 574 13 such such JJ cord-015369-72cjogxz 574 14 as as IN cord-015369-72cjogxz 574 15 malignant malignant JJ cord-015369-72cjogxz 574 16 pleural pleural JJ cord-015369-72cjogxz 574 17 mesothelioma mesothelioma NN cord-015369-72cjogxz 574 18 ( ( -LRB- cord-015369-72cjogxz 574 19 MPM MPM NNP cord-015369-72cjogxz 574 20 ) ) -RRB- cord-015369-72cjogxz 574 21 , , , cord-015369-72cjogxz 574 22 that that WDT cord-015369-72cjogxz 574 23 are be VBP cord-015369-72cjogxz 574 24 insensitive insensitive JJ cord-015369-72cjogxz 574 25 to to IN cord-015369-72cjogxz 574 26 established establish VBN cord-015369-72cjogxz 574 27 chemotherapy chemotherapy NN cord-015369-72cjogxz 574 28 and and CC cord-015369-72cjogxz 574 29 radiation radiation NN cord-015369-72cjogxz 574 30 regimes regime NNS cord-015369-72cjogxz 574 31 . . . cord-015369-72cjogxz 575 1 In in IN cord-015369-72cjogxz 575 2 the the DT cord-015369-72cjogxz 575 3 following following JJ cord-015369-72cjogxz 575 4 study study NN cord-015369-72cjogxz 575 5 , , , cord-015369-72cjogxz 575 6 the the DT cord-015369-72cjogxz 575 7 oncolytic oncolytic JJ cord-015369-72cjogxz 575 8 efficacy efficacy NN cord-015369-72cjogxz 575 9 of of IN cord-015369-72cjogxz 575 10 Newcastle Newcastle NNP cord-015369-72cjogxz 575 11 disease disease NN cord-015369-72cjogxz 575 12 virus virus NN cord-015369-72cjogxz 575 13 ( ( -LRB- cord-015369-72cjogxz 575 14 NDV NDV NNP cord-015369-72cjogxz 575 15 ( ( -LRB- cord-015369-72cjogxz 575 16 F3aa)-GFP f3aa)-gfp CD cord-015369-72cjogxz 575 17 ) ) -RRB- cord-015369-72cjogxz 575 18 on on IN cord-015369-72cjogxz 575 19 MPM MPM NNP cord-015369-72cjogxz 575 20 is be VBZ cord-015369-72cjogxz 575 21 tested test VBN cord-015369-72cjogxz 575 22 and and CC cord-015369-72cjogxz 575 23 investigated investigate VBN cord-015369-72cjogxz 575 24 by by IN cord-015369-72cjogxz 575 25 bioluminescence bioluminescence NN cord-015369-72cjogxz 575 26 imaging imaging NN cord-015369-72cjogxz 575 27 . . . cord-015369-72cjogxz 576 1 Methods method NNS cord-015369-72cjogxz 576 2 . . . cord-015369-72cjogxz 577 1 NDV(F3aa)-GFP NDV(F3aa)-GFP NNP cord-015369-72cjogxz 577 2 was be VBD cord-015369-72cjogxz 577 3 tested test VBN cord-015369-72cjogxz 577 4 for for IN cord-015369-72cjogxz 577 5 viral viral JJ cord-015369-72cjogxz 577 6 cytotoxicity cytotoxicity NN cord-015369-72cjogxz 577 7 at at IN cord-015369-72cjogxz 577 8 different different JJ cord-015369-72cjogxz 577 9 multiplicities multiplicity NNS cord-015369-72cjogxz 577 10 of of IN cord-015369-72cjogxz 577 11 infection infection NN cord-015369-72cjogxz 577 12 ( ( -LRB- cord-015369-72cjogxz 577 13 MOI MOI NNP cord-015369-72cjogxz 577 14 ) ) -RRB- cord-015369-72cjogxz 577 15 against against IN cord-015369-72cjogxz 577 16 several several JJ cord-015369-72cjogxz 577 17 mesothelioma mesothelioma NN cord-015369-72cjogxz 577 18 cell cell NN cord-015369-72cjogxz 577 19 lines line NNS cord-015369-72cjogxz 577 20 in in IN cord-015369-72cjogxz 577 21 vitro vitro FW cord-015369-72cjogxz 577 22 . . . cord-015369-72cjogxz 578 1 For for IN cord-015369-72cjogxz 578 2 in in IN cord-015369-72cjogxz 578 3 vivo vivo NN cord-015369-72cjogxz 578 4 studies study NNS cord-015369-72cjogxz 578 5 , , , cord-015369-72cjogxz 578 6 MSTO MSTO NNP cord-015369-72cjogxz 578 7 211H 211h CD cord-015369-72cjogxz 578 8 cells cell NNS cord-015369-72cjogxz 578 9 were be VBD cord-015369-72cjogxz 578 10 transduced transduce VBN cord-015369-72cjogxz 578 11 with with IN cord-015369-72cjogxz 578 12 firefly firefly NN cord-015369-72cjogxz 578 13 ( ( -LRB- cord-015369-72cjogxz 578 14 Photinus Photinus NNP cord-015369-72cjogxz 578 15 pyralis pyralis NNP cord-015369-72cjogxz 578 16 ) ) -RRB- cord-015369-72cjogxz 579 1 luciferase luciferase NNP cord-015369-72cjogxz 579 2 ( ( -LRB- cord-015369-72cjogxz 579 3 FLuc)encoding fluc)encode VBG cord-015369-72cjogxz 579 4 cDNAs cDNAs -RRB- cord-015369-72cjogxz 579 5 ( ( -LRB- cord-015369-72cjogxz 579 6 MSTO MSTO NNP cord-015369-72cjogxz 579 7 td td NNP cord-015369-72cjogxz 579 8 211H 211h CD cord-015369-72cjogxz 579 9 ) ) -RRB- cord-015369-72cjogxz 579 10 . . . cord-015369-72cjogxz 580 1 Tumor tumor NN cord-015369-72cjogxz 580 2 - - HYPH cord-015369-72cjogxz 580 3 bearing bear VBG cord-015369-72cjogxz 580 4 animals animal NNS cord-015369-72cjogxz 581 1 ( ( -LRB- cord-015369-72cjogxz 581 2 1e 1e NNP cord-015369-72cjogxz 581 3 7 7 CD cord-015369-72cjogxz 581 4 cells cell NNS cord-015369-72cjogxz 581 5 injected inject VBN cord-015369-72cjogxz 581 6 intrapleurally intrapleurally RB cord-015369-72cjogxz 581 7 ) ) -RRB- cord-015369-72cjogxz 581 8 were be VBD cord-015369-72cjogxz 581 9 treated treat VBN cord-015369-72cjogxz 581 10 with with IN cord-015369-72cjogxz 581 11 either either CC cord-015369-72cjogxz 581 12 single single JJ cord-015369-72cjogxz 581 13 or or CC cord-015369-72cjogxz 581 14 multiple multiple JJ cord-015369-72cjogxz 581 15 doses dose NNS cord-015369-72cjogxz 581 16 of of IN cord-015369-72cjogxz 581 17 NDV(F3aa)-GFP NDV(F3aa)-GFP NNP cord-015369-72cjogxz 582 1 ( ( -LRB- cord-015369-72cjogxz 582 2 1e 1e NNP cord-015369-72cjogxz 582 3 7 7 CD cord-015369-72cjogxz 582 4 plaque plaque NN cord-015369-72cjogxz 582 5 - - HYPH cord-015369-72cjogxz 582 6 forming form VBG cord-015369-72cjogxz 582 7 units unit NNS cord-015369-72cjogxz 582 8 pfu pfu NN cord-015369-72cjogxz 582 9 should should MD cord-015369-72cjogxz 582 10 be be VB cord-015369-72cjogxz 582 11 given give VBN cord-015369-72cjogxz 582 12 as as IN cord-015369-72cjogxz 582 13 log log NN cord-015369-72cjogxz 582 14 10 10 CD cord-015369-72cjogxz 582 15 ) ) -RRB- cord-015369-72cjogxz 582 16 at at IN cord-015369-72cjogxz 582 17 different different JJ cord-015369-72cjogxz 582 18 time time NN cord-015369-72cjogxz 582 19 points point NNS cord-015369-72cjogxz 582 20 ( ( -LRB- cord-015369-72cjogxz 582 21 days day NNS cord-015369-72cjogxz 582 22 1 1 CD cord-015369-72cjogxz 582 23 , , , cord-015369-72cjogxz 582 24 3 3 CD cord-015369-72cjogxz 582 25 , , , cord-015369-72cjogxz 582 26 and and CC cord-015369-72cjogxz 582 27 10 10 CD cord-015369-72cjogxz 582 28 ) ) -RRB- cord-015369-72cjogxz 582 29 and and CC cord-015369-72cjogxz 582 30 followed follow VBN cord-015369-72cjogxz 582 31 by by IN cord-015369-72cjogxz 582 32 bioluminescence bioluminescence NN cord-015369-72cjogxz 582 33 imaging imaging NN cord-015369-72cjogxz 582 34 . . . cord-015369-72cjogxz 583 1 Results result NNS cord-015369-72cjogxz 583 2 . . . cord-015369-72cjogxz 584 1 Mesothelioma mesothelioma NN cord-015369-72cjogxz 584 2 cell cell NN cord-015369-72cjogxz 584 3 lines line NNS cord-015369-72cjogxz 584 4 exhibited exhibit VBD cord-015369-72cjogxz 584 5 susceptibility susceptibility NN cord-015369-72cjogxz 584 6 to to IN cord-015369-72cjogxz 584 7 NDV ndv JJ cord-015369-72cjogxz 584 8 lysis lysis NN cord-015369-72cjogxz 584 9 in in IN cord-015369-72cjogxz 584 10 the the DT cord-015369-72cjogxz 584 11 following following JJ cord-015369-72cjogxz 584 12 order order NN cord-015369-72cjogxz 584 13 of of IN cord-015369-72cjogxz 584 14 sensitivity sensitivity NN cord-015369-72cjogxz 584 15 : : : cord-015369-72cjogxz 584 16 MSTO MSTO NNP cord-015369-72cjogxz 584 17 211H 211h CD cord-015369-72cjogxz 585 1 > > XX cord-015369-72cjogxz 586 1 MSTO MSTO NNP cord-015369-72cjogxz 586 2 td td NNP cord-015369-72cjogxz 586 3 211H 211h CD cord-015369-72cjogxz 587 1 > > XX cord-015369-72cjogxz 588 1 H-2452 h-2452 CD cord-015369-72cjogxz 589 1 > > XX cord-015369-72cjogxz 590 1 VAMT VAMT NNP cord-015369-72cjogxz 590 2 > > XX cord-015369-72cjogxz 591 1 JMN JMN NNP cord-015369-72cjogxz 592 1 ( ( -LRB- cord-015369-72cjogxz 592 2 No no DT cord-015369-72cjogxz 592 3 effect effect NN cord-015369-72cjogxz 592 4 in in IN cord-015369-72cjogxz 592 5 the the DT cord-015369-72cjogxz 592 6 cell cell NN cord-015369-72cjogxz 592 7 lines line NNS cord-015369-72cjogxz 593 1 H-2052 h-2052 JJ cord-015369-72cjogxz 593 2 , , , cord-015369-72cjogxz 593 3 H-2373 h-2373 CD cord-015369-72cjogxz 593 4 , , , cord-015369-72cjogxz 593 5 and and CC cord-015369-72cjogxz 593 6 HMESO HMESO NNP cord-015369-72cjogxz 593 7 ) ) -RRB- cord-015369-72cjogxz 593 8 . . . cord-015369-72cjogxz 594 1 In in IN cord-015369-72cjogxz 594 2 vivo vivo NN cord-015369-72cjogxz 594 3 studies study NNS cord-015369-72cjogxz 594 4 with with IN cord-015369-72cjogxz 594 5 MSTO MSTO NNP cord-015369-72cjogxz 594 6 td td NNP cord-015369-72cjogxz 594 7 211H 211h CD cord-015369-72cjogxz 594 8 cells cell NNS cord-015369-72cjogxz 594 9 showed show VBD cord-015369-72cjogxz 594 10 complete complete JJ cord-015369-72cjogxz 594 11 response response NN cord-015369-72cjogxz 594 12 to to IN cord-015369-72cjogxz 594 13 viral viral JJ cord-015369-72cjogxz 594 14 therapy therapy NN cord-015369-72cjogxz 594 15 in in IN cord-015369-72cjogxz 594 16 > > $ cord-015369-72cjogxz 594 17 75 75 CD cord-015369-72cjogxz 594 18 % % NN cord-015369-72cjogxz 594 19 of of IN cord-015369-72cjogxz 594 20 the the DT cord-015369-72cjogxz 594 21 animals animal NNS cord-015369-72cjogxz 594 22 , , , cord-015369-72cjogxz 594 23 resulting result VBG cord-015369-72cjogxz 594 24 in in IN cord-015369-72cjogxz 594 25 eradication eradication NN cord-015369-72cjogxz 594 26 of of IN cord-015369-72cjogxz 594 27 tumor tumor NN cord-015369-72cjogxz 594 28 detected detect VBN cord-015369-72cjogxz 594 29 by by IN cord-015369-72cjogxz 594 30 bioluminescence bioluminescence NN cord-015369-72cjogxz 594 31 . . . cord-015369-72cjogxz 595 1 72 72 CD cord-015369-72cjogxz 595 2 % % NN cord-015369-72cjogxz 595 3 of of IN cord-015369-72cjogxz 595 4 the the DT cord-015369-72cjogxz 595 5 virally virally RB cord-015369-72cjogxz 595 6 treated treat VBN cord-015369-72cjogxz 595 7 animals animal NNS cord-015369-72cjogxz 595 8 survived survive VBD cord-015369-72cjogxz 595 9 > > XX cord-015369-72cjogxz 595 10 50 50 CD cord-015369-72cjogxz 595 11 days day NNS cord-015369-72cjogxz 595 12 after after IN cord-015369-72cjogxz 595 13 tumor tumor NN cord-015369-72cjogxz 595 14 injection injection NN cord-015369-72cjogxz 595 15 . . . cord-015369-72cjogxz 596 1 No no DT cord-015369-72cjogxz 596 2 signs sign NNS cord-015369-72cjogxz 596 3 of of IN cord-015369-72cjogxz 596 4 toxicity toxicity NN cord-015369-72cjogxz 596 5 were be VBD cord-015369-72cjogxz 596 6 observed observe VBN cord-015369-72cjogxz 596 7 in in IN cord-015369-72cjogxz 596 8 the the DT cord-015369-72cjogxz 596 9 treatment treatment NN cord-015369-72cjogxz 596 10 group group NN cord-015369-72cjogxz 596 11 . . . cord-015369-72cjogxz 597 1 In in IN cord-015369-72cjogxz 597 2 addition addition NN cord-015369-72cjogxz 597 3 , , , cord-015369-72cjogxz 597 4 multiple multiple JJ cord-015369-72cjogxz 597 5 treatments treatment NNS cord-015369-72cjogxz 597 6 showed show VBD cord-015369-72cjogxz 597 7 a a DT cord-015369-72cjogxz 597 8 significantly significantly RB cord-015369-72cjogxz 597 9 better well JJR cord-015369-72cjogxz 597 10 response response NN cord-015369-72cjogxz 597 11 compared compare VBN cord-015369-72cjogxz 597 12 with with IN cord-015369-72cjogxz 597 13 single single JJ cord-015369-72cjogxz 597 14 treatment treatment NN cord-015369-72cjogxz 597 15 ( ( -LRB- cord-015369-72cjogxz 597 16 p p NN cord-015369-72cjogxz 597 17 ¼ ¼ CD cord-015369-72cjogxz 597 18 0.005 0.005 CD cord-015369-72cjogxz 597 19 ) ) -RRB- cord-015369-72cjogxz 597 20 . . . cord-015369-72cjogxz 598 1 Conclusions conclusion NNS cord-015369-72cjogxz 598 2 . . . cord-015369-72cjogxz 599 1 NDV NDV NNP cord-015369-72cjogxz 599 2 appears appear VBZ cord-015369-72cjogxz 599 3 to to TO cord-015369-72cjogxz 599 4 be be VB cord-015369-72cjogxz 599 5 an an DT cord-015369-72cjogxz 599 6 efficient efficient JJ cord-015369-72cjogxz 599 7 viral viral JJ cord-015369-72cjogxz 599 8 oncolytic oncolytic JJ cord-015369-72cjogxz 599 9 agent agent NN cord-015369-72cjogxz 599 10 in in IN cord-015369-72cjogxz 599 11 therapy therapy NN cord-015369-72cjogxz 599 12 of of IN cord-015369-72cjogxz 599 13 malignant malignant JJ cord-015369-72cjogxz 599 14 pleural pleural JJ cord-015369-72cjogxz 599 15 mesothelioma mesothelioma NN cord-015369-72cjogxz 599 16 in in IN cord-015369-72cjogxz 599 17 a a DT cord-015369-72cjogxz 599 18 murine murine JJ cord-015369-72cjogxz 599 19 model model NN cord-015369-72cjogxz 599 20 , , , cord-015369-72cjogxz 599 21 and and CC cord-015369-72cjogxz 599 22 warrants warrant NNS cord-015369-72cjogxz 599 23 further further JJ cord-015369-72cjogxz 599 24 investigation investigation NN cord-015369-72cjogxz 599 25 as as IN cord-015369-72cjogxz 599 26 a a DT cord-015369-72cjogxz 599 27 potential potential JJ cord-015369-72cjogxz 599 28 therapeutic therapeutic JJ cord-015369-72cjogxz 599 29 agent agent NN cord-015369-72cjogxz 599 30 . . . cord-015369-72cjogxz 600 1 University University NNP cord-015369-72cjogxz 600 2 Clinic Clinic NNP cord-015369-72cjogxz 600 3 for for IN cord-015369-72cjogxz 600 4 Surgery surgery NN cord-015369-72cjogxz 600 5 , , , cord-015369-72cjogxz 600 6 Graz Graz NNP cord-015369-72cjogxz 600 7 , , , cord-015369-72cjogxz 600 8 Austria Austria NNP cord-015369-72cjogxz 600 9 ; ; : cord-015369-72cjogxz 600 10 2 2 CD cord-015369-72cjogxz 600 11 Institute Institute NNP cord-015369-72cjogxz 600 12 for for IN cord-015369-72cjogxz 600 13 Pathology Pathology NNP cord-015369-72cjogxz 600 14 , , , cord-015369-72cjogxz 600 15 Graz Graz NNP cord-015369-72cjogxz 600 16 , , , cord-015369-72cjogxz 600 17 Austria Austria NNP cord-015369-72cjogxz 600 18 Background Background NNP cord-015369-72cjogxz 600 19 . . . cord-015369-72cjogxz 601 1 Isolation isolation NN cord-015369-72cjogxz 601 2 by by IN cord-015369-72cjogxz 601 3 size size NN cord-015369-72cjogxz 601 4 of of IN cord-015369-72cjogxz 601 5 epithelial epithelial JJ cord-015369-72cjogxz 601 6 tumour tumour NN cord-015369-72cjogxz 601 7 cells cell NNS cord-015369-72cjogxz 601 8 ( ( -LRB- cord-015369-72cjogxz 601 9 ISET ISET NNP cord-015369-72cjogxz 601 10 ) ) -RRB- cord-015369-72cjogxz 601 11 is be VBZ cord-015369-72cjogxz 601 12 an an DT cord-015369-72cjogxz 601 13 innovative innovative JJ cord-015369-72cjogxz 601 14 method method NN cord-015369-72cjogxz 601 15 for for IN cord-015369-72cjogxz 601 16 the the DT cord-015369-72cjogxz 601 17 detection detection NN cord-015369-72cjogxz 601 18 of of IN cord-015369-72cjogxz 601 19 circulating circulate VBG cord-015369-72cjogxz 601 20 tumour tumour NN cord-015369-72cjogxz 601 21 cells cell NNS cord-015369-72cjogxz 601 22 in in IN cord-015369-72cjogxz 601 23 blood blood NN cord-015369-72cjogxz 601 24 . . . cord-015369-72cjogxz 602 1 We -PRON- PRP cord-015369-72cjogxz 602 2 want want VBP cord-015369-72cjogxz 602 3 to to TO cord-015369-72cjogxz 602 4 report report VB cord-015369-72cjogxz 602 5 our -PRON- PRP$ cord-015369-72cjogxz 602 6 preliminary preliminary JJ cord-015369-72cjogxz 602 7 experiences experience NNS cord-015369-72cjogxz 602 8 with with IN cord-015369-72cjogxz 602 9 this this DT cord-015369-72cjogxz 602 10 method method NN cord-015369-72cjogxz 602 11 . . . cord-015369-72cjogxz 603 1 Methods method NNS cord-015369-72cjogxz 603 2 . . . cord-015369-72cjogxz 604 1 Blood blood NN cord-015369-72cjogxz 604 2 of of IN cord-015369-72cjogxz 604 3 20 20 CD cord-015369-72cjogxz 604 4 patients patient NNS cord-015369-72cjogxz 604 5 with with IN cord-015369-72cjogxz 604 6 liver liver NN cord-015369-72cjogxz 604 7 metastases metastasis NNS cord-015369-72cjogxz 604 8 from from IN cord-015369-72cjogxz 604 9 colorectal colorectal JJ cord-015369-72cjogxz 604 10 cancer cancer NN cord-015369-72cjogxz 604 11 and and CC cord-015369-72cjogxz 604 12 of of IN cord-015369-72cjogxz 604 13 five five CD cord-015369-72cjogxz 604 14 patients patient NNS cord-015369-72cjogxz 604 15 with with IN cord-015369-72cjogxz 604 16 benign benign JJ cord-015369-72cjogxz 604 17 liver liver NN cord-015369-72cjogxz 604 18 lesions lesion NNS cord-015369-72cjogxz 604 19 was be VBD cord-015369-72cjogxz 604 20 analyzed analyze VBN cord-015369-72cjogxz 604 21 for for IN cord-015369-72cjogxz 604 22 the the DT cord-015369-72cjogxz 604 23 presence presence NN cord-015369-72cjogxz 604 24 of of IN cord-015369-72cjogxz 604 25 circulating circulate VBG cord-015369-72cjogxz 604 26 tumour tumour NN cord-015369-72cjogxz 604 27 cells cell NNS cord-015369-72cjogxz 604 28 . . . cord-015369-72cjogxz 605 1 Therefore therefore RB cord-015369-72cjogxz 605 2 blood blood NN cord-015369-72cjogxz 605 3 samples sample NNS cord-015369-72cjogxz 605 4 were be VBD cord-015369-72cjogxz 605 5 filtrated filtrate VBN cord-015369-72cjogxz 605 6 through through IN cord-015369-72cjogxz 605 7 a a DT cord-015369-72cjogxz 605 8 translucent translucent JJ cord-015369-72cjogxz 605 9 polycarbonate polycarbonate NN cord-015369-72cjogxz 605 10 filter filter NN cord-015369-72cjogxz 605 11 . . . cord-015369-72cjogxz 606 1 Epithelial epithelial JJ cord-015369-72cjogxz 606 2 cells cell NNS cord-015369-72cjogxz 606 3 were be VBD cord-015369-72cjogxz 606 4 retained retain VBN cord-015369-72cjogxz 606 5 on on IN cord-015369-72cjogxz 606 6 the the DT cord-015369-72cjogxz 606 7 filter filter NN cord-015369-72cjogxz 606 8 due due IN cord-015369-72cjogxz 606 9 to to IN cord-015369-72cjogxz 606 10 their -PRON- PRP$ cord-015369-72cjogxz 606 11 large large JJ cord-015369-72cjogxz 606 12 size size NN cord-015369-72cjogxz 606 13 and and CC cord-015369-72cjogxz 606 14 thus thus RB cord-015369-72cjogxz 606 15 separated separate VBN cord-015369-72cjogxz 606 16 from from IN cord-015369-72cjogxz 606 17 smaller small JJR cord-015369-72cjogxz 606 18 blood blood NN cord-015369-72cjogxz 606 19 particles particle NNS cord-015369-72cjogxz 606 20 . . . cord-015369-72cjogxz 607 1 Afterwards afterwards RB cord-015369-72cjogxz 607 2 the the DT cord-015369-72cjogxz 607 3 filter filter NN cord-015369-72cjogxz 607 4 was be VBD cord-015369-72cjogxz 607 5 stained stain VBN cord-015369-72cjogxz 607 6 and and CC cord-015369-72cjogxz 607 7 evaluated evaluate VBN cord-015369-72cjogxz 607 8 by by IN cord-015369-72cjogxz 607 9 light light JJ cord-015369-72cjogxz 607 10 microscopy microscopy NNS cord-015369-72cjogxz 607 11 . . . cord-015369-72cjogxz 608 1 Tumour tumour NN cord-015369-72cjogxz 608 2 cells cell NNS cord-015369-72cjogxz 608 3 were be VBD cord-015369-72cjogxz 608 4 identified identify VBN cord-015369-72cjogxz 608 5 by by IN cord-015369-72cjogxz 608 6 cytomorphological cytomorphological JJ cord-015369-72cjogxz 608 7 criteria criterion NNS cord-015369-72cjogxz 608 8 's 's POS cord-015369-72cjogxz 608 9 . . . cord-015369-72cjogxz 609 1 Results result NNS cord-015369-72cjogxz 609 2 . . . cord-015369-72cjogxz 610 1 No no DT cord-015369-72cjogxz 610 2 patient patient JJ cord-015369-72cjogxz 610 3 with with IN cord-015369-72cjogxz 610 4 a a DT cord-015369-72cjogxz 610 5 benign benign JJ cord-015369-72cjogxz 610 6 liver liver NN cord-015369-72cjogxz 610 7 lesion lesion NN cord-015369-72cjogxz 610 8 had have VBD cord-015369-72cjogxz 610 9 detectable detectable JJ cord-015369-72cjogxz 610 10 tumour tumour NN cord-015369-72cjogxz 610 11 cells cell NNS cord-015369-72cjogxz 610 12 in in IN cord-015369-72cjogxz 610 13 blood blood NN cord-015369-72cjogxz 610 14 , , , cord-015369-72cjogxz 610 15 but but CC cord-015369-72cjogxz 610 16 eight eight CD cord-015369-72cjogxz 610 17 of of IN cord-015369-72cjogxz 610 18 the the DT cord-015369-72cjogxz 610 19 twenty twenty CD cord-015369-72cjogxz 610 20 patients patient NNS cord-015369-72cjogxz 610 21 with with IN cord-015369-72cjogxz 610 22 liver liver NN cord-015369-72cjogxz 610 23 metastases metastasis NNS cord-015369-72cjogxz 610 24 . . . cord-015369-72cjogxz 611 1 See see VB cord-015369-72cjogxz 611 2 the the DT cord-015369-72cjogxz 611 3 following follow VBG cord-015369-72cjogxz 611 4 table table NN cord-015369-72cjogxz 611 5 . . . cord-015369-72cjogxz 612 1 The the DT cord-015369-72cjogxz 612 2 difference difference NN cord-015369-72cjogxz 612 3 concerning concern VBG cord-015369-72cjogxz 612 4 the the DT cord-015369-72cjogxz 612 5 recurrence recurrence NN cord-015369-72cjogxz 612 6 rate rate NN cord-015369-72cjogxz 612 7 between between IN cord-015369-72cjogxz 612 8 the the DT cord-015369-72cjogxz 612 9 two two CD cord-015369-72cjogxz 612 10 groups group NNS cord-015369-72cjogxz 612 11 was be VBD cord-015369-72cjogxz 612 12 statistically statistically RB cord-015369-72cjogxz 612 13 significant significant JJ cord-015369-72cjogxz 612 14 ( ( -LRB- cord-015369-72cjogxz 612 15 p p NN cord-015369-72cjogxz 612 16 < < XX cord-015369-72cjogxz 612 17 0.05 0.05 CD cord-015369-72cjogxz 612 18 ) ) -RRB- cord-015369-72cjogxz 612 19 . . . cord-015369-72cjogxz 613 1 Conclusions conclusion NNS cord-015369-72cjogxz 613 2 . . . cord-015369-72cjogxz 614 1 It -PRON- PRP cord-015369-72cjogxz 614 2 is be VBZ cord-015369-72cjogxz 614 3 possible possible JJ cord-015369-72cjogxz 614 4 to to TO cord-015369-72cjogxz 614 5 detect detect VB cord-015369-72cjogxz 614 6 circulating circulate VBG cord-015369-72cjogxz 614 7 tumour tumour NN cord-015369-72cjogxz 614 8 cells cell NNS cord-015369-72cjogxz 614 9 in in IN cord-015369-72cjogxz 614 10 blood blood NN cord-015369-72cjogxz 614 11 on on IN cord-015369-72cjogxz 614 12 basis basis NN cord-015369-72cjogxz 614 13 of of IN cord-015369-72cjogxz 614 14 their -PRON- PRP$ cord-015369-72cjogxz 614 15 size size NN cord-015369-72cjogxz 614 16 . . . cord-015369-72cjogxz 615 1 The the DT cord-015369-72cjogxz 615 2 most most RBS cord-015369-72cjogxz 615 3 important important JJ cord-015369-72cjogxz 615 4 advantage advantage NN cord-015369-72cjogxz 615 5 of of IN cord-015369-72cjogxz 615 6 this this DT cord-015369-72cjogxz 615 7 method method NN cord-015369-72cjogxz 615 8 is be VBZ cord-015369-72cjogxz 615 9 the the DT cord-015369-72cjogxz 615 10 ability ability NN cord-015369-72cjogxz 615 11 to to TO cord-015369-72cjogxz 615 12 isolate isolate VB cord-015369-72cjogxz 615 13 the the DT cord-015369-72cjogxz 615 14 tumour tumour NN cord-015369-72cjogxz 615 15 cells cell NNS cord-015369-72cjogxz 615 16 without without IN cord-015369-72cjogxz 615 17 damaging damage VBG cord-015369-72cjogxz 615 18 their -PRON- PRP$ cord-015369-72cjogxz 615 19 morphology morphology NN cord-015369-72cjogxz 615 20 . . . cord-015369-72cjogxz 616 1 So so RB cord-015369-72cjogxz 616 2 the the DT cord-015369-72cjogxz 616 3 isolated isolated JJ cord-015369-72cjogxz 616 4 cells cell NNS cord-015369-72cjogxz 616 5 can can MD cord-015369-72cjogxz 616 6 be be VB cord-015369-72cjogxz 616 7 used use VBN cord-015369-72cjogxz 616 8 for for IN cord-015369-72cjogxz 616 9 further further JJ cord-015369-72cjogxz 616 10 analysis analysis NN cord-015369-72cjogxz 616 11 . . . cord-015369-72cjogxz 617 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 617 2 . . . cord-015369-72cjogxz 618 1 Höhere Höhere NNP cord-015369-72cjogxz 618 2 Konzentrationen Konzentrationen NNP cord-015369-72cjogxz 618 3 i -PRON- PRP cord-015369-72cjogxz 618 4 m be VBP cord-015369-72cjogxz 618 5 Tumorgewebe Tumorgewebe NNP cord-015369-72cjogxz 618 6 durch durch NNP cord-015369-72cjogxz 618 7 drug drug NN cord-015369-72cjogxz 618 8 targeting targeting NN cord-015369-72cjogxz 618 9 erhöhen erhöhen NNP cord-015369-72cjogxz 618 10 die die VB cord-015369-72cjogxz 618 11 Responserate Responserate NNP cord-015369-72cjogxz 618 12 sowie sowie NNP cord-015369-72cjogxz 618 13 das das NNP cord-015369-72cjogxz 618 14 Gesamtüberleben Gesamtüberleben NNP cord-015369-72cjogxz 618 15 . . . cord-015369-72cjogxz 619 1 Einen Einen NNP cord-015369-72cjogxz 619 2 neuartigen neuartigen NNP cord-015369-72cjogxz 619 3 experimentellen experimentellen NNP cord-015369-72cjogxz 619 4 Ansatz Ansatz NNP cord-015369-72cjogxz 619 5 stellt stellt NNP cord-015369-72cjogxz 619 6 die die VBP cord-015369-72cjogxz 619 7 Applikation Applikation NNP cord-015369-72cjogxz 619 8 von von NNP cord-015369-72cjogxz 619 9 in in IN cord-015369-72cjogxz 619 10 Erythrozyten Erythrozyten NNP cord-015369-72cjogxz 619 11 verkapselten verkapselten NN cord-015369-72cjogxz 619 12 Chemotherapeutika Chemotherapeutika NNP cord-015369-72cjogxz 619 13 ( ( -LRB- cord-015369-72cjogxz 619 14 5-FU 5-fu CD cord-015369-72cjogxz 619 15 ) ) -RRB- cord-015369-72cjogxz 619 16 dar dar NNP cord-015369-72cjogxz 619 17 . . . cord-015369-72cjogxz 620 1 I -PRON- PRP cord-015369-72cjogxz 621 1 m m NNP cord-015369-72cjogxz 621 2 lebertumortragenden lebertumortragenden NNP cord-015369-72cjogxz 621 3 Modell Modell NNP cord-015369-72cjogxz 621 4 sollten sollten NNP cord-015369-72cjogxz 621 5 in in IN cord-015369-72cjogxz 621 6 Erythrozyten Erythrozyten NNP cord-015369-72cjogxz 621 7 verkapseltes verkapseltes NNP cord-015369-72cjogxz 622 1 5-FU 5-fu CD cord-015369-72cjogxz 622 2 erstmals erstmals NNP cord-015369-72cjogxz 622 3 appliziert appliziert NNP cord-015369-72cjogxz 622 4 werden werden NNP cord-015369-72cjogxz 622 5 . . . cord-015369-72cjogxz 623 1 Zielsetzung Zielsetzung NNP cord-015369-72cjogxz 623 2 war war NN cord-015369-72cjogxz 623 3 die die VBP cord-015369-72cjogxz 623 4 technische technische NNP cord-015369-72cjogxz 623 5 Machbarkeit Machbarkeit NNP cord-015369-72cjogxz 623 6 einer einer NNP cord-015369-72cjogxz 623 7 Verkapselung Verkapselung NNP cord-015369-72cjogxz 623 8 von von NNP cord-015369-72cjogxz 623 9 5-FU 5-fu CD cord-015369-72cjogxz 623 10 , , , cord-015369-72cjogxz 623 11 die die VB cord-015369-72cjogxz 623 12 Bestimmung Bestimmung NNP cord-015369-72cjogxz 623 13 der der NNP cord-015369-72cjogxz 623 14 Biokompatibilität Biokompatibilität NNP cord-015369-72cjogxz 623 15 der der NNP cord-015369-72cjogxz 623 16 5-FU 5-fu CD cord-015369-72cjogxz 623 17 - - HYPH cord-015369-72cjogxz 623 18 Erythrozyten erythrozyten NN cord-015369-72cjogxz 624 1 sowie sowie UH cord-015369-72cjogxz 624 2 die die VBP cord-015369-72cjogxz 624 3 Messung Messung NNP cord-015369-72cjogxz 624 4 der der NNP cord-015369-72cjogxz 625 1 5-FU 5-fu LS cord-015369-72cjogxz 625 2 - - : cord-015369-72cjogxz 625 3 Konzentration konzentration NN cord-015369-72cjogxz 625 4 i -PRON- PRP cord-015369-72cjogxz 625 5 m be VBP cord-015369-72cjogxz 625 6 Tumorgewebe Tumorgewebe NNP cord-015369-72cjogxz 625 7 . . . cord-015369-72cjogxz 626 1 Methodik Methodik NNP cord-015369-72cjogxz 626 2 . . . cord-015369-72cjogxz 627 1 Als Als NNP cord-015369-72cjogxz 627 2 Tiermodell Tiermodell NNP cord-015369-72cjogxz 627 3 dienten dienten VBD cord-015369-72cjogxz 627 4 60 60 CD cord-015369-72cjogxz 627 5 WAG WAG NNP cord-015369-72cjogxz 627 6 - - HYPH cord-015369-72cjogxz 627 7 Ratten Ratten NNP cord-015369-72cjogxz 627 8 , , , cord-015369-72cjogxz 628 1 denen denen NNP cord-015369-72cjogxz 628 2 CC531-Tumorzellen CC531-Tumorzellen NNP cord-015369-72cjogxz 628 3 der der NNP cord-015369-72cjogxz 628 4 Leber Leber NNP cord-015369-72cjogxz 628 5 subkapsulär subkapsulär NN cord-015369-72cjogxz 628 6 appliziert appliziert NNP cord-015369-72cjogxz 628 7 wurden wurden NNP cord-015369-72cjogxz 628 8 . . . cord-015369-72cjogxz 629 1 Nach Nach NNP cord-015369-72cjogxz 629 2 Ausbildung Ausbildung NNP cord-015369-72cjogxz 629 3 makroskopisch makroskopisch NN cord-015369-72cjogxz 629 4 fassbarer fassbarer NN cord-015369-72cjogxz 629 5 Solitärtumoren Solitärtumoren NNP cord-015369-72cjogxz 629 6 folgte folgte NN cord-015369-72cjogxz 629 7 die die VBP cord-015369-72cjogxz 629 8 Applikation Applikation NNP cord-015369-72cjogxz 629 9 von von NNP cord-015369-72cjogxz 629 10 verkapselten verkapselten NNP cord-015369-72cjogxz 629 11 Erythrozyten Erythrozyten NNP cord-015369-72cjogxz 629 12 der der NNP cord-015369-72cjogxz 629 13 Ratte Ratte NNP cord-015369-72cjogxz 629 14 , , , cord-015369-72cjogxz 629 15 die die VBP cord-015369-72cjogxz 629 16 nach nach NNP cord-015369-72cjogxz 629 17 einem einem NNP cord-015369-72cjogxz 629 18 hypoosmotischen hypoosmotischen NNP cord-015369-72cjogxz 629 19 Dilutionsprozeß Dilutionsprozeß NNP cord-015369-72cjogxz 629 20 mit mit NNP cord-015369-72cjogxz 629 21 5-FU 5-fu CD cord-015369-72cjogxz 629 22 beladen beladen NNP cord-015369-72cjogxz 629 23 worden worden NNP cord-015369-72cjogxz 629 24 waren waren NNP cord-015369-72cjogxz 629 25 . . . cord-015369-72cjogxz 630 1 Es Es NNP cord-015369-72cjogxz 630 2 erfolgte erfolgte NN cord-015369-72cjogxz 630 3 die die VBP cord-015369-72cjogxz 630 4 Unterteilung Unterteilung NNP cord-015369-72cjogxz 630 5 in in IN cord-015369-72cjogxz 630 6 vier vier NNP cord-015369-72cjogxz 630 7 Gruppen Gruppen NNP cord-015369-72cjogxz 630 8 und und IN cord-015369-72cjogxz 630 9 4 4 CD cord-015369-72cjogxz 630 10 Zeitpunkten Zeitpunkten NNP cord-015369-72cjogxz 630 11 , , , cord-015369-72cjogxz 630 12 wobei wobei JJ cord-015369-72cjogxz 630 13 die die VBP cord-015369-72cjogxz 630 14 Applikation Applikation NNP cord-015369-72cjogxz 630 15 von von NNP cord-015369-72cjogxz 630 16 unverkapseltem unverkapseltem NNP cord-015369-72cjogxz 630 17 und und NNP cord-015369-72cjogxz 630 18 verkapseltem verkapseltem NNP cord-015369-72cjogxz 630 19 5-FU 5-fu CD cord-015369-72cjogxz 630 20 systemisch systemisch NNP cord-015369-72cjogxz 630 21 und und NNP cord-015369-72cjogxz 630 22 lokal lokal NNP cord-015369-72cjogxz 630 23 via via IN cord-015369-72cjogxz 630 24 Arteria Arteria NNP cord-015369-72cjogxz 630 25 hepatica hepatica NNP cord-015369-72cjogxz 630 26 erfolgte erfolgte NN cord-015369-72cjogxz 630 27 . . . cord-015369-72cjogxz 631 1 Tumorgewebskonzentrationen Tumorgewebskonzentrationen NNP cord-015369-72cjogxz 631 2 wurden wurden VBD cord-015369-72cjogxz 631 3 mittels mittels NNP cord-015369-72cjogxz 631 4 HPLC HPLC NNP cord-015369-72cjogxz 631 5 ( ( -LRB- cord-015369-72cjogxz 631 6 high high JJ cord-015369-72cjogxz 631 7 performance performance NN cord-015369-72cjogxz 631 8 liquid liquid NN cord-015369-72cjogxz 631 9 chromatography chromatography NN cord-015369-72cjogxz 631 10 ) ) -RRB- cord-015369-72cjogxz 631 11 bestimmt bestimmt NNP cord-015369-72cjogxz 631 12 . . . cord-015369-72cjogxz 632 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 632 2 . . . cord-015369-72cjogxz 633 1 Es Es NNP cord-015369-72cjogxz 633 2 konnte konnte NNP cord-015369-72cjogxz 634 1 eine eine NNP cord-015369-72cjogxz 634 2 ausreichende ausreichende NNP cord-015369-72cjogxz 635 1 Beladung Beladung NNP cord-015369-72cjogxz 635 2 der der NNP cord-015369-72cjogxz 635 3 Erythrozyten Erythrozyten NNP cord-015369-72cjogxz 635 4 mit mit NNP cord-015369-72cjogxz 635 5 5-FU 5-fu CD cord-015369-72cjogxz 635 6 erreicht erreicht NNP cord-015369-72cjogxz 635 7 werden werden NNP cord-015369-72cjogxz 635 8 . . . cord-015369-72cjogxz 636 1 Der Der NNP cord-015369-72cjogxz 636 2 Nachweis Nachweis NNP cord-015369-72cjogxz 636 3 gelang gelang NNP cord-015369-72cjogxz 637 1 durch durch NNP cord-015369-72cjogxz 637 2 Zentrifugieren Zentrifugieren NNP cord-015369-72cjogxz 637 3 der der NN cord-015369-72cjogxz 637 4 Erythrozyten Erythrozyten NNP cord-015369-72cjogxz 638 1 und und IN cord-015369-72cjogxz 638 2 anschließender anschließender NNP cord-015369-72cjogxz 638 3 Lyse lyse VBP cord-015369-72cjogxz 638 4 der der NNP cord-015369-72cjogxz 638 5 Erythrozytenmembranen Erythrozytenmembranen NNP cord-015369-72cjogxz 638 6 . . . cord-015369-72cjogxz 639 1 Der Der NNP cord-015369-72cjogxz 639 2 Ü Ü NNP cord-015369-72cjogxz 639 3 berstand berstand NN cord-015369-72cjogxz 639 4 wurde wurde NNP cord-015369-72cjogxz 639 5 dann dann NNP cord-015369-72cjogxz 639 6 per per IN cord-015369-72cjogxz 639 7 HPLC HPLC NNP cord-015369-72cjogxz 639 8 gemessen gemessen NNP cord-015369-72cjogxz 639 9 . . . cord-015369-72cjogxz 640 1 Die die VB cord-015369-72cjogxz 640 2 Tumorkonzentration tumorkonzentration NN cord-015369-72cjogxz 640 3 war war NN cord-015369-72cjogxz 640 4 signifikant signifikant NN cord-015369-72cjogxz 640 5 ( ( -LRB- cord-015369-72cjogxz 640 6 p p NN cord-015369-72cjogxz 640 7 < < XX cord-015369-72cjogxz 640 8 0,01 0,01 NN cord-015369-72cjogxz 640 9 ) ) -RRB- cord-015369-72cjogxz 641 1 gesteigert gesteigert NNP cord-015369-72cjogxz 641 2 durch durch NNP cord-015369-72cjogxz 641 3 die die VBP cord-015369-72cjogxz 642 1 Verkapselung Verkapselung NNP cord-015369-72cjogxz 642 2 in in IN cord-015369-72cjogxz 642 3 Erythrozyten Erythrozyten NNP cord-015369-72cjogxz 642 4 sowie sowie NNP cord-015369-72cjogxz 642 5 durch durch NNP cord-015369-72cjogxz 642 6 lokoregionäre lokoregionäre NNP cord-015369-72cjogxz 642 7 Applikation Applikation NNP cord-015369-72cjogxz 642 8 . . . cord-015369-72cjogxz 643 1 Die die VB cord-015369-72cjogxz 643 2 Tumorkonzentration tumorkonzentration NN cord-015369-72cjogxz 643 3 wurde wurde NN cord-015369-72cjogxz 643 4 als als NN cord-015369-72cjogxz 643 5 Konzentrationszeitkurve Konzentrationszeitkurve NNP cord-015369-72cjogxz 643 6 ( ( -LRB- cord-015369-72cjogxz 643 7 Area area NN cord-015369-72cjogxz 643 8 under under IN cord-015369-72cjogxz 643 9 the the DT cord-015369-72cjogxz 643 10 curve curve NN cord-015369-72cjogxz 643 11 AUC AUC NNP cord-015369-72cjogxz 643 12 ) ) -RRB- cord-015369-72cjogxz 644 1 vom vom NNP cord-015369-72cjogxz 644 2 Zeitpunkt Zeitpunkt NNP cord-015369-72cjogxz 644 3 12 12 CD cord-015369-72cjogxz 644 4 - - SYM cord-015369-72cjogxz 644 5 44 44 CD cord-015369-72cjogxz 644 6 h h NN cord-015369-72cjogxz 644 7 dargestellt dargestellt NNP cord-015369-72cjogxz 644 8 . . . cord-015369-72cjogxz 645 1 freíes freíes NNP cord-015369-72cjogxz 645 2 5-FU 5-fu CD cord-015369-72cjogxz 645 3 5-FU 5-fu CD cord-015369-72cjogxz 645 4 verkapselt verkapselt NNS cord-015369-72cjogxz 646 1 86,6 86,6 CD cord-015369-72cjogxz 647 1 mg mg NNP cord-015369-72cjogxz 647 2 / / SYM cord-015369-72cjogxz 647 3 ml ml NNP cord-015369-72cjogxz 648 1 Á á NN cord-015369-72cjogxz 648 2 min min NN cord-015369-72cjogxz 649 1 126,3 126,3 CD cord-015369-72cjogxz 649 2 mg mg NNP cord-015369-72cjogxz 649 3 / / SYM cord-015369-72cjogxz 649 4 ml ml NN cord-015369-72cjogxz 649 5 Á á NN cord-015369-72cjogxz 649 6 min min NN cord-015369-72cjogxz 649 7 systemische systemische JJ cord-015369-72cjogxz 649 8 Appl Appl NNP cord-015369-72cjogxz 649 9 . . . cord-015369-72cjogxz 650 1 338,3 338,3 CD cord-015369-72cjogxz 650 2 mg mg NNP cord-015369-72cjogxz 650 3 / / SYM cord-015369-72cjogxz 650 4 ml ml NN cord-015369-72cjogxz 651 1 Á á NN cord-015369-72cjogxz 651 2 min min NN cord-015369-72cjogxz 652 1 411,8 411,8 CD cord-015369-72cjogxz 653 1 mg mg NNP cord-015369-72cjogxz 654 1 /ml /ml NFP cord-015369-72cjogxz 654 2 Á á NN cord-015369-72cjogxz 654 3 min min NN cord-015369-72cjogxz 654 4 arterielle arterielle NN cord-015369-72cjogxz 654 5 Appl Appl NNP cord-015369-72cjogxz 654 6 . . . cord-015369-72cjogxz 655 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 655 2 . . . cord-015369-72cjogxz 656 1 Die die VB cord-015369-72cjogxz 656 2 chemische chemische NN cord-015369-72cjogxz 656 3 Verkapselung Verkapselung NNP cord-015369-72cjogxz 656 4 von von NNP cord-015369-72cjogxz 656 5 5-FU 5-fu CD cord-015369-72cjogxz 656 6 in in IN cord-015369-72cjogxz 656 7 Erythrozyten Erythrozyten NNP cord-015369-72cjogxz 656 8 der der NNP cord-015369-72cjogxz 656 9 Ratte Ratte NNP cord-015369-72cjogxz 656 10 ist ist NN cord-015369-72cjogxz 656 11 möglich möglich NN cord-015369-72cjogxz 656 12 , , , cord-015369-72cjogxz 656 13 wobei wobei NNP cord-015369-72cjogxz 656 14 ein ein NNP cord-015369-72cjogxz 656 15 hoher hoher NNP cord-015369-72cjogxz 656 16 Grad Grad NNP cord-015369-72cjogxz 656 17 der der NNP cord-015369-72cjogxz 656 18 Beladung Beladung NNP cord-015369-72cjogxz 656 19 der der NNP cord-015369-72cjogxz 656 20 Erythrozyten Erythrozyten NNP cord-015369-72cjogxz 656 21 erreicht erreicht NN cord-015369-72cjogxz 656 22 werden werden NNP cord-015369-72cjogxz 656 23 kann kann NNP cord-015369-72cjogxz 656 24 . . . cord-015369-72cjogxz 657 1 Es Es NNP cord-015369-72cjogxz 657 2 zeigten zeigten NNP cord-015369-72cjogxz 657 3 sich sich NNP cord-015369-72cjogxz 657 4 signifikant signifikant NNP cord-015369-72cjogxz 657 5 höhere höhere NNP cord-015369-72cjogxz 657 6 5-FU 5-fu ADD cord-015369-72cjogxz 657 7 - - : cord-015369-72cjogxz 657 8 Tumorkonzentrationen Tumorkonzentrationen NNP cord-015369-72cjogxz 657 9 bei bei NNP cord-015369-72cjogxz 657 10 der der NNP cord-015369-72cjogxz 657 11 lokoregionären lokoregionären NNP cord-015369-72cjogxz 657 12 gegenüber gegenüber NNP cord-015369-72cjogxz 657 13 der der NNP cord-015369-72cjogxz 657 14 systemischen systemischen NNP cord-015369-72cjogxz 657 15 sowie sowie NNP cord-015369-72cjogxz 657 16 bei bei NNP cord-015369-72cjogxz 657 17 der der NNP cord-015369-72cjogxz 657 18 Verkapselung Verkapselung NNP cord-015369-72cjogxz 657 19 in in IN cord-015369-72cjogxz 657 20 Erythrozyten Erythrozyten NNP cord-015369-72cjogxz 657 21 . . . cord-015369-72cjogxz 658 1 Expression expression NN cord-015369-72cjogxz 658 2 of of IN cord-015369-72cjogxz 658 3 integrin integrin NN cord-015369-72cjogxz 658 4 - - HYPH cord-015369-72cjogxz 658 5 linked link VBN cord-015369-72cjogxz 658 6 kinase kinase NN cord-015369-72cjogxz 658 7 and and CC cord-015369-72cjogxz 658 8 the the DT cord-015369-72cjogxz 658 9 progression progression NN cord-015369-72cjogxz 658 10 of of IN cord-015369-72cjogxz 658 11 early early JJ cord-015369-72cjogxz 658 12 - - HYPH cord-015369-72cjogxz 658 13 stage stage NN cord-015369-72cjogxz 658 14 NSCLC NSCLC NNP cord-015369-72cjogxz 658 15 : : : cord-015369-72cjogxz 658 16 a a DT cord-015369-72cjogxz 658 17 pilot pilot NN cord-015369-72cjogxz 658 18 study study NN cord-015369-72cjogxz 658 19 Background Background NNP cord-015369-72cjogxz 658 20 . . . cord-015369-72cjogxz 659 1 Although although IN cord-015369-72cjogxz 659 2 radical radical JJ cord-015369-72cjogxz 659 3 resection resection NN cord-015369-72cjogxz 659 4 of of IN cord-015369-72cjogxz 659 5 early early JJ cord-015369-72cjogxz 659 6 - - HYPH cord-015369-72cjogxz 659 7 stage stage NN cord-015369-72cjogxz 659 8 nonsmall nonsmall NNP cord-015369-72cjogxz 659 9 cell cell NN cord-015369-72cjogxz 659 10 lung lung NN cord-015369-72cjogxz 659 11 cancer cancer NN cord-015369-72cjogxz 659 12 ( ( -LRB- cord-015369-72cjogxz 659 13 NSCLC NSCLC NNP cord-015369-72cjogxz 659 14 ) ) -RRB- cord-015369-72cjogxz 659 15 should should MD cord-015369-72cjogxz 659 16 warrant warrant VB cord-015369-72cjogxz 659 17 cure cure NN cord-015369-72cjogxz 659 18 in in IN cord-015369-72cjogxz 659 19 almost almost RB cord-015369-72cjogxz 659 20 every every DT cord-015369-72cjogxz 659 21 case case NN cord-015369-72cjogxz 659 22 , , , cord-015369-72cjogxz 659 23 clinical clinical JJ cord-015369-72cjogxz 659 24 experience experience NN cord-015369-72cjogxz 659 25 teaches teach VBZ cord-015369-72cjogxz 659 26 that that IN cord-015369-72cjogxz 659 27 recurrences recurrence NNS cord-015369-72cjogxz 659 28 appear appear VBP cord-015369-72cjogxz 659 29 in in IN cord-015369-72cjogxz 659 30 up up IN cord-015369-72cjogxz 659 31 to to TO cord-015369-72cjogxz 659 32 40 40 CD cord-015369-72cjogxz 659 33 % % NN cord-015369-72cjogxz 659 34 of of IN cord-015369-72cjogxz 659 35 cases case NNS cord-015369-72cjogxz 659 36 . . . cord-015369-72cjogxz 660 1 Therefore therefore RB cord-015369-72cjogxz 660 2 , , , cord-015369-72cjogxz 660 3 the the DT cord-015369-72cjogxz 660 4 prognosis prognosis NN cord-015369-72cjogxz 660 5 is be VBZ cord-015369-72cjogxz 660 6 probably probably RB cord-015369-72cjogxz 660 7 codetermined codetermine VBN cord-015369-72cjogxz 660 8 by by IN cord-015369-72cjogxz 660 9 additional additional JJ cord-015369-72cjogxz 660 10 risk risk NN cord-015369-72cjogxz 660 11 factors factor NNS cord-015369-72cjogxz 660 12 , , , cord-015369-72cjogxz 660 13 which which WDT cord-015369-72cjogxz 660 14 are be VBP cord-015369-72cjogxz 660 15 not not RB cord-015369-72cjogxz 660 16 described describe VBN cord-015369-72cjogxz 660 17 by by IN cord-015369-72cjogxz 660 18 the the DT cord-015369-72cjogxz 660 19 TNM TNM NNP cord-015369-72cjogxz 660 20 scheme scheme NN cord-015369-72cjogxz 660 21 . . . cord-015369-72cjogxz 661 1 Integrin Integrin NNP cord-015369-72cjogxz 661 2 - - HYPH cord-015369-72cjogxz 661 3 linked link VBN cord-015369-72cjogxz 661 4 kinase kinase NN cord-015369-72cjogxz 661 5 ( ( -LRB- cord-015369-72cjogxz 661 6 ILK ILK NNP cord-015369-72cjogxz 661 7 ) ) -RRB- cord-015369-72cjogxz 661 8 is be VBZ cord-015369-72cjogxz 661 9 a a DT cord-015369-72cjogxz 661 10 known know VBN cord-015369-72cjogxz 661 11 molecular molecular JJ cord-015369-72cjogxz 661 12 risk risk NN cord-015369-72cjogxz 661 13 factor factor NN cord-015369-72cjogxz 661 14 for for IN cord-015369-72cjogxz 661 15 metastatic metastatic JJ cord-015369-72cjogxz 661 16 progression progression NN cord-015369-72cjogxz 661 17 . . . cord-015369-72cjogxz 662 1 In in IN cord-015369-72cjogxz 662 2 this this DT cord-015369-72cjogxz 662 3 study study NN cord-015369-72cjogxz 662 4 we -PRON- PRP cord-015369-72cjogxz 662 5 attempt attempt VBP cord-015369-72cjogxz 662 6 to to TO cord-015369-72cjogxz 662 7 verify verify VB cord-015369-72cjogxz 662 8 its -PRON- PRP$ cord-015369-72cjogxz 662 9 role role NN cord-015369-72cjogxz 662 10 in in IN cord-015369-72cjogxz 662 11 the the DT cord-015369-72cjogxz 662 12 progression progression NN cord-015369-72cjogxz 662 13 of of IN cord-015369-72cjogxz 662 14 early early JJ cord-015369-72cjogxz 662 15 - - HYPH cord-015369-72cjogxz 662 16 stage stage NN cord-015369-72cjogxz 662 17 NSCLC NSCLC NNP cord-015369-72cjogxz 662 18 . . . cord-015369-72cjogxz 663 1 Methods method NNS cord-015369-72cjogxz 663 2 . . . cord-015369-72cjogxz 664 1 All all DT cord-015369-72cjogxz 664 2 stage stage NN cord-015369-72cjogxz 664 3 IA IA NNP cord-015369-72cjogxz 664 4 pulmonary pulmonary JJ cord-015369-72cjogxz 664 5 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 664 6 patients patient NNS cord-015369-72cjogxz 664 7 operated operate VBN cord-015369-72cjogxz 664 8 until until IN cord-015369-72cjogxz 664 9 2001 2001 CD cord-015369-72cjogxz 664 10 in in IN cord-015369-72cjogxz 664 11 our -PRON- PRP$ cord-015369-72cjogxz 664 12 institution institution NN cord-015369-72cjogxz 664 13 have have VBP cord-015369-72cjogxz 664 14 been be VBN cord-015369-72cjogxz 664 15 retrieved retrieve VBN cord-015369-72cjogxz 664 16 from from IN cord-015369-72cjogxz 664 17 the the DT cord-015369-72cjogxz 664 18 clinical clinical JJ cord-015369-72cjogxz 664 19 archive archive NN cord-015369-72cjogxz 664 20 , , , cord-015369-72cjogxz 664 21 and and CC cord-015369-72cjogxz 664 22 a a DT cord-015369-72cjogxz 664 23 follow follow NN cord-015369-72cjogxz 664 24 - - HYPH cord-015369-72cjogxz 664 25 up up NN cord-015369-72cjogxz 664 26 has have VBZ cord-015369-72cjogxz 664 27 been be VBN cord-015369-72cjogxz 664 28 conducted conduct VBN cord-015369-72cjogxz 664 29 . . . cord-015369-72cjogxz 665 1 The the DT cord-015369-72cjogxz 665 2 pathological pathological JJ cord-015369-72cjogxz 665 3 specimens specimen NNS cord-015369-72cjogxz 665 4 of of IN cord-015369-72cjogxz 665 5 the the DT cord-015369-72cjogxz 665 6 primary primary JJ cord-015369-72cjogxz 665 7 tumor tumor NN cord-015369-72cjogxz 665 8 have have VBP cord-015369-72cjogxz 665 9 been be VBN cord-015369-72cjogxz 665 10 stained stain VBN cord-015369-72cjogxz 665 11 against against IN cord-015369-72cjogxz 665 12 ILK ILK NNP cord-015369-72cjogxz 665 13 , , , cord-015369-72cjogxz 665 14 two two CD cord-015369-72cjogxz 665 15 blinded blind VBN cord-015369-72cjogxz 665 16 observers observer NNS cord-015369-72cjogxz 665 17 have have VBP cord-015369-72cjogxz 665 18 scored score VBN cord-015369-72cjogxz 665 19 the the DT cord-015369-72cjogxz 665 20 ILK ILK NNP cord-015369-72cjogxz 665 21 expression expression NN cord-015369-72cjogxz 665 22 . . . cord-015369-72cjogxz 666 1 The the DT cord-015369-72cjogxz 666 2 results result NNS cord-015369-72cjogxz 666 3 have have VBP cord-015369-72cjogxz 666 4 been be VBN cord-015369-72cjogxz 666 5 compared compare VBN cord-015369-72cjogxz 666 6 with with IN cord-015369-72cjogxz 666 7 the the DT cord-015369-72cjogxz 666 8 clinical clinical JJ cord-015369-72cjogxz 666 9 data datum NNS cord-015369-72cjogxz 666 10 adopting adopt VBG cord-015369-72cjogxz 666 11 a a DT cord-015369-72cjogxz 666 12 basic basic JJ cord-015369-72cjogxz 666 13 Kaplan Kaplan NNP cord-015369-72cjogxz 666 14 Meier Meier NNP cord-015369-72cjogxz 666 15 statistics statistic NNS cord-015369-72cjogxz 666 16 . . . cord-015369-72cjogxz 667 1 Results result NNS cord-015369-72cjogxz 667 2 . . . cord-015369-72cjogxz 668 1 We -PRON- PRP cord-015369-72cjogxz 668 2 examined examine VBD cord-015369-72cjogxz 668 3 a a DT cord-015369-72cjogxz 668 4 total total NN cord-015369-72cjogxz 668 5 of of IN cord-015369-72cjogxz 668 6 32 32 CD cord-015369-72cjogxz 668 7 patients patient NNS cord-015369-72cjogxz 668 8 ( ( -LRB- cord-015369-72cjogxz 668 9 20 20 CD cord-015369-72cjogxz 668 10 males male NNS cord-015369-72cjogxz 668 11 , , , cord-015369-72cjogxz 668 12 12 12 CD cord-015369-72cjogxz 668 13 females female NNS cord-015369-72cjogxz 668 14 ) ) -RRB- cord-015369-72cjogxz 668 15 with with IN cord-015369-72cjogxz 668 16 a a DT cord-015369-72cjogxz 668 17 mean mean JJ cord-015369-72cjogxz 668 18 age age NN cord-015369-72cjogxz 668 19 of of IN cord-015369-72cjogxz 668 20 62 62 CD cord-015369-72cjogxz 668 21 years year NNS cord-015369-72cjogxz 668 22 . . . cord-015369-72cjogxz 669 1 Median median JJ cord-015369-72cjogxz 669 2 follow follow NN cord-015369-72cjogxz 669 3 - - HYPH cord-015369-72cjogxz 669 4 up up NN cord-015369-72cjogxz 669 5 was be VBD cord-015369-72cjogxz 669 6 7.2 7.2 CD cord-015369-72cjogxz 669 7 years year NNS cord-015369-72cjogxz 669 8 . . . cord-015369-72cjogxz 670 1 Twenty twenty CD cord-015369-72cjogxz 670 2 - - HYPH cord-015369-72cjogxz 670 3 eight eight CD cord-015369-72cjogxz 670 4 patients patient NNS cord-015369-72cjogxz 670 5 ( ( -LRB- cord-015369-72cjogxz 670 6 88 88 CD cord-015369-72cjogxz 670 7 % % NN cord-015369-72cjogxz 670 8 ) ) -RRB- cord-015369-72cjogxz 670 9 were be VBD cord-015369-72cjogxz 670 10 ILK ilk NN cord-015369-72cjogxz 670 11 - - HYPH cord-015369-72cjogxz 670 12 positive positive JJ cord-015369-72cjogxz 670 13 , , , cord-015369-72cjogxz 670 14 only only RB cord-015369-72cjogxz 670 15 four four CD cord-015369-72cjogxz 670 16 ( ( -LRB- cord-015369-72cjogxz 670 17 12 12 CD cord-015369-72cjogxz 670 18 % % NN cord-015369-72cjogxz 670 19 ) ) -RRB- cord-015369-72cjogxz 670 20 were be VBD cord-015369-72cjogxz 670 21 ILK ilk NN cord-015369-72cjogxz 670 22 - - HYPH cord-015369-72cjogxz 670 23 negative negative JJ cord-015369-72cjogxz 670 24 . . . cord-015369-72cjogxz 671 1 Eleven eleven CD cord-015369-72cjogxz 671 2 ILK ilk NN cord-015369-72cjogxz 671 3 - - HYPH cord-015369-72cjogxz 671 4 positive positive JJ cord-015369-72cjogxz 671 5 patients patient NNS cord-015369-72cjogxz 671 6 experienced experience VBD cord-015369-72cjogxz 671 7 a a DT cord-015369-72cjogxz 671 8 recurrence recurrence NN cord-015369-72cjogxz 671 9 within within IN cord-015369-72cjogxz 671 10 five five CD cord-015369-72cjogxz 671 11 years year NNS cord-015369-72cjogxz 671 12 ; ; : cord-015369-72cjogxz 671 13 from from IN cord-015369-72cjogxz 671 14 those those DT cord-015369-72cjogxz 671 15 patients patient NNS cord-015369-72cjogxz 671 16 , , , cord-015369-72cjogxz 671 17 ten ten CD cord-015369-72cjogxz 671 18 died die VBD cord-015369-72cjogxz 671 19 . . . cord-015369-72cjogxz 672 1 This this DT cord-015369-72cjogxz 672 2 corresponds correspond VBZ cord-015369-72cjogxz 672 3 to to IN cord-015369-72cjogxz 672 4 a a DT cord-015369-72cjogxz 672 5 5-years 5-years CD cord-015369-72cjogxz 672 6 recurrence recurrence NN cord-015369-72cjogxz 672 7 - - HYPH cord-015369-72cjogxz 672 8 free free JJ cord-015369-72cjogxz 672 9 survival survival NN cord-015369-72cjogxz 672 10 of of IN cord-015369-72cjogxz 672 11 67 67 CD cord-015369-72cjogxz 672 12 AE AE NNP cord-015369-72cjogxz 672 13 9 9 CD cord-015369-72cjogxz 672 14 % % NN cord-015369-72cjogxz 672 15 and and CC cord-015369-72cjogxz 672 16 a a DT cord-015369-72cjogxz 672 17 5-years 5-years CD cord-015369-72cjogxz 672 18 overall overall JJ cord-015369-72cjogxz 672 19 survival survival NN cord-015369-72cjogxz 672 20 of of IN cord-015369-72cjogxz 672 21 74 74 CD cord-015369-72cjogxz 672 22 AE AE NNP cord-015369-72cjogxz 672 23 8 8 CD cord-015369-72cjogxz 672 24 % % NN cord-015369-72cjogxz 672 25 in in IN cord-015369-72cjogxz 672 26 ILK ilk NN cord-015369-72cjogxz 672 27 - - HYPH cord-015369-72cjogxz 672 28 positive positive JJ cord-015369-72cjogxz 672 29 cases case NNS cord-015369-72cjogxz 672 30 . . . cord-015369-72cjogxz 673 1 Conversely conversely RB cord-015369-72cjogxz 673 2 , , , cord-015369-72cjogxz 673 3 none none NN cord-015369-72cjogxz 673 4 of of IN cord-015369-72cjogxz 673 5 the the DT cord-015369-72cjogxz 673 6 ILKnegative ILKnegative NNP cord-015369-72cjogxz 673 7 patients patient NNS cord-015369-72cjogxz 673 8 had have VBD cord-015369-72cjogxz 673 9 a a DT cord-015369-72cjogxz 673 10 recurrence recurrence NN cord-015369-72cjogxz 673 11 nor nor CC cord-015369-72cjogxz 673 12 died die VBD cord-015369-72cjogxz 673 13 within within IN cord-015369-72cjogxz 673 14 five five CD cord-015369-72cjogxz 673 15 years year NNS cord-015369-72cjogxz 673 16 . . . cord-015369-72cjogxz 674 1 Conclusions conclusion NNS cord-015369-72cjogxz 674 2 . . . cord-015369-72cjogxz 675 1 ILK ilk NN cord-015369-72cjogxz 675 2 - - HYPH cord-015369-72cjogxz 675 3 negative negative JJ cord-015369-72cjogxz 675 4 stage stage NN cord-015369-72cjogxz 676 1 IA IA NNP cord-015369-72cjogxz 676 2 NSCLC NSCLC NNP cord-015369-72cjogxz 676 3 patients patient NNS cord-015369-72cjogxz 676 4 have have VBP cord-015369-72cjogxz 676 5 apparently apparently RB cord-015369-72cjogxz 676 6 a a DT cord-015369-72cjogxz 676 7 better well JJR cord-015369-72cjogxz 676 8 tumor tumor NN cord-015369-72cjogxz 676 9 - - HYPH cord-015369-72cjogxz 676 10 related relate VBN cord-015369-72cjogxz 676 11 prognosis prognosis NN cord-015369-72cjogxz 676 12 than than IN cord-015369-72cjogxz 676 13 ILK ilk NN cord-015369-72cjogxz 676 14 - - HYPH cord-015369-72cjogxz 676 15 positive positive JJ cord-015369-72cjogxz 676 16 patients patient NNS cord-015369-72cjogxz 676 17 . . . cord-015369-72cjogxz 677 1 However however RB cord-015369-72cjogxz 677 2 , , , cord-015369-72cjogxz 677 3 these these DT cord-015369-72cjogxz 677 4 observations observation NNS cord-015369-72cjogxz 677 5 have have VBP cord-015369-72cjogxz 677 6 to to TO cord-015369-72cjogxz 677 7 be be VB cord-015369-72cjogxz 677 8 extended extend VBN cord-015369-72cjogxz 677 9 unto unto IN cord-015369-72cjogxz 677 10 a a DT cord-015369-72cjogxz 677 11 larger large JJR cord-015369-72cjogxz 677 12 patient patient JJ cord-015369-72cjogxz 677 13 cohort cohort NN cord-015369-72cjogxz 677 14 . . . cord-015369-72cjogxz 678 1 Biliverdin Biliverdin NNP cord-015369-72cjogxz 678 2 reductase reductase NN cord-015369-72cjogxz 678 3 : : : cord-015369-72cjogxz 679 1 a a DT cord-015369-72cjogxz 679 2 crucial crucial JJ cord-015369-72cjogxz 679 3 enzyme enzyme NN cord-015369-72cjogxz 679 4 in in IN cord-015369-72cjogxz 679 5 bile bile NN cord-015369-72cjogxz 679 6 pigment pigment NN cord-015369-72cjogxz 679 7 mediated mediate VBN cord-015369-72cjogxz 679 8 tumor tumor NN cord-015369-72cjogxz 679 9 inhibition inhibition NN cord-015369-72cjogxz 679 10 ? ? . cord-015369-72cjogxz 680 1 Background background NN cord-015369-72cjogxz 680 2 . . . cord-015369-72cjogxz 681 1 Maximization maximization NN cord-015369-72cjogxz 681 2 of of IN cord-015369-72cjogxz 681 3 liver liver NN cord-015369-72cjogxz 681 4 regeneration regeneration NN cord-015369-72cjogxz 681 5 represents represent VBZ cord-015369-72cjogxz 681 6 a a DT cord-015369-72cjogxz 681 7 promising promising JJ cord-015369-72cjogxz 681 8 strategy strategy NN cord-015369-72cjogxz 681 9 to to TO cord-015369-72cjogxz 681 10 improve improve VB cord-015369-72cjogxz 681 11 outcomes outcome NNS cord-015369-72cjogxz 681 12 after after IN cord-015369-72cjogxz 681 13 extensive extensive JJ cord-015369-72cjogxz 681 14 liver liver NN cord-015369-72cjogxz 681 15 resection resection NN cord-015369-72cjogxz 681 16 . . . cord-015369-72cjogxz 682 1 Here here RB cord-015369-72cjogxz 682 2 , , , cord-015369-72cjogxz 682 3 we -PRON- PRP cord-015369-72cjogxz 682 4 investigate investigate VBP cord-015369-72cjogxz 682 5 the the DT cord-015369-72cjogxz 682 6 role role NN cord-015369-72cjogxz 682 7 of of IN cord-015369-72cjogxz 682 8 lipocalin lipocalin NN cord-015369-72cjogxz 682 9 2 2 CD cord-015369-72cjogxz 682 10 in in IN cord-015369-72cjogxz 682 11 liver liver NN cord-015369-72cjogxz 682 12 regeneration regeneration NN cord-015369-72cjogxz 682 13 . . . cord-015369-72cjogxz 683 1 Methods method NNS cord-015369-72cjogxz 683 2 . . . cord-015369-72cjogxz 684 1 Lcn2 Lcn2 NNP cord-015369-72cjogxz 684 2 þ þ NNP cord-015369-72cjogxz 685 1 = = NFP cord-015369-72cjogxz 685 2 þ þ NNP cord-015369-72cjogxz 685 3 , , , cord-015369-72cjogxz 685 4 lcn2 lcn2 NNP cord-015369-72cjogxz 685 5 þ þ NNP cord-015369-72cjogxz 685 6 = = SYM cord-015369-72cjogxz 685 7 À à NN cord-015369-72cjogxz 685 8 and and CC cord-015369-72cjogxz 685 9 lcn2 lcn2 NN cord-015369-72cjogxz 685 10 À à NN cord-015369-72cjogxz 685 11 = = SYM cord-015369-72cjogxz 685 12 À à NN cord-015369-72cjogxz 685 13 mice mouse NNS cord-015369-72cjogxz 685 14 were be VBD cord-015369-72cjogxz 685 15 subjected subject VBN cord-015369-72cjogxz 685 16 to to IN cord-015369-72cjogxz 685 17 2/3 2/3 CD cord-015369-72cjogxz 685 18 partial partial JJ cord-015369-72cjogxz 685 19 hepatectomy hepatectomy NN cord-015369-72cjogxz 685 20 . . . cord-015369-72cjogxz 686 1 Hepatic hepatic JJ cord-015369-72cjogxz 686 2 proliferation proliferation NN cord-015369-72cjogxz 686 3 was be VBD cord-015369-72cjogxz 686 4 measured measure VBN cord-015369-72cjogxz 686 5 by by IN cord-015369-72cjogxz 686 6 BrdU BrdU NNP cord-015369-72cjogxz 686 7 and and CC cord-015369-72cjogxz 686 8 PCNA PCNA NNP cord-015369-72cjogxz 686 9 immunohistochemistry immunohistochemistry NN cord-015369-72cjogxz 686 10 . . . cord-015369-72cjogxz 687 1 Hepatic hepatic JJ cord-015369-72cjogxz 687 2 Lcn2 Lcn2 NNP cord-015369-72cjogxz 687 3 expression expression NN cord-015369-72cjogxz 687 4 was be VBD cord-015369-72cjogxz 687 5 analyzed analyze VBN cord-015369-72cjogxz 687 6 by by IN cord-015369-72cjogxz 687 7 qRT qRT NNP cord-015369-72cjogxz 687 8 - - HYPH cord-015369-72cjogxz 687 9 PCR PCR NNP cord-015369-72cjogxz 687 10 and and CC cord-015369-72cjogxz 687 11 western western JJ cord-015369-72cjogxz 687 12 blots blot NNS cord-015369-72cjogxz 687 13 . . . cord-015369-72cjogxz 688 1 Serum serum NN cord-015369-72cjogxz 688 2 levels level NNS cord-015369-72cjogxz 688 3 of of IN cord-015369-72cjogxz 688 4 Lcn2 Lcn2 NNP cord-015369-72cjogxz 688 5 , , , cord-015369-72cjogxz 688 6 IL-6 IL-6 NNP cord-015369-72cjogxz 688 7 , , , cord-015369-72cjogxz 688 8 and and CC cord-015369-72cjogxz 688 9 TNF TNF NNP cord-015369-72cjogxz 688 10 - - , cord-015369-72cjogxz 688 11 were be VBD cord-015369-72cjogxz 688 12 determined determine VBN cord-015369-72cjogxz 688 13 by by IN cord-015369-72cjogxz 688 14 ELISA ELISA NNP cord-015369-72cjogxz 688 15 . . . cord-015369-72cjogxz 689 1 Results result NNS cord-015369-72cjogxz 689 2 . . . cord-015369-72cjogxz 690 1 Hepatic hepatic JJ cord-015369-72cjogxz 690 2 regeneration regeneration NN cord-015369-72cjogxz 690 3 in in IN cord-015369-72cjogxz 690 4 lcn2 lcn2 NN cord-015369-72cjogxz 691 1 þ þ NNP cord-015369-72cjogxz 692 1 = = NFP cord-015369-72cjogxz 692 2 þ þ CD cord-015369-72cjogxz 692 3 mice mouse NNS cord-015369-72cjogxz 692 4 was be VBD cord-015369-72cjogxz 692 5 analyzed analyze VBN cord-015369-72cjogxz 692 6 at at IN cord-015369-72cjogxz 692 7 24 24 CD cord-015369-72cjogxz 692 8 , , , cord-015369-72cjogxz 692 9 48 48 CD cord-015369-72cjogxz 692 10 , , , cord-015369-72cjogxz 692 11 72 72 CD cord-015369-72cjogxz 692 12 and and CC cord-015369-72cjogxz 692 13 96 96 CD cord-015369-72cjogxz 692 14 h h NN cord-015369-72cjogxz 692 15 after after IN cord-015369-72cjogxz 692 16 partial partial JJ cord-015369-72cjogxz 692 17 hepatectomy hepatectomy NN cord-015369-72cjogxz 692 18 . . . cord-015369-72cjogxz 693 1 The the DT cord-015369-72cjogxz 693 2 peak peak NN cord-015369-72cjogxz 693 3 of of IN cord-015369-72cjogxz 693 4 hepatic hepatic JJ cord-015369-72cjogxz 693 5 proliferation proliferation NN cord-015369-72cjogxz 693 6 as as IN cord-015369-72cjogxz 693 7 indicated indicate VBN cord-015369-72cjogxz 693 8 by by IN cord-015369-72cjogxz 693 9 the the DT cord-015369-72cjogxz 693 10 number number NN cord-015369-72cjogxz 693 11 of of IN cord-015369-72cjogxz 693 12 BrdU BrdU NNP cord-015369-72cjogxz 693 13 - - HYPH cord-015369-72cjogxz 693 14 and and CC cord-015369-72cjogxz 693 15 PCNA PCNA NNP cord-015369-72cjogxz 693 16 - - HYPH cord-015369-72cjogxz 693 17 positive positive JJ cord-015369-72cjogxz 693 18 cells cell NNS cord-015369-72cjogxz 693 19 was be VBD cord-015369-72cjogxz 693 20 confirmed confirm VBN cord-015369-72cjogxz 693 21 to to TO cord-015369-72cjogxz 693 22 be be VB cord-015369-72cjogxz 693 23 at at IN cord-015369-72cjogxz 693 24 48 48 CD cord-015369-72cjogxz 693 25 h h NN cord-015369-72cjogxz 693 26 post post NN cord-015369-72cjogxz 693 27 surgery surgery NN cord-015369-72cjogxz 693 28 . . . cord-015369-72cjogxz 694 1 Analysis analysis NN cord-015369-72cjogxz 694 2 of of IN cord-015369-72cjogxz 694 3 hepatic hepatic JJ cord-015369-72cjogxz 694 4 Lcn2 Lcn2 NNP cord-015369-72cjogxz 694 5 expression expression NN cord-015369-72cjogxz 694 6 showed show VBD cord-015369-72cjogxz 694 7 a a DT cord-015369-72cjogxz 694 8 140-fold 140-fold CD cord-015369-72cjogxz 694 9 upregulation upregulation NN cord-015369-72cjogxz 694 10 only only RB cord-015369-72cjogxz 694 11 24 24 CD cord-015369-72cjogxz 694 12 h h NN cord-015369-72cjogxz 694 13 after after IN cord-015369-72cjogxz 694 14 liver liver NN cord-015369-72cjogxz 694 15 resection resection NN cord-015369-72cjogxz 694 16 in in IN cord-015369-72cjogxz 694 17 lcn2 lcn2 NNP cord-015369-72cjogxz 694 18 þ þ NNP cord-015369-72cjogxz 694 19 = = NFP cord-015369-72cjogxz 694 20 þ þ CD cord-015369-72cjogxz 694 21 animals animal NNS cord-015369-72cjogxz 694 22 with with IN cord-015369-72cjogxz 694 23 a a DT cord-015369-72cjogxz 694 24 stepwise stepwise JJ cord-015369-72cjogxz 694 25 reduction reduction NN cord-015369-72cjogxz 694 26 during during IN cord-015369-72cjogxz 694 27 the the DT cord-015369-72cjogxz 694 28 observation observation NN cord-015369-72cjogxz 694 29 period period NN cord-015369-72cjogxz 694 30 ( ( -LRB- cord-015369-72cjogxz 694 31 48 48 CD cord-015369-72cjogxz 694 32 h h NN cord-015369-72cjogxz 694 33 15.7-fold 15.7-fold CD cord-015369-72cjogxz 694 34 , , , cord-015369-72cjogxz 694 35 72 72 CD cord-015369-72cjogxz 694 36 h h NN cord-015369-72cjogxz 694 37 5.5-fold 5.5-fold CD cord-015369-72cjogxz 694 38 , , , cord-015369-72cjogxz 694 39 96 96 CD cord-015369-72cjogxz 694 40 h h NN cord-015369-72cjogxz 694 41 5.8-fold 5.8-fold CD cord-015369-72cjogxz 694 42 ) ) -RRB- cord-015369-72cjogxz 694 43 . . . cord-015369-72cjogxz 695 1 Western western JJ cord-015369-72cjogxz 695 2 blots blot NNS cord-015369-72cjogxz 695 3 confirmed confirm VBD cord-015369-72cjogxz 695 4 significant significant JJ cord-015369-72cjogxz 695 5 Lcn2 Lcn2 NNP cord-015369-72cjogxz 695 6 protein protein NN cord-015369-72cjogxz 695 7 over over IN cord-015369-72cjogxz 695 8 - - HYPH cord-015369-72cjogxz 695 9 expression expression NN cord-015369-72cjogxz 695 10 24 24 CD cord-015369-72cjogxz 695 11 h h NN cord-015369-72cjogxz 695 12 after after IN cord-015369-72cjogxz 695 13 partial partial JJ cord-015369-72cjogxz 695 14 hepatectomy hepatectomy NN cord-015369-72cjogxz 695 15 . . . cord-015369-72cjogxz 696 1 Also also RB cord-015369-72cjogxz 696 2 , , , cord-015369-72cjogxz 696 3 serum serum NN cord-015369-72cjogxz 696 4 Lcn2 lcn2 JJ cord-015369-72cjogxz 696 5 levels level NNS cord-015369-72cjogxz 696 6 were be VBD cord-015369-72cjogxz 696 7 significantly significantly RB cord-015369-72cjogxz 696 8 elevated elevate VBN cord-015369-72cjogxz 696 9 upon upon IN cord-015369-72cjogxz 696 10 liver liver NN cord-015369-72cjogxz 696 11 resection resection NN cord-015369-72cjogxz 696 12 . . . cord-015369-72cjogxz 697 1 To to TO cord-015369-72cjogxz 697 2 determine determine VB cord-015369-72cjogxz 697 3 the the DT cord-015369-72cjogxz 697 4 biological biological JJ cord-015369-72cjogxz 697 5 relevance relevance NN cord-015369-72cjogxz 697 6 of of IN cord-015369-72cjogxz 697 7 Lcn2 Lcn2 NNP cord-015369-72cjogxz 697 8 induction induction NN cord-015369-72cjogxz 697 9 on on IN cord-015369-72cjogxz 697 10 liver liver NN cord-015369-72cjogxz 697 11 regeneration regeneration NN cord-015369-72cjogxz 697 12 , , , cord-015369-72cjogxz 697 13 hepatocyte hepatocyte NN cord-015369-72cjogxz 697 14 proliferation proliferation NN cord-015369-72cjogxz 697 15 was be VBD cord-015369-72cjogxz 697 16 analyzed analyze VBN cord-015369-72cjogxz 697 17 in in IN cord-015369-72cjogxz 697 18 lcn2 lcn2 NNP cord-015369-72cjogxz 697 19 þ þ NNP cord-015369-72cjogxz 697 20 = = SYM cord-015369-72cjogxz 697 21 À à NN cord-015369-72cjogxz 697 22 and and CC cord-015369-72cjogxz 697 23 lcn2 lcn2 NN cord-015369-72cjogxz 697 24 À à NN cord-015369-72cjogxz 697 25 = = SYM cord-015369-72cjogxz 697 26 À à NN cord-015369-72cjogxz 697 27 mice mice NN cord-015369-72cjogxz 697 28 48 48 CD cord-015369-72cjogxz 697 29 h h NN cord-015369-72cjogxz 697 30 after after IN cord-015369-72cjogxz 697 31 partial partial JJ cord-015369-72cjogxz 697 32 hepatectomy hepatectomy NN cord-015369-72cjogxz 697 33 . . . cord-015369-72cjogxz 698 1 The the DT cord-015369-72cjogxz 698 2 number number NN cord-015369-72cjogxz 698 3 of of IN cord-015369-72cjogxz 698 4 BrdU BrdU NNP cord-015369-72cjogxz 698 5 - - HYPH cord-015369-72cjogxz 698 6 and and CC cord-015369-72cjogxz 698 7 PCNA PCNA NNP cord-015369-72cjogxz 698 8 - - HYPH cord-015369-72cjogxz 698 9 positive positive JJ cord-015369-72cjogxz 698 10 cells cell NNS cord-015369-72cjogxz 698 11 did do VBD cord-015369-72cjogxz 698 12 not not RB cord-015369-72cjogxz 698 13 differ differ VB cord-015369-72cjogxz 698 14 significantly significantly RB cord-015369-72cjogxz 698 15 between between IN cord-015369-72cjogxz 698 16 the the DT cord-015369-72cjogxz 698 17 groups group NNS cord-015369-72cjogxz 698 18 . . . cord-015369-72cjogxz 699 1 However however RB cord-015369-72cjogxz 699 2 , , , cord-015369-72cjogxz 699 3 lcn2 lcn2 NN cord-015369-72cjogxz 699 4 À à NN cord-015369-72cjogxz 699 5 = = SYM cord-015369-72cjogxz 699 6 À à NN cord-015369-72cjogxz 699 7 animals animal NNS cord-015369-72cjogxz 699 8 exhibited exhibit VBD cord-015369-72cjogxz 699 9 a a DT cord-015369-72cjogxz 699 10 significantly significantly RB cord-015369-72cjogxz 699 11 elevated elevate VBN cord-015369-72cjogxz 699 12 baseline baseline JJ cord-015369-72cjogxz 699 13 liver liver NN cord-015369-72cjogxz 699 14 regeneration regeneration NN cord-015369-72cjogxz 699 15 ( ( -LRB- cord-015369-72cjogxz 699 16 6.6-fold 6.6-fold CD cord-015369-72cjogxz 699 17 lcn2 lcn2 NN cord-015369-72cjogxz 699 18 À à NN cord-015369-72cjogxz 699 19 = = FW cord-015369-72cjogxz 699 20 À à FW cord-015369-72cjogxz 699 21 vs vs IN cord-015369-72cjogxz 699 22 lcn2 lcn2 NNP cord-015369-72cjogxz 699 23 þ þ NNP cord-015369-72cjogxz 699 24 = = SYM cord-015369-72cjogxz 699 25 þ þ NNP cord-015369-72cjogxz 699 26 , , , cord-015369-72cjogxz 699 27 p p NN cord-015369-72cjogxz 699 28 < < XX cord-015369-72cjogxz 699 29 0.05 0.05 CD cord-015369-72cjogxz 699 30 ) ) -RRB- cord-015369-72cjogxz 699 31 . . . cord-015369-72cjogxz 700 1 Conclusions conclusion NNS cord-015369-72cjogxz 700 2 . . . cord-015369-72cjogxz 701 1 Up up IN cord-015369-72cjogxz 701 2 - - HYPH cord-015369-72cjogxz 701 3 regulation regulation NN cord-015369-72cjogxz 701 4 of of IN cord-015369-72cjogxz 701 5 Lcn2 Lcn2 NNP cord-015369-72cjogxz 701 6 after after IN cord-015369-72cjogxz 701 7 murine murine JJ cord-015369-72cjogxz 701 8 partial partial JJ cord-015369-72cjogxz 701 9 hepatectomy hepatectomy NN cord-015369-72cjogxz 701 10 is be VBZ cord-015369-72cjogxz 701 11 striking strike VBG cord-015369-72cjogxz 701 12 but but CC cord-015369-72cjogxz 701 13 without without IN cord-015369-72cjogxz 701 14 significant significant JJ cord-015369-72cjogxz 701 15 impact impact NN cord-015369-72cjogxz 701 16 on on IN cord-015369-72cjogxz 701 17 hepatocyte hepatocyte NN cord-015369-72cjogxz 701 18 proliferation proliferation NN cord-015369-72cjogxz 701 19 . . . cord-015369-72cjogxz 702 1 Our -PRON- PRP$ cord-015369-72cjogxz 702 2 results result NNS cord-015369-72cjogxz 702 3 imply imply VBP cord-015369-72cjogxz 702 4 that that IN cord-015369-72cjogxz 702 5 Lcn2 Lcn2 NNP cord-015369-72cjogxz 702 6 induction induction NN cord-015369-72cjogxz 702 7 upon upon IN cord-015369-72cjogxz 702 8 liver liver NN cord-015369-72cjogxz 702 9 resection resection NN cord-015369-72cjogxz 702 10 either either CC cord-015369-72cjogxz 702 11 constitutes constitute VBZ cord-015369-72cjogxz 702 12 a a DT cord-015369-72cjogxz 702 13 redundant redundant JJ cord-015369-72cjogxz 702 14 pathway pathway NN cord-015369-72cjogxz 702 15 or or CC cord-015369-72cjogxz 702 16 simply simply RB cord-015369-72cjogxz 702 17 displays display VBZ cord-015369-72cjogxz 702 18 an an DT cord-015369-72cjogxz 702 19 epiphenomenon epiphenomenon NN cord-015369-72cjogxz 702 20 . . . cord-015369-72cjogxz 703 1 Effect effect NN cord-015369-72cjogxz 703 2 of of IN cord-015369-72cjogxz 703 3 the the DT cord-015369-72cjogxz 703 4 probiotic probiotic JJ cord-015369-72cjogxz 703 5 mixture mixture NN cord-015369-72cjogxz 703 6 VSL#3 VSL#3 NNP cord-015369-72cjogxz 703 7 on on IN cord-015369-72cjogxz 703 8 epithelial epithelial JJ cord-015369-72cjogxz 703 9 barrier barrier NN cord-015369-72cjogxz 703 10 function function NN cord-015369-72cjogxz 703 11 , , , cord-015369-72cjogxz 703 12 tight tight JJ cord-015369-72cjogxz 703 13 junction junction NN cord-015369-72cjogxz 703 14 protein protein NN cord-015369-72cjogxz 703 15 expression expression NN cord-015369-72cjogxz 703 16 , , , cord-015369-72cjogxz 703 17 and and CC cord-015369-72cjogxz 703 18 apoptotic apoptotic JJ cord-015369-72cjogxz 703 19 ratio ratio NN cord-015369-72cjogxz 703 20 in in IN cord-015369-72cjogxz 703 21 a a DT cord-015369-72cjogxz 703 22 murine murine JJ cord-015369-72cjogxz 703 23 model model NN cord-015369-72cjogxz 703 24 of of IN cord-015369-72cjogxz 703 25 colitis colitis NN cord-015369-72cjogxz 703 26 Background Background NNP cord-015369-72cjogxz 703 27 . . . cord-015369-72cjogxz 704 1 Changes change NNS cord-015369-72cjogxz 704 2 in in IN cord-015369-72cjogxz 704 3 epithelial epithelial JJ cord-015369-72cjogxz 704 4 tight tight JJ cord-015369-72cjogxz 704 5 junction junction NN cord-015369-72cjogxz 704 6 protein protein NN cord-015369-72cjogxz 704 7 expression expression NN cord-015369-72cjogxz 704 8 and and CC cord-015369-72cjogxz 704 9 apoptosis apoptosis NN cord-015369-72cjogxz 704 10 increase increase VBP cord-015369-72cjogxz 704 11 epithelial epithelial JJ cord-015369-72cjogxz 704 12 permeability permeability NN cord-015369-72cjogxz 704 13 in in IN cord-015369-72cjogxz 704 14 inflammatory inflammatory JJ cord-015369-72cjogxz 704 15 bowel bowel NN cord-015369-72cjogxz 704 16 diseases disease NNS cord-015369-72cjogxz 704 17 . . . cord-015369-72cjogxz 705 1 The the DT cord-015369-72cjogxz 705 2 effect effect NN cord-015369-72cjogxz 705 3 of of IN cord-015369-72cjogxz 705 4 the the DT cord-015369-72cjogxz 705 5 probiotic probiotic JJ cord-015369-72cjogxz 705 6 mixture mixture NN cord-015369-72cjogxz 705 7 VSL#3 VSL#3 NNP cord-015369-72cjogxz 705 8 on on IN cord-015369-72cjogxz 705 9 the the DT cord-015369-72cjogxz 705 10 epithelial epithelial JJ cord-015369-72cjogxz 705 11 barrier barrier NN cord-015369-72cjogxz 705 12 was be VBD cord-015369-72cjogxz 705 13 studied study VBN cord-015369-72cjogxz 705 14 in in IN cord-015369-72cjogxz 705 15 Dextran dextran NN cord-015369-72cjogxz 705 16 - - HYPH cord-015369-72cjogxz 705 17 Sodium Sodium NNP cord-015369-72cjogxz 705 18 - - HYPH cord-015369-72cjogxz 705 19 Sulphate Sulphate NNP cord-015369-72cjogxz 705 20 ( ( -LRB- cord-015369-72cjogxz 705 21 DSS)-induced dss)-induce VBN cord-015369-72cjogxz 705 22 colitis colitis NN cord-015369-72cjogxz 705 23 in in IN cord-015369-72cjogxz 705 24 mice mouse NNS cord-015369-72cjogxz 705 25 . . . cord-015369-72cjogxz 706 1 Methods method NNS cord-015369-72cjogxz 706 2 . . . cord-015369-72cjogxz 707 1 Acute acute JJ cord-015369-72cjogxz 707 2 colitis colitis NN cord-015369-72cjogxz 707 3 was be VBD cord-015369-72cjogxz 707 4 induced induce VBN cord-015369-72cjogxz 707 5 in in IN cord-015369-72cjogxz 707 6 balb balb NN cord-015369-72cjogxz 707 7 / / SYM cord-015369-72cjogxz 707 8 c c NN cord-015369-72cjogxz 707 9 mice mouse NNS cord-015369-72cjogxz 707 10 ( ( -LRB- cord-015369-72cjogxz 707 11 3.5 3.5 CD cord-015369-72cjogxz 707 12 % % NN cord-015369-72cjogxz 707 13 DSS DSS NNP cord-015369-72cjogxz 707 14 for for IN cord-015369-72cjogxz 707 15 7 7 CD cord-015369-72cjogxz 707 16 days day NNS cord-015369-72cjogxz 707 17 ) ) -RRB- cord-015369-72cjogxz 707 18 . . . cord-015369-72cjogxz 708 1 Mice mouse NNS cord-015369-72cjogxz 708 2 were be VBD cord-015369-72cjogxz 708 3 treated treat VBN cord-015369-72cjogxz 708 4 with with IN cord-015369-72cjogxz 708 5 either either DT cord-015369-72cjogxz 708 6 15 15 CD cord-015369-72cjogxz 708 7 mg mg NNP cord-015369-72cjogxz 708 8 VSL#3 vsl#3 CD cord-015369-72cjogxz 708 9 or or CC cord-015369-72cjogxz 708 10 placebo placebo NN cord-015369-72cjogxz 708 11 via via IN cord-015369-72cjogxz 708 12 gastric gastric JJ cord-015369-72cjogxz 708 13 tube tube NN cord-015369-72cjogxz 708 14 once once RB cord-015369-72cjogxz 708 15 daily daily RB cord-015369-72cjogxz 708 16 during during IN cord-015369-72cjogxz 708 17 induction induction NN cord-015369-72cjogxz 708 18 of of IN cord-015369-72cjogxz 708 19 colitis colitis NN cord-015369-72cjogxz 708 20 . . . cord-015369-72cjogxz 709 1 Inflammation inflammation NN cord-015369-72cjogxz 709 2 was be VBD cord-015369-72cjogxz 709 3 assessed assess VBN cord-015369-72cjogxz 709 4 by by IN cord-015369-72cjogxz 709 5 clinical clinical JJ cord-015369-72cjogxz 709 6 and and CC cord-015369-72cjogxz 709 7 histological histological JJ cord-015369-72cjogxz 709 8 scores score NNS cord-015369-72cjogxz 709 9 . . . cord-015369-72cjogxz 710 1 Colonic colonic JJ cord-015369-72cjogxz 710 2 permeability permeability NN cord-015369-72cjogxz 710 3 to to IN cord-015369-72cjogxz 710 4 Evans Evans NNP cord-015369-72cjogxz 710 5 blue blue NN cord-015369-72cjogxz 710 6 was be VBD cord-015369-72cjogxz 710 7 measured measure VBN cord-015369-72cjogxz 710 8 in in IN cord-015369-72cjogxz 710 9 vivo vivo NNP cord-015369-72cjogxz 710 10 . . . cord-015369-72cjogxz 711 1 Tight tight JJ cord-015369-72cjogxz 711 2 junction junction NN cord-015369-72cjogxz 711 3 protein protein NN cord-015369-72cjogxz 711 4 expression expression NN cord-015369-72cjogxz 711 5 and and CC cord-015369-72cjogxz 711 6 epithelial epithelial JJ cord-015369-72cjogxz 711 7 apoptotic apoptotic JJ cord-015369-72cjogxz 711 8 ratio ratio NN cord-015369-72cjogxz 711 9 were be VBD cord-015369-72cjogxz 711 10 studied study VBN cord-015369-72cjogxz 711 11 by by IN cord-015369-72cjogxz 711 12 immunofluorescence immunofluorescence NN cord-015369-72cjogxz 711 13 and and CC cord-015369-72cjogxz 711 14 Western western JJ cord-015369-72cjogxz 711 15 blot blot NN cord-015369-72cjogxz 711 16 . . . cord-015369-72cjogxz 712 1 Results result NNS cord-015369-72cjogxz 712 2 . . . cord-015369-72cjogxz 713 1 VSL#3 vsl#3 CD cord-015369-72cjogxz 713 2 treatment treatment NN cord-015369-72cjogxz 713 3 reduced reduce VBN cord-015369-72cjogxz 713 4 inflammation inflammation NN cord-015369-72cjogxz 713 5 ( ( -LRB- cord-015369-72cjogxz 713 6 histological histological JJ cord-015369-72cjogxz 713 7 colitis colitis NN cord-015369-72cjogxz 713 8 scores score NNS cord-015369-72cjogxz 713 9 : : : cord-015369-72cjogxz 713 10 healthy healthy JJ cord-015369-72cjogxz 713 11 control control NN cord-015369-72cjogxz 713 12 0.94 0.94 CD cord-015369-72cjogxz 713 13 AE AE NNP cord-015369-72cjogxz 713 14 0.28 0.28 CD cord-015369-72cjogxz 713 15 , , . cord-015369-72cjogxz 714 1 DSS DSS NNP cord-015369-72cjogxz 714 2 þ þ NNP cord-015369-72cjogxz 715 1 placebo placebo NN cord-015369-72cjogxz 715 2 14.64 14.64 CD cord-015369-72cjogxz 715 3 AE AE NNP cord-015369-72cjogxz 715 4 2.55 2.55 CD cord-015369-72cjogxz 715 5 , , , cord-015369-72cjogxz 715 6 DSS DSS NNP cord-015369-72cjogxz 715 7 þ þ NNP cord-015369-72cjogxz 715 8 VSL#3 VSL#3 NNP cord-015369-72cjogxz 715 9 8.43 8.43 CD cord-015369-72cjogxz 715 10 AE AE NNP cord-015369-72cjogxz 715 11 1.82 1.82 CD cord-015369-72cjogxz 715 12 ; ; : cord-015369-72cjogxz 715 13 p p NN cord-015369-72cjogxz 715 14 ¼ ¼ CD cord-015369-72cjogxz 715 15 0.011 0.011 CD cord-015369-72cjogxz 715 16 ) ) -RRB- cord-015369-72cjogxz 715 17 . . . cord-015369-72cjogxz 716 1 A a DT cord-015369-72cjogxz 716 2 pronounced pronounced JJ cord-015369-72cjogxz 716 3 increase increase NN cord-015369-72cjogxz 716 4 in in IN cord-015369-72cjogxz 716 5 epithelial epithelial JJ cord-015369-72cjogxz 716 6 permeability permeability NN cord-015369-72cjogxz 716 7 in in IN cord-015369-72cjogxz 716 8 acute acute JJ cord-015369-72cjogxz 716 9 colitis colitis NN cord-015369-72cjogxz 716 10 was be VBD cord-015369-72cjogxz 716 11 completely completely RB cord-015369-72cjogxz 716 12 prevented prevent VBN cord-015369-72cjogxz 716 13 by by IN cord-015369-72cjogxz 716 14 VSL#3 VSL#3 NNP cord-015369-72cjogxz 716 15 therapy therapy NN cord-015369-72cjogxz 716 16 ( ( -LRB- cord-015369-72cjogxz 716 17 healthy healthy JJ cord-015369-72cjogxz 716 18 control control NN cord-015369-72cjogxz 716 19 0.4 0.4 CD cord-015369-72cjogxz 716 20 AE AE NNP cord-015369-72cjogxz 716 21 0.07 0.07 CD cord-015369-72cjogxz 716 22 ( ( -LRB- cord-015369-72cjogxz 716 23 Ext./g Ext./g NNP cord-015369-72cjogxz 716 24 ) ) -RRB- cord-015369-72cjogxz 716 25 , , . cord-015369-72cjogxz 717 1 DSS DSS NNP cord-015369-72cjogxz 717 2 þ þ NNP cord-015369-72cjogxz 718 1 placebo placebo NN cord-015369-72cjogxz 718 2 5.75 5.75 CD cord-015369-72cjogxz 718 3 AE AE NNP cord-015369-72cjogxz 718 4 1.67 1.67 CD cord-015369-72cjogxz 718 5 , , , cord-015369-72cjogxz 718 6 DSS DSS NNP cord-015369-72cjogxz 718 7 þ þ NNP cord-015369-72cjogxz 718 8 3 3 CD cord-015369-72cjogxz 718 9 0.26 0.26 CD cord-015369-72cjogxz 718 10 AE AE NNP cord-015369-72cjogxz 718 11 0.08 0.08 CD cord-015369-72cjogxz 718 12 ; ; : cord-015369-72cjogxz 719 1 p p NN cord-015369-72cjogxz 719 2 ¼ ¼ CD cord-015369-72cjogxz 719 3 0.003 0.003 CD cord-015369-72cjogxz 719 4 ) ) -RRB- cord-015369-72cjogxz 719 5 . . . cord-015369-72cjogxz 720 1 In in IN cord-015369-72cjogxz 720 2 acute acute JJ cord-015369-72cjogxz 720 3 colitis colitis NN cord-015369-72cjogxz 720 4 , , , cord-015369-72cjogxz 720 5 decreased decrease VBD cord-015369-72cjogxz 720 6 expression expression NN cord-015369-72cjogxz 720 7 and and CC cord-015369-72cjogxz 720 8 redistribution redistribution NN cord-015369-72cjogxz 720 9 of of IN cord-015369-72cjogxz 720 10 the the DT cord-015369-72cjogxz 720 11 tight tight JJ cord-015369-72cjogxz 720 12 junction junction NN cord-015369-72cjogxz 720 13 proteins protein NNS cord-015369-72cjogxz 720 14 occludin occludin NNP cord-015369-72cjogxz 720 15 , , , cord-015369-72cjogxz 720 16 ZO-1 ZO-1 NNP cord-015369-72cjogxz 720 17 , , , cord-015369-72cjogxz 720 18 claudin-1 claudin-1 NNP cord-015369-72cjogxz 720 19 , , , cord-015369-72cjogxz 720 20 -3 -3 NNP cord-015369-72cjogxz 720 21 , , , cord-015369-72cjogxz 720 22 -4 -4 NNP cord-015369-72cjogxz 720 23 , , , cord-015369-72cjogxz 720 24 and and CC cord-015369-72cjogxz 720 25 -5 -5 NNP cord-015369-72cjogxz 720 26 were be VBD cord-015369-72cjogxz 720 27 observed observe VBN cord-015369-72cjogxz 720 28 , , , cord-015369-72cjogxz 720 29 whereas whereas IN cord-015369-72cjogxz 720 30 VSL#3 vsl#3 CD cord-015369-72cjogxz 720 31 therapy therapy NN cord-015369-72cjogxz 720 32 prevented prevent VBD cord-015369-72cjogxz 720 33 these these DT cord-015369-72cjogxz 720 34 changes change NNS cord-015369-72cjogxz 720 35 . . . cord-015369-72cjogxz 721 1 VSL#3 VSL#3 NNP cord-015369-72cjogxz 721 2 completely completely RB cord-015369-72cjogxz 721 3 prevented prevent VBD cord-015369-72cjogxz 721 4 the the DT cord-015369-72cjogxz 721 5 increase increase NN cord-015369-72cjogxz 721 6 of of IN cord-015369-72cjogxz 721 7 epithelial epithelial JJ cord-015369-72cjogxz 721 8 apoptotic apoptotic JJ cord-015369-72cjogxz 721 9 ratio ratio NN cord-015369-72cjogxz 721 10 in in IN cord-015369-72cjogxz 721 11 acute acute JJ cord-015369-72cjogxz 721 12 colitis colitis NN cord-015369-72cjogxz 721 13 ( ( -LRB- cord-015369-72cjogxz 721 14 healthy healthy JJ cord-015369-72cjogxz 721 15 control control NN cord-015369-72cjogxz 721 16 1.58 1.58 CD cord-015369-72cjogxz 721 17 AE AE NNP cord-015369-72cjogxz 721 18 0.01 0.01 CD cord-015369-72cjogxz 721 19 ( ( -LRB- cord-015369-72cjogxz 721 20 apoptotic apoptotic JJ cord-015369-72cjogxz 721 21 cells/ cells/ CD cord-015369-72cjogxz 721 22 1000 1000 CD cord-015369-72cjogxz 721 23 epithelial epithelial JJ cord-015369-72cjogxz 721 24 cells cell NNS cord-015369-72cjogxz 721 25 ) ) -RRB- cord-015369-72cjogxz 721 26 , , . cord-015369-72cjogxz 722 1 DSS DSS NNP cord-015369-72cjogxz 722 2 þ þ NNP cord-015369-72cjogxz 723 1 placebo placebo NN cord-015369-72cjogxz 723 2 13.33 13.33 CD cord-015369-72cjogxz 723 3 AE AE NNP cord-015369-72cjogxz 723 4 1.29 1.29 CD cord-015369-72cjogxz 723 5 , , , cord-015369-72cjogxz 724 1 DSS DSS NNP cord-015369-72cjogxz 724 2 þ þ NNP cord-015369-72cjogxz 724 3 VSL#3 VSL#3 NNP cord-015369-72cjogxz 724 4 1.72 1.72 CD cord-015369-72cjogxz 724 5 AE AE NNP cord-015369-72cjogxz 724 6 0.1 0.1 CD cord-015369-72cjogxz 724 7 ; ; : cord-015369-72cjogxz 724 8 p p NN cord-015369-72cjogxz 724 9 ¼ ¼ CD cord-015369-72cjogxz 724 10 0.012 0.012 CD cord-015369-72cjogxz 724 11 ) ) -RRB- cord-015369-72cjogxz 724 12 . . . cord-015369-72cjogxz 725 1 Conclusions conclusion NNS cord-015369-72cjogxz 725 2 . . . cord-015369-72cjogxz 726 1 Probiotic probiotic JJ cord-015369-72cjogxz 726 2 therapy therapy NN cord-015369-72cjogxz 726 3 protects protect VBZ cord-015369-72cjogxz 726 4 the the DT cord-015369-72cjogxz 726 5 epithelial epithelial JJ cord-015369-72cjogxz 726 6 barrier barrier NN cord-015369-72cjogxz 726 7 in in IN cord-015369-72cjogxz 726 8 acute acute JJ cord-015369-72cjogxz 726 9 colitis colitis NN cord-015369-72cjogxz 726 10 by by IN cord-015369-72cjogxz 726 11 preventing prevent VBG cord-015369-72cjogxz 726 12 ( ( -LRB- cord-015369-72cjogxz 726 13 1 1 CD cord-015369-72cjogxz 726 14 ) ) -RRB- cord-015369-72cjogxz 726 15 decreased decrease VBD cord-015369-72cjogxz 726 16 tight tight JJ cord-015369-72cjogxz 726 17 junction junction NN cord-015369-72cjogxz 726 18 protein protein NN cord-015369-72cjogxz 726 19 expression expression NN cord-015369-72cjogxz 726 20 , , , cord-015369-72cjogxz 726 21 ( ( -LRB- cord-015369-72cjogxz 726 22 2 2 LS cord-015369-72cjogxz 726 23 ) ) -RRB- cord-015369-72cjogxz 726 24 increased increase VBN cord-015369-72cjogxz 726 25 apoptotic apoptotic JJ cord-015369-72cjogxz 726 26 ratio ratio NN cord-015369-72cjogxz 726 27 . . . cord-015369-72cjogxz 727 1 Background background NN cord-015369-72cjogxz 727 2 . . . cord-015369-72cjogxz 728 1 To to TO cord-015369-72cjogxz 728 2 prospectively prospectively RB cord-015369-72cjogxz 728 3 compare compare VB cord-015369-72cjogxz 728 4 the the DT cord-015369-72cjogxz 728 5 accuracy accuracy NN cord-015369-72cjogxz 728 6 of of IN cord-015369-72cjogxz 728 7 liver liver NN cord-015369-72cjogxz 728 8 fat fat NN cord-015369-72cjogxz 728 9 quantification quantification NN cord-015369-72cjogxz 728 10 using use VBG cord-015369-72cjogxz 728 11 chemical chemical JJ cord-015369-72cjogxz 728 12 shift shift NN cord-015369-72cjogxz 728 13 imaging imaging NN cord-015369-72cjogxz 728 14 and and CC cord-015369-72cjogxz 728 15 H1 H1 NNP cord-015369-72cjogxz 728 16 MR MR NNP cord-015369-72cjogxz 728 17 - - HYPH cord-015369-72cjogxz 728 18 spectroscopy spectroscopy NNP cord-015369-72cjogxz 728 19 at at IN cord-015369-72cjogxz 728 20 3.0 3.0 CD cord-015369-72cjogxz 728 21 Tesla Tesla NNP cord-015369-72cjogxz 728 22 field field NN cord-015369-72cjogxz 728 23 strength strength NN cord-015369-72cjogxz 728 24 in in IN cord-015369-72cjogxz 728 25 patients patient NNS cord-015369-72cjogxz 728 26 undergoing undergo VBG cord-015369-72cjogxz 728 27 major major JJ cord-015369-72cjogxz 728 28 hepatic hepatic JJ cord-015369-72cjogxz 728 29 surgery surgery NN cord-015369-72cjogxz 728 30 . . . cord-015369-72cjogxz 729 1 Methods method NNS cord-015369-72cjogxz 729 2 . . . cord-015369-72cjogxz 730 1 The the DT cord-015369-72cjogxz 730 2 study study NN cord-015369-72cjogxz 730 3 was be VBD cord-015369-72cjogxz 730 4 approved approve VBN cord-015369-72cjogxz 730 5 by by IN cord-015369-72cjogxz 730 6 our -PRON- PRP$ cord-015369-72cjogxz 730 7 local local JJ cord-015369-72cjogxz 730 8 IRB IRB NNP cord-015369-72cjogxz 730 9 and and CC cord-015369-72cjogxz 730 10 a a DT cord-015369-72cjogxz 730 11 total total NN cord-015369-72cjogxz 730 12 of of IN cord-015369-72cjogxz 730 13 13 13 CD cord-015369-72cjogxz 730 14 patients patient NNS cord-015369-72cjogxz 730 15 , , , cord-015369-72cjogxz 730 16 planned plan VBN cord-015369-72cjogxz 730 17 for for IN cord-015369-72cjogxz 730 18 metasectomy metasectomy NNP cord-015369-72cjogxz 730 19 , , , cord-015369-72cjogxz 730 20 were be VBD cord-015369-72cjogxz 730 21 prospectively prospectively RB cord-015369-72cjogxz 730 22 included include VBN cord-015369-72cjogxz 730 23 after after IN cord-015369-72cjogxz 730 24 signing sign VBG cord-015369-72cjogxz 730 25 informed informed JJ cord-015369-72cjogxz 730 26 consent consent NN cord-015369-72cjogxz 730 27 . . . cord-015369-72cjogxz 731 1 Preoperative Preoperative NNP cord-015369-72cjogxz 731 2 3.0 3.0 CD cord-015369-72cjogxz 731 3 Tesla Tesla NNP cord-015369-72cjogxz 731 4 MRI MRI NNP cord-015369-72cjogxz 731 5 ( ( -LRB- cord-015369-72cjogxz 731 6 Trio Trio NNP cord-015369-72cjogxz 731 7 , , , cord-015369-72cjogxz 731 8 Siemens Siemens NNP cord-015369-72cjogxz 731 9 ) ) -RRB- cord-015369-72cjogxz 731 10 of of IN cord-015369-72cjogxz 731 11 the the DT cord-015369-72cjogxz 731 12 liver liver NN cord-015369-72cjogxz 731 13 included include VBD cord-015369-72cjogxz 731 14 T1w T1w NNP cord-015369-72cjogxz 731 15 2D 2d NN cord-015369-72cjogxz 731 16 GRE GRE NNP cord-015369-72cjogxz 732 1 single single JJ cord-015369-72cjogxz 732 2 breath breath NN cord-015369-72cjogxz 732 3 hold hold NN cord-015369-72cjogxz 732 4 in in IN cord-015369-72cjogxz 732 5 - - HYPH cord-015369-72cjogxz 732 6 and and CC cord-015369-72cjogxz 732 7 opposed oppose VBN cord-015369-72cjogxz 732 8 phase phase NN cord-015369-72cjogxz 732 9 sequences sequence NNS cord-015369-72cjogxz 732 10 ( ( -LRB- cord-015369-72cjogxz 732 11 TE TE NNP cord-015369-72cjogxz 732 12 2.46/ 2.46/ CD cord-015369-72cjogxz 732 13 3.69 3.69 CD cord-015369-72cjogxz 732 14 ms ms NNP cord-015369-72cjogxz 732 15 ) ) -RRB- cord-015369-72cjogxz 732 16 and and CC cord-015369-72cjogxz 732 17 a a DT cord-015369-72cjogxz 732 18 single single JJ cord-015369-72cjogxz 732 19 breath breath NN cord-015369-72cjogxz 732 20 hold hold VB cord-015369-72cjogxz 732 21 single single JJ cord-015369-72cjogxz 732 22 voxel voxel NN cord-015369-72cjogxz 732 23 H1 H1 NNP cord-015369-72cjogxz 732 24 MR MR NNP cord-015369-72cjogxz 732 25 - - HYPH cord-015369-72cjogxz 732 26 spectroscopy spectroscopy NNP cord-015369-72cjogxz 732 27 ( ( -LRB- cord-015369-72cjogxz 732 28 VOI VOI NNP cord-015369-72cjogxz 732 29 9 9 CD cord-015369-72cjogxz 732 30 cm cm NN cord-015369-72cjogxz 732 31 3 3 CD cord-015369-72cjogxz 732 32 ; ; : cord-015369-72cjogxz 732 33 TE TE NNP cord-015369-72cjogxz 732 34 30 30 CD cord-015369-72cjogxz 732 35 ms ms NNP cord-015369-72cjogxz 732 36 ) ) -RRB- cord-015369-72cjogxz 732 37 . . . cord-015369-72cjogxz 733 1 With with IN cord-015369-72cjogxz 733 2 chemical chemical JJ cord-015369-72cjogxz 733 3 shift shift NN cord-015369-72cjogxz 733 4 imaging image VBG cord-015369-72cjogxz 733 5 liver liver NN cord-015369-72cjogxz 733 6 fat fat NN cord-015369-72cjogxz 733 7 was be VBD cord-015369-72cjogxz 733 8 quantified quantify VBN cord-015369-72cjogxz 733 9 with with IN cord-015369-72cjogxz 733 10 the the DT cord-015369-72cjogxz 733 11 relative relative JJ cord-015369-72cjogxz 733 12 loss loss NN cord-015369-72cjogxz 733 13 of of IN cord-015369-72cjogxz 733 14 the the DT cord-015369-72cjogxz 733 15 liver liver NN cord-015369-72cjogxz 733 16 - - HYPH cord-015369-72cjogxz 733 17 to to IN cord-015369-72cjogxz 733 18 - - HYPH cord-015369-72cjogxz 733 19 spleen spleen NN cord-015369-72cjogxz 733 20 signal signal NN cord-015369-72cjogxz 733 21 intensity intensity NN cord-015369-72cjogxz 733 22 ratio ratio NN cord-015369-72cjogxz 733 23 on on IN cord-015369-72cjogxz 733 24 the the DT cord-015369-72cjogxz 733 25 opposed oppose VBN cord-015369-72cjogxz 733 26 - - HYPH cord-015369-72cjogxz 733 27 phase phase NN cord-015369-72cjogxz 733 28 images image NNS cord-015369-72cjogxz 733 29 compared compare VBN cord-015369-72cjogxz 733 30 to to IN cord-015369-72cjogxz 733 31 the the DT cord-015369-72cjogxz 733 32 inphase inphase NN cord-015369-72cjogxz 733 33 images image NNS cord-015369-72cjogxz 733 34 . . . cord-015369-72cjogxz 734 1 With with IN cord-015369-72cjogxz 734 2 H1-spectroscopy h1-spectroscopy RB cord-015369-72cjogxz 734 3 liver liver NN cord-015369-72cjogxz 734 4 steatosis steatosis NN cord-015369-72cjogxz 734 5 was be VBD cord-015369-72cjogxz 734 6 quantified quantify VBN cord-015369-72cjogxz 734 7 by by IN cord-015369-72cjogxz 734 8 calculating calculate VBG cord-015369-72cjogxz 734 9 the the DT cord-015369-72cjogxz 734 10 integral integral NN cord-015369-72cjogxz 734 11 of of IN cord-015369-72cjogxz 734 12 the the DT cord-015369-72cjogxz 734 13 water water NN cord-015369-72cjogxz 734 14 and and CC cord-015369-72cjogxz 734 15 fat fat JJ cord-015369-72cjogxz 734 16 spectra spectrum NNS cord-015369-72cjogxz 734 17 . . . cord-015369-72cjogxz 735 1 The the DT cord-015369-72cjogxz 735 2 standard standard NN cord-015369-72cjogxz 735 3 of of IN cord-015369-72cjogxz 735 4 truth truth NN cord-015369-72cjogxz 735 5 was be VBD cord-015369-72cjogxz 735 6 defined define VBN cord-015369-72cjogxz 735 7 by by IN cord-015369-72cjogxz 735 8 histopathological histopathological NNP cord-015369-72cjogxz 735 9 analysis analysis NN cord-015369-72cjogxz 735 10 of of IN cord-015369-72cjogxz 735 11 the the DT cord-015369-72cjogxz 735 12 surgical surgical JJ cord-015369-72cjogxz 735 13 specimens specimen NNS cord-015369-72cjogxz 735 14 according accord VBG cord-015369-72cjogxz 735 15 to to IN cord-015369-72cjogxz 735 16 a a DT cord-015369-72cjogxz 735 17 five five CD cord-015369-72cjogxz 735 18 - - HYPH cord-015369-72cjogxz 735 19 point point NN cord-015369-72cjogxz 735 20 scale scale NN cord-015369-72cjogxz 735 21 ( ( -LRB- cord-015369-72cjogxz 735 22 1 1 CD cord-015369-72cjogxz 735 23 -no -no CD cord-015369-72cjogxz 735 24 steatosis steatosis NN cord-015369-72cjogxz 735 25 ; ; : cord-015369-72cjogxz 735 26 5 5 CD cord-015369-72cjogxz 735 27 -severe -severe VBG cord-015369-72cjogxz 735 28 steatosis steatosis NN cord-015369-72cjogxz 735 29 ) ) -RRB- cord-015369-72cjogxz 735 30 . . . cord-015369-72cjogxz 736 1 Spearman Spearman NNP cord-015369-72cjogxz 736 2 's 's POS cord-015369-72cjogxz 736 3 rank rank NN cord-015369-72cjogxz 736 4 correlation correlation NN cord-015369-72cjogxz 736 5 was be VBD cord-015369-72cjogxz 736 6 used use VBN cord-015369-72cjogxz 736 7 for for IN cord-015369-72cjogxz 736 8 statistical statistical JJ cord-015369-72cjogxz 736 9 analysis analysis NN cord-015369-72cjogxz 736 10 . . . cord-015369-72cjogxz 737 1 Results result NNS cord-015369-72cjogxz 737 2 . . . cord-015369-72cjogxz 738 1 Both both DT cord-015369-72cjogxz 738 2 H1-spectroscopy H1-spectroscopy NNS cord-015369-72cjogxz 738 3 and and CC cord-015369-72cjogxz 738 4 chemical chemical JJ cord-015369-72cjogxz 738 5 - - HYPH cord-015369-72cjogxz 738 6 shift shift NN cord-015369-72cjogxz 738 7 imaging imaging NN cord-015369-72cjogxz 738 8 showed show VBD cord-015369-72cjogxz 738 9 a a DT cord-015369-72cjogxz 738 10 high high JJ cord-015369-72cjogxz 738 11 correlation correlation NN cord-015369-72cjogxz 738 12 of of IN cord-015369-72cjogxz 738 13 the the DT cord-015369-72cjogxz 738 14 liver liver NN cord-015369-72cjogxz 738 15 steatosis steatosis NN cord-015369-72cjogxz 738 16 grading grading NN cord-015369-72cjogxz 738 17 compared compare VBN cord-015369-72cjogxz 738 18 to to IN cord-015369-72cjogxz 738 19 the the DT cord-015369-72cjogxz 738 20 histopathological histopathological NNP cord-015369-72cjogxz 738 21 analysis analysis NN cord-015369-72cjogxz 738 22 ( ( -LRB- cord-015369-72cjogxz 738 23 r r NNP cord-015369-72cjogxz 738 24 ¼ ¼ NNP cord-015369-72cjogxz 738 25 0.83 0.83 CD cord-015369-72cjogxz 738 26 and and CC cord-015369-72cjogxz 738 27 0.75 0.75 CD cord-015369-72cjogxz 738 28 ) ) -RRB- cord-015369-72cjogxz 738 29 . . . cord-015369-72cjogxz 739 1 The the DT cord-015369-72cjogxz 739 2 difference difference NN cord-015369-72cjogxz 739 3 between between IN cord-015369-72cjogxz 739 4 both both DT cord-015369-72cjogxz 739 5 techniques technique NNS cord-015369-72cjogxz 739 6 was be VBD cord-015369-72cjogxz 739 7 not not RB cord-015369-72cjogxz 739 8 significant significant JJ cord-015369-72cjogxz 739 9 ( ( -LRB- cord-015369-72cjogxz 739 10 p p NN cord-015369-72cjogxz 739 11 > > XX cord-015369-72cjogxz 739 12 0.05 0.05 CD cord-015369-72cjogxz 739 13 ) ) -RRB- cord-015369-72cjogxz 739 14 . . . cord-015369-72cjogxz 740 1 Conclusions conclusion NNS cord-015369-72cjogxz 740 2 . . . cord-015369-72cjogxz 741 1 Both both RB cord-015369-72cjogxz 741 2 , , , cord-015369-72cjogxz 741 3 H1 H1 NNP cord-015369-72cjogxz 741 4 MR MR NNP cord-015369-72cjogxz 741 5 - - HYPH cord-015369-72cjogxz 741 6 spectroscopy spectroscopy NNP cord-015369-72cjogxz 741 7 and and CC cord-015369-72cjogxz 741 8 chemical chemical NN cord-015369-72cjogxz 741 9 shift shift NN cord-015369-72cjogxz 741 10 imaging imaging NN cord-015369-72cjogxz 741 11 at at IN cord-015369-72cjogxz 741 12 3.0 3.0 CD cord-015369-72cjogxz 741 13 Tesla Tesla NNP cord-015369-72cjogxz 741 14 , , , cord-015369-72cjogxz 741 15 allow allow VB cord-015369-72cjogxz 741 16 for for IN cord-015369-72cjogxz 741 17 a a DT cord-015369-72cjogxz 741 18 noninvasive noninvasive JJ cord-015369-72cjogxz 741 19 preoperative preoperative JJ cord-015369-72cjogxz 741 20 assessment assessment NN cord-015369-72cjogxz 741 21 of of IN cord-015369-72cjogxz 741 22 liver liver NN cord-015369-72cjogxz 741 23 steatosis steatosis NN cord-015369-72cjogxz 741 24 with with IN cord-015369-72cjogxz 741 25 high high JJ cord-015369-72cjogxz 741 26 correlation correlation NN cord-015369-72cjogxz 741 27 to to IN cord-015369-72cjogxz 741 28 histopathology histopathology NN cord-015369-72cjogxz 741 29 . . . cord-015369-72cjogxz 742 1 The the DT cord-015369-72cjogxz 742 2 addition addition NN cord-015369-72cjogxz 742 3 of of IN cord-015369-72cjogxz 742 4 bevacizumab bevacizumab NNS cord-015369-72cjogxz 742 5 to to IN cord-015369-72cjogxz 742 6 XELOX XELOX NNP cord-015369-72cjogxz 742 7 / / SYM cord-015369-72cjogxz 742 8 FOLFOX FOLFOX NNP cord-015369-72cjogxz 742 9 is be VBZ cord-015369-72cjogxz 742 10 concidered concidere VBN cord-015369-72cjogxz 742 11 as as IN cord-015369-72cjogxz 742 12 standard standard JJ cord-015369-72cjogxz 742 13 in in IN cord-015369-72cjogxz 742 14 the the DT cord-015369-72cjogxz 742 15 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 742 16 treatment treatment NN cord-015369-72cjogxz 742 17 of of IN cord-015369-72cjogxz 742 18 colorectal colorectal JJ cord-015369-72cjogxz 742 19 cancer cancer NN cord-015369-72cjogxz 742 20 liver liver NN cord-015369-72cjogxz 742 21 metastases metastasis NNS cord-015369-72cjogxz 742 22 . . . cord-015369-72cjogxz 743 1 Since since IN cord-015369-72cjogxz 743 2 bevacizumab bevacizumab NNP cord-015369-72cjogxz 743 3 does do VBZ cord-015369-72cjogxz 743 4 not not RB cord-015369-72cjogxz 743 5 exert exert VB cord-015369-72cjogxz 743 6 direct direct JJ cord-015369-72cjogxz 743 7 cytotoxicity cytotoxicity NN cord-015369-72cjogxz 743 8 , , , cord-015369-72cjogxz 743 9 the the DT cord-015369-72cjogxz 743 10 concept concept NN cord-015369-72cjogxz 743 11 of of IN cord-015369-72cjogxz 743 12 tumor tumor NN cord-015369-72cjogxz 743 13 response response NN cord-015369-72cjogxz 743 14 as as IN cord-015369-72cjogxz 743 15 indicator indicator NN cord-015369-72cjogxz 743 16 of of IN cord-015369-72cjogxz 743 17 efficacy efficacy NN cord-015369-72cjogxz 743 18 upon upon IN cord-015369-72cjogxz 743 19 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 743 20 therapy therapy NN cord-015369-72cjogxz 743 21 containing contain VBG cord-015369-72cjogxz 743 22 bevacizumab bevacizumab NNP cord-015369-72cjogxz 743 23 is be VBZ cord-015369-72cjogxz 743 24 being be VBG cord-015369-72cjogxz 743 25 challanged challange VBN cord-015369-72cjogxz 743 26 . . . cord-015369-72cjogxz 744 1 Cytotoxic cytotoxic JJ cord-015369-72cjogxz 744 2 therapy therapy NN cord-015369-72cjogxz 744 3 of of IN cord-015369-72cjogxz 744 4 liver liver NN cord-015369-72cjogxz 744 5 metastases metastasis NNS cord-015369-72cjogxz 744 6 results result NNS cord-015369-72cjogxz 744 7 in in IN cord-015369-72cjogxz 744 8 pathologic pathologic JJ cord-015369-72cjogxz 744 9 response response NN cord-015369-72cjogxz 744 10 of of IN cord-015369-72cjogxz 744 11 various various JJ cord-015369-72cjogxz 744 12 grades grade NNS cord-015369-72cjogxz 744 13 , , , cord-015369-72cjogxz 744 14 however however RB cord-015369-72cjogxz 744 15 the the DT cord-015369-72cjogxz 744 16 effect effect NN cord-015369-72cjogxz 744 17 of of IN cord-015369-72cjogxz 744 18 bevacizumab bevacizumab NNP cord-015369-72cjogxz 744 19 on on IN cord-015369-72cjogxz 744 20 pathologic pathologic JJ cord-015369-72cjogxz 744 21 response response NN cord-015369-72cjogxz 744 22 is be VBZ cord-015369-72cjogxz 744 23 unclear unclear JJ cord-015369-72cjogxz 744 24 . . . cord-015369-72cjogxz 745 1 We -PRON- PRP cord-015369-72cjogxz 745 2 retrospectively retrospectively RB cord-015369-72cjogxz 745 3 analyzed analyze VBD cord-015369-72cjogxz 745 4 specimen specimen NN cord-015369-72cjogxz 745 5 of of IN cord-015369-72cjogxz 745 6 liver liver NN cord-015369-72cjogxz 745 7 metastases metastasis NNS cord-015369-72cjogxz 745 8 of of IN cord-015369-72cjogxz 745 9 patients patient NNS cord-015369-72cjogxz 745 10 treated treat VBN cord-015369-72cjogxz 745 11 with with IN cord-015369-72cjogxz 745 12 XELOX XELOX NNP cord-015369-72cjogxz 745 13 / / SYM cord-015369-72cjogxz 745 14 FOLFOX FOLFOX NNP cord-015369-72cjogxz 745 15 or or CC cord-015369-72cjogxz 745 16 XELOX XELOX NNP cord-015369-72cjogxz 745 17 plus plus CC cord-015369-72cjogxz 745 18 bevacizumab bevacizumab NNP cord-015369-72cjogxz 745 19 . . . cord-015369-72cjogxz 746 1 We -PRON- PRP cord-015369-72cjogxz 746 2 report report VBP cord-015369-72cjogxz 746 3 that that IN cord-015369-72cjogxz 746 4 bevacizumab bevacizumab NNP cord-015369-72cjogxz 746 5 , , , cord-015369-72cjogxz 746 6 when when WRB cord-015369-72cjogxz 746 7 combined combine VBN cord-015369-72cjogxz 746 8 with with IN cord-015369-72cjogxz 746 9 XELOX XELOX NNP cord-015369-72cjogxz 746 10 / / SYM cord-015369-72cjogxz 746 11 FOLFOX FOLFOX NNP cord-015369-72cjogxz 746 12 , , , cord-015369-72cjogxz 746 13 increases increase VBZ cord-015369-72cjogxz 746 14 the the DT cord-015369-72cjogxz 746 15 extent extent NN cord-015369-72cjogxz 746 16 of of IN cord-015369-72cjogxz 746 17 necrosis necrosis NN cord-015369-72cjogxz 746 18 and and CC cord-015369-72cjogxz 746 19 decreases decrease VBZ cord-015369-72cjogxz 746 20 the the DT cord-015369-72cjogxz 746 21 amount amount NN cord-015369-72cjogxz 746 22 of of IN cord-015369-72cjogxz 746 23 fibrosis fibrosis NN cord-015369-72cjogxz 746 24 in in IN cord-015369-72cjogxz 746 25 colorectal colorectal JJ cord-015369-72cjogxz 746 26 liver liver NN cord-015369-72cjogxz 746 27 metastases metastasis NNS cord-015369-72cjogxz 746 28 compared compare VBN cord-015369-72cjogxz 746 29 to to IN cord-015369-72cjogxz 746 30 XELOX XELOX NNP cord-015369-72cjogxz 746 31 / / SYM cord-015369-72cjogxz 746 32 FOLFOX FOLFOX NNP cord-015369-72cjogxz 746 33 alone alone RB cord-015369-72cjogxz 746 34 . . . cord-015369-72cjogxz 747 1 However however RB cord-015369-72cjogxz 747 2 , , , cord-015369-72cjogxz 747 3 bevacizumab bevacizumab NNP cord-015369-72cjogxz 747 4 does do VBZ cord-015369-72cjogxz 747 5 not not RB cord-015369-72cjogxz 747 6 change change VB cord-015369-72cjogxz 747 7 the the DT cord-015369-72cjogxz 747 8 radiologic radiologic JJ cord-015369-72cjogxz 747 9 response response NN cord-015369-72cjogxz 747 10 according accord VBG cord-015369-72cjogxz 747 11 to to IN cord-015369-72cjogxz 747 12 RECIST RECIST NNP cord-015369-72cjogxz 747 13 . . . cord-015369-72cjogxz 748 1 We -PRON- PRP cord-015369-72cjogxz 748 2 conclude conclude VBP cord-015369-72cjogxz 748 3 that that IN cord-015369-72cjogxz 748 4 bevacizumab bevacizumab NNP cord-015369-72cjogxz 748 5 improves improve VBZ cord-015369-72cjogxz 748 6 pathologic pathologic JJ cord-015369-72cjogxz 748 7 response response NN cord-015369-72cjogxz 748 8 which which WDT cord-015369-72cjogxz 748 9 has have VBZ cord-015369-72cjogxz 748 10 no no DT cord-015369-72cjogxz 748 11 counterpart counterpart NN cord-015369-72cjogxz 748 12 in in IN cord-015369-72cjogxz 748 13 radiologic radiologic JJ cord-015369-72cjogxz 748 14 response response NN cord-015369-72cjogxz 748 15 . . . cord-015369-72cjogxz 749 1 Role role NN cord-015369-72cjogxz 749 2 of of IN cord-015369-72cjogxz 749 3 hepatic hepatic JJ cord-015369-72cjogxz 749 4 lymph lymph NN cord-015369-72cjogxz 749 5 node node NN cord-015369-72cjogxz 749 6 involvement involvement NN cord-015369-72cjogxz 749 7 within within IN cord-015369-72cjogxz 749 8 the the DT cord-015369-72cjogxz 749 9 hepatic hepatic JJ cord-015369-72cjogxz 749 10 pedicle pedicle NN cord-015369-72cjogxz 749 11 in in IN cord-015369-72cjogxz 749 12 patients patient NNS cord-015369-72cjogxz 749 13 with with IN cord-015369-72cjogxz 749 14 colorectal colorectal JJ cord-015369-72cjogxz 749 15 liver liver NN cord-015369-72cjogxz 749 16 metastases metastasis NNS cord-015369-72cjogxz 749 17 Background Background NNP cord-015369-72cjogxz 749 18 . . . cord-015369-72cjogxz 750 1 Hepatic hepatic JJ cord-015369-72cjogxz 750 2 lymph lymph NN cord-015369-72cjogxz 750 3 node node NN cord-015369-72cjogxz 750 4 involvement involvement NN cord-015369-72cjogxz 750 5 in in IN cord-015369-72cjogxz 750 6 patients patient NNS cord-015369-72cjogxz 750 7 with with IN cord-015369-72cjogxz 750 8 colorectal colorectal JJ cord-015369-72cjogxz 750 9 liver liver NN cord-015369-72cjogxz 750 10 metastases metastasis NNS cord-015369-72cjogxz 750 11 is be VBZ cord-015369-72cjogxz 750 12 an an DT cord-015369-72cjogxz 750 13 important important JJ cord-015369-72cjogxz 750 14 prognostic prognostic JJ cord-015369-72cjogxz 750 15 factor factor NN cord-015369-72cjogxz 750 16 , , , cord-015369-72cjogxz 750 17 but but CC cord-015369-72cjogxz 750 18 the the DT cord-015369-72cjogxz 750 19 role role NN cord-015369-72cjogxz 750 20 of of IN cord-015369-72cjogxz 750 21 lymphadenectomy lymphadenectomy NN cord-015369-72cjogxz 750 22 , , , cord-015369-72cjogxz 750 23 especially especially RB cord-015369-72cjogxz 750 24 of of IN cord-015369-72cjogxz 750 25 the the DT cord-015369-72cjogxz 750 26 hepatic hepatic JJ cord-015369-72cjogxz 750 27 pedicle pedicle NN cord-015369-72cjogxz 750 28 , , , cord-015369-72cjogxz 750 29 is be VBZ cord-015369-72cjogxz 750 30 still still RB cord-015369-72cjogxz 750 31 unknown unknown JJ cord-015369-72cjogxz 750 32 . . . cord-015369-72cjogxz 751 1 Methods method NNS cord-015369-72cjogxz 751 2 . . . cord-015369-72cjogxz 752 1 At at IN cord-015369-72cjogxz 752 2 the the DT cord-015369-72cjogxz 752 3 Medical Medical NNP cord-015369-72cjogxz 752 4 University University NNP cord-015369-72cjogxz 752 5 Graz Graz NNP cord-015369-72cjogxz 752 6 262 262 CD cord-015369-72cjogxz 752 7 patients patient NNS cord-015369-72cjogxz 752 8 , , , cord-015369-72cjogxz 752 9 who who WP cord-015369-72cjogxz 752 10 underwent undergo VBD cord-015369-72cjogxz 752 11 liver liver NN cord-015369-72cjogxz 752 12 resection resection NN cord-015369-72cjogxz 752 13 because because IN cord-015369-72cjogxz 752 14 of of IN cord-015369-72cjogxz 752 15 colorectal colorectal JJ cord-015369-72cjogxz 752 16 liver liver NN cord-015369-72cjogxz 752 17 metastases metastasis NNS cord-015369-72cjogxz 752 18 between between IN cord-015369-72cjogxz 752 19 1991 1991 CD cord-015369-72cjogxz 752 20 and and CC cord-015369-72cjogxz 752 21 2008 2008 CD cord-015369-72cjogxz 752 22 , , , cord-015369-72cjogxz 752 23 were be VBD cord-015369-72cjogxz 752 24 retrospectively retrospectively RB cord-015369-72cjogxz 752 25 reviewed review VBN cord-015369-72cjogxz 752 26 . . . cord-015369-72cjogxz 753 1 Results result NNS cord-015369-72cjogxz 753 2 . . . cord-015369-72cjogxz 754 1 Out out IN cord-015369-72cjogxz 754 2 of of IN cord-015369-72cjogxz 754 3 262 262 CD cord-015369-72cjogxz 754 4 patients patient NNS cord-015369-72cjogxz 754 5 46,6 46,6 CD cord-015369-72cjogxz 754 6 % % NN cord-015369-72cjogxz 754 7 ( ( -LRB- cord-015369-72cjogxz 754 8 122 122 CD cord-015369-72cjogxz 754 9 patients patient NNS cord-015369-72cjogxz 754 10 ) ) -RRB- cord-015369-72cjogxz 754 11 underwent undergo VBD cord-015369-72cjogxz 754 12 combined combine VBN cord-015369-72cjogxz 754 13 hepatectomy hepatectomy NN cord-015369-72cjogxz 754 14 and and CC cord-015369-72cjogxz 754 15 node node NN cord-015369-72cjogxz 754 16 dissection dissection NN cord-015369-72cjogxz 754 17 of of IN cord-015369-72cjogxz 754 18 the the DT cord-015369-72cjogxz 754 19 hepatic hepatic JJ cord-015369-72cjogxz 754 20 pedicle pedicle NN cord-015369-72cjogxz 754 21 , , , cord-015369-72cjogxz 754 22 whereas whereas IN cord-015369-72cjogxz 754 23 140 140 CD cord-015369-72cjogxz 754 24 patients patient NNS cord-015369-72cjogxz 754 25 underwent undergo VBD cord-015369-72cjogxz 754 26 hepatectomy hepatectomy NN cord-015369-72cjogxz 754 27 only only RB cord-015369-72cjogxz 754 28 . . . cord-015369-72cjogxz 755 1 15,6 15,6 CD cord-015369-72cjogxz 755 2 % % NN cord-015369-72cjogxz 755 3 ( ( -LRB- cord-015369-72cjogxz 755 4 19 19 CD cord-015369-72cjogxz 755 5 of of IN cord-015369-72cjogxz 755 6 122 122 CD cord-015369-72cjogxz 755 7 patients patient NNS cord-015369-72cjogxz 755 8 ) ) -RRB- cord-015369-72cjogxz 755 9 were be VBD cord-015369-72cjogxz 755 10 microscopically microscopically RB cord-015369-72cjogxz 755 11 node node NN cord-015369-72cjogxz 755 12 positive positive JJ cord-015369-72cjogxz 755 13 within within IN cord-015369-72cjogxz 755 14 the the DT cord-015369-72cjogxz 755 15 hepatic hepatic JJ cord-015369-72cjogxz 755 16 pedicle pedicle NN cord-015369-72cjogxz 755 17 and and CC cord-015369-72cjogxz 755 18 84,4 84,4 CD cord-015369-72cjogxz 755 19 % % NN cord-015369-72cjogxz 755 20 ( ( -LRB- cord-015369-72cjogxz 755 21 103 103 CD cord-015369-72cjogxz 755 22 of of IN cord-015369-72cjogxz 755 23 122 122 CD cord-015369-72cjogxz 755 24 patients patient NNS cord-015369-72cjogxz 755 25 ) ) -RRB- cord-015369-72cjogxz 755 26 were be VBD cord-015369-72cjogxz 755 27 node node NN cord-015369-72cjogxz 755 28 negative negative JJ cord-015369-72cjogxz 755 29 . . . cord-015369-72cjogxz 756 1 The the DT cord-015369-72cjogxz 756 2 5-year 5-year CD cord-015369-72cjogxz 756 3 survival survival NN cord-015369-72cjogxz 756 4 rate rate NN cord-015369-72cjogxz 756 5 for for IN cord-015369-72cjogxz 756 6 the the DT cord-015369-72cjogxz 756 7 whole whole JJ cord-015369-72cjogxz 756 8 group group NN cord-015369-72cjogxz 756 9 ( ( -LRB- cord-015369-72cjogxz 756 10 262 262 CD cord-015369-72cjogxz 756 11 patients patient NNS cord-015369-72cjogxz 756 12 ) ) -RRB- cord-015369-72cjogxz 756 13 , , , cord-015369-72cjogxz 756 14 for for IN cord-015369-72cjogxz 756 15 the the DT cord-015369-72cjogxz 756 16 node node NN cord-015369-72cjogxz 756 17 positive positive JJ cord-015369-72cjogxz 756 18 group group NN cord-015369-72cjogxz 756 19 ( ( -LRB- cord-015369-72cjogxz 756 20 19 19 CD cord-015369-72cjogxz 756 21 patients patient NNS cord-015369-72cjogxz 756 22 ) ) -RRB- cord-015369-72cjogxz 756 23 and and CC cord-015369-72cjogxz 756 24 the the DT cord-015369-72cjogxz 756 25 node node NN cord-015369-72cjogxz 756 26 negative negative JJ cord-015369-72cjogxz 756 27 group group NN cord-015369-72cjogxz 756 28 ( ( -LRB- cord-015369-72cjogxz 756 29 103 103 CD cord-015369-72cjogxz 756 30 patients patient NNS cord-015369-72cjogxz 756 31 ) ) -RRB- cord-015369-72cjogxz 756 32 was be VBD cord-015369-72cjogxz 756 33 50,4 50,4 CD cord-015369-72cjogxz 756 34 % % NN cord-015369-72cjogxz 756 35 , , , cord-015369-72cjogxz 756 36 18,1 18,1 CD cord-015369-72cjogxz 756 37 % % NN cord-015369-72cjogxz 756 38 and and CC cord-015369-72cjogxz 756 39 65,1 65,1 CD cord-015369-72cjogxz 756 40 % % NN cord-015369-72cjogxz 756 41 with with IN cord-015369-72cjogxz 756 42 a a DT cord-015369-72cjogxz 756 43 median median JJ cord-015369-72cjogxz 756 44 survival survival NN cord-015369-72cjogxz 756 45 time time NN cord-015369-72cjogxz 756 46 of of IN cord-015369-72cjogxz 756 47 1906 1906 CD cord-015369-72cjogxz 756 48 days day NNS cord-015369-72cjogxz 756 49 , , , cord-015369-72cjogxz 756 50 765 765 CD cord-015369-72cjogxz 756 51 days day NNS cord-015369-72cjogxz 756 52 and and CC cord-015369-72cjogxz 756 53 2966 2966 CD cord-015369-72cjogxz 756 54 days day NNS cord-015369-72cjogxz 756 55 respectively respectively RB cord-015369-72cjogxz 756 56 . . . cord-015369-72cjogxz 757 1 The the DT cord-015369-72cjogxz 757 2 difference difference NN cord-015369-72cjogxz 757 3 was be VBD cord-015369-72cjogxz 757 4 significant significant JJ cord-015369-72cjogxz 757 5 ( ( -LRB- cord-015369-72cjogxz 757 6 p p NN cord-015369-72cjogxz 757 7 ¼ ¼ NNP cord-015369-72cjogxz 757 8 0,0017 0,0017 CD cord-015369-72cjogxz 757 9 ) ) -RRB- cord-015369-72cjogxz 757 10 . . . cord-015369-72cjogxz 758 1 Tumor tumor NN cord-015369-72cjogxz 758 2 recurrence recurrence NN cord-015369-72cjogxz 758 3 was be VBD cord-015369-72cjogxz 758 4 found find VBN cord-015369-72cjogxz 758 5 in in IN cord-015369-72cjogxz 758 6 172 172 CD cord-015369-72cjogxz 758 7 patients patient NNS cord-015369-72cjogxz 758 8 ( ( -LRB- cord-015369-72cjogxz 758 9 65,6 65,6 CD cord-015369-72cjogxz 758 10 % % NN cord-015369-72cjogxz 758 11 ) ) -RRB- cord-015369-72cjogxz 758 12 with with IN cord-015369-72cjogxz 758 13 a a DT cord-015369-72cjogxz 758 14 disease disease NN cord-015369-72cjogxz 758 15 free free JJ cord-015369-72cjogxz 758 16 survival survival NN cord-015369-72cjogxz 758 17 ( ( -LRB- cord-015369-72cjogxz 758 18 DFS DFS NNP cord-015369-72cjogxz 758 19 ) ) -RRB- cord-015369-72cjogxz 758 20 of of IN cord-015369-72cjogxz 758 21 620 620 CD cord-015369-72cjogxz 758 22 days day NNS cord-015369-72cjogxz 758 23 in in IN cord-015369-72cjogxz 758 24 the the DT cord-015369-72cjogxz 758 25 whole whole JJ cord-015369-72cjogxz 758 26 group group NN cord-015369-72cjogxz 758 27 , , , cord-015369-72cjogxz 758 28 286 286 CD cord-015369-72cjogxz 758 29 days day NNS cord-015369-72cjogxz 758 30 in in IN cord-015369-72cjogxz 758 31 the the DT cord-015369-72cjogxz 758 32 node node NN cord-015369-72cjogxz 758 33 positive positive JJ cord-015369-72cjogxz 758 34 and and CC cord-015369-72cjogxz 758 35 517 517 CD cord-015369-72cjogxz 758 36 days day NNS cord-015369-72cjogxz 758 37 in in IN cord-015369-72cjogxz 758 38 the the DT cord-015369-72cjogxz 758 39 node node NN cord-015369-72cjogxz 758 40 negative negative JJ cord-015369-72cjogxz 758 41 group group NN cord-015369-72cjogxz 758 42 . . . cord-015369-72cjogxz 759 1 Conclusions conclusion NNS cord-015369-72cjogxz 759 2 . . . cord-015369-72cjogxz 760 1 Patients patient NNS cord-015369-72cjogxz 760 2 with with IN cord-015369-72cjogxz 760 3 positive positive JJ cord-015369-72cjogxz 760 4 lymph lymph NN cord-015369-72cjogxz 760 5 nodes node NNS cord-015369-72cjogxz 760 6 in in IN cord-015369-72cjogxz 760 7 the the DT cord-015369-72cjogxz 760 8 hepatic hepatic JJ cord-015369-72cjogxz 760 9 pedicle pedicle NN cord-015369-72cjogxz 760 10 are be VBP cord-015369-72cjogxz 760 11 at at IN cord-015369-72cjogxz 760 12 high high JJ cord-015369-72cjogxz 760 13 risk risk NN cord-015369-72cjogxz 760 14 for for IN cord-015369-72cjogxz 760 15 a a DT cord-015369-72cjogxz 760 16 shorter short JJR cord-015369-72cjogxz 760 17 DFS DFS NNP cord-015369-72cjogxz 760 18 and and CC cord-015369-72cjogxz 760 19 a a DT cord-015369-72cjogxz 760 20 decreased decrease VBN cord-015369-72cjogxz 760 21 5-year 5-year CD cord-015369-72cjogxz 760 22 survival survival NN cord-015369-72cjogxz 760 23 rate rate NN cord-015369-72cjogxz 760 24 and and CC cord-015369-72cjogxz 760 25 can can MD cord-015369-72cjogxz 760 26 be be VB cord-015369-72cjogxz 760 27 safely safely RB cord-015369-72cjogxz 760 28 identified identify VBN cord-015369-72cjogxz 760 29 by by IN cord-015369-72cjogxz 760 30 lymphadenectomy lymphadenectomy NN cord-015369-72cjogxz 760 31 in in IN cord-015369-72cjogxz 760 32 this this DT cord-015369-72cjogxz 760 33 area area NN cord-015369-72cjogxz 760 34 . . . cord-015369-72cjogxz 761 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 761 2 . . . cord-015369-72cjogxz 762 1 Das Das NNP cord-015369-72cjogxz 762 2 kolorektale kolorektale NNP cord-015369-72cjogxz 762 3 Karzinom Karzinom NNP cord-015369-72cjogxz 762 4 führt führt NNP cord-015369-72cjogxz 762 5 in in IN cord-015369-72cjogxz 762 6 25 25 CD cord-015369-72cjogxz 762 7 % % NN cord-015369-72cjogxz 762 8 der der NN cord-015369-72cjogxz 762 9 Fälle Fälle NNP cord-015369-72cjogxz 762 10 zu zu NNP cord-015369-72cjogxz 762 11 einer einer NNP cord-015369-72cjogxz 762 12 synchronen synchronen JJ cord-015369-72cjogxz 763 1 Leberfiliarsierung Leberfiliarsierung NNP cord-015369-72cjogxz 763 2 -weitere -weitere DT cord-015369-72cjogxz 763 3 25 25 CD cord-015369-72cjogxz 763 4 % % NN cord-015369-72cjogxz 763 5 der der NNP cord-015369-72cjogxz 763 6 Patienten Patienten NNP cord-015369-72cjogxz 763 7 entwickeln entwickeln NNP cord-015369-72cjogxz 763 8 vornehmlich vornehmlich NNP cord-015369-72cjogxz 763 9 in in IN cord-015369-72cjogxz 763 10 den den NNP cord-015369-72cjogxz 763 11 ersten ersten NNP cord-015369-72cjogxz 763 12 beiden beiden JJ cord-015369-72cjogxz 763 13 Jahren Jahren NNP cord-015369-72cjogxz 763 14 nach nach NNP cord-015369-72cjogxz 763 15 Operation Operation NNP cord-015369-72cjogxz 763 16 des des NNP cord-015369-72cjogxz 763 17 Primärtumors Primärtumors NNP cord-015369-72cjogxz 763 18 Metastasen Metastasen NNP cord-015369-72cjogxz 763 19 . . . cord-015369-72cjogxz 764 1 Die die VB cord-015369-72cjogxz 764 2 radikale radikale NN cord-015369-72cjogxz 765 1 Chirurgie Chirurgie NNP cord-015369-72cjogxz 765 2 der der NNP cord-015369-72cjogxz 765 3 Lebermetastasen Lebermetastasen NNP cord-015369-72cjogxz 765 4 stellt stellt NNP cord-015369-72cjogxz 766 1 bis bis NNP cord-015369-72cjogxz 766 2 dato dato NNP cord-015369-72cjogxz 766 3 die die VBP cord-015369-72cjogxz 766 4 einzige einzige NNP cord-015369-72cjogxz 766 5 Chanche Chanche NNP cord-015369-72cjogxz 766 6 auf auf NNP cord-015369-72cjogxz 766 7 Heilung Heilung NNP cord-015369-72cjogxz 766 8 dar dar NNP cord-015369-72cjogxz 766 9 mit mit NNP cord-015369-72cjogxz 766 10 5-Jahres 5-Jahres NNP cord-015369-72cjogxz 766 11 Ü Ü NNP cord-015369-72cjogxz 766 12 berlebensraten berlebensraten NNP cord-015369-72cjogxz 766 13 von von NNP cord-015369-72cjogxz 766 14 30 30 CD cord-015369-72cjogxz 766 15 - - SYM cord-015369-72cjogxz 766 16 50 50 CD cord-015369-72cjogxz 766 17 % % NN cord-015369-72cjogxz 766 18 . . . cord-015369-72cjogxz 767 1 Die die VB cord-015369-72cjogxz 767 2 Rezidivrate Rezidivrate NNP cord-015369-72cjogxz 767 3 nach nach NNP cord-015369-72cjogxz 767 4 Leber Leber NNP cord-015369-72cjogxz 767 5 - - HYPH cord-015369-72cjogxz 767 6 Erstresektionen Erstresektionen NNP cord-015369-72cjogxz 767 7 beträgt beträgt NNP cord-015369-72cjogxz 767 8 60 60 CD cord-015369-72cjogxz 767 9 - - SYM cord-015369-72cjogxz 767 10 70 70 CD cord-015369-72cjogxz 767 11 % % NN cord-015369-72cjogxz 767 12 und und IN cord-015369-72cjogxz 767 13 nur nur RB cord-015369-72cjogxz 767 14 20 20 CD cord-015369-72cjogxz 767 15 % % NN cord-015369-72cjogxz 768 1 dieser dieser NNP cord-015369-72cjogxz 768 2 Patienten Patienten NNP cord-015369-72cjogxz 768 3 sind sind NNP cord-015369-72cjogxz 769 1 einer einer NNP cord-015369-72cjogxz 769 2 weiteren weiteren NNP cord-015369-72cjogxz 769 3 radikalen radikalen NNP cord-015369-72cjogxz 769 4 Leberresektion Leberresektion NNP cord-015369-72cjogxz 769 5 zugänglich zugänglich NNP cord-015369-72cjogxz 769 6 . . . cord-015369-72cjogxz 770 1 Methodik Methodik NNP cord-015369-72cjogxz 770 2 . . . cord-015369-72cjogxz 771 1 Die die VB cord-015369-72cjogxz 771 2 eigenen eigenen NNP cord-015369-72cjogxz 771 3 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 771 4 wurden wurden NNS cord-015369-72cjogxz 772 1 retrospektiv retrospektiv RB cord-015369-72cjogxz 772 2 analysiert analysiert NNP cord-015369-72cjogxz 772 3 und und RB cord-015369-72cjogxz 773 1 mit mit NNP cord-015369-72cjogxz 773 2 den den NNP cord-015369-72cjogxz 773 3 Daten Daten NNP cord-015369-72cjogxz 773 4 der der NNP cord-015369-72cjogxz 773 5 gängigen gängigen NNP cord-015369-72cjogxz 773 6 Literatur Literatur NNP cord-015369-72cjogxz 773 7 verglichen verglichen NN cord-015369-72cjogxz 773 8 . . . cord-015369-72cjogxz 774 1 I -PRON- PRP cord-015369-72cjogxz 775 1 m m NNP cord-015369-72cjogxz 775 2 Zeitraum Zeitraum NNP cord-015369-72cjogxz 775 3 von von NNP cord-015369-72cjogxz 776 1 1/1997 1/1997 CD cord-015369-72cjogxz 777 1 -12/2008 -12/2008 NFP cord-015369-72cjogxz 777 2 erfolgten erfolgten NNP cord-015369-72cjogxz 777 3 an an DT cord-015369-72cjogxz 777 4 40 40 CD cord-015369-72cjogxz 777 5 Patienten Patienten NNP cord-015369-72cjogxz 777 6 insgesamt insgesamt NNP cord-015369-72cjogxz 777 7 n n NN cord-015369-72cjogxz 777 8 ¼ ¼ NNP cord-015369-72cjogxz 777 9 57 57 CD cord-015369-72cjogxz 777 10 Leberteilresektionen Leberteilresektionen NNP cord-015369-72cjogxz 777 11 wegen wegen NNP cord-015369-72cjogxz 777 12 Metastasen Metastasen NNP cord-015369-72cjogxz 777 13 eines eines NNP cord-015369-72cjogxz 777 14 Kolo Kolo NNP cord-015369-72cjogxz 777 15 - - HYPH cord-015369-72cjogxz 777 16 Rektalen Rektalen NNP cord-015369-72cjogxz 777 17 Karzinoms Karzinoms NNP cord-015369-72cjogxz 777 18 ; ; : cord-015369-72cjogxz 778 1 n n NNP cord-015369-72cjogxz 778 2 ¼ ¼ NNP cord-015369-72cjogxz 778 3 29 29 CD cord-015369-72cjogxz 779 1 Patienten Patienten NNP cord-015369-72cjogxz 779 2 wurden wurden VBD cord-015369-72cjogxz 779 3 einmal einmal NNP cord-015369-72cjogxz 779 4 und und NNP cord-015369-72cjogxz 779 5 n n NNP cord-015369-72cjogxz 779 6 ¼ ¼ NNP cord-015369-72cjogxz 779 7 11 11 CD cord-015369-72cjogxz 779 8 Patienten Patienten NNP cord-015369-72cjogxz 779 9 mehrfach mehrfach NNP cord-015369-72cjogxz 779 10 reseziert reseziert NNP cord-015369-72cjogxz 779 11 . . . cord-015369-72cjogxz 780 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 780 2 . . . cord-015369-72cjogxz 781 1 Bei Bei NNP cord-015369-72cjogxz 781 2 den den NNP cord-015369-72cjogxz 782 1 Patienten Patienten NNP cord-015369-72cjogxz 782 2 handelte handelte NNP cord-015369-72cjogxz 783 1 es es NNP cord-015369-72cjogxz 783 2 sich sich NNP cord-015369-72cjogxz 783 3 um um UH cord-015369-72cjogxz 783 4 22 22 CD cord-015369-72cjogxz 783 5 Männer Männer NNPS cord-015369-72cjogxz 783 6 und und IN cord-015369-72cjogxz 783 7 18 18 CD cord-015369-72cjogxz 783 8 Frauen Frauen NNP cord-015369-72cjogxz 783 9 in in IN cord-015369-72cjogxz 783 10 einem einem NNP cord-015369-72cjogxz 783 11 durchschnittlichen durchschnittlichen NNP cord-015369-72cjogxz 783 12 Alter Alter NNP cord-015369-72cjogxz 783 13 von von NNP cord-015369-72cjogxz 783 14 62 62 CD cord-015369-72cjogxz 783 15 Jahren Jahren NNP cord-015369-72cjogxz 783 16 . . . cord-015369-72cjogxz 784 1 Bei Bei NNP cord-015369-72cjogxz 784 2 n n NNP cord-015369-72cjogxz 785 1 ¼ ¼ NNP cord-015369-72cjogxz 785 2 11 11 CD cord-015369-72cjogxz 786 1 Patienten Patienten NNP cord-015369-72cjogxz 786 2 erfolgten erfolgten NNP cord-015369-72cjogxz 786 3 eine eine NNP cord-015369-72cjogxz 786 4 oder oder NNP cord-015369-72cjogxz 786 5 mehrere mehrere NNP cord-015369-72cjogxz 786 6 -bis -bis . cord-015369-72cjogxz 787 1 maximal maximal JJ cord-015369-72cjogxz 787 2 6 6 CD cord-015369-72cjogxz 787 3 Re re NN cord-015369-72cjogxz 787 4 - - NN cord-015369-72cjogxz 787 5 Resektionen Resektionen NNP cord-015369-72cjogxz 787 6 , , , cord-015369-72cjogxz 787 7 wobei wobei NNP cord-015369-72cjogxz 787 8 in in IN cord-015369-72cjogxz 787 9 allen allen NNP cord-015369-72cjogxz 787 10 Fällen Fällen NNP cord-015369-72cjogxz 787 11 eine eine NNP cord-015369-72cjogxz 787 12 R-0 R-0 NNP cord-015369-72cjogxz 787 13 Situation situation NN cord-015369-72cjogxz 787 14 erreicht erreicht NN cord-015369-72cjogxz 787 15 wurde wurde NN cord-015369-72cjogxz 787 16 . . . cord-015369-72cjogxz 788 1 Mortalität Mortalität NNS cord-015369-72cjogxz 788 2 und und IN cord-015369-72cjogxz 788 3 Morbidität Morbidität NNP cord-015369-72cjogxz 788 4 waren waren VBD cord-015369-72cjogxz 788 5 hierbei hierbei NNP cord-015369-72cjogxz 788 6 gering gering NNP cord-015369-72cjogxz 788 7 ( ( -LRB- cord-015369-72cjogxz 788 8 0 0 NFP cord-015369-72cjogxz 788 9 bzw.27 bzw.27 NN cord-015369-72cjogxz 788 10 % % NN cord-015369-72cjogxz 788 11 ) ) -RRB- cord-015369-72cjogxz 789 1 und und NNP cord-015369-72cjogxz 789 2 führten führten NNP cord-015369-72cjogxz 789 3 zu zu NNP cord-015369-72cjogxz 789 4 einem einem NNP cord-015369-72cjogxz 789 5 durchschnittlichen durchschnittlichen NNP cord-015369-72cjogxz 789 6 stationären stationären VBZ cord-015369-72cjogxz 789 7 Aufenthalt Aufenthalt NNP cord-015369-72cjogxz 789 8 von von NNP cord-015369-72cjogxz 789 9 7.5 7.5 CD cord-015369-72cjogxz 789 10 Tagen Tagen NNP cord-015369-72cjogxz 789 11 . . . cord-015369-72cjogxz 790 1 Inzwischen Inzwischen NNP cord-015369-72cjogxz 790 2 sind sind NNP cord-015369-72cjogxz 790 3 n n NNP cord-015369-72cjogxz 790 4 ¼ ¼ NNP cord-015369-72cjogxz 790 5 5 5 CD cord-015369-72cjogxz 790 6 Patienten Patienten NNP cord-015369-72cjogxz 790 7 -bei -bei HYPH cord-015369-72cjogxz 790 8 einem einem NNP cord-015369-72cjogxz 790 9 mittleren mittleren NNP cord-015369-72cjogxz 791 1 Ü Ü NNP cord-015369-72cjogxz 791 2 berleben berleben NNP cord-015369-72cjogxz 792 1 von von NNP cord-015369-72cjogxz 792 2 28 28 CD cord-015369-72cjogxz 792 3 Monaten Monaten NNP cord-015369-72cjogxz 792 4 ( ( -LRB- cord-015369-72cjogxz 792 5 min min NNP cord-015369-72cjogxz 792 6 22 22 CD cord-015369-72cjogxz 792 7 , , , cord-015369-72cjogxz 793 1 max max NNP cord-015369-72cjogxz 793 2 76 76 CD cord-015369-72cjogxz 794 1 Monate Monate NNP cord-015369-72cjogxz 794 2 ) ) -RRB- cord-015369-72cjogxz 794 3 -verstorben -verstorben NFP cord-015369-72cjogxz 794 4 ; ; : cord-015369-72cjogxz 795 1 n n CC cord-015369-72cjogxz 795 2 ¼ ¼ NNP cord-015369-72cjogxz 795 3 6 6 CD cord-015369-72cjogxz 795 4 Patienten Patienten NNP cord-015369-72cjogxz 795 5 , , , cord-015369-72cjogxz 795 6 bei bei NNP cord-015369-72cjogxz 795 7 einem einem NNP cord-015369-72cjogxz 795 8 mittlerem mittlerem NNP cord-015369-72cjogxz 795 9 Ü Ü NNP cord-015369-72cjogxz 795 10 berleben berleben NNP cord-015369-72cjogxz 795 11 von von NNP cord-015369-72cjogxz 795 12 58 58 CD cord-015369-72cjogxz 795 13 Monaten Monaten NNP cord-015369-72cjogxz 795 14 ( ( -LRB- cord-015369-72cjogxz 795 15 min min NNP cord-015369-72cjogxz 795 16 16 16 CD cord-015369-72cjogxz 795 17 , , , cord-015369-72cjogxz 795 18 max max NNP cord-015369-72cjogxz 795 19 84 84 CD cord-015369-72cjogxz 795 20 Monate Monate NNP cord-015369-72cjogxz 795 21 ) ) -RRB- cord-015369-72cjogxz 796 1 sind sind NNPS cord-015369-72cjogxz 796 2 tumorfrei tumorfrei NNP cord-015369-72cjogxz 796 3 am be VBP cord-015369-72cjogxz 796 4 Leben Leben NNP cord-015369-72cjogxz 796 5 . . . cord-015369-72cjogxz 797 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 797 2 . . . cord-015369-72cjogxz 798 1 Auch Auch NNP cord-015369-72cjogxz 798 2 wiederholte wiederholte NNP cord-015369-72cjogxz 798 3 Leberteilresektionen Leberteilresektionen NNP cord-015369-72cjogxz 798 4 bei bei NNP cord-015369-72cjogxz 798 5 Metastasen Metastasen NNP cord-015369-72cjogxz 798 6 eines eine NNS cord-015369-72cjogxz 799 1 Kolo Kolo NNP cord-015369-72cjogxz 799 2 - - HYPH cord-015369-72cjogxz 799 3 Rektalen Rektalen NNP cord-015369-72cjogxz 799 4 Karzinoms Karzinoms NNP cord-015369-72cjogxz 800 1 sind sind NNP cord-015369-72cjogxz 800 2 mit mit NNP cord-015369-72cjogxz 800 3 einer einer NNP cord-015369-72cjogxz 800 4 niederen niederen NNP cord-015369-72cjogxz 800 5 Mortalität Mortalität NNP cord-015369-72cjogxz 800 6 und und IN cord-015369-72cjogxz 800 7 Morbidität Morbidität NNP cord-015369-72cjogxz 800 8 durchführbar durchführbar NN cord-015369-72cjogxz 801 1 ; ; : cord-015369-72cjogxz 801 2 entscheidend entscheidend NNP cord-015369-72cjogxz 801 3 für für NNP cord-015369-72cjogxz 801 4 das das NNP cord-015369-72cjogxz 801 5 Langzeitüberleben Langzeitüberleben NNP cord-015369-72cjogxz 801 6 ist ist NN cord-015369-72cjogxz 801 7 die die VBP cord-015369-72cjogxz 801 8 R-0 r-0 NN cord-015369-72cjogxz 802 1 Resektion Resektion NNP cord-015369-72cjogxz 802 2 . . . cord-015369-72cjogxz 803 1 Background background NN cord-015369-72cjogxz 803 2 . . . cord-015369-72cjogxz 804 1 Laparoscopic laparoscopic JJ cord-015369-72cjogxz 804 2 liver liver NN cord-015369-72cjogxz 804 3 surgery surgery NN cord-015369-72cjogxz 804 4 has have VBZ cord-015369-72cjogxz 804 5 been be VBN cord-015369-72cjogxz 804 6 proven prove VBN cord-015369-72cjogxz 804 7 feasible feasible JJ cord-015369-72cjogxz 804 8 and and CC cord-015369-72cjogxz 804 9 safe safe JJ cord-015369-72cjogxz 804 10 for for IN cord-015369-72cjogxz 804 11 the the DT cord-015369-72cjogxz 804 12 treatment treatment NN cord-015369-72cjogxz 804 13 of of IN cord-015369-72cjogxz 804 14 benign benign JJ cord-015369-72cjogxz 804 15 and and CC cord-015369-72cjogxz 804 16 malign malign JJ cord-015369-72cjogxz 804 17 liver liver NN cord-015369-72cjogxz 804 18 diseases disease NNS cord-015369-72cjogxz 804 19 . . . cord-015369-72cjogxz 805 1 However however RB cord-015369-72cjogxz 805 2 , , , cord-015369-72cjogxz 805 3 the the DT cord-015369-72cjogxz 805 4 complexity complexity NN cord-015369-72cjogxz 805 5 of of IN cord-015369-72cjogxz 805 6 resections resection NNS cord-015369-72cjogxz 805 7 and and CC cord-015369-72cjogxz 805 8 the the DT cord-015369-72cjogxz 805 9 limitations limitation NNS cord-015369-72cjogxz 805 10 in in IN cord-015369-72cjogxz 805 11 instrumentation instrumentation NN cord-015369-72cjogxz 805 12 hamper hamper NN cord-015369-72cjogxz 805 13 broad broad JJ cord-015369-72cjogxz 805 14 acceptance acceptance NN cord-015369-72cjogxz 805 15 for for IN cord-015369-72cjogxz 805 16 advanced advanced JJ cord-015369-72cjogxz 805 17 liver liver NN cord-015369-72cjogxz 805 18 surgery surgery NN cord-015369-72cjogxz 805 19 . . . cord-015369-72cjogxz 806 1 Herein herein RB cord-015369-72cjogxz 806 2 we -PRON- PRP cord-015369-72cjogxz 806 3 describe describe VBP cord-015369-72cjogxz 806 4 different different JJ cord-015369-72cjogxz 806 5 technical technical JJ cord-015369-72cjogxz 806 6 procedures procedure NNS cord-015369-72cjogxz 806 7 for for IN cord-015369-72cjogxz 806 8 minimally minimally RB cord-015369-72cjogxz 806 9 invasive invasive JJ cord-015369-72cjogxz 806 10 liver liver NN cord-015369-72cjogxz 806 11 surgery surgery NN cord-015369-72cjogxz 806 12 adding add VBG cord-015369-72cjogxz 806 13 safety safety NN cord-015369-72cjogxz 806 14 to to IN cord-015369-72cjogxz 806 15 major major JJ cord-015369-72cjogxz 806 16 laparoscopic laparoscopic JJ cord-015369-72cjogxz 806 17 hepatic hepatic JJ cord-015369-72cjogxz 806 18 resections resection NNS cord-015369-72cjogxz 806 19 . . . cord-015369-72cjogxz 807 1 Methods method NNS cord-015369-72cjogxz 807 2 . . . cord-015369-72cjogxz 808 1 Three three CD cord-015369-72cjogxz 808 2 patients patient NNS cord-015369-72cjogxz 808 3 ( ( -LRB- cord-015369-72cjogxz 808 4 2 2 CD cord-015369-72cjogxz 808 5 female female JJ cord-015369-72cjogxz 808 6 , , , cord-015369-72cjogxz 808 7 1 1 CD cord-015369-72cjogxz 808 8 male male NN cord-015369-72cjogxz 808 9 ; ; : cord-015369-72cjogxz 808 10 age age NN cord-015369-72cjogxz 808 11 : : : cord-015369-72cjogxz 808 12 66 66 CD cord-015369-72cjogxz 808 13 , , , cord-015369-72cjogxz 808 14 70 70 CD cord-015369-72cjogxz 808 15 , , , cord-015369-72cjogxz 808 16 84 84 CD cord-015369-72cjogxz 808 17 ) ) -RRB- cord-015369-72cjogxz 808 18 underwent undergo VBD cord-015369-72cjogxz 808 19 laparoscopic laparoscopic JJ cord-015369-72cjogxz 808 20 major major JJ cord-015369-72cjogxz 808 21 hepatic hepatic JJ cord-015369-72cjogxz 808 22 resections resection NNS cord-015369-72cjogxz 808 23 for for IN cord-015369-72cjogxz 808 24 primary primary JJ cord-015369-72cjogxz 808 25 and and CC cord-015369-72cjogxz 808 26 secondary secondary JJ cord-015369-72cjogxz 808 27 liver liver NN cord-015369-72cjogxz 808 28 malignancy malignancy NN cord-015369-72cjogxz 808 29 , , , cord-015369-72cjogxz 808 30 respectively respectively RB cord-015369-72cjogxz 808 31 . . . cord-015369-72cjogxz 809 1 The the DT cord-015369-72cjogxz 809 2 entire entire JJ cord-015369-72cjogxz 809 3 operation operation NN cord-015369-72cjogxz 809 4 was be VBD cord-015369-72cjogxz 809 5 guided guide VBN cord-015369-72cjogxz 809 6 by by IN cord-015369-72cjogxz 809 7 laparoscopic laparoscopic JJ cord-015369-72cjogxz 809 8 ultrasound ultrasound NN cord-015369-72cjogxz 809 9 to to TO cord-015369-72cjogxz 809 10 define define VB cord-015369-72cjogxz 809 11 the the DT cord-015369-72cjogxz 809 12 resection resection NN cord-015369-72cjogxz 809 13 planes plane NNS cord-015369-72cjogxz 809 14 . . . cord-015369-72cjogxz 810 1 Vascular vascular JJ cord-015369-72cjogxz 810 2 control control NN cord-015369-72cjogxz 810 3 of of IN cord-015369-72cjogxz 810 4 the the DT cord-015369-72cjogxz 810 5 hepatic hepatic JJ cord-015369-72cjogxz 810 6 inflow inflow NN cord-015369-72cjogxz 810 7 and and CC cord-015369-72cjogxz 810 8 outflow outflow NN cord-015369-72cjogxz 810 9 was be VBD cord-015369-72cjogxz 810 10 achieved achieve VBN cord-015369-72cjogxz 810 11 for for IN cord-015369-72cjogxz 810 12 the the DT cord-015369-72cjogxz 810 13 impaired impaired JJ cord-015369-72cjogxz 810 14 part part NN cord-015369-72cjogxz 810 15 of of IN cord-015369-72cjogxz 810 16 the the DT cord-015369-72cjogxz 810 17 liver liver NN cord-015369-72cjogxz 810 18 . . . cord-015369-72cjogxz 811 1 Dissection dissection NN cord-015369-72cjogxz 811 2 of of IN cord-015369-72cjogxz 811 3 the the DT cord-015369-72cjogxz 811 4 parenchyma parenchyma NN cord-015369-72cjogxz 811 5 was be VBD cord-015369-72cjogxz 811 6 carried carry VBN cord-015369-72cjogxz 811 7 out out RP cord-015369-72cjogxz 811 8 utilizing utilize VBG cord-015369-72cjogxz 811 9 in in IN cord-015369-72cjogxz 811 10 particular particular JJ cord-015369-72cjogxz 811 11 laparoscopic laparoscopic JJ cord-015369-72cjogxz 811 12 radiofrequency radiofrequency NN cord-015369-72cjogxz 811 13 ablation ablation NN cord-015369-72cjogxz 811 14 , , , cord-015369-72cjogxz 811 15 the the DT cord-015369-72cjogxz 811 16 harmonic harmonic JJ cord-015369-72cjogxz 811 17 scalpel scalpel NN cord-015369-72cjogxz 811 18 and and CC cord-015369-72cjogxz 811 19 laparoscopic laparoscopic JJ cord-015369-72cjogxz 811 20 staplers stapler NNS cord-015369-72cjogxz 811 21 . . . cord-015369-72cjogxz 812 1 Specimen specimen NN cord-015369-72cjogxz 812 2 were be VBD cord-015369-72cjogxz 812 3 retrieved retrieve VBN cord-015369-72cjogxz 812 4 in in IN cord-015369-72cjogxz 812 5 a a DT cord-015369-72cjogxz 812 6 bag bag NN cord-015369-72cjogxz 812 7 through through IN cord-015369-72cjogxz 812 8 an an DT cord-015369-72cjogxz 812 9 enlarged enlarged JJ cord-015369-72cjogxz 812 10 trocar trocar NN cord-015369-72cjogxz 812 11 incision incision NN cord-015369-72cjogxz 812 12 . . . cord-015369-72cjogxz 813 1 The the DT cord-015369-72cjogxz 813 2 technique technique NN cord-015369-72cjogxz 813 3 is be VBZ cord-015369-72cjogxz 813 4 discussed discuss VBN cord-015369-72cjogxz 813 5 . . . cord-015369-72cjogxz 814 1 Results result NNS cord-015369-72cjogxz 814 2 . . . cord-015369-72cjogxz 815 1 Laparoscopic laparoscopic JJ cord-015369-72cjogxz 815 2 liver liver NN cord-015369-72cjogxz 815 3 resection resection NN cord-015369-72cjogxz 815 4 was be VBD cord-015369-72cjogxz 815 5 completed complete VBN cord-015369-72cjogxz 815 6 in in IN cord-015369-72cjogxz 815 7 all all DT cord-015369-72cjogxz 815 8 patients patient NNS cord-015369-72cjogxz 815 9 . . . cord-015369-72cjogxz 816 1 The the DT cord-015369-72cjogxz 816 2 operative operative JJ cord-015369-72cjogxz 816 3 time time NN cord-015369-72cjogxz 816 4 was be VBD cord-015369-72cjogxz 816 5 125 125 CD cord-015369-72cjogxz 816 6 - - SYM cord-015369-72cjogxz 816 7 170 170 CD cord-015369-72cjogxz 816 8 min min NN cord-015369-72cjogxz 816 9 . . . cord-015369-72cjogxz 817 1 No no DT cord-015369-72cjogxz 817 2 intraoperative intraoperative JJ cord-015369-72cjogxz 817 3 adverse adverse JJ cord-015369-72cjogxz 817 4 events event NNS cord-015369-72cjogxz 817 5 were be VBD cord-015369-72cjogxz 817 6 observed observe VBN cord-015369-72cjogxz 817 7 . . . cord-015369-72cjogxz 818 1 Blood blood NN cord-015369-72cjogxz 818 2 loss loss NN cord-015369-72cjogxz 818 3 yielded yield VBD cord-015369-72cjogxz 818 4 insignificant insignificant JJ cord-015369-72cjogxz 818 5 in in IN cord-015369-72cjogxz 818 6 2 2 CD cord-015369-72cjogxz 818 7 and and CC cord-015369-72cjogxz 818 8 300 300 CD cord-015369-72cjogxz 818 9 ml ml NNS cord-015369-72cjogxz 818 10 in in IN cord-015369-72cjogxz 818 11 one one CD cord-015369-72cjogxz 818 12 patient patient NN cord-015369-72cjogxz 818 13 , , , cord-015369-72cjogxz 818 14 respectively respectively RB cord-015369-72cjogxz 818 15 . . . cord-015369-72cjogxz 819 1 Specimen specimen NN cord-015369-72cjogxz 819 2 were be VBD cord-015369-72cjogxz 819 3 retrieved retrieve VBN cord-015369-72cjogxz 819 4 in in IN cord-015369-72cjogxz 819 5 a a DT cord-015369-72cjogxz 819 6 bag bag NN cord-015369-72cjogxz 819 7 through through IN cord-015369-72cjogxz 819 8 a a DT cord-015369-72cjogxz 819 9 widened widen VBN cord-015369-72cjogxz 819 10 trocar trocar NN cord-015369-72cjogxz 819 11 incision incision NN cord-015369-72cjogxz 819 12 . . . cord-015369-72cjogxz 820 1 No no DT cord-015369-72cjogxz 820 2 significant significant JJ cord-015369-72cjogxz 820 3 perioperative perioperative JJ cord-015369-72cjogxz 820 4 complication complication NN cord-015369-72cjogxz 820 5 was be VBD cord-015369-72cjogxz 820 6 noticed notice VBN cord-015369-72cjogxz 820 7 . . . cord-015369-72cjogxz 821 1 Histological histological JJ cord-015369-72cjogxz 821 2 evaluation evaluation NN cord-015369-72cjogxz 821 3 revealed reveal VBD cord-015369-72cjogxz 821 4 sufficient sufficient JJ cord-015369-72cjogxz 821 5 resection resection NN cord-015369-72cjogxz 821 6 margins margin NNS cord-015369-72cjogxz 821 7 to to IN cord-015369-72cjogxz 821 8 the the DT cord-015369-72cjogxz 821 9 malignant malignant JJ cord-015369-72cjogxz 821 10 tumours tumour NNS cord-015369-72cjogxz 821 11 . . . cord-015369-72cjogxz 822 1 Oral oral JJ cord-015369-72cjogxz 822 2 diet diet NN cord-015369-72cjogxz 822 3 was be VBD cord-015369-72cjogxz 822 4 resumed resume VBN cord-015369-72cjogxz 822 5 on on IN cord-015369-72cjogxz 822 6 the the DT cord-015369-72cjogxz 822 7 first first JJ cord-015369-72cjogxz 822 8 postoperative postoperative JJ cord-015369-72cjogxz 822 9 day day NN cord-015369-72cjogxz 822 10 . . . cord-015369-72cjogxz 823 1 Patients patient NNS cord-015369-72cjogxz 823 2 were be VBD cord-015369-72cjogxz 823 3 discharged discharge VBN cord-015369-72cjogxz 823 4 on on IN cord-015369-72cjogxz 823 5 day day NN cord-015369-72cjogxz 823 6 16 16 CD cord-015369-72cjogxz 823 7 , , , cord-015369-72cjogxz 823 8 23 23 CD cord-015369-72cjogxz 823 9 and and CC cord-015369-72cjogxz 823 10 45 45 CD cord-015369-72cjogxz 823 11 ( ( -LRB- cord-015369-72cjogxz 823 12 due due IN cord-015369-72cjogxz 823 13 to to IN cord-015369-72cjogxz 823 14 additional additional JJ cord-015369-72cjogxz 823 15 surgery surgery NN cord-015369-72cjogxz 823 16 not not RB cord-015369-72cjogxz 823 17 related relate VBN cord-015369-72cjogxz 823 18 to to IN cord-015369-72cjogxz 823 19 the the DT cord-015369-72cjogxz 823 20 liver liver NN cord-015369-72cjogxz 823 21 resection resection NN cord-015369-72cjogxz 823 22 ) ) -RRB- cord-015369-72cjogxz 823 23 . . . cord-015369-72cjogxz 824 1 Conclusions conclusion NNS cord-015369-72cjogxz 824 2 . . . cord-015369-72cjogxz 825 1 We -PRON- PRP cord-015369-72cjogxz 825 2 present present VBP cord-015369-72cjogxz 825 3 our -PRON- PRP$ cord-015369-72cjogxz 825 4 technique technique NN cord-015369-72cjogxz 825 5 for for IN cord-015369-72cjogxz 825 6 laparoscopic laparoscopic JJ cord-015369-72cjogxz 825 7 major major JJ cord-015369-72cjogxz 825 8 hepatic hepatic JJ cord-015369-72cjogxz 825 9 resections resection NNS cord-015369-72cjogxz 825 10 by by IN cord-015369-72cjogxz 825 11 use use NN cord-015369-72cjogxz 825 12 of of IN cord-015369-72cjogxz 825 13 standard standard JJ cord-015369-72cjogxz 825 14 laparoscopic laparoscopic JJ cord-015369-72cjogxz 825 15 instrumentation instrumentation NN cord-015369-72cjogxz 825 16 . . . cord-015369-72cjogxz 826 1 Comparison comparison NN cord-015369-72cjogxz 826 2 of of IN cord-015369-72cjogxz 826 3 preoperative preoperative JJ cord-015369-72cjogxz 826 4 indocyanine indocyanine NN cord-015369-72cjogxz 826 5 green green JJ cord-015369-72cjogxz 826 6 clearance clearance NN cord-015369-72cjogxz 826 7 in in IN cord-015369-72cjogxz 826 8 patients patient NNS cord-015369-72cjogxz 826 9 with with IN cord-015369-72cjogxz 826 10 colorectal colorectal JJ cord-015369-72cjogxz 826 11 liver liver NN cord-015369-72cjogxz 826 12 metastases metastasis NNS cord-015369-72cjogxz 826 13 pretreated pretreate VBN cord-015369-72cjogxz 826 14 with with IN cord-015369-72cjogxz 826 15 systemic systemic JJ cord-015369-72cjogxz 826 16 chemotherapy chemotherapy NN cord-015369-72cjogxz 826 17 Background Background NNP cord-015369-72cjogxz 826 18 . . . cord-015369-72cjogxz 827 1 Preoperative preoperative JJ cord-015369-72cjogxz 827 2 systemic systemic JJ cord-015369-72cjogxz 827 3 chemotherapy chemotherapy NN cord-015369-72cjogxz 827 4 has have VBZ cord-015369-72cjogxz 827 5 become become VBN cord-015369-72cjogxz 827 6 an an DT cord-015369-72cjogxz 827 7 essential essential JJ cord-015369-72cjogxz 827 8 tool tool NN cord-015369-72cjogxz 827 9 in in IN cord-015369-72cjogxz 827 10 downsizing downsize VBG cord-015369-72cjogxz 827 11 colorectal colorectal JJ cord-015369-72cjogxz 827 12 liver liver NN cord-015369-72cjogxz 827 13 metastases metastasis NNS cord-015369-72cjogxz 827 14 ( ( -LRB- cord-015369-72cjogxz 827 15 CLM CLM NNP cord-015369-72cjogxz 827 16 ) ) -RRB- cord-015369-72cjogxz 827 17 , , , cord-015369-72cjogxz 827 18 helping help VBG cord-015369-72cjogxz 827 19 to to TO cord-015369-72cjogxz 827 20 render render VB cord-015369-72cjogxz 827 21 patients patient NNS cord-015369-72cjogxz 827 22 with with IN cord-015369-72cjogxz 827 23 initially initially RB cord-015369-72cjogxz 827 24 irresectable irresectable NNP cord-015369-72cjogxz 827 25 disease disease NN cord-015369-72cjogxz 827 26 resectable resectable NNP cord-015369-72cjogxz 827 27 and and CC cord-015369-72cjogxz 827 28 to to TO cord-015369-72cjogxz 827 29 prolong prolong VB cord-015369-72cjogxz 827 30 progression progression NN cord-015369-72cjogxz 827 31 free free JJ cord-015369-72cjogxz 827 32 survival survival NN cord-015369-72cjogxz 827 33 in in IN cord-015369-72cjogxz 827 34 initially initially RB cord-015369-72cjogxz 827 35 resectable resectable JJ cord-015369-72cjogxz 827 36 patients patient NNS cord-015369-72cjogxz 827 37 . . . cord-015369-72cjogxz 828 1 Histopathologic Histopathologic NNP cord-015369-72cjogxz 828 2 examinations examination NNS cord-015369-72cjogxz 828 3 of of IN cord-015369-72cjogxz 828 4 resected resected JJ cord-015369-72cjogxz 828 5 non non JJ cord-015369-72cjogxz 828 6 - - JJ cord-015369-72cjogxz 828 7 tumoral tumoral JJ cord-015369-72cjogxz 828 8 liver liver NN cord-015369-72cjogxz 828 9 tissue tissue NN cord-015369-72cjogxz 828 10 have have VBP cord-015369-72cjogxz 828 11 raised raise VBN cord-015369-72cjogxz 828 12 concerns concern NNS cord-015369-72cjogxz 828 13 about about IN cord-015369-72cjogxz 828 14 chemotherapy chemotherapy NN cord-015369-72cjogxz 828 15 - - HYPH cord-015369-72cjogxz 828 16 associated associate VBN cord-015369-72cjogxz 828 17 liver liver NN cord-015369-72cjogxz 828 18 injury injury NN cord-015369-72cjogxz 828 19 , , , cord-015369-72cjogxz 828 20 which which WDT cord-015369-72cjogxz 828 21 might may MD cord-015369-72cjogxz 828 22 impair impair VB cord-015369-72cjogxz 828 23 the the DT cord-015369-72cjogxz 828 24 function function NN cord-015369-72cjogxz 828 25 of of IN cord-015369-72cjogxz 828 26 the the DT cord-015369-72cjogxz 828 27 remnant remnant JJ cord-015369-72cjogxz 828 28 liver liver NN cord-015369-72cjogxz 828 29 . . . cord-015369-72cjogxz 829 1 We -PRON- PRP cord-015369-72cjogxz 829 2 therefore therefore RB cord-015369-72cjogxz 829 3 tried try VBD cord-015369-72cjogxz 829 4 to to TO cord-015369-72cjogxz 829 5 evaluate evaluate VB cord-015369-72cjogxz 829 6 whether whether IN cord-015369-72cjogxz 829 7 indocyanine indocyanine NN cord-015369-72cjogxz 829 8 green green JJ cord-015369-72cjogxz 829 9 plasma plasma NN cord-015369-72cjogxz 829 10 dilution dilution NN cord-015369-72cjogxz 829 11 rate rate NN cord-015369-72cjogxz 829 12 ( ( -LRB- cord-015369-72cjogxz 829 13 PDR PDR NNP cord-015369-72cjogxz 829 14 , , , cord-015369-72cjogxz 829 15 % % NN cord-015369-72cjogxz 829 16 Á á NN cord-015369-72cjogxz 829 17 min min NN cord-015369-72cjogxz 829 18 À1 À1 NNP cord-015369-72cjogxz 829 19 ) ) -RRB- cord-015369-72cjogxz 829 20 , , , cord-015369-72cjogxz 829 21 which which WDT cord-015369-72cjogxz 829 22 can can MD cord-015369-72cjogxz 829 23 easily easily RB cord-015369-72cjogxz 829 24 be be VB cord-015369-72cjogxz 829 25 measured measure VBN cord-015369-72cjogxz 829 26 preoperatively preoperatively RB cord-015369-72cjogxz 829 27 , , , cord-015369-72cjogxz 829 28 helps help VBZ cord-015369-72cjogxz 829 29 to to TO cord-015369-72cjogxz 829 30 assess assess VB cord-015369-72cjogxz 829 31 chemotherapy chemotherapy NN cord-015369-72cjogxz 829 32 - - HYPH cord-015369-72cjogxz 829 33 induced induce VBN cord-015369-72cjogxz 829 34 liver liver NN cord-015369-72cjogxz 829 35 damage damage NN cord-015369-72cjogxz 829 36 . . . cord-015369-72cjogxz 830 1 Methods method NNS cord-015369-72cjogxz 830 2 and and CC cord-015369-72cjogxz 830 3 results result NNS cord-015369-72cjogxz 830 4 . . . cord-015369-72cjogxz 831 1 Data datum NNS cord-015369-72cjogxz 831 2 of of IN cord-015369-72cjogxz 831 3 135 135 CD cord-015369-72cjogxz 831 4 liver liver NN cord-015369-72cjogxz 831 5 resections resection NNS cord-015369-72cjogxz 831 6 for for IN cord-015369-72cjogxz 831 7 CLM CLM NNP cord-015369-72cjogxz 831 8 performed perform VBN cord-015369-72cjogxz 831 9 between between IN cord-015369-72cjogxz 831 10 january january NNP cord-015369-72cjogxz 831 11 2004 2004 CD cord-015369-72cjogxz 831 12 and and CC cord-015369-72cjogxz 831 13 december december NNP cord-015369-72cjogxz 831 14 2007 2007 CD cord-015369-72cjogxz 831 15 were be VBD cord-015369-72cjogxz 831 16 analyzed analyze VBN cord-015369-72cjogxz 831 17 . . . cord-015369-72cjogxz 832 1 Onehundred onehundre VBN cord-015369-72cjogxz 832 2 - - HYPH cord-015369-72cjogxz 832 3 fifteen fifteen CD cord-015369-72cjogxz 832 4 patients patient NNS cord-015369-72cjogxz 832 5 were be VBD cord-015369-72cjogxz 832 6 treated treat VBN cord-015369-72cjogxz 832 7 with with IN cord-015369-72cjogxz 832 8 chemotherapy chemotherapy NN cord-015369-72cjogxz 832 9 prior prior RB cord-015369-72cjogxz 832 10 to to IN cord-015369-72cjogxz 832 11 surgery surgery NN cord-015369-72cjogxz 832 12 , , , cord-015369-72cjogxz 832 13 20 20 CD cord-015369-72cjogxz 832 14 patients patient NNS cord-015369-72cjogxz 832 15 were be VBD cord-015369-72cjogxz 832 16 resected resect VBN cord-015369-72cjogxz 832 17 without without IN cord-015369-72cjogxz 832 18 pretreatment pretreatment NN cord-015369-72cjogxz 832 19 . . . cord-015369-72cjogxz 833 1 Patients patient NNS cord-015369-72cjogxz 833 2 who who WP cord-015369-72cjogxz 833 3 received receive VBD cord-015369-72cjogxz 833 4 preoperative preoperative JJ cord-015369-72cjogxz 833 5 chemotherapy chemotherapy NN cord-015369-72cjogxz 833 6 had have VBD cord-015369-72cjogxz 833 7 a a DT cord-015369-72cjogxz 833 8 significant significant JJ cord-015369-72cjogxz 833 9 lower low JJR cord-015369-72cjogxz 833 10 PDR PDR NNP cord-015369-72cjogxz 833 11 ( ( -LRB- cord-015369-72cjogxz 833 12 19.3 19.3 CD cord-015369-72cjogxz 833 13 AE AE NNP cord-015369-72cjogxz 833 14 5,4 5,4 CD cord-015369-72cjogxz 833 15 versus versus IN cord-015369-72cjogxz 833 16 23.4 23.4 CD cord-015369-72cjogxz 833 17 AE AE NNP cord-015369-72cjogxz 833 18 3.8 3.8 CD cord-015369-72cjogxz 833 19 ; ; : cord-015369-72cjogxz 833 20 p p NN cord-015369-72cjogxz 833 21 ¼ ¼ CD cord-015369-72cjogxz 833 22 0.02 0.02 CD cord-015369-72cjogxz 833 23 ) ) -RRB- cord-015369-72cjogxz 833 24 reflecting reflect VBG cord-015369-72cjogxz 833 25 an an DT cord-015369-72cjogxz 833 26 impaired impaired JJ cord-015369-72cjogxz 833 27 liver liver NN cord-015369-72cjogxz 833 28 function function NN cord-015369-72cjogxz 833 29 . . . cord-015369-72cjogxz 834 1 The the DT cord-015369-72cjogxz 834 2 percentage percentage NN cord-015369-72cjogxz 834 3 of of IN cord-015369-72cjogxz 834 4 subjects subject NNS cord-015369-72cjogxz 834 5 with with IN cord-015369-72cjogxz 834 6 an an DT cord-015369-72cjogxz 834 7 abnormal abnormal JJ cord-015369-72cjogxz 834 8 PDR PDR NNP cord-015369-72cjogxz 834 9 ( ( -LRB- cord-015369-72cjogxz 834 10 PDR PDR NNP cord-015369-72cjogxz 834 11 18 18 CD cord-015369-72cjogxz 834 12 ) ) -RRB- cord-015369-72cjogxz 834 13 was be VBD cord-015369-72cjogxz 834 14 significantly significantly RB cord-015369-72cjogxz 834 15 higher high JJR cord-015369-72cjogxz 834 16 among among IN cord-015369-72cjogxz 834 17 those those DT cord-015369-72cjogxz 834 18 who who WP cord-015369-72cjogxz 834 19 were be VBD cord-015369-72cjogxz 834 20 treated treat VBN cord-015369-72cjogxz 834 21 with with IN cord-015369-72cjogxz 834 22 chemotherapy chemotherapy NN cord-015369-72cjogxz 834 23 prior prior RB cord-015369-72cjogxz 834 24 to to IN cord-015369-72cjogxz 834 25 liver liver NN cord-015369-72cjogxz 834 26 resection resection NN cord-015369-72cjogxz 834 27 ( ( -LRB- cord-015369-72cjogxz 834 28 48.7 48.7 CD cord-015369-72cjogxz 834 29 % % NN cord-015369-72cjogxz 834 30 versus versus IN cord-015369-72cjogxz 834 31 5 5 CD cord-015369-72cjogxz 834 32 % % NN cord-015369-72cjogxz 834 33 ; ; : cord-015369-72cjogxz 834 34 p p NN cord-015369-72cjogxz 834 35 < < XX cord-015369-72cjogxz 834 36 0.001 0.001 CD cord-015369-72cjogxz 834 37 ) ) -RRB- cord-015369-72cjogxz 834 38 . . . cord-015369-72cjogxz 835 1 Patients patient NNS cord-015369-72cjogxz 835 2 with with IN cord-015369-72cjogxz 835 3 a a DT cord-015369-72cjogxz 835 4 PDR PDR NNP cord-015369-72cjogxz 835 5 18 18 CD cord-015369-72cjogxz 835 6 stayed stay VBD cord-015369-72cjogxz 835 7 longer long RBR cord-015369-72cjogxz 835 8 in in IN cord-015369-72cjogxz 835 9 the the DT cord-015369-72cjogxz 835 10 intensive intensive JJ cord-015369-72cjogxz 835 11 care care NN cord-015369-72cjogxz 835 12 unit unit NN cord-015369-72cjogxz 835 13 compared compare VBN cord-015369-72cjogxz 835 14 to to IN cord-015369-72cjogxz 835 15 those those DT cord-015369-72cjogxz 835 16 with with IN cord-015369-72cjogxz 835 17 a a DT cord-015369-72cjogxz 835 18 PDR PDR NNP cord-015369-72cjogxz 835 19 > > XX cord-015369-72cjogxz 836 1 18 18 CD cord-015369-72cjogxz 836 2 ( ( -LRB- cord-015369-72cjogxz 836 3 2.0 2.0 CD cord-015369-72cjogxz 836 4 AE AE NNP cord-015369-72cjogxz 836 5 2.0 2.0 CD cord-015369-72cjogxz 836 6 versus versus IN cord-015369-72cjogxz 836 7 0.9 0.9 CD cord-015369-72cjogxz 836 8 AE AE NNP cord-015369-72cjogxz 836 9 0.9 0.9 CD cord-015369-72cjogxz 836 10 ; ; : cord-015369-72cjogxz 836 11 p p NN cord-015369-72cjogxz 836 12 ¼ ¼ CD cord-015369-72cjogxz 836 13 0.03 0.03 CD cord-015369-72cjogxz 836 14 ) ) -RRB- cord-015369-72cjogxz 837 1 and and CC cord-015369-72cjogxz 837 2 had have VBD cord-015369-72cjogxz 837 3 a a DT cord-015369-72cjogxz 837 4 significantly significantly RB cord-015369-72cjogxz 837 5 longer long JJR cord-015369-72cjogxz 837 6 postoperative postoperative JJ cord-015369-72cjogxz 837 7 hospital hospital NN cord-015369-72cjogxz 837 8 stay stay NN cord-015369-72cjogxz 837 9 ( ( -LRB- cord-015369-72cjogxz 837 10 10.0 10.0 CD cord-015369-72cjogxz 837 11 AE AE NNP cord-015369-72cjogxz 837 12 5.7 5.7 CD cord-015369-72cjogxz 837 13 versus versus IN cord-015369-72cjogxz 837 14 7.4 7.4 CD cord-015369-72cjogxz 837 15 AE AE NNP cord-015369-72cjogxz 837 16 2.9 2.9 CD cord-015369-72cjogxz 837 17 ; ; : cord-015369-72cjogxz 837 18 p p NN cord-015369-72cjogxz 837 19 ¼ ¼ CD cord-015369-72cjogxz 837 20 0.009 0.009 CD cord-015369-72cjogxz 837 21 ) ) -RRB- cord-015369-72cjogxz 837 22 . . . cord-015369-72cjogxz 838 1 The the DT cord-015369-72cjogxz 838 2 incidence incidence NN cord-015369-72cjogxz 838 3 of of IN cord-015369-72cjogxz 838 4 postoperative postoperative JJ cord-015369-72cjogxz 838 5 complications complication NNS cord-015369-72cjogxz 838 6 was be VBD cord-015369-72cjogxz 838 7 increased increase VBN cord-015369-72cjogxz 838 8 in in IN cord-015369-72cjogxz 838 9 those those DT cord-015369-72cjogxz 838 10 with with IN cord-015369-72cjogxz 838 11 an an DT cord-015369-72cjogxz 838 12 abnormal abnormal JJ cord-015369-72cjogxz 838 13 PDR PDR NNP cord-015369-72cjogxz 838 14 ( ( -LRB- cord-015369-72cjogxz 838 15 34.1 34.1 CD cord-015369-72cjogxz 838 16 % % NN cord-015369-72cjogxz 838 17 versus versus IN cord-015369-72cjogxz 838 18 8.3 8.3 CD cord-015369-72cjogxz 838 19 % % NN cord-015369-72cjogxz 838 20 ; ; : cord-015369-72cjogxz 838 21 p p NN cord-015369-72cjogxz 838 22 ¼ ¼ CD cord-015369-72cjogxz 838 23 0.01 0.01 CD cord-015369-72cjogxz 838 24 ) ) -RRB- cord-015369-72cjogxz 838 25 . . . cord-015369-72cjogxz 839 1 Conclusions conclusion NNS cord-015369-72cjogxz 839 2 . . . cord-015369-72cjogxz 840 1 Assessing assess VBG cord-015369-72cjogxz 840 2 the the DT cord-015369-72cjogxz 840 3 PDR PDR NNP cord-015369-72cjogxz 840 4 preoperatively preoperatively NN cord-015369-72cjogxz 840 5 may may MD cord-015369-72cjogxz 840 6 help help VB cord-015369-72cjogxz 840 7 to to TO cord-015369-72cjogxz 840 8 indentify indentify VB cord-015369-72cjogxz 840 9 patients patient NNS cord-015369-72cjogxz 840 10 with with IN cord-015369-72cjogxz 840 11 an an DT cord-015369-72cjogxz 840 12 impaired impaired JJ cord-015369-72cjogxz 840 13 liver liver NN cord-015369-72cjogxz 840 14 function function NN cord-015369-72cjogxz 840 15 after after IN cord-015369-72cjogxz 840 16 preoperative preoperative JJ cord-015369-72cjogxz 840 17 chemotherapy chemotherapy NN cord-015369-72cjogxz 840 18 . . . cord-015369-72cjogxz 841 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 841 2 . . . cord-015369-72cjogxz 842 1 Die die VB cord-015369-72cjogxz 843 1 Radiofrequenztherapie Radiofrequenztherapie NNP cord-015369-72cjogxz 843 2 ist ist NN cord-015369-72cjogxz 843 3 mittlerweile mittlerweile FW cord-015369-72cjogxz 843 4 ein ein NNP cord-015369-72cjogxz 843 5 etabliertes etablierte NNS cord-015369-72cjogxz 844 1 Verfahren Verfahren NNP cord-015369-72cjogxz 844 2 zur zur NNP cord-015369-72cjogxz 844 3 lokalen lokalen NNP cord-015369-72cjogxz 844 4 Tumorkontrolle Tumorkontrolle NNP cord-015369-72cjogxz 844 5 bei bei NNP cord-015369-72cjogxz 844 6 nicht nicht NNP cord-015369-72cjogxz 844 7 oberflächennahe oberflächennahe NNP cord-015369-72cjogxz 844 8 lokalisierten lokalisierten NNP cord-015369-72cjogxz 844 9 primären primären NNP cord-015369-72cjogxz 844 10 und und IN cord-015369-72cjogxz 844 11 sekundären sekundären NNP cord-015369-72cjogxz 844 12 Lebertumore Lebertumore NNP cord-015369-72cjogxz 844 13 mit mit NNP cord-015369-72cjogxz 844 14 einer einer NNP cord-015369-72cjogxz 844 15 maximalen maximalen NNP cord-015369-72cjogxz 844 16 Größe Größe NNP cord-015369-72cjogxz 844 17 von von NNP cord-015369-72cjogxz 844 18 3 3 CD cord-015369-72cjogxz 844 19 cm cm NN cord-015369-72cjogxz 844 20 . . . cord-015369-72cjogxz 845 1 Wir Wir NNP cord-015369-72cjogxz 845 2 2005 2005 CD cord-015369-72cjogxz 845 3 eine eine NNP cord-015369-72cjogxz 845 4 Technik Technik NNP cord-015369-72cjogxz 845 5 entwickelt entwickelt NNP cord-015369-72cjogxz 845 6 , , , cord-015369-72cjogxz 845 7 die die VB cord-015369-72cjogxz 845 8 es es FW cord-015369-72cjogxz 845 9 ermöglicht ermöglicht FW cord-015369-72cjogxz 845 10 große große NNP cord-015369-72cjogxz 845 11 Tumore Tumore NNP cord-015369-72cjogxz 845 12 oberflächennahe oberflächennahe RB cord-015369-72cjogxz 846 1 und und IN cord-015369-72cjogxz 846 2 damit damit NNP cord-015369-72cjogxz 846 3 in in IN cord-015369-72cjogxz 846 4 unmittelbarer unmittelbarer NNP cord-015369-72cjogxz 847 1 Nachbarschaft Nachbarschaft NNP cord-015369-72cjogxz 847 2 zu zu NNP cord-015369-72cjogxz 847 3 anderen anderen NNP cord-015369-72cjogxz 847 4 Organen Organen NNP cord-015369-72cjogxz 847 5 , , , cord-015369-72cjogxz 847 6 wie wie NNP cord-015369-72cjogxz 847 7 Magen Magen NNP cord-015369-72cjogxz 847 8 , , , cord-015369-72cjogxz 847 9 Colon colon NN cord-015369-72cjogxz 847 10 , , , cord-015369-72cjogxz 847 11 Niere Niere NNP cord-015369-72cjogxz 847 12 oder oder NNP cord-015369-72cjogxz 847 13 Zwerchfell Zwerchfell NNP cord-015369-72cjogxz 847 14 laparoskopisch laparoskopisch NN cord-015369-72cjogxz 848 1 so so RB cord-015369-72cjogxz 848 2 zu zu NNP cord-015369-72cjogxz 848 3 isolieren isolieren NNP cord-015369-72cjogxz 849 1 , , , cord-015369-72cjogxz 849 2 so so RB cord-015369-72cjogxz 849 3 dass dass NNP cord-015369-72cjogxz 849 4 sie sie NNP cord-015369-72cjogxz 849 5 anschliessend anschliessend NNP cord-015369-72cjogxz 849 6 computerunterstützt computerunterstützt VBD cord-015369-72cjogxz 849 7 abladierbar abladierbar NNP cord-015369-72cjogxz 849 8 sind sind NNP cord-015369-72cjogxz 849 9 . . . cord-015369-72cjogxz 850 1 Die die VB cord-015369-72cjogxz 850 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 850 3 und und IN cord-015369-72cjogxz 851 1 Komplikationen Komplikationen NNP cord-015369-72cjogxz 851 2 werden werden NNP cord-015369-72cjogxz 851 3 hier hier NNP cord-015369-72cjogxz 851 4 präsentiert präsentiert NNP cord-015369-72cjogxz 851 5 . . . cord-015369-72cjogxz 852 1 Methodik Methodik NNP cord-015369-72cjogxz 852 2 . . . cord-015369-72cjogxz 853 1 Alle Alle NNP cord-015369-72cjogxz 853 2 Patienten Patienten NNP cord-015369-72cjogxz 853 3 , , , cord-015369-72cjogxz 853 4 die die VBP cord-015369-72cjogxz 853 5 i -PRON- PRP cord-015369-72cjogxz 853 6 m be VBP cord-015369-72cjogxz 853 7 Zeitraum Zeitraum NNP cord-015369-72cjogxz 853 8 von von NNP cord-015369-72cjogxz 853 9 12/2005 12/2005 CD cord-015369-72cjogxz 853 10 bis bis NNP cord-015369-72cjogxz 853 11 12/2008 12/2008 CD cord-015369-72cjogxz 853 12 nach nach NNP cord-015369-72cjogxz 853 13 laparoskopischem laparoskopischem NNP cord-015369-72cjogxz 853 14 liver liver NN cord-015369-72cjogxz 853 15 packing pack VBG cord-015369-72cjogxz 853 16 radiofrequenzabladiert radiofrequenzabladiert NNP cord-015369-72cjogxz 853 17 wurden wurden NNP cord-015369-72cjogxz 853 18 , , , cord-015369-72cjogxz 853 19 wurden wurden NNP cord-015369-72cjogxz 853 20 eingeschlossen eingeschlossen NNP cord-015369-72cjogxz 853 21 und und IN cord-015369-72cjogxz 853 22 retrospektiv retrospektiv NNP cord-015369-72cjogxz 853 23 analysiert analysiert NNP cord-015369-72cjogxz 853 24 . . . cord-015369-72cjogxz 854 1 Patientendaten Patientendaten NNP cord-015369-72cjogxz 854 2 , , , cord-015369-72cjogxz 854 3 Komplikationen Komplikationen NNP cord-015369-72cjogxz 854 4 , , , cord-015369-72cjogxz 854 5 und und NNP cord-015369-72cjogxz 855 1 Follow follow VB cord-015369-72cjogxz 855 2 - - HYPH cord-015369-72cjogxz 855 3 up up NN cord-015369-72cjogxz 856 1 sind sind NNP cord-015369-72cjogxz 856 2 dokumentiert dokumentiert NNP cord-015369-72cjogxz 856 3 worden worden NNP cord-015369-72cjogxz 856 4 . . . cord-015369-72cjogxz 857 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 857 2 . . . cord-015369-72cjogxz 858 1 42 42 CD cord-015369-72cjogxz 858 2 Patienten Patienten NNP cord-015369-72cjogxz 858 3 ( ( -LRB- cord-015369-72cjogxz 858 4 f f NNP cord-015369-72cjogxz 858 5 ¼ ¼ NNP cord-015369-72cjogxz 858 6 15 15 CD cord-015369-72cjogxz 858 7 , , , cord-015369-72cjogxz 858 8 m m NNP cord-015369-72cjogxz 858 9 ¼ ¼ NNP cord-015369-72cjogxz 858 10 27 27 CD cord-015369-72cjogxz 858 11 ) ) -RRB- cord-015369-72cjogxz 858 12 mit mit NNP cord-015369-72cjogxz 858 13 einem einem NNP cord-015369-72cjogxz 858 14 mittleren mittleren NNP cord-015369-72cjogxz 859 1 Alter alter VB cord-015369-72cjogxz 859 2 von von NNP cord-015369-72cjogxz 859 3 65.5 65.5 CD cord-015369-72cjogxz 859 4 Jahren Jahren NNP cord-015369-72cjogxz 859 5 sind sind NNP cord-015369-72cjogxz 860 1 i -PRON- PRP cord-015369-72cjogxz 860 2 m be VBP cord-015369-72cjogxz 860 3 Beobachtungszeitraum Beobachtungszeitraum NNP cord-015369-72cjogxz 860 4 wegen wegen NNP cord-015369-72cjogxz 860 5 eines eines NNP cord-015369-72cjogxz 860 6 CCC CCC NNP cord-015369-72cjogxz 860 7 ( ( -LRB- cord-015369-72cjogxz 860 8 n n NN cord-015369-72cjogxz 860 9 ¼ ¼ NNP cord-015369-72cjogxz 860 10 3 3 CD cord-015369-72cjogxz 860 11 ) ) -RRB- cord-015369-72cjogxz 860 12 , , , cord-015369-72cjogxz 860 13 HCC HCC NNP cord-015369-72cjogxz 860 14 ( ( -LRB- cord-015369-72cjogxz 860 15 n n NN cord-015369-72cjogxz 860 16 ¼ ¼ NNP cord-015369-72cjogxz 860 17 19 19 CD cord-015369-72cjogxz 860 18 ) ) -RRB- cord-015369-72cjogxz 860 19 und und RB cord-015369-72cjogxz 861 1 Metastasen Metastasen NNP cord-015369-72cjogxz 861 2 ( ( -LRB- cord-015369-72cjogxz 861 3 n n NNP cord-015369-72cjogxz 861 4 ¼ ¼ NNP cord-015369-72cjogxz 861 5 21 21 CD cord-015369-72cjogxz 861 6 , , , cord-015369-72cjogxz 861 7 Colon colon NN cord-015369-72cjogxz 861 8 , , , cord-015369-72cjogxz 861 9 Rektum Rektum NNP cord-015369-72cjogxz 861 10 , , , cord-015369-72cjogxz 861 11 Mamma Mamma NNP cord-015369-72cjogxz 861 12 , , , cord-015369-72cjogxz 861 13 Neuroendokrines Neuroendokrines NNP cord-015369-72cjogxz 861 14 Karzinom Karzinom NNP cord-015369-72cjogxz 861 15 , , , cord-015369-72cjogxz 861 16 Melanom Melanom NNPS cord-015369-72cjogxz 861 17 , , , cord-015369-72cjogxz 861 18 RCC RCC NNP cord-015369-72cjogxz 861 19 ) ) -RRB- cord-015369-72cjogxz 861 20 operiert operiert NNP cord-015369-72cjogxz 861 21 und und NNP cord-015369-72cjogxz 861 22 abladiert abladiert NNP cord-015369-72cjogxz 861 23 worden worden NNP cord-015369-72cjogxz 861 24 . . . cord-015369-72cjogxz 862 1 Die die VB cord-015369-72cjogxz 862 2 perioperative perioperative JJ cord-015369-72cjogxz 862 3 Mortalität Mortalität NNP cord-015369-72cjogxz 862 4 betrug betrug NNP cord-015369-72cjogxz 862 5 2,4 2,4 CD cord-015369-72cjogxz 862 6 % % NN cord-015369-72cjogxz 862 7 ( ( -LRB- cord-015369-72cjogxz 862 8 n n NN cord-015369-72cjogxz 862 9 ¼ ¼ NNP cord-015369-72cjogxz 862 10 1 1 CD cord-015369-72cjogxz 862 11 ) ) -RRB- cord-015369-72cjogxz 862 12 aufgrund aufgrund NNP cord-015369-72cjogxz 862 13 eines eines NNP cord-015369-72cjogxz 862 14 postoperativen postoperativen VBN cord-015369-72cjogxz 862 15 Leberversagens Leberversagens NNP cord-015369-72cjogxz 862 16 . . . cord-015369-72cjogxz 863 1 Die die VB cord-015369-72cjogxz 863 2 beobachtete beobachtete JJ cord-015369-72cjogxz 863 3 Morbidität Morbidität NNP cord-015369-72cjogxz 863 4 betrug betrug NNP cord-015369-72cjogxz 864 1 35,7 35,7 CD cord-015369-72cjogxz 864 2 % % NN cord-015369-72cjogxz 864 3 ( ( -LRB- cord-015369-72cjogxz 864 4 n n NN cord-015369-72cjogxz 864 5 ¼ ¼ NNP cord-015369-72cjogxz 864 6 15 15 CD cord-015369-72cjogxz 864 7 ) ) -RRB- cord-015369-72cjogxz 865 1 und und IN cord-015369-72cjogxz 865 2 beinhaltete beinhaltete NNP cord-015369-72cjogxz 865 3 Pulmonaembolien Pulmonaembolien NNP cord-015369-72cjogxz 865 4 , , , cord-015369-72cjogxz 866 1 Dü Dü NNP cord-015369-72cjogxz 866 2 nndarmverletzungen nndarmverletzungen NNP cord-015369-72cjogxz 866 3 mit mit NNP cord-015369-72cjogxz 866 4 intraoperativer intraoperativer NNP cord-015369-72cjogxz 866 5 Ü Ü NNP cord-015369-72cjogxz 866 6 bernähung bernähung NNP cord-015369-72cjogxz 866 7 , , , cord-015369-72cjogxz 866 8 MODS MODS NNP cord-015369-72cjogxz 866 9 , , , cord-015369-72cjogxz 866 10 ARDS ARDS NNP cord-015369-72cjogxz 866 11 , , , cord-015369-72cjogxz 866 12 Durchgangssyndrom Durchgangssyndrom NNP cord-015369-72cjogxz 866 13 , , , cord-015369-72cjogxz 866 14 cervikale cervikale NNP cord-015369-72cjogxz 866 15 Plexusläsion Plexusläsion NNP cord-015369-72cjogxz 866 16 , , , cord-015369-72cjogxz 866 17 intraparenchymatöse intraparenchymatöse NNP cord-015369-72cjogxz 866 18 Blutung Blutung NNP cord-015369-72cjogxz 866 19 mit mit NNP cord-015369-72cjogxz 866 20 angiographischer angiographischer NN cord-015369-72cjogxz 866 21 Blutstillung Blutstillung NNP cord-015369-72cjogxz 866 22 , , , cord-015369-72cjogxz 866 23 par par NN cord-015369-72cjogxz 866 24 - - HYPH cord-015369-72cjogxz 866 25 tielle tielle NN cord-015369-72cjogxz 866 26 Pfortaderthrombose Pfortaderthrombose NNP cord-015369-72cjogxz 866 27 , , , cord-015369-72cjogxz 866 28 Spätabszess Spätabszess NNP cord-015369-72cjogxz 866 29 und und IN cord-015369-72cjogxz 866 30 ein ein NNP cord-015369-72cjogxz 866 31 Erysipel Erysipel NNP cord-015369-72cjogxz 866 32 am be VBP cord-015369-72cjogxz 866 33 Unterarm Unterarm NNP cord-015369-72cjogxz 866 34 . . . cord-015369-72cjogxz 867 1 Leichtes Leichtes NNP cord-015369-72cjogxz 867 2 Fieber Fieber NNP cord-015369-72cjogxz 867 3 und und IN cord-015369-72cjogxz 867 4 transienter transienter NNP cord-015369-72cjogxz 868 1 Transaminasenanstieg Transaminasenanstieg NNP cord-015369-72cjogxz 868 2 trat trat NNP cord-015369-72cjogxz 868 3 bei bei NNP cord-015369-72cjogxz 868 4 allen allen NNP cord-015369-72cjogxz 868 5 Patienten Patienten NNP cord-015369-72cjogxz 868 6 auf auf NNP cord-015369-72cjogxz 868 7 . . . cord-015369-72cjogxz 869 1 Bei Bei NNP cord-015369-72cjogxz 869 2 2 2 CD cord-015369-72cjogxz 870 1 Patienten Patienten NNP cord-015369-72cjogxz 870 2 wurde wurde VBD cord-015369-72cjogxz 870 3 wegen wegen NNP cord-015369-72cjogxz 870 4 eines eines NNP cord-015369-72cjogxz 871 1 Rezidivs Rezidivs NNP cord-015369-72cjogxz 871 2 eine eine NNP cord-015369-72cjogxz 871 3 neuerliche neuerliche NN cord-015369-72cjogxz 871 4 RFT RFT NNP cord-015369-72cjogxz 871 5 mit mit NNP cord-015369-72cjogxz 871 6 liver liver NN cord-015369-72cjogxz 871 7 packing packing NN cord-015369-72cjogxz 871 8 notwendig notwendig NNP cord-015369-72cjogxz 871 9 , , , cord-015369-72cjogxz 871 10 5 5 CD cord-015369-72cjogxz 871 11 Patienten Patienten NNP cord-015369-72cjogxz 871 12 wurden wurden VBD cord-015369-72cjogxz 871 13 ohne ohne NNP cord-015369-72cjogxz 871 14 Packing Packing NNP cord-015369-72cjogxz 871 15 ein ein NNP cord-015369-72cjogxz 871 16 zweites zweites NNP cord-015369-72cjogxz 871 17 mal mal NNP cord-015369-72cjogxz 871 18 abladiert abladiert NNP cord-015369-72cjogxz 872 1 und und NNP cord-015369-72cjogxz 873 1 ein ein NNP cord-015369-72cjogxz 873 2 Patient Patient NNP cord-015369-72cjogxz 873 3 unterzog unterzog NNP cord-015369-72cjogxz 873 4 sich sich NNP cord-015369-72cjogxz 873 5 einer einer NNP cord-015369-72cjogxz 873 6 linksseitigen linksseitigen NNP cord-015369-72cjogxz 874 1 Hemihepatektomie Hemihepatektomie NNP cord-015369-72cjogxz 874 2 nach nach NNP cord-015369-72cjogxz 874 3 rechtsseitiger rechtsseitiger XX cord-015369-72cjogxz 874 4 Ablation Ablation NNP cord-015369-72cjogxz 874 5 . . . cord-015369-72cjogxz 875 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 875 2 . . . cord-015369-72cjogxz 876 1 Das Das NNP cord-015369-72cjogxz 876 2 laparoskopische laparoskopische NN cord-015369-72cjogxz 876 3 Liver Liver NNP cord-015369-72cjogxz 876 4 Packing Packing NNP cord-015369-72cjogxz 876 5 ermöglicht ermöglicht NNP cord-015369-72cjogxz 876 6 eine eine NNP cord-015369-72cjogxz 876 7 ablative ablative JJ cord-015369-72cjogxz 876 8 Therapie Therapie NNP cord-015369-72cjogxz 876 9 der der NNP cord-015369-72cjogxz 876 10 Leber Leber NNP cord-015369-72cjogxz 876 11 in in IN cord-015369-72cjogxz 876 12 Patienten Patienten NNP cord-015369-72cjogxz 876 13 , , , cord-015369-72cjogxz 876 14 die die VBP cord-015369-72cjogxz 876 15 mit mit NNP cord-015369-72cjogxz 876 16 den den NNP cord-015369-72cjogxz 876 17 herkömmlichen herkömmlichen NNP cord-015369-72cjogxz 876 18 Möglichkeiten Möglichkeiten NNP cord-015369-72cjogxz 876 19 nicht nicht NNP cord-015369-72cjogxz 876 20 lokal lokal NNP cord-015369-72cjogxz 876 21 therapierbar therapierbar NN cord-015369-72cjogxz 876 22 sind sind NNP cord-015369-72cjogxz 876 23 . . . cord-015369-72cjogxz 877 1 Die die VB cord-015369-72cjogxz 877 2 Technik Technik NNP cord-015369-72cjogxz 877 3 ist ist NN cord-015369-72cjogxz 877 4 mittlerweile mittlerweile NNP cord-015369-72cjogxz 877 5 standartisiert standartisiert NNP cord-015369-72cjogxz 878 1 mit mit NNP cord-015369-72cjogxz 878 2 geringer geringer NNP cord-015369-72cjogxz 878 3 Mortalität Mortalität NNP cord-015369-72cjogxz 878 4 und und IN cord-015369-72cjogxz 878 5 Morbidität Morbidität NNP cord-015369-72cjogxz 878 6 durchführbar durchführbar NN cord-015369-72cjogxz 878 7 . . . cord-015369-72cjogxz 879 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 879 2 . . . cord-015369-72cjogxz 880 1 Ablationsverfahren Ablationsverfahren NNP cord-015369-72cjogxz 880 2 nehmen nehmen NNP cord-015369-72cjogxz 880 3 einen einen NNP cord-015369-72cjogxz 880 4 festen festen NNP cord-015369-72cjogxz 880 5 Platz Platz NNP cord-015369-72cjogxz 880 6 in in IN cord-015369-72cjogxz 880 7 der der NNP cord-015369-72cjogxz 880 8 Therapie Therapie NNP cord-015369-72cjogxz 880 9 von von NNP cord-015369-72cjogxz 880 10 Lebermetastasen Lebermetastasen NNP cord-015369-72cjogxz 880 11 ein ein NNP cord-015369-72cjogxz 880 12 . . . cord-015369-72cjogxz 881 1 Entscheidend Entscheidend NNP cord-015369-72cjogxz 881 2 fü fü IN cord-015369-72cjogxz 882 1 r r NNP cord-015369-72cjogxz 882 2 den den NNP cord-015369-72cjogxz 883 1 onkologischen onkologischen NNP cord-015369-72cjogxz 883 2 Erfolg Erfolg NNP cord-015369-72cjogxz 884 1 einer einer NNP cord-015369-72cjogxz 884 2 Ablation Ablation NNP cord-015369-72cjogxz 884 3 ist ist NN cord-015369-72cjogxz 884 4 die die VBP cord-015369-72cjogxz 884 5 Erzeugung Erzeugung NNP cord-015369-72cjogxz 884 6 einer einer NNP cord-015369-72cjogxz 884 7 ausreichend ausreichend NN cord-015369-72cjogxz 884 8 großen großen NNP cord-015369-72cjogxz 884 9 Thermoläsion Thermoläsion NNP cord-015369-72cjogxz 884 10 , , , cord-015369-72cjogxz 884 11 die die VB cord-015369-72cjogxz 884 12 die die VB cord-015369-72cjogxz 884 13 Metastase Metastase NNP cord-015369-72cjogxz 884 14 mit mit NNP cord-015369-72cjogxz 884 15 einem einem NNP cord-015369-72cjogxz 884 16 ausreichenden ausreichenden NNP cord-015369-72cjogxz 884 17 Sicherheitsabstand Sicherheitsabstand NNP cord-015369-72cjogxz 884 18 vollständig vollständig NNP cord-015369-72cjogxz 884 19 zerstört zerstört NNP cord-015369-72cjogxz 884 20 . . . cord-015369-72cjogxz 885 1 Ziel Ziel NNP cord-015369-72cjogxz 885 2 dieser dieser NNP cord-015369-72cjogxz 885 3 Studie Studie NNP cord-015369-72cjogxz 885 4 war war NN cord-015369-72cjogxz 885 5 es es NNP cord-015369-72cjogxz 885 6 , , , cord-015369-72cjogxz 885 7 bei bei NNP cord-015369-72cjogxz 885 8 Patienten Patienten NNP cord-015369-72cjogxz 885 9 die die VBP cord-015369-72cjogxz 885 10 aufgrund aufgrund NNP cord-015369-72cjogxz 885 11 von von NNP cord-015369-72cjogxz 885 12 kolorektalen kolorektalen NNP cord-015369-72cjogxz 885 13 Lebermetastasen Lebermetastasen NNP cord-015369-72cjogxz 885 14 eine eine NNP cord-015369-72cjogxz 885 15 ablative ablative JJ cord-015369-72cjogxz 885 16 Therapie Therapie NNP cord-015369-72cjogxz 885 17 erhielten erhielten NN cord-015369-72cjogxz 886 1 mögliche mögliche NNP cord-015369-72cjogxz 886 2 Faktoren Faktoren NNP cord-015369-72cjogxz 886 3 herauszuarbeiten herauszuarbeiten NNP cord-015369-72cjogxz 886 4 , , , cord-015369-72cjogxz 886 5 die die VB cord-015369-72cjogxz 886 6 eine eine JJ cord-015369-72cjogxz 886 7 unvollständige unvollständige NNP cord-015369-72cjogxz 886 8 Thermoablation Thermoablation NNP cord-015369-72cjogxz 886 9 verursachen verursachen NN cord-015369-72cjogxz 886 10 . . . cord-015369-72cjogxz 887 1 Methodik Methodik NNP cord-015369-72cjogxz 887 2 . . . cord-015369-72cjogxz 888 1 Patienten Patienten NNP cord-015369-72cjogxz 888 2 mit mit VBP cord-015369-72cjogxz 888 3 irresektablen irresektablen NNP cord-015369-72cjogxz 888 4 kolorektalen kolorektalen IN cord-015369-72cjogxz 888 5 Lebermetastasen Lebermetastasen NNP cord-015369-72cjogxz 888 6 . . . cord-015369-72cjogxz 889 1 Ab Ab NNP cord-015369-72cjogxz 889 2 1996 1996 CD cord-015369-72cjogxz 889 3 erhielten erhielten NNS cord-015369-72cjogxz 889 4 die die VBP cord-015369-72cjogxz 890 1 Patienten Patienten NNP cord-015369-72cjogxz 890 2 eine eine NNP cord-015369-72cjogxz 890 3 laserinduzierte laserinduzierte NNP cord-015369-72cjogxz 890 4 Thermotherapie Thermotherapie NNP cord-015369-72cjogxz 890 5 ( ( -LRB- cord-015369-72cjogxz 890 6 LITT LITT NNP cord-015369-72cjogxz 890 7 ) ) -RRB- cord-015369-72cjogxz 891 1 , , , cord-015369-72cjogxz 891 2 ab ab NNP cord-015369-72cjogxz 891 3 2003 2003 CD cord-015369-72cjogxz 892 1 eine eine NNP cord-015369-72cjogxz 892 2 bipolare bipolare NNP cord-015369-72cjogxz 892 3 Radiofrequenzablation Radiofrequenzablation NNP cord-015369-72cjogxz 892 4 ( ( -LRB- cord-015369-72cjogxz 892 5 RFA RFA NNP cord-015369-72cjogxz 892 6 ) ) -RRB- cord-015369-72cjogxz 892 7 . . . cord-015369-72cjogxz 893 1 Ausschlußkriterien Ausschlußkriterien NNP cord-015369-72cjogxz 893 2 : : : cord-015369-72cjogxz 894 1 Metastasenanzahl Metastasenanzahl NNS cord-015369-72cjogxz 894 2 > > XX cord-015369-72cjogxz 894 3 5 5 CD cord-015369-72cjogxz 894 4 , , , cord-015369-72cjogxz 894 5 Metastasendurchmesser Metastasendurchmesser NNP cord-015369-72cjogxz 894 6 > > XX cord-015369-72cjogxz 894 7 5 5 CD cord-015369-72cjogxz 894 8 cm cm NNS cord-015369-72cjogxz 894 9 , , , cord-015369-72cjogxz 894 10 extrahepatische extrahepatische NNP cord-015369-72cjogxz 894 11 Tumormanifestation Tumormanifestation NNP cord-015369-72cjogxz 894 12 . . . cord-015369-72cjogxz 895 1 Bei Bei NNP cord-015369-72cjogxz 895 2 den den NNP cord-015369-72cjogxz 896 1 offen offen NNP cord-015369-72cjogxz 896 2 - - HYPH cord-015369-72cjogxz 896 3 chirurgischen chirurgischen NNP cord-015369-72cjogxz 896 4 Ablationen Ablationen NNP cord-015369-72cjogxz 896 5 erfolgte erfolgte NNP cord-015369-72cjogxz 896 6 eine eine NNP cord-015369-72cjogxz 896 7 sonografische sonografische NNP cord-015369-72cjogxz 896 8 Punktionskontrolle Punktionskontrolle NNP cord-015369-72cjogxz 896 9 , , , cord-015369-72cjogxz 896 10 die die VBP cord-015369-72cjogxz 896 11 perkutanen perkutanen NNP cord-015369-72cjogxz 896 12 Ablationen Ablationen NNP cord-015369-72cjogxz 896 13 erfolgte erfolgte NN cord-015369-72cjogxz 896 14 CT CT NNP cord-015369-72cjogxz 896 15 - - HYPH cord-015369-72cjogxz 896 16 oder oder NNP cord-015369-72cjogxz 896 17 sonografiegestützt sonografiegestützt VBN cord-015369-72cjogxz 896 18 in in IN cord-015369-72cjogxz 896 19 Lokalanästhesie Lokalanästhesie NNP cord-015369-72cjogxz 896 20 . . . cord-015369-72cjogxz 897 1 Zur Zur NNP cord-015369-72cjogxz 897 2 Kontrolle Kontrolle NNP cord-015369-72cjogxz 897 3 der der NN cord-015369-72cjogxz 897 4 vollständigen vollständigen NNP cord-015369-72cjogxz 897 5 Ablation ablation NN cord-015369-72cjogxz 898 1 ( ( -LRB- cord-015369-72cjogxz 898 2 , , , cord-015369-72cjogxz 898 3 , , , cord-015369-72cjogxz 898 4 R0 R0 NNP cord-015369-72cjogxz 898 5 ' ' POS cord-015369-72cjogxz 898 6 ' ' '' cord-015369-72cjogxz 898 7 ) ) -RRB- cord-015369-72cjogxz 899 1 erhielten erhielten NNP cord-015369-72cjogxz 899 2 alle alle NNP cord-015369-72cjogxz 900 1 Patienten Patienten NNP cord-015369-72cjogxz 900 2 24 24 CD cord-015369-72cjogxz 900 3 - - SYM cord-015369-72cjogxz 900 4 48 48 CD cord-015369-72cjogxz 901 1 h h NNP cord-015369-72cjogxz 901 2 postinterventionell postinterventionell NNP cord-015369-72cjogxz 901 3 eine eine NNP cord-015369-72cjogxz 901 4 KM KM NNP cord-015369-72cjogxz 901 5 - - HYPH cord-015369-72cjogxz 901 6 gestützte gestützte NNP cord-015369-72cjogxz 901 7 MRT MRT NNP cord-015369-72cjogxz 901 8 . . . cord-015369-72cjogxz 902 1 In in IN cord-015369-72cjogxz 902 2 Abhängigkeit Abhängigkeit NNP cord-015369-72cjogxz 902 3 der der NN cord-015369-72cjogxz 902 4 erreichten erreichten NNP cord-015369-72cjogxz 902 5 , , , cord-015369-72cjogxz 902 6 , , , cord-015369-72cjogxz 902 7 R0-Ablation r0-ablation NN cord-015369-72cjogxz 902 8 ' ' '' cord-015369-72cjogxz 902 9 ' ' `` cord-015369-72cjogxz 902 10 erfolgte erfolgte NN cord-015369-72cjogxz 902 11 die die VBP cord-015369-72cjogxz 902 12 Einteilung Einteilung NNP cord-015369-72cjogxz 902 13 der der NNP cord-015369-72cjogxz 902 14 Patienten Patienten NNP cord-015369-72cjogxz 902 15 in in IN cord-015369-72cjogxz 902 16 zwei zwei CD cord-015369-72cjogxz 902 17 Gruppen Gruppen NNP cord-015369-72cjogxz 902 18 : : : cord-015369-72cjogxz 903 1 Gruppe Gruppe NNP cord-015369-72cjogxz 903 2 I -PRON- PRP cord-015369-72cjogxz 903 3 : : : cord-015369-72cjogxz 903 4 , , , cord-015369-72cjogxz 903 5 , , , cord-015369-72cjogxz 903 6 R0-Ablation r0-ablation NN cord-015369-72cjogxz 903 7 ' ' '' cord-015369-72cjogxz 903 8 ' ' '' cord-015369-72cjogxz 903 9 , , , cord-015369-72cjogxz 903 10 Gruppe Gruppe NNP cord-015369-72cjogxz 903 11 II II NNP cord-015369-72cjogxz 903 12 : : : cord-015369-72cjogxz 903 13 keine keine NNP cord-015369-72cjogxz 903 14 , , , cord-015369-72cjogxz 903 15 , , , cord-015369-72cjogxz 903 16 R0-Ablation r0-ablation NN cord-015369-72cjogxz 903 17 ' ' '' cord-015369-72cjogxz 903 18 ' ' '' cord-015369-72cjogxz 903 19 . . . cord-015369-72cjogxz 904 1 , , , cord-015369-72cjogxz 904 2 , , , cord-015369-72cjogxz 904 3 R0-Ablation r0-ablation NN cord-015369-72cjogxz 904 4 ' ' '' cord-015369-72cjogxz 904 5 ' ' '' cord-015369-72cjogxz 904 6 ¼ ¼ NNP cord-015369-72cjogxz 904 7 Sicherheitsabstand Sicherheitsabstand NNP cord-015369-72cjogxz 904 8 von von NNP cord-015369-72cjogxz 904 9 allseits allseit VBZ cord-015369-72cjogxz 904 10 1 1 CD cord-015369-72cjogxz 904 11 cm cm NNP cord-015369-72cjogxz 904 12 in in IN cord-015369-72cjogxz 904 13 der der NN cord-015369-72cjogxz 904 14 postinterventionellen postinterventionellen JJ cord-015369-72cjogxz 904 15 MR MR NNP cord-015369-72cjogxz 904 16 - - HYPH cord-015369-72cjogxz 904 17 Untersuchung Untersuchung NNP cord-015369-72cjogxz 904 18 . . . cord-015369-72cjogxz 905 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 905 2 Grundlagen Grundlagen NNP cord-015369-72cjogxz 905 3 . . . cord-015369-72cjogxz 906 1 Die die VB cord-015369-72cjogxz 906 2 chirurgische chirurgische NN cord-015369-72cjogxz 906 3 Versorgung Versorgung NNP cord-015369-72cjogxz 906 4 der der NNP cord-015369-72cjogxz 906 5 Leistenhernie Leistenhernie NNP cord-015369-72cjogxz 906 6 galt galt NNP cord-015369-72cjogxz 906 7 lange lange NNP cord-015369-72cjogxz 906 8 Zeit Zeit NNP cord-015369-72cjogxz 906 9 als als NN cord-015369-72cjogxz 906 10 wenig wenig NNP cord-015369-72cjogxz 906 11 interessanter interessanter NNP cord-015369-72cjogxz 906 12 Standardeingriff Standardeingriff NNP cord-015369-72cjogxz 906 13 und und XX cord-015369-72cjogxz 907 1 wurde wurde NNP cord-015369-72cjogxz 907 2 nicht nicht NNP cord-015369-72cjogxz 907 3 selten selten NNP cord-015369-72cjogxz 907 4 dem dem NNP cord-015369-72cjogxz 907 5 jungen jungen NNP cord-015369-72cjogxz 907 6 Ausbildungsassistenten Ausbildungsassistenten NNP cord-015369-72cjogxz 907 7 überlassen überlassen NN cord-015369-72cjogxz 907 8 . . . cord-015369-72cjogxz 908 1 In in IN cord-015369-72cjogxz 908 2 den den NNP cord-015369-72cjogxz 908 3 letzten letzten NNP cord-015369-72cjogxz 908 4 Jahren Jahren NNP cord-015369-72cjogxz 908 5 hat hat NN cord-015369-72cjogxz 908 6 sowohl sowohl NN cord-015369-72cjogxz 908 7 die die VBP cord-015369-72cjogxz 908 8 wissenschaftliche wissenschaftliche NNP cord-015369-72cjogxz 908 9 Auseinandersetzung Auseinandersetzung NNP cord-015369-72cjogxz 908 10 als als NNP cord-015369-72cjogxz 908 11 auch auch NNP cord-015369-72cjogxz 908 12 das das NNP cord-015369-72cjogxz 908 13 Interesse Interesse NNP cord-015369-72cjogxz 909 1 an an DT cord-015369-72cjogxz 909 2 ergebnisorientierter ergebnisorientierter NN cord-015369-72cjogxz 909 3 Qualitätssicherung Qualitätssicherung NNP cord-015369-72cjogxz 909 4 deutlich deutlich NNP cord-015369-72cjogxz 909 5 zugenommen zugenommen NNP cord-015369-72cjogxz 909 6 . . . cord-015369-72cjogxz 910 1 Methodik Methodik NNP cord-015369-72cjogxz 910 2 . . . cord-015369-72cjogxz 911 1 In in IN cord-015369-72cjogxz 911 2 Zusammenarbeit Zusammenarbeit NNP cord-015369-72cjogxz 911 3 mit mit NN cord-015369-72cjogxz 911 4 dem dem NNP cord-015369-72cjogxz 911 5 Zürser Zürser NNP cord-015369-72cjogxz 911 6 Hernienforum Hernienforum NNP cord-015369-72cjogxz 911 7 wurde wurde NNP cord-015369-72cjogxz 911 8 an an DT cord-015369-72cjogxz 911 9 unserer unserer JJ cord-015369-72cjogxz 911 10 Abteilung Abteilung NNP cord-015369-72cjogxz 911 11 ein ein NNP cord-015369-72cjogxz 911 12 Herniendokumentationssystem Herniendokumentationssystem NNP cord-015369-72cjogxz 911 13 entwickelt entwickelt NNP cord-015369-72cjogxz 911 14 . . . cord-015369-72cjogxz 912 1 Als Als NNP cord-015369-72cjogxz 912 2 Basis Basis NNP cord-015369-72cjogxz 912 3 diente diente NNP cord-015369-72cjogxz 912 4 ein ein NNP cord-015369-72cjogxz 912 5 Software Software NNP cord-015369-72cjogxz 912 6 - - HYPH cord-015369-72cjogxz 912 7 Programm Programm NNP cord-015369-72cjogxz 913 1 , , , cord-015369-72cjogxz 913 2 das das NNP cord-015369-72cjogxz 913 3 für für NNP cord-015369-72cjogxz 913 4 die die VBP cord-015369-72cjogxz 913 5 Qualitätssicherungsstudie Qualitätssicherungsstudie NNP cord-015369-72cjogxz 913 6 des des FW cord-015369-72cjogxz 913 7 BÖ BÖ NNP cord-015369-72cjogxz 913 8 C C NNP cord-015369-72cjogxz 913 9 i -PRON- PRP cord-015369-72cjogxz 913 10 m be VBP cord-015369-72cjogxz 913 11 Jahr Jahr NNP cord-015369-72cjogxz 913 12 2000 2000 CD cord-015369-72cjogxz 913 13 geschrieben geschrieben NNP cord-015369-72cjogxz 913 14 wurde wurde NNP cord-015369-72cjogxz 913 15 . . . cord-015369-72cjogxz 914 1 Dieses Dieses NNP cord-015369-72cjogxz 914 2 wurde wurde NN cord-015369-72cjogxz 915 1 i i PRP cord-015369-72cjogxz 916 1 m m NNP cord-015369-72cjogxz 916 2 Expertengremium Expertengremium NNP cord-015369-72cjogxz 916 3 auf auf NNP cord-015369-72cjogxz 916 4 heutige heutige NN cord-015369-72cjogxz 916 5 Anforderungen Anforderungen NNP cord-015369-72cjogxz 916 6 adaptiert adaptiert NNP cord-015369-72cjogxz 917 1 und und NNP cord-015369-72cjogxz 917 2 von von NNP cord-015369-72cjogxz 917 3 der der NNP cord-015369-72cjogxz 917 4 hausinternen hausinternen NNP cord-015369-72cjogxz 917 5 IT IT NNP cord-015369-72cjogxz 917 6 in in IN cord-015369-72cjogxz 917 7 das das NNP cord-015369-72cjogxz 917 8 Krankenhaussystem Krankenhaussystem NNP cord-015369-72cjogxz 917 9 SAP SAP NNP cord-015369-72cjogxz 917 10 integriert integriert NNP cord-015369-72cjogxz 917 11 . . . cord-015369-72cjogxz 918 1 Die die VB cord-015369-72cjogxz 918 2 eingegeben eingegeben NNP cord-015369-72cjogxz 918 3 Daten Daten NNP cord-015369-72cjogxz 918 4 können können XX cord-015369-72cjogxz 919 1 über über NNP cord-015369-72cjogxz 920 1 eine eine NNP cord-015369-72cjogxz 920 2 ACCESS ACCESS NNP cord-015369-72cjogxz 920 3 - - HYPH cord-015369-72cjogxz 920 4 Datenbank Datenbank NNP cord-015369-72cjogxz 920 5 analysiert analysiert NN cord-015369-72cjogxz 920 6 und und NNP cord-015369-72cjogxz 920 7 ausgewertet ausgewertet NNP cord-015369-72cjogxz 920 8 werden werden NNP cord-015369-72cjogxz 920 9 . . . cord-015369-72cjogxz 921 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 921 2 . . . cord-015369-72cjogxz 922 1 Das Das NNP cord-015369-72cjogxz 922 2 System System NNP cord-015369-72cjogxz 922 3 ist ist NNP cord-015369-72cjogxz 922 4 an an DT cord-015369-72cjogxz 922 5 unserer unserer JJ cord-015369-72cjogxz 922 6 Abteilung Abteilung NNP cord-015369-72cjogxz 922 7 seit seit NNP cord-015369-72cjogxz 922 8 1.1.2007 1.1.2007 CD cord-015369-72cjogxz 922 9 in in IN cord-015369-72cjogxz 922 10 Betrieb Betrieb NNP cord-015369-72cjogxz 922 11 . . . cord-015369-72cjogxz 923 1 Die die VB cord-015369-72cjogxz 923 2 Dateneingabe Dateneingabe NNP cord-015369-72cjogxz 923 3 erfolgt erfolgt NN cord-015369-72cjogxz 923 4 zu zu XX cord-015369-72cjogxz 924 1 3 3 LS cord-015369-72cjogxz 924 2 Zeitpunkten Zeitpunkten NNP cord-015369-72cjogxz 924 3 ( ( -LRB- cord-015369-72cjogxz 924 4 i -PRON- PRP cord-015369-72cjogxz 924 5 m be VBP cord-015369-72cjogxz 924 6 OP OP NNP cord-015369-72cjogxz 924 7 , , , cord-015369-72cjogxz 924 8 nach nach NNP cord-015369-72cjogxz 924 9 Entlassung Entlassung NNP cord-015369-72cjogxz 924 10 , , , cord-015369-72cjogxz 924 11 bei bei NNP cord-015369-72cjogxz 924 12 Follow Follow NNP cord-015369-72cjogxz 924 13 - - HYPH cord-015369-72cjogxz 924 14 up up NN cord-015369-72cjogxz 924 15 Kontrolle Kontrolle NNP cord-015369-72cjogxz 924 16 ) ) -RRB- cord-015369-72cjogxz 925 1 und und NNP cord-015369-72cjogxz 926 1 ist ist NNP cord-015369-72cjogxz 926 2 an an DT cord-015369-72cjogxz 926 3 einer einer NNP cord-015369-72cjogxz 926 4 Abteilung Abteilung NNP cord-015369-72cjogxz 926 5 eines eine NNS cord-015369-72cjogxz 927 1 Ordenskrankenhauses Ordenskrankenhauses NNP cord-015369-72cjogxz 927 2 mit mit VBP cord-015369-72cjogxz 927 3 limitierter limitierter NNP cord-015369-72cjogxz 927 4 Mitarbeiter Mitarbeiter NNP cord-015369-72cjogxz 927 5 - - HYPH cord-015369-72cjogxz 927 6 Zahl Zahl NNP cord-015369-72cjogxz 927 7 gut gut NN cord-015369-72cjogxz 927 8 zu zu NNP cord-015369-72cjogxz 927 9 bewerkstelligen bewerkstelligen NNP cord-015369-72cjogxz 927 10 . . . cord-015369-72cjogxz 928 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 928 2 . . . cord-015369-72cjogxz 929 1 Nach Nach NNP cord-015369-72cjogxz 929 2 erfolgreichem erfolgreichem NNP cord-015369-72cjogxz 930 1 Testbetrieb Testbetrieb NNP cord-015369-72cjogxz 930 2 kann kann NNP cord-015369-72cjogxz 931 1 das das NNP cord-015369-72cjogxz 931 2 Herniendokumentationssystem Herniendokumentationssystem NNP cord-015369-72cjogxz 931 3 anderen anderen NNP cord-015369-72cjogxz 932 1 interessierten interessierten NNP cord-015369-72cjogxz 933 1 Abteilungen Abteilungen NNP cord-015369-72cjogxz 933 2 zur zur NNP cord-015369-72cjogxz 933 3 Verfügung Verfügung NNP cord-015369-72cjogxz 934 1 gestellt gestellt NNP cord-015369-72cjogxz 934 2 werden werden NNP cord-015369-72cjogxz 934 3 . . . cord-015369-72cjogxz 935 1 Die die VB cord-015369-72cjogxz 935 2 Anwendungsmöglichkeiten Anwendungsmöglichkeiten NNP cord-015369-72cjogxz 935 3 reichen reichen NNP cord-015369-72cjogxz 935 4 von von NNP cord-015369-72cjogxz 935 5 der der NNP cord-015369-72cjogxz 935 6 eigenen eigenen NNP cord-015369-72cjogxz 936 1 Qualitätskontrolle Qualitätskontrolle NNP cord-015369-72cjogxz 936 2 bis bis NNP cord-015369-72cjogxz 936 3 zur zur NNP cord-015369-72cjogxz 936 4 häuserübergreifenden häuserübergreifenden NNP cord-015369-72cjogxz 937 1 Analyse Analyse NNP cord-015369-72cjogxz 937 2 neuer neuer VB cord-015369-72cjogxz 937 3 medizinischer medizinischer NNP cord-015369-72cjogxz 938 1 Produkte Produkte NNP cord-015369-72cjogxz 938 2 oder oder NNP cord-015369-72cjogxz 938 3 OP OP NNP cord-015369-72cjogxz 938 4 - - HYPH cord-015369-72cjogxz 938 5 Methoden Methoden NNP cord-015369-72cjogxz 938 6 . . . cord-015369-72cjogxz 939 1 Laparoscopic laparoscopic JJ cord-015369-72cjogxz 939 2 ventral ventral JJ cord-015369-72cjogxz 939 3 hernia hernia NN cord-015369-72cjogxz 939 4 repair repair NN cord-015369-72cjogxz 939 5 with with IN cord-015369-72cjogxz 939 6 IPOMexperience ipomexperience NN cord-015369-72cjogxz 939 7 from from IN cord-015369-72cjogxz 939 8 the the DT cord-015369-72cjogxz 939 9 first first JJ cord-015369-72cjogxz 939 10 100 100 CD cord-015369-72cjogxz 939 11 cases case NNS cord-015369-72cjogxz 940 1 Abteilung Abteilung NNP cord-015369-72cjogxz 940 2 für für IN cord-015369-72cjogxz 940 3 Chirurgie Chirurgie NNP cord-015369-72cjogxz 940 4 , , , cord-015369-72cjogxz 940 5 Bruck Bruck NNP cord-015369-72cjogxz 940 6 / / SYM cord-015369-72cjogxz 940 7 Mur Mur NNP cord-015369-72cjogxz 940 8 , , , cord-015369-72cjogxz 940 9 Austria Austria NNP cord-015369-72cjogxz 940 10 Grundlagen Grundlagen NNP cord-015369-72cjogxz 940 11 . . . cord-015369-72cjogxz 941 1 Bereits Bereits NNP cord-015369-72cjogxz 941 2 1993 1993 CD cord-015369-72cjogxz 942 1 wurde wurde NNP cord-015369-72cjogxz 942 2 von von NNP cord-015369-72cjogxz 942 3 K. K. NNP cord-015369-72cjogxz 942 4 LeBlanc LeBlanc NNP cord-015369-72cjogxz 942 5 erstmals erstmal VBZ cord-015369-72cjogxz 943 1 ü ü NN cord-015369-72cjogxz 944 1 ber ber NNP cord-015369-72cjogxz 944 2 den den NNP cord-015369-72cjogxz 944 3 Verschluss Verschluss NNP cord-015369-72cjogxz 944 4 einer einer NNP cord-015369-72cjogxz 944 5 Bauchwandhernie Bauchwandhernie NNP cord-015369-72cjogxz 944 6 in in IN cord-015369-72cjogxz 944 7 laparoskopischer laparoskopischer JJ cord-015369-72cjogxz 944 8 IPOM IPOM NNP cord-015369-72cjogxz 945 1 ( ( -LRB- cord-015369-72cjogxz 945 2 intraperitoneales intraperitoneales NNP cord-015369-72cjogxz 945 3 onlay onlay NN cord-015369-72cjogxz 945 4 mesh)-Technik mesh)-Technik VBZ cord-015369-72cjogxz 945 5 berichtet berichtet NNP cord-015369-72cjogxz 945 6 . . . cord-015369-72cjogxz 946 1 Erst Erst NNP cord-015369-72cjogxz 946 2 mit mit NNP cord-015369-72cjogxz 946 3 der der NNP cord-015369-72cjogxz 946 4 Entwicklung Entwicklung NNP cord-015369-72cjogxz 946 5 verschiedener verschiedener NNP cord-015369-72cjogxz 946 6 Kunststoffnetze Kunststoffnetze NNP cord-015369-72cjogxz 946 7 , , , cord-015369-72cjogxz 946 8 die die VB cord-015369-72cjogxz 946 9 immer immer NNP cord-015369-72cjogxz 946 10 besser besser NNP cord-015369-72cjogxz 946 11 die die NNP cord-015369-72cjogxz 946 12 speziellen speziellen NNP cord-015369-72cjogxz 947 1 Anforderungen Anforderungen NNP cord-015369-72cjogxz 948 1 fü fü IN cord-015369-72cjogxz 948 2 r r NNP cord-015369-72cjogxz 948 3 eine eine NNP cord-015369-72cjogxz 949 1 intraabdominelle intraabdominelle NNP cord-015369-72cjogxz 949 2 Platzierung Platzierung NNP cord-015369-72cjogxz 949 3 erfü erfü NN cord-015369-72cjogxz 949 4 llen llen NNP cord-015369-72cjogxz 949 5 , , , cord-015369-72cjogxz 950 1 kam kam NNP cord-015369-72cjogxz 950 2 es es XX cord-015369-72cjogxz 950 3 zu zu NNP cord-015369-72cjogxz 950 4 einer einer NNP cord-015369-72cjogxz 951 1 zunehmenden zunehmenden NNP cord-015369-72cjogxz 951 2 Verbreitung Verbreitung NNP cord-015369-72cjogxz 951 3 dieser dieser NNP cord-015369-72cjogxz 951 4 Technik Technik NNP cord-015369-72cjogxz 951 5 . . . cord-015369-72cjogxz 952 1 Es Es NNP cord-015369-72cjogxz 952 2 wird wird NNP cord-015369-72cjogxz 952 3 ü ü NN cord-015369-72cjogxz 953 1 ber ber NNP cord-015369-72cjogxz 953 2 unsere unsere NNP cord-015369-72cjogxz 953 3 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 953 4 aus aus NNP cord-015369-72cjogxz 953 5 den den NNP cord-015369-72cjogxz 953 6 ersten ersten NNP cord-015369-72cjogxz 953 7 100 100 CD cord-015369-72cjogxz 953 8 Fällen Fällen NNP cord-015369-72cjogxz 953 9 berichtet berichtet NNP cord-015369-72cjogxz 953 10 , , , cord-015369-72cjogxz 953 11 wobei wobei NNP cord-015369-72cjogxz 953 12 das das NNP cord-015369-72cjogxz 953 13 besondere besondere NNP cord-015369-72cjogxz 953 14 Augenmerk Augenmerk NNP cord-015369-72cjogxz 953 15 den den NNP cord-015369-72cjogxz 953 16 Rezidiven Rezidiven NNP cord-015369-72cjogxz 953 17 und und XX cord-015369-72cjogxz 954 1 ihren ihren NNP cord-015369-72cjogxz 954 2 möglichen möglichen NNP cord-015369-72cjogxz 954 3 Ursachen Ursachen NNP cord-015369-72cjogxz 954 4 gilt gilt NN cord-015369-72cjogxz 954 5 . . . cord-015369-72cjogxz 955 1 Methodik Methodik NNP cord-015369-72cjogxz 955 2 . . . cord-015369-72cjogxz 956 1 Verwendet Verwendet NNP cord-015369-72cjogxz 956 2 wurde wurde VBD cord-015369-72cjogxz 956 3 in in IN cord-015369-72cjogxz 956 4 allen allen NNP cord-015369-72cjogxz 956 5 Fällen Fällen NNP cord-015369-72cjogxz 956 6 ein ein VBP cord-015369-72cjogxz 956 7 dreidimensionales dreidimensionale NNS cord-015369-72cjogxz 956 8 , , , cord-015369-72cjogxz 956 9 multifaser multifaser NNP cord-015369-72cjogxz 956 10 Polyestermesh Polyestermesh NNP cord-015369-72cjogxz 956 11 mit mit NNP cord-015369-72cjogxz 956 12 resorbierbarer resorbierbarer NNP cord-015369-72cjogxz 956 13 Beschichtung Beschichtung NNP cord-015369-72cjogxz 956 14 . . . cord-015369-72cjogxz 957 1 Die die UH cord-015369-72cjogxz 957 2 Eingriffe Eingriffe NNP cord-015369-72cjogxz 957 3 wurden wurden VBN cord-015369-72cjogxz 958 1 von von NNP cord-015369-72cjogxz 958 2 2 2 CD cord-015369-72cjogxz 958 3 Operateuren Operateuren NNP cord-015369-72cjogxz 958 4 durchgefü durchgefü NN cord-015369-72cjogxz 958 5 hrt hrt NNP cord-015369-72cjogxz 958 6 . . . cord-015369-72cjogxz 959 1 Je Je NNP cord-015369-72cjogxz 959 2 nach nach NNP cord-015369-72cjogxz 959 3 Operateur Operateur NNP cord-015369-72cjogxz 959 4 erfolgte erfolgte NN cord-015369-72cjogxz 959 5 die die VBP cord-015369-72cjogxz 959 6 Befestigung Befestigung NNP cord-015369-72cjogxz 959 7 entweder entweder NN cord-015369-72cjogxz 959 8 mit mit NNP cord-015369-72cjogxz 959 9 Spiraltacks Spiraltacks NNP cord-015369-72cjogxz 959 10 oder oder NN cord-015369-72cjogxz 959 11 einer einer NNP cord-015369-72cjogxz 959 12 Kombination Kombination NNP cord-015369-72cjogxz 959 13 aus aus NNP cord-015369-72cjogxz 959 14 Spiraltacks Spiraltacks NNP cord-015369-72cjogxz 959 15 und und IN cord-015369-72cjogxz 959 16 transfaszialen transfaszialen NNP cord-015369-72cjogxz 959 17 Nähten Nähten NNP cord-015369-72cjogxz 959 18 . . . cord-015369-72cjogxz 960 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 960 2 . . . cord-015369-72cjogxz 961 1 Unsere Unsere NNP cord-015369-72cjogxz 961 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 961 3 bestätigen bestätigen NNP cord-015369-72cjogxz 961 4 , , , cord-015369-72cjogxz 961 5 dass dass NNP cord-015369-72cjogxz 961 6 in in IN cord-015369-72cjogxz 961 7 erster erster NNP cord-015369-72cjogxz 961 8 Linie Linie NNP cord-015369-72cjogxz 961 9 eine eine NNP cord-015369-72cjogxz 961 10 ausreichende ausreichende NNP cord-015369-72cjogxz 961 11 Ü Ü NNP cord-015369-72cjogxz 961 12 berlappung berlappung NNP cord-015369-72cjogxz 961 13 der der NNP cord-015369-72cjogxz 961 14 Bruchlücke Bruchlücke NNP cord-015369-72cjogxz 961 15 das das NNP cord-015369-72cjogxz 961 16 Rezidivrisiko Rezidivrisiko NNP cord-015369-72cjogxz 961 17 niedrig niedrig NN cord-015369-72cjogxz 961 18 hält hält NNP cord-015369-72cjogxz 961 19 . . . cord-015369-72cjogxz 962 1 Dies die NNS cord-015369-72cjogxz 963 1 ist ist NNP cord-015369-72cjogxz 963 2 ein ein NNP cord-015369-72cjogxz 963 3 Grund Grund NNP cord-015369-72cjogxz 963 4 warum warum NNP cord-015369-72cjogxz 963 5 die die VB cord-015369-72cjogxz 963 6 laparoskopische laparoskopische NNP cord-015369-72cjogxz 963 7 Technik Technik NNP cord-015369-72cjogxz 963 8 derzeit derzeit NNP cord-015369-72cjogxz 963 9 hinsichtlich hinsichtlich NNP cord-015369-72cjogxz 964 1 Bruchlückengröße Bruchlückengröße NNP cord-015369-72cjogxz 964 2 und und IN cord-015369-72cjogxz 964 3 Lokalisation Lokalisation NNP cord-015369-72cjogxz 964 4 der der NNP cord-015369-72cjogxz 964 5 Hernie Hernie NNP cord-015369-72cjogxz 964 6 noch noch NNP cord-015369-72cjogxz 964 7 Grenzen Grenzen NNP cord-015369-72cjogxz 964 8 aufweist aufweist NN cord-015369-72cjogxz 964 9 . . . cord-015369-72cjogxz 965 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 965 2 . . . cord-015369-72cjogxz 966 1 Unsere Unsere NNP cord-015369-72cjogxz 966 2 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 966 3 mit mit NNP cord-015369-72cjogxz 966 4 den den NNP cord-015369-72cjogxz 966 5 ersten ersten NNP cord-015369-72cjogxz 967 1 100 100 CD cord-015369-72cjogxz 967 2 durchgefü durchgefü NNP cord-015369-72cjogxz 967 3 hrten hrten NNP cord-015369-72cjogxz 967 4 Operationen Operationen NNP cord-015369-72cjogxz 967 5 zeigen zeigen NNP cord-015369-72cjogxz 967 6 , , , cord-015369-72cjogxz 967 7 dass dass NNP cord-015369-72cjogxz 967 8 mit mit NNP cord-015369-72cjogxz 967 9 ausreichender ausreichender NNP cord-015369-72cjogxz 968 1 minimal minimal JJ cord-015369-72cjogxz 968 2 invasiver invasiver NNP cord-015369-72cjogxz 969 1 Erfahrung Erfahrung NNP cord-015369-72cjogxz 969 2 und und IN cord-015369-72cjogxz 969 3 entsprechender entsprechender NNPS cord-015369-72cjogxz 969 4 Patientenselektion Patientenselektion NNP cord-015369-72cjogxz 969 5 die die VBP cord-015369-72cjogxz 969 6 laparoskopische laparoskopische NN cord-015369-72cjogxz 970 1 IPOM IPOM NNP cord-015369-72cjogxz 970 2 - - HYPH cord-015369-72cjogxz 970 3 Technik Technik NNP cord-015369-72cjogxz 970 4 einen einen NNP cord-015369-72cjogxz 970 5 wichtigen wichtigen NNP cord-015369-72cjogxz 970 6 Platz Platz NNP cord-015369-72cjogxz 970 7 in in IN cord-015369-72cjogxz 970 8 der der NNP cord-015369-72cjogxz 970 9 optimalen optimalen NNP cord-015369-72cjogxz 971 1 Versorgung Versorgung NNP cord-015369-72cjogxz 971 2 von von NNP cord-015369-72cjogxz 971 3 Bauchwandhernien Bauchwandhernien NNP cord-015369-72cjogxz 971 4 einnehmen einnehmen NN cord-015369-72cjogxz 971 5 kann kann NNP cord-015369-72cjogxz 971 6 . . . cord-015369-72cjogxz 972 1 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 972 2 mit mit NNP cord-015369-72cjogxz 972 3 118 118 CD cord-015369-72cjogxz 972 4 konsekutiven konsekutiven NNP cord-015369-72cjogxz 972 5 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 972 6 Narbenhernienoperationen Narbenhernienoperationen NNP cord-015369-72cjogxz 972 7 Grundlagen Grundlagen NNP cord-015369-72cjogxz 972 8 . . . cord-015369-72cjogxz 973 1 Die die VB cord-015369-72cjogxz 973 2 Reparation reparation NN cord-015369-72cjogxz 973 3 von von NNP cord-015369-72cjogxz 973 4 Narbenhernien Narbenhernien NNP cord-015369-72cjogxz 973 5 stellt stellt NNP cord-015369-72cjogxz 973 6 einen einen NNP cord-015369-72cjogxz 973 7 der der NNP cord-015369-72cjogxz 973 8 häufigsten häufigsten NNP cord-015369-72cjogxz 973 9 Eingriffe Eingriffe NNP cord-015369-72cjogxz 973 10 dar dar NNP cord-015369-72cjogxz 973 11 . . . cord-015369-72cjogxz 974 1 In in IN cord-015369-72cjogxz 974 2 letzter letzter NN cord-015369-72cjogxz 974 3 Zeit Zeit NNP cord-015369-72cjogxz 974 4 kommt kommt NNP cord-015369-72cjogxz 974 5 die die NNP cord-015369-72cjogxz 974 6 laparoskopische laparoskopische NNP cord-015369-72cjogxz 974 7 intraperitoneale intraperitoneale NNP cord-015369-72cjogxz 974 8 onlay onlay NN cord-015369-72cjogxz 974 9 mesh mesh NN cord-015369-72cjogxz 974 10 Technik Technik NNP cord-015369-72cjogxz 974 11 ( ( -LRB- cord-015369-72cjogxz 974 12 lap lap NN cord-015369-72cjogxz 974 13 . . . cord-015369-72cjogxz 975 1 IPOM IPOM NNP cord-015369-72cjogxz 975 2 ) ) -RRB- cord-015369-72cjogxz 975 3 vermehrt vermehrt NN cord-015369-72cjogxz 975 4 zum zum NNP cord-015369-72cjogxz 975 5 Einsatz Einsatz NNP cord-015369-72cjogxz 975 6 . . . cord-015369-72cjogxz 976 1 Unsere Unsere NNP cord-015369-72cjogxz 976 2 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 976 3 mit mit NNP cord-015369-72cjogxz 976 4 dieser dieser NNP cord-015369-72cjogxz 976 5 Methode Methode NNP cord-015369-72cjogxz 976 6 werden werden NNP cord-015369-72cjogxz 976 7 dargestellt dargestellt NNP cord-015369-72cjogxz 976 8 . . . cord-015369-72cjogxz 977 1 Methodik Methodik NNP cord-015369-72cjogxz 977 2 . . . cord-015369-72cjogxz 978 1 In in IN cord-015369-72cjogxz 978 2 einer einer DT cord-015369-72cjogxz 978 3 single single JJ cord-015369-72cjogxz 978 4 center center NN cord-015369-72cjogxz 978 5 Studie Studie NNP cord-015369-72cjogxz 978 6 wurden wurden VBD cord-015369-72cjogxz 978 7 Patienten Patienten NNP cord-015369-72cjogxz 978 8 , , , cord-015369-72cjogxz 978 9 die die VBP cord-015369-72cjogxz 978 10 von von NNP cord-015369-72cjogxz 978 11 August August NNP cord-015369-72cjogxz 978 12 2002 2002 CD cord-015369-72cjogxz 979 1 bis bis NNP cord-015369-72cjogxz 979 2 November November NNP cord-015369-72cjogxz 979 3 2006 2006 CD cord-015369-72cjogxz 979 4 einer einer NNP cord-015369-72cjogxz 979 5 lap lap NN cord-015369-72cjogxz 979 6 . . . cord-015369-72cjogxz 980 1 IPOM IPOM NNP cord-015369-72cjogxz 980 2 unterzogen unterzogen NNP cord-015369-72cjogxz 980 3 wurden wurden NNP cord-015369-72cjogxz 980 4 , , , cord-015369-72cjogxz 980 5 retrospektiv retrospektiv NNP cord-015369-72cjogxz 980 6 untersucht untersucht NNP cord-015369-72cjogxz 980 7 . . . cord-015369-72cjogxz 981 1 ( ( -LRB- cord-015369-72cjogxz 981 2 Demographische Demographische NNP cord-015369-72cjogxz 981 3 Daten Daten NNP cord-015369-72cjogxz 981 4 , , , cord-015369-72cjogxz 981 5 Comorbiditäten Comorbiditäten NNP cord-015369-72cjogxz 981 6 , , , cord-015369-72cjogxz 981 7 Art Art NNP cord-015369-72cjogxz 981 8 und und IN cord-015369-72cjogxz 981 9 Größe Größe NNP cord-015369-72cjogxz 981 10 der der NNP cord-015369-72cjogxz 981 11 Narbenhernien Narbenhernien NNP cord-015369-72cjogxz 981 12 und und IN cord-015369-72cjogxz 981 13 Netze Netze NNP cord-015369-72cjogxz 981 14 , , , cord-015369-72cjogxz 981 15 Art Art NNP cord-015369-72cjogxz 981 16 der der NN cord-015369-72cjogxz 981 17 Fixation Fixation NNP cord-015369-72cjogxz 981 18 , , , cord-015369-72cjogxz 981 19 Operationszeiten Operationszeiten NNP cord-015369-72cjogxz 981 20 , , , cord-015369-72cjogxz 981 21 stationärer stationärer NN cord-015369-72cjogxz 981 22 Aufenthaltsdauer Aufenthaltsdauer NNP cord-015369-72cjogxz 981 23 , , , cord-015369-72cjogxz 981 24 Komplikationen Komplikationen NNP cord-015369-72cjogxz 981 25 , , , cord-015369-72cjogxz 981 26 Rezidive Rezidive NNP cord-015369-72cjogxz 981 27 . . . cord-015369-72cjogxz 981 28 ) ) -RRB- cord-015369-72cjogxz 982 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 982 2 . . . cord-015369-72cjogxz 983 1 Es Es NNP cord-015369-72cjogxz 983 2 wurden wurden VBD cord-015369-72cjogxz 983 3 118 118 CD cord-015369-72cjogxz 983 4 Patienten Patienten NNP cord-015369-72cjogxz 983 5 in in IN cord-015369-72cjogxz 983 6 die die JJ cord-015369-72cjogxz 983 7 Studie Studie NNP cord-015369-72cjogxz 983 8 eingeschlossen eingeschlossen NNP cord-015369-72cjogxz 983 9 . . . cord-015369-72cjogxz 984 1 Das Das NNP cord-015369-72cjogxz 984 2 durchschnittliche durchschnittliche NN cord-015369-72cjogxz 984 3 Alter Alter NNP cord-015369-72cjogxz 984 4 der der NNP cord-015369-72cjogxz 984 5 Patienten Patienten NNP cord-015369-72cjogxz 984 6 betrug betrug NNP cord-015369-72cjogxz 984 7 63 63 CD cord-015369-72cjogxz 984 8 Jahre Jahre NNP cord-015369-72cjogxz 984 9 ; ; : cord-015369-72cjogxz 984 10 der der NNP cord-015369-72cjogxz 984 11 mittlere mittlere NNP cord-015369-72cjogxz 984 12 BMI BMI NNP cord-015369-72cjogxz 984 13 lag lag VBP cord-015369-72cjogxz 984 14 bei bei NNP cord-015369-72cjogxz 984 15 28 28 CD cord-015369-72cjogxz 984 16 . . . cord-015369-72cjogxz 985 1 16 16 CD cord-015369-72cjogxz 985 2 % % NN cord-015369-72cjogxz 985 3 aller aller NNP cord-015369-72cjogxz 985 4 Patienten Patienten NNP cord-015369-72cjogxz 985 5 litten litten VBD cord-015369-72cjogxz 985 6 an an DT cord-015369-72cjogxz 985 7 Diabetes diabetes NN cord-015369-72cjogxz 985 8 , , , cord-015369-72cjogxz 985 9 während während JJ cord-015369-72cjogxz 985 10 9 9 CD cord-015369-72cjogxz 985 11 % % NN cord-015369-72cjogxz 985 12 eine eine NNP cord-015369-72cjogxz 985 13 COPD COPD NNP cord-015369-72cjogxz 985 14 aufwiesen aufwiesen NNP cord-015369-72cjogxz 985 15 . . . cord-015369-72cjogxz 986 1 Die die VB cord-015369-72cjogxz 986 2 mittlere mittlere NNP cord-015369-72cjogxz 986 3 Operationszeit Operationszeit NNP cord-015369-72cjogxz 986 4 betrug betrug NNP cord-015369-72cjogxz 986 5 102 102 CD cord-015369-72cjogxz 986 6 Minuten Minuten NNP cord-015369-72cjogxz 986 7 . . . cord-015369-72cjogxz 987 1 In in IN cord-015369-72cjogxz 987 2 71 71 CD cord-015369-72cjogxz 987 3 % % NN cord-015369-72cjogxz 987 4 aller aller NNP cord-015369-72cjogxz 987 5 Patienten Patienten NNP cord-015369-72cjogxz 987 6 wurde wurde NNP cord-015369-72cjogxz 987 7 ein ein NNP cord-015369-72cjogxz 987 8 Polyester Polyester NNP cord-015369-72cjogxz 987 9 Netz Netz NNP cord-015369-72cjogxz 987 10 verwendet verwendet NNP cord-015369-72cjogxz 987 11 , , , cord-015369-72cjogxz 987 12 in in IN cord-015369-72cjogxz 987 13 25 25 CD cord-015369-72cjogxz 987 14 % % NN cord-015369-72cjogxz 987 15 ein ein NN cord-015369-72cjogxz 987 16 ePTFE ePTFE NNP cord-015369-72cjogxz 987 17 Netz Netz NNP cord-015369-72cjogxz 987 18 . . . cord-015369-72cjogxz 988 1 Bei Bei NNP cord-015369-72cjogxz 988 2 33 33 CD cord-015369-72cjogxz 989 1 Patienten Patienten NNP cord-015369-72cjogxz 989 2 traten traten NNP cord-015369-72cjogxz 989 3 insgesamt insgesamt NNP cord-015369-72cjogxz 989 4 38 38 CD cord-015369-72cjogxz 990 1 Komplikationen Komplikationen NNP cord-015369-72cjogxz 990 2 auf auf NNP cord-015369-72cjogxz 990 3 . . . cord-015369-72cjogxz 991 1 Die die VB cord-015369-72cjogxz 991 2 häufigsten häufigsten NNP cord-015369-72cjogxz 991 3 Komplikationen Komplikationen NNP cord-015369-72cjogxz 991 4 waren waren NNP cord-015369-72cjogxz 991 5 Serome Serome NNP cord-015369-72cjogxz 991 6 ( ( -LRB- cord-015369-72cjogxz 991 7 16,5 16,5 CD cord-015369-72cjogxz 991 8 % % NN cord-015369-72cjogxz 991 9 ) ) -RRB- cord-015369-72cjogxz 992 1 und und IN cord-015369-72cjogxz 992 2 Hämatome Hämatome NNP cord-015369-72cjogxz 992 3 ( ( -LRB- cord-015369-72cjogxz 992 4 9 9 CD cord-015369-72cjogxz 992 5 % % NN cord-015369-72cjogxz 992 6 ) ) -RRB- cord-015369-72cjogxz 992 7 . . . cord-015369-72cjogxz 993 1 2,5 2,5 CD cord-015369-72cjogxz 993 2 % % NN cord-015369-72cjogxz 993 3 aller aller NNP cord-015369-72cjogxz 993 4 Patienten Patienten NNP cord-015369-72cjogxz 993 5 wiesen wiesen XX cord-015369-72cjogxz 993 6 postoperativ postoperativ NNP cord-015369-72cjogxz 993 7 länger länger NNP cord-015369-72cjogxz 993 8 andauernde andauernde NNP cord-015369-72cjogxz 993 9 Schmerzen Schmerzen NNP cord-015369-72cjogxz 993 10 auf auf NNP cord-015369-72cjogxz 993 11 . . . cord-015369-72cjogxz 994 1 In in IN cord-015369-72cjogxz 994 2 2,5 2,5 CD cord-015369-72cjogxz 994 3 % % NN cord-015369-72cjogxz 994 4 kam kam NNP cord-015369-72cjogxz 994 5 es es XX cord-015369-72cjogxz 994 6 zum zum NNP cord-015369-72cjogxz 994 7 Auftreten Auftreten NNP cord-015369-72cjogxz 994 8 eines eines NNPS cord-015369-72cjogxz 994 9 Ileus Ileus NNP cord-015369-72cjogxz 994 10 aufgrund aufgrund VBP cord-015369-72cjogxz 994 11 von von NNP cord-015369-72cjogxz 994 12 Adhäsionen Adhäsionen NNP cord-015369-72cjogxz 994 13 oder oder NNP cord-015369-72cjogxz 994 14 Inkarzeration Inkarzeration NNP cord-015369-72cjogxz 994 15 . . . cord-015369-72cjogxz 995 1 Netzinfektionen Netzinfektionen NNP cord-015369-72cjogxz 995 2 und und XX cord-015369-72cjogxz 996 1 Netzausrisse Netzausrisse NNP cord-015369-72cjogxz 996 2 traten traten NNP cord-015369-72cjogxz 996 3 jeweils jeweils NNP cord-015369-72cjogxz 996 4 bei bei NNP cord-015369-72cjogxz 996 5 1,7 1,7 CD cord-015369-72cjogxz 996 6 % % NN cord-015369-72cjogxz 996 7 aller aller NNP cord-015369-72cjogxz 996 8 Patienten Patienten NNP cord-015369-72cjogxz 996 9 auf auf NNP cord-015369-72cjogxz 996 10 . . . cord-015369-72cjogxz 997 1 Netzinfektionen Netzinfektionen NNP cord-015369-72cjogxz 997 2 fü fü IN cord-015369-72cjogxz 997 3 hrten hrten NNP cord-015369-72cjogxz 997 4 stets stets NNP cord-015369-72cjogxz 997 5 zum zum NNP cord-015369-72cjogxz 997 6 operativen operativen NNP cord-015369-72cjogxz 997 7 Ausbau Ausbau NNP cord-015369-72cjogxz 997 8 der der NNP cord-015369-72cjogxz 997 9 Implantate Implantate NNP cord-015369-72cjogxz 997 10 . . . cord-015369-72cjogxz 998 1 Ein Ein NNP cord-015369-72cjogxz 998 2 Patient Patient NNP cord-015369-72cjogxz 998 3 verstarb verstarb NN cord-015369-72cjogxz 998 4 am be VBP cord-015369-72cjogxz 998 5 vierten vierten NNP cord-015369-72cjogxz 998 6 postoperativen postoperativen NNP cord-015369-72cjogxz 999 1 Tag tag VB cord-015369-72cjogxz 999 2 an an DT cord-015369-72cjogxz 999 3 einem einem NNP cord-015369-72cjogxz 999 4 Multiorganversagen Multiorganversagen NNP cord-015369-72cjogxz 999 5 aufgrund aufgrund IN cord-015369-72cjogxz 999 6 einer einer NNP cord-015369-72cjogxz 999 7 Darmperforation Darmperforation NNP cord-015369-72cjogxz 999 8 . . . cord-015369-72cjogxz 1000 1 Nach Nach NNP cord-015369-72cjogxz 1000 2 einem einem NNP cord-015369-72cjogxz 1000 3 medianen medianen NNP cord-015369-72cjogxz 1000 4 follow follow NN cord-015369-72cjogxz 1000 5 - - HYPH cord-015369-72cjogxz 1000 6 up up NN cord-015369-72cjogxz 1001 1 von von NNP cord-015369-72cjogxz 1001 2 40 40 CD cord-015369-72cjogxz 1002 1 Monaten Monaten NNP cord-015369-72cjogxz 1002 2 kam kam NNP cord-015369-72cjogxz 1002 3 es es XX cord-015369-72cjogxz 1002 4 bei bei NNP cord-015369-72cjogxz 1003 1 9 9 CD cord-015369-72cjogxz 1003 2 % % NN cord-015369-72cjogxz 1003 3 der der NN cord-015369-72cjogxz 1003 4 Patienten Patienten NNP cord-015369-72cjogxz 1003 5 zu zu NNP cord-015369-72cjogxz 1003 6 einem einem NNP cord-015369-72cjogxz 1003 7 Rezidiv Rezidiv NNP cord-015369-72cjogxz 1003 8 . . . cord-015369-72cjogxz 1004 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1004 2 . . . cord-015369-72cjogxz 1005 1 Die Die NNP cord-015369-72cjogxz 1005 2 Komplikations Komplikations NNP cord-015369-72cjogxz 1005 3 - - HYPH cord-015369-72cjogxz 1005 4 und und NNP cord-015369-72cjogxz 1005 5 Rezidivrate Rezidivrate NNP cord-015369-72cjogxz 1005 6 in in IN cord-015369-72cjogxz 1005 7 dieser dieser NNP cord-015369-72cjogxz 1005 8 ersten ersten FW cord-015369-72cjogxz 1005 9 Serie Serie NNP cord-015369-72cjogxz 1005 10 ist ist NNP cord-015369-72cjogxz 1005 11 mit mit NNP cord-015369-72cjogxz 1005 12 den den NNP cord-015369-72cjogxz 1005 13 in in IN cord-015369-72cjogxz 1005 14 der der NNP cord-015369-72cjogxz 1005 15 Literatur Literatur NNP cord-015369-72cjogxz 1005 16 angegeben angegeben NN cord-015369-72cjogxz 1005 17 vergleichbar vergleichbar NN cord-015369-72cjogxz 1005 18 . . . cord-015369-72cjogxz 1006 1 Wir Wir NNP cord-015369-72cjogxz 1006 2 erachten erachten NNP cord-015369-72cjogxz 1006 3 die die VBP cord-015369-72cjogxz 1006 4 lap lap NN cord-015369-72cjogxz 1006 5 . . . cord-015369-72cjogxz 1007 1 IPOM IPOM NNP cord-015369-72cjogxz 1007 2 Technik Technik NNP cord-015369-72cjogxz 1007 3 für für IN cord-015369-72cjogxz 1007 4 eine eine NNP cord-015369-72cjogxz 1007 5 interessante interessante NNP cord-015369-72cjogxz 1007 6 Alternative Alternative NNP cord-015369-72cjogxz 1007 7 zu zu NNP cord-015369-72cjogxz 1007 8 herkömmlichen herkömmlichen NNP cord-015369-72cjogxz 1007 9 Verschlusstechniken Verschlusstechniken NNP cord-015369-72cjogxz 1007 10 . . . cord-015369-72cjogxz 1008 1 Comparison comparison NN cord-015369-72cjogxz 1008 2 of of IN cord-015369-72cjogxz 1008 3 different different JJ cord-015369-72cjogxz 1008 4 fixation fixation NN cord-015369-72cjogxz 1008 5 elements element NNS cord-015369-72cjogxz 1008 6 for for IN cord-015369-72cjogxz 1008 7 the the DT cord-015369-72cjogxz 1008 8 IPOM IPOM NNP cord-015369-72cjogxz 1008 9 procedure procedure NN cord-015369-72cjogxz 1008 10 in in IN cord-015369-72cjogxz 1008 11 a a DT cord-015369-72cjogxz 1008 12 rat rat NN cord-015369-72cjogxz 1008 13 model model NN cord-015369-72cjogxz 1008 14 Background background NN cord-015369-72cjogxz 1008 15 . . . cord-015369-72cjogxz 1009 1 Long long JJ cord-015369-72cjogxz 1009 2 - - HYPH cord-015369-72cjogxz 1009 3 time time NN cord-015369-72cjogxz 1009 4 complications complication NNS cord-015369-72cjogxz 1009 5 after after IN cord-015369-72cjogxz 1009 6 the the DT cord-015369-72cjogxz 1009 7 laparoscopic laparoscopic JJ cord-015369-72cjogxz 1009 8 IPOM IPOM NNP cord-015369-72cjogxz 1009 9 techniques technique NNS cord-015369-72cjogxz 1009 10 are be VBP cord-015369-72cjogxz 1009 11 adhesion adhesion NN cord-015369-72cjogxz 1009 12 formation formation NN cord-015369-72cjogxz 1009 13 and and CC cord-015369-72cjogxz 1009 14 recurrence recurrence NN cord-015369-72cjogxz 1009 15 . . . cord-015369-72cjogxz 1010 1 Because because IN cord-015369-72cjogxz 1010 2 of of IN cord-015369-72cjogxz 1010 3 the the DT cord-015369-72cjogxz 1010 4 intraperitoneal intraperitoneal JJ cord-015369-72cjogxz 1010 5 position position NN cord-015369-72cjogxz 1010 6 of of IN cord-015369-72cjogxz 1010 7 the the DT cord-015369-72cjogxz 1010 8 foreign foreign JJ cord-015369-72cjogxz 1010 9 body body NN cord-015369-72cjogxz 1010 10 , , , cord-015369-72cjogxz 1010 11 adhesions adhesion NNS cord-015369-72cjogxz 1010 12 could could MD cord-015369-72cjogxz 1010 13 lead lead VB cord-015369-72cjogxz 1010 14 to to IN cord-015369-72cjogxz 1010 15 severe severe JJ cord-015369-72cjogxz 1010 16 complications complication NNS cord-015369-72cjogxz 1010 17 like like IN cord-015369-72cjogxz 1010 18 ileus ileus NN cord-015369-72cjogxz 1010 19 or or CC cord-015369-72cjogxz 1010 20 fistula fistula NN cord-015369-72cjogxz 1010 21 formation formation NN cord-015369-72cjogxz 1010 22 . . . cord-015369-72cjogxz 1011 1 Equally equally RB cord-015369-72cjogxz 1011 2 insufficient insufficient JJ cord-015369-72cjogxz 1011 3 fixation fixation NN cord-015369-72cjogxz 1011 4 produces produce VBZ cord-015369-72cjogxz 1011 5 recurrent recurrent JJ cord-015369-72cjogxz 1011 6 hernias hernia NNS cord-015369-72cjogxz 1011 7 . . . cord-015369-72cjogxz 1012 1 Study study NN cord-015369-72cjogxz 1012 2 design design NN cord-015369-72cjogxz 1012 3 . . . cord-015369-72cjogxz 1013 1 Forty Forty NNP cord-015369-72cjogxz 1013 2 Sprague Sprague NNP cord-015369-72cjogxz 1013 3 - - HYPH cord-015369-72cjogxz 1013 4 Dawley Dawley NNP cord-015369-72cjogxz 1013 5 rats rat NNS cord-015369-72cjogxz 1013 6 were be VBD cord-015369-72cjogxz 1013 7 used use VBN cord-015369-72cjogxz 1013 8 in in IN cord-015369-72cjogxz 1013 9 this this DT cord-015369-72cjogxz 1013 10 two two CD cord-015369-72cjogxz 1013 11 - - HYPH cord-015369-72cjogxz 1013 12 phase phase NN cord-015369-72cjogxz 1013 13 , , , cord-015369-72cjogxz 1013 14 prospective prospective JJ cord-015369-72cjogxz 1013 15 randomized randomized JJ cord-015369-72cjogxz 1013 16 study study NN cord-015369-72cjogxz 1013 17 . . . cord-015369-72cjogxz 1014 1 Polypropylene polypropylene NN cord-015369-72cjogxz 1014 2 mesh mesh NN cord-015369-72cjogxz 1015 1 ( ( -LRB- cord-015369-72cjogxz 1015 2 Parietene Parietene NNP cord-015369-72cjogxz 1015 3 composix composix NNP cord-015369-72cjogxz 1015 4 ) ) -RRB- cord-015369-72cjogxz 1015 5 samples sample NNS cord-015369-72cjogxz 1015 6 were be VBD cord-015369-72cjogxz 1015 7 positioned position VBN cord-015369-72cjogxz 1015 8 intraperitoneal intraperitoneal JJ cord-015369-72cjogxz 1015 9 bilaterally bilaterally RB cord-015369-72cjogxz 1015 10 to to IN cord-015369-72cjogxz 1015 11 the the DT cord-015369-72cjogxz 1015 12 midline midline NN cord-015369-72cjogxz 1015 13 . . . cord-015369-72cjogxz 1016 1 The the DT cord-015369-72cjogxz 1016 2 randomized randomized JJ cord-015369-72cjogxz 1016 3 mesh mesh NN cord-015369-72cjogxz 1016 4 fixation fixation NN cord-015369-72cjogxz 1016 5 groups group NNS cord-015369-72cjogxz 1016 6 were be VBD cord-015369-72cjogxz 1016 7 suture suture NNP cord-015369-72cjogxz 1016 8 ( ( -LRB- cord-015369-72cjogxz 1016 9 SU SU NNP cord-015369-72cjogxz 1016 10 ) ) -RRB- cord-015369-72cjogxz 1016 11 , , , cord-015369-72cjogxz 1016 12 Protack Protack NNP cord-015369-72cjogxz 1016 13 ( ( -LRB- cord-015369-72cjogxz 1016 14 PT PT NNP cord-015369-72cjogxz 1016 15 ) ) -RRB- cord-015369-72cjogxz 1016 16 , , , cord-015369-72cjogxz 1016 17 Absorba Absorba NNP cord-015369-72cjogxz 1016 18 Tack Tack NNP cord-015369-72cjogxz 1016 19 ( ( -LRB- cord-015369-72cjogxz 1016 20 AT at IN cord-015369-72cjogxz 1016 21 ) ) -RRB- cord-015369-72cjogxz 1016 22 and and CC cord-015369-72cjogxz 1016 23 I I NNP cord-015369-72cjogxz 1016 24 - - HYPH cord-015369-72cjogxz 1016 25 Clip Clip NNP cord-015369-72cjogxz 1016 26 ( ( -LRB- cord-015369-72cjogxz 1016 27 IC IC NNP cord-015369-72cjogxz 1016 28 ) ) -RRB- cord-015369-72cjogxz 1016 29 . . . cord-015369-72cjogxz 1017 1 Half half NN cord-015369-72cjogxz 1017 2 of of IN cord-015369-72cjogxz 1017 3 the the DT cord-015369-72cjogxz 1017 4 rats rat NNS cord-015369-72cjogxz 1017 5 in in IN cord-015369-72cjogxz 1017 6 each each DT cord-015369-72cjogxz 1017 7 group group NN cord-015369-72cjogxz 1017 8 were be VBD cord-015369-72cjogxz 1017 9 sacrificed sacrifice VBN cord-015369-72cjogxz 1017 10 and and CC cord-015369-72cjogxz 1017 11 analyzed analyze VBD cord-015369-72cjogxz 1017 12 one one CD cord-015369-72cjogxz 1017 13 week week NN cord-015369-72cjogxz 1017 14 after after IN cord-015369-72cjogxz 1017 15 implantation implantation NN cord-015369-72cjogxz 1017 16 while while IN cord-015369-72cjogxz 1017 17 the the DT cord-015369-72cjogxz 1017 18 second second JJ cord-015369-72cjogxz 1017 19 half half NN cord-015369-72cjogxz 1017 20 were be VBD cord-015369-72cjogxz 1017 21 sacrificed sacrifice VBN cord-015369-72cjogxz 1017 22 and and CC cord-015369-72cjogxz 1017 23 analyzed analyze VBN cord-015369-72cjogxz 1017 24 after after IN cord-015369-72cjogxz 1017 25 two two CD cord-015369-72cjogxz 1017 26 months month NNS cord-015369-72cjogxz 1017 27 . . . cord-015369-72cjogxz 1018 1 Measured measure VBN cord-015369-72cjogxz 1018 2 parameters parameter NNS cord-015369-72cjogxz 1018 3 were be VBD cord-015369-72cjogxz 1018 4 strength strength NN cord-015369-72cjogxz 1018 5 of of IN cord-015369-72cjogxz 1018 6 incorporation incorporation NN cord-015369-72cjogxz 1018 7 ( ( -LRB- cord-015369-72cjogxz 1018 8 SOI SOI NNP cord-015369-72cjogxz 1018 9 ) ) -RRB- cord-015369-72cjogxz 1018 10 and and CC cord-015369-72cjogxz 1018 11 adhesion adhesion NN cord-015369-72cjogxz 1018 12 formations formation NNS cord-015369-72cjogxz 1018 13 . . . cord-015369-72cjogxz 1019 1 Results result NNS cord-015369-72cjogxz 1019 2 . . . cord-015369-72cjogxz 1020 1 After after IN cord-015369-72cjogxz 1020 2 one one CD cord-015369-72cjogxz 1020 3 week week NN cord-015369-72cjogxz 1020 4 the the DT cord-015369-72cjogxz 1020 5 SOI SOI NNP cord-015369-72cjogxz 1020 6 of of IN cord-015369-72cjogxz 1020 7 the the DT cord-015369-72cjogxz 1020 8 SU SU NNP cord-015369-72cjogxz 1020 9 fixation fixation NN cord-015369-72cjogxz 1020 10 was be VBD cord-015369-72cjogxz 1020 11 significantly significantly RB cord-015369-72cjogxz 1020 12 higher high JJR cord-015369-72cjogxz 1020 13 than than IN cord-015369-72cjogxz 1020 14 for for IN cord-015369-72cjogxz 1020 15 all all DT cord-015369-72cjogxz 1020 16 other other JJ cord-015369-72cjogxz 1020 17 groups group NNS cord-015369-72cjogxz 1020 18 . . . cord-015369-72cjogxz 1021 1 Between between IN cord-015369-72cjogxz 1021 2 PT PT NNP cord-015369-72cjogxz 1021 3 and and CC cord-015369-72cjogxz 1021 4 AT at IN cord-015369-72cjogxz 1021 5 the the DT cord-015369-72cjogxz 1021 6 SOI SOI NNP cord-015369-72cjogxz 1021 7 was be VBD cord-015369-72cjogxz 1021 8 equally equally RB cord-015369-72cjogxz 1021 9 and and CC cord-015369-72cjogxz 1021 10 significantly significantly RB cord-015369-72cjogxz 1021 11 higher high JJR cord-015369-72cjogxz 1021 12 than than IN cord-015369-72cjogxz 1021 13 in in IN cord-015369-72cjogxz 1021 14 the the DT cord-015369-72cjogxz 1021 15 IC IC NNP cord-015369-72cjogxz 1021 16 group group NN cord-015369-72cjogxz 1021 17 . . . cord-015369-72cjogxz 1022 1 After after IN cord-015369-72cjogxz 1022 2 two two CD cord-015369-72cjogxz 1022 3 months month NNS cord-015369-72cjogxz 1022 4 again again RB cord-015369-72cjogxz 1022 5 the the DT cord-015369-72cjogxz 1022 6 SOI SOI NNP cord-015369-72cjogxz 1022 7 from from IN cord-015369-72cjogxz 1022 8 the the DT cord-015369-72cjogxz 1022 9 SU SU NNP cord-015369-72cjogxz 1022 10 was be VBD cord-015369-72cjogxz 1022 11 significantly significantly RB cord-015369-72cjogxz 1022 12 stronger strong JJR cord-015369-72cjogxz 1022 13 than than IN cord-015369-72cjogxz 1022 14 the the DT cord-015369-72cjogxz 1022 15 two two CD cord-015369-72cjogxz 1022 16 fixation fixation NN cord-015369-72cjogxz 1022 17 groups group NNS cord-015369-72cjogxz 1022 18 PT PT NNP cord-015369-72cjogxz 1022 19 and and CC cord-015369-72cjogxz 1022 20 AT AT NNP cord-015369-72cjogxz 1022 21 . . . cord-015369-72cjogxz 1023 1 IC IC NNP cord-015369-72cjogxz 1023 2 was be VBD cord-015369-72cjogxz 1023 3 poorly poorly RB cord-015369-72cjogxz 1023 4 incorporated incorporate VBN cord-015369-72cjogxz 1023 5 resulting result VBG cord-015369-72cjogxz 1023 6 in in IN cord-015369-72cjogxz 1023 7 few few JJ cord-015369-72cjogxz 1023 8 SOI soi NN cord-015369-72cjogxz 1023 9 . . . cord-015369-72cjogxz 1024 1 Inflammatory inflammatory JJ cord-015369-72cjogxz 1024 2 reactions reaction NNS cord-015369-72cjogxz 1024 3 were be VBD cord-015369-72cjogxz 1024 4 considerably considerably RB cord-015369-72cjogxz 1024 5 more more RBR cord-015369-72cjogxz 1024 6 severe severe JJ cord-015369-72cjogxz 1024 7 after after IN cord-015369-72cjogxz 1024 8 one one CD cord-015369-72cjogxz 1024 9 week week NN cord-015369-72cjogxz 1024 10 than than IN cord-015369-72cjogxz 1024 11 after after IN cord-015369-72cjogxz 1024 12 two two CD cord-015369-72cjogxz 1024 13 months month NNS cord-015369-72cjogxz 1024 14 . . . cord-015369-72cjogxz 1025 1 Adhesion adhesion NN cord-015369-72cjogxz 1025 2 formations formation NNS cord-015369-72cjogxz 1025 3 were be VBD cord-015369-72cjogxz 1025 4 significantly significantly RB cord-015369-72cjogxz 1025 5 stronger strong JJR cord-015369-72cjogxz 1025 6 in in IN cord-015369-72cjogxz 1025 7 the the DT cord-015369-72cjogxz 1025 8 groups group NNS cord-015369-72cjogxz 1025 9 SU SU NNP cord-015369-72cjogxz 1025 10 and and CC cord-015369-72cjogxz 1025 11 PT PT NNP cord-015369-72cjogxz 1025 12 compared compare VBN cord-015369-72cjogxz 1025 13 to to IN cord-015369-72cjogxz 1025 14 AT AT NNP cord-015369-72cjogxz 1025 15 and and CC cord-015369-72cjogxz 1025 16 IC IC NNP cord-015369-72cjogxz 1025 17 . . . cord-015369-72cjogxz 1026 1 Conclusions conclusion NNS cord-015369-72cjogxz 1026 2 . . . cord-015369-72cjogxz 1027 1 IC IC NNP cord-015369-72cjogxz 1027 2 showed show VBD cord-015369-72cjogxz 1027 3 unacceptable unacceptable JJ cord-015369-72cjogxz 1027 4 SOI SOI NNP cord-015369-72cjogxz 1027 5 and and CC cord-015369-72cjogxz 1027 6 should should MD cord-015369-72cjogxz 1027 7 not not RB cord-015369-72cjogxz 1027 8 be be VB cord-015369-72cjogxz 1027 9 used use VBN cord-015369-72cjogxz 1027 10 for for IN cord-015369-72cjogxz 1027 11 mesh mesh NN cord-015369-72cjogxz 1027 12 fixation fixation NN cord-015369-72cjogxz 1027 13 . . . cord-015369-72cjogxz 1028 1 AT at IN cord-015369-72cjogxz 1028 2 leads lead VBZ cord-015369-72cjogxz 1028 3 only only RB cord-015369-72cjogxz 1028 4 to to IN cord-015369-72cjogxz 1028 5 few few JJ cord-015369-72cjogxz 1028 6 adhesions adhesion NNS cord-015369-72cjogxz 1028 7 compared compare VBN cord-015369-72cjogxz 1028 8 to to IN cord-015369-72cjogxz 1028 9 the the DT cord-015369-72cjogxz 1028 10 nonabsorbable nonabsorbable JJ cord-015369-72cjogxz 1028 11 SU SU NNP cord-015369-72cjogxz 1028 12 and and CC cord-015369-72cjogxz 1028 13 PT PT NNP cord-015369-72cjogxz 1028 14 . . . cord-015369-72cjogxz 1029 1 To to TO cord-015369-72cjogxz 1029 2 have have VB cord-015369-72cjogxz 1029 3 a a DT cord-015369-72cjogxz 1029 4 good good JJ cord-015369-72cjogxz 1029 5 fixation fixation NN cord-015369-72cjogxz 1029 6 and and CC cord-015369-72cjogxz 1029 7 less less JJR cord-015369-72cjogxz 1029 8 adhesions adhesion NNS cord-015369-72cjogxz 1029 9 , , , cord-015369-72cjogxz 1029 10 a a DT cord-015369-72cjogxz 1029 11 combination combination NN cord-015369-72cjogxz 1029 12 of of IN cord-015369-72cjogxz 1029 13 different different JJ cord-015369-72cjogxz 1029 14 fixation fixation NN cord-015369-72cjogxz 1029 15 systems system NNS cord-015369-72cjogxz 1029 16 should should MD cord-015369-72cjogxz 1029 17 be be VB cord-015369-72cjogxz 1029 18 used use VBN cord-015369-72cjogxz 1029 19 . . . cord-015369-72cjogxz 1030 1 Background background NN cord-015369-72cjogxz 1030 2 . . . cord-015369-72cjogxz 1031 1 Research research NN cord-015369-72cjogxz 1031 2 in in IN cord-015369-72cjogxz 1031 3 hernia hernia NN cord-015369-72cjogxz 1031 4 repair repair NN cord-015369-72cjogxz 1031 5 has have VBZ cord-015369-72cjogxz 1031 6 targeted target VBN cord-015369-72cjogxz 1031 7 new new JJ cord-015369-72cjogxz 1031 8 atraumatic atraumatic JJ cord-015369-72cjogxz 1031 9 mesh mesh NN cord-015369-72cjogxz 1031 10 fixation fixation NN cord-015369-72cjogxz 1031 11 techniques technique NNS cord-015369-72cjogxz 1031 12 like like IN cord-015369-72cjogxz 1031 13 surgical surgical JJ cord-015369-72cjogxz 1031 14 adhesives adhesive NNS cord-015369-72cjogxz 1031 15 to to TO cord-015369-72cjogxz 1031 16 reduce reduce VB cord-015369-72cjogxz 1031 17 major major JJ cord-015369-72cjogxz 1031 18 complications complication NNS cord-015369-72cjogxz 1031 19 like like IN cord-015369-72cjogxz 1031 20 chronic chronic JJ cord-015369-72cjogxz 1031 21 pain pain NN cord-015369-72cjogxz 1031 22 and and CC cord-015369-72cjogxz 1031 23 adhesion adhesion NN cord-015369-72cjogxz 1031 24 formation formation NN cord-015369-72cjogxz 1031 25 . . . cord-015369-72cjogxz 1032 1 The the DT cord-015369-72cjogxz 1032 2 efficacy efficacy NN cord-015369-72cjogxz 1032 3 and and CC cord-015369-72cjogxz 1032 4 safety safety NN cord-015369-72cjogxz 1032 5 of of IN cord-015369-72cjogxz 1032 6 two two CD cord-015369-72cjogxz 1032 7 adhesives adhesive NNS cord-015369-72cjogxz 1032 8 , , , cord-015369-72cjogxz 1032 9 e.g. e.g. RB cord-015369-72cjogxz 1032 10 Artiss Artiss NNP cord-015369-72cjogxz 1032 11 + + CC cord-015369-72cjogxz 1032 12 fibrin fibrin NN cord-015369-72cjogxz 1032 13 sealant sealant NN cord-015369-72cjogxz 1032 14 ( ( -LRB- cord-015369-72cjogxz 1032 15 FS fs NN cord-015369-72cjogxz 1032 16 ; ; : cord-015369-72cjogxz 1032 17 4 4 CD cord-015369-72cjogxz 1032 18 IU IU NNP cord-015369-72cjogxz 1032 19 Thrombin Thrombin NNP cord-015369-72cjogxz 1032 20 , , , cord-015369-72cjogxz 1032 21 Baxter Baxter NNP cord-015369-72cjogxz 1032 22 , , , cord-015369-72cjogxz 1032 23 Austria Austria NNP cord-015369-72cjogxz 1032 24 ) ) -RRB- cord-015369-72cjogxz 1032 25 and and CC cord-015369-72cjogxz 1032 26 Bioglue Bioglue NNP cord-015369-72cjogxz 1032 27 + + CC cord-015369-72cjogxz 1032 28 ( ( -LRB- cord-015369-72cjogxz 1032 29 BG BG NNP cord-015369-72cjogxz 1032 30 ; ; : cord-015369-72cjogxz 1032 31 Cryolife Cryolife NNP cord-015369-72cjogxz 1032 32 , , , cord-015369-72cjogxz 1032 33 USA USA NNP cord-015369-72cjogxz 1032 34 ) ) -RRB- cord-015369-72cjogxz 1032 35 were be VBD cord-015369-72cjogxz 1032 36 evaluated evaluate VBN cord-015369-72cjogxz 1032 37 in in IN cord-015369-72cjogxz 1032 38 this this DT cord-015369-72cjogxz 1032 39 study study NN cord-015369-72cjogxz 1032 40 . . . cord-015369-72cjogxz 1033 1 Study study NN cord-015369-72cjogxz 1033 2 endpoints endpoint NNS cord-015369-72cjogxz 1033 3 were be VBD cord-015369-72cjogxz 1033 4 tissue tissue NN cord-015369-72cjogxz 1033 5 integration integration NN cord-015369-72cjogxz 1033 6 and and CC cord-015369-72cjogxz 1033 7 foreign foreign JJ cord-015369-72cjogxz 1033 8 body body NN cord-015369-72cjogxz 1033 9 reaction reaction NN cord-015369-72cjogxz 1033 10 . . . cord-015369-72cjogxz 1034 1 Adhesion adhesion NN cord-015369-72cjogxz 1034 2 formation formation NN cord-015369-72cjogxz 1034 3 formed form VBD cord-015369-72cjogxz 1034 4 the the DT cord-015369-72cjogxz 1034 5 secondary secondary JJ cord-015369-72cjogxz 1034 6 outcome outcome NN cord-015369-72cjogxz 1034 7 parameter parameter NN cord-015369-72cjogxz 1034 8 . . . cord-015369-72cjogxz 1035 1 Methods method NNS cord-015369-72cjogxz 1035 2 . . . cord-015369-72cjogxz 1036 1 Twelve twelve CD cord-015369-72cjogxz 1036 2 rats rat NNS cord-015369-72cjogxz 1036 3 were be VBD cord-015369-72cjogxz 1036 4 randomized randomize VBN cord-015369-72cjogxz 1036 5 to to IN cord-015369-72cjogxz 1036 6 3 3 CD cord-015369-72cjogxz 1036 7 groups group NNS cord-015369-72cjogxz 1036 8 ( ( -LRB- cord-015369-72cjogxz 1036 9 n n CC cord-015369-72cjogxz 1036 10 ¼ ¼ NNP cord-015369-72cjogxz 1036 11 6 6 CD cord-015369-72cjogxz 1036 12 ) ) -RRB- cord-015369-72cjogxz 1036 13 . . . cord-015369-72cjogxz 1037 1 2 2 CD cord-015369-72cjogxz 1037 2 groups group NNS cord-015369-72cjogxz 1037 3 of of IN cord-015369-72cjogxz 1037 4 onlay onlay NNP cord-015369-72cjogxz 1037 5 hernia hernia NN cord-015369-72cjogxz 1037 6 repair repair NN cord-015369-72cjogxz 1037 7 -mesh -mesh DT cord-015369-72cjogxz 1037 8 fixation fixation NN cord-015369-72cjogxz 1037 9 with with IN cord-015369-72cjogxz 1037 10 FS FS NNP cord-015369-72cjogxz 1037 11 ( ( -LRB- cord-015369-72cjogxz 1037 12 group group NN cord-015369-72cjogxz 1037 13 1 1 CD cord-015369-72cjogxz 1037 14 ) ) -RRB- cord-015369-72cjogxz 1037 15 or or CC cord-015369-72cjogxz 1037 16 BG BG NNP cord-015369-72cjogxz 1037 17 ( ( -LRB- cord-015369-72cjogxz 1037 18 group group NN cord-015369-72cjogxz 1037 19 2 2 CD cord-015369-72cjogxz 1037 20 ) ) -RRB- cord-015369-72cjogxz 1037 21 , , , cord-015369-72cjogxz 1037 22 one one CD cord-015369-72cjogxz 1037 23 group group NN cord-015369-72cjogxz 1037 24 of of IN cord-015369-72cjogxz 1038 1 IPOM IPOM NNP cord-015369-72cjogxz 1038 2 repair repair VBP cord-015369-72cjogxz 1038 3 -mesh -mesh DT cord-015369-72cjogxz 1038 4 fixation fixation NN cord-015369-72cjogxz 1038 5 with with IN cord-015369-72cjogxz 1038 6 4 4 CD cord-015369-72cjogxz 1038 7 sutures suture NNS cord-015369-72cjogxz 1038 8 and and CC cord-015369-72cjogxz 1038 9 BG BG NNP cord-015369-72cjogxz 1038 10 ( ( -LRB- cord-015369-72cjogxz 1038 11 group group NN cord-015369-72cjogxz 1038 12 3 3 CD cord-015369-72cjogxz 1038 13 ) ) -RRB- cord-015369-72cjogxz 1038 14 . . . cord-015369-72cjogxz 1039 1 Follow follow VB cord-015369-72cjogxz 1039 2 up up RP cord-015369-72cjogxz 1039 3 was be VBD cord-015369-72cjogxz 1039 4 30 30 CD cord-015369-72cjogxz 1039 5 days day NNS cord-015369-72cjogxz 1039 6 . . . cord-015369-72cjogxz 1040 1 Native native JJ cord-015369-72cjogxz 1040 2 rat rat NN cord-015369-72cjogxz 1040 3 tissue tissue NN cord-015369-72cjogxz 1040 4 served serve VBD cord-015369-72cjogxz 1040 5 as as IN cord-015369-72cjogxz 1040 6 control control NN cord-015369-72cjogxz 1040 7 . . . cord-015369-72cjogxz 1041 1 Macroscopical macroscopical JJ cord-015369-72cjogxz 1041 2 and and CC cord-015369-72cjogxz 1041 3 histological histological JJ cord-015369-72cjogxz 1041 4 assessment assessment NN cord-015369-72cjogxz 1041 5 was be VBD cord-015369-72cjogxz 1041 6 performed perform VBN cord-015369-72cjogxz 1041 7 . . . cord-015369-72cjogxz 1042 1 Results result NNS cord-015369-72cjogxz 1042 2 . . . cord-015369-72cjogxz 1043 1 Onlay onlay NN cord-015369-72cjogxz 1043 2 meshes mesh NNS cord-015369-72cjogxz 1043 3 fixed fix VBN cord-015369-72cjogxz 1043 4 with with IN cord-015369-72cjogxz 1043 5 FS FS NNP cord-015369-72cjogxz 1043 6 showed show VBD cord-015369-72cjogxz 1043 7 excellent excellent JJ cord-015369-72cjogxz 1043 8 results result NNS cord-015369-72cjogxz 1043 9 in in IN cord-015369-72cjogxz 1043 10 all all DT cord-015369-72cjogxz 1043 11 evaluation evaluation NN cord-015369-72cjogxz 1043 12 criteria criterion NNS cord-015369-72cjogxz 1043 13 ( ( -LRB- cord-015369-72cjogxz 1043 14 group group NN cord-015369-72cjogxz 1043 15 1 1 CD cord-015369-72cjogxz 1043 16 ) ) -RRB- cord-015369-72cjogxz 1043 17 . . . cord-015369-72cjogxz 1044 1 Samples sample NNS cord-015369-72cjogxz 1044 2 fixed fix VBN cord-015369-72cjogxz 1044 3 with with IN cord-015369-72cjogxz 1044 4 BG bg NN cord-015369-72cjogxz 1044 5 ( ( -LRB- cord-015369-72cjogxz 1044 6 group group NN cord-015369-72cjogxz 1044 7 2 2 CD cord-015369-72cjogxz 1044 8 , , , cord-015369-72cjogxz 1044 9 3 3 CD cord-015369-72cjogxz 1044 10 ) ) -RRB- cord-015369-72cjogxz 1044 11 showed show VBD cord-015369-72cjogxz 1044 12 extensive extensive JJ cord-015369-72cjogxz 1044 13 scar scar NN cord-015369-72cjogxz 1044 14 formation formation NN cord-015369-72cjogxz 1044 15 . . . cord-015369-72cjogxz 1045 1 No no DT cord-015369-72cjogxz 1045 2 dislocation dislocation NN cord-015369-72cjogxz 1045 3 and and CC cord-015369-72cjogxz 1045 4 no no DT cord-015369-72cjogxz 1045 5 seroma seroma NN cord-015369-72cjogxz 1045 6 formation formation NN cord-015369-72cjogxz 1045 7 was be VBD cord-015369-72cjogxz 1045 8 seen see VBN cord-015369-72cjogxz 1045 9 . . . cord-015369-72cjogxz 1046 1 All all DT cord-015369-72cjogxz 1046 2 of of IN cord-015369-72cjogxz 1046 3 these these DT cord-015369-72cjogxz 1046 4 samples sample NNS cord-015369-72cjogxz 1046 5 showed show VBD cord-015369-72cjogxz 1046 6 moderate moderate JJ cord-015369-72cjogxz 1046 7 to to IN cord-015369-72cjogxz 1046 8 severe severe JJ cord-015369-72cjogxz 1046 9 signs sign NNS cord-015369-72cjogxz 1046 10 of of IN cord-015369-72cjogxz 1046 11 inflammation inflammation NN cord-015369-72cjogxz 1046 12 with with IN cord-015369-72cjogxz 1046 13 abscess abscess NN cord-015369-72cjogxz 1046 14 formation formation NN cord-015369-72cjogxz 1046 15 in in IN cord-015369-72cjogxz 1046 16 all all DT cord-015369-72cjogxz 1046 17 samples sample NNS cord-015369-72cjogxz 1046 18 of of IN cord-015369-72cjogxz 1046 19 group group NN cord-015369-72cjogxz 1046 20 2 2 CD cord-015369-72cjogxz 1046 21 . . . cord-015369-72cjogxz 1047 1 Adhesion adhesion NN cord-015369-72cjogxz 1047 2 formation formation NN cord-015369-72cjogxz 1047 3 was be VBD cord-015369-72cjogxz 1047 4 scored score VBN cord-015369-72cjogxz 1047 5 moderate moderate JJ cord-015369-72cjogxz 1047 6 to to TO cord-015369-72cjogxz 1047 7 severe severe VB cord-015369-72cjogxz 1047 8 in in IN cord-015369-72cjogxz 1047 9 all all DT cord-015369-72cjogxz 1047 10 samples sample NNS cord-015369-72cjogxz 1047 11 of of IN cord-015369-72cjogxz 1047 12 group group NN cord-015369-72cjogxz 1047 13 3 3 CD cord-015369-72cjogxz 1047 14 . . . cord-015369-72cjogxz 1048 1 Histological histological JJ cord-015369-72cjogxz 1048 2 signs sign NNS cord-015369-72cjogxz 1048 3 of of IN cord-015369-72cjogxz 1048 4 a a DT cord-015369-72cjogxz 1048 5 moderate moderate JJ cord-015369-72cjogxz 1048 6 foreign foreign JJ cord-015369-72cjogxz 1048 7 body body NN cord-015369-72cjogxz 1048 8 reaction reaction NN cord-015369-72cjogxz 1048 9 as as RB cord-015369-72cjogxz 1048 10 well well RB cord-015369-72cjogxz 1048 11 as as IN cord-015369-72cjogxz 1048 12 detritus detritus NN cord-015369-72cjogxz 1048 13 and and CC cord-015369-72cjogxz 1048 14 remnants remnant NNS cord-015369-72cjogxz 1048 15 of of IN cord-015369-72cjogxz 1048 16 BG BG NNP cord-015369-72cjogxz 1048 17 were be VBD cord-015369-72cjogxz 1048 18 seen see VBN cord-015369-72cjogxz 1048 19 in in IN cord-015369-72cjogxz 1048 20 all all DT cord-015369-72cjogxz 1048 21 samples sample NNS cord-015369-72cjogxz 1048 22 fixed fix VBN cord-015369-72cjogxz 1048 23 with with IN cord-015369-72cjogxz 1048 24 BG BG NNP cord-015369-72cjogxz 1048 25 ( ( -LRB- cord-015369-72cjogxz 1048 26 group group NN cord-015369-72cjogxz 1048 27 2 2 CD cord-015369-72cjogxz 1048 28 , , , cord-015369-72cjogxz 1048 29 3 3 CD cord-015369-72cjogxz 1048 30 ) ) -RRB- cord-015369-72cjogxz 1048 31 . . . cord-015369-72cjogxz 1049 1 Conclusions conclusion NNS cord-015369-72cjogxz 1049 2 . . . cord-015369-72cjogxz 1050 1 Artiss Artiss NNP cord-015369-72cjogxz 1050 2 + + CC cord-015369-72cjogxz 1050 3 showed show VBD cord-015369-72cjogxz 1050 4 excellent excellent JJ cord-015369-72cjogxz 1050 5 mesh mesh NN cord-015369-72cjogxz 1050 6 fixation fixation NN cord-015369-72cjogxz 1050 7 and and CC cord-015369-72cjogxz 1050 8 biocompatibility biocompatibility NN cord-015369-72cjogxz 1050 9 in in IN cord-015369-72cjogxz 1050 10 onlay onlay NN cord-015369-72cjogxz 1050 11 hernia hernia NN cord-015369-72cjogxz 1050 12 repair repair NN cord-015369-72cjogxz 1050 13 . . . cord-015369-72cjogxz 1051 1 Bioglue Bioglue NNP cord-015369-72cjogxz 1051 2 + + CC cord-015369-72cjogxz 1051 3 yields yield NNS cord-015369-72cjogxz 1051 4 high high JJ cord-015369-72cjogxz 1051 5 adhesive adhesive NN cord-015369-72cjogxz 1051 6 strength strength NN cord-015369-72cjogxz 1051 7 , , , cord-015369-72cjogxz 1051 8 but but CC cord-015369-72cjogxz 1051 9 our -PRON- PRP$ cord-015369-72cjogxz 1051 10 macroscopical macroscopical JJ cord-015369-72cjogxz 1051 11 and and CC cord-015369-72cjogxz 1051 12 histological histological JJ cord-015369-72cjogxz 1051 13 results result NNS cord-015369-72cjogxz 1051 14 indicate indicate VBP cord-015369-72cjogxz 1051 15 a a DT cord-015369-72cjogxz 1051 16 reduced reduce VBN cord-015369-72cjogxz 1051 17 biocompatibility biocompatibility NN cord-015369-72cjogxz 1051 18 . . . cord-015369-72cjogxz 1052 1 Treatment treatment NN cord-015369-72cjogxz 1052 2 of of IN cord-015369-72cjogxz 1052 3 mesh mesh NN cord-015369-72cjogxz 1052 4 graft graft NN cord-015369-72cjogxz 1052 5 infection infection NN cord-015369-72cjogxz 1052 6 following follow VBG cord-015369-72cjogxz 1052 7 abdominal abdominal JJ cord-015369-72cjogxz 1052 8 hernia hernia NN cord-015369-72cjogxz 1052 9 repair repair NN cord-015369-72cjogxz 1052 10 -Risk -risk NN cord-015369-72cjogxz 1052 11 factor factor NN cord-015369-72cjogxz 1052 12 evaluation evaluation NN cord-015369-72cjogxz 1052 13 , , , cord-015369-72cjogxz 1052 14 role role NN cord-015369-72cjogxz 1052 15 of of IN cord-015369-72cjogxz 1052 16 the the DT cord-015369-72cjogxz 1052 17 V.A.C. V.A.C. NNP cord-015369-72cjogxz 1052 18 system system NN cord-015369-72cjogxz 1052 19 and and CC cord-015369-72cjogxz 1052 20 influence influence NN cord-015369-72cjogxz 1052 21 of of IN cord-015369-72cjogxz 1052 22 the the DT cord-015369-72cjogxz 1052 23 type type NN cord-015369-72cjogxz 1052 24 of of IN cord-015369-72cjogxz 1052 25 mesh mesh NNP cord-015369-72cjogxz 1052 26 useda useda NNP cord-015369-72cjogxz 1052 27 retrospective retrospective JJ cord-015369-72cjogxz 1052 28 analysis analysis NN cord-015369-72cjogxz 1052 29 of of IN cord-015369-72cjogxz 1052 30 476 476 CD cord-015369-72cjogxz 1052 31 operations operation NNS cord-015369-72cjogxz 1052 32 Background Background NNP cord-015369-72cjogxz 1052 33 . . . cord-015369-72cjogxz 1053 1 Commonly commonly RB cord-015369-72cjogxz 1053 2 , , , cord-015369-72cjogxz 1053 3 mesh mesh NN cord-015369-72cjogxz 1053 4 graft graft NN cord-015369-72cjogxz 1053 5 infections infection NNS cord-015369-72cjogxz 1053 6 after after IN cord-015369-72cjogxz 1053 7 hernia hernia NN cord-015369-72cjogxz 1053 8 repair repair NN cord-015369-72cjogxz 1053 9 are be VBP cord-015369-72cjogxz 1053 10 treated treat VBN cord-015369-72cjogxz 1053 11 by by IN cord-015369-72cjogxz 1053 12 rapid rapid JJ cord-015369-72cjogxz 1053 13 removal removal NN cord-015369-72cjogxz 1053 14 of of IN cord-015369-72cjogxz 1053 15 the the DT cord-015369-72cjogxz 1053 16 mesh mesh NN cord-015369-72cjogxz 1053 17 causing cause VBG cord-015369-72cjogxz 1053 18 high high JJ cord-015369-72cjogxz 1053 19 morbidity morbidity NN cord-015369-72cjogxz 1053 20 . . . cord-015369-72cjogxz 1054 1 New new JJ cord-015369-72cjogxz 1054 2 materials material NNS cord-015369-72cjogxz 1054 3 of of IN cord-015369-72cjogxz 1054 4 mesh mesh NN cord-015369-72cjogxz 1054 5 grafts graft NNS cord-015369-72cjogxz 1054 6 and and CC cord-015369-72cjogxz 1054 7 new new JJ cord-015369-72cjogxz 1054 8 procedures procedure NNS cord-015369-72cjogxz 1054 9 of of IN cord-015369-72cjogxz 1054 10 wound wound NN cord-015369-72cjogxz 1054 11 management management NN cord-015369-72cjogxz 1054 12 now now RB cord-015369-72cjogxz 1054 13 further further RB cord-015369-72cjogxz 1054 14 challenge challenge VBP cord-015369-72cjogxz 1054 15 the the DT cord-015369-72cjogxz 1054 16 need need NN cord-015369-72cjogxz 1054 17 for for IN cord-015369-72cjogxz 1054 18 mesh mesh NN cord-015369-72cjogxz 1054 19 removal removal NN cord-015369-72cjogxz 1054 20 . . . cord-015369-72cjogxz 1055 1 Risk risk NN cord-015369-72cjogxz 1055 2 factor factor NN cord-015369-72cjogxz 1055 3 based base VBN cord-015369-72cjogxz 1055 4 choice choice NN cord-015369-72cjogxz 1055 5 of of IN cord-015369-72cjogxz 1055 6 patients patient NNS cord-015369-72cjogxz 1055 7 selected select VBN cord-015369-72cjogxz 1055 8 for for IN cord-015369-72cjogxz 1055 9 initial initial JJ cord-015369-72cjogxz 1055 10 hernia hernia NN cord-015369-72cjogxz 1055 11 repair repair NN cord-015369-72cjogxz 1055 12 might may MD cord-015369-72cjogxz 1055 13 partially partially RB cord-015369-72cjogxz 1055 14 avoid avoid VB cord-015369-72cjogxz 1055 15 such such JJ cord-015369-72cjogxz 1055 16 complications complication NNS cord-015369-72cjogxz 1055 17 . . . cord-015369-72cjogxz 1056 1 Methods method NNS cord-015369-72cjogxz 1056 2 . . . cord-015369-72cjogxz 1057 1 Four four CD cord-015369-72cjogxz 1057 2 hundred hundred CD cord-015369-72cjogxz 1057 3 and and CC cord-015369-72cjogxz 1057 4 seventy seventy CD cord-015369-72cjogxz 1057 5 - - HYPH cord-015369-72cjogxz 1057 6 six six CD cord-015369-72cjogxz 1057 7 mesh mesh NN cord-015369-72cjogxz 1057 8 grafts graft NNS cord-015369-72cjogxz 1057 9 implanted implant VBN cord-015369-72cjogxz 1057 10 for for IN cord-015369-72cjogxz 1057 11 hernia hernia NN cord-015369-72cjogxz 1057 12 repair repair NN cord-015369-72cjogxz 1057 13 were be VBD cord-015369-72cjogxz 1057 14 retrospectively retrospectively RB cord-015369-72cjogxz 1057 15 analyzed analyze VBN cord-015369-72cjogxz 1057 16 to to TO cord-015369-72cjogxz 1057 17 determine determine VB cord-015369-72cjogxz 1057 18 risk risk NN cord-015369-72cjogxz 1057 19 factors factor NNS cord-015369-72cjogxz 1057 20 for for IN cord-015369-72cjogxz 1057 21 development development NN cord-015369-72cjogxz 1057 22 of of IN cord-015369-72cjogxz 1057 23 a a DT cord-015369-72cjogxz 1057 24 graft graft NN cord-015369-72cjogxz 1057 25 infection infection NN cord-015369-72cjogxz 1057 26 . . . cord-015369-72cjogxz 1058 1 We -PRON- PRP cord-015369-72cjogxz 1058 2 further further RB cord-015369-72cjogxz 1058 3 evaluated evaluate VBD cord-015369-72cjogxz 1058 4 the the DT cord-015369-72cjogxz 1058 5 outcome outcome NN cord-015369-72cjogxz 1058 6 of of IN cord-015369-72cjogxz 1058 7 infected infected JJ cord-015369-72cjogxz 1058 8 mesh mesh NN cord-015369-72cjogxz 1058 9 grafts graft NNS cord-015369-72cjogxz 1058 10 ( ( -LRB- cord-015369-72cjogxz 1058 11 n n NNP cord-015369-72cjogxz 1058 12 ¼ ¼ NNP cord-015369-72cjogxz 1058 13 31 31 CD cord-015369-72cjogxz 1058 14 ) ) -RRB- cord-015369-72cjogxz 1058 15 treated treat VBN cord-015369-72cjogxz 1058 16 by by IN cord-015369-72cjogxz 1058 17 best good JJS cord-015369-72cjogxz 1058 18 supportive supportive JJ cord-015369-72cjogxz 1058 19 care care NN cord-015369-72cjogxz 1058 20 including include VBG cord-015369-72cjogxz 1058 21 vacuum vacuum NN cord-015369-72cjogxz 1058 22 assisted assist VBN cord-015369-72cjogxz 1058 23 closure closure NN cord-015369-72cjogxz 1058 24 system system NN cord-015369-72cjogxz 1058 25 . . . cord-015369-72cjogxz 1059 1 Results result NNS cord-015369-72cjogxz 1059 2 . . . cord-015369-72cjogxz 1060 1 Risk risk NN cord-015369-72cjogxz 1060 2 factors factor NNS cord-015369-72cjogxz 1060 3 for for IN cord-015369-72cjogxz 1060 4 mesh mesh NN cord-015369-72cjogxz 1060 5 graft graft NN cord-015369-72cjogxz 1060 6 infection infection NN cord-015369-72cjogxz 1060 7 were be VBD cord-015369-72cjogxz 1060 8 body body NN cord-015369-72cjogxz 1060 9 mass mass NN cord-015369-72cjogxz 1060 10 index index NN cord-015369-72cjogxz 1060 11 ( ( -LRB- cord-015369-72cjogxz 1060 12 BMI BMI NNP cord-015369-72cjogxz 1060 13 ) ) -RRB- cord-015369-72cjogxz 1060 14 , , , cord-015369-72cjogxz 1060 15 operation operation NN cord-015369-72cjogxz 1060 16 time time NN cord-015369-72cjogxz 1060 17 for for IN cord-015369-72cjogxz 1060 18 hernia hernia NN cord-015369-72cjogxz 1060 19 repair repair NN cord-015369-72cjogxz 1060 20 and and CC cord-015369-72cjogxz 1060 21 the the DT cord-015369-72cjogxz 1060 22 size size NN cord-015369-72cjogxz 1060 23 of of IN cord-015369-72cjogxz 1060 24 the the DT cord-015369-72cjogxz 1060 25 hernia hernia NN cord-015369-72cjogxz 1060 26 . . . cord-015369-72cjogxz 1061 1 55 55 CD cord-015369-72cjogxz 1061 2 % % NN cord-015369-72cjogxz 1061 3 of of IN cord-015369-72cjogxz 1061 4 infected infected JJ cord-015369-72cjogxz 1061 5 mesh mesh NN cord-015369-72cjogxz 1061 6 grafts graft NNS cord-015369-72cjogxz 1061 7 could could MD cord-015369-72cjogxz 1061 8 be be VB cord-015369-72cjogxz 1061 9 preserved preserve VBN cord-015369-72cjogxz 1061 10 by by IN cord-015369-72cjogxz 1061 11 conservative conservative JJ cord-015369-72cjogxz 1061 12 means mean NNS cord-015369-72cjogxz 1061 13 . . . cord-015369-72cjogxz 1062 1 Preservation preservation NN cord-015369-72cjogxz 1062 2 was be VBD cord-015369-72cjogxz 1062 3 possible possible JJ cord-015369-72cjogxz 1062 4 for for IN cord-015369-72cjogxz 1062 5 100 100 CD cord-015369-72cjogxz 1062 6 % % NN cord-015369-72cjogxz 1062 7 of of IN cord-015369-72cjogxz 1062 8 polyglactin polyglactin NNP cord-015369-72cjogxz 1062 9 / / SYM cord-015369-72cjogxz 1062 10 polypropylene polypropylene NN cord-015369-72cjogxz 1062 11 mesh mesh NN cord-015369-72cjogxz 1062 12 as as IN cord-015369-72cjogxz 1062 13 compared compare VBN cord-015369-72cjogxz 1062 14 to to IN cord-015369-72cjogxz 1062 15 20 20 CD cord-015369-72cjogxz 1062 16 - - SYM cord-015369-72cjogxz 1062 17 23 23 CD cord-015369-72cjogxz 1062 18 % % NN cord-015369-72cjogxz 1062 19 for for IN cord-015369-72cjogxz 1062 20 non non JJ cord-015369-72cjogxz 1062 21 - - JJ cord-015369-72cjogxz 1062 22 absorbable absorbable JJ cord-015369-72cjogxz 1062 23 types type NNS cord-015369-72cjogxz 1062 24 of of IN cord-015369-72cjogxz 1062 25 meshes mesh NNS cord-015369-72cjogxz 1062 26 ( ( -LRB- cord-015369-72cjogxz 1062 27 p p NN cord-015369-72cjogxz 1062 28 < < XX cord-015369-72cjogxz 1062 29 0.0001 0.0001 CD cord-015369-72cjogxz 1062 30 ) ) -RRB- cord-015369-72cjogxz 1062 31 . . . cord-015369-72cjogxz 1063 1 Preserved preserve VBN cord-015369-72cjogxz 1063 2 mesh mesh NN cord-015369-72cjogxz 1063 3 graft graft NN cord-015369-72cjogxz 1063 4 showed show VBD cord-015369-72cjogxz 1063 5 no no DT cord-015369-72cjogxz 1063 6 recurrent recurrent JJ cord-015369-72cjogxz 1063 7 hernias hernia NNS cord-015369-72cjogxz 1063 8 at at IN cord-015369-72cjogxz 1063 9 the the DT cord-015369-72cjogxz 1063 10 site site NN cord-015369-72cjogxz 1063 11 of of IN cord-015369-72cjogxz 1063 12 infection infection NN cord-015369-72cjogxz 1063 13 . . . cord-015369-72cjogxz 1064 1 Conclusions conclusion NNS cord-015369-72cjogxz 1064 2 . . . cord-015369-72cjogxz 1065 1 Conservative conservative JJ cord-015369-72cjogxz 1065 2 treatment treatment NN cord-015369-72cjogxz 1065 3 is be VBZ cord-015369-72cjogxz 1065 4 a a DT cord-015369-72cjogxz 1065 5 valid valid JJ cord-015369-72cjogxz 1065 6 option option NN cord-015369-72cjogxz 1065 7 for for IN cord-015369-72cjogxz 1065 8 mesh mesh NN cord-015369-72cjogxz 1065 9 graft graft NN cord-015369-72cjogxz 1065 10 infection infection NN cord-015369-72cjogxz 1065 11 . . . cord-015369-72cjogxz 1066 1 Polyglactin Polyglactin NNP cord-015369-72cjogxz 1066 2 / / SYM cord-015369-72cjogxz 1066 3 polypropylene polypropylene NN cord-015369-72cjogxz 1066 4 mesh mesh NN cord-015369-72cjogxz 1066 5 grafts graft NNS cord-015369-72cjogxz 1066 6 might may MD cord-015369-72cjogxz 1066 7 be be VB cord-015369-72cjogxz 1066 8 preferentially preferentially RB cord-015369-72cjogxz 1066 9 used use VBN cord-015369-72cjogxz 1066 10 for for IN cord-015369-72cjogxz 1066 11 open open JJ cord-015369-72cjogxz 1066 12 hernia hernia NN cord-015369-72cjogxz 1066 13 repair repair NN cord-015369-72cjogxz 1066 14 . . . cord-015369-72cjogxz 1067 1 Hernia Hernia NNP cord-015369-72cjogxz 1067 2 repair repair NN cord-015369-72cjogxz 1067 3 should should MD cord-015369-72cjogxz 1067 4 be be VB cord-015369-72cjogxz 1067 5 preferentially preferentially RB cord-015369-72cjogxz 1067 6 performed perform VBN cord-015369-72cjogxz 1067 7 when when WRB cord-015369-72cjogxz 1067 8 hernias hernia NNS cord-015369-72cjogxz 1067 9 are be VBP cord-015369-72cjogxz 1067 10 still still RB cord-015369-72cjogxz 1067 11 small small JJ cord-015369-72cjogxz 1067 12 and and CC cord-015369-72cjogxz 1067 13 when when WRB cord-015369-72cjogxz 1067 14 high high JJ cord-015369-72cjogxz 1067 15 BMI bmi NN cord-015369-72cjogxz 1067 16 is be VBZ cord-015369-72cjogxz 1067 17 reduced reduce VBN cord-015369-72cjogxz 1067 18 . . . cord-015369-72cjogxz 1068 1 Biomeshes Biomeshes NNP cord-015369-72cjogxz 1068 2 in in IN cord-015369-72cjogxz 1068 3 experimental experimental JJ cord-015369-72cjogxz 1068 4 IPOM IPOM NNP cord-015369-72cjogxz 1068 5 repairan repairan JJ cord-015369-72cjogxz 1068 6 overview overview NN cord-015369-72cjogxz 1068 7 of of IN cord-015369-72cjogxz 1068 8 own own JJ cord-015369-72cjogxz 1068 9 trials trial NNS cord-015369-72cjogxz 1068 10 Background Background NNP cord-015369-72cjogxz 1068 11 . . . cord-015369-72cjogxz 1069 1 Biomeshes Biomeshes NNP cord-015369-72cjogxz 1069 2 ( ( -LRB- cord-015369-72cjogxz 1069 3 BM BM NNP cord-015369-72cjogxz 1069 4 ) ) -RRB- cord-015369-72cjogxz 1069 5 are be VBP cord-015369-72cjogxz 1069 6 a a DT cord-015369-72cjogxz 1069 7 new new JJ cord-015369-72cjogxz 1069 8 family family NN cord-015369-72cjogxz 1069 9 of of IN cord-015369-72cjogxz 1069 10 implants implant NNS cord-015369-72cjogxz 1069 11 designed design VBN cord-015369-72cjogxz 1069 12 for for IN cord-015369-72cjogxz 1069 13 the the DT cord-015369-72cjogxz 1069 14 reinforcement reinforcement NN cord-015369-72cjogxz 1069 15 of of IN cord-015369-72cjogxz 1069 16 ventral ventral JJ cord-015369-72cjogxz 1069 17 hernias hernia NNS cord-015369-72cjogxz 1069 18 . . . cord-015369-72cjogxz 1070 1 Their -PRON- PRP$ cord-015369-72cjogxz 1070 2 use use NN cord-015369-72cjogxz 1070 3 is be VBZ cord-015369-72cjogxz 1070 4 gaining gain VBG cord-015369-72cjogxz 1070 5 widespread widespread JJ cord-015369-72cjogxz 1070 6 attention attention NN cord-015369-72cjogxz 1070 7 in in IN cord-015369-72cjogxz 1070 8 the the DT cord-015369-72cjogxz 1070 9 USA USA NNP cord-015369-72cjogxz 1070 10 and and CC cord-015369-72cjogxz 1070 11 some some DT cord-015369-72cjogxz 1070 12 european european JJ cord-015369-72cjogxz 1070 13 countries country NNS cord-015369-72cjogxz 1070 14 . . . cord-015369-72cjogxz 1071 1 Despite despite IN cord-015369-72cjogxz 1071 2 the the DT cord-015369-72cjogxz 1071 3 recommendation recommendation NN cord-015369-72cjogxz 1071 4 to to TO cord-015369-72cjogxz 1071 5 use use VB cord-015369-72cjogxz 1071 6 them -PRON- PRP cord-015369-72cjogxz 1071 7 specifically specifically RB cord-015369-72cjogxz 1071 8 in in IN cord-015369-72cjogxz 1071 9 contaminated contaminated JJ cord-015369-72cjogxz 1071 10 wound wound NN cord-015369-72cjogxz 1071 11 fields field NNS cord-015369-72cjogxz 1071 12 and and CC cord-015369-72cjogxz 1071 13 giant giant JJ cord-015369-72cjogxz 1071 14 hernias hernia NNS cord-015369-72cjogxz 1071 15 , , , cord-015369-72cjogxz 1071 16 experimental experimental JJ cord-015369-72cjogxz 1071 17 data datum NNS cord-015369-72cjogxz 1071 18 on on IN cord-015369-72cjogxz 1071 19 their -PRON- PRP$ cord-015369-72cjogxz 1071 20 biocompatibility biocompatibility NN cord-015369-72cjogxz 1071 21 and and CC cord-015369-72cjogxz 1071 22 tissue tissue NN cord-015369-72cjogxz 1071 23 integration integration NN cord-015369-72cjogxz 1071 24 is be VBZ cord-015369-72cjogxz 1071 25 still still RB cord-015369-72cjogxz 1071 26 scarce scarce JJ cord-015369-72cjogxz 1071 27 . . . cord-015369-72cjogxz 1072 1 Our -PRON- PRP$ cord-015369-72cjogxz 1072 2 study study NN cord-015369-72cjogxz 1072 3 group group NN cord-015369-72cjogxz 1072 4 has have VBZ cord-015369-72cjogxz 1072 5 investigated investigate VBN cord-015369-72cjogxz 1072 6 several several JJ cord-015369-72cjogxz 1072 7 biomeshes biomeshe NNS cord-015369-72cjogxz 1072 8 and and CC cord-015369-72cjogxz 1072 9 tested test VBD cord-015369-72cjogxz 1072 10 new new JJ cord-015369-72cjogxz 1072 11 methods method NNS cord-015369-72cjogxz 1072 12 to to TO cord-015369-72cjogxz 1072 13 possibly possibly RB cord-015369-72cjogxz 1072 14 enhance enhance VB cord-015369-72cjogxz 1072 15 the the DT cord-015369-72cjogxz 1072 16 tissue tissue NN cord-015369-72cjogxz 1072 17 integration integration NN cord-015369-72cjogxz 1072 18 ( ( -LRB- cord-015369-72cjogxz 1072 19 additional additional JJ cord-015369-72cjogxz 1072 20 perforations perforation NNS cord-015369-72cjogxz 1072 21 ; ; : cord-015369-72cjogxz 1072 22 fibrin fibrin NN cord-015369-72cjogxz 1072 23 sealant sealant NN cord-015369-72cjogxz 1072 24 BM bm NN cord-015369-72cjogxz 1072 25 fixation fixation NN cord-015369-72cjogxz 1072 26 ) ) -RRB- cord-015369-72cjogxz 1072 27 . . . cord-015369-72cjogxz 1073 1 Methods method NNS cord-015369-72cjogxz 1073 2 . . . cord-015369-72cjogxz 1074 1 Porcine porcine JJ cord-015369-72cjogxz 1074 2 small small JJ cord-015369-72cjogxz 1074 3 intestine intestine NN cord-015369-72cjogxz 1074 4 submucosa submucosa NN cord-015369-72cjogxz 1074 5 ( ( -LRB- cord-015369-72cjogxz 1074 6 SIS SIS NNP cord-015369-72cjogxz 1074 7 ) ) -RRB- cord-015369-72cjogxz 1074 8 , , , cord-015369-72cjogxz 1074 9 porcine porcine JJ cord-015369-72cjogxz 1074 10 collagen collagen NN cord-015369-72cjogxz 1074 11 ( ( -LRB- cord-015369-72cjogxz 1074 12 PC pc NN cord-015369-72cjogxz 1074 13 ) ) -RRB- cord-015369-72cjogxz 1074 14 and and CC cord-015369-72cjogxz 1074 15 bovine bovine JJ cord-015369-72cjogxz 1074 16 pericard pericard NN cord-015369-72cjogxz 1074 17 ( ( -LRB- cord-015369-72cjogxz 1074 18 BP BP NNP cord-015369-72cjogxz 1074 19 ) ) -RRB- cord-015369-72cjogxz 1074 20 implants implant NNS cord-015369-72cjogxz 1074 21 have have VBP cord-015369-72cjogxz 1074 22 been be VBN cord-015369-72cjogxz 1074 23 tested test VBN cord-015369-72cjogxz 1074 24 ( ( -LRB- cord-015369-72cjogxz 1074 25 n n NN cord-015369-72cjogxz 1074 26 ¼ ¼ NNP cord-015369-72cjogxz 1074 27 6 6 CD cord-015369-72cjogxz 1074 28 per per IN cord-015369-72cjogxz 1074 29 group group NN cord-015369-72cjogxz 1074 30 ) ) -RRB- cord-015369-72cjogxz 1074 31 in in IN cord-015369-72cjogxz 1074 32 a a DT cord-015369-72cjogxz 1074 33 model model NN cord-015369-72cjogxz 1074 34 of of IN cord-015369-72cjogxz 1074 35 open open JJ cord-015369-72cjogxz 1074 36 IPOM IPOM NNP cord-015369-72cjogxz 1074 37 repair repair NN cord-015369-72cjogxz 1074 38 . . . cord-015369-72cjogxz 1075 1 BM BM NNP cord-015369-72cjogxz 1075 2 were be VBD cord-015369-72cjogxz 1075 3 2 2 CD cord-015369-72cjogxz 1075 4 Â â CD cord-015369-72cjogxz 1075 5 2 2 CD cord-015369-72cjogxz 1075 6 cm cm NNS cord-015369-72cjogxz 1075 7 in in IN cord-015369-72cjogxz 1075 8 size size NN cord-015369-72cjogxz 1075 9 and and CC cord-015369-72cjogxz 1075 10 fixated fixate VBN cord-015369-72cjogxz 1075 11 with with IN cord-015369-72cjogxz 1075 12 4 4 CD cord-015369-72cjogxz 1075 13 non non JJ cord-015369-72cjogxz 1075 14 resorbable resorbable JJ cord-015369-72cjogxz 1075 15 sutures suture NNS cord-015369-72cjogxz 1075 16 ( ( -LRB- cord-015369-72cjogxz 1075 17 Synthofil Synthofil NNP cord-015369-72cjogxz 1075 18 , , , cord-015369-72cjogxz 1075 19 Ethicon Ethicon NNP cord-015369-72cjogxz 1075 20 , , , cord-015369-72cjogxz 1075 21 Germany Germany NNP cord-015369-72cjogxz 1075 22 ) ) -RRB- cord-015369-72cjogxz 1075 23 to to IN cord-015369-72cjogxz 1075 24 the the DT cord-015369-72cjogxz 1075 25 peritoneum peritoneum NN cord-015369-72cjogxz 1075 26 . . . cord-015369-72cjogxz 1076 1 Observation observation NN cord-015369-72cjogxz 1076 2 period period NN cord-015369-72cjogxz 1076 3 was be VBD cord-015369-72cjogxz 1076 4 30 30 CD cord-015369-72cjogxz 1076 5 days day NNS cord-015369-72cjogxz 1076 6 in in IN cord-015369-72cjogxz 1076 7 all all DT cord-015369-72cjogxz 1076 8 groups group NNS cord-015369-72cjogxz 1076 9 . . . cord-015369-72cjogxz 1077 1 Primary primary JJ cord-015369-72cjogxz 1077 2 outcome outcome NN cord-015369-72cjogxz 1077 3 parameters parameter NNS cord-015369-72cjogxz 1077 4 were be VBD cord-015369-72cjogxz 1077 5 adhesion adhesion NN cord-015369-72cjogxz 1077 6 formation formation NN cord-015369-72cjogxz 1077 7 , , , cord-015369-72cjogxz 1077 8 tissue tissue NN cord-015369-72cjogxz 1077 9 integration integration NN cord-015369-72cjogxz 1077 10 and and CC cord-015369-72cjogxz 1077 11 dislocation dislocation NN cord-015369-72cjogxz 1077 12 . . . cord-015369-72cjogxz 1078 1 Foreign foreign JJ cord-015369-72cjogxz 1078 2 body body NN cord-015369-72cjogxz 1078 3 reaction reaction NN cord-015369-72cjogxz 1078 4 was be VBD cord-015369-72cjogxz 1078 5 a a DT cord-015369-72cjogxz 1078 6 secondary secondary JJ cord-015369-72cjogxz 1078 7 outcome outcome NN cord-015369-72cjogxz 1078 8 parameter parameter NN cord-015369-72cjogxz 1078 9 assessed assess VBN cord-015369-72cjogxz 1078 10 in in IN cord-015369-72cjogxz 1078 11 histology histology NN cord-015369-72cjogxz 1078 12 ( ( -LRB- cord-015369-72cjogxz 1078 13 HE HE NNP cord-015369-72cjogxz 1078 14 staining stain VBG cord-015369-72cjogxz 1078 15 ) ) -RRB- cord-015369-72cjogxz 1078 16 . . . cord-015369-72cjogxz 1079 1 Results result NNS cord-015369-72cjogxz 1079 2 . . . cord-015369-72cjogxz 1080 1 SIS SIS NNP cord-015369-72cjogxz 1080 2 , , , cord-015369-72cjogxz 1080 3 PC PC NNP cord-015369-72cjogxz 1080 4 and and CC cord-015369-72cjogxz 1080 5 BP BP NNP cord-015369-72cjogxz 1080 6 showed show VBD cord-015369-72cjogxz 1080 7 controversial controversial JJ cord-015369-72cjogxz 1080 8 results result NNS cord-015369-72cjogxz 1080 9 when when WRB cord-015369-72cjogxz 1080 10 indirectly indirectly RB cord-015369-72cjogxz 1080 11 compared compare VBN cord-015369-72cjogxz 1080 12 with with IN cord-015369-72cjogxz 1080 13 the the DT cord-015369-72cjogxz 1080 14 established establish VBN cord-015369-72cjogxz 1080 15 standards standard NNS cord-015369-72cjogxz 1080 16 of of IN cord-015369-72cjogxz 1080 17 synthetic synthetic JJ cord-015369-72cjogxz 1080 18 meshes mesh NNS cord-015369-72cjogxz 1080 19 in in IN cord-015369-72cjogxz 1080 20 IPOM IPOM NNP cord-015369-72cjogxz 1080 21 repair repair NN cord-015369-72cjogxz 1080 22 . . . cord-015369-72cjogxz 1081 1 Problematic problematic JJ cord-015369-72cjogxz 1081 2 findings finding NNS cord-015369-72cjogxz 1081 3 were be VBD cord-015369-72cjogxz 1081 4 obtained obtain VBN cord-015369-72cjogxz 1081 5 for for IN cord-015369-72cjogxz 1081 6 tissue tissue NN cord-015369-72cjogxz 1081 7 integration integration NN cord-015369-72cjogxz 1081 8 and and CC cord-015369-72cjogxz 1081 9 foreign foreign JJ cord-015369-72cjogxz 1081 10 body body NN cord-015369-72cjogxz 1081 11 reaction reaction NN cord-015369-72cjogxz 1081 12 . . . cord-015369-72cjogxz 1082 1 Conclusions conclusion NNS cord-015369-72cjogxz 1082 2 . . . cord-015369-72cjogxz 1083 1 Different different JJ cord-015369-72cjogxz 1083 2 BM BM NNP cord-015369-72cjogxz 1083 3 differ differ VBP cord-015369-72cjogxz 1083 4 distinctively distinctively RB cord-015369-72cjogxz 1083 5 in in IN cord-015369-72cjogxz 1083 6 terms term NNS cord-015369-72cjogxz 1083 7 of of IN cord-015369-72cjogxz 1083 8 important important JJ cord-015369-72cjogxz 1083 9 outcome outcome NN cord-015369-72cjogxz 1083 10 parameters parameter NNS cord-015369-72cjogxz 1083 11 . . . cord-015369-72cjogxz 1084 1 In in IN cord-015369-72cjogxz 1084 2 our -PRON- PRP$ cord-015369-72cjogxz 1084 3 hands hand NNS cord-015369-72cjogxz 1084 4 they -PRON- PRP cord-015369-72cjogxz 1084 5 were be VBD cord-015369-72cjogxz 1084 6 not not RB cord-015369-72cjogxz 1084 7 superior superior JJ cord-015369-72cjogxz 1084 8 to to IN cord-015369-72cjogxz 1084 9 synthetic synthetic JJ cord-015369-72cjogxz 1084 10 meshes mesh NNS cord-015369-72cjogxz 1084 11 . . . cord-015369-72cjogxz 1085 1 The the DT cord-015369-72cjogxz 1085 2 potential potential NN cord-015369-72cjogxz 1085 3 for for IN cord-015369-72cjogxz 1085 4 improvement improvement NN cord-015369-72cjogxz 1085 5 for for IN cord-015369-72cjogxz 1085 6 the the DT cord-015369-72cjogxz 1085 7 use use NN cord-015369-72cjogxz 1085 8 of of IN cord-015369-72cjogxz 1085 9 BM BM NNP cord-015369-72cjogxz 1085 10 will will MD cord-015369-72cjogxz 1085 11 be be VB cord-015369-72cjogxz 1085 12 presented present VBN cord-015369-72cjogxz 1085 13 by by IN cord-015369-72cjogxz 1085 14 the the DT cord-015369-72cjogxz 1085 15 authors author NNS cord-015369-72cjogxz 1085 16 . . . cord-015369-72cjogxz 1086 1 Mesh mesh NN cord-015369-72cjogxz 1086 2 coating coating NN cord-015369-72cjogxz 1086 3 with with IN cord-015369-72cjogxz 1086 4 vital vital JJ cord-015369-72cjogxz 1086 5 human human JJ cord-015369-72cjogxz 1086 6 amniotic amniotic NN cord-015369-72cjogxz 1086 7 membrane membrane NN cord-015369-72cjogxz 1086 8 reduces reduce VBZ cord-015369-72cjogxz 1086 9 early early JJ cord-015369-72cjogxz 1086 10 adhesion adhesion NN cord-015369-72cjogxz 1086 11 formation formation NN cord-015369-72cjogxz 1086 12 in in IN cord-015369-72cjogxz 1086 13 experimental experimental JJ cord-015369-72cjogxz 1086 14 IPOM IPOM NNP cord-015369-72cjogxz 1086 15 repair repair NN cord-015369-72cjogxz 1086 16 Background background NN cord-015369-72cjogxz 1086 17 . . . cord-015369-72cjogxz 1087 1 The the DT cord-015369-72cjogxz 1087 2 laparoscopic laparoscopic JJ cord-015369-72cjogxz 1087 3 intraabdominal intraabdominal JJ cord-015369-72cjogxz 1087 4 peritoneal peritoneal NN cord-015369-72cjogxz 1087 5 onlay onlay NN cord-015369-72cjogxz 1087 6 mesh mesh NN cord-015369-72cjogxz 1087 7 repair repair NN cord-015369-72cjogxz 1087 8 ( ( -LRB- cord-015369-72cjogxz 1087 9 IPOM IPOM NNP cord-015369-72cjogxz 1087 10 ) ) -RRB- cord-015369-72cjogxz 1087 11 is be VBZ cord-015369-72cjogxz 1087 12 an an DT cord-015369-72cjogxz 1087 13 increasingly increasingly RB cord-015369-72cjogxz 1087 14 popular popular JJ cord-015369-72cjogxz 1087 15 technique technique NN cord-015369-72cjogxz 1087 16 for for IN cord-015369-72cjogxz 1087 17 the the DT cord-015369-72cjogxz 1087 18 repair repair NN cord-015369-72cjogxz 1087 19 of of IN cord-015369-72cjogxz 1087 20 incisional incisional NNP cord-015369-72cjogxz 1087 21 hernias hernia NNS cord-015369-72cjogxz 1087 22 . . . cord-015369-72cjogxz 1088 1 The the DT cord-015369-72cjogxz 1088 2 intraabdominal intraabdominal JJ cord-015369-72cjogxz 1088 3 use use NN cord-015369-72cjogxz 1088 4 of of IN cord-015369-72cjogxz 1088 5 synthetic synthetic JJ cord-015369-72cjogxz 1088 6 meshes mesh NNS cord-015369-72cjogxz 1088 7 cavity cavity NN cord-015369-72cjogxz 1088 8 often often RB cord-015369-72cjogxz 1088 9 leads lead VBZ cord-015369-72cjogxz 1088 10 to to IN cord-015369-72cjogxz 1088 11 adhesions adhesion NNS cord-015369-72cjogxz 1088 12 between between IN cord-015369-72cjogxz 1088 13 bowel bowel NN cord-015369-72cjogxz 1088 14 and and CC cord-015369-72cjogxz 1088 15 the the DT cord-015369-72cjogxz 1088 16 implant implant JJ cord-015369-72cjogxz 1088 17 or or CC cord-015369-72cjogxz 1088 18 fixation fixation NN cord-015369-72cjogxz 1088 19 devices device NNS cord-015369-72cjogxz 1088 20 . . . cord-015369-72cjogxz 1089 1 This this DT cord-015369-72cjogxz 1089 2 study study NN cord-015369-72cjogxz 1089 3 was be VBD cord-015369-72cjogxz 1089 4 designed design VBN cord-015369-72cjogxz 1089 5 to to TO cord-015369-72cjogxz 1089 6 assess assess VB cord-015369-72cjogxz 1089 7 the the DT cord-015369-72cjogxz 1089 8 impact impact NN cord-015369-72cjogxz 1089 9 of of IN cord-015369-72cjogxz 1089 10 vital vital JJ cord-015369-72cjogxz 1089 11 human human JJ cord-015369-72cjogxz 1089 12 amniotic amniotic NN cord-015369-72cjogxz 1089 13 membrane membrane NN cord-015369-72cjogxz 1089 14 ( ( -LRB- cord-015369-72cjogxz 1089 15 HA HA NNP cord-015369-72cjogxz 1089 16 ) ) -RRB- cord-015369-72cjogxz 1089 17 to to TO cord-015369-72cjogxz 1089 18 cover cover VB cord-015369-72cjogxz 1089 19 polypropylene polypropylene NN cord-015369-72cjogxz 1089 20 meshes mesh NNS cord-015369-72cjogxz 1089 21 in in IN cord-015369-72cjogxz 1089 22 order order NN cord-015369-72cjogxz 1089 23 to to TO cord-015369-72cjogxz 1089 24 prevent prevent VB cord-015369-72cjogxz 1089 25 adhesion adhesion NN cord-015369-72cjogxz 1089 26 formation formation NN cord-015369-72cjogxz 1089 27 ( ( -LRB- cord-015369-72cjogxz 1089 28 VitaMesh VitaMesh NNP cord-015369-72cjogxz 1089 29 + + CC cord-015369-72cjogxz 1089 30 , , , cord-015369-72cjogxz 1089 31 VM VM NNP cord-015369-72cjogxz 1089 32 , , , cord-015369-72cjogxz 1089 33 Proxy Proxy NNP cord-015369-72cjogxz 1089 34 Biomedical Biomedical NNP cord-015369-72cjogxz 1089 35 , , , cord-015369-72cjogxz 1089 36 Ireland Ireland NNP cord-015369-72cjogxz 1089 37 ) ) -RRB- cord-015369-72cjogxz 1089 38 in in IN cord-015369-72cjogxz 1089 39 experimental experimental JJ cord-015369-72cjogxz 1089 40 IPOM IPOM NNP cord-015369-72cjogxz 1089 41 repair repair NN cord-015369-72cjogxz 1089 42 . . . cord-015369-72cjogxz 1090 1 Vitality vitality NN cord-015369-72cjogxz 1090 2 of of IN cord-015369-72cjogxz 1090 3 this this DT cord-015369-72cjogxz 1090 4 biomatrix biomatrix NN cord-015369-72cjogxz 1090 5 is be VBZ cord-015369-72cjogxz 1090 6 considered consider VBN cord-015369-72cjogxz 1090 7 to to TO cord-015369-72cjogxz 1090 8 preserve preserve VB cord-015369-72cjogxz 1090 9 its -PRON- PRP$ cord-015369-72cjogxz 1090 10 desired desire VBN cord-015369-72cjogxz 1090 11 physiological physiological JJ cord-015369-72cjogxz 1090 12 characteristics characteristic NNS cord-015369-72cjogxz 1090 13 . . . cord-015369-72cjogxz 1091 1 Avital Avital NNP cord-015369-72cjogxz 1091 2 HA HA NNP cord-015369-72cjogxz 1091 3 has have VBZ cord-015369-72cjogxz 1091 4 been be VBN cord-015369-72cjogxz 1091 5 suggested suggest VBN cord-015369-72cjogxz 1091 6 for for IN cord-015369-72cjogxz 1091 7 this this DT cord-015369-72cjogxz 1091 8 purpose purpose NN cord-015369-72cjogxz 1091 9 by by IN cord-015369-72cjogxz 1091 10 other other JJ cord-015369-72cjogxz 1091 11 study study NN cord-015369-72cjogxz 1091 12 groups group NNS cord-015369-72cjogxz 1091 13 . . . cord-015369-72cjogxz 1092 1 Methods method NNS cord-015369-72cjogxz 1092 2 . . . cord-015369-72cjogxz 1093 1 Thirty thirty CD cord-015369-72cjogxz 1093 2 - - HYPH cord-015369-72cjogxz 1093 3 two two CD cord-015369-72cjogxz 1093 4 rats rat NNS cord-015369-72cjogxz 1093 5 were be VBD cord-015369-72cjogxz 1093 6 assigned assign VBN cord-015369-72cjogxz 1093 7 to to IN cord-015369-72cjogxz 1093 8 the the DT cord-015369-72cjogxz 1093 9 implantation implantation NN cord-015369-72cjogxz 1093 10 of of IN cord-015369-72cjogxz 1093 11 VM VM NNP cord-015369-72cjogxz 1093 12 fixated fixate VBN cord-015369-72cjogxz 1093 13 with with IN cord-015369-72cjogxz 1093 14 4 4 CD cord-015369-72cjogxz 1093 15 non non JJ cord-015369-72cjogxz 1093 16 resorbable resorbable JJ cord-015369-72cjogxz 1093 17 sutures suture NNS cord-015369-72cjogxz 1093 18 ( ( -LRB- cord-015369-72cjogxz 1093 19 Synthofil Synthofil NNP cord-015369-72cjogxz 1093 20 , , , cord-015369-72cjogxz 1093 21 Ethicon Ethicon NNP cord-015369-72cjogxz 1093 22 , , , cord-015369-72cjogxz 1093 23 Germany Germany NNP cord-015369-72cjogxz 1093 24 ) ) -RRB- cord-015369-72cjogxz 1093 25 to to IN cord-015369-72cjogxz 1093 26 the the DT cord-015369-72cjogxz 1093 27 peritoneum peritoneum NN cord-015369-72cjogxz 1093 28 . . . cord-015369-72cjogxz 1094 1 VM VM NNP cord-015369-72cjogxz 1094 2 was be VBD cord-015369-72cjogxz 1094 3 covered cover VBN cord-015369-72cjogxz 1094 4 with with IN cord-015369-72cjogxz 1094 5 with with IN cord-015369-72cjogxz 1094 6 HA HA NNP cord-015369-72cjogxz 1094 7 . . . cord-015369-72cjogxz 1095 1 VM VM NNP cord-015369-72cjogxz 1095 2 was be VBD cord-015369-72cjogxz 1095 3 2 2 CD cord-015369-72cjogxz 1095 4 cm cm NNS cord-015369-72cjogxz 1095 5 in in IN cord-015369-72cjogxz 1095 6 diameter diameter NN cord-015369-72cjogxz 1095 7 and and CC cord-015369-72cjogxz 1095 8 implanted implant VBN cord-015369-72cjogxz 1095 9 in in IN cord-015369-72cjogxz 1095 10 open open JJ cord-015369-72cjogxz 1095 11 IPOM IPOM NNP cord-015369-72cjogxz 1095 12 by by IN cord-015369-72cjogxz 1095 13 a a DT cord-015369-72cjogxz 1095 14 laparatomy laparatomy NN cord-015369-72cjogxz 1095 15 . . . cord-015369-72cjogxz 1096 1 The the DT cord-015369-72cjogxz 1096 2 observation observation NN cord-015369-72cjogxz 1096 3 period period NN cord-015369-72cjogxz 1096 4 was be VBD cord-015369-72cjogxz 1096 5 7 7 CD cord-015369-72cjogxz 1096 6 and and CC cord-015369-72cjogxz 1096 7 17 17 CD cord-015369-72cjogxz 1096 8 days day NNS cord-015369-72cjogxz 1096 9 ( ( -LRB- cord-015369-72cjogxz 1096 10 n n CC cord-015369-72cjogxz 1096 11 ¼ ¼ NNP cord-015369-72cjogxz 1096 12 14/18 14/18 CD cord-015369-72cjogxz 1096 13 ) ) -RRB- cord-015369-72cjogxz 1096 14 . . . cord-015369-72cjogxz 1097 1 Adhesions adhesion NNS cord-015369-72cjogxz 1097 2 were be VBD cord-015369-72cjogxz 1097 3 rated rate VBN cord-015369-72cjogxz 1097 4 with with IN cord-015369-72cjogxz 1097 5 the the DT cord-015369-72cjogxz 1097 6 score score NN cord-015369-72cjogxz 1097 7 by by IN cord-015369-72cjogxz 1097 8 Vandendael Vandendael NNP cord-015369-72cjogxz 1097 9 . . . cord-015369-72cjogxz 1098 1 Histology histology NN cord-015369-72cjogxz 1098 2 was be VBD cord-015369-72cjogxz 1098 3 performed perform VBN cord-015369-72cjogxz 1098 4 . . . cord-015369-72cjogxz 1099 1 Results result NNS cord-015369-72cjogxz 1099 2 . . . cord-015369-72cjogxz 1100 1 HA HA NNP cord-015369-72cjogxz 1100 2 markedly markedly RB cord-015369-72cjogxz 1100 3 reduced reduce VBN cord-015369-72cjogxz 1100 4 adhesions adhesion NNS cord-015369-72cjogxz 1100 5 when when WRB cord-015369-72cjogxz 1100 6 compared compare VBN cord-015369-72cjogxz 1100 7 to to IN cord-015369-72cjogxz 1100 8 a a DT cord-015369-72cjogxz 1100 9 historical historical JJ cord-015369-72cjogxz 1100 10 control control NN cord-015369-72cjogxz 1100 11 group group NN cord-015369-72cjogxz 1100 12 ( ( -LRB- cord-015369-72cjogxz 1100 13 VM VM NNP cord-015369-72cjogxz 1100 14 w/o without IN cord-015369-72cjogxz 1100 15 coating coating NN cord-015369-72cjogxz 1100 16 ) ) -RRB- cord-015369-72cjogxz 1100 17 . . . cord-015369-72cjogxz 1101 1 Adhesions adhesion NNS cord-015369-72cjogxz 1101 2 were be VBD cord-015369-72cjogxz 1101 3 found find VBN cord-015369-72cjogxz 1101 4 at at IN cord-015369-72cjogxz 1101 5 structures structure NNS cord-015369-72cjogxz 1101 6 which which WDT cord-015369-72cjogxz 1101 7 were be VBD cord-015369-72cjogxz 1101 8 not not RB cord-015369-72cjogxz 1101 9 fully fully RB cord-015369-72cjogxz 1101 10 covered cover VBN cord-015369-72cjogxz 1101 11 by by IN cord-015369-72cjogxz 1101 12 HA HA NNP cord-015369-72cjogxz 1101 13 ( ( -LRB- cord-015369-72cjogxz 1101 14 protruding protrude VBG cord-015369-72cjogxz 1101 15 sutures suture NNS cord-015369-72cjogxz 1101 16 , , , cord-015369-72cjogxz 1101 17 mesh mesh NN cord-015369-72cjogxz 1101 18 fibers fiber NNS cord-015369-72cjogxz 1101 19 at at IN cord-015369-72cjogxz 1101 20 the the DT cord-015369-72cjogxz 1101 21 edges edge NNS cord-015369-72cjogxz 1101 22 of of IN cord-015369-72cjogxz 1101 23 VM VM NNP cord-015369-72cjogxz 1101 24 ) ) -RRB- cord-015369-72cjogxz 1101 25 . . . cord-015369-72cjogxz 1102 1 HA HA NNP cord-015369-72cjogxz 1102 2 formed form VBD cord-015369-72cjogxz 1102 3 a a DT cord-015369-72cjogxz 1102 4 highly highly RB cord-015369-72cjogxz 1102 5 effective effective JJ cord-015369-72cjogxz 1102 6 barrier barrier NN cord-015369-72cjogxz 1102 7 preventing prevent VBG cord-015369-72cjogxz 1102 8 adhesions adhesion NNS cord-015369-72cjogxz 1102 9 . . . cord-015369-72cjogxz 1103 1 Tissue tissue NN cord-015369-72cjogxz 1103 2 integration integration NN cord-015369-72cjogxz 1103 3 in in IN cord-015369-72cjogxz 1103 4 histology histology NN cord-015369-72cjogxz 1103 5 was be VBD cord-015369-72cjogxz 1103 6 good good JJ cord-015369-72cjogxz 1103 7 . . . cord-015369-72cjogxz 1104 1 Conclusions conclusion NNS cord-015369-72cjogxz 1104 2 . . . cord-015369-72cjogxz 1105 1 Vital vital JJ cord-015369-72cjogxz 1105 2 HA HA NNP cord-015369-72cjogxz 1105 3 yields yield VBZ cord-015369-72cjogxz 1105 4 anti anti JJ cord-015369-72cjogxz 1105 5 - - JJ cord-015369-72cjogxz 1105 6 adhesive adhesive JJ cord-015369-72cjogxz 1105 7 efficacy efficacy NN cord-015369-72cjogxz 1105 8 and and CC cord-015369-72cjogxz 1105 9 showed show VBD cord-015369-72cjogxz 1105 10 good good JJ cord-015369-72cjogxz 1105 11 biocompatibilty biocompatibilty NN cord-015369-72cjogxz 1105 12 in in IN cord-015369-72cjogxz 1105 13 a a DT cord-015369-72cjogxz 1105 14 xeno xeno NNP cord-015369-72cjogxz 1105 15 model model NN cord-015369-72cjogxz 1105 16 . . . cord-015369-72cjogxz 1106 1 Further further JJ cord-015369-72cjogxz 1106 2 research research NN cord-015369-72cjogxz 1106 3 has have VBZ cord-015369-72cjogxz 1106 4 to to TO cord-015369-72cjogxz 1106 5 elucidate elucidate VB cord-015369-72cjogxz 1106 6 a a DT cord-015369-72cjogxz 1106 7 potential potential JJ cord-015369-72cjogxz 1106 8 clinical clinical JJ cord-015369-72cjogxz 1106 9 application application NN cord-015369-72cjogxz 1106 10 . . . cord-015369-72cjogxz 1107 1 Biological biological JJ cord-015369-72cjogxz 1107 2 mesh mesh VBP cord-015369-72cjogxz 1107 3 in in IN cord-015369-72cjogxz 1107 4 complex complex JJ cord-015369-72cjogxz 1107 5 abdominal abdominal JJ cord-015369-72cjogxz 1107 6 wall wall NN cord-015369-72cjogxz 1107 7 repairlong repairlong NNP cord-015369-72cjogxz 1107 8 term term NN cord-015369-72cjogxz 1107 9 results result NNS cord-015369-72cjogxz 1107 10 of of IN cord-015369-72cjogxz 1107 11 use use NN cord-015369-72cjogxz 1107 12 of of IN cord-015369-72cjogxz 1107 13 Permacol Permacol NNP cord-015369-72cjogxz 1107 14 TM TM NNP cord-015369-72cjogxz 1107 15 ( ( -LRB- cord-015369-72cjogxz 1107 16 Porcine Porcine NNP cord-015369-72cjogxz 1107 17 Dermal Dermal NNP cord-015369-72cjogxz 1107 18 Collagen Collagen NNP cord-015369-72cjogxz 1107 19 ) ) -RRB- cord-015369-72cjogxz 1107 20 in in IN cord-015369-72cjogxz 1107 21 a a DT cord-015369-72cjogxz 1107 22 single single JJ cord-015369-72cjogxz 1107 23 institution institution NN cord-015369-72cjogxz 1107 24 R. R. NNP cord-015369-72cjogxz 1107 25 D. D. NNP cord-015369-72cjogxz 1107 26 Pullan Pullan NNP cord-015369-72cjogxz 1107 27 , , , cord-015369-72cjogxz 1107 28 D. D. NNP cord-015369-72cjogxz 1107 29 J. J. NNP cord-015369-72cjogxz 1107 30 Devon Devon NNP cord-015369-72cjogxz 1107 31 Torbay Torbay NNP cord-015369-72cjogxz 1107 32 Hospital Hospital NNP cord-015369-72cjogxz 1107 33 , , , cord-015369-72cjogxz 1107 34 Torquay Torquay NNP cord-015369-72cjogxz 1107 35 , , , cord-015369-72cjogxz 1107 36 UK UK NNP cord-015369-72cjogxz 1107 37 Background Background NNP cord-015369-72cjogxz 1107 38 . . . cord-015369-72cjogxz 1108 1 Abdominal abdominal JJ cord-015369-72cjogxz 1108 2 wall wall NN cord-015369-72cjogxz 1108 3 repair repair NN cord-015369-72cjogxz 1108 4 ( ( -LRB- cord-015369-72cjogxz 1108 5 AWR AWR NNP cord-015369-72cjogxz 1108 6 ) ) -RRB- cord-015369-72cjogxz 1109 1 if if IN cord-015369-72cjogxz 1109 2 poor poor JJ cord-015369-72cjogxz 1109 3 tissues tissue NNS cord-015369-72cjogxz 1109 4 , , , cord-015369-72cjogxz 1109 5 contamination contamination NN cord-015369-72cjogxz 1109 6 , , , cord-015369-72cjogxz 1109 7 intestinal intestinal JJ cord-015369-72cjogxz 1109 8 fistula fistula NN cord-015369-72cjogxz 1109 9 , , , cord-015369-72cjogxz 1109 10 anastomosis anastomosis NN cord-015369-72cjogxz 1109 11 , , , cord-015369-72cjogxz 1109 12 stoma stoma NN cord-015369-72cjogxz 1109 13 and and CC cord-015369-72cjogxz 1109 14 mesh mesh NN cord-015369-72cjogxz 1109 15 impingement impingement NN cord-015369-72cjogxz 1109 16 on on IN cord-015369-72cjogxz 1109 17 bowel bowel NN cord-015369-72cjogxz 1109 18 represent represent VBP cord-015369-72cjogxz 1109 19 formidable formidable JJ cord-015369-72cjogxz 1109 20 surgical surgical JJ cord-015369-72cjogxz 1109 21 challenges challenge NNS cord-015369-72cjogxz 1109 22 . . . cord-015369-72cjogxz 1110 1 Synthetic synthetic JJ cord-015369-72cjogxz 1110 2 mesh mesh NN cord-015369-72cjogxz 1110 3 or or CC cord-015369-72cjogxz 1110 4 suture suture NN cord-015369-72cjogxz 1110 5 repair repair NN cord-015369-72cjogxz 1110 6 is be VBZ cord-015369-72cjogxz 1110 7 inappropriate inappropriate JJ cord-015369-72cjogxz 1110 8 . . . cord-015369-72cjogxz 1111 1 Biological biological JJ cord-015369-72cjogxz 1111 2 meshes mesh NNS cord-015369-72cjogxz 1111 3 are be VBP cord-015369-72cjogxz 1111 4 biocompatible biocompatible JJ cord-015369-72cjogxz 1111 5 , , , cord-015369-72cjogxz 1111 6 offer offer VBP cord-015369-72cjogxz 1111 7 resistance resistance NN cord-015369-72cjogxz 1111 8 to to IN cord-015369-72cjogxz 1111 9 contamination contamination NN cord-015369-72cjogxz 1111 10 , , , cord-015369-72cjogxz 1111 11 minimal minimal JJ cord-015369-72cjogxz 1111 12 adhesion adhesion NN cord-015369-72cjogxz 1111 13 or or CC cord-015369-72cjogxz 1111 14 fistula fistula NN cord-015369-72cjogxz 1111 15 formation formation NN cord-015369-72cjogxz 1111 16 but but CC cord-015369-72cjogxz 1111 17 retain retain VB cord-015369-72cjogxz 1111 18 strength strength NN cord-015369-72cjogxz 1111 19 . . . cord-015369-72cjogxz 1112 1 We -PRON- PRP cord-015369-72cjogxz 1112 2 use use VBP cord-015369-72cjogxz 1112 3 Permacol Permacol NNP cord-015369-72cjogxz 1112 4 TM TM NNP cord-015369-72cjogxz 1112 5 -crosslinked -crosslinked CD cord-015369-72cjogxz 1112 6 porcine porcine JJ cord-015369-72cjogxz 1112 7 dermal dermal JJ cord-015369-72cjogxz 1112 8 collagen collagen NN cord-015369-72cjogxz 1112 9 -in -in : cord-015369-72cjogxz 1112 10 these these DT cord-015369-72cjogxz 1112 11 cases case NNS cord-015369-72cjogxz 1112 12 and and CC cord-015369-72cjogxz 1112 13 present present JJ cord-015369-72cjogxz 1112 14 data datum NNS cord-015369-72cjogxz 1112 15 with with IN cord-015369-72cjogxz 1112 16 long long JJ cord-015369-72cjogxz 1112 17 follow follow VB cord-015369-72cjogxz 1112 18 up up RP cord-015369-72cjogxz 1112 19 . . . cord-015369-72cjogxz 1113 1 Methods method NNS cord-015369-72cjogxz 1113 2 . . . cord-015369-72cjogxz 1114 1 Retrospective retrospective JJ cord-015369-72cjogxz 1114 2 review review NN cord-015369-72cjogxz 1114 3 of of IN cord-015369-72cjogxz 1114 4 patients patient NNS cord-015369-72cjogxz 1114 5 treated treat VBN cord-015369-72cjogxz 1114 6 with with IN cord-015369-72cjogxz 1114 7 Permacol Permacol NNP cord-015369-72cjogxz 1114 8 TM TM NNP cord-015369-72cjogxz 1114 9 for for IN cord-015369-72cjogxz 1114 10 : : : cord-015369-72cjogxz 1114 11 1 1 CD cord-015369-72cjogxz 1114 12 . . . cord-015369-72cjogxz 1115 1 recurrent recurrent JJ cord-015369-72cjogxz 1115 2 incisional incisional JJ cord-015369-72cjogxz 1115 3 hernia hernia NN cord-015369-72cjogxz 1115 4 AE AE NNP cord-015369-72cjogxz 1115 5 mesh mesh NN cord-015369-72cjogxz 1115 6 ; ; : cord-015369-72cjogxz 1115 7 2 2 LS cord-015369-72cjogxz 1115 8 . . . cord-015369-72cjogxz 1115 9 post post NNP cord-015369-72cjogxz 1115 10 laparostomy laparostomy NNP cord-015369-72cjogxz 1115 11 ; ; . cord-015369-72cjogxz 1116 1 3 3 LS cord-015369-72cjogxz 1116 2 . . . cord-015369-72cjogxz 1117 1 enterocutaneous enterocutaneous JJ cord-015369-72cjogxz 1117 2 fistula fistula NN cord-015369-72cjogxz 1117 3 ; ; : cord-015369-72cjogxz 1117 4 4 4 CD cord-015369-72cjogxz 1117 5 . . . cord-015369-72cjogxz 1118 1 contamination contamination NN cord-015369-72cjogxz 1118 2 by by IN cord-015369-72cjogxz 1118 3 anastomosis anastomosis NN cord-015369-72cjogxz 1118 4 ; ; : cord-015369-72cjogxz 1118 5 5 5 CD cord-015369-72cjogxz 1118 6 . . . cord-015369-72cjogxz 1119 1 parastomal parastomal NNP cord-015369-72cjogxz 1119 2 hernia hernia NNP cord-015369-72cjogxz 1119 3 . . . cord-015369-72cjogxz 1120 1 Results result NNS cord-015369-72cjogxz 1120 2 . . . cord-015369-72cjogxz 1121 1 Twenty twenty CD cord-015369-72cjogxz 1121 2 - - HYPH cord-015369-72cjogxz 1121 3 nine nine CD cord-015369-72cjogxz 1121 4 patients patient NNS cord-015369-72cjogxz 1121 5 were be VBD cord-015369-72cjogxz 1121 6 identified identify VBN cord-015369-72cjogxz 1121 7 . . . cord-015369-72cjogxz 1122 1 19 19 CD cord-015369-72cjogxz 1122 2 with with IN cord-015369-72cjogxz 1122 3 acute acute JJ cord-015369-72cjogxz 1122 4 or or CC cord-015369-72cjogxz 1122 5 chronic chronic JJ cord-015369-72cjogxz 1122 6 abdominal abdominal JJ cord-015369-72cjogxz 1122 7 defects defect NNS cord-015369-72cjogxz 1122 8 ; ; : cord-015369-72cjogxz 1122 9 10 10 CD cord-015369-72cjogxz 1122 10 with with IN cord-015369-72cjogxz 1122 11 parastomal parastomal NNP cord-015369-72cjogxz 1122 12 hernia hernia NN cord-015369-72cjogxz 1122 13 . . . cord-015369-72cjogxz 1123 1 Defects defect NNS cord-015369-72cjogxz 1123 2 sizes size NNS cord-015369-72cjogxz 1123 3 from from IN cord-015369-72cjogxz 1123 4 80 80 CD cord-015369-72cjogxz 1123 5 to to TO cord-015369-72cjogxz 1123 6 200 200 CD cord-015369-72cjogxz 1123 7 cm cm NNS cord-015369-72cjogxz 1123 8 2 2 CD cord-015369-72cjogxz 1123 9 . . . cord-015369-72cjogxz 1124 1 Median median JJ cord-015369-72cjogxz 1124 2 age age NN cord-015369-72cjogxz 1124 3 56 56 CD cord-015369-72cjogxz 1125 1 ( ( -LRB- cord-015369-72cjogxz 1125 2 range range NNP cord-015369-72cjogxz 1125 3 28 28 CD cord-015369-72cjogxz 1125 4 - - SYM cord-015369-72cjogxz 1125 5 84 84 CD cord-015369-72cjogxz 1125 6 ) ) -RRB- cord-015369-72cjogxz 1125 7 years year NNS cord-015369-72cjogxz 1125 8 and and CC cord-015369-72cjogxz 1125 9 follow follow VB cord-015369-72cjogxz 1125 10 up up RP cord-015369-72cjogxz 1125 11 51 51 CD cord-015369-72cjogxz 1125 12 ( ( -LRB- cord-015369-72cjogxz 1125 13 36 36 CD cord-015369-72cjogxz 1125 14 - - SYM cord-015369-72cjogxz 1125 15 67 67 CD cord-015369-72cjogxz 1125 16 ) ) -RRB- cord-015369-72cjogxz 1125 17 months month NNS cord-015369-72cjogxz 1125 18 . . . cord-015369-72cjogxz 1126 1 Eleven eleven CD cord-015369-72cjogxz 1126 2 cases case NNS cord-015369-72cjogxz 1126 3 AWR AWR NNP cord-015369-72cjogxz 1126 4 -4 -4 ADD cord-015369-72cjogxz 1127 1 with with IN cord-015369-72cjogxz 1127 2 anastomosis anastomosis NN cord-015369-72cjogxz 1127 3 , , , cord-015369-72cjogxz 1127 4 1 1 CD cord-015369-72cjogxz 1127 5 paracolostomy paracolostomy NN cord-015369-72cjogxz 1127 6 hernia hernia NN cord-015369-72cjogxz 1127 7 . . . cord-015369-72cjogxz 1128 1 Eight eight CD cord-015369-72cjogxz 1128 2 enterocutaneous enterocutaneous JJ cord-015369-72cjogxz 1128 3 fistula fistula NN cord-015369-72cjogxz 1128 4 with with IN cord-015369-72cjogxz 1128 5 deficient deficient JJ cord-015369-72cjogxz 1128 6 abdominal abdominal JJ cord-015369-72cjogxz 1128 7 wall wall NN cord-015369-72cjogxz 1128 8 ; ; : cord-015369-72cjogxz 1128 9 3 3 CD cord-015369-72cjogxz 1128 10 with with IN cord-015369-72cjogxz 1128 11 fistula fistula NN cord-015369-72cjogxz 1128 12 associated associate VBN cord-015369-72cjogxz 1128 13 with with IN cord-015369-72cjogxz 1128 14 mesh mesh NN cord-015369-72cjogxz 1128 15 , , , cord-015369-72cjogxz 1128 16 all all RB cord-015369-72cjogxz 1128 17 with with IN cord-015369-72cjogxz 1128 18 anastomosis anastomosis NN cord-015369-72cjogxz 1128 19 . . . cord-015369-72cjogxz 1129 1 Four four CD cord-015369-72cjogxz 1129 2 recurrent recurrent NN cord-015369-72cjogxz 1129 3 of of IN cord-015369-72cjogxz 1129 4 10 10 CD cord-015369-72cjogxz 1129 5 parastomal parastomal NN cord-015369-72cjogxz 1129 6 hernias hernia NNS cord-015369-72cjogxz 1129 7 . . . cord-015369-72cjogxz 1130 1 Repairs repair NNS cord-015369-72cjogxz 1130 2 by by IN cord-015369-72cjogxz 1130 3 onlay onlay NN cord-015369-72cjogxz 1130 4 , , , cord-015369-72cjogxz 1130 5 inlay inlay NN cord-015369-72cjogxz 1130 6 and and CC cord-015369-72cjogxz 1130 7 sublay sublay NN cord-015369-72cjogxz 1130 8 . . . cord-015369-72cjogxz 1131 1 Sixteen sixteen CD cord-015369-72cjogxz 1131 2 cases case NNS cord-015369-72cjogxz 1131 3 had have VBD cord-015369-72cjogxz 1131 4 no no DT cord-015369-72cjogxz 1131 5 complications complication NNS cord-015369-72cjogxz 1131 6 . . . cord-015369-72cjogxz 1132 1 Major major JJ cord-015369-72cjogxz 1132 2 complications complication NNS cord-015369-72cjogxz 1132 3 in in IN cord-015369-72cjogxz 1132 4 6 6 CD cord-015369-72cjogxz 1132 5 patients patient NNS cord-015369-72cjogxz 1132 6 -2 -2 JJR cord-015369-72cjogxz 1132 7 early early JJ cord-015369-72cjogxz 1132 8 deaths death NNS cord-015369-72cjogxz 1132 9 ( ( -LRB- cord-015369-72cjogxz 1132 10 myocardial myocardial NNP cord-015369-72cjogxz 1132 11 infarct infarct NN cord-015369-72cjogxz 1132 12 and and CC cord-015369-72cjogxz 1132 13 multiorgan multiorgan NNP cord-015369-72cjogxz 1132 14 failure failure NN cord-015369-72cjogxz 1132 15 ) ) -RRB- cord-015369-72cjogxz 1132 16 ; ; : cord-015369-72cjogxz 1132 17 2 2 CD cord-015369-72cjogxz 1132 18 recurrent recurrent JJ cord-015369-72cjogxz 1132 19 hernia hernia NN cord-015369-72cjogxz 1132 20 , , , cord-015369-72cjogxz 1132 21 1 1 CD cord-015369-72cjogxz 1132 22 colonic colonic JJ cord-015369-72cjogxz 1132 23 ischaemia ischaemia NN cord-015369-72cjogxz 1132 24 requiring require VBG cord-015369-72cjogxz 1132 25 relaparotomy relaparotomy NN cord-015369-72cjogxz 1132 26 and and CC cord-015369-72cjogxz 1132 27 1 1 CD cord-015369-72cjogxz 1132 28 intra intra JJ cord-015369-72cjogxz 1132 29 abdominal abdominal JJ cord-015369-72cjogxz 1132 30 abscess abscess NN cord-015369-72cjogxz 1132 31 requiring require VBG cord-015369-72cjogxz 1132 32 percutane percutane NNP cord-015369-72cjogxz 1132 33 - - HYPH cord-015369-72cjogxz 1132 34 ous ous JJ cord-015369-72cjogxz 1132 35 drainage drainage NN cord-015369-72cjogxz 1132 36 . . . cord-015369-72cjogxz 1133 1 Seven seven CD cord-015369-72cjogxz 1133 2 minor minor JJ cord-015369-72cjogxz 1133 3 complications complication NNS cord-015369-72cjogxz 1133 4 comprised comprise VBD cord-015369-72cjogxz 1133 5 4 4 CD cord-015369-72cjogxz 1133 6 wound wound NN cord-015369-72cjogxz 1133 7 infections infection NNS cord-015369-72cjogxz 1133 8 , , , cord-015369-72cjogxz 1133 9 1 1 CD cord-015369-72cjogxz 1133 10 sinus sinus NN cord-015369-72cjogxz 1133 11 and and CC cord-015369-72cjogxz 1133 12 2 2 CD cord-015369-72cjogxz 1133 13 seroma seroma NNS cord-015369-72cjogxz 1133 14 . . . cord-015369-72cjogxz 1134 1 There there EX cord-015369-72cjogxz 1134 2 were be VBD cord-015369-72cjogxz 1134 3 no no DT cord-015369-72cjogxz 1134 4 mesh mesh NN cord-015369-72cjogxz 1134 5 rejections rejection NNS cord-015369-72cjogxz 1134 6 and and CC cord-015369-72cjogxz 1134 7 no no DT cord-015369-72cjogxz 1134 8 further further JJ cord-015369-72cjogxz 1134 9 complications complication NNS cord-015369-72cjogxz 1134 10 . . . cord-015369-72cjogxz 1135 1 Conclusions conclusion NNS cord-015369-72cjogxz 1135 2 . . . cord-015369-72cjogxz 1136 1 In in IN cord-015369-72cjogxz 1136 2 difficult difficult JJ cord-015369-72cjogxz 1136 3 anterior anterior JJ cord-015369-72cjogxz 1136 4 abdominal abdominal JJ cord-015369-72cjogxz 1136 5 wall wall NN cord-015369-72cjogxz 1136 6 repair repair NN cord-015369-72cjogxz 1136 7 Permacol Permacol NNP cord-015369-72cjogxz 1136 8 TM TM NNP cord-015369-72cjogxz 1136 9 is be VBZ cord-015369-72cjogxz 1136 10 effective effective JJ cord-015369-72cjogxz 1136 11 , , , cord-015369-72cjogxz 1136 12 biocompatible biocompatible JJ cord-015369-72cjogxz 1136 13 , , , cord-015369-72cjogxz 1136 14 resistant resistant JJ cord-015369-72cjogxz 1136 15 to to IN cord-015369-72cjogxz 1136 16 infection infection NN cord-015369-72cjogxz 1136 17 , , , cord-015369-72cjogxz 1136 18 contamination contamination NN cord-015369-72cjogxz 1136 19 and and CC cord-015369-72cjogxz 1136 20 can can MD cord-015369-72cjogxz 1136 21 sit sit VB cord-015369-72cjogxz 1136 22 in in IN cord-015369-72cjogxz 1136 23 contact contact NN cord-015369-72cjogxz 1136 24 with with IN cord-015369-72cjogxz 1136 25 bowel bowel NN cord-015369-72cjogxz 1136 26 . . . cord-015369-72cjogxz 1137 1 Background background NN cord-015369-72cjogxz 1137 2 . . . cord-015369-72cjogxz 1138 1 Rectoanal rectoanal JJ cord-015369-72cjogxz 1138 2 repair repair NN cord-015369-72cjogxz 1138 3 ( ( -LRB- cord-015369-72cjogxz 1138 4 RAR RAR NNP cord-015369-72cjogxz 1138 5 ) ) -RRB- cord-015369-72cjogxz 1138 6 , , , cord-015369-72cjogxz 1138 7 a a DT cord-015369-72cjogxz 1138 8 combination combination NN cord-015369-72cjogxz 1138 9 of of IN cord-015369-72cjogxz 1138 10 mucopexy mucopexy NNP cord-015369-72cjogxz 1138 11 and and CC cord-015369-72cjogxz 1138 12 haemorrhoidal haemorrhoidal NN cord-015369-72cjogxz 1138 13 artery artery NN cord-015369-72cjogxz 1138 14 ligation ligation NN cord-015369-72cjogxz 1138 15 ( ( -LRB- cord-015369-72cjogxz 1138 16 HAL HAL NNP cord-015369-72cjogxz 1138 17 ) ) -RRB- cord-015369-72cjogxz 1138 18 , , , cord-015369-72cjogxz 1138 19 is be VBZ cord-015369-72cjogxz 1138 20 proposed propose VBN cord-015369-72cjogxz 1138 21 an an DT cord-015369-72cjogxz 1138 22 ' ' `` cord-015369-72cjogxz 1138 23 ' ' `` cord-015369-72cjogxz 1138 24 anorectal anorectal JJ cord-015369-72cjogxz 1138 25 lifting lifting NN cord-015369-72cjogxz 1138 26 ' ' '' cord-015369-72cjogxz 1138 27 ' ' '' cord-015369-72cjogxz 1138 28 alternative alternative NN cord-015369-72cjogxz 1138 29 to to IN cord-015369-72cjogxz 1138 30 stapled staple VBN cord-015369-72cjogxz 1138 31 haemorrhoidopexy haemorrhoidopexy NN cord-015369-72cjogxz 1138 32 . . . cord-015369-72cjogxz 1139 1 We -PRON- PRP cord-015369-72cjogxz 1139 2 retrospectively retrospectively RB cord-015369-72cjogxz 1139 3 investigated investigate VBD cord-015369-72cjogxz 1139 4 efficacy efficacy NN cord-015369-72cjogxz 1139 5 and and CC cord-015369-72cjogxz 1139 6 safety safety NN cord-015369-72cjogxz 1139 7 for for IN cord-015369-72cjogxz 1139 8 this this DT cord-015369-72cjogxz 1139 9 technique technique NN cord-015369-72cjogxz 1139 10 in in IN cord-015369-72cjogxz 1139 11 our -PRON- PRP$ cord-015369-72cjogxz 1139 12 center center NN cord-015369-72cjogxz 1139 13 . . . cord-015369-72cjogxz 1140 1 Methods method NNS cord-015369-72cjogxz 1140 2 . . . cord-015369-72cjogxz 1141 1 RAR RAR NNP cord-015369-72cjogxz 1141 2 was be VBD cord-015369-72cjogxz 1141 3 performed perform VBN cord-015369-72cjogxz 1141 4 under under IN cord-015369-72cjogxz 1141 5 general general JJ cord-015369-72cjogxz 1141 6 anaesthesia anaesthesia NN cord-015369-72cjogxz 1141 7 in in IN cord-015369-72cjogxz 1141 8 32 32 CD cord-015369-72cjogxz 1141 9 patients patient NNS cord-015369-72cjogxz 1141 10 ( ( -LRB- cord-015369-72cjogxz 1141 11 5 5 CD cord-015369-72cjogxz 1141 12 female female JJ cord-015369-72cjogxz 1141 13 , , , cord-015369-72cjogxz 1141 14 27 27 CD cord-015369-72cjogxz 1141 15 male male JJ cord-015369-72cjogxz 1141 16 ) ) -RRB- cord-015369-72cjogxz 1141 17 with with IN cord-015369-72cjogxz 1141 18 symptomatic symptomatic JJ cord-015369-72cjogxz 1141 19 haemorrhoids haemorrhoid NNS cord-015369-72cjogxz 1141 20 III III NNP cord-015369-72cjogxz 1141 21 ( ( -LRB- cord-015369-72cjogxz 1141 22 78 78 CD cord-015369-72cjogxz 1141 23 % % NN cord-015369-72cjogxz 1141 24 ) ) -RRB- cord-015369-72cjogxz 1141 25 or or CC cord-015369-72cjogxz 1141 26 haemorrhoids haemorrhoid NNS cord-015369-72cjogxz 1141 27 II II NNP cord-015369-72cjogxz 1141 28 - - HYPH cord-015369-72cjogxz 1141 29 III III NNP cord-015369-72cjogxz 1141 30 with with IN cord-015369-72cjogxz 1141 31 simultaneous simultaneous JJ cord-015369-72cjogxz 1141 32 mucosal mucosal JJ cord-015369-72cjogxz 1141 33 prolapse prolapse NN cord-015369-72cjogxz 1141 34 ( ( -LRB- cord-015369-72cjogxz 1141 35 22 22 CD cord-015369-72cjogxz 1141 36 % % NN cord-015369-72cjogxz 1141 37 ) ) -RRB- cord-015369-72cjogxz 1141 38 from from IN cord-015369-72cjogxz 1141 39 March March NNP cord-015369-72cjogxz 1141 40 2007 2007 CD cord-015369-72cjogxz 1141 41 to to IN cord-015369-72cjogxz 1141 42 October October NNP cord-015369-72cjogxz 1141 43 2008 2008 CD cord-015369-72cjogxz 1141 44 . . . cord-015369-72cjogxz 1142 1 Previous previous JJ cord-015369-72cjogxz 1142 2 anal anal JJ cord-015369-72cjogxz 1142 3 surgery surgery NN cord-015369-72cjogxz 1142 4 was be VBD cord-015369-72cjogxz 1142 5 recorded record VBN cord-015369-72cjogxz 1142 6 in in IN cord-015369-72cjogxz 1142 7 five five CD cord-015369-72cjogxz 1142 8 patients patient NNS cord-015369-72cjogxz 1142 9 . . . cord-015369-72cjogxz 1143 1 Mucopexy Mucopexy NNP cord-015369-72cjogxz 1143 2 was be VBD cord-015369-72cjogxz 1143 3 performed perform VBN cord-015369-72cjogxz 1143 4 using use VBG cord-015369-72cjogxz 1143 5 a a DT cord-015369-72cjogxz 1143 6 conventional conventional JJ cord-015369-72cjogxz 1143 7 anal anal JJ cord-015369-72cjogxz 1143 8 dilator dilator NN cord-015369-72cjogxz 1143 9 and and CC cord-015369-72cjogxz 1143 10 Vicryl Vicryl NNP cord-015369-72cjogxz 1143 11 2 2 CD cord-015369-72cjogxz 1143 12 - - SYM cord-015369-72cjogxz 1143 13 0 0 CD cord-015369-72cjogxz 1143 14 absorbable absorbable JJ cord-015369-72cjogxz 1143 15 sutures suture NNS cord-015369-72cjogxz 1143 16 at at IN cord-015369-72cjogxz 1143 17 the the DT cord-015369-72cjogxz 1143 18 prolapse prolapse NN cord-015369-72cjogxz 1143 19 sites site NNS cord-015369-72cjogxz 1143 20 ( ( -LRB- cord-015369-72cjogxz 1143 21 median median JJ cord-015369-72cjogxz 1143 22 3 3 CD cord-015369-72cjogxz 1143 23 , , , cord-015369-72cjogxz 1143 24 range range NN cord-015369-72cjogxz 1143 25 1 1 CD cord-015369-72cjogxz 1143 26 - - SYM cord-015369-72cjogxz 1143 27 4 4 CD cord-015369-72cjogxz 1143 28 , , , cord-015369-72cjogxz 1143 29 sutures suture NNS cord-015369-72cjogxz 1143 30 ) ) -RRB- cord-015369-72cjogxz 1143 31 with with IN cord-015369-72cjogxz 1143 32 secondary secondary JJ cord-015369-72cjogxz 1143 33 HAL HAL NNP cord-015369-72cjogxz 1143 34 ( ( -LRB- cord-015369-72cjogxz 1143 35 median median NN cord-015369-72cjogxz 1143 36 4 4 CD cord-015369-72cjogxz 1143 37 , , , cord-015369-72cjogxz 1143 38 range1 range1 NN cord-015369-72cjogxz 1143 39 - - HYPH cord-015369-72cjogxz 1143 40 6 6 CD cord-015369-72cjogxz 1143 41 ) ) -RRB- cord-015369-72cjogxz 1143 42 according accord VBG cord-015369-72cjogxz 1143 43 to to IN cord-015369-72cjogxz 1143 44 the the DT cord-015369-72cjogxz 1143 45 arterial arterial JJ cord-015369-72cjogxz 1143 46 signal signal NN cord-015369-72cjogxz 1143 47 detected detect VBN cord-015369-72cjogxz 1143 48 by by IN cord-015369-72cjogxz 1143 49 a a DT cord-015369-72cjogxz 1143 50 commercial commercial JJ cord-015369-72cjogxz 1143 51 ultrasound ultrasound NN cord-015369-72cjogxz 1143 52 device device NN cord-015369-72cjogxz 1143 53 . . . cord-015369-72cjogxz 1144 1 All all DT cord-015369-72cjogxz 1144 2 patients patient NNS cord-015369-72cjogxz 1144 3 were be VBD cord-015369-72cjogxz 1144 4 discharged discharge VBN cord-015369-72cjogxz 1144 5 on on IN cord-015369-72cjogxz 1144 6 postoperative postoperative JJ cord-015369-72cjogxz 1144 7 day day NN cord-015369-72cjogxz 1144 8 2 2 CD cord-015369-72cjogxz 1144 9 with with IN cord-015369-72cjogxz 1144 10 stool stool NN cord-015369-72cjogxz 1144 11 softeners softener NNS cord-015369-72cjogxz 1144 12 and and CC cord-015369-72cjogxz 1144 13 pain pain NN cord-015369-72cjogxz 1144 14 medication medication NN cord-015369-72cjogxz 1144 15 on on IN cord-015369-72cjogxz 1144 16 demand demand NN cord-015369-72cjogxz 1144 17 . . . cord-015369-72cjogxz 1145 1 Median median JJ cord-015369-72cjogxz 1145 2 follow follow VBP cord-015369-72cjogxz 1145 3 up up RP cord-015369-72cjogxz 1145 4 was be VBD cord-015369-72cjogxz 1145 5 22 22 CD cord-015369-72cjogxz 1145 6 weeks week NNS cord-015369-72cjogxz 1146 1 ( ( -LRB- cord-015369-72cjogxz 1146 2 range range NNP cord-015369-72cjogxz 1146 3 7 7 CD cord-015369-72cjogxz 1146 4 - - SYM cord-015369-72cjogxz 1146 5 38 38 CD cord-015369-72cjogxz 1146 6 ) ) -RRB- cord-015369-72cjogxz 1146 7 . . . cord-015369-72cjogxz 1147 1 Results result NNS cord-015369-72cjogxz 1147 2 . . . cord-015369-72cjogxz 1148 1 The the DT cord-015369-72cjogxz 1148 2 most most RBS cord-015369-72cjogxz 1148 3 common common JJ cord-015369-72cjogxz 1148 4 adverse adverse JJ cord-015369-72cjogxz 1148 5 event event NN cord-015369-72cjogxz 1148 6 was be VBD cord-015369-72cjogxz 1148 7 pain pain NN cord-015369-72cjogxz 1148 8 in in IN cord-015369-72cjogxz 1148 9 the the DT cord-015369-72cjogxz 1148 10 first first JJ cord-015369-72cjogxz 1148 11 postoperative postoperative JJ cord-015369-72cjogxz 1148 12 month month NN cord-015369-72cjogxz 1148 13 , , , cord-015369-72cjogxz 1148 14 but but CC cord-015369-72cjogxz 1148 15 no no DT cord-015369-72cjogxz 1148 16 severe severe JJ cord-015369-72cjogxz 1148 17 bleeding bleed VBG cord-015369-72cjogxz 1148 18 complication complication NN cord-015369-72cjogxz 1148 19 was be VBD cord-015369-72cjogxz 1148 20 reported report VBN cord-015369-72cjogxz 1148 21 . . . cord-015369-72cjogxz 1149 1 Persisting persist VBG cord-015369-72cjogxz 1149 2 pain pain NN cord-015369-72cjogxz 1149 3 due due IN cord-015369-72cjogxz 1149 4 to to IN cord-015369-72cjogxz 1149 5 perianal perianal JJ cord-015369-72cjogxz 1149 6 thrombosis thrombosis NN cord-015369-72cjogxz 1149 7 was be VBD cord-015369-72cjogxz 1149 8 observed observe VBN cord-015369-72cjogxz 1149 9 in in IN cord-015369-72cjogxz 1149 10 six six CD cord-015369-72cjogxz 1149 11 patients patient NNS cord-015369-72cjogxz 1149 12 ( ( -LRB- cord-015369-72cjogxz 1149 13 19 19 CD cord-015369-72cjogxz 1149 14 % % NN cord-015369-72cjogxz 1149 15 ) ) -RRB- cord-015369-72cjogxz 1149 16 . . . cord-015369-72cjogxz 1150 1 Two two CD cord-015369-72cjogxz 1150 2 patients patient NNS cord-015369-72cjogxz 1150 3 ( ( -LRB- cord-015369-72cjogxz 1150 4 6 6 CD cord-015369-72cjogxz 1150 5 % % NN cord-015369-72cjogxz 1150 6 ) ) -RRB- cord-015369-72cjogxz 1150 7 showed show VBD cord-015369-72cjogxz 1150 8 residual residual JJ cord-015369-72cjogxz 1150 9 haemorrhoids haemorrhoid NNS cord-015369-72cjogxz 1150 10 II II NNP cord-015369-72cjogxz 1150 11 , , , cord-015369-72cjogxz 1150 12 one one CD cord-015369-72cjogxz 1150 13 requiring require VBG cord-015369-72cjogxz 1150 14 further further JJ cord-015369-72cjogxz 1150 15 intervention intervention NN cord-015369-72cjogxz 1150 16 ( ( -LRB- cord-015369-72cjogxz 1150 17 rubber rubber NN cord-015369-72cjogxz 1150 18 band band NN cord-015369-72cjogxz 1150 19 ligation ligation NN cord-015369-72cjogxz 1150 20 ) ) -RRB- cord-015369-72cjogxz 1150 21 . . . cord-015369-72cjogxz 1151 1 In in IN cord-015369-72cjogxz 1151 2 eight eight CD cord-015369-72cjogxz 1151 3 patients patient NNS cord-015369-72cjogxz 1151 4 ( ( -LRB- cord-015369-72cjogxz 1151 5 25 25 CD cord-015369-72cjogxz 1151 6 % % NN cord-015369-72cjogxz 1151 7 ) ) -RRB- cord-015369-72cjogxz 1151 8 marginally marginally RB cord-015369-72cjogxz 1151 9 hyperptrophied hyperptrophie VBN cord-015369-72cjogxz 1151 10 but but CC cord-015369-72cjogxz 1151 11 asymptomatic asymptomatic JJ cord-015369-72cjogxz 1151 12 haemorrhoidal haemorrhoidal NN cord-015369-72cjogxz 1151 13 piles pile NNS cord-015369-72cjogxz 1151 14 were be VBD cord-015369-72cjogxz 1151 15 still still RB cord-015369-72cjogxz 1151 16 visible visible JJ cord-015369-72cjogxz 1151 17 . . . cord-015369-72cjogxz 1152 1 Fecal fecal JJ cord-015369-72cjogxz 1152 2 continence continence NN cord-015369-72cjogxz 1152 3 did do VBD cord-015369-72cjogxz 1152 4 not not RB cord-015369-72cjogxz 1152 5 deteriorate deteriorate VB cord-015369-72cjogxz 1152 6 postoperatively postoperatively RB cord-015369-72cjogxz 1152 7 . . . cord-015369-72cjogxz 1153 1 Conclusions conclusion NNS cord-015369-72cjogxz 1153 2 . . . cord-015369-72cjogxz 1154 1 Rectoanal rectoanal JJ cord-015369-72cjogxz 1154 2 lifting lifting NN cord-015369-72cjogxz 1154 3 is be VBZ cord-015369-72cjogxz 1154 4 a a DT cord-015369-72cjogxz 1154 5 safe safe JJ cord-015369-72cjogxz 1154 6 and and CC cord-015369-72cjogxz 1154 7 effective effective JJ cord-015369-72cjogxz 1154 8 and and CC cord-015369-72cjogxz 1154 9 minimally minimally RB cord-015369-72cjogxz 1154 10 invasive invasive JJ cord-015369-72cjogxz 1154 11 technique technique NN cord-015369-72cjogxz 1154 12 for for IN cord-015369-72cjogxz 1154 13 haemorrhoids haemorrhoid NNS cord-015369-72cjogxz 1154 14 II II NNP cord-015369-72cjogxz 1154 15 - - HYPH cord-015369-72cjogxz 1154 16 III III NNP cord-015369-72cjogxz 1154 17 with with IN cord-015369-72cjogxz 1154 18 simultaneous simultaneous JJ cord-015369-72cjogxz 1154 19 rectal rectal JJ cord-015369-72cjogxz 1154 20 mucosal mucosal JJ cord-015369-72cjogxz 1154 21 prolapse prolapse NN cord-015369-72cjogxz 1154 22 . . . cord-015369-72cjogxz 1155 1 Future future JJ cord-015369-72cjogxz 1155 2 prospective prospective JJ cord-015369-72cjogxz 1155 3 , , , cord-015369-72cjogxz 1155 4 randomized randomized JJ cord-015369-72cjogxz 1155 5 studies study NNS cord-015369-72cjogxz 1155 6 should should MD cord-015369-72cjogxz 1155 7 investigate investigate VB cord-015369-72cjogxz 1155 8 the the DT cord-015369-72cjogxz 1155 9 particular particular JJ cord-015369-72cjogxz 1155 10 benefit benefit NN cord-015369-72cjogxz 1155 11 of of IN cord-015369-72cjogxz 1155 12 a a DT cord-015369-72cjogxz 1155 13 specially specially RB cord-015369-72cjogxz 1155 14 designed design VBN cord-015369-72cjogxz 1155 15 Doppler Doppler NNP cord-015369-72cjogxz 1155 16 - - HYPH cord-015369-72cjogxz 1155 17 guided guide VBN cord-015369-72cjogxz 1155 18 proctoscope proctoscope NN cord-015369-72cjogxz 1155 19 in in IN cord-015369-72cjogxz 1155 20 RAR RAR NNP cord-015369-72cjogxz 1155 21 . . . cord-015369-72cjogxz 1156 1 Therapie Therapie NNP cord-015369-72cjogxz 1156 2 der der NNP cord-015369-72cjogxz 1156 3 komplizierten komplizierten NNP cord-015369-72cjogxz 1156 4 rektovaginalen rektovaginalen NNP cord-015369-72cjogxz 1157 1 Fistel fistel NN cord-015369-72cjogxz 1157 2 mittels mittel NNS cord-015369-72cjogxz 1157 3 modifizierter modifizierter NN cord-015369-72cjogxz 1157 4 Martiusplastik Martiusplastik NNP cord-015369-72cjogxz 1157 5 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1157 6 . . . cord-015369-72cjogxz 1158 1 Insgesamt Insgesamt NNP cord-015369-72cjogxz 1158 2 traten traten NNP cord-015369-72cjogxz 1158 3 10 10 CD cord-015369-72cjogxz 1158 4 ( ( -LRB- cord-015369-72cjogxz 1158 5 0,25 0,25 CD cord-015369-72cjogxz 1158 6 % % NN cord-015369-72cjogxz 1158 7 ) ) -RRB- cord-015369-72cjogxz 1159 1 Infektionen Infektionen NNP cord-015369-72cjogxz 1159 2 auf auf NNP cord-015369-72cjogxz 1159 3 . . . cord-015369-72cjogxz 1159 4 6 6 CD cord-015369-72cjogxz 1159 5 ( ( -LRB- cord-015369-72cjogxz 1159 6 0,15 0,15 CD cord-015369-72cjogxz 1159 7 % % NN cord-015369-72cjogxz 1159 8 ) ) -RRB- cord-015369-72cjogxz 1160 1 dieser dieser NNP cord-015369-72cjogxz 1160 2 Infektion Infektion NNP cord-015369-72cjogxz 1160 3 waren waren NNP cord-015369-72cjogxz 1160 4 rein rein NN cord-015369-72cjogxz 1161 1 oberflächlich oberflächlich NNP cord-015369-72cjogxz 1161 2 die die VBP cord-015369-72cjogxz 1161 3 Haut Haut NNP cord-015369-72cjogxz 1161 4 betreffend betreffend NNP cord-015369-72cjogxz 1161 5 , , , cord-015369-72cjogxz 1161 6 ohne ohne NNP cord-015369-72cjogxz 1161 7 dass dass NNP cord-015369-72cjogxz 1161 8 eine eine NNP cord-015369-72cjogxz 1161 9 weitere weitere NNP cord-015369-72cjogxz 1161 10 chirurgische chirurgische NNP cord-015369-72cjogxz 1161 11 Intervention Intervention NNP cord-015369-72cjogxz 1161 12 nötig nötig JJ cord-015369-72cjogxz 1161 13 war war NN cord-015369-72cjogxz 1161 14 . . . cord-015369-72cjogxz 1162 1 In in IN cord-015369-72cjogxz 1162 2 4 4 CD cord-015369-72cjogxz 1162 3 ( ( -LRB- cord-015369-72cjogxz 1162 4 0,1 0,1 CD cord-015369-72cjogxz 1162 5 % % NN cord-015369-72cjogxz 1162 6 ) ) -RRB- cord-015369-72cjogxz 1163 1 Fällen Fällen NNP cord-015369-72cjogxz 1163 2 kam kam NNP cord-015369-72cjogxz 1163 3 es es XX cord-015369-72cjogxz 1163 4 zu zu NNP cord-015369-72cjogxz 1164 1 einer einer NNP cord-015369-72cjogxz 1164 2 tiefen tiefen NNP cord-015369-72cjogxz 1164 3 den den NNP cord-015369-72cjogxz 1164 4 Patch Patch NNP cord-015369-72cjogxz 1164 5 ( ( -LRB- cord-015369-72cjogxz 1164 6 Dacron Dacron NNP cord-015369-72cjogxz 1164 7 3 3 CD cord-015369-72cjogxz 1164 8 , , , cord-015369-72cjogxz 1165 1 Polyurethan Polyurethan NNP cord-015369-72cjogxz 1165 2 1 1 CD cord-015369-72cjogxz 1165 3 ) ) -RRB- cord-015369-72cjogxz 1165 4 betreffenden betreffenden JJ cord-015369-72cjogxz 1165 5 Infektion Infektion NNP cord-015369-72cjogxz 1165 6 . . . cord-015369-72cjogxz 1166 1 Die die VB cord-015369-72cjogxz 1166 2 tiefen tiefen NNP cord-015369-72cjogxz 1167 1 Infektionen Infektionen NNP cord-015369-72cjogxz 1167 2 traten traten NNP cord-015369-72cjogxz 1167 3 in in IN cord-015369-72cjogxz 1167 4 einem einem NNP cord-015369-72cjogxz 1167 5 Zeitraum Zeitraum NNP cord-015369-72cjogxz 1167 6 von von NNP cord-015369-72cjogxz 1167 7 1 1 CD cord-015369-72cjogxz 1167 8 Monat Monat NNP cord-015369-72cjogxz 1167 9 bis bis NNP cord-015369-72cjogxz 1167 10 6 6 CD cord-015369-72cjogxz 1167 11 Jahre Jahre NNP cord-015369-72cjogxz 1167 12 nach nach NNP cord-015369-72cjogxz 1167 13 der der NNP cord-015369-72cjogxz 1167 14 primären primären NNP cord-015369-72cjogxz 1167 15 Operation Operation NNP cord-015369-72cjogxz 1167 16 auf auf NNP cord-015369-72cjogxz 1167 17 . . . cord-015369-72cjogxz 1168 1 In in IN cord-015369-72cjogxz 1168 2 allen allen NNP cord-015369-72cjogxz 1168 3 Fällen Fällen NNP cord-015369-72cjogxz 1168 4 wurde wurde VBD cord-015369-72cjogxz 1168 5 eine eine NNP cord-015369-72cjogxz 1168 6 Explantation Explantation NNP cord-015369-72cjogxz 1168 7 des des FW cord-015369-72cjogxz 1168 8 Kunststoff Kunststoff NNP cord-015369-72cjogxz 1168 9 - - HYPH cord-015369-72cjogxz 1168 10 Patches Patches NNP cord-015369-72cjogxz 1168 11 durchgefü durchgefü NNP cord-015369-72cjogxz 1168 12 hrt hrt NNP cord-015369-72cjogxz 1168 13 und und IN cord-015369-72cjogxz 1168 14 dieser dieser NNP cord-015369-72cjogxz 1168 15 durch durch NNP cord-015369-72cjogxz 1168 16 einen einen NNP cord-015369-72cjogxz 1168 17 Venen Venen NNP cord-015369-72cjogxz 1168 18 - - HYPH cord-015369-72cjogxz 1168 19 Patch Patch NNP cord-015369-72cjogxz 1168 20 ersetzt ersetzt VBN cord-015369-72cjogxz 1168 21 . . . cord-015369-72cjogxz 1169 1 Bei Bei NNP cord-015369-72cjogxz 1169 2 diesen diesen NNP cord-015369-72cjogxz 1169 3 Revision Revision NNP cord-015369-72cjogxz 1169 4 traten traten NNP cord-015369-72cjogxz 1169 5 weder weder NNP cord-015369-72cjogxz 1169 6 interoperativ interoperativ NNP cord-015369-72cjogxz 1169 7 noch noch NNP cord-015369-72cjogxz 1169 8 postoperativ postoperativ NNP cord-015369-72cjogxz 1169 9 weitere weitere NNP cord-015369-72cjogxz 1169 10 Komplikationen Komplikationen NNP cord-015369-72cjogxz 1169 11 auf auf NNP cord-015369-72cjogxz 1169 12 . . . cord-015369-72cjogxz 1170 1 Keinerlei Keinerlei NNP cord-015369-72cjogxz 1170 2 Infektionen Infektionen NNP cord-015369-72cjogxz 1170 3 zeigten zeigten XX cord-015369-72cjogxz 1170 4 sich sich NNP cord-015369-72cjogxz 1170 5 in in IN cord-015369-72cjogxz 1170 6 der der NNP cord-015369-72cjogxz 1170 7 Gruppe Gruppe NNP cord-015369-72cjogxz 1170 8 der der NNP cord-015369-72cjogxz 1170 9 Carotiseversionen Carotiseversionen NNP cord-015369-72cjogxz 1170 10 . . . cord-015369-72cjogxz 1171 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1171 2 . . . cord-015369-72cjogxz 1172 1 In in IN cord-015369-72cjogxz 1172 2 der der NN cord-015369-72cjogxz 1172 3 Carotischirurgie Carotischirurgie NNP cord-015369-72cjogxz 1172 4 sind sind NNP cord-015369-72cjogxz 1172 5 Infektionen Infektionen NNP cord-015369-72cjogxz 1172 6 seltene seltene NNP cord-015369-72cjogxz 1172 7 Komplikationen Komplikationen NNP cord-015369-72cjogxz 1172 8 . . . cord-015369-72cjogxz 1173 1 Infektionen Infektionen NNP cord-015369-72cjogxz 1173 2 traten traten NNP cord-015369-72cjogxz 1173 3 bei bei NNP cord-015369-72cjogxz 1173 4 uns uns NNP cord-015369-72cjogxz 1173 5 ausschließlich ausschließlich NNS cord-015369-72cjogxz 1173 6 bei bei NNP cord-015369-72cjogxz 1173 7 Operationen Operationen NNP cord-015369-72cjogxz 1173 8 mit mit VBD cord-015369-72cjogxz 1173 9 durchgeführter durchgeführter NNP cord-015369-72cjogxz 1173 10 Patchplastik Patchplastik NNP cord-015369-72cjogxz 1173 11 auf auf NNP cord-015369-72cjogxz 1173 12 , , , cord-015369-72cjogxz 1173 13 wobei wobei JJ cord-015369-72cjogxz 1173 14 der der NNP cord-015369-72cjogxz 1173 15 Polyurethan Polyurethan NNP cord-015369-72cjogxz 1173 16 Patch Patch NNP cord-015369-72cjogxz 1173 17 Vorteile Vorteile NNP cord-015369-72cjogxz 1173 18 gegenüber gegenüber NN cord-015369-72cjogxz 1173 19 dem dem NNP cord-015369-72cjogxz 1173 20 Dacron Dacron NNP cord-015369-72cjogxz 1173 21 Patch Patch NNP cord-015369-72cjogxz 1173 22 zu zu NN cord-015369-72cjogxz 1173 23 haben haben NN cord-015369-72cjogxz 1173 24 scheint scheint NNP cord-015369-72cjogxz 1173 25 . . . cord-015369-72cjogxz 1174 1 Standardtherapie Standardtherapie NNP cord-015369-72cjogxz 1174 2 bei bei NNP cord-015369-72cjogxz 1174 3 einer einer NNP cord-015369-72cjogxz 1174 4 Patchinfektion Patchinfektion NNP cord-015369-72cjogxz 1174 5 ist ist NN cord-015369-72cjogxz 1174 6 die die VBP cord-015369-72cjogxz 1175 1 Explantation Explantation NNP cord-015369-72cjogxz 1175 2 und und IN cord-015369-72cjogxz 1175 3 der der NNP cord-015369-72cjogxz 1175 4 Ersatz ersatz JJ cord-015369-72cjogxz 1175 5 durch durch NN cord-015369-72cjogxz 1175 6 einen einen JJ cord-015369-72cjogxz 1175 7 Venen Venen NNP cord-015369-72cjogxz 1175 8 - - HYPH cord-015369-72cjogxz 1175 9 Patch Patch NNP cord-015369-72cjogxz 1175 10 . . . cord-015369-72cjogxz 1176 1 Die die VB cord-015369-72cjogxz 1176 2 Wertigkeit Wertigkeit NNP cord-015369-72cjogxz 1176 3 homologer homologer NN cord-015369-72cjogxz 1176 4 Spendervenen Spendervenen NNP cord-015369-72cjogxz 1176 5 in in IN cord-015369-72cjogxz 1176 6 der der NNP cord-015369-72cjogxz 1176 7 Shuntchirurgie Shuntchirurgie NNP cord-015369-72cjogxz 1176 8 bei bei NNP cord-015369-72cjogxz 1176 9 ausoperierten ausoperierten NNP cord-015369-72cjogxz 1176 10 Dialysepatienten Dialysepatienten NNP cord-015369-72cjogxz 1176 11 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1176 12 . . . cord-015369-72cjogxz 1177 1 Der Der NNP cord-015369-72cjogxz 1177 2 Erhalt Erhalt NNP cord-015369-72cjogxz 1177 3 des des FW cord-015369-72cjogxz 1177 4 gefährdeten gefährdeten NNP cord-015369-72cjogxz 1177 5 Beines Beines NNPS cord-015369-72cjogxz 1177 6 gelang gelang NNP cord-015369-72cjogxz 1177 7 bei bei NNP cord-015369-72cjogxz 1177 8 6 6 CD cord-015369-72cjogxz 1178 1 Patienten Patienten NNP cord-015369-72cjogxz 1178 2 ( ( -LRB- cord-015369-72cjogxz 1178 3 85 85 CD cord-015369-72cjogxz 1178 4 % % NN cord-015369-72cjogxz 1178 5 ) ) -RRB- cord-015369-72cjogxz 1178 6 , , , cord-015369-72cjogxz 1178 7 bei bei NNP cord-015369-72cjogxz 1178 8 5 5 CD cord-015369-72cjogxz 1178 9 konnten konnten NNP cord-015369-72cjogxz 1178 10 durch durch NNP cord-015369-72cjogxz 1178 11 die die NNP cord-015369-72cjogxz 1178 12 Urokinasinfusionen Urokinasinfusionen NNP cord-015369-72cjogxz 1178 13 ursprünglich ursprünglich NN cord-015369-72cjogxz 1178 14 nicht nicht NNP cord-015369-72cjogxz 1178 15 dargestellte dargestellte NNP cord-015369-72cjogxz 1178 16 Gefäße Gefäße NNP cord-015369-72cjogxz 1178 17 zumindest zumindest RB cord-015369-72cjogxz 1178 18 teilweise teilweise RB cord-015369-72cjogxz 1178 19 wiedereröffnet wiedereröffnet NNP cord-015369-72cjogxz 1178 20 werden werden NNP cord-015369-72cjogxz 1178 21 . . . cord-015369-72cjogxz 1179 1 Dadurch Dadurch NNP cord-015369-72cjogxz 1179 2 ergaben ergaben NN cord-015369-72cjogxz 1179 3 sich sich NNP cord-015369-72cjogxz 1179 4 endovaskuläre endovaskuläre NNP cord-015369-72cjogxz 1179 5 Therapieoptionen Therapieoptionen NNP cord-015369-72cjogxz 1179 6 , , , cord-015369-72cjogxz 1179 7 die die VB cord-015369-72cjogxz 1179 8 vor vor NNP cord-015369-72cjogxz 1179 9 Urokinase Urokinase NNP cord-015369-72cjogxz 1179 10 nicht nicht NNP cord-015369-72cjogxz 1179 11 möglich möglich NNP cord-015369-72cjogxz 1179 12 waren waren NNP cord-015369-72cjogxz 1179 13 . . . cord-015369-72cjogxz 1180 1 Lediglich Lediglich NNP cord-015369-72cjogxz 1180 2 bei bei NNP cord-015369-72cjogxz 1180 3 einer einer NNP cord-015369-72cjogxz 1180 4 Patientin Patientin NNP cord-015369-72cjogxz 1180 5 wurde wurde VBD cord-015369-72cjogxz 1180 6 eine eine NNP cord-015369-72cjogxz 1180 7 Unterschenkelamputation Unterschenkelamputation NNP cord-015369-72cjogxz 1180 8 notwendig notwendig NNP cord-015369-72cjogxz 1180 9 . . . cord-015369-72cjogxz 1181 1 Die die VB cord-015369-72cjogxz 1181 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1181 3 bei bei NNP cord-015369-72cjogxz 1181 4 Diabetikern Diabetikern NNP cord-015369-72cjogxz 1182 1 waren waren NNP cord-015369-72cjogxz 1182 2 erwartungsgemäß erwartungsgemäß NNP cord-015369-72cjogxz 1182 3 besser besser NNP cord-015369-72cjogxz 1182 4 . . . cord-015369-72cjogxz 1183 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1183 2 . . . cord-015369-72cjogxz 1184 1 Die die VB cord-015369-72cjogxz 1184 2 systemische systemische NNP cord-015369-72cjogxz 1184 3 Urokinasetherapie Urokinasetherapie NNP cord-015369-72cjogxz 1184 4 stellt stellt NNP cord-015369-72cjogxz 1184 5 für für NNP cord-015369-72cjogxz 1184 6 bisher bisher NNP cord-015369-72cjogxz 1185 1 als als NNP cord-015369-72cjogxz 1185 2 austherapiert austherapiert NNP cord-015369-72cjogxz 1186 1 eingestufte eingestufte NNP cord-015369-72cjogxz 1186 2 Patienten Patienten NNP cord-015369-72cjogxz 1187 1 eine eine NNP cord-015369-72cjogxz 1187 2 erfreuliche erfreuliche NNP cord-015369-72cjogxz 1187 3 zusätzliche zusätzliche NNP cord-015369-72cjogxz 1187 4 Therapieoption Therapieoption NNP cord-015369-72cjogxz 1187 5 dar dar NNP cord-015369-72cjogxz 1187 6 . . . cord-015369-72cjogxz 1188 1 Unsere Unsere NNP cord-015369-72cjogxz 1188 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1188 3 insbesondere insbesondere NNP cord-015369-72cjogxz 1188 4 die die VBP cord-015369-72cjogxz 1189 1 Beinerhaltungsraten Beinerhaltungsraten NNP cord-015369-72cjogxz 1189 2 von von NNP cord-015369-72cjogxz 1189 3 über über NNP cord-015369-72cjogxz 1190 1 80 80 CD cord-015369-72cjogxz 1190 2 % % NN cord-015369-72cjogxz 1190 3 und und RB cord-015369-72cjogxz 1191 1 Komplikationsraten Komplikationsraten NNP cord-015369-72cjogxz 1191 2 sind sind NNP cord-015369-72cjogxz 1191 3 mit mit NNP cord-015369-72cjogxz 1191 4 den den NNP cord-015369-72cjogxz 1191 5 in in IN cord-015369-72cjogxz 1191 6 der der NNP cord-015369-72cjogxz 1191 7 Literatur Literatur NNP cord-015369-72cjogxz 1191 8 beschriebenen beschriebenen NN cord-015369-72cjogxz 1191 9 vergleichbar vergleichbar NNP cord-015369-72cjogxz 1191 10 und und NNP cord-015369-72cjogxz 1191 11 insgesamt insgesamt NNP cord-015369-72cjogxz 1191 12 als als NNP cord-015369-72cjogxz 1191 13 erfreuliche erfreuliche NNP cord-015369-72cjogxz 1191 14 Alternative Alternative NNP cord-015369-72cjogxz 1191 15 zu zu NNP cord-015369-72cjogxz 1191 16 sehen sehen NNP cord-015369-72cjogxz 1191 17 . . . cord-015369-72cjogxz 1192 1 Wir Wir NNP cord-015369-72cjogxz 1192 2 haben haben NNP cord-015369-72cjogxz 1192 3 aber aber NNP cord-015369-72cjogxz 1192 4 auch auch NNP cord-015369-72cjogxz 1192 5 gesehen gesehen NNP cord-015369-72cjogxz 1192 6 , , , cord-015369-72cjogxz 1192 7 dass dass NNP cord-015369-72cjogxz 1192 8 mit mit NNP cord-015369-72cjogxz 1192 9 einer einer NNP cord-015369-72cjogxz 1192 10 solchen solchen NNP cord-015369-72cjogxz 1192 11 , , , cord-015369-72cjogxz 1192 12 , , , cord-015369-72cjogxz 1193 1 Induktionstherapie Induktionstherapie NNP cord-015369-72cjogxz 1193 2 ' ' POS cord-015369-72cjogxz 1193 3 ' ' '' cord-015369-72cjogxz 1193 4 wieder wieder NNP cord-015369-72cjogxz 1193 5 neuen neuen NNP cord-015369-72cjogxz 1194 1 Optionen Optionen NNP cord-015369-72cjogxz 1194 2 einer einer NNP cord-015369-72cjogxz 1194 3 invasiven invasiven NNP cord-015369-72cjogxz 1194 4 Therapie Therapie NNP cord-015369-72cjogxz 1194 5 möglich möglich NNP cord-015369-72cjogxz 1194 6 werden werden NNP cord-015369-72cjogxz 1194 7 . . . cord-015369-72cjogxz 1195 1 Die die VB cord-015369-72cjogxz 1196 1 Vorteile Vorteile NNP cord-015369-72cjogxz 1196 2 der der NNP cord-015369-72cjogxz 1196 3 Urokinasetherapie Urokinasetherapie NNP cord-015369-72cjogxz 1196 4 sind sind NNP cord-015369-72cjogxz 1196 5 in in IN cord-015369-72cjogxz 1196 6 der der FW cord-015369-72cjogxz 1196 7 guten guten NNP cord-015369-72cjogxz 1197 1 Verträglichkeit Verträglichkeit NNP cord-015369-72cjogxz 1197 2 den den NN cord-015369-72cjogxz 1197 3 überschaubaren überschaubaren NNP cord-015369-72cjogxz 1197 4 Kosten Kosten NNP cord-015369-72cjogxz 1197 5 sowie sowie NNP cord-015369-72cjogxz 1197 6 in in IN cord-015369-72cjogxz 1197 7 einer einer NNP cord-015369-72cjogxz 1197 8 Erweiterung Erweiterung NNP cord-015369-72cjogxz 1197 9 der der NN cord-015369-72cjogxz 1197 10 multimodalen multimodalen VBN cord-015369-72cjogxz 1197 11 Gefäßtherapie Gefäßtherapie NNP cord-015369-72cjogxz 1197 12 zu zu NNP cord-015369-72cjogxz 1197 13 sehen sehen NNP cord-015369-72cjogxz 1197 14 . . . cord-015369-72cjogxz 1198 1 Background background NN cord-015369-72cjogxz 1198 2 . . . cord-015369-72cjogxz 1199 1 Pulmonary pulmonary JJ cord-015369-72cjogxz 1199 2 retransplantation retransplantation NN cord-015369-72cjogxz 1199 3 remains remain VBZ cord-015369-72cjogxz 1199 4 the the DT cord-015369-72cjogxz 1199 5 only only JJ cord-015369-72cjogxz 1199 6 therapeutic therapeutic JJ cord-015369-72cjogxz 1199 7 option option NN cord-015369-72cjogxz 1199 8 in in IN cord-015369-72cjogxz 1199 9 some some DT cord-015369-72cjogxz 1199 10 cases case NNS cord-015369-72cjogxz 1199 11 of of IN cord-015369-72cjogxz 1199 12 severe severe JJ cord-015369-72cjogxz 1199 13 primary primary JJ cord-015369-72cjogxz 1199 14 - - HYPH cord-015369-72cjogxz 1199 15 graft graft NN cord-015369-72cjogxz 1199 16 - - HYPH cord-015369-72cjogxz 1199 17 dysfunction dysfunction NN cord-015369-72cjogxz 1199 18 ( ( -LRB- cord-015369-72cjogxz 1199 19 PGD PGD NNP cord-015369-72cjogxz 1199 20 ) ) -RRB- cord-015369-72cjogxz 1199 21 , , , cord-015369-72cjogxz 1199 22 advanced advanced JJ cord-015369-72cjogxz 1199 23 bronchiolitis bronchiolitis NN cord-015369-72cjogxz 1199 24 - - HYPH cord-015369-72cjogxz 1199 25 obliterans obliterans NNP cord-015369-72cjogxz 1199 26 - - HYPH cord-015369-72cjogxz 1199 27 sydrom sydrom NNP cord-015369-72cjogxz 1199 28 ( ( -LRB- cord-015369-72cjogxz 1199 29 BOS BOS NNP cord-015369-72cjogxz 1199 30 ) ) -RRB- cord-015369-72cjogxz 1199 31 as as RB cord-015369-72cjogxz 1199 32 well well RB cord-015369-72cjogxz 1199 33 as as IN cord-015369-72cjogxz 1199 34 in in IN cord-015369-72cjogxz 1199 35 some some DT cord-015369-72cjogxz 1199 36 cases case NNS cord-015369-72cjogxz 1199 37 of of IN cord-015369-72cjogxz 1199 38 severe severe JJ cord-015369-72cjogxz 1199 39 airway airway NN cord-015369-72cjogxz 1199 40 problems problem NNS cord-015369-72cjogxz 1199 41 ( ( -LRB- cord-015369-72cjogxz 1199 42 AWP AWP NNP cord-015369-72cjogxz 1199 43 ) ) -RRB- cord-015369-72cjogxz 1199 44 , , , cord-015369-72cjogxz 1199 45 mainly mainly RB cord-015369-72cjogxz 1199 46 cicatriceal cicatriceal JJ cord-015369-72cjogxz 1199 47 stenosis stenosis NN cord-015369-72cjogxz 1199 48 . . . cord-015369-72cjogxz 1200 1 However however RB cord-015369-72cjogxz 1200 2 its -PRON- PRP$ cord-015369-72cjogxz 1200 3 value value NN cord-015369-72cjogxz 1200 4 has have VBZ cord-015369-72cjogxz 1200 5 been be VBN cord-015369-72cjogxz 1200 6 questioned question VBN cord-015369-72cjogxz 1200 7 due due IN cord-015369-72cjogxz 1200 8 to to IN cord-015369-72cjogxz 1200 9 overall overall JJ cord-015369-72cjogxz 1200 10 scarcity scarcity NN cord-015369-72cjogxz 1200 11 of of IN cord-015369-72cjogxz 1200 12 donor donor NN cord-015369-72cjogxz 1200 13 organs organ NNS cord-015369-72cjogxz 1200 14 and and CC cord-015369-72cjogxz 1200 15 reports report NNS cord-015369-72cjogxz 1200 16 on on IN cord-015369-72cjogxz 1200 17 unsatisfying unsatisfying JJ cord-015369-72cjogxz 1200 18 outcome outcome NN cord-015369-72cjogxz 1200 19 . . . cord-015369-72cjogxz 1201 1 We -PRON- PRP cord-015369-72cjogxz 1201 2 analysed analyse VBD cord-015369-72cjogxz 1201 3 our -PRON- PRP$ cord-015369-72cjogxz 1201 4 institutional institutional JJ cord-015369-72cjogxz 1201 5 experience experience NN cord-015369-72cjogxz 1201 6 with with IN cord-015369-72cjogxz 1201 7 pulmonary pulmonary JJ cord-015369-72cjogxz 1201 8 retransplantation retransplantation NN cord-015369-72cjogxz 1201 9 to to TO cord-015369-72cjogxz 1201 10 evaluate evaluate VB cord-015369-72cjogxz 1201 11 its -PRON- PRP$ cord-015369-72cjogxz 1201 12 value value NN cord-015369-72cjogxz 1201 13 for for IN cord-015369-72cjogxz 1201 14 different different JJ cord-015369-72cjogxz 1201 15 indications indication NNS cord-015369-72cjogxz 1201 16 . . . cord-015369-72cjogxz 1202 1 Methods method NNS cord-015369-72cjogxz 1202 2 . . . cord-015369-72cjogxz 1203 1 We -PRON- PRP cord-015369-72cjogxz 1203 2 retrospectively retrospectively RB cord-015369-72cjogxz 1203 3 analysed analyse VBD cord-015369-72cjogxz 1203 4 all all DT cord-015369-72cjogxz 1203 5 46 46 CD cord-015369-72cjogxz 1203 6 patients patient NNS cord-015369-72cjogxz 1203 7 undergoing undergo VBG cord-015369-72cjogxz 1203 8 retransplantation retransplantation NN cord-015369-72cjogxz 1203 9 out out IN cord-015369-72cjogxz 1203 10 of of IN cord-015369-72cjogxz 1203 11 567 567 CD cord-015369-72cjogxz 1203 12 consecutive consecutive JJ cord-015369-72cjogxz 1203 13 primary primary JJ cord-015369-72cjogxz 1203 14 lung lung NN cord-015369-72cjogxz 1203 15 or or CC cord-015369-72cjogxz 1203 16 heart heart NN cord-015369-72cjogxz 1203 17 - - HYPH cord-015369-72cjogxz 1203 18 lung lung NN cord-015369-72cjogxz 1203 19 transplantations transplantation NNS cord-015369-72cjogxz 1203 20 performed perform VBN cord-015369-72cjogxz 1203 21 in in IN cord-015369-72cjogxz 1203 22 our -PRON- PRP$ cord-015369-72cjogxz 1203 23 department department NN cord-015369-72cjogxz 1203 24 from from IN cord-015369-72cjogxz 1203 25 8/1995 8/1995 CD cord-015369-72cjogxz 1203 26 - - HYPH cord-015369-72cjogxz 1203 27 8/2006 8/2006 CD cord-015369-72cjogxz 1203 28 . . . cord-015369-72cjogxz 1204 1 We -PRON- PRP cord-015369-72cjogxz 1204 2 stratified stratify VBD cord-015369-72cjogxz 1204 3 patients patient NNS cord-015369-72cjogxz 1204 4 according accord VBG cord-015369-72cjogxz 1204 5 to to IN cord-015369-72cjogxz 1204 6 indication indication NN cord-015369-72cjogxz 1204 7 for for IN cord-015369-72cjogxz 1204 8 retransplantation retransplantation NN cord-015369-72cjogxz 1204 9 and and CC cord-015369-72cjogxz 1204 10 analysed analyse VBD cord-015369-72cjogxz 1204 11 the the DT cord-015369-72cjogxz 1204 12 outome outome NN cord-015369-72cjogxz 1204 13 . . . cord-015369-72cjogxz 1205 1 Results result NNS cord-015369-72cjogxz 1205 2 . . . cord-015369-72cjogxz 1206 1 Forty forty CD cord-015369-72cjogxz 1206 2 - - HYPH cord-015369-72cjogxz 1206 3 six six CD cord-015369-72cjogxz 1206 4 patients patient NNS cord-015369-72cjogxz 1206 5 ( ( -LRB- cord-015369-72cjogxz 1206 6 mean mean VB cord-015369-72cjogxz 1206 7 age age NN cord-015369-72cjogxz 1206 8 41 41 CD cord-015369-72cjogxz 1206 9 AE AE NNP cord-015369-72cjogxz 1206 10 16 16 CD cord-015369-72cjogxz 1206 11 years year NNS cord-015369-72cjogxz 1206 12 , , , cord-015369-72cjogxz 1206 13 18 18 CD cord-015369-72cjogxz 1206 14 male male NN cord-015369-72cjogxz 1206 15 , , , cord-015369-72cjogxz 1206 16 28 28 CD cord-015369-72cjogxz 1206 17 female female JJ cord-015369-72cjogxz 1206 18 ) ) -RRB- cord-015369-72cjogxz 1206 19 underwent undergo VBD cord-015369-72cjogxz 1206 20 retransplantation retransplantation NN cord-015369-72cjogxz 1206 21 ( ( -LRB- cord-015369-72cjogxz 1206 22 14 14 CD cord-015369-72cjogxz 1206 23 BLTX BLTX NNP cord-015369-72cjogxz 1206 24 , , , cord-015369-72cjogxz 1206 25 32 32 CD cord-015369-72cjogxz 1206 26 SLTX SLTX NNP cord-015369-72cjogxz 1206 27 ) ) -RRB- cord-015369-72cjogxz 1206 28 for for IN cord-015369-72cjogxz 1206 29 PGD PGD NNP cord-015369-72cjogxz 1206 30 ( ( -LRB- cord-015369-72cjogxz 1206 31 n n NN cord-015369-72cjogxz 1206 32 ¼ ¼ NNP cord-015369-72cjogxz 1206 33 23 23 CD cord-015369-72cjogxz 1206 34 ) ) -RRB- cord-015369-72cjogxz 1206 35 , , , cord-015369-72cjogxz 1206 36 BOS BOS NNP cord-015369-72cjogxz 1206 37 ( ( -LRB- cord-015369-72cjogxz 1206 38 n n NN cord-015369-72cjogxz 1206 39 ¼ ¼ NNP cord-015369-72cjogxz 1206 40 19 19 CD cord-015369-72cjogxz 1206 41 ) ) -RRB- cord-015369-72cjogxz 1206 42 and and CC cord-015369-72cjogxz 1206 43 AWP AWP NNP cord-015369-72cjogxz 1206 44 ( ( -LRB- cord-015369-72cjogxz 1206 45 n n CC cord-015369-72cjogxz 1206 46 ¼ ¼ NNP cord-015369-72cjogxz 1206 47 4 4 CD cord-015369-72cjogxz 1206 48 ) ) -RRB- cord-015369-72cjogxz 1206 49 . . . cord-015369-72cjogxz 1207 1 Mean mean JJ cord-015369-72cjogxz 1207 2 time time NN cord-015369-72cjogxz 1207 3 to to IN cord-015369-72cjogxz 1207 4 retransplantation retransplantation NNP cord-015369-72cjogxz 1207 5 was be VBD cord-015369-72cjogxz 1207 6 26 26 CD cord-015369-72cjogxz 1207 7 AE AE NNP cord-015369-72cjogxz 1207 8 27 27 CD cord-015369-72cjogxz 1207 9 days day NNS cord-015369-72cjogxz 1207 10 in in IN cord-015369-72cjogxz 1207 11 the the DT cord-015369-72cjogxz 1207 12 PGD PGD NNP cord-015369-72cjogxz 1207 13 - - HYPH cord-015369-72cjogxz 1207 14 group group NN cord-015369-72cjogxz 1207 15 , , , cord-015369-72cjogxz 1207 16 1069 1069 CD cord-015369-72cjogxz 1207 17 AE AE NNP cord-015369-72cjogxz 1207 18 757 757 CD cord-015369-72cjogxz 1207 19 days day NNS cord-015369-72cjogxz 1207 20 in in IN cord-015369-72cjogxz 1207 21 the the DT cord-015369-72cjogxz 1207 22 BOS BOS NNP cord-015369-72cjogxz 1207 23 - - HYPH cord-015369-72cjogxz 1207 24 group group NN cord-015369-72cjogxz 1207 25 and and CC cord-015369-72cjogxz 1207 26 220 220 CD cord-015369-72cjogxz 1207 27 AE AE NNP cord-015369-72cjogxz 1207 28 321 321 CD cord-015369-72cjogxz 1207 29 days day NNS cord-015369-72cjogxz 1207 30 in in IN cord-015369-72cjogxz 1207 31 the the DT cord-015369-72cjogxz 1207 32 AWPgroup awpgroup NN cord-015369-72cjogxz 1207 33 . . . cord-015369-72cjogxz 1208 1 Thirty thirty CD cord-015369-72cjogxz 1208 2 days day NNS cord-015369-72cjogxz 1208 3 , , , cord-015369-72cjogxz 1208 4 1-year 1-year CD cord-015369-72cjogxz 1208 5 and and CC cord-015369-72cjogxz 1208 6 5-years 5-years CD cord-015369-72cjogxz 1208 7 - - HYPH cord-015369-72cjogxz 1208 8 survival survival NN cord-015369-72cjogxz 1208 9 after after IN cord-015369-72cjogxz 1208 10 retransplantation retransplantation NN cord-015369-72cjogxz 1208 11 were be VBD cord-015369-72cjogxz 1208 12 52.2 52.2 CD cord-015369-72cjogxz 1208 13 % % NN cord-015369-72cjogxz 1208 14 , , , cord-015369-72cjogxz 1208 15 34.8 34.8 CD cord-015369-72cjogxz 1208 16 and and CC cord-015369-72cjogxz 1208 17 29.0 29.0 CD cord-015369-72cjogxz 1208 18 % % NN cord-015369-72cjogxz 1208 19 in in IN cord-015369-72cjogxz 1208 20 the the DT cord-015369-72cjogxz 1208 21 PGD PGD NNP cord-015369-72cjogxz 1208 22 - - HYPH cord-015369-72cjogxz 1208 23 group group NN cord-015369-72cjogxz 1208 24 and and CC cord-015369-72cjogxz 1208 25 89.2 89.2 CD cord-015369-72cjogxz 1208 26 % % NN cord-015369-72cjogxz 1208 27 , , , cord-015369-72cjogxz 1208 28 72.5 72.5 CD cord-015369-72cjogxz 1208 29 and and CC cord-015369-72cjogxz 1208 30 61.3 61.3 CD cord-015369-72cjogxz 1208 31 % % NN cord-015369-72cjogxz 1208 32 in in IN cord-015369-72cjogxz 1208 33 the the DT cord-015369-72cjogxz 1208 34 BOS BOS NNP cord-015369-72cjogxz 1208 35 - - HYPH cord-015369-72cjogxz 1208 36 group group NN cord-015369-72cjogxz 1208 37 . . . cord-015369-72cjogxz 1209 1 All all DT cord-015369-72cjogxz 1209 2 4 4 CD cord-015369-72cjogxz 1209 3 patients patient NNS cord-015369-72cjogxz 1209 4 in in IN cord-015369-72cjogxz 1209 5 the the DT cord-015369-72cjogxz 1209 6 AWP AWP NNP cord-015369-72cjogxz 1209 7 - - HYPH cord-015369-72cjogxz 1209 8 group group NN cord-015369-72cjogxz 1209 9 are be VBP cord-015369-72cjogxz 1209 10 still still RB cord-015369-72cjogxz 1209 11 alive alive JJ cord-015369-72cjogxz 1209 12 ( ( -LRB- cord-015369-72cjogxz 1210 1 p p NNP cord-015369-72cjogxz 1210 2 BOS BOS NNP cord-015369-72cjogxz 1210 3 / / SYM cord-015369-72cjogxz 1210 4 PGD PGD NNP cord-015369-72cjogxz 1210 5 ¼ ¼ CD cord-015369-72cjogxz 1210 6 0.02 0.02 CD cord-015369-72cjogxz 1210 7 ; ; : cord-015369-72cjogxz 1210 8 p p NNP cord-015369-72cjogxz 1210 9 BOS BOS NNP cord-015369-72cjogxz 1210 10 / / SYM cord-015369-72cjogxz 1210 11 AWP AWP NNP cord-015369-72cjogxz 1210 12 ¼ ¼ CD cord-015369-72cjogxz 1210 13 0.27 0.27 CD cord-015369-72cjogxz 1210 14 ; ; : cord-015369-72cjogxz 1210 15 p p NN cord-015369-72cjogxz 1210 16 PGD PGD NNP cord-015369-72cjogxz 1210 17 / / SYM cord-015369-72cjogxz 1210 18 AWP AWP NNP cord-015369-72cjogxz 1210 19 ¼ ¼ CD cord-015369-72cjogxz 1210 20 0.06 0.06 CD cord-015369-72cjogxz 1210 21 ) ) -RRB- cord-015369-72cjogxz 1210 22 . . . cord-015369-72cjogxz 1211 1 Conclusions conclusion NNS cord-015369-72cjogxz 1211 2 . . . cord-015369-72cjogxz 1212 1 Retransplantation Retransplantation NNP cord-015369-72cjogxz 1212 2 for for IN cord-015369-72cjogxz 1212 3 BOS BOS NNP cord-015369-72cjogxz 1212 4 offers offer VBZ cord-015369-72cjogxz 1212 5 long long JJ cord-015369-72cjogxz 1212 6 - - HYPH cord-015369-72cjogxz 1212 7 term term NN cord-015369-72cjogxz 1212 8 survival survival NN cord-015369-72cjogxz 1212 9 - - HYPH cord-015369-72cjogxz 1212 10 rates rate NNS cord-015369-72cjogxz 1212 11 in in IN cord-015369-72cjogxz 1212 12 the the DT cord-015369-72cjogxz 1212 13 range range NN cord-015369-72cjogxz 1212 14 of of IN cord-015369-72cjogxz 1212 15 primary primary JJ cord-015369-72cjogxz 1212 16 lung lung NN cord-015369-72cjogxz 1212 17 transplantation transplantation NN cord-015369-72cjogxz 1212 18 for for IN cord-015369-72cjogxz 1212 19 selected select VBN cord-015369-72cjogxz 1212 20 patients patient NNS cord-015369-72cjogxz 1212 21 . . . cord-015369-72cjogxz 1213 1 Long long JJ cord-015369-72cjogxz 1213 2 - - HYPH cord-015369-72cjogxz 1213 3 term term NN cord-015369-72cjogxz 1213 4 survival survival NN cord-015369-72cjogxz 1213 5 - - HYPH cord-015369-72cjogxz 1213 6 rates rate NNS cord-015369-72cjogxz 1213 7 for for IN cord-015369-72cjogxz 1213 8 retransplantation retransplantation NN cord-015369-72cjogxz 1213 9 due due IN cord-015369-72cjogxz 1213 10 to to IN cord-015369-72cjogxz 1213 11 PGD PGD NNP cord-015369-72cjogxz 1213 12 are be VBP cord-015369-72cjogxz 1213 13 significantly significantly RB cord-015369-72cjogxz 1213 14 lower low JJR cord-015369-72cjogxz 1213 15 , , , cord-015369-72cjogxz 1213 16 warranting warrant VBG cord-015369-72cjogxz 1213 17 restrictive restrictive JJ cord-015369-72cjogxz 1213 18 use use NN cord-015369-72cjogxz 1213 19 in in IN cord-015369-72cjogxz 1213 20 this this DT cord-015369-72cjogxz 1213 21 indication indication NN cord-015369-72cjogxz 1213 22 . . . cord-015369-72cjogxz 1214 1 In in IN cord-015369-72cjogxz 1214 2 our -PRON- PRP$ cord-015369-72cjogxz 1214 3 experience experience NN cord-015369-72cjogxz 1214 4 with with IN cord-015369-72cjogxz 1214 5 a a DT cord-015369-72cjogxz 1214 6 limited limited JJ cord-015369-72cjogxz 1214 7 number number NN cord-015369-72cjogxz 1214 8 of of IN cord-015369-72cjogxz 1214 9 patients patient NNS cord-015369-72cjogxz 1214 10 , , , cord-015369-72cjogxz 1214 11 retransplantation retransplantation NN cord-015369-72cjogxz 1214 12 for for IN cord-015369-72cjogxz 1214 13 AWP AWP NNP cord-015369-72cjogxz 1214 14 has have VBZ cord-015369-72cjogxz 1214 15 excellent excellent JJ cord-015369-72cjogxz 1214 16 results result NNS cord-015369-72cjogxz 1214 17 . . . cord-015369-72cjogxz 1215 1 Pulmonary pulmonary JJ cord-015369-72cjogxz 1215 2 retransplantation retransplantation NN cord-015369-72cjogxz 1215 3 for for IN cord-015369-72cjogxz 1215 4 chronic chronic JJ cord-015369-72cjogxz 1215 5 problems problem NNS cord-015369-72cjogxz 1215 6 is be VBZ cord-015369-72cjogxz 1215 7 a a DT cord-015369-72cjogxz 1215 8 worthwhile worthwhile JJ cord-015369-72cjogxz 1215 9 effort effort NN cord-015369-72cjogxz 1215 10 , , , cord-015369-72cjogxz 1215 11 provided provide VBN cord-015369-72cjogxz 1215 12 that that IN cord-015369-72cjogxz 1215 13 patients patient NNS cord-015369-72cjogxz 1215 14 are be VBP cord-015369-72cjogxz 1215 15 carefully carefully RB cord-015369-72cjogxz 1215 16 selected select VBN cord-015369-72cjogxz 1215 17 . . . cord-015369-72cjogxz 1216 1 Retransplantation Retransplantation NNP cord-015369-72cjogxz 1216 2 for for IN cord-015369-72cjogxz 1216 3 PGD PGD NNP cord-015369-72cjogxz 1216 4 should should MD cord-015369-72cjogxz 1216 5 be be VB cord-015369-72cjogxz 1216 6 avoided avoid VBN cord-015369-72cjogxz 1216 7 . . . cord-015369-72cjogxz 1217 1 ECMO ECMO NNP cord-015369-72cjogxz 1217 2 support support NN cord-015369-72cjogxz 1217 3 in in IN cord-015369-72cjogxz 1217 4 extended extended JJ cord-015369-72cjogxz 1217 5 thoracic thoracic JJ cord-015369-72cjogxz 1217 6 procedures procedure NNS cord-015369-72cjogxz 1217 7 Background Background NNP cord-015369-72cjogxz 1217 8 . . . cord-015369-72cjogxz 1218 1 For for IN cord-015369-72cjogxz 1218 2 extended extended JJ cord-015369-72cjogxz 1218 3 pulmonary pulmonary JJ cord-015369-72cjogxz 1218 4 resections resection NNS cord-015369-72cjogxz 1218 5 and and CC cord-015369-72cjogxz 1218 6 complex complex JJ cord-015369-72cjogxz 1218 7 tracheo tracheo NN cord-015369-72cjogxz 1218 8 - - HYPH cord-015369-72cjogxz 1218 9 bronchial bronchial JJ cord-015369-72cjogxz 1218 10 reconstructions reconstruction NNS cord-015369-72cjogxz 1218 11 CPB CPB NNP cord-015369-72cjogxz 1218 12 is be VBZ cord-015369-72cjogxz 1218 13 the the DT cord-015369-72cjogxz 1218 14 standard standard JJ cord-015369-72cjogxz 1218 15 way way NN cord-015369-72cjogxz 1218 16 for for IN cord-015369-72cjogxz 1218 17 extended extended JJ cord-015369-72cjogxz 1218 18 cardio cardio JJ cord-015369-72cjogxz 1218 19 - - HYPH cord-015369-72cjogxz 1218 20 respiratory respiratory JJ cord-015369-72cjogxz 1218 21 support support NN cord-015369-72cjogxz 1218 22 . . . cord-015369-72cjogxz 1219 1 Given give VBN cord-015369-72cjogxz 1219 2 the the DT cord-015369-72cjogxz 1219 3 extensive extensive JJ cord-015369-72cjogxz 1219 4 experience experience NN cord-015369-72cjogxz 1219 5 with with IN cord-015369-72cjogxz 1219 6 ECMO ECMO NNP cord-015369-72cjogxz 1219 7 support support NN cord-015369-72cjogxz 1219 8 in in IN cord-015369-72cjogxz 1219 9 lung lung NN cord-015369-72cjogxz 1219 10 transplantation transplantation NN cord-015369-72cjogxz 1219 11 in in IN cord-015369-72cjogxz 1219 12 our -PRON- PRP$ cord-015369-72cjogxz 1219 13 department department NN cord-015369-72cjogxz 1219 14 , , , cord-015369-72cjogxz 1219 15 we -PRON- PRP cord-015369-72cjogxz 1219 16 introduced introduce VBD cord-015369-72cjogxz 1219 17 ECMO ECMO NNP cord-015369-72cjogxz 1219 18 also also RB cord-015369-72cjogxz 1219 19 for for IN cord-015369-72cjogxz 1219 20 selected select VBN cord-015369-72cjogxz 1219 21 cases case NNS cord-015369-72cjogxz 1219 22 of of IN cord-015369-72cjogxz 1219 23 general general JJ cord-015369-72cjogxz 1219 24 thoracic thoracic JJ cord-015369-72cjogxz 1219 25 surgery surgery NN cord-015369-72cjogxz 1219 26 ( ( -LRB- cord-015369-72cjogxz 1219 27 GTS GTS NNP cord-015369-72cjogxz 1219 28 ) ) -RRB- cord-015369-72cjogxz 1219 29 . . . cord-015369-72cjogxz 1220 1 Methods method NNS cord-015369-72cjogxz 1220 2 . . . cord-015369-72cjogxz 1221 1 All all DT cord-015369-72cjogxz 1221 2 patients patient NNS cord-015369-72cjogxz 1221 3 undergoing undergo VBG cord-015369-72cjogxz 1221 4 GTS GTS NNP cord-015369-72cjogxz 1221 5 on on IN cord-015369-72cjogxz 1221 6 ECMO ecmo NN cord-015369-72cjogxz 1221 7 support support NN cord-015369-72cjogxz 1221 8 in in IN cord-015369-72cjogxz 1221 9 our -PRON- PRP$ cord-015369-72cjogxz 1221 10 institution institution NN cord-015369-72cjogxz 1221 11 between between IN cord-015369-72cjogxz 1221 12 May May NNP cord-015369-72cjogxz 1221 13 2001 2001 CD cord-015369-72cjogxz 1221 14 and and CC cord-015369-72cjogxz 1221 15 January January NNP cord-015369-72cjogxz 1221 16 2009 2009 CD cord-015369-72cjogxz 1221 17 . . . cord-015369-72cjogxz 1222 1 Results result NNS cord-015369-72cjogxz 1222 2 . . . cord-015369-72cjogxz 1223 1 Nine nine CD cord-015369-72cjogxz 1223 2 patients patient NNS cord-015369-72cjogxz 1223 3 ( ( -LRB- cord-015369-72cjogxz 1223 4 2 2 CD cord-015369-72cjogxz 1223 5 female female JJ cord-015369-72cjogxz 1223 6 and and CC cord-015369-72cjogxz 1223 7 5 5 CD cord-015369-72cjogxz 1223 8 male male NN cord-015369-72cjogxz 1223 9 with with IN cord-015369-72cjogxz 1223 10 a a DT cord-015369-72cjogxz 1223 11 median median JJ cord-015369-72cjogxz 1223 12 age age NN cord-015369-72cjogxz 1223 13 of of IN cord-015369-72cjogxz 1223 14 55 55 CD cord-015369-72cjogxz 1223 15 years year NNS cord-015369-72cjogxz 1223 16 , , , cord-015369-72cjogxz 1223 17 range range VBP cord-015369-72cjogxz 1223 18 21 21 CD cord-015369-72cjogxz 1223 19 - - SYM cord-015369-72cjogxz 1223 20 68 68 CD cord-015369-72cjogxz 1223 21 ) ) -RRB- cord-015369-72cjogxz 1223 22 underwent undergo VBD cord-015369-72cjogxz 1223 23 extended extended JJ cord-015369-72cjogxz 1223 24 procedures procedure NNS cord-015369-72cjogxz 1223 25 using use VBG cord-015369-72cjogxz 1223 26 ECMO ECMO NNP cord-015369-72cjogxz 1223 27 . . . cord-015369-72cjogxz 1224 1 Both both DT cord-015369-72cjogxz 1224 2 central central JJ cord-015369-72cjogxz 1224 3 ( ( -LRB- cord-015369-72cjogxz 1224 4 n n NN cord-015369-72cjogxz 1224 5 ¼ ¼ NNP cord-015369-72cjogxz 1224 6 4 4 CD cord-015369-72cjogxz 1224 7 ) ) -RRB- cord-015369-72cjogxz 1224 8 and and CC cord-015369-72cjogxz 1224 9 peripheral peripheral JJ cord-015369-72cjogxz 1224 10 ( ( -LRB- cord-015369-72cjogxz 1224 11 n n NN cord-015369-72cjogxz 1224 12 ¼ ¼ NNP cord-015369-72cjogxz 1224 13 5 5 CD cord-015369-72cjogxz 1224 14 ) ) -RRB- cord-015369-72cjogxz 1224 15 cannulation cannulation NN cord-015369-72cjogxz 1224 16 was be VBD cord-015369-72cjogxz 1224 17 used use VBN cord-015369-72cjogxz 1224 18 . . . cord-015369-72cjogxz 1225 1 In in IN cord-015369-72cjogxz 1225 2 two two CD cord-015369-72cjogxz 1225 3 cases case NNS cord-015369-72cjogxz 1225 4 , , , cord-015369-72cjogxz 1225 5 ECMO ECMO NNP cord-015369-72cjogxz 1225 6 was be VBD cord-015369-72cjogxz 1225 7 introduced introduce VBN cord-015369-72cjogxz 1225 8 under under IN cord-015369-72cjogxz 1225 9 emergency emergency NN cord-015369-72cjogxz 1225 10 conditions condition NNS cord-015369-72cjogxz 1225 11 due due JJ cord-015369-72cjogxz 1225 12 to to IN cord-015369-72cjogxz 1225 13 life life NN cord-015369-72cjogxz 1225 14 - - HYPH cord-015369-72cjogxz 1225 15 threatening threaten VBG cord-015369-72cjogxz 1225 16 tracheobronchial tracheobronchial JJ cord-015369-72cjogxz 1225 17 injury injury NN cord-015369-72cjogxz 1225 18 , , , cord-015369-72cjogxz 1225 19 and and CC cord-015369-72cjogxz 1225 20 was be VBD cord-015369-72cjogxz 1225 21 prolonged prolong VBN cord-015369-72cjogxz 1225 22 into into IN cord-015369-72cjogxz 1225 23 the the DT cord-015369-72cjogxz 1225 24 postoperative postoperative JJ cord-015369-72cjogxz 1225 25 period period NN cord-015369-72cjogxz 1225 26 after after IN cord-015369-72cjogxz 1225 27 trachebronchial trachebronchial NNP cord-015369-72cjogxz 1225 28 reconstruction reconstruction NN cord-015369-72cjogxz 1225 29 . . . cord-015369-72cjogxz 1226 1 In in IN cord-015369-72cjogxz 1226 2 seven seven CD cord-015369-72cjogxz 1226 3 cases case NNS cord-015369-72cjogxz 1226 4 the the DT cord-015369-72cjogxz 1226 5 procedure procedure NN cord-015369-72cjogxz 1226 6 was be VBD cord-015369-72cjogxz 1226 7 elective elective JJ cord-015369-72cjogxz 1226 8 for for IN cord-015369-72cjogxz 1226 9 surgery surgery NN cord-015369-72cjogxz 1226 10 of of IN cord-015369-72cjogxz 1226 11 bronchogenic bronchogenic JJ cord-015369-72cjogxz 1226 12 carcinoma carcinoma NN cord-015369-72cjogxz 1226 13 . . . cord-015369-72cjogxz 1227 1 ECMO ECMO NNP cord-015369-72cjogxz 1227 2 bypass bypass NNP cord-015369-72cjogxz 1227 3 was be VBD cord-015369-72cjogxz 1227 4 performed perform VBN cord-015369-72cjogxz 1227 5 for for IN cord-015369-72cjogxz 1227 6 aortal aortal JJ cord-015369-72cjogxz 1227 7 resection resection NNP cord-015369-72cjogxz 1227 8 ( ( -LRB- cord-015369-72cjogxz 1227 9 n n NNP cord-015369-72cjogxz 1227 10 ¼ ¼ NNP cord-015369-72cjogxz 1227 11 1 1 CD cord-015369-72cjogxz 1227 12 ) ) -RRB- cord-015369-72cjogxz 1227 13 , , , cord-015369-72cjogxz 1227 14 for for IN cord-015369-72cjogxz 1227 15 pure pure JJ cord-015369-72cjogxz 1227 16 carinal carinal JJ cord-015369-72cjogxz 1227 17 resection resection NN cord-015369-72cjogxz 1227 18 ( ( -LRB- cord-015369-72cjogxz 1227 19 n n CC cord-015369-72cjogxz 1227 20 ¼ ¼ NNP cord-015369-72cjogxz 1227 21 3 3 CD cord-015369-72cjogxz 1227 22 ) ) -RRB- cord-015369-72cjogxz 1227 23 , , , cord-015369-72cjogxz 1227 24 or or CC cord-015369-72cjogxz 1227 25 in in IN cord-015369-72cjogxz 1227 26 combination combination NN cord-015369-72cjogxz 1227 27 with with IN cord-015369-72cjogxz 1227 28 central central JJ cord-015369-72cjogxz 1227 29 resection resection NN cord-015369-72cjogxz 1227 30 of of IN cord-015369-72cjogxz 1227 31 left left JJ cord-015369-72cjogxz 1227 32 pulmonary pulmonary JJ cord-015369-72cjogxz 1227 33 artery artery NN cord-015369-72cjogxz 1227 34 ( ( -LRB- cord-015369-72cjogxz 1227 35 n n NN cord-015369-72cjogxz 1227 36 ¼ ¼ NNP cord-015369-72cjogxz 1227 37 1 1 CD cord-015369-72cjogxz 1227 38 ) ) -RRB- cord-015369-72cjogxz 1227 39 , , , cord-015369-72cjogxz 1227 40 with with IN cord-015369-72cjogxz 1227 41 reinsertion reinsertion NN cord-015369-72cjogxz 1227 42 of of IN cord-015369-72cjogxz 1227 43 left left JJ cord-015369-72cjogxz 1227 44 main main JJ cord-015369-72cjogxz 1227 45 bronchus bronchus NN cord-015369-72cjogxz 1227 46 to to IN cord-015369-72cjogxz 1227 47 trachea trachea NN cord-015369-72cjogxz 1227 48 ( ( -LRB- cord-015369-72cjogxz 1227 49 n n NN cord-015369-72cjogxz 1227 50 ¼ ¼ NNP cord-015369-72cjogxz 1227 51 1 1 CD cord-015369-72cjogxz 1227 52 ) ) -RRB- cord-015369-72cjogxz 1227 53 , , , cord-015369-72cjogxz 1227 54 and and CC cord-015369-72cjogxz 1227 55 with with IN cord-015369-72cjogxz 1227 56 upper upper JJ cord-015369-72cjogxz 1227 57 bilobectomy bilobectomy NN cord-015369-72cjogxz 1227 58 and and CC cord-015369-72cjogxz 1227 59 reinsertion reinsertion NN cord-015369-72cjogxz 1227 60 of of IN cord-015369-72cjogxz 1227 61 right right JJ cord-015369-72cjogxz 1227 62 lower low JJR cord-015369-72cjogxz 1227 63 lobe lobe NN cord-015369-72cjogxz 1227 64 into into IN cord-015369-72cjogxz 1227 65 the the DT cord-015369-72cjogxz 1227 66 left left JJ cord-015369-72cjogxz 1227 67 main main JJ cord-015369-72cjogxz 1227 68 bronchus bronchus NN cord-015369-72cjogxz 1227 69 ( ( -LRB- cord-015369-72cjogxz 1227 70 n n NN cord-015369-72cjogxz 1227 71 ¼ ¼ NNP cord-015369-72cjogxz 1227 72 1 1 CD cord-015369-72cjogxz 1227 73 ) ) -RRB- cord-015369-72cjogxz 1227 74 . . . cord-015369-72cjogxz 1228 1 No no DT cord-015369-72cjogxz 1228 2 deaths death NNS cord-015369-72cjogxz 1228 3 occurred occur VBD cord-015369-72cjogxz 1228 4 during during IN cord-015369-72cjogxz 1228 5 the the DT cord-015369-72cjogxz 1228 6 first first JJ cord-015369-72cjogxz 1228 7 30 30 CD cord-015369-72cjogxz 1228 8 postoperative postoperative JJ cord-015369-72cjogxz 1228 9 days day NNS cord-015369-72cjogxz 1228 10 . . . cord-015369-72cjogxz 1229 1 Conclusions conclusion NNS cord-015369-72cjogxz 1229 2 . . . cord-015369-72cjogxz 1230 1 This this DT cord-015369-72cjogxz 1230 2 study study NN cord-015369-72cjogxz 1230 3 confirms confirm VBZ cord-015369-72cjogxz 1230 4 the the DT cord-015369-72cjogxz 1230 5 safety safety NN cord-015369-72cjogxz 1230 6 of of IN cord-015369-72cjogxz 1230 7 ECMO ECMO NNP cord-015369-72cjogxz 1230 8 in in IN cord-015369-72cjogxz 1230 9 GTS GTS NNP cord-015369-72cjogxz 1230 10 instead instead RB cord-015369-72cjogxz 1230 11 of of IN cord-015369-72cjogxz 1230 12 CPB CPB NNP cord-015369-72cjogxz 1230 13 . . . cord-015369-72cjogxz 1231 1 Avoiding avoid VBG cord-015369-72cjogxz 1231 2 cross cross JJ cord-015369-72cjogxz 1231 3 - - JJ cord-015369-72cjogxz 1231 4 table table JJ cord-015369-72cjogxz 1231 5 ventilation ventilation NN cord-015369-72cjogxz 1231 6 facilitates facilitate VBZ cord-015369-72cjogxz 1231 7 visibility visibility NN cord-015369-72cjogxz 1231 8 and and CC cord-015369-72cjogxz 1231 9 precision precision NN cord-015369-72cjogxz 1231 10 . . . cord-015369-72cjogxz 1232 1 The the DT cord-015369-72cjogxz 1232 2 closed closed JJ cord-015369-72cjogxz 1232 3 ECMO ecmo NN cord-015369-72cjogxz 1232 4 circuits circuit NNS cord-015369-72cjogxz 1232 5 prevent prevent VBP cord-015369-72cjogxz 1232 6 tumour tumour NN cord-015369-72cjogxz 1232 7 cell cell NN cord-015369-72cjogxz 1232 8 spilling spill VBG cord-015369-72cjogxz 1232 9 from from IN cord-015369-72cjogxz 1232 10 the the DT cord-015369-72cjogxz 1232 11 operating operating NN cord-015369-72cjogxz 1232 12 field field NN cord-015369-72cjogxz 1232 13 . . . cord-015369-72cjogxz 1233 1 Full full JJ cord-015369-72cjogxz 1233 2 heparinisation heparinisation NN cord-015369-72cjogxz 1233 3 can can MD cord-015369-72cjogxz 1233 4 be be VB cord-015369-72cjogxz 1233 5 avoided avoid VBN cord-015369-72cjogxz 1233 6 , , , cord-015369-72cjogxz 1233 7 and and CC cord-015369-72cjogxz 1233 8 bleeding bleed VBG cord-015369-72cjogxz 1233 9 complications complication NNS cord-015369-72cjogxz 1233 10 can can MD cord-015369-72cjogxz 1233 11 be be VB cord-015369-72cjogxz 1233 12 prevented prevent VBN cord-015369-72cjogxz 1233 13 . . . cord-015369-72cjogxz 1234 1 ECMO ECMO NNP cord-015369-72cjogxz 1234 2 support support NN cord-015369-72cjogxz 1234 3 can can MD cord-015369-72cjogxz 1234 4 also also RB cord-015369-72cjogxz 1234 5 be be VB cord-015369-72cjogxz 1234 6 prolonged prolong VBN cord-015369-72cjogxz 1234 7 into into IN cord-015369-72cjogxz 1234 8 the the DT cord-015369-72cjogxz 1234 9 postoperative postoperative JJ cord-015369-72cjogxz 1234 10 period period NN cord-015369-72cjogxz 1234 11 . . . cord-015369-72cjogxz 1235 1 Background background NN cord-015369-72cjogxz 1235 2 . . . cord-015369-72cjogxz 1236 1 The the DT cord-015369-72cjogxz 1236 2 aime aime NN cord-015369-72cjogxz 1236 3 of of IN cord-015369-72cjogxz 1236 4 this this DT cord-015369-72cjogxz 1236 5 retrospective retrospective JJ cord-015369-72cjogxz 1236 6 study study NN cord-015369-72cjogxz 1236 7 is be VBZ cord-015369-72cjogxz 1236 8 to to TO cord-015369-72cjogxz 1236 9 underline underline VB cord-015369-72cjogxz 1236 10 that that IN cord-015369-72cjogxz 1236 11 a a DT cord-015369-72cjogxz 1236 12 surgical surgical JJ cord-015369-72cjogxz 1236 13 tool tool NN cord-015369-72cjogxz 1236 14 respective respective JJ cord-015369-72cjogxz 1236 15 Videothoracocscopy Videothoracocscopy NNP cord-015369-72cjogxz 1236 16 helps help VBZ cord-015369-72cjogxz 1236 17 to to TO cord-015369-72cjogxz 1236 18 find find VB cord-015369-72cjogxz 1236 19 diagnosis diagnosis NN cord-015369-72cjogxz 1236 20 quick quick JJ cord-015369-72cjogxz 1236 21 ! ! . cord-015369-72cjogxz 1237 1 Methods method NNS cord-015369-72cjogxz 1237 2 . . . cord-015369-72cjogxz 1238 1 One one CD cord-015369-72cjogxz 1238 2 hundred hundred CD cord-015369-72cjogxz 1238 3 and and CC cord-015369-72cjogxz 1238 4 ten ten CD cord-015369-72cjogxz 1238 5 patients patient NNS cord-015369-72cjogxz 1238 6 were be VBD cord-015369-72cjogxz 1238 7 included include VBN cord-015369-72cjogxz 1238 8 in in IN cord-015369-72cjogxz 1238 9 the the DT cord-015369-72cjogxz 1238 10 study study NN cord-015369-72cjogxz 1238 11 78 78 CD cord-015369-72cjogxz 1238 12 male male NN cord-015369-72cjogxz 1238 13 and and CC cord-015369-72cjogxz 1238 14 42 42 CD cord-015369-72cjogxz 1238 15 female female JJ cord-015369-72cjogxz 1238 16 , , , cord-015369-72cjogxz 1238 17 mean mean VB cord-015369-72cjogxz 1238 18 age age NN cord-015369-72cjogxz 1238 19 49.7 49.7 CD cord-015369-72cjogxz 1238 20 a a DT cord-015369-72cjogxz 1238 21 ( ( -LRB- cord-015369-72cjogxz 1238 22 range range NN cord-015369-72cjogxz 1238 23 from from IN cord-015369-72cjogxz 1238 24 28 28 CD cord-015369-72cjogxz 1238 25 to to IN cord-015369-72cjogxz 1238 26 91a 91a CD cord-015369-72cjogxz 1238 27 ) ) -RRB- cord-015369-72cjogxz 1238 28 . . . cord-015369-72cjogxz 1239 1 Indication indication NN cord-015369-72cjogxz 1239 2 for for IN cord-015369-72cjogxz 1239 3 inclusion inclusion NN cord-015369-72cjogxz 1239 4 in in IN cord-015369-72cjogxz 1239 5 the the DT cord-015369-72cjogxz 1239 6 study study NN cord-015369-72cjogxz 1239 7 effusion effusion NN cord-015369-72cjogxz 1239 8 under under IN cord-015369-72cjogxz 1239 9 monitoring monitoring NN cord-015369-72cjogxz 1239 10 , , , cord-015369-72cjogxz 1239 11 multiple multiple JJ cord-015369-72cjogxz 1239 12 punction punction NN cord-015369-72cjogxz 1239 13 without without IN cord-015369-72cjogxz 1239 14 any any DT cord-015369-72cjogxz 1239 15 result result NN cord-015369-72cjogxz 1239 16 . . . cord-015369-72cjogxz 1240 1 Causes cause NNS cord-015369-72cjogxz 1240 2 for for IN cord-015369-72cjogxz 1240 3 effusion effusion NN cord-015369-72cjogxz 1240 4 was be VBD cord-015369-72cjogxz 1240 5 in in IN cord-015369-72cjogxz 1240 6 all all DT cord-015369-72cjogxz 1240 7 cases case NNS cord-015369-72cjogxz 1240 8 unknown unknown JJ cord-015369-72cjogxz 1240 9 before before IN cord-015369-72cjogxz 1240 10 intervention intervention NN cord-015369-72cjogxz 1240 11 . . . cord-015369-72cjogxz 1241 1 Patients patient NNS cord-015369-72cjogxz 1241 2 transferred transfer VBN cord-015369-72cjogxz 1241 3 to to IN cord-015369-72cjogxz 1241 4 the the DT cord-015369-72cjogxz 1241 5 surgical surgical JJ cord-015369-72cjogxz 1241 6 unit unit NN cord-015369-72cjogxz 1241 7 for for IN cord-015369-72cjogxz 1241 8 diagnosis diagnosis NN cord-015369-72cjogxz 1241 9 and and CC cord-015369-72cjogxz 1241 10 therapy therapy NN cord-015369-72cjogxz 1241 11 were be VBD cord-015369-72cjogxz 1241 12 origin origin JJ cord-015369-72cjogxz 1241 13 in in IN cord-015369-72cjogxz 1241 14 all all DT cord-015369-72cjogxz 1241 15 cases case NNS cord-015369-72cjogxz 1241 16 from from IN cord-015369-72cjogxz 1241 17 pulmologists pulmologist NNS cord-015369-72cjogxz 1241 18 or or CC cord-015369-72cjogxz 1241 19 conservative conservative JJ cord-015369-72cjogxz 1241 20 departments department NNS cord-015369-72cjogxz 1241 21 . . . cord-015369-72cjogxz 1242 1 Patients patient NNS cord-015369-72cjogxz 1242 2 were be VBD cord-015369-72cjogxz 1242 3 treated treat VBN cord-015369-72cjogxz 1242 4 the the DT cord-015369-72cjogxz 1242 5 day day NN cord-015369-72cjogxz 1242 6 after after IN cord-015369-72cjogxz 1242 7 admission admission NN cord-015369-72cjogxz 1242 8 by by IN cord-015369-72cjogxz 1242 9 videothoracoscopy videothoracoscopy NNP cord-015369-72cjogxz 1242 10 combined combine VBN cord-015369-72cjogxz 1242 11 with with IN cord-015369-72cjogxz 1242 12 sampling sampling NN cord-015369-72cjogxz 1242 13 , , , cord-015369-72cjogxz 1242 14 frozen frozen JJ cord-015369-72cjogxz 1242 15 section section NN cord-015369-72cjogxz 1242 16 and and CC cord-015369-72cjogxz 1242 17 if if IN cord-015369-72cjogxz 1242 18 available available JJ cord-015369-72cjogxz 1242 19 following follow VBG cord-015369-72cjogxz 1242 20 therapy therapy NN cord-015369-72cjogxz 1242 21 immediately immediately RB cord-015369-72cjogxz 1242 22 intraoperative intraoperative JJ cord-015369-72cjogxz 1242 23 or or CC cord-015369-72cjogxz 1242 24 the the DT cord-015369-72cjogxz 1242 25 following follow VBG cord-015369-72cjogxz 1242 26 days day NNS cord-015369-72cjogxz 1242 27 . . . cord-015369-72cjogxz 1243 1 Discharge discharge NN cord-015369-72cjogxz 1243 2 from from IN cord-015369-72cjogxz 1243 3 hospital hospital NN cord-015369-72cjogxz 1243 4 was be VBD cord-015369-72cjogxz 1243 5 done do VBN cord-015369-72cjogxz 1243 6 after after IN cord-015369-72cjogxz 1243 7 removal removal NN cord-015369-72cjogxz 1243 8 of of IN cord-015369-72cjogxz 1243 9 chest chest NN cord-015369-72cjogxz 1243 10 tube tube NN cord-015369-72cjogxz 1243 11 and and CC cord-015369-72cjogxz 1243 12 aftercare aftercare NN cord-015369-72cjogxz 1243 13 was be VBD cord-015369-72cjogxz 1243 14 in in IN cord-015369-72cjogxz 1243 15 the the DT cord-015369-72cjogxz 1243 16 outpatient outpatient NN cord-015369-72cjogxz 1243 17 department department NN cord-015369-72cjogxz 1243 18 . . . cord-015369-72cjogxz 1244 1 Results result NNS cord-015369-72cjogxz 1244 2 . . . cord-015369-72cjogxz 1245 1 Diagnosis diagnosis NN cord-015369-72cjogxz 1245 2 was be VBD cord-015369-72cjogxz 1245 3 possible possible JJ cord-015369-72cjogxz 1245 4 in in IN cord-015369-72cjogxz 1245 5 all all DT cord-015369-72cjogxz 1245 6 cases case NNS cord-015369-72cjogxz 1245 7 , , , cord-015369-72cjogxz 1245 8 the the DT cord-015369-72cjogxz 1245 9 gap gap NN cord-015369-72cjogxz 1245 10 in in IN cord-015369-72cjogxz 1245 11 between between IN cord-015369-72cjogxz 1245 12 admission admission NN cord-015369-72cjogxz 1245 13 on on IN cord-015369-72cjogxz 1245 14 the the DT cord-015369-72cjogxz 1245 15 surgical surgical JJ cord-015369-72cjogxz 1245 16 department department NN cord-015369-72cjogxz 1245 17 and and CC cord-015369-72cjogxz 1245 18 beginning beginning NN cord-015369-72cjogxz 1245 19 of of IN cord-015369-72cjogxz 1245 20 treatment treatment NN cord-015369-72cjogxz 1245 21 range range NN cord-015369-72cjogxz 1245 22 from from IN cord-015369-72cjogxz 1245 23 1 1 CD cord-015369-72cjogxz 1245 24 to to IN cord-015369-72cjogxz 1245 25 32 32 CD cord-015369-72cjogxz 1245 26 days day NNS cord-015369-72cjogxz 1245 27 mean mean VBP cord-015369-72cjogxz 1245 28 2 2 CD cord-015369-72cjogxz 1245 29 days day NNS cord-015369-72cjogxz 1245 30 . . . cord-015369-72cjogxz 1246 1 Gap gap VB cord-015369-72cjogxz 1246 2 in in IN cord-015369-72cjogxz 1246 3 between between IN cord-015369-72cjogxz 1246 4 symptoms symptom NNS cord-015369-72cjogxz 1246 5 , , , cord-015369-72cjogxz 1246 6 multiple multiple JJ cord-015369-72cjogxz 1246 7 punction punction NN cord-015369-72cjogxz 1246 8 and and CC cord-015369-72cjogxz 1246 9 suction suction NN cord-015369-72cjogxz 1246 10 without without IN cord-015369-72cjogxz 1246 11 diagnosis diagnosis NN cord-015369-72cjogxz 1246 12 range range NN cord-015369-72cjogxz 1246 13 from from IN cord-015369-72cjogxz 1246 14 1 1 CD cord-015369-72cjogxz 1246 15 to to IN cord-015369-72cjogxz 1246 16 886 886 CD cord-015369-72cjogxz 1246 17 days day NNS cord-015369-72cjogxz 1246 18 mean mean VBP cord-015369-72cjogxz 1246 19 42.2 42.2 CD cord-015369-72cjogxz 1246 20 days day NNS cord-015369-72cjogxz 1246 21 . . . cord-015369-72cjogxz 1247 1 In in IN cord-015369-72cjogxz 1247 2 comparison comparison NN cord-015369-72cjogxz 1247 3 early early JJ cord-015369-72cjogxz 1247 4 surgical surgical JJ cord-015369-72cjogxz 1247 5 intervention intervention NN cord-015369-72cjogxz 1247 6 as as IN cord-015369-72cjogxz 1247 7 videothoracoscopy videothoracoscopy NNP cord-015369-72cjogxz 1247 8 helps help VBZ cord-015369-72cjogxz 1247 9 to to TO cord-015369-72cjogxz 1247 10 achiev achiev VB cord-015369-72cjogxz 1247 11 quick quick JJ cord-015369-72cjogxz 1247 12 diagnosis diagnosis NN cord-015369-72cjogxz 1247 13 and and CC cord-015369-72cjogxz 1247 14 therapy therapy NN cord-015369-72cjogxz 1247 15 . . . cord-015369-72cjogxz 1248 1 Conclusions conclusion NNS cord-015369-72cjogxz 1248 2 . . . cord-015369-72cjogxz 1249 1 In in IN cord-015369-72cjogxz 1249 2 conclusion conclusion NN cord-015369-72cjogxz 1249 3 we -PRON- PRP cord-015369-72cjogxz 1249 4 emphasize emphasize VBP cord-015369-72cjogxz 1249 5 that that IN cord-015369-72cjogxz 1249 6 early early JJ cord-015369-72cjogxz 1249 7 surgical surgical JJ cord-015369-72cjogxz 1249 8 intervention intervention NN cord-015369-72cjogxz 1249 9 after after IN cord-015369-72cjogxz 1249 10 short short JJ cord-015369-72cjogxz 1249 11 conservative conservative NN cord-015369-72cjogxz 1249 12 try try VB cord-015369-72cjogxz 1249 13 show show VB cord-015369-72cjogxz 1249 14 up up RP cord-015369-72cjogxz 1249 15 with with IN cord-015369-72cjogxz 1249 16 diagnosis diagnosis NN cord-015369-72cjogxz 1249 17 and and CC cord-015369-72cjogxz 1249 18 successful successful JJ cord-015369-72cjogxz 1249 19 therapy therapy NN cord-015369-72cjogxz 1249 20 . . . cord-015369-72cjogxz 1250 1 First first JJ cord-015369-72cjogxz 1250 2 series series NN cord-015369-72cjogxz 1250 3 of of IN cord-015369-72cjogxz 1250 4 robotic robotic JJ cord-015369-72cjogxz 1250 5 pulmonary pulmonary JJ cord-015369-72cjogxz 1250 6 lobectomy lobectomy NN cord-015369-72cjogxz 1250 7 Background Background NNP cord-015369-72cjogxz 1250 8 . . . cord-015369-72cjogxz 1251 1 Surgical surgical JJ cord-015369-72cjogxz 1251 2 resection resection NN cord-015369-72cjogxz 1251 3 is be VBZ cord-015369-72cjogxz 1251 4 the the DT cord-015369-72cjogxz 1251 5 primary primary JJ cord-015369-72cjogxz 1251 6 treatment treatment NN cord-015369-72cjogxz 1251 7 for for IN cord-015369-72cjogxz 1251 8 early early JJ cord-015369-72cjogxz 1251 9 stage stage NN cord-015369-72cjogxz 1251 10 non non JJ cord-015369-72cjogxz 1251 11 - - JJ cord-015369-72cjogxz 1251 12 small small JJ cord-015369-72cjogxz 1251 13 cell cell NN cord-015369-72cjogxz 1251 14 lung lung NN cord-015369-72cjogxz 1251 15 cancer cancer NN cord-015369-72cjogxz 1251 16 ( ( -LRB- cord-015369-72cjogxz 1251 17 NSCLC NSCLC NNP cord-015369-72cjogxz 1251 18 ) ) -RRB- cord-015369-72cjogxz 1251 19 . . . cord-015369-72cjogxz 1252 1 Different different JJ cord-015369-72cjogxz 1252 2 minimally minimally RB cord-015369-72cjogxz 1252 3 invasive invasive JJ cord-015369-72cjogxz 1252 4 approaches approach NNS cord-015369-72cjogxz 1252 5 are be VBP cord-015369-72cjogxz 1252 6 currently currently RB cord-015369-72cjogxz 1252 7 under under IN cord-015369-72cjogxz 1252 8 investigation investigation NN cord-015369-72cjogxz 1252 9 : : : cord-015369-72cjogxz 1253 1 In in IN cord-015369-72cjogxz 1253 2 addition addition NN cord-015369-72cjogxz 1253 3 to to IN cord-015369-72cjogxz 1253 4 conventional conventional JJ cord-015369-72cjogxz 1253 5 video video NN cord-015369-72cjogxz 1253 6 - - HYPH cord-015369-72cjogxz 1253 7 assisted assist VBN cord-015369-72cjogxz 1253 8 thoracoscopic thoracoscopic NN cord-015369-72cjogxz 1253 9 surgery surgery NN cord-015369-72cjogxz 1253 10 ( ( -LRB- cord-015369-72cjogxz 1253 11 VATS vat NNS cord-015369-72cjogxz 1253 12 ) ) -RRB- cord-015369-72cjogxz 1253 13 , , , cord-015369-72cjogxz 1253 14 the the DT cord-015369-72cjogxz 1253 15 robotic robotic JJ cord-015369-72cjogxz 1253 16 technology technology NN cord-015369-72cjogxz 1253 17 with with IN cord-015369-72cjogxz 1253 18 the the DT cord-015369-72cjogxz 1253 19 daVinci daVinci NNP cord-015369-72cjogxz 1253 20 System System NNP cord-015369-72cjogxz 1253 21 has have VBZ cord-015369-72cjogxz 1253 22 emerged emerge VBN cord-015369-72cjogxz 1253 23 over over IN cord-015369-72cjogxz 1253 24 the the DT cord-015369-72cjogxz 1253 25 last last JJ cord-015369-72cjogxz 1253 26 10 10 CD cord-015369-72cjogxz 1253 27 years year NNS cord-015369-72cjogxz 1253 28 . . . cord-015369-72cjogxz 1254 1 Methods method NNS cord-015369-72cjogxz 1254 2 . . . cord-015369-72cjogxz 1255 1 Twenty twenty CD cord-015369-72cjogxz 1255 2 - - HYPH cord-015369-72cjogxz 1255 3 seven seven CD cord-015369-72cjogxz 1255 4 patients patient NNS cord-015369-72cjogxz 1255 5 ( ( -LRB- cord-015369-72cjogxz 1255 6 12 12 CD cord-015369-72cjogxz 1255 7 women woman NNS cord-015369-72cjogxz 1255 8 , , , cord-015369-72cjogxz 1255 9 15 15 CD cord-015369-72cjogxz 1255 10 men man NNS cord-015369-72cjogxz 1255 11 ; ; : cord-015369-72cjogxz 1255 12 mean mean VB cord-015369-72cjogxz 1255 13 age age NN cord-015369-72cjogxz 1255 14 64.48 64.48 CD cord-015369-72cjogxz 1255 15 years year NNS cord-015369-72cjogxz 1255 16 ) ) -RRB- cord-015369-72cjogxz 1255 17 underwent undergo VBD cord-015369-72cjogxz 1255 18 a a DT cord-015369-72cjogxz 1255 19 robotic robotic JJ cord-015369-72cjogxz 1255 20 lobectomy lobectomy NN cord-015369-72cjogxz 1255 21 for for IN cord-015369-72cjogxz 1255 22 early early JJ cord-015369-72cjogxz 1255 23 stage stage NN cord-015369-72cjogxz 1255 24 NSCLC NSCLC NNP cord-015369-72cjogxz 1255 25 ( ( -LRB- cord-015369-72cjogxz 1255 26 clinical clinical JJ cord-015369-72cjogxz 1255 27 stage stage NN cord-015369-72cjogxz 1255 28 IA IA NNP cord-015369-72cjogxz 1255 29 or or CC cord-015369-72cjogxz 1255 30 IB IB NNP cord-015369-72cjogxz 1255 31 ) ) -RRB- cord-015369-72cjogxz 1255 32 . . . cord-015369-72cjogxz 1256 1 Results result NNS cord-015369-72cjogxz 1256 2 . . . cord-015369-72cjogxz 1257 1 Distribution distribution NN cord-015369-72cjogxz 1257 2 of of IN cord-015369-72cjogxz 1257 3 resected resected JJ cord-015369-72cjogxz 1257 4 lobes lobe NNS cord-015369-72cjogxz 1257 5 were be VBD cord-015369-72cjogxz 1257 6 left leave VBN cord-015369-72cjogxz 1257 7 upper upper JJ cord-015369-72cjogxz 1257 8 lobes lobe NNS cord-015369-72cjogxz 1257 9 4 4 CD cord-015369-72cjogxz 1257 10 , , , cord-015369-72cjogxz 1257 11 left leave VBD cord-015369-72cjogxz 1257 12 lower low JJR cord-015369-72cjogxz 1257 13 lobes lobe NNS cord-015369-72cjogxz 1257 14 6 6 CD cord-015369-72cjogxz 1257 15 , , , cord-015369-72cjogxz 1257 16 right right JJ cord-015369-72cjogxz 1257 17 upper upper JJ cord-015369-72cjogxz 1257 18 lobes lobe NNS cord-015369-72cjogxz 1257 19 8 8 CD cord-015369-72cjogxz 1257 20 and and CC cord-015369-72cjogxz 1257 21 right right RB cord-015369-72cjogxz 1257 22 lower low JJR cord-015369-72cjogxz 1257 23 lobes lobe NNS cord-015369-72cjogxz 1257 24 9 9 CD cord-015369-72cjogxz 1257 25 . . . cord-015369-72cjogxz 1258 1 There there EX cord-015369-72cjogxz 1258 2 were be VBD cord-015369-72cjogxz 1258 3 4 4 CD cord-015369-72cjogxz 1258 4 intraoperative intraoperative JJ cord-015369-72cjogxz 1258 5 conversions conversion NNS cord-015369-72cjogxz 1258 6 to to TO cord-015369-72cjogxz 1258 7 open open VB cord-015369-72cjogxz 1258 8 thoracotomy thoracotomy NN cord-015369-72cjogxz 1258 9 ( ( -LRB- cord-015369-72cjogxz 1258 10 one one CD cord-015369-72cjogxz 1258 11 major major JJ cord-015369-72cjogxz 1258 12 bleeding bleeding NN cord-015369-72cjogxz 1258 13 , , , cord-015369-72cjogxz 1258 14 two two CD cord-015369-72cjogxz 1258 15 minor minor JJ cord-015369-72cjogxz 1258 16 bleedings bleeding NNS cord-015369-72cjogxz 1258 17 , , , cord-015369-72cjogxz 1258 18 one one CD cord-015369-72cjogxz 1258 19 variant variant NN cord-015369-72cjogxz 1258 20 course course NN cord-015369-72cjogxz 1258 21 of of IN cord-015369-72cjogxz 1258 22 the the DT cord-015369-72cjogxz 1258 23 pulmonary pulmonary JJ cord-015369-72cjogxz 1258 24 artery artery NN cord-015369-72cjogxz 1258 25 ) ) -RRB- cord-015369-72cjogxz 1258 26 . . . cord-015369-72cjogxz 1259 1 Postoperative postoperative JJ cord-015369-72cjogxz 1259 2 complications complication NNS cord-015369-72cjogxz 1259 3 included include VBD cord-015369-72cjogxz 1259 4 prolonged prolonged JJ cord-015369-72cjogxz 1259 5 air air NN cord-015369-72cjogxz 1259 6 leak leak NN cord-015369-72cjogxz 1259 7 ( ( -LRB- cord-015369-72cjogxz 1259 8 6 6 CD cord-015369-72cjogxz 1259 9 ) ) -RRB- cord-015369-72cjogxz 1259 10 , , , cord-015369-72cjogxz 1259 11 colonic colonic JJ cord-015369-72cjogxz 1259 12 perforation perforation NN cord-015369-72cjogxz 1259 13 ( ( -LRB- cord-015369-72cjogxz 1259 14 1 1 CD cord-015369-72cjogxz 1259 15 ) ) -RRB- cord-015369-72cjogxz 1259 16 , , , cord-015369-72cjogxz 1259 17 and and CC cord-015369-72cjogxz 1259 18 intermittend intermittend JJ cord-015369-72cjogxz 1259 19 atrial atrial JJ cord-015369-72cjogxz 1259 20 fibrillation fibrillation NN cord-015369-72cjogxz 1259 21 ( ( -LRB- cord-015369-72cjogxz 1259 22 1 1 CD cord-015369-72cjogxz 1259 23 ) ) -RRB- cord-015369-72cjogxz 1259 24 . . . cord-015369-72cjogxz 1260 1 Length length NN cord-015369-72cjogxz 1260 2 of of IN cord-015369-72cjogxz 1260 3 hospital hospital NN cord-015369-72cjogxz 1260 4 stay stay NN cord-015369-72cjogxz 1260 5 was be VBD cord-015369-72cjogxz 1260 6 median median JJ cord-015369-72cjogxz 1261 1 11 11 CD cord-015369-72cjogxz 1261 2 ( ( -LRB- cord-015369-72cjogxz 1261 3 7 7 CD cord-015369-72cjogxz 1261 4 - - SYM cord-015369-72cjogxz 1261 5 53 53 CD cord-015369-72cjogxz 1261 6 ) ) -RRB- cord-015369-72cjogxz 1261 7 days day NNS cord-015369-72cjogxz 1261 8 . . . cord-015369-72cjogxz 1262 1 30-day 30-day CD cord-015369-72cjogxz 1262 2 mortality mortality NN cord-015369-72cjogxz 1262 3 was be VBD cord-015369-72cjogxz 1262 4 one one CD cord-015369-72cjogxz 1262 5 ( ( -LRB- cord-015369-72cjogxz 1262 6 3.7 3.7 CD cord-015369-72cjogxz 1262 7 % % NN cord-015369-72cjogxz 1262 8 ) ) -RRB- cord-015369-72cjogxz 1262 9 . . . cord-015369-72cjogxz 1263 1 Overall overall JJ cord-015369-72cjogxz 1263 2 median median JJ cord-015369-72cjogxz 1263 3 operative operative JJ cord-015369-72cjogxz 1263 4 time time NN cord-015369-72cjogxz 1263 5 was be VBD cord-015369-72cjogxz 1263 6 3 3 CD cord-015369-72cjogxz 1263 7 h h NN cord-015369-72cjogxz 1263 8 and and CC cord-015369-72cjogxz 1263 9 28 28 CD cord-015369-72cjogxz 1263 10 min min NN cord-015369-72cjogxz 1263 11 ( ( -LRB- cord-015369-72cjogxz 1263 12 range range NNP cord-015369-72cjogxz 1263 13 2:15 2:15 CD cord-015369-72cjogxz 1263 14 h h NN cord-015369-72cjogxz 1263 15 to to IN cord-015369-72cjogxz 1263 16 6:30 6:30 CD cord-015369-72cjogxz 1263 17 h h NN cord-015369-72cjogxz 1263 18 , , , cord-015369-72cjogxz 1263 19 mean mean JJ cord-015369-72cjogxz 1263 20 3:45 3:45 CD cord-015369-72cjogxz 1263 21 h h NN cord-015369-72cjogxz 1263 22 ) ) -RRB- cord-015369-72cjogxz 1263 23 . . . cord-015369-72cjogxz 1264 1 After after IN cord-015369-72cjogxz 1264 2 the the DT cord-015369-72cjogxz 1264 3 first first JJ cord-015369-72cjogxz 1264 4 seven seven CD cord-015369-72cjogxz 1264 5 patients patient NNS cord-015369-72cjogxz 1264 6 the the DT cord-015369-72cjogxz 1264 7 initial initial JJ cord-015369-72cjogxz 1264 8 posterior posterior JJ cord-015369-72cjogxz 1264 9 approach approach NN cord-015369-72cjogxz 1264 10 was be VBD cord-015369-72cjogxz 1264 11 switched switch VBN cord-015369-72cjogxz 1264 12 to to IN cord-015369-72cjogxz 1264 13 an an DT cord-015369-72cjogxz 1264 14 anterior anterior JJ cord-015369-72cjogxz 1264 15 one one NN cord-015369-72cjogxz 1264 16 , , , cord-015369-72cjogxz 1264 17 thus thus RB cord-015369-72cjogxz 1264 18 enabling enable VBG cord-015369-72cjogxz 1264 19 an an DT cord-015369-72cjogxz 1264 20 easier easy JJR cord-015369-72cjogxz 1264 21 hilar hilar JJ cord-015369-72cjogxz 1264 22 dissection dissection NN cord-015369-72cjogxz 1264 23 . . . cord-015369-72cjogxz 1265 1 Another another DT cord-015369-72cjogxz 1265 2 technical technical JJ cord-015369-72cjogxz 1265 3 modification modification NN cord-015369-72cjogxz 1265 4 during during IN cord-015369-72cjogxz 1265 5 this this DT cord-015369-72cjogxz 1265 6 first first JJ cord-015369-72cjogxz 1265 7 series series NN cord-015369-72cjogxz 1265 8 was be VBD cord-015369-72cjogxz 1265 9 the the DT cord-015369-72cjogxz 1265 10 introduction introduction NN cord-015369-72cjogxz 1265 11 of of IN cord-015369-72cjogxz 1265 12 a a DT cord-015369-72cjogxz 1265 13 new new JJ cord-015369-72cjogxz 1265 14 vessel vessel NN cord-015369-72cjogxz 1265 15 - - HYPH cord-015369-72cjogxz 1265 16 sealing seal VBG cord-015369-72cjogxz 1265 17 device device NN cord-015369-72cjogxz 1265 18 ( ( -LRB- cord-015369-72cjogxz 1265 19 Hem Hem NNP cord-015369-72cjogxz 1265 20 - - HYPH cord-015369-72cjogxz 1265 21 O O NNP cord-015369-72cjogxz 1265 22 - - HYPH cord-015369-72cjogxz 1265 23 Lok Lok NNP cord-015369-72cjogxz 1265 24 + + CC cord-015369-72cjogxz 1265 25 -Clip -Clip NNP cord-015369-72cjogxz 1265 26 ) ) -RRB- cord-015369-72cjogxz 1265 27 instead instead RB cord-015369-72cjogxz 1265 28 of of IN cord-015369-72cjogxz 1265 29 ligation ligation NN cord-015369-72cjogxz 1265 30 / / SYM cord-015369-72cjogxz 1265 31 stapling stapling NN cord-015369-72cjogxz 1265 32 of of IN cord-015369-72cjogxz 1265 33 the the DT cord-015369-72cjogxz 1265 34 major major JJ cord-015369-72cjogxz 1265 35 pulmonary pulmonary JJ cord-015369-72cjogxz 1265 36 vessels vessel NNS cord-015369-72cjogxz 1265 37 . . . cord-015369-72cjogxz 1266 1 Conclusions conclusion NNS cord-015369-72cjogxz 1266 2 . . . cord-015369-72cjogxz 1267 1 Robotic robotic JJ cord-015369-72cjogxz 1267 2 lobectomy lobectomy NN cord-015369-72cjogxz 1267 3 has have VBZ cord-015369-72cjogxz 1267 4 been be VBN cord-015369-72cjogxz 1267 5 proven prove VBN cord-015369-72cjogxz 1267 6 to to TO cord-015369-72cjogxz 1267 7 be be VB cord-015369-72cjogxz 1267 8 feasible feasible JJ cord-015369-72cjogxz 1267 9 and and CC cord-015369-72cjogxz 1267 10 save save VB cord-015369-72cjogxz 1267 11 in in IN cord-015369-72cjogxz 1267 12 our -PRON- PRP$ cord-015369-72cjogxz 1267 13 initial initial JJ cord-015369-72cjogxz 1267 14 series series NN cord-015369-72cjogxz 1267 15 in in IN cord-015369-72cjogxz 1267 16 a a DT cord-015369-72cjogxz 1267 17 learning learning NN cord-015369-72cjogxz 1267 18 curve curve NN cord-015369-72cjogxz 1267 19 setting setting NN cord-015369-72cjogxz 1267 20 . . . cord-015369-72cjogxz 1268 1 Longer longer RB cord-015369-72cjogxz 1268 2 follow follow VB cord-015369-72cjogxz 1268 3 up up RP cord-015369-72cjogxz 1268 4 and and CC cord-015369-72cjogxz 1268 5 randomized randomize VBN cord-015369-72cjogxz 1268 6 controlled control VBN cord-015369-72cjogxz 1268 7 trials trial NNS cord-015369-72cjogxz 1268 8 are be VBP cord-015369-72cjogxz 1268 9 necessary necessary JJ cord-015369-72cjogxz 1268 10 to to TO cord-015369-72cjogxz 1268 11 evaluate evaluate VB cord-015369-72cjogxz 1268 12 a a DT cord-015369-72cjogxz 1268 13 potential potential JJ cord-015369-72cjogxz 1268 14 benefit benefit NN cord-015369-72cjogxz 1268 15 over over IN cord-015369-72cjogxz 1268 16 open open JJ cord-015369-72cjogxz 1268 17 and and CC cord-015369-72cjogxz 1268 18 conventional conventional JJ cord-015369-72cjogxz 1268 19 VATS vat NNS cord-015369-72cjogxz 1268 20 approaches approach NNS cord-015369-72cjogxz 1268 21 . . . cord-015369-72cjogxz 1269 1 Background background NN cord-015369-72cjogxz 1269 2 . . . cord-015369-72cjogxz 1270 1 Acute acute JJ cord-015369-72cjogxz 1270 2 post post JJ cord-015369-72cjogxz 1270 3 intubation intubation NN cord-015369-72cjogxz 1270 4 laceration laceration NN cord-015369-72cjogxz 1270 5 of of IN cord-015369-72cjogxz 1270 6 the the DT cord-015369-72cjogxz 1270 7 trachea trachea NN cord-015369-72cjogxz 1270 8 is be VBZ cord-015369-72cjogxz 1270 9 a a DT cord-015369-72cjogxz 1270 10 rare rare JJ cord-015369-72cjogxz 1270 11 , , , cord-015369-72cjogxz 1270 12 but but CC cord-015369-72cjogxz 1270 13 serious serious JJ cord-015369-72cjogxz 1270 14 complication complication NN cord-015369-72cjogxz 1270 15 . . . cord-015369-72cjogxz 1271 1 We -PRON- PRP cord-015369-72cjogxz 1271 2 report report VBP cord-015369-72cjogxz 1271 3 our -PRON- PRP$ cord-015369-72cjogxz 1271 4 experience experience NN cord-015369-72cjogxz 1271 5 with with IN cord-015369-72cjogxz 1271 6 the the DT cord-015369-72cjogxz 1271 7 transcervical transcervical JJ cord-015369-72cjogxz 1271 8 approach approach NN cord-015369-72cjogxz 1271 9 and and CC cord-015369-72cjogxz 1271 10 direct direct JJ cord-015369-72cjogxz 1271 11 correction correction NN cord-015369-72cjogxz 1271 12 of of IN cord-015369-72cjogxz 1271 13 the the DT cord-015369-72cjogxz 1271 14 tear tear NN cord-015369-72cjogxz 1271 15 through through IN cord-015369-72cjogxz 1271 16 a a DT cord-015369-72cjogxz 1271 17 T t NN cord-015369-72cjogxz 1271 18 - - HYPH cord-015369-72cjogxz 1271 19 shaped shape VBN cord-015369-72cjogxz 1271 20 anterior anterior JJ cord-015369-72cjogxz 1271 21 tracheotomy tracheotomy NN cord-015369-72cjogxz 1271 22 . . . cord-015369-72cjogxz 1272 1 Methods method NNS cord-015369-72cjogxz 1272 2 . . . cord-015369-72cjogxz 1273 1 In in IN cord-015369-72cjogxz 1273 2 a a DT cord-015369-72cjogxz 1273 3 retrospective retrospective JJ cord-015369-72cjogxz 1273 4 study study NN cord-015369-72cjogxz 1273 5 we -PRON- PRP cord-015369-72cjogxz 1273 6 analyzed analyze VBD cord-015369-72cjogxz 1273 7 the the DT cord-015369-72cjogxz 1273 8 course course NN cord-015369-72cjogxz 1273 9 of of IN cord-015369-72cjogxz 1273 10 10 10 CD cord-015369-72cjogxz 1273 11 patients patient NNS cord-015369-72cjogxz 1273 12 ( ( -LRB- cord-015369-72cjogxz 1273 13 9 9 CD cord-015369-72cjogxz 1273 14 female female NN cord-015369-72cjogxz 1273 15 , , , cord-015369-72cjogxz 1273 16 1 1 CD cord-015369-72cjogxz 1273 17 male male NN cord-015369-72cjogxz 1273 18 ; ; : cord-015369-72cjogxz 1273 19 median median JJ cord-015369-72cjogxz 1273 20 age age NN cord-015369-72cjogxz 1273 21 53.4 53.4 CD cord-015369-72cjogxz 1273 22 , , , cord-015369-72cjogxz 1273 23 range range VBP cord-015369-72cjogxz 1273 24 16 16 CD cord-015369-72cjogxz 1273 25 - - SYM cord-015369-72cjogxz 1273 26 79 79 CD cord-015369-72cjogxz 1273 27 years year NNS cord-015369-72cjogxz 1273 28 ) ) -RRB- cord-015369-72cjogxz 1273 29 . . . cord-015369-72cjogxz 1274 1 In in IN cord-015369-72cjogxz 1274 2 eight eight CD cord-015369-72cjogxz 1274 3 patients patient NNS cord-015369-72cjogxz 1274 4 the the DT cord-015369-72cjogxz 1274 5 tracheal tracheal JJ cord-015369-72cjogxz 1274 6 injury injury NN cord-015369-72cjogxz 1274 7 was be VBD cord-015369-72cjogxz 1274 8 due due JJ cord-015369-72cjogxz 1274 9 to to IN cord-015369-72cjogxz 1274 10 emergency emergency NN cord-015369-72cjogxz 1274 11 intubation intubation NN cord-015369-72cjogxz 1274 12 and and CC cord-015369-72cjogxz 1274 13 in in IN cord-015369-72cjogxz 1274 14 two two CD cord-015369-72cjogxz 1274 15 patients patient NNS cord-015369-72cjogxz 1274 16 it -PRON- PRP cord-015369-72cjogxz 1274 17 occurred occur VBD cord-015369-72cjogxz 1274 18 during during IN cord-015369-72cjogxz 1274 19 percutaneous percutaneous JJ cord-015369-72cjogxz 1274 20 tracheostomy tracheostomy NN cord-015369-72cjogxz 1274 21 . . . cord-015369-72cjogxz 1275 1 The the DT cord-015369-72cjogxz 1275 2 lesions lesion NNS cord-015369-72cjogxz 1275 3 were be VBD cord-015369-72cjogxz 1275 4 located locate VBN cord-015369-72cjogxz 1275 5 in in IN cord-015369-72cjogxz 1275 6 the the DT cord-015369-72cjogxz 1275 7 membranous membranous JJ cord-015369-72cjogxz 1275 8 part part NN cord-015369-72cjogxz 1275 9 of of IN cord-015369-72cjogxz 1275 10 the the DT cord-015369-72cjogxz 1275 11 trachea trachea NN cord-015369-72cjogxz 1275 12 and and CC cord-015369-72cjogxz 1275 13 the the DT cord-015369-72cjogxz 1275 14 mean mean JJ cord-015369-72cjogxz 1275 15 length length NN cord-015369-72cjogxz 1275 16 was be VBD cord-015369-72cjogxz 1275 17 6,5 6,5 CD cord-015369-72cjogxz 1276 1 ( ( -LRB- cord-015369-72cjogxz 1276 2 range range NNP cord-015369-72cjogxz 1276 3 5 5 CD cord-015369-72cjogxz 1276 4 - - SYM cord-015369-72cjogxz 1276 5 10 10 CD cord-015369-72cjogxz 1276 6 ) ) -RRB- cord-015369-72cjogxz 1276 7 cm cm NNS cord-015369-72cjogxz 1276 8 . . . cord-015369-72cjogxz 1277 1 All all DT cord-015369-72cjogxz 1277 2 patients patient NNS cord-015369-72cjogxz 1277 3 underwent undergo VBD cord-015369-72cjogxz 1277 4 surgical surgical JJ cord-015369-72cjogxz 1277 5 repair repair NN cord-015369-72cjogxz 1277 6 immediately immediately RB cord-015369-72cjogxz 1277 7 after after IN cord-015369-72cjogxz 1277 8 diagnosis diagnosis NN cord-015369-72cjogxz 1277 9 . . . cord-015369-72cjogxz 1278 1 The the DT cord-015369-72cjogxz 1278 2 repair repair NN cord-015369-72cjogxz 1278 3 was be VBD cord-015369-72cjogxz 1278 4 carried carry VBN cord-015369-72cjogxz 1278 5 out out RP cord-015369-72cjogxz 1278 6 through through IN cord-015369-72cjogxz 1278 7 a a DT cord-015369-72cjogxz 1278 8 cervical cervical JJ cord-015369-72cjogxz 1278 9 transversal transversal JJ cord-015369-72cjogxz 1278 10 and and CC cord-015369-72cjogxz 1278 11 longitudinal longitudinal JJ cord-015369-72cjogxz 1278 12 T T NNP cord-015369-72cjogxz 1278 13 - - HYPH cord-015369-72cjogxz 1278 14 shaped shape VBN cord-015369-72cjogxz 1278 15 tracheotomy tracheotomy NN cord-015369-72cjogxz 1278 16 allowing allow VBG cord-015369-72cjogxz 1278 17 the the DT cord-015369-72cjogxz 1278 18 exposure exposure NN cord-015369-72cjogxz 1278 19 of of IN cord-015369-72cjogxz 1278 20 the the DT cord-015369-72cjogxz 1278 21 laceration laceration NN cord-015369-72cjogxz 1278 22 in in IN cord-015369-72cjogxz 1278 23 the the DT cord-015369-72cjogxz 1278 24 posterior posterior JJ cord-015369-72cjogxz 1278 25 wall wall NN cord-015369-72cjogxz 1278 26 of of IN cord-015369-72cjogxz 1278 27 the the DT cord-015369-72cjogxz 1278 28 trachea trachea NN cord-015369-72cjogxz 1278 29 which which WDT cord-015369-72cjogxz 1278 30 was be VBD cord-015369-72cjogxz 1278 31 mended mend VBN cord-015369-72cjogxz 1278 32 by by IN cord-015369-72cjogxz 1278 33 intraluminal intraluminal JJ cord-015369-72cjogxz 1278 34 running running NN cord-015369-72cjogxz 1278 35 suture suture NN cord-015369-72cjogxz 1278 36 with with IN cord-015369-72cjogxz 1278 37 4 4 CD cord-015369-72cjogxz 1278 38 - - SYM cord-015369-72cjogxz 1278 39 0 0 CD cord-015369-72cjogxz 1278 40 PDS pd NNS cord-015369-72cjogxz 1278 41 . . . cord-015369-72cjogxz 1279 1 Results result NNS cord-015369-72cjogxz 1279 2 . . . cord-015369-72cjogxz 1280 1 All all DT cord-015369-72cjogxz 1280 2 patients patient NNS cord-015369-72cjogxz 1280 3 recovered recover VBD cord-015369-72cjogxz 1280 4 well well RB cord-015369-72cjogxz 1280 5 and and CC cord-015369-72cjogxz 1280 6 were be VBD cord-015369-72cjogxz 1280 7 discharged discharge VBN cord-015369-72cjogxz 1280 8 from from IN cord-015369-72cjogxz 1280 9 the the DT cord-015369-72cjogxz 1280 10 hospital hospital NN cord-015369-72cjogxz 1280 11 . . . cord-015369-72cjogxz 1281 1 The the DT cord-015369-72cjogxz 1281 2 endoscopic endoscopic NNS cord-015369-72cjogxz 1281 3 follow follow NN cord-015369-72cjogxz 1281 4 - - HYPH cord-015369-72cjogxz 1281 5 up up NN cord-015369-72cjogxz 1281 6 at at IN cord-015369-72cjogxz 1281 7 1 1 CD cord-015369-72cjogxz 1281 8 , , , cord-015369-72cjogxz 1281 9 3 3 CD cord-015369-72cjogxz 1281 10 and and CC cord-015369-72cjogxz 1281 11 6 6 CD cord-015369-72cjogxz 1281 12 months month NNS cord-015369-72cjogxz 1281 13 shows show VBZ cord-015369-72cjogxz 1281 14 no no DT cord-015369-72cjogxz 1281 15 evidence evidence NN cord-015369-72cjogxz 1281 16 for for IN cord-015369-72cjogxz 1281 17 tracheal tracheal JJ cord-015369-72cjogxz 1281 18 stenosis stenosis NN cord-015369-72cjogxz 1281 19 or or CC cord-015369-72cjogxz 1281 20 fistula fistula NN cord-015369-72cjogxz 1281 21 . . . cord-015369-72cjogxz 1282 1 Conclusions conclusion NNS cord-015369-72cjogxz 1282 2 . . . cord-015369-72cjogxz 1283 1 Transcervical Transcervical NNP cord-015369-72cjogxz 1283 2 T t NN cord-015369-72cjogxz 1283 3 - - HYPH cord-015369-72cjogxz 1283 4 shaped shape VBN cord-015369-72cjogxz 1283 5 tracheotomy tracheotomy NN cord-015369-72cjogxz 1283 6 is be VBZ cord-015369-72cjogxz 1283 7 a a DT cord-015369-72cjogxz 1283 8 minimally minimally RB cord-015369-72cjogxz 1283 9 invasive invasive JJ cord-015369-72cjogxz 1283 10 approach approach NN cord-015369-72cjogxz 1283 11 for for IN cord-015369-72cjogxz 1283 12 the the DT cord-015369-72cjogxz 1283 13 repair repair NN cord-015369-72cjogxz 1283 14 of of IN cord-015369-72cjogxz 1283 15 postintubation postintubation NN cord-015369-72cjogxz 1283 16 tracheal tracheal NN cord-015369-72cjogxz 1283 17 injury injury NN cord-015369-72cjogxz 1283 18 . . . cord-015369-72cjogxz 1284 1 This this DT cord-015369-72cjogxz 1284 2 technique technique NN cord-015369-72cjogxz 1284 3 allows allow VBZ cord-015369-72cjogxz 1284 4 exposure exposure NN cord-015369-72cjogxz 1284 5 of of IN cord-015369-72cjogxz 1284 6 the the DT cord-015369-72cjogxz 1284 7 entire entire JJ cord-015369-72cjogxz 1284 8 length length NN cord-015369-72cjogxz 1284 9 of of IN cord-015369-72cjogxz 1284 10 the the DT cord-015369-72cjogxz 1284 11 trachea trachea NN cord-015369-72cjogxz 1284 12 and and CC cord-015369-72cjogxz 1284 13 direct direct JJ cord-015369-72cjogxz 1284 14 suturing suturing NN cord-015369-72cjogxz 1284 15 of of IN cord-015369-72cjogxz 1284 16 the the DT cord-015369-72cjogxz 1284 17 tracheal tracheal JJ cord-015369-72cjogxz 1284 18 wall wall NN cord-015369-72cjogxz 1284 19 with with IN cord-015369-72cjogxz 1284 20 excellent excellent JJ cord-015369-72cjogxz 1284 21 results result NNS cord-015369-72cjogxz 1284 22 . . . cord-015369-72cjogxz 1285 1 We -PRON- PRP cord-015369-72cjogxz 1285 2 recommend recommend VBP cord-015369-72cjogxz 1285 3 this this DT cord-015369-72cjogxz 1285 4 approach approach NN cord-015369-72cjogxz 1285 5 for for IN cord-015369-72cjogxz 1285 6 repair repair NN cord-015369-72cjogxz 1285 7 of of IN cord-015369-72cjogxz 1285 8 iatrogenic iatrogenic JJ cord-015369-72cjogxz 1285 9 postintubation postintubation NN cord-015369-72cjogxz 1285 10 tracheal tracheal NN cord-015369-72cjogxz 1285 11 lesions lesion NNS cord-015369-72cjogxz 1285 12 requiring require VBG cord-015369-72cjogxz 1285 13 surgery surgery NN cord-015369-72cjogxz 1285 14 . . . cord-015369-72cjogxz 1286 1 Totalrekonstruktion Totalrekonstruktion NNP cord-015369-72cjogxz 1286 2 der der NNP cord-015369-72cjogxz 1286 3 Trachea Trachea NNP cord-015369-72cjogxz 1286 4 ( ( -LRB- cord-015369-72cjogxz 1286 5 1980 1980 CD cord-015369-72cjogxz 1286 6 ) ) -RRB- cord-015369-72cjogxz 1287 1 mit mit NNP cord-015369-72cjogxz 1287 2 Thoraxtrauma Thoraxtrauma NNP cord-015369-72cjogxz 1287 3 nach nach NNP cord-015369-72cjogxz 1287 4 28 28 CD cord-015369-72cjogxz 1287 5 Jahren Jahren NNP cord-015369-72cjogxz 1287 6 _SP cord-015369-72cjogxz 1288 1 The the DT cord-015369-72cjogxz 1288 2 importance importance NN cord-015369-72cjogxz 1288 3 of of IN cord-015369-72cjogxz 1288 4 risk risk NN cord-015369-72cjogxz 1288 5 management management NN cord-015369-72cjogxz 1288 6 for for IN cord-015369-72cjogxz 1288 7 patient patient JJ cord-015369-72cjogxz 1288 8 safety safety NN cord-015369-72cjogxz 1288 9 in in IN cord-015369-72cjogxz 1288 10 surgery surgery NN cord-015369-72cjogxz 1288 11 S. S. NNP cord-015369-72cjogxz 1288 12 Kriwanek Kriwanek NNP cord-015369-72cjogxz 1288 13 Background Background NNP cord-015369-72cjogxz 1288 14 . . . cord-015369-72cjogxz 1289 1 Although although IN cord-015369-72cjogxz 1289 2 the the DT cord-015369-72cjogxz 1289 3 concept concept NN cord-015369-72cjogxz 1289 4 of of IN cord-015369-72cjogxz 1289 5 risk risk NN cord-015369-72cjogxz 1289 6 management management NN cord-015369-72cjogxz 1289 7 is be VBZ cord-015369-72cjogxz 1289 8 rather rather RB cord-015369-72cjogxz 1289 9 new new JJ cord-015369-72cjogxz 1289 10 in in IN cord-015369-72cjogxz 1289 11 surgery surgery NN cord-015369-72cjogxz 1289 12 it -PRON- PRP cord-015369-72cjogxz 1289 13 is be VBZ cord-015369-72cjogxz 1289 14 gaining gain VBG cord-015369-72cjogxz 1289 15 importance importance NN cord-015369-72cjogxz 1289 16 to to TO cord-015369-72cjogxz 1289 17 ensure ensure VB cord-015369-72cjogxz 1289 18 increased increase VBN cord-015369-72cjogxz 1289 19 patient patient JJ cord-015369-72cjogxz 1289 20 safety safety NN cord-015369-72cjogxz 1289 21 . . . cord-015369-72cjogxz 1290 1 Methods method NNS cord-015369-72cjogxz 1290 2 and and CC cord-015369-72cjogxz 1290 3 results result NNS cord-015369-72cjogxz 1290 4 . . . cord-015369-72cjogxz 1291 1 The the DT cord-015369-72cjogxz 1291 2 process process NN cord-015369-72cjogxz 1291 3 of of IN cord-015369-72cjogxz 1291 4 risk risk NN cord-015369-72cjogxz 1291 5 managements management NNS cord-015369-72cjogxz 1291 6 consists consist VBZ cord-015369-72cjogxz 1291 7 of of IN cord-015369-72cjogxz 1291 8 evaluation evaluation NN cord-015369-72cjogxz 1291 9 , , , cord-015369-72cjogxz 1291 10 assessment assessment NN cord-015369-72cjogxz 1291 11 , , , cord-015369-72cjogxz 1291 12 and and CC cord-015369-72cjogxz 1291 13 reduction reduction NN cord-015369-72cjogxz 1291 14 of of IN cord-015369-72cjogxz 1291 15 different different JJ cord-015369-72cjogxz 1291 16 risks risk NNS cord-015369-72cjogxz 1291 17 . . . cord-015369-72cjogxz 1292 1 Different different JJ cord-015369-72cjogxz 1292 2 analytic analytic JJ cord-015369-72cjogxz 1292 3 procedures procedure NNS cord-015369-72cjogxz 1292 4 as as IN cord-015369-72cjogxz 1292 5 the the DT cord-015369-72cjogxz 1292 6 3-F 3-f CD cord-015369-72cjogxz 1292 7 method method NN cord-015369-72cjogxz 1292 8 ( ( -LRB- cord-015369-72cjogxz 1292 9 3 3 CD cord-015369-72cjogxz 1292 10 factors factor NNS cord-015369-72cjogxz 1292 11 method method NN cord-015369-72cjogxz 1292 12 ) ) -RRB- cord-015369-72cjogxz 1292 13 or or CC cord-015369-72cjogxz 1292 14 the the DT cord-015369-72cjogxz 1292 15 FMEA FMEA NNP cord-015369-72cjogxz 1292 16 ( ( -LRB- cord-015369-72cjogxz 1292 17 failure failure NN cord-015369-72cjogxz 1292 18 mode mode NN cord-015369-72cjogxz 1292 19 and and CC cord-015369-72cjogxz 1292 20 effect effect NN cord-015369-72cjogxz 1292 21 analysis analysis NN cord-015369-72cjogxz 1292 22 ) ) -RRB- cord-015369-72cjogxz 1292 23 help help VBP cord-015369-72cjogxz 1292 24 to to TO cord-015369-72cjogxz 1292 25 stratify stratify VB cord-015369-72cjogxz 1292 26 risks risk NNS cord-015369-72cjogxz 1292 27 and and CC cord-015369-72cjogxz 1292 28 classify classify VB cord-015369-72cjogxz 1292 29 the the DT cord-015369-72cjogxz 1292 30 urgency urgency NN cord-015369-72cjogxz 1292 31 of of IN cord-015369-72cjogxz 1292 32 risk risk NN cord-015369-72cjogxz 1292 33 - - HYPH cord-015369-72cjogxz 1292 34 reducing reduce VBG cord-015369-72cjogxz 1292 35 actions action NNS cord-015369-72cjogxz 1292 36 . . . cord-015369-72cjogxz 1293 1 The the DT cord-015369-72cjogxz 1293 2 first first JJ cord-015369-72cjogxz 1293 3 and and CC cord-015369-72cjogxz 1293 4 most most RBS cord-015369-72cjogxz 1293 5 important important JJ cord-015369-72cjogxz 1293 6 application application NN cord-015369-72cjogxz 1293 7 of of IN cord-015369-72cjogxz 1293 8 risk risk NN cord-015369-72cjogxz 1293 9 management management NN cord-015369-72cjogxz 1293 10 in in IN cord-015369-72cjogxz 1293 11 surgery surgery NN cord-015369-72cjogxz 1293 12 must must MD cord-015369-72cjogxz 1293 13 concern concern VB cord-015369-72cjogxz 1293 14 operative operative JJ cord-015369-72cjogxz 1293 15 procedures procedure NNS cord-015369-72cjogxz 1293 16 . . . cord-015369-72cjogxz 1294 1 Conclusions conclusion NNS cord-015369-72cjogxz 1294 2 . . . cord-015369-72cjogxz 1295 1 The the DT cord-015369-72cjogxz 1295 2 concept concept NN cord-015369-72cjogxz 1295 3 of of IN cord-015369-72cjogxz 1295 4 risk risk NN cord-015369-72cjogxz 1295 5 management management NN cord-015369-72cjogxz 1295 6 represents represent VBZ cord-015369-72cjogxz 1295 7 a a DT cord-015369-72cjogxz 1295 8 new new JJ cord-015369-72cjogxz 1295 9 and and CC cord-015369-72cjogxz 1295 10 interesting interesting JJ cord-015369-72cjogxz 1295 11 approach approach NN cord-015369-72cjogxz 1295 12 in in IN cord-015369-72cjogxz 1295 13 order order NN cord-015369-72cjogxz 1295 14 to to TO cord-015369-72cjogxz 1295 15 increase increase VB cord-015369-72cjogxz 1295 16 patient patient JJ cord-015369-72cjogxz 1295 17 safety safety NN cord-015369-72cjogxz 1295 18 in in IN cord-015369-72cjogxz 1295 19 surgery surgery NN cord-015369-72cjogxz 1295 20 . . . cord-015369-72cjogxz 1296 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 1296 2 . . . cord-015369-72cjogxz 1297 1 Mit Mit NNP cord-015369-72cjogxz 1297 2 der der NNP cord-015369-72cjogxz 1297 3 Kostenreduktion Kostenreduktion NNP cord-015369-72cjogxz 1298 1 bestehen bestehen NNP cord-015369-72cjogxz 1299 1 i -PRON- PRP cord-015369-72cjogxz 1299 2 m be VBP cord-015369-72cjogxz 1299 3 Krankenhauswesen Krankenhauswesen NNP cord-015369-72cjogxz 1300 1 Tendenzen Tendenzen NNP cord-015369-72cjogxz 1300 2 zur zur NNP cord-015369-72cjogxz 1300 3 Verkürzung Verkürzung NNP cord-015369-72cjogxz 1300 4 der der NN cord-015369-72cjogxz 1300 5 stationären stationären NNP cord-015369-72cjogxz 1300 6 Verweildauern Verweildauern NNP cord-015369-72cjogxz 1300 7 . . . cord-015369-72cjogxz 1301 1 Bei Bei NNP cord-015369-72cjogxz 1301 2 der der NNP cord-015369-72cjogxz 1301 3 bedarfs bedarfs NNP cord-015369-72cjogxz 1301 4 - - HYPH cord-015369-72cjogxz 1301 5 und und NNP cord-015369-72cjogxz 1301 6 ressourcengerechten ressourcengerechten NNP cord-015369-72cjogxz 1301 7 Aufnahmeund Aufnahmeund NNP cord-015369-72cjogxz 1301 8 Belegungsplanung Belegungsplanung NNP cord-015369-72cjogxz 1301 9 haben haben XX cord-015369-72cjogxz 1301 10 sich sich NNP cord-015369-72cjogxz 1301 11 in in IN cord-015369-72cjogxz 1301 12 der der NNP cord-015369-72cjogxz 1301 13 Chirurgie Chirurgie NNP cord-015369-72cjogxz 1301 14 Patientenmanagement Patientenmanagement NNP cord-015369-72cjogxz 1301 15 Systeme Systeme NNP cord-015369-72cjogxz 1301 16 etabliert etabliert NN cord-015369-72cjogxz 1301 17 und und IN cord-015369-72cjogxz 1301 18 bewährt bewährt NNP cord-015369-72cjogxz 1301 19 . . . cord-015369-72cjogxz 1302 1 Die die VB cord-015369-72cjogxz 1303 1 Umsetzung Umsetzung NNP cord-015369-72cjogxz 1303 2 eines eine NNS cord-015369-72cjogxz 1303 3 patientenorientierten patientenorientierten VBD cord-015369-72cjogxz 1303 4 Entlassungsmanagements Entlassungsmanagements NNP cord-015369-72cjogxz 1303 5 ist ist VBP cord-015369-72cjogxz 1303 6 häufig häufig NNP cord-015369-72cjogxz 1303 7 nicht nicht NNP cord-015369-72cjogxz 1303 8 ohne ohne NNP cord-015369-72cjogxz 1303 9 Probleme Probleme NNP cord-015369-72cjogxz 1303 10 ; ; : cord-015369-72cjogxz 1303 11 beispielsweise beispielsweise NNP cord-015369-72cjogxz 1303 12 ist ist NNP cord-015369-72cjogxz 1303 13 die die VBP cord-015369-72cjogxz 1304 1 Aktionsfähigkeit Aktionsfähigkeit NNP cord-015369-72cjogxz 1304 2 innerbetrieblicher innerbetrieblicher RB cord-015369-72cjogxz 1305 1 Sozial Sozial NNP cord-015369-72cjogxz 1305 2 - - HYPH cord-015369-72cjogxz 1305 3 und und NNP cord-015369-72cjogxz 1305 4 medizinischer medizinischer NNP cord-015369-72cjogxz 1305 5 Dienste Dienste NNP cord-015369-72cjogxz 1305 6 wegen wegen NNP cord-015369-72cjogxz 1306 1 administrativer administrativer NNP cord-015369-72cjogxz 1306 2 und und IN cord-015369-72cjogxz 1306 3 externer externer NNP cord-015369-72cjogxz 1306 4 Reglementierungen Reglementierungen NNP cord-015369-72cjogxz 1306 5 blockiert blockiert NNP cord-015369-72cjogxz 1306 6 . . . cord-015369-72cjogxz 1307 1 Kann Kann NNP cord-015369-72cjogxz 1307 2 eine eine NNP cord-015369-72cjogxz 1307 3 anspruchs anspruchs NNP cord-015369-72cjogxz 1307 4 - - HYPH cord-015369-72cjogxz 1307 5 und und NNP cord-015369-72cjogxz 1307 6 zeitgerechte zeitgerechte NNP cord-015369-72cjogxz 1307 7 qualitativ qualitativ NNP cord-015369-72cjogxz 1307 8 abgesicherte abgesicherte NNP cord-015369-72cjogxz 1308 1 poststationäre poststationäre NNP cord-015369-72cjogxz 1308 2 häusliche häusliche NNP cord-015369-72cjogxz 1308 3 Nachversorgung Nachversorgung NNP cord-015369-72cjogxz 1308 4 nicht nicht NNP cord-015369-72cjogxz 1308 5 gewährleistet gewährleistet NNP cord-015369-72cjogxz 1308 6 werden werden NNP cord-015369-72cjogxz 1309 1 , , , cord-015369-72cjogxz 1309 2 bedeutet bedeutet NNP cord-015369-72cjogxz 1309 3 dies die VBZ cord-015369-72cjogxz 1309 4 für für NNP cord-015369-72cjogxz 1309 5 Patienten Patienten NNP cord-015369-72cjogxz 1309 6 egal egal NNP cord-015369-72cjogxz 1309 7 welcher welcher NNP cord-015369-72cjogxz 1309 8 chirurgischer chirurgischer NN cord-015369-72cjogxz 1309 9 Disziplin Disziplin NNP cord-015369-72cjogxz 1309 10 , , , cord-015369-72cjogxz 1309 11 , , , cord-015369-72cjogxz 1309 12 Krisenmanagement Krisenmanagement NNP cord-015369-72cjogxz 1309 13 ' ' '' cord-015369-72cjogxz 1309 14 ' ' '' cord-015369-72cjogxz 1309 15 . . . cord-015369-72cjogxz 1310 1 Methodik Methodik NNP cord-015369-72cjogxz 1310 2 . . . cord-015369-72cjogxz 1311 1 Auf Auf NNP cord-015369-72cjogxz 1311 2 der der NN cord-015369-72cjogxz 1311 3 Grundlage Grundlage NNP cord-015369-72cjogxz 1311 4 der der NNP cord-015369-72cjogxz 1311 5 Konzeption Konzeption NNP cord-015369-72cjogxz 1311 6 von von NNP cord-015369-72cjogxz 1311 7 hospitalto hospitalto NNP cord-015369-72cjogxz 1311 8 - - HYPH cord-015369-72cjogxz 1311 9 home home NNP cord-015369-72cjogxz 1312 1 + + CC cord-015369-72cjogxz 1313 1 -mobile -mobile : cord-015369-72cjogxz 1313 2 Gesundheitsservices Gesundheitsservices NNPS cord-015369-72cjogxz 1313 3 und und IN cord-015369-72cjogxz 1313 4 in in IN cord-015369-72cjogxz 1313 5 Zusammenarbeit Zusammenarbeit NNP cord-015369-72cjogxz 1313 6 mit mit NNP cord-015369-72cjogxz 1313 7 der der NNP cord-015369-72cjogxz 1314 1 regional regional NNP cord-015369-72cjogxz 1314 2 zuständigen zuständigen NNP cord-015369-72cjogxz 1314 3 kassenärztlichen kassenärztlichen NNP cord-015369-72cjogxz 1315 1 Vereinigung Vereinigung NNP cord-015369-72cjogxz 1316 1 wurde wurde NNP cord-015369-72cjogxz 1316 2 ein ein NNP cord-015369-72cjogxz 1316 3 klinik klinik NNP cord-015369-72cjogxz 1316 4 - - HYPH cord-015369-72cjogxz 1316 5 und und NNP cord-015369-72cjogxz 1316 6 mobilitätsgestützter mobilitätsgestützter NNP cord-015369-72cjogxz 1316 7 Gesundheitsservice Gesundheitsservice NNP cord-015369-72cjogxz 1317 1 für für NNP cord-015369-72cjogxz 1317 2 das das NNP cord-015369-72cjogxz 1317 3 stationäre stationäre NNP cord-015369-72cjogxz 1317 4 Entlassungs Entlassungs NNP cord-015369-72cjogxz 1317 5 - - HYPH cord-015369-72cjogxz 1317 6 und und NNP cord-015369-72cjogxz 1317 7 poststationäre poststationäre NNP cord-015369-72cjogxz 1317 8 , , , cord-015369-72cjogxz 1317 9 , , , cord-015369-72cjogxz 1317 10 home home NN cord-015369-72cjogxz 1317 11 - - HYPH cord-015369-72cjogxz 1317 12 care care NN cord-015369-72cjogxz 1317 13 ' ' '' cord-015369-72cjogxz 1317 14 ' ' '' cord-015369-72cjogxz 1317 15 Management management NN cord-015369-72cjogxz 1317 16 an an DT cord-015369-72cjogxz 1317 17 der der NN cord-015369-72cjogxz 1317 18 Chirurgischen Chirurgischen NNP cord-015369-72cjogxz 1317 19 Klinik Klinik NNP cord-015369-72cjogxz 1317 20 eines eines NNP cord-015369-72cjogxz 1317 21 Universitätsklinikum Universitätsklinikum NNP cord-015369-72cjogxz 1317 22 , , , cord-015369-72cjogxz 1317 23 hier hier NNP cord-015369-72cjogxz 1317 24 unter unter NNP cord-015369-72cjogxz 1317 25 der der NNP cord-015369-72cjogxz 1317 26 Projektbezeichnung Projektbezeichnung NNP cord-015369-72cjogxz 1317 27 , , , cord-015369-72cjogxz 1317 28 , , , cord-015369-72cjogxz 1317 29 MEDmobil MEDmobil NNP cord-015369-72cjogxz 1317 30 ' ' POS cord-015369-72cjogxz 1317 31 ' ' '' cord-015369-72cjogxz 1317 32 evaluiert evaluiert NN cord-015369-72cjogxz 1317 33 . . . cord-015369-72cjogxz 1318 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1318 2 . . . cord-015369-72cjogxz 1319 1 Die die VB cord-015369-72cjogxz 1319 2 zeitgerechte zeitgerechte NNP cord-015369-72cjogxz 1319 3 Klinikentlassung Klinikentlassung NNP cord-015369-72cjogxz 1319 4 unter unter JJ cord-015369-72cjogxz 1319 5 abgesicherter abgesicherter NN cord-015369-72cjogxz 1319 6 poststationärer poststationärer NN cord-015369-72cjogxz 1320 1 Weiterversorgung Weiterversorgung NNP cord-015369-72cjogxz 1320 2 kann kann NNP cord-015369-72cjogxz 1320 3 mit mit NNP cord-015369-72cjogxz 1320 4 diesem diesem JJ cord-015369-72cjogxz 1320 5 Konzept Konzept NNP cord-015369-72cjogxz 1320 6 selbst selbst NNP cord-015369-72cjogxz 1320 7 in in IN cord-015369-72cjogxz 1320 8 komplizierte komplizierte NNP cord-015369-72cjogxz 1320 9 Umständen Umständen NNP cord-015369-72cjogxz 1320 10 , , , cord-015369-72cjogxz 1320 11 wie wie NNP cord-015369-72cjogxz 1320 12 z. z. NNP cord-015369-72cjogxz 1321 1 B. B. NNP cord-015369-72cjogxz 1321 2 bei bei NNP cord-015369-72cjogxz 1321 3 postoperativen postoperativen NNP cord-015369-72cjogxz 1321 4 Wundheilungsstörungen Wundheilungsstörungen NNP cord-015369-72cjogxz 1321 5 erfolgen erfolgen NNP cord-015369-72cjogxz 1321 6 . . . cord-015369-72cjogxz 1322 1 Die Die NNP cord-015369-72cjogxz 1322 2 Fragmentierung Fragmentierung NNP cord-015369-72cjogxz 1322 3 von von NNP cord-015369-72cjogxz 1322 4 ökonomischer ökonomischer NNP cord-015369-72cjogxz 1323 1 und und NNP cord-015369-72cjogxz 1323 2 medizinisch medizinisch NNP cord-015369-72cjogxz 1323 3 chirurgisch chirurgisch NNP cord-015369-72cjogxz 1323 4 erforderlicher erforderlicher NNP cord-015369-72cjogxz 1323 5 , , , cord-015369-72cjogxz 1323 6 , , , cord-015369-72cjogxz 1323 7 in in IN cord-015369-72cjogxz 1323 8 - - HYPH cord-015369-72cjogxz 1323 9 time time NN cord-015369-72cjogxz 1323 10 ' ' '' cord-015369-72cjogxz 1323 11 ' ' '' cord-015369-72cjogxz 1323 12 Leistungserbringung Leistungserbringung NNP cord-015369-72cjogxz 1323 13 und und IN cord-015369-72cjogxz 1323 14 postoperativer postoperativer NNP cord-015369-72cjogxz 1323 15 Gewährleistung Gewährleistung NNP cord-015369-72cjogxz 1323 16 häuslicher häuslicher NNP cord-015369-72cjogxz 1323 17 Versorgungsnotwendigkeiten Versorgungsnotwendigkeiten NNP cord-015369-72cjogxz 1323 18 kann kann NNP cord-015369-72cjogxz 1324 1 so so RB cord-015369-72cjogxz 1324 2 am be VBP cord-015369-72cjogxz 1324 3 Ende Ende NNP cord-015369-72cjogxz 1324 4 der der NNP cord-015369-72cjogxz 1324 5 Prozesskette Prozesskette NNP cord-015369-72cjogxz 1324 6 in in IN cord-015369-72cjogxz 1324 7 übergreifendem übergreifendem NNP cord-015369-72cjogxz 1324 8 Interesse Interesse NNP cord-015369-72cjogxz 1324 9 gestaltet gestaltet NNP cord-015369-72cjogxz 1324 10 werden werden NNP cord-015369-72cjogxz 1324 11 . . . cord-015369-72cjogxz 1325 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1325 2 . . . cord-015369-72cjogxz 1326 1 Unter Unter NNP cord-015369-72cjogxz 1326 2 Klinikbedingungen Klinikbedingungen NNP cord-015369-72cjogxz 1326 3 ist ist NN cord-015369-72cjogxz 1326 4 das das NNP cord-015369-72cjogxz 1326 5 Konzept Konzept NNP cord-015369-72cjogxz 1326 6 der der NNP cord-015369-72cjogxz 1326 7 Projektgruppe Projektgruppe NNP cord-015369-72cjogxz 1326 8 von von NNP cord-015369-72cjogxz 1326 9 hospital hospital NN cord-015369-72cjogxz 1326 10 - - HYPH cord-015369-72cjogxz 1326 11 to to IN cord-015369-72cjogxz 1326 12 - - HYPH cord-015369-72cjogxz 1326 13 home home NN cord-015369-72cjogxz 1327 1 + + CC cord-015369-72cjogxz 1328 1 -mobile -mobile : cord-015369-72cjogxz 1328 2 Gesundheitsservices Gesundheitsservices NNP cord-015369-72cjogxz 1328 3 eine eine NN cord-015369-72cjogxz 1328 4 patientenorientierte patientenorientierte NN cord-015369-72cjogxz 1328 5 Konsequenz Konsequenz NNP cord-015369-72cjogxz 1328 6 auf auf NNP cord-015369-72cjogxz 1328 7 die die VBP cord-015369-72cjogxz 1329 1 Anforderungen Anforderungen NNP cord-015369-72cjogxz 1329 2 des des FW cord-015369-72cjogxz 1329 3 DRG DRG NNP cord-015369-72cjogxz 1329 4 - - HYPH cord-015369-72cjogxz 1329 5 System System NNP cord-015369-72cjogxz 1329 6 ; ; : cord-015369-72cjogxz 1329 7 insbesondere insbesondere NNP cord-015369-72cjogxz 1329 8 auch auch NNP cord-015369-72cjogxz 1329 9 seitens seitens NNP cord-015369-72cjogxz 1329 10 der der NNP cord-015369-72cjogxz 1329 11 Patienten Patienten NNP cord-015369-72cjogxz 1329 12 . . . cord-015369-72cjogxz 1330 1 Interessen Interessen NNP cord-015369-72cjogxz 1330 2 der der NNP cord-015369-72cjogxz 1330 3 medizinischen medizinischen NNP cord-015369-72cjogxz 1330 4 Leistungserbringer Leistungserbringer NNP cord-015369-72cjogxz 1330 5 , , , cord-015369-72cjogxz 1330 6 der der NNP cord-015369-72cjogxz 1330 7 Krankenhaus Krankenhaus NNP cord-015369-72cjogxz 1330 8 - - HYPH cord-015369-72cjogxz 1330 9 und und NNP cord-015369-72cjogxz 1330 10 der der NNP cord-015369-72cjogxz 1330 11 Versicherungsträger Versicherungsträger NNP cord-015369-72cjogxz 1330 12 werden werden XX cord-015369-72cjogxz 1330 13 auch auch NNP cord-015369-72cjogxz 1330 14 vor vor NNP cord-015369-72cjogxz 1330 15 dem dem NNP cord-015369-72cjogxz 1330 16 Hintergrund Hintergrund NNP cord-015369-72cjogxz 1330 17 eines eines NNP cord-015369-72cjogxz 1330 18 patientenseitigen patientenseitigen NNP cord-015369-72cjogxz 1330 19 , , , cord-015369-72cjogxz 1330 20 , , , cord-015369-72cjogxz 1330 21 Return return NN cord-015369-72cjogxz 1330 22 - - HYPH cord-015369-72cjogxz 1330 23 to to IN cord-015369-72cjogxz 1330 24 - - HYPH cord-015369-72cjogxz 1330 25 Invest invest VB cord-015369-72cjogxz 1330 26 ' ' '' cord-015369-72cjogxz 1330 27 ' ' '' cord-015369-72cjogxz 1330 28 reflektiert reflektiert NN cord-015369-72cjogxz 1330 29 . . . cord-015369-72cjogxz 1331 1 Background background NN cord-015369-72cjogxz 1331 2 . . . cord-015369-72cjogxz 1332 1 Skin skin NN cord-015369-72cjogxz 1332 2 rejection rejection NN cord-015369-72cjogxz 1332 3 in in IN cord-015369-72cjogxz 1332 4 composite composite JJ cord-015369-72cjogxz 1332 5 tissue tissue NN cord-015369-72cjogxz 1332 6 allotransplantation allotransplantation NN cord-015369-72cjogxz 1332 7 ( ( -LRB- cord-015369-72cjogxz 1332 8 CTA CTA NNP cord-015369-72cjogxz 1332 9 ) ) -RRB- cord-015369-72cjogxz 1332 10 is be VBZ cord-015369-72cjogxz 1332 11 the the DT cord-015369-72cjogxz 1332 12 pace pace NN cord-015369-72cjogxz 1332 13 - - HYPH cord-015369-72cjogxz 1332 14 limiting limit VBG cord-015369-72cjogxz 1332 15 obstacle obstacle NN cord-015369-72cjogxz 1332 16 for for IN cord-015369-72cjogxz 1332 17 wider wide JJR cord-015369-72cjogxz 1332 18 adoption adoption NN cord-015369-72cjogxz 1332 19 in in IN cord-015369-72cjogxz 1332 20 clinical clinical JJ cord-015369-72cjogxz 1332 21 practice practice NN cord-015369-72cjogxz 1332 22 . . . cord-015369-72cjogxz 1333 1 This this DT cord-015369-72cjogxz 1333 2 study study NN cord-015369-72cjogxz 1333 3 aims aim VBZ cord-015369-72cjogxz 1333 4 to to TO cord-015369-72cjogxz 1333 5 identify identify VB cord-015369-72cjogxz 1333 6 cytokine cytokine NN cord-015369-72cjogxz 1333 7 network network NN cord-015369-72cjogxz 1333 8 dynamics dynamic NNS cord-015369-72cjogxz 1333 9 mediating mediate VBG cord-015369-72cjogxz 1333 10 acute acute JJ cord-015369-72cjogxz 1333 11 rejection rejection NN cord-015369-72cjogxz 1333 12 in in IN cord-015369-72cjogxz 1333 13 CTA CTA NNP cord-015369-72cjogxz 1333 14 , , , cord-015369-72cjogxz 1333 15 with with IN cord-015369-72cjogxz 1333 16 focus focus NN cord-015369-72cjogxz 1333 17 on on IN cord-015369-72cjogxz 1333 18 skin skin NN cord-015369-72cjogxz 1333 19 . . . cord-015369-72cjogxz 1334 1 Methods method NNS cord-015369-72cjogxz 1334 2 . . . cord-015369-72cjogxz 1335 1 Using use VBG cord-015369-72cjogxz 1335 2 a a DT cord-015369-72cjogxz 1335 3 Brown Brown NNP cord-015369-72cjogxz 1335 4 - - HYPH cord-015369-72cjogxz 1335 5 Norway Norway NNP cord-015369-72cjogxz 1335 6 to to IN cord-015369-72cjogxz 1335 7 Lewis Lewis NNP cord-015369-72cjogxz 1335 8 rat rat NN cord-015369-72cjogxz 1335 9 hind hind JJ cord-015369-72cjogxz 1335 10 - - HYPH cord-015369-72cjogxz 1335 11 limb limb NN cord-015369-72cjogxz 1335 12 allotransplant allotransplant JJ cord-015369-72cjogxz 1335 13 model model NN cord-015369-72cjogxz 1335 14 , , , cord-015369-72cjogxz 1335 15 syngeneic syngeneic NNS cord-015369-72cjogxz 1335 16 [ [ -LRB- cord-015369-72cjogxz 1335 17 n n NN cord-015369-72cjogxz 1335 18 ¼ ¼ NNP cord-015369-72cjogxz 1335 19 10 10 CD cord-015369-72cjogxz 1335 20 ] ] -RRB- cord-015369-72cjogxz 1335 21 and and CC cord-015369-72cjogxz 1335 22 allogeneic allogeneic IN cord-015369-72cjogxz 1335 23 [ [ -LRB- cord-015369-72cjogxz 1335 24 n n NN cord-015369-72cjogxz 1335 25 ¼ ¼ NNP cord-015369-72cjogxz 1335 26 10 10 CD cord-015369-72cjogxz 1335 27 ] ] -RRB- cord-015369-72cjogxz 1335 28 transplants transplant NNS cord-015369-72cjogxz 1335 29 without without IN cord-015369-72cjogxz 1335 30 immunosuppression immunosuppression NN cord-015369-72cjogxz 1335 31 were be VBD cord-015369-72cjogxz 1335 32 studied study VBN cord-015369-72cjogxz 1335 33 . . . cord-015369-72cjogxz 1336 1 120 120 CD cord-015369-72cjogxz 1336 2 skin skin NN cord-015369-72cjogxz 1336 3 and and CC cord-015369-72cjogxz 1336 4 muscle muscle NN cord-015369-72cjogxz 1336 5 biopsies biopsy NNS cord-015369-72cjogxz 1336 6 were be VBD cord-015369-72cjogxz 1336 7 taken take VBN cord-015369-72cjogxz 1336 8 at at IN cord-015369-72cjogxz 1336 9 defined define VBN cord-015369-72cjogxz 1336 10 time time NN cord-015369-72cjogxz 1336 11 points point NNS cord-015369-72cjogxz 1336 12 between between IN cord-015369-72cjogxz 1336 13 day day NN cord-015369-72cjogxz 1336 14 0 0 CD cord-015369-72cjogxz 1336 15 and and CC cord-015369-72cjogxz 1336 16 11 11 CD cord-015369-72cjogxz 1336 17 . . . cord-015369-72cjogxz 1337 1 Protein protein NN cord-015369-72cjogxz 1337 2 levels level NNS cord-015369-72cjogxz 1337 3 of of IN cord-015369-72cjogxz 1337 4 14 14 CD cord-015369-72cjogxz 1337 5 cytokines cytokine NNS cord-015369-72cjogxz 1337 6 known know VBN cord-015369-72cjogxz 1337 7 to to TO cord-015369-72cjogxz 1337 8 be be VB cord-015369-72cjogxz 1337 9 relevant relevant JJ cord-015369-72cjogxz 1337 10 in in IN cord-015369-72cjogxz 1337 11 cellular cellular JJ cord-015369-72cjogxz 1337 12 inflammatory inflammatory JJ cord-015369-72cjogxz 1337 13 responses response NNS cord-015369-72cjogxz 1337 14 were be VBD cord-015369-72cjogxz 1337 15 assessed assess VBN cord-015369-72cjogxz 1337 16 by by IN cord-015369-72cjogxz 1337 17 Luminex Luminex NNP cord-015369-72cjogxz 1337 18 TM TM NNP cord-015369-72cjogxz 1337 19 . . . cord-015369-72cjogxz 1338 1 Expression expression NN cord-015369-72cjogxz 1339 1 ( ( -LRB- cord-015369-72cjogxz 1339 2 Ápg Ápg NNP cord-015369-72cjogxz 1339 3 / / SYM cord-015369-72cjogxz 1339 4 ml ml NN cord-015369-72cjogxz 1339 5 ) ) -RRB- cord-015369-72cjogxz 1339 6 was be VBD cord-015369-72cjogxz 1339 7 read read VBN cord-015369-72cjogxz 1339 8 by by IN cord-015369-72cjogxz 1339 9 measuring measure VBG cord-015369-72cjogxz 1339 10 significant significant JJ cord-015369-72cjogxz 1339 11 differences difference NNS cord-015369-72cjogxz 1339 12 among among IN cord-015369-72cjogxz 1339 13 pairs pair NNS cord-015369-72cjogxz 1339 14 of of IN cord-015369-72cjogxz 1339 15 slopes slope NNS cord-015369-72cjogxz 1339 16 ( ( -LRB- cord-015369-72cjogxz 1339 17 w w NN cord-015369-72cjogxz 1339 18 / / SYM cord-015369-72cjogxz 1339 19 Matlab Matlab NNP cord-015369-72cjogxz 1339 20 ) ) -RRB- cord-015369-72cjogxz 1339 21 for for IN cord-015369-72cjogxz 1339 22 characterization characterization NN cord-015369-72cjogxz 1339 23 of of IN cord-015369-72cjogxz 1339 24 a a DT cord-015369-72cjogxz 1339 25 cytokine cytokine NN cord-015369-72cjogxz 1339 26 network network NN cord-015369-72cjogxz 1339 27 profile profile NN cord-015369-72cjogxz 1339 28 . . . cord-015369-72cjogxz 1340 1 Results result NNS cord-015369-72cjogxz 1340 2 . . . cord-015369-72cjogxz 1341 1 In in IN cord-015369-72cjogxz 1341 2 syngeneic syngeneic NNS cord-015369-72cjogxz 1341 3 transplants transplant NNS cord-015369-72cjogxz 1341 4 , , , cord-015369-72cjogxz 1341 5 IL-1a IL-1a NNP cord-015369-72cjogxz 1341 6 and and CC cord-015369-72cjogxz 1341 7 IL-18 IL-18 NNP cord-015369-72cjogxz 1341 8 were be VBD cord-015369-72cjogxz 1341 9 expressed express VBN cord-015369-72cjogxz 1341 10 in in IN cord-015369-72cjogxz 1341 11 skin skin NN cord-015369-72cjogxz 1341 12 throughout throughout IN cord-015369-72cjogxz 1341 13 the the DT cord-015369-72cjogxz 1341 14 period period NN cord-015369-72cjogxz 1341 15 of of IN cord-015369-72cjogxz 1341 16 observation observation NN cord-015369-72cjogxz 1341 17 , , , cord-015369-72cjogxz 1341 18 with with IN cord-015369-72cjogxz 1341 19 highest high JJS cord-015369-72cjogxz 1341 20 levels level NNS cord-015369-72cjogxz 1341 21 on on IN cord-015369-72cjogxz 1341 22 pod pod NN cord-015369-72cjogxz 1341 23 5 5 CD cord-015369-72cjogxz 1341 24 at at IN cord-015369-72cjogxz 1341 25 an an DT cord-015369-72cjogxz 1341 26 average average JJ cord-015369-72cjogxz 1341 27 IL-1a IL-1a NNP cord-015369-72cjogxz 1341 28 concentration concentration NN cord-015369-72cjogxz 1341 29 of of IN cord-015369-72cjogxz 1341 30 10811 10811 CD cord-015369-72cjogxz 1341 31 pg pg NNP cord-015369-72cjogxz 1341 32 / / SYM cord-015369-72cjogxz 1341 33 ml ml NN cord-015369-72cjogxz 1341 34 ( ( -LRB- cord-015369-72cjogxz 1341 35 > > NFP cord-015369-72cjogxz 1341 36 4 4 CD cord-015369-72cjogxz 1341 37 Â â NN cord-015369-72cjogxz 1341 38 Á á NN cord-015369-72cjogxz 1341 39 from from IN cord-015369-72cjogxz 1341 40 biopsy biopsy NN cord-015369-72cjogxz 1341 41 control control NN cord-015369-72cjogxz 1341 42 ( ( -LRB- cord-015369-72cjogxz 1341 43 BC BC NNP cord-015369-72cjogxz 1341 44 ) ) -RRB- cord-015369-72cjogxz 1341 45 , , , cord-015369-72cjogxz 1341 46 standard standard JJ cord-015369-72cjogxz 1341 47 deviation deviation NN cord-015369-72cjogxz 1341 48 ( ( -LRB- cord-015369-72cjogxz 1341 49 SD SD NNP cord-015369-72cjogxz 1341 50 ) ) -RRB- cord-015369-72cjogxz 1341 51 ¼ ¼ CD cord-015369-72cjogxz 1341 52 6.5 6.5 CD cord-015369-72cjogxz 1341 53 % % NN cord-015369-72cjogxz 1341 54 ) ) -RRB- cord-015369-72cjogxz 1341 55 and and CC cord-015369-72cjogxz 1341 56 IL-18 IL-18 NNP cord-015369-72cjogxz 1341 57 at at IN cord-015369-72cjogxz 1341 58 8256 8256 CD cord-015369-72cjogxz 1341 59 pg pg NN cord-015369-72cjogxz 1341 60 / / SYM cord-015369-72cjogxz 1341 61 ml ml NN cord-015369-72cjogxz 1341 62 ( ( -LRB- cord-015369-72cjogxz 1341 63 > > XX cord-015369-72cjogxz 1341 64 3.77Â 3.77â CD cord-015369-72cjogxz 1341 65 ÁBC ÁBC NNP cord-015369-72cjogxz 1341 66 , , , cord-015369-72cjogxz 1341 67 SD sd NN cord-015369-72cjogxz 1341 68 ¼ ¼ NN cord-015369-72cjogxz 1341 69 18.5 18.5 CD cord-015369-72cjogxz 1341 70 % % NN cord-015369-72cjogxz 1341 71 ) ) -RRB- cord-015369-72cjogxz 1341 72 . . . cord-015369-72cjogxz 1342 1 In in IN cord-015369-72cjogxz 1342 2 allogeneic allogeneic NN cord-015369-72cjogxz 1342 3 transplants transplant NNS cord-015369-72cjogxz 1342 4 , , , cord-015369-72cjogxz 1342 5 IL-1a IL-1a NNP cord-015369-72cjogxz 1342 6 and and CC cord-015369-72cjogxz 1342 7 IL-18 IL-18 NNP cord-015369-72cjogxz 1342 8 levels level NNS cord-015369-72cjogxz 1342 9 were be VBD cord-015369-72cjogxz 1342 10 similar similar JJ cord-015369-72cjogxz 1342 11 to to IN cord-015369-72cjogxz 1342 12 the the DT cord-015369-72cjogxz 1342 13 syngeneic syngeneic NNS cord-015369-72cjogxz 1342 14 . . . cord-015369-72cjogxz 1343 1 At at IN cord-015369-72cjogxz 1343 2 POD POD NNP cord-015369-72cjogxz 1343 3 7 7 CD cord-015369-72cjogxz 1343 4 , , , cord-015369-72cjogxz 1343 5 allogeneics allogeneic NNS cord-015369-72cjogxz 1343 6 expressed express VBD cord-015369-72cjogxz 1343 7 IL-1b IL-1b NNP cord-015369-72cjogxz 1343 8 at at IN cord-015369-72cjogxz 1343 9 6029 6029 CD cord-015369-72cjogxz 1343 10 pg pg NN cord-015369-72cjogxz 1343 11 / / SYM cord-015369-72cjogxz 1343 12 ml ml NN cord-015369-72cjogxz 1343 13 ( ( -LRB- cord-015369-72cjogxz 1343 14 > > NFP cord-015369-72cjogxz 1343 15 65.5 65.5 CD cord-015369-72cjogxz 1343 16 Â â NN cord-015369-72cjogxz 1343 17 ÁBC ÁBC NNP cord-015369-72cjogxz 1343 18 , , , cord-015369-72cjogxz 1343 19 SD SD NNP cord-015369-72cjogxz 1343 20 ¼ ¼ CD cord-015369-72cjogxz 1343 21 21.96 21.96 CD cord-015369-72cjogxz 1343 22 % % NN cord-015369-72cjogxz 1343 23 ) ) -RRB- cord-015369-72cjogxz 1343 24 , , , cord-015369-72cjogxz 1343 25 IL-6 IL-6 NNP cord-015369-72cjogxz 1343 26 at at IN cord-015369-72cjogxz 1343 27 3145 3145 CD cord-015369-72cjogxz 1343 28 pg/ pg/ NNS cord-015369-72cjogxz 1343 29 ml ml NN cord-015369-72cjogxz 1344 1 ( ( -LRB- cord-015369-72cjogxz 1344 2 > > NFP cord-015369-72cjogxz 1344 3 19.41 19.41 CD cord-015369-72cjogxz 1344 4 Â â NN cord-015369-72cjogxz 1344 5 ÁBC ÁBC NNP cord-015369-72cjogxz 1344 6 , , , cord-015369-72cjogxz 1344 7 SD SD NNP cord-015369-72cjogxz 1344 8 ¼ ¼ CD cord-015369-72cjogxz 1344 9 10.58 10.58 CD cord-015369-72cjogxz 1344 10 % % NN cord-015369-72cjogxz 1344 11 ) ) -RRB- cord-015369-72cjogxz 1344 12 and and CC cord-015369-72cjogxz 1344 13 GRO GRO NNP cord-015369-72cjogxz 1344 14 / / SYM cord-015369-72cjogxz 1344 15 KC KC NNP cord-015369-72cjogxz 1344 16 at at IN cord-015369-72cjogxz 1344 17 813 813 CD cord-015369-72cjogxz 1344 18 pg pg NN cord-015369-72cjogxz 1344 19 / / SYM cord-015369-72cjogxz 1344 20 ml ml NN cord-015369-72cjogxz 1345 1 ( ( -LRB- cord-015369-72cjogxz 1345 2 > > NFP cord-015369-72cjogxz 1345 3 15.8 15.8 CD cord-015369-72cjogxz 1345 4 Â Â NNP cord-015369-72cjogxz 1345 5 BC BC NNP cord-015369-72cjogxz 1345 6 , , , cord-015369-72cjogxz 1345 7 SD SD NNP cord-015369-72cjogxz 1345 8 ¼ ¼ CD cord-015369-72cjogxz 1345 9 15.59 15.59 CD cord-015369-72cjogxz 1345 10 % % NN cord-015369-72cjogxz 1345 11 ) ) -RRB- cord-015369-72cjogxz 1345 12 . . . cord-015369-72cjogxz 1346 1 Conclusions conclusion NNS cord-015369-72cjogxz 1346 2 . . . cord-015369-72cjogxz 1347 1 Most Most JJS cord-015369-72cjogxz 1347 2 prevalent prevalent JJ cord-015369-72cjogxz 1347 3 cytokines cytokine NNS cord-015369-72cjogxz 1347 4 at at IN cord-015369-72cjogxz 1347 5 different different JJ cord-015369-72cjogxz 1347 6 time time NN cord-015369-72cjogxz 1347 7 points point NNS cord-015369-72cjogxz 1347 8 during during IN cord-015369-72cjogxz 1347 9 skin skin NN cord-015369-72cjogxz 1347 10 rejection rejection NN cord-015369-72cjogxz 1347 11 were be VBD cord-015369-72cjogxz 1347 12 identified identify VBN cord-015369-72cjogxz 1347 13 . . . cord-015369-72cjogxz 1348 1 This this DT cord-015369-72cjogxz 1348 2 analysis analysis NN cord-015369-72cjogxz 1348 3 helps help VBZ cord-015369-72cjogxz 1348 4 understand understand VB cord-015369-72cjogxz 1348 5 the the DT cord-015369-72cjogxz 1348 6 pathogenesis pathogenesis NN cord-015369-72cjogxz 1348 7 , , , cord-015369-72cjogxz 1348 8 provides provide VBZ cord-015369-72cjogxz 1348 9 a a DT cord-015369-72cjogxz 1348 10 basis basis NN cord-015369-72cjogxz 1348 11 for for IN cord-015369-72cjogxz 1348 12 early early JJ cord-015369-72cjogxz 1348 13 detection detection NN cord-015369-72cjogxz 1348 14 of of IN cord-015369-72cjogxz 1348 15 rejection rejection NN cord-015369-72cjogxz 1348 16 , , , cord-015369-72cjogxz 1348 17 and and CC cord-015369-72cjogxz 1348 18 identifies identify VBZ cord-015369-72cjogxz 1348 19 novel novel JJ cord-015369-72cjogxz 1348 20 targets target NNS cord-015369-72cjogxz 1348 21 for for IN cord-015369-72cjogxz 1348 22 therapeutic therapeutic JJ cord-015369-72cjogxz 1348 23 intervention intervention NN cord-015369-72cjogxz 1348 24 . . . cord-015369-72cjogxz 1349 1 Disclosure disclosure NN cord-015369-72cjogxz 1349 2 . . . cord-015369-72cjogxz 1350 1 None none NN cord-015369-72cjogxz 1350 2 . . . cord-015369-72cjogxz 1351 1 Project project NN cord-015369-72cjogxz 1351 2 funded fund VBN cord-015369-72cjogxz 1351 3 by by IN cord-015369-72cjogxz 1351 4 the the DT cord-015369-72cjogxz 1351 5 Austrian Austrian NNP cord-015369-72cjogxz 1351 6 Science Science NNP cord-015369-72cjogxz 1351 7 Fund Fund NNP cord-015369-72cjogxz 1351 8 ( ( -LRB- cord-015369-72cjogxz 1351 9 FWF FWF NNP cord-015369-72cjogxz 1351 10 ) ) -RRB- cord-015369-72cjogxz 1351 11 . . . cord-015369-72cjogxz 1352 1 Targeting target VBG cord-015369-72cjogxz 1352 2 E e NN cord-015369-72cjogxz 1352 3 - - : cord-015369-72cjogxz 1352 4 and and CC cord-015369-72cjogxz 1352 5 P p NN cord-015369-72cjogxz 1352 6 - - HYPH cord-015369-72cjogxz 1352 7 selectin selectin NNP cord-015369-72cjogxz 1352 8 for for IN cord-015369-72cjogxz 1352 9 treatment treatment NN cord-015369-72cjogxz 1352 10 of of IN cord-015369-72cjogxz 1352 11 skin skin NN cord-015369-72cjogxz 1352 12 rejection rejection NN cord-015369-72cjogxz 1352 13 in in IN cord-015369-72cjogxz 1352 14 limb limb NN cord-015369-72cjogxz 1352 15 transplantation transplantation NN cord-015369-72cjogxz 1352 16 Background Background NNP cord-015369-72cjogxz 1352 17 . . . cord-015369-72cjogxz 1353 1 Skin skin NN cord-015369-72cjogxz 1353 2 rejection rejection NN cord-015369-72cjogxz 1353 3 episodes episode NNS cord-015369-72cjogxz 1353 4 are be VBP cord-015369-72cjogxz 1353 5 a a DT cord-015369-72cjogxz 1353 6 frequent frequent JJ cord-015369-72cjogxz 1353 7 problem problem NN cord-015369-72cjogxz 1353 8 seen see VBN cord-015369-72cjogxz 1353 9 after after IN cord-015369-72cjogxz 1353 10 human human JJ cord-015369-72cjogxz 1353 11 hand hand NN cord-015369-72cjogxz 1353 12 transplantation transplantation NN cord-015369-72cjogxz 1353 13 . . . cord-015369-72cjogxz 1354 1 We -PRON- PRP cord-015369-72cjogxz 1354 2 therefore therefore RB cord-015369-72cjogxz 1354 3 investigate investigate VBP cord-015369-72cjogxz 1354 4 the the DT cord-015369-72cjogxz 1354 5 expression expression NN cord-015369-72cjogxz 1354 6 of of IN cord-015369-72cjogxz 1354 7 E e NN cord-015369-72cjogxz 1354 8 - - HYPH cord-015369-72cjogxz 1354 9 þP þP NNP cord-015369-72cjogxz 1354 10 - - HYPH cord-015369-72cjogxz 1354 11 Selectin Selectin NNP cord-015369-72cjogxz 1354 12 in in IN cord-015369-72cjogxz 1354 13 skin skin NN cord-015369-72cjogxz 1354 14 of of IN cord-015369-72cjogxz 1354 15 human human JJ cord-015369-72cjogxz 1354 16 hand hand NN cord-015369-72cjogxz 1354 17 allografts allograft NNS cord-015369-72cjogxz 1354 18 and and CC cord-015369-72cjogxz 1354 19 the the DT cord-015369-72cjogxz 1354 20 effect effect NN cord-015369-72cjogxz 1354 21 of of IN cord-015369-72cjogxz 1354 22 Efomycine Efomycine NNP cord-015369-72cjogxz 1354 23 - - HYPH cord-015369-72cjogxz 1354 24 M M NNP cord-015369-72cjogxz 1354 25 , , , cord-015369-72cjogxz 1354 26 a a DT cord-015369-72cjogxz 1354 27 special special JJ cord-015369-72cjogxz 1354 28 inhibitor inhibitor NN cord-015369-72cjogxz 1354 29 of of IN cord-015369-72cjogxz 1354 30 selectin selectin NNP cord-015369-72cjogxz 1354 31 in in IN cord-015369-72cjogxz 1354 32 a a DT cord-015369-72cjogxz 1354 33 rat rat NN cord-015369-72cjogxz 1354 34 limb limb NN cord-015369-72cjogxz 1354 35 - - HYPH cord-015369-72cjogxz 1354 36 transplant transplant NN cord-015369-72cjogxz 1354 37 - - HYPH cord-015369-72cjogxz 1354 38 model model NN cord-015369-72cjogxz 1354 39 . . . cord-015369-72cjogxz 1355 1 Methods method NNS cord-015369-72cjogxz 1355 2 . . . cord-015369-72cjogxz 1356 1 104 104 CD cord-015369-72cjogxz 1356 2 skin skin NN cord-015369-72cjogxz 1356 3 biopsies biopsy NNS cord-015369-72cjogxz 1356 4 from from IN cord-015369-72cjogxz 1356 5 three three CD cord-015369-72cjogxz 1356 6 bilateral bilateral JJ cord-015369-72cjogxz 1356 7 hand hand NN cord-015369-72cjogxz 1356 8 transplants transplant NNS cord-015369-72cjogxz 1356 9 were be VBD cord-015369-72cjogxz 1356 10 assessed assess VBN cord-015369-72cjogxz 1356 11 by by IN cord-015369-72cjogxz 1356 12 H&E H&E NNP cord-015369-72cjogxz 1356 13 - - HYPH cord-015369-72cjogxz 1356 14 histology histology NN cord-015369-72cjogxz 1356 15 and and CC cord-015369-72cjogxz 1356 16 immunohistochemistry immunohistochemistry JJ cord-015369-72cjogxz 1356 17 ( ( -LRB- cord-015369-72cjogxz 1356 18 anti anti JJ cord-015369-72cjogxz 1356 19 - - JJ cord-015369-72cjogxz 1356 20 E e JJ cord-015369-72cjogxz 1356 21 - - HYPH cord-015369-72cjogxz 1356 22 þP þp JJ cord-015369-72cjogxz 1356 23 - - HYPH cord-015369-72cjogxz 1356 24 Selectin selectin NN cord-015369-72cjogxz 1356 25 - - HYPH cord-015369-72cjogxz 1356 26 antibody antibody NN cord-015369-72cjogxz 1356 27 ) ) -RRB- cord-015369-72cjogxz 1356 28 . . . cord-015369-72cjogxz 1357 1 Efomycine Efomycine NNP cord-015369-72cjogxz 1357 2 - - HYPH cord-015369-72cjogxz 1357 3 M M NNP cord-015369-72cjogxz 1357 4 was be VBD cord-015369-72cjogxz 1357 5 investigated investigate VBN cord-015369-72cjogxz 1357 6 for for IN cord-015369-72cjogxz 1357 7 its -PRON- PRP$ cord-015369-72cjogxz 1357 8 effect effect NN cord-015369-72cjogxz 1357 9 on on IN cord-015369-72cjogxz 1357 10 skin skin NN cord-015369-72cjogxz 1357 11 rejection rejection NN cord-015369-72cjogxz 1357 12 in in IN cord-015369-72cjogxz 1357 13 an an DT cord-015369-72cjogxz 1357 14 orthotopic orthotopic JJ cord-015369-72cjogxz 1357 15 rat rat NN cord-015369-72cjogxz 1357 16 hind hind NN cord-015369-72cjogxz 1357 17 - - HYPH cord-015369-72cjogxz 1357 18 limb limb NN cord-015369-72cjogxz 1357 19 - - HYPH cord-015369-72cjogxz 1357 20 allotransplant allotransplant JJ cord-015369-72cjogxz 1357 21 - - HYPH cord-015369-72cjogxz 1357 22 model model NN cord-015369-72cjogxz 1357 23 ( ( -LRB- cord-015369-72cjogxz 1357 24 BN BN NNP cord-015369-72cjogxz 1357 25 - - HYPH cord-015369-72cjogxz 1357 26 LEW LEW NNP cord-015369-72cjogxz 1357 27 ) ) -RRB- cord-015369-72cjogxz 1357 28 . . . cord-015369-72cjogxz 1358 1 Animals animal NNS cord-015369-72cjogxz 1358 2 received receive VBD cord-015369-72cjogxz 1358 3 either either CC cord-015369-72cjogxz 1358 4 Efomycine Efomycine NNP cord-015369-72cjogxz 1358 5 - - HYPH cord-015369-72cjogxz 1358 6 M m NN cord-015369-72cjogxz 1358 7 alone alone RB cord-015369-72cjogxz 1358 8 ( ( -LRB- cord-015369-72cjogxz 1358 9 5 5 CD cord-015369-72cjogxz 1358 10 mg mg NNP cord-015369-72cjogxz 1358 11 / / SYM cord-015369-72cjogxz 1358 12 kg kg NNP cord-015369-72cjogxz 1358 13 / / SYM cord-015369-72cjogxz 1358 14 weekly weekly JJ cord-015369-72cjogxz 1358 15 s.c s.c NNP cord-015369-72cjogxz 1358 16 . . NNP cord-015369-72cjogxz 1358 17 into into IN cord-015369-72cjogxz 1358 18 the the DT cord-015369-72cjogxz 1358 19 graft graft NN cord-015369-72cjogxz 1358 20 ) ) -RRB- cord-015369-72cjogxz 1358 21 or or CC cord-015369-72cjogxz 1358 22 in in IN cord-015369-72cjogxz 1358 23 combination combination NN cord-015369-72cjogxz 1358 24 with with IN cord-015369-72cjogxz 1358 25 ALS ALS NNP cord-015369-72cjogxz 1358 26 ( ( -LRB- cord-015369-72cjogxz 1358 27 0.5 0.5 CD cord-015369-72cjogxz 1358 28 ml ml NN cord-015369-72cjogxz 1358 29 , , , cord-015369-72cjogxz 1358 30 pod0 pod0 NN cord-015369-72cjogxz 1358 31 þ þ CD cord-015369-72cjogxz 1358 32 3 3 CD cord-015369-72cjogxz 1358 33 ) ) -RRB- cord-015369-72cjogxz 1358 34 and and CC cord-015369-72cjogxz 1358 35 tacrolimus tacrolimus NNP cord-015369-72cjogxz 1358 36 ( ( -LRB- cord-015369-72cjogxz 1358 37 0.3 0.3 CD cord-015369-72cjogxz 1358 38 mg/ mg/ NNP cord-015369-72cjogxz 1358 39 kg kg NNP cord-015369-72cjogxz 1358 40 / / SYM cord-015369-72cjogxz 1358 41 day day NN cord-015369-72cjogxz 1358 42 for for IN cord-015369-72cjogxz 1358 43 50 50 CD cord-015369-72cjogxz 1358 44 days day NNS cord-015369-72cjogxz 1358 45 ) ) -RRB- cord-015369-72cjogxz 1358 46 . . . cord-015369-72cjogxz 1359 1 Untreated untreated JJ cord-015369-72cjogxz 1359 2 animals animal NNS cord-015369-72cjogxz 1359 3 and and CC cord-015369-72cjogxz 1359 4 animals animal NNS cord-015369-72cjogxz 1359 5 receiving receive VBG cord-015369-72cjogxz 1359 6 ALS ALS NNP cord-015369-72cjogxz 1359 7 þ þ NNP cord-015369-72cjogxz 1359 8 tacrolimus tacrolimus NN cord-015369-72cjogxz 1359 9 alone alone RB cord-015369-72cjogxz 1359 10 served serve VBD cord-015369-72cjogxz 1359 11 as as IN cord-015369-72cjogxz 1359 12 controls control NNS cord-015369-72cjogxz 1359 13 . . . cord-015369-72cjogxz 1360 1 Skin skin NN cord-015369-72cjogxz 1360 2 rejection rejection NN cord-015369-72cjogxz 1360 3 was be VBD cord-015369-72cjogxz 1360 4 assessed assess VBN cord-015369-72cjogxz 1360 5 by by IN cord-015369-72cjogxz 1360 6 daily daily JJ cord-015369-72cjogxz 1360 7 inspection inspection NN cord-015369-72cjogxz 1360 8 and and CC cord-015369-72cjogxz 1360 9 HE he NN cord-015369-72cjogxz 1360 10 - - HYPH cord-015369-72cjogxz 1360 11 histology histology NN cord-015369-72cjogxz 1360 12 . . . cord-015369-72cjogxz 1361 1 Results result NNS cord-015369-72cjogxz 1361 2 . . . cord-015369-72cjogxz 1362 1 E e LS cord-015369-72cjogxz 1362 2 - - : cord-015369-72cjogxz 1362 3 and and CC cord-015369-72cjogxz 1362 4 P P NNP cord-015369-72cjogxz 1362 5 - - : cord-015369-72cjogxz 1362 6 Selectin Selectin NNP cord-015369-72cjogxz 1362 7 expression expression NN cord-015369-72cjogxz 1362 8 in in IN cord-015369-72cjogxz 1362 9 the the DT cord-015369-72cjogxz 1362 10 vascular vascular JJ cord-015369-72cjogxz 1362 11 endothelium endothelium NN cord-015369-72cjogxz 1362 12 were be VBD cord-015369-72cjogxz 1362 13 significantly significantly RB cord-015369-72cjogxz 1362 14 upregulated upregulate VBN cord-015369-72cjogxz 1362 15 and and CC cord-015369-72cjogxz 1362 16 correlated correlate VBN cord-015369-72cjogxz 1362 17 well well RB cord-015369-72cjogxz 1362 18 with with IN cord-015369-72cjogxz 1362 19 severity severity NN cord-015369-72cjogxz 1362 20 of of IN cord-015369-72cjogxz 1362 21 rejection rejection NN cord-015369-72cjogxz 1362 22 in in IN cord-015369-72cjogxz 1362 23 human human JJ cord-015369-72cjogxz 1362 24 hand hand NN cord-015369-72cjogxz 1362 25 allografts allograft NNS cord-015369-72cjogxz 1362 26 . . . cord-015369-72cjogxz 1363 1 In in IN cord-015369-72cjogxz 1363 2 the the DT cord-015369-72cjogxz 1363 3 experimental experimental JJ cord-015369-72cjogxz 1363 4 trial trial NN cord-015369-72cjogxz 1363 5 animals animal NNS cord-015369-72cjogxz 1363 6 receiving receive VBG cord-015369-72cjogxz 1363 7 Efomycine Efomycine NNP cord-015369-72cjogxz 1363 8 - - HYPH cord-015369-72cjogxz 1363 9 M M NNP cord-015369-72cjogxz 1363 10 alone alone RB cord-015369-72cjogxz 1363 11 rejected reject VBD cord-015369-72cjogxz 1363 12 on on IN cord-015369-72cjogxz 1363 13 day day NN cord-015369-72cjogxz 1363 14 7 7 CD cord-015369-72cjogxz 1363 15 AE AE NNP cord-015369-72cjogxz 1363 16 1 1 CD cord-015369-72cjogxz 1363 17 . . . cord-015369-72cjogxz 1364 1 These these DT cord-015369-72cjogxz 1364 2 animals animal NNS cord-015369-72cjogxz 1364 3 did do VBD cord-015369-72cjogxz 1364 4 n't not RB cord-015369-72cjogxz 1364 5 show show VB cord-015369-72cjogxz 1364 6 prolongation prolongation NN cord-015369-72cjogxz 1364 7 of of IN cord-015369-72cjogxz 1364 8 graft graft NN cord-015369-72cjogxz 1364 9 survival survival NN cord-015369-72cjogxz 1364 10 in in IN cord-015369-72cjogxz 1364 11 contrast contrast NN cord-015369-72cjogxz 1364 12 to to IN cord-015369-72cjogxz 1364 13 untreated untreated JJ cord-015369-72cjogxz 1364 14 animals animal NNS cord-015369-72cjogxz 1364 15 . . . cord-015369-72cjogxz 1365 1 Animals animal NNS cord-015369-72cjogxz 1365 2 receiving receive VBG cord-015369-72cjogxz 1365 3 ALS als NN cord-015369-72cjogxz 1365 4 and and CC cord-015369-72cjogxz 1365 5 tacrolimus tacrolimus NN cord-015369-72cjogxz 1365 6 rejected reject VBD cord-015369-72cjogxz 1365 7 on on IN cord-015369-72cjogxz 1365 8 pod pod NN cord-015369-72cjogxz 1365 9 61 61 CD cord-015369-72cjogxz 1365 10 AE AE NNP cord-015369-72cjogxz 1365 11 2 2 CD cord-015369-72cjogxz 1365 12 and and CC cord-015369-72cjogxz 1365 13 histology histology NN cord-015369-72cjogxz 1366 1 showed show VBD cord-015369-72cjogxz 1366 2 necrosis necrosis NN cord-015369-72cjogxz 1366 3 and and CC cord-015369-72cjogxz 1366 4 massive massive JJ cord-015369-72cjogxz 1366 5 infiltration infiltration NN cord-015369-72cjogxz 1366 6 of of IN cord-015369-72cjogxz 1366 7 lymphocytes lymphocyte NNS cord-015369-72cjogxz 1366 8 in in IN cord-015369-72cjogxz 1366 9 all all DT cord-015369-72cjogxz 1366 10 tissues tissue NNS cord-015369-72cjogxz 1366 11 . . . cord-015369-72cjogxz 1367 1 Additional additional JJ cord-015369-72cjogxz 1367 2 treatment treatment NN cord-015369-72cjogxz 1367 3 with with IN cord-015369-72cjogxz 1367 4 Efomycine Efomycine NNP cord-015369-72cjogxz 1367 5 - - HYPH cord-015369-72cjogxz 1367 6 M M NNP cord-015369-72cjogxz 1367 7 resulted result VBD cord-015369-72cjogxz 1367 8 in in IN cord-015369-72cjogxz 1367 9 long long JJ cord-015369-72cjogxz 1367 10 term term NN cord-015369-72cjogxz 1367 11 ( ( -LRB- cord-015369-72cjogxz 1367 12 150 150 CD cord-015369-72cjogxz 1367 13 days day NNS cord-015369-72cjogxz 1367 14 ) ) -RRB- cord-015369-72cjogxz 1367 15 allograft allograft NN cord-015369-72cjogxz 1367 16 survival survival NN cord-015369-72cjogxz 1367 17 . . . cord-015369-72cjogxz 1368 1 Histology histology NN cord-015369-72cjogxz 1368 2 on on IN cord-015369-72cjogxz 1368 3 day day NN cord-015369-72cjogxz 1368 4 150 150 CD cord-015369-72cjogxz 1368 5 showed show VBD cord-015369-72cjogxz 1368 6 a a DT cord-015369-72cjogxz 1368 7 lymphocytic lymphocytic JJ cord-015369-72cjogxz 1368 8 infiltrate infiltrate NN cord-015369-72cjogxz 1368 9 in in IN cord-015369-72cjogxz 1368 10 the the DT cord-015369-72cjogxz 1368 11 dermis dermis NN cord-015369-72cjogxz 1368 12 and and CC cord-015369-72cjogxz 1368 13 epidermis epidermis NN cord-015369-72cjogxz 1368 14 and and CC cord-015369-72cjogxz 1368 15 a a DT cord-015369-72cjogxz 1368 16 myointimal myointimal JJ cord-015369-72cjogxz 1368 17 proliferation proliferation NN cord-015369-72cjogxz 1368 18 consistent consistent JJ cord-015369-72cjogxz 1368 19 with with IN cord-015369-72cjogxz 1368 20 rejection rejection NN cord-015369-72cjogxz 1368 21 grade grade NN cord-015369-72cjogxz 1368 22 2 2 CD cord-015369-72cjogxz 1368 23 . . . cord-015369-72cjogxz 1369 1 Conclusions conclusion NNS cord-015369-72cjogxz 1369 2 . . . cord-015369-72cjogxz 1370 1 Selectins selectin NNS cord-015369-72cjogxz 1370 2 are be VBP cord-015369-72cjogxz 1370 3 upregulated upregulate VBN cord-015369-72cjogxz 1370 4 upon upon IN cord-015369-72cjogxz 1370 5 skin skin NN cord-015369-72cjogxz 1370 6 rejection rejection NN cord-015369-72cjogxz 1370 7 after after IN cord-015369-72cjogxz 1370 8 human human JJ cord-015369-72cjogxz 1370 9 hand hand NN cord-015369-72cjogxz 1370 10 transplantation transplantation NN cord-015369-72cjogxz 1370 11 . . . cord-015369-72cjogxz 1371 1 Local local JJ cord-015369-72cjogxz 1371 2 administration administration NN cord-015369-72cjogxz 1371 3 of of IN cord-015369-72cjogxz 1371 4 a a DT cord-015369-72cjogxz 1371 5 Selectin Selectin NNP cord-015369-72cjogxz 1371 6 - - HYPH cord-015369-72cjogxz 1371 7 blocker blocker NN cord-015369-72cjogxz 1371 8 in in IN cord-015369-72cjogxz 1371 9 combination combination NN cord-015369-72cjogxz 1371 10 with with IN cord-015369-72cjogxz 1371 11 ALS ALS NNP cord-015369-72cjogxz 1371 12 þ þ NNP cord-015369-72cjogxz 1371 13 tacrolimus tacrolimus NN cord-015369-72cjogxz 1371 14 results result VBZ cord-015369-72cjogxz 1371 15 in in IN cord-015369-72cjogxz 1371 16 significant significant JJ cord-015369-72cjogxz 1371 17 prolongation prolongation NN cord-015369-72cjogxz 1371 18 of of IN cord-015369-72cjogxz 1371 19 graft graft NN cord-015369-72cjogxz 1371 20 survival survival NN cord-015369-72cjogxz 1371 21 but but CC cord-015369-72cjogxz 1371 22 does do VBZ cord-015369-72cjogxz 1371 23 n't not RB cord-015369-72cjogxz 1371 24 prevent prevent VB cord-015369-72cjogxz 1371 25 chronic chronic JJ cord-015369-72cjogxz 1371 26 rejection rejection NN cord-015369-72cjogxz 1371 27 in in IN cord-015369-72cjogxz 1371 28 a a DT cord-015369-72cjogxz 1371 29 rat rat NN cord-015369-72cjogxz 1371 30 limb limb NN cord-015369-72cjogxz 1371 31 - - HYPH cord-015369-72cjogxz 1371 32 transplant transplant NN cord-015369-72cjogxz 1371 33 - - HYPH cord-015369-72cjogxz 1371 34 model model NN cord-015369-72cjogxz 1371 35 . . . cord-015369-72cjogxz 1372 1 Xenotransplantation xenotransplantation NN cord-015369-72cjogxz 1372 2 of of IN cord-015369-72cjogxz 1372 3 microencapsulated microencapsulate VBN cord-015369-72cjogxz 1372 4 porcine porcine JJ cord-015369-72cjogxz 1372 5 islet islet NN cord-015369-72cjogxz 1372 6 cells cell NNS cord-015369-72cjogxz 1372 7 in in IN cord-015369-72cjogxz 1372 8 diabetic diabetic JJ cord-015369-72cjogxz 1372 9 rats rat NNS cord-015369-72cjogxz 1372 10 Background Background NNP cord-015369-72cjogxz 1372 11 . . . cord-015369-72cjogxz 1373 1 Xenotransplantation xenotransplantation NN cord-015369-72cjogxz 1373 2 of of IN cord-015369-72cjogxz 1373 3 microencapsulated microencapsulate VBN cord-015369-72cjogxz 1373 4 porcine porcine JJ cord-015369-72cjogxz 1373 5 islet islet NN cord-015369-72cjogxz 1373 6 cells cell NNS cord-015369-72cjogxz 1373 7 might may MD cord-015369-72cjogxz 1373 8 be be VB cord-015369-72cjogxz 1373 9 a a DT cord-015369-72cjogxz 1373 10 possibility possibility NN cord-015369-72cjogxz 1373 11 to to TO cord-015369-72cjogxz 1373 12 overcome overcome VB cord-015369-72cjogxz 1373 13 the the DT cord-015369-72cjogxz 1373 14 shortage shortage NN cord-015369-72cjogxz 1373 15 of of IN cord-015369-72cjogxz 1373 16 human human JJ cord-015369-72cjogxz 1373 17 donor donor NN cord-015369-72cjogxz 1373 18 organs organ NNS cord-015369-72cjogxz 1373 19 for for IN cord-015369-72cjogxz 1373 20 pancreas pancreas NN cord-015369-72cjogxz 1373 21 transplantation transplantation NN cord-015369-72cjogxz 1373 22 . . . cord-015369-72cjogxz 1374 1 Several several JJ cord-015369-72cjogxz 1374 2 materials material NNS cord-015369-72cjogxz 1374 3 for for IN cord-015369-72cjogxz 1374 4 microencapsulation microencapsulation NN cord-015369-72cjogxz 1374 5 of of IN cord-015369-72cjogxz 1374 6 cells cell NNS cord-015369-72cjogxz 1374 7 are be VBP cord-015369-72cjogxz 1374 8 described describe VBN cord-015369-72cjogxz 1374 9 in in IN cord-015369-72cjogxz 1374 10 literature literature NN cord-015369-72cjogxz 1374 11 which which WDT cord-015369-72cjogxz 1374 12 all all DT cord-015369-72cjogxz 1374 13 show show VBP cord-015369-72cjogxz 1374 14 severe severe JJ cord-015369-72cjogxz 1374 15 disadvantages disadvantage NNS cord-015369-72cjogxz 1374 16 . . . cord-015369-72cjogxz 1375 1 NaCS NaCS NNP cord-015369-72cjogxz 1375 2 is be VBZ cord-015369-72cjogxz 1375 3 easy easy JJ cord-015369-72cjogxz 1375 4 to to TO cord-015369-72cjogxz 1375 5 produce produce VB cord-015369-72cjogxz 1375 6 , , , cord-015369-72cjogxz 1375 7 does do VBZ cord-015369-72cjogxz 1375 8 not not RB cord-015369-72cjogxz 1375 9 show show VB cord-015369-72cjogxz 1375 10 any any DT cord-015369-72cjogxz 1375 11 cytotoxicity cytotoxicity NN cord-015369-72cjogxz 1375 12 and and CC cord-015369-72cjogxz 1375 13 cell cell NN cord-015369-72cjogxz 1375 14 lines line NNS cord-015369-72cjogxz 1375 15 survive survive VBP cord-015369-72cjogxz 1375 16 for for IN cord-015369-72cjogxz 1375 17 a a DT cord-015369-72cjogxz 1375 18 nearly nearly RB cord-015369-72cjogxz 1375 19 unlimited unlimited JJ cord-015369-72cjogxz 1375 20 time time NN cord-015369-72cjogxz 1375 21 - - HYPH cord-015369-72cjogxz 1375 22 spam spam NN cord-015369-72cjogxz 1375 23 after after IN cord-015369-72cjogxz 1375 24 microencapsulation microencapsulation NN cord-015369-72cjogxz 1375 25 . . . cord-015369-72cjogxz 1376 1 However however RB cord-015369-72cjogxz 1376 2 , , , cord-015369-72cjogxz 1376 3 this this DT cord-015369-72cjogxz 1376 4 material material NN cord-015369-72cjogxz 1376 5 has have VBZ cord-015369-72cjogxz 1376 6 not not RB cord-015369-72cjogxz 1376 7 been be VBN cord-015369-72cjogxz 1376 8 tested test VBN cord-015369-72cjogxz 1376 9 for for IN cord-015369-72cjogxz 1376 10 microencapsulation microencapsulation NN cord-015369-72cjogxz 1376 11 and and CC cord-015369-72cjogxz 1376 12 xenotransplantation xenotransplantation NN cord-015369-72cjogxz 1376 13 of of IN cord-015369-72cjogxz 1376 14 porcine porcine JJ cord-015369-72cjogxz 1376 15 islet islet NN cord-015369-72cjogxz 1376 16 cells cell NNS cord-015369-72cjogxz 1376 17 . . . cord-015369-72cjogxz 1377 1 Methods method NNS cord-015369-72cjogxz 1377 2 . . . cord-015369-72cjogxz 1378 1 Porcine porcine JJ cord-015369-72cjogxz 1378 2 islet islet NN cord-015369-72cjogxz 1378 3 cell cell NN cord-015369-72cjogxz 1378 4 isolation isolation NN cord-015369-72cjogxz 1378 5 and and CC cord-015369-72cjogxz 1378 6 purification purification NN cord-015369-72cjogxz 1378 7 was be VBD cord-015369-72cjogxz 1378 8 performed perform VBN cord-015369-72cjogxz 1378 9 according accord VBG cord-015369-72cjogxz 1378 10 to to IN cord-015369-72cjogxz 1378 11 a a DT cord-015369-72cjogxz 1378 12 newly newly RB cord-015369-72cjogxz 1378 13 modified modify VBN cord-015369-72cjogxz 1378 14 Ricordi Ricordi NNP cord-015369-72cjogxz 1378 15 method method NN cord-015369-72cjogxz 1378 16 and and CC cord-015369-72cjogxz 1378 17 microencapsulated microencapsulate VBN cord-015369-72cjogxz 1378 18 with with IN cord-015369-72cjogxz 1378 19 NaCS NaCS NNP cord-015369-72cjogxz 1378 20 . . . cord-015369-72cjogxz 1379 1 Diabetes diabetes NN cord-015369-72cjogxz 1379 2 was be VBD cord-015369-72cjogxz 1379 3 induced induce VBN cord-015369-72cjogxz 1379 4 in in IN cord-015369-72cjogxz 1379 5 Sprague Sprague NNP cord-015369-72cjogxz 1379 6 Dawley Dawley NNP cord-015369-72cjogxz 1379 7 rats rat NNS cord-015369-72cjogxz 1379 8 by by IN cord-015369-72cjogxz 1379 9 intraperitoneal intraperitoneal JJ cord-015369-72cjogxz 1379 10 injection injection NN cord-015369-72cjogxz 1379 11 of of IN cord-015369-72cjogxz 1379 12 STZ STZ NNP cord-015369-72cjogxz 1379 13 . . . cord-015369-72cjogxz 1380 1 Microencapsulated microencapsulated JJ cord-015369-72cjogxz 1380 2 porcine porcine JJ cord-015369-72cjogxz 1380 3 islet islet NN cord-015369-72cjogxz 1380 4 cells cell NNS cord-015369-72cjogxz 1380 5 were be VBD cord-015369-72cjogxz 1380 6 transplanted transplant VBN cord-015369-72cjogxz 1380 7 under under IN cord-015369-72cjogxz 1380 8 the the DT cord-015369-72cjogxz 1380 9 kidney kidney NN cord-015369-72cjogxz 1380 10 capsule capsule NN cord-015369-72cjogxz 1380 11 of of IN cord-015369-72cjogxz 1380 12 the the DT cord-015369-72cjogxz 1380 13 animals animal NNS cord-015369-72cjogxz 1380 14 . . . cord-015369-72cjogxz 1381 1 Blood blood NN cord-015369-72cjogxz 1381 2 sugar sugar NN cord-015369-72cjogxz 1381 3 levels level NNS cord-015369-72cjogxz 1381 4 were be VBD cord-015369-72cjogxz 1381 5 monitored monitor VBN cord-015369-72cjogxz 1381 6 on on IN cord-015369-72cjogxz 1381 7 a a DT cord-015369-72cjogxz 1381 8 weekly weekly JJ cord-015369-72cjogxz 1381 9 basis basis NN cord-015369-72cjogxz 1381 10 , , , cord-015369-72cjogxz 1381 11 porcine porcine JJ cord-015369-72cjogxz 1381 12 C C NNP cord-015369-72cjogxz 1381 13 - - HYPH cord-015369-72cjogxz 1381 14 Peptide Peptide NNP cord-015369-72cjogxz 1381 15 levels level NNS cord-015369-72cjogxz 1381 16 and and CC cord-015369-72cjogxz 1381 17 insulin insulin NN cord-015369-72cjogxz 1381 18 levels level NNS cord-015369-72cjogxz 1381 19 were be VBD cord-015369-72cjogxz 1381 20 measured measure VBN cord-015369-72cjogxz 1381 21 using use VBG cord-015369-72cjogxz 1381 22 ELISA ELISA NNP cord-015369-72cjogxz 1381 23 . . . cord-015369-72cjogxz 1382 1 After after IN cord-015369-72cjogxz 1382 2 4 4 CD cord-015369-72cjogxz 1382 3 months month NNS cord-015369-72cjogxz 1382 4 , , , cord-015369-72cjogxz 1382 5 the the DT cord-015369-72cjogxz 1382 6 animals animal NNS cord-015369-72cjogxz 1382 7 were be VBD cord-015369-72cjogxz 1382 8 sacrificed sacrifice VBN cord-015369-72cjogxz 1382 9 , , , cord-015369-72cjogxz 1382 10 the the DT cord-015369-72cjogxz 1382 11 kidney kidney NN cord-015369-72cjogxz 1382 12 containing contain VBG cord-015369-72cjogxz 1382 13 the the DT cord-015369-72cjogxz 1382 14 microencapsulated microencapsulate VBN cord-015369-72cjogxz 1382 15 porcine porcine JJ cord-015369-72cjogxz 1382 16 islet islet NN cord-015369-72cjogxz 1382 17 cells cell NNS cord-015369-72cjogxz 1382 18 was be VBD cord-015369-72cjogxz 1382 19 retrieved retrieve VBN cord-015369-72cjogxz 1382 20 and and CC cord-015369-72cjogxz 1382 21 processed process VBN cord-015369-72cjogxz 1382 22 for for IN cord-015369-72cjogxz 1382 23 histological histological JJ cord-015369-72cjogxz 1382 24 and and CC cord-015369-72cjogxz 1382 25 immunohistochemical immunohistochemical JJ cord-015369-72cjogxz 1382 26 examination examination NN cord-015369-72cjogxz 1382 27 . . . cord-015369-72cjogxz 1383 1 Results result NNS cord-015369-72cjogxz 1383 2 . . . cord-015369-72cjogxz 1384 1 After after IN cord-015369-72cjogxz 1384 2 xenotransplantation xenotransplantation NN cord-015369-72cjogxz 1384 3 of of IN cord-015369-72cjogxz 1384 4 microencapsulated microencapsulate VBN cord-015369-72cjogxz 1384 5 porcine porcine JJ cord-015369-72cjogxz 1384 6 islet islet NN cord-015369-72cjogxz 1384 7 cells cell NNS cord-015369-72cjogxz 1384 8 diabetes diabete NNS cord-015369-72cjogxz 1384 9 was be VBD cord-015369-72cjogxz 1384 10 reversed reverse VBN cord-015369-72cjogxz 1384 11 in in IN cord-015369-72cjogxz 1384 12 rats rat NNS cord-015369-72cjogxz 1384 13 . . . cord-015369-72cjogxz 1385 1 Animals animal NNS cord-015369-72cjogxz 1385 2 stayed stay VBD cord-015369-72cjogxz 1385 3 normoglycaemic normoglycaemic RB cord-015369-72cjogxz 1385 4 up up IN cord-015369-72cjogxz 1385 5 to to TO cord-015369-72cjogxz 1385 6 four four CD cord-015369-72cjogxz 1385 7 months month NNS cord-015369-72cjogxz 1385 8 . . . cord-015369-72cjogxz 1386 1 Functionality functionality NN cord-015369-72cjogxz 1386 2 of of IN cord-015369-72cjogxz 1386 3 transplanted transplant VBN cord-015369-72cjogxz 1386 4 porcine porcine JJ cord-015369-72cjogxz 1386 5 islet islet NN cord-015369-72cjogxz 1386 6 cells cell NNS cord-015369-72cjogxz 1386 7 was be VBD cord-015369-72cjogxz 1386 8 detected detect VBN cord-015369-72cjogxz 1386 9 by by IN cord-015369-72cjogxz 1386 10 insulin insulin NN cord-015369-72cjogxz 1386 11 measurement measurement NN cord-015369-72cjogxz 1386 12 and and CC cord-015369-72cjogxz 1386 13 detection detection NN cord-015369-72cjogxz 1386 14 of of IN cord-015369-72cjogxz 1386 15 C C NNP cord-015369-72cjogxz 1386 16 - - HYPH cord-015369-72cjogxz 1386 17 Peptide Peptide NNP cord-015369-72cjogxz 1386 18 . . . cord-015369-72cjogxz 1387 1 Viability viability NN cord-015369-72cjogxz 1387 2 of of IN cord-015369-72cjogxz 1387 3 microencapsulated microencapsulate VBN cord-015369-72cjogxz 1387 4 porcine porcine JJ cord-015369-72cjogxz 1387 5 islet islet NN cord-015369-72cjogxz 1387 6 cells cell NNS cord-015369-72cjogxz 1387 7 after after IN cord-015369-72cjogxz 1387 8 explantation explantation NN cord-015369-72cjogxz 1387 9 was be VBD cord-015369-72cjogxz 1387 10 proven prove VBN cord-015369-72cjogxz 1387 11 by by IN cord-015369-72cjogxz 1387 12 immunohistochemical immunohistochemical JJ cord-015369-72cjogxz 1387 13 viability viability NN cord-015369-72cjogxz 1387 14 stains stain NNS cord-015369-72cjogxz 1387 15 . . . cord-015369-72cjogxz 1388 1 Conclusions conclusion NNS cord-015369-72cjogxz 1388 2 . . . cord-015369-72cjogxz 1389 1 Rats rat NNS cord-015369-72cjogxz 1389 2 stayed stay VBD cord-015369-72cjogxz 1389 3 normoglycaemic normoglycaemic NNP cord-015369-72cjogxz 1389 4 until until IN cord-015369-72cjogxz 1389 5 the the DT cord-015369-72cjogxz 1389 6 end end NN cord-015369-72cjogxz 1389 7 of of IN cord-015369-72cjogxz 1389 8 the the DT cord-015369-72cjogxz 1389 9 study study NN cord-015369-72cjogxz 1389 10 period period NN cord-015369-72cjogxz 1389 11 . . . cord-015369-72cjogxz 1390 1 No no DT cord-015369-72cjogxz 1390 2 signs sign NNS cord-015369-72cjogxz 1390 3 of of IN cord-015369-72cjogxz 1390 4 fibrosis fibrosis NN cord-015369-72cjogxz 1390 5 could could MD cord-015369-72cjogxz 1390 6 be be VB cord-015369-72cjogxz 1390 7 detected detect VBN cord-015369-72cjogxz 1390 8 in in IN cord-015369-72cjogxz 1390 9 the the DT cord-015369-72cjogxz 1390 10 surrounding surround VBG cord-015369-72cjogxz 1390 11 tissue tissue NN cord-015369-72cjogxz 1390 12 . . . cord-015369-72cjogxz 1391 1 NaCS NaCS NNP cord-015369-72cjogxz 1391 2 seems seem VBZ cord-015369-72cjogxz 1391 3 to to TO cord-015369-72cjogxz 1391 4 be be VB cord-015369-72cjogxz 1391 5 a a DT cord-015369-72cjogxz 1391 6 promising promising JJ cord-015369-72cjogxz 1391 7 material material NN cord-015369-72cjogxz 1391 8 for for IN cord-015369-72cjogxz 1391 9 microencapsulation microencapsulation NN cord-015369-72cjogxz 1391 10 of of IN cord-015369-72cjogxz 1391 11 porcine porcine JJ cord-015369-72cjogxz 1391 12 islet islet NN cord-015369-72cjogxz 1391 13 cells cell NNS cord-015369-72cjogxz 1391 14 in in IN cord-015369-72cjogxz 1391 15 order order NN cord-015369-72cjogxz 1391 16 to to TO cord-015369-72cjogxz 1391 17 treat treat VB cord-015369-72cjogxz 1391 18 diabetes diabete NNS cord-015369-72cjogxz 1391 19 . . . cord-015369-72cjogxz 1392 1 Introducing introduce VBG cord-015369-72cjogxz 1392 2 the the DT cord-015369-72cjogxz 1392 3 cuff cuff NN cord-015369-72cjogxz 1392 4 technique technique NN cord-015369-72cjogxz 1392 5 for for IN cord-015369-72cjogxz 1392 6 hind hind JJ cord-015369-72cjogxz 1392 7 limb limb NN cord-015369-72cjogxz 1392 8 transplantation transplantation NN cord-015369-72cjogxz 1392 9 in in IN cord-015369-72cjogxz 1392 10 rats rat NNS cord-015369-72cjogxz 1392 11 Background Background NNP cord-015369-72cjogxz 1392 12 . . . cord-015369-72cjogxz 1393 1 Current current JJ cord-015369-72cjogxz 1393 2 models model NNS cord-015369-72cjogxz 1393 3 for for IN cord-015369-72cjogxz 1393 4 orthotopic orthotopic JJ cord-015369-72cjogxz 1393 5 hind hind JJ cord-015369-72cjogxz 1393 6 limb limb NN cord-015369-72cjogxz 1393 7 transplantation transplantation NN cord-015369-72cjogxz 1393 8 traditionally traditionally RB cord-015369-72cjogxz 1393 9 utilize utilize VBP cord-015369-72cjogxz 1393 10 a a DT cord-015369-72cjogxz 1393 11 time time NN cord-015369-72cjogxz 1393 12 - - HYPH cord-015369-72cjogxz 1393 13 consuming consume VBG cord-015369-72cjogxz 1393 14 , , , cord-015369-72cjogxz 1393 15 technically technically RB cord-015369-72cjogxz 1393 16 demanding demand VBG cord-015369-72cjogxz 1393 17 micro micro JJ cord-015369-72cjogxz 1393 18 - - JJ cord-015369-72cjogxz 1393 19 vascular vascular JJ cord-015369-72cjogxz 1393 20 suture suture NN cord-015369-72cjogxz 1393 21 technique technique NN cord-015369-72cjogxz 1393 22 for for IN cord-015369-72cjogxz 1393 23 vascular vascular JJ cord-015369-72cjogxz 1393 24 anastomoses anastomosis NNS cord-015369-72cjogxz 1393 25 . . . cord-015369-72cjogxz 1394 1 Our -PRON- PRP$ cord-015369-72cjogxz 1394 2 objective objective NN cord-015369-72cjogxz 1394 3 was be VBD cord-015369-72cjogxz 1394 4 to to TO cord-015369-72cjogxz 1394 5 introduce introduce VB cord-015369-72cjogxz 1394 6 a a DT cord-015369-72cjogxz 1394 7 new new JJ cord-015369-72cjogxz 1394 8 simplified simplified JJ cord-015369-72cjogxz 1394 9 vascular vascular NN cord-015369-72cjogxz 1394 10 ' ' '' cord-015369-72cjogxz 1394 11 ' ' `` cord-015369-72cjogxz 1394 12 cuff cuff NN cord-015369-72cjogxz 1394 13 technique technique NN cord-015369-72cjogxz 1394 14 ' ' '' cord-015369-72cjogxz 1394 15 ' ' '' cord-015369-72cjogxz 1394 16 which which WDT cord-015369-72cjogxz 1394 17 substantially substantially RB cord-015369-72cjogxz 1394 18 accelerates accelerate VBZ cord-015369-72cjogxz 1394 19 the the DT cord-015369-72cjogxz 1394 20 surgical surgical JJ cord-015369-72cjogxz 1394 21 procedure procedure NN cord-015369-72cjogxz 1394 22 and and CC cord-015369-72cjogxz 1394 23 is be VBZ cord-015369-72cjogxz 1394 24 well well RB cord-015369-72cjogxz 1394 25 suited suited JJ cord-015369-72cjogxz 1394 26 to to TO cord-015369-72cjogxz 1394 27 study study VB cord-015369-72cjogxz 1394 28 ischemia ischemia NN cord-015369-72cjogxz 1394 29 / / SYM cord-015369-72cjogxz 1394 30 reperfusion reperfusion NN cord-015369-72cjogxz 1394 31 injury injury NN cord-015369-72cjogxz 1394 32 in in IN cord-015369-72cjogxz 1394 33 Reconstructive Reconstructive NNP cord-015369-72cjogxz 1394 34 Transplantation Transplantation NNP cord-015369-72cjogxz 1394 35 . . . cord-015369-72cjogxz 1395 1 Methods method NNS cord-015369-72cjogxz 1395 2 . . . cord-015369-72cjogxz 1396 1 Syngenic Syngenic NNP cord-015369-72cjogxz 1396 2 hind hind NN cord-015369-72cjogxz 1396 3 limbs limb NNS cord-015369-72cjogxz 1396 4 were be VBD cord-015369-72cjogxz 1396 5 transplanted transplant VBN cord-015369-72cjogxz 1396 6 orthotopically orthotopically RB cord-015369-72cjogxz 1396 7 using use VBG cord-015369-72cjogxz 1396 8 Lewis Lewis NNP cord-015369-72cjogxz 1396 9 rats rat NNS cord-015369-72cjogxz 1396 10 employing employ VBG cord-015369-72cjogxz 1396 11 either either CC cord-015369-72cjogxz 1396 12 the the DT cord-015369-72cjogxz 1396 13 conventional conventional JJ cord-015369-72cjogxz 1396 14 microsuture microsuture NN cord-015369-72cjogxz 1396 15 technique technique NN cord-015369-72cjogxz 1396 16 ( ( -LRB- cord-015369-72cjogxz 1396 17 n n NNP cord-015369-72cjogxz 1396 18 ¼ ¼ NNP cord-015369-72cjogxz 1396 19 10 10 CD cord-015369-72cjogxz 1396 20 ) ) -RRB- cord-015369-72cjogxz 1396 21 or or CC cord-015369-72cjogxz 1396 22 the the DT cord-015369-72cjogxz 1396 23 new new JJ cord-015369-72cjogxz 1396 24 ' ' '' cord-015369-72cjogxz 1396 25 ' ' `` cord-015369-72cjogxz 1396 26 cuff cuff NN cord-015369-72cjogxz 1396 27 technique technique NN cord-015369-72cjogxz 1396 28 ' ' '' cord-015369-72cjogxz 1396 29 ' ' '' cord-015369-72cjogxz 1396 30 ( ( -LRB- cord-015369-72cjogxz 1396 31 n n NN cord-015369-72cjogxz 1396 32 ¼ ¼ NNP cord-015369-72cjogxz 1396 33 10 10 CD cord-015369-72cjogxz 1396 34 ) ) -RRB- cord-015369-72cjogxz 1396 35 for for IN cord-015369-72cjogxz 1396 36 vascular vascular JJ cord-015369-72cjogxz 1396 37 anastomosis anastomosis NN cord-015369-72cjogxz 1396 38 . . . cord-015369-72cjogxz 1397 1 Results result NNS cord-015369-72cjogxz 1397 2 . . . cord-015369-72cjogxz 1398 1 All all DT cord-015369-72cjogxz 1398 2 grafts graft NNS cord-015369-72cjogxz 1398 3 in in IN cord-015369-72cjogxz 1398 4 the the DT cord-015369-72cjogxz 1398 5 microsuture microsuture NN cord-015369-72cjogxz 1398 6 technique technique NN cord-015369-72cjogxz 1398 7 and and CC cord-015369-72cjogxz 1398 8 9 9 CD cord-015369-72cjogxz 1398 9 out out IN cord-015369-72cjogxz 1398 10 of of IN cord-015369-72cjogxz 1398 11 10 10 CD cord-015369-72cjogxz 1398 12 grafts graft NNS cord-015369-72cjogxz 1398 13 in in IN cord-015369-72cjogxz 1398 14 the the DT cord-015369-72cjogxz 1398 15 ' ' NN cord-015369-72cjogxz 1398 16 ' ' `` cord-015369-72cjogxz 1398 17 cuff cuff NN cord-015369-72cjogxz 1398 18 technique technique NN cord-015369-72cjogxz 1398 19 ' ' '' cord-015369-72cjogxz 1398 20 ' ' '' cord-015369-72cjogxz 1398 21 group group NN cord-015369-72cjogxz 1398 22 survived survive VBD cord-015369-72cjogxz 1398 23 the the DT cord-015369-72cjogxz 1398 24 endpoint endpoint NN cord-015369-72cjogxz 1398 25 of of IN cord-015369-72cjogxz 1398 26 the the DT cord-015369-72cjogxz 1398 27 study study NN cord-015369-72cjogxz 1398 28 ( ( -LRB- cord-015369-72cjogxz 1398 29 postoperative postoperative JJ cord-015369-72cjogxz 1398 30 day day NN cord-015369-72cjogxz 1398 31 10 10 CD cord-015369-72cjogxz 1398 32 ) ) -RRB- cord-015369-72cjogxz 1398 33 . . . cord-015369-72cjogxz 1399 1 Microangiography microangiography NN cord-015369-72cjogxz 1399 2 on on IN cord-015369-72cjogxz 1399 3 postoperative postoperative JJ cord-015369-72cjogxz 1399 4 day day NN cord-015369-72cjogxz 1399 5 10 10 CD cord-015369-72cjogxz 1399 6 showed show VBD cord-015369-72cjogxz 1399 7 no no DT cord-015369-72cjogxz 1399 8 stenosis stenosis NN cord-015369-72cjogxz 1399 9 or or CC cord-015369-72cjogxz 1399 10 occlusion occlusion NN cord-015369-72cjogxz 1399 11 of of IN cord-015369-72cjogxz 1399 12 anastomoses anastomosis NNS cord-015369-72cjogxz 1399 13 , , , cord-015369-72cjogxz 1399 14 skin skin NN cord-015369-72cjogxz 1399 15 and and CC cord-015369-72cjogxz 1399 16 muscle muscle NN cord-015369-72cjogxz 1399 17 histology histology NN cord-015369-72cjogxz 1399 18 demonstrated demonstrate VBD cord-015369-72cjogxz 1399 19 normal normal JJ cord-015369-72cjogxz 1399 20 appearing appear VBG cord-015369-72cjogxz 1399 21 tissues tissue NNS cord-015369-72cjogxz 1399 22 . . . cord-015369-72cjogxz 1400 1 Conclusions conclusion NNS cord-015369-72cjogxz 1400 2 . . . cord-015369-72cjogxz 1401 1 Our -PRON- PRP$ cord-015369-72cjogxz 1401 2 newly newly RB cord-015369-72cjogxz 1401 3 introduced introduce VBN cord-015369-72cjogxz 1401 4 cuff cuff NN cord-015369-72cjogxz 1401 5 technique technique NN cord-015369-72cjogxz 1401 6 enables enable VBZ cord-015369-72cjogxz 1401 7 for for IN cord-015369-72cjogxz 1401 8 significantly significantly RB cord-015369-72cjogxz 1401 9 reduced reduce VBN cord-015369-72cjogxz 1401 10 operating operating NN cord-015369-72cjogxz 1401 11 time time NN cord-015369-72cjogxz 1401 12 ( ( -LRB- cord-015369-72cjogxz 1401 13 cuff cuff NN cord-015369-72cjogxz 1401 14 group group NN cord-015369-72cjogxz 1401 15 : : : cord-015369-72cjogxz 1401 16 49 49 CD cord-015369-72cjogxz 1401 17 AE AE NNP cord-015369-72cjogxz 1401 18 5 5 CD cord-015369-72cjogxz 1401 19 min min NNP cord-015369-72cjogxz 1401 20 , , , cord-015369-72cjogxz 1401 21 vs vs IN cord-015369-72cjogxz 1401 22 conventional conventional JJ cord-015369-72cjogxz 1401 23 group group NN cord-015369-72cjogxz 1401 24 : : : cord-015369-72cjogxz 1401 25 118 118 CD cord-015369-72cjogxz 1401 26 AE AE NNP cord-015369-72cjogxz 1401 27 5 5 CD cord-015369-72cjogxz 1401 28 min min NNP cord-015369-72cjogxz 1401 29 ) ) -RRB- cord-015369-72cjogxz 1401 30 , , , cord-015369-72cjogxz 1401 31 low low JJ cord-015369-72cjogxz 1401 32 postoperative postoperative JJ cord-015369-72cjogxz 1401 33 morbidity morbidity NN cord-015369-72cjogxz 1401 34 and and CC cord-015369-72cjogxz 1401 35 mortality mortality NN cord-015369-72cjogxz 1401 36 ( ( -LRB- cord-015369-72cjogxz 1401 37 10 10 CD cord-015369-72cjogxz 1401 38 % % NN cord-015369-72cjogxz 1401 39 ) ) -RRB- cord-015369-72cjogxz 1401 40 and and CC cord-015369-72cjogxz 1401 41 excellent excellent JJ cord-015369-72cjogxz 1401 42 functional functional JJ cord-015369-72cjogxz 1401 43 results result NNS cord-015369-72cjogxz 1401 44 after after IN cord-015369-72cjogxz 1401 45 orthotopic orthotopic NNP cord-015369-72cjogxz 1401 46 hind hind JJ cord-015369-72cjogxz 1401 47 limb limb NN cord-015369-72cjogxz 1401 48 transplantation transplantation NN cord-015369-72cjogxz 1401 49 . . . cord-015369-72cjogxz 1402 1 A a DT cord-015369-72cjogxz 1402 2 quantitative quantitative JJ cord-015369-72cjogxz 1402 3 analysis analysis NN cord-015369-72cjogxz 1402 4 of of IN cord-015369-72cjogxz 1402 5 the the DT cord-015369-72cjogxz 1402 6 sensory sensory JJ cord-015369-72cjogxz 1402 7 and and CC cord-015369-72cjogxz 1402 8 sympathetic sympathetic JJ cord-015369-72cjogxz 1402 9 innervation innervation NN cord-015369-72cjogxz 1402 10 of of IN cord-015369-72cjogxz 1402 11 the the DT cord-015369-72cjogxz 1402 12 human human JJ cord-015369-72cjogxz 1402 13 pancreas pancreas NN cord-015369-72cjogxz 1403 1 The the DT cord-015369-72cjogxz 1403 2 delineation delineation NN cord-015369-72cjogxz 1403 3 of of IN cord-015369-72cjogxz 1403 4 pancreatic pancreatic JJ cord-015369-72cjogxz 1403 5 nerve nerve NN cord-015369-72cjogxz 1403 6 innervation innervation NN cord-015369-72cjogxz 1403 7 during during IN cord-015369-72cjogxz 1403 8 fetal fetal JJ cord-015369-72cjogxz 1403 9 life life NN cord-015369-72cjogxz 1403 10 may may MD cord-015369-72cjogxz 1403 11 contribute contribute VB cord-015369-72cjogxz 1403 12 to to IN cord-015369-72cjogxz 1403 13 our -PRON- PRP$ cord-015369-72cjogxz 1403 14 understanding understanding NN cord-015369-72cjogxz 1403 15 of of IN cord-015369-72cjogxz 1403 16 pancreatic pancreatic JJ cord-015369-72cjogxz 1403 17 pain pain NN cord-015369-72cjogxz 1403 18 modalities modality NNS cord-015369-72cjogxz 1403 19 after after IN cord-015369-72cjogxz 1403 20 birth birth NN cord-015369-72cjogxz 1403 21 . . . cord-015369-72cjogxz 1404 1 To to TO cord-015369-72cjogxz 1404 2 define define VB cord-015369-72cjogxz 1404 3 the the DT cord-015369-72cjogxz 1404 4 peripheral peripheral JJ cord-015369-72cjogxz 1404 5 sensory sensory JJ cord-015369-72cjogxz 1404 6 and and CC cord-015369-72cjogxz 1404 7 sympathetic sympathetic JJ cord-015369-72cjogxz 1404 8 fibers fiber NNS cord-015369-72cjogxz 1404 9 involved involve VBN cord-015369-72cjogxz 1404 10 in in IN cord-015369-72cjogxz 1404 11 transmitting transmit VBG cord-015369-72cjogxz 1404 12 and and CC cord-015369-72cjogxz 1404 13 modulating modulate VBG cord-015369-72cjogxz 1404 14 pancreatic pancreatic JJ cord-015369-72cjogxz 1404 15 pain pain NN cord-015369-72cjogxz 1404 16 , , , cord-015369-72cjogxz 1404 17 immunohistochemical immunohistochemical JJ cord-015369-72cjogxz 1404 18 detection detection NN cord-015369-72cjogxz 1404 19 was be VBD cord-015369-72cjogxz 1404 20 used use VBN cord-015369-72cjogxz 1404 21 to to TO cord-015369-72cjogxz 1404 22 examine examine VB cord-015369-72cjogxz 1404 23 the the DT cord-015369-72cjogxz 1404 24 sensory sensory JJ cord-015369-72cjogxz 1404 25 and and CC cord-015369-72cjogxz 1404 26 sympathetic sympathetic JJ cord-015369-72cjogxz 1404 27 innervation innervation NN cord-015369-72cjogxz 1404 28 of of IN cord-015369-72cjogxz 1404 29 the the DT cord-015369-72cjogxz 1404 30 head head NN cord-015369-72cjogxz 1404 31 , , , cord-015369-72cjogxz 1404 32 body body NN cord-015369-72cjogxz 1404 33 and and CC cord-015369-72cjogxz 1404 34 tail tail NN cord-015369-72cjogxz 1404 35 of of IN cord-015369-72cjogxz 1404 36 the the DT cord-015369-72cjogxz 1404 37 normal normal JJ cord-015369-72cjogxz 1404 38 human human JJ cord-015369-72cjogxz 1404 39 fetal fetal JJ cord-015369-72cjogxz 1404 40 pancreas pancrea NNS cord-015369-72cjogxz 1404 41 using use VBG cord-015369-72cjogxz 1404 42 specimens specimen NNS cord-015369-72cjogxz 1404 43 from from IN cord-015369-72cjogxz 1404 44 15 15 CD cord-015369-72cjogxz 1404 45 fetuses fetus NNS cord-015369-72cjogxz 1404 46 ( ( -LRB- cord-015369-72cjogxz 1404 47 13 13 CD cord-015369-72cjogxz 1404 48 - - SYM cord-015369-72cjogxz 1404 49 36 36 CD cord-015369-72cjogxz 1404 50 weeks week NNS cord-015369-72cjogxz 1404 51 of of IN cord-015369-72cjogxz 1404 52 gestation gestation NN cord-015369-72cjogxz 1404 53 ) ) -RRB- cord-015369-72cjogxz 1404 54 following follow VBG cord-015369-72cjogxz 1404 55 intrauterine intrauterine JJ cord-015369-72cjogxz 1404 56 death death NN cord-015369-72cjogxz 1404 57 or or CC cord-015369-72cjogxz 1404 58 legal legal JJ cord-015369-72cjogxz 1404 59 interruption interruption NN cord-015369-72cjogxz 1404 60 of of IN cord-015369-72cjogxz 1404 61 pregnancy pregnancy NN cord-015369-72cjogxz 1404 62 . . . cord-015369-72cjogxz 1405 1 Myelinated myelinated JJ cord-015369-72cjogxz 1405 2 sensory sensory JJ cord-015369-72cjogxz 1405 3 fibers fiber NNS cord-015369-72cjogxz 1405 4 were be VBD cord-015369-72cjogxz 1405 5 labeled label VBN cord-015369-72cjogxz 1405 6 with with IN cord-015369-72cjogxz 1405 7 an an DT cord-015369-72cjogxz 1405 8 antibody antibody NN cord-015369-72cjogxz 1405 9 raised raise VBN cord-015369-72cjogxz 1405 10 against against IN cord-015369-72cjogxz 1405 11 neurofilament neurofilament NNP cord-015369-72cjogxz 1405 12 ( ( -LRB- cord-015369-72cjogxz 1405 13 NF NF NNP cord-015369-72cjogxz 1405 14 ) ) -RRB- cord-015369-72cjogxz 1405 15 and and CC cord-015369-72cjogxz 1405 16 post post JJ cord-015369-72cjogxz 1405 17 - - JJ cord-015369-72cjogxz 1405 18 ganglionic ganglionic JJ cord-015369-72cjogxz 1405 19 sympathetic sympathetic JJ cord-015369-72cjogxz 1405 20 fibers fiber NNS cord-015369-72cjogxz 1405 21 were be VBD cord-015369-72cjogxz 1405 22 labeled label VBN cord-015369-72cjogxz 1405 23 with with IN cord-015369-72cjogxz 1405 24 an an DT cord-015369-72cjogxz 1405 25 antibody antibody NN cord-015369-72cjogxz 1405 26 raised raise VBN cord-015369-72cjogxz 1405 27 against against IN cord-015369-72cjogxz 1405 28 tyrosine tyrosine NN cord-015369-72cjogxz 1405 29 hydroxylase hydroxylase NN cord-015369-72cjogxz 1405 30 ( ( -LRB- cord-015369-72cjogxz 1405 31 TH TH NNP cord-015369-72cjogxz 1405 32 ) ) -RRB- cord-015369-72cjogxz 1405 33 . . . cord-015369-72cjogxz 1406 1 Choline Choline NNP cord-015369-72cjogxz 1406 2 acetylase acetylase NNP cord-015369-72cjogxz 1406 3 ( ( -LRB- cord-015369-72cjogxz 1406 4 ChAT ChAT NNP cord-015369-72cjogxz 1406 5 ) ) -RRB- cord-015369-72cjogxz 1406 6 at at IN cord-015369-72cjogxz 1406 7 cholinergic cholinergic JJ cord-015369-72cjogxz 1406 8 synapses synapsis NNS cord-015369-72cjogxz 1406 9 was be VBD cord-015369-72cjogxz 1406 10 labeled label VBN cord-015369-72cjogxz 1406 11 with with IN cord-015369-72cjogxz 1406 12 a a DT cord-015369-72cjogxz 1406 13 conventional conventional JJ cord-015369-72cjogxz 1406 14 antibody antibody NN cord-015369-72cjogxz 1406 15 . . . cord-015369-72cjogxz 1407 1 NF NF NNP cord-015369-72cjogxz 1407 2 . . . cord-015369-72cjogxz 1408 1 TH TH NNP cord-015369-72cjogxz 1408 2 , , , cord-015369-72cjogxz 1408 3 and and CC cord-015369-72cjogxz 1408 4 ChAT ChAT NNP cord-015369-72cjogxz 1408 5 immunoreactive immunoreactive JJ cord-015369-72cjogxz 1408 6 fibers fiber NNS cord-015369-72cjogxz 1408 7 were be VBD cord-015369-72cjogxz 1408 8 present present JJ cord-015369-72cjogxz 1408 9 in in IN cord-015369-72cjogxz 1408 10 parenchyma parenchyma NN cord-015369-72cjogxz 1408 11 of of IN cord-015369-72cjogxz 1408 12 the the DT cord-015369-72cjogxz 1408 13 head head NN cord-015369-72cjogxz 1408 14 , , , cord-015369-72cjogxz 1408 15 body body NN cord-015369-72cjogxz 1408 16 and and CC cord-015369-72cjogxz 1408 17 tail tail NN cord-015369-72cjogxz 1408 18 of of IN cord-015369-72cjogxz 1408 19 the the DT cord-015369-72cjogxz 1408 20 pancreas pancrea NNS cord-015369-72cjogxz 1408 21 at at IN cord-015369-72cjogxz 1408 22 variable variable JJ cord-015369-72cjogxz 1408 23 density density NN cord-015369-72cjogxz 1408 24 , , , cord-015369-72cjogxz 1408 25 but but CC cord-015369-72cjogxz 1408 26 the the DT cord-015369-72cjogxz 1408 27 relative relative JJ cord-015369-72cjogxz 1408 28 density density NN cord-015369-72cjogxz 1408 29 of of IN cord-015369-72cjogxz 1408 30 both both DT cord-015369-72cjogxz 1408 31 NF NF NNP cord-015369-72cjogxz 1408 32 and and CC cord-015369-72cjogxz 1408 33 ChAT ChAT NNP cord-015369-72cjogxz 1408 34 expressing express VBG cord-015369-72cjogxz 1408 35 fibers fiber NNS cord-015369-72cjogxz 1408 36 seemed seem VBD cord-015369-72cjogxz 1408 37 to to TO cord-015369-72cjogxz 1408 38 be be VB cord-015369-72cjogxz 1408 39 increasing increase VBG cord-015369-72cjogxz 1408 40 head head NN cord-015369-72cjogxz 1408 41 > > XX cord-015369-72cjogxz 1408 42 body body NN cord-015369-72cjogxz 1408 43 > > XX cord-015369-72cjogxz 1408 44 tail tail NN cord-015369-72cjogxz 1408 45 , , , cord-015369-72cjogxz 1408 46 whereas whereas IN cord-015369-72cjogxz 1408 47 for for IN cord-015369-72cjogxz 1408 48 TH TH NNP cord-015369-72cjogxz 1408 49 , , , cord-015369-72cjogxz 1408 50 a a DT cord-015369-72cjogxz 1408 51 relatively relatively RB cord-015369-72cjogxz 1408 52 even even JJ cord-015369-72cjogxz 1408 53 distribution distribution NN cord-015369-72cjogxz 1408 54 was be VBD cord-015369-72cjogxz 1408 55 observed observe VBN cord-015369-72cjogxz 1408 56 . . . cord-015369-72cjogxz 1409 1 In in IN cord-015369-72cjogxz 1409 2 addition addition NN cord-015369-72cjogxz 1409 3 to to IN cord-015369-72cjogxz 1409 4 this this DT cord-015369-72cjogxz 1409 5 set set NN cord-015369-72cjogxz 1409 6 of of IN cord-015369-72cjogxz 1409 7 sensory sensory JJ cord-015369-72cjogxz 1409 8 and and CC cord-015369-72cjogxz 1409 9 sympathetic sympathetic JJ cord-015369-72cjogxz 1409 10 nerve nerve NN cord-015369-72cjogxz 1409 11 fibers fiber NNS cord-015369-72cjogxz 1409 12 that that WDT cord-015369-72cjogxz 1409 13 terminate terminate VBP cord-015369-72cjogxz 1409 14 in in IN cord-015369-72cjogxz 1409 15 the the DT cord-015369-72cjogxz 1409 16 pancreas pancreas NN cord-015369-72cjogxz 1409 17 , , , cord-015369-72cjogxz 1409 18 there there EX cord-015369-72cjogxz 1409 19 were be VBD cord-015369-72cjogxz 1409 20 large large JJ cord-015369-72cjogxz 1409 21 bundles bundle NNS cord-015369-72cjogxz 1409 22 of of IN cord-015369-72cjogxz 1409 23 en en FW cord-015369-72cjogxz 1409 24 passant passant FW cord-015369-72cjogxz 1409 25 nerve nerve NN cord-015369-72cjogxz 1409 26 fibers fiber NNS cord-015369-72cjogxz 1409 27 in in IN cord-015369-72cjogxz 1409 28 the the DT cord-015369-72cjogxz 1409 29 dorsal dorsal JJ cord-015369-72cjogxz 1409 30 region region NN cord-015369-72cjogxz 1409 31 of of IN cord-015369-72cjogxz 1409 32 the the DT cord-015369-72cjogxz 1409 33 pancreas pancrea NNS cord-015369-72cjogxz 1409 34 that that WDT cord-015369-72cjogxz 1409 35 were be VBD cord-015369-72cjogxz 1409 36 associated associate VBN cord-015369-72cjogxz 1409 37 with with IN cord-015369-72cjogxz 1409 38 the the DT cord-015369-72cjogxz 1409 39 superior superior JJ cord-015369-72cjogxz 1409 40 mesenteric mesenteric JJ cord-015369-72cjogxz 1409 41 plexus plexus NN cord-015369-72cjogxz 1409 42 . . . cord-015369-72cjogxz 1410 1 These these DT cord-015369-72cjogxz 1410 2 data datum NNS cord-015369-72cjogxz 1410 3 suggest suggest VBP cord-015369-72cjogxz 1410 4 that that IN cord-015369-72cjogxz 1410 5 the the DT cord-015369-72cjogxz 1410 6 pancreas pancreas NN cord-015369-72cjogxz 1410 7 receives receive VBZ cord-015369-72cjogxz 1410 8 a a DT cord-015369-72cjogxz 1410 9 significant significant JJ cord-015369-72cjogxz 1410 10 sensory sensory JJ cord-015369-72cjogxz 1410 11 and and CC cord-015369-72cjogxz 1410 12 sympathetic sympathetic JJ cord-015369-72cjogxz 1410 13 innervation innervation NN cord-015369-72cjogxz 1410 14 during during IN cord-015369-72cjogxz 1410 15 fetal fetal JJ cord-015369-72cjogxz 1410 16 life life NN cord-015369-72cjogxz 1410 17 . . . cord-015369-72cjogxz 1411 1 Understanding understand VBG cord-015369-72cjogxz 1411 2 the the DT cord-015369-72cjogxz 1411 3 factors factor NNS cord-015369-72cjogxz 1411 4 and and CC cord-015369-72cjogxz 1411 5 disease disease NN cord-015369-72cjogxz 1411 6 states state NNS cord-015369-72cjogxz 1411 7 that that WDT cord-015369-72cjogxz 1411 8 may may MD cord-015369-72cjogxz 1411 9 alter alter VB cord-015369-72cjogxz 1411 10 the the DT cord-015369-72cjogxz 1411 11 distribution distribution NN cord-015369-72cjogxz 1411 12 of of IN cord-015369-72cjogxz 1411 13 nerve nerve NN cord-015369-72cjogxz 1411 14 structures structure NNS cord-015369-72cjogxz 1411 15 can can MD cord-015369-72cjogxz 1411 16 be be VB cord-015369-72cjogxz 1411 17 of of IN cord-015369-72cjogxz 1411 18 significance significance NN cord-015369-72cjogxz 1411 19 for for IN cord-015369-72cjogxz 1411 20 the the DT cord-015369-72cjogxz 1411 21 development development NN cord-015369-72cjogxz 1411 22 of of IN cord-015369-72cjogxz 1411 23 therapies therapy NNS cord-015369-72cjogxz 1411 24 in in IN cord-015369-72cjogxz 1411 25 pancreatic pancreatic JJ cord-015369-72cjogxz 1411 26 disorders disorder NNS cord-015369-72cjogxz 1411 27 of of IN cord-015369-72cjogxz 1411 28 child child NN cord-015369-72cjogxz 1411 29 and and CC cord-015369-72cjogxz 1411 30 adulthood adulthood NN cord-015369-72cjogxz 1411 31 . . . cord-015369-72cjogxz 1412 1 Background background NN cord-015369-72cjogxz 1412 2 . . . cord-015369-72cjogxz 1413 1 Electrospinning electrospinning NN cord-015369-72cjogxz 1413 2 of of IN cord-015369-72cjogxz 1413 3 polymers polymer NNS cord-015369-72cjogxz 1413 4 offers offer VBZ cord-015369-72cjogxz 1413 5 an an DT cord-015369-72cjogxz 1413 6 interesting interesting JJ cord-015369-72cjogxz 1413 7 approach approach NN cord-015369-72cjogxz 1413 8 to to TO cord-015369-72cjogxz 1413 9 fabricate fabricate VB cord-015369-72cjogxz 1413 10 nanostructured nanostructure VBN cord-015369-72cjogxz 1413 11 vascular vascular JJ cord-015369-72cjogxz 1413 12 substitutes substitute NNS cord-015369-72cjogxz 1413 13 which which WDT cord-015369-72cjogxz 1413 14 match match VBP cord-015369-72cjogxz 1413 15 the the DT cord-015369-72cjogxz 1413 16 biomechanical biomechanical JJ cord-015369-72cjogxz 1413 17 and and CC cord-015369-72cjogxz 1413 18 structural structural JJ cord-015369-72cjogxz 1413 19 properties property NNS cord-015369-72cjogxz 1413 20 of of IN cord-015369-72cjogxz 1413 21 native native JJ cord-015369-72cjogxz 1413 22 vessels vessel NNS cord-015369-72cjogxz 1413 23 . . . cord-015369-72cjogxz 1414 1 In in IN cord-015369-72cjogxz 1414 2 this this DT cord-015369-72cjogxz 1414 3 study study NN cord-015369-72cjogxz 1414 4 we -PRON- PRP cord-015369-72cjogxz 1414 5 investigated investigate VBD cord-015369-72cjogxz 1414 6 the the DT cord-015369-72cjogxz 1414 7 in in IN cord-015369-72cjogxz 1414 8 - - HYPH cord-015369-72cjogxz 1414 9 vivo vivo NN cord-015369-72cjogxz 1414 10 behaviour behaviour NN cord-015369-72cjogxz 1414 11 of of IN cord-015369-72cjogxz 1414 12 electrospun electrospun NNP cord-015369-72cjogxz 1414 13 , , , cord-015369-72cjogxz 1414 14 small small JJ cord-015369-72cjogxz 1414 15 diameter diameter NN cord-015369-72cjogxz 1414 16 conduits conduit NNS cord-015369-72cjogxz 1414 17 in in IN cord-015369-72cjogxz 1414 18 a a DT cord-015369-72cjogxz 1414 19 rat rat NN cord-015369-72cjogxz 1414 20 model model NN cord-015369-72cjogxz 1414 21 . . . cord-015369-72cjogxz 1415 1 Methods method NNS cord-015369-72cjogxz 1415 2 . . . cord-015369-72cjogxz 1416 1 Vascular vascular JJ cord-015369-72cjogxz 1416 2 grafts graft NNS cord-015369-72cjogxz 1416 3 with with IN cord-015369-72cjogxz 1416 4 an an DT cord-015369-72cjogxz 1416 5 inner inner JJ cord-015369-72cjogxz 1416 6 diameter diameter NN cord-015369-72cjogxz 1416 7 of of IN cord-015369-72cjogxz 1416 8 1.5 1.5 CD cord-015369-72cjogxz 1416 9 mm mm NNS cord-015369-72cjogxz 1416 10 were be VBD cord-015369-72cjogxz 1416 11 fabricated fabricate VBN cord-015369-72cjogxz 1416 12 by by IN cord-015369-72cjogxz 1416 13 electrospinning electrospinne VBG cord-015369-72cjogxz 1416 14 polyether polyether JJ cord-015369-72cjogxz 1416 15 - - HYPH cord-015369-72cjogxz 1416 16 urethane urethane NN cord-015369-72cjogxz 1416 17 . . . cord-015369-72cjogxz 1417 1 Prostheses prosthesis NNS cord-015369-72cjogxz 1417 2 were be VBD cord-015369-72cjogxz 1417 3 implanted implant VBN cord-015369-72cjogxz 1417 4 into into IN cord-015369-72cjogxz 1417 5 the the DT cord-015369-72cjogxz 1417 6 abdominal abdominal JJ cord-015369-72cjogxz 1417 7 aorta aorta NN cord-015369-72cjogxz 1417 8 of of IN cord-015369-72cjogxz 1417 9 40 40 CD cord-015369-72cjogxz 1417 10 rats rat NNS cord-015369-72cjogxz 1417 11 for for IN cord-015369-72cjogxz 1417 12 either either DT cord-015369-72cjogxz 1417 13 7 7 CD cord-015369-72cjogxz 1417 14 days day NNS cord-015369-72cjogxz 1417 15 , , , cord-015369-72cjogxz 1417 16 4 4 CD cord-015369-72cjogxz 1417 17 weeks week NNS cord-015369-72cjogxz 1417 18 , , , cord-015369-72cjogxz 1417 19 3 3 CD cord-015369-72cjogxz 1417 20 or or CC cord-015369-72cjogxz 1417 21 6 6 CD cord-015369-72cjogxz 1417 22 months month NNS cord-015369-72cjogxz 1417 23 . . . cord-015369-72cjogxz 1418 1 Retrieved retrieve VBN cord-015369-72cjogxz 1418 2 specimens specimen NNS cord-015369-72cjogxz 1418 3 were be VBD cord-015369-72cjogxz 1418 4 evaluated evaluate VBN cord-015369-72cjogxz 1418 5 by by IN cord-015369-72cjogxz 1418 6 conventional conventional JJ cord-015369-72cjogxz 1418 7 histology histology NN cord-015369-72cjogxz 1418 8 , , , cord-015369-72cjogxz 1418 9 immunohistochemistry immunohistochemistry NN cord-015369-72cjogxz 1418 10 and and CC cord-015369-72cjogxz 1418 11 scanning scan VBG cord-015369-72cjogxz 1418 12 electron electron NN cord-015369-72cjogxz 1418 13 microscopy microscopy NN cord-015369-72cjogxz 1418 14 . . . cord-015369-72cjogxz 1419 1 Results result NNS cord-015369-72cjogxz 1419 2 . . . cord-015369-72cjogxz 1420 1 The the DT cord-015369-72cjogxz 1420 2 overall overall JJ cord-015369-72cjogxz 1420 3 patency patency NN cord-015369-72cjogxz 1420 4 rate rate NN cord-015369-72cjogxz 1420 5 of of IN cord-015369-72cjogxz 1420 6 the the DT cord-015369-72cjogxz 1420 7 electrospun electrospun NNP cord-015369-72cjogxz 1420 8 conduits conduit NNS cord-015369-72cjogxz 1420 9 was be VBD cord-015369-72cjogxz 1420 10 95 95 CD cord-015369-72cjogxz 1420 11 % % NN cord-015369-72cjogxz 1420 12 ; ; , cord-015369-72cjogxz 1420 13 neither neither CC cord-015369-72cjogxz 1420 14 foreign foreign JJ cord-015369-72cjogxz 1420 15 body body NN cord-015369-72cjogxz 1420 16 - - HYPH cord-015369-72cjogxz 1420 17 type type NN cord-015369-72cjogxz 1420 18 reactions reaction NNS cord-015369-72cjogxz 1420 19 nor nor CC cord-015369-72cjogxz 1420 20 gross gross JJ cord-015369-72cjogxz 1420 21 evidence evidence NN cord-015369-72cjogxz 1420 22 of of IN cord-015369-72cjogxz 1420 23 degradation degradation NN cord-015369-72cjogxz 1420 24 were be VBD cord-015369-72cjogxz 1420 25 observed observe VBN cord-015369-72cjogxz 1420 26 . . . cord-015369-72cjogxz 1421 1 Within within IN cord-015369-72cjogxz 1421 2 1 1 CD cord-015369-72cjogxz 1421 3 month month NN cord-015369-72cjogxz 1421 4 after after IN cord-015369-72cjogxz 1421 5 implantation implantation NN cord-015369-72cjogxz 1421 6 , , , cord-015369-72cjogxz 1421 7 midgraft midgraft NN cord-015369-72cjogxz 1421 8 regions region NNS cord-015369-72cjogxz 1421 9 were be VBD cord-015369-72cjogxz 1421 10 completely completely RB cord-015369-72cjogxz 1421 11 covered cover VBN cord-015369-72cjogxz 1421 12 with with IN cord-015369-72cjogxz 1421 13 endothelial endothelial JJ cord-015369-72cjogxz 1421 14 cells cell NNS cord-015369-72cjogxz 1421 15 . . . cord-015369-72cjogxz 1422 1 Immunohistochemistry Immunohistochemistry NNP cord-015369-72cjogxz 1422 2 revealed reveal VBD cord-015369-72cjogxz 1422 3 a a DT cord-015369-72cjogxz 1422 4 significant significant JJ cord-015369-72cjogxz 1422 5 immigration immigration NN cord-015369-72cjogxz 1422 6 of of IN cord-015369-72cjogxz 1422 7 CD CD NNP cord-015369-72cjogxz 1422 8 34þ 34þ NNS cord-015369-72cjogxz 1422 9 cells cell NNS cord-015369-72cjogxz 1422 10 from from IN cord-015369-72cjogxz 1422 11 the the DT cord-015369-72cjogxz 1422 12 luminal luminal JJ cord-015369-72cjogxz 1422 13 side side NN cord-015369-72cjogxz 1422 14 of of IN cord-015369-72cjogxz 1422 15 the the DT cord-015369-72cjogxz 1422 16 graft graft NN cord-015369-72cjogxz 1422 17 into into IN cord-015369-72cjogxz 1422 18 the the DT cord-015369-72cjogxz 1422 19 prosthesis prosthesis NN cord-015369-72cjogxz 1422 20 wall wall NN cord-015369-72cjogxz 1422 21 . . . cord-015369-72cjogxz 1423 1 Within within IN cord-015369-72cjogxz 1423 2 6 6 CD cord-015369-72cjogxz 1423 3 months month NNS cord-015369-72cjogxz 1423 4 , , , cord-015369-72cjogxz 1423 5 vascular vascular JJ cord-015369-72cjogxz 1423 6 specific specific JJ cord-015369-72cjogxz 1423 7 smooth smooth JJ cord-015369-72cjogxz 1423 8 muscle muscle NN cord-015369-72cjogxz 1423 9 cells cell NNS cord-015369-72cjogxz 1423 10 ( ( -LRB- cord-015369-72cjogxz 1423 11 actin actin NNP cord-015369-72cjogxz 1423 12 þ þ NNP cord-015369-72cjogxz 1423 13 , , , cord-015369-72cjogxz 1423 14 desmin desmin NNP cord-015369-72cjogxz 1423 15 þ þ NNP cord-015369-72cjogxz 1423 16 ) ) -RRB- cord-015369-72cjogxz 1423 17 repopulated repopulate VBD cord-015369-72cjogxz 1423 18 half half NN cord-015369-72cjogxz 1423 19 of of IN cord-015369-72cjogxz 1423 20 the the DT cord-015369-72cjogxz 1423 21 conduit conduit NN cord-015369-72cjogxz 1423 22 wall wall NN cord-015369-72cjogxz 1423 23 . . . cord-015369-72cjogxz 1424 1 Conclusions conclusion NNS cord-015369-72cjogxz 1424 2 . . . cord-015369-72cjogxz 1425 1 Nanostructured Nanostructured NNP cord-015369-72cjogxz 1425 2 electrospun electrospun NNP cord-015369-72cjogxz 1425 3 polyurethane polyurethane NN cord-015369-72cjogxz 1425 4 conduits conduit NNS cord-015369-72cjogxz 1425 5 offer offer VBP cord-015369-72cjogxz 1425 6 biomechanics biomechanic NNS cord-015369-72cjogxz 1425 7 and and CC cord-015369-72cjogxz 1425 8 bioinertness bioinertness NN cord-015369-72cjogxz 1425 9 comparable comparable JJ cord-015369-72cjogxz 1425 10 to to IN cord-015369-72cjogxz 1425 11 native native JJ cord-015369-72cjogxz 1425 12 vessels vessel NNS cord-015369-72cjogxz 1425 13 and and CC cord-015369-72cjogxz 1425 14 promote promote VB cord-015369-72cjogxz 1425 15 the the DT cord-015369-72cjogxz 1425 16 immigration immigration NN cord-015369-72cjogxz 1425 17 and and CC cord-015369-72cjogxz 1425 18 differentation differentation NN cord-015369-72cjogxz 1425 19 of of IN cord-015369-72cjogxz 1425 20 vascular vascular JJ cord-015369-72cjogxz 1425 21 specific specific JJ cord-015369-72cjogxz 1425 22 cells cell NNS cord-015369-72cjogxz 1425 23 in in IN cord-015369-72cjogxz 1425 24 - - HYPH cord-015369-72cjogxz 1425 25 vivo vivo NN cord-015369-72cjogxz 1425 26 . . . cord-015369-72cjogxz 1426 1 Diskussion Diskussion NNP cord-015369-72cjogxz 1426 2 . . . cord-015369-72cjogxz 1427 1 Die die VB cord-015369-72cjogxz 1427 2 coloskopische coloskopische NNP cord-015369-72cjogxz 1427 3 Mukosektomie Mukosektomie NNP cord-015369-72cjogxz 1427 4 hat hat NN cord-015369-72cjogxz 1427 5 den den NN cord-015369-72cjogxz 1427 6 Nachteil Nachteil NNP cord-015369-72cjogxz 1427 7 des des FW cord-015369-72cjogxz 1427 8 meist meist NNP cord-015369-72cjogxz 1427 9 fragmentierten fragmentierten NNP cord-015369-72cjogxz 1427 10 Präparates Präparates NNP cord-015369-72cjogxz 1427 11 , , , cord-015369-72cjogxz 1427 12 Gefahr Gefahr NNP cord-015369-72cjogxz 1427 13 des des NNP cord-015369-72cjogxz 1427 14 Hinterlassens Hinterlassens NNP cord-015369-72cjogxz 1427 15 von von NNP cord-015369-72cjogxz 1427 16 kleinen kleinen NNP cord-015369-72cjogxz 1427 17 Adenomresten Adenomresten NNP cord-015369-72cjogxz 1427 18 , , , cord-015369-72cjogxz 1427 19 Implementierung Implementierung NNP cord-015369-72cjogxz 1427 20 mehrfacher mehrfacher RBR cord-015369-72cjogxz 1427 21 Sitzungen Sitzungen NNP cord-015369-72cjogxz 1427 22 und und XX cord-015369-72cjogxz 1427 23 der der NNP cord-015369-72cjogxz 1427 24 Narbenstenose Narbenstenose NNP cord-015369-72cjogxz 1427 25 durch durch NNP cord-015369-72cjogxz 1427 26 die die VBP cord-015369-72cjogxz 1427 27 fehlende fehlende FW cord-015369-72cjogxz 1427 28 Naht Naht NNP cord-015369-72cjogxz 1427 29 . . . cord-015369-72cjogxz 1428 1 Die die VB cord-015369-72cjogxz 1428 2 TEM tem NN cord-015369-72cjogxz 1428 3 ermöglicht ermöglicht NNP cord-015369-72cjogxz 1428 4 i i PRP cord-015369-72cjogxz 1429 1 m m LS cord-015369-72cjogxz 1429 2 Gegensatz Gegensatz NNP cord-015369-72cjogxz 1429 3 zur zur NNP cord-015369-72cjogxz 1429 4 coloskopischen coloskopischen NNP cord-015369-72cjogxz 1430 1 Mukosektomie Mukosektomie NNP cord-015369-72cjogxz 1430 2 die die VBP cord-015369-72cjogxz 1430 3 zusätzliche zusätzliche NNP cord-015369-72cjogxz 1430 4 Resektion Resektion NNP cord-015369-72cjogxz 1430 5 von von NNP cord-015369-72cjogxz 1430 6 Submukosa Submukosa NNP cord-015369-72cjogxz 1431 1 und und IN cord-015369-72cjogxz 1431 2 Muskularis Muskularis NNP cord-015369-72cjogxz 1431 3 und und IN cord-015369-72cjogxz 1431 4 somit somit NN cord-015369-72cjogxz 1432 1 eine eine NNP cord-015369-72cjogxz 1432 2 Entfernung Entfernung NNP cord-015369-72cjogxz 1432 3 des des NNP cord-015369-72cjogxz 1432 4 Adenomrezidivs Adenomrezidivs NNP cord-015369-72cjogxz 1432 5 in in IN cord-015369-72cjogxz 1432 6 toto toto NNP cord-015369-72cjogxz 1432 7 mit mit NNP cord-015369-72cjogxz 1432 8 primärer primärer NNP cord-015369-72cjogxz 1432 9 Naht Naht NNP cord-015369-72cjogxz 1432 10 . . . cord-015369-72cjogxz 1433 1 Die die VB cord-015369-72cjogxz 1433 2 transanale transanale NNP cord-015369-72cjogxz 1434 1 Excision excision NN cord-015369-72cjogxz 1434 2 nach nach NNP cord-015369-72cjogxz 1434 3 Parks Parks NNP cord-015369-72cjogxz 1434 4 hat hat VBP cord-015369-72cjogxz 1434 5 eine eine NNP cord-015369-72cjogxz 1434 6 5 5 CD cord-015369-72cjogxz 1434 7 - - SYM cord-015369-72cjogxz 1434 8 10 10 CD cord-015369-72cjogxz 1434 9 fach fach NN cord-015369-72cjogxz 1434 10 höhere höhere NN cord-015369-72cjogxz 1434 11 Rezidivrate Rezidivrate NNP cord-015369-72cjogxz 1434 12 als als NNP cord-015369-72cjogxz 1434 13 die die VBP cord-015369-72cjogxz 1434 14 TEM tem NN cord-015369-72cjogxz 1434 15 , , , cord-015369-72cjogxz 1434 16 weshalb weshalb NNP cord-015369-72cjogxz 1434 17 der der NN cord-015369-72cjogxz 1434 18 TEM TEM NNP cord-015369-72cjogxz 1434 19 unbedingt unbedingt NN cord-015369-72cjogxz 1434 20 der der NNP cord-015369-72cjogxz 1434 21 Vorzug Vorzug NNP cord-015369-72cjogxz 1434 22 zu zu NNP cord-015369-72cjogxz 1434 23 geben geben NNP cord-015369-72cjogxz 1434 24 ist ist NNP cord-015369-72cjogxz 1434 25 . . . cord-015369-72cjogxz 1435 1 Mit Mit NNP cord-015369-72cjogxz 1435 2 der der NNP cord-015369-72cjogxz 1435 3 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 1435 4 vorderen vorderen NNP cord-015369-72cjogxz 1435 5 Resektion Resektion NNP cord-015369-72cjogxz 1435 6 kann kann NNP cord-015369-72cjogxz 1435 7 wie wie NNP cord-015369-72cjogxz 1435 8 mit mit NNP cord-015369-72cjogxz 1435 9 der der NN cord-015369-72cjogxz 1435 10 TEM TEM NNP cord-015369-72cjogxz 1435 11 das das NNP cord-015369-72cjogxz 1435 12 Adenomrezidiv Adenomrezidiv NNP cord-015369-72cjogxz 1435 13 sicher sicher NNP cord-015369-72cjogxz 1435 14 komplett komplett NNP cord-015369-72cjogxz 1435 15 entfernt entfernt NNP cord-015369-72cjogxz 1435 16 werden werden NNP cord-015369-72cjogxz 1435 17 , , , cord-015369-72cjogxz 1436 1 sie sie NNP cord-015369-72cjogxz 1436 2 hat hat NN cord-015369-72cjogxz 1436 3 aber aber NNP cord-015369-72cjogxz 1436 4 den den NNP cord-015369-72cjogxz 1436 5 Nachteil Nachteil NNP cord-015369-72cjogxz 1436 6 der der NNP cord-015369-72cjogxz 1436 7 höheren höheren NNP cord-015369-72cjogxz 1437 1 Morbidität Morbidität NNP cord-015369-72cjogxz 1437 2 , , , cord-015369-72cjogxz 1437 3 Letalität Letalität NNP cord-015369-72cjogxz 1437 4 und und VBD cord-015369-72cjogxz 1437 5 der der NNP cord-015369-72cjogxz 1437 6 schlechteren schlechteren NNP cord-015369-72cjogxz 1437 7 funktionellen funktionellen NNP cord-015369-72cjogxz 1437 8 Spätergebnisse Spätergebnisse NNP cord-015369-72cjogxz 1437 9 . . . cord-015369-72cjogxz 1438 1 I -PRON- PRP cord-015369-72cjogxz 1438 2 m be VBP cord-015369-72cjogxz 1438 3 eigenen eigenen NNP cord-015369-72cjogxz 1438 4 Krankengut Krankengut NNP cord-015369-72cjogxz 1438 5 hat hat NN cord-015369-72cjogxz 1438 6 sich sich XX cord-015369-72cjogxz 1438 7 die die VB cord-015369-72cjogxz 1439 1 TEM tem NN cord-015369-72cjogxz 1439 2 als als NN cord-015369-72cjogxz 1439 3 optimales optimale NNS cord-015369-72cjogxz 1439 4 Therapieverfahren Therapieverfahren NNP cord-015369-72cjogxz 1439 5 zur zur NNP cord-015369-72cjogxz 1439 6 Behandlung Behandlung NNP cord-015369-72cjogxz 1439 7 von von NNP cord-015369-72cjogxz 1439 8 Rektumadenomrezidiven Rektumadenomrezidiven NNP cord-015369-72cjogxz 1439 9 bewährt bewährt NNP cord-015369-72cjogxz 1439 10 . . . cord-015369-72cjogxz 1440 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1440 2 . . . cord-015369-72cjogxz 1441 1 Die die VB cord-015369-72cjogxz 1441 2 TEM tem NN cord-015369-72cjogxz 1441 3 ist ist NN cord-015369-72cjogxz 1441 4 bei bei NN cord-015369-72cjogxz 1441 5 der der NNP cord-015369-72cjogxz 1441 6 Behandlung Behandlung NNP cord-015369-72cjogxz 1441 7 des des NNP cord-015369-72cjogxz 1441 8 Rektumadenomrezidivs Rektumadenomrezidivs NNP cord-015369-72cjogxz 1441 9 alternativen alternativen NNP cord-015369-72cjogxz 1441 10 Therapieverfahren Therapieverfahren NNP cord-015369-72cjogxz 1441 11 ü ü NN cord-015369-72cjogxz 1441 12 berlegen berlegen NNP cord-015369-72cjogxz 1441 13 . . . cord-015369-72cjogxz 1442 1 The the DT cord-015369-72cjogxz 1442 2 impact impact NN cord-015369-72cjogxz 1442 3 of of IN cord-015369-72cjogxz 1442 4 computed compute VBN cord-015369-72cjogxz 1442 5 tomography tomography NN cord-015369-72cjogxz 1442 6 in in IN cord-015369-72cjogxz 1442 7 acute acute JJ cord-015369-72cjogxz 1442 8 appendicitis appendicitis NN cord-015369-72cjogxz 1442 9 and and CC cord-015369-72cjogxz 1442 10 obese obese JJ cord-015369-72cjogxz 1442 11 patients patient NNS cord-015369-72cjogxz 1443 1 M. M. NNP cord-015369-72cjogxz 1443 2 von von NNP cord-015369-72cjogxz 1443 3 der der NNP cord-015369-72cjogxz 1443 4 Groeben Groeben NNP cord-015369-72cjogxz 1443 5 , , , cord-015369-72cjogxz 1443 6 V. V. NNP cord-015369-72cjogxz 1443 7 Neuhaus Neuhaus NNP cord-015369-72cjogxz 1443 8 , , , cord-015369-72cjogxz 1443 9 O. O. NNP cord-015369-72cjogxz 1443 10 Schöb Schöb NNP cord-015369-72cjogxz 1443 11 Background Background NNP cord-015369-72cjogxz 1443 12 . . . cord-015369-72cjogxz 1444 1 Acute acute JJ cord-015369-72cjogxz 1444 2 appendicitis appendicitis NN cord-015369-72cjogxz 1444 3 is be VBZ cord-015369-72cjogxz 1444 4 diagnose diagnose VBN cord-015369-72cjogxz 1444 5 by by IN cord-015369-72cjogxz 1444 6 clinical clinical JJ cord-015369-72cjogxz 1444 7 examination examination NN cord-015369-72cjogxz 1444 8 , , , cord-015369-72cjogxz 1444 9 ultrasound ultrasound NN cord-015369-72cjogxz 1444 10 and and CC cord-015369-72cjogxz 1444 11 laboratory laboratory NN cord-015369-72cjogxz 1444 12 tests test NNS cord-015369-72cjogxz 1444 13 . . . cord-015369-72cjogxz 1445 1 However however RB cord-015369-72cjogxz 1445 2 , , , cord-015369-72cjogxz 1445 3 ultrasonography ultrasonography NN cord-015369-72cjogxz 1445 4 may may MD cord-015369-72cjogxz 1445 5 not not RB cord-015369-72cjogxz 1445 6 be be VB cord-015369-72cjogxz 1445 7 sufficient sufficient JJ cord-015369-72cjogxz 1445 8 for for IN cord-015369-72cjogxz 1445 9 a a DT cord-015369-72cjogxz 1445 10 definite definite JJ cord-015369-72cjogxz 1445 11 diagnosis diagnosis NN cord-015369-72cjogxz 1445 12 in in IN cord-015369-72cjogxz 1445 13 obese obese JJ cord-015369-72cjogxz 1445 14 patients patient NNS cord-015369-72cjogxz 1445 15 and and CC cord-015369-72cjogxz 1445 16 in in IN cord-015369-72cjogxz 1445 17 the the DT cord-015369-72cjogxz 1445 18 case case NN cord-015369-72cjogxz 1445 19 of of IN cord-015369-72cjogxz 1445 20 meteorism meteorism NN cord-015369-72cjogxz 1445 21 . . . cord-015369-72cjogxz 1446 1 In in IN cord-015369-72cjogxz 1446 2 this this DT cord-015369-72cjogxz 1446 3 study study NN cord-015369-72cjogxz 1446 4 , , , cord-015369-72cjogxz 1446 5 the the DT cord-015369-72cjogxz 1446 6 clinical clinical JJ cord-015369-72cjogxz 1446 7 relevance relevance NN cord-015369-72cjogxz 1446 8 of of IN cord-015369-72cjogxz 1446 9 computed compute VBN cord-015369-72cjogxz 1446 10 tomography tomography NN cord-015369-72cjogxz 1446 11 to to TO cord-015369-72cjogxz 1446 12 diagnose diagnose VB cord-015369-72cjogxz 1446 13 acute acute JJ cord-015369-72cjogxz 1446 14 appendicitis appendicitis NN cord-015369-72cjogxz 1446 15 , , , cord-015369-72cjogxz 1446 16 especially especially RB cord-015369-72cjogxz 1446 17 in in IN cord-015369-72cjogxz 1446 18 obese obese JJ cord-015369-72cjogxz 1446 19 patients patient NNS cord-015369-72cjogxz 1446 20 , , , cord-015369-72cjogxz 1446 21 was be VBD cord-015369-72cjogxz 1446 22 evaluated evaluate VBN cord-015369-72cjogxz 1446 23 in in IN cord-015369-72cjogxz 1446 24 a a DT cord-015369-72cjogxz 1446 25 retrospective retrospective JJ cord-015369-72cjogxz 1446 26 study study NN cord-015369-72cjogxz 1446 27 . . . cord-015369-72cjogxz 1447 1 Methods method NNS cord-015369-72cjogxz 1447 2 . . . cord-015369-72cjogxz 1448 1 Patients patient NNS cord-015369-72cjogxz 1448 2 suffering suffer VBG cord-015369-72cjogxz 1448 3 from from IN cord-015369-72cjogxz 1448 4 acute acute JJ cord-015369-72cjogxz 1448 5 pain pain NN cord-015369-72cjogxz 1448 6 in in IN cord-015369-72cjogxz 1448 7 the the DT cord-015369-72cjogxz 1448 8 right right JJ cord-015369-72cjogxz 1448 9 underbelly underbelly NN cord-015369-72cjogxz 1448 10 were be VBD cord-015369-72cjogxz 1448 11 examined examine VBN cord-015369-72cjogxz 1448 12 for for IN cord-015369-72cjogxz 1448 13 appendicitis appendicitis NN cord-015369-72cjogxz 1448 14 by by IN cord-015369-72cjogxz 1448 15 means mean NNS cord-015369-72cjogxz 1448 16 of of IN cord-015369-72cjogxz 1448 17 clinical clinical JJ cord-015369-72cjogxz 1448 18 examination examination NN cord-015369-72cjogxz 1448 19 , , , cord-015369-72cjogxz 1448 20 ultrasound ultrasound NN cord-015369-72cjogxz 1448 21 imaging imaging NN cord-015369-72cjogxz 1448 22 and and CC cord-015369-72cjogxz 1448 23 laboratory laboratory NN cord-015369-72cjogxz 1448 24 tests test NNS cord-015369-72cjogxz 1448 25 . . . cord-015369-72cjogxz 1449 1 In in IN cord-015369-72cjogxz 1449 2 case case NN cord-015369-72cjogxz 1449 3 of of IN cord-015369-72cjogxz 1449 4 definite definite JJ cord-015369-72cjogxz 1449 5 diagnostic diagnostic JJ cord-015369-72cjogxz 1449 6 findings finding NNS cord-015369-72cjogxz 1449 7 ( ( -LRB- cord-015369-72cjogxz 1449 8 n n NN cord-015369-72cjogxz 1449 9 ¼ ¼ NNP cord-015369-72cjogxz 1449 10 160 160 CD cord-015369-72cjogxz 1449 11 ) ) -RRB- cord-015369-72cjogxz 1449 12 , , , cord-015369-72cjogxz 1449 13 appendectomy appendectomy NN cord-015369-72cjogxz 1449 14 was be VBD cord-015369-72cjogxz 1449 15 accomplished accomplish VBN cord-015369-72cjogxz 1449 16 by by IN cord-015369-72cjogxz 1449 17 laparoscopy laparoscopy NN cord-015369-72cjogxz 1449 18 . . . cord-015369-72cjogxz 1450 1 In in IN cord-015369-72cjogxz 1450 2 case case NN cord-015369-72cjogxz 1450 3 of of IN cord-015369-72cjogxz 1450 4 negative negative JJ cord-015369-72cjogxz 1450 5 ultrasonography ultrasonography NN cord-015369-72cjogxz 1450 6 findings finding NNS cord-015369-72cjogxz 1450 7 ( ( -LRB- cord-015369-72cjogxz 1450 8 n n CC cord-015369-72cjogxz 1450 9 ¼ ¼ NNP cord-015369-72cjogxz 1450 10 38 38 CD cord-015369-72cjogxz 1450 11 ) ) -RRB- cord-015369-72cjogxz 1450 12 , , , cord-015369-72cjogxz 1450 13 patients patient NNS cord-015369-72cjogxz 1450 14 were be VBD cord-015369-72cjogxz 1450 15 reexamined reexamine VBN cord-015369-72cjogxz 1450 16 by by IN cord-015369-72cjogxz 1450 17 CT CT NNP cord-015369-72cjogxz 1450 18 the the DT cord-015369-72cjogxz 1450 19 same same JJ cord-015369-72cjogxz 1450 20 day day NN cord-015369-72cjogxz 1450 21 ( ( -LRB- cord-015369-72cjogxz 1450 22 n n NN cord-015369-72cjogxz 1450 23 ¼ ¼ NNP cord-015369-72cjogxz 1450 24 20 20 CD cord-015369-72cjogxz 1450 25 ) ) -RRB- cord-015369-72cjogxz 1450 26 or or CC cord-015369-72cjogxz 1450 27 by by IN cord-015369-72cjogxz 1450 28 ultrasound ultrasound NN cord-015369-72cjogxz 1450 29 imaging imaging NN cord-015369-72cjogxz 1450 30 and and CC cord-015369-72cjogxz 1450 31 laboratory laboratory NN cord-015369-72cjogxz 1450 32 tests test NNS cord-015369-72cjogxz 1450 33 the the DT cord-015369-72cjogxz 1450 34 next next JJ cord-015369-72cjogxz 1450 35 day day NN cord-015369-72cjogxz 1450 36 after after IN cord-015369-72cjogxz 1450 37 admission admission NN cord-015369-72cjogxz 1450 38 ( ( -LRB- cord-015369-72cjogxz 1450 39 n n NNP cord-015369-72cjogxz 1450 40 ¼ ¼ NNP cord-015369-72cjogxz 1450 41 18 18 CD cord-015369-72cjogxz 1450 42 ) ) -RRB- cord-015369-72cjogxz 1450 43 . . . cord-015369-72cjogxz 1451 1 Results result NNS cord-015369-72cjogxz 1451 2 . . . cord-015369-72cjogxz 1452 1 Patients patient NNS cord-015369-72cjogxz 1452 2 with with IN cord-015369-72cjogxz 1452 3 negative negative JJ cord-015369-72cjogxz 1452 4 initial initial JJ cord-015369-72cjogxz 1452 5 ultrasonography ultrasonography NN cord-015369-72cjogxz 1452 6 findings finding NNS cord-015369-72cjogxz 1452 7 ( ( -LRB- cord-015369-72cjogxz 1452 8 n n CC cord-015369-72cjogxz 1452 9 ¼ ¼ NNP cord-015369-72cjogxz 1452 10 38 38 CD cord-015369-72cjogxz 1452 11 ) ) -RRB- cord-015369-72cjogxz 1452 12 , , , cord-015369-72cjogxz 1452 13 duration duration NN cord-015369-72cjogxz 1452 14 of of IN cord-015369-72cjogxz 1452 15 anamnesis anamnesis NN cord-015369-72cjogxz 1452 16 ranged range VBD cord-015369-72cjogxz 1452 17 from from IN cord-015369-72cjogxz 1452 18 12 12 CD cord-015369-72cjogxz 1452 19 to to IN cord-015369-72cjogxz 1452 20 120 120 CD cord-015369-72cjogxz 1452 21 h h NN cord-015369-72cjogxz 1452 22 and and CC cord-015369-72cjogxz 1452 23 14 14 CD cord-015369-72cjogxz 1452 24 ( ( -LRB- cord-015369-72cjogxz 1452 25 36.8 36.8 CD cord-015369-72cjogxz 1452 26 % % NN cord-015369-72cjogxz 1452 27 ) ) -RRB- cord-015369-72cjogxz 1452 28 of of IN cord-015369-72cjogxz 1452 29 these these DT cord-015369-72cjogxz 1452 30 patients patient NNS cord-015369-72cjogxz 1452 31 were be VBD cord-015369-72cjogxz 1452 32 considered consider VBN cord-015369-72cjogxz 1452 33 as as IN cord-015369-72cjogxz 1452 34 obese obese JJ cord-015369-72cjogxz 1452 35 due due IN cord-015369-72cjogxz 1452 36 to to IN cord-015369-72cjogxz 1452 37 their -PRON- PRP$ cord-015369-72cjogxz 1452 38 body body NN cord-015369-72cjogxz 1452 39 mass mass NN cord-015369-72cjogxz 1452 40 index index NN cord-015369-72cjogxz 1452 41 ( ( -LRB- cord-015369-72cjogxz 1452 42 BMI BMI NNP cord-015369-72cjogxz 1452 43 ! ! . cord-015369-72cjogxz 1452 44 30 30 CD cord-015369-72cjogxz 1452 45 kg kg NN cord-015369-72cjogxz 1452 46 / / SYM cord-015369-72cjogxz 1452 47 m m NN cord-015369-72cjogxz 1452 48 2 2 CD cord-015369-72cjogxz 1452 49 ) ) -RRB- cord-015369-72cjogxz 1452 50 . . . cord-015369-72cjogxz 1453 1 In in IN cord-015369-72cjogxz 1453 2 comparison comparison NN cord-015369-72cjogxz 1453 3 , , , cord-015369-72cjogxz 1453 4 only only RB cord-015369-72cjogxz 1453 5 7.3 7.3 CD cord-015369-72cjogxz 1453 6 % % NN cord-015369-72cjogxz 1453 7 of of IN cord-015369-72cjogxz 1453 8 the the DT cord-015369-72cjogxz 1453 9 patients patient NNS cord-015369-72cjogxz 1453 10 with with IN cord-015369-72cjogxz 1453 11 positive positive JJ cord-015369-72cjogxz 1453 12 ultrasonography ultrasonography NN cord-015369-72cjogxz 1453 13 findings finding NNS cord-015369-72cjogxz 1453 14 were be VBD cord-015369-72cjogxz 1453 15 obese obese JJ cord-015369-72cjogxz 1453 16 . . . cord-015369-72cjogxz 1454 1 Among among IN cord-015369-72cjogxz 1454 2 the the DT cord-015369-72cjogxz 1454 3 20 20 CD cord-015369-72cjogxz 1454 4 patients patient NNS cord-015369-72cjogxz 1454 5 further further RB cord-015369-72cjogxz 1454 6 examined examine VBN cord-015369-72cjogxz 1454 7 by by IN cord-015369-72cjogxz 1454 8 CT CT NNP cord-015369-72cjogxz 1454 9 , , , cord-015369-72cjogxz 1454 10 17 17 CD cord-015369-72cjogxz 1454 11 ( ( -LRB- cord-015369-72cjogxz 1454 12 85.0 85.0 CD cord-015369-72cjogxz 1454 13 % % NN cord-015369-72cjogxz 1454 14 ) ) -RRB- cord-015369-72cjogxz 1454 15 showed show VBD cord-015369-72cjogxz 1454 16 a a DT cord-015369-72cjogxz 1454 17 BMI bmi NN cord-015369-72cjogxz 1454 18 ! ! . cord-015369-72cjogxz 1455 1 30 30 CD cord-015369-72cjogxz 1455 2 kg kg NN cord-015369-72cjogxz 1455 3 / / SYM cord-015369-72cjogxz 1455 4 m m NN cord-015369-72cjogxz 1455 5 2 2 CD cord-015369-72cjogxz 1455 6 . . . cord-015369-72cjogxz 1456 1 Duration duration NN cord-015369-72cjogxz 1456 2 of of IN cord-015369-72cjogxz 1456 3 anamnesis anamnesis NN cord-015369-72cjogxz 1456 4 ranged range VBD cord-015369-72cjogxz 1456 5 from from IN cord-015369-72cjogxz 1456 6 12 12 CD cord-015369-72cjogxz 1456 7 to to TO cord-015369-72cjogxz 1456 8 48 48 CD cord-015369-72cjogxz 1456 9 h. h. NN cord-015369-72cjogxz 1457 1 In in IN cord-015369-72cjogxz 1457 2 contrast contrast NN cord-015369-72cjogxz 1457 3 , , , cord-015369-72cjogxz 1457 4 among among IN cord-015369-72cjogxz 1457 5 the the DT cord-015369-72cjogxz 1457 6 18 18 CD cord-015369-72cjogxz 1457 7 patients patient NNS cord-015369-72cjogxz 1457 8 reexamined reexamine VBN cord-015369-72cjogxz 1457 9 by by IN cord-015369-72cjogxz 1457 10 ultrasound ultrasound NN cord-015369-72cjogxz 1457 11 imaging imaging NN cord-015369-72cjogxz 1457 12 , , , cord-015369-72cjogxz 1457 13 only only RB cord-015369-72cjogxz 1457 14 two two CD cord-015369-72cjogxz 1457 15 showed show VBD cord-015369-72cjogxz 1457 16 a a DT cord-015369-72cjogxz 1457 17 BMI bmi NN cord-015369-72cjogxz 1457 18 ! ! . cord-015369-72cjogxz 1458 1 30 30 CD cord-015369-72cjogxz 1458 2 kg kg NN cord-015369-72cjogxz 1458 3 / / SYM cord-015369-72cjogxz 1458 4 m m NN cord-015369-72cjogxz 1458 5 2 2 CD cord-015369-72cjogxz 1458 6 . . . cord-015369-72cjogxz 1459 1 Conclusions conclusion NNS cord-015369-72cjogxz 1459 2 . . . cord-015369-72cjogxz 1460 1 To to TO cord-015369-72cjogxz 1460 2 enhance enhance VB cord-015369-72cjogxz 1460 3 diagnosis diagnosis NN cord-015369-72cjogxz 1460 4 of of IN cord-015369-72cjogxz 1460 5 acute acute JJ cord-015369-72cjogxz 1460 6 appendicitis appendicitis NN cord-015369-72cjogxz 1460 7 in in IN cord-015369-72cjogxz 1460 8 patients patient NNS cord-015369-72cjogxz 1460 9 with with IN cord-015369-72cjogxz 1460 10 increased increase VBN cord-015369-72cjogxz 1460 11 BMI BMI NNP cord-015369-72cjogxz 1460 12 ( ( -LRB- cord-015369-72cjogxz 1460 13 ! ! . cord-015369-72cjogxz 1460 14 30 30 CD cord-015369-72cjogxz 1460 15 kg kg NN cord-015369-72cjogxz 1460 16 / / SYM cord-015369-72cjogxz 1460 17 m m NN cord-015369-72cjogxz 1460 18 2 2 CD cord-015369-72cjogxz 1460 19 ) ) -RRB- cord-015369-72cjogxz 1460 20 suffering suffer VBG cord-015369-72cjogxz 1460 21 from from IN cord-015369-72cjogxz 1460 22 acute acute JJ cord-015369-72cjogxz 1460 23 pain pain NN cord-015369-72cjogxz 1460 24 in in IN cord-015369-72cjogxz 1460 25 the the DT cord-015369-72cjogxz 1460 26 right right JJ cord-015369-72cjogxz 1460 27 underbelly underbelly JJ cord-015369-72cjogxz 1460 28 and and CC cord-015369-72cjogxz 1460 29 short short JJ cord-015369-72cjogxz 1460 30 duration duration NN cord-015369-72cjogxz 1460 31 of of IN cord-015369-72cjogxz 1460 32 anamnesis anamnesis NN cord-015369-72cjogxz 1460 33 , , , cord-015369-72cjogxz 1460 34 it -PRON- PRP cord-015369-72cjogxz 1460 35 is be VBZ cord-015369-72cjogxz 1460 36 advisable advisable JJ cord-015369-72cjogxz 1460 37 to to TO cord-015369-72cjogxz 1460 38 directly directly RB cord-015369-72cjogxz 1460 39 perform perform VB cord-015369-72cjogxz 1460 40 CT CT NNP cord-015369-72cjogxz 1460 41 of of IN cord-015369-72cjogxz 1460 42 the the DT cord-015369-72cjogxz 1460 43 abdomen abdomen NN cord-015369-72cjogxz 1460 44 instead instead RB cord-015369-72cjogxz 1460 45 of of IN cord-015369-72cjogxz 1460 46 ultrasound ultrasound NN cord-015369-72cjogxz 1460 47 imaging imaging NN cord-015369-72cjogxz 1460 48 . . . cord-015369-72cjogxz 1461 1 Outcome outcome NN cord-015369-72cjogxz 1461 2 of of IN cord-015369-72cjogxz 1461 3 emergency emergency NN cord-015369-72cjogxz 1461 4 bowel bowel NN cord-015369-72cjogxz 1461 5 resection resection NN cord-015369-72cjogxz 1461 6 for for IN cord-015369-72cjogxz 1461 7 acute acute JJ cord-015369-72cjogxz 1461 8 mesenteric mesenteric JJ cord-015369-72cjogxz 1461 9 ischemia ischemia NN cord-015369-72cjogxz 1461 10 Background background NN cord-015369-72cjogxz 1461 11 . . . cord-015369-72cjogxz 1462 1 Due due IN cord-015369-72cjogxz 1462 2 to to IN cord-015369-72cjogxz 1462 3 vague vague JJ cord-015369-72cjogxz 1462 4 early early JJ cord-015369-72cjogxz 1462 5 symptoms symptom NNS cord-015369-72cjogxz 1462 6 and and CC cord-015369-72cjogxz 1462 7 lacking lack VBG cord-015369-72cjogxz 1462 8 specific specific JJ cord-015369-72cjogxz 1462 9 laboratory laboratory NN cord-015369-72cjogxz 1462 10 values value NNS cord-015369-72cjogxz 1462 11 , , , cord-015369-72cjogxz 1462 12 acute acute JJ cord-015369-72cjogxz 1462 13 mesenteric mesenteric JJ cord-015369-72cjogxz 1462 14 ischemia ischemia NN cord-015369-72cjogxz 1462 15 ( ( -LRB- cord-015369-72cjogxz 1462 16 AMI AMI NNP cord-015369-72cjogxz 1462 17 ) ) -RRB- cord-015369-72cjogxz 1462 18 is be VBZ cord-015369-72cjogxz 1462 19 often often RB cord-015369-72cjogxz 1462 20 detected detect VBN cord-015369-72cjogxz 1462 21 late late RB cord-015369-72cjogxz 1462 22 when when WRB cord-015369-72cjogxz 1462 23 bowel bowel NN cord-015369-72cjogxz 1462 24 necrosis necrosis NN cord-015369-72cjogxz 1462 25 has have VBZ cord-015369-72cjogxz 1462 26 occurred occur VBN cord-015369-72cjogxz 1462 27 . . . cord-015369-72cjogxz 1463 1 Methods method NNS cord-015369-72cjogxz 1463 2 . . . cord-015369-72cjogxz 1464 1 In in IN cord-015369-72cjogxz 1464 2 a a DT cord-015369-72cjogxz 1464 3 75-month 75-month CD cord-015369-72cjogxz 1464 4 period period NN cord-015369-72cjogxz 1464 5 , , , cord-015369-72cjogxz 1464 6 all all DT cord-015369-72cjogxz 1464 7 consecutive consecutive JJ cord-015369-72cjogxz 1464 8 patients patient NNS cord-015369-72cjogxz 1464 9 with with IN cord-015369-72cjogxz 1464 10 clinical clinical JJ cord-015369-72cjogxz 1464 11 symptoms symptom NNS cord-015369-72cjogxz 1464 12 of of IN cord-015369-72cjogxz 1464 13 mesenteric mesenteric JJ cord-015369-72cjogxz 1464 14 ischemia ischemia NN cord-015369-72cjogxz 1464 15 were be VBD cord-015369-72cjogxz 1464 16 screened screen VBN cord-015369-72cjogxz 1464 17 for for IN cord-015369-72cjogxz 1464 18 inclusion inclusion NN cord-015369-72cjogxz 1464 19 in in IN cord-015369-72cjogxz 1464 20 this this DT cord-015369-72cjogxz 1464 21 retrospective retrospective JJ cord-015369-72cjogxz 1464 22 study study NN cord-015369-72cjogxz 1464 23 . . . cord-015369-72cjogxz 1465 1 Patients patient NNS cord-015369-72cjogxz 1465 2 with with IN cord-015369-72cjogxz 1465 3 secondary secondary JJ cord-015369-72cjogxz 1465 4 causes cause NNS cord-015369-72cjogxz 1465 5 for for IN cord-015369-72cjogxz 1465 6 ischemia ischemia NN cord-015369-72cjogxz 1465 7 ( ( -LRB- cord-015369-72cjogxz 1465 8 strangulation strangulation NN cord-015369-72cjogxz 1465 9 ileus ileus NNP cord-015369-72cjogxz 1465 10 / / SYM cord-015369-72cjogxz 1465 11 post post NN cord-015369-72cjogxz 1465 12 resection resection NN cord-015369-72cjogxz 1465 13 ) ) -RRB- cord-015369-72cjogxz 1465 14 were be VBD cord-015369-72cjogxz 1465 15 excluded exclude VBN cord-015369-72cjogxz 1465 16 . . . cord-015369-72cjogxz 1466 1 Results result NNS cord-015369-72cjogxz 1466 2 are be VBP cord-015369-72cjogxz 1466 3 reported report VBN cord-015369-72cjogxz 1466 4 as as IN cord-015369-72cjogxz 1466 5 mean mean JJ cord-015369-72cjogxz 1466 6 AE AE NNP cord-015369-72cjogxz 1466 7 SD SD NNP cord-015369-72cjogxz 1466 8 or or CC cord-015369-72cjogxz 1466 9 total total JJ cord-015369-72cjogxz 1466 10 number number NN cord-015369-72cjogxz 1466 11 ( ( -LRB- cord-015369-72cjogxz 1466 12 % % NN cord-015369-72cjogxz 1466 13 ) ) -RRB- cord-015369-72cjogxz 1466 14 . . . cord-015369-72cjogxz 1467 1 Results result NNS cord-015369-72cjogxz 1467 2 . . . cord-015369-72cjogxz 1468 1 Sixty sixty CD cord-015369-72cjogxz 1468 2 - - HYPH cord-015369-72cjogxz 1468 3 two two CD cord-015369-72cjogxz 1468 4 patients patient NNS cord-015369-72cjogxz 1468 5 ( ( -LRB- cord-015369-72cjogxz 1468 6 54.8 54.8 CD cord-015369-72cjogxz 1468 7 % % NN cord-015369-72cjogxz 1468 8 female female NN cord-015369-72cjogxz 1468 9 ; ; : cord-015369-72cjogxz 1468 10 mean mean VB cord-015369-72cjogxz 1468 11 age age NN cord-015369-72cjogxz 1468 12 72.34 72.34 CD cord-015369-72cjogxz 1468 13 AE AE NNP cord-015369-72cjogxz 1468 14 15.71 15.71 CD cord-015369-72cjogxz 1468 15 years year NNS cord-015369-72cjogxz 1468 16 ) ) -RRB- cord-015369-72cjogxz 1468 17 were be VBD cord-015369-72cjogxz 1468 18 enrolled enrol VBN cord-015369-72cjogxz 1468 19 . . . cord-015369-72cjogxz 1469 1 Twenty twenty CD cord-015369-72cjogxz 1469 2 - - HYPH cord-015369-72cjogxz 1469 3 two two CD cord-015369-72cjogxz 1469 4 patients patient NNS cord-015369-72cjogxz 1469 5 ( ( -LRB- cord-015369-72cjogxz 1469 6 34.4 34.4 CD cord-015369-72cjogxz 1469 7 % % NN cord-015369-72cjogxz 1469 8 ) ) -RRB- cord-015369-72cjogxz 1469 9 had have VBD cord-015369-72cjogxz 1469 10 preoperative preoperative JJ cord-015369-72cjogxz 1469 11 arrhythmia arrhythmia NN cord-015369-72cjogxz 1469 12 . . . cord-015369-72cjogxz 1470 1 Lactate lactate NN cord-015369-72cjogxz 1470 2 levels level NNS cord-015369-72cjogxz 1470 3 upon upon IN cord-015369-72cjogxz 1470 4 diagnosis diagnosis NN cord-015369-72cjogxz 1470 5 were be VBD cord-015369-72cjogxz 1470 6 40.67 40.67 CD cord-015369-72cjogxz 1470 7 AE AE NNP cord-015369-72cjogxz 1470 8 25.06 25.06 CD cord-015369-72cjogxz 1470 9 mg mg NNP cord-015369-72cjogxz 1470 10 / / SYM cord-015369-72cjogxz 1470 11 dl dl NNP cord-015369-72cjogxz 1470 12 , , , cord-015369-72cjogxz 1470 13 leucocyte leucocyte NNP cord-015369-72cjogxz 1470 14 count count NNP cord-015369-72cjogxz 1470 15 15.15 15.15 CD cord-015369-72cjogxz 1470 16 AE AE NNP cord-015369-72cjogxz 1470 17 7.85 7.85 CD cord-015369-72cjogxz 1470 18 G g NN cord-015369-72cjogxz 1470 19 / / SYM cord-015369-72cjogxz 1470 20 l l NN cord-015369-72cjogxz 1470 21 and and CC cord-015369-72cjogxz 1470 22 creactive creactive NNP cord-015369-72cjogxz 1470 23 protein protein NN cord-015369-72cjogxz 1470 24 9.09 9.09 CD cord-015369-72cjogxz 1470 25 AE AE NNP cord-015369-72cjogxz 1470 26 3.32 3.32 CD cord-015369-72cjogxz 1470 27 mg mg NNP cord-015369-72cjogxz 1470 28 / / SYM cord-015369-72cjogxz 1470 29 dl dl NNP cord-015369-72cjogxz 1470 30 . . . cord-015369-72cjogxz 1471 1 Fifty fifty CD cord-015369-72cjogxz 1471 2 - - HYPH cord-015369-72cjogxz 1471 3 one one CD cord-015369-72cjogxz 1471 4 patients patient NNS cord-015369-72cjogxz 1471 5 ( ( -LRB- cord-015369-72cjogxz 1471 6 79.7 79.7 CD cord-015369-72cjogxz 1471 7 % % NN cord-015369-72cjogxz 1471 8 ) ) -RRB- cord-015369-72cjogxz 1471 9 underwent undergo VBD cord-015369-72cjogxz 1471 10 a a DT cord-015369-72cjogxz 1471 11 CT CT NNP cord-015369-72cjogxz 1471 12 scan scan NN cord-015369-72cjogxz 1471 13 , , , cord-015369-72cjogxz 1471 14 22 22 CD cord-015369-72cjogxz 1471 15 ( ( -LRB- cord-015369-72cjogxz 1471 16 34.4 34.4 CD cord-015369-72cjogxz 1471 17 % % NN cord-015369-72cjogxz 1471 18 ) ) -RRB- cord-015369-72cjogxz 1471 19 an an DT cord-015369-72cjogxz 1471 20 ultrasound ultrasound NN cord-015369-72cjogxz 1471 21 and and CC cord-015369-72cjogxz 1471 22 6 6 CD cord-015369-72cjogxz 1471 23 ( ( -LRB- cord-015369-72cjogxz 1471 24 9.8 9.8 CD cord-015369-72cjogxz 1471 25 % % NN cord-015369-72cjogxz 1471 26 ) ) -RRB- cord-015369-72cjogxz 1471 27 an an DT cord-015369-72cjogxz 1471 28 angiography angiography NN cord-015369-72cjogxz 1471 29 , , , cord-015369-72cjogxz 1471 30 which which WDT cord-015369-72cjogxz 1471 31 diagnosed diagnose VBD cord-015369-72cjogxz 1471 32 mesenteric mesenteric JJ cord-015369-72cjogxz 1471 33 vessel vessel NN cord-015369-72cjogxz 1471 34 occlusion occlusion NN cord-015369-72cjogxz 1471 35 in in IN cord-015369-72cjogxz 1471 36 26 26 CD cord-015369-72cjogxz 1471 37 ( ( -LRB- cord-015369-72cjogxz 1471 38 41.94 41.94 CD cord-015369-72cjogxz 1471 39 % % NN cord-015369-72cjogxz 1471 40 ) ) -RRB- cord-015369-72cjogxz 1471 41 . . . cord-015369-72cjogxz 1472 1 Fifty fifty CD cord-015369-72cjogxz 1472 2 - - HYPH cord-015369-72cjogxz 1472 3 five five CD cord-015369-72cjogxz 1472 4 patients patient NNS cord-015369-72cjogxz 1472 5 ( ( -LRB- cord-015369-72cjogxz 1472 6 88.71 88.71 CD cord-015369-72cjogxz 1472 7 % % NN cord-015369-72cjogxz 1472 8 ) ) -RRB- cord-015369-72cjogxz 1472 9 underwent undergo VBD cord-015369-72cjogxz 1472 10 surgery surgery NN cord-015369-72cjogxz 1472 11 , , , cord-015369-72cjogxz 1472 12 five five CD cord-015369-72cjogxz 1472 13 patients patient NNS cord-015369-72cjogxz 1472 14 ( ( -LRB- cord-015369-72cjogxz 1472 15 8.06 8.06 CD cord-015369-72cjogxz 1472 16 % % NN cord-015369-72cjogxz 1472 17 ) ) -RRB- cord-015369-72cjogxz 1472 18 were be VBD cord-015369-72cjogxz 1472 19 managed manage VBN cord-015369-72cjogxz 1472 20 non non RB cord-015369-72cjogxz 1472 21 - - JJ cord-015369-72cjogxz 1472 22 operatively operatively RB cord-015369-72cjogxz 1472 23 , , , cord-015369-72cjogxz 1472 24 and and CC cord-015369-72cjogxz 1472 25 two two CD cord-015369-72cjogxz 1472 26 patients patient NNS cord-015369-72cjogxz 1472 27 ( ( -LRB- cord-015369-72cjogxz 1472 28 3.23 3.23 CD cord-015369-72cjogxz 1472 29 % % NN cord-015369-72cjogxz 1472 30 ) ) -RRB- cord-015369-72cjogxz 1472 31 died die VBD cord-015369-72cjogxz 1472 32 before before IN cord-015369-72cjogxz 1472 33 surgery surgery NN cord-015369-72cjogxz 1472 34 . . . cord-015369-72cjogxz 1473 1 Revascularization Revascularization NNP cord-015369-72cjogxz 1473 2 was be VBD cord-015369-72cjogxz 1473 3 only only RB cord-015369-72cjogxz 1473 4 possible possible JJ cord-015369-72cjogxz 1473 5 in in IN cord-015369-72cjogxz 1473 6 2 2 CD cord-015369-72cjogxz 1473 7 patients patient NNS cord-015369-72cjogxz 1473 8 ( ( -LRB- cord-015369-72cjogxz 1473 9 3.23 3.23 CD cord-015369-72cjogxz 1473 10 % % NN cord-015369-72cjogxz 1473 11 ) ) -RRB- cord-015369-72cjogxz 1473 12 . . . cord-015369-72cjogxz 1474 1 Forty forty CD cord-015369-72cjogxz 1474 2 - - HYPH cord-015369-72cjogxz 1474 3 five five CD cord-015369-72cjogxz 1474 4 patients patient NNS cord-015369-72cjogxz 1474 5 ( ( -LRB- cord-015369-72cjogxz 1474 6 81.82 81.82 CD cord-015369-72cjogxz 1474 7 % % NN cord-015369-72cjogxz 1474 8 of of IN cord-015369-72cjogxz 1474 9 operated operate VBN cord-015369-72cjogxz 1474 10 patients patient NNS cord-015369-72cjogxz 1474 11 ) ) -RRB- cord-015369-72cjogxz 1474 12 underwent undergo VBD cord-015369-72cjogxz 1474 13 bowel bowel NN cord-015369-72cjogxz 1474 14 resection resection NN cord-015369-72cjogxz 1474 15 , , , cord-015369-72cjogxz 1474 16 with with IN cord-015369-72cjogxz 1474 17 primary primary JJ cord-015369-72cjogxz 1474 18 anastomosis anastomosis NN cord-015369-72cjogxz 1474 19 in in IN cord-015369-72cjogxz 1474 20 20 20 CD cord-015369-72cjogxz 1474 21 and and CC cord-015369-72cjogxz 1474 22 stoma stoma NN cord-015369-72cjogxz 1474 23 creation creation NN cord-015369-72cjogxz 1474 24 in in IN cord-015369-72cjogxz 1474 25 25 25 CD cord-015369-72cjogxz 1474 26 patients patient NNS cord-015369-72cjogxz 1474 27 . . . cord-015369-72cjogxz 1475 1 Second second JJ cord-015369-72cjogxz 1475 2 look look NN cord-015369-72cjogxz 1475 3 operation operation NN cord-015369-72cjogxz 1475 4 was be VBD cord-015369-72cjogxz 1475 5 performed perform VBN cord-015369-72cjogxz 1475 6 in in IN cord-015369-72cjogxz 1475 7 9 9 CD cord-015369-72cjogxz 1475 8 patients patient NNS cord-015369-72cjogxz 1475 9 ( ( -LRB- cord-015369-72cjogxz 1475 10 14.80 14.80 CD cord-015369-72cjogxz 1475 11 % % NN cord-015369-72cjogxz 1475 12 ) ) -RRB- cord-015369-72cjogxz 1475 13 . . . cord-015369-72cjogxz 1476 1 In in IN cord-015369-72cjogxz 1476 2 - - HYPH cord-015369-72cjogxz 1476 3 hospital hospital NN cord-015369-72cjogxz 1476 4 mortality mortality NN cord-015369-72cjogxz 1476 5 was be VBD cord-015369-72cjogxz 1476 6 38.71 38.71 CD cord-015369-72cjogxz 1476 7 % % NN cord-015369-72cjogxz 1476 8 ( ( -LRB- cord-015369-72cjogxz 1476 9 24 24 CD cord-015369-72cjogxz 1476 10 patients patient NNS cord-015369-72cjogxz 1476 11 ) ) -RRB- cord-015369-72cjogxz 1476 12 . . . cord-015369-72cjogxz 1477 1 Preoperative Preoperative NNP cord-015369-72cjogxz 1477 2 arrhythmia arrhythmia NN cord-015369-72cjogxz 1478 1 ( ( -LRB- cord-015369-72cjogxz 1478 2 p p NN cord-015369-72cjogxz 1478 3 ¼ ¼ CD cord-015369-72cjogxz 1478 4 0.005 0.005 CD cord-015369-72cjogxz 1478 5 ) ) -RRB- cord-015369-72cjogxz 1478 6 , , , cord-015369-72cjogxz 1478 7 renal renal JJ cord-015369-72cjogxz 1478 8 failure failure NN cord-015369-72cjogxz 1478 9 ( ( -LRB- cord-015369-72cjogxz 1478 10 p p NN cord-015369-72cjogxz 1478 11 ¼ ¼ CD cord-015369-72cjogxz 1478 12 0.006 0.006 CD cord-015369-72cjogxz 1478 13 ) ) -RRB- cord-015369-72cjogxz 1478 14 , , , cord-015369-72cjogxz 1478 15 vasopressor vasopressor NN cord-015369-72cjogxz 1478 16 demand demand NN cord-015369-72cjogxz 1478 17 ( ( -LRB- cord-015369-72cjogxz 1478 18 p p NN cord-015369-72cjogxz 1478 19 ¼ ¼ CD cord-015369-72cjogxz 1478 20 0.005 0.005 CD cord-015369-72cjogxz 1478 21 ) ) -RRB- cord-015369-72cjogxz 1478 22 , , , cord-015369-72cjogxz 1478 23 intraoperatively intraoperatively RB cord-015369-72cjogxz 1478 24 instable instable JJ cord-015369-72cjogxz 1478 25 patients patient NNS cord-015369-72cjogxz 1478 26 ( ( -LRB- cord-015369-72cjogxz 1478 27 p p NN cord-015369-72cjogxz 1478 28 ¼ ¼ NNP cord-015369-72cjogxz 1478 29 0.011 0.011 CD cord-015369-72cjogxz 1478 30 ) ) -RRB- cord-015369-72cjogxz 1478 31 , , , cord-015369-72cjogxz 1478 32 diffuse diffuse VB cord-015369-72cjogxz 1478 33 bowel bowel NN cord-015369-72cjogxz 1478 34 ischemia ischemia NN cord-015369-72cjogxz 1478 35 without without IN cord-015369-72cjogxz 1478 36 resection resection NN cord-015369-72cjogxz 1478 37 ( ( -LRB- cord-015369-72cjogxz 1478 38 p p NN cord-015369-72cjogxz 1478 39 ¼ ¼ CD cord-015369-72cjogxz 1478 40 0.02 0.02 CD cord-015369-72cjogxz 1478 41 ) ) -RRB- cord-015369-72cjogxz 1478 42 , , , cord-015369-72cjogxz 1478 43 and and CC cord-015369-72cjogxz 1478 44 bowel bowel NN cord-015369-72cjogxz 1478 45 resection resection NN cord-015369-72cjogxz 1478 46 during during IN cord-015369-72cjogxz 1478 47 second second JJ cord-015369-72cjogxz 1478 48 look look NN cord-015369-72cjogxz 1478 49 operation operation NN cord-015369-72cjogxz 1478 50 ( ( -LRB- cord-015369-72cjogxz 1478 51 p p NN cord-015369-72cjogxz 1478 52 ¼ ¼ CD cord-015369-72cjogxz 1478 53 0.025 0.025 CD cord-015369-72cjogxz 1478 54 ) ) -RRB- cord-015369-72cjogxz 1478 55 were be VBD cord-015369-72cjogxz 1478 56 associated associate VBN cord-015369-72cjogxz 1478 57 with with IN cord-015369-72cjogxz 1478 58 mortality mortality NN cord-015369-72cjogxz 1478 59 . . . cord-015369-72cjogxz 1479 1 Conclusions conclusion NNS cord-015369-72cjogxz 1479 2 . . . cord-015369-72cjogxz 1480 1 Despite despite IN cord-015369-72cjogxz 1480 2 modern modern JJ cord-015369-72cjogxz 1480 3 diagnostic diagnostic JJ cord-015369-72cjogxz 1480 4 tools tool NNS cord-015369-72cjogxz 1480 5 , , , cord-015369-72cjogxz 1480 6 acute acute JJ cord-015369-72cjogxz 1480 7 mesenteric mesenteric JJ cord-015369-72cjogxz 1480 8 ischemia ischemia NN cord-015369-72cjogxz 1480 9 is be VBZ cord-015369-72cjogxz 1480 10 still still RB cord-015369-72cjogxz 1480 11 often often RB cord-015369-72cjogxz 1480 12 diagnosed diagnose VBN cord-015369-72cjogxz 1480 13 late late RB cord-015369-72cjogxz 1480 14 . . . cord-015369-72cjogxz 1481 1 Mortality mortality NN cord-015369-72cjogxz 1481 2 remains remain VBZ cord-015369-72cjogxz 1481 3 high high JJ cord-015369-72cjogxz 1481 4 in in IN cord-015369-72cjogxz 1481 5 unstable unstable JJ cord-015369-72cjogxz 1481 6 patients patient NNS cord-015369-72cjogxz 1481 7 , , , cord-015369-72cjogxz 1481 8 or or CC cord-015369-72cjogxz 1481 9 when when WRB cord-015369-72cjogxz 1481 10 no no DT cord-015369-72cjogxz 1481 11 resection resection NN cord-015369-72cjogxz 1481 12 of of IN cord-015369-72cjogxz 1481 13 necrotic necrotic JJ cord-015369-72cjogxz 1481 14 bowel bowel NN cord-015369-72cjogxz 1481 15 is be VBZ cord-015369-72cjogxz 1481 16 possible possible JJ cord-015369-72cjogxz 1481 17 during during IN cord-015369-72cjogxz 1481 18 primary primary JJ cord-015369-72cjogxz 1481 19 surgery surgery NN cord-015369-72cjogxz 1481 20 . . . cord-015369-72cjogxz 1482 1 Background background NN cord-015369-72cjogxz 1482 2 . . . cord-015369-72cjogxz 1483 1 Intrahepatic intrahepatic JJ cord-015369-72cjogxz 1483 2 cholangiocellular cholangiocellular NN cord-015369-72cjogxz 1483 3 carcinoma carcinoma NN cord-015369-72cjogxz 1483 4 ( ( -LRB- cord-015369-72cjogxz 1483 5 ICC ICC NNP cord-015369-72cjogxz 1483 6 ) ) -RRB- cord-015369-72cjogxz 1483 7 accounts account VBZ cord-015369-72cjogxz 1483 8 for for IN cord-015369-72cjogxz 1483 9 10 10 CD cord-015369-72cjogxz 1483 10 % % NN cord-015369-72cjogxz 1483 11 to to TO cord-015369-72cjogxz 1483 12 20 20 CD cord-015369-72cjogxz 1483 13 % % NN cord-015369-72cjogxz 1483 14 of of IN cord-015369-72cjogxz 1483 15 primary primary JJ cord-015369-72cjogxz 1483 16 liver liver NN cord-015369-72cjogxz 1483 17 cancer cancer NN cord-015369-72cjogxz 1483 18 cases case NNS cord-015369-72cjogxz 1483 19 . . . cord-015369-72cjogxz 1484 1 Aggressive aggressive JJ cord-015369-72cjogxz 1484 2 resection resection NN cord-015369-72cjogxz 1484 3 is be VBZ cord-015369-72cjogxz 1484 4 the the DT cord-015369-72cjogxz 1484 5 mainstay mainstay NN cord-015369-72cjogxz 1484 6 of of IN cord-015369-72cjogxz 1484 7 treatment treatment NN cord-015369-72cjogxz 1484 8 . . . cord-015369-72cjogxz 1485 1 Methods method NNS cord-015369-72cjogxz 1485 2 . . . cord-015369-72cjogxz 1486 1 Between between IN cord-015369-72cjogxz 1486 2 2001 2001 CD cord-015369-72cjogxz 1486 3 and and CC cord-015369-72cjogxz 1486 4 2007 2007 CD cord-015369-72cjogxz 1486 5 total total JJ cord-015369-72cjogxz 1486 6 25 25 CD cord-015369-72cjogxz 1486 7 patients patient NNS cord-015369-72cjogxz 1486 8 ( ( -LRB- cord-015369-72cjogxz 1486 9 68 68 CD cord-015369-72cjogxz 1486 10 % % NN cord-015369-72cjogxz 1486 11 male male NN cord-015369-72cjogxz 1486 12 , , , cord-015369-72cjogxz 1486 13 mean mean VB cord-015369-72cjogxz 1487 1 age age NN cord-015369-72cjogxz 1487 2 62.5 62.5 CD cord-015369-72cjogxz 1487 3 ( ( -LRB- cord-015369-72cjogxz 1487 4 AE7.4 AE7.4 NNP cord-015369-72cjogxz 1487 5 ) ) -RRB- cord-015369-72cjogxz 1487 6 years year NNS cord-015369-72cjogxz 1487 7 ) ) -RRB- cord-015369-72cjogxz 1487 8 operated operate VBD cord-015369-72cjogxz 1487 9 for for IN cord-015369-72cjogxz 1487 10 ICC ICC NNP cord-015369-72cjogxz 1487 11 at at IN cord-015369-72cjogxz 1487 12 our -PRON- PRP$ cord-015369-72cjogxz 1487 13 department department NN cord-015369-72cjogxz 1487 14 were be VBD cord-015369-72cjogxz 1487 15 followed follow VBN cord-015369-72cjogxz 1487 16 up up RP cord-015369-72cjogxz 1487 17 postoperatively postoperatively RB cord-015369-72cjogxz 1487 18 . . . cord-015369-72cjogxz 1488 1 Eleven eleven JJ cord-015369-72cjogxz 1488 2 right right JJ cord-015369-72cjogxz 1488 3 hemihepatectomies hemihepatectomie NNS cord-015369-72cjogxz 1488 4 ( ( -LRB- cord-015369-72cjogxz 1488 5 eight eight CD cord-015369-72cjogxz 1488 6 extended extended JJ cord-015369-72cjogxz 1488 7 ) ) -RRB- cord-015369-72cjogxz 1488 8 , , , cord-015369-72cjogxz 1488 9 seven seven CD cord-015369-72cjogxz 1488 10 left left JJ cord-015369-72cjogxz 1488 11 hemihepatectomies hemihepatectomie NNS cord-015369-72cjogxz 1488 12 ( ( -LRB- cord-015369-72cjogxz 1488 13 three three CD cord-015369-72cjogxz 1488 14 extended extended JJ cord-015369-72cjogxz 1488 15 ) ) -RRB- cord-015369-72cjogxz 1488 16 , , , cord-015369-72cjogxz 1488 17 one one CD cord-015369-72cjogxz 1488 18 segmental segmental JJ cord-015369-72cjogxz 1488 19 resection resection NN cord-015369-72cjogxz 1488 20 , , , cord-015369-72cjogxz 1488 21 two two CD cord-015369-72cjogxz 1488 22 bisegmentectomies bisegmentectomie NNS cord-015369-72cjogxz 1488 23 ( ( -LRB- cord-015369-72cjogxz 1488 24 II II NNP cord-015369-72cjogxz 1488 25 III III NNP cord-015369-72cjogxz 1488 26 ) ) -RRB- cord-015369-72cjogxz 1488 27 , , , cord-015369-72cjogxz 1488 28 and and CC cord-015369-72cjogxz 1488 29 four four CD cord-015369-72cjogxz 1488 30 non non JJ cord-015369-72cjogxz 1488 31 - - JJ cord-015369-72cjogxz 1488 32 anatomical anatomical JJ cord-015369-72cjogxz 1488 33 resections resection NNS cord-015369-72cjogxz 1488 34 were be VBD cord-015369-72cjogxz 1488 35 performed perform VBN cord-015369-72cjogxz 1488 36 . . . cord-015369-72cjogxz 1489 1 The the DT cord-015369-72cjogxz 1489 2 median median JJ cord-015369-72cjogxz 1489 3 observation observation NN cord-015369-72cjogxz 1489 4 period period NN cord-015369-72cjogxz 1489 5 was be VBD cord-015369-72cjogxz 1489 6 2.7 2.7 CD cord-015369-72cjogxz 1489 7 ( ( -LRB- cord-015369-72cjogxz 1489 8 range range NN cord-015369-72cjogxz 1489 9 : : : cord-015369-72cjogxz 1489 10 0.2 0.2 CD cord-015369-72cjogxz 1489 11 - - HYPH cord-015369-72cjogxz 1489 12 6.9 6.9 CD cord-015369-72cjogxz 1489 13 ) ) -RRB- cord-015369-72cjogxz 1489 14 years year NNS cord-015369-72cjogxz 1489 15 . . . cord-015369-72cjogxz 1490 1 Analysis analysis NN cord-015369-72cjogxz 1490 2 focused focus VBN cord-015369-72cjogxz 1490 3 on on IN cord-015369-72cjogxz 1490 4 age age NN cord-015369-72cjogxz 1490 5 , , , cord-015369-72cjogxz 1490 6 sex sex NN cord-015369-72cjogxz 1490 7 , , , cord-015369-72cjogxz 1490 8 tumor tumor NN cord-015369-72cjogxz 1490 9 size size NN cord-015369-72cjogxz 1490 10 , , , cord-015369-72cjogxz 1490 11 operating operating NN cord-015369-72cjogxz 1490 12 time time NN cord-015369-72cjogxz 1490 13 , , , cord-015369-72cjogxz 1490 14 histologic histologic JJ cord-015369-72cjogxz 1490 15 resection resection NN cord-015369-72cjogxz 1490 16 margin margin NN cord-015369-72cjogxz 1490 17 , , , cord-015369-72cjogxz 1490 18 tumor tumor NN cord-015369-72cjogxz 1490 19 - - HYPH cord-015369-72cjogxz 1490 20 node node NN cord-015369-72cjogxz 1490 21 - - HYPH cord-015369-72cjogxz 1490 22 metastasis metastasis NN cord-015369-72cjogxz 1491 1 ( ( -LRB- cord-015369-72cjogxz 1491 2 TNM TNM NNP cord-015369-72cjogxz 1491 3 ) ) -RRB- cord-015369-72cjogxz 1491 4 stage stage NN cord-015369-72cjogxz 1491 5 , , , cord-015369-72cjogxz 1491 6 reoperations reoperation NNS cord-015369-72cjogxz 1491 7 , , , cord-015369-72cjogxz 1491 8 postoperative postoperative JJ cord-015369-72cjogxz 1491 9 complications complication NNS cord-015369-72cjogxz 1491 10 , , , cord-015369-72cjogxz 1491 11 tumor tumor NN cord-015369-72cjogxz 1491 12 recurrence recurrence NN cord-015369-72cjogxz 1491 13 , , , cord-015369-72cjogxz 1491 14 survival survival NN cord-015369-72cjogxz 1491 15 rate rate NN cord-015369-72cjogxz 1491 16 . . . cord-015369-72cjogxz 1492 1 We -PRON- PRP cord-015369-72cjogxz 1492 2 also also RB cord-015369-72cjogxz 1492 3 assessed assess VBD cord-015369-72cjogxz 1492 4 p53 p53 NN cord-015369-72cjogxz 1492 5 protein protein NN cord-015369-72cjogxz 1492 6 accumulation accumulation NN cord-015369-72cjogxz 1492 7 , , , cord-015369-72cjogxz 1492 8 ki67 ki67 NNP cord-015369-72cjogxz 1492 9 index index NN cord-015369-72cjogxz 1492 10 and and CC cord-015369-72cjogxz 1492 11 MUC1 MUC1 NNP cord-015369-72cjogxz 1492 12 positivity positivity NN cord-015369-72cjogxz 1492 13 . . . cord-015369-72cjogxz 1493 1 Results result NNS cord-015369-72cjogxz 1493 2 . . . cord-015369-72cjogxz 1494 1 Median median JJ cord-015369-72cjogxz 1494 2 operating operating NN cord-015369-72cjogxz 1494 3 time time NN cord-015369-72cjogxz 1494 4 was be VBD cord-015369-72cjogxz 1494 5 4.5 4.5 CD cord-015369-72cjogxz 1494 6 h. h. NN cord-015369-72cjogxz 1494 7 Mean mean JJ cord-015369-72cjogxz 1494 8 diameter diameter NN cord-015369-72cjogxz 1494 9 of of IN cord-015369-72cjogxz 1494 10 the the DT cord-015369-72cjogxz 1494 11 resected resected JJ cord-015369-72cjogxz 1494 12 tumor tumor NN cord-015369-72cjogxz 1494 13 was be VBD cord-015369-72cjogxz 1494 14 7.55 7.55 CD cord-015369-72cjogxz 1494 15 ( ( -LRB- cord-015369-72cjogxz 1494 16 range range NN cord-015369-72cjogxz 1494 17 : : : cord-015369-72cjogxz 1494 18 2.5 2.5 CD cord-015369-72cjogxz 1494 19 - - SYM cord-015369-72cjogxz 1494 20 17 17 CD cord-015369-72cjogxz 1494 21 ) ) -RRB- cord-015369-72cjogxz 1494 22 cm cm NNP cord-015369-72cjogxz 1494 23 . . . cord-015369-72cjogxz 1495 1 Histology histology NN cord-015369-72cjogxz 1495 2 showed show VBD cord-015369-72cjogxz 1495 3 R1 r1 NN cord-015369-72cjogxz 1495 4 resection resection NN cord-015369-72cjogxz 1495 5 for for IN cord-015369-72cjogxz 1495 6 three three CD cord-015369-72cjogxz 1495 7 patients patient NNS cord-015369-72cjogxz 1495 8 . . . cord-015369-72cjogxz 1496 1 Eighteen eighteen CD cord-015369-72cjogxz 1496 2 patients patient NNS cord-015369-72cjogxz 1496 3 ( ( -LRB- cord-015369-72cjogxz 1496 4 72 72 CD cord-015369-72cjogxz 1496 5 % % NN cord-015369-72cjogxz 1496 6 ) ) -RRB- cord-015369-72cjogxz 1496 7 underwent undergo VBD cord-015369-72cjogxz 1496 8 lymph lymph NN cord-015369-72cjogxz 1496 9 node node NN cord-015369-72cjogxz 1496 10 dissection dissection NN cord-015369-72cjogxz 1496 11 . . . cord-015369-72cjogxz 1497 1 Major major JJ cord-015369-72cjogxz 1497 2 postoperative postoperative JJ cord-015369-72cjogxz 1497 3 complications complication NNS cord-015369-72cjogxz 1497 4 occurred occur VBD cord-015369-72cjogxz 1497 5 in in IN cord-015369-72cjogxz 1497 6 ten ten CD cord-015369-72cjogxz 1497 7 patients patient NNS cord-015369-72cjogxz 1497 8 ( ( -LRB- cord-015369-72cjogxz 1497 9 40 40 CD cord-015369-72cjogxz 1497 10 % % NN cord-015369-72cjogxz 1497 11 ) ) -RRB- cord-015369-72cjogxz 1497 12 . . . cord-015369-72cjogxz 1498 1 There there EX cord-015369-72cjogxz 1498 2 was be VBD cord-015369-72cjogxz 1498 3 one one CD cord-015369-72cjogxz 1498 4 in in IN cord-015369-72cjogxz 1498 5 - - HYPH cord-015369-72cjogxz 1498 6 hospital hospital NN cord-015369-72cjogxz 1498 7 death death NN cord-015369-72cjogxz 1498 8 from from IN cord-015369-72cjogxz 1498 9 liver liver NN cord-015369-72cjogxz 1498 10 failure failure NN cord-015369-72cjogxz 1498 11 . . . cord-015369-72cjogxz 1499 1 Seventeen seventeen CD cord-015369-72cjogxz 1499 2 patients patient NNS cord-015369-72cjogxz 1499 3 ( ( -LRB- cord-015369-72cjogxz 1499 4 68 68 CD cord-015369-72cjogxz 1499 5 % % NN cord-015369-72cjogxz 1499 6 ) ) -RRB- cord-015369-72cjogxz 1499 7 showed show VBD cord-015369-72cjogxz 1499 8 tumor tumor NN cord-015369-72cjogxz 1499 9 recurrence recurrence NN cord-015369-72cjogxz 1499 10 . . . cord-015369-72cjogxz 1500 1 Median median JJ cord-015369-72cjogxz 1500 2 time time NN cord-015369-72cjogxz 1500 3 to to TO cord-015369-72cjogxz 1500 4 tumor tumor NN cord-015369-72cjogxz 1500 5 recurrence recurrence NN cord-015369-72cjogxz 1500 6 was be VBD cord-015369-72cjogxz 1500 7 6.7 6.7 CD cord-015369-72cjogxz 1500 8 ( ( -LRB- cord-015369-72cjogxz 1500 9 5.7 5.7 CD cord-015369-72cjogxz 1500 10 - - SYM cord-015369-72cjogxz 1500 11 15.4 15.4 CD cord-015369-72cjogxz 1500 12 ) ) -RRB- cord-015369-72cjogxz 1500 13 months month NNS cord-015369-72cjogxz 1500 14 . . . cord-015369-72cjogxz 1501 1 Total total JJ cord-015369-72cjogxz 1501 2 12 12 CD cord-015369-72cjogxz 1501 3 patients patient NNS cord-015369-72cjogxz 1501 4 ( ( -LRB- cord-015369-72cjogxz 1501 5 48 48 CD cord-015369-72cjogxz 1501 6 % % NN cord-015369-72cjogxz 1501 7 ) ) -RRB- cord-015369-72cjogxz 1501 8 died die VBD cord-015369-72cjogxz 1501 9 . . . cord-015369-72cjogxz 1502 1 Median median JJ cord-015369-72cjogxz 1502 2 time time NN cord-015369-72cjogxz 1502 3 from from IN cord-015369-72cjogxz 1502 4 operation operation NN cord-015369-72cjogxz 1502 5 to to IN cord-015369-72cjogxz 1502 6 death death NN cord-015369-72cjogxz 1502 7 was be VBD cord-015369-72cjogxz 1502 8 14.6 14.6 CD cord-015369-72cjogxz 1502 9 ( ( -LRB- cord-015369-72cjogxz 1502 10 7.4 7.4 CD cord-015369-72cjogxz 1502 11 - - SYM cord-015369-72cjogxz 1502 12 30.9 30.9 CD cord-015369-72cjogxz 1502 13 ) ) -RRB- cord-015369-72cjogxz 1502 14 months month NNS cord-015369-72cjogxz 1502 15 . . . cord-015369-72cjogxz 1503 1 Survival survival NN cord-015369-72cjogxz 1503 2 rate rate NN cord-015369-72cjogxz 1503 3 after after IN cord-015369-72cjogxz 1503 4 one one CD cord-015369-72cjogxz 1503 5 year year NN cord-015369-72cjogxz 1503 6 was be VBD cord-015369-72cjogxz 1503 7 84 84 CD cord-015369-72cjogxz 1503 8 % % NN cord-015369-72cjogxz 1503 9 , , , cord-015369-72cjogxz 1503 10 after after IN cord-015369-72cjogxz 1503 11 three three CD cord-015369-72cjogxz 1503 12 years year NNS cord-015369-72cjogxz 1503 13 57 57 CD cord-015369-72cjogxz 1503 14 % % NN cord-015369-72cjogxz 1503 15 and and CC cord-015369-72cjogxz 1503 16 after after IN cord-015369-72cjogxz 1503 17 five five CD cord-015369-72cjogxz 1503 18 years year NNS cord-015369-72cjogxz 1503 19 45 45 CD cord-015369-72cjogxz 1503 20 % % NN cord-015369-72cjogxz 1503 21 . . . cord-015369-72cjogxz 1504 1 We -PRON- PRP cord-015369-72cjogxz 1504 2 found find VBD cord-015369-72cjogxz 1504 3 no no DT cord-015369-72cjogxz 1504 4 correlation correlation NN cord-015369-72cjogxz 1504 5 between between IN cord-015369-72cjogxz 1504 6 p53 p53 NN cord-015369-72cjogxz 1504 7 accumulation accumulation NN cord-015369-72cjogxz 1504 8 / / SYM cord-015369-72cjogxz 1504 9 high high JJ cord-015369-72cjogxz 1504 10 ki67 ki67 NNP cord-015369-72cjogxz 1504 11 index index NN cord-015369-72cjogxz 1504 12 counts count VBZ cord-015369-72cjogxz 1504 13 / / SYM cord-015369-72cjogxz 1504 14 MUC1 MUC1 NNP cord-015369-72cjogxz 1504 15 positivity positivity NN cord-015369-72cjogxz 1504 16 and and CC cord-015369-72cjogxz 1504 17 ICC ICC NNP cord-015369-72cjogxz 1504 18 prognosis prognosis NN cord-015369-72cjogxz 1504 19 . . . cord-015369-72cjogxz 1505 1 Conclusions conclusion NNS cord-015369-72cjogxz 1505 2 . . . cord-015369-72cjogxz 1506 1 Our -PRON- PRP$ cord-015369-72cjogxz 1506 2 study study NN cord-015369-72cjogxz 1506 3 shows show VBZ cord-015369-72cjogxz 1506 4 that that DT cord-015369-72cjogxz 1506 5 outcome outcome NN cord-015369-72cjogxz 1506 6 after after IN cord-015369-72cjogxz 1506 7 ICC ICC NNP cord-015369-72cjogxz 1506 8 is be VBZ cord-015369-72cjogxz 1506 9 generally generally RB cord-015369-72cjogxz 1506 10 poor poor JJ cord-015369-72cjogxz 1506 11 and and CC cord-015369-72cjogxz 1506 12 only only RB cord-015369-72cjogxz 1506 13 a a DT cord-015369-72cjogxz 1506 14 small small JJ cord-015369-72cjogxz 1506 15 number number NN cord-015369-72cjogxz 1506 16 of of IN cord-015369-72cjogxz 1506 17 patients patient NNS cord-015369-72cjogxz 1506 18 are be VBP cord-015369-72cjogxz 1506 19 really really RB cord-015369-72cjogxz 1506 20 cured cure VBN cord-015369-72cjogxz 1506 21 . . . cord-015369-72cjogxz 1507 1 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 1507 2 - - HYPH cord-015369-72cjogxz 1507 3 Ratio ratio NN cord-015369-72cjogxz 1507 4 als als NN cord-015369-72cjogxz 1507 5 prädiktiver prädiktiver NN cord-015369-72cjogxz 1508 1 Faktor Faktor NNP cord-015369-72cjogxz 1508 2 nach nach NNP cord-015369-72cjogxz 1508 3 kurativer kurativer NNP cord-015369-72cjogxz 1509 1 Resektion Resektion NNP cord-015369-72cjogxz 1509 2 wegen wegen NNP cord-015369-72cjogxz 1509 3 intrahepatalem intrahepatalem NNP cord-015369-72cjogxz 1510 1 Cholangiokarzinom Cholangiokarzinom NNP cord-015369-72cjogxz 1510 2 für für NNS cord-015369-72cjogxz 1510 3 die die VBP cord-015369-72cjogxz 1510 4 Lymphknotenchirurgie Lymphknotenchirurgie NNP cord-015369-72cjogxz 1510 5 , , , cord-015369-72cjogxz 1510 6 es es NNP cord-015369-72cjogxz 1510 7 konnte konnte NNP cord-015369-72cjogxz 1510 8 auch auch NNP cord-015369-72cjogxz 1510 9 bisher bisher NNP cord-015369-72cjogxz 1510 10 kein kein NNP cord-015369-72cjogxz 1510 11 Ü Ü NNP cord-015369-72cjogxz 1510 12 berlebensvorteil berlebensvorteil NNP cord-015369-72cjogxz 1510 13 für für NNP cord-015369-72cjogxz 1510 14 diese diese NNP cord-015369-72cjogxz 1510 15 Eingriffserweiterung Eingriffserweiterung NNP cord-015369-72cjogxz 1510 16 gezeigt gezeigt NNP cord-015369-72cjogxz 1510 17 werden werden NNP cord-015369-72cjogxz 1510 18 . . . cord-015369-72cjogxz 1511 1 Methodik Methodik NNP cord-015369-72cjogxz 1511 2 . . . cord-015369-72cjogxz 1512 1 Zwischen Zwischen NNP cord-015369-72cjogxz 1512 2 1997 1997 CD cord-015369-72cjogxz 1512 3 und und IN cord-015369-72cjogxz 1512 4 2007 2007 CD cord-015369-72cjogxz 1512 5 wurde wurde NN cord-015369-72cjogxz 1512 6 93 93 CD cord-015369-72cjogxz 1512 7 Patienten Patienten NNP cord-015369-72cjogxz 1512 8 an an DT cord-015369-72cjogxz 1512 9 unserer unserer JJ cord-015369-72cjogxz 1512 10 Institution Institution NNP cord-015369-72cjogxz 1512 11 wegen wegen NNP cord-015369-72cjogxz 1512 12 eines eines NNP cord-015369-72cjogxz 1512 13 ICC ICC NNP cord-015369-72cjogxz 1512 14 operiert operiert NN cord-015369-72cjogxz 1512 15 . . . cord-015369-72cjogxz 1513 1 Aus Aus NNP cord-015369-72cjogxz 1513 2 dieser dieser NNP cord-015369-72cjogxz 1513 3 Kohorte Kohorte NNP cord-015369-72cjogxz 1513 4 wurden wurden VBD cord-015369-72cjogxz 1513 5 46 46 CD cord-015369-72cjogxz 1514 1 Patienten Patienten NNP cord-015369-72cjogxz 1514 2 ermittelt ermittelt NNS cord-015369-72cjogxz 1514 3 , , , cord-015369-72cjogxz 1514 4 die die VBP cord-015369-72cjogxz 1514 5 mit mit NNP cord-015369-72cjogxz 1514 6 kurativer kurativer NNP cord-015369-72cjogxz 1514 7 Resektion Resektion NNP cord-015369-72cjogxz 1514 8 und und IN cord-015369-72cjogxz 1514 9 Lymphadenektomie Lymphadenektomie NNP cord-015369-72cjogxz 1514 10 behandelt behandelt NNP cord-015369-72cjogxz 1514 11 wurden wurden VBD cord-015369-72cjogxz 1514 12 . . . cord-015369-72cjogxz 1515 1 Aus Aus NNP cord-015369-72cjogxz 1515 2 diesem diesem NNP cord-015369-72cjogxz 1515 3 Kollektiv Kollektiv NNP cord-015369-72cjogxz 1515 4 wurde wurde NN cord-015369-72cjogxz 1516 1 eine eine NNP cord-015369-72cjogxz 1516 2 uni uni NNP cord-015369-72cjogxz 1516 3 - - HYPH cord-015369-72cjogxz 1516 4 und und NNP cord-015369-72cjogxz 1516 5 multivariate multivariate JJ cord-015369-72cjogxz 1516 6 Analyse Analyse NNP cord-015369-72cjogxz 1516 7 prognostischer prognostischer NN cord-015369-72cjogxz 1516 8 Faktoren Faktoren NNP cord-015369-72cjogxz 1516 9 für für IN cord-015369-72cjogxz 1516 10 Rezidiv Rezidiv NNP cord-015369-72cjogxz 1516 11 ( ( -LRB- cord-015369-72cjogxz 1516 12 RFS RFS NNP cord-015369-72cjogxz 1516 13 ) ) -RRB- cord-015369-72cjogxz 1516 14 und und NNP cord-015369-72cjogxz 1516 15 Ü Ü NNP cord-015369-72cjogxz 1516 16 berleben berleben NNP cord-015369-72cjogxz 1516 17 ( ( -LRB- cord-015369-72cjogxz 1516 18 OS OS NNP cord-015369-72cjogxz 1516 19 ) ) -RRB- cord-015369-72cjogxz 1516 20 durchgeführt durchgeführt NN cord-015369-72cjogxz 1516 21 . . . cord-015369-72cjogxz 1517 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1517 2 . . . cord-015369-72cjogxz 1518 1 Sowohl Sowohl NNP cord-015369-72cjogxz 1518 2 Tumorgröße Tumorgröße NNP cord-015369-72cjogxz 1518 3 als als NN cord-015369-72cjogxz 1518 4 auch auch NNP cord-015369-72cjogxz 1518 5 UICC UICC NNP cord-015369-72cjogxz 1518 6 Stadium Stadium NNP cord-015369-72cjogxz 1518 7 waren waren VBD cord-015369-72cjogxz 1518 8 sowohl sowohl NNP cord-015369-72cjogxz 1518 9 für für NNP cord-015369-72cjogxz 1518 10 Rezidiv Rezidiv NNP cord-015369-72cjogxz 1518 11 als als NN cord-015369-72cjogxz 1518 12 auch auch JJ cord-015369-72cjogxz 1518 13 Ü ü NN cord-015369-72cjogxz 1518 14 berleben berleben NN cord-015369-72cjogxz 1518 15 prognostisch prognostisch NNP cord-015369-72cjogxz 1518 16 . . . cord-015369-72cjogxz 1519 1 Ein Ein NNP cord-015369-72cjogxz 1519 2 erhöhter erhöhter NNP cord-015369-72cjogxz 1519 3 Quotient quotient NN cord-015369-72cjogxz 1519 4 von von NNP cord-015369-72cjogxz 1519 5 positiven positiven NNP cord-015369-72cjogxz 1519 6 zu zu NNP cord-015369-72cjogxz 1519 7 gesamt gesamt NNP cord-015369-72cjogxz 1520 1 entfernten entfernten NNP cord-015369-72cjogxz 1520 2 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 1520 3 ( ( -LRB- cord-015369-72cjogxz 1520 4 Lymph lymph NN cord-015369-72cjogxz 1520 5 node node NN cord-015369-72cjogxz 1520 6 ratio ratio NN cord-015369-72cjogxz 1520 7 , , , cord-015369-72cjogxz 1520 8 LNR LNR NNP cord-015369-72cjogxz 1520 9 ) ) -RRB- cord-015369-72cjogxz 1520 10 war war NN cord-015369-72cjogxz 1520 11 für für NN cord-015369-72cjogxz 1520 12 die die VBP cord-015369-72cjogxz 1520 13 Patientengruppe Patientengruppe NNP cord-015369-72cjogxz 1520 14 mit mit NNP cord-015369-72cjogxz 1520 15 positiven positiven JJ cord-015369-72cjogxz 1520 16 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 1520 17 prognostisch prognostisch NNP cord-015369-72cjogxz 1520 18 für für IN cord-015369-72cjogxz 1520 19 Rezidiv Rezidiv NNP cord-015369-72cjogxz 1520 20 und und IN cord-015369-72cjogxz 1520 21 Ü Ü NNP cord-015369-72cjogxz 1520 22 berleben berleben NN cord-015369-72cjogxz 1520 23 ( ( -LRB- cord-015369-72cjogxz 1520 24 HR HR NNP cord-015369-72cjogxz 1520 25 für für IN cord-015369-72cjogxz 1520 26 OS OS NNP cord-015369-72cjogxz 1520 27 ¼ ¼ NNP cord-015369-72cjogxz 1520 28 8.9 8.9 CD cord-015369-72cjogxz 1520 29 , , , cord-015369-72cjogxz 1520 30 95 95 CD cord-015369-72cjogxz 1520 31 % % NN cord-015369-72cjogxz 1520 32 CI CI NNP cord-015369-72cjogxz 1520 33 1.5 1.5 CD cord-015369-72cjogxz 1520 34 - - HYPH cord-015369-72cjogxz 1520 35 32.5 32.5 CD cord-015369-72cjogxz 1520 36 ; ; : cord-015369-72cjogxz 1520 37 HR HR NNP cord-015369-72cjogxz 1520 38 für für IN cord-015369-72cjogxz 1520 39 RFS RFS NNP cord-015369-72cjogxz 1520 40 ¼ ¼ NNP cord-015369-72cjogxz 1520 41 8.8 8.8 CD cord-015369-72cjogxz 1520 42 , , , cord-015369-72cjogxz 1520 43 95 95 CD cord-015369-72cjogxz 1520 44 % % NN cord-015369-72cjogxz 1520 45 CI ci NN cord-015369-72cjogxz 1521 1 2.0 2.0 CD cord-015369-72cjogxz 1521 2 - - SYM cord-015369-72cjogxz 1521 3 39.2 39.2 CD cord-015369-72cjogxz 1521 4 ) ) -RRB- cord-015369-72cjogxz 1521 5 . . . cord-015369-72cjogxz 1522 1 In in IN cord-015369-72cjogxz 1522 2 der der NNP cord-015369-72cjogxz 1522 3 multivariaten multivariaten NNP cord-015369-72cjogxz 1522 4 Analyse Analyse NNP cord-015369-72cjogxz 1522 5 bestätigte bestätigte NNP cord-015369-72cjogxz 1523 1 sich sich NNP cord-015369-72cjogxz 1523 2 LNR LNR NNP cord-015369-72cjogxz 1523 3 als als NN cord-015369-72cjogxz 1523 4 ebenso ebenso NNP cord-015369-72cjogxz 1524 1 starker stark JJR cord-015369-72cjogxz 1524 2 prognostischer prognostischer NNP cord-015369-72cjogxz 1524 3 Faktor Faktor NNP cord-015369-72cjogxz 1524 4 ( ( -LRB- cord-015369-72cjogxz 1524 5 adjusted adjust VBN cord-015369-72cjogxz 1524 6 HR HR NNP cord-015369-72cjogxz 1524 7 [ [ -LRB- cord-015369-72cjogxz 1524 8 LNR LNR NNP cord-015369-72cjogxz 1524 9 ] ] -RRB- cord-015369-72cjogxz 1524 10 für für JJ cord-015369-72cjogxz 1524 11 OS OS NNP cord-015369-72cjogxz 1524 12 ¼ ¼ NNP cord-015369-72cjogxz 1524 13 9.8 9.8 CD cord-015369-72cjogxz 1524 14 , , , cord-015369-72cjogxz 1524 15 95 95 CD cord-015369-72cjogxz 1524 16 % % NN cord-015369-72cjogxz 1524 17 CI CI NNP cord-015369-72cjogxz 1524 18 1.5 1.5 CD cord-015369-72cjogxz 1524 19 - - HYPH cord-015369-72cjogxz 1524 20 43.4 43.4 CD cord-015369-72cjogxz 1524 21 ; ; : cord-015369-72cjogxz 1524 22 HR HR NNP cord-015369-72cjogxz 1524 23 für für IN cord-015369-72cjogxz 1524 24 RFS RFS NNP cord-015369-72cjogxz 1524 25 ¼ ¼ CD cord-015369-72cjogxz 1525 1 8.3 8.3 CD cord-015369-72cjogxz 1525 2 , , , cord-015369-72cjogxz 1525 3 95 95 CD cord-015369-72cjogxz 1525 4 % % NN cord-015369-72cjogxz 1525 5 CI CI NNP cord-015369-72cjogxz 1525 6 1.7 1.7 CD cord-015369-72cjogxz 1525 7 - - SYM cord-015369-72cjogxz 1525 8 40.9 40.9 CD cord-015369-72cjogxz 1525 9 ) ) -RRB- cord-015369-72cjogxz 1525 10 . . . cord-015369-72cjogxz 1526 1 Die die VB cord-015369-72cjogxz 1526 2 Anzahl Anzahl NNP cord-015369-72cjogxz 1526 3 der der NNP cord-015369-72cjogxz 1526 4 entfernten entfernten NNP cord-015369-72cjogxz 1527 1 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 1527 2 hatte hatte NNP cord-015369-72cjogxz 1527 3 keinen keinen NNP cord-015369-72cjogxz 1528 1 Einfluss Einfluss NNP cord-015369-72cjogxz 1528 2 auf auf NNP cord-015369-72cjogxz 1528 3 Ü Ü NNP cord-015369-72cjogxz 1528 4 berleben berleben NN cord-015369-72cjogxz 1528 5 oder oder NNP cord-015369-72cjogxz 1528 6 Rezidiv Rezidiv NNP cord-015369-72cjogxz 1528 7 . . . cord-015369-72cjogxz 1529 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1529 2 . . . cord-015369-72cjogxz 1530 1 LNR LNR NNP cord-015369-72cjogxz 1530 2 ist ist NNP cord-015369-72cjogxz 1530 3 ein ein NNP cord-015369-72cjogxz 1530 4 neuer neuer NNP cord-015369-72cjogxz 1530 5 prognostischer prognostischer NNP cord-015369-72cjogxz 1530 6 Faktor Faktor NNP cord-015369-72cjogxz 1530 7 für für NNP cord-015369-72cjogxz 1530 8 Ü Ü NNP cord-015369-72cjogxz 1530 9 berleben berleben NN cord-015369-72cjogxz 1530 10 und und XX cord-015369-72cjogxz 1531 1 Rezidiv Rezidiv NNP cord-015369-72cjogxz 1531 2 nach nach NNP cord-015369-72cjogxz 1531 3 kurativer kurativer NNP cord-015369-72cjogxz 1531 4 Resektion Resektion NNP cord-015369-72cjogxz 1531 5 wegen wegen NNP cord-015369-72cjogxz 1531 6 ICC ICC NNP cord-015369-72cjogxz 1531 7 . . . cord-015369-72cjogxz 1532 1 Die die VB cord-015369-72cjogxz 1532 2 therapeutische therapeutische IN cord-015369-72cjogxz 1532 3 Relevanz Relevanz NNP cord-015369-72cjogxz 1532 4 dieser dieser NNP cord-015369-72cjogxz 1532 5 Beobachtung Beobachtung NNP cord-015369-72cjogxz 1532 6 sollte sollte NNP cord-015369-72cjogxz 1532 7 in in IN cord-015369-72cjogxz 1532 8 einer einer NNP cord-015369-72cjogxz 1532 9 prospektiven prospektiven NNP cord-015369-72cjogxz 1533 1 Untersuchung Untersuchung NNP cord-015369-72cjogxz 1533 2 geklärt geklärt NNP cord-015369-72cjogxz 1534 1 werden werden NNP cord-015369-72cjogxz 1534 2 . . . cord-015369-72cjogxz 1535 1 Background background NN cord-015369-72cjogxz 1535 2 . . . cord-015369-72cjogxz 1536 1 Patients patient NNS cord-015369-72cjogxz 1536 2 with with IN cord-015369-72cjogxz 1536 3 advanced advanced JJ cord-015369-72cjogxz 1536 4 cholangiocarcinoma cholangiocarcinoma NNS cord-015369-72cjogxz 1536 5 have have VBP cord-015369-72cjogxz 1536 6 a a DT cord-015369-72cjogxz 1536 7 poor poor JJ cord-015369-72cjogxz 1536 8 prognosis prognosis NN cord-015369-72cjogxz 1536 9 and and CC cord-015369-72cjogxz 1536 10 until until IN cord-015369-72cjogxz 1536 11 now now RB cord-015369-72cjogxz 1536 12 , , , cord-015369-72cjogxz 1536 13 no no DT cord-015369-72cjogxz 1536 14 standard standard JJ cord-015369-72cjogxz 1536 15 palliative palliative JJ cord-015369-72cjogxz 1536 16 chemotherapy chemotherapy NN cord-015369-72cjogxz 1536 17 has have VBZ cord-015369-72cjogxz 1536 18 been be VBN cord-015369-72cjogxz 1536 19 defined define VBN cord-015369-72cjogxz 1536 20 . . . cord-015369-72cjogxz 1537 1 The the DT cord-015369-72cjogxz 1537 2 purpose purpose NN cord-015369-72cjogxz 1537 3 of of IN cord-015369-72cjogxz 1537 4 this this DT cord-015369-72cjogxz 1537 5 prospective prospective JJ cord-015369-72cjogxz 1537 6 single single JJ cord-015369-72cjogxz 1537 7 - - HYPH cord-015369-72cjogxz 1537 8 centre centre NN cord-015369-72cjogxz 1537 9 phase phase NN cord-015369-72cjogxz 1537 10 II ii CD cord-015369-72cjogxz 1537 11 study study NN cord-015369-72cjogxz 1537 12 was be VBD cord-015369-72cjogxz 1537 13 to to TO cord-015369-72cjogxz 1537 14 investigate investigate VB cord-015369-72cjogxz 1537 15 the the DT cord-015369-72cjogxz 1537 16 therapeutic therapeutic JJ cord-015369-72cjogxz 1537 17 efficacy efficacy NN cord-015369-72cjogxz 1537 18 , , , cord-015369-72cjogxz 1537 19 safety safety NN cord-015369-72cjogxz 1537 20 and and CC cord-015369-72cjogxz 1537 21 K K NNP cord-015369-72cjogxz 1537 22 - - HYPH cord-015369-72cjogxz 1537 23 ras ras NN cord-015369-72cjogxz 1537 24 status status NN cord-015369-72cjogxz 1537 25 dependence dependence NN cord-015369-72cjogxz 1537 26 of of IN cord-015369-72cjogxz 1537 27 cetuximab cetuximab NNS cord-015369-72cjogxz 1537 28 in in IN cord-015369-72cjogxz 1537 29 combination combination NN cord-015369-72cjogxz 1537 30 with with IN cord-015369-72cjogxz 1537 31 GEMOX GEMOX NNP cord-015369-72cjogxz 1537 32 in in IN cord-015369-72cjogxz 1537 33 the the DT cord-015369-72cjogxz 1537 34 palliative palliative JJ cord-015369-72cjogxz 1537 35 first first JJ cord-015369-72cjogxz 1537 36 line line NN cord-015369-72cjogxz 1537 37 treatment treatment NN cord-015369-72cjogxz 1537 38 of of IN cord-015369-72cjogxz 1537 39 these these DT cord-015369-72cjogxz 1537 40 patients patient NNS cord-015369-72cjogxz 1537 41 . . . cord-015369-72cjogxz 1538 1 Methods method NNS cord-015369-72cjogxz 1538 2 . . . cord-015369-72cjogxz 1539 1 Patients patient NNS cord-015369-72cjogxz 1539 2 with with IN cord-015369-72cjogxz 1539 3 locally locally RB cord-015369-72cjogxz 1539 4 advanced advanced JJ cord-015369-72cjogxz 1539 5 , , , cord-015369-72cjogxz 1539 6 metastatic metastatic JJ cord-015369-72cjogxz 1539 7 cholangiocarcinoma cholangiocarcinoma NNS cord-015369-72cjogxz 1539 8 or or CC cord-015369-72cjogxz 1539 9 gallbladder gallbladder NN cord-015369-72cjogxz 1539 10 cancer cancer NN cord-015369-72cjogxz 1539 11 were be VBD cord-015369-72cjogxz 1539 12 treated treat VBN cord-015369-72cjogxz 1539 13 with with IN cord-015369-72cjogxz 1539 14 Cetuximab Cetuximab NNP cord-015369-72cjogxz 1539 15 500 500 CD cord-015369-72cjogxz 1539 16 mg mg NNP cord-015369-72cjogxz 1539 17 / / SYM cord-015369-72cjogxz 1539 18 m m NN cord-015369-72cjogxz 1539 19 2 2 CD cord-015369-72cjogxz 1539 20 followed follow VBN cord-015369-72cjogxz 1539 21 by by IN cord-015369-72cjogxz 1539 22 1000 1000 CD cord-015369-72cjogxz 1539 23 mg mg NNP cord-015369-72cjogxz 1539 24 / / SYM cord-015369-72cjogxz 1539 25 m m NN cord-015369-72cjogxz 1539 26 2 2 CD cord-015369-72cjogxz 1539 27 Gemcitabine Gemcitabine NNP cord-015369-72cjogxz 1539 28 ( ( -LRB- cord-015369-72cjogxz 1539 29 day day NN cord-015369-72cjogxz 1539 30 1 1 CD cord-015369-72cjogxz 1539 31 ) ) -RRB- cord-015369-72cjogxz 1539 32 and and CC cord-015369-72cjogxz 1539 33 100 100 CD cord-015369-72cjogxz 1539 34 mg mg NNP cord-015369-72cjogxz 1539 35 / / SYM cord-015369-72cjogxz 1539 36 m m NNP cord-015369-72cjogxz 1539 37 2 2 CD cord-015369-72cjogxz 1539 38 Oxaliplatin Oxaliplatin NNP cord-015369-72cjogxz 1539 39 ( ( -LRB- cord-015369-72cjogxz 1539 40 day day NN cord-015369-72cjogxz 1539 41 2 2 CD cord-015369-72cjogxz 1539 42 ) ) -RRB- cord-015369-72cjogxz 1539 43 every every DT cord-015369-72cjogxz 1539 44 second second JJ cord-015369-72cjogxz 1539 45 week week NN cord-015369-72cjogxz 1539 46 . . . cord-015369-72cjogxz 1540 1 Results result NNS cord-015369-72cjogxz 1540 2 . . . cord-015369-72cjogxz 1541 1 From from IN cord-015369-72cjogxz 1541 2 October October NNP cord-015369-72cjogxz 1541 3 2006 2006 CD cord-015369-72cjogxz 1541 4 until until IN cord-015369-72cjogxz 1541 5 July July NNP cord-015369-72cjogxz 1541 6 2008 2008 CD cord-015369-72cjogxz 1541 7 thirty thirty CD cord-015369-72cjogxz 1541 8 patients patient NNS cord-015369-72cjogxz 1541 9 ( ( -LRB- cord-015369-72cjogxz 1541 10 15 15 CD cord-015369-72cjogxz 1541 11 male male NN cord-015369-72cjogxz 1541 12 , , , cord-015369-72cjogxz 1541 13 15 15 CD cord-015369-72cjogxz 1541 14 female female NN cord-015369-72cjogxz 1541 15 ) ) -RRB- cord-015369-72cjogxz 1541 16 with with IN cord-015369-72cjogxz 1541 17 a a DT cord-015369-72cjogxz 1541 18 median median JJ cord-015369-72cjogxz 1541 19 age age NN cord-015369-72cjogxz 1541 20 of of IN cord-015369-72cjogxz 1541 21 68 68 CD cord-015369-72cjogxz 1541 22 were be VBD cord-015369-72cjogxz 1541 23 enrolled enrol VBN cord-015369-72cjogxz 1541 24 . . . cord-015369-72cjogxz 1542 1 The the DT cord-015369-72cjogxz 1542 2 overall overall JJ cord-015369-72cjogxz 1542 3 response response NN cord-015369-72cjogxz 1542 4 rate rate NN cord-015369-72cjogxz 1542 5 of of IN cord-015369-72cjogxz 1542 6 evaluable evaluable JJ cord-015369-72cjogxz 1542 7 patients patient NNS cord-015369-72cjogxz 1542 8 ( ( -LRB- cord-015369-72cjogxz 1542 9 30 30 CD cord-015369-72cjogxz 1542 10 ) ) -RRB- cord-015369-72cjogxz 1542 11 was be VBD cord-015369-72cjogxz 1542 12 63,3 63,3 CD cord-015369-72cjogxz 1542 13 % % NN cord-015369-72cjogxz 1542 14 , , , cord-015369-72cjogxz 1542 15 including include VBG cord-015369-72cjogxz 1542 16 three three CD cord-015369-72cjogxz 1542 17 patient patient NN cord-015369-72cjogxz 1542 18 with with IN cord-015369-72cjogxz 1542 19 a a DT cord-015369-72cjogxz 1542 20 complete complete JJ cord-015369-72cjogxz 1542 21 radiological radiological JJ cord-015369-72cjogxz 1542 22 response response NN cord-015369-72cjogxz 1542 23 . . . cord-015369-72cjogxz 1543 1 5 5 CD cord-015369-72cjogxz 1543 2 patients patient NNS cord-015369-72cjogxz 1543 3 ( ( -LRB- cord-015369-72cjogxz 1543 4 16.7 16.7 CD cord-015369-72cjogxz 1543 5 % % NN cord-015369-72cjogxz 1543 6 ) ) -RRB- cord-015369-72cjogxz 1543 7 achieved achieve VBN cord-015369-72cjogxz 1543 8 stable stable JJ cord-015369-72cjogxz 1543 9 disease disease NN cord-015369-72cjogxz 1543 10 and and CC cord-015369-72cjogxz 1543 11 only only RB cord-015369-72cjogxz 1543 12 6 6 CD cord-015369-72cjogxz 1543 13 patients patient NNS cord-015369-72cjogxz 1543 14 ( ( -LRB- cord-015369-72cjogxz 1543 15 20 20 CD cord-015369-72cjogxz 1543 16 % % NN cord-015369-72cjogxz 1543 17 ) ) -RRB- cord-015369-72cjogxz 1543 18 progressed progress VBD cord-015369-72cjogxz 1543 19 under under IN cord-015369-72cjogxz 1543 20 chemotherapy chemotherapy NN cord-015369-72cjogxz 1543 21 . . . cord-015369-72cjogxz 1544 1 Nine nine CD cord-015369-72cjogxz 1544 2 initially initially RB cord-015369-72cjogxz 1544 3 unresectable unresectable JJ cord-015369-72cjogxz 1544 4 patients patient NNS cord-015369-72cjogxz 1544 5 underwent undergo VBD cord-015369-72cjogxz 1544 6 a a DT cord-015369-72cjogxz 1544 7 curative curative JJ cord-015369-72cjogxz 1544 8 resection resection NN cord-015369-72cjogxz 1544 9 after after IN cord-015369-72cjogxz 1544 10 major major JJ cord-015369-72cjogxz 1544 11 response response NN cord-015369-72cjogxz 1544 12 was be VBD cord-015369-72cjogxz 1544 13 observed observe VBN cord-015369-72cjogxz 1544 14 ( ( -LRB- cord-015369-72cjogxz 1544 15 30 30 CD cord-015369-72cjogxz 1544 16 % % NN cord-015369-72cjogxz 1544 17 ) ) -RRB- cord-015369-72cjogxz 1544 18 . . . cord-015369-72cjogxz 1545 1 Five five CD cord-015369-72cjogxz 1545 2 patients patient NNS cord-015369-72cjogxz 1545 3 are be VBP cord-015369-72cjogxz 1545 4 currently currently RB cord-015369-72cjogxz 1545 5 without without IN cord-015369-72cjogxz 1545 6 evidence evidence NN cord-015369-72cjogxz 1545 7 of of IN cord-015369-72cjogxz 1545 8 disease disease NN cord-015369-72cjogxz 1545 9 after after IN cord-015369-72cjogxz 1545 10 a a DT cord-015369-72cjogxz 1545 11 median median JJ cord-015369-72cjogxz 1545 12 follow follow NN cord-015369-72cjogxz 1545 13 - - HYPH cord-015369-72cjogxz 1545 14 up up NN cord-015369-72cjogxz 1545 15 of of IN cord-015369-72cjogxz 1545 16 16,3 16,3 CD cord-015369-72cjogxz 1545 17 months month NNS cord-015369-72cjogxz 1545 18 post post VBP cord-015369-72cjogxz 1545 19 curative curative JJ cord-015369-72cjogxz 1545 20 liver liver NN cord-015369-72cjogxz 1545 21 resection resection NN cord-015369-72cjogxz 1545 22 . . . cord-015369-72cjogxz 1546 1 K K NNP cord-015369-72cjogxz 1546 2 - - HYPH cord-015369-72cjogxz 1546 3 ras ras NNP cord-015369-72cjogxz 1546 4 mutation mutation NN cord-015369-72cjogxz 1546 5 was be VBD cord-015369-72cjogxz 1546 6 detected detect VBN cord-015369-72cjogxz 1546 7 in in IN cord-015369-72cjogxz 1546 8 3 3 CD cord-015369-72cjogxz 1546 9 patients patient NNS cord-015369-72cjogxz 1546 10 ( ( -LRB- cord-015369-72cjogxz 1546 11 12 12 CD cord-015369-72cjogxz 1546 12 % % NN cord-015369-72cjogxz 1546 13 ) ) -RRB- cord-015369-72cjogxz 1546 14 . . . cord-015369-72cjogxz 1547 1 All all DT cord-015369-72cjogxz 1547 2 three three CD cord-015369-72cjogxz 1547 3 patients patient NNS cord-015369-72cjogxz 1547 4 did do VBD cord-015369-72cjogxz 1547 5 not not RB cord-015369-72cjogxz 1547 6 progress progress VB cord-015369-72cjogxz 1547 7 under under IN cord-015369-72cjogxz 1547 8 chemotherapy chemotherapy NN cord-015369-72cjogxz 1547 9 . . . cord-015369-72cjogxz 1548 1 Neither neither CC cord-015369-72cjogxz 1548 2 PFS PFS NNP cord-015369-72cjogxz 1548 3 nor nor CC cord-015369-72cjogxz 1548 4 OS OS NNP cord-015369-72cjogxz 1548 5 were be VBD cord-015369-72cjogxz 1548 6 affected affect VBN cord-015369-72cjogxz 1548 7 by by IN cord-015369-72cjogxz 1548 8 K K NNP cord-015369-72cjogxz 1548 9 - - HYPH cord-015369-72cjogxz 1548 10 ras ras NNP cord-015369-72cjogxz 1548 11 status status NN cord-015369-72cjogxz 1548 12 . . . cord-015369-72cjogxz 1549 1 The the DT cord-015369-72cjogxz 1549 2 median median JJ cord-015369-72cjogxz 1549 3 PFS PFS NNP cord-015369-72cjogxz 1549 4 of of IN cord-015369-72cjogxz 1549 5 all all DT cord-015369-72cjogxz 1549 6 30 30 CD cord-015369-72cjogxz 1549 7 patients patient NNS cord-015369-72cjogxz 1549 8 was be VBD cord-015369-72cjogxz 1549 9 8.3 8.3 CD cord-015369-72cjogxz 1549 10 months month NNS cord-015369-72cjogxz 1549 11 and and CC cord-015369-72cjogxz 1549 12 median median JJ cord-015369-72cjogxz 1549 13 OS OS NNP cord-015369-72cjogxz 1549 14 was be VBD cord-015369-72cjogxz 1549 15 12.7 12.7 CD cord-015369-72cjogxz 1549 16 months month NNS cord-015369-72cjogxz 1549 17 . . . cord-015369-72cjogxz 1550 1 Conclusions conclusion NNS cord-015369-72cjogxz 1550 2 . . . cord-015369-72cjogxz 1551 1 Cetuximab Cetuximab NNP cord-015369-72cjogxz 1551 2 in in IN cord-015369-72cjogxz 1551 3 combination combination NN cord-015369-72cjogxz 1551 4 with with IN cord-015369-72cjogxz 1551 5 GemOx GemOx NNP cord-015369-72cjogxz 1551 6 induces induce VBZ cord-015369-72cjogxz 1551 7 impressive impressive JJ cord-015369-72cjogxz 1551 8 response response NN cord-015369-72cjogxz 1551 9 rates rate NNS cord-015369-72cjogxz 1551 10 which which WDT cord-015369-72cjogxz 1551 11 were be VBD cord-015369-72cjogxz 1551 12 unrelated unrelated JJ cord-015369-72cjogxz 1551 13 to to IN cord-015369-72cjogxz 1551 14 kras kras NNP cord-015369-72cjogxz 1551 15 status status NN cord-015369-72cjogxz 1551 16 . . . cord-015369-72cjogxz 1552 1 PFS PFS NNP cord-015369-72cjogxz 1552 2 and and CC cord-015369-72cjogxz 1552 3 OS OS NNP cord-015369-72cjogxz 1552 4 were be VBD cord-015369-72cjogxz 1552 5 remarkably remarkably RB cord-015369-72cjogxz 1552 6 improved improved JJ cord-015369-72cjogxz 1552 7 and and CC cord-015369-72cjogxz 1552 8 therefore therefore RB cord-015369-72cjogxz 1552 9 cetuximab cetuximab VBD cord-015369-72cjogxz 1552 10 in in IN cord-015369-72cjogxz 1552 11 combination combination NN cord-015369-72cjogxz 1552 12 with with IN cord-015369-72cjogxz 1552 13 GEMOX GEMOX NNP cord-015369-72cjogxz 1552 14 deserves deserve VBZ cord-015369-72cjogxz 1552 15 further further JJ cord-015369-72cjogxz 1552 16 evaluation evaluation NN cord-015369-72cjogxz 1552 17 in in IN cord-015369-72cjogxz 1552 18 prospective prospective JJ cord-015369-72cjogxz 1552 19 randomized randomized JJ cord-015369-72cjogxz 1552 20 trials trial NNS cord-015369-72cjogxz 1552 21 . . . cord-015369-72cjogxz 1553 1 Methodik Methodik NNP cord-015369-72cjogxz 1553 2 . . . cord-015369-72cjogxz 1554 1 Es Es NNP cord-015369-72cjogxz 1554 2 wurde wurde VBD cord-015369-72cjogxz 1554 3 eine eine NNP cord-015369-72cjogxz 1554 4 retrospektive retrospektive NNP cord-015369-72cjogxz 1555 1 Analyse analyse VB cord-015369-72cjogxz 1555 2 anhand anhand NNP cord-015369-72cjogxz 1556 1 einer einer NNP cord-015369-72cjogxz 1556 2 pro pro JJ cord-015369-72cjogxz 1556 3 - - JJ cord-015369-72cjogxz 1556 4 spektiv spektiv JJ cord-015369-72cjogxz 1556 5 geführten geführten NNP cord-015369-72cjogxz 1556 6 Datenbank Datenbank NNP cord-015369-72cjogxz 1556 7 an an DT cord-015369-72cjogxz 1556 8 der der NNP cord-015369-72cjogxz 1556 9 Abteilung Abteilung NNP cord-015369-72cjogxz 1556 10 für für IN cord-015369-72cjogxz 1556 11 Unfallchirurgie Unfallchirurgie NNP cord-015369-72cjogxz 1556 12 durchgeführt durchgeführt NN cord-015369-72cjogxz 1557 1 und und IN cord-015369-72cjogxz 1557 2 jene jene NNP cord-015369-72cjogxz 1557 3 Patienten Patienten NNP cord-015369-72cjogxz 1557 4 ermittelt ermittelt NNP cord-015369-72cjogxz 1557 5 , , , cord-015369-72cjogxz 1557 6 die die VBP cord-015369-72cjogxz 1557 7 i -PRON- PRP cord-015369-72cjogxz 1557 8 m be VBP cord-015369-72cjogxz 1557 9 Anschluss Anschluss NNP cord-015369-72cjogxz 1558 1 an an DT cord-015369-72cjogxz 1558 2 ein ein NN cord-015369-72cjogxz 1558 3 ausgedehntes ausgedehnte NNS cord-015369-72cjogxz 1559 1 Trauma trauma NN cord-015369-72cjogxz 1560 1 i -PRON- PRP cord-015369-72cjogxz 1560 2 m be VBP cord-015369-72cjogxz 1560 3 Bereich Bereich NNP cord-015369-72cjogxz 1560 4 der der NNP cord-015369-72cjogxz 1560 5 oberen oberen NNP cord-015369-72cjogxz 1561 1 Extremität Extremität NNP cord-015369-72cjogxz 1561 2 neben neben NNP cord-015369-72cjogxz 1561 3 einer einer NNP cord-015369-72cjogxz 1561 4 knöchernen knöchernen NNP cord-015369-72cjogxz 1561 5 Versor Versor NNP cord-015369-72cjogxz 1561 6 - - HYPH cord-015369-72cjogxz 1561 7 gung gung NNP cord-015369-72cjogxz 1561 8 mit mit NNP cord-015369-72cjogxz 1561 9 einer einer NNP cord-015369-72cjogxz 1561 10 freien freien NNP cord-015369-72cjogxz 1561 11 Lappenplastik Lappenplastik NNP cord-015369-72cjogxz 1561 12 versorgt versorgt NN cord-015369-72cjogxz 1561 13 wurden wurden NNP cord-015369-72cjogxz 1561 14 . . . cord-015369-72cjogxz 1562 1 Der Der NNP cord-015369-72cjogxz 1562 2 erfasste erfasste NN cord-015369-72cjogxz 1562 3 Zeitraum Zeitraum NNP cord-015369-72cjogxz 1562 4 lag lag HYPH cord-015369-72cjogxz 1562 5 zwischen zwischen NNP cord-015369-72cjogxz 1562 6 1 1 CD cord-015369-72cjogxz 1562 7 . . . cord-015369-72cjogxz 1563 1 Jänner Jänner NNP cord-015369-72cjogxz 1563 2 2008 2008 CD cord-015369-72cjogxz 1563 3 und und IN cord-015369-72cjogxz 1563 4 14 14 CD cord-015369-72cjogxz 1563 5 . . . cord-015369-72cjogxz 1564 1 Jänner Jänner NNP cord-015369-72cjogxz 1564 2 2009 2009 CD cord-015369-72cjogxz 1564 3 . . . cord-015369-72cjogxz 1565 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1565 2 . . . cord-015369-72cjogxz 1566 1 Die die VB cord-015369-72cjogxz 1566 2 Auswertung Auswertung NNP cord-015369-72cjogxz 1566 3 der der NNP cord-015369-72cjogxz 1566 4 Datenbank Datenbank NNP cord-015369-72cjogxz 1566 5 ergab ergab NNP cord-015369-72cjogxz 1566 6 10 10 CD cord-015369-72cjogxz 1566 7 Patienten Patienten NNP cord-015369-72cjogxz 1566 8 ( ( -LRB- cord-015369-72cjogxz 1566 9 3 3 CD cord-015369-72cjogxz 1566 10 weiblich weiblich NNP cord-015369-72cjogxz 1566 11 ) ) -RRB- cord-015369-72cjogxz 1566 12 , , , cord-015369-72cjogxz 1566 13 bei bei NNP cord-015369-72cjogxz 1566 14 de de NNP cord-015369-72cjogxz 1566 15 - - HYPH cord-015369-72cjogxz 1566 16 nen nen NNP cord-015369-72cjogxz 1566 17 eine eine FW cord-015369-72cjogxz 1566 18 solche solche NNP cord-015369-72cjogxz 1566 19 freie freie NNP cord-015369-72cjogxz 1566 20 Lappenplastik Lappenplastik NNP cord-015369-72cjogxz 1566 21 durchgeführt durchgeführt NN cord-015369-72cjogxz 1566 22 wurde wurde NNP cord-015369-72cjogxz 1566 23 . . . cord-015369-72cjogxz 1567 1 Jede Jede NNP cord-015369-72cjogxz 1567 2 Operation Operation NNP cord-015369-72cjogxz 1567 3 wurde wurde NN cord-015369-72cjogxz 1567 4 gemeinsam gemeinsam NNP cord-015369-72cjogxz 1567 5 mit mit NNP cord-015369-72cjogxz 1567 6 einem einem NNP cord-015369-72cjogxz 1567 7 Kollegen Kollegen NNP cord-015369-72cjogxz 1567 8 der der NNP cord-015369-72cjogxz 1567 9 Plastischen Plastischen NNP cord-015369-72cjogxz 1567 10 Chirurgie Chirurgie NNP cord-015369-72cjogxz 1567 11 und und XX cord-015369-72cjogxz 1567 12 der der NNP cord-015369-72cjogxz 1567 13 Unfallchirurgie Unfallchirurgie NNP cord-015369-72cjogxz 1567 14 durchgeführt durchgeführt NN cord-015369-72cjogxz 1567 15 . . . cord-015369-72cjogxz 1568 1 In in IN cord-015369-72cjogxz 1568 2 2 2 CD cord-015369-72cjogxz 1568 3 Fällen Fällen NNP cord-015369-72cjogxz 1568 4 kam kam NNP cord-015369-72cjogxz 1568 5 es es XX cord-015369-72cjogxz 1568 6 zu zu NNP cord-015369-72cjogxz 1568 7 einem einem NNP cord-015369-72cjogxz 1568 8 Lappenverlust Lappenverlust NNP cord-015369-72cjogxz 1568 9 , , , cord-015369-72cjogxz 1568 10 wobei wobei JJ cord-015369-72cjogxz 1568 11 daraus daraus NN cord-015369-72cjogxz 1568 12 in in IN cord-015369-72cjogxz 1568 13 einem einem NNP cord-015369-72cjogxz 1568 14 Fall Fall NNP cord-015369-72cjogxz 1568 15 ein ein NNP cord-015369-72cjogxz 1568 16 zweiter zweiter NNP cord-015369-72cjogxz 1568 17 erfolgreicher erfolgreicher NNP cord-015369-72cjogxz 1568 18 freier freier NNP cord-015369-72cjogxz 1568 19 Lappen Lappen NNP cord-015369-72cjogxz 1568 20 resultierte resultierte NNS cord-015369-72cjogxz 1568 21 und und IN cord-015369-72cjogxz 1568 22 in in IN cord-015369-72cjogxz 1568 23 dem dem NNP cord-015369-72cjogxz 1568 24 anderen anderen NNP cord-015369-72cjogxz 1568 25 Fall Fall NNP cord-015369-72cjogxz 1569 1 eine eine NNP cord-015369-72cjogxz 1569 2 Amputation Amputation NNP cord-015369-72cjogxz 1569 3 des des FW cord-015369-72cjogxz 1569 4 betroffenen betroffenen JJ cord-015369-72cjogxz 1569 5 Daumens Daumens NNP cord-015369-72cjogxz 1569 6 . . . cord-015369-72cjogxz 1570 1 I -PRON- PRP cord-015369-72cjogxz 1570 2 m be VBP cord-015369-72cjogxz 1571 1 Rest rest NN cord-015369-72cjogxz 1571 2 der der NNP cord-015369-72cjogxz 1571 3 Patienten Patienten NNP cord-015369-72cjogxz 1571 4 wurde wurde NN cord-015369-72cjogxz 1571 5 mit mit NNP cord-015369-72cjogxz 1571 6 der der NNP cord-015369-72cjogxz 1571 7 initialen initialen NNP cord-015369-72cjogxz 1571 8 Operation Operation NNP cord-015369-72cjogxz 1571 9 das das NNP cord-015369-72cjogxz 1571 10 operative operative NN cord-015369-72cjogxz 1571 11 Ziel Ziel NNP cord-015369-72cjogxz 1571 12 erreicht erreicht NNP cord-015369-72cjogxz 1571 13 . . . cord-015369-72cjogxz 1572 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1572 2 . . . cord-015369-72cjogxz 1573 1 Die die VB cord-015369-72cjogxz 1573 2 Implementierung Implementierung NNP cord-015369-72cjogxz 1573 3 mikrochirurgisch mikrochirurgisch JJ cord-015369-72cjogxz 1573 4 - - HYPH cord-015369-72cjogxz 1573 5 rekonstruktiver rekonstruktiver NNP cord-015369-72cjogxz 1573 6 Verfahren Verfahren NNP cord-015369-72cjogxz 1574 1 an an DT cord-015369-72cjogxz 1574 2 einer einer JJ cord-015369-72cjogxz 1574 3 großen großen JJ cord-015369-72cjogxz 1574 4 unfallchirurgischen unfallchirurgischen NNP cord-015369-72cjogxz 1575 1 Abteilung Abteilung NNP cord-015369-72cjogxz 1575 2 führte führte NNP cord-015369-72cjogxz 1576 1 zu zu NNP cord-015369-72cjogxz 1576 2 einer einer NNP cord-015369-72cjogxz 1576 3 deutlichen deutlichen NNP cord-015369-72cjogxz 1576 4 Steigerung Steigerung NNP cord-015369-72cjogxz 1576 5 in in IN cord-015369-72cjogxz 1576 6 der der NNP cord-015369-72cjogxz 1576 7 Versorgungsqualität Versorgungsqualität NNP cord-015369-72cjogxz 1576 8 bei bei NNP cord-015369-72cjogxz 1576 9 Patienten Patienten NNP cord-015369-72cjogxz 1576 10 mit mit NN cord-015369-72cjogxz 1576 11 komplexem komplexem NNP cord-015369-72cjogxz 1576 12 Trauma trauma NN cord-015369-72cjogxz 1577 1 i -PRON- PRP cord-015369-72cjogxz 1577 2 m be VBP cord-015369-72cjogxz 1577 3 Bereich Bereich NNP cord-015369-72cjogxz 1577 4 der der NNP cord-015369-72cjogxz 1577 5 oberen oberen NNP cord-015369-72cjogxz 1577 6 Extremität Extremität NNP cord-015369-72cjogxz 1577 7 . . . cord-015369-72cjogxz 1578 1 Trotz Trotz NNP cord-015369-72cjogxz 1578 2 eines eines NNP cord-015369-72cjogxz 1578 3 mitunter mitunter NNP cord-015369-72cjogxz 1578 4 sehr sehr NNP cord-015369-72cjogxz 1578 5 aufwändigen aufwändigen NNP cord-015369-72cjogxz 1578 6 operativen operativen NNP cord-015369-72cjogxz 1578 7 Verfahrens Verfahrens NNP cord-015369-72cjogxz 1578 8 konnte konnte NNP cord-015369-72cjogxz 1578 9 die die VB cord-015369-72cjogxz 1578 10 Zeit Zeit NNP cord-015369-72cjogxz 1578 11 bis bis JJ cord-015369-72cjogxz 1578 12 zur zur NNP cord-015369-72cjogxz 1578 13 kompletten kompletten NNP cord-015369-72cjogxz 1578 14 Abheilung Abheilung NNP cord-015369-72cjogxz 1578 15 deutlich deutlich NNP cord-015369-72cjogxz 1578 16 verkürzt verkürzt NNP cord-015369-72cjogxz 1578 17 werden werden NNP cord-015369-72cjogxz 1578 18 . . . cord-015369-72cjogxz 1579 1 facial facial JJ cord-015369-72cjogxz 1579 2 edema edema NN cord-015369-72cjogxz 1579 3 and and CC cord-015369-72cjogxz 1579 4 petechiae petechia NNS cord-015369-72cjogxz 1579 5 , , , cord-015369-72cjogxz 1579 6 subconjunctival subconjunctival JJ cord-015369-72cjogxz 1579 7 hemorrhage hemorrhage NN cord-015369-72cjogxz 1579 8 , , , cord-015369-72cjogxz 1579 9 and and CC cord-015369-72cjogxz 1579 10 occasionally occasionally RB cord-015369-72cjogxz 1579 11 neurological neurological JJ cord-015369-72cjogxz 1579 12 symptoms symptom NNS cord-015369-72cjogxz 1579 13 . . . cord-015369-72cjogxz 1580 1 Case case NN cord-015369-72cjogxz 1580 2 report report NN cord-015369-72cjogxz 1580 3 . . . cord-015369-72cjogxz 1581 1 A a DT cord-015369-72cjogxz 1581 2 46-year 46-year JJ cord-015369-72cjogxz 1581 3 - - HYPH cord-015369-72cjogxz 1581 4 old old JJ cord-015369-72cjogxz 1581 5 men man NNS cord-015369-72cjogxz 1581 6 was be VBD cord-015369-72cjogxz 1581 7 admitted admit VBN cord-015369-72cjogxz 1581 8 to to IN cord-015369-72cjogxz 1581 9 the the DT cord-015369-72cjogxz 1581 10 emergency emergency NN cord-015369-72cjogxz 1581 11 department department NN cord-015369-72cjogxz 1581 12 after after IN cord-015369-72cjogxz 1581 13 the the DT cord-015369-72cjogxz 1581 14 heavy heavy JJ cord-015369-72cjogxz 1581 15 metal metal NN cord-015369-72cjogxz 1581 16 door door NN cord-015369-72cjogxz 1581 17 had have VBD cord-015369-72cjogxz 1581 18 fallen fall VBN cord-015369-72cjogxz 1581 19 on on IN cord-015369-72cjogxz 1581 20 his -PRON- PRP$ cord-015369-72cjogxz 1581 21 chest chest NN cord-015369-72cjogxz 1581 22 . . . cord-015369-72cjogxz 1582 1 His -PRON- PRP$ cord-015369-72cjogxz 1582 2 head head NN cord-015369-72cjogxz 1582 3 , , , cord-015369-72cjogxz 1582 4 neck neck NN cord-015369-72cjogxz 1582 5 and and CC cord-015369-72cjogxz 1582 6 upper upper JJ cord-015369-72cjogxz 1582 7 chest chest NN cord-015369-72cjogxz 1582 8 were be VBD cord-015369-72cjogxz 1582 9 cyanotic cyanotic JJ cord-015369-72cjogxz 1582 10 and and CC cord-015369-72cjogxz 1582 11 edematous edematous JJ cord-015369-72cjogxz 1582 12 with with IN cord-015369-72cjogxz 1582 13 subconjunctival subconjunctival JJ cord-015369-72cjogxz 1582 14 hemorrhages hemorrhage NNS cord-015369-72cjogxz 1582 15 . . . cord-015369-72cjogxz 1583 1 Computer computer NN cord-015369-72cjogxz 1583 2 tomography tomography NN cord-015369-72cjogxz 1583 3 of of IN cord-015369-72cjogxz 1583 4 the the DT cord-015369-72cjogxz 1583 5 thorax thorax NN cord-015369-72cjogxz 1583 6 revealed reveal VBD cord-015369-72cjogxz 1583 7 multiple multiple JJ cord-015369-72cjogxz 1583 8 fractures fracture NNS cord-015369-72cjogxz 1583 9 of of IN cord-015369-72cjogxz 1583 10 the the DT cord-015369-72cjogxz 1583 11 ribs rib NNS cord-015369-72cjogxz 1583 12 on on IN cord-015369-72cjogxz 1583 13 the the DT cord-015369-72cjogxz 1583 14 left left JJ cord-015369-72cjogxz 1583 15 side side NN cord-015369-72cjogxz 1583 16 and and CC cord-015369-72cjogxz 1583 17 signs sign NNS cord-015369-72cjogxz 1583 18 for for IN cord-015369-72cjogxz 1583 19 pulmonary pulmonary JJ cord-015369-72cjogxz 1583 20 contusion contusion NN cord-015369-72cjogxz 1583 21 . . . cord-015369-72cjogxz 1584 1 On on IN cord-015369-72cjogxz 1584 2 the the DT cord-015369-72cjogxz 1584 3 eight eight CD cord-015369-72cjogxz 1584 4 day day NN cord-015369-72cjogxz 1584 5 the the DT cord-015369-72cjogxz 1584 6 facial facial JJ cord-015369-72cjogxz 1584 7 cyanosis cyanosis NN cord-015369-72cjogxz 1584 8 and and CC cord-015369-72cjogxz 1584 9 petechiae petechia NNS cord-015369-72cjogxz 1584 10 almost almost RB cord-015369-72cjogxz 1584 11 disappeared disappear VBD cord-015369-72cjogxz 1584 12 , , , cord-015369-72cjogxz 1584 13 only only RB cord-015369-72cjogxz 1584 14 subconjunctival subconjunctival JJ cord-015369-72cjogxz 1584 15 hemorrhage hemorrhage NN cord-015369-72cjogxz 1584 16 persisted persist VBD cord-015369-72cjogxz 1584 17 . . . cord-015369-72cjogxz 1585 1 Discussion discussion NN cord-015369-72cjogxz 1585 2 . . . cord-015369-72cjogxz 1586 1 The the DT cord-015369-72cjogxz 1586 2 symptoms symptom NNS cord-015369-72cjogxz 1586 3 are be VBP cord-015369-72cjogxz 1586 4 attributed attribute VBN cord-015369-72cjogxz 1586 5 to to IN cord-015369-72cjogxz 1586 6 thoracoabdominal thoracoabdominal JJ cord-015369-72cjogxz 1586 7 compression compression NN cord-015369-72cjogxz 1586 8 or or CC cord-015369-72cjogxz 1586 9 to to IN cord-015369-72cjogxz 1586 10 forceful forceful JJ cord-015369-72cjogxz 1586 11 compression compression NN cord-015369-72cjogxz 1586 12 of of IN cord-015369-72cjogxz 1586 13 the the DT cord-015369-72cjogxz 1586 14 thoracoabdominal thoracoabdominal JJ cord-015369-72cjogxz 1586 15 muscles muscle NNS cord-015369-72cjogxz 1586 16 against against IN cord-015369-72cjogxz 1586 17 a a DT cord-015369-72cjogxz 1586 18 closed closed JJ cord-015369-72cjogxz 1586 19 glottis glottis NN cord-015369-72cjogxz 1586 20 . . . cord-015369-72cjogxz 1587 1 A a DT cord-015369-72cjogxz 1587 2 reflux reflux NN cord-015369-72cjogxz 1587 3 of of IN cord-015369-72cjogxz 1587 4 blood blood NN cord-015369-72cjogxz 1587 5 from from IN cord-015369-72cjogxz 1587 6 the the DT cord-015369-72cjogxz 1587 7 heart heart NN cord-015369-72cjogxz 1587 8 through through IN cord-015369-72cjogxz 1587 9 the the DT cord-015369-72cjogxz 1587 10 valveless valveless JJ cord-015369-72cjogxz 1587 11 great great JJ cord-015369-72cjogxz 1587 12 veins vein NNS cord-015369-72cjogxz 1587 13 of of IN cord-015369-72cjogxz 1587 14 the the DT cord-015369-72cjogxz 1587 15 head head NN cord-015369-72cjogxz 1587 16 and and CC cord-015369-72cjogxz 1587 17 neck neck NN cord-015369-72cjogxz 1587 18 occurs occur VBZ cord-015369-72cjogxz 1587 19 , , , cord-015369-72cjogxz 1587 20 the the DT cord-015369-72cjogxz 1587 21 increased increase VBN cord-015369-72cjogxz 1587 22 pressure pressure NN cord-015369-72cjogxz 1587 23 is be VBZ cord-015369-72cjogxz 1587 24 transmited transmit VBN cord-015369-72cjogxz 1587 25 to to IN cord-015369-72cjogxz 1587 26 the the DT cord-015369-72cjogxz 1587 27 capillaries capillary NNS cord-015369-72cjogxz 1587 28 . . . cord-015369-72cjogxz 1588 1 The the DT cord-015369-72cjogxz 1588 2 blood blood NN cord-015369-72cjogxz 1588 3 stagnates stagnate VBZ cord-015369-72cjogxz 1588 4 and and CC cord-015369-72cjogxz 1588 5 desaturates desaturate NNS cord-015369-72cjogxz 1588 6 . . . cord-015369-72cjogxz 1589 1 Characteristic characteristic JJ cord-015369-72cjogxz 1589 2 appearance appearance NN cord-015369-72cjogxz 1589 3 and and CC cord-015369-72cjogxz 1589 4 the the DT cord-015369-72cjogxz 1589 5 patient patient NN cord-015369-72cjogxz 1589 6 's 's POS cord-015369-72cjogxz 1589 7 history history NN cord-015369-72cjogxz 1589 8 are be VBP cord-015369-72cjogxz 1589 9 the the DT cord-015369-72cjogxz 1589 10 most most RBS cord-015369-72cjogxz 1589 11 important important JJ cord-015369-72cjogxz 1589 12 elements element NNS cord-015369-72cjogxz 1589 13 for for IN cord-015369-72cjogxz 1589 14 diagnosis diagnosis NN cord-015369-72cjogxz 1589 15 . . . cord-015369-72cjogxz 1590 1 Laryngeal laryngeal NN cord-015369-72cjogxz 1590 2 swelling swelling NN cord-015369-72cjogxz 1590 3 can can MD cord-015369-72cjogxz 1590 4 be be VB cord-015369-72cjogxz 1590 5 severe severe JJ cord-015369-72cjogxz 1590 6 enough enough RB cord-015369-72cjogxz 1590 7 to to TO cord-015369-72cjogxz 1590 8 make make VB cord-015369-72cjogxz 1590 9 the the DT cord-015369-72cjogxz 1590 10 endotracheal endotracheal NN cord-015369-72cjogxz 1590 11 intubation intubation NN cord-015369-72cjogxz 1590 12 difficult difficult JJ cord-015369-72cjogxz 1590 13 . . . cord-015369-72cjogxz 1591 1 Tinnitus tinnitus NN cord-015369-72cjogxz 1591 2 or or CC cord-015369-72cjogxz 1591 3 temporary temporary JJ cord-015369-72cjogxz 1591 4 deafness deafness NN cord-015369-72cjogxz 1591 5 , , , cord-015369-72cjogxz 1591 6 transient transient JJ cord-015369-72cjogxz 1591 7 or or CC cord-015369-72cjogxz 1591 8 permanent permanent JJ cord-015369-72cjogxz 1591 9 vision vision NN cord-015369-72cjogxz 1591 10 disturbances disturbance NNS cord-015369-72cjogxz 1591 11 and and CC cord-015369-72cjogxz 1591 12 lethargy lethargy NN cord-015369-72cjogxz 1591 13 may may MD cord-015369-72cjogxz 1591 14 occur occur VB cord-015369-72cjogxz 1591 15 . . . cord-015369-72cjogxz 1592 1 Conclusions conclusion NNS cord-015369-72cjogxz 1592 2 . . . cord-015369-72cjogxz 1593 1 Morbidity morbidity NN cord-015369-72cjogxz 1593 2 and and CC cord-015369-72cjogxz 1593 3 mortality mortality NN cord-015369-72cjogxz 1593 4 are be VBP cord-015369-72cjogxz 1593 5 usually usually RB cord-015369-72cjogxz 1593 6 determined determine VBN cord-015369-72cjogxz 1593 7 by by IN cord-015369-72cjogxz 1593 8 the the DT cord-015369-72cjogxz 1593 9 presence presence NN cord-015369-72cjogxz 1593 10 and and CC cord-015369-72cjogxz 1593 11 severity severity NN cord-015369-72cjogxz 1593 12 of of IN cord-015369-72cjogxz 1593 13 associated associated JJ cord-015369-72cjogxz 1593 14 injuries injury NNS cord-015369-72cjogxz 1593 15 . . . cord-015369-72cjogxz 1594 1 Treatment treatment NN cord-015369-72cjogxz 1594 2 should should MD cord-015369-72cjogxz 1594 3 be be VB cord-015369-72cjogxz 1594 4 directed direct VBN cord-015369-72cjogxz 1594 5 toward toward IN cord-015369-72cjogxz 1594 6 associated associated JJ cord-015369-72cjogxz 1594 7 injuries injury NNS cord-015369-72cjogxz 1594 8 . . . cord-015369-72cjogxz 1595 1 Any any DT cord-015369-72cjogxz 1595 2 sign sign NN cord-015369-72cjogxz 1595 3 of of IN cord-015369-72cjogxz 1595 4 airway airway JJ cord-015369-72cjogxz 1595 5 compromise compromise NN cord-015369-72cjogxz 1595 6 requires require VBZ cord-015369-72cjogxz 1595 7 early early JJ cord-015369-72cjogxz 1595 8 intervention intervention NN cord-015369-72cjogxz 1595 9 . . . cord-015369-72cjogxz 1596 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 1596 2 . . . cord-015369-72cjogxz 1597 1 In in IN cord-015369-72cjogxz 1597 2 dieser dieser NNP cord-015369-72cjogxz 1597 3 retrospektiven retrospektiven NNP cord-015369-72cjogxz 1597 4 Studie Studie NNP cord-015369-72cjogxz 1597 5 wird wird NNP cord-015369-72cjogxz 1597 6 der der NNP cord-015369-72cjogxz 1597 7 Frage Frage NNP cord-015369-72cjogxz 1597 8 nachgegangen nachgegangen NN cord-015369-72cjogxz 1597 9 , , , cord-015369-72cjogxz 1597 10 ob ob NNP cord-015369-72cjogxz 1597 11 die die VBP cord-015369-72cjogxz 1597 12 klinischen klinischen NNP cord-015369-72cjogxz 1598 1 und und NNP cord-015369-72cjogxz 1598 2 radiologischen radiologischen NNP cord-015369-72cjogxz 1599 1 Langzeitergebnisse Langzeitergebnisse NNP cord-015369-72cjogxz 1599 2 den den NN cord-015369-72cjogxz 1599 3 prothetischen prothetischen NNP cord-015369-72cjogxz 1599 4 Ersatz ersatz JJ cord-015369-72cjogxz 1599 5 des des FW cord-015369-72cjogxz 1599 6 Radiuskopfes Radiuskopfes NNP cord-015369-72cjogxz 1599 7 in in IN cord-015369-72cjogxz 1599 8 Fällen Fällen NNP cord-015369-72cjogxz 1599 9 von von NNP cord-015369-72cjogxz 1599 10 nicht nicht NNP cord-015369-72cjogxz 1599 11 rekonstruierbaren rekonstruierbaren NNP cord-015369-72cjogxz 1599 12 Radiuskopffrakturen Radiuskopffrakturen NNP cord-015369-72cjogxz 1599 13 sowie sowie NNP cord-015369-72cjogxz 1599 14 von von NNP cord-015369-72cjogxz 1599 15 komplizierten komplizierten NNP cord-015369-72cjogxz 1599 16 Luxationsfrakturen Luxationsfrakturen NNP cord-015369-72cjogxz 1599 17 des des FW cord-015369-72cjogxz 1599 18 Ellbogengelenkes Ellbogengelenkes NNP cord-015369-72cjogxz 1599 19 rechtfertigen rechtfertigen NNP cord-015369-72cjogxz 1599 20 . . . cord-015369-72cjogxz 1600 1 Methodik Methodik NNP cord-015369-72cjogxz 1600 2 . . . cord-015369-72cjogxz 1601 1 Innerhalb Innerhalb NNP cord-015369-72cjogxz 1601 2 eines eines NNP cord-015369-72cjogxz 1602 1 Zeitraumes Zeitraumes NNP cord-015369-72cjogxz 1602 2 von von NNP cord-015369-72cjogxz 1602 3 7 7 CD cord-015369-72cjogxz 1602 4 Jahren Jahren NNP cord-015369-72cjogxz 1602 5 ( ( -LRB- cord-015369-72cjogxz 1602 6 1998 1998 CD cord-015369-72cjogxz 1602 7 ) ) -RRB- cord-015369-72cjogxz 1602 8 ( ( -LRB- cord-015369-72cjogxz 1602 9 1999 1999 CD cord-015369-72cjogxz 1602 10 ) ) -RRB- cord-015369-72cjogxz 1603 1 ( ( -LRB- cord-015369-72cjogxz 1603 2 2000 2000 CD cord-015369-72cjogxz 1603 3 ) ) -RRB- cord-015369-72cjogxz 1604 1 ( ( -LRB- cord-015369-72cjogxz 1604 2 2001 2001 CD cord-015369-72cjogxz 1604 3 ) ) -RRB- cord-015369-72cjogxz 1604 4 ( ( -LRB- cord-015369-72cjogxz 1604 5 2002 2002 CD cord-015369-72cjogxz 1604 6 ) ) -RRB- cord-015369-72cjogxz 1605 1 ( ( -LRB- cord-015369-72cjogxz 1605 2 2003 2003 CD cord-015369-72cjogxz 1605 3 ) ) -RRB- cord-015369-72cjogxz 1606 1 ( ( -LRB- cord-015369-72cjogxz 1606 2 2004 2004 CD cord-015369-72cjogxz 1606 3 ) ) -RRB- cord-015369-72cjogxz 1606 4 wurden wurden NNP cord-015369-72cjogxz 1607 1 13 13 CD cord-015369-72cjogxz 1607 2 Patienten Patienten NNP cord-015369-72cjogxz 1607 3 mit mit NNP cord-015369-72cjogxz 1607 4 derselben derselben NN cord-015369-72cjogxz 1608 1 bipolaren bipolaren NNP cord-015369-72cjogxz 1609 1 Metallprothesentype Metallprothesentype NNP cord-015369-72cjogxz 1609 2 ( ( -LRB- cord-015369-72cjogxz 1609 3 Tornier Tornier NNP cord-015369-72cjogxz 1609 4 SA SA NNP cord-015369-72cjogxz 1609 5 , , , cord-015369-72cjogxz 1609 6 FR FR NNP cord-015369-72cjogxz 1609 7 ) ) -RRB- cord-015369-72cjogxz 1609 8 in in IN cord-015369-72cjogxz 1609 9 zementierter zementierter NNP cord-015369-72cjogxz 1609 10 Technik Technik NNP cord-015369-72cjogxz 1609 11 versorgt versorgt NN cord-015369-72cjogxz 1609 12 . . . cord-015369-72cjogxz 1610 1 Die die VB cord-015369-72cjogxz 1610 2 Indikationen Indikationen NNP cord-015369-72cjogxz 1610 3 waren waren NN cord-015369-72cjogxz 1610 4 : : : cord-015369-72cjogxz 1610 5 Isolierte Isolierte NNP cord-015369-72cjogxz 1610 6 Radiuskopftrümmerfrakturen Radiuskopftrümmerfrakturen NNP cord-015369-72cjogxz 1610 7 ( ( -LRB- cord-015369-72cjogxz 1610 8 Mason Mason NNP cord-015369-72cjogxz 1610 9 III III NNP cord-015369-72cjogxz 1610 10 ; ; : cord-015369-72cjogxz 1610 11 4 4 CD cord-015369-72cjogxz 1610 12 Fälle Fälle NNP cord-015369-72cjogxz 1610 13 , , , cord-015369-72cjogxz 1610 14 Gruppe Gruppe NNP cord-015369-72cjogxz 1610 15 1 1 CD cord-015369-72cjogxz 1610 16 ) ) -RRB- cord-015369-72cjogxz 1610 17 , , , cord-015369-72cjogxz 1610 18 Ellbogenluxationen Ellbogenluxationen NNP cord-015369-72cjogxz 1610 19 mit mit NN cord-015369-72cjogxz 1610 20 begleitenden begleitenden NNP cord-015369-72cjogxz 1610 21 Radiuskopffrakturen Radiuskopffrakturen NNP cord-015369-72cjogxz 1610 22 ( ( -LRB- cord-015369-72cjogxz 1610 23 Mason Mason NNP cord-015369-72cjogxz 1610 24 IV IV NNP cord-015369-72cjogxz 1610 25 ; ; : cord-015369-72cjogxz 1610 26 5 5 CD cord-015369-72cjogxz 1610 27 Fälle Fälle NNP cord-015369-72cjogxz 1610 28 , , , cord-015369-72cjogxz 1610 29 Gruppe Gruppe NNP cord-015369-72cjogxz 1610 30 2 2 CD cord-015369-72cjogxz 1610 31 ) ) -RRB- cord-015369-72cjogxz 1611 1 und und NNP cord-015369-72cjogxz 1612 1 Monteggia Monteggia NNP cord-015369-72cjogxz 1612 2 - - HYPH cord-015369-72cjogxz 1612 3 Verletzungen Verletzungen NNP cord-015369-72cjogxz 1612 4 ( ( -LRB- cord-015369-72cjogxz 1612 5 4 4 CD cord-015369-72cjogxz 1612 6 Fälle Fälle NNP cord-015369-72cjogxz 1612 7 , , , cord-015369-72cjogxz 1612 8 Gruppe Gruppe NNP cord-015369-72cjogxz 1612 9 3 3 CD cord-015369-72cjogxz 1612 10 ) ) -RRB- cord-015369-72cjogxz 1612 11 . . . cord-015369-72cjogxz 1613 1 In in IN cord-015369-72cjogxz 1613 2 11 11 CD cord-015369-72cjogxz 1613 3 Fällen Fällen NNP cord-015369-72cjogxz 1613 4 erfolgte erfolgte NN cord-015369-72cjogxz 1613 5 der der NN cord-015369-72cjogxz 1613 6 prothetische prothetische NNP cord-015369-72cjogxz 1613 7 Ersatz ersatz JJ cord-015369-72cjogxz 1613 8 primär primär NN cord-015369-72cjogxz 1613 9 , , , cord-015369-72cjogxz 1613 10 in in IN cord-015369-72cjogxz 1613 11 2 2 CD cord-015369-72cjogxz 1613 12 Fällen Fällen NNP cord-015369-72cjogxz 1613 13 nach nach NN cord-015369-72cjogxz 1613 14 vorangegangener vorangegangener NN cord-015369-72cjogxz 1613 15 Osteosynthese Osteosynthese NNP cord-015369-72cjogxz 1613 16 . . . cord-015369-72cjogxz 1614 1 Bei Bei NNP cord-015369-72cjogxz 1614 2 11 11 CD cord-015369-72cjogxz 1615 1 Patienten Patienten NNP cord-015369-72cjogxz 1615 2 wurde wurde VBD cord-015369-72cjogxz 1615 3 eine eine NNP cord-015369-72cjogxz 1615 4 radiologische radiologische NNP cord-015369-72cjogxz 1615 5 und und NNP cord-015369-72cjogxz 1615 6 klinische klinische NNP cord-015369-72cjogxz 1615 7 Nachuntersuchung Nachuntersuchung NNP cord-015369-72cjogxz 1615 8 nach nach NNP cord-015369-72cjogxz 1615 9 durchschnittlich durchschnittlich NNP cord-015369-72cjogxz 1615 10 6 6 CD cord-015369-72cjogxz 1615 11 Jahren Jahren NNP cord-015369-72cjogxz 1615 12 ( ( -LRB- cord-015369-72cjogxz 1615 13 4 4 CD cord-015369-72cjogxz 1615 14 - - SYM cord-015369-72cjogxz 1615 15 10 10 CD cord-015369-72cjogxz 1615 16 Jahre Jahre NNP cord-015369-72cjogxz 1615 17 ) ) -RRB- cord-015369-72cjogxz 1615 18 durchgeführt durchgeführt NN cord-015369-72cjogxz 1615 19 . . . cord-015369-72cjogxz 1616 1 Das Das NNP cord-015369-72cjogxz 1616 2 funktionelle funktionelle NNP cord-015369-72cjogxz 1617 1 Ergebnis Ergebnis NNP cord-015369-72cjogxz 1617 2 wurde wurde VBD cord-015369-72cjogxz 1617 3 anhand anhand NNP cord-015369-72cjogxz 1617 4 des des NNP cord-015369-72cjogxz 1617 5 Scores Scores NNP cord-015369-72cjogxz 1617 6 von von NNP cord-015369-72cjogxz 1617 7 Geel Geel NNP cord-015369-72cjogxz 1617 8 und und NNP cord-015369-72cjogxz 1617 9 Palmer Palmer NNP cord-015369-72cjogxz 1617 10 ( ( -LRB- cord-015369-72cjogxz 1617 11 CORR CORR NNP cord-015369-72cjogxz 1617 12 1992 1992 CD cord-015369-72cjogxz 1617 13 ) ) -RRB- cord-015369-72cjogxz 1617 14 erhoben erhoben NNP cord-015369-72cjogxz 1617 15 . . . cord-015369-72cjogxz 1618 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1618 2 . . . cord-015369-72cjogxz 1619 1 Radiologisch Radiologisch NNP cord-015369-72cjogxz 1619 2 zeigte zeigte NNP cord-015369-72cjogxz 1619 3 sich sich NNP cord-015369-72cjogxz 1619 4 in in IN cord-015369-72cjogxz 1619 5 keinem keinem NNP cord-015369-72cjogxz 1619 6 Fall Fall NNP cord-015369-72cjogxz 1619 7 ein ein NNP cord-015369-72cjogxz 1619 8 Hinweis Hinweis NNP cord-015369-72cjogxz 1619 9 auf auf NNP cord-015369-72cjogxz 1619 10 eine eine NNP cord-015369-72cjogxz 1619 11 Veränderung Veränderung NNP cord-015369-72cjogxz 1619 12 der der NNP cord-015369-72cjogxz 1619 13 Prothese prothese JJ cord-015369-72cjogxz 1619 14 bzw bzw NN cord-015369-72cjogxz 1619 15 . . . cord-015369-72cjogxz 1620 1 deren deren NNP cord-015369-72cjogxz 1620 2 Position Position NNP cord-015369-72cjogxz 1620 3 . . . cord-015369-72cjogxz 1621 1 I -PRON- PRP cord-015369-72cjogxz 1621 2 m be VBP cord-015369-72cjogxz 1621 3 Bereich Bereich NNP cord-015369-72cjogxz 1621 4 des des NNP cord-015369-72cjogxz 1621 5 Humeroradialgelenkes Humeroradialgelenkes NNP cord-015369-72cjogxz 1621 6 fanden fanden NNP cord-015369-72cjogxz 1621 7 sich sich NNP cord-015369-72cjogxz 1621 8 nur nur NNP cord-015369-72cjogxz 1621 9 in in IN cord-015369-72cjogxz 1621 10 einzelnen einzelnen NNP cord-015369-72cjogxz 1622 1 Fällen Fällen NNP cord-015369-72cjogxz 1622 2 angedeutete angedeutete NN cord-015369-72cjogxz 1622 3 Zeichen Zeichen NNP cord-015369-72cjogxz 1622 4 einer einer NNP cord-015369-72cjogxz 1622 5 Arthrose Arthrose NNP cord-015369-72cjogxz 1622 6 , , , cord-015369-72cjogxz 1622 7 das das NNP cord-015369-72cjogxz 1622 8 Capitulum Capitulum NNP cord-015369-72cjogxz 1622 9 radiale radiale NNP cord-015369-72cjogxz 1622 10 humeri humeri NNP cord-015369-72cjogxz 1622 11 wies wy NNS cord-015369-72cjogxz 1622 12 in in IN cord-015369-72cjogxz 1622 13 wenigen wenigen NNP cord-015369-72cjogxz 1622 14 Fällen Fällen NNP cord-015369-72cjogxz 1622 15 eine eine NNP cord-015369-72cjogxz 1622 16 zentrale zentrale NNP cord-015369-72cjogxz 1622 17 Abflachung Abflachung NNP cord-015369-72cjogxz 1622 18 auf auf NNP cord-015369-72cjogxz 1622 19 . . . cord-015369-72cjogxz 1623 1 Das Das NNP cord-015369-72cjogxz 1623 2 proximale proximale NNP cord-015369-72cjogxz 1624 1 Radioulnargelenk Radioulnargelenk NNP cord-015369-72cjogxz 1624 2 war war NN cord-015369-72cjogxz 1624 3 in in IN cord-015369-72cjogxz 1624 4 allen allen NNP cord-015369-72cjogxz 1624 5 Fällen Fällen NNP cord-015369-72cjogxz 1624 6 radiologisch radiologisch NN cord-015369-72cjogxz 1624 7 unauffällig unauffällig NNP cord-015369-72cjogxz 1624 8 . . . cord-015369-72cjogxz 1625 1 Geringgradige Geringgradige NNP cord-015369-72cjogxz 1625 2 periartikuläre periartikuläre NN cord-015369-72cjogxz 1625 3 Verkalkungen Verkalkungen NNP cord-015369-72cjogxz 1625 4 fanden fanden NNP cord-015369-72cjogxz 1625 5 sich sich NNP cord-015369-72cjogxz 1625 6 hauptsächlich hauptsächlich NNP cord-015369-72cjogxz 1626 1 i -PRON- PRP cord-015369-72cjogxz 1626 2 m be VBP cord-015369-72cjogxz 1626 3 Bereich Bereich NNP cord-015369-72cjogxz 1626 4 der der NNP cord-015369-72cjogxz 1626 5 ventralen ventralen NNP cord-015369-72cjogxz 1626 6 Gelenkskapsel Gelenkskapsel NNP cord-015369-72cjogxz 1626 7 . . . cord-015369-72cjogxz 1627 1 Unter Unter NNP cord-015369-72cjogxz 1627 2 Anwendung Anwendung NNP cord-015369-72cjogxz 1627 3 des des XX cord-015369-72cjogxz 1628 1 o.a o.a NNP cord-015369-72cjogxz 1628 2 . . . cord-015369-72cjogxz 1629 1 klinischen klinischen NNP cord-015369-72cjogxz 1629 2 Scores Scores NNP cord-015369-72cjogxz 1629 3 , , , cord-015369-72cjogxz 1629 4 der der NNP cord-015369-72cjogxz 1629 5 sich sich NNP cord-015369-72cjogxz 1629 6 aus aus NNP cord-015369-72cjogxz 1629 7 den den NNP cord-015369-72cjogxz 1629 8 Kriterien Kriterien NNP cord-015369-72cjogxz 1629 9 Bewegungsumfang Bewegungsumfang NNP cord-015369-72cjogxz 1629 10 , , , cord-015369-72cjogxz 1629 11 Gelenksstabilität Gelenksstabilität NNP cord-015369-72cjogxz 1629 12 , , , cord-015369-72cjogxz 1629 13 Kraft Kraft NNP cord-015369-72cjogxz 1629 14 und und IN cord-015369-72cjogxz 1629 15 Schmerzen Schmerzen NNP cord-015369-72cjogxz 1629 16 zusammensetzt zusammensetzt VBD cord-015369-72cjogxz 1629 17 , , , cord-015369-72cjogxz 1629 18 fanden fanden NNP cord-015369-72cjogxz 1629 19 sich sich NNP cord-015369-72cjogxz 1629 20 exzellente exzellente NNP cord-015369-72cjogxz 1630 1 Resultate Resultate NNP cord-015369-72cjogxz 1630 2 bei bei NNP cord-015369-72cjogxz 1630 3 allen allen NNP cord-015369-72cjogxz 1630 4 Patienten Patienten NNP cord-015369-72cjogxz 1630 5 der der NNP cord-015369-72cjogxz 1630 6 Gruppen Gruppen NNP cord-015369-72cjogxz 1630 7 1 1 CD cord-015369-72cjogxz 1630 8 und und IN cord-015369-72cjogxz 1630 9 2 2 CD cord-015369-72cjogxz 1630 10 . . . cord-015369-72cjogxz 1631 1 Bei Bei NNP cord-015369-72cjogxz 1631 2 keinem keinem NN cord-015369-72cjogxz 1631 3 dieser dieser NNP cord-015369-72cjogxz 1631 4 Patienten Patienten NNP cord-015369-72cjogxz 1631 5 bestand bestand NNP cord-015369-72cjogxz 1631 6 eine eine NNP cord-015369-72cjogxz 1631 7 Gelenksinstabilität Gelenksinstabilität NNP cord-015369-72cjogxz 1631 8 . . . cord-015369-72cjogxz 1632 1 Die die VB cord-015369-72cjogxz 1633 1 Patienten Patienten NNP cord-015369-72cjogxz 1633 2 der der NNP cord-015369-72cjogxz 1633 3 Gruppe Gruppe NNP cord-015369-72cjogxz 1633 4 3 3 CD cord-015369-72cjogxz 1634 1 ( ( -LRB- cord-015369-72cjogxz 1634 2 Monteggia Monteggia NNP cord-015369-72cjogxz 1634 3 - - HYPH cord-015369-72cjogxz 1634 4 Verletzungen Verletzungen NNP cord-015369-72cjogxz 1634 5 ) ) -RRB- cord-015369-72cjogxz 1634 6 schnitten schnitten JJ cord-015369-72cjogxz 1634 7 etwas etwas FW cord-015369-72cjogxz 1634 8 schlechter schlechter FW cord-015369-72cjogxz 1634 9 ab ab NNP cord-015369-72cjogxz 1634 10 ( ( -LRB- cord-015369-72cjogxz 1634 11 gutes gutes NNP cord-015369-72cjogxz 1634 12 Resultat Resultat NNP cord-015369-72cjogxz 1634 13 ) ) -RRB- cord-015369-72cjogxz 1634 14 . . . cord-015369-72cjogxz 1635 1 Hauptverantwortlich Hauptverantwortlich NNP cord-015369-72cjogxz 1635 2 dafü dafü NNP cord-015369-72cjogxz 1636 1 r r LS cord-015369-72cjogxz 1636 2 waren waren NNP cord-015369-72cjogxz 1636 3 Einschränkungen Einschränkungen NNP cord-015369-72cjogxz 1636 4 in in IN cord-015369-72cjogxz 1636 5 der der NNP cord-015369-72cjogxz 1636 6 Streckung Streckung NNP cord-015369-72cjogxz 1636 7 und und IN cord-015369-72cjogxz 1636 8 den den NNP cord-015369-72cjogxz 1636 9 Umwendbewegungen Umwendbewegungen NNP cord-015369-72cjogxz 1636 10 . . . cord-015369-72cjogxz 1637 1 Subjektiv subjektiv JJ cord-015369-72cjogxz 1637 2 waren waren NNP cord-015369-72cjogxz 1637 3 alle alle NNP cord-015369-72cjogxz 1637 4 Patienten Patienten NNP cord-015369-72cjogxz 1637 5 mit mit NNP cord-015369-72cjogxz 1637 6 dem dem NNP cord-015369-72cjogxz 1637 7 Ergebnis Ergebnis NNP cord-015369-72cjogxz 1637 8 zufrieden zufrieden NNP cord-015369-72cjogxz 1637 9 und und XX cord-015369-72cjogxz 1638 1 konnten konnten NNP cord-015369-72cjogxz 1638 2 ihre ihre NNP cord-015369-72cjogxz 1638 3 vorherigen vorherigen NNP cord-015369-72cjogxz 1638 4 beruflichen beruflichen NNP cord-015369-72cjogxz 1639 1 und und NNP cord-015369-72cjogxz 1639 2 Freizeitaktivitäten Freizeitaktivitäten NNP cord-015369-72cjogxz 1639 3 ohne ohne NNP cord-015369-72cjogxz 1639 4 wesentliche wesentliche NNP cord-015369-72cjogxz 1639 5 Einschränkung Einschränkung NNP cord-015369-72cjogxz 1639 6 wieder wieder NNP cord-015369-72cjogxz 1639 7 ausü ausü NNP cord-015369-72cjogxz 1639 8 ben ben NNP cord-015369-72cjogxz 1639 9 . . . cord-015369-72cjogxz 1640 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1640 2 . . . cord-015369-72cjogxz 1641 1 Obwohl Obwohl NNP cord-015369-72cjogxz 1641 2 die die VBP cord-015369-72cjogxz 1641 3 Implantation implantation NN cord-015369-72cjogxz 1641 4 einer einer NN cord-015369-72cjogxz 1642 1 Radiuskopfprothese Radiuskopfprothese NNP cord-015369-72cjogxz 1642 2 eine eine NNP cord-015369-72cjogxz 1642 3 sehr sehr JJ cord-015369-72cjogxz 1642 4 selten selten NNP cord-015369-72cjogxz 1642 5 durchgeführte durchgeführte NNP cord-015369-72cjogxz 1642 6 Operation Operation NNP cord-015369-72cjogxz 1642 7 ist ist NNP cord-015369-72cjogxz 1643 1 , , , cord-015369-72cjogxz 1643 2 beweisen beweisen NNP cord-015369-72cjogxz 1643 3 die die VB cord-015369-72cjogxz 1643 4 guten guten NNP cord-015369-72cjogxz 1644 1 Resultate Resultate NNP cord-015369-72cjogxz 1644 2 die die VB cord-015369-72cjogxz 1644 3 Sicherheit Sicherheit NNP cord-015369-72cjogxz 1644 4 der der NN cord-015369-72cjogxz 1644 5 Methode Methode NNP cord-015369-72cjogxz 1644 6 . . . cord-015369-72cjogxz 1645 1 Die die VB cord-015369-72cjogxz 1645 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1645 3 scheinen scheinen NNP cord-015369-72cjogxz 1645 4 eher eher NNP cord-015369-72cjogxz 1645 5 durch durch NNP cord-015369-72cjogxz 1645 6 die die NNP cord-015369-72cjogxz 1646 1 Schädigung Schädigung NNP cord-015369-72cjogxz 1646 2 des des FW cord-015369-72cjogxz 1646 3 Ellbogengelenkes Ellbogengelenkes NNP cord-015369-72cjogxz 1646 4 infolge infolge NNP cord-015369-72cjogxz 1646 5 des des NNP cord-015369-72cjogxz 1646 6 initialen initialen NNP cord-015369-72cjogxz 1646 7 Traumas Traumas NNP cord-015369-72cjogxz 1646 8 als als NN cord-015369-72cjogxz 1647 1 durch durch NNP cord-015369-72cjogxz 1647 2 die die NNP cord-015369-72cjogxz 1648 1 Prothese Prothese NNP cord-015369-72cjogxz 1648 2 selbst selbst NN cord-015369-72cjogxz 1648 3 beeinflusst beeinflusst NNP cord-015369-72cjogxz 1648 4 zu zu NNP cord-015369-72cjogxz 1648 5 werden werden NNP cord-015369-72cjogxz 1648 6 . . . cord-015369-72cjogxz 1649 1 Die die VB cord-015369-72cjogxz 1649 2 Radiuskopfprothese Radiuskopfprothese NNP cord-015369-72cjogxz 1649 3 sollte sollte NNP cord-015369-72cjogxz 1649 4 daher daher NNP cord-015369-72cjogxz 1649 5 bei bei NNP cord-015369-72cjogxz 1649 6 entsprechender entsprechender NNP cord-015369-72cjogxz 1650 1 Indikation Indikation NNP cord-015369-72cjogxz 1651 1 i i PRP cord-015369-72cjogxz 1652 1 m m NNP cord-015369-72cjogxz 1652 2 Sinne Sinne NNP cord-015369-72cjogxz 1653 1 einer einer NNP cord-015369-72cjogxz 1653 2 primären primären NNP cord-015369-72cjogxz 1654 1 Definitivversorgung Definitivversorgung NNP cord-015369-72cjogxz 1654 2 eingesetzt eingesetzt VBD cord-015369-72cjogxz 1654 3 werden werden NNP cord-015369-72cjogxz 1655 1 und und NNP cord-015369-72cjogxz 1656 1 ihren ihren NNP cord-015369-72cjogxz 1656 2 festen festen NNP cord-015369-72cjogxz 1656 3 Platz Platz NNP cord-015369-72cjogxz 1657 1 i -PRON- PRP cord-015369-72cjogxz 1657 2 m be VBP cord-015369-72cjogxz 1657 3 Implantatlager Implantatlager NNP cord-015369-72cjogxz 1657 4 jeder jeder NNP cord-015369-72cjogxz 1657 5 größeren größeren NNP cord-015369-72cjogxz 1657 6 Unfallabteilung Unfallabteilung NNP cord-015369-72cjogxz 1657 7 finden finden NNP cord-015369-72cjogxz 1657 8 . . . cord-015369-72cjogxz 1658 1 Background background NN cord-015369-72cjogxz 1658 2 . . . cord-015369-72cjogxz 1659 1 Gastric gastric JJ cord-015369-72cjogxz 1659 2 bypass bypass NN cord-015369-72cjogxz 1659 3 after after IN cord-015369-72cjogxz 1659 4 VBG VBG NNP cord-015369-72cjogxz 1659 5 often often RB cord-015369-72cjogxz 1659 6 is be VBZ cord-015369-72cjogxz 1659 7 a a DT cord-015369-72cjogxz 1659 8 technically technically RB cord-015369-72cjogxz 1659 9 difficult difficult JJ cord-015369-72cjogxz 1659 10 and and CC cord-015369-72cjogxz 1659 11 demanding demanding JJ cord-015369-72cjogxz 1659 12 procedure procedure NN cord-015369-72cjogxz 1659 13 . . . cord-015369-72cjogxz 1660 1 Postoperative postoperative JJ cord-015369-72cjogxz 1660 2 morbidity morbidity NN cord-015369-72cjogxz 1660 3 and and CC cord-015369-72cjogxz 1660 4 mortality mortality NN cord-015369-72cjogxz 1660 5 is be VBZ cord-015369-72cjogxz 1660 6 significantly significantly RB cord-015369-72cjogxz 1660 7 higher high JJR cord-015369-72cjogxz 1660 8 compared compare VBN cord-015369-72cjogxz 1660 9 to to IN cord-015369-72cjogxz 1660 10 primary primary JJ cord-015369-72cjogxz 1660 11 bypass bypass NN cord-015369-72cjogxz 1660 12 . . . cord-015369-72cjogxz 1661 1 Massive massive JJ cord-015369-72cjogxz 1661 2 adhesions adhesion NNS cord-015369-72cjogxz 1661 3 and and CC cord-015369-72cjogxz 1661 4 scar scar NN cord-015369-72cjogxz 1661 5 formation formation NN cord-015369-72cjogxz 1661 6 at at IN cord-015369-72cjogxz 1661 7 the the DT cord-015369-72cjogxz 1661 8 gastro gastro JJ cord-015369-72cjogxz 1661 9 - - JJ cord-015369-72cjogxz 1661 10 esophageal esophageal JJ cord-015369-72cjogxz 1661 11 junction junction NN cord-015369-72cjogxz 1661 12 are be VBP cord-015369-72cjogxz 1661 13 responsible responsible JJ cord-015369-72cjogxz 1661 14 for for IN cord-015369-72cjogxz 1661 15 the the DT cord-015369-72cjogxz 1661 16 difficulties difficulty NNS cord-015369-72cjogxz 1661 17 in in IN cord-015369-72cjogxz 1661 18 this this DT cord-015369-72cjogxz 1661 19 procedure procedure NN cord-015369-72cjogxz 1661 20 . . . cord-015369-72cjogxz 1662 1 Scopinaro Scopinaro NNP cord-015369-72cjogxz 1662 2 's 's POS cord-015369-72cjogxz 1662 3 procedure procedure NN cord-015369-72cjogxz 1662 4 ( ( -LRB- cord-015369-72cjogxz 1662 5 a a DT cord-015369-72cjogxz 1662 6 distal distal JJ cord-015369-72cjogxz 1662 7 gastrectomy gastrectomy NN cord-015369-72cjogxz 1662 8 with with IN cord-015369-72cjogxz 1662 9 gastro gastro JJ cord-015369-72cjogxz 1662 10 - - JJ cord-015369-72cjogxz 1662 11 ileostomy ileostomy NN cord-015369-72cjogxz 1662 12 ) ) -RRB- cord-015369-72cjogxz 1662 13 offers offer VBZ cord-015369-72cjogxz 1662 14 the the DT cord-015369-72cjogxz 1662 15 great great JJ cord-015369-72cjogxz 1662 16 advantage advantage NN cord-015369-72cjogxz 1662 17 of of IN cord-015369-72cjogxz 1662 18 sparing spare VBG cord-015369-72cjogxz 1662 19 the the DT cord-015369-72cjogxz 1662 20 gastro gastro JJ cord-015369-72cjogxz 1662 21 - - JJ cord-015369-72cjogxz 1662 22 esophageal esophageal JJ cord-015369-72cjogxz 1662 23 junction junction NN cord-015369-72cjogxz 1662 24 and and CC cord-015369-72cjogxz 1662 25 avoiding avoid VBG cord-015369-72cjogxz 1662 26 staple staple JJ cord-015369-72cjogxz 1662 27 lines line NNS cord-015369-72cjogxz 1662 28 through through IN cord-015369-72cjogxz 1662 29 scary scary JJ cord-015369-72cjogxz 1662 30 tissues tissue NNS cord-015369-72cjogxz 1662 31 . . . cord-015369-72cjogxz 1663 1 This this DT cord-015369-72cjogxz 1663 2 operation operation NN cord-015369-72cjogxz 1663 3 may may MD cord-015369-72cjogxz 1663 4 represent represent VB cord-015369-72cjogxz 1663 5 a a DT cord-015369-72cjogxz 1663 6 safe safe JJ cord-015369-72cjogxz 1663 7 alternative alternative NN cord-015369-72cjogxz 1663 8 to to IN cord-015369-72cjogxz 1663 9 gastric gastric JJ cord-015369-72cjogxz 1663 10 bypass bypass NN cord-015369-72cjogxz 1663 11 after after IN cord-015369-72cjogxz 1663 12 VBG VBG NNP cord-015369-72cjogxz 1663 13 . . . cord-015369-72cjogxz 1664 1 A a DT cord-015369-72cjogxz 1664 2 video video NN cord-015369-72cjogxz 1664 3 of of IN cord-015369-72cjogxz 1664 4 Scorpinaro Scorpinaro NNP cord-015369-72cjogxz 1664 5 's 's POS cord-015369-72cjogxz 1664 6 procedure procedure NN cord-015369-72cjogxz 1664 7 after after IN cord-015369-72cjogxz 1664 8 VBG VBG NNP cord-015369-72cjogxz 1664 9 will will MD cord-015369-72cjogxz 1664 10 be be VB cord-015369-72cjogxz 1664 11 presented present VBN cord-015369-72cjogxz 1664 12 . . . cord-015369-72cjogxz 1665 1 Trotzdem Trotzdem NNP cord-015369-72cjogxz 1665 2 kann kann NNP cord-015369-72cjogxz 1665 3 durch durch NNP cord-015369-72cjogxz 1665 4 eine eine NNP cord-015369-72cjogxz 1665 5 Operation Operation NNP cord-015369-72cjogxz 1665 6 nicht nicht NNP cord-015369-72cjogxz 1665 7 in in IN cord-015369-72cjogxz 1665 8 allen allen NNP cord-015369-72cjogxz 1665 9 Fällen Fällen NNP cord-015369-72cjogxz 1665 10 ein ein NNP cord-015369-72cjogxz 1665 11 Rezidiv Rezidiv NNP cord-015369-72cjogxz 1665 12 verhindert verhindert JJ cord-015369-72cjogxz 1665 13 werden werden NNP cord-015369-72cjogxz 1665 14 . . . cord-015369-72cjogxz 1666 1 Diese Diese NNP cord-015369-72cjogxz 1666 2 Beobachtung Beobachtung NNP cord-015369-72cjogxz 1667 1 und und IN cord-015369-72cjogxz 1667 2 das das NNP cord-015369-72cjogxz 1667 3 Streben Streben NNP cord-015369-72cjogxz 1667 4 nach nach NNP cord-015369-72cjogxz 1667 5 noch noch NNP cord-015369-72cjogxz 1667 6 geringerer geringerer NNP cord-015369-72cjogxz 1667 7 Invasivität Invasivität NNP cord-015369-72cjogxz 1667 8 führten führten NNP cord-015369-72cjogxz 1667 9 zur zur NNP cord-015369-72cjogxz 1667 10 Entwicklung Entwicklung NNP cord-015369-72cjogxz 1667 11 endovenöser endovenöser NNP cord-015369-72cjogxz 1667 12 Therapien Therapien NNP cord-015369-72cjogxz 1667 13 . . . cord-015369-72cjogxz 1668 1 Allen Allen NNP cord-015369-72cjogxz 1668 2 gemein gemein NNP cord-015369-72cjogxz 1668 3 ist ist NNP cord-015369-72cjogxz 1668 4 , , , cord-015369-72cjogxz 1668 5 dass dass NNP cord-015369-72cjogxz 1668 6 sie sie NNP cord-015369-72cjogxz 1668 7 ultraschallgesteuert ultraschallgesteuert NNP cord-015369-72cjogxz 1668 8 durchgeführt durchgeführt NNP cord-015369-72cjogxz 1669 1 werden werden NNP cord-015369-72cjogxz 1669 2 . . . cord-015369-72cjogxz 1670 1 Es Es NNP cord-015369-72cjogxz 1670 2 kommt kommt NNP cord-015369-72cjogxz 1670 3 zur zur NNP cord-015369-72cjogxz 1670 4 Induktion Induktion NNP cord-015369-72cjogxz 1671 1 einer einer NNP cord-015369-72cjogxz 1671 2 thermischen thermischen NNP cord-015369-72cjogxz 1672 1 oder oder NNP cord-015369-72cjogxz 1672 2 chemischen chemischen NNP cord-015369-72cjogxz 1672 3 Phlebitis Phlebitis NNP cord-015369-72cjogxz 1672 4 , , , cord-015369-72cjogxz 1672 5 die die VBP cord-015369-72cjogxz 1672 6 in in IN cord-015369-72cjogxz 1672 7 weiterer weiterer JJ cord-015369-72cjogxz 1672 8 Folge folge NN cord-015369-72cjogxz 1672 9 zu zu NNP cord-015369-72cjogxz 1672 10 einer einer NNP cord-015369-72cjogxz 1672 11 Obliteration obliteration NN cord-015369-72cjogxz 1672 12 der der NN cord-015369-72cjogxz 1672 13 Vene Vene NNP cord-015369-72cjogxz 1672 14 führt führt NNP cord-015369-72cjogxz 1672 15 . . . cord-015369-72cjogxz 1673 1 Der Der NNP cord-015369-72cjogxz 1673 2 Vorteil Vorteil NNP cord-015369-72cjogxz 1673 3 dieser dieser NNP cord-015369-72cjogxz 1673 4 neuen neuen NNP cord-015369-72cjogxz 1673 5 Therapieoptionen Therapieoptionen NNP cord-015369-72cjogxz 1673 6 ist ist NNP cord-015369-72cjogxz 1673 7 , , , cord-015369-72cjogxz 1673 8 dass dass NNP cord-015369-72cjogxz 1673 9 sie sie NNP cord-015369-72cjogxz 1673 10 in in IN cord-015369-72cjogxz 1673 11 lokaler lokaler NNP cord-015369-72cjogxz 1673 12 oder oder NNP cord-015369-72cjogxz 1673 13 Tumeszenzanästhesie Tumeszenzanästhesie NNP cord-015369-72cjogxz 1673 14 ambulant ambulant JJ cord-015369-72cjogxz 1673 15 durchgeführt durchgeführt NN cord-015369-72cjogxz 1673 16 werden werden NNP cord-015369-72cjogxz 1673 17 können können NNP cord-015369-72cjogxz 1673 18 . . . cord-015369-72cjogxz 1674 1 Die die VB cord-015369-72cjogxz 1674 2 kurz kurz NNP cord-015369-72cjogxz 1674 3 - - HYPH cord-015369-72cjogxz 1674 4 und und NNP cord-015369-72cjogxz 1675 1 mittelfristigen mittelfristigen NNP cord-015369-72cjogxz 1675 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1675 3 nach nach NNP cord-015369-72cjogxz 1675 4 Laser Laser NNP cord-015369-72cjogxz 1675 5 - - HYPH cord-015369-72cjogxz 1675 6 und und NNP cord-015369-72cjogxz 1675 7 Radiofrequenzablation Radiofrequenzablation NNP cord-015369-72cjogxz 1675 8 sind sind NNPS cord-015369-72cjogxz 1675 9 in in IN cord-015369-72cjogxz 1675 10 prospektiven prospektiven NNP cord-015369-72cjogxz 1676 1 und und NNP cord-015369-72cjogxz 1676 2 retrospektiven retrospektiven NNP cord-015369-72cjogxz 1677 1 Untersuchungen Untersuchungen NNP cord-015369-72cjogxz 1677 2 mit mit NNP cord-015369-72cjogxz 1677 3 den den NNP cord-015369-72cjogxz 1677 4 Ergebnissen Ergebnissen NNP cord-015369-72cjogxz 1677 5 nach nach NNP cord-015369-72cjogxz 1677 6 einer einer NNP cord-015369-72cjogxz 1677 7 , , , cord-015369-72cjogxz 1677 8 , , , cord-015369-72cjogxz 1677 9 klassischen klassischen NNP cord-015369-72cjogxz 1677 10 Varizenoperation Varizenoperation NNP cord-015369-72cjogxz 1677 11 ' ' POS cord-015369-72cjogxz 1677 12 ' ' '' cord-015369-72cjogxz 1677 13 vergleichbar vergleichbar NN cord-015369-72cjogxz 1677 14 . . . cord-015369-72cjogxz 1678 1 Langzeitbeobachtungen Langzeitbeobachtungen NNP cord-015369-72cjogxz 1678 2 über über NNP cord-015369-72cjogxz 1678 3 5 5 CD cord-015369-72cjogxz 1678 4 Jahre Jahre NNP cord-015369-72cjogxz 1679 1 liegen liegen NNP cord-015369-72cjogxz 1679 2 nur nur NNP cord-015369-72cjogxz 1679 3 nach nach NNP cord-015369-72cjogxz 1679 4 solchen solchen NNP cord-015369-72cjogxz 1679 5 4-Schritt 4-Schritt NNP cord-015369-72cjogxz 1679 6 - - HYPH cord-015369-72cjogxz 1679 7 Varizenoperationen Varizenoperationen NNP cord-015369-72cjogxz 1679 8 vor vor NNP cord-015369-72cjogxz 1679 9 . . . cord-015369-72cjogxz 1680 1 Die die VB cord-015369-72cjogxz 1681 1 Schaumsklerosierung Schaumsklerosierung NNP cord-015369-72cjogxz 1681 2 ist ist NN cord-015369-72cjogxz 1682 1 eine eine NNP cord-015369-72cjogxz 1682 2 wenig wenig NNP cord-015369-72cjogxz 1682 3 invasive invasive JJ cord-015369-72cjogxz 1683 1 und und NNP cord-015369-72cjogxz 1684 1 billige billige NNP cord-015369-72cjogxz 1684 2 Therapieoption Therapieoption NNP cord-015369-72cjogxz 1684 3 , , , cord-015369-72cjogxz 1684 4 hat hat NN cord-015369-72cjogxz 1684 5 aber aber NNP cord-015369-72cjogxz 1684 6 eine eine FW cord-015369-72cjogxz 1684 7 hohe hohe NNP cord-015369-72cjogxz 1684 8 Rezidivrate Rezidivrate NNP cord-015369-72cjogxz 1684 9 . . . cord-015369-72cjogxz 1685 1 Somit Somit NNP cord-015369-72cjogxz 1685 2 stellt stellt NNP cord-015369-72cjogxz 1686 1 die die VB cord-015369-72cjogxz 1686 2 klassische klassische NNP cord-015369-72cjogxz 1686 3 Varizenoperation Varizenoperation NNP cord-015369-72cjogxz 1686 4 aufgrund aufgrund NNP cord-015369-72cjogxz 1686 5 der der NNP cord-015369-72cjogxz 1686 6 guten guten NNP cord-015369-72cjogxz 1686 7 kurz- kurz- XX cord-015369-72cjogxz 1687 1 , , , cord-015369-72cjogxz 1687 2 mittel mittel NNP cord-015369-72cjogxz 1687 3 - - HYPH cord-015369-72cjogxz 1687 4 und und NNP cord-015369-72cjogxz 1687 5 langfristigen langfristigen NNP cord-015369-72cjogxz 1687 6 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1687 7 immer immer NNP cord-015369-72cjogxz 1687 8 noch noch NNP cord-015369-72cjogxz 1687 9 den den NNP cord-015369-72cjogxz 1687 10 , , , cord-015369-72cjogxz 1687 11 , , , cord-015369-72cjogxz 1687 12 Goldstandard Goldstandard NNP cord-015369-72cjogxz 1687 13 ' ' POS cord-015369-72cjogxz 1687 14 ' ' '' cord-015369-72cjogxz 1687 15 in in IN cord-015369-72cjogxz 1687 16 der der NNP cord-015369-72cjogxz 1687 17 Therapie Therapie NNP cord-015369-72cjogxz 1687 18 eines eines NNP cord-015369-72cjogxz 1687 19 Varizenleidens Varizenleidens NNP cord-015369-72cjogxz 1687 20 dar dar NNP cord-015369-72cjogxz 1687 21 . . . cord-015369-72cjogxz 1688 1 Die die VB cord-015369-72cjogxz 1688 2 4-Schritt 4-schritt CD cord-015369-72cjogxz 1688 3 - - HYPH cord-015369-72cjogxz 1688 4 Varizenoperation Varizenoperation NNP cord-015369-72cjogxz 1688 5 wird wird NNP cord-015369-72cjogxz 1688 6 heute heute NN cord-015369-72cjogxz 1689 1 gering gering NNP cord-015369-72cjogxz 1689 2 invasiv invasiv NNP cord-015369-72cjogxz 1689 3 , , , cord-015369-72cjogxz 1689 4 kosmetisch kosmetisch NNP cord-015369-72cjogxz 1689 5 orientiert orientiert NNP cord-015369-72cjogxz 1689 6 , , , cord-015369-72cjogxz 1690 1 mit mit NNP cord-015369-72cjogxz 1690 2 endovaskulären endovaskulären NNP cord-015369-72cjogxz 1690 3 gewebsschonenden gewebsschonenden NNP cord-015369-72cjogxz 1690 4 Stripping Stripping NNP cord-015369-72cjogxz 1690 5 - - HYPH cord-015369-72cjogxz 1690 6 Operationstechniken Operationstechniken NNP cord-015369-72cjogxz 1690 7 und und IN cord-015369-72cjogxz 1690 8 sicherer sicherer NNP cord-015369-72cjogxz 1690 9 präoperativer präoperativer NNP cord-015369-72cjogxz 1690 10 Therapie Therapie NNP cord-015369-72cjogxz 1690 11 durchgeführt durchgeführt NN cord-015369-72cjogxz 1690 12 . . . cord-015369-72cjogxz 1691 1 SD SD NNP cord-015369-72cjogxz 1691 2 3 3 CD cord-015369-72cjogxz 1691 3 , , , cord-015369-72cjogxz 1691 4 8) 8) NNP cord-015369-72cjogxz 1692 1 Schmerzen Schmerzen NNP cord-015369-72cjogxz 1692 2 in in IN cord-015369-72cjogxz 1692 3 Verlauf Verlauf NNP cord-015369-72cjogxz 1692 4 der der NNP cord-015369-72cjogxz 1692 5 behandelten behandelten NNP cord-015369-72cjogxz 1692 6 Vene Vene NNP cord-015369-72cjogxz 1693 1 und und IN cord-015369-72cjogxz 1693 2 nahmen nahmen NNP cord-015369-72cjogxz 1694 1 i -PRON- PRP cord-015369-72cjogxz 1694 2 m be VBP cord-015369-72cjogxz 1694 3 Mittel Mittel NNP cord-015369-72cjogxz 1694 4 2,3 2,3 CD cord-015369-72cjogxz 1694 5 Schmerztabletten Schmerztabletten NNP cord-015369-72cjogxz 1694 6 ( ( -LRB- cord-015369-72cjogxz 1694 7 SD sd NN cord-015369-72cjogxz 1694 8 4,2 4,2 CD cord-015369-72cjogxz 1694 9 ) ) -RRB- cord-015369-72cjogxz 1695 1 ein ein NNP cord-015369-72cjogxz 1695 2 . . . cord-015369-72cjogxz 1696 1 I -PRON- PRP cord-015369-72cjogxz 1696 2 m be VBP cord-015369-72cjogxz 1696 3 Mittel Mittel NNP cord-015369-72cjogxz 1696 4 konnte konnte NNP cord-015369-72cjogxz 1696 5 nach nach NN cord-015369-72cjogxz 1696 6 1,6 1,6 CD cord-015369-72cjogxz 1696 7 Tage tage NN cord-015369-72cjogxz 1696 8 ( ( -LRB- cord-015369-72cjogxz 1696 9 0 0 CD cord-015369-72cjogxz 1696 10 - - SYM cord-015369-72cjogxz 1696 11 5 5 CD cord-015369-72cjogxz 1696 12 Tage Tage NNP cord-015369-72cjogxz 1696 13 ; ; : cord-015369-72cjogxz 1696 14 SD SD NNP cord-015369-72cjogxz 1696 15 1,1 1,1 CD cord-015369-72cjogxz 1696 16 ) ) -RRB- cord-015369-72cjogxz 1696 17 die die VBP cord-015369-72cjogxz 1696 18 täglichen täglichen NN cord-015369-72cjogxz 1697 1 Aktivitäten Aktivitäten NNP cord-015369-72cjogxz 1697 2 normal normal JJ cord-015369-72cjogxz 1697 3 wieder wieder NNP cord-015369-72cjogxz 1697 4 aufgenommen aufgenommen NNP cord-015369-72cjogxz 1697 5 werden werden NNP cord-015369-72cjogxz 1697 6 . . . cord-015369-72cjogxz 1698 1 Bei Bei NNP cord-015369-72cjogxz 1698 2 keinem keinem NNP cord-015369-72cjogxz 1698 3 der der NNP cord-015369-72cjogxz 1698 4 50 50 CD cord-015369-72cjogxz 1698 5 behandelten behandelten NN cord-015369-72cjogxz 1698 6 Fällen Fällen NNP cord-015369-72cjogxz 1698 7 trat trat NNP cord-015369-72cjogxz 1698 8 eine eine FW cord-015369-72cjogxz 1698 9 schwerwiegende schwerwiegende JJ cord-015369-72cjogxz 1698 10 Komplikation Komplikation NNP cord-015369-72cjogxz 1699 1 ( ( -LRB- cord-015369-72cjogxz 1699 2 z. z. NNP cord-015369-72cjogxz 1699 3 B. B. NNP cord-015369-72cjogxz 1699 4 tiefe tiefe IN cord-015369-72cjogxz 1699 5 Beinvenenthrombose Beinvenenthrombose NNP cord-015369-72cjogxz 1699 6 ) ) -RRB- cord-015369-72cjogxz 1699 7 auf auf NNP cord-015369-72cjogxz 1699 8 . . . cord-015369-72cjogxz 1700 1 In in IN cord-015369-72cjogxz 1700 2 6 6 CD cord-015369-72cjogxz 1700 3 % % NN cord-015369-72cjogxz 1700 4 bestanden bestanden NNP cord-015369-72cjogxz 1700 5 i -PRON- PRP cord-015369-72cjogxz 1700 6 m be VBP cord-015369-72cjogxz 1701 1 Bereich Bereich NNP cord-015369-72cjogxz 1701 2 der der NNP cord-015369-72cjogxz 1701 3 behandelten behandelten NNP cord-015369-72cjogxz 1701 4 Stammvenen Stammvenen NNP cord-015369-72cjogxz 1701 5 nach nach NNP cord-015369-72cjogxz 1701 6 6 6 CD cord-015369-72cjogxz 1702 1 Monaten Monaten NNP cord-015369-72cjogxz 1702 2 Parästhesien Parästhesien NNP cord-015369-72cjogxz 1702 3 . . . cord-015369-72cjogxz 1703 1 In in IN cord-015369-72cjogxz 1703 2 der der NNP cord-015369-72cjogxz 1703 3 Bare Bare NNP cord-015369-72cjogxz 1703 4 - - HYPH cord-015369-72cjogxz 1703 5 Fiber Fiber NNP cord-015369-72cjogxz 1703 6 Gruppe Gruppe NNP cord-015369-72cjogxz 1703 7 bestand bestand NNP cord-015369-72cjogxz 1703 8 eine eine JJ cord-015369-72cjogxz 1703 9 Tendenz Tendenz NNP cord-015369-72cjogxz 1703 10 zu zu NNP cord-015369-72cjogxz 1703 11 mehr mehr NNP cord-015369-72cjogxz 1703 12 Schmerzhaftigkeit Schmerzhaftigkeit NNP cord-015369-72cjogxz 1703 13 , , , cord-015369-72cjogxz 1703 14 bei bei NNP cord-015369-72cjogxz 1703 15 ebenfalls ebenfalls NNP cord-015369-72cjogxz 1703 16 100 100 CD cord-015369-72cjogxz 1703 17 % % NN cord-015369-72cjogxz 1703 18 iger iger NNP cord-015369-72cjogxz 1703 19 Verschlussrate Verschlussrate NNP cord-015369-72cjogxz 1703 20 und und RB cord-015369-72cjogxz 1703 21 ansonsten ansonsten NNP cord-015369-72cjogxz 1704 1 vergleichbarem vergleichbarem NNP cord-015369-72cjogxz 1704 2 Outcome Outcome NNP cord-015369-72cjogxz 1704 3 . . . cord-015369-72cjogxz 1705 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1705 2 . . . cord-015369-72cjogxz 1706 1 Zusammenfassend Zusammenfassend NNP cord-015369-72cjogxz 1706 2 lässt lässt NNP cord-015369-72cjogxz 1707 1 sich sich NNP cord-015369-72cjogxz 1707 2 anhand anhand NNP cord-015369-72cjogxz 1708 1 der der NNP cord-015369-72cjogxz 1708 2 hier hier NNP cord-015369-72cjogxz 1709 1 vorliegenden vorliegenden NNP cord-015369-72cjogxz 1709 2 Studie Studie NNP cord-015369-72cjogxz 1709 3 zeigen zeigen NNP cord-015369-72cjogxz 1709 4 , , , cord-015369-72cjogxz 1709 5 dass dass NNP cord-015369-72cjogxz 1709 6 die die VBP cord-015369-72cjogxz 1709 7 Therapie Therapie NNP cord-015369-72cjogxz 1709 8 von von NNP cord-015369-72cjogxz 1709 9 VSM VSM NNP cord-015369-72cjogxz 1709 10 mittels mittels NNP cord-015369-72cjogxz 1709 11 ELT ELT NNP cord-015369-72cjogxz 1709 12 mit mit NNP cord-015369-72cjogxz 1709 13 1470-nm 1470-nm CD cord-015369-72cjogxz 1709 14 - - HYPH cord-015369-72cjogxz 1709 15 Diodenlaser Diodenlaser NNP cord-015369-72cjogxz 1710 1 und und NNP cord-015369-72cjogxz 1711 1 Radialfaser Radialfaser NNP cord-015369-72cjogxz 1711 2 eine eine NNP cord-015369-72cjogxz 1712 1 sowohl sowohl NNP cord-015369-72cjogxz 1712 2 minimalinvasive minimalinvasive NNP cord-015369-72cjogxz 1712 3 als als NNP cord-015369-72cjogxz 1712 4 auch auch NNP cord-015369-72cjogxz 1712 5 sichere sichere NNP cord-015369-72cjogxz 1712 6 und und NNP cord-015369-72cjogxz 1712 7 effiziente effiziente NNP cord-015369-72cjogxz 1712 8 Therapieoption Therapieoption NNP cord-015369-72cjogxz 1712 9 darstellt darstellt NNP cord-015369-72cjogxz 1712 10 und und NNP cord-015369-72cjogxz 1712 11 eine eine NNP cord-015369-72cjogxz 1712 12 hohe hohe NNP cord-015369-72cjogxz 1712 13 frühzeitige frühzeitige VBN cord-015369-72cjogxz 1712 14 Erfolgsrate Erfolgsrate NNP cord-015369-72cjogxz 1712 15 bei bei NNP cord-015369-72cjogxz 1712 16 niedrigem niedrigem NNP cord-015369-72cjogxz 1712 17 Schmerzniveau Schmerzniveau NNP cord-015369-72cjogxz 1712 18 aufweist aufweist NN cord-015369-72cjogxz 1712 19 . . . cord-015369-72cjogxz 1713 1 In in IN cord-015369-72cjogxz 1713 2 weiteren weiteren NNP cord-015369-72cjogxz 1713 3 Studien Studien NNP cord-015369-72cjogxz 1713 4 muss muss VB cord-015369-72cjogxz 1713 5 geprueft geprueft NNP cord-015369-72cjogxz 1713 6 werden werden NNP cord-015369-72cjogxz 1713 7 , , , cord-015369-72cjogxz 1713 8 ob ob NNP cord-015369-72cjogxz 1713 9 aehnlich aehnlich VBD cord-015369-72cjogxz 1713 10 gute gute NNP cord-015369-72cjogxz 1713 11 Resultate Resultate NNP cord-015369-72cjogxz 1713 12 auch auch NNP cord-015369-72cjogxz 1713 13 bei bei NNP cord-015369-72cjogxz 1713 14 weiterer weiterer NNP cord-015369-72cjogxz 1713 15 Absenkung Absenkung NNP cord-015369-72cjogxz 1713 16 des des FW cord-015369-72cjogxz 1713 17 Energienivaus Energienivaus NNP cord-015369-72cjogxz 1713 18 zu zu NNP cord-015369-72cjogxz 1713 19 erreichen erreichen NNP cord-015369-72cjogxz 1713 20 sind sind NNP cord-015369-72cjogxz 1713 21 . . . cord-015369-72cjogxz 1714 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1714 2 . . . cord-015369-72cjogxz 1715 1 Es Es NNP cord-015369-72cjogxz 1715 2 gab gab NN cord-015369-72cjogxz 1716 1 keine keine NNP cord-015369-72cjogxz 1716 2 signifikanten signifikanten NNP cord-015369-72cjogxz 1716 3 Unterschiede Unterschiede NNP cord-015369-72cjogxz 1716 4 bezüglich bezüglich NNP cord-015369-72cjogxz 1716 5 Geschlecht Geschlecht NNP cord-015369-72cjogxz 1716 6 , , , cord-015369-72cjogxz 1716 7 Alter Alter NNP cord-015369-72cjogxz 1716 8 , , , cord-015369-72cjogxz 1716 9 CEAP CEAP NNP cord-015369-72cjogxz 1716 10 Stadium Stadium NNP cord-015369-72cjogxz 1716 11 , , , cord-015369-72cjogxz 1716 12 BMI BMI NNP cord-015369-72cjogxz 1716 13 oder oder NNP cord-015369-72cjogxz 1716 14 Venendurchmesser Venendurchmesser NNP cord-015369-72cjogxz 1716 15 in in IN cord-015369-72cjogxz 1716 16 den den JJ cord-015369-72cjogxz 1716 17 beiden beiden JJ cord-015369-72cjogxz 1716 18 Gruppen Gruppen NNP cord-015369-72cjogxz 1716 19 . . . cord-015369-72cjogxz 1717 1 In in IN cord-015369-72cjogxz 1717 2 beiden beiden JJ cord-015369-72cjogxz 1717 3 Gruppen Gruppen NNP cord-015369-72cjogxz 1717 4 wurden wurden VBD cord-015369-72cjogxz 1717 5 vergleichbare vergleichbare NNP cord-015369-72cjogxz 1717 6 Mengen Mengen NNP cord-015369-72cjogxz 1717 7 an an DT cord-015369-72cjogxz 1717 8 TLA TLA NNP cord-015369-72cjogxz 1717 9 verwendet verwendet NNP cord-015369-72cjogxz 1717 10 . . . cord-015369-72cjogxz 1718 1 In in IN cord-015369-72cjogxz 1718 2 Gruppe Gruppe NNP cord-015369-72cjogxz 1718 3 A A NNP cord-015369-72cjogxz 1718 4 lag lag NN cord-015369-72cjogxz 1718 5 die die NN cord-015369-72cjogxz 1718 6 mittlere mittlere NN cord-015369-72cjogxz 1718 7 EFE EFE NNP cord-015369-72cjogxz 1718 8 ( ( -LRB- cord-015369-72cjogxz 1718 9 endovenous endovenous JJ cord-015369-72cjogxz 1718 10 fluence fluence NNP cord-015369-72cjogxz 1718 11 equivalent equivalent NN cord-015369-72cjogxz 1718 12 ) ) -RRB- cord-015369-72cjogxz 1719 1 bei bei NNP cord-015369-72cjogxz 1719 2 31 31 CD cord-015369-72cjogxz 1720 1 J J NNP cord-015369-72cjogxz 1720 2 / / SYM cord-015369-72cjogxz 1720 3 cm cm NNP cord-015369-72cjogxz 1720 4 2 2 CD cord-015369-72cjogxz 1721 1 und und NNP cord-015369-72cjogxz 1721 2 in in IN cord-015369-72cjogxz 1721 3 der der NNP cord-015369-72cjogxz 1721 4 Gruppe Gruppe NNP cord-015369-72cjogxz 1721 5 B B NNP cord-015369-72cjogxz 1721 6 bei bei NNP cord-015369-72cjogxz 1721 7 40 40 CD cord-015369-72cjogxz 1721 8 J J NNP cord-015369-72cjogxz 1721 9 / / SYM cord-015369-72cjogxz 1721 10 cm cm NNP cord-015369-72cjogxz 1721 11 2 2 CD cord-015369-72cjogxz 1721 12 . . . cord-015369-72cjogxz 1722 1 In in IN cord-015369-72cjogxz 1722 2 beiden beiden JJ cord-015369-72cjogxz 1722 3 Gruppen Gruppen NNP cord-015369-72cjogxz 1722 4 lag lag VBP cord-015369-72cjogxz 1722 5 die die VB cord-015369-72cjogxz 1722 6 Verschlussrate Verschlussrate NNP cord-015369-72cjogxz 1722 7 bei bei NNP cord-015369-72cjogxz 1722 8 100 100 CD cord-015369-72cjogxz 1722 9 % % NN cord-015369-72cjogxz 1722 10 . . . cord-015369-72cjogxz 1723 1 Die die VB cord-015369-72cjogxz 1723 2 Durchmesserreduktion Durchmesserreduktion NNP cord-015369-72cjogxz 1723 3 der der NNP cord-015369-72cjogxz 1723 4 VSM VSM NNP cord-015369-72cjogxz 1723 5 3 3 CD cord-015369-72cjogxz 1723 6 cm cm NNP cord-015369-72cjogxz 1723 7 distal distal JJ cord-015369-72cjogxz 1723 8 der der NNP cord-015369-72cjogxz 1723 9 sapheno sapheno NNP cord-015369-72cjogxz 1723 10 - - HYPH cord-015369-72cjogxz 1723 11 femoralen femoralen VBN cord-015369-72cjogxz 1723 12 Crosse Crosse NNP cord-015369-72cjogxz 1723 13 lag lag VBP cord-015369-72cjogxz 1723 14 bei bei NNP cord-015369-72cjogxz 1723 15 1.1 1.1 CD cord-015369-72cjogxz 1723 16 auf auf NNP cord-015369-72cjogxz 1723 17 0.6 0.6 CD cord-015369-72cjogxz 1723 18 cm cm NN cord-015369-72cjogxz 1723 19 nach nach NNP cord-015369-72cjogxz 1723 20 1 1 CD cord-015369-72cjogxz 1723 21 Monat Monat NNP cord-015369-72cjogxz 1723 22 und und IN cord-015369-72cjogxz 1723 23 0,3 0,3 CD cord-015369-72cjogxz 1723 24 cm cm NN cord-015369-72cjogxz 1723 25 nach nach NNP cord-015369-72cjogxz 1723 26 5 5 CD cord-015369-72cjogxz 1723 27 Monaten Monaten NNP cord-015369-72cjogxz 1723 28 . . . cord-015369-72cjogxz 1724 1 Das Das NNP cord-015369-72cjogxz 1724 2 C C NNP cord-015369-72cjogxz 1724 3 der der NNP cord-015369-72cjogxz 1724 4 CEAP CEAP NNP cord-015369-72cjogxz 1724 5 Klassifikation Klassifikation NNP cord-015369-72cjogxz 1724 6 verbesserte verbesserte NNS cord-015369-72cjogxz 1724 7 sich sich NNP cord-015369-72cjogxz 1724 8 signifikant signifikant NNP cord-015369-72cjogxz 1724 9 in in IN cord-015369-72cjogxz 1724 10 beiden beiden JJ cord-015369-72cjogxz 1724 11 Gruppen Gruppen NNP cord-015369-72cjogxz 1724 12 . . . cord-015369-72cjogxz 1725 1 Gruppe Gruppe NNP cord-015369-72cjogxz 1725 2 A a DT cord-015369-72cjogxz 1725 3 verwendete verwendete NN cord-015369-72cjogxz 1725 4 signifikant signifikant NN cord-015369-72cjogxz 1725 5 weniger weniger NNP cord-015369-72cjogxz 1725 6 Schmerztabletten Schmerztabletten NNP cord-015369-72cjogxz 1725 7 , , , cord-015369-72cjogxz 1725 8 an an DT cord-015369-72cjogxz 1725 9 weniger weniger NNP cord-015369-72cjogxz 1725 10 Tagen Tagen NNP cord-015369-72cjogxz 1725 11 . . . cord-015369-72cjogxz 1726 1 In in IN cord-015369-72cjogxz 1726 2 Gruppe Gruppe NNP cord-015369-72cjogxz 1726 3 A A NNP cord-015369-72cjogxz 1726 4 gab gab NN cord-015369-72cjogxz 1726 5 es es XX cord-015369-72cjogxz 1726 6 außerdem außerdem XX cord-015369-72cjogxz 1726 7 einen einen NNP cord-015369-72cjogxz 1726 8 Trend Trend NNP cord-015369-72cjogxz 1726 9 zu zu NNP cord-015369-72cjogxz 1726 10 weniger weniger NNS cord-015369-72cjogxz 1726 11 postinterventionellen postinterventionellen NNP cord-015369-72cjogxz 1726 12 Schmerzen Schmerzen NNP cord-015369-72cjogxz 1726 13 . . . cord-015369-72cjogxz 1727 1 Ecchymosen Ecchymosen NNP cord-015369-72cjogxz 1727 2 waren waren NNP cord-015369-72cjogxz 1727 3 in in IN cord-015369-72cjogxz 1727 4 beiden beiden NNP cord-015369-72cjogxz 1728 1 Gruppen Gruppen NNP cord-015369-72cjogxz 1728 2 selten selten NNP cord-015369-72cjogxz 1728 3 ( ( -LRB- cord-015369-72cjogxz 1728 4 17 17 CD cord-015369-72cjogxz 1728 5 % % NN cord-015369-72cjogxz 1728 6 in in IN cord-015369-72cjogxz 1728 7 Gruppe Gruppe NNP cord-015369-72cjogxz 1728 8 A A NNP cord-015369-72cjogxz 1728 9 , , , cord-015369-72cjogxz 1728 10 33 33 CD cord-015369-72cjogxz 1728 11 % % NN cord-015369-72cjogxz 1728 12 in in IN cord-015369-72cjogxz 1728 13 Gruppe Gruppe NNP cord-015369-72cjogxz 1728 14 B B NNP cord-015369-72cjogxz 1728 15 ) ) -RRB- cord-015369-72cjogxz 1728 16 . . . cord-015369-72cjogxz 1729 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1729 2 . . . cord-015369-72cjogxz 1730 1 Die die VB cord-015369-72cjogxz 1730 2 Laserpower Laserpower NNP cord-015369-72cjogxz 1730 3 beeinflusste beeinflusste NN cord-015369-72cjogxz 1731 1 nicht nicht NNP cord-015369-72cjogxz 1731 2 die die VBP cord-015369-72cjogxz 1731 3 Verschlussrate Verschlussrate NNP cord-015369-72cjogxz 1731 4 bei bei NNP cord-015369-72cjogxz 1731 5 der der NNP cord-015369-72cjogxz 1731 6 verwendeten verwendeten NNP cord-015369-72cjogxz 1731 7 hohen hohen NNP cord-015369-72cjogxz 1731 8 EFE EFE NNP cord-015369-72cjogxz 1731 9 in in IN cord-015369-72cjogxz 1731 10 beiden beiden JJ cord-015369-72cjogxz 1731 11 Gruppen Gruppen NNP cord-015369-72cjogxz 1731 12 . . . cord-015369-72cjogxz 1732 1 In in IN cord-015369-72cjogxz 1732 2 beiden beiden JJ cord-015369-72cjogxz 1732 3 Gruppen Gruppen NNP cord-015369-72cjogxz 1732 4 waren waren NNP cord-015369-72cjogxz 1732 5 Ecchymosen Ecchymosen NNP cord-015369-72cjogxz 1732 6 und und IN cord-015369-72cjogxz 1732 7 Schmerzen Schmerzen NNP cord-015369-72cjogxz 1732 8 seltener seltener NN cord-015369-72cjogxz 1732 9 als als NN cord-015369-72cjogxz 1732 10 in in IN cord-015369-72cjogxz 1732 11 Studien Studien NNP cord-015369-72cjogxz 1732 12 mit mit NNP cord-015369-72cjogxz 1732 13 810 810 CD cord-015369-72cjogxz 1732 14 - - SYM cord-015369-72cjogxz 1732 15 980 980 CD cord-015369-72cjogxz 1732 16 nm nm NN cord-015369-72cjogxz 1732 17 . . . cord-015369-72cjogxz 1733 1 10 10 CD cord-015369-72cjogxz 1734 1 W W NNP cord-015369-72cjogxz 1734 2 Laserpower Laserpower NNP cord-015369-72cjogxz 1734 3 reduzierte reduzierte NN cord-015369-72cjogxz 1734 4 signifikant signifikant NN cord-015369-72cjogxz 1734 5 die die VB cord-015369-72cjogxz 1734 6 Schmerzmitteleinnahme Schmerzmitteleinnahme NNP cord-015369-72cjogxz 1734 7 . . . cord-015369-72cjogxz 1735 1 In in IN cord-015369-72cjogxz 1735 2 beiden beiden JJ cord-015369-72cjogxz 1735 3 Gruppen Gruppen NNP cord-015369-72cjogxz 1735 4 fanden fanden NNP cord-015369-72cjogxz 1735 5 sich sich NNP cord-015369-72cjogxz 1735 6 gute gute NNP cord-015369-72cjogxz 1735 7 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1735 8 , , , cord-015369-72cjogxz 1735 9 es es NNP cord-015369-72cjogxz 1735 10 fand fand NNP cord-015369-72cjogxz 1735 11 sich sich NNP cord-015369-72cjogxz 1735 12 nur nur NNP cord-015369-72cjogxz 1735 13 ein ein NNP cord-015369-72cjogxz 1735 14 geringer geringer NN cord-015369-72cjogxz 1735 15 , , , cord-015369-72cjogxz 1735 16 kurzfristiger kurzfristiger NNP cord-015369-72cjogxz 1735 17 Vorteil Vorteil NNP cord-015369-72cjogxz 1735 18 für für NNP cord-015369-72cjogxz 1735 19 die die VBP cord-015369-72cjogxz 1735 20 Lasertherapie Lasertherapie NNP cord-015369-72cjogxz 1736 1 ( ( -LRB- cord-015369-72cjogxz 1736 2 kleinere kleinere NNP cord-015369-72cjogxz 1736 3 Hämatomfläche Hämatomfläche NNP cord-015369-72cjogxz 1736 4 ) ) -RRB- cord-015369-72cjogxz 1736 5 bei bei NNP cord-015369-72cjogxz 1736 6 i i PRP cord-015369-72cjogxz 1737 1 m m NNP cord-015369-72cjogxz 1737 2 weiteren weiteren NNP cord-015369-72cjogxz 1737 3 Verlauf Verlauf NNP cord-015369-72cjogxz 1738 1 nahezu nahezu NNP cord-015369-72cjogxz 1738 2 gleichem gleichem NNP cord-015369-72cjogxz 1738 3 Patientenkomfort Patientenkomfort NNP cord-015369-72cjogxz 1738 4 . . . cord-015369-72cjogxz 1739 1 Die die VB cord-015369-72cjogxz 1739 2 hohen hohen NNP cord-015369-72cjogxz 1739 3 Kosten Kosten NNP cord-015369-72cjogxz 1739 4 der der NNP cord-015369-72cjogxz 1739 5 Lasertherapie Lasertherapie NNP cord-015369-72cjogxz 1739 6 können können NNP cord-015369-72cjogxz 1739 7 somit somit NNP cord-015369-72cjogxz 1739 8 nur nur NNP cord-015369-72cjogxz 1739 9 schwer schwer NNP cord-015369-72cjogxz 1739 10 gerechtfertigt gerechtfertigt NNP cord-015369-72cjogxz 1739 11 werden werden NNP cord-015369-72cjogxz 1739 12 . . . cord-015369-72cjogxz 1740 1 Eine Eine NNP cord-015369-72cjogxz 1740 2 Kombination Kombination NNP cord-015369-72cjogxz 1740 3 von von NNP cord-015369-72cjogxz 1740 4 Crossektomie Crossektomie NNP cord-015369-72cjogxz 1740 5 und und IN cord-015369-72cjogxz 1740 6 Laserablation Laserablation NNP cord-015369-72cjogxz 1740 7 ist ist NNP cord-015369-72cjogxz 1740 8 eher eher NNP cord-015369-72cjogxz 1740 9 nicht nicht NNP cord-015369-72cjogxz 1740 10 sinnvoll sinnvoll NNP cord-015369-72cjogxz 1740 11 . . . cord-015369-72cjogxz 1741 1 Die die VB cord-015369-72cjogxz 1742 1 Laserablation Laserablation NNP cord-015369-72cjogxz 1742 2 kann kann NNP cord-015369-72cjogxz 1742 3 als als NNP cord-015369-72cjogxz 1742 4 minimal minimal JJ cord-015369-72cjogxz 1742 5 invasive invasive JJ cord-015369-72cjogxz 1742 6 Alternative alternative JJ cord-015369-72cjogxz 1742 7 zum zum NN cord-015369-72cjogxz 1742 8 Standardverfahren Standardverfahren NNP cord-015369-72cjogxz 1742 9 Stripping strip VBG cord-015369-72cjogxz 1742 10 nach nach NNP cord-015369-72cjogxz 1742 11 umfassender umfassender NN cord-015369-72cjogxz 1743 1 und und IN cord-015369-72cjogxz 1743 2 objektiver objektiver NNP cord-015369-72cjogxz 1743 3 Patienteninformation Patienteninformation NNP cord-015369-72cjogxz 1743 4 ( ( -LRB- cord-015369-72cjogxz 1743 5 fehlende fehlende NNP cord-015369-72cjogxz 1743 6 Langzeitergebnisse Langzeitergebnisse NNP cord-015369-72cjogxz 1743 7 , , , cord-015369-72cjogxz 1743 8 mögliches mögliches NNP cord-015369-72cjogxz 1743 9 Leistenrezidiv Leistenrezidiv NNP cord-015369-72cjogxz 1743 10 durch durch NNP cord-015369-72cjogxz 1743 11 Weglassen Weglassen NNP cord-015369-72cjogxz 1743 12 der der NNP cord-015369-72cjogxz 1743 13 Crossektomie Crossektomie NNP cord-015369-72cjogxz 1743 14 ) ) -RRB- cord-015369-72cjogxz 1743 15 angeboten angeboten VBN cord-015369-72cjogxz 1743 16 werden werden NNP cord-015369-72cjogxz 1743 17 . . . cord-015369-72cjogxz 1744 1 Endovasculäre Endovasculäre NNP cord-015369-72cjogxz 1744 2 Verfahren Verfahren NNP cord-015369-72cjogxz 1744 3 in in IN cord-015369-72cjogxz 1744 4 der der NNP cord-015369-72cjogxz 1744 5 Behandlung Behandlung NNP cord-015369-72cjogxz 1744 6 der der NNP cord-015369-72cjogxz 1744 7 Rezidivvarikositas Rezidivvarikositas NNP cord-015369-72cjogxz 1744 8 A. a. NN cord-015369-72cjogxz 1744 9 J. J. NNP cord-015369-72cjogxz 1744 10 Flor Flor NNP cord-015369-72cjogxz 1744 11 Grundlagen Grundlagen NNP cord-015369-72cjogxz 1744 12 . . . cord-015369-72cjogxz 1745 1 Das Das NNP cord-015369-72cjogxz 1745 2 Leistenrezidiv Leistenrezidiv NNP cord-015369-72cjogxz 1745 3 nach nach NNP cord-015369-72cjogxz 1745 4 Crossektomie Crossektomie NNP cord-015369-72cjogxz 1746 1 ist ist NNP cord-015369-72cjogxz 1746 2 ein ein VBP cord-015369-72cjogxz 1746 3 häufig häufig NNP cord-015369-72cjogxz 1746 4 zu zu NNP cord-015369-72cjogxz 1746 5 beobachtendes beobachtendes NNPS cord-015369-72cjogxz 1746 6 Phänomen Phänomen NNP cord-015369-72cjogxz 1746 7 und und IN cord-015369-72cjogxz 1746 8 mittels mittels NNP cord-015369-72cjogxz 1746 9 farbcodiertem farbcodiertem NNP cord-015369-72cjogxz 1747 1 Ultraschall Ultraschall NNP cord-015369-72cjogxz 1747 2 gut gut VBP cord-015369-72cjogxz 1747 3 nachzuweisen nachzuweisen NNP cord-015369-72cjogxz 1747 4 . . . cord-015369-72cjogxz 1748 1 Als Als NNP cord-015369-72cjogxz 1748 2 Ursache Ursache NNP cord-015369-72cjogxz 1748 3 sieht sieht NNP cord-015369-72cjogxz 1748 4 man man NN cord-015369-72cjogxz 1749 1 eine eine NNP cord-015369-72cjogxz 1749 2 Neovaskularisation Neovaskularisation NNP cord-015369-72cjogxz 1749 3 von von NNP cord-015369-72cjogxz 1749 4 Gefäßstümpfen Gefäßstümpfen NNP cord-015369-72cjogxz 1749 5 ausgehend ausgehend NNP cord-015369-72cjogxz 1749 6 , , , cord-015369-72cjogxz 1749 7 welche welche NNP cord-015369-72cjogxz 1749 8 in in IN cord-015369-72cjogxz 1749 9 der der NNP cord-015369-72cjogxz 1749 10 Literatur Literatur NNP cord-015369-72cjogxz 1749 11 mit mit NNP cord-015369-72cjogxz 1749 12 einer einer NNP cord-015369-72cjogxz 1750 1 Häufigkeit Häufigkeit NNP cord-015369-72cjogxz 1750 2 bis bis NNP cord-015369-72cjogxz 1750 3 zu zu NNP cord-015369-72cjogxz 1750 4 70 70 CD cord-015369-72cjogxz 1750 5 % % NN cord-015369-72cjogxz 1750 6 angegeben angegeben NNP cord-015369-72cjogxz 1750 7 wird wird NNP cord-015369-72cjogxz 1750 8 . . . cord-015369-72cjogxz 1751 1 In in IN cord-015369-72cjogxz 1751 2 vielen vielen NNP cord-015369-72cjogxz 1751 3 Fällen Fällen NNP cord-015369-72cjogxz 1751 4 zeigen zeigen NNP cord-015369-72cjogxz 1751 5 sich sich NNP cord-015369-72cjogxz 1751 6 i -PRON- PRP cord-015369-72cjogxz 1751 7 m be VBP cord-015369-72cjogxz 1751 8 Ultraschall Ultraschall NNP cord-015369-72cjogxz 1751 9 Reanschlüsse Reanschlüsse NNP cord-015369-72cjogxz 1752 1 an an DT cord-015369-72cjogxz 1752 2 intrafaszial intrafaszial JJ cord-015369-72cjogxz 1752 3 gelegene gelegene NN cord-015369-72cjogxz 1752 4 Stammgefäße Stammgefäße NNP cord-015369-72cjogxz 1752 5 . . . cord-015369-72cjogxz 1753 1 Methodik Methodik NNP cord-015369-72cjogxz 1753 2 . . . cord-015369-72cjogxz 1754 1 Es Es NNP cord-015369-72cjogxz 1754 2 erfolgt erfolgt NNP cord-015369-72cjogxz 1755 1 eine eine NNP cord-015369-72cjogxz 1755 2 eingehende eingehende NNP cord-015369-72cjogxz 1755 3 Evaluierung Evaluierung NNP cord-015369-72cjogxz 1755 4 mittels mittels NNP cord-015369-72cjogxz 1755 5 Farbultraschall Farbultraschall NNP cord-015369-72cjogxz 1755 6 . . . cord-015369-72cjogxz 1756 1 Finden Finden NNP cord-015369-72cjogxz 1756 2 sich sich NNP cord-015369-72cjogxz 1756 3 insuffiziente insuffiziente NNP cord-015369-72cjogxz 1756 4 intrafaszial intrafaszial NN cord-015369-72cjogxz 1756 5 gelegene gelegene NNP cord-015369-72cjogxz 1756 6 Stammgefäße Stammgefäße NNP cord-015369-72cjogxz 1756 7 , , , cord-015369-72cjogxz 1756 8 erfolgt erfolgt UH cord-015369-72cjogxz 1756 9 die die VBP cord-015369-72cjogxz 1756 10 Entscheidung Entscheidung NNP cord-015369-72cjogxz 1756 11 , , , cord-015369-72cjogxz 1756 12 solch solch NNP cord-015369-72cjogxz 1756 13 ein ein NNP cord-015369-72cjogxz 1756 14 Gefäß Gefäß NNP cord-015369-72cjogxz 1756 15 mittels mittels NNP cord-015369-72cjogxz 1756 16 ELVES ELVES NNP cord-015369-72cjogxz 1756 17 - - HYPH cord-015369-72cjogxz 1756 18 Verfahren Verfahren NNP cord-015369-72cjogxz 1756 19 ( ( -LRB- cord-015369-72cjogxz 1756 20 1470 1470 CD cord-015369-72cjogxz 1756 21 nm nm NNP cord-015369-72cjogxz 1756 22 Diodenlaser Diodenlaser NNP cord-015369-72cjogxz 1756 23 , , , cord-015369-72cjogxz 1756 24 in in IN cord-015369-72cjogxz 1756 25 selektierten selektierten NNP cord-015369-72cjogxz 1756 26 Fällen Fällen NNP cord-015369-72cjogxz 1756 27 mit mit NNP cord-015369-72cjogxz 1756 28 Radialsonde Radialsonde NNP cord-015369-72cjogxz 1756 29 ) ) -RRB- cord-015369-72cjogxz 1757 1 oder oder NNP cord-015369-72cjogxz 1757 2 mittels mittels NNP cord-015369-72cjogxz 1757 3 farbduplexgezielter farbduplexgezielter NNP cord-015369-72cjogxz 1757 4 Schaumverödung Schaumverödung NNP cord-015369-72cjogxz 1757 5 zu zu NNP cord-015369-72cjogxz 1757 6 behandeln behandeln NNP cord-015369-72cjogxz 1757 7 . . . cord-015369-72cjogxz 1758 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1758 2 . . . cord-015369-72cjogxz 1759 1 Die die VB cord-015369-72cjogxz 1759 2 Endolaser Endolaser NNP cord-015369-72cjogxz 1759 3 - - HYPH cord-015369-72cjogxz 1759 4 Obliteration obliteration NN cord-015369-72cjogxz 1759 5 mittels mittel NNS cord-015369-72cjogxz 1759 6 ELVES ELVES NNP cord-015369-72cjogxz 1759 7 - - HYPH cord-015369-72cjogxz 1759 8 Verfahren Verfahren NNP cord-015369-72cjogxz 1760 1 fü fü IN cord-015369-72cjogxz 1760 2 hrt hrt NNP cord-015369-72cjogxz 1760 3 in in IN cord-015369-72cjogxz 1760 4 mehr mehr NNP cord-015369-72cjogxz 1760 5 als als NNP cord-015369-72cjogxz 1760 6 95 95 CD cord-015369-72cjogxz 1760 7 % % NN cord-015369-72cjogxz 1761 1 zu zu NNP cord-015369-72cjogxz 1761 2 einem einem NNP cord-015369-72cjogxz 1761 3 primären primären NNP cord-015369-72cjogxz 1761 4 Komplettverschluss Komplettverschluss NNP cord-015369-72cjogxz 1761 5 des des NNP cord-015369-72cjogxz 1761 6 insuffizienten insuffizienten NNP cord-015369-72cjogxz 1761 7 Stammgefäßes Stammgefäßes NNP cord-015369-72cjogxz 1761 8 . . . cord-015369-72cjogxz 1762 1 In in IN cord-015369-72cjogxz 1762 2 der der NNP cord-015369-72cjogxz 1762 3 Ultraschallkontrolle Ultraschallkontrolle NNP cord-015369-72cjogxz 1762 4 zeigt zeigt NNP cord-015369-72cjogxz 1762 5 sich sich NNP cord-015369-72cjogxz 1762 6 das das NNP cord-015369-72cjogxz 1762 7 kontrahierte kontrahierte NNP cord-015369-72cjogxz 1762 8 Gefäß Gefäß NNP cord-015369-72cjogxz 1762 9 , , , cord-015369-72cjogxz 1762 10 welches welches NNP cord-015369-72cjogxz 1762 11 sich sich NNP cord-015369-72cjogxz 1762 12 in in IN cord-015369-72cjogxz 1762 13 weiterer weiterer NNP cord-015369-72cjogxz 1762 14 Folge Folge NNP cord-015369-72cjogxz 1762 15 zu zu NNP cord-015369-72cjogxz 1762 16 einem einem NNP cord-015369-72cjogxz 1762 17 fibrotischen fibrotischen NNP cord-015369-72cjogxz 1762 18 Strang Strang NNP cord-015369-72cjogxz 1762 19 umwandelt umwandelt NNP cord-015369-72cjogxz 1762 20 , , , cord-015369-72cjogxz 1762 21 um um UH cord-015369-72cjogxz 1762 22 schlussendlich schlussendlich NNP cord-015369-72cjogxz 1762 23 komplett komplett NNP cord-015369-72cjogxz 1762 24 zu zu NNP cord-015369-72cjogxz 1762 25 verschwinden verschwinden NNP cord-015369-72cjogxz 1762 26 . . . cord-015369-72cjogxz 1763 1 Die die VB cord-015369-72cjogxz 1763 2 farbduplexgezielte farbduplexgezielte NNP cord-015369-72cjogxz 1763 3 Schaumverödung Schaumverödung NNP cord-015369-72cjogxz 1763 4 zeigt zeigt NNP cord-015369-72cjogxz 1763 5 in in IN cord-015369-72cjogxz 1763 6 vielen vielen NNP cord-015369-72cjogxz 1763 7 Fällen Fällen NNP cord-015369-72cjogxz 1763 8 Rekanalisationen Rekanalisationen NNP cord-015369-72cjogxz 1763 9 , , , cord-015369-72cjogxz 1763 10 zum zum NNP cord-015369-72cjogxz 1763 11 Teil Teil NNP cord-015369-72cjogxz 1763 12 mit mit JJ cord-015369-72cjogxz 1763 13 Reflux reflux NN cord-015369-72cjogxz 1763 14 . . . cord-015369-72cjogxz 1764 1 In in IN cord-015369-72cjogxz 1764 2 vielen vielen JJ cord-015369-72cjogxz 1764 3 Fällen Fällen NNP cord-015369-72cjogxz 1764 4 muss muss VBP cord-015369-72cjogxz 1764 5 die die VB cord-015369-72cjogxz 1764 6 farbduplexgezielte farbduplexgezielte JJ cord-015369-72cjogxz 1764 7 Schaumverödung Schaumverödung NNP cord-015369-72cjogxz 1765 1 mehrfach mehrfach NNP cord-015369-72cjogxz 1765 2 wiederholt wiederholt NNP cord-015369-72cjogxz 1765 3 werden werden NNP cord-015369-72cjogxz 1765 4 . . . cord-015369-72cjogxz 1766 1 Auffallend Auffallend NNP cord-015369-72cjogxz 1766 2 ist ist NNP cord-015369-72cjogxz 1766 3 , , , cord-015369-72cjogxz 1766 4 dass dass NNP cord-015369-72cjogxz 1766 5 sich sich NNP cord-015369-72cjogxz 1766 6 der der NNP cord-015369-72cjogxz 1767 1 Venendurchmesser Venendurchmesser NNP cord-015369-72cjogxz 1767 2 i -PRON- PRP cord-015369-72cjogxz 1767 3 m be VBP cord-015369-72cjogxz 1767 4 Zuge Zuge NNP cord-015369-72cjogxz 1767 5 der der NNP cord-015369-72cjogxz 1767 6 Behandlung Behandlung NNP cord-015369-72cjogxz 1767 7 mittels mittels NNP cord-015369-72cjogxz 1767 8 Schaum Schaum NNP cord-015369-72cjogxz 1767 9 deutlich deutlich NNP cord-015369-72cjogxz 1767 10 weniger weniger NNP cord-015369-72cjogxz 1767 11 reduziert reduziert NNP cord-015369-72cjogxz 1767 12 als als NNP cord-015369-72cjogxz 1767 13 beim beim NNP cord-015369-72cjogxz 1767 14 Endolaserverfahren Endolaserverfahren NNP cord-015369-72cjogxz 1767 15 . . . cord-015369-72cjogxz 1768 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1768 2 . . . cord-015369-72cjogxz 1769 1 Endolaser Endolaser NNP cord-015369-72cjogxz 1769 2 und und IN cord-015369-72cjogxz 1769 3 farbduplexgezielte farbduplexgezielte NNP cord-015369-72cjogxz 1770 1 Schaumverödung Schaumverödung NNP cord-015369-72cjogxz 1770 2 eignen eignen NNP cord-015369-72cjogxz 1770 3 sich sich NNP cord-015369-72cjogxz 1770 4 gut gut NNP cord-015369-72cjogxz 1771 1 zur zur NNP cord-015369-72cjogxz 1771 2 Behandlung Behandlung NNP cord-015369-72cjogxz 1771 3 insuffizienter insuffizienter NN cord-015369-72cjogxz 1772 1 Stammgefäße Stammgefäße NNP cord-015369-72cjogxz 1772 2 bei bei NNP cord-015369-72cjogxz 1772 3 der der NNP cord-015369-72cjogxz 1772 4 Behandlung Behandlung NNP cord-015369-72cjogxz 1772 5 der der NNP cord-015369-72cjogxz 1772 6 Rezidivvarikositas Rezidivvarikositas NNP cord-015369-72cjogxz 1772 7 . . . cord-015369-72cjogxz 1773 1 Sie Sie NNP cord-015369-72cjogxz 1773 2 können können NNP cord-015369-72cjogxz 1773 3 in in IN cord-015369-72cjogxz 1773 4 vielen vielen NNP cord-015369-72cjogxz 1773 5 Fällen Fällen NNP cord-015369-72cjogxz 1773 6 Recrossektomien Recrossektomien NNP cord-015369-72cjogxz 1773 7 und und IN cord-015369-72cjogxz 1773 8 andere andere NN cord-015369-72cjogxz 1774 1 chirurgische chirurgische NNP cord-015369-72cjogxz 1774 2 Zugänge Zugänge NNP cord-015369-72cjogxz 1774 3 ersparen ersparen VBZ cord-015369-72cjogxz 1774 4 und und IN cord-015369-72cjogxz 1775 1 sollten sollten NNP cord-015369-72cjogxz 1775 2 somit somit NNP cord-015369-72cjogxz 1775 3 gerade gerade NNP cord-015369-72cjogxz 1775 4 bei bei NNP cord-015369-72cjogxz 1775 5 der der NNP cord-015369-72cjogxz 1775 6 Behandlung Behandlung NNP cord-015369-72cjogxz 1775 7 der der NNP cord-015369-72cjogxz 1775 8 Rezidivvarikositas Rezidivvarikositas NNP cord-015369-72cjogxz 1775 9 nicht nicht NNP cord-015369-72cjogxz 1775 10 als als NNP cord-015369-72cjogxz 1775 11 ' ' `` cord-015369-72cjogxz 1775 12 Lifestylephänomen Lifestylephänomen NNP cord-015369-72cjogxz 1775 13 ' ' POS cord-015369-72cjogxz 1775 14 abgetan abgetan NNP cord-015369-72cjogxz 1775 15 werden werden NNP cord-015369-72cjogxz 1775 16 . . . cord-015369-72cjogxz 1776 1 Insbesondere Insbesondere NNP cord-015369-72cjogxz 1776 2 die die VBP cord-015369-72cjogxz 1776 3 Endolaserbehandlung Endolaserbehandlung NNP cord-015369-72cjogxz 1776 4 kann kann NNP cord-015369-72cjogxz 1776 5 intrafaszial intrafaszial NNP cord-015369-72cjogxz 1776 6 gelegene gelegene NNP cord-015369-72cjogxz 1776 7 Neovarizen Neovarizen NNP cord-015369-72cjogxz 1776 8 suffizient suffizient NN cord-015369-72cjogxz 1776 9 in in IN cord-015369-72cjogxz 1776 10 einer einer NNP cord-015369-72cjogxz 1776 11 Sitzung Sitzung NNP cord-015369-72cjogxz 1776 12 schnittfrei schnittfrei NN cord-015369-72cjogxz 1776 13 verschließen verschließen NNP cord-015369-72cjogxz 1776 14 . . . cord-015369-72cjogxz 1777 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1777 2 . . . cord-015369-72cjogxz 1778 1 Auf Auf NNP cord-015369-72cjogxz 1778 2 einer einer NNP cord-015369-72cjogxz 1778 3 Skala Skala NNP cord-015369-72cjogxz 1778 4 von von NNP cord-015369-72cjogxz 1778 5 1 1 CD cord-015369-72cjogxz 1778 6 - - SYM cord-015369-72cjogxz 1778 7 5 5 CD cord-015369-72cjogxz 1779 1 ( ( -LRB- cord-015369-72cjogxz 1779 2 1-sehr 1-sehr CD cord-015369-72cjogxz 1779 3 gut gut NN cord-015369-72cjogxz 1779 4 , , , cord-015369-72cjogxz 1779 5 5-nicht 5-nicht CD cord-015369-72cjogxz 1779 6 genügend genügend NNP cord-015369-72cjogxz 1779 7 ) ) -RRB- cord-015369-72cjogxz 1779 8 ergaben ergaben NNP cord-015369-72cjogxz 1779 9 sich sich NNP cord-015369-72cjogxz 1779 10 durchnschnittliche durchnschnittliche NNP cord-015369-72cjogxz 1779 11 Werte Werte NNP cord-015369-72cjogxz 1779 12 von von NNP cord-015369-72cjogxz 1779 13 1.2 1.2 CD cord-015369-72cjogxz 1780 1 ( ( -LRB- cord-015369-72cjogxz 1780 2 Trokarplatzierung Trokarplatzierung NNP cord-015369-72cjogxz 1780 3 ) ) -RRB- cord-015369-72cjogxz 1780 4 , , , cord-015369-72cjogxz 1780 5 1,2 1,2 CD cord-015369-72cjogxz 1780 6 ( ( -LRB- cord-015369-72cjogxz 1780 7 Nadelplatzierung Nadelplatzierung NNP cord-015369-72cjogxz 1780 8 ) ) -RRB- cord-015369-72cjogxz 1780 9 , , , cord-015369-72cjogxz 1780 10 1 1 CD cord-015369-72cjogxz 1780 11 ( ( -LRB- cord-015369-72cjogxz 1780 12 Führungsdrahteinlage Führungsdrahteinlage NNP cord-015369-72cjogxz 1780 13 ) ) -RRB- cord-015369-72cjogxz 1780 14 , , , cord-015369-72cjogxz 1780 15 1 1 CD cord-015369-72cjogxz 1780 16 ( ( -LRB- cord-015369-72cjogxz 1780 17 Faszienverschluss Faszienverschluss NNP cord-015369-72cjogxz 1780 18 ) ) -RRB- cord-015369-72cjogxz 1780 19 , , , cord-015369-72cjogxz 1780 20 1.2 1.2 CD cord-015369-72cjogxz 1780 21 ( ( -LRB- cord-015369-72cjogxz 1780 22 Lernkurve Lernkurve NNP cord-015369-72cjogxz 1780 23 ) ) -RRB- cord-015369-72cjogxz 1780 24 . . . cord-015369-72cjogxz 1781 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 1781 2 . . . cord-015369-72cjogxz 1782 1 Der Der NNP cord-015369-72cjogxz 1782 2 neue neue NNP cord-015369-72cjogxz 1782 3 TIC TIC NNP cord-015369-72cjogxz 1783 1 -Faszienverschlusstrokar -faszienverschlusstrokar UH cord-015369-72cjogxz 1783 2 ist ist DT cord-015369-72cjogxz 1783 3 als als NNP cord-015369-72cjogxz 1783 4 leicht leicht NNP cord-015369-72cjogxz 1783 5 erlernbares erlernbares NNPS cord-015369-72cjogxz 1783 6 , , , cord-015369-72cjogxz 1783 7 verlässlisches verlässlisches NNP cord-015369-72cjogxz 1783 8 System System NNP cord-015369-72cjogxz 1783 9 zum zum NNP cord-015369-72cjogxz 1783 10 Verschluss Verschluss NNP cord-015369-72cjogxz 1783 11 von von NNP cord-015369-72cjogxz 1783 12 Trokarinzisionen Trokarinzisionen NNP cord-015369-72cjogxz 1783 13 über über NNP cord-015369-72cjogxz 1784 1 10 10 CD cord-015369-72cjogxz 1784 2 mm mm NN cord-015369-72cjogxz 1784 3 geeignet geeignet NNS cord-015369-72cjogxz 1784 4 . . . cord-015369-72cjogxz 1785 1 Langzeiterfahrungen Langzeiterfahrungen NNP cord-015369-72cjogxz 1785 2 bleiben bleiben NNP cord-015369-72cjogxz 1785 3 abzuwarten abzuwarten NNP cord-015369-72cjogxz 1785 4 , , , cord-015369-72cjogxz 1785 5 jedoch jedoch NNP cord-015369-72cjogxz 1785 6 erscheint erscheint NNP cord-015369-72cjogxz 1785 7 insbesondere insbesondere NNP cord-015369-72cjogxz 1785 8 die die VBP cord-015369-72cjogxz 1785 9 Anwendung Anwendung NNP cord-015369-72cjogxz 1785 10 bei bei NNP cord-015369-72cjogxz 1785 11 adipösen adipösen NNP cord-015369-72cjogxz 1786 1 Patienten Patienten NNP cord-015369-72cjogxz 1787 1 und und NNP cord-015369-72cjogxz 1788 1 i -PRON- PRP cord-015369-72cjogxz 1788 2 m be VBP cord-015369-72cjogxz 1788 3 Rahmen Rahmen NNP cord-015369-72cjogxz 1788 4 von von NNP cord-015369-72cjogxz 1789 1 bariatrischen bariatrischen NNP cord-015369-72cjogxz 1790 1 Eingriffen Eingriffen NNP cord-015369-72cjogxz 1790 2 sinnvoll sinnvoll NNP cord-015369-72cjogxz 1790 3 . . . cord-015369-72cjogxz 1791 1 Biological biological JJ cord-015369-72cjogxz 1791 2 mesh mesh VBP cord-015369-72cjogxz 1791 3 in in IN cord-015369-72cjogxz 1791 4 complex complex JJ cord-015369-72cjogxz 1791 5 abdominal abdominal JJ cord-015369-72cjogxz 1791 6 wall wall NN cord-015369-72cjogxz 1791 7 repairlong repairlong NNP cord-015369-72cjogxz 1791 8 term term NN cord-015369-72cjogxz 1791 9 results result NNS cord-015369-72cjogxz 1791 10 of of IN cord-015369-72cjogxz 1791 11 use use NN cord-015369-72cjogxz 1791 12 of of IN cord-015369-72cjogxz 1791 13 Permacol Permacol NNP cord-015369-72cjogxz 1791 14 TM TM NNP cord-015369-72cjogxz 1791 15 ( ( -LRB- cord-015369-72cjogxz 1791 16 Porcine Porcine NNP cord-015369-72cjogxz 1791 17 Dermal Dermal NNP cord-015369-72cjogxz 1791 18 Collagen Collagen NNP cord-015369-72cjogxz 1791 19 ) ) -RRB- cord-015369-72cjogxz 1791 20 in in IN cord-015369-72cjogxz 1791 21 a a DT cord-015369-72cjogxz 1791 22 single single JJ cord-015369-72cjogxz 1791 23 institution institution NN cord-015369-72cjogxz 1791 24 Torbay Torbay NNP cord-015369-72cjogxz 1791 25 Hospital Hospital NNP cord-015369-72cjogxz 1791 26 , , , cord-015369-72cjogxz 1791 27 Torquay Torquay NNP cord-015369-72cjogxz 1791 28 , , , cord-015369-72cjogxz 1791 29 UK UK NNP cord-015369-72cjogxz 1791 30 Background Background NNP cord-015369-72cjogxz 1791 31 . . . cord-015369-72cjogxz 1792 1 Abdominal abdominal JJ cord-015369-72cjogxz 1792 2 wall wall NN cord-015369-72cjogxz 1792 3 repair repair NN cord-015369-72cjogxz 1792 4 ( ( -LRB- cord-015369-72cjogxz 1792 5 AWR AWR NNP cord-015369-72cjogxz 1792 6 ) ) -RRB- cord-015369-72cjogxz 1793 1 if if IN cord-015369-72cjogxz 1793 2 poor poor JJ cord-015369-72cjogxz 1793 3 tissues tissue NNS cord-015369-72cjogxz 1793 4 , , , cord-015369-72cjogxz 1793 5 contamination contamination NN cord-015369-72cjogxz 1793 6 , , , cord-015369-72cjogxz 1793 7 intestinal intestinal JJ cord-015369-72cjogxz 1793 8 fistula fistula NN cord-015369-72cjogxz 1793 9 , , , cord-015369-72cjogxz 1793 10 anastomosis anastomosis NN cord-015369-72cjogxz 1793 11 , , , cord-015369-72cjogxz 1793 12 stoma stoma NN cord-015369-72cjogxz 1793 13 and and CC cord-015369-72cjogxz 1793 14 mesh mesh NN cord-015369-72cjogxz 1793 15 impingement impingement NN cord-015369-72cjogxz 1793 16 on on IN cord-015369-72cjogxz 1793 17 bowel bowel NN cord-015369-72cjogxz 1793 18 represent represent VBP cord-015369-72cjogxz 1793 19 formidable formidable JJ cord-015369-72cjogxz 1793 20 surgical surgical JJ cord-015369-72cjogxz 1793 21 challenges challenge NNS cord-015369-72cjogxz 1793 22 . . . cord-015369-72cjogxz 1794 1 Synthetic synthetic JJ cord-015369-72cjogxz 1794 2 mesh mesh NN cord-015369-72cjogxz 1794 3 or or CC cord-015369-72cjogxz 1794 4 suture suture NN cord-015369-72cjogxz 1794 5 repair repair NN cord-015369-72cjogxz 1794 6 is be VBZ cord-015369-72cjogxz 1794 7 inappropriate inappropriate JJ cord-015369-72cjogxz 1794 8 . . . cord-015369-72cjogxz 1795 1 Biological biological JJ cord-015369-72cjogxz 1795 2 meshes mesh NNS cord-015369-72cjogxz 1795 3 are be VBP cord-015369-72cjogxz 1795 4 biocompatible biocompatible JJ cord-015369-72cjogxz 1795 5 , , , cord-015369-72cjogxz 1795 6 offer offer VBP cord-015369-72cjogxz 1795 7 resistance resistance NN cord-015369-72cjogxz 1795 8 to to IN cord-015369-72cjogxz 1795 9 contamination contamination NN cord-015369-72cjogxz 1795 10 , , , cord-015369-72cjogxz 1795 11 minimal minimal JJ cord-015369-72cjogxz 1795 12 adhesion adhesion NN cord-015369-72cjogxz 1795 13 or or CC cord-015369-72cjogxz 1795 14 fistula fistula NN cord-015369-72cjogxz 1795 15 formation formation NN cord-015369-72cjogxz 1795 16 but but CC cord-015369-72cjogxz 1795 17 retain retain VB cord-015369-72cjogxz 1795 18 strength strength NN cord-015369-72cjogxz 1795 19 . . . cord-015369-72cjogxz 1796 1 We -PRON- PRP cord-015369-72cjogxz 1796 2 use use VBP cord-015369-72cjogxz 1796 3 Permacol Permacol NNP cord-015369-72cjogxz 1796 4 TM TM NNP cord-015369-72cjogxz 1796 5 -crosslinked -crosslinked CD cord-015369-72cjogxz 1796 6 porcine porcine JJ cord-015369-72cjogxz 1796 7 dermal dermal JJ cord-015369-72cjogxz 1796 8 collagen collagen NN cord-015369-72cjogxz 1796 9 -in -in : cord-015369-72cjogxz 1796 10 these these DT cord-015369-72cjogxz 1796 11 cases case NNS cord-015369-72cjogxz 1796 12 and and CC cord-015369-72cjogxz 1796 13 present present JJ cord-015369-72cjogxz 1796 14 data datum NNS cord-015369-72cjogxz 1796 15 with with IN cord-015369-72cjogxz 1796 16 long long JJ cord-015369-72cjogxz 1796 17 follow follow VB cord-015369-72cjogxz 1796 18 up up RP cord-015369-72cjogxz 1796 19 . . . cord-015369-72cjogxz 1797 1 Methods method NNS cord-015369-72cjogxz 1797 2 . . . cord-015369-72cjogxz 1798 1 Retrospective retrospective JJ cord-015369-72cjogxz 1798 2 review review NN cord-015369-72cjogxz 1798 3 of of IN cord-015369-72cjogxz 1798 4 patients patient NNS cord-015369-72cjogxz 1798 5 treated treat VBN cord-015369-72cjogxz 1798 6 with with IN cord-015369-72cjogxz 1798 7 Permacol Permacol NNP cord-015369-72cjogxz 1798 8 TM TM NNP cord-015369-72cjogxz 1798 9 for for IN cord-015369-72cjogxz 1798 10 : : : cord-015369-72cjogxz 1798 11 1 1 CD cord-015369-72cjogxz 1798 12 . . . cord-015369-72cjogxz 1799 1 recurrent recurrent JJ cord-015369-72cjogxz 1799 2 incisional incisional JJ cord-015369-72cjogxz 1799 3 hernia hernia NN cord-015369-72cjogxz 1799 4 AE AE NNP cord-015369-72cjogxz 1799 5 mesh mesh NN cord-015369-72cjogxz 1799 6 ; ; : cord-015369-72cjogxz 1799 7 2 2 LS cord-015369-72cjogxz 1799 8 . . . cord-015369-72cjogxz 1799 9 post post NNP cord-015369-72cjogxz 1799 10 laparostomy laparostomy NNP cord-015369-72cjogxz 1799 11 ; ; . cord-015369-72cjogxz 1800 1 3 3 LS cord-015369-72cjogxz 1800 2 . . . cord-015369-72cjogxz 1801 1 enterocutaneous enterocutaneous JJ cord-015369-72cjogxz 1801 2 fistula fistula NN cord-015369-72cjogxz 1801 3 ; ; : cord-015369-72cjogxz 1801 4 4 4 CD cord-015369-72cjogxz 1801 5 . . . cord-015369-72cjogxz 1802 1 contamination contamination NN cord-015369-72cjogxz 1802 2 by by IN cord-015369-72cjogxz 1802 3 anastomosis anastomosis NN cord-015369-72cjogxz 1802 4 ; ; : cord-015369-72cjogxz 1802 5 5 5 CD cord-015369-72cjogxz 1802 6 . . . cord-015369-72cjogxz 1803 1 parastomal parastomal NNP cord-015369-72cjogxz 1803 2 hernia hernia NNP cord-015369-72cjogxz 1803 3 . . . cord-015369-72cjogxz 1804 1 Results result NNS cord-015369-72cjogxz 1804 2 . . . cord-015369-72cjogxz 1805 1 Twenty twenty CD cord-015369-72cjogxz 1805 2 - - HYPH cord-015369-72cjogxz 1805 3 nine nine CD cord-015369-72cjogxz 1805 4 patients patient NNS cord-015369-72cjogxz 1805 5 were be VBD cord-015369-72cjogxz 1805 6 identified identify VBN cord-015369-72cjogxz 1805 7 . . . cord-015369-72cjogxz 1806 1 19 19 CD cord-015369-72cjogxz 1806 2 with with IN cord-015369-72cjogxz 1806 3 acute acute JJ cord-015369-72cjogxz 1806 4 or or CC cord-015369-72cjogxz 1806 5 chronic chronic JJ cord-015369-72cjogxz 1806 6 abdominal abdominal JJ cord-015369-72cjogxz 1806 7 defects defect NNS cord-015369-72cjogxz 1806 8 ; ; : cord-015369-72cjogxz 1806 9 10 10 CD cord-015369-72cjogxz 1806 10 with with IN cord-015369-72cjogxz 1806 11 parastomal parastomal NNP cord-015369-72cjogxz 1806 12 hernia hernia NN cord-015369-72cjogxz 1806 13 . . . cord-015369-72cjogxz 1807 1 Defects defect NNS cord-015369-72cjogxz 1807 2 sizes size NNS cord-015369-72cjogxz 1807 3 from from IN cord-015369-72cjogxz 1807 4 80 80 CD cord-015369-72cjogxz 1807 5 to to TO cord-015369-72cjogxz 1807 6 200 200 CD cord-015369-72cjogxz 1807 7 cm cm NNS cord-015369-72cjogxz 1807 8 2 2 CD cord-015369-72cjogxz 1807 9 . . . cord-015369-72cjogxz 1808 1 Median median JJ cord-015369-72cjogxz 1808 2 age age NN cord-015369-72cjogxz 1808 3 56 56 CD cord-015369-72cjogxz 1809 1 ( ( -LRB- cord-015369-72cjogxz 1809 2 range range NNP cord-015369-72cjogxz 1809 3 28 28 CD cord-015369-72cjogxz 1809 4 - - SYM cord-015369-72cjogxz 1809 5 84 84 CD cord-015369-72cjogxz 1809 6 ) ) -RRB- cord-015369-72cjogxz 1809 7 years year NNS cord-015369-72cjogxz 1809 8 and and CC cord-015369-72cjogxz 1809 9 follow follow VB cord-015369-72cjogxz 1809 10 up up RP cord-015369-72cjogxz 1809 11 51 51 CD cord-015369-72cjogxz 1809 12 ( ( -LRB- cord-015369-72cjogxz 1809 13 36 36 CD cord-015369-72cjogxz 1809 14 - - SYM cord-015369-72cjogxz 1809 15 67 67 CD cord-015369-72cjogxz 1809 16 ) ) -RRB- cord-015369-72cjogxz 1809 17 months month NNS cord-015369-72cjogxz 1809 18 . . . cord-015369-72cjogxz 1810 1 Eleven eleven CD cord-015369-72cjogxz 1810 2 cases case NNS cord-015369-72cjogxz 1810 3 AWR AWR NNP cord-015369-72cjogxz 1810 4 -4 -4 ADD cord-015369-72cjogxz 1811 1 with with IN cord-015369-72cjogxz 1811 2 anastomosis anastomosis NN cord-015369-72cjogxz 1811 3 , , , cord-015369-72cjogxz 1811 4 1 1 CD cord-015369-72cjogxz 1811 5 paracolostomy paracolostomy NN cord-015369-72cjogxz 1811 6 hernia hernia NN cord-015369-72cjogxz 1811 7 . . . cord-015369-72cjogxz 1812 1 Eight eight CD cord-015369-72cjogxz 1812 2 enterocutaneous enterocutaneous JJ cord-015369-72cjogxz 1812 3 fistula fistula NN cord-015369-72cjogxz 1812 4 with with IN cord-015369-72cjogxz 1812 5 deficient deficient JJ cord-015369-72cjogxz 1812 6 abdominal abdominal JJ cord-015369-72cjogxz 1812 7 wall wall NN cord-015369-72cjogxz 1812 8 ; ; : cord-015369-72cjogxz 1812 9 3 3 CD cord-015369-72cjogxz 1812 10 with with IN cord-015369-72cjogxz 1812 11 fistula fistula NN cord-015369-72cjogxz 1812 12 associated associate VBN cord-015369-72cjogxz 1812 13 with with IN cord-015369-72cjogxz 1812 14 mesh mesh NN cord-015369-72cjogxz 1812 15 , , , cord-015369-72cjogxz 1812 16 all all RB cord-015369-72cjogxz 1812 17 with with IN cord-015369-72cjogxz 1812 18 anastomosis anastomosis NN cord-015369-72cjogxz 1812 19 . . . cord-015369-72cjogxz 1813 1 4 4 LS cord-015369-72cjogxz 1813 2 recurrent recurrent NN cord-015369-72cjogxz 1813 3 of of IN cord-015369-72cjogxz 1813 4 10 10 CD cord-015369-72cjogxz 1813 5 parastomal parastomal NN cord-015369-72cjogxz 1813 6 hernias hernia NNS cord-015369-72cjogxz 1813 7 . . . cord-015369-72cjogxz 1814 1 Repairs repair NNS cord-015369-72cjogxz 1814 2 by by IN cord-015369-72cjogxz 1814 3 onlay onlay NN cord-015369-72cjogxz 1814 4 , , , cord-015369-72cjogxz 1814 5 inlay inlay NN cord-015369-72cjogxz 1814 6 and and CC cord-015369-72cjogxz 1814 7 sublay sublay NN cord-015369-72cjogxz 1814 8 . . . cord-015369-72cjogxz 1815 1 Sixteen sixteen CD cord-015369-72cjogxz 1815 2 cases case NNS cord-015369-72cjogxz 1815 3 had have VBD cord-015369-72cjogxz 1815 4 no no DT cord-015369-72cjogxz 1815 5 complications complication NNS cord-015369-72cjogxz 1815 6 . . . cord-015369-72cjogxz 1816 1 Major major JJ cord-015369-72cjogxz 1816 2 complications complication NNS cord-015369-72cjogxz 1816 3 in in IN cord-015369-72cjogxz 1816 4 6 6 CD cord-015369-72cjogxz 1816 5 patients patient NNS cord-015369-72cjogxz 1816 6 -2 -2 JJR cord-015369-72cjogxz 1816 7 early early JJ cord-015369-72cjogxz 1816 8 deaths death NNS cord-015369-72cjogxz 1816 9 ( ( -LRB- cord-015369-72cjogxz 1816 10 myocardial myocardial NNP cord-015369-72cjogxz 1816 11 infarct infarct NN cord-015369-72cjogxz 1816 12 and and CC cord-015369-72cjogxz 1816 13 multiorgan multiorgan NNP cord-015369-72cjogxz 1816 14 failure failure NN cord-015369-72cjogxz 1816 15 ) ) -RRB- cord-015369-72cjogxz 1816 16 ; ; : cord-015369-72cjogxz 1816 17 2 2 CD cord-015369-72cjogxz 1816 18 recurrent recurrent JJ cord-015369-72cjogxz 1816 19 hernia hernia NN cord-015369-72cjogxz 1816 20 , , , cord-015369-72cjogxz 1816 21 1 1 CD cord-015369-72cjogxz 1816 22 colonic colonic JJ cord-015369-72cjogxz 1816 23 ischaemia ischaemia NN cord-015369-72cjogxz 1816 24 requiring require VBG cord-015369-72cjogxz 1816 25 relaparotomy relaparotomy NN cord-015369-72cjogxz 1816 26 and and CC cord-015369-72cjogxz 1816 27 1 1 CD cord-015369-72cjogxz 1816 28 intra intra JJ cord-015369-72cjogxz 1816 29 abdominal abdominal JJ cord-015369-72cjogxz 1816 30 abscess abscess NN cord-015369-72cjogxz 1816 31 requiring require VBG cord-015369-72cjogxz 1816 32 percutaneous percutaneous JJ cord-015369-72cjogxz 1816 33 drainage drainage NN cord-015369-72cjogxz 1816 34 . . . cord-015369-72cjogxz 1817 1 7 7 CD cord-015369-72cjogxz 1817 2 minor minor JJ cord-015369-72cjogxz 1817 3 complications complication NNS cord-015369-72cjogxz 1817 4 comprised comprise VBN cord-015369-72cjogxz 1817 5 4 4 CD cord-015369-72cjogxz 1817 6 wound wound NN cord-015369-72cjogxz 1817 7 infections infection NNS cord-015369-72cjogxz 1817 8 , , , cord-015369-72cjogxz 1817 9 1 1 CD cord-015369-72cjogxz 1817 10 sinus sinus NN cord-015369-72cjogxz 1817 11 and and CC cord-015369-72cjogxz 1817 12 2 2 CD cord-015369-72cjogxz 1817 13 seroma seroma NNS cord-015369-72cjogxz 1817 14 . . . cord-015369-72cjogxz 1818 1 There there EX cord-015369-72cjogxz 1818 2 were be VBD cord-015369-72cjogxz 1818 3 no no DT cord-015369-72cjogxz 1818 4 mesh mesh NN cord-015369-72cjogxz 1818 5 rejections rejection NNS cord-015369-72cjogxz 1818 6 and and CC cord-015369-72cjogxz 1818 7 no no DT cord-015369-72cjogxz 1818 8 further further JJ cord-015369-72cjogxz 1818 9 complications complication NNS cord-015369-72cjogxz 1818 10 . . . cord-015369-72cjogxz 1819 1 Conclusions conclusion NNS cord-015369-72cjogxz 1819 2 . . . cord-015369-72cjogxz 1820 1 In in IN cord-015369-72cjogxz 1820 2 difficult difficult JJ cord-015369-72cjogxz 1820 3 anterior anterior JJ cord-015369-72cjogxz 1820 4 abdominal abdominal JJ cord-015369-72cjogxz 1820 5 wall wall NN cord-015369-72cjogxz 1820 6 repair repair NN cord-015369-72cjogxz 1820 7 Permacol Permacol NNP cord-015369-72cjogxz 1820 8 TM TM NNP cord-015369-72cjogxz 1820 9 is be VBZ cord-015369-72cjogxz 1820 10 effective effective JJ cord-015369-72cjogxz 1820 11 , , , cord-015369-72cjogxz 1820 12 biocompatible biocompatible JJ cord-015369-72cjogxz 1820 13 , , , cord-015369-72cjogxz 1820 14 resistant resistant JJ cord-015369-72cjogxz 1820 15 to to IN cord-015369-72cjogxz 1820 16 infection infection NN cord-015369-72cjogxz 1820 17 , , , cord-015369-72cjogxz 1820 18 contamination contamination NN cord-015369-72cjogxz 1820 19 and and CC cord-015369-72cjogxz 1820 20 can can MD cord-015369-72cjogxz 1820 21 sit sit VB cord-015369-72cjogxz 1820 22 in in IN cord-015369-72cjogxz 1820 23 contact contact NN cord-015369-72cjogxz 1820 24 with with IN cord-015369-72cjogxz 1820 25 bowel bowel NN cord-015369-72cjogxz 1820 26 . . . cord-015369-72cjogxz 1821 1 The the DT cord-015369-72cjogxz 1821 2 new new JJ cord-015369-72cjogxz 1821 3 flexible flexible JJ cord-015369-72cjogxz 1821 4 conductive conductive JJ cord-015369-72cjogxz 1821 5 bipolar bipolar JJ cord-015369-72cjogxz 1821 6 loop loop NN cord-015369-72cjogxz 1821 7 - - HYPH cord-015369-72cjogxz 1821 8 electrode electrode NN cord-015369-72cjogxz 1821 9 for for IN cord-015369-72cjogxz 1821 10 continuous continuous JJ cord-015369-72cjogxz 1821 11 neuromonitoring neuromonitoring NN cord-015369-72cjogxz 1821 12 of of IN cord-015369-72cjogxz 1821 13 the the DT cord-015369-72cjogxz 1821 14 recurrent recurrent JJ cord-015369-72cjogxz 1821 15 laryngeal laryngeal NN cord-015369-72cjogxz 1821 16 nerve nerve NN cord-015369-72cjogxz 1821 17 by by IN cord-015369-72cjogxz 1821 18 vagus vagus JJ cord-015369-72cjogxz 1821 19 nerve nerve NN cord-015369-72cjogxz 1821 20 stimulation stimulation NN cord-015369-72cjogxz 1822 1 -first -first WDT cord-015369-72cjogxz 1822 2 experience experience NN cord-015369-72cjogxz 1822 3 with with IN cord-015369-72cjogxz 1822 4 the the DT cord-015369-72cjogxz 1822 5 3rd 3rd JJ cord-015369-72cjogxz 1822 6 and and CC cord-015369-72cjogxz 1822 7 4th 4th JJ cord-015369-72cjogxz 1822 8 generation generation NN cord-015369-72cjogxz 1822 9 Background Background NNP cord-015369-72cjogxz 1822 10 . . . cord-015369-72cjogxz 1823 1 Ascites ascite NNS cord-015369-72cjogxz 1823 2 leaks leak VBZ cord-015369-72cjogxz 1823 3 ( ( -LRB- cord-015369-72cjogxz 1823 4 AL AL NNP cord-015369-72cjogxz 1823 5 ) ) -RRB- cord-015369-72cjogxz 1823 6 in in IN cord-015369-72cjogxz 1823 7 patients patient NNS cord-015369-72cjogxz 1823 8 with with IN cord-015369-72cjogxz 1823 9 end end NN cord-015369-72cjogxz 1823 10 stage stage NN cord-015369-72cjogxz 1823 11 liver liver NN cord-015369-72cjogxz 1823 12 disease disease NN cord-015369-72cjogxz 1823 13 ( ( -LRB- cord-015369-72cjogxz 1823 14 ESLD ESLD NNP cord-015369-72cjogxz 1823 15 ) ) -RRB- cord-015369-72cjogxz 1823 16 are be VBP cord-015369-72cjogxz 1823 17 commonly commonly RB cord-015369-72cjogxz 1823 18 associated associate VBN cord-015369-72cjogxz 1823 19 with with IN cord-015369-72cjogxz 1823 20 recent recent JJ cord-015369-72cjogxz 1823 21 interventions intervention NNS cord-015369-72cjogxz 1823 22 or or CC cord-015369-72cjogxz 1823 23 ruptured rupture VBN cord-015369-72cjogxz 1823 24 hernias hernia NNS cord-015369-72cjogxz 1823 25 and and CC cord-015369-72cjogxz 1823 26 are be VBP cord-015369-72cjogxz 1823 27 associated associate VBN cord-015369-72cjogxz 1823 28 with with IN cord-015369-72cjogxz 1823 29 significant significant JJ cord-015369-72cjogxz 1823 30 morbidity morbidity NN cord-015369-72cjogxz 1823 31 and and CC cord-015369-72cjogxz 1823 32 mortality mortality NN cord-015369-72cjogxz 1823 33 regardless regardless RB cord-015369-72cjogxz 1823 34 if if IN cord-015369-72cjogxz 1823 35 they -PRON- PRP cord-015369-72cjogxz 1823 36 are be VBP cord-015369-72cjogxz 1823 37 medically medically RB cord-015369-72cjogxz 1823 38 or or CC cord-015369-72cjogxz 1823 39 surgically surgically RB cord-015369-72cjogxz 1823 40 managed manage VBN cord-015369-72cjogxz 1823 41 . . . cord-015369-72cjogxz 1824 1 Methods method NNS cord-015369-72cjogxz 1824 2 . . . cord-015369-72cjogxz 1825 1 In in IN cord-015369-72cjogxz 1825 2 a a DT cord-015369-72cjogxz 1825 3 pilot pilot NN cord-015369-72cjogxz 1825 4 study study NN cord-015369-72cjogxz 1825 5 , , , cord-015369-72cjogxz 1825 6 14 14 CD cord-015369-72cjogxz 1825 7 ESLD ESLD NNP cord-015369-72cjogxz 1825 8 patients patient NNS cord-015369-72cjogxz 1825 9 with with IN cord-015369-72cjogxz 1825 10 a a DT cord-015369-72cjogxz 1825 11 median median JJ cord-015369-72cjogxz 1825 12 MELD meld VB cord-015369-72cjogxz 1825 13 score score NN cord-015369-72cjogxz 1825 14 of of IN cord-015369-72cjogxz 1825 15 23 23 CD cord-015369-72cjogxz 1825 16 ( ( -LRB- cord-015369-72cjogxz 1825 17 range range NNP cord-015369-72cjogxz 1825 18 8 8 CD cord-015369-72cjogxz 1825 19 - - SYM cord-015369-72cjogxz 1825 20 33 33 CD cord-015369-72cjogxz 1825 21 ) ) -RRB- cord-015369-72cjogxz 1825 22 underwent undergo VBD cord-015369-72cjogxz 1825 23 treatment treatment NN cord-015369-72cjogxz 1825 24 of of IN cord-015369-72cjogxz 1825 25 ALs ALs NNP cord-015369-72cjogxz 1825 26 with with IN cord-015369-72cjogxz 1825 27 topic topic NN cord-015369-72cjogxz 1825 28 fibrin fibrin NN cord-015369-72cjogxz 1825 29 glue glue NN cord-015369-72cjogxz 1825 30 injection injection NN cord-015369-72cjogxz 1825 31 around around IN cord-015369-72cjogxz 1825 32 the the DT cord-015369-72cjogxz 1825 33 leak leak NN cord-015369-72cjogxz 1825 34 after after IN cord-015369-72cjogxz 1825 35 failing fail VBG cord-015369-72cjogxz 1825 36 conservative conservative JJ cord-015369-72cjogxz 1825 37 therapy therapy NN cord-015369-72cjogxz 1825 38 . . . cord-015369-72cjogxz 1826 1 Results result NNS cord-015369-72cjogxz 1826 2 . . . cord-015369-72cjogxz 1827 1 Mean mean JJ cord-015369-72cjogxz 1827 2 age age NN cord-015369-72cjogxz 1827 3 of of IN cord-015369-72cjogxz 1827 4 the the DT cord-015369-72cjogxz 1827 5 ten ten CD cord-015369-72cjogxz 1827 6 men man NNS cord-015369-72cjogxz 1827 7 and and CC cord-015369-72cjogxz 1827 8 four four CD cord-015369-72cjogxz 1827 9 women woman NNS cord-015369-72cjogxz 1827 10 was be VBD cord-015369-72cjogxz 1827 11 50 50 CD cord-015369-72cjogxz 1828 1 ( ( -LRB- cord-015369-72cjogxz 1828 2 range range NNP cord-015369-72cjogxz 1828 3 26 26 CD cord-015369-72cjogxz 1828 4 - - SYM cord-015369-72cjogxz 1828 5 67 67 CD cord-015369-72cjogxz 1828 6 ) ) -RRB- cord-015369-72cjogxz 1828 7 years year NNS cord-015369-72cjogxz 1828 8 . . . cord-015369-72cjogxz 1829 1 Underlying underlie VBG cord-015369-72cjogxz 1829 2 ESLDs esld NNS cord-015369-72cjogxz 1829 3 were be VBD cord-015369-72cjogxz 1829 4 chronic chronic JJ cord-015369-72cjogxz 1829 5 hepatitis hepatitis NN cord-015369-72cjogxz 1829 6 C C NNP cord-015369-72cjogxz 1829 7 ( ( -LRB- cord-015369-72cjogxz 1829 8 n n NN cord-015369-72cjogxz 1829 9 ¼ ¼ NNP cord-015369-72cjogxz 1829 10 5 5 CD cord-015369-72cjogxz 1829 11 ) ) -RRB- cord-015369-72cjogxz 1829 12 , , , cord-015369-72cjogxz 1829 13 alcoholic alcoholic JJ cord-015369-72cjogxz 1829 14 LD LD NNP cord-015369-72cjogxz 1829 15 ( ( -LRB- cord-015369-72cjogxz 1829 16 n n NN cord-015369-72cjogxz 1829 17 ¼ ¼ NNP cord-015369-72cjogxz 1829 18 2 2 CD cord-015369-72cjogxz 1829 19 ) ) -RRB- cord-015369-72cjogxz 1830 1 , , , cord-015369-72cjogxz 1830 2 cryptogenic cryptogenic NNP cord-015369-72cjogxz 1830 3 cirrhosis cirrhosis NNP cord-015369-72cjogxz 1830 4 ( ( -LRB- cord-015369-72cjogxz 1830 5 n n NNP cord-015369-72cjogxz 1830 6 ¼ ¼ NNP cord-015369-72cjogxz 1830 7 2 2 CD cord-015369-72cjogxz 1830 8 ) ) -RRB- cord-015369-72cjogxz 1830 9 miscellaneous miscellaneous JJ cord-015369-72cjogxz 1830 10 ( ( -LRB- cord-015369-72cjogxz 1830 11 n n NN cord-015369-72cjogxz 1830 12 ¼ ¼ NNP cord-015369-72cjogxz 1830 13 5 5 CD cord-015369-72cjogxz 1830 14 ) ) -RRB- cord-015369-72cjogxz 1830 15 . . . cord-015369-72cjogxz 1831 1 There there EX cord-015369-72cjogxz 1831 2 were be VBD cord-015369-72cjogxz 1831 3 six six CD cord-015369-72cjogxz 1831 4 leaking leaking NN cord-015369-72cjogxz 1831 5 incisions incision NNS cord-015369-72cjogxz 1831 6 post post VBP cord-015369-72cjogxz 1831 7 emergent emergent JJ cord-015369-72cjogxz 1831 8 hernia hernia NN cord-015369-72cjogxz 1831 9 repair repair NN cord-015369-72cjogxz 1831 10 ( ( -LRB- cord-015369-72cjogxz 1831 11 one one CD cord-015369-72cjogxz 1831 12 inguinal inguinal JJ cord-015369-72cjogxz 1831 13 , , , cord-015369-72cjogxz 1831 14 two two CD cord-015369-72cjogxz 1831 15 umbilical umbilical JJ cord-015369-72cjogxz 1831 16 , , , cord-015369-72cjogxz 1831 17 one one CD cord-015369-72cjogxz 1831 18 ventral ventral NN cord-015369-72cjogxz 1831 19 ) ) -RRB- cord-015369-72cjogxz 1831 20 , , , cord-015369-72cjogxz 1831 21 two two CD cord-015369-72cjogxz 1831 22 leaking leak VBG cord-015369-72cjogxz 1831 23 / / SYM cord-015369-72cjogxz 1831 24 ruptured ruptured JJ cord-015369-72cjogxz 1831 25 umbilical umbilical JJ cord-015369-72cjogxz 1831 26 hernias hernia NNS cord-015369-72cjogxz 1831 27 , , , cord-015369-72cjogxz 1831 28 four four CD cord-015369-72cjogxz 1831 29 leaking leak VBG cord-015369-72cjogxz 1831 30 paracentesis paracentesis NN cord-015369-72cjogxz 1831 31 sites site NNS cord-015369-72cjogxz 1831 32 , , , cord-015369-72cjogxz 1831 33 one one CD cord-015369-72cjogxz 1831 34 leaking leak VBG cord-015369-72cjogxz 1831 35 JP JP NNP cord-015369-72cjogxz 1831 36 drain drain NN cord-015369-72cjogxz 1831 37 canal canal NN cord-015369-72cjogxz 1831 38 and and CC cord-015369-72cjogxz 1831 39 one one CD cord-015369-72cjogxz 1831 40 leaking leak VBG cord-015369-72cjogxz 1831 41 laparoscopy laparoscopy RB cord-015369-72cjogxz 1831 42 trocar trocar NN cord-015369-72cjogxz 1831 43 site site NN cord-015369-72cjogxz 1831 44 . . . cord-015369-72cjogxz 1832 1 Average average JJ cord-015369-72cjogxz 1832 2 ascites ascites NN cord-015369-72cjogxz 1832 3 leak leak NN cord-015369-72cjogxz 1832 4 volume volume NN cord-015369-72cjogxz 1832 5 per per IN cord-015369-72cjogxz 1832 6 day day NN cord-015369-72cjogxz 1832 7 was be VBD cord-015369-72cjogxz 1832 8 1000 1000 CD cord-015369-72cjogxz 1832 9 mL ml NN cord-015369-72cjogxz 1832 10 ( ( -LRB- cord-015369-72cjogxz 1832 11 range range NN cord-015369-72cjogxz 1832 12 400 400 CD cord-015369-72cjogxz 1832 13 mL-2000 mL-2000 NNS cord-015369-72cjogxz 1832 14 mL ml NN cord-015369-72cjogxz 1832 15 ) ) -RRB- cord-015369-72cjogxz 1832 16 . . . cord-015369-72cjogxz 1833 1 All all DT cord-015369-72cjogxz 1833 2 leaks leak NNS cord-015369-72cjogxz 1833 3 were be VBD cord-015369-72cjogxz 1833 4 immediately immediately RB cord-015369-72cjogxz 1833 5 resolved resolve VBN cord-015369-72cjogxz 1833 6 with with IN cord-015369-72cjogxz 1833 7 a a DT cord-015369-72cjogxz 1833 8 3 3 CD cord-015369-72cjogxz 1833 9 - - HYPH cord-015369-72cjogxz 1833 10 5cc 5cc NN cord-015369-72cjogxz 1833 11 fibrin fibrin NN cord-015369-72cjogxz 1833 12 glue glue NN cord-015369-72cjogxz 1833 13 injection injection NN cord-015369-72cjogxz 1833 14 . . . cord-015369-72cjogxz 1834 1 Five five CD cord-015369-72cjogxz 1834 2 recurred recur VBD cord-015369-72cjogxz 1834 3 requireding requirede VBG cord-015369-72cjogxz 1834 4 re re NN cord-015369-72cjogxz 1834 5 - - NN cord-015369-72cjogxz 1834 6 injection injection NN cord-015369-72cjogxz 1834 7 ( ( -LRB- cord-015369-72cjogxz 1834 8 4 4 CD cord-015369-72cjogxz 1834 9 within within IN cord-015369-72cjogxz 1834 10 24 24 CD cord-015369-72cjogxz 1834 11 h h NN cord-015369-72cjogxz 1834 12 ) ) -RRB- cord-015369-72cjogxz 1834 13 . . . cord-015369-72cjogxz 1835 1 Following follow VBG cord-015369-72cjogxz 1835 2 injection injection NN cord-015369-72cjogxz 1835 3 , , , cord-015369-72cjogxz 1835 4 albumin albumin NN cord-015369-72cjogxz 1835 5 levels level NNS cord-015369-72cjogxz 1835 6 , , , cord-015369-72cjogxz 1835 7 mental mental JJ cord-015369-72cjogxz 1835 8 status status NN cord-015369-72cjogxz 1835 9 and and CC cord-015369-72cjogxz 1835 10 MELD meld NN cord-015369-72cjogxz 1835 11 - - HYPH cord-015369-72cjogxz 1835 12 scores score NNS cord-015369-72cjogxz 1835 13 improved improve VBD cord-015369-72cjogxz 1835 14 in in IN cord-015369-72cjogxz 1835 15 the the DT cord-015369-72cjogxz 1835 16 majority majority NN cord-015369-72cjogxz 1835 17 of of IN cord-015369-72cjogxz 1835 18 patients patient NNS cord-015369-72cjogxz 1835 19 within within IN cord-015369-72cjogxz 1835 20 one one CD cord-015369-72cjogxz 1835 21 week week NN cord-015369-72cjogxz 1835 22 . . . cord-015369-72cjogxz 1836 1 Five five CD cord-015369-72cjogxz 1836 2 patients patient NNS cord-015369-72cjogxz 1836 3 underwent undergo VBD cord-015369-72cjogxz 1836 4 ( ( -LRB- cord-015369-72cjogxz 1836 5 liver liver NN cord-015369-72cjogxz 1836 6 transplantation transplantation NN cord-015369-72cjogxz 1836 7 ) ) -RRB- cord-015369-72cjogxz 1837 1 LT LT NNP cord-015369-72cjogxz 1837 2 median median NN cord-015369-72cjogxz 1837 3 15 15 CD cord-015369-72cjogxz 1838 1 ( ( -LRB- cord-015369-72cjogxz 1838 2 range range NNP cord-015369-72cjogxz 1838 3 4 4 CD cord-015369-72cjogxz 1838 4 - - SYM cord-015369-72cjogxz 1838 5 270 270 CD cord-015369-72cjogxz 1838 6 ) ) -RRB- cord-015369-72cjogxz 1838 7 days day NNS cord-015369-72cjogxz 1838 8 post post NN cord-015369-72cjogxz 1838 9 - - NN cord-015369-72cjogxz 1838 10 injection injection NN cord-015369-72cjogxz 1838 11 . . . cord-015369-72cjogxz 1839 1 Three three CD cord-015369-72cjogxz 1839 2 patients patient NNS cord-015369-72cjogxz 1839 3 died die VBD cord-015369-72cjogxz 1839 4 ( ( -LRB- cord-015369-72cjogxz 1839 5 two two CD cord-015369-72cjogxz 1839 6 from from IN cord-015369-72cjogxz 1839 7 sepsis sepsis NN cord-015369-72cjogxz 1839 8 one one CD cord-015369-72cjogxz 1839 9 from from IN cord-015369-72cjogxz 1839 10 metastatic metastatic JJ cord-015369-72cjogxz 1839 11 cancer cancer NN cord-015369-72cjogxz 1839 12 ) ) -RRB- cord-015369-72cjogxz 1839 13 , , , cord-015369-72cjogxz 1839 14 the the DT cord-015369-72cjogxz 1839 15 remaining remain VBG cord-015369-72cjogxz 1839 16 patients patient NNS cord-015369-72cjogxz 1839 17 were be VBD cord-015369-72cjogxz 1839 18 not not RB cord-015369-72cjogxz 1839 19 accepted accept VBN cord-015369-72cjogxz 1839 20 as as IN cord-015369-72cjogxz 1839 21 LT LT NNP cord-015369-72cjogxz 1839 22 candidates candidate NNS cord-015369-72cjogxz 1839 23 . . . cord-015369-72cjogxz 1840 1 Conclusions conclusion NNS cord-015369-72cjogxz 1840 2 . . . cord-015369-72cjogxz 1841 1 Fibrin fibrin NN cord-015369-72cjogxz 1841 2 glue glue NN cord-015369-72cjogxz 1841 3 injection injection NN cord-015369-72cjogxz 1841 4 is be VBZ cord-015369-72cjogxz 1841 5 a a DT cord-015369-72cjogxz 1841 6 cost cost NN cord-015369-72cjogxz 1841 7 effective effective JJ cord-015369-72cjogxz 1841 8 , , , cord-015369-72cjogxz 1841 9 simple simple JJ cord-015369-72cjogxz 1841 10 and and CC cord-015369-72cjogxz 1841 11 safe safe JJ cord-015369-72cjogxz 1841 12 bedside bedside NN cord-015369-72cjogxz 1841 13 procedure procedure NN cord-015369-72cjogxz 1841 14 that that WDT cord-015369-72cjogxz 1841 15 resolves resolve VBZ cord-015369-72cjogxz 1841 16 ALs ALs NNP cord-015369-72cjogxz 1841 17 for for IN cord-015369-72cjogxz 1841 18 several several JJ cord-015369-72cjogxz 1841 19 months month NNS cord-015369-72cjogxz 1841 20 and and CC cord-015369-72cjogxz 1841 21 allows allow VBZ cord-015369-72cjogxz 1841 22 for for IN cord-015369-72cjogxz 1841 23 recovery recovery NN cord-015369-72cjogxz 1841 24 in in IN cord-015369-72cjogxz 1841 25 anticipation anticipation NN cord-015369-72cjogxz 1841 26 of of IN cord-015369-72cjogxz 1841 27 LT LT NNP cord-015369-72cjogxz 1841 28 and and CC cord-015369-72cjogxz 1841 29 definitive definitive JJ cord-015369-72cjogxz 1841 30 repair repair NN cord-015369-72cjogxz 1841 31 . . . cord-015369-72cjogxz 1842 1 Background background NN cord-015369-72cjogxz 1842 2 . . . cord-015369-72cjogxz 1843 1 Laparoscopic laparoscopic JJ cord-015369-72cjogxz 1843 2 live live JJ cord-015369-72cjogxz 1843 3 donor donor NN cord-015369-72cjogxz 1843 4 nephrectomy nephrectomy NN cord-015369-72cjogxz 1843 5 requires require VBZ cord-015369-72cjogxz 1843 6 meticulous meticulous JJ cord-015369-72cjogxz 1843 7 dissection dissection NN cord-015369-72cjogxz 1843 8 . . . cord-015369-72cjogxz 1844 1 Therefore therefore RB cord-015369-72cjogxz 1844 2 we -PRON- PRP cord-015369-72cjogxz 1844 3 have have VBP cord-015369-72cjogxz 1844 4 tested test VBN cord-015369-72cjogxz 1844 5 the the DT cord-015369-72cjogxz 1844 6 Endosite Endosite NNP cord-015369-72cjogxz 1844 7 3Di 3di NN cord-015369-72cjogxz 1844 8 Digital Digital NNP cord-015369-72cjogxz 1844 9 Vision Vision NNP cord-015369-72cjogxz 1844 10 System System NNP cord-015369-72cjogxz 1844 11 ( ( -LRB- cord-015369-72cjogxz 1844 12 Viking Viking NNP cord-015369-72cjogxz 1844 13 Systems Systems NNPS cord-015369-72cjogxz 1844 14 + + CC cord-015369-72cjogxz 1844 15 , , , cord-015369-72cjogxz 1844 16 Biomedica Biomedica NNP cord-015369-72cjogxz 1844 17 , , , cord-015369-72cjogxz 1844 18 Vienna Vienna NNP cord-015369-72cjogxz 1844 19 ) ) -RRB- cord-015369-72cjogxz 1844 20 for for IN cord-015369-72cjogxz 1844 21 applicability applicability NN cord-015369-72cjogxz 1844 22 , , , cord-015369-72cjogxz 1844 23 ergonomic ergonomic JJ cord-015369-72cjogxz 1844 24 aspects aspect NNS cord-015369-72cjogxz 1844 25 and and CC cord-015369-72cjogxz 1844 26 improved improve VBN cord-015369-72cjogxz 1844 27 spectral spectral JJ cord-015369-72cjogxz 1844 28 depth depth NN cord-015369-72cjogxz 1844 29 perception perception NN cord-015369-72cjogxz 1844 30 in in IN cord-015369-72cjogxz 1844 31 live live JJ cord-015369-72cjogxz 1844 32 laparoscopic laparoscopic JJ cord-015369-72cjogxz 1844 33 donor donor NN cord-015369-72cjogxz 1844 34 nephrectomy nephrectomy NN cord-015369-72cjogxz 1844 35 . . . cord-015369-72cjogxz 1845 1 Methods method NNS cord-015369-72cjogxz 1845 2 . . . cord-015369-72cjogxz 1846 1 The the DT cord-015369-72cjogxz 1846 2 3-dimensional 3-dimensional CD cord-015369-72cjogxz 1846 3 visualisation visualisation NN cord-015369-72cjogxz 1846 4 system system NN cord-015369-72cjogxz 1846 5 combined combine VBN cord-015369-72cjogxz 1846 6 with with IN cord-015369-72cjogxz 1846 7 high high JJ cord-015369-72cjogxz 1846 8 definition definition NN cord-015369-72cjogxz 1846 9 head head NN cord-015369-72cjogxz 1846 10 displays display NNS cord-015369-72cjogxz 1846 11 ( ( -LRB- cord-015369-72cjogxz 1846 12 Viking Viking NNP cord-015369-72cjogxz 1846 13 + + SYM cord-015369-72cjogxz 1846 14 , , , cord-015369-72cjogxz 1846 15 Biomedica Biomedica NNP cord-015369-72cjogxz 1846 16 , , , cord-015369-72cjogxz 1846 17 Vienna Vienna NNP cord-015369-72cjogxz 1846 18 ) ) -RRB- cord-015369-72cjogxz 1846 19 was be VBD cord-015369-72cjogxz 1846 20 used use VBN cord-015369-72cjogxz 1846 21 for for IN cord-015369-72cjogxz 1846 22 2 2 CD cord-015369-72cjogxz 1846 23 live live JJ cord-015369-72cjogxz 1846 24 donor donor NN cord-015369-72cjogxz 1846 25 uretero uretero NNS cord-015369-72cjogxz 1846 26 - - HYPH cord-015369-72cjogxz 1846 27 nephrectomies nephrectomy NNS cord-015369-72cjogxz 1846 28 in in IN cord-015369-72cjogxz 1846 29 2 2 CD cord-015369-72cjogxz 1846 30 patients patient NNS cord-015369-72cjogxz 1846 31 . . . cord-015369-72cjogxz 1847 1 Side side NN cord-015369-72cjogxz 1847 2 of of IN cord-015369-72cjogxz 1847 3 nephrectomy nephrectomy NN cord-015369-72cjogxz 1847 4 was be VBD cord-015369-72cjogxz 1847 5 chosen choose VBN cord-015369-72cjogxz 1847 6 according accord VBG cord-015369-72cjogxz 1847 7 to to IN cord-015369-72cjogxz 1847 8 selective selective JJ cord-015369-72cjogxz 1847 9 renal renal JJ cord-015369-72cjogxz 1847 10 function function NN cord-015369-72cjogxz 1847 11 and and CC cord-015369-72cjogxz 1847 12 vascular vascular JJ cord-015369-72cjogxz 1847 13 anatomy anatomy NN cord-015369-72cjogxz 1847 14 ( ( -LRB- cord-015369-72cjogxz 1847 15 right right JJ cord-015369-72cjogxz 1847 16 side side NN cord-015369-72cjogxz 1847 17 , , , cord-015369-72cjogxz 1847 18 n n NN cord-015369-72cjogxz 1847 19 ¼ ¼ NNP cord-015369-72cjogxz 1847 20 1 1 CD cord-015369-72cjogxz 1847 21 and and CC cord-015369-72cjogxz 1847 22 left leave VBD cord-015369-72cjogxz 1847 23 side side NN cord-015369-72cjogxz 1847 24 , , , cord-015369-72cjogxz 1847 25 n n NN cord-015369-72cjogxz 1847 26 ¼ ¼ NNP cord-015369-72cjogxz 1847 27 1 1 CD cord-015369-72cjogxz 1847 28 ) ) -RRB- cord-015369-72cjogxz 1847 29 . . . cord-015369-72cjogxz 1848 1 Standard standard JJ cord-015369-72cjogxz 1848 2 laparoscopic laparoscopic JJ cord-015369-72cjogxz 1848 3 access access NN cord-015369-72cjogxz 1848 4 was be VBD cord-015369-72cjogxz 1848 5 gained gain VBN cord-015369-72cjogxz 1848 6 through through IN cord-015369-72cjogxz 1848 7 4 4 CD cord-015369-72cjogxz 1848 8 trokars trokar NNS cord-015369-72cjogxz 1848 9 . . . cord-015369-72cjogxz 1849 1 For for IN cord-015369-72cjogxz 1849 2 the the DT cord-015369-72cjogxz 1849 3 left left JJ cord-015369-72cjogxz 1849 4 side side NN cord-015369-72cjogxz 1849 5 , , , cord-015369-72cjogxz 1849 6 vessels vessel NNS cord-015369-72cjogxz 1849 7 were be VBD cord-015369-72cjogxz 1849 8 clipped clip VBN cord-015369-72cjogxz 1849 9 and and CC cord-015369-72cjogxz 1849 10 transsected transsecte VBN cord-015369-72cjogxz 1849 11 laparoscopically laparoscopically RB cord-015369-72cjogxz 1849 12 . . . cord-015369-72cjogxz 1850 1 In in IN cord-015369-72cjogxz 1850 2 order order NN cord-015369-72cjogxz 1850 3 to to TO cord-015369-72cjogxz 1850 4 gain gain VB cord-015369-72cjogxz 1850 5 length length NN cord-015369-72cjogxz 1850 6 of of IN cord-015369-72cjogxz 1850 7 the the DT cord-015369-72cjogxz 1850 8 renal renal JJ cord-015369-72cjogxz 1850 9 vein vein NN cord-015369-72cjogxz 1850 10 on on IN cord-015369-72cjogxz 1850 11 the the DT cord-015369-72cjogxz 1850 12 right right JJ cord-015369-72cjogxz 1850 13 side side NN cord-015369-72cjogxz 1850 14 the the DT cord-015369-72cjogxz 1850 15 graft graft NN cord-015369-72cjogxz 1850 16 was be VBD cord-015369-72cjogxz 1850 17 retrieved retrieve VBN cord-015369-72cjogxz 1850 18 in in IN cord-015369-72cjogxz 1850 19 a a DT cord-015369-72cjogxz 1850 20 ' ' `` cord-015369-72cjogxz 1850 21 ' ' `` cord-015369-72cjogxz 1850 22 semi semi JJ cord-015369-72cjogxz 1850 23 - - JJ cord-015369-72cjogxz 1850 24 open open JJ cord-015369-72cjogxz 1850 25 ' ' '' cord-015369-72cjogxz 1850 26 ' ' '' cord-015369-72cjogxz 1850 27 fashion fashion NN cord-015369-72cjogxz 1850 28 as as IN cord-015369-72cjogxz 1850 29 described describe VBN cord-015369-72cjogxz 1850 30 previously previously RB cord-015369-72cjogxz 1850 31 by by IN cord-015369-72cjogxz 1850 32 our -PRON- PRP$ cord-015369-72cjogxz 1850 33 group group NN cord-015369-72cjogxz 1850 34 . . . cord-015369-72cjogxz 1851 1 Results result NNS cord-015369-72cjogxz 1851 2 . . . cord-015369-72cjogxz 1852 1 Mean mean JJ cord-015369-72cjogxz 1852 2 age age NN cord-015369-72cjogxz 1852 3 of of IN cord-015369-72cjogxz 1852 4 the the DT cord-015369-72cjogxz 1852 5 2 2 CD cord-015369-72cjogxz 1852 6 female female JJ cord-015369-72cjogxz 1852 7 patients patient NNS cord-015369-72cjogxz 1852 8 was be VBD cord-015369-72cjogxz 1852 9 41 41 CD cord-015369-72cjogxz 1852 10 AE AE NNP cord-015369-72cjogxz 1852 11 6 6 CD cord-015369-72cjogxz 1852 12 years year NNS cord-015369-72cjogxz 1852 13 . . . cord-015369-72cjogxz 1853 1 Mean mean JJ cord-015369-72cjogxz 1853 2 operation operation NN cord-015369-72cjogxz 1853 3 time time NN cord-015369-72cjogxz 1853 4 , , , cord-015369-72cjogxz 1853 5 warm warm JJ cord-015369-72cjogxz 1853 6 ischemia ischemia NN cord-015369-72cjogxz 1853 7 time time NN cord-015369-72cjogxz 1853 8 and and CC cord-015369-72cjogxz 1853 9 length length NN cord-015369-72cjogxz 1853 10 of of IN cord-015369-72cjogxz 1853 11 hospital hospital NN cord-015369-72cjogxz 1853 12 stay stay NN cord-015369-72cjogxz 1853 13 were be VBD cord-015369-72cjogxz 1853 14 242 242 CD cord-015369-72cjogxz 1853 15 AE AE NNP cord-015369-72cjogxz 1853 16 3 3 CD cord-015369-72cjogxz 1853 17 min min NN cord-015369-72cjogxz 1853 18 . . . cord-015369-72cjogxz 1854 1 , , , cord-015369-72cjogxz 1854 2 3 3 CD cord-015369-72cjogxz 1854 3 AE AE NNP cord-015369-72cjogxz 1854 4 1 1 CD cord-015369-72cjogxz 1854 5 min min NN cord-015369-72cjogxz 1854 6 . . . cord-015369-72cjogxz 1854 7 and and CC cord-015369-72cjogxz 1854 8 7.5 7.5 CD cord-015369-72cjogxz 1854 9 AE AE NNP cord-015369-72cjogxz 1854 10 0.5 0.5 CD cord-015369-72cjogxz 1854 11 days day NNS cord-015369-72cjogxz 1854 12 . . . cord-015369-72cjogxz 1855 1 Upon upon IN cord-015369-72cjogxz 1855 2 discharge discharge NN cord-015369-72cjogxz 1855 3 , , , cord-015369-72cjogxz 1855 4 creatinine creatinine NN cord-015369-72cjogxz 1855 5 levels level NNS cord-015369-72cjogxz 1855 6 , , , cord-015369-72cjogxz 1855 7 urea urea NN cord-015369-72cjogxz 1855 8 and and CC cord-015369-72cjogxz 1855 9 c c NN cord-015369-72cjogxz 1855 10 - - HYPH cord-015369-72cjogxz 1855 11 reactive reactive JJ cord-015369-72cjogxz 1855 12 protein protein NN cord-015369-72cjogxz 1855 13 levels level NNS cord-015369-72cjogxz 1855 14 were be VBD cord-015369-72cjogxz 1855 15 0.98 0.98 CD cord-015369-72cjogxz 1855 16 AE AE NNP cord-015369-72cjogxz 1855 17 0.03 0.03 CD cord-015369-72cjogxz 1855 18 mg mg NNP cord-015369-72cjogxz 1855 19 / / SYM cord-015369-72cjogxz 1855 20 dl dl NNP cord-015369-72cjogxz 1855 21 , , , cord-015369-72cjogxz 1855 22 26.1 26.1 CD cord-015369-72cjogxz 1855 23 AE AE NNP cord-015369-72cjogxz 1855 24 3.5 3.5 CD cord-015369-72cjogxz 1855 25 mg mg NNP cord-015369-72cjogxz 1855 26 / / SYM cord-015369-72cjogxz 1855 27 dl dl NNP cord-015369-72cjogxz 1855 28 and and CC cord-015369-72cjogxz 1855 29 2.37 2.37 CD cord-015369-72cjogxz 1855 30 AE AE NNP cord-015369-72cjogxz 1855 31 0.63 0.63 CD cord-015369-72cjogxz 1855 32 mg mg NNP cord-015369-72cjogxz 1855 33 / / SYM cord-015369-72cjogxz 1855 34 dl dl NNP cord-015369-72cjogxz 1855 35 , , , cord-015369-72cjogxz 1855 36 respectively respectively RB cord-015369-72cjogxz 1855 37 . . . cord-015369-72cjogxz 1856 1 There there EX cord-015369-72cjogxz 1856 2 was be VBD cord-015369-72cjogxz 1856 3 no no DT cord-015369-72cjogxz 1856 4 major major JJ cord-015369-72cjogxz 1856 5 complication complication NN cord-015369-72cjogxz 1856 6 or or CC cord-015369-72cjogxz 1856 7 any any DT cord-015369-72cjogxz 1856 8 procedure procedure NN cord-015369-72cjogxz 1856 9 related relate VBN cord-015369-72cjogxz 1856 10 morbidity morbidity NN cord-015369-72cjogxz 1856 11 such such JJ cord-015369-72cjogxz 1856 12 as as IN cord-015369-72cjogxz 1856 13 infections infection NNS cord-015369-72cjogxz 1856 14 or or CC cord-015369-72cjogxz 1856 15 postoperative postoperative JJ cord-015369-72cjogxz 1856 16 lymphatic lymphatic JJ cord-015369-72cjogxz 1856 17 leaks leak NNS cord-015369-72cjogxz 1856 18 . . . cord-015369-72cjogxz 1857 1 Conclusions conclusion NNS cord-015369-72cjogxz 1857 2 . . . cord-015369-72cjogxz 1858 1 The the DT cord-015369-72cjogxz 1858 2 3-D 3-d JJ cord-015369-72cjogxz 1858 3 laparoscopic laparoscopic JJ cord-015369-72cjogxz 1858 4 system system NN cord-015369-72cjogxz 1858 5 offers offer VBZ cord-015369-72cjogxz 1858 6 ergonomic ergonomic JJ cord-015369-72cjogxz 1858 7 advantages advantage NNS cord-015369-72cjogxz 1858 8 and and CC cord-015369-72cjogxz 1858 9 improved improve VBN cord-015369-72cjogxz 1858 10 spectral spectral JJ cord-015369-72cjogxz 1858 11 depth depth NN cord-015369-72cjogxz 1858 12 perception perception NN cord-015369-72cjogxz 1858 13 particularly particularly RB cord-015369-72cjogxz 1858 14 in in IN cord-015369-72cjogxz 1858 15 complex complex JJ cord-015369-72cjogxz 1858 16 laparoscopic laparoscopic JJ cord-015369-72cjogxz 1858 17 procedures procedure NNS cord-015369-72cjogxz 1858 18 like like IN cord-015369-72cjogxz 1858 19 live live JJ cord-015369-72cjogxz 1858 20 donor donor NN cord-015369-72cjogxz 1858 21 nephrectomy nephrectomy NN cord-015369-72cjogxz 1858 22 . . . cord-015369-72cjogxz 1859 1 This this DT cord-015369-72cjogxz 1859 2 system system NN cord-015369-72cjogxz 1859 3 couples couple VBZ cord-015369-72cjogxz 1859 4 3-D 3-d JJ cord-015369-72cjogxz 1859 5 visualisation visualisation NN cord-015369-72cjogxz 1859 6 with with IN cord-015369-72cjogxz 1859 7 traditional traditional JJ cord-015369-72cjogxz 1859 8 laparoscopy laparoscopy NN cord-015369-72cjogxz 1859 9 thus thus RB cord-015369-72cjogxz 1859 10 offering offer VBG cord-015369-72cjogxz 1859 11 ergonomic ergonomic JJ cord-015369-72cjogxz 1859 12 advantages advantage NNS cord-015369-72cjogxz 1859 13 for for IN cord-015369-72cjogxz 1859 14 less less JJR cord-015369-72cjogxz 1859 15 than than IN cord-015369-72cjogxz 1859 16 one one CD cord-015369-72cjogxz 1859 17 - - HYPH cord-015369-72cjogxz 1859 18 tenth tenth NN cord-015369-72cjogxz 1859 19 the the DT cord-015369-72cjogxz 1859 20 cost cost NN cord-015369-72cjogxz 1859 21 of of IN cord-015369-72cjogxz 1859 22 the the DT cord-015369-72cjogxz 1859 23 Da Da NNP cord-015369-72cjogxz 1859 24 Vinci Vinci NNP cord-015369-72cjogxz 1859 25 System System NNP cord-015369-72cjogxz 1859 26 which which WDT cord-015369-72cjogxz 1859 27 may may MD cord-015369-72cjogxz 1859 28 be be VB cord-015369-72cjogxz 1859 29 of of IN cord-015369-72cjogxz 1859 30 significant significant JJ cord-015369-72cjogxz 1859 31 importance importance NN cord-015369-72cjogxz 1859 32 for for IN cord-015369-72cjogxz 1859 33 the the DT cord-015369-72cjogxz 1859 34 broad broad JJ cord-015369-72cjogxz 1859 35 spectrum spectrum NN cord-015369-72cjogxz 1859 36 of of IN cord-015369-72cjogxz 1859 37 minimally minimally RB cord-015369-72cjogxz 1859 38 invasive invasive JJ cord-015369-72cjogxz 1859 39 surgery surgery NN cord-015369-72cjogxz 1859 40 . . . cord-015369-72cjogxz 1860 1 Background background NN cord-015369-72cjogxz 1860 2 . . . cord-015369-72cjogxz 1861 1 Obesity obesity NN cord-015369-72cjogxz 1861 2 and and CC cord-015369-72cjogxz 1861 3 vascular vascular JJ cord-015369-72cjogxz 1861 4 anomalies anomaly NNS cord-015369-72cjogxz 1861 5 have have VBP cord-015369-72cjogxz 1861 6 been be VBN cord-015369-72cjogxz 1861 7 considered consider VBN cord-015369-72cjogxz 1861 8 relative relative JJ cord-015369-72cjogxz 1861 9 contraindications contraindication NNS cord-015369-72cjogxz 1861 10 for for IN cord-015369-72cjogxz 1861 11 living live VBG cord-015369-72cjogxz 1861 12 donor donor NN cord-015369-72cjogxz 1861 13 kidney kidney NN cord-015369-72cjogxz 1861 14 transplantation transplantation NN cord-015369-72cjogxz 1861 15 . . . cord-015369-72cjogxz 1862 1 However however RB cord-015369-72cjogxz 1862 2 , , , cord-015369-72cjogxz 1862 3 successful successful JJ cord-015369-72cjogxz 1862 4 transplantation transplantation NN cord-015369-72cjogxz 1862 5 of of IN cord-015369-72cjogxz 1862 6 laparoscopically laparoscopically RB cord-015369-72cjogxz 1862 7 retrieved retrieve VBN cord-015369-72cjogxz 1862 8 kidneys kidney NNS cord-015369-72cjogxz 1862 9 with with IN cord-015369-72cjogxz 1862 10 accessory accessory JJ cord-015369-72cjogxz 1862 11 renal renal JJ cord-015369-72cjogxz 1862 12 vessels vessel NNS cord-015369-72cjogxz 1862 13 incidentially incidentially RB cord-015369-72cjogxz 1862 14 found find VBD cord-015369-72cjogxz 1862 15 upon upon IN cord-015369-72cjogxz 1862 16 operation operation NN cord-015369-72cjogxz 1862 17 , , , cord-015369-72cjogxz 1862 18 increasing increase VBG cord-015369-72cjogxz 1862 19 body body NN cord-015369-72cjogxz 1862 20 mass mass NN cord-015369-72cjogxz 1862 21 index index NN cord-015369-72cjogxz 1862 22 ( ( -LRB- cord-015369-72cjogxz 1862 23 BMI BMI NNP cord-015369-72cjogxz 1862 24 ) ) -RRB- cord-015369-72cjogxz 1862 25 and and CC cord-015369-72cjogxz 1862 26 donor donor NN cord-015369-72cjogxz 1862 27 age age NN cord-015369-72cjogxz 1862 28 rise rise VBP cord-015369-72cjogxz 1862 29 the the DT cord-015369-72cjogxz 1862 30 question question NN cord-015369-72cjogxz 1862 31 for for IN cord-015369-72cjogxz 1862 32 the the DT cord-015369-72cjogxz 1862 33 limits limit NNS cord-015369-72cjogxz 1862 34 of of IN cord-015369-72cjogxz 1862 35 live live JJ cord-015369-72cjogxz 1862 36 donation donation NN cord-015369-72cjogxz 1862 37 . . . cord-015369-72cjogxz 1863 1 Methods Methods NNPS cord-015369-72cjogxz 1863 2 Conclusions conclusion NNS cord-015369-72cjogxz 1863 3 . . . cord-015369-72cjogxz 1864 1 Although although IN cord-015369-72cjogxz 1864 2 a a DT cord-015369-72cjogxz 1864 3 significant significant JJ cord-015369-72cjogxz 1864 4 proportion proportion NN cord-015369-72cjogxz 1864 5 of of IN cord-015369-72cjogxz 1864 6 patients patient NNS cord-015369-72cjogxz 1864 7 in in IN cord-015369-72cjogxz 1864 8 our -PRON- PRP$ cord-015369-72cjogxz 1864 9 series series NN cord-015369-72cjogxz 1864 10 qualifiy qualifiy NNP cord-015369-72cjogxz 1864 11 as as IN cord-015369-72cjogxz 1864 12 ' ' '' cord-015369-72cjogxz 1864 13 ' ' `` cord-015369-72cjogxz 1864 14 marginal marginal JJ cord-015369-72cjogxz 1864 15 donors donor NNS cord-015369-72cjogxz 1864 16 ' ' POS cord-015369-72cjogxz 1864 17 ' ' '' cord-015369-72cjogxz 1864 18 LLDN LLDN NNP cord-015369-72cjogxz 1864 19 is be VBZ cord-015369-72cjogxz 1864 20 feasable feasable JJ cord-015369-72cjogxz 1864 21 and and CC cord-015369-72cjogxz 1864 22 safe safe JJ cord-015369-72cjogxz 1864 23 . . . cord-015369-72cjogxz 1865 1 However however RB cord-015369-72cjogxz 1865 2 , , , cord-015369-72cjogxz 1865 3 adapted adapt VBD cord-015369-72cjogxz 1865 4 surgical surgical JJ cord-015369-72cjogxz 1865 5 technique technique NN cord-015369-72cjogxz 1865 6 and and CC cord-015369-72cjogxz 1865 7 careful careful JJ cord-015369-72cjogxz 1865 8 monitoring monitoring NN cord-015369-72cjogxz 1865 9 of of IN cord-015369-72cjogxz 1865 10 postoperative postoperative JJ cord-015369-72cjogxz 1865 11 renal renal JJ cord-015369-72cjogxz 1865 12 function function NN cord-015369-72cjogxz 1865 13 is be VBZ cord-015369-72cjogxz 1865 14 mandatory mandatory JJ cord-015369-72cjogxz 1865 15 in in IN cord-015369-72cjogxz 1865 16 these these DT cord-015369-72cjogxz 1865 17 patients patient NNS cord-015369-72cjogxz 1865 18 . . . cord-015369-72cjogxz 1866 1 Clinical clinical JJ cord-015369-72cjogxz 1866 2 feasibility feasibility NN cord-015369-72cjogxz 1866 3 of of IN cord-015369-72cjogxz 1866 4 a a DT cord-015369-72cjogxz 1866 5 new new JJ cord-015369-72cjogxz 1866 6 colonic colonic JJ cord-015369-72cjogxz 1866 7 access access NN cord-015369-72cjogxz 1866 8 device device NN cord-015369-72cjogxz 1866 9 ( ( -LRB- cord-015369-72cjogxz 1866 10 Megachannel Megachannel NNP cord-015369-72cjogxz 1866 11 TM TM NNP cord-015369-72cjogxz 1866 12 ) ) -RRB- cord-015369-72cjogxz 1866 13 for for IN cord-015369-72cjogxz 1866 14 interventional interventional JJ cord-015369-72cjogxz 1866 15 procedures procedure NNS cord-015369-72cjogxz 1866 16 at at IN cord-015369-72cjogxz 1866 17 colonoscopy colonoscopy NN cord-015369-72cjogxz 1866 18 : : : cord-015369-72cjogxz 1866 19 a a DT cord-015369-72cjogxz 1866 20 prospective prospective JJ cord-015369-72cjogxz 1866 21 , , , cord-015369-72cjogxz 1866 22 multicenter multicenter JJ cord-015369-72cjogxz 1866 23 trial trial NN cord-015369-72cjogxz 1866 24 Background Background NNP cord-015369-72cjogxz 1866 25 . . . cord-015369-72cjogxz 1867 1 Megachannel Megachannel NNP cord-015369-72cjogxz 1867 2 TM TM NNP cord-015369-72cjogxz 1867 3 is be VBZ cord-015369-72cjogxz 1867 4 a a DT cord-015369-72cjogxz 1867 5 new new JJ cord-015369-72cjogxz 1867 6 colonic colonic JJ cord-015369-72cjogxz 1867 7 access access NN cord-015369-72cjogxz 1867 8 system system NN cord-015369-72cjogxz 1867 9 that that WDT cord-015369-72cjogxz 1867 10 was be VBD cord-015369-72cjogxz 1867 11 originally originally RB cord-015369-72cjogxz 1867 12 developed develop VBN cord-015369-72cjogxz 1867 13 for for IN cord-015369-72cjogxz 1867 14 colonoscopic colonoscopic JJ cord-015369-72cjogxz 1867 15 appendectomy appendectomy NN cord-015369-72cjogxz 1867 16 . . . cord-015369-72cjogxz 1868 1 Once once RB cord-015369-72cjogxz 1868 2 in in IN cord-015369-72cjogxz 1868 3 place place NN cord-015369-72cjogxz 1868 4 , , , cord-015369-72cjogxz 1868 5 the the DT cord-015369-72cjogxz 1868 6 channel channel NN cord-015369-72cjogxz 1868 7 protects protect VBZ cord-015369-72cjogxz 1868 8 the the DT cord-015369-72cjogxz 1868 9 colon colon NN cord-015369-72cjogxz 1868 10 from from IN cord-015369-72cjogxz 1868 11 perforation perforation NN cord-015369-72cjogxz 1868 12 risks risk NNS cord-015369-72cjogxz 1868 13 during during IN cord-015369-72cjogxz 1868 14 rapid rapid JJ cord-015369-72cjogxz 1868 15 , , , cord-015369-72cjogxz 1868 16 multiple multiple JJ cord-015369-72cjogxz 1868 17 passes pass NNS cord-015369-72cjogxz 1868 18 of of IN cord-015369-72cjogxz 1868 19 the the DT cord-015369-72cjogxz 1868 20 colonoscope colonoscope NN cord-015369-72cjogxz 1868 21 to to IN cord-015369-72cjogxz 1868 22 the the DT cord-015369-72cjogxz 1868 23 right right JJ cord-015369-72cjogxz 1868 24 colon colon NN cord-015369-72cjogxz 1868 25 . . . cord-015369-72cjogxz 1869 1 The the DT cord-015369-72cjogxz 1869 2 20 20 CD cord-015369-72cjogxz 1869 3 mm mm NNP cord-015369-72cjogxz 1869 4 working working NN cord-015369-72cjogxz 1869 5 channel channel NN cord-015369-72cjogxz 1869 6 allows allow VBZ cord-015369-72cjogxz 1869 7 rapid rapid JJ cord-015369-72cjogxz 1869 8 and and CC cord-015369-72cjogxz 1869 9 safe safe JJ cord-015369-72cjogxz 1869 10 delivery delivery NN cord-015369-72cjogxz 1869 11 of of IN cord-015369-72cjogxz 1869 12 bulky bulky JJ cord-015369-72cjogxz 1869 13 instruments instrument NNS cord-015369-72cjogxz 1869 14 , , , cord-015369-72cjogxz 1869 15 as as IN cord-015369-72cjogxz 1869 16 the the DT cord-015369-72cjogxz 1869 17 removal removal NN cord-015369-72cjogxz 1869 18 of of IN cord-015369-72cjogxz 1869 19 large large JJ cord-015369-72cjogxz 1869 20 specimens specimen NNS cord-015369-72cjogxz 1869 21 . . . cord-015369-72cjogxz 1870 1 Methods method NNS cord-015369-72cjogxz 1870 2 . . . cord-015369-72cjogxz 1871 1 The the DT cord-015369-72cjogxz 1871 2 device device NN cord-015369-72cjogxz 1871 3 ( ( -LRB- cord-015369-72cjogxz 1871 4 22 22 CD cord-015369-72cjogxz 1871 5 outer outer JJ cord-015369-72cjogxz 1871 6 diameter diameter NN cord-015369-72cjogxz 1871 7 , , , cord-015369-72cjogxz 1871 8 100 100 CD cord-015369-72cjogxz 1871 9 cm cm NNS cord-015369-72cjogxz 1871 10 in in IN cord-015369-72cjogxz 1871 11 length length NN cord-015369-72cjogxz 1871 12 ) ) -RRB- cord-015369-72cjogxz 1871 13 was be VBD cord-015369-72cjogxz 1871 14 constructed construct VBN cord-015369-72cjogxz 1871 15 of of IN cord-015369-72cjogxz 1871 16 a a DT cord-015369-72cjogxz 1871 17 wire wire NN cord-015369-72cjogxz 1871 18 reinforced reinforce VBN cord-015369-72cjogxz 1871 19 polyvinylchloride polyvinylchloride NN cord-015369-72cjogxz 1871 20 plastisol plastisol NN cord-015369-72cjogxz 1871 21 tube tube NN cord-015369-72cjogxz 1871 22 with with IN cord-015369-72cjogxz 1871 23 a a DT cord-015369-72cjogxz 1871 24 thermoplastic thermoplastic JJ cord-015369-72cjogxz 1871 25 distal distal JJ cord-015369-72cjogxz 1871 26 tip tip NN cord-015369-72cjogxz 1871 27 and and CC cord-015369-72cjogxz 1871 28 a a DT cord-015369-72cjogxz 1871 29 proximal proximal JJ cord-015369-72cjogxz 1871 30 hub hub NN cord-015369-72cjogxz 1871 31 with with IN cord-015369-72cjogxz 1871 32 integrated integrated JJ cord-015369-72cjogxz 1871 33 scope scope NN cord-015369-72cjogxz 1871 34 - - HYPH cord-015369-72cjogxz 1871 35 seal seal NN cord-015369-72cjogxz 1871 36 . . . cord-015369-72cjogxz 1872 1 A a DT cord-015369-72cjogxz 1872 2 rounded rounded JJ cord-015369-72cjogxz 1872 3 introducer introducer NN cord-015369-72cjogxz 1872 4 - - HYPH cord-015369-72cjogxz 1872 5 plug plug NN cord-015369-72cjogxz 1872 6 was be VBD cord-015369-72cjogxz 1872 7 fitted fit VBN cord-015369-72cjogxz 1872 8 onto onto IN cord-015369-72cjogxz 1872 9 the the DT cord-015369-72cjogxz 1872 10 distal distal JJ cord-015369-72cjogxz 1872 11 tip tip NN cord-015369-72cjogxz 1872 12 and and CC cord-015369-72cjogxz 1872 13 formed form VBD cord-015369-72cjogxz 1872 14 a a DT cord-015369-72cjogxz 1872 15 smooth smooth JJ cord-015369-72cjogxz 1872 16 solid solid JJ cord-015369-72cjogxz 1872 17 surface surface NN cord-015369-72cjogxz 1872 18 between between IN cord-015369-72cjogxz 1872 19 the the DT cord-015369-72cjogxz 1872 20 overtube overtube NN cord-015369-72cjogxz 1872 21 and and CC cord-015369-72cjogxz 1872 22 colonoscope colonoscope NN cord-015369-72cjogxz 1872 23 to to TO cord-015369-72cjogxz 1872 24 prevent prevent VB cord-015369-72cjogxz 1872 25 tissue tissue NN cord-015369-72cjogxz 1872 26 entrapment entrapment NN cord-015369-72cjogxz 1872 27 . . . cord-015369-72cjogxz 1873 1 Results result NNS cord-015369-72cjogxz 1873 2 . . . cord-015369-72cjogxz 1874 1 The the DT cord-015369-72cjogxz 1874 2 Megachannel Megachannel NNP cord-015369-72cjogxz 1874 3 TM TM NNP cord-015369-72cjogxz 1874 4 was be VBD cord-015369-72cjogxz 1874 5 applied apply VBN cord-015369-72cjogxz 1874 6 in in IN cord-015369-72cjogxz 1874 7 40 40 CD cord-015369-72cjogxz 1874 8 patients patient NNS cord-015369-72cjogxz 1874 9 undergoing undergo VBG cord-015369-72cjogxz 1874 10 colonoscopy colonoscopy NN cord-015369-72cjogxz 1874 11 . . . cord-015369-72cjogxz 1875 1 The the DT cord-015369-72cjogxz 1875 2 cecum cecum NN cord-015369-72cjogxz 1875 3 was be VBD cord-015369-72cjogxz 1875 4 reached reach VBN cord-015369-72cjogxz 1875 5 in in IN cord-015369-72cjogxz 1875 6 34/40 34/40 CD cord-015369-72cjogxz 1875 7 patients patient NNS cord-015369-72cjogxz 1875 8 within within IN cord-015369-72cjogxz 1875 9 16 16 CD cord-015369-72cjogxz 1875 10 min min NN cord-015369-72cjogxz 1875 11 , , , cord-015369-72cjogxz 1875 12 with with IN cord-015369-72cjogxz 1875 13 73 73 CD cord-015369-72cjogxz 1875 14 cm cm NNS cord-015369-72cjogxz 1875 15 ( ( -LRB- cord-015369-72cjogxz 1875 16 60 60 CD cord-015369-72cjogxz 1875 17 to to TO cord-015369-72cjogxz 1875 18 90 90 CD cord-015369-72cjogxz 1875 19 cm cm NNS cord-015369-72cjogxz 1875 20 ) ) -RRB- cord-015369-72cjogxz 1875 21 of of IN cord-015369-72cjogxz 1875 22 the the DT cord-015369-72cjogxz 1875 23 overtube overtube NN cord-015369-72cjogxz 1875 24 being be VBG cord-015369-72cjogxz 1875 25 inserted insert VBN cord-015369-72cjogxz 1875 26 into into IN cord-015369-72cjogxz 1875 27 the the DT cord-015369-72cjogxz 1875 28 colon colon NN cord-015369-72cjogxz 1875 29 . . . cord-015369-72cjogxz 1876 1 Mild mild JJ cord-015369-72cjogxz 1876 2 tissue tissue NN cord-015369-72cjogxz 1876 3 bruises bruise NNS cord-015369-72cjogxz 1876 4 were be VBD cord-015369-72cjogxz 1876 5 observed observe VBN cord-015369-72cjogxz 1876 6 in in IN cord-015369-72cjogxz 1876 7 9 9 CD cord-015369-72cjogxz 1876 8 patients patient NNS cord-015369-72cjogxz 1876 9 , , , cord-015369-72cjogxz 1876 10 mild mild JJ cord-015369-72cjogxz 1876 11 to to IN cord-015369-72cjogxz 1876 12 moderate moderate JJ cord-015369-72cjogxz 1876 13 pain pain NN cord-015369-72cjogxz 1876 14 in in IN cord-015369-72cjogxz 1876 15 5 5 CD cord-015369-72cjogxz 1876 16 patients patient NNS cord-015369-72cjogxz 1876 17 . . . cord-015369-72cjogxz 1877 1 In in IN cord-015369-72cjogxz 1877 2 7 7 CD cord-015369-72cjogxz 1877 3 patients patient NNS cord-015369-72cjogxz 1877 4 the the DT cord-015369-72cjogxz 1877 5 Megachannel Megachannel NNP cord-015369-72cjogxz 1877 6 assisted assist VBD cord-015369-72cjogxz 1877 7 the the DT cord-015369-72cjogxz 1877 8 removal removal NN cord-015369-72cjogxz 1877 9 of of IN cord-015369-72cjogxz 1877 10 multiple multiple JJ cord-015369-72cjogxz 1877 11 polyps polyp NNS cord-015369-72cjogxz 1877 12 . . . cord-015369-72cjogxz 1878 1 In in IN cord-015369-72cjogxz 1878 2 one one CD cord-015369-72cjogxz 1878 3 patient patient NN cord-015369-72cjogxz 1878 4 a a DT cord-015369-72cjogxz 1878 5 EUS eus NN cord-015369-72cjogxz 1878 6 scope scope NN cord-015369-72cjogxz 1878 7 was be VBD cord-015369-72cjogxz 1878 8 delivered deliver VBN cord-015369-72cjogxz 1878 9 for for IN cord-015369-72cjogxz 1878 10 evaluation evaluation NN cord-015369-72cjogxz 1878 11 of of IN cord-015369-72cjogxz 1878 12 tumor tumor NN cord-015369-72cjogxz 1878 13 wall wall NN cord-015369-72cjogxz 1878 14 infiltration infiltration NN cord-015369-72cjogxz 1878 15 before before IN cord-015369-72cjogxz 1878 16 submucosal submucosal NNP cord-015369-72cjogxz 1878 17 resection resection NN cord-015369-72cjogxz 1878 18 , , , cord-015369-72cjogxz 1878 19 in in IN cord-015369-72cjogxz 1878 20 another another DT cord-015369-72cjogxz 1878 21 patient patient NN cord-015369-72cjogxz 1878 22 a a DT cord-015369-72cjogxz 1878 23 suction suction NN cord-015369-72cjogxz 1878 24 cap cap NN cord-015369-72cjogxz 1878 25 was be VBD cord-015369-72cjogxz 1878 26 successfully successfully RB cord-015369-72cjogxz 1878 27 delivered deliver VBN cord-015369-72cjogxz 1878 28 to to IN cord-015369-72cjogxz 1878 29 the the DT cord-015369-72cjogxz 1878 30 right right JJ cord-015369-72cjogxz 1878 31 flexure flexure NN cord-015369-72cjogxz 1878 32 for for IN cord-015369-72cjogxz 1878 33 removal removal NN cord-015369-72cjogxz 1878 34 of of IN cord-015369-72cjogxz 1878 35 an an DT cord-015369-72cjogxz 1878 36 incomplete incomplete RB cord-015369-72cjogxz 1878 37 - - HYPH cord-015369-72cjogxz 1878 38 lifting lift VBG cord-015369-72cjogxz 1878 39 polyp polyp NN cord-015369-72cjogxz 1878 40 . . . cord-015369-72cjogxz 1879 1 Conclusions conclusion NNS cord-015369-72cjogxz 1879 2 . . . cord-015369-72cjogxz 1880 1 This this DT cord-015369-72cjogxz 1880 2 new new JJ cord-015369-72cjogxz 1880 3 colonic colonic JJ cord-015369-72cjogxz 1880 4 access access NN cord-015369-72cjogxz 1880 5 system system NN cord-015369-72cjogxz 1880 6 ( ( -LRB- cord-015369-72cjogxz 1880 7 Megachannel Megachannel NNP cord-015369-72cjogxz 1880 8 TM TM NNP cord-015369-72cjogxz 1880 9 ) ) -RRB- cord-015369-72cjogxz 1880 10 can can MD cord-015369-72cjogxz 1880 11 be be VB cord-015369-72cjogxz 1880 12 safely safely RB cord-015369-72cjogxz 1880 13 applied apply VBN cord-015369-72cjogxz 1880 14 into into IN cord-015369-72cjogxz 1880 15 the the DT cord-015369-72cjogxz 1880 16 right right JJ cord-015369-72cjogxz 1880 17 colon colon NN cord-015369-72cjogxz 1880 18 and and CC cord-015369-72cjogxz 1880 19 is be VBZ cord-015369-72cjogxz 1880 20 useful useful JJ cord-015369-72cjogxz 1880 21 for for IN cord-015369-72cjogxz 1880 22 a a DT cord-015369-72cjogxz 1880 23 variety variety NN cord-015369-72cjogxz 1880 24 of of IN cord-015369-72cjogxz 1880 25 colonic colonic JJ cord-015369-72cjogxz 1880 26 interventions intervention NNS cord-015369-72cjogxz 1880 27 that that WDT cord-015369-72cjogxz 1880 28 require require VBP cord-015369-72cjogxz 1880 29 multiple multiple JJ cord-015369-72cjogxz 1880 30 insertion insertion NN cord-015369-72cjogxz 1880 31 of of IN cord-015369-72cjogxz 1880 32 the the DT cord-015369-72cjogxz 1880 33 scope scope NN cord-015369-72cjogxz 1880 34 or or CC cord-015369-72cjogxz 1880 35 delivery delivery NN cord-015369-72cjogxz 1880 36 of of IN cord-015369-72cjogxz 1880 37 bulky bulky JJ cord-015369-72cjogxz 1880 38 instruments instrument NNS cord-015369-72cjogxz 1880 39 . . . cord-015369-72cjogxz 1881 1 This this DT cord-015369-72cjogxz 1881 2 instrument instrument NN cord-015369-72cjogxz 1881 3 might may MD cord-015369-72cjogxz 1881 4 support support VB cord-015369-72cjogxz 1881 5 NOTES note NNS cord-015369-72cjogxz 1881 6 procedures procedure NNS cord-015369-72cjogxz 1881 7 and and CC cord-015369-72cjogxz 1881 8 removal removal NN cord-015369-72cjogxz 1881 9 of of IN cord-015369-72cjogxz 1881 10 colonic colonic JJ cord-015369-72cjogxz 1881 11 stents stent NNS cord-015369-72cjogxz 1881 12 . . . cord-015369-72cjogxz 1882 1 Fast fast JJ cord-015369-72cjogxz 1882 2 track track NN cord-015369-72cjogxz 1882 3 surgery surgery NN cord-015369-72cjogxz 1882 4 in in IN cord-015369-72cjogxz 1882 5 acute acute JJ cord-015369-72cjogxz 1882 6 ileus ileus NN cord-015369-72cjogxz 1883 1 -first -first WDT cord-015369-72cjogxz 1883 2 results result VBZ cord-015369-72cjogxz 1883 3 Background Background NNP cord-015369-72cjogxz 1883 4 . . . cord-015369-72cjogxz 1884 1 Fast Fast NNP cord-015369-72cjogxz 1884 2 Track Track NNP cord-015369-72cjogxz 1884 3 Rehabilitation Rehabilitation NNP cord-015369-72cjogxz 1884 4 ( ( -LRB- cord-015369-72cjogxz 1884 5 FTR FTR NNP cord-015369-72cjogxz 1884 6 ) ) -RRB- cord-015369-72cjogxz 1884 7 is be VBZ cord-015369-72cjogxz 1884 8 well well RB cord-015369-72cjogxz 1884 9 established establish VBN cord-015369-72cjogxz 1884 10 in in IN cord-015369-72cjogxz 1884 11 elective elective JJ cord-015369-72cjogxz 1884 12 surgery surgery NN cord-015369-72cjogxz 1884 13 , , , cord-015369-72cjogxz 1884 14 but but CC cord-015369-72cjogxz 1884 15 there there EX cord-015369-72cjogxz 1884 16 is be VBZ cord-015369-72cjogxz 1884 17 little little JJ cord-015369-72cjogxz 1884 18 experience experience NN cord-015369-72cjogxz 1884 19 with with IN cord-015369-72cjogxz 1884 20 this this DT cord-015369-72cjogxz 1884 21 concept concept NN cord-015369-72cjogxz 1884 22 in in IN cord-015369-72cjogxz 1884 23 emergency emergency NN cord-015369-72cjogxz 1884 24 colorectal colorectal JJ cord-015369-72cjogxz 1884 25 surgery surgery NN cord-015369-72cjogxz 1884 26 . . . cord-015369-72cjogxz 1885 1 We -PRON- PRP cord-015369-72cjogxz 1885 2 present present VBP cord-015369-72cjogxz 1885 3 our -PRON- PRP$ cord-015369-72cjogxz 1885 4 data datum NNS cord-015369-72cjogxz 1885 5 of of IN cord-015369-72cjogxz 1885 6 application application NN cord-015369-72cjogxz 1885 7 of of IN cord-015369-72cjogxz 1885 8 FTR FTR NNP cord-015369-72cjogxz 1885 9 in in IN cord-015369-72cjogxz 1885 10 patients patient NNS cord-015369-72cjogxz 1885 11 with with IN cord-015369-72cjogxz 1885 12 acute acute JJ cord-015369-72cjogxz 1885 13 ileus ileus NN cord-015369-72cjogxz 1885 14 . . . cord-015369-72cjogxz 1886 1 Methods method NNS cord-015369-72cjogxz 1886 2 . . . cord-015369-72cjogxz 1887 1 644 644 CD cord-015369-72cjogxz 1887 2 Patient Patient NNP cord-015369-72cjogxz 1887 3 were be VBD cord-015369-72cjogxz 1887 4 included include VBN cord-015369-72cjogxz 1887 5 prospectively prospectively RB cord-015369-72cjogxz 1887 6 , , , cord-015369-72cjogxz 1887 7 64 64 CD cord-015369-72cjogxz 1887 8 ( ( -LRB- cord-015369-72cjogxz 1887 9 9.6 9.6 CD cord-015369-72cjogxz 1887 10 % % NN cord-015369-72cjogxz 1887 11 ) ) -RRB- cord-015369-72cjogxz 1887 12 with with IN cord-015369-72cjogxz 1887 13 ileus ileus NNP cord-015369-72cjogxz 1887 14 . . . cord-015369-72cjogxz 1888 1 All all DT cord-015369-72cjogxz 1888 2 patients patient NNS cord-015369-72cjogxz 1888 3 received receive VBD cord-015369-72cjogxz 1888 4 a a DT cord-015369-72cjogxz 1888 5 resection resection NN cord-015369-72cjogxz 1888 6 ( ( -LRB- cord-015369-72cjogxz 1888 7 colon colon NN cord-015369-72cjogxz 1888 8 50/ 50/ CD cord-015369-72cjogxz 1888 9 64 64 CD cord-015369-72cjogxz 1888 10 , , , cord-015369-72cjogxz 1888 11 rectum rectum NN cord-015369-72cjogxz 1888 12 14/64 14/64 CD cord-015369-72cjogxz 1888 13 ) ) -RRB- cord-015369-72cjogxz 1888 14 by by IN cord-015369-72cjogxz 1888 15 laparatomy laparatomy NNP cord-015369-72cjogxz 1888 16 with with IN cord-015369-72cjogxz 1888 17 primary primary JJ cord-015369-72cjogxz 1888 18 anastomosis anastomosis NN cord-015369-72cjogxz 1888 19 in in IN cord-015369-72cjogxz 1888 20 44 44 CD cord-015369-72cjogxz 1888 21 ( ( -LRB- cord-015369-72cjogxz 1888 22 68.8 68.8 CD cord-015369-72cjogxz 1888 23 % % NN cord-015369-72cjogxz 1888 24 ) ) -RRB- cord-015369-72cjogxz 1888 25 patients patient NNS cord-015369-72cjogxz 1888 26 . . . cord-015369-72cjogxz 1889 1 The the DT cord-015369-72cjogxz 1889 2 median median JJ cord-015369-72cjogxz 1889 3 age age NN cord-015369-72cjogxz 1889 4 was be VBD cord-015369-72cjogxz 1889 5 73 73 CD cord-015369-72cjogxz 1889 6 y y NN cord-015369-72cjogxz 1889 7 ( ( -LRB- cord-015369-72cjogxz 1889 8 28 28 CD cord-015369-72cjogxz 1889 9 - - SYM cord-015369-72cjogxz 1889 10 93 93 CD cord-015369-72cjogxz 1889 11 ) ) -RRB- cord-015369-72cjogxz 1889 12 . . . cord-015369-72cjogxz 1890 1 The the DT cord-015369-72cjogxz 1890 2 level level NN cord-015369-72cjogxz 1890 3 of of IN cord-015369-72cjogxz 1890 4 chronic chronic JJ cord-015369-72cjogxz 1890 5 comorbidity comorbidity NN cord-015369-72cjogxz 1890 6 was be VBD cord-015369-72cjogxz 1890 7 high high JJ cord-015369-72cjogxz 1890 8 : : : cord-015369-72cjogxz 1890 9 ! ! . cord-015369-72cjogxz 1891 1 ASA ASA NNP cord-015369-72cjogxz 1891 2 III III NNP cord-015369-72cjogxz 1891 3 55/64 55/64 CD cord-015369-72cjogxz 1891 4 ( ( -LRB- cord-015369-72cjogxz 1891 5 85.9 85.9 CD cord-015369-72cjogxz 1891 6 % % NN cord-015369-72cjogxz 1891 7 ) ) -RRB- cord-015369-72cjogxz 1891 8 . . . cord-015369-72cjogxz 1892 1 Results result NNS cord-015369-72cjogxz 1892 2 . . . cord-015369-72cjogxz 1893 1 The the DT cord-015369-72cjogxz 1893 2 essential essential JJ cord-015369-72cjogxz 1893 3 modules module NNS cord-015369-72cjogxz 1893 4 of of IN cord-015369-72cjogxz 1893 5 FTR FTR NNP cord-015369-72cjogxz 1893 6 could could MD cord-015369-72cjogxz 1893 7 be be VB cord-015369-72cjogxz 1893 8 applied apply VBN cord-015369-72cjogxz 1893 9 successfully successfully RB cord-015369-72cjogxz 1893 10 intra intra JJ cord-015369-72cjogxz 1893 11 - - : cord-015369-72cjogxz 1893 12 and and CC cord-015369-72cjogxz 1893 13 postoperatively postoperatively RB cord-015369-72cjogxz 1893 14 : : : cord-015369-72cjogxz 1894 1 -Thoracic -Thoracic . cord-015369-72cjogxz 1895 1 epidural epidural NNP cord-015369-72cjogxz 1895 2 catheter catheter NN cord-015369-72cjogxz 1895 3 : : : cord-015369-72cjogxz 1895 4 39 39 CD cord-015369-72cjogxz 1895 5 ( ( -LRB- cord-015369-72cjogxz 1895 6 60.9 60.9 CD cord-015369-72cjogxz 1895 7 % % NN cord-015369-72cjogxz 1895 8 ) ) -RRB- cord-015369-72cjogxz 1896 1 -Nasogastric -nasogastric JJ cord-015369-72cjogxz 1896 2 tube tube NN cord-015369-72cjogxz 1896 3 removed remove VBN cord-015369-72cjogxz 1896 4 at at IN cord-015369-72cjogxz 1896 5 the the DT cord-015369-72cjogxz 1896 6 end end NN cord-015369-72cjogxz 1896 7 of of IN cord-015369-72cjogxz 1896 8 operation operation NN cord-015369-72cjogxz 1896 9 : : : cord-015369-72cjogxz 1896 10 46 46 CD cord-015369-72cjogxz 1896 11 ( ( -LRB- cord-015369-72cjogxz 1896 12 74.2 74.2 CD cord-015369-72cjogxz 1896 13 % % NN cord-015369-72cjogxz 1896 14 ) ) -RRB- cord-015369-72cjogxz 1897 1 -Necessity -necessity NN cord-015369-72cjogxz 1897 2 of of IN cord-015369-72cjogxz 1897 3 replacement replacement NN cord-015369-72cjogxz 1897 4 of of IN cord-015369-72cjogxz 1897 5 nasogastric nasogastric NN cord-015369-72cjogxz 1897 6 tube tube NN cord-015369-72cjogxz 1897 7 : : : cord-015369-72cjogxz 1897 8 7 7 CD cord-015369-72cjogxz 1897 9 ( ( -LRB- cord-015369-72cjogxz 1897 10 10.9 10.9 CD cord-015369-72cjogxz 1897 11 % % NN cord-015369-72cjogxz 1897 12 ) ) -RRB- cord-015369-72cjogxz 1897 13 -Bowel -bowel IN cord-015369-72cjogxz 1897 14 stimulation stimulation NN cord-015369-72cjogxz 1897 15 : : : cord-015369-72cjogxz 1897 16 14 14 CD cord-015369-72cjogxz 1897 17 ( ( -LRB- cord-015369-72cjogxz 1897 18 21.3 21.3 CD cord-015369-72cjogxz 1897 19 % % NN cord-015369-72cjogxz 1897 20 ) ) -RRB- cord-015369-72cjogxz 1898 1 -Normal -normal JJ cord-015369-72cjogxz 1898 2 food food NN cord-015369-72cjogxz 1898 3 intake intake NN cord-015369-72cjogxz 1898 4 at at IN cord-015369-72cjogxz 1898 5 1st 1st JJ cord-015369-72cjogxz 1898 6 day day NN cord-015369-72cjogxz 1898 7 : : : cord-015369-72cjogxz 1898 8 45 45 CD cord-015369-72cjogxz 1898 9 ( ( -LRB- cord-015369-72cjogxz 1898 10 70.3 70.3 CD cord-015369-72cjogxz 1898 11 % % NN cord-015369-72cjogxz 1898 12 ) ) -RRB- cord-015369-72cjogxz 1899 1 -Normal -normal JJ cord-015369-72cjogxz 1899 2 bowel bowel JJ cord-015369-72cjogxz 1899 3 movement movement NN cord-015369-72cjogxz 1899 4 at at IN cord-015369-72cjogxz 1899 5 postoperative postoperative JJ cord-015369-72cjogxz 1899 6 day day NN cord-015369-72cjogxz 1899 7 ( ( -LRB- cord-015369-72cjogxz 1899 8 m m NNP cord-015369-72cjogxz 1899 9 ) ) -RRB- cord-015369-72cjogxz 1899 10 : : : cord-015369-72cjogxz 1899 11 2 2 LS cord-015369-72cjogxz 1899 12 ( ( -LRB- cord-015369-72cjogxz 1899 13 1 1 CD cord-015369-72cjogxz 1899 14 - - SYM cord-015369-72cjogxz 1899 15 7 7 CD cord-015369-72cjogxz 1899 16 ) ) -RRB- cord-015369-72cjogxz 1899 17 -Days -day NNS cord-015369-72cjogxz 1899 18 of of IN cord-015369-72cjogxz 1899 19 stay stay NN cord-015369-72cjogxz 1899 20 in in IN cord-015369-72cjogxz 1899 21 the the DT cord-015369-72cjogxz 1899 22 ICU ICU NNP cord-015369-72cjogxz 1899 23 ( ( -LRB- cord-015369-72cjogxz 1899 24 m m NN cord-015369-72cjogxz 1899 25 ) ) -RRB- cord-015369-72cjogxz 1899 26 : : : cord-015369-72cjogxz 1899 27 2 2 LS cord-015369-72cjogxz 1899 28 ( ( -LRB- cord-015369-72cjogxz 1899 29 1 1 CD cord-015369-72cjogxz 1899 30 - - SYM cord-015369-72cjogxz 1899 31 11 11 CD cord-015369-72cjogxz 1899 32 ) ) -RRB- cord-015369-72cjogxz 1900 1 The the DT cord-015369-72cjogxz 1900 2 rates rate NNS cord-015369-72cjogxz 1900 3 of of IN cord-015369-72cjogxz 1900 4 major major JJ cord-015369-72cjogxz 1900 5 complications complication NNS cord-015369-72cjogxz 1900 6 were be VBD cord-015369-72cjogxz 1900 7 : : : cord-015369-72cjogxz 1900 8 -Insufficiency -insufficiency DT cord-015369-72cjogxz 1900 9 of of IN cord-015369-72cjogxz 1900 10 anastomosis anastomosis NN cord-015369-72cjogxz 1900 11 : : : cord-015369-72cjogxz 1900 12 1 1 CD cord-015369-72cjogxz 1900 13 ( ( -LRB- cord-015369-72cjogxz 1900 14 2.3 2.3 CD cord-015369-72cjogxz 1900 15 % % NN cord-015369-72cjogxz 1900 16 ) ) -RRB- cord-015369-72cjogxz 1901 1 -Wound -wound DT cord-015369-72cjogxz 1901 2 infection infection NN cord-015369-72cjogxz 1901 3 : : : cord-015369-72cjogxz 1901 4 5 5 CD cord-015369-72cjogxz 1901 5 ( ( -LRB- cord-015369-72cjogxz 1901 6 7.8 7.8 CD cord-015369-72cjogxz 1901 7 % % NN cord-015369-72cjogxz 1901 8 ) ) -RRB- cord-015369-72cjogxz 1902 1 -Pneumonia -Pneumonia NNP cord-015369-72cjogxz 1902 2 : : : cord-015369-72cjogxz 1902 3 5 5 LS cord-015369-72cjogxz 1902 4 ( ( -LRB- cord-015369-72cjogxz 1902 5 7.8 7.8 CD cord-015369-72cjogxz 1902 6 % % NN cord-015369-72cjogxz 1902 7 ) ) -RRB- cord-015369-72cjogxz 1903 1 -Overall -overall RB cord-015369-72cjogxz 1903 2 mortality mortality NN cord-015369-72cjogxz 1903 3 : : : cord-015369-72cjogxz 1903 4 11 11 CD cord-015369-72cjogxz 1903 5 ( ( -LRB- cord-015369-72cjogxz 1903 6 17.2 17.2 CD cord-015369-72cjogxz 1903 7 % % NN cord-015369-72cjogxz 1903 8 ) ) -RRB- cord-015369-72cjogxz 1903 9 Conclusions conclusion NNS cord-015369-72cjogxz 1903 10 . . . cord-015369-72cjogxz 1904 1 -The -The : cord-015369-72cjogxz 1904 2 high high JJ cord-015369-72cjogxz 1904 3 mortality mortality NN cord-015369-72cjogxz 1904 4 was be VBD cord-015369-72cjogxz 1904 5 due due JJ cord-015369-72cjogxz 1904 6 to to IN cord-015369-72cjogxz 1904 7 the the DT cord-015369-72cjogxz 1904 8 elderly elderly JJ cord-015369-72cjogxz 1904 9 population population NN cord-015369-72cjogxz 1904 10 and and CC cord-015369-72cjogxz 1904 11 concomitant concomitant JJ cord-015369-72cjogxz 1904 12 diseases disease NNS cord-015369-72cjogxz 1904 13 . . . cord-015369-72cjogxz 1905 1 -No -No : cord-015369-72cjogxz 1905 2 deaths death NNS cord-015369-72cjogxz 1905 3 were be VBD cord-015369-72cjogxz 1905 4 seen see VBN cord-015369-72cjogxz 1905 5 from from IN cord-015369-72cjogxz 1905 6 surgical surgical JJ cord-015369-72cjogxz 1905 7 complications complication NNS cord-015369-72cjogxz 1905 8 . . . cord-015369-72cjogxz 1906 1 -Based -base VBN cord-015369-72cjogxz 1906 2 on on IN cord-015369-72cjogxz 1906 3 good good JJ cord-015369-72cjogxz 1906 4 acceptance acceptance NN cord-015369-72cjogxz 1906 5 , , , cord-015369-72cjogxz 1906 6 low low JJ cord-015369-72cjogxz 1906 7 rates rate NNS cord-015369-72cjogxz 1906 8 of of IN cord-015369-72cjogxz 1906 9 major major JJ cord-015369-72cjogxz 1906 10 complications complication NNS cord-015369-72cjogxz 1906 11 and and CC cord-015369-72cjogxz 1906 12 excellent excellent JJ cord-015369-72cjogxz 1906 13 results result NNS cord-015369-72cjogxz 1906 14 in in IN cord-015369-72cjogxz 1906 15 GI GI NNP cord-015369-72cjogxz 1906 16 recovery recovery NN cord-015369-72cjogxz 1906 17 FTR FTR NNP cord-015369-72cjogxz 1906 18 is be VBZ cord-015369-72cjogxz 1906 19 suitable suitable JJ cord-015369-72cjogxz 1906 20 for for IN cord-015369-72cjogxz 1906 21 emergency emergency NN cord-015369-72cjogxz 1906 22 colorectal colorectal JJ cord-015369-72cjogxz 1906 23 surgery surgery NN cord-015369-72cjogxz 1906 24 and and CC cord-015369-72cjogxz 1906 25 can can MD cord-015369-72cjogxz 1906 26 be be VB cord-015369-72cjogxz 1906 27 recommended recommend VBN cord-015369-72cjogxz 1906 28 for for IN cord-015369-72cjogxz 1906 29 therapy therapy NN cord-015369-72cjogxz 1906 30 of of IN cord-015369-72cjogxz 1906 31 acute acute JJ cord-015369-72cjogxz 1906 32 ileus ileus NNP cord-015369-72cjogxz 1906 33 . . . cord-015369-72cjogxz 1907 1 Mit Mit NNP cord-015369-72cjogxz 1907 2 der der NNP cord-015369-72cjogxz 1907 3 ACCENT ACCENT NNP cord-015369-72cjogxz 1907 4 II II NNP cord-015369-72cjogxz 1907 5 Studie Studie NNP cord-015369-72cjogxz 1907 6 hat hat NN cord-015369-72cjogxz 1907 7 die die VBP cord-015369-72cjogxz 1908 1 Anti Anti NNP cord-015369-72cjogxz 1908 2 - - JJ cord-015369-72cjogxz 1908 3 TNF tnf NN cord-015369-72cjogxz 1908 4 - - HYPH cord-015369-72cjogxz 1908 5 alpha alpha NN cord-015369-72cjogxz 1908 6 - - HYPH cord-015369-72cjogxz 1908 7 Therapie Therapie NNP cord-015369-72cjogxz 1908 8 einen einen NNP cord-015369-72cjogxz 1908 9 zentralen zentralen NNP cord-015369-72cjogxz 1908 10 Stellenwert Stellenwert NNP cord-015369-72cjogxz 1908 11 insbesonders insbesonders NN cord-015369-72cjogxz 1908 12 beim beim NNP cord-015369-72cjogxz 1908 13 fistulierenden fistulierenden VBD cord-015369-72cjogxz 1908 14 M. M. NNP cord-015369-72cjogxz 1908 15 Crohn Crohn NNP cord-015369-72cjogxz 1908 16 etabliert etabliert NN cord-015369-72cjogxz 1908 17 [ [ -LRB- cord-015369-72cjogxz 1908 18 1 1 CD cord-015369-72cjogxz 1908 19 ] ] -RRB- cord-015369-72cjogxz 1908 20 . . . cord-015369-72cjogxz 1909 1 In in IN cord-015369-72cjogxz 1909 2 weiterer weiterer JJ cord-015369-72cjogxz 1909 3 Folge Folge NNP cord-015369-72cjogxz 1909 4 stellte stellte NNP cord-015369-72cjogxz 1909 5 sich sich NNP cord-015369-72cjogxz 1909 6 die die VBP cord-015369-72cjogxz 1909 7 Frage Frage NNP cord-015369-72cjogxz 1909 8 , , , cord-015369-72cjogxz 1909 9 inwieweit inwieweit NNP cord-015369-72cjogxz 1909 10 die die NNP cord-015369-72cjogxz 1909 11 notwendige notwendige NNP cord-015369-72cjogxz 1909 12 operative operative JJ cord-015369-72cjogxz 1910 1 Therapie Therapie NNP cord-015369-72cjogxz 1910 2 des des FW cord-015369-72cjogxz 1910 3 fistulierenden fistulierenden VBD cord-015369-72cjogxz 1910 4 anorektalen anorektalen NNP cord-015369-72cjogxz 1910 5 M. M. NNP cord-015369-72cjogxz 1910 6 Crohn Crohn NNP cord-015369-72cjogxz 1910 7 durch durch NNP cord-015369-72cjogxz 1910 8 die die VBP cord-015369-72cjogxz 1911 1 Anti Anti NNP cord-015369-72cjogxz 1911 2 - - JJ cord-015369-72cjogxz 1911 3 TNF tnf NN cord-015369-72cjogxz 1911 4 - - HYPH cord-015369-72cjogxz 1911 5 alpha alpha NN cord-015369-72cjogxz 1911 6 - - HYPH cord-015369-72cjogxz 1911 7 Anwendung Anwendung NNP cord-015369-72cjogxz 1911 8 positiv positiv JJ cord-015369-72cjogxz 1911 9 oder oder NNP cord-015369-72cjogxz 1911 10 negativ negativ NNP cord-015369-72cjogxz 1911 11 beeinflusst beeinflusst NNP cord-015369-72cjogxz 1911 12 werden werden NNP cord-015369-72cjogxz 1911 13 könnte könnte NNP cord-015369-72cjogxz 1911 14 [ [ -LRB- cord-015369-72cjogxz 1911 15 2 2 CD cord-015369-72cjogxz 1911 16 , , , cord-015369-72cjogxz 1911 17 3 3 CD cord-015369-72cjogxz 1911 18 ] ] -RRB- cord-015369-72cjogxz 1911 19 . . . cord-015369-72cjogxz 1912 1 Als Als NNP cord-015369-72cjogxz 1912 2 weiteren weiteren NNP cord-015369-72cjogxz 1913 1 Schritt Schritt NNP cord-015369-72cjogxz 1913 2 sehen sehen NNP cord-015369-72cjogxz 1914 1 wir wir NNP cord-015369-72cjogxz 1914 2 die die VBP cord-015369-72cjogxz 1914 3 Anwendung Anwendung NNP cord-015369-72cjogxz 1914 4 dieser dieser NNP cord-015369-72cjogxz 1914 5 Therapie Therapie NNP cord-015369-72cjogxz 1914 6 mit mit NNP cord-015369-72cjogxz 1914 7 Infliximab Infliximab NNP cord-015369-72cjogxz 1914 8 , , , cord-015369-72cjogxz 1914 9 beim beim NNP cord-015369-72cjogxz 1914 10 schweren schweren NNP cord-015369-72cjogxz 1914 11 anorektalen anorektalen NNP cord-015369-72cjogxz 1914 12 M. M. NNP cord-015369-72cjogxz 1914 13 Crohn Crohn NNP cord-015369-72cjogxz 1914 14 , , , cord-015369-72cjogxz 1914 15 um um UH cord-015369-72cjogxz 1914 16 Voraussetzungen Voraussetzungen NNP cord-015369-72cjogxz 1914 17 zu zu NNP cord-015369-72cjogxz 1914 18 schaffen schaffen NNP cord-015369-72cjogxz 1914 19 , , , cord-015369-72cjogxz 1915 1 den den NNP cord-015369-72cjogxz 1915 2 operativen operativen NNP cord-015369-72cjogxz 1915 3 Eingriff Eingriff NNP cord-015369-72cjogxz 1915 4 zu zu NNP cord-015369-72cjogxz 1915 5 minimieren minimieren NNP cord-015369-72cjogxz 1915 6 oder oder NNP cord-015369-72cjogxz 1915 7 weiterreichende weiterreichende NNP cord-015369-72cjogxz 1916 1 auch auch NNP cord-015369-72cjogxz 1916 2 rekonstruktive rekonstruktive NNP cord-015369-72cjogxz 1916 3 Eingriffe Eingriffe NNP cord-015369-72cjogxz 1916 4 in in IN cord-015369-72cjogxz 1916 5 dieser dieser NNP cord-015369-72cjogxz 1916 6 Region Region NNP cord-015369-72cjogxz 1916 7 zu zu NNP cord-015369-72cjogxz 1916 8 ermöglichen ermöglichen NNP cord-015369-72cjogxz 1916 9 . . . cord-015369-72cjogxz 1917 1 Unsere Unsere NNP cord-015369-72cjogxz 1917 2 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 1917 3 beziehen beziehen NNP cord-015369-72cjogxz 1917 4 sich sich NNP cord-015369-72cjogxz 1917 5 auf auf NNP cord-015369-72cjogxz 1917 6 insgesamt insgesamt NNP cord-015369-72cjogxz 1917 7 80 80 CD cord-015369-72cjogxz 1917 8 Patienten Patienten NNP cord-015369-72cjogxz 1917 9 mit mit NNP cord-015369-72cjogxz 1917 10 schwerem schwerem NN cord-015369-72cjogxz 1917 11 anorektalem anorektalem NNP cord-015369-72cjogxz 1917 12 M. M. NNP cord-015369-72cjogxz 1917 13 Crohn Crohn NNP cord-015369-72cjogxz 1917 14 , , , cord-015369-72cjogxz 1917 15 von von NNP cord-015369-72cjogxz 1917 16 denen denen NNP cord-015369-72cjogxz 1917 17 14 14 CD cord-015369-72cjogxz 1917 18 einer einer NNP cord-015369-72cjogxz 1918 1 Anti Anti NNP cord-015369-72cjogxz 1918 2 - - JJ cord-015369-72cjogxz 1918 3 TNF tnf NN cord-015369-72cjogxz 1918 4 - - HYPH cord-015369-72cjogxz 1918 5 alpha alpha NN cord-015369-72cjogxz 1918 6 - - HYPH cord-015369-72cjogxz 1918 7 Therapie Therapie NNP cord-015369-72cjogxz 1918 8 zugeführt zugeführt NN cord-015369-72cjogxz 1918 9 wurden wurden NNP cord-015369-72cjogxz 1918 10 . . . cord-015369-72cjogxz 1919 1 Insgesamt Insgesamt NNP cord-015369-72cjogxz 1919 2 wurden wurden VBD cord-015369-72cjogxz 1919 3 an an DT cord-015369-72cjogxz 1919 4 diesen diesen NNP cord-015369-72cjogxz 1919 5 Patienten Patienten NNP cord-015369-72cjogxz 1919 6 22 22 CD cord-015369-72cjogxz 1919 7 Abszessdrainagen Abszessdrainagen NNP cord-015369-72cjogxz 1919 8 , , , cord-015369-72cjogxz 1919 9 23 23 CD cord-015369-72cjogxz 1919 10 Fistelspaltungen Fistelspaltungen NNP cord-015369-72cjogxz 1919 11 , , , cord-015369-72cjogxz 1920 1 15 15 CD cord-015369-72cjogxz 1920 2 Fistelexzisionen Fistelexzisionen NNP cord-015369-72cjogxz 1920 3 , , , cord-015369-72cjogxz 1920 4 sowie sowie JJ cord-015369-72cjogxz 1920 5 10 10 CD cord-015369-72cjogxz 1920 6 Exzisionen Exzisionen NNP cord-015369-72cjogxz 1920 7 mit mit NNP cord-015369-72cjogxz 1920 8 Mucosa Mucosa NNP cord-015369-72cjogxz 1920 9 - - HYPH cord-015369-72cjogxz 1920 10 Flap Flap NNP cord-015369-72cjogxz 1920 11 durchgeführt durchgeführt NN cord-015369-72cjogxz 1920 12 . . . cord-015369-72cjogxz 1921 1 Bei Bei NNP cord-015369-72cjogxz 1921 2 13 13 CD cord-015369-72cjogxz 1921 3 Patienten Patienten NNP cord-015369-72cjogxz 1921 4 musste musste NNP cord-015369-72cjogxz 1922 1 wegen wegen NNP cord-015369-72cjogxz 1922 2 schwerer schwerer NNP cord-015369-72cjogxz 1922 3 Abszedierung Abszedierung NNP cord-015369-72cjogxz 1922 4 oder oder NNP cord-015369-72cjogxz 1922 5 Destruktion Destruktion NNP cord-015369-72cjogxz 1923 1 eine eine NNP cord-015369-72cjogxz 1923 2 Hartmann Hartmann NNP cord-015369-72cjogxz 1923 3 - - HYPH cord-015369-72cjogxz 1923 4 Deviation Deviation NNP cord-015369-72cjogxz 1923 5 angelegt angelegt RB cord-015369-72cjogxz 1924 1 werden werden NNP cord-015369-72cjogxz 1924 2 . . . cord-015369-72cjogxz 1925 1 6 6 CD cord-015369-72cjogxz 1926 1 Patienten Patienten NNP cord-015369-72cjogxz 1926 2 konnten konnten NNP cord-015369-72cjogxz 1926 3 einer einer NNP cord-015369-72cjogxz 1926 4 intestinalen intestinalen NNP cord-015369-72cjogxz 1926 5 Rekonstruktion Rekonstruktion NNP cord-015369-72cjogxz 1926 6 , , , cord-015369-72cjogxz 1926 7 5 5 CD cord-015369-72cjogxz 1926 8 Patienten Patienten NNP cord-015369-72cjogxz 1926 9 einer einer NNP cord-015369-72cjogxz 1926 10 Sphinkterrekonstruktion Sphinkterrekonstruktion NNP cord-015369-72cjogxz 1926 11 zugeführt zugeführt NNP cord-015369-72cjogxz 1926 12 werden werden NNP cord-015369-72cjogxz 1926 13 . . . cord-015369-72cjogxz 1927 1 Bei Bei NNP cord-015369-72cjogxz 1927 2 7 7 CD cord-015369-72cjogxz 1927 3 Patienten Patienten NNP cord-015369-72cjogxz 1927 4 konnte konnte NNP cord-015369-72cjogxz 1927 5 , , , cord-015369-72cjogxz 1927 6 bei bei NNP cord-015369-72cjogxz 1927 7 bestehender bestehender NNP cord-015369-72cjogxz 1927 8 Fistel Fistel NNP cord-015369-72cjogxz 1927 9 , , , cord-015369-72cjogxz 1927 10 eine eine NNP cord-015369-72cjogxz 1927 11 größere größere NNP cord-015369-72cjogxz 1927 12 Operation Operation NNP cord-015369-72cjogxz 1927 13 , , , cord-015369-72cjogxz 1927 14 durch durch NNP cord-015369-72cjogxz 1927 15 Minimierung Minimierung NNP cord-015369-72cjogxz 1927 16 der der NN cord-015369-72cjogxz 1927 17 symptomatischen symptomatischen NNP cord-015369-72cjogxz 1927 18 Belastung Belastung NNP cord-015369-72cjogxz 1927 19 der der NNP cord-015369-72cjogxz 1927 20 Lebensqualität Lebensqualität NNP cord-015369-72cjogxz 1927 21 , , , cord-015369-72cjogxz 1927 22 vermieden vermieden NNP cord-015369-72cjogxz 1927 23 werden werden NNP cord-015369-72cjogxz 1927 24 . . . cord-015369-72cjogxz 1928 1 Wir Wir NNP cord-015369-72cjogxz 1928 2 sehen sehen NNP cord-015369-72cjogxz 1928 3 heute heute NNP cord-015369-72cjogxz 1928 4 die die NNP cord-015369-72cjogxz 1929 1 Anti Anti NNP cord-015369-72cjogxz 1929 2 - - NNP cord-015369-72cjogxz 1929 3 TNF tnf NN cord-015369-72cjogxz 1929 4 - - HYPH cord-015369-72cjogxz 1929 5 alpha alpha NN cord-015369-72cjogxz 1929 6 Therapie Therapie NNP cord-015369-72cjogxz 1929 7 als als NNP cord-015369-72cjogxz 1929 8 zusätzliche zusätzliche NNP cord-015369-72cjogxz 1929 9 Option Option NNP cord-015369-72cjogxz 1929 10 einerseits einerseit NNS cord-015369-72cjogxz 1929 11 weiterreichende weiterreichende NNP cord-015369-72cjogxz 1929 12 operative operative NN cord-015369-72cjogxz 1929 13 Eingriffe Eingriffe NNP cord-015369-72cjogxz 1929 14 zu zu NNP cord-015369-72cjogxz 1929 15 vermeiden vermeiden NNP cord-015369-72cjogxz 1930 1 , , , cord-015369-72cjogxz 1930 2 oder oder NNP cord-015369-72cjogxz 1930 3 aber aber NNP cord-015369-72cjogxz 1930 4 andererseits andererseits NNP cord-015369-72cjogxz 1930 5 rekonstruktiv rekonstruktiv NNP cord-015369-72cjogxz 1931 1 zu zu NNP cord-015369-72cjogxz 1931 2 ermöglichen ermöglichen NNP cord-015369-72cjogxz 1931 3 . . . cord-015369-72cjogxz 1932 1 Methodik Methodik NNP cord-015369-72cjogxz 1932 2 . . . cord-015369-72cjogxz 1933 1 Unter Unter NNP cord-015369-72cjogxz 1933 2 56 56 CD cord-015369-72cjogxz 1934 1 laparoskopisch laparoskopisch JJ cord-015369-72cjogxz 1934 2 - - HYPH cord-015369-72cjogxz 1934 3 assistiert assistiert NNP cord-015369-72cjogxz 1934 4 operierten operierten NNP cord-015369-72cjogxz 1935 1 Patienten Patienten NNP cord-015369-72cjogxz 1935 2 waren waren VBD cord-015369-72cjogxz 1935 3 28 28 CD cord-015369-72cjogxz 1935 4 ( ( -LRB- cord-015369-72cjogxz 1935 5 10 10 CD cord-015369-72cjogxz 1935 6 weiblich weiblich NNP cord-015369-72cjogxz 1935 7 ) ) -RRB- cord-015369-72cjogxz 1935 8 , , . cord-015369-72cjogxz 1936 1 die die VB cord-015369-72cjogxz 1936 2 entweder entweder NNP cord-015369-72cjogxz 1936 3 ein ein NNP cord-015369-72cjogxz 1936 4 Crohnrezidiv Crohnrezidiv NNP cord-015369-72cjogxz 1936 5 ( ( -LRB- cord-015369-72cjogxz 1936 6 13 13 CD cord-015369-72cjogxz 1936 7 ) ) -RRB- cord-015369-72cjogxz 1937 1 nach nach NNP cord-015369-72cjogxz 1937 2 offener offener NNP cord-015369-72cjogxz 1938 1 oder oder NNP cord-015369-72cjogxz 1938 2 laparoskopischer laparoskopischer NNP cord-015369-72cjogxz 1938 3 Voroperation Voroperation NNP cord-015369-72cjogxz 1938 4 oder oder NNP cord-015369-72cjogxz 1938 5 Komplikationen Komplikationen NNP cord-015369-72cjogxz 1939 1 durch durch NNP cord-015369-72cjogxz 1939 2 vorbestehende vorbestehende NNP cord-015369-72cjogxz 1939 3 entero entero NNP cord-015369-72cjogxz 1939 4 - - HYPH cord-015369-72cjogxz 1939 5 enterale enterale NNP cord-015369-72cjogxz 1939 6 , , , cord-015369-72cjogxz 1939 7 entero entero NNP cord-015369-72cjogxz 1939 8 - - HYPH cord-015369-72cjogxz 1939 9 vesicale vesicale NNP cord-015369-72cjogxz 1939 10 oder oder NNP cord-015369-72cjogxz 1939 11 entero entero NNP cord-015369-72cjogxz 1939 12 - - HYPH cord-015369-72cjogxz 1939 13 vaginale vaginale NNP cord-015369-72cjogxz 1939 14 Fisteln Fisteln NNP cord-015369-72cjogxz 1939 15 ( ( -LRB- cord-015369-72cjogxz 1939 16 6 6 CD cord-015369-72cjogxz 1939 17 ) ) -RRB- cord-015369-72cjogxz 1939 18 , , , cord-015369-72cjogxz 1939 19 Abszesse Abszesse NNP cord-015369-72cjogxz 1939 20 ( ( -LRB- cord-015369-72cjogxz 1939 21 7 7 CD cord-015369-72cjogxz 1939 22 ) ) -RRB- cord-015369-72cjogxz 1939 23 , , , cord-015369-72cjogxz 1939 24 gedeckte gedeckte NNP cord-015369-72cjogxz 1939 25 Perforation Perforation NNP cord-015369-72cjogxz 1939 26 ( ( -LRB- cord-015369-72cjogxz 1939 27 8) 8) NNP cord-015369-72cjogxz 1939 28 oder oder NNP cord-015369-72cjogxz 1939 29 entzündliche entzündliche NNP cord-015369-72cjogxz 1939 30 Konglomerattumoren Konglomerattumoren NNP cord-015369-72cjogxz 1939 31 ( ( -LRB- cord-015369-72cjogxz 1939 32 6 6 CD cord-015369-72cjogxz 1939 33 ) ) -RRB- cord-015369-72cjogxz 1939 34 Background background NN cord-015369-72cjogxz 1939 35 . . . cord-015369-72cjogxz 1940 1 Hyperthermic Hyperthermic NNP cord-015369-72cjogxz 1940 2 intraperitoneal intraperitoneal JJ cord-015369-72cjogxz 1940 3 chemotherapy chemotherapy NN cord-015369-72cjogxz 1940 4 ( ( -LRB- cord-015369-72cjogxz 1940 5 HIPEC HIPEC NNP cord-015369-72cjogxz 1940 6 ) ) -RRB- cord-015369-72cjogxz 1940 7 combined combine VBN cord-015369-72cjogxz 1940 8 with with IN cord-015369-72cjogxz 1940 9 cytoreductive cytoreductive JJ cord-015369-72cjogxz 1940 10 surgery surgery NN cord-015369-72cjogxz 1940 11 ( ( -LRB- cord-015369-72cjogxz 1940 12 CRS CRS NNP cord-015369-72cjogxz 1940 13 ) ) -RRB- cord-015369-72cjogxz 1940 14 is be VBZ cord-015369-72cjogxz 1940 15 an an DT cord-015369-72cjogxz 1940 16 important important JJ cord-015369-72cjogxz 1940 17 treatment treatment NN cord-015369-72cjogxz 1940 18 option option NN cord-015369-72cjogxz 1940 19 for for IN cord-015369-72cjogxz 1940 20 patients patient NNS cord-015369-72cjogxz 1940 21 with with IN cord-015369-72cjogxz 1940 22 peritoneal peritoneal JJ cord-015369-72cjogxz 1940 23 surface surface NN cord-015369-72cjogxz 1940 24 malignancies malignancy NNS cord-015369-72cjogxz 1940 25 . . . cord-015369-72cjogxz 1941 1 For for IN cord-015369-72cjogxz 1941 2 close close JJ cord-015369-72cjogxz 1941 3 to to TO cord-015369-72cjogxz 1941 4 ten ten CD cord-015369-72cjogxz 1941 5 years year NNS cord-015369-72cjogxz 1941 6 the the DT cord-015369-72cjogxz 1941 7 Kantonsspital Kantonsspital NNP cord-015369-72cjogxz 1941 8 St. St. NNP cord-015369-72cjogxz 1941 9 Gallen Gallen NNP cord-015369-72cjogxz 1941 10 has have VBZ cord-015369-72cjogxz 1941 11 been be VBN cord-015369-72cjogxz 1941 12 offering offer VBG cord-015369-72cjogxz 1941 13 this this DT cord-015369-72cjogxz 1941 14 therapy therapy NN cord-015369-72cjogxz 1941 15 . . . cord-015369-72cjogxz 1942 1 Methods method NNS cord-015369-72cjogxz 1942 2 . . . cord-015369-72cjogxz 1943 1 Since since IN cord-015369-72cjogxz 1943 2 2000 2000 CD cord-015369-72cjogxz 1943 3 , , , cord-015369-72cjogxz 1943 4 80 80 CD cord-015369-72cjogxz 1943 5 patients patient NNS cord-015369-72cjogxz 1943 6 with with IN cord-015369-72cjogxz 1943 7 peritoneal peritoneal JJ cord-015369-72cjogxz 1943 8 surface surface NN cord-015369-72cjogxz 1943 9 malignancies malignancy NNS cord-015369-72cjogxz 1943 10 were be VBD cord-015369-72cjogxz 1943 11 treated treat VBN cord-015369-72cjogxz 1943 12 with with IN cord-015369-72cjogxz 1943 13 CRS CRS NNP cord-015369-72cjogxz 1943 14 and and CC cord-015369-72cjogxz 1943 15 HIPEC HIPEC NNP cord-015369-72cjogxz 1943 16 as as IN cord-015369-72cjogxz 1943 17 described describe VBN cord-015369-72cjogxz 1943 18 by by IN cord-015369-72cjogxz 1943 19 Sugarbaker Sugarbaker NNP cord-015369-72cjogxz 1943 20 . . . cord-015369-72cjogxz 1944 1 HIPEC HIPEC NNP cord-015369-72cjogxz 1944 2 was be VBD cord-015369-72cjogxz 1944 3 performed perform VBN cord-015369-72cjogxz 1944 4 using use VBG cord-015369-72cjogxz 1944 5 the the DT cord-015369-72cjogxz 1944 6 open open JJ cord-015369-72cjogxz 1944 7 coliseum coliseum NNP cord-015369-72cjogxz 1944 8 technique technique NN cord-015369-72cjogxz 1944 9 with with IN cord-015369-72cjogxz 1944 10 mitomycin mitomycin NNS cord-015369-72cjogxz 1944 11 ( ( -LRB- cord-015369-72cjogxz 1944 12 25 25 CD cord-015369-72cjogxz 1944 13 mg mg NNP cord-015369-72cjogxz 1944 14 / / SYM cord-015369-72cjogxz 1944 15 m m NNP cord-015369-72cjogxz 1944 16 2 2 CD cord-015369-72cjogxz 1944 17 ) ) -RRB- cord-015369-72cjogxz 1944 18 or or CC cord-015369-72cjogxz 1944 19 cisplatin cisplatin NN cord-015369-72cjogxz 1944 20 ( ( -LRB- cord-015369-72cjogxz 1944 21 50 50 CD cord-015369-72cjogxz 1944 22 mg mg NNP cord-015369-72cjogxz 1944 23 / / SYM cord-015369-72cjogxz 1944 24 m m NNP cord-015369-72cjogxz 1944 25 2 2 CD cord-015369-72cjogxz 1944 26 ) ) -RRB- cord-015369-72cjogxz 1944 27 at at IN cord-015369-72cjogxz 1944 28 42 42 CD cord-015369-72cjogxz 1944 29 C c NN cord-015369-72cjogxz 1944 30 for for IN cord-015369-72cjogxz 1944 31 90 90 CD cord-015369-72cjogxz 1944 32 min min NN cord-015369-72cjogxz 1944 33 . . . cord-015369-72cjogxz 1945 1 Results result NNS cord-015369-72cjogxz 1945 2 . . . cord-015369-72cjogxz 1946 1 Indications indication NNS cord-015369-72cjogxz 1946 2 for for IN cord-015369-72cjogxz 1946 3 CRS CRS NNP cord-015369-72cjogxz 1946 4 / / SYM cord-015369-72cjogxz 1946 5 HIPEC HIPEC NNP cord-015369-72cjogxz 1946 6 were be VBD cord-015369-72cjogxz 1946 7 pseudomyxoma pseudomyxoma NNP cord-015369-72cjogxz 1946 8 peritonei peritonei NNP cord-015369-72cjogxz 1946 9 ( ( -LRB- cord-015369-72cjogxz 1946 10 32 32 CD cord-015369-72cjogxz 1946 11 patients patient NNS cord-015369-72cjogxz 1946 12 ) ) -RRB- cord-015369-72cjogxz 1946 13 , , , cord-015369-72cjogxz 1946 14 colorectal colorectal JJ cord-015369-72cjogxz 1946 15 cancer cancer NN cord-015369-72cjogxz 1946 16 ( ( -LRB- cord-015369-72cjogxz 1946 17 12 12 CD cord-015369-72cjogxz 1946 18 ) ) -RRB- cord-015369-72cjogxz 1946 19 , , , cord-015369-72cjogxz 1946 20 ovarian ovarian JJ cord-015369-72cjogxz 1946 21 cancer cancer NN cord-015369-72cjogxz 1946 22 ( ( -LRB- cord-015369-72cjogxz 1946 23 26 26 CD cord-015369-72cjogxz 1946 24 ) ) -RRB- cord-015369-72cjogxz 1946 25 , , , cord-015369-72cjogxz 1946 26 mesothelioma mesothelioma NN cord-015369-72cjogxz 1946 27 ( ( -LRB- cord-015369-72cjogxz 1946 28 4 4 CD cord-015369-72cjogxz 1946 29 ) ) -RRB- cord-015369-72cjogxz 1946 30 and and CC cord-015369-72cjogxz 1946 31 other other JJ cord-015369-72cjogxz 1946 32 rare rare JJ cord-015369-72cjogxz 1946 33 tumors tumor NNS cord-015369-72cjogxz 1946 34 ( ( -LRB- cord-015369-72cjogxz 1946 35 6 6 CD cord-015369-72cjogxz 1946 36 ) ) -RRB- cord-015369-72cjogxz 1946 37 . . . cord-015369-72cjogxz 1947 1 Median median JJ cord-015369-72cjogxz 1947 2 age age NN cord-015369-72cjogxz 1947 3 of of IN cord-015369-72cjogxz 1947 4 the the DT cord-015369-72cjogxz 1947 5 patients patient NNS cord-015369-72cjogxz 1947 6 was be VBD cord-015369-72cjogxz 1947 7 57 57 CD cord-015369-72cjogxz 1947 8 years year NNS cord-015369-72cjogxz 1947 9 , , , cord-015369-72cjogxz 1947 10 with with IN cord-015369-72cjogxz 1947 11 31 31 CD cord-015369-72cjogxz 1947 12 % % NN cord-015369-72cjogxz 1947 13 males male NNS cord-015369-72cjogxz 1947 14 and and CC cord-015369-72cjogxz 1947 15 69 69 CD cord-015369-72cjogxz 1947 16 % % NN cord-015369-72cjogxz 1947 17 females female NNS cord-015369-72cjogxz 1947 18 . . . cord-015369-72cjogxz 1948 1 The the DT cord-015369-72cjogxz 1948 2 mean mean JJ cord-015369-72cjogxz 1948 3 and and CC cord-015369-72cjogxz 1948 4 median median JJ cord-015369-72cjogxz 1948 5 surgical surgical JJ cord-015369-72cjogxz 1948 6 time time NN cord-015369-72cjogxz 1948 7 was be VBD cord-015369-72cjogxz 1948 8 510 510 CD cord-015369-72cjogxz 1948 9 min min NN cord-015369-72cjogxz 1948 10 and and CC cord-015369-72cjogxz 1948 11 median median JJ cord-015369-72cjogxz 1948 12 postoperative postoperative JJ cord-015369-72cjogxz 1948 13 hospitalization hospitalization NN cord-015369-72cjogxz 1948 14 24 24 CD cord-015369-72cjogxz 1948 15 days day NNS cord-015369-72cjogxz 1948 16 . . . cord-015369-72cjogxz 1949 1 In in IN cord-015369-72cjogxz 1949 2 - - HYPH cord-015369-72cjogxz 1949 3 hospital hospital NN cord-015369-72cjogxz 1949 4 mortality mortality NN cord-015369-72cjogxz 1949 5 was be VBD cord-015369-72cjogxz 1949 6 3.8 3.8 CD cord-015369-72cjogxz 1949 7 % % NN cord-015369-72cjogxz 1949 8 . . . cord-015369-72cjogxz 1950 1 18 18 CD cord-015369-72cjogxz 1950 2 % % NN cord-015369-72cjogxz 1950 3 of of IN cord-015369-72cjogxz 1950 4 the the DT cord-015369-72cjogxz 1950 5 PMP PMP NNP cord-015369-72cjogxz 1950 6 patients patient NNS cord-015369-72cjogxz 1950 7 had have VBD cord-015369-72cjogxz 1950 8 a a DT cord-015369-72cjogxz 1950 9 second second JJ cord-015369-72cjogxz 1950 10 CRS CRS NNP cord-015369-72cjogxz 1950 11 / / SYM cord-015369-72cjogxz 1950 12 HIPEC HIPEC NNP cord-015369-72cjogxz 1950 13 treatment treatment NN cord-015369-72cjogxz 1950 14 18 18 CD cord-015369-72cjogxz 1950 15 months month NNS cord-015369-72cjogxz 1950 16 ( ( -LRB- cord-015369-72cjogxz 1950 17 median median NN cord-015369-72cjogxz 1950 18 ) ) -RRB- cord-015369-72cjogxz 1950 19 after after IN cord-015369-72cjogxz 1950 20 the the DT cord-015369-72cjogxz 1950 21 primary primary JJ cord-015369-72cjogxz 1950 22 treatment treatment NN cord-015369-72cjogxz 1950 23 . . . cord-015369-72cjogxz 1951 1 Major major JJ cord-015369-72cjogxz 1951 2 complications complication NNS cord-015369-72cjogxz 1951 3 requiring require VBG cord-015369-72cjogxz 1951 4 re re NN cord-015369-72cjogxz 1951 5 - - NN cord-015369-72cjogxz 1951 6 surgery surgery NN cord-015369-72cjogxz 1951 7 occurred occur VBD cord-015369-72cjogxz 1951 8 in in IN cord-015369-72cjogxz 1951 9 23 23 CD cord-015369-72cjogxz 1951 10 % % NN cord-015369-72cjogxz 1951 11 . . . cord-015369-72cjogxz 1952 1 Over over RB cord-015369-72cjogxz 1952 2 - - HYPH cord-015369-72cjogxz 1952 3 all all DT cord-015369-72cjogxz 1952 4 survival survival NN cord-015369-72cjogxz 1952 5 for for IN cord-015369-72cjogxz 1952 6 pseudomyxoma pseudomyxoma NNP cord-015369-72cjogxz 1952 7 peritonei peritonei NNP cord-015369-72cjogxz 1952 8 patients patient NNS cord-015369-72cjogxz 1952 9 after after IN cord-015369-72cjogxz 1952 10 primary primary JJ cord-015369-72cjogxz 1952 11 surgery surgery NN cord-015369-72cjogxz 1952 12 was be VBD cord-015369-72cjogxz 1952 13 91 91 CD cord-015369-72cjogxz 1952 14 % % NN cord-015369-72cjogxz 1952 15 after after IN cord-015369-72cjogxz 1952 16 1 1 CD cord-015369-72cjogxz 1952 17 year year NN cord-015369-72cjogxz 1952 18 and and CC cord-015369-72cjogxz 1952 19 52 52 CD cord-015369-72cjogxz 1952 20 % % NN cord-015369-72cjogxz 1952 21 after after IN cord-015369-72cjogxz 1952 22 5 5 CD cord-015369-72cjogxz 1952 23 years year NNS cord-015369-72cjogxz 1952 24 , , , cord-015369-72cjogxz 1952 25 for for IN cord-015369-72cjogxz 1952 26 patients patient NNS cord-015369-72cjogxz 1952 27 with with IN cord-015369-72cjogxz 1952 28 ovarian ovarian JJ cord-015369-72cjogxz 1952 29 cancer cancer NN cord-015369-72cjogxz 1952 30 88 88 CD cord-015369-72cjogxz 1952 31 % % NN cord-015369-72cjogxz 1952 32 and and CC cord-015369-72cjogxz 1952 33 59 59 CD cord-015369-72cjogxz 1952 34 % % NN cord-015369-72cjogxz 1952 35 , , , cord-015369-72cjogxz 1952 36 respectively respectively RB cord-015369-72cjogxz 1952 37 . . . cord-015369-72cjogxz 1953 1 Conclusions conclusion NNS cord-015369-72cjogxz 1953 2 . . . cord-015369-72cjogxz 1954 1 CRS CRS NNP cord-015369-72cjogxz 1954 2 combined combine VBN cord-015369-72cjogxz 1954 3 with with IN cord-015369-72cjogxz 1954 4 HIPEC HIPEC NNP cord-015369-72cjogxz 1954 5 is be VBZ cord-015369-72cjogxz 1954 6 a a DT cord-015369-72cjogxz 1954 7 valuable valuable JJ cord-015369-72cjogxz 1954 8 addition addition NN cord-015369-72cjogxz 1954 9 to to IN cord-015369-72cjogxz 1954 10 oncological oncological JJ cord-015369-72cjogxz 1954 11 surgery surgery NN cord-015369-72cjogxz 1954 12 . . . cord-015369-72cjogxz 1955 1 Due due IN cord-015369-72cjogxz 1955 2 to to IN cord-015369-72cjogxz 1955 3 the the DT cord-015369-72cjogxz 1955 4 high high JJ cord-015369-72cjogxz 1955 5 morbidity morbidity NN cord-015369-72cjogxz 1955 6 , , , cord-015369-72cjogxz 1955 7 patients patient NNS cord-015369-72cjogxz 1955 8 have have VBP cord-015369-72cjogxz 1955 9 to to TO cord-015369-72cjogxz 1955 10 be be VB cord-015369-72cjogxz 1955 11 carefully carefully RB cord-015369-72cjogxz 1955 12 selected select VBN cord-015369-72cjogxz 1955 13 and and CC cord-015369-72cjogxz 1955 14 surgeons surgeon NNS cord-015369-72cjogxz 1955 15 have have VBP cord-015369-72cjogxz 1955 16 to to TO cord-015369-72cjogxz 1955 17 learn learn VB cord-015369-72cjogxz 1955 18 which which WDT cord-015369-72cjogxz 1955 19 patients patient NNS cord-015369-72cjogxz 1955 20 can can MD cord-015369-72cjogxz 1955 21 profit profit VB cord-015369-72cjogxz 1955 22 from from IN cord-015369-72cjogxz 1955 23 the the DT cord-015369-72cjogxz 1955 24 treatment treatment NN cord-015369-72cjogxz 1955 25 . . . cord-015369-72cjogxz 1956 1 The the DT cord-015369-72cjogxz 1956 2 list list NN cord-015369-72cjogxz 1956 3 of of IN cord-015369-72cjogxz 1956 4 indications indication NNS cord-015369-72cjogxz 1956 5 is be VBZ cord-015369-72cjogxz 1956 6 still still RB cord-015369-72cjogxz 1956 7 expanding expand VBG cord-015369-72cjogxz 1956 8 and and CC cord-015369-72cjogxz 1956 9 the the DT cord-015369-72cjogxz 1956 10 outcome outcome NN cord-015369-72cjogxz 1956 11 continues continue VBZ cord-015369-72cjogxz 1956 12 to to TO cord-015369-72cjogxz 1956 13 improve improve VB cord-015369-72cjogxz 1956 14 , , , cord-015369-72cjogxz 1956 15 particularly particularly RB cord-015369-72cjogxz 1956 16 at at IN cord-015369-72cjogxz 1956 17 high high JJ cord-015369-72cjogxz 1956 18 volume volume NN cord-015369-72cjogxz 1956 19 centers center NNS cord-015369-72cjogxz 1956 20 specializing specialize VBG cord-015369-72cjogxz 1956 21 in in IN cord-015369-72cjogxz 1956 22 this this DT cord-015369-72cjogxz 1956 23 treatment treatment NN cord-015369-72cjogxz 1956 24 . . . cord-015369-72cjogxz 1957 1 Die die VB cord-015369-72cjogxz 1957 2 praeoperative praeoperative JJ cord-015369-72cjogxz 1957 3 kombinierte kombinierte NNP cord-015369-72cjogxz 1957 4 Radio Radio NNP cord-015369-72cjogxz 1957 5 / / SYM cord-015369-72cjogxz 1957 6 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 1957 7 beim beim NNP cord-015369-72cjogxz 1958 1 Rektumkarzinom Rektumkarzinom NNP cord-015369-72cjogxz 1958 2 ab ab NN cord-015369-72cjogxz 1958 3 dem dem NNP cord-015369-72cjogxz 1958 4 Stadium Stadium NNP cord-015369-72cjogxz 1958 5 T3 T3 NNP cord-015369-72cjogxz 1958 6 bzw bzw NNP cord-015369-72cjogxz 1958 7 . . . cord-015369-72cjogxz 1959 1 Nþ Nþ NNP cord-015369-72cjogxz 1959 2 gilt gilt NN cord-015369-72cjogxz 1959 3 heute heute NNP cord-015369-72cjogxz 1959 4 als als NNP cord-015369-72cjogxz 1959 5 standardisiertes standardisiertes NNP cord-015369-72cjogxz 1959 6 neoadjuvantes neoadjuvantes NNP cord-015369-72cjogxz 1959 7 Therapiekonzept Therapiekonzept NNP cord-015369-72cjogxz 1959 8 . . . cord-015369-72cjogxz 1960 1 Voraussetzung Voraussetzung NNP cord-015369-72cjogxz 1960 2 ist ist NN cord-015369-72cjogxz 1961 1 ein ein NNP cord-015369-72cjogxz 1961 2 exaktes exakte VBZ cord-015369-72cjogxz 1961 3 praeoperatives praeoperatives NNP cord-015369-72cjogxz 1962 1 Staging stage VBG cord-015369-72cjogxz 1962 2 um um UH cord-015369-72cjogxz 1962 3 ein ein NNP cord-015369-72cjogxz 1962 4 Overtreatment Overtreatment NNP cord-015369-72cjogxz 1962 5 zu zu NNP cord-015369-72cjogxz 1962 6 vermeiden vermeiden NNP cord-015369-72cjogxz 1962 7 . . . cord-015369-72cjogxz 1963 1 In in IN cord-015369-72cjogxz 1963 2 den den NNP cord-015369-72cjogxz 1963 3 letzten letzten NNP cord-015369-72cjogxz 1963 4 Jahren Jahren NNP cord-015369-72cjogxz 1963 5 werden werden NNP cord-015369-72cjogxz 1963 6 vor vor NNP cord-015369-72cjogxz 1964 1 allem allem NNP cord-015369-72cjogxz 1964 2 unter unter NNP cord-015369-72cjogxz 1964 3 Chirurgen Chirurgen NNP cord-015369-72cjogxz 1964 4 vermehrt vermehrt NN cord-015369-72cjogxz 1965 1 Stimmen Stimmen NNP cord-015369-72cjogxz 1965 2 laut laut NNP cord-015369-72cjogxz 1965 3 um um UH cord-015369-72cjogxz 1965 4 durch durch NNP cord-015369-72cjogxz 1965 5 eine eine NNP cord-015369-72cjogxz 1965 6 exaktere exaktere NNP cord-015369-72cjogxz 1965 7 Aussage Aussage NNP cord-015369-72cjogxz 1965 8 der der NNP cord-015369-72cjogxz 1965 9 Infiltrationstiefe Infiltrationstiefe NNP cord-015369-72cjogxz 1965 10 in in IN cord-015369-72cjogxz 1965 11 Hinblick Hinblick NNP cord-015369-72cjogxz 1965 12 auf auf NNP cord-015369-72cjogxz 1965 13 die die VBP cord-015369-72cjogxz 1965 14 mesorektale mesorektale JJ cord-015369-72cjogxz 1965 15 Schicht schicht NN cord-015369-72cjogxz 1966 1 und und NNP cord-015369-72cjogxz 1966 2 eine eine NNP cord-015369-72cjogxz 1966 3 hohe hohe NNP cord-015369-72cjogxz 1967 1 chirurgische chirurgische NNP cord-015369-72cjogxz 1967 2 Qualität Qualität NNP cord-015369-72cjogxz 1967 3 die die VBP cord-015369-72cjogxz 1967 4 Anzahl Anzahl NNP cord-015369-72cjogxz 1967 5 der der NNP cord-015369-72cjogxz 1967 6 erforderlichen erforderlichen NNS cord-015369-72cjogxz 1968 1 Bestrahlungen Bestrahlungen NNP cord-015369-72cjogxz 1968 2 zu zu NNP cord-015369-72cjogxz 1968 3 vermindern vermindern NNP cord-015369-72cjogxz 1968 4 . . . cord-015369-72cjogxz 1969 1 Wir Wir NNP cord-015369-72cjogxz 1969 2 berichten berichten NNP cord-015369-72cjogxz 1969 3 anhand anhand NNP cord-015369-72cjogxz 1969 4 der der NNP cord-015369-72cjogxz 1969 5 prospektiven prospektiven NNP cord-015369-72cjogxz 1969 6 colorektalen colorektalen NNP cord-015369-72cjogxz 1970 1 Datenerfassung Datenerfassung NNP cord-015369-72cjogxz 1970 2 der der NNP cord-015369-72cjogxz 1970 3 Patienten Patienten NNP cord-015369-72cjogxz 1971 1 an an DT cord-015369-72cjogxz 1971 2 der der NN cord-015369-72cjogxz 1971 3 Universitätsklinik Universitätsklinik NNP cord-015369-72cjogxz 1971 4 für für IN cord-015369-72cjogxz 1971 5 Chirurgie Chirurgie NNP cord-015369-72cjogxz 1971 6 der der NNP cord-015369-72cjogxz 1971 7 PMU PMU NNP cord-015369-72cjogxz 1971 8 Salzburg Salzburg NNP cord-015369-72cjogxz 1971 9 aus aus NNP cord-015369-72cjogxz 1971 10 den den NNP cord-015369-72cjogxz 1971 11 Jahren Jahren NNP cord-015369-72cjogxz 1971 12 2003 2003 CD cord-015369-72cjogxz 1971 13 - - SYM cord-015369-72cjogxz 1971 14 2008 2008 CD cord-015369-72cjogxz 1972 1 über über NNP cord-015369-72cjogxz 1972 2 unsere unsere NNP cord-015369-72cjogxz 1973 1 onkologischen onkologischen NNP cord-015369-72cjogxz 1973 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 1973 3 , , , cord-015369-72cjogxz 1973 4 Operationsverfahren Operationsverfahren NNP cord-015369-72cjogxz 1973 5 , , , cord-015369-72cjogxz 1973 6 Kontinenzerhaltungsraten Kontinenzerhaltungsraten NNP cord-015369-72cjogxz 1973 7 , , , cord-015369-72cjogxz 1974 1 Morbiditäts Morbiditäts NNP cord-015369-72cjogxz 1974 2 - - HYPH cord-015369-72cjogxz 1974 3 und und JJ cord-015369-72cjogxz 1974 4 Mortalitätsstatistik Mortalitätsstatistik NNP cord-015369-72cjogxz 1975 1 und und NNP cord-015369-72cjogxz 1976 1 Tumorremissionsraten Tumorremissionsraten NNP cord-015369-72cjogxz 1976 2 auf auf NNP cord-015369-72cjogxz 1976 3 das das NNP cord-015369-72cjogxz 1976 4 strikt strikt NN cord-015369-72cjogxz 1976 5 eingehaltene eingehaltene NNP cord-015369-72cjogxz 1976 6 interdisziplinäre interdisziplinäre NNP cord-015369-72cjogxz 1976 7 neoadjuvante neoadjuvante NNP cord-015369-72cjogxz 1976 8 Therapiekonzept Therapiekonzept NNP cord-015369-72cjogxz 1976 9 . . . cord-015369-72cjogxz 1977 1 Anhand Anhand NNP cord-015369-72cjogxz 1977 2 unserer unserer JJ cord-015369-72cjogxz 1977 3 erhobenen erhobenen NNP cord-015369-72cjogxz 1978 1 Daten Daten NNP cord-015369-72cjogxz 1978 2 mit mit VBD cord-015369-72cjogxz 1978 3 international international JJ cord-015369-72cjogxz 1978 4 vergleichbaren vergleichbaren NNP cord-015369-72cjogxz 1978 5 onkologischen onkologischen NNP cord-015369-72cjogxz 1978 6 Resultaten Resultaten NNP cord-015369-72cjogxz 1978 7 , , , cord-015369-72cjogxz 1978 8 akzeptabler akzeptabler NN cord-015369-72cjogxz 1978 9 Morbidität Morbidität NNP cord-015369-72cjogxz 1978 10 und und IN cord-015369-72cjogxz 1978 11 zufriedenstellenden zufriedenstellenden NNP cord-015369-72cjogxz 1978 12 funktionellen funktionellen NNP cord-015369-72cjogxz 1979 1 Ergebnissen Ergebnissen NNP cord-015369-72cjogxz 1979 2 wollen wollen NNP cord-015369-72cjogxz 1979 3 wir wir NNP cord-015369-72cjogxz 1979 4 die die VB cord-015369-72cjogxz 1980 1 Sinnhaftigkeit Sinnhaftigkeit NNP cord-015369-72cjogxz 1980 2 dieses dieses NN cord-015369-72cjogxz 1980 3 Behandlungsalgorythmus Behandlungsalgorythmus NNP cord-015369-72cjogxz 1980 4 unterstreichen unterstreichen NNS cord-015369-72cjogxz 1980 5 . . . cord-015369-72cjogxz 1981 1 Stellenwert Stellenwert NNP cord-015369-72cjogxz 1981 2 der der NNP cord-015369-72cjogxz 1981 3 Radiotherapie Radiotherapie NNP cord-015369-72cjogxz 1982 1 i -PRON- PRP cord-015369-72cjogxz 1982 2 m be VBP cord-015369-72cjogxz 1983 1 onkologischen onkologischen NNP cord-015369-72cjogxz 1984 1 Therapiemanagement Therapiemanagement NNP cord-015369-72cjogxz 1984 2 Die Die NNP cord-015369-72cjogxz 1984 3 Radiotherapie radiotherapie NN cord-015369-72cjogxz 1985 1 nimmt nimmt NNP cord-015369-72cjogxz 1985 2 einen einen NNP cord-015369-72cjogxz 1985 3 fixen fixen NNP cord-015369-72cjogxz 1985 4 Stellenwert Stellenwert NNP cord-015369-72cjogxz 1985 5 in in IN cord-015369-72cjogxz 1985 6 der der NNP cord-015369-72cjogxz 1985 7 onkologischen onkologischen NNP cord-015369-72cjogxz 1985 8 Gesamtbehandlung Gesamtbehandlung NNP cord-015369-72cjogxz 1985 9 ein ein NNP cord-015369-72cjogxz 1985 10 . . . cord-015369-72cjogxz 1986 1 Der Der NNP cord-015369-72cjogxz 1986 2 Einsatz Einsatz NNP cord-015369-72cjogxz 1986 3 der der NN cord-015369-72cjogxz 1986 4 Strahlentherapie Strahlentherapie NNP cord-015369-72cjogxz 1986 5 wird wird NNP cord-015369-72cjogxz 1987 1 nach nach NNP cord-015369-72cjogxz 1987 2 interdisziplinärer interdisziplinärer NNP cord-015369-72cjogxz 1988 1 Entscheidung Entscheidung NNP cord-015369-72cjogxz 1988 2 -abhängig -abhängig HYPH cord-015369-72cjogxz 1988 3 von von NNP cord-015369-72cjogxz 1988 4 der der NNP cord-015369-72cjogxz 1988 5 Tumorentität Tumorentität NNP cord-015369-72cjogxz 1988 6 , , , cord-015369-72cjogxz 1988 7 der der NNP cord-015369-72cjogxz 1988 8 Tumorklassifikation Tumorklassifikation NNP cord-015369-72cjogxz 1988 9 , , , cord-015369-72cjogxz 1988 10 der der NNP cord-015369-72cjogxz 1988 11 Tumorlokalisation Tumorlokalisation NNP cord-015369-72cjogxz 1988 12 , , , cord-015369-72cjogxz 1988 13 der der NNP cord-015369-72cjogxz 1988 14 geplanten geplanten VBN cord-015369-72cjogxz 1988 15 Behandlungsregime Behandlungsregime NNP cord-015369-72cjogxz 1988 16 und und IN cord-015369-72cjogxz 1988 17 der der NNP cord-015369-72cjogxz 1988 18 Patientenbefindlichkeit Patientenbefindlichkeit NNP cord-015369-72cjogxz 1988 19 -zeitlich -zeitlich HYPH cord-015369-72cjogxz 1988 20 koordiniert koordiniert NNP cord-015369-72cjogxz 1988 21 . . . cord-015369-72cjogxz 1989 1 Die die VB cord-015369-72cjogxz 1989 2 postoperative postoperative JJ cord-015369-72cjogxz 1989 3 Strahlentherapie Strahlentherapie NNP cord-015369-72cjogxz 1989 4 wird wird NNP cord-015369-72cjogxz 1989 5 generell generell NNP cord-015369-72cjogxz 1989 6 am be VBP cord-015369-72cjogxz 1989 7 häufigsten häufigsten NNP cord-015369-72cjogxz 1989 8 eingesetzt eingesetzt NNP cord-015369-72cjogxz 1989 9 . . . cord-015369-72cjogxz 1990 1 Bei Bei NNP cord-015369-72cjogxz 1990 2 gastrointestinalen gastrointestinalen NNP cord-015369-72cjogxz 1990 3 Tumoren Tumoren NNP cord-015369-72cjogxz 1990 4 , , , cord-015369-72cjogxz 1990 5 hier hier NNP cord-015369-72cjogxz 1990 6 vor vor NNP cord-015369-72cjogxz 1991 1 allem allem NNP cord-015369-72cjogxz 1991 2 beim beim NNP cord-015369-72cjogxz 1991 3 Rektumkarzinom Rektumkarzinom NNP cord-015369-72cjogxz 1992 1 , , , cord-015369-72cjogxz 1992 2 hat hat NN cord-015369-72cjogxz 1992 3 die die VBP cord-015369-72cjogxz 1992 4 neoadjuvante neoadjuvante JJ cord-015369-72cjogxz 1993 1 Radiotherapie Radiotherapie NNP cord-015369-72cjogxz 1993 2 die die VBP cord-015369-72cjogxz 1993 3 nebenwirkungsreichere nebenwirkungsreichere JJ cord-015369-72cjogxz 1993 4 postoperative postoperative JJ cord-015369-72cjogxz 1993 5 Bestrahlung Bestrahlung NNP cord-015369-72cjogxz 1993 6 weitgehend weitgehend NNP cord-015369-72cjogxz 1993 7 abgelöst abgelöst NNP cord-015369-72cjogxz 1993 8 . . . cord-015369-72cjogxz 1994 1 Durch Durch NNP cord-015369-72cjogxz 1994 2 das das NNP cord-015369-72cjogxz 1995 1 neoadjuvante neoadjuvante NNP cord-015369-72cjogxz 1995 2 Therapiemanagement Therapiemanagement NNP cord-015369-72cjogxz 1995 3 ist ist NNP cord-015369-72cjogxz 1995 4 ein ein NNP cord-015369-72cjogxz 1995 5 deutlich deutlich NNP cord-015369-72cjogxz 1995 6 höheres höheres NNP cord-015369-72cjogxz 1996 1 Tumoransprechen Tumoransprechen NNP cord-015369-72cjogxz 1996 2 durch durch NNP cord-015369-72cjogxz 1996 3 die die VBP cord-015369-72cjogxz 1996 4 bessere bessere NNP cord-015369-72cjogxz 1996 5 Tumoroxygenierung Tumoroxygenierung NNP cord-015369-72cjogxz 1996 6 bei bei NNP cord-015369-72cjogxz 1996 7 deutlich deutlich NNP cord-015369-72cjogxz 1996 8 geringeren geringeren NNP cord-015369-72cjogxz 1997 1 Spätfolgen Spätfolgen NNP cord-015369-72cjogxz 1997 2 , , , cord-015369-72cjogxz 1997 3 vor vor NNP cord-015369-72cjogxz 1997 4 allem allem NNP cord-015369-72cjogxz 1997 5 i -PRON- PRP cord-015369-72cjogxz 1997 6 m be VBP cord-015369-72cjogxz 1997 7 Dünndarmbereich Dünndarmbereich NNP cord-015369-72cjogxz 1997 8 , , , cord-015369-72cjogxz 1997 9 bestätigt bestätigt NNP cord-015369-72cjogxz 1997 10 . . . cord-015369-72cjogxz 1998 1 Die die VB cord-015369-72cjogxz 1998 2 Entscheidung Entscheidung NNP cord-015369-72cjogxz 1998 3 über über NNP cord-015369-72cjogxz 1998 4 den den NN cord-015369-72cjogxz 1998 5 Einsatz Einsatz NNP cord-015369-72cjogxz 1998 6 einer einer NNP cord-015369-72cjogxz 1998 7 Kurzzeitvorbestrahlung Kurzzeitvorbestrahlung NNP cord-015369-72cjogxz 1998 8 ( ( -LRB- cord-015369-72cjogxz 1998 9 5 5 CD cord-015369-72cjogxz 1998 10 Â â NN cord-015369-72cjogxz 1998 11 5 5 CD cord-015369-72cjogxz 1998 12 Gy Gy NNP cord-015369-72cjogxz 1998 13 in in IN cord-015369-72cjogxz 1998 14 5 5 CD cord-015369-72cjogxz 1998 15 Tagen Tagen NNP cord-015369-72cjogxz 1998 16 ) ) -RRB- cord-015369-72cjogxz 1999 1 oder oder NNP cord-015369-72cjogxz 1999 2 einer einer NNP cord-015369-72cjogxz 1999 3 Langzeitbestrahlung Langzeitbestrahlung NNP cord-015369-72cjogxz 1999 4 ( ( -LRB- cord-015369-72cjogxz 1999 5 28 28 CD cord-015369-72cjogxz 1999 6 Â â NN cord-015369-72cjogxz 1999 7 1,8 1,8 CD cord-015369-72cjogxz 1999 8 Gy Gy NNP cord-015369-72cjogxz 1999 9 in in IN cord-015369-72cjogxz 1999 10 5 5 CD cord-015369-72cjogxz 1999 11 Wochen Wochen NNP cord-015369-72cjogxz 1999 12 ) ) -RRB- cord-015369-72cjogxz 2000 1 ist ist NNP cord-015369-72cjogxz 2000 2 abhängig abhängig NNP cord-015369-72cjogxz 2000 3 von von NNP cord-015369-72cjogxz 2000 4 der der NNP cord-015369-72cjogxz 2000 5 Tumorgröße Tumorgröße NNP cord-015369-72cjogxz 2000 6 , , , cord-015369-72cjogxz 2000 7 Tumorlokalisation Tumorlokalisation NNP cord-015369-72cjogxz 2000 8 und und IN cord-015369-72cjogxz 2000 9 Notwendigkeit Notwendigkeit NNP cord-015369-72cjogxz 2000 10 einer einer NNP cord-015369-72cjogxz 2000 11 konkomitanten konkomitanten NNP cord-015369-72cjogxz 2000 12 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 2000 13 . . . cord-015369-72cjogxz 2001 1 Steht Steht NNP cord-015369-72cjogxz 2001 2 die die VBP cord-015369-72cjogxz 2001 3 Organ Organ NNP cord-015369-72cjogxz 2001 4 - - HYPH cord-015369-72cjogxz 2001 5 und und NNP cord-015369-72cjogxz 2001 6 Funktionserhaltung Funktionserhaltung NNP cord-015369-72cjogxz 2001 7 , , , cord-015369-72cjogxz 2001 8 vor vor NNP cord-015369-72cjogxz 2001 9 allem allem NNP cord-015369-72cjogxz 2001 10 beim beim NNP cord-015369-72cjogxz 2001 11 Analkarzinom Analkarzinom NNP cord-015369-72cjogxz 2001 12 , , , cord-015369-72cjogxz 2001 13 i -PRON- PRP cord-015369-72cjogxz 2001 14 m be VBP cord-015369-72cjogxz 2001 15 Vordergrund Vordergrund NNP cord-015369-72cjogxz 2001 16 , , , cord-015369-72cjogxz 2001 17 kommt kommt NNP cord-015369-72cjogxz 2001 18 die die VBP cord-015369-72cjogxz 2001 19 definitive definitive JJ cord-015369-72cjogxz 2001 20 Radiotherapie Radiotherapie NNP cord-015369-72cjogxz 2001 21 mit mit NNP cord-015369-72cjogxz 2001 22 oder oder NNP cord-015369-72cjogxz 2001 23 ohne ohne NNP cord-015369-72cjogxz 2001 24 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 2001 25 zum zum NNP cord-015369-72cjogxz 2001 26 Einsatz Einsatz NNP cord-015369-72cjogxz 2001 27 . . . cord-015369-72cjogxz 2002 1 Die die VB cord-015369-72cjogxz 2003 1 chirurgische chirurgische NNP cord-015369-72cjogxz 2003 2 Intervention Intervention NNP cord-015369-72cjogxz 2003 3 dient dient NNP cord-015369-72cjogxz 2003 4 bei bei NNP cord-015369-72cjogxz 2003 5 dieser dieser NNP cord-015369-72cjogxz 2003 6 Indikation Indikation NNP cord-015369-72cjogxz 2003 7 als als NNP cord-015369-72cjogxz 2003 8 Salvage Salvage NNP cord-015369-72cjogxz 2003 9 - - HYPH cord-015369-72cjogxz 2003 10 Methode Methode NNP cord-015369-72cjogxz 2003 11 . . . cord-015369-72cjogxz 2004 1 Der Der NNP cord-015369-72cjogxz 2004 2 intraoperative intraoperative JJ cord-015369-72cjogxz 2004 3 Einsatz Einsatz NNP cord-015369-72cjogxz 2004 4 der der NN cord-015369-72cjogxz 2004 5 Strahlentherapie Strahlentherapie NNP cord-015369-72cjogxz 2004 6 kann kann NNP cord-015369-72cjogxz 2004 7 abhängig abhängig NNP cord-015369-72cjogxz 2004 8 von von NNP cord-015369-72cjogxz 2004 9 der der NNP cord-015369-72cjogxz 2004 10 Entität Entität NNP cord-015369-72cjogxz 2004 11 und und IN cord-015369-72cjogxz 2004 12 den den NN cord-015369-72cjogxz 2004 13 gerätetechnischen gerätetechnischen NNP cord-015369-72cjogxz 2004 14 Möglichkeiten Möglichkeiten NNP cord-015369-72cjogxz 2004 15 eine eine NNP cord-015369-72cjogxz 2004 16 Behandlungsoption Behandlungsoption NNP cord-015369-72cjogxz 2004 17 darstellen darstellen NNS cord-015369-72cjogxz 2004 18 . . . cord-015369-72cjogxz 2005 1 Durch Durch NNP cord-015369-72cjogxz 2005 2 die die VBP cord-015369-72cjogxz 2006 1 moderne moderne NNP cord-015369-72cjogxz 2006 2 Gerätetechnik Gerätetechnik NNP cord-015369-72cjogxz 2006 3 gelangen gelangen NNP cord-015369-72cjogxz 2006 4 zunehmend zunehmend NNP cord-015369-72cjogxz 2006 5 Hochpräzisionsbestrahlungen Hochpräzisionsbestrahlungen NNP cord-015369-72cjogxz 2007 1 ( ( -LRB- cord-015369-72cjogxz 2007 2 Intensitätsmodulierte Intensitätsmodulierte NNP cord-015369-72cjogxz 2007 3 Radiotherapie Radiotherapie NNP cord-015369-72cjogxz 2007 4 , , , cord-015369-72cjogxz 2007 5 dynamische dynamische NNP cord-015369-72cjogxz 2007 6 arc arc NNP cord-015369-72cjogxz 2007 7 - - HYPH cord-015369-72cjogxz 2007 8 Radiotherapie Radiotherapie NNP cord-015369-72cjogxz 2007 9 ) ) -RRB- cord-015369-72cjogxz 2007 10 , , , cord-015369-72cjogxz 2007 11 unter unter NNP cord-015369-72cjogxz 2007 12 Anwendung Anwendung NNP cord-015369-72cjogxz 2007 13 moderner moderner NNPS cord-015369-72cjogxz 2007 14 Bilddarstellungen Bilddarstellungen NNP cord-015369-72cjogxz 2007 15 am be VBP cord-015369-72cjogxz 2007 16 Linearbeschleuniger Linearbeschleuniger NNP cord-015369-72cjogxz 2007 17 ( ( -LRB- cord-015369-72cjogxz 2007 18 Image image NN cord-015369-72cjogxz 2007 19 - - HYPH cord-015369-72cjogxz 2007 20 Guided Guided NNP cord-015369-72cjogxz 2007 21 - - HYPH cord-015369-72cjogxz 2007 22 Radiation Radiation NNP cord-015369-72cjogxz 2007 23 Therapy Therapy NNP cord-015369-72cjogxz 2007 24 ) ) -RRB- cord-015369-72cjogxz 2007 25 , , , cord-015369-72cjogxz 2007 26 zum zum NNP cord-015369-72cjogxz 2007 27 Einsatz Einsatz NNP cord-015369-72cjogxz 2007 28 . . . cord-015369-72cjogxz 2008 1 Background background NN cord-015369-72cjogxz 2008 2 . . . cord-015369-72cjogxz 2009 1 Postoperative postoperative JJ cord-015369-72cjogxz 2009 2 morbidity morbidity NN cord-015369-72cjogxz 2009 3 remains remain VBZ cord-015369-72cjogxz 2009 4 a a DT cord-015369-72cjogxz 2009 5 significant significant JJ cord-015369-72cjogxz 2009 6 clinical clinical JJ cord-015369-72cjogxz 2009 7 problem problem NN cord-015369-72cjogxz 2009 8 and and CC cord-015369-72cjogxz 2009 9 may may MD cord-015369-72cjogxz 2009 10 alter´long alter´long NNP cord-015369-72cjogxz 2009 11 term term NN cord-015369-72cjogxz 2009 12 outcome outcome NN cord-015369-72cjogxz 2009 13 particularly particularly RB cord-015369-72cjogxz 2009 14 after after IN cord-015369-72cjogxz 2009 15 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 2009 16 chemoradiation chemoradiation NN cord-015369-72cjogxz 2009 17 in in IN cord-015369-72cjogxz 2009 18 patients patient NNS cord-015369-72cjogxz 2009 19 with with IN cord-015369-72cjogxz 2009 20 locally locally RB cord-015369-72cjogxz 2009 21 advanced advanced JJ cord-015369-72cjogxz 2009 22 low low JJ cord-015369-72cjogxz 2009 23 rectal rectal JJ cord-015369-72cjogxz 2009 24 cancer cancer NN cord-015369-72cjogxz 2009 25 . . . cord-015369-72cjogxz 2010 1 The the DT cord-015369-72cjogxz 2010 2 aim aim NN cord-015369-72cjogxz 2010 3 of of IN cord-015369-72cjogxz 2010 4 the the DT cord-015369-72cjogxz 2010 5 present present JJ cord-015369-72cjogxz 2010 6 study study NN cord-015369-72cjogxz 2010 7 was be VBD cord-015369-72cjogxz 2010 8 to to TO cord-015369-72cjogxz 2010 9 identify identify VB cord-015369-72cjogxz 2010 10 a a DT cord-015369-72cjogxz 2010 11 potential potential JJ cord-015369-72cjogxz 2010 12 long long JJ cord-015369-72cjogxz 2010 13 - - HYPH cord-015369-72cjogxz 2010 14 term term NN cord-015369-72cjogxz 2010 15 effect effect NN cord-015369-72cjogxz 2010 16 of of IN cord-015369-72cjogxz 2010 17 postoperative postoperative JJ cord-015369-72cjogxz 2010 18 morbidity morbidity NN cord-015369-72cjogxz 2010 19 . . . cord-015369-72cjogxz 2011 1 Methods method NNS cord-015369-72cjogxz 2011 2 . . . cord-015369-72cjogxz 2012 1 Analysis analysis NN cord-015369-72cjogxz 2012 2 of of IN cord-015369-72cjogxz 2012 3 prospectively prospectively RB cord-015369-72cjogxz 2012 4 collected collect VBN cord-015369-72cjogxz 2012 5 data datum NNS cord-015369-72cjogxz 2012 6 of of IN cord-015369-72cjogxz 2012 7 ninety ninety CD cord-015369-72cjogxz 2012 8 consecutive consecutive JJ cord-015369-72cjogxz 2012 9 patients patient NNS cord-015369-72cjogxz 2012 10 who who WP cord-015369-72cjogxz 2012 11 underwent undergo VBD cord-015369-72cjogxz 2012 12 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 2012 13 chemoradiation chemoradiation NN cord-015369-72cjogxz 2012 14 and and CC cord-015369-72cjogxz 2012 15 curative curative JJ cord-015369-72cjogxz 2012 16 mesorectal mesorectal JJ cord-015369-72cjogxz 2012 17 excision excision NN cord-015369-72cjogxz 2012 18 for for IN cord-015369-72cjogxz 2012 19 locally locally RB cord-015369-72cjogxz 2012 20 advanced advanced JJ cord-015369-72cjogxz 2012 21 ( ( -LRB- cord-015369-72cjogxz 2012 22 cT3/4 ct3/4 XX cord-015369-72cjogxz 2013 1 , , , cord-015369-72cjogxz 2013 2 Nx Nx NNP cord-015369-72cjogxz 2013 3 , , , cord-015369-72cjogxz 2013 4 M0/1 M0/1 NNP cord-015369-72cjogxz 2013 5 ) ) -RRB- cord-015369-72cjogxz 2013 6 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 2013 7 of of IN cord-015369-72cjogxz 2013 8 the the DT cord-015369-72cjogxz 2013 9 mid mid JJ cord-015369-72cjogxz 2013 10 and and CC cord-015369-72cjogxz 2013 11 low low JJ cord-015369-72cjogxz 2013 12 third third NN cord-015369-72cjogxz 2013 13 of of IN cord-015369-72cjogxz 2013 14 the the DT cord-015369-72cjogxz 2013 15 rectum rectum NN cord-015369-72cjogxz 2013 16 during during IN cord-015369-72cjogxz 2013 17 a a DT cord-015369-72cjogxz 2013 18 seven seven CD cord-015369-72cjogxz 2013 19 - - HYPH cord-015369-72cjogxz 2013 20 year year NN cord-015369-72cjogxz 2013 21 period period NN cord-015369-72cjogxz 2013 22 ( ( -LRB- cord-015369-72cjogxz 2013 23 1996 1996 CD cord-015369-72cjogxz 2013 24 ) ) -RRB- cord-015369-72cjogxz 2013 25 ( ( -LRB- cord-015369-72cjogxz 2013 26 1997 1997 CD cord-015369-72cjogxz 2013 27 ) ) -RRB- cord-015369-72cjogxz 2014 1 ( ( -LRB- cord-015369-72cjogxz 2014 2 1998 1998 CD cord-015369-72cjogxz 2014 3 ) ) -RRB- cord-015369-72cjogxz 2015 1 ( ( -LRB- cord-015369-72cjogxz 2015 2 1999 1999 CD cord-015369-72cjogxz 2015 3 ) ) -RRB- cord-015369-72cjogxz 2016 1 ( ( -LRB- cord-015369-72cjogxz 2016 2 2000 2000 CD cord-015369-72cjogxz 2016 3 ) ) -RRB- cord-015369-72cjogxz 2017 1 ( ( -LRB- cord-015369-72cjogxz 2017 2 2001 2001 CD cord-015369-72cjogxz 2017 3 ) ) -RRB- cord-015369-72cjogxz 2017 4 ( ( -LRB- cord-015369-72cjogxz 2017 5 2002 2002 CD cord-015369-72cjogxz 2017 6 ) ) -RRB- cord-015369-72cjogxz 2017 7 . . . cord-015369-72cjogxz 2018 1 Results result NNS cord-015369-72cjogxz 2018 2 . . . cord-015369-72cjogxz 2019 1 Major major JJ cord-015369-72cjogxz 2019 2 postoperative postoperative JJ cord-015369-72cjogxz 2019 3 complications complication NNS cord-015369-72cjogxz 2019 4 occurred occur VBD cord-015369-72cjogxz 2019 5 in in IN cord-015369-72cjogxz 2019 6 17,8 17,8 CD cord-015369-72cjogxz 2019 7 % % NN cord-015369-72cjogxz 2019 8 and and CC cord-015369-72cjogxz 2019 9 minor minor JJ cord-015369-72cjogxz 2019 10 complications complication NNS cord-015369-72cjogxz 2019 11 in in IN cord-015369-72cjogxz 2019 12 26.6 26.6 CD cord-015369-72cjogxz 2019 13 % % NN cord-015369-72cjogxz 2019 14 of of IN cord-015369-72cjogxz 2019 15 patients patient NNS cord-015369-72cjogxz 2019 16 . . . cord-015369-72cjogxz 2020 1 Hospital hospital NN cord-015369-72cjogxz 2020 2 mortality mortality NN cord-015369-72cjogxz 2020 3 and and CC cord-015369-72cjogxz 2020 4 30-day 30-day CD cord-015369-72cjogxz 2020 5 mortality mortality NN cord-015369-72cjogxz 2020 6 was be VBD cord-015369-72cjogxz 2020 7 0 0 CD cord-015369-72cjogxz 2020 8 % % NN cord-015369-72cjogxz 2020 9 . . . cord-015369-72cjogxz 2021 1 Infectious infectious JJ cord-015369-72cjogxz 2021 2 complications complication NNS cord-015369-72cjogxz 2021 3 were be VBD cord-015369-72cjogxz 2021 4 seen see VBN cord-015369-72cjogxz 2021 5 in in IN cord-015369-72cjogxz 2021 6 34.5 34.5 CD cord-015369-72cjogxz 2021 7 % % NN cord-015369-72cjogxz 2021 8 . . . cord-015369-72cjogxz 2022 1 The the DT cord-015369-72cjogxz 2022 2 leading lead VBG cord-015369-72cjogxz 2022 3 causes cause NNS cord-015369-72cjogxz 2022 4 of of IN cord-015369-72cjogxz 2022 5 infectious infectious JJ cord-015369-72cjogxz 2022 6 complications complication NNS cord-015369-72cjogxz 2022 7 were be VBD cord-015369-72cjogxz 2022 8 anastomotic anastomotic JJ cord-015369-72cjogxz 2022 9 leakage leakage NN cord-015369-72cjogxz 2022 10 and and CC cord-015369-72cjogxz 2022 11 perineal perineal NN cord-015369-72cjogxz 2022 12 wound wound NN cord-015369-72cjogxz 2022 13 infection infection NN cord-015369-72cjogxz 2022 14 . . . cord-015369-72cjogxz 2023 1 Postoperative postoperative JJ cord-015369-72cjogxz 2023 2 morbidity morbidity NN cord-015369-72cjogxz 2023 3 was be VBD cord-015369-72cjogxz 2023 4 statistically statistically RB cord-015369-72cjogxz 2023 5 significantly significantly RB cord-015369-72cjogxz 2023 6 associated associate VBN cord-015369-72cjogxz 2023 7 with with IN cord-015369-72cjogxz 2023 8 gender gender NN cord-015369-72cjogxz 2023 9 ( ( -LRB- cord-015369-72cjogxz 2023 10 p p NN cord-015369-72cjogxz 2023 11 < < XX cord-015369-72cjogxz 2023 12 0.05 0.05 CD cord-015369-72cjogxz 2023 13 ) ) -RRB- cord-015369-72cjogxz 2023 14 , , , cord-015369-72cjogxz 2023 15 pre pre JJ cord-015369-72cjogxz 2023 16 - - JJ cord-015369-72cjogxz 2023 17 therapeutic therapeutic JJ cord-015369-72cjogxz 2023 18 haemoglobin haemoglobin NN cord-015369-72cjogxz 2023 19 level level NN cord-015369-72cjogxz 2023 20 ( ( -LRB- cord-015369-72cjogxz 2023 21 p p NN cord-015369-72cjogxz 2023 22 < < XX cord-015369-72cjogxz 2023 23 0.05 0.05 CD cord-015369-72cjogxz 2023 24 ) ) -RRB- cord-015369-72cjogxz 2023 25 , , , cord-015369-72cjogxz 2023 26 ASA ASA NNP cord-015369-72cjogxz 2023 27 score score NN cord-015369-72cjogxz 2023 28 ( ( -LRB- cord-015369-72cjogxz 2023 29 p p NN cord-015369-72cjogxz 2023 30 < < XX cord-015369-72cjogxz 2023 31 0.05 0.05 CD cord-015369-72cjogxz 2023 32 ) ) -RRB- cord-015369-72cjogxz 2023 33 , , , cord-015369-72cjogxz 2023 34 hospitalisation hospitalisation NN cord-015369-72cjogxz 2023 35 ( ( -LRB- cord-015369-72cjogxz 2023 36 p p NN cord-015369-72cjogxz 2023 37 < < XX cord-015369-72cjogxz 2023 38 0.001 0.001 CD cord-015369-72cjogxz 2023 39 ) ) -RRB- cord-015369-72cjogxz 2023 40 , , , cord-015369-72cjogxz 2023 41 and and CC cord-015369-72cjogxz 2023 42 clinical clinical JJ cord-015369-72cjogxz 2023 43 long long JJ cord-015369-72cjogxz 2023 44 - - HYPH cord-015369-72cjogxz 2023 45 time time NN cord-015369-72cjogxz 2023 46 course course NN cord-015369-72cjogxz 2023 47 ( ( -LRB- cord-015369-72cjogxz 2023 48 p p NN cord-015369-72cjogxz 2023 49 < < XX cord-015369-72cjogxz 2023 50 0.01 0.01 CD cord-015369-72cjogxz 2023 51 ) ) -RRB- cord-015369-72cjogxz 2023 52 . . . cord-015369-72cjogxz 2024 1 Moreover moreover RB cord-015369-72cjogxz 2024 2 , , , cord-015369-72cjogxz 2024 3 early early JJ cord-015369-72cjogxz 2024 4 postoperative postoperative JJ cord-015369-72cjogxz 2024 5 morbidity morbidity NN cord-015369-72cjogxz 2024 6 was be VBD cord-015369-72cjogxz 2024 7 proven prove VBN cord-015369-72cjogxz 2024 8 as as IN cord-015369-72cjogxz 2024 9 an an DT cord-015369-72cjogxz 2024 10 independent independent JJ cord-015369-72cjogxz 2024 11 prognostic prognostic JJ cord-015369-72cjogxz 2024 12 factor factor NN cord-015369-72cjogxz 2024 13 concerning concern VBG cord-015369-72cjogxz 2024 14 disease disease NN cord-015369-72cjogxz 2024 15 free free JJ cord-015369-72cjogxz 2024 16 ( ( -LRB- cord-015369-72cjogxz 2024 17 p p NN cord-015369-72cjogxz 2024 18 < < XX cord-015369-72cjogxz 2024 19 0.05 0.05 CD cord-015369-72cjogxz 2024 20 ) ) -RRB- cord-015369-72cjogxz 2024 21 and and CC cord-015369-72cjogxz 2024 22 overall overall JJ cord-015369-72cjogxz 2024 23 survival survival NN cord-015369-72cjogxz 2024 24 ( ( -LRB- cord-015369-72cjogxz 2024 25 p p NN cord-015369-72cjogxz 2024 26 < < XX cord-015369-72cjogxz 2024 27 0.05 0.05 CD cord-015369-72cjogxz 2024 28 ) ) -RRB- cord-015369-72cjogxz 2024 29 . . . cord-015369-72cjogxz 2025 1 Conclusions conclusion NNS cord-015369-72cjogxz 2025 2 . . . cord-015369-72cjogxz 2026 1 Early early JJ cord-015369-72cjogxz 2026 2 postoperative postoperative JJ cord-015369-72cjogxz 2026 3 morbidity morbidity NN cord-015369-72cjogxz 2026 4 in in IN cord-015369-72cjogxz 2026 5 patients patient NNS cord-015369-72cjogxz 2026 6 with with IN cord-015369-72cjogxz 2026 7 preoperative preoperative JJ cord-015369-72cjogxz 2026 8 chemoradiation chemoradiation NN cord-015369-72cjogxz 2026 9 due due JJ cord-015369-72cjogxz 2026 10 to to IN cord-015369-72cjogxz 2026 11 locally locally RB cord-015369-72cjogxz 2026 12 advanced advance VBN cord-015369-72cjogxz 2026 13 low low JJ cord-015369-72cjogxz 2026 14 rectal rectal JJ cord-015369-72cjogxz 2026 15 cancer cancer NN cord-015369-72cjogxz 2026 16 is be VBZ cord-015369-72cjogxz 2026 17 demonstrated demonstrate VBN cord-015369-72cjogxz 2026 18 as as IN cord-015369-72cjogxz 2026 19 an an DT cord-015369-72cjogxz 2026 20 independent independent JJ cord-015369-72cjogxz 2026 21 prognosticator prognosticator NN cord-015369-72cjogxz 2026 22 . . . cord-015369-72cjogxz 2027 1 Gender gender NN cord-015369-72cjogxz 2027 2 , , , cord-015369-72cjogxz 2027 3 pretherapeutic pretherapeutic NN cord-015369-72cjogxz 2027 4 haemoglobin haemoglobin NN cord-015369-72cjogxz 2027 5 level level NN cord-015369-72cjogxz 2027 6 , , , cord-015369-72cjogxz 2027 7 and and CC cord-015369-72cjogxz 2027 8 ASA ASA NNP cord-015369-72cjogxz 2027 9 score score NN cord-015369-72cjogxz 2027 10 indicate indicate VBP cord-015369-72cjogxz 2027 11 patients patient NNS cord-015369-72cjogxz 2027 12 at at IN cord-015369-72cjogxz 2027 13 risk risk NN cord-015369-72cjogxz 2027 14 for for IN cord-015369-72cjogxz 2027 15 early early JJ cord-015369-72cjogxz 2027 16 postoperative postoperative JJ cord-015369-72cjogxz 2027 17 complications complication NNS cord-015369-72cjogxz 2027 18 and and CC cord-015369-72cjogxz 2027 19 may may MD cord-015369-72cjogxz 2027 20 therefore therefore RB cord-015369-72cjogxz 2027 21 serve serve VB cord-015369-72cjogxz 2027 22 as as IN cord-015369-72cjogxz 2027 23 predictive predictive JJ cord-015369-72cjogxz 2027 24 features feature NNS cord-015369-72cjogxz 2027 25 . . . cord-015369-72cjogxz 2028 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2028 2 . . . cord-015369-72cjogxz 2029 1 Bei Bei NNP cord-015369-72cjogxz 2029 2 4 4 CD cord-015369-72cjogxz 2030 1 Patienten Patienten NNP cord-015369-72cjogxz 2030 2 mit mit NNP cord-015369-72cjogxz 2030 3 primären primären NNP cord-015369-72cjogxz 2030 4 cT2cN0-und cT2cN0-und NNP cord-015369-72cjogxz 2031 1 cT3cN1-Tumoren cT3cN1-Tumoren NNP cord-015369-72cjogxz 2031 2 wurde wurde NNP cord-015369-72cjogxz 2031 3 bei bei NNP cord-015369-72cjogxz 2031 4 klinischer klinischer NNP cord-015369-72cjogxz 2031 5 kompletter kompletter NNP cord-015369-72cjogxz 2031 6 Tumorremission Tumorremission NNP cord-015369-72cjogxz 2031 7 nach nach NN cord-015369-72cjogxz 2031 8 neoadjuvanter neoadjuvanter NN cord-015369-72cjogxz 2031 9 Radiochemotherapie Radiochemotherapie NNP cord-015369-72cjogxz 2031 10 ganz ganz NNP cord-015369-72cjogxz 2031 11 auf auf NNP cord-015369-72cjogxz 2031 12 die die VBP cord-015369-72cjogxz 2031 13 Operation Operation NNP cord-015369-72cjogxz 2031 14 verzichtet verzichtet NN cord-015369-72cjogxz 2031 15 . . . cord-015369-72cjogxz 2032 1 Nach Nach NNP cord-015369-72cjogxz 2032 2 einer einer NNP cord-015369-72cjogxz 2032 3 medianen medianen NNP cord-015369-72cjogxz 2033 1 Nachbeobachtungszeit Nachbeobachtungszeit NNP cord-015369-72cjogxz 2033 2 von von NNP cord-015369-72cjogxz 2034 1 22 22 CD cord-015369-72cjogxz 2034 2 Monaten Monaten NNP cord-015369-72cjogxz 2034 3 ( ( -LRB- cord-015369-72cjogxz 2034 4 9 9 CD cord-015369-72cjogxz 2034 5 - - SYM cord-015369-72cjogxz 2034 6 38 38 CD cord-015369-72cjogxz 2034 7 ) ) -RRB- cord-015369-72cjogxz 2034 8 ergaben ergaben NNP cord-015369-72cjogxz 2034 9 sich sich NNP cord-015369-72cjogxz 2034 10 lediglich lediglich NNP cord-015369-72cjogxz 2034 11 in in IN cord-015369-72cjogxz 2034 12 einem einem NNP cord-015369-72cjogxz 2034 13 Fall Fall NNP cord-015369-72cjogxz 2034 14 Fernmetastasen Fernmetastasen NNP cord-015369-72cjogxz 2034 15 der der NNP cord-015369-72cjogxz 2034 16 Leber Leber NNP cord-015369-72cjogxz 2035 1 und und IN cord-015369-72cjogxz 2035 2 Nebenniere Nebenniere NNP cord-015369-72cjogxz 2035 3 . . . cord-015369-72cjogxz 2036 1 Bei Bei NNP cord-015369-72cjogxz 2036 2 zwei zwei CD cord-015369-72cjogxz 2037 1 Patienten Patienten NNP cord-015369-72cjogxz 2037 2 mit mit NNP cord-015369-72cjogxz 2037 3 Lokalrezidiven Lokalrezidiven NNP cord-015369-72cjogxz 2037 4 jeweils jeweils NNP cord-015369-72cjogxz 2037 5 2 2 CD cord-015369-72cjogxz 2037 6 Jahre Jahre NNP cord-015369-72cjogxz 2038 1 nach nach NNP cord-015369-72cjogxz 2038 2 radikaler radikaler NNP cord-015369-72cjogxz 2038 3 Operation Operation NNP cord-015369-72cjogxz 2039 1 kam kam NNP cord-015369-72cjogxz 2040 1 es es XX cord-015369-72cjogxz 2040 2 zu zu NNP cord-015369-72cjogxz 2040 3 kompletter kompletter NNP cord-015369-72cjogxz 2040 4 Remission remission NN cord-015369-72cjogxz 2040 5 nach nach NNP cord-015369-72cjogxz 2040 6 Radiochemotherapie Radiochemotherapie NNP cord-015369-72cjogxz 2040 7 . . . cord-015369-72cjogxz 2041 1 Ein Ein NNP cord-015369-72cjogxz 2041 2 Patient Patient NNP cord-015369-72cjogxz 2041 3 blieb blieb NNP cord-015369-72cjogxz 2041 4 ohne ohne NNP cord-015369-72cjogxz 2041 5 Reoperation Reoperation NNP cord-015369-72cjogxz 2041 6 über über NNP cord-015369-72cjogxz 2041 7 44 44 CD cord-015369-72cjogxz 2041 8 Monate Monate NNP cord-015369-72cjogxz 2041 9 tumorfrei tumorfrei NNS cord-015369-72cjogxz 2041 10 , , , cord-015369-72cjogxz 2042 1 i -PRON- PRP cord-015369-72cjogxz 2042 2 m be VBP cord-015369-72cjogxz 2042 3 zweiten zweiten NNP cord-015369-72cjogxz 2042 4 Fall Fall NNP cord-015369-72cjogxz 2042 5 mit mit NNP cord-015369-72cjogxz 2043 1 bekannten bekannten NNP cord-015369-72cjogxz 2043 2 Lebermetastasen Lebermetastasen NNP cord-015369-72cjogxz 2043 3 bildeten bildeten NNP cord-015369-72cjogxz 2043 4 sich sich NNP cord-015369-72cjogxz 2043 5 zusätzlich zusätzlich NNP cord-015369-72cjogxz 2043 6 Lungen Lungen NNP cord-015369-72cjogxz 2043 7 - - HYPH cord-015369-72cjogxz 2043 8 und und NNP cord-015369-72cjogxz 2043 9 Knochenmetastasen Knochenmetastasen NNP cord-015369-72cjogxz 2043 10 , , , cord-015369-72cjogxz 2043 11 jedoch jedoch NNP cord-015369-72cjogxz 2043 12 kein kein NNP cord-015369-72cjogxz 2043 13 Lokalrezidiv Lokalrezidiv NNP cord-015369-72cjogxz 2043 14 mehr mehr NNP cord-015369-72cjogxz 2043 15 . . . cord-015369-72cjogxz 2044 1 Nach Nach NNP cord-015369-72cjogxz 2044 2 transanaler transanaler NNP cord-015369-72cjogxz 2045 1 Vollwandexzision vollwandexzision NN cord-015369-72cjogxz 2045 2 fand fand NN cord-015369-72cjogxz 2046 1 sich sich NNP cord-015369-72cjogxz 2046 2 bei bei NNP cord-015369-72cjogxz 2047 1 einem einem NNP cord-015369-72cjogxz 2047 2 Patienten Patienten NNP cord-015369-72cjogxz 2047 3 nach nach NNP cord-015369-72cjogxz 2047 4 3 3 CD cord-015369-72cjogxz 2048 1 Jahren Jahren NNP cord-015369-72cjogxz 2048 2 ein ein NNP cord-015369-72cjogxz 2048 3 Lokalrezidiv Lokalrezidiv NNP cord-015369-72cjogxz 2048 4 mit mit NNP cord-015369-72cjogxz 2048 5 Lebermetastasen Lebermetastasen NNP cord-015369-72cjogxz 2048 6 . . . cord-015369-72cjogxz 2049 1 Nach Nach NNP cord-015369-72cjogxz 2049 2 Radiochemotherapie Radiochemotherapie NNP cord-015369-72cjogxz 2049 3 und und XX cord-015369-72cjogxz 2050 1 kompletter kompletter NNP cord-015369-72cjogxz 2050 2 lokaler lokaler NNP cord-015369-72cjogxz 2050 3 Remission Remission NNP cord-015369-72cjogxz 2050 4 kam kam NNP cord-015369-72cjogxz 2050 5 es es XX cord-015369-72cjogxz 2050 6 zu zu NNP cord-015369-72cjogxz 2050 7 zusätzlichen zusätzlichen NNP cord-015369-72cjogxz 2050 8 Lungenfiliae Lungenfiliae NNP cord-015369-72cjogxz 2050 9 , , , cord-015369-72cjogxz 2050 10 jedoch jedoch NNP cord-015369-72cjogxz 2050 11 keinem keinem NNP cord-015369-72cjogxz 2050 12 Lokalrezidiv Lokalrezidiv NNP cord-015369-72cjogxz 2050 13 . . . cord-015369-72cjogxz 2051 1 Zwei Zwei NNP cord-015369-72cjogxz 2051 2 weitere weitere NNP cord-015369-72cjogxz 2051 3 Patienten Patienten NNP cord-015369-72cjogxz 2051 4 blieben blieben NNP cord-015369-72cjogxz 2051 5 trotz trotz NNP cord-015369-72cjogxz 2051 6 R1-Resektion R1-Resektion NNP cord-015369-72cjogxz 2051 7 des des NNP cord-015369-72cjogxz 2051 8 Primärtumors Primärtumors NNP cord-015369-72cjogxz 2051 9 nach nach NN cord-015369-72cjogxz 2051 10 neoadjuvanter neoadjuvanter NN cord-015369-72cjogxz 2051 11 Radiochemotherapie Radiochemotherapie NNP cord-015369-72cjogxz 2051 12 ohne ohne NNP cord-015369-72cjogxz 2051 13 Nachresektion Nachresektion NNP cord-015369-72cjogxz 2051 14 tumorfrei tumorfrei NN cord-015369-72cjogxz 2051 15 . . . cord-015369-72cjogxz 2052 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 2052 2 . . . cord-015369-72cjogxz 2053 1 In in IN cord-015369-72cjogxz 2053 2 selektiven selektiven NNP cord-015369-72cjogxz 2053 3 Fällen Fällen NNP cord-015369-72cjogxz 2053 4 von von NNP cord-015369-72cjogxz 2053 5 Rektumkarzinomen Rektumkarzinomen NNP cord-015369-72cjogxz 2053 6 und und IN cord-015369-72cjogxz 2053 7 Rezidivtumoren rezidivtumoren NN cord-015369-72cjogxz 2053 8 ist ist NN cord-015369-72cjogxz 2053 9 durch durch NNP cord-015369-72cjogxz 2053 10 Radiochemotherapie Radiochemotherapie NNP cord-015369-72cjogxz 2053 11 eine eine NNP cord-015369-72cjogxz 2053 12 Vollremission Vollremission NNP cord-015369-72cjogxz 2053 13 zu zu NNP cord-015369-72cjogxz 2053 14 erzielen erzielen NNP cord-015369-72cjogxz 2053 15 , , , cord-015369-72cjogxz 2053 16 die die VB cord-015369-72cjogxz 2053 17 langfristig langfristig NNP cord-015369-72cjogxz 2053 18 anhält anhält NNP cord-015369-72cjogxz 2053 19 und und NNP cord-015369-72cjogxz 2053 20 ein ein NNP cord-015369-72cjogxz 2053 21 abwartendes abwartendes NNP cord-015369-72cjogxz 2054 1 Verhalten Verhalten NNP cord-015369-72cjogxz 2054 2 unter unter JJ cord-015369-72cjogxz 2054 3 engmaschiger engmaschiger JJ cord-015369-72cjogxz 2054 4 Kontrolle Kontrolle NNP cord-015369-72cjogxz 2054 5 rechtfertigt rechtfertigt NNP cord-015369-72cjogxz 2054 6 . . . cord-015369-72cjogxz 2055 1 Neoadjuvante Neoadjuvante NNP cord-015369-72cjogxz 2055 2 und und XX cord-015369-72cjogxz 2056 1 adjuvante adjuvante NNP cord-015369-72cjogxz 2056 2 Therapie Therapie NNP cord-015369-72cjogxz 2056 3 des des FW cord-015369-72cjogxz 2056 4 Rektumkarzinoms Rektumkarzinoms NNP cord-015369-72cjogxz 2057 1 i i PRP cord-015369-72cjogxz 2058 1 m m NNP cord-015369-72cjogxz 2058 2 klinischen klinischen NNP cord-015369-72cjogxz 2059 1 Alltageine Alltageine NNP cord-015369-72cjogxz 2059 2 aktuelle aktuelle NN cord-015369-72cjogxz 2060 1 Analyse Analyse NNP cord-015369-72cjogxz 2060 2 des des NNP cord-015369-72cjogxz 2061 1 i -PRON- PRP cord-015369-72cjogxz 2061 2 m be VBP cord-015369-72cjogxz 2061 3 Tumorzentrum Tumorzentrum NNP cord-015369-72cjogxz 2061 4 erfassten erfassten NNP cord-015369-72cjogxz 2061 5 Patientengutes Patientengutes NNP cord-015369-72cjogxz 2061 6 K. K. NNP cord-015369-72cjogxz 2061 7 Dommisch Dommisch NNP cord-015369-72cjogxz 2061 8 , , , cord-015369-72cjogxz 2061 9 J. J. NNP cord-015369-72cjogxz 2061 10 Sauer Sauer NNP cord-015369-72cjogxz 2061 11 , , , cord-015369-72cjogxz 2061 12 K. K. NNP cord-015369-72cjogxz 2061 13 Sobolewski Sobolewski NNP cord-015369-72cjogxz 2061 14 Neoadjuvante Neoadjuvante NNP cord-015369-72cjogxz 2061 15 und und VBD cord-015369-72cjogxz 2061 16 adjuvante adjuvante NNP cord-015369-72cjogxz 2061 17 Therapieverfahren Therapieverfahren NNP cord-015369-72cjogxz 2061 18 beim beim NNP cord-015369-72cjogxz 2061 19 Rektumkarzinom Rektumkarzinom NNP cord-015369-72cjogxz 2061 20 sollen sollen NNP cord-015369-72cjogxz 2061 21 zur zur NNP cord-015369-72cjogxz 2061 22 Verbesserung Verbesserung NNP cord-015369-72cjogxz 2061 23 der der NNP cord-015369-72cjogxz 2061 24 lokalen lokalen NNP cord-015369-72cjogxz 2061 25 Tumorkontrolle Tumorkontrolle NNP cord-015369-72cjogxz 2061 26 und und NNP cord-015369-72cjogxz 2061 27 zur zur NNP cord-015369-72cjogxz 2061 28 Hemmung Hemmung NNP cord-015369-72cjogxz 2061 29 dissiminierter dissiminierter NNP cord-015369-72cjogxz 2061 30 Tumorzellen Tumorzellen NNP cord-015369-72cjogxz 2061 31 beitragen beitragen NNP cord-015369-72cjogxz 2061 32 . . . cord-015369-72cjogxz 2062 1 Diese Diese NNP cord-015369-72cjogxz 2062 2 Aussage Aussage NNP cord-015369-72cjogxz 2062 3 gilt gilt NN cord-015369-72cjogxz 2062 4 als als NN cord-015369-72cjogxz 2062 5 allgemein allgemein NNP cord-015369-72cjogxz 2062 6 akzeptiert akzeptiert NNP cord-015369-72cjogxz 2062 7 und und NNP cord-015369-72cjogxz 2062 8 wird wird NNP cord-015369-72cjogxz 2062 9 in in IN cord-015369-72cjogxz 2062 10 Form Form NNP cord-015369-72cjogxz 2062 11 der der NNP cord-015369-72cjogxz 2062 12 Therapieempfehlungen Therapieempfehlungen NNP cord-015369-72cjogxz 2062 13 vertreten vertreten NNP cord-015369-72cjogxz 2062 14 . . . cord-015369-72cjogxz 2063 1 Die die VB cord-015369-72cjogxz 2063 2 deutsche deutsche NNP cord-015369-72cjogxz 2063 3 Studie Studie NNP cord-015369-72cjogxz 2063 4 konnte konnte NNP cord-015369-72cjogxz 2063 5 in in IN cord-015369-72cjogxz 2063 6 einer einer NNP cord-015369-72cjogxz 2063 7 Phase-3-Studie Phase-3-Studie NNP cord-015369-72cjogxz 2063 8 eindeutig eindeutig NNP cord-015369-72cjogxz 2063 9 zeigen zeigen NNP cord-015369-72cjogxz 2063 10 , , , cord-015369-72cjogxz 2063 11 dass dass NNP cord-015369-72cjogxz 2063 12 der der NNP cord-015369-72cjogxz 2063 13 präoperativen präoperativen NNP cord-015369-72cjogxz 2064 1 Strahlentherapie Strahlentherapie NNP cord-015369-72cjogxz 2065 1 i i PRP cord-015369-72cjogxz 2066 1 m m LS cord-015369-72cjogxz 2067 1 Vergleich Vergleich NNP cord-015369-72cjogxz 2068 1 zur zur NNP cord-015369-72cjogxz 2068 2 postoperativen postoperativen NNP cord-015369-72cjogxz 2069 1 Strahlentherapie Strahlentherapie NNP cord-015369-72cjogxz 2069 2 der der NNP cord-015369-72cjogxz 2069 3 Vorzug Vorzug NNP cord-015369-72cjogxz 2069 4 gegeben gegeben NN cord-015369-72cjogxz 2069 5 werden werden NNP cord-015369-72cjogxz 2069 6 muss muss NNP cord-015369-72cjogxz 2069 7 , , , cord-015369-72cjogxz 2069 8 da da NNP cord-015369-72cjogxz 2069 9 sowohl sowohl NNP cord-015369-72cjogxz 2069 10 Kurzzeit Kurzzeit NNP cord-015369-72cjogxz 2069 11 - - HYPH cord-015369-72cjogxz 2069 12 als als NNP cord-015369-72cjogxz 2069 13 auch auch NNP cord-015369-72cjogxz 2069 14 Langzeittoxidität Langzeittoxidität NNP cord-015369-72cjogxz 2069 15 postoperativ postoperativ JJ cord-015369-72cjogxz 2069 16 signifikant signifikant NNP cord-015369-72cjogxz 2069 17 höher höher NNP cord-015369-72cjogxz 2069 18 waren waren NNP cord-015369-72cjogxz 2069 19 . . . cord-015369-72cjogxz 2070 1 Die die VB cord-015369-72cjogxz 2070 2 Analyse Analyse NNP cord-015369-72cjogxz 2070 3 des des FW cord-015369-72cjogxz 2071 1 i i PRP cord-015369-72cjogxz 2072 1 m m LS cord-015369-72cjogxz 2073 1 Tumorzentrum Tumorzentrum NNP cord-015369-72cjogxz 2073 2 Schwerin Schwerin NNP cord-015369-72cjogxz 2073 3 erfassten erfassten NNP cord-015369-72cjogxz 2073 4 Patientengutes Patientengutes NNP cord-015369-72cjogxz 2073 5 ( ( -LRB- cord-015369-72cjogxz 2073 6 636 636 CD cord-015369-72cjogxz 2073 7 Patienten Patienten NNP cord-015369-72cjogxz 2073 8 ) ) -RRB- cord-015369-72cjogxz 2073 9 zeigt zeigt NNP cord-015369-72cjogxz 2073 10 , , , cord-015369-72cjogxz 2073 11 dass dass NNP cord-015369-72cjogxz 2073 12 nur nur NNP cord-015369-72cjogxz 2074 1 zwischen zwischen NNP cord-015369-72cjogxz 2074 2 15 15 CD cord-015369-72cjogxz 2074 3 - - SYM cord-015369-72cjogxz 2074 4 33 33 CD cord-015369-72cjogxz 2074 5 % % NN cord-015369-72cjogxz 2074 6 der der NN cord-015369-72cjogxz 2074 7 betroffenen betroffenen NNP cord-015369-72cjogxz 2075 1 Patienten Patienten NNP cord-015369-72cjogxz 2076 1 i -PRON- PRP cord-015369-72cjogxz 2076 2 m be VBP cord-015369-72cjogxz 2076 3 Durchschnitt Durchschnitt NNP cord-015369-72cjogxz 2076 4 in in IN cord-015369-72cjogxz 2076 5 derartige derartige NNP cord-015369-72cjogxz 2076 6 multimodale multimodale NNP cord-015369-72cjogxz 2076 7 Therapiekonzepte Therapiekonzepte NNP cord-015369-72cjogxz 2076 8 gelangen gelangen NNP cord-015369-72cjogxz 2076 9 . . . cord-015369-72cjogxz 2077 1 Das Das NNP cord-015369-72cjogxz 2077 2 eigene eigene NNP cord-015369-72cjogxz 2077 3 Patientengut Patientengut NNP cord-015369-72cjogxz 2077 4 der der NNP cord-015369-72cjogxz 2077 5 letzten letzten NNP cord-015369-72cjogxz 2077 6 2 2 CD cord-015369-72cjogxz 2077 7 Jahre Jahre NNP cord-015369-72cjogxz 2078 1 umfasste umfasste NNP cord-015369-72cjogxz 2078 2 87 87 CD cord-015369-72cjogxz 2079 1 Patienten Patienten NNP cord-015369-72cjogxz 2079 2 . . . cord-015369-72cjogxz 2080 1 Davon Davon NNP cord-015369-72cjogxz 2080 2 hatten hatten VBD cord-015369-72cjogxz 2080 3 38 38 CD cord-015369-72cjogxz 2081 1 Patienten Patienten NNP cord-015369-72cjogxz 2082 1 ein ein NNP cord-015369-72cjogxz 2082 2 Rektumkarzinom Rektumkarzinom NNP cord-015369-72cjogxz 2083 1 i -PRON- PRP cord-015369-72cjogxz 2083 2 m be VBP cord-015369-72cjogxz 2083 3 unteren unteren NNP cord-015369-72cjogxz 2083 4 und und NNP cord-015369-72cjogxz 2083 5 mittleren mittleren NNP cord-015369-72cjogxz 2084 1 Drittel Drittel NNP cord-015369-72cjogxz 2084 2 i -PRON- PRP cord-015369-72cjogxz 2084 3 m be VBP cord-015369-72cjogxz 2084 4 UICC UICC NNP cord-015369-72cjogxz 2084 5 - - HYPH cord-015369-72cjogxz 2084 6 Stadium Stadium NNP cord-015369-72cjogxz 2084 7 II II NNP cord-015369-72cjogxz 2084 8 und und IN cord-015369-72cjogxz 2084 9 III III NNP cord-015369-72cjogxz 2084 10 . . . cord-015369-72cjogxz 2085 1 Letztlich Letztlich NNP cord-015369-72cjogxz 2085 2 erhielten erhielten NN cord-015369-72cjogxz 2085 3 17 17 CD cord-015369-72cjogxz 2086 1 Patienten Patienten NNP cord-015369-72cjogxz 2086 2 ein ein FW cord-015369-72cjogxz 2086 3 komplettes komplettes FW cord-015369-72cjogxz 2086 4 neoadjuvantes neoadjuvantes NNP cord-015369-72cjogxz 2086 5 The the DT cord-015369-72cjogxz 2086 6 - - HYPH cord-015369-72cjogxz 2086 7 rapieschema rapieschema NNP cord-015369-72cjogxz 2086 8 ( ( -LRB- cord-015369-72cjogxz 2086 9 ¼ ¼ CD cord-015369-72cjogxz 2086 10 47 47 CD cord-015369-72cjogxz 2086 11 % % NN cord-015369-72cjogxz 2086 12 ) ) -RRB- cord-015369-72cjogxz 2086 13 . . . cord-015369-72cjogxz 2087 1 Für Für NNP cord-015369-72cjogxz 2087 2 eine eine NNP cord-015369-72cjogxz 2087 3 adjuvante adjuvante JJ cord-015369-72cjogxz 2087 4 Therapie Therapie NNP cord-015369-72cjogxz 2087 5 kamen kamen NNP cord-015369-72cjogxz 2087 6 33 33 CD cord-015369-72cjogxz 2087 7 Patienten Patienten NNP cord-015369-72cjogxz 2087 8 in in IN cord-015369-72cjogxz 2087 9 Frage Frage NNP cord-015369-72cjogxz 2087 10 ( ( -LRB- cord-015369-72cjogxz 2087 11 16 16 CD cord-015369-72cjogxz 2087 12 mit mit NN cord-015369-72cjogxz 2087 13 falsch falsch JJ cord-015369-72cjogxz 2088 1 negativem negativem NNP cord-015369-72cjogxz 2088 2 Staying Staying NNP cord-015369-72cjogxz 2089 1 , , , cord-015369-72cjogxz 2089 2 6 6 CD cord-015369-72cjogxz 2089 3 Notfallpatienten Notfallpatienten NNP cord-015369-72cjogxz 2089 4 und und IN cord-015369-72cjogxz 2089 5 11 11 CD cord-015369-72cjogxz 2089 6 mit mit NNP cord-015369-72cjogxz 2089 7 einem einem NNP cord-015369-72cjogxz 2089 8 Karzinom Karzinom NNP cord-015369-72cjogxz 2090 1 i -PRON- PRP cord-015369-72cjogxz 2090 2 m be VBP cord-015369-72cjogxz 2090 3 oberen oberen NNP cord-015369-72cjogxz 2090 4 Drittel Drittel NNP cord-015369-72cjogxz 2090 5 ) ) -RRB- cord-015369-72cjogxz 2090 6 , , , cord-015369-72cjogxz 2090 7 eine eine NNP cord-015369-72cjogxz 2090 8 adjuvante adjuvante NNP cord-015369-72cjogxz 2090 9 Therapie Therapie NNP cord-015369-72cjogxz 2090 10 konnten konnten NNP cord-015369-72cjogxz 2090 11 aber aber NNP cord-015369-72cjogxz 2090 12 nur nur NNP cord-015369-72cjogxz 2090 13 20 20 CD cord-015369-72cjogxz 2090 14 Patienten Patienten NNP cord-015369-72cjogxz 2090 15 in in IN cord-015369-72cjogxz 2090 16 Anspruch Anspruch NNP cord-015369-72cjogxz 2090 17 nehmen nehmen NNP cord-015369-72cjogxz 2090 18 . . . cord-015369-72cjogxz 2091 1 Mit Mit NNP cord-015369-72cjogxz 2091 2 den den NNP cord-015369-72cjogxz 2091 3 Ursachen Ursachen NNP cord-015369-72cjogxz 2092 1 und und NNP cord-015369-72cjogxz 2093 1 Hintergründen Hintergründen NNP cord-015369-72cjogxz 2093 2 dieses dieses NN cord-015369-72cjogxz 2093 3 doch doch NN cord-015369-72cjogxz 2093 4 ernüchternden ernüchternden JJ cord-015369-72cjogxz 2093 5 Ergebnisses Ergebnisses NNP cord-015369-72cjogxz 2094 1 setzt setzt NNP cord-015369-72cjogxz 2094 2 sich sich NNP cord-015369-72cjogxz 2094 3 der der NNP cord-015369-72cjogxz 2094 4 vorliegende vorliegende NNP cord-015369-72cjogxz 2094 5 Beitrag Beitrag NNP cord-015369-72cjogxz 2094 6 auseinander auseinander NNP cord-015369-72cjogxz 2094 7 . . . cord-015369-72cjogxz 2095 1 Die die VB cord-015369-72cjogxz 2095 2 Entwicklungsdynamik Entwicklungsdynamik NNP cord-015369-72cjogxz 2095 3 in in IN cord-015369-72cjogxz 2095 4 der der NNP cord-015369-72cjogxz 2095 5 Anwendung Anwendung NNP cord-015369-72cjogxz 2095 6 dieser dieser NNP cord-015369-72cjogxz 2095 7 Therapiekonzepte Therapiekonzepte NNP cord-015369-72cjogxz 2095 8 innnerhalb innnerhalb NNP cord-015369-72cjogxz 2095 9 des des FW cord-015369-72cjogxz 2095 10 letzten letzten NNP cord-015369-72cjogxz 2095 11 Jahrzehntes Jahrzehntes NNP cord-015369-72cjogxz 2095 12 wird wird NNP cord-015369-72cjogxz 2095 13 differenziert differenziert NNP cord-015369-72cjogxz 2095 14 in in IN cord-015369-72cjogxz 2095 15 bezug bezug NNP cord-015369-72cjogxz 2095 16 auf auf NNP cord-015369-72cjogxz 2095 17 die die VBP cord-015369-72cjogxz 2095 18 eigene eigene NNP cord-015369-72cjogxz 2095 19 Klinik Klinik NNP cord-015369-72cjogxz 2096 1 und und NNP cord-015369-72cjogxz 2096 2 die die VB cord-015369-72cjogxz 2097 1 i -PRON- PRP cord-015369-72cjogxz 2097 2 m be VBP cord-015369-72cjogxz 2097 3 Tumorzentrum Tumorzentrum NNP cord-015369-72cjogxz 2097 4 erfassten erfassten NNP cord-015369-72cjogxz 2097 5 Kliniken Kliniken NNP cord-015369-72cjogxz 2097 6 von von NNP cord-015369-72cjogxz 2097 7 unterschiedlichen unterschiedlichen NN cord-015369-72cjogxz 2097 8 Versorgungsebenen Versorgungsebenen NNP cord-015369-72cjogxz 2097 9 dargestellt dargestellt NNP cord-015369-72cjogxz 2097 10 . . . cord-015369-72cjogxz 2098 1 Auch Auch NNP cord-015369-72cjogxz 2098 2 werden werden NNP cord-015369-72cjogxz 2098 3 die die VBP cord-015369-72cjogxz 2099 1 patientenseitig patientenseitig NNP cord-015369-72cjogxz 2099 2 vorhandenen vorhandenen NNP cord-015369-72cjogxz 2100 1 Gegebenheiten Gegebenheiten NNP cord-015369-72cjogxz 2100 2 hinsichtlich hinsichtlich NNP cord-015369-72cjogxz 2100 3 der der NNP cord-015369-72cjogxz 2100 4 Durchführbarkeit Durchführbarkeit NNP cord-015369-72cjogxz 2100 5 der der NNP cord-015369-72cjogxz 2101 1 diskutierten diskutierten NNP cord-015369-72cjogxz 2101 2 Therapieverfahren Therapieverfahren NNP cord-015369-72cjogxz 2101 3 angesprochen angesprochen NNP cord-015369-72cjogxz 2101 4 . . . cord-015369-72cjogxz 2102 1 Background background NN cord-015369-72cjogxz 2102 2 . . . cord-015369-72cjogxz 2103 1 Tetrahydrobiopterin Tetrahydrobiopterin NNP cord-015369-72cjogxz 2103 2 ( ( -LRB- cord-015369-72cjogxz 2103 3 BH4 BH4 NNP cord-015369-72cjogxz 2103 4 ) ) -RRB- cord-015369-72cjogxz 2103 5 is be VBZ cord-015369-72cjogxz 2103 6 an an DT cord-015369-72cjogxz 2103 7 essential essential JJ cord-015369-72cjogxz 2103 8 cofactor cofactor NN cord-015369-72cjogxz 2103 9 for for IN cord-015369-72cjogxz 2103 10 nitric nitric JJ cord-015369-72cjogxz 2103 11 oxide oxide NN cord-015369-72cjogxz 2103 12 synthases synthase NNS cord-015369-72cjogxz 2103 13 ( ( -LRB- cord-015369-72cjogxz 2103 14 NOS NOS NNP cord-015369-72cjogxz 2103 15 ) ) -RRB- cord-015369-72cjogxz 2103 16 and and CC cord-015369-72cjogxz 2103 17 thus thus RB cord-015369-72cjogxz 2103 18 a a DT cord-015369-72cjogxz 2103 19 critical critical JJ cord-015369-72cjogxz 2103 20 determinant determinant NN cord-015369-72cjogxz 2103 21 of of IN cord-015369-72cjogxz 2103 22 NO no DT cord-015369-72cjogxz 2103 23 production production NN cord-015369-72cjogxz 2103 24 . . . cord-015369-72cjogxz 2104 1 BH4 bh4 JJ cord-015369-72cjogxz 2104 2 depletion depletion NN cord-015369-72cjogxz 2104 3 during during IN cord-015369-72cjogxz 2104 4 cold cold JJ cord-015369-72cjogxz 2104 5 ischemia ischemia NN cord-015369-72cjogxz 2104 6 leads lead VBZ cord-015369-72cjogxz 2104 7 to to IN cord-015369-72cjogxz 2104 8 uncoupling uncoupling NN cord-015369-72cjogxz 2104 9 of of IN cord-015369-72cjogxz 2104 10 NOS NOS NNP cord-015369-72cjogxz 2104 11 and and CC cord-015369-72cjogxz 2104 12 contributes contribute VBZ cord-015369-72cjogxz 2104 13 to to IN cord-015369-72cjogxz 2104 14 reperfusion reperfusion NN cord-015369-72cjogxz 2104 15 injury injury NN cord-015369-72cjogxz 2104 16 ( ( -LRB- cord-015369-72cjogxz 2104 17 IRI IRI NNP cord-015369-72cjogxz 2104 18 ) ) -RRB- cord-015369-72cjogxz 2104 19 due due JJ cord-015369-72cjogxz 2104 20 to to IN cord-015369-72cjogxz 2104 21 increased increase VBN cord-015369-72cjogxz 2104 22 superoxide superoxide NN cord-015369-72cjogxz 2104 23 formation formation NN cord-015369-72cjogxz 2104 24 . . . cord-015369-72cjogxz 2105 1 The the DT cord-015369-72cjogxz 2105 2 role role NN cord-015369-72cjogxz 2105 3 of of IN cord-015369-72cjogxz 2105 4 BH4 BH4 NNP cord-015369-72cjogxz 2105 5 during during IN cord-015369-72cjogxz 2105 6 warm warm JJ cord-015369-72cjogxz 2105 7 ischemia ischemia NN cord-015369-72cjogxz 2105 8 is be VBZ cord-015369-72cjogxz 2105 9 still still RB cord-015369-72cjogxz 2105 10 largely largely RB cord-015369-72cjogxz 2105 11 unknown unknown JJ cord-015369-72cjogxz 2105 12 . . . cord-015369-72cjogxz 2106 1 Methods method NNS cord-015369-72cjogxz 2106 2 . . . cord-015369-72cjogxz 2107 1 Ischemic ischemic JJ cord-015369-72cjogxz 2107 2 renal renal JJ cord-015369-72cjogxz 2107 3 injury injury NN cord-015369-72cjogxz 2107 4 was be VBD cord-015369-72cjogxz 2107 5 induced induce VBN cord-015369-72cjogxz 2107 6 by by IN cord-015369-72cjogxz 2107 7 clamping clamp VBG cord-015369-72cjogxz 2107 8 the the DT cord-015369-72cjogxz 2107 9 left left JJ cord-015369-72cjogxz 2107 10 renal renal JJ cord-015369-72cjogxz 2107 11 artery artery NN cord-015369-72cjogxz 2107 12 for for IN cord-015369-72cjogxz 2107 13 45 45 CD cord-015369-72cjogxz 2107 14 min min NN cord-015369-72cjogxz 2107 15 in in IN cord-015369-72cjogxz 2107 16 male male JJ cord-015369-72cjogxz 2107 17 Lewis Lewis NNP cord-015369-72cjogxz 2107 18 rats rat NNS cord-015369-72cjogxz 2107 19 immediately immediately RB cord-015369-72cjogxz 2107 20 after after IN cord-015369-72cjogxz 2107 21 right right JJ cord-015369-72cjogxz 2107 22 - - HYPH cord-015369-72cjogxz 2107 23 side side NN cord-015369-72cjogxz 2107 24 nephrectomy nephrectomy NN cord-015369-72cjogxz 2107 25 . . . cord-015369-72cjogxz 2108 1 Reperfusion reperfusion NN cord-015369-72cjogxz 2108 2 was be VBD cord-015369-72cjogxz 2108 3 studied study VBN cord-015369-72cjogxz 2108 4 at at IN cord-015369-72cjogxz 2108 5 R0 R0 NNP cord-015369-72cjogxz 2108 6 ( ( -LRB- cord-015369-72cjogxz 2108 7 no no DT cord-015369-72cjogxz 2108 8 reperfusion reperfusion NN cord-015369-72cjogxz 2108 9 ) ) -RRB- cord-015369-72cjogxz 2108 10 , , , cord-015369-72cjogxz 2108 11 15 15 CD cord-015369-72cjogxz 2108 12 min(R1 min(R1 NNP cord-015369-72cjogxz 2108 13 ) ) -RRB- cord-015369-72cjogxz 2108 14 , , , cord-015369-72cjogxz 2108 15 2 2 CD cord-015369-72cjogxz 2108 16 h(R2 h(r2 ADD cord-015369-72cjogxz 2108 17 ) ) -RRB- cord-015369-72cjogxz 2108 18 and and CC cord-015369-72cjogxz 2108 19 7days(R3 7days(r3 CD cord-015369-72cjogxz 2108 20 ) ) -RRB- cord-015369-72cjogxz 2108 21 . . . cord-015369-72cjogxz 2109 1 Animals animal NNS cord-015369-72cjogxz 2109 2 received receive VBD cord-015369-72cjogxz 2109 3 either either CC cord-015369-72cjogxz 2109 4 BH4 bh4 JJ cord-015369-72cjogxz 2109 5 ( ( -LRB- cord-015369-72cjogxz 2109 6 20 20 CD cord-015369-72cjogxz 2109 7 mg mg NNP cord-015369-72cjogxz 2109 8 / / SYM cord-015369-72cjogxz 2109 9 kg kg NNP cord-015369-72cjogxz 2109 10 / / SYM cord-015369-72cjogxz 2109 11 BW BW NNP cord-015369-72cjogxz 2109 12 ) ) -RRB- cord-015369-72cjogxz 2109 13 prior prior RB cord-015369-72cjogxz 2109 14 to to IN cord-015369-72cjogxz 2109 15 reperfusion reperfusion NN cord-015369-72cjogxz 2109 16 ( ( -LRB- cord-015369-72cjogxz 2109 17 GroupI groupi RB cord-015369-72cjogxz 2109 18 ) ) -RRB- cord-015369-72cjogxz 2109 19 or or CC cord-015369-72cjogxz 2109 20 saline(GroupII saline(GroupII NNP cord-015369-72cjogxz 2109 21 ) ) -RRB- cord-015369-72cjogxz 2109 22 . . . cord-015369-72cjogxz 2110 1 Sham Sham NNP cord-015369-72cjogxz 2110 2 operated operate VBD cord-015369-72cjogxz 2110 3 animals animal NNS cord-015369-72cjogxz 2110 4 served serve VBD cord-015369-72cjogxz 2110 5 as as IN cord-015369-72cjogxz 2110 6 controls(GroupIII controls(groupiii CD cord-015369-72cjogxz 2110 7 ) ) -RRB- cord-015369-72cjogxz 2110 8 . . . cord-015369-72cjogxz 2111 1 Renal renal JJ cord-015369-72cjogxz 2111 2 function function NN cord-015369-72cjogxz 2111 3 was be VBD cord-015369-72cjogxz 2111 4 determined determine VBN cord-015369-72cjogxz 2111 5 by by IN cord-015369-72cjogxz 2111 6 plasma plasma NN cord-015369-72cjogxz 2111 7 creatinine creatinine NN cord-015369-72cjogxz 2111 8 / / SYM cord-015369-72cjogxz 2111 9 urea urea NN cord-015369-72cjogxz 2111 10 . . . cord-015369-72cjogxz 2112 1 BH4 bh4 JJ cord-015369-72cjogxz 2112 2 tissue tissue NN cord-015369-72cjogxz 2112 3 levels level NNS cord-015369-72cjogxz 2112 4 were be VBD cord-015369-72cjogxz 2112 5 assessed assess VBN cord-015369-72cjogxz 2112 6 by by IN cord-015369-72cjogxz 2112 7 HPLC HPLC NNP cord-015369-72cjogxz 2112 8 . . . cord-015369-72cjogxz 2113 1 Morphologic morphologic JJ cord-015369-72cjogxz 2113 2 changes change NNS cord-015369-72cjogxz 2113 3 were be VBD cord-015369-72cjogxz 2113 4 quantified quantify VBN cord-015369-72cjogxz 2113 5 by by IN cord-015369-72cjogxz 2113 6 H&E H&E NNP cord-015369-72cjogxz 2113 7 histology histology NN cord-015369-72cjogxz 2113 8 . . . cord-015369-72cjogxz 2114 1 Peroxynitrite peroxynitrite JJ cord-015369-72cjogxz 2114 2 formation formation NN cord-015369-72cjogxz 2114 3 was be VBD cord-015369-72cjogxz 2114 4 assessed assess VBN cord-015369-72cjogxz 2114 5 by by IN cord-015369-72cjogxz 2114 6 nitrotyrosine nitrotyrosine NN cord-015369-72cjogxz 2114 7 - - HYPH cord-015369-72cjogxz 2114 8 immunostaining immunostaine VBG cord-015369-72cjogxz 2114 9 , , , cord-015369-72cjogxz 2114 10 kidney kidney NN cord-015369-72cjogxz 2114 11 microcirculation microcirculation NN cord-015369-72cjogxz 2114 12 was be VBD cord-015369-72cjogxz 2114 13 analyzed analyze VBN cord-015369-72cjogxz 2114 14 by by IN cord-015369-72cjogxz 2114 15 means mean NNS cord-015369-72cjogxz 2114 16 of of IN cord-015369-72cjogxz 2114 17 functional functional JJ cord-015369-72cjogxz 2114 18 capillary capillary JJ cord-015369-72cjogxz 2114 19 density density NN cord-015369-72cjogxz 2114 20 and and CC cord-015369-72cjogxz 2114 21 capillary capillary JJ cord-015369-72cjogxz 2114 22 diameters diameter NNS cord-015369-72cjogxz 2114 23 uing ue VBG cord-015369-72cjogxz 2114 24 intravital intravital JJ cord-015369-72cjogxz 2114 25 microscopy microscopy NNP cord-015369-72cjogxz 2114 26 . . . cord-015369-72cjogxz 2115 1 Results result NNS cord-015369-72cjogxz 2115 2 . . . cord-015369-72cjogxz 2116 1 BH4 bh4 JJ cord-015369-72cjogxz 2116 2 tissue tissue NN cord-015369-72cjogxz 2116 3 levels level NNS cord-015369-72cjogxz 2116 4 significantly significantly RB cord-015369-72cjogxz 2116 5 decreased decrease VBD cord-015369-72cjogxz 2116 6 after after IN cord-015369-72cjogxz 2116 7 45 45 CD cord-015369-72cjogxz 2116 8 min min NN cord-015369-72cjogxz 2116 9 of of IN cord-015369-72cjogxz 2116 10 warm warm JJ cord-015369-72cjogxz 2116 11 ischemia ischemia NN cord-015369-72cjogxz 2116 12 ( ( -LRB- cord-015369-72cjogxz 2116 13 p p NN cord-015369-72cjogxz 2116 14 < < XX cord-015369-72cjogxz 2116 15 0.05 0.05 CD cord-015369-72cjogxz 2116 16 ) ) -RRB- cord-015369-72cjogxz 2116 17 up up IN cord-015369-72cjogxz 2116 18 to to TO cord-015369-72cjogxz 2116 19 two two CD cord-015369-72cjogxz 2116 20 days(R1,R2 days(r1,r2 JJ cord-015369-72cjogxz 2116 21 ) ) -RRB- cord-015369-72cjogxz 2116 22 when when WRB cord-015369-72cjogxz 2116 23 compared compare VBN cord-015369-72cjogxz 2116 24 to to IN cord-015369-72cjogxz 2116 25 non non JJ cord-015369-72cjogxz 2116 26 - - JJ cord-015369-72cjogxz 2116 27 ischemic ischemic JJ cord-015369-72cjogxz 2116 28 controls control NNS cord-015369-72cjogxz 2116 29 . . . cord-015369-72cjogxz 2117 1 Additional additional JJ cord-015369-72cjogxz 2117 2 BH4 bh4 JJ cord-015369-72cjogxz 2117 3 treatment treatment NN cord-015369-72cjogxz 2117 4 prior prior RB cord-015369-72cjogxz 2117 5 to to IN cord-015369-72cjogxz 2117 6 ischemia ischemia NN cord-015369-72cjogxz 2117 7 significantly significantly RB cord-015369-72cjogxz 2117 8 improved improve VBD cord-015369-72cjogxz 2117 9 renal renal JJ cord-015369-72cjogxz 2117 10 function function NN cord-015369-72cjogxz 2117 11 at at IN cord-015369-72cjogxz 2117 12 all all DT cord-015369-72cjogxz 2117 13 time time NN cord-015369-72cjogxz 2117 14 points point NNS cord-015369-72cjogxz 2117 15 studied study VBD cord-015369-72cjogxz 2117 16 following follow VBG cord-015369-72cjogxz 2117 17 reperfusion reperfusion NN cord-015369-72cjogxz 2117 18 ( ( -LRB- cord-015369-72cjogxz 2117 19 all all DT cord-015369-72cjogxz 2117 20 p p NN cord-015369-72cjogxz 2117 21 < < XX cord-015369-72cjogxz 2117 22 0.001 0.001 CD cord-015369-72cjogxz 2117 23 ) ) -RRB- cord-015369-72cjogxz 2117 24 . . . cord-015369-72cjogxz 2118 1 Furthermore furthermore RB cord-015369-72cjogxz 2118 2 , , , cord-015369-72cjogxz 2118 3 BH4 BH4 NNP cord-015369-72cjogxz 2118 4 reduced reduce VBN cord-015369-72cjogxz 2118 5 ischemia ischemia NN cord-015369-72cjogxz 2118 6 induced induce VBD cord-015369-72cjogxz 2118 7 histologic histologic JJ cord-015369-72cjogxz 2118 8 damage damage NN cord-015369-72cjogxz 2118 9 ( ( -LRB- cord-015369-72cjogxz 2118 10 increased increase VBN cord-015369-72cjogxz 2118 11 inflammation inflammation NN cord-015369-72cjogxz 2118 12 , , , cord-015369-72cjogxz 2118 13 interstitial interstitial JJ cord-015369-72cjogxz 2118 14 edema edema NN cord-015369-72cjogxz 2118 15 , , , cord-015369-72cjogxz 2118 16 hemorrhage hemorrhage NN cord-015369-72cjogxz 2118 17 , , , cord-015369-72cjogxz 2118 18 tubular tubular JJ cord-015369-72cjogxz 2118 19 atrophy atrophy NN cord-015369-72cjogxz 2118 20 and and CC cord-015369-72cjogxz 2118 21 focal focal JJ cord-015369-72cjogxz 2118 22 areas area NNS cord-015369-72cjogxz 2118 23 of of IN cord-015369-72cjogxz 2118 24 necrosis necrosis NN cord-015369-72cjogxz 2118 25 ) ) -RRB- cord-015369-72cjogxz 2118 26 and and CC cord-015369-72cjogxz 2118 27 diminished diminish VBD cord-015369-72cjogxz 2118 28 peroxynitrite peroxynitrite JJ cord-015369-72cjogxz 2118 29 formation formation NN cord-015369-72cjogxz 2118 30 and and CC cord-015369-72cjogxz 2118 31 hence hence RB cord-015369-72cjogxz 2118 32 nitrotyrosine nitrotyrosine NNP cord-015369-72cjogxz 2118 33 staining(R1-R3).Subsequently staining(r1-r3).subsequently RB cord-015369-72cjogxz 2118 34 , , , cord-015369-72cjogxz 2118 35 microcirculatory microcirculatory NNP cord-015369-72cjogxz 2118 36 changes change NNS cord-015369-72cjogxz 2118 37 correlated correlate VBN cord-015369-72cjogxz 2118 38 with with IN cord-015369-72cjogxz 2118 39 kidney kidney NN cord-015369-72cjogxz 2118 40 peroxynitrite peroxynitrite JJ cord-015369-72cjogxz 2118 41 generation generation NN cord-015369-72cjogxz 2118 42 , , , cord-015369-72cjogxz 2118 43 and and CC cord-015369-72cjogxz 2118 44 improved improve VBD cord-015369-72cjogxz 2118 45 considerably considerably RB cord-015369-72cjogxz 2118 46 through through IN cord-015369-72cjogxz 2118 47 BH4 bh4 JJ cord-015369-72cjogxz 2118 48 treatment treatment NN cord-015369-72cjogxz 2118 49 . . . cord-015369-72cjogxz 2119 1 Conclusions conclusion NNS cord-015369-72cjogxz 2119 2 . . . cord-015369-72cjogxz 2120 1 BH4 bh4 JJ cord-015369-72cjogxz 2120 2 treatment treatment NN cord-015369-72cjogxz 2120 3 significantly significantly RB cord-015369-72cjogxz 2120 4 improves improve VBZ cord-015369-72cjogxz 2120 5 post post JJ cord-015369-72cjogxz 2120 6 - - JJ cord-015369-72cjogxz 2120 7 ischemic ischemic JJ cord-015369-72cjogxz 2120 8 renal renal JJ cord-015369-72cjogxz 2120 9 function function NN cord-015369-72cjogxz 2120 10 as as RB cord-015369-72cjogxz 2120 11 well well RB cord-015369-72cjogxz 2120 12 as as IN cord-015369-72cjogxz 2120 13 histologic histologic JJ cord-015369-72cjogxz 2120 14 and and CC cord-015369-72cjogxz 2120 15 microcirculatory microcirculatory JJ cord-015369-72cjogxz 2120 16 function function NN cord-015369-72cjogxz 2120 17 and and CC cord-015369-72cjogxz 2120 18 might may MD cord-015369-72cjogxz 2120 19 be be VB cord-015369-72cjogxz 2120 20 a a DT cord-015369-72cjogxz 2120 21 promising promising JJ cord-015369-72cjogxz 2120 22 novel novel JJ cord-015369-72cjogxz 2120 23 therapeutic therapeutic JJ cord-015369-72cjogxz 2120 24 strategy strategy NN cord-015369-72cjogxz 2120 25 in in IN cord-015369-72cjogxz 2120 26 attenuating attenuate VBG cord-015369-72cjogxz 2120 27 IRI IRI NNP cord-015369-72cjogxz 2120 28 . . . cord-015369-72cjogxz 2121 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 2121 2 . . . cord-015369-72cjogxz 2122 1 Bei Bei NNP cord-015369-72cjogxz 2122 2 der der NNP cord-015369-72cjogxz 2122 3 Behandlung Behandlung NNP cord-015369-72cjogxz 2122 4 einer einer NNP cord-015369-72cjogxz 2122 5 peripheren peripheren NN cord-015369-72cjogxz 2122 6 traumatischen traumatischen NNP cord-015369-72cjogxz 2122 7 Nervendurchtrennung Nervendurchtrennung NNP cord-015369-72cjogxz 2122 8 konnte konnte NNP cord-015369-72cjogxz 2122 9 bisher bisher NNP cord-015369-72cjogxz 2122 10 trotz trotz NNP cord-015369-72cjogxz 2122 11 Anwendung Anwendung NNP cord-015369-72cjogxz 2122 12 modernster modernster NN cord-015369-72cjogxz 2122 13 Techniken Techniken NNP cord-015369-72cjogxz 2123 1 keine keine NNP cord-015369-72cjogxz 2123 2 zufriedenstellende zufriedenstellende NNP cord-015369-72cjogxz 2123 3 funktionelle funktionelle NNP cord-015369-72cjogxz 2124 1 Regeneration regeneration NN cord-015369-72cjogxz 2124 2 erzielt erzielt NNS cord-015369-72cjogxz 2124 3 werden werden NNP cord-015369-72cjogxz 2124 4 . . . cord-015369-72cjogxz 2125 1 Die Die NNP cord-015369-72cjogxz 2125 2 verzögerte verzögerte NNP cord-015369-72cjogxz 2126 1 Nervenregeneration Nervenregeneration NNP cord-015369-72cjogxz 2127 1 und und NNP cord-015369-72cjogxz 2127 2 die die VB cord-015369-72cjogxz 2128 1 daraus daraus NNP cord-015369-72cjogxz 2128 2 folgende folgende NNP cord-015369-72cjogxz 2128 3 verlangsamte verlangsamte NN cord-015369-72cjogxz 2128 4 Signalüberleitung Signalüberleitung NNP cord-015369-72cjogxz 2128 5 stellen stellen NNP cord-015369-72cjogxz 2129 1 eine eine NNP cord-015369-72cjogxz 2129 2 erhebliche erhebliche NNP cord-015369-72cjogxz 2129 3 Einschränkung Einschränkung NNP cord-015369-72cjogxz 2129 4 der der NNP cord-015369-72cjogxz 2129 5 Muskelfunktion Muskelfunktion NNP cord-015369-72cjogxz 2129 6 am be VBP cord-015369-72cjogxz 2129 7 Endversorgungsgebiet Endversorgungsgebiet NNP cord-015369-72cjogxz 2129 8 der der NNP cord-015369-72cjogxz 2129 9 betroffenen betroffenen NNP cord-015369-72cjogxz 2129 10 Nerven Nerven NNP cord-015369-72cjogxz 2129 11 dar dar NNP cord-015369-72cjogxz 2129 12 . . . cord-015369-72cjogxz 2130 1 Ziel Ziel NNP cord-015369-72cjogxz 2130 2 der der NNP cord-015369-72cjogxz 2130 3 Studie Studie NNP cord-015369-72cjogxz 2130 4 ist ist NNP cord-015369-72cjogxz 2130 5 es es NN cord-015369-72cjogxz 2130 6 , , , cord-015369-72cjogxz 2130 7 ein ein NNP cord-015369-72cjogxz 2130 8 neues neues NNP cord-015369-72cjogxz 2131 1 Nervenkoaptationssystem Nervenkoaptationssystem NNP cord-015369-72cjogxz 2132 1 unter unter JJ cord-015369-72cjogxz 2133 1 Verwendung Verwendung NNP cord-015369-72cjogxz 2133 2 einer einer NNP cord-015369-72cjogxz 2134 1 neuartigen neuartigen NNP cord-015369-72cjogxz 2134 2 künstlichen künstlichen NNP cord-015369-72cjogxz 2134 3 Prothese Prothese NNP cord-015369-72cjogxz 2134 4 mit mit NNP cord-015369-72cjogxz 2134 5 der der NNP cord-015369-72cjogxz 2135 1 i i PRP cord-015369-72cjogxz 2136 1 m m NNP cord-015369-72cjogxz 2136 2 klinischen klinischen NNP cord-015369-72cjogxz 2136 3 Alltag Alltag NNP cord-015369-72cjogxz 2136 4 verwendeten verwendeten NN cord-015369-72cjogxz 2136 5 klassischen klassischen NNP cord-015369-72cjogxz 2136 6 Nahtkoaptation Nahtkoaptation NNP cord-015369-72cjogxz 2136 7 zu zu NNP cord-015369-72cjogxz 2136 8 vergleichen vergleichen NNP cord-015369-72cjogxz 2136 9 . . . cord-015369-72cjogxz 2137 1 Neben Neben NNP cord-015369-72cjogxz 2137 2 der der NNP cord-015369-72cjogxz 2137 3 Zeit Zeit NNP cord-015369-72cjogxz 2137 4 und und IN cord-015369-72cjogxz 2137 5 Grad grad NN cord-015369-72cjogxz 2137 6 der der NNP cord-015369-72cjogxz 2137 7 Nervenregeneration Nervenregeneration NNP cord-015369-72cjogxz 2137 8 wird wird NNP cord-015369-72cjogxz 2137 9 auch auch JJ cord-015369-72cjogxz 2137 10 der der NN cord-015369-72cjogxz 2137 11 Einfluss Einfluss NNP cord-015369-72cjogxz 2137 12 der der NN cord-015369-72cjogxz 2137 13 Elektrostimulation elektrostimulation NN cord-015369-72cjogxz 2137 14 getestet getestet NN cord-015369-72cjogxz 2137 15 . . . cord-015369-72cjogxz 2138 1 Methodik Methodik NNP cord-015369-72cjogxz 2138 2 . . . cord-015369-72cjogxz 2139 1 Es Es NNP cord-015369-72cjogxz 2139 2 wurde wurde VBD cord-015369-72cjogxz 2139 3 an an DT cord-015369-72cjogxz 2139 4 14 14 CD cord-015369-72cjogxz 2139 5 weibliche weibliche NN cord-015369-72cjogxz 2139 6 Göttinger Göttinger NNP cord-015369-72cjogxz 2139 7 Minipigs Minipigs NNP cord-015369-72cjogxz 2139 8 mit mit NNP cord-015369-72cjogxz 2139 9 einem einem NNP cord-015369-72cjogxz 2139 10 Durchschnittsgewicht Durchschnittsgewicht NNP cord-015369-72cjogxz 2139 11 von von NNP cord-015369-72cjogxz 2139 12 ca ca NNP cord-015369-72cjogxz 2139 13 . . . cord-015369-72cjogxz 2140 1 35 35 CD cord-015369-72cjogxz 2140 2 - - SYM cord-015369-72cjogxz 2140 3 40 40 CD cord-015369-72cjogxz 2140 4 kg kg NNS cord-015369-72cjogxz 2140 5 der der NN cord-015369-72cjogxz 2140 6 Nervus Nervus NNP cord-015369-72cjogxz 2140 7 Ischiadicus Ischiadicus NNP cord-015369-72cjogxz 2140 8 durchtrennt durchtrennt NN cord-015369-72cjogxz 2140 9 . . . cord-015369-72cjogxz 2141 1 Während Während NNP cord-015369-72cjogxz 2141 2 die die VBP cord-015369-72cjogxz 2141 3 Tiere Tiere NNP cord-015369-72cjogxz 2141 4 in in IN cord-015369-72cjogxz 2141 5 der der NNP cord-015369-72cjogxz 2141 6 Gruppe Gruppe NNP cord-015369-72cjogxz 2141 7 I -PRON- PRP cord-015369-72cjogxz 2141 8 mittels mittels VBP cord-015369-72cjogxz 2141 9 mikrochirurgischer mikrochirurgischer NNP cord-015369-72cjogxz 2141 10 Koaptationsnaht Koaptationsnaht NNP cord-015369-72cjogxz 2141 11 versorgt versorgt NN cord-015369-72cjogxz 2141 12 wurden wurden NNP cord-015369-72cjogxz 2141 13 , , , cord-015369-72cjogxz 2141 14 wurden wurden NNP cord-015369-72cjogxz 2141 15 die die VBP cord-015369-72cjogxz 2141 16 Tiere Tiere NNP cord-015369-72cjogxz 2141 17 der der NNP cord-015369-72cjogxz 2141 18 Gruppe Gruppe NNP cord-015369-72cjogxz 2141 19 II II NNP cord-015369-72cjogxz 2141 20 mit mit NNP cord-015369-72cjogxz 2141 21 der der NNP cord-015369-72cjogxz 2141 22 neuartigen neuartigen NNP cord-015369-72cjogxz 2141 23 Nervenprothese Nervenprothese NNP cord-015369-72cjogxz 2141 24 behandelt behandelt NNP cord-015369-72cjogxz 2141 25 . . . cord-015369-72cjogxz 2142 1 Die die VB cord-015369-72cjogxz 2142 2 Hälfte Hälfte NNP cord-015369-72cjogxz 2142 3 der der NNP cord-015369-72cjogxz 2142 4 Tiere Tiere NNP cord-015369-72cjogxz 2142 5 in in IN cord-015369-72cjogxz 2142 6 jeder jeder NNP cord-015369-72cjogxz 2142 7 Gruppe Gruppe NNP cord-015369-72cjogxz 2142 8 wurde wurde VBD cord-015369-72cjogxz 2142 9 eine eine NNP cord-015369-72cjogxz 2142 10 postoperativen postoperativen NNP cord-015369-72cjogxz 2142 11 Nervenstimulation Nervenstimulation NNP cord-015369-72cjogxz 2142 12 zugefü zugefü HYPH cord-015369-72cjogxz 2142 13 hrt hrt NNP cord-015369-72cjogxz 2142 14 . . . cord-015369-72cjogxz 2143 1 Das Das NNP cord-015369-72cjogxz 2143 2 postoperative postoperative JJ cord-015369-72cjogxz 2143 3 Kontroll Kontroll NNP cord-015369-72cjogxz 2143 4 - - HYPH cord-015369-72cjogxz 2143 5 und und NNP cord-015369-72cjogxz 2144 1 Stimulationsschema Stimulationsschema NNP cord-015369-72cjogxz 2144 2 beträgt beträgt NNP cord-015369-72cjogxz 2144 3 9 9 CD cord-015369-72cjogxz 2144 4 Monate Monate NNP cord-015369-72cjogxz 2144 5 , , , cord-015369-72cjogxz 2145 1 in in IN cord-015369-72cjogxz 2145 2 denen denen NNP cord-015369-72cjogxz 2145 3 die die NNP cord-015369-72cjogxz 2145 4 Aussprossung Aussprossung NNP cord-015369-72cjogxz 2145 5 der der NNP cord-015369-72cjogxz 2145 6 Axone Axone NNP cord-015369-72cjogxz 2145 7 in in IN cord-015369-72cjogxz 2145 8 monatlichen monatlichen NNP cord-015369-72cjogxz 2145 9 Abständen Abständen NNP cord-015369-72cjogxz 2145 10 evaluiert evaluiert NNP cord-015369-72cjogxz 2145 11 wird wird NNP cord-015369-72cjogxz 2145 12 . . . cord-015369-72cjogxz 2146 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2146 2 . . . cord-015369-72cjogxz 2147 1 Nach Nach NNP cord-015369-72cjogxz 2147 2 den den NNP cord-015369-72cjogxz 2148 1 vorliegenden vorliegenden NNP cord-015369-72cjogxz 2148 2 ersten ersten NNP cord-015369-72cjogxz 2148 3 Daten Daten NNP cord-015369-72cjogxz 2148 4 konnten konnten NNP cord-015369-72cjogxz 2148 5 wir wir NNP cord-015369-72cjogxz 2148 6 feststellen feststellen NNP cord-015369-72cjogxz 2148 7 , , , cord-015369-72cjogxz 2149 1 dass dass NNP cord-015369-72cjogxz 2149 2 mit mit NNP cord-015369-72cjogxz 2149 3 der der NNP cord-015369-72cjogxz 2149 4 Nervenprothese Nervenprothese NNP cord-015369-72cjogxz 2149 5 ähnlich ähnlich NNP cord-015369-72cjogxz 2150 1 gute gute NNP cord-015369-72cjogxz 2150 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2150 3 erzielbar erzielbar NN cord-015369-72cjogxz 2150 4 sind sind NNP cord-015369-72cjogxz 2150 5 , , , cord-015369-72cjogxz 2150 6 ohne ohne NNP cord-015369-72cjogxz 2150 7 dabei dabei NNP cord-015369-72cjogxz 2150 8 sich sich NNP cord-015369-72cjogxz 2150 9 einer einer NNP cord-015369-72cjogxz 2150 10 relativ relativ NNP cord-015369-72cjogxz 2150 11 aufwendigen aufwendigen NNP cord-015369-72cjogxz 2151 1 mikrochirurgischen mikrochirurgischen NNP cord-015369-72cjogxz 2151 2 Nahttechnik Nahttechnik NNP cord-015369-72cjogxz 2151 3 bedienen bedienen NNP cord-015369-72cjogxz 2151 4 zu zu NNP cord-015369-72cjogxz 2151 5 müssen müssen NNP cord-015369-72cjogxz 2151 6 , , , cord-015369-72cjogxz 2151 7 und und IN cord-015369-72cjogxz 2151 8 in in IN cord-015369-72cjogxz 2151 9 Zukunft Zukunft NNP cord-015369-72cjogxz 2151 10 dadurch dadurch NNP cord-015369-72cjogxz 2151 11 auch auch NNP cord-015369-72cjogxz 2151 12 kein kein NNP cord-015369-72cjogxz 2152 1 spezielles spezielles NNP cord-015369-72cjogxz 2152 2 Zentrum Zentrum NNP cord-015369-72cjogxz 2152 3 für für IN cord-015369-72cjogxz 2152 4 mikrochirurgische mikrochirurgische NNP cord-015369-72cjogxz 2152 5 Operationen Operationen NNP cord-015369-72cjogxz 2152 6 aufgesucht aufgesucht NNP cord-015369-72cjogxz 2152 7 werden werden NNP cord-015369-72cjogxz 2152 8 muss muss NNP cord-015369-72cjogxz 2152 9 , , , cord-015369-72cjogxz 2152 10 sonder sonder NNP cord-015369-72cjogxz 2152 11 in in IN cord-015369-72cjogxz 2152 12 jedem jedem NNP cord-015369-72cjogxz 2152 13 chirurgisch chirurgisch FW cord-015369-72cjogxz 2152 14 tätigem tätigem NNP cord-015369-72cjogxz 2153 1 Krankenhaus Krankenhaus NNP cord-015369-72cjogxz 2153 2 diese diese NNP cord-015369-72cjogxz 2154 1 Prothese Prothese NNP cord-015369-72cjogxz 2154 2 eingesetzt eingesetzt VBD cord-015369-72cjogxz 2154 3 werden werden NNP cord-015369-72cjogxz 2154 4 kann kann NNP cord-015369-72cjogxz 2154 5 . . . cord-015369-72cjogxz 2155 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 2155 2 . . . cord-015369-72cjogxz 2156 1 Falls Falls NNP cord-015369-72cjogxz 2156 2 die die VB cord-015369-72cjogxz 2157 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2157 2 der der NNP cord-015369-72cjogxz 2157 3 Studie Studie NNP cord-015369-72cjogxz 2157 4 die die VBP cord-015369-72cjogxz 2157 5 vorläufigen vorläufigen NN cord-015369-72cjogxz 2157 6 Resultate Resultate NNP cord-015369-72cjogxz 2157 7 bestätigen bestätigen NNP cord-015369-72cjogxz 2157 8 sollten sollten NNP cord-015369-72cjogxz 2157 9 , , , cord-015369-72cjogxz 2157 10 wäre wäre NNP cord-015369-72cjogxz 2158 1 die die VB cord-015369-72cjogxz 2159 1 Implantation Implantation NNP cord-015369-72cjogxz 2159 2 dieser dieser NNP cord-015369-72cjogxz 2160 1 Nervenprothese Nervenprothese NNP cord-015369-72cjogxz 2161 1 eine eine NNP cord-015369-72cjogxz 2161 2 neue neue NNP cord-015369-72cjogxz 2161 3 und und NNP cord-015369-72cjogxz 2161 4 von von NNP cord-015369-72cjogxz 2161 5 Jederfrau Jederfrau NNP cord-015369-72cjogxz 2161 6 / / SYM cord-015369-72cjogxz 2161 7 mann mann NNP cord-015369-72cjogxz 2162 1 bedienbare bedienbare NNP cord-015369-72cjogxz 2162 2 therapeutische therapeutische IN cord-015369-72cjogxz 2162 3 Option Option NNP cord-015369-72cjogxz 2162 4 zur zur NNP cord-015369-72cjogxz 2162 5 Versorgung Versorgung NNP cord-015369-72cjogxz 2162 6 peripherer peripherer NN cord-015369-72cjogxz 2162 7 Nervenverletzungen Nervenverletzungen NNP cord-015369-72cjogxz 2162 8 . . . cord-015369-72cjogxz 2163 1 Prevention prevention NN cord-015369-72cjogxz 2163 2 of of IN cord-015369-72cjogxz 2163 3 oxidative oxidative JJ cord-015369-72cjogxz 2163 4 stress stress NN cord-015369-72cjogxz 2163 5 induced induce VBD cord-015369-72cjogxz 2163 6 organ organ NN cord-015369-72cjogxz 2163 7 damage damage NN cord-015369-72cjogxz 2163 8 in in IN cord-015369-72cjogxz 2163 9 a a DT cord-015369-72cjogxz 2163 10 porcine porcine JJ cord-015369-72cjogxz 2163 11 brain brain NN cord-015369-72cjogxz 2163 12 dead dead JJ cord-015369-72cjogxz 2163 13 donor donor NN cord-015369-72cjogxz 2163 14 model model NN cord-015369-72cjogxz 2163 15 Background Background NNP cord-015369-72cjogxz 2163 16 . . . cord-015369-72cjogxz 2164 1 The the DT cord-015369-72cjogxz 2164 2 ' ' `` cord-015369-72cjogxz 2164 3 ' ' `` cord-015369-72cjogxz 2164 4 autonomic autonomic JJ cord-015369-72cjogxz 2164 5 storm storm NN cord-015369-72cjogxz 2164 6 ' ' '' cord-015369-72cjogxz 2164 7 ' ' '' cord-015369-72cjogxz 2164 8 initiated initiate VBN cord-015369-72cjogxz 2164 9 after after IN cord-015369-72cjogxz 2164 10 brain brain NN cord-015369-72cjogxz 2164 11 death death NN cord-015369-72cjogxz 2164 12 is be VBZ cord-015369-72cjogxz 2164 13 known know VBN cord-015369-72cjogxz 2164 14 to to TO cord-015369-72cjogxz 2164 15 induce induce VB cord-015369-72cjogxz 2164 16 a a DT cord-015369-72cjogxz 2164 17 cascade cascade NN cord-015369-72cjogxz 2164 18 of of IN cord-015369-72cjogxz 2164 19 chemokine chemokine NN cord-015369-72cjogxz 2164 20 and and CC cord-015369-72cjogxz 2164 21 cytokine cytokine NN cord-015369-72cjogxz 2164 22 release release NN cord-015369-72cjogxz 2164 23 which which WDT cord-015369-72cjogxz 2164 24 induces induce VBZ cord-015369-72cjogxz 2164 25 oxidative oxidative JJ cord-015369-72cjogxz 2164 26 stress stress NN cord-015369-72cjogxz 2164 27 and and CC cord-015369-72cjogxz 2164 28 consecutively consecutively RB cord-015369-72cjogxz 2164 29 causes cause VBZ cord-015369-72cjogxz 2164 30 cell cell NN cord-015369-72cjogxz 2164 31 damage damage NN cord-015369-72cjogxz 2164 32 and and CC cord-015369-72cjogxz 2164 33 diminished diminished JJ cord-015369-72cjogxz 2164 34 organ organ NN cord-015369-72cjogxz 2164 35 quality quality NN cord-015369-72cjogxz 2164 36 . . . cord-015369-72cjogxz 2165 1 Methods method NNS cord-015369-72cjogxz 2165 2 . . . cord-015369-72cjogxz 2166 1 Brain brain NN cord-015369-72cjogxz 2166 2 death death NN cord-015369-72cjogxz 2166 3 was be VBD cord-015369-72cjogxz 2166 4 induced induce VBN cord-015369-72cjogxz 2166 5 in in IN cord-015369-72cjogxz 2166 6 16 16 CD cord-015369-72cjogxz 2166 7 pigs pig NNS cord-015369-72cjogxz 2166 8 by by IN cord-015369-72cjogxz 2166 9 trepanation trepanation NN cord-015369-72cjogxz 2166 10 of of IN cord-015369-72cjogxz 2166 11 the the DT cord-015369-72cjogxz 2166 12 skull skull NN cord-015369-72cjogxz 2166 13 and and CC cord-015369-72cjogxz 2166 14 increasing increase VBG cord-015369-72cjogxz 2166 15 intracranial intracranial JJ cord-015369-72cjogxz 2166 16 pressure pressure NN cord-015369-72cjogxz 2166 17 until until IN cord-015369-72cjogxz 2166 18 brain brain NN cord-015369-72cjogxz 2166 19 stem stem NN cord-015369-72cjogxz 2166 20 herniation herniation NN cord-015369-72cjogxz 2166 21 occurred occur VBD cord-015369-72cjogxz 2166 22 . . . cord-015369-72cjogxz 2167 1 10 10 CD cord-015369-72cjogxz 2167 2 h h NN cord-015369-72cjogxz 2167 3 after after IN cord-015369-72cjogxz 2167 4 brain brain NN cord-015369-72cjogxz 2167 5 death death NN cord-015369-72cjogxz 2167 6 diagnosis diagnosis NN cord-015369-72cjogxz 2167 7 , , , cord-015369-72cjogxz 2167 8 the the DT cord-015369-72cjogxz 2167 9 pigs pig NNS cord-015369-72cjogxz 2167 10 were be VBD cord-015369-72cjogxz 2167 11 randomized randomize VBN cord-015369-72cjogxz 2167 12 in in IN cord-015369-72cjogxz 2167 13 two two CD cord-015369-72cjogxz 2167 14 groups group NNS cord-015369-72cjogxz 2167 15 ( ( -LRB- cord-015369-72cjogxz 2167 16 n n CC cord-015369-72cjogxz 2167 17 ¼ ¼ NNP cord-015369-72cjogxz 2167 18 8) 8) NNP cord-015369-72cjogxz 2167 19 . . . cord-015369-72cjogxz 2168 1 Group group NN cord-015369-72cjogxz 2168 2 1 1 CD cord-015369-72cjogxz 2168 3 was be VBD cord-015369-72cjogxz 2168 4 infused infuse VBN cord-015369-72cjogxz 2168 5 500 500 CD cord-015369-72cjogxz 2168 6 ml ml NNS cord-015369-72cjogxz 2168 7 of of IN cord-015369-72cjogxz 2168 8 a a DT cord-015369-72cjogxz 2168 9 solution solution NN cord-015369-72cjogxz 2168 10 containing contain VBG cord-015369-72cjogxz 2168 11 alpha alpha NN cord-015369-72cjogxz 2168 12 - - HYPH cord-015369-72cjogxz 2168 13 ketoglutaric ketoglutaric JJ cord-015369-72cjogxz 2168 14 acid acid NN cord-015369-72cjogxz 2168 15 and and CC cord-015369-72cjogxz 2168 16 5-MMF 5-mmf CD cord-015369-72cjogxz 2168 17 over over IN cord-015369-72cjogxz 2168 18 4 4 CD cord-015369-72cjogxz 2168 19 h h NNP cord-015369-72cjogxz 2168 20 whereas whereas IN cord-015369-72cjogxz 2168 21 group group NN cord-015369-72cjogxz 2168 22 2 2 CD cord-015369-72cjogxz 2168 23 received receive VBD cord-015369-72cjogxz 2168 24 500 500 CD cord-015369-72cjogxz 2168 25 ml ml NN cord-015369-72cjogxz 2168 26 NaCl nacl NN cord-015369-72cjogxz 2168 27 . . . cord-015369-72cjogxz 2169 1 Blood blood NN cord-015369-72cjogxz 2169 2 samples sample NNS cord-015369-72cjogxz 2169 3 were be VBD cord-015369-72cjogxz 2169 4 taken take VBN cord-015369-72cjogxz 2169 5 at at IN cord-015369-72cjogxz 2169 6 defined define VBN cord-015369-72cjogxz 2169 7 time time NN cord-015369-72cjogxz 2169 8 points point NNS cord-015369-72cjogxz 2169 9 , , , cord-015369-72cjogxz 2169 10 24 24 CD cord-015369-72cjogxz 2169 11 h h NN cord-015369-72cjogxz 2169 12 after after IN cord-015369-72cjogxz 2169 13 brain brain NN cord-015369-72cjogxz 2169 14 death death NN cord-015369-72cjogxz 2169 15 multiorgan multiorgan NNP cord-015369-72cjogxz 2169 16 donation donation NN cord-015369-72cjogxz 2169 17 was be VBD cord-015369-72cjogxz 2169 18 performed perform VBN cord-015369-72cjogxz 2169 19 and and CC cord-015369-72cjogxz 2169 20 tissue tissue NN cord-015369-72cjogxz 2169 21 samples sample NNS cord-015369-72cjogxz 2169 22 were be VBD cord-015369-72cjogxz 2169 23 taken take VBN cord-015369-72cjogxz 2169 24 immediately immediately RB cord-015369-72cjogxz 2169 25 after after IN cord-015369-72cjogxz 2169 26 organ organ NN cord-015369-72cjogxz 2169 27 retrieval retrieval NN cord-015369-72cjogxz 2169 28 and and CC cord-015369-72cjogxz 2169 29 after after IN cord-015369-72cjogxz 2169 30 cold cold JJ cord-015369-72cjogxz 2169 31 ischemia ischemia NN cord-015369-72cjogxz 2169 32 time time NN cord-015369-72cjogxz 2169 33 ( ( -LRB- cord-015369-72cjogxz 2169 34 CIT CIT NNP cord-015369-72cjogxz 2169 35 ) ) -RRB- cord-015369-72cjogxz 2169 36 . . . cord-015369-72cjogxz 2170 1 Histology histology NN cord-015369-72cjogxz 2170 2 and and CC cord-015369-72cjogxz 2170 3 immunohistochemistry immunohistochemistry NN cord-015369-72cjogxz 2170 4 were be VBD cord-015369-72cjogxz 2170 5 performed perform VBN cord-015369-72cjogxz 2170 6 to to TO cord-015369-72cjogxz 2170 7 quantify quantify VB cord-015369-72cjogxz 2170 8 occurrence occurrence NN cord-015369-72cjogxz 2170 9 of of IN cord-015369-72cjogxz 2170 10 apoptosis apoptosis NN cord-015369-72cjogxz 2170 11 and and CC cord-015369-72cjogxz 2170 12 of of IN cord-015369-72cjogxz 2170 13 oxidative oxidative JJ cord-015369-72cjogxz 2170 14 stress stress NN cord-015369-72cjogxz 2170 15 induced induce VBD cord-015369-72cjogxz 2170 16 cell cell NN cord-015369-72cjogxz 2170 17 damage damage NN cord-015369-72cjogxz 2170 18 . . . cord-015369-72cjogxz 2171 1 Results result NNS cord-015369-72cjogxz 2171 2 . . . cord-015369-72cjogxz 2172 1 Analysis analysis NN cord-015369-72cjogxz 2172 2 of of IN cord-015369-72cjogxz 2172 3 the the DT cord-015369-72cjogxz 2172 4 blood blood NN cord-015369-72cjogxz 2172 5 samples sample NNS cord-015369-72cjogxz 2172 6 allowed allow VBD cord-015369-72cjogxz 2172 7 us -PRON- PRP cord-015369-72cjogxz 2172 8 to to TO cord-015369-72cjogxz 2172 9 describe describe VB cord-015369-72cjogxz 2172 10 exactly exactly RB cord-015369-72cjogxz 2172 11 the the DT cord-015369-72cjogxz 2172 12 chemokine chemokine NN cord-015369-72cjogxz 2172 13 and and CC cord-015369-72cjogxz 2172 14 cytokine cytokine NN cord-015369-72cjogxz 2172 15 cascades cascade NNS cord-015369-72cjogxz 2172 16 initiated initiate VBN cord-015369-72cjogxz 2172 17 during during IN cord-015369-72cjogxz 2172 18 the the DT cord-015369-72cjogxz 2172 19 ' ' `` cord-015369-72cjogxz 2172 20 ' ' `` cord-015369-72cjogxz 2172 21 autonomic autonomic JJ cord-015369-72cjogxz 2172 22 storm storm NN cord-015369-72cjogxz 2172 23 ' ' '' cord-015369-72cjogxz 2172 24 ' ' '' cord-015369-72cjogxz 2172 25 in in IN cord-015369-72cjogxz 2172 26 this this DT cord-015369-72cjogxz 2172 27 pig pig NN cord-015369-72cjogxz 2172 28 brain brain NN cord-015369-72cjogxz 2172 29 dead dead JJ cord-015369-72cjogxz 2172 30 donor donor NN cord-015369-72cjogxz 2172 31 model model NN cord-015369-72cjogxz 2172 32 . . . cord-015369-72cjogxz 2173 1 Histology histology NN cord-015369-72cjogxz 2173 2 and and CC cord-015369-72cjogxz 2173 3 immunohistochemistry immunohistochemistry NN cord-015369-72cjogxz 2173 4 revealed reveal VBD cord-015369-72cjogxz 2173 5 significantly significantly RB cord-015369-72cjogxz 2173 6 lower low JJR cord-015369-72cjogxz 2173 7 apoptotic apoptotic JJ cord-015369-72cjogxz 2173 8 cells cell NNS cord-015369-72cjogxz 2173 9 as as RB cord-015369-72cjogxz 2173 10 well well RB cord-015369-72cjogxz 2173 11 as as IN cord-015369-72cjogxz 2173 12 lower low JJR cord-015369-72cjogxz 2173 13 anti anti JJ cord-015369-72cjogxz 2173 14 - - JJ cord-015369-72cjogxz 2173 15 nitrotyrosine nitrotyrosine JJ cord-015369-72cjogxz 2173 16 positive positive JJ cord-015369-72cjogxz 2173 17 cells cell NNS cord-015369-72cjogxz 2173 18 in in IN cord-015369-72cjogxz 2173 19 group group NN cord-015369-72cjogxz 2173 20 1 1 CD cord-015369-72cjogxz 2173 21 when when WRB cord-015369-72cjogxz 2173 22 compared compare VBN cord-015369-72cjogxz 2173 23 to to IN cord-015369-72cjogxz 2173 24 group group NN cord-015369-72cjogxz 2173 25 2 2 CD cord-015369-72cjogxz 2173 26 immediately immediately RB cord-015369-72cjogxz 2173 27 after after IN cord-015369-72cjogxz 2173 28 explanation explanation NN cord-015369-72cjogxz 2173 29 and and CC cord-015369-72cjogxz 2173 30 after after IN cord-015369-72cjogxz 2173 31 CIT CIT NNP cord-015369-72cjogxz 2173 32 . . . cord-015369-72cjogxz 2174 1 Conclusions conclusion NNS cord-015369-72cjogxz 2174 2 . . . cord-015369-72cjogxz 2175 1 We -PRON- PRP cord-015369-72cjogxz 2175 2 could could MD cord-015369-72cjogxz 2175 3 diminish diminish VB cord-015369-72cjogxz 2175 4 oxidative oxidative JJ cord-015369-72cjogxz 2175 5 stress stress NN cord-015369-72cjogxz 2175 6 induced induce VBN cord-015369-72cjogxz 2175 7 cell cell NN cord-015369-72cjogxz 2175 8 damage damage NN cord-015369-72cjogxz 2175 9 and and CC cord-015369-72cjogxz 2175 10 prevent prevent VB cord-015369-72cjogxz 2175 11 the the DT cord-015369-72cjogxz 2175 12 detrimental detrimental JJ cord-015369-72cjogxz 2175 13 effects effect NNS cord-015369-72cjogxz 2175 14 of of IN cord-015369-72cjogxz 2175 15 the the DT cord-015369-72cjogxz 2175 16 ' ' `` cord-015369-72cjogxz 2175 17 ' ' `` cord-015369-72cjogxz 2175 18 autonomic autonomic JJ cord-015369-72cjogxz 2175 19 storm storm NN cord-015369-72cjogxz 2175 20 ' ' '' cord-015369-72cjogxz 2175 21 ' ' '' cord-015369-72cjogxz 2175 22 by by IN cord-015369-72cjogxz 2175 23 applying apply VBG cord-015369-72cjogxz 2175 24 a a DT cord-015369-72cjogxz 2175 25 solution solution NN cord-015369-72cjogxz 2175 26 containing contain VBG cord-015369-72cjogxz 2175 27 alpha alpha NN cord-015369-72cjogxz 2175 28 - - HYPH cord-015369-72cjogxz 2175 29 ketoglutaric ketoglutaric JJ cord-015369-72cjogxz 2175 30 acid acid NN cord-015369-72cjogxz 2175 31 and and CC cord-015369-72cjogxz 2175 32 therefore therefore RB cord-015369-72cjogxz 2175 33 achieved achieve VBD cord-015369-72cjogxz 2175 34 better well JJR cord-015369-72cjogxz 2175 35 organ organ NN cord-015369-72cjogxz 2175 36 quality quality NN cord-015369-72cjogxz 2175 37 after after IN cord-015369-72cjogxz 2175 38 multiorgan multiorgan NNP cord-015369-72cjogxz 2175 39 donation donation NNP cord-015369-72cjogxz 2175 40 in in IN cord-015369-72cjogxz 2175 41 a a DT cord-015369-72cjogxz 2175 42 pig pig NN cord-015369-72cjogxz 2175 43 brain brain NN cord-015369-72cjogxz 2175 44 death death NN cord-015369-72cjogxz 2175 45 model model NN cord-015369-72cjogxz 2175 46 . . . cord-015369-72cjogxz 2176 1 Establishing establish VBG cord-015369-72cjogxz 2176 2 a a DT cord-015369-72cjogxz 2176 3 brain brain NN cord-015369-72cjogxz 2176 4 death death NN cord-015369-72cjogxz 2176 5 donor donor NN cord-015369-72cjogxz 2176 6 model model NN cord-015369-72cjogxz 2176 7 in in IN cord-015369-72cjogxz 2176 8 pigs pig NNS cord-015369-72cjogxz 2176 9 Background Background NNP cord-015369-72cjogxz 2176 10 . . . cord-015369-72cjogxz 2177 1 Several several JJ cord-015369-72cjogxz 2177 2 factors factor NNS cord-015369-72cjogxz 2177 3 influencing influence VBG cord-015369-72cjogxz 2177 4 organ organ NN cord-015369-72cjogxz 2177 5 quality quality NN cord-015369-72cjogxz 2177 6 and and CC cord-015369-72cjogxz 2177 7 recipient recipient NN cord-015369-72cjogxz 2177 8 survival survival NN cord-015369-72cjogxz 2177 9 after after IN cord-015369-72cjogxz 2177 10 multiorgan multiorgan NNP cord-015369-72cjogxz 2177 11 donation donation NN cord-015369-72cjogxz 2177 12 and and CC cord-015369-72cjogxz 2177 13 transplantation transplantation NN cord-015369-72cjogxz 2177 14 are be VBP cord-015369-72cjogxz 2177 15 still still RB cord-015369-72cjogxz 2177 16 unknown unknown JJ cord-015369-72cjogxz 2177 17 and and CC cord-015369-72cjogxz 2177 18 difficult difficult JJ cord-015369-72cjogxz 2177 19 to to TO cord-015369-72cjogxz 2177 20 investigate investigate VB cord-015369-72cjogxz 2177 21 in in IN cord-015369-72cjogxz 2177 22 humans human NNS cord-015369-72cjogxz 2177 23 . . . cord-015369-72cjogxz 2178 1 Therefore therefore RB cord-015369-72cjogxz 2178 2 the the DT cord-015369-72cjogxz 2178 3 need need NN cord-015369-72cjogxz 2178 4 for for IN cord-015369-72cjogxz 2178 5 an an DT cord-015369-72cjogxz 2178 6 animal animal NN cord-015369-72cjogxz 2178 7 model model NN cord-015369-72cjogxz 2178 8 that that WDT cord-015369-72cjogxz 2178 9 imitates imitate VBZ cord-015369-72cjogxz 2178 10 human human JJ cord-015369-72cjogxz 2178 11 conditions condition NNS cord-015369-72cjogxz 2178 12 might may MD cord-015369-72cjogxz 2178 13 be be VB cord-015369-72cjogxz 2178 14 useful useful JJ cord-015369-72cjogxz 2178 15 not not RB cord-015369-72cjogxz 2178 16 only only RB cord-015369-72cjogxz 2178 17 to to TO cord-015369-72cjogxz 2178 18 be be VB cord-015369-72cjogxz 2178 19 able able JJ cord-015369-72cjogxz 2178 20 to to TO cord-015369-72cjogxz 2178 21 monitor monitor VB cord-015369-72cjogxz 2178 22 pathomechanisms pathomechanism NNS cord-015369-72cjogxz 2178 23 of of IN cord-015369-72cjogxz 2178 24 brain brain NN cord-015369-72cjogxz 2178 25 death death NN cord-015369-72cjogxz 2178 26 and and CC cord-015369-72cjogxz 2178 27 biochemical biochemical JJ cord-015369-72cjogxz 2178 28 cascades cascade NNS cord-015369-72cjogxz 2178 29 in in IN cord-015369-72cjogxz 2178 30 the the DT cord-015369-72cjogxz 2178 31 organisms organism NNS cord-015369-72cjogxz 2178 32 after after IN cord-015369-72cjogxz 2178 33 brain brain NN cord-015369-72cjogxz 2178 34 death death NN cord-015369-72cjogxz 2178 35 but but CC cord-015369-72cjogxz 2178 36 also also RB cord-015369-72cjogxz 2178 37 to to TO cord-015369-72cjogxz 2178 38 be be VB cord-015369-72cjogxz 2178 39 able able JJ cord-015369-72cjogxz 2178 40 to to TO cord-015369-72cjogxz 2178 41 investigate investigate VB cord-015369-72cjogxz 2178 42 novel novel JJ cord-015369-72cjogxz 2178 43 strategies strategy NNS cord-015369-72cjogxz 2178 44 to to TO cord-015369-72cjogxz 2178 45 ameliorate ameliorate VB cord-015369-72cjogxz 2178 46 organ organ NN cord-015369-72cjogxz 2178 47 quality quality NN cord-015369-72cjogxz 2178 48 and and CC cord-015369-72cjogxz 2178 49 functionality functionality NN cord-015369-72cjogxz 2178 50 after after IN cord-015369-72cjogxz 2178 51 multiorgan multiorgan NNP cord-015369-72cjogxz 2178 52 donation donation NNP cord-015369-72cjogxz 2178 53 . . . cord-015369-72cjogxz 2179 1 Methods method NNS cord-015369-72cjogxz 2179 2 . . . cord-015369-72cjogxz 2180 1 In in IN cord-015369-72cjogxz 2180 2 16 16 CD cord-015369-72cjogxz 2180 3 pigs pig NNS cord-015369-72cjogxz 2180 4 brain brain NN cord-015369-72cjogxz 2180 5 death death NN cord-015369-72cjogxz 2180 6 was be VBD cord-015369-72cjogxz 2180 7 induced induce VBN cord-015369-72cjogxz 2180 8 by by IN cord-015369-72cjogxz 2180 9 inserting insert VBG cord-015369-72cjogxz 2180 10 a a DT cord-015369-72cjogxz 2180 11 catheter catheter NN cord-015369-72cjogxz 2180 12 into into IN cord-015369-72cjogxz 2180 13 the the DT cord-015369-72cjogxz 2180 14 intracranial intracranial JJ cord-015369-72cjogxz 2180 15 space space NN cord-015369-72cjogxz 2180 16 after after IN cord-015369-72cjogxz 2180 17 trepanation trepanation NN cord-015369-72cjogxz 2180 18 of of IN cord-015369-72cjogxz 2180 19 the the DT cord-015369-72cjogxz 2180 20 skull skull NN cord-015369-72cjogxz 2180 21 and and CC cord-015369-72cjogxz 2180 22 augmenting augment VBG cord-015369-72cjogxz 2180 23 intracranial intracranial JJ cord-015369-72cjogxz 2180 24 pressure pressure NN cord-015369-72cjogxz 2180 25 until until IN cord-015369-72cjogxz 2180 26 brain brain NN cord-015369-72cjogxz 2180 27 stem stem NN cord-015369-72cjogxz 2180 28 herniation herniation NN cord-015369-72cjogxz 2180 29 occurred occur VBD cord-015369-72cjogxz 2180 30 . . . cord-015369-72cjogxz 2181 1 Intracranial intracranial JJ cord-015369-72cjogxz 2181 2 pressure pressure NN cord-015369-72cjogxz 2181 3 was be VBD cord-015369-72cjogxz 2181 4 monitored monitor VBN cord-015369-72cjogxz 2181 5 continuously continuously RB cord-015369-72cjogxz 2181 6 and and CC cord-015369-72cjogxz 2181 7 after after IN cord-015369-72cjogxz 2181 8 60 60 CD cord-015369-72cjogxz 2181 9 min min NN cord-015369-72cjogxz 2181 10 brain brain NN cord-015369-72cjogxz 2181 11 death death NN cord-015369-72cjogxz 2181 12 diagnostics diagnostic NNS cord-015369-72cjogxz 2181 13 was be VBD cord-015369-72cjogxz 2181 14 performed perform VBN cord-015369-72cjogxz 2181 15 by by IN cord-015369-72cjogxz 2181 16 a a DT cord-015369-72cjogxz 2181 17 neurologist neurologist NN cord-015369-72cjogxz 2181 18 including include VBG cord-015369-72cjogxz 2181 19 EEG EEG NNP cord-015369-72cjogxz 2181 20 examination examination NN cord-015369-72cjogxz 2181 21 and and CC cord-015369-72cjogxz 2181 22 clinical clinical JJ cord-015369-72cjogxz 2181 23 examination examination NN cord-015369-72cjogxz 2181 24 . . . cord-015369-72cjogxz 2182 1 Donor donor NN cord-015369-72cjogxz 2182 2 care care NN cord-015369-72cjogxz 2182 3 was be VBD cord-015369-72cjogxz 2182 4 performed perform VBN cord-015369-72cjogxz 2182 5 according accord VBG cord-015369-72cjogxz 2182 6 to to IN cord-015369-72cjogxz 2182 7 standard standard JJ cord-015369-72cjogxz 2182 8 guidelines guideline NNS cord-015369-72cjogxz 2182 9 for for IN cord-015369-72cjogxz 2182 10 24 24 CD cord-015369-72cjogxz 2182 11 h. h. NN cord-015369-72cjogxz 2182 12 Results result NNS cord-015369-72cjogxz 2182 13 . . . cord-015369-72cjogxz 2183 1 60 60 CD cord-015369-72cjogxz 2183 2 min min NN cord-015369-72cjogxz 2183 3 after after IN cord-015369-72cjogxz 2183 4 brain brain NN cord-015369-72cjogxz 2183 5 death death NN cord-015369-72cjogxz 2183 6 induction induction NN cord-015369-72cjogxz 2183 7 neurological neurological JJ cord-015369-72cjogxz 2183 8 examination examination NN cord-015369-72cjogxz 2183 9 and and CC cord-015369-72cjogxz 2183 10 EEG EEG NNP cord-015369-72cjogxz 2183 11 examination examination NN cord-015369-72cjogxz 2183 12 confirmed confirm VBD cord-015369-72cjogxz 2183 13 brain brain NN cord-015369-72cjogxz 2183 14 death death NN cord-015369-72cjogxz 2183 15 . . . cord-015369-72cjogxz 2184 1 All all DT cord-015369-72cjogxz 2184 2 16 16 CD cord-015369-72cjogxz 2184 3 animals animal NNS cord-015369-72cjogxz 2184 4 showed show VBD cord-015369-72cjogxz 2184 5 typical typical JJ cord-015369-72cjogxz 2184 6 signs sign NNS cord-015369-72cjogxz 2184 7 of of IN cord-015369-72cjogxz 2184 8 brain brain NN cord-015369-72cjogxz 2184 9 death death NN cord-015369-72cjogxz 2184 10 . . . cord-015369-72cjogxz 2185 1 All all DT cord-015369-72cjogxz 2185 2 symptoms symptom NNS cord-015369-72cjogxz 2185 3 could could MD cord-015369-72cjogxz 2185 4 be be VB cord-015369-72cjogxz 2185 5 treated treat VBN cord-015369-72cjogxz 2185 6 using use VBG cord-015369-72cjogxz 2185 7 standard standard JJ cord-015369-72cjogxz 2185 8 medication medication NN cord-015369-72cjogxz 2185 9 . . . cord-015369-72cjogxz 2186 1 After after IN cord-015369-72cjogxz 2186 2 24 24 CD cord-015369-72cjogxz 2186 3 h h NN cord-015369-72cjogxz 2186 4 of of IN cord-015369-72cjogxz 2186 5 brain brain NN cord-015369-72cjogxz 2186 6 death death NN cord-015369-72cjogxz 2186 7 successful successful JJ cord-015369-72cjogxz 2186 8 multiorgan multiorgan NNP cord-015369-72cjogxz 2186 9 donation donation NN cord-015369-72cjogxz 2186 10 was be VBD cord-015369-72cjogxz 2186 11 performed perform VBN cord-015369-72cjogxz 2186 12 . . . cord-015369-72cjogxz 2187 1 After after IN cord-015369-72cjogxz 2187 2 organ organ NN cord-015369-72cjogxz 2187 3 retrieval retrieval NN cord-015369-72cjogxz 2187 4 , , , cord-015369-72cjogxz 2187 5 abdominal abdominal JJ cord-015369-72cjogxz 2187 6 and and CC cord-015369-72cjogxz 2187 7 thoracic thoracic JJ cord-015369-72cjogxz 2187 8 organs organ NNS cord-015369-72cjogxz 2187 9 could could MD cord-015369-72cjogxz 2187 10 be be VB cord-015369-72cjogxz 2187 11 analysed analyse VBN cord-015369-72cjogxz 2187 12 for for IN cord-015369-72cjogxz 2187 13 tissue tissue NN cord-015369-72cjogxz 2187 14 damage damage NN cord-015369-72cjogxz 2187 15 and and CC cord-015369-72cjogxz 2187 16 organ organ NN cord-015369-72cjogxz 2187 17 quality quality NN cord-015369-72cjogxz 2187 18 . . . cord-015369-72cjogxz 2188 1 Conclusions conclusion NNS cord-015369-72cjogxz 2188 2 . . . cord-015369-72cjogxz 2189 1 Using use VBG cord-015369-72cjogxz 2189 2 this this DT cord-015369-72cjogxz 2189 3 method method NN cord-015369-72cjogxz 2189 4 , , , cord-015369-72cjogxz 2189 5 a a DT cord-015369-72cjogxz 2189 6 suitable suitable JJ cord-015369-72cjogxz 2189 7 brain brain NN cord-015369-72cjogxz 2189 8 death death NN cord-015369-72cjogxz 2189 9 donor donor NN cord-015369-72cjogxz 2189 10 model model NN cord-015369-72cjogxz 2189 11 could could MD cord-015369-72cjogxz 2189 12 be be VB cord-015369-72cjogxz 2189 13 establish establish VBN cord-015369-72cjogxz 2189 14 that that WDT cord-015369-72cjogxz 2189 15 will will MD cord-015369-72cjogxz 2189 16 enable enable VB cord-015369-72cjogxz 2189 17 us -PRON- PRP cord-015369-72cjogxz 2189 18 not not RB cord-015369-72cjogxz 2189 19 only only RB cord-015369-72cjogxz 2189 20 to to TO cord-015369-72cjogxz 2189 21 investigate investigate VB cord-015369-72cjogxz 2189 22 in in IN cord-015369-72cjogxz 2189 23 detail detail NN cord-015369-72cjogxz 2189 24 effects effect NNS cord-015369-72cjogxz 2189 25 and and CC cord-015369-72cjogxz 2189 26 pathophysiology pathophysiology NN cord-015369-72cjogxz 2189 27 after after IN cord-015369-72cjogxz 2189 28 occurrence occurrence NN cord-015369-72cjogxz 2189 29 of of IN cord-015369-72cjogxz 2189 30 brain brain NN cord-015369-72cjogxz 2189 31 death death NN cord-015369-72cjogxz 2189 32 but but CC cord-015369-72cjogxz 2189 33 also also RB cord-015369-72cjogxz 2189 34 to to TO cord-015369-72cjogxz 2189 35 evaluate evaluate VB cord-015369-72cjogxz 2189 36 new new JJ cord-015369-72cjogxz 2189 37 strategies strategy NNS cord-015369-72cjogxz 2189 38 to to TO cord-015369-72cjogxz 2189 39 ameliorate ameliorate VB cord-015369-72cjogxz 2189 40 organ organ NN cord-015369-72cjogxz 2189 41 quality quality NN cord-015369-72cjogxz 2189 42 and and CC cord-015369-72cjogxz 2189 43 even even RB cord-015369-72cjogxz 2189 44 to to TO cord-015369-72cjogxz 2189 45 enlarge enlarge VB cord-015369-72cjogxz 2189 46 the the DT cord-015369-72cjogxz 2189 47 donor donor NN cord-015369-72cjogxz 2189 48 pool pool NN cord-015369-72cjogxz 2189 49 for for IN cord-015369-72cjogxz 2189 50 multiorgan multiorgan NNP cord-015369-72cjogxz 2189 51 donation donation NNP cord-015369-72cjogxz 2189 52 . . . cord-015369-72cjogxz 2190 1 Behandlung Behandlung NNP cord-015369-72cjogxz 2190 2 von von NNP cord-015369-72cjogxz 2190 3 gastrojejunalen gastrojejunalen NNP cord-015369-72cjogxz 2191 1 Anastomosenleaks Anastomosenleaks NNP cord-015369-72cjogxz 2192 1 nach nach NNP cord-015369-72cjogxz 2192 2 Roux Roux NNP cord-015369-72cjogxz 2192 3 - - HYPH cord-015369-72cjogxz 2192 4 n n NNP cord-015369-72cjogxz 2192 5 - - HYPH cord-015369-72cjogxz 2192 6 Y Y NNP cord-015369-72cjogxz 2192 7 Magenbypass Magenbypass NNP cord-015369-72cjogxz 2192 8 mit mit XX cord-015369-72cjogxz 2192 9 einem einem NNP cord-015369-72cjogxz 2193 1 oder oder NNP cord-015369-72cjogxz 2193 2 zwei zwei NNP cord-015369-72cjogxz 2194 1 überlappenden überlappenden NNP cord-015369-72cjogxz 2194 2 beschichteten beschichteten NNP cord-015369-72cjogxz 2194 3 Metallstents Metallstents NNP cord-015369-72cjogxz 2195 1 i -PRON- PRP cord-015369-72cjogxz 2195 2 m be VBP cord-015369-72cjogxz 2195 3 Schweinemodell Schweinemodell NNP cord-015369-72cjogxz 2195 4 Methodik Methodik NNP cord-015369-72cjogxz 2195 5 . . . cord-015369-72cjogxz 2196 1 In in IN cord-015369-72cjogxz 2196 2 8 8 CD cord-015369-72cjogxz 2196 3 Hausschweine Hausschweine NNP cord-015369-72cjogxz 2196 4 wurde wurde NN cord-015369-72cjogxz 2196 5 eine eine NNP cord-015369-72cjogxz 2196 6 Roux Roux NNP cord-015369-72cjogxz 2196 7 - - HYPH cord-015369-72cjogxz 2196 8 n n NNP cord-015369-72cjogxz 2196 9 - - HYPH cord-015369-72cjogxz 2196 10 Y Y NNP cord-015369-72cjogxz 2196 11 Magenbypass Magenbypass NNP cord-015369-72cjogxz 2196 12 hergestellt hergestellt NN cord-015369-72cjogxz 2196 13 . . . cord-015369-72cjogxz 2197 1 In in IN cord-015369-72cjogxz 2197 2 vier vier NNP cord-015369-72cjogxz 2197 3 Tieren Tieren NNP cord-015369-72cjogxz 2197 4 wurde wurde NN cord-015369-72cjogxz 2197 5 die die VBP cord-015369-72cjogxz 2197 6 GJ GJ NNP cord-015369-72cjogxz 2197 7 mit mit NNP cord-015369-72cjogxz 2197 8 einem einem NNP cord-015369-72cjogxz 2197 9 1 1 CD cord-015369-72cjogxz 2197 10 cm cm NNP cord-015369-72cjogxz 2197 11 Leak leak VB cord-015369-72cjogxz 2197 12 an an DT cord-015369-72cjogxz 2197 13 der der NN cord-015369-72cjogxz 2197 14 Pouchhinterwand Pouchhinterwand NNP cord-015369-72cjogxz 2197 15 ( ( -LRB- cord-015369-72cjogxz 2197 16 retrogastrisch retrogastrisch NNP cord-015369-72cjogxz 2197 17 ) ) -RRB- cord-015369-72cjogxz 2197 18 hergestellt hergestellt NNP cord-015369-72cjogxz 2197 19 . . . cord-015369-72cjogxz 2198 1 In in IN cord-015369-72cjogxz 2198 2 zwei zwei NNP cord-015369-72cjogxz 2198 3 Tieren Tieren NNP cord-015369-72cjogxz 2198 4 wurde wurde NN cord-015369-72cjogxz 2198 5 ein ein NNP cord-015369-72cjogxz 2198 6 Stent Stent NNP cord-015369-72cjogxz 2198 7 platziert platziert NNP cord-015369-72cjogxz 2198 8 , , , cord-015369-72cjogxz 2198 9 die die VB cord-015369-72cjogxz 2198 10 anderen anderen NNP cord-015369-72cjogxz 2198 11 beiden beiden NNP cord-015369-72cjogxz 2199 1 Tiere Tiere NNP cord-015369-72cjogxz 2199 2 wurden wurden VBD cord-015369-72cjogxz 2199 3 ohne ohne NNP cord-015369-72cjogxz 2199 4 Stent Stent NNP cord-015369-72cjogxz 2199 5 belassen belassen NNP cord-015369-72cjogxz 2199 6 . . . cord-015369-72cjogxz 2200 1 In in IN cord-015369-72cjogxz 2200 2 vier vier NNP cord-015369-72cjogxz 2200 3 Tieren Tieren NNP cord-015369-72cjogxz 2200 4 wurde wurde VBD cord-015369-72cjogxz 2200 5 eine eine NNP cord-015369-72cjogxz 2200 6 GJ GJ NNP cord-015369-72cjogxz 2200 7 mit mit NNP cord-015369-72cjogxz 2200 8 Leak Leak NNP cord-015369-72cjogxz 2200 9 an an DT cord-015369-72cjogxz 2200 10 der der NNP cord-015369-72cjogxz 2200 11 Pouchvorderwand Pouchvorderwand NNP cord-015369-72cjogxz 2200 12 ( ( -LRB- cord-015369-72cjogxz 2200 13 anterogastrisch anterogastrisch NNP cord-015369-72cjogxz 2200 14 ) ) -RRB- cord-015369-72cjogxz 2200 15 angelegt angelegt NNP cord-015369-72cjogxz 2200 16 , , , cord-015369-72cjogxz 2200 17 in in IN cord-015369-72cjogxz 2200 18 zwei zwei NNP cord-015369-72cjogxz 2200 19 dieser dieser NNP cord-015369-72cjogxz 2200 20 Tiere Tiere NNP cord-015369-72cjogxz 2200 21 wurde wurde NN cord-015369-72cjogxz 2200 22 ein ein NNP cord-015369-72cjogxz 2200 23 Stent Stent NNP cord-015369-72cjogxz 2200 24 und und IN cord-015369-72cjogxz 2200 25 in in IN cord-015369-72cjogxz 2200 26 zwei zwei NNP cord-015369-72cjogxz 2200 27 Tieren Tieren NNP cord-015369-72cjogxz 2200 28 jeweils jeweils NNP cord-015369-72cjogxz 2200 29 2 2 CD cord-015369-72cjogxz 2200 30 überlappende überlappende NNP cord-015369-72cjogxz 2200 31 Stents Stents NNPS cord-015369-72cjogxz 2200 32 platziert platziert JJ cord-015369-72cjogxz 2200 33 . . . cord-015369-72cjogxz 2201 1 Nach Nach NNP cord-015369-72cjogxz 2201 2 2 2 CD cord-015369-72cjogxz 2201 3 Wochen Wochen NNP cord-015369-72cjogxz 2201 4 erfolgte erfolgte NN cord-015369-72cjogxz 2201 5 die die VBP cord-015369-72cjogxz 2201 6 Euthanasie Euthanasie NNP cord-015369-72cjogxz 2201 7 und und IN cord-015369-72cjogxz 2201 8 Obduktion Obduktion NNP cord-015369-72cjogxz 2201 9 . . . cord-015369-72cjogxz 2202 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2202 2 . . . cord-015369-72cjogxz 2203 1 Die die VB cord-015369-72cjogxz 2203 2 Stentplatzierung Stentplatzierung NNP cord-015369-72cjogxz 2203 3 war war NN cord-015369-72cjogxz 2203 4 in in IN cord-015369-72cjogxz 2203 5 allen allen NNP cord-015369-72cjogxz 2203 6 Tieren Tieren NNP cord-015369-72cjogxz 2203 7 erfolgreich erfolgreich NNP cord-015369-72cjogxz 2203 8 . . . cord-015369-72cjogxz 2204 1 In in IN cord-015369-72cjogxz 2204 2 der der NNP cord-015369-72cjogxz 2204 3 retrogastrischen retrogastrischen NNP cord-015369-72cjogxz 2204 4 Gruppe Gruppe NNP cord-015369-72cjogxz 2204 5 überlebten überlebten NN cord-015369-72cjogxz 2204 6 beide beide NNP cord-015369-72cjogxz 2204 7 Tiere Tiere NNP cord-015369-72cjogxz 2204 8 ohne ohne NNP cord-015369-72cjogxz 2204 9 Stents Stents NNP cord-015369-72cjogxz 2204 10 ohne ohne NNP cord-015369-72cjogxz 2204 11 Komplikationen Komplikationen NNP cord-015369-72cjogxz 2204 12 mit mit NNP cord-015369-72cjogxz 2204 13 Abheilung Abheilung NNP cord-015369-72cjogxz 2204 14 der der NNP cord-015369-72cjogxz 2204 15 Leaks leak NNS cord-015369-72cjogxz 2204 16 , , , cord-015369-72cjogxz 2204 17 während während NNP cord-015369-72cjogxz 2204 18 die die VBP cord-015369-72cjogxz 2205 1 Tiere Tiere NNP cord-015369-72cjogxz 2205 2 mit mit NNP cord-015369-72cjogxz 2205 3 Stents stent NNS cord-015369-72cjogxz 2205 4 am be VBP cord-015369-72cjogxz 2205 5 4 4 CD cord-015369-72cjogxz 2205 6 . . . cord-015369-72cjogxz 2206 1 und und IN cord-015369-72cjogxz 2206 2 5 5 CD cord-015369-72cjogxz 2206 3 . . . cord-015369-72cjogxz 2207 1 postoperativen postoperativen NNP cord-015369-72cjogxz 2207 2 Tag Tag NNP cord-015369-72cjogxz 2207 3 aufgrund aufgrund NNP cord-015369-72cjogxz 2208 1 von von NNP cord-015369-72cjogxz 2208 2 Kinking Kinking NNP cord-015369-72cjogxz 2208 3 mit mit NNP cord-015369-72cjogxz 2208 4 Obstruktion Obstruktion NNP cord-015369-72cjogxz 2208 5 und und XX cord-015369-72cjogxz 2209 1 Drucknekrosen Drucknekrosen NNP cord-015369-72cjogxz 2209 2 des des FW cord-015369-72cjogxz 2209 3 Roux Roux NNP cord-015369-72cjogxz 2209 4 - - HYPH cord-015369-72cjogxz 2209 5 Schenkels Schenkels NNP cord-015369-72cjogxz 2209 6 verstarben verstarben NN cord-015369-72cjogxz 2209 7 . . . cord-015369-72cjogxz 2210 1 In in IN cord-015369-72cjogxz 2210 2 der der NNP cord-015369-72cjogxz 2210 3 anterogastrischen anterogastrischen NNP cord-015369-72cjogxz 2210 4 Gruppe Gruppe NNP cord-015369-72cjogxz 2210 5 überlebte überlebte NNP cord-015369-72cjogxz 2211 1 ein ein NNP cord-015369-72cjogxz 2211 2 Tier Tier NNP cord-015369-72cjogxz 2211 3 mit mit NNP cord-015369-72cjogxz 2211 4 Abheilung Abheilung NNP cord-015369-72cjogxz 2211 5 des des NNP cord-015369-72cjogxz 2211 6 Leaks leak NNS cord-015369-72cjogxz 2211 7 , , , cord-015369-72cjogxz 2211 8 jedoch jedoch NNP cord-015369-72cjogxz 2211 9 mit mit NNP cord-015369-72cjogxz 2211 10 Stentmigration Stentmigration NNP cord-015369-72cjogxz 2211 11 nach nach NNP cord-015369-72cjogxz 2211 12 distal distal JJ cord-015369-72cjogxz 2211 13 . . . cord-015369-72cjogxz 2212 1 Die die VB cord-015369-72cjogxz 2212 2 übrigen übrigen NNP cord-015369-72cjogxz 2213 1 3 3 CD cord-015369-72cjogxz 2213 2 Tiere Tiere NNP cord-015369-72cjogxz 2213 3 verstarben verstarben NN cord-015369-72cjogxz 2213 4 zwischen zwischen NNP cord-015369-72cjogxz 2213 5 dem dem NNP cord-015369-72cjogxz 2213 6 4 4 CD cord-015369-72cjogxz 2213 7 . . . cord-015369-72cjogxz 2214 1 und und IN cord-015369-72cjogxz 2214 2 6 6 CD cord-015369-72cjogxz 2214 3 . . . cord-015369-72cjogxz 2215 1 postoperativen postoperativen NNP cord-015369-72cjogxz 2216 1 Tag tag NN cord-015369-72cjogxz 2216 2 . . . cord-015369-72cjogxz 2217 1 In in IN cord-015369-72cjogxz 2217 2 allen allen NNP cord-015369-72cjogxz 2217 3 fanden fanden NNP cord-015369-72cjogxz 2217 4 sich sich NNP cord-015369-72cjogxz 2217 5 durch durch NNP cord-015369-72cjogxz 2217 6 das das NNP cord-015369-72cjogxz 2217 7 distale distale NN cord-015369-72cjogxz 2217 8 Stentende Stentende NNP cord-015369-72cjogxz 2217 9 bedingte bedingte NN cord-015369-72cjogxz 2217 10 Drucknekrosen Drucknekrosen NNP cord-015369-72cjogxz 2217 11 . . . cord-015369-72cjogxz 2218 1 In in IN cord-015369-72cjogxz 2218 2 einem einem NNP cord-015369-72cjogxz 2218 3 Tier Tier NNP cord-015369-72cjogxz 2218 4 mit mit NNP cord-015369-72cjogxz 2218 5 einem einem NNP cord-015369-72cjogxz 2218 6 Stent Stent NNP cord-015369-72cjogxz 2218 7 fand fand NN cord-015369-72cjogxz 2218 8 sich sich NNP cord-015369-72cjogxz 2218 9 Peritonitis peritonitis NN cord-015369-72cjogxz 2218 10 bei bei NNP cord-015369-72cjogxz 2218 11 persistierendem persistierendem NN cord-015369-72cjogxz 2218 12 Leakage leakage NN cord-015369-72cjogxz 2218 13 . . . cord-015369-72cjogxz 2219 1 In in IN cord-015369-72cjogxz 2219 2 Tieren Tieren NNP cord-015369-72cjogxz 2219 3 mit mit NNP cord-015369-72cjogxz 2219 4 zwei zwei NNP cord-015369-72cjogxz 2219 5 Stents stent NNS cord-015369-72cjogxz 2219 6 fand fand VBP cord-015369-72cjogxz 2219 7 sich sich NNP cord-015369-72cjogxz 2219 8 einem einem NNP cord-015369-72cjogxz 2219 9 ein ein NNP cord-015369-72cjogxz 2219 10 Leck Leck NNP cord-015369-72cjogxz 2219 11 der der NNP cord-015369-72cjogxz 2219 12 Fußpunktanastomose Fußpunktanastomose NNP cord-015369-72cjogxz 2219 13 und und IN cord-015369-72cjogxz 2219 14 in in IN cord-015369-72cjogxz 2219 15 dem dem NNP cord-015369-72cjogxz 2219 16 anderen anderen NNP cord-015369-72cjogxz 2219 17 eine eine NNP cord-015369-72cjogxz 2219 18 Obstruktion Obstruktion NNP cord-015369-72cjogxz 2219 19 durch durch NNP cord-015369-72cjogxz 2219 20 Kinking Kinking NNP cord-015369-72cjogxz 2219 21 des des FW cord-015369-72cjogxz 2219 22 Roux Roux NNP cord-015369-72cjogxz 2219 23 - - HYPH cord-015369-72cjogxz 2219 24 Schenkels Schenkels NNPS cord-015369-72cjogxz 2219 25 . . . cord-015369-72cjogxz 2220 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 2220 2 . . . cord-015369-72cjogxz 2221 1 Während während JJ cord-015369-72cjogxz 2221 2 lokale lokale NN cord-015369-72cjogxz 2221 3 Verschiebelappen Verschiebelappen NNP cord-015369-72cjogxz 2221 4 die die VBP cord-015369-72cjogxz 2221 5 besten besten NNP cord-015369-72cjogxz 2221 6 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2221 7 bezüglich bezüglich NNP cord-015369-72cjogxz 2221 8 der der NNP cord-015369-72cjogxz 2221 9 Hauttextur Hauttextur NNP cord-015369-72cjogxz 2221 10 ergeben ergeben NN cord-015369-72cjogxz 2221 11 , , , cord-015369-72cjogxz 2221 12 ist ist FW cord-015369-72cjogxz 2221 13 bei bei NNP cord-015369-72cjogxz 2221 14 ausgedehnten ausgedehnten NNP cord-015369-72cjogxz 2221 15 Defekten Defekten NNP cord-015369-72cjogxz 2221 16 mit mit NNP cord-015369-72cjogxz 2221 17 lokalen lokalen NNP cord-015369-72cjogxz 2221 18 Verziehungen Verziehungen NNP cord-015369-72cjogxz 2221 19 und und IN cord-015369-72cjogxz 2221 20 Formgebungsproblemen Formgebungsproblemen NNP cord-015369-72cjogxz 2221 21 zu zu NNP cord-015369-72cjogxz 2221 22 rechnen rechnen NNP cord-015369-72cjogxz 2221 23 . . . cord-015369-72cjogxz 2222 1 Mikrovaskuläre Mikrovaskuläre NNP cord-015369-72cjogxz 2222 2 Ferntransplantate Ferntransplantate NNP cord-015369-72cjogxz 2222 3 zeigen zeigen NNP cord-015369-72cjogxz 2223 1 i -PRON- PRP cord-015369-72cjogxz 2223 2 m be VBP cord-015369-72cjogxz 2223 3 Gegensatz Gegensatz NNP cord-015369-72cjogxz 2223 4 dazu dazu NNP cord-015369-72cjogxz 2223 5 häufig häufig NNP cord-015369-72cjogxz 2224 1 eine eine NNP cord-015369-72cjogxz 2224 2 andere andere NNP cord-015369-72cjogxz 2224 3 Spenderregion Spenderregion NNP cord-015369-72cjogxz 2224 4 - - HYPH cord-015369-72cjogxz 2224 5 abhängige abhängige NNP cord-015369-72cjogxz 2224 6 Hauttextur Hauttextur NNP cord-015369-72cjogxz 2224 7 . . . cord-015369-72cjogxz 2225 1 Der Der NNP cord-015369-72cjogxz 2225 2 Submentale Submentale NNP cord-015369-72cjogxz 2225 3 Insellappen Insellappen NNP cord-015369-72cjogxz 2225 4 bietet bietet NNP cord-015369-72cjogxz 2226 1 i -PRON- PRP cord-015369-72cjogxz 2226 2 m be VBP cord-015369-72cjogxz 2226 3 Gegensatz Gegensatz NNP cord-015369-72cjogxz 2226 4 dazu dazu NNP cord-015369-72cjogxz 2226 5 eine eine NNP cord-015369-72cjogxz 2226 6 Alternative Alternative NNP cord-015369-72cjogxz 2226 7 zu zu NNP cord-015369-72cjogxz 2226 8 den den NN cord-015369-72cjogxz 2226 9 genannten genannten NNP cord-015369-72cjogxz 2226 10 Verfahren Verfahren NNP cord-015369-72cjogxz 2226 11 . . . cord-015369-72cjogxz 2227 1 In in IN cord-015369-72cjogxz 2227 2 diesem diesem JJ cord-015369-72cjogxz 2227 3 Vortrag Vortrag NNP cord-015369-72cjogxz 2227 4 wird wird NNP cord-015369-72cjogxz 2227 5 dieser dieser NNP cord-015369-72cjogxz 2228 1 Insellappen Insellappen NNP cord-015369-72cjogxz 2228 2 zur zur NNP cord-015369-72cjogxz 2228 3 Deckung Deckung NNP cord-015369-72cjogxz 2228 4 von von NNP cord-015369-72cjogxz 2228 5 Kinndefekten Kinndefekten NNP cord-015369-72cjogxz 2228 6 vorgestellt vorgestellt NNP cord-015369-72cjogxz 2229 1 und und NNP cord-015369-72cjogxz 2230 1 über über NNP cord-015369-72cjogxz 2230 2 Vor Vor NNP cord-015369-72cjogxz 2230 3 - - HYPH cord-015369-72cjogxz 2230 4 und und NNP cord-015369-72cjogxz 2230 5 Nachteile Nachteile NNP cord-015369-72cjogxz 2230 6 gegenüber gegenüber NNP cord-015369-72cjogxz 2230 7 anderen anderen NNP cord-015369-72cjogxz 2230 8 Rekonstruktionsverfahren Rekonstruktionsverfahren NNP cord-015369-72cjogxz 2230 9 diskutiert diskutiert NNP cord-015369-72cjogxz 2230 10 . . . cord-015369-72cjogxz 2231 1 Methodik Methodik NNP cord-015369-72cjogxz 2231 2 . . . cord-015369-72cjogxz 2232 1 Bei Bei NNP cord-015369-72cjogxz 2232 2 8 8 CD cord-015369-72cjogxz 2233 1 Patienten Patienten NNP cord-015369-72cjogxz 2233 2 mit mit VBP cord-015369-72cjogxz 2233 3 Defekten Defekten NNP cord-015369-72cjogxz 2233 4 des des NNP cord-015369-72cjogxz 2233 5 Untergesichts Untergesichts NNP cord-015369-72cjogxz 2233 6 nach nach NNP cord-015369-72cjogxz 2233 7 ablativer ablativer NNP cord-015369-72cjogxz 2234 1 Tumorchirurgie Tumorchirurgie NNP cord-015369-72cjogxz 2234 2 erfolgte erfolgte NN cord-015369-72cjogxz 2234 3 die die VBP cord-015369-72cjogxz 2234 4 Defektdeckung Defektdeckung NNP cord-015369-72cjogxz 2234 5 mit mit NNP cord-015369-72cjogxz 2234 6 einem einem NNP cord-015369-72cjogxz 2234 7 , , , cord-015369-72cjogxz 2234 8 , , , cord-015369-72cjogxz 2235 1 Sub sub JJ cord-015369-72cjogxz 2235 2 - - JJ cord-015369-72cjogxz 2235 3 mental mental JJ cord-015369-72cjogxz 2235 4 - - HYPH cord-015369-72cjogxz 2235 5 Artery artery NN cord-015369-72cjogxz 2235 6 - - HYPH cord-015369-72cjogxz 2235 7 Perforator Perforator NNP cord-015369-72cjogxz 2235 8 - - HYPH cord-015369-72cjogxz 2235 9 Island Island NNP cord-015369-72cjogxz 2235 10 - - HYPH cord-015369-72cjogxz 2235 11 flap flap NN cord-015369-72cjogxz 2235 12 ' ' '' cord-015369-72cjogxz 2235 13 ' ' '' cord-015369-72cjogxz 2235 14 . . . cord-015369-72cjogxz 2236 1 Sechs Sechs NNP cord-015369-72cjogxz 2236 2 Patienten Patienten NNP cord-015369-72cjogxz 2236 3 zeigten zeigten NN cord-015369-72cjogxz 2236 4 primär primär NN cord-015369-72cjogxz 2237 1 ein ein NNP cord-015369-72cjogxz 2237 2 ausgedehntes ausgedehnte VBZ cord-015369-72cjogxz 2237 3 Basaliom Basaliom NNP cord-015369-72cjogxz 2237 4 der der NNP cord-015369-72cjogxz 2237 5 Kinnregion Kinnregion NNP cord-015369-72cjogxz 2237 6 . . . cord-015369-72cjogxz 2238 1 Nach Nach NNP cord-015369-72cjogxz 2238 2 doppler doppler NNP cord-015369-72cjogxz 2238 3 - - HYPH cord-015369-72cjogxz 2238 4 sonographischer sonographischer JJ cord-015369-72cjogxz 2239 1 Identifikation Identifikation NNP cord-015369-72cjogxz 2239 2 von von NNP cord-015369-72cjogxz 2239 3 ein ein NNP cord-015369-72cjogxz 2239 4 bis bis NNP cord-015369-72cjogxz 2239 5 zwei zwei NNP cord-015369-72cjogxz 2239 6 submentalen submentalen NNP cord-015369-72cjogxz 2239 7 Perforator Perforator NNP cord-015369-72cjogxz 2239 8 - - HYPH cord-015369-72cjogxz 2239 9 Gefäßen Gefäßen NNP cord-015369-72cjogxz 2239 10 erfolgte erfolgte NN cord-015369-72cjogxz 2239 11 die die VB cord-015369-72cjogxz 2239 12 submentale submentale NN cord-015369-72cjogxz 2240 1 Inzision Inzision NNP cord-015369-72cjogxz 2240 2 und und IN cord-015369-72cjogxz 2240 3 Präparation Präparation NNP cord-015369-72cjogxz 2240 4 der der NNP cord-015369-72cjogxz 2240 5 Perforatoren Perforatoren NNP cord-015369-72cjogxz 2241 1 i -PRON- PRP cord-015369-72cjogxz 2241 2 m be VBP cord-015369-72cjogxz 2241 3 Bereich Bereich NNP cord-015369-72cjogxz 2241 4 der der NNP cord-015369-72cjogxz 2241 5 Durchtrittsregion Durchtrittsregion NNP cord-015369-72cjogxz 2241 6 des des FW cord-015369-72cjogxz 2241 7 Musculus Musculus NNP cord-015369-72cjogxz 2241 8 digastricus digastricus NN cord-015369-72cjogxz 2241 9 . . . cord-015369-72cjogxz 2242 1 Der Der NNP cord-015369-72cjogxz 2242 2 Gefäßstiel Gefäßstiel NNP cord-015369-72cjogxz 2242 3 wurde wurde NN cord-015369-72cjogxz 2242 4 bis bis NN cord-015369-72cjogxz 2242 5 zum zum NNP cord-015369-72cjogxz 2242 6 Gefäßursprung Gefäßursprung NNP cord-015369-72cjogxz 2243 1 aus aus NNP cord-015369-72cjogxz 2243 2 der der NNP cord-015369-72cjogxz 2244 1 Arteria Arteria NNP cord-015369-72cjogxz 2244 2 facialis facialis NNP cord-015369-72cjogxz 2244 3 präpariert präpariert NNP cord-015369-72cjogxz 2244 4 und und XX cord-015369-72cjogxz 2245 1 das das NNP cord-015369-72cjogxz 2245 2 Transplantat Transplantat NNP cord-015369-72cjogxz 2245 3 dimensionsgerecht dimensionsgerecht NN cord-015369-72cjogxz 2245 4 gehoben gehoben NN cord-015369-72cjogxz 2245 5 . . . cord-015369-72cjogxz 2246 1 Nach Nach NNP cord-015369-72cjogxz 2246 2 Transposition Transposition NNP cord-015369-72cjogxz 2246 3 in in IN cord-015369-72cjogxz 2246 4 den den NNP cord-015369-72cjogxz 2246 5 Defektbereich Defektbereich NNP cord-015369-72cjogxz 2246 6 wurde wurde NNP cord-015369-72cjogxz 2246 7 der der NNP cord-015369-72cjogxz 2246 8 Haut Haut NNP cord-015369-72cjogxz 2246 9 - - HYPH cord-015369-72cjogxz 2246 10 Fett Fett NNP cord-015369-72cjogxz 2246 11 - - HYPH cord-015369-72cjogxz 2246 12 Lappen Lappen NNP cord-015369-72cjogxz 2246 13 eingenäht eingenäht NN cord-015369-72cjogxz 2247 1 und und NNP cord-015369-72cjogxz 2247 2 die die VB cord-015369-72cjogxz 2248 1 Entnahmeregion Entnahmeregion NNP cord-015369-72cjogxz 2248 2 nach nach NNP cord-015369-72cjogxz 2248 3 lokaler lokaler NNP cord-015369-72cjogxz 2248 4 subkutaner subkutaner NNP cord-015369-72cjogxz 2248 5 Unterminierung Unterminierung NNP cord-015369-72cjogxz 2248 6 direkt direkt NNP cord-015369-72cjogxz 2248 7 verschlossen verschlossen NNP cord-015369-72cjogxz 2248 8 . . . cord-015369-72cjogxz 2249 1 Die die VB cord-015369-72cjogxz 2249 2 klinischen klinischen NNP cord-015369-72cjogxz 2250 1 und und NNP cord-015369-72cjogxz 2251 1 radiologischen radiologischen NNP cord-015369-72cjogxz 2251 2 Nachkontrollen Nachkontrollen NNP cord-015369-72cjogxz 2251 3 erfolgten erfolgten NNP cord-015369-72cjogxz 2251 4 14 14 CD cord-015369-72cjogxz 2251 5 Tage Tage NNP cord-015369-72cjogxz 2251 6 , , , cord-015369-72cjogxz 2251 7 ein ein NNP cord-015369-72cjogxz 2251 8 , , , cord-015369-72cjogxz 2251 9 drei drei NNP cord-015369-72cjogxz 2251 10 , , , cord-015369-72cjogxz 2251 11 sechs sechs NNP cord-015369-72cjogxz 2251 12 und und NNP cord-015369-72cjogxz 2251 13 zwölf zwölf NNP cord-015369-72cjogxz 2251 14 Monate Monate NNP cord-015369-72cjogxz 2251 15 postoperativ postoperativ NNP cord-015369-72cjogxz 2251 16 . . . cord-015369-72cjogxz 2252 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2252 2 . . . cord-015369-72cjogxz 2253 1 Alle Alle NNP cord-015369-72cjogxz 2253 2 Insellappen Insellappen NNP cord-015369-72cjogxz 2253 3 konnten konnten NNP cord-015369-72cjogxz 2253 4 komplikationsfrei komplikationsfrei NN cord-015369-72cjogxz 2253 5 gehoben gehoben NNP cord-015369-72cjogxz 2253 6 werden werden NNP cord-015369-72cjogxz 2253 7 . . . cord-015369-72cjogxz 2254 1 Der Der NNP cord-015369-72cjogxz 2254 2 postoperative postoperative JJ cord-015369-72cjogxz 2254 3 Heilungsverlauf Heilungsverlauf NNP cord-015369-72cjogxz 2254 4 war war NN cord-015369-72cjogxz 2254 5 ebenfalls ebenfalls NN cord-015369-72cjogxz 2254 6 unauffällig unauffällig JJ cord-015369-72cjogxz 2254 7 . . . cord-015369-72cjogxz 2255 1 Alle Alle NNP cord-015369-72cjogxz 2256 1 Patienten Patienten NNP cord-015369-72cjogxz 2256 2 waren waren NNP cord-015369-72cjogxz 2257 1 i -PRON- PRP cord-015369-72cjogxz 2257 2 m be VBP cord-015369-72cjogxz 2257 3 Beobachtungszeitraum Beobachtungszeitraum NNP cord-015369-72cjogxz 2257 4 rezidivfrei rezidivfrei NN cord-015369-72cjogxz 2257 5 . . . cord-015369-72cjogxz 2258 1 Das Das NNP cord-015369-72cjogxz 2258 2 ästhetische ästhetische NNP cord-015369-72cjogxz 2258 3 und und IN cord-015369-72cjogxz 2258 4 funktionelle funktionelle NNP cord-015369-72cjogxz 2259 1 Ergebnis Ergebnis NNP cord-015369-72cjogxz 2259 2 war war NN cord-015369-72cjogxz 2260 1 durchwegs durchwegs NNP cord-015369-72cjogxz 2260 2 zufriedenstellen zufriedenstellen NNP cord-015369-72cjogxz 2260 3 . . . cord-015369-72cjogxz 2261 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 2261 2 . . . cord-015369-72cjogxz 2262 1 Der Der NNP cord-015369-72cjogxz 2263 1 , , , cord-015369-72cjogxz 2263 2 , , , cord-015369-72cjogxz 2263 3 Sub sub JJ cord-015369-72cjogxz 2263 4 - - JJ cord-015369-72cjogxz 2263 5 mental mental JJ cord-015369-72cjogxz 2263 6 - - HYPH cord-015369-72cjogxz 2263 7 Artery artery NN cord-015369-72cjogxz 2263 8 - - HYPH cord-015369-72cjogxz 2263 9 Perforator Perforator NNP cord-015369-72cjogxz 2263 10 - - HYPH cord-015369-72cjogxz 2263 11 Island Island NNP cord-015369-72cjogxz 2263 12 - - HYPH cord-015369-72cjogxz 2263 13 flap flap NN cord-015369-72cjogxz 2263 14 ' ' '' cord-015369-72cjogxz 2263 15 ' ' '' cord-015369-72cjogxz 2263 16 ist ist NN cord-015369-72cjogxz 2263 17 für für NN cord-015369-72cjogxz 2263 18 die die VBP cord-015369-72cjogxz 2264 1 Weichteilrekonstruktion Weichteilrekonstruktion NNP cord-015369-72cjogxz 2265 1 i -PRON- PRP cord-015369-72cjogxz 2265 2 m be VBP cord-015369-72cjogxz 2265 3 Kinnbereich Kinnbereich NNP cord-015369-72cjogxz 2265 4 nach nach NNP cord-015369-72cjogxz 2265 5 Basaliomentfernung Basaliomentfernung NNP cord-015369-72cjogxz 2265 6 gut gut NN cord-015369-72cjogxz 2265 7 geeignet geeignet NNS cord-015369-72cjogxz 2265 8 . . . cord-015369-72cjogxz 2266 1 Die die VB cord-015369-72cjogxz 2266 2 lokalen lokalen NNP cord-015369-72cjogxz 2266 3 Gewebequalitäten Gewebequalitäten NNP cord-015369-72cjogxz 2266 4 paaren paaren NNP cord-015369-72cjogxz 2266 5 sich sich NNP cord-015369-72cjogxz 2266 6 mit mit NNP cord-015369-72cjogxz 2266 7 einer einer NNP cord-015369-72cjogxz 2266 8 weitgehend weitgehend NNP cord-015369-72cjogxz 2266 9 freien freien NNP cord-015369-72cjogxz 2266 10 Transpositionierbarkeit Transpositionierbarkeit NNP cord-015369-72cjogxz 2266 11 des des FW cord-015369-72cjogxz 2266 12 transplantierten transplantierten VBN cord-015369-72cjogxz 2266 13 Gewebes Gewebes NNP cord-015369-72cjogxz 2266 14 . . . cord-015369-72cjogxz 2267 1 Fallbericht Fallbericht NNP cord-015369-72cjogxz 2267 2 . . . cord-015369-72cjogxz 2268 1 Bei Bei NNP cord-015369-72cjogxz 2268 2 einem einem NNP cord-015369-72cjogxz 2269 1 20-jährigen 20-jährigen CD cord-015369-72cjogxz 2269 2 Patienten Patienten NNP cord-015369-72cjogxz 2269 3 bestand bestand NNP cord-015369-72cjogxz 2269 4 ein ein NNP cord-015369-72cjogxz 2269 5 ausgedehnter ausgedehnter NN cord-015369-72cjogxz 2269 6 Defekt Defekt NNP cord-015369-72cjogxz 2269 7 der der NNP cord-015369-72cjogxz 2269 8 Frontobasis Frontobasis NNP cord-015369-72cjogxz 2270 1 und und NNP cord-015369-72cjogxz 2270 2 des des NNP cord-015369-72cjogxz 2270 3 os os NNP cord-015369-72cjogxz 2270 4 frontale frontale NNP cord-015369-72cjogxz 2270 5 betont betont NNP cord-015369-72cjogxz 2270 6 linksseitig linksseitig NNP cord-015369-72cjogxz 2270 7 nach nach NNP cord-015369-72cjogxz 2270 8 Schussverletzung Schussverletzung NNP cord-015369-72cjogxz 2270 9 . . . cord-015369-72cjogxz 2271 1 I -PRON- PRP cord-015369-72cjogxz 2271 2 m be VBP cord-015369-72cjogxz 2271 3 Rahmen Rahmen NNP cord-015369-72cjogxz 2271 4 der der NNP cord-015369-72cjogxz 2271 5 Primärversorgung Primärversorgung NNP cord-015369-72cjogxz 2271 6 erfolgte erfolgte NN cord-015369-72cjogxz 2271 7 eine eine NNP cord-015369-72cjogxz 2271 8 Verplattung Verplattung NNP cord-015369-72cjogxz 2271 9 der der NNP cord-015369-72cjogxz 2271 10 Orbitaringe Orbitaringe NNP cord-015369-72cjogxz 2271 11 , , , cord-015369-72cjogxz 2271 12 Teilentfernung Teilentfernung NNP cord-015369-72cjogxz 2271 13 des des NNP cord-015369-72cjogxz 2271 14 Frontalhirns Frontalhirns NNP cord-015369-72cjogxz 2271 15 , , , cord-015369-72cjogxz 2271 16 eines eines NNP cord-015369-72cjogxz 2271 17 großen großen NNP cord-015369-72cjogxz 2271 18 Anteils Anteils NNP cord-015369-72cjogxz 2271 19 der der NN cord-015369-72cjogxz 2271 20 frontalen frontalen NNP cord-015369-72cjogxz 2271 21 Calvaria Calvaria NNP cord-015369-72cjogxz 2271 22 und und IN cord-015369-72cjogxz 2271 23 ein ein NNP cord-015369-72cjogxz 2271 24 Duradefekt Duradefekt NNP cord-015369-72cjogxz 2271 25 - - HYPH cord-015369-72cjogxz 2271 26 Deckungsversuch Deckungsversuch NNP cord-015369-72cjogxz 2271 27 mit mit XX cord-015369-72cjogxz 2271 28 allogenen allogenen NN cord-015369-72cjogxz 2271 29 Materialien Materialien NNP cord-015369-72cjogxz 2271 30 . . . cord-015369-72cjogxz 2272 1 In in IN cord-015369-72cjogxz 2272 2 der der NNP cord-015369-72cjogxz 2272 3 Folgezeit Folgezeit NNP cord-015369-72cjogxz 2272 4 kam kam NNP cord-015369-72cjogxz 2272 5 es es XX cord-015369-72cjogxz 2272 6 zu zu XX cord-015369-72cjogxz 2272 7 einer einer NNP cord-015369-72cjogxz 2273 1 persistierenden persistierenden NNP cord-015369-72cjogxz 2273 2 Rhinoliquorhoe Rhinoliquorhoe NNP cord-015369-72cjogxz 2273 3 und und IN cord-015369-72cjogxz 2273 4 einer einer NNP cord-015369-72cjogxz 2273 5 Osteomyeltis Osteomyeltis NNP cord-015369-72cjogxz 2273 6 der der VBP cord-015369-72cjogxz 2273 7 refixierten refixierten NNP cord-015369-72cjogxz 2273 8 freien freien NNP cord-015369-72cjogxz 2273 9 Calvariaanteile Calvariaanteile NNP cord-015369-72cjogxz 2273 10 . . . cord-015369-72cjogxz 2274 1 In in IN cord-015369-72cjogxz 2274 2 Kooperation Kooperation NNP cord-015369-72cjogxz 2274 3 mit mit NNP cord-015369-72cjogxz 2274 4 der der NNP cord-015369-72cjogxz 2275 1 Neurochirurgie Neurochirurgie NNP cord-015369-72cjogxz 2275 2 erfolgte erfolgte NNP cord-015369-72cjogxz 2275 3 dann dann NNP cord-015369-72cjogxz 2275 4 die die VB cord-015369-72cjogxz 2275 5 Revision Revision NNP cord-015369-72cjogxz 2275 6 der der NNP cord-015369-72cjogxz 2275 7 Frontobasis Frontobasis NNP cord-015369-72cjogxz 2275 8 . . . cord-015369-72cjogxz 2276 1 Zur Zur NNP cord-015369-72cjogxz 2276 2 Wiederherstellung Wiederherstellung NNP cord-015369-72cjogxz 2276 3 der der NNP cord-015369-72cjogxz 2276 4 Frontobasis Frontobasis NNP cord-015369-72cjogxz 2276 5 und und IN cord-015369-72cjogxz 2276 6 des des NNP cord-015369-72cjogxz 2277 1 Os Os NNP cord-015369-72cjogxz 2277 2 frontale frontale NN cord-015369-72cjogxz 2277 3 wurde wurde NNP cord-015369-72cjogxz 2277 4 ein ein NNP cord-015369-72cjogxz 2277 5 mikrovaskuläres mikrovaskuläres NNP cord-015369-72cjogxz 2277 6 osteoperiostales osteoperiostales NNP cord-015369-72cjogxz 2278 1 Transplantat Transplantat NNP cord-015369-72cjogxz 2278 2 vom vom NNP cord-015369-72cjogxz 2278 3 distalen distalen VBN cord-015369-72cjogxz 2279 1 Femur Femur NNP cord-015369-72cjogxz 2279 2 unter unter NNP cord-015369-72cjogxz 2279 3 Einbeziehung Einbeziehung NNP cord-015369-72cjogxz 2279 4 proximaler proximaler NN cord-015369-72cjogxz 2279 5 Tibiaanteile Tibiaanteile NNP cord-015369-72cjogxz 2279 6 verwendet verwendet NNP cord-015369-72cjogxz 2279 7 . . . cord-015369-72cjogxz 2280 1 Nach Nach NNP cord-015369-72cjogxz 2280 2 der der NNP cord-015369-72cjogxz 2280 3 Angleichung Angleichung NNP cord-015369-72cjogxz 2281 1 an an DT cord-015369-72cjogxz 2281 2 die die NN cord-015369-72cjogxz 2282 1 Defektsituation defektsituation NN cord-015369-72cjogxz 2282 2 wurde wurde NN cord-015369-72cjogxz 2282 3 das das NNP cord-015369-72cjogxz 2282 4 transplantierte transplantierte NNP cord-015369-72cjogxz 2283 1 Periost Periost NNP cord-015369-72cjogxz 2283 2 zur zur NNP cord-015369-72cjogxz 2283 3 basalen basalen NNP cord-015369-72cjogxz 2284 1 Duranarbe Duranarbe NNP cord-015369-72cjogxz 2284 2 und und IN cord-015369-72cjogxz 2284 3 zu zu NNP cord-015369-72cjogxz 2284 4 einem einem NNP cord-015369-72cjogxz 2284 5 lokalen lokalen NNP cord-015369-72cjogxz 2284 6 Calvaria Calvaria NNP cord-015369-72cjogxz 2284 7 . . . cord-015369-72cjogxz 2285 1 Perioslappen Perioslappen NNP cord-015369-72cjogxz 2285 2 vernäht vernäht NNP cord-015369-72cjogxz 2285 3 und und IN cord-015369-72cjogxz 2285 4 mit mit NNP cord-015369-72cjogxz 2285 5 Miniplatten Miniplatten NNP cord-015369-72cjogxz 2285 6 zur zur NNP cord-015369-72cjogxz 2285 7 übrigen übrigen NNP cord-015369-72cjogxz 2285 8 Calvaria Calvaria NNP cord-015369-72cjogxz 2285 9 fixiert fixiert NNP cord-015369-72cjogxz 2285 10 . . . cord-015369-72cjogxz 2286 1 Danach Danach NNP cord-015369-72cjogxz 2286 2 wurde wurde NN cord-015369-72cjogxz 2286 3 der der NNP cord-015369-72cjogxz 2286 4 Transplantatstiel Transplantatstiel NNP cord-015369-72cjogxz 2286 5 mit mit NNP cord-015369-72cjogxz 2286 6 der der NNP cord-015369-72cjogxz 2286 7 zur zur NNP cord-015369-72cjogxz 2286 8 Arteria Arteria NNP cord-015369-72cjogxz 2286 9 und und XX cord-015369-72cjogxz 2287 1 Vena Vena NNP cord-015369-72cjogxz 2287 2 temporalis temporalis NNP cord-015369-72cjogxz 2287 3 superficialis superficialis NNP cord-015369-72cjogxz 2288 1 anastomosiert anastomosiert JJ cord-015369-72cjogxz 2288 2 und und NNP cord-015369-72cjogxz 2288 3 der der NN cord-015369-72cjogxz 2288 4 Wundschluss Wundschluss NNP cord-015369-72cjogxz 2288 5 durchgeführt durchgeführt NN cord-015369-72cjogxz 2288 6 . . . cord-015369-72cjogxz 2289 1 In in IN cord-015369-72cjogxz 2289 2 einem einem NNP cord-015369-72cjogxz 2289 3 Nachbeobachtungszeitraum Nachbeobachtungszeitraum NNP cord-015369-72cjogxz 2289 4 von von NNP cord-015369-72cjogxz 2289 5 8 8 CD cord-015369-72cjogxz 2289 6 Monaten Monaten NNP cord-015369-72cjogxz 2289 7 kam kam NNP cord-015369-72cjogxz 2289 8 es es XX cord-015369-72cjogxz 2289 9 zu zu NNP cord-015369-72cjogxz 2289 10 keiner keiner NNP cord-015369-72cjogxz 2289 11 erneuten erneuten NNP cord-015369-72cjogxz 2289 12 Liquoroe Liquoroe NNP cord-015369-72cjogxz 2289 13 oder oder NN cord-015369-72cjogxz 2289 14 Infektion Infektion NNP cord-015369-72cjogxz 2289 15 dieser dieser NNP cord-015369-72cjogxz 2289 16 Region Region NNP cord-015369-72cjogxz 2289 17 . . . cord-015369-72cjogxz 2290 1 Es Es NNP cord-015369-72cjogxz 2290 2 konnte konnte NNP cord-015369-72cjogxz 2291 1 eine eine NNP cord-015369-72cjogxz 2291 2 wesentliche wesentliche NNP cord-015369-72cjogxz 2291 3 Verbesserung Verbesserung NNP cord-015369-72cjogxz 2291 4 der der NNP cord-015369-72cjogxz 2291 5 Schädelform Schädelform NNP cord-015369-72cjogxz 2291 6 erzielt erzielt NNS cord-015369-72cjogxz 2291 7 werden werden NNS cord-015369-72cjogxz 2291 8 . . . cord-015369-72cjogxz 2292 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 2292 2 . . . cord-015369-72cjogxz 2293 1 Das Das NNP cord-015369-72cjogxz 2293 2 mikrovaskuläre mikrovaskuläre NNP cord-015369-72cjogxz 2293 3 osteoperiostale osteoperiostale NNP cord-015369-72cjogxz 2294 1 Femurtransplantat Femurtransplantat NNP cord-015369-72cjogxz 2294 2 kann kann NNP cord-015369-72cjogxz 2294 3 unter unter NNP cord-015369-72cjogxz 2294 4 besonderen besonderen NNP cord-015369-72cjogxz 2295 1 Bedingungen Bedingungen NNP cord-015369-72cjogxz 2295 2 durch durch NNP cord-015369-72cjogxz 2295 3 die die VBP cord-015369-72cjogxz 2295 4 Miteinbeziehung Miteinbeziehung NNP cord-015369-72cjogxz 2295 5 distaler distaler NN cord-015369-72cjogxz 2296 1 Tibiaanteile Tibiaanteile NNP cord-015369-72cjogxz 2296 2 extendiert extendiert JJ cord-015369-72cjogxz 2296 3 werden werden NNP cord-015369-72cjogxz 2296 4 . . . cord-015369-72cjogxz 2297 1 Die die VB cord-015369-72cjogxz 2297 2 Gefäßversorgung Gefäßversorgung NNP cord-015369-72cjogxz 2297 3 über über NNP cord-015369-72cjogxz 2297 4 das das NNP cord-015369-72cjogxz 2297 5 Rete Rete NNP cord-015369-72cjogxz 2297 6 articularis articularis NN cord-015369-72cjogxz 2297 7 gewährleistet gewährleistet NNP cord-015369-72cjogxz 2297 8 eine eine NNP cord-015369-72cjogxz 2297 9 gute gute NNP cord-015369-72cjogxz 2297 10 Perfusion Perfusion NNP cord-015369-72cjogxz 2297 11 des des FW cord-015369-72cjogxz 2297 12 medialen medialen NNP cord-015369-72cjogxz 2297 13 proximalen proximalen NNP cord-015369-72cjogxz 2297 14 Tibiaperiosts Tibiaperiosts NNPS cord-015369-72cjogxz 2297 15 . . . cord-015369-72cjogxz 2298 1 Das Das NNP cord-015369-72cjogxz 2298 2 Transplantat Transplantat NNP cord-015369-72cjogxz 2298 3 ist ist NNP cord-015369-72cjogxz 2298 4 somit somit NN cord-015369-72cjogxz 2298 5 für für VBP cord-015369-72cjogxz 2298 6 die die VBP cord-015369-72cjogxz 2298 7 Deckung Deckung NNP cord-015369-72cjogxz 2298 8 ausgedehnter ausgedehnter NN cord-015369-72cjogxz 2298 9 Calvariadefekte Calvariadefekte NNP cord-015369-72cjogxz 2298 10 geeignet geeignet NNP cord-015369-72cjogxz 2298 11 . . . cord-015369-72cjogxz 2299 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 2299 2 . . . cord-015369-72cjogxz 2300 1 Die die VB cord-015369-72cjogxz 2300 2 Therapie Therapie NNP cord-015369-72cjogxz 2300 3 von von NNP cord-015369-72cjogxz 2300 4 Patienten Patienten NNP cord-015369-72cjogxz 2300 5 mit mit NNP cord-015369-72cjogxz 2300 6 Lippen Lippen NNP cord-015369-72cjogxz 2300 7 - - HYPH cord-015369-72cjogxz 2300 8 Kiefer Kiefer NNP cord-015369-72cjogxz 2300 9 - - HYPH cord-015369-72cjogxz 2300 10 Gaumenspalten Gaumenspalten NNP cord-015369-72cjogxz 2300 11 birgt birgt NN cord-015369-72cjogxz 2301 1 fü fü IN cord-015369-72cjogxz 2301 2 r r DT cord-015369-72cjogxz 2301 3 Chirurgen Chirurgen NNP cord-015369-72cjogxz 2301 4 und und XX cord-015369-72cjogxz 2302 1 Kieferorthopäden Kieferorthopäden NNP cord-015369-72cjogxz 2302 2 große große NNP cord-015369-72cjogxz 2302 3 Herausforderungen Herausforderungen NNP cord-015369-72cjogxz 2302 4 . . . cord-015369-72cjogxz 2303 1 Einerseits Einerseits NNP cord-015369-72cjogxz 2303 2 zeigt zeigt NNP cord-015369-72cjogxz 2303 3 sich sich NNP cord-015369-72cjogxz 2303 4 häufig häufig NNP cord-015369-72cjogxz 2303 5 operationsnarben operationsnarben NN cord-015369-72cjogxz 2303 6 bedingt bedingt NNP cord-015369-72cjogxz 2303 7 ein ein NNP cord-015369-72cjogxz 2303 8 eingeschränktes eingeschränkte VBZ cord-015369-72cjogxz 2303 9 sagittales sagittales NNP cord-015369-72cjogxz 2303 10 wie wie NNP cord-015369-72cjogxz 2303 11 transversales transversales NNPS cord-015369-72cjogxz 2303 12 Oberkieferwachstum Oberkieferwachstum NNP cord-015369-72cjogxz 2303 13 , , , cord-015369-72cjogxz 2304 1 andererseits andererseits NNP cord-015369-72cjogxz 2304 2 erschweren erschweren NNP cord-015369-72cjogxz 2304 3 Zahnnichtanlagen Zahnnichtanlagen NNP cord-015369-72cjogxz 2304 4 , , , cord-015369-72cjogxz 2304 5 sowie sowie NNP cord-015369-72cjogxz 2304 6 das das NNP cord-015369-72cjogxz 2304 7 Fehlen Fehlen NNP cord-015369-72cjogxz 2304 8 von von NNP cord-015369-72cjogxz 2304 9 Knochen Knochen NNP cord-015369-72cjogxz 2305 1 i -PRON- PRP cord-015369-72cjogxz 2305 2 m be VBP cord-015369-72cjogxz 2305 3 Kieferspaltenbereich Kieferspaltenbereich NNP cord-015369-72cjogxz 2305 4 das das XX cord-015369-72cjogxz 2305 5 therapeutische therapeutische IN cord-015369-72cjogxz 2305 6 Vorgehen Vorgehen NNP cord-015369-72cjogxz 2305 7 . . . cord-015369-72cjogxz 2306 1 Segmentosteotomien Segmentosteotomien NNP cord-015369-72cjogxz 2306 2 sind sind NNP cord-015369-72cjogxz 2307 1 eine eine NNP cord-015369-72cjogxz 2307 2 erprobte erprobte NNP cord-015369-72cjogxz 2307 3 Methode Methode NNP cord-015369-72cjogxz 2307 4 in in IN cord-015369-72cjogxz 2307 5 der der NNP cord-015369-72cjogxz 2307 6 Behandlung Behandlung NNP cord-015369-72cjogxz 2307 7 von von NNP cord-015369-72cjogxz 2307 8 Dysgnathien Dysgnathien NNP cord-015369-72cjogxz 2307 9 , , , cord-015369-72cjogxz 2308 1 sowie sowie NNP cord-015369-72cjogxz 2308 2 Zahnfehlstellungen Zahnfehlstellungen NNP cord-015369-72cjogxz 2308 3 können können NNP cord-015369-72cjogxz 2308 4 aber aber NNP cord-015369-72cjogxz 2308 5 nur nur NNP cord-015369-72cjogxz 2308 6 eingeschränkt eingeschränkt NNP cord-015369-72cjogxz 2308 7 beim beim NNP cord-015369-72cjogxz 2308 8 wachsenden wachsenden NNP cord-015369-72cjogxz 2309 1 Kind kind JJ cord-015369-72cjogxz 2309 2 zum zum NNP cord-015369-72cjogxz 2309 3 Einsatz Einsatz NNP cord-015369-72cjogxz 2309 4 kommen kommen NNP cord-015369-72cjogxz 2309 5 . . . cord-015369-72cjogxz 2310 1 Segmentdistraktion Segmentdistraktion NNP cord-015369-72cjogxz 2310 2 erlaubt erlaubt NNP cord-015369-72cjogxz 2310 3 eine eine NNP cord-015369-72cjogxz 2310 4 entsprechende entsprechende NNP cord-015369-72cjogxz 2310 5 Therapie Therapie NNP cord-015369-72cjogxz 2311 1 auch auch NNP cord-015369-72cjogxz 2311 2 beim beim NNP cord-015369-72cjogxz 2311 3 wachsenden wachsenden NNP cord-015369-72cjogxz 2311 4 Kind Kind NNP cord-015369-72cjogxz 2311 5 . . . cord-015369-72cjogxz 2312 1 Methodik Methodik NNP cord-015369-72cjogxz 2312 2 . . . cord-015369-72cjogxz 2313 1 5 5 LS cord-015369-72cjogxz 2314 1 Kinder Kinder NNP cord-015369-72cjogxz 2314 2 mit mit NNP cord-015369-72cjogxz 2314 3 kompletten kompletten NNP cord-015369-72cjogxz 2315 1 Lippen Lippen NNP cord-015369-72cjogxz 2315 2 - - HYPH cord-015369-72cjogxz 2315 3 Kiefer Kiefer NNP cord-015369-72cjogxz 2315 4 - - HYPH cord-015369-72cjogxz 2315 5 Gaumenspalten Gaumenspalten NNP cord-015369-72cjogxz 2315 6 wurden wurden VBD cord-015369-72cjogxz 2315 7 untersucht untersucht FW cord-015369-72cjogxz 2315 8 . . . cord-015369-72cjogxz 2316 1 Alle Alle NNP cord-015369-72cjogxz 2316 2 Kinder Kinder NNP cord-015369-72cjogxz 2316 3 zeigten zeigten XX cord-015369-72cjogxz 2316 4 sehr sehr NNP cord-015369-72cjogxz 2316 5 breite breite NNP cord-015369-72cjogxz 2317 1 Kieferspalten Kieferspalten NNP cord-015369-72cjogxz 2317 2 mit mit NNP cord-015369-72cjogxz 2317 3 zum zum NNP cord-015369-72cjogxz 2317 4 Teil Teil NNP cord-015369-72cjogxz 2317 5 multiplen multiplen NN cord-015369-72cjogxz 2317 6 Zahnnichtanlagen Zahnnichtanlagen NNP cord-015369-72cjogxz 2317 7 . . . cord-015369-72cjogxz 2318 1 Zum Zum NNP cord-015369-72cjogxz 2318 2 Schluss Schluss NNP cord-015369-72cjogxz 2318 3 der der NNP cord-015369-72cjogxz 2318 4 Kieferspalten Kieferspalten NNP cord-015369-72cjogxz 2318 5 wurden wurden NNS cord-015369-72cjogxz 2318 6 die die VBP cord-015369-72cjogxz 2318 7 spaltfernen spaltfernen NNP cord-015369-72cjogxz 2318 8 Segmente Segmente NNP cord-015369-72cjogxz 2318 9 osteotomiert osteotomiert NN cord-015369-72cjogxz 2318 10 und und NNP cord-015369-72cjogxz 2318 11 mittels mittels NNP cord-015369-72cjogxz 2318 12 individuell individuell NNP cord-015369-72cjogxz 2318 13 angefertigter angefertigter NNP cord-015369-72cjogxz 2318 14 Distraktoren Distraktoren NNP cord-015369-72cjogxz 2318 15 mesialisiert mesialisiert NNP cord-015369-72cjogxz 2318 16 . . . cord-015369-72cjogxz 2319 1 Am be VBP cord-015369-72cjogxz 2319 2 fünften fünften VBN cord-015369-72cjogxz 2319 3 postoperativen postoperativen VBN cord-015369-72cjogxz 2319 4 Tag tag NN cord-015369-72cjogxz 2319 5 wurde wurde NNP cord-015369-72cjogxz 2319 6 mit mit NNP cord-015369-72cjogxz 2319 7 der der NNP cord-015369-72cjogxz 2319 8 Distraktion Distraktion NNP cord-015369-72cjogxz 2319 9 von von NNP cord-015369-72cjogxz 2319 10 1 1 CD cord-015369-72cjogxz 2319 11 mm mm NNP cord-015369-72cjogxz 2319 12 pro pro JJ cord-015369-72cjogxz 2319 13 Tag tag NN cord-015369-72cjogxz 2319 14 begonnen begonnen FW cord-015369-72cjogxz 2319 15 . . . cord-015369-72cjogxz 2320 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2320 2 . . . cord-015369-72cjogxz 2321 1 Bis Bis NNP cord-015369-72cjogxz 2321 2 dato dato NNP cord-015369-72cjogxz 2321 3 ist ist NNP cord-015369-72cjogxz 2321 4 die die VBP cord-015369-72cjogxz 2321 5 kieferchirurgisch kieferchirurgisch NNP cord-015369-72cjogxz 2321 6 / / SYM cord-015369-72cjogxz 2321 7 kieferorthopädische kieferorthopädische NNP cord-015369-72cjogxz 2321 8 Therpie Therpie NNP cord-015369-72cjogxz 2321 9 bei bei NNP cord-015369-72cjogxz 2321 10 zwei zwei NNP cord-015369-72cjogxz 2321 11 Patienten Patienten NNP cord-015369-72cjogxz 2321 12 abgeschlossen abgeschlossen NNP cord-015369-72cjogxz 2321 13 . . . cord-015369-72cjogxz 2322 1 Bei Bei NNP cord-015369-72cjogxz 2322 2 drei drei NNP cord-015369-72cjogxz 2323 1 Patienten Patienten NNP cord-015369-72cjogxz 2323 2 ist ist NN cord-015369-72cjogxz 2323 3 die die VBP cord-015369-72cjogxz 2323 4 Distraktionsphase Distraktionsphase NNP cord-015369-72cjogxz 2323 5 abgeschlossen abgeschlossen NN cord-015369-72cjogxz 2323 6 , , , cord-015369-72cjogxz 2323 7 nicht nicht NNP cord-015369-72cjogxz 2323 8 aber aber NNP cord-015369-72cjogxz 2323 9 die die VBP cord-015369-72cjogxz 2323 10 Kieferorthopädie Kieferorthopädie NNP cord-015369-72cjogxz 2323 11 . . . cord-015369-72cjogxz 2324 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 2324 2 . . . cord-015369-72cjogxz 2325 1 Segmentdistraktionen Segmentdistraktionen NNP cord-015369-72cjogxz 2325 2 sind sind IN cord-015369-72cjogxz 2325 3 ein ein NN cord-015369-72cjogxz 2325 4 probates probate NNS cord-015369-72cjogxz 2325 5 Mittel Mittel NNP cord-015369-72cjogxz 2325 6 zum zum NNP cord-015369-72cjogxz 2325 7 Lückenschluss Lückenschluss NNP cord-015369-72cjogxz 2325 8 bei bei NNP cord-015369-72cjogxz 2325 9 Spaltpatienten Spaltpatienten NNP cord-015369-72cjogxz 2325 10 mit mit NNP cord-015369-72cjogxz 2325 11 ausgedehnten ausgedehnten NNP cord-015369-72cjogxz 2326 1 Kieferspalten Kieferspalten NNP cord-015369-72cjogxz 2326 2 , , , cord-015369-72cjogxz 2326 3 sowie sowie NNP cord-015369-72cjogxz 2326 4 Nichtanlagen Nichtanlagen NNP cord-015369-72cjogxz 2326 5 . . . cord-015369-72cjogxz 2327 1 Der Der NNP cord-015369-72cjogxz 2327 2 Vorteil Vorteil NNP cord-015369-72cjogxz 2327 3 der der NNP cord-015369-72cjogxz 2327 4 Distraktion Distraktion NNP cord-015369-72cjogxz 2327 5 ist ist NN cord-015369-72cjogxz 2327 6 , , , cord-015369-72cjogxz 2327 7 dass dass NNP cord-015369-72cjogxz 2327 8 die die VBP cord-015369-72cjogxz 2327 9 Therapie Therapie NNP cord-015369-72cjogxz 2327 10 während während NNP cord-015369-72cjogxz 2327 11 des des NNP cord-015369-72cjogxz 2327 12 Wachstums Wachstums NNP cord-015369-72cjogxz 2327 13 durchgeführt durchgeführt NN cord-015369-72cjogxz 2327 14 werden werden NNP cord-015369-72cjogxz 2327 15 kann kann NNP cord-015369-72cjogxz 2327 16 . . . cord-015369-72cjogxz 2328 1 Die die VB cord-015369-72cjogxz 2328 2 ersten ersten NNP cord-015369-72cjogxz 2328 3 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2328 4 der der NNP cord-015369-72cjogxz 2328 5 durchgeführten durchgeführten NNP cord-015369-72cjogxz 2329 1 Segmentdistraktionen Segmentdistraktionen NNP cord-015369-72cjogxz 2329 2 bei bei NNP cord-015369-72cjogxz 2329 3 Patienten Patienten NNP cord-015369-72cjogxz 2329 4 mit mit VBP cord-015369-72cjogxz 2329 5 kompletten kompletten NNP cord-015369-72cjogxz 2329 6 Lippen Lippen NNP cord-015369-72cjogxz 2329 7 - - HYPH cord-015369-72cjogxz 2329 8 Kiefer Kiefer NNP cord-015369-72cjogxz 2329 9 - - HYPH cord-015369-72cjogxz 2329 10 Gaumenspalten Gaumenspalten NNP cord-015369-72cjogxz 2329 11 sollen sollen NNP cord-015369-72cjogxz 2329 12 präsentiert präsentiert NNP cord-015369-72cjogxz 2329 13 werden werden NNP cord-015369-72cjogxz 2329 14 . . . cord-015369-72cjogxz 2330 1 Is be VBZ cord-015369-72cjogxz 2330 2 a a DT cord-015369-72cjogxz 2330 3 SARME SARME NNP cord-015369-72cjogxz 2330 4 possible possible JJ cord-015369-72cjogxz 2330 5 without without IN cord-015369-72cjogxz 2330 6 detachement detachement NN cord-015369-72cjogxz 2330 7 of of IN cord-015369-72cjogxz 2330 8 nasal nasal NN cord-015369-72cjogxz 2330 9 septum septum NN cord-015369-72cjogxz 2330 10 ? ? . cord-015369-72cjogxz 2331 1 Abteilung Abteilung NNP cord-015369-72cjogxz 2331 2 Mund- Mund- NNP cord-015369-72cjogxz 2331 3 , , , cord-015369-72cjogxz 2331 4 Kiefer Kiefer NNP cord-015369-72cjogxz 2331 5 und und IN cord-015369-72cjogxz 2331 6 Gesichtschirurgie Gesichtschirurgie NNP cord-015369-72cjogxz 2331 7 , , , cord-015369-72cjogxz 2331 8 Graz Graz NNP cord-015369-72cjogxz 2331 9 , , , cord-015369-72cjogxz 2331 10 Austria Austria NNP cord-015369-72cjogxz 2331 11 Objectives Objectives NNP cord-015369-72cjogxz 2331 12 . . . cord-015369-72cjogxz 2332 1 Die die VB cord-015369-72cjogxz 2332 2 chirurgische chirurgische NN cord-015369-72cjogxz 2333 1 Gaumennahterweiterung Gaumennahterweiterung NNP cord-015369-72cjogxz 2333 2 ist ist NNP cord-015369-72cjogxz 2334 1 ein ein NNP cord-015369-72cjogxz 2334 2 bewährter bewährter NN cord-015369-72cjogxz 2334 3 Eingriff Eingriff NNP cord-015369-72cjogxz 2334 4 zur zur NNP cord-015369-72cjogxz 2334 5 Lösung Lösung NNP cord-015369-72cjogxz 2334 6 der der NNP cord-015369-72cjogxz 2334 7 sutura sutura NNP cord-015369-72cjogxz 2334 8 palatina palatina NNP cord-015369-72cjogxz 2335 1 mediana mediana NNP cord-015369-72cjogxz 2335 2 bei bei NNP cord-015369-72cjogxz 2335 3 einer einer NNP cord-015369-72cjogxz 2335 4 transversalen transversalen NNP cord-015369-72cjogxz 2335 5 Größendiskrepanz Größendiskrepanz NNP cord-015369-72cjogxz 2335 6 der der NNP cord-015369-72cjogxz 2335 7 Kiefer Kiefer NNP cord-015369-72cjogxz 2335 8 . . . cord-015369-72cjogxz 2336 1 Ziel Ziel NNP cord-015369-72cjogxz 2336 2 der der NNP cord-015369-72cjogxz 2336 3 Untersuchung Untersuchung NNP cord-015369-72cjogxz 2336 4 war war NN cord-015369-72cjogxz 2336 5 die die VBP cord-015369-72cjogxz 2336 6 Evaluierung Evaluierung NNP cord-015369-72cjogxz 2336 7 einer einer NNP cord-015369-72cjogxz 2336 8 möglichen möglichen NNP cord-015369-72cjogxz 2337 1 Bewegung Bewegung NNP cord-015369-72cjogxz 2337 2 des des NNP cord-015369-72cjogxz 2337 3 Nasenseptums Nasenseptums NNP cord-015369-72cjogxz 2338 1 i -PRON- PRP cord-015369-72cjogxz 2338 2 m be VBP cord-015369-72cjogxz 2338 3 Rahmen Rahmen NNP cord-015369-72cjogxz 2339 1 einer einer NNP cord-015369-72cjogxz 2339 2 chirurgischen chirurgischen NNP cord-015369-72cjogxz 2339 3 Gaumennahterweiterung Gaumennahterweiterung NNP cord-015369-72cjogxz 2339 4 . . . cord-015369-72cjogxz 2340 1 Study study NN cord-015369-72cjogxz 2340 2 design design NN cord-015369-72cjogxz 2340 3 . . . cord-015369-72cjogxz 2341 1 Der Der NNP cord-015369-72cjogxz 2341 2 chirurgische chirurgische NN cord-015369-72cjogxz 2341 3 Eingriff eingriff NN cord-015369-72cjogxz 2342 1 wurde wurde NNP cord-015369-72cjogxz 2342 2 als als NNP cord-015369-72cjogxz 2342 3 laterale laterale NNP cord-015369-72cjogxz 2343 1 Osteotomie Osteotomie NNP cord-015369-72cjogxz 2344 1 und und NNP cord-015369-72cjogxz 2344 2 mediane mediane NNP cord-015369-72cjogxz 2344 3 Osteotomie Osteotomie NNP cord-015369-72cjogxz 2344 4 ohne ohne NNP cord-015369-72cjogxz 2344 5 Lösung Lösung NNP cord-015369-72cjogxz 2344 6 des des FW cord-015369-72cjogxz 2344 7 Septum Septum NNP cord-015369-72cjogxz 2344 8 nasi nasi NN cord-015369-72cjogxz 2344 9 durchgeführt durchgeführt NN cord-015369-72cjogxz 2344 10 . . . cord-015369-72cjogxz 2345 1 Anhand Anhand NNP cord-015369-72cjogxz 2345 2 von von NNP cord-015369-72cjogxz 2345 3 gewählten gewählten NNP cord-015369-72cjogxz 2346 1 radiologischen radiologischen NNP cord-015369-72cjogxz 2346 2 Referenzpunkten Referenzpunkten NNP cord-015369-72cjogxz 2346 3 wurde wurde NNP cord-015369-72cjogxz 2346 4 die die VBP cord-015369-72cjogxz 2347 1 Position Position NNP cord-015369-72cjogxz 2347 2 des des FW cord-015369-72cjogxz 2347 3 Nasenseptums Nasenseptums NNP cord-015369-72cjogxz 2348 1 i -PRON- PRP cord-015369-72cjogxz 2348 2 m be VBP cord-015369-72cjogxz 2349 1 prä prä UH cord-015369-72cjogxz 2349 2 - - HYPH cord-015369-72cjogxz 2349 3 und und NNP cord-015369-72cjogxz 2349 4 postoperative postoperative JJ cord-015369-72cjogxz 2349 5 CT CT NNP cord-015369-72cjogxz 2349 6 vermessen vermessen NNP cord-015369-72cjogxz 2349 7 und und IN cord-015369-72cjogxz 2349 8 mögliche mögliche NNP cord-015369-72cjogxz 2349 9 Abweichungen Abweichungen NNP cord-015369-72cjogxz 2349 10 erfasst erfasst NNP cord-015369-72cjogxz 2349 11 . . . cord-015369-72cjogxz 2350 1 Conclusions conclusion NNS cord-015369-72cjogxz 2350 2 . . . cord-015369-72cjogxz 2351 1 Bei Bei NNP cord-015369-72cjogxz 2351 2 einer einer NNP cord-015369-72cjogxz 2352 1 durchschnittlichen durchschnittlichen NNP cord-015369-72cjogxz 2353 1 Erweiterung Erweiterung NNP cord-015369-72cjogxz 2353 2 von von NNP cord-015369-72cjogxz 2354 1 4 4 CD cord-015369-72cjogxz 2354 2 mm mm NN cord-015369-72cjogxz 2355 1 wurde wurde NNP cord-015369-72cjogxz 2355 2 einer einer NNP cord-015369-72cjogxz 2355 3 Winkeldifferenz Winkeldifferenz NNP cord-015369-72cjogxz 2355 4 von von NNP cord-015369-72cjogxz 2355 5 3,3 3,3 CD cord-015369-72cjogxz 2356 1 zwischen zwischen NNP cord-015369-72cjogxz 2356 2 sagittaler sagittaler NNP cord-015369-72cjogxz 2356 3 und und IN cord-015369-72cjogxz 2356 4 axialer axialer NNP cord-015369-72cjogxz 2356 5 Ebenen Ebenen NNP cord-015369-72cjogxz 2356 6 gemessen gemessen NNP cord-015369-72cjogxz 2356 7 . . . cord-015369-72cjogxz 2357 1 Die die VB cord-015369-72cjogxz 2357 2 sagittalen sagittalen NNP cord-015369-72cjogxz 2357 3 Ebenen Ebenen NNP cord-015369-72cjogxz 2357 4 erfahren erfahren NNP cord-015369-72cjogxz 2357 5 eine eine NNP cord-015369-72cjogxz 2357 6 Abweichung Abweichung NNP cord-015369-72cjogxz 2357 7 von von NNP cord-015369-72cjogxz 2357 8 1 1 CD cord-015369-72cjogxz 2357 9 . . . cord-015369-72cjogxz 2358 1 Die die VB cord-015369-72cjogxz 2358 2 nasalen nasalen NNP cord-015369-72cjogxz 2358 3 Atemwege Atemwege NNP cord-015369-72cjogxz 2358 4 zeigen zeigen NNP cord-015369-72cjogxz 2359 1 eine eine NNP cord-015369-72cjogxz 2359 2 Zunahme Zunahme NNP cord-015369-72cjogxz 2360 1 an an DT cord-015369-72cjogxz 2360 2 Volumen Volumen NNP cord-015369-72cjogxz 2360 3 , , , cord-015369-72cjogxz 2360 4 ohne ohne NNP cord-015369-72cjogxz 2360 5 eine eine NNP cord-015369-72cjogxz 2360 6 signifikante signifikante NNP cord-015369-72cjogxz 2360 7 Ä Ä NNP cord-015369-72cjogxz 2360 8 nderung nderung NNP cord-015369-72cjogxz 2360 9 der der NNP cord-015369-72cjogxz 2360 10 anatomischen anatomischen NNP cord-015369-72cjogxz 2360 11 Gegebenheiten Gegebenheiten NNP cord-015369-72cjogxz 2360 12 , , , cord-015369-72cjogxz 2360 13 so so RB cord-015369-72cjogxz 2360 14 erweist erweist NNP cord-015369-72cjogxz 2360 15 sich sich NNP cord-015369-72cjogxz 2360 16 die die VB cord-015369-72cjogxz 2361 1 chirurgische chirurgische NNP cord-015369-72cjogxz 2361 2 Gaumennahterweiterung Gaumennahterweiterung NNP cord-015369-72cjogxz 2361 3 als als NN cord-015369-72cjogxz 2361 4 suffizienter suffizienter NN cord-015369-72cjogxz 2361 5 Eingriff eingriff NN cord-015369-72cjogxz 2361 6 . . . cord-015369-72cjogxz 2362 1 Using use VBG cord-015369-72cjogxz 2362 2 Bisphosphonates Bisphosphonates NNP cord-015369-72cjogxz 2362 3 in in IN cord-015369-72cjogxz 2362 4 the the DT cord-015369-72cjogxz 2362 5 treatment treatment NN cord-015369-72cjogxz 2362 6 and and CC cord-015369-72cjogxz 2362 7 management management NN cord-015369-72cjogxz 2362 8 of of IN cord-015369-72cjogxz 2362 9 systematic systematic JJ cord-015369-72cjogxz 2362 10 illnesses illness NNS cord-015369-72cjogxz 2362 11 e.g. e.g. IN cord-015369-72cjogxz 2362 12 plasmocytom plasmocytom NNS cord-015369-72cjogxz 2362 13 and and CC cord-015369-72cjogxz 2362 14 metastasizing metastasize VBG cord-015369-72cjogxz 2362 15 illnesses illness NNS cord-015369-72cjogxz 2362 16 is be VBZ cord-015369-72cjogxz 2362 17 undisputed undisputed JJ cord-015369-72cjogxz 2362 18 . . . cord-015369-72cjogxz 2363 1 However however RB cord-015369-72cjogxz 2363 2 one one CD cord-015369-72cjogxz 2363 3 of of IN cord-015369-72cjogxz 2363 4 the the DT cord-015369-72cjogxz 2363 5 most most RBS cord-015369-72cjogxz 2363 6 feared fear VBN cord-015369-72cjogxz 2363 7 side side NN cord-015369-72cjogxz 2363 8 effects effect NNS cord-015369-72cjogxz 2363 9 of of IN cord-015369-72cjogxz 2363 10 this this DT cord-015369-72cjogxz 2363 11 systemic systemic JJ cord-015369-72cjogxz 2363 12 therapy therapy NN cord-015369-72cjogxz 2363 13 is be VBZ cord-015369-72cjogxz 2363 14 osteonecrosis osteonecrosis NN cord-015369-72cjogxz 2363 15 of of IN cord-015369-72cjogxz 2363 16 the the DT cord-015369-72cjogxz 2363 17 jaw jaw NN cord-015369-72cjogxz 2363 18 . . . cord-015369-72cjogxz 2364 1 Estimates estimate NNS cord-015369-72cjogxz 2364 2 of of IN cord-015369-72cjogxz 2364 3 the the DT cord-015369-72cjogxz 2364 4 cumulative cumulative JJ cord-015369-72cjogxz 2364 5 incidence incidence NN cord-015369-72cjogxz 2364 6 of of IN cord-015369-72cjogxz 2364 7 BRONJ bronj NN cord-015369-72cjogxz 2364 8 range range NN cord-015369-72cjogxz 2364 9 from from IN cord-015369-72cjogxz 2364 10 0.8 0.8 CD cord-015369-72cjogxz 2364 11 - - SYM cord-015369-72cjogxz 2364 12 12 12 CD cord-015369-72cjogxz 2364 13 % % NN cord-015369-72cjogxz 2364 14 . . . cord-015369-72cjogxz 2365 1 With with IN cord-015369-72cjogxz 2365 2 increased increase VBN cord-015369-72cjogxz 2365 3 recognition recognition NN cord-015369-72cjogxz 2365 4 , , , cord-015369-72cjogxz 2365 5 duration duration NN cord-015369-72cjogxz 2365 6 of of IN cord-015369-72cjogxz 2365 7 exposure exposure NN cord-015369-72cjogxz 2365 8 , , , cord-015369-72cjogxz 2365 9 and and CC cord-015369-72cjogxz 2365 10 follow follow NN cord-015369-72cjogxz 2365 11 - - HYPH cord-015369-72cjogxz 2365 12 up up NN cord-015369-72cjogxz 2365 13 , , , cord-015369-72cjogxz 2365 14 it -PRON- PRP cord-015369-72cjogxz 2365 15 is be VBZ cord-015369-72cjogxz 2365 16 likely likely JJ cord-015369-72cjogxz 2365 17 that that IN cord-015369-72cjogxz 2365 18 the the DT cord-015369-72cjogxz 2365 19 incidence incidence NN cord-015369-72cjogxz 2365 20 will will MD cord-015369-72cjogxz 2365 21 rise rise VB cord-015369-72cjogxz 2365 22 . . . cord-015369-72cjogxz 2366 1 Pathogenisis Pathogenisis NNP cord-015369-72cjogxz 2366 2 seems seem VBZ cord-015369-72cjogxz 2366 3 to to TO cord-015369-72cjogxz 2366 4 be be VB cord-015369-72cjogxz 2366 5 multifactorial multifactorial JJ cord-015369-72cjogxz 2366 6 . . . cord-015369-72cjogxz 2367 1 Besides besides IN cord-015369-72cjogxz 2367 2 prophylaxis prophylaxis NN cord-015369-72cjogxz 2367 3 the the DT cord-015369-72cjogxz 2367 4 spectrum spectrum NN cord-015369-72cjogxz 2367 5 of of IN cord-015369-72cjogxz 2367 6 therapy therapy NN cord-015369-72cjogxz 2367 7 of of IN cord-015369-72cjogxz 2367 8 BRONJ BRONJ NNP cord-015369-72cjogxz 2367 9 reaches reach VBZ cord-015369-72cjogxz 2367 10 from from IN cord-015369-72cjogxz 2367 11 conservative conservative JJ cord-015369-72cjogxz 2367 12 meassures meassure NNS cord-015369-72cjogxz 2367 13 to to IN cord-015369-72cjogxz 2367 14 radical radical JJ cord-015369-72cjogxz 2367 15 - - HYPH cord-015369-72cjogxz 2367 16 surgical surgical JJ cord-015369-72cjogxz 2367 17 rehabilitation rehabilitation NN cord-015369-72cjogxz 2367 18 by by IN cord-015369-72cjogxz 2367 19 plastic plastic JJ cord-015369-72cjogxz 2367 20 reconstruction reconstruction NN cord-015369-72cjogxz 2367 21 with with IN cord-015369-72cjogxz 2367 22 local local JJ cord-015369-72cjogxz 2367 23 and and CC cord-015369-72cjogxz 2367 24 microvascular microvascular JJ cord-015369-72cjogxz 2367 25 flaps flap NNS cord-015369-72cjogxz 2367 26 . . . cord-015369-72cjogxz 2368 1 Furthermore furthermore RB cord-015369-72cjogxz 2368 2 experiences experience NNS cord-015369-72cjogxz 2368 3 of of IN cord-015369-72cjogxz 2368 4 our -PRON- PRP$ cord-015369-72cjogxz 2368 5 own own JJ cord-015369-72cjogxz 2368 6 patients patient NNS cord-015369-72cjogxz 2368 7 were be VBD cord-015369-72cjogxz 2368 8 compared compare VBN cord-015369-72cjogxz 2368 9 to to IN cord-015369-72cjogxz 2368 10 relevant relevant JJ cord-015369-72cjogxz 2368 11 literature literature NN cord-015369-72cjogxz 2368 12 . . . cord-015369-72cjogxz 2369 1 Summary summary NN cord-015369-72cjogxz 2369 2 . . . cord-015369-72cjogxz 2370 1 Concerning concern VBG cord-015369-72cjogxz 2370 2 our -PRON- PRP$ cord-015369-72cjogxz 2370 3 patients patient NNS cord-015369-72cjogxz 2370 4 ( ( -LRB- cord-015369-72cjogxz 2370 5 12 12 CD cord-015369-72cjogxz 2370 6 cases)the cases)the DT cord-015369-72cjogxz 2370 7 biggest big JJS cord-015369-72cjogxz 2370 8 percentage percentage NN cord-015369-72cjogxz 2370 9 of of IN cord-015369-72cjogxz 2370 10 relapse relapse NN cord-015369-72cjogxz 2370 11 - - HYPH cord-015369-72cjogxz 2370 12 free free JJ cord-015369-72cjogxz 2370 13 patients patient NNS cord-015369-72cjogxz 2370 14 could could MD cord-015369-72cjogxz 2370 15 be be VB cord-015369-72cjogxz 2370 16 reached reach VBN cord-015369-72cjogxz 2370 17 through through IN cord-015369-72cjogxz 2370 18 radical radical JJ cord-015369-72cjogxz 2370 19 surgical surgical JJ cord-015369-72cjogxz 2370 20 rehabilitation rehabilitation NN cord-015369-72cjogxz 2370 21 , , , cord-015369-72cjogxz 2370 22 where where WRB cord-015369-72cjogxz 2370 23 the the DT cord-015369-72cjogxz 2370 24 obtained obtain VBN cord-015369-72cjogxz 2370 25 defect defect NN cord-015369-72cjogxz 2370 26 is be VBZ cord-015369-72cjogxz 2370 27 to to TO cord-015369-72cjogxz 2370 28 be be VB cord-015369-72cjogxz 2370 29 reconstructed reconstruct VBN cord-015369-72cjogxz 2370 30 plastically plastically RB cord-015369-72cjogxz 2370 31 . . . cord-015369-72cjogxz 2371 1 The the DT cord-015369-72cjogxz 2371 2 results result NNS cord-015369-72cjogxz 2371 3 after after IN cord-015369-72cjogxz 2371 4 reconstruction reconstruction NN cord-015369-72cjogxz 2371 5 with with IN cord-015369-72cjogxz 2371 6 microvascular microvascular JJ cord-015369-72cjogxz 2371 7 iliac iliac NNP cord-015369-72cjogxz 2371 8 crest crest NN cord-015369-72cjogxz 2371 9 flap flap NN cord-015369-72cjogxz 2371 10 proved prove VBN cord-015369-72cjogxz 2371 11 to to TO cord-015369-72cjogxz 2371 12 be be VB cord-015369-72cjogxz 2371 13 most most RBS cord-015369-72cjogxz 2371 14 effective effective JJ cord-015369-72cjogxz 2371 15 . . . cord-015369-72cjogxz 2372 1 The the DT cord-015369-72cjogxz 2372 2 same same JJ cord-015369-72cjogxz 2372 3 results result NNS cord-015369-72cjogxz 2372 4 could could MD cord-015369-72cjogxz 2372 5 be be VB cord-015369-72cjogxz 2372 6 seen see VBN cord-015369-72cjogxz 2372 7 in in IN cord-015369-72cjogxz 2372 8 relevant relevant JJ cord-015369-72cjogxz 2372 9 literature literature NN cord-015369-72cjogxz 2372 10 . . . cord-015369-72cjogxz 2373 1 In in IN cord-015369-72cjogxz 2373 2 case case NN cord-015369-72cjogxz 2373 3 of of IN cord-015369-72cjogxz 2373 4 surgical surgical JJ cord-015369-72cjogxz 2373 5 decortication decortication NN cord-015369-72cjogxz 2373 6 plastic plastic NN cord-015369-72cjogxz 2373 7 reconstruction reconstruction NN cord-015369-72cjogxz 2373 8 proved prove VBN cord-015369-72cjogxz 2373 9 to to TO cord-015369-72cjogxz 2373 10 be be VB cord-015369-72cjogxz 2373 11 less less RBR cord-015369-72cjogxz 2373 12 difficult difficult JJ cord-015369-72cjogxz 2373 13 but but CC cord-015369-72cjogxz 2373 14 long long JJ cord-015369-72cjogxz 2373 15 - - HYPH cord-015369-72cjogxz 2373 16 term term NN cord-015369-72cjogxz 2373 17 results result NNS cord-015369-72cjogxz 2373 18 were be VBD cord-015369-72cjogxz 2373 19 not not RB cord-015369-72cjogxz 2373 20 satisfying satisfying JJ cord-015369-72cjogxz 2373 21 . . . cord-015369-72cjogxz 2374 1 Concluding conclude VBG cord-015369-72cjogxz 2374 2 there there EX cord-015369-72cjogxz 2374 3 is be VBZ cord-015369-72cjogxz 2374 4 to to TO cord-015369-72cjogxz 2374 5 say say VB cord-015369-72cjogxz 2374 6 that that IN cord-015369-72cjogxz 2374 7 the the DT cord-015369-72cjogxz 2374 8 present present JJ cord-015369-72cjogxz 2374 9 staging staging NN cord-015369-72cjogxz 2374 10 system system NN cord-015369-72cjogxz 2374 11 should should MD cord-015369-72cjogxz 2374 12 be be VB cord-015369-72cjogxz 2374 13 changed change VBN cord-015369-72cjogxz 2374 14 into into IN cord-015369-72cjogxz 2374 15 a a DT cord-015369-72cjogxz 2374 16 more more RBR cord-015369-72cjogxz 2374 17 comprehensive comprehensive JJ cord-015369-72cjogxz 2374 18 staging staging NN cord-015369-72cjogxz 2374 19 system system NN cord-015369-72cjogxz 2374 20 , , , cord-015369-72cjogxz 2374 21 which which WDT cord-015369-72cjogxz 2374 22 would would MD cord-015369-72cjogxz 2374 23 enable enable VB cord-015369-72cjogxz 2374 24 us -PRON- PRP cord-015369-72cjogxz 2374 25 to to TO cord-015369-72cjogxz 2374 26 make make VB cord-015369-72cjogxz 2374 27 even even RB cord-015369-72cjogxz 2374 28 more more RBR cord-015369-72cjogxz 2374 29 accurate accurate JJ cord-015369-72cjogxz 2374 30 judgements judgement NNS cord-015369-72cjogxz 2374 31 about about IN cord-015369-72cjogxz 2374 32 risk risk NN cord-015369-72cjogxz 2374 33 , , , cord-015369-72cjogxz 2374 34 prognosis prognosis NN cord-015369-72cjogxz 2374 35 , , , cord-015369-72cjogxz 2374 36 treatment treatment NN cord-015369-72cjogxz 2374 37 selection selection NN cord-015369-72cjogxz 2374 38 , , , cord-015369-72cjogxz 2374 39 and and CC cord-015369-72cjogxz 2374 40 outcome outcome NN cord-015369-72cjogxz 2374 41 for for IN cord-015369-72cjogxz 2374 42 patients patient NNS cord-015369-72cjogxz 2374 43 with with IN cord-015369-72cjogxz 2374 44 BRONJ BRONJ NNP cord-015369-72cjogxz 2374 45 . . . cord-015369-72cjogxz 2375 1 Therefore therefore RB cord-015369-72cjogxz 2375 2 more more RBR cord-015369-72cjogxz 2375 3 prospective prospective JJ cord-015369-72cjogxz 2375 4 clinical clinical JJ cord-015369-72cjogxz 2375 5 studies study NNS cord-015369-72cjogxz 2375 6 are be VBP cord-015369-72cjogxz 2375 7 required require VBN cord-015369-72cjogxz 2375 8 in in IN cord-015369-72cjogxz 2375 9 the the DT cord-015369-72cjogxz 2375 10 future future NN cord-015369-72cjogxz 2375 11 . . . cord-015369-72cjogxz 2376 1 Das Das NNP cord-015369-72cjogxz 2376 2 Calcitonin Calcitonin NNP cord-015369-72cjogxz 2376 3 - - HYPH cord-015369-72cjogxz 2376 4 Nasenspray Nasenspray NNP cord-015369-72cjogxz 2377 1 therapieresistente therapieresistente JJ cord-015369-72cjogxz 2378 1 reparative reparative JJ cord-015369-72cjogxz 2378 2 Riesenzellgranulom Riesenzellgranulom NNP cord-015369-72cjogxz 2378 3 -Ein -Ein NNP cord-015369-72cjogxz 2378 4 Fallbericht Fallbericht NNP cord-015369-72cjogxz 2379 1 Klinische Klinische NNP cord-015369-72cjogxz 2379 2 Abteilung Abteilung NNP cord-015369-72cjogxz 2379 3 für für IN cord-015369-72cjogxz 2379 4 Mund- Mund- NNP cord-015369-72cjogxz 2379 5 , , , cord-015369-72cjogxz 2379 6 Kiefer Kiefer NNP cord-015369-72cjogxz 2379 7 - - HYPH cord-015369-72cjogxz 2379 8 und und NNP cord-015369-72cjogxz 2379 9 Gesichtschirurgie Gesichtschirurgie NNP cord-015369-72cjogxz 2379 10 , , , cord-015369-72cjogxz 2379 11 Graz Graz NNP cord-015369-72cjogxz 2379 12 , , , cord-015369-72cjogxz 2379 13 Austria Austria NNP cord-015369-72cjogxz 2379 14 Grundlagen Grundlagen NNP cord-015369-72cjogxz 2379 15 . . . cord-015369-72cjogxz 2380 1 Das Das NNP cord-015369-72cjogxz 2380 2 reparative reparative NNP cord-015369-72cjogxz 2381 1 Riesenzellgranulom riesenzellgranulom NN cord-015369-72cjogxz 2381 2 wurde wurde NNP cord-015369-72cjogxz 2381 3 wegen wegen NNP cord-015369-72cjogxz 2381 4 seinem seinem NNP cord-015369-72cjogxz 2381 5 aggressiven aggressiven NNP cord-015369-72cjogxz 2381 6 Wachstum Wachstum NNP cord-015369-72cjogxz 2381 7 und und IN cord-015369-72cjogxz 2381 8 seiner seiner NNP cord-015369-72cjogxz 2381 9 Progredienz Progredienz NNP cord-015369-72cjogxz 2381 10 , , , cord-015369-72cjogxz 2381 11 zwar zwar FW cord-015369-72cjogxz 2381 12 als als NN cord-015369-72cjogxz 2381 13 nicht nicht NNP cord-015369-72cjogxz 2381 14 neo neo NNP cord-015369-72cjogxz 2381 15 - - HYPH cord-015369-72cjogxz 2381 16 plastische plastische NNP cord-015369-72cjogxz 2381 17 Veränderung Veränderung NNP cord-015369-72cjogxz 2381 18 beschrieben beschrieben NNP cord-015369-72cjogxz 2381 19 , , , cord-015369-72cjogxz 2382 1 jedoch jedoch NNP cord-015369-72cjogxz 2382 2 seine seine NNP cord-015369-72cjogxz 2382 3 morphologische morphologische NNP cord-015369-72cjogxz 2382 4 Ä Ä NNP cord-015369-72cjogxz 2382 5 hnlichkeit hnlichkeit NNP cord-015369-72cjogxz 2382 6 mit mit NNP cord-015369-72cjogxz 2382 7 einem einem NNP cord-015369-72cjogxz 2382 8 Riesenzelltumor Riesenzelltumor NNP cord-015369-72cjogxz 2382 9 rechtfertigte rechtfertigte NNP cord-015369-72cjogxz 2382 10 letztendlich letztendlich NNP cord-015369-72cjogxz 2382 11 eine eine NNP cord-015369-72cjogxz 2382 12 radikale radikale NN cord-015369-72cjogxz 2382 13 chirurgische chirurgische NNP cord-015369-72cjogxz 2382 14 Therapie Therapie NNP cord-015369-72cjogxz 2382 15 . . . cord-015369-72cjogxz 2383 1 Eine Eine NNP cord-015369-72cjogxz 2383 2 chirurgische chirurgische NN cord-015369-72cjogxz 2383 3 Entfernung Entfernung NNP cord-015369-72cjogxz 2383 4 zeigte zeigte NNP cord-015369-72cjogxz 2384 1 trotz trotz NNP cord-015369-72cjogxz 2384 2 einer einer NNP cord-015369-72cjogxz 2384 3 additiv additiv NNP cord-015369-72cjogxz 2385 1 angesetzten angesetzten NNP cord-015369-72cjogxz 2386 1 Calcitonin Calcitonin NNP cord-015369-72cjogxz 2386 2 - - HYPH cord-015369-72cjogxz 2386 3 Nasenspraytherapie Nasenspraytherapie NNP cord-015369-72cjogxz 2386 4 ein ein NNP cord-015369-72cjogxz 2386 5 Rezidiv Rezidiv NNP cord-015369-72cjogxz 2386 6 . . . cord-015369-72cjogxz 2387 1 Beim Beim NNP cord-015369-72cjogxz 2387 2 reparativen reparativen NNP cord-015369-72cjogxz 2387 3 Riesenzellgranulom Riesenzellgranulom NNP cord-015369-72cjogxz 2387 4 handelte handelte NNP cord-015369-72cjogxz 2388 1 es es NNP cord-015369-72cjogxz 2388 2 sich sich NNP cord-015369-72cjogxz 2388 3 um um UH cord-015369-72cjogxz 2388 4 eine eine NNP cord-015369-72cjogxz 2388 5 seltene seltene NNP cord-015369-72cjogxz 2388 6 intraossäre intraossäre NNP cord-015369-72cjogxz 2388 7 Läsion Läsion NNP cord-015369-72cjogxz 2388 8 , , , cord-015369-72cjogxz 2388 9 welche welche NNP cord-015369-72cjogxz 2388 10 vor vor NNP cord-015369-72cjogxz 2388 11 dem dem NNP cord-015369-72cjogxz 2388 12 30 30 CD cord-015369-72cjogxz 2388 13 . . . cord-015369-72cjogxz 2389 1 Lebensjahr Lebensjahr NNP cord-015369-72cjogxz 2389 2 auftrat auftrat NNP cord-015369-72cjogxz 2389 3 und und IN cord-015369-72cjogxz 2389 4 eine eine NNP cord-015369-72cjogxz 2390 1 rasche rasche NNP cord-015369-72cjogxz 2390 2 indolente indolente NNP cord-015369-72cjogxz 2390 3 Auftreibung Auftreibung NNP cord-015369-72cjogxz 2390 4 des des FW cord-015369-72cjogxz 2390 5 Kieferknochens Kieferknochens NNP cord-015369-72cjogxz 2390 6 zeigte zeigte NNP cord-015369-72cjogxz 2390 7 . . . cord-015369-72cjogxz 2391 1 Methodik Methodik NNP cord-015369-72cjogxz 2391 2 . . . cord-015369-72cjogxz 2392 1 Bei Bei NNP cord-015369-72cjogxz 2392 2 einer einer NNP cord-015369-72cjogxz 2393 1 17 17 CD cord-015369-72cjogxz 2393 2 jährigen jährigen NNP cord-015369-72cjogxz 2393 3 Patientin Patientin NNP cord-015369-72cjogxz 2393 4 war war NN cord-015369-72cjogxz 2394 1 i i PRP cord-015369-72cjogxz 2395 1 m m NNP cord-015369-72cjogxz 2395 2 November November NNP cord-015369-72cjogxz 2395 3 2007 2007 CD cord-015369-72cjogxz 2395 4 ein ein NNP cord-015369-72cjogxz 2395 5 langsam langsam NNP cord-015369-72cjogxz 2395 6 wachsender wachsender NNP cord-015369-72cjogxz 2395 7 schmerzloser schmerzloser NNP cord-015369-72cjogxz 2395 8 Tumor Tumor NNP cord-015369-72cjogxz 2396 1 i -PRON- PRP cord-015369-72cjogxz 2396 2 m be VBP cord-015369-72cjogxz 2396 3 Kieferwinkel Kieferwinkel NNP cord-015369-72cjogxz 2396 4 links link VBZ cord-015369-72cjogxz 2396 5 diagnostiziert diagnostiziert NNP cord-015369-72cjogxz 2396 6 worden worden NNP cord-015369-72cjogxz 2396 7 . . . cord-015369-72cjogxz 2397 1 I -PRON- PRP cord-015369-72cjogxz 2397 2 m be VBP cord-015369-72cjogxz 2397 3 Februar Februar NNP cord-015369-72cjogxz 2397 4 2008 2008 CD cord-015369-72cjogxz 2397 5 wurde wurde NNP cord-015369-72cjogxz 2397 6 eine eine NNP cord-015369-72cjogxz 2397 7 Exstirpation Exstirpation NNP cord-015369-72cjogxz 2397 8 des des NNP cord-015369-72cjogxz 2397 9 Tumors Tumors NNP cord-015369-72cjogxz 2397 10 durchgeführt durchgeführt NN cord-015369-72cjogxz 2398 1 und und UH cord-015369-72cjogxz 2398 2 die die VB cord-015369-72cjogxz 2398 3 Zähne Zähne NNP cord-015369-72cjogxz 2398 4 36 36 CD cord-015369-72cjogxz 2398 5 , , , cord-015369-72cjogxz 2398 6 37 37 CD cord-015369-72cjogxz 2398 7 wurden wurden NNS cord-015369-72cjogxz 2398 8 extrahiert extrahiert JJ cord-015369-72cjogxz 2398 9 . . . cord-015369-72cjogxz 2399 1 Die die VB cord-015369-72cjogxz 2399 2 Patientin Patientin NNP cord-015369-72cjogxz 2399 3 erhielt erhielt NNP cord-015369-72cjogxz 2399 4 postoperativ postoperativ NNP cord-015369-72cjogxz 2399 5 additiv additiv NNP cord-015369-72cjogxz 2399 6 einen einen NNP cord-015369-72cjogxz 2399 7 Calcitonin Calcitonin NNP cord-015369-72cjogxz 2399 8 - - HYPH cord-015369-72cjogxz 2399 9 Nasalspray Nasalspray NNP cord-015369-72cjogxz 2399 10 mit mit VBD cord-015369-72cjogxz 2399 11 100 100 CD cord-015369-72cjogxz 2399 12 I.E I.E NNP cord-015369-72cjogxz 2399 13 täglich täglich NNS cord-015369-72cjogxz 2399 14 . . . cord-015369-72cjogxz 2400 1 Bei Bei NNP cord-015369-72cjogxz 2400 2 regelmäßigen regelmäßigen NNP cord-015369-72cjogxz 2400 3 Kontrollen Kontrollen NNP cord-015369-72cjogxz 2400 4 zeigte zeigte NNP cord-015369-72cjogxz 2400 5 sich sich NNP cord-015369-72cjogxz 2400 6 trotz trotz NNP cord-015369-72cjogxz 2400 7 regelmäßiger regelmäßiger NNP cord-015369-72cjogxz 2400 8 Einnahme Einnahme NNP cord-015369-72cjogxz 2400 9 des des FW cord-015369-72cjogxz 2400 10 Medikamentes Medikamentes NNP cord-015369-72cjogxz 2400 11 nach nach NNP cord-015369-72cjogxz 2400 12 5 5 CD cord-015369-72cjogxz 2400 13 Monaten Monaten NNP cord-015369-72cjogxz 2400 14 ein ein NNP cord-015369-72cjogxz 2400 15 doppelt doppelt NNP cord-015369-72cjogxz 2401 1 so so RB cord-015369-72cjogxz 2401 2 großes großes NNP cord-015369-72cjogxz 2401 3 Rezidiv Rezidiv NNP cord-015369-72cjogxz 2402 1 i -PRON- PRP cord-015369-72cjogxz 2402 2 m be VBP cord-015369-72cjogxz 2402 3 Unterkiefer Unterkiefer NNP cord-015369-72cjogxz 2402 4 links link NNS cord-015369-72cjogxz 2402 5 . . . cord-015369-72cjogxz 2403 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2403 2 . . . cord-015369-72cjogxz 2404 1 Das Das NNP cord-015369-72cjogxz 2404 2 Rezidiv Rezidiv NNP cord-015369-72cjogxz 2404 3 wurde wurde NNP cord-015369-72cjogxz 2404 4 teilreseziert teilreseziert NNP cord-015369-72cjogxz 2405 1 und und NNP cord-015369-72cjogxz 2405 2 operativ operativ NNP cord-015369-72cjogxz 2405 3 mit mit NNP cord-015369-72cjogxz 2405 4 einem einem NNP cord-015369-72cjogxz 2405 5 mikrochirurgisch mikrochirurgisch NNP cord-015369-72cjogxz 2405 6 anastomisierten anastomisierten NNP cord-015369-72cjogxz 2406 1 Beckenkammknochen Beckenkammknochen NNP cord-015369-72cjogxz 2407 1 i -PRON- PRP cord-015369-72cjogxz 2407 2 m be VBP cord-015369-72cjogxz 2407 3 Unterkiefer Unterkiefer NNP cord-015369-72cjogxz 2407 4 links link VBZ cord-015369-72cjogxz 2407 5 rekonstruiert rekonstruiert NNP cord-015369-72cjogxz 2407 6 . . . cord-015369-72cjogxz 2408 1 Die die VB cord-015369-72cjogxz 2408 2 Calcitonin Calcitonin NNP cord-015369-72cjogxz 2408 3 - - HYPH cord-015369-72cjogxz 2408 4 Nasenspraytherapie Nasenspraytherapie NNP cord-015369-72cjogxz 2408 5 wurde wurde NN cord-015369-72cjogxz 2408 6 postoperativ postoperativ NNP cord-015369-72cjogxz 2408 7 sofort sofort NNP cord-015369-72cjogxz 2408 8 abgesetzt abgesetzt VBD cord-015369-72cjogxz 2408 9 . . . cord-015369-72cjogxz 2409 1 Diskussion Diskussion NNP cord-015369-72cjogxz 2409 2 . . . cord-015369-72cjogxz 2410 1 Die die VB cord-015369-72cjogxz 2410 2 radikale radikale NN cord-015369-72cjogxz 2411 1 chirurgische chirurgische NNP cord-015369-72cjogxz 2411 2 Entfernung Entfernung NNP cord-015369-72cjogxz 2411 3 der der NNP cord-015369-72cjogxz 2412 1 Läsion Läsion NNP cord-015369-72cjogxz 2412 2 unter unter NNP cord-015369-72cjogxz 2412 3 Erhaltung Erhaltung NNP cord-015369-72cjogxz 2412 4 der der NNP cord-015369-72cjogxz 2412 5 Funktion Funktion NNP cord-015369-72cjogxz 2412 6 war war NN cord-015369-72cjogxz 2412 7 eine eine NN cord-015369-72cjogxz 2412 8 effiziente effiziente FW cord-015369-72cjogxz 2412 9 Therapie Therapie NNP cord-015369-72cjogxz 2412 10 , , , cord-015369-72cjogxz 2413 1 zeigte zeigte NNP cord-015369-72cjogxz 2413 2 jedoch jedoch NNP cord-015369-72cjogxz 2413 3 bei bei NNP cord-015369-72cjogxz 2413 4 der der NNP cord-015369-72cjogxz 2413 5 Entstehung Entstehung NNP cord-015369-72cjogxz 2413 6 eines eines NNP cord-015369-72cjogxz 2413 7 Rezidivs Rezidivs NNP cord-015369-72cjogxz 2413 8 in in IN cord-015369-72cjogxz 2413 9 diesem diesem JJ cord-015369-72cjogxz 2413 10 Fall Fall NNP cord-015369-72cjogxz 2413 11 keinen keinen NNP cord-015369-72cjogxz 2413 12 weiteren weiteren NNP cord-015369-72cjogxz 2413 13 Anhalt Anhalt NNP cord-015369-72cjogxz 2414 1 für für NNP cord-015369-72cjogxz 2414 2 die die VBP cord-015369-72cjogxz 2414 3 Fortsetzung Fortsetzung NNP cord-015369-72cjogxz 2414 4 des des NNP cord-015369-72cjogxz 2414 5 Calcitonin Calcitonin NNP cord-015369-72cjogxz 2414 6 - - HYPH cord-015369-72cjogxz 2414 7 Nasensprays Nasensprays NNP cord-015369-72cjogxz 2414 8 additiv additiv NN cord-015369-72cjogxz 2414 9 . . . cord-015369-72cjogxz 2415 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 2415 2 . . . cord-015369-72cjogxz 2416 1 Es Es NNP cord-015369-72cjogxz 2416 2 wurde wurde NNP cord-015369-72cjogxz 2416 3 anhand anhand NNP cord-015369-72cjogxz 2417 1 eines eines NNP cord-015369-72cjogxz 2417 2 Fallberichtes Fallberichtes NNPS cord-015369-72cjogxz 2417 3 bei bei NNP cord-015369-72cjogxz 2417 4 einer einer NNP cord-015369-72cjogxz 2418 1 17-jährigen 17-jährigen CD cord-015369-72cjogxz 2419 1 Patientin Patientin NNP cord-015369-72cjogxz 2419 2 die die VBP cord-015369-72cjogxz 2419 3 Therapie Therapie NNP cord-015369-72cjogxz 2419 4 einer einer NNP cord-015369-72cjogxz 2420 1 Exstirpation Exstirpation NNP cord-015369-72cjogxz 2420 2 des des NNP cord-015369-72cjogxz 2420 3 Tumors Tumors NNP cord-015369-72cjogxz 2420 4 mit mit NNP cord-015369-72cjogxz 2420 5 additiver additiver NN cord-015369-72cjogxz 2420 6 Therapie Therapie NNP cord-015369-72cjogxz 2420 7 eines eines NNP cord-015369-72cjogxz 2420 8 Calcitonin Calcitonin NNP cord-015369-72cjogxz 2420 9 - - HYPH cord-015369-72cjogxz 2420 10 Nasensprays Nasensprays NNP cord-015369-72cjogxz 2420 11 , , , cord-015369-72cjogxz 2420 12 dem dem NNP cord-015369-72cjogxz 2420 13 einer einer NNP cord-015369-72cjogxz 2420 14 radikalen radikalen NNP cord-015369-72cjogxz 2420 15 chirurgischen chirurgischen NNP cord-015369-72cjogxz 2420 16 Behandlung Behandlung NNP cord-015369-72cjogxz 2420 17 , , , cord-015369-72cjogxz 2420 18 bei bei NNP cord-015369-72cjogxz 2420 19 einem einem NNP cord-015369-72cjogxz 2420 20 reparativen reparativen NNP cord-015369-72cjogxz 2420 21 Riesenzellgranulom Riesenzellgranulom NNP cord-015369-72cjogxz 2420 22 , , , cord-015369-72cjogxz 2421 1 gegenübergestellt gegenübergestellt NNP cord-015369-72cjogxz 2421 2 und und NNP cord-015369-72cjogxz 2421 3 diskutiert diskutiert NNP cord-015369-72cjogxz 2421 4 . . . cord-015369-72cjogxz 2422 1 Ein Ein NNP cord-015369-72cjogxz 2422 2 Rezidiv Rezidiv NNP cord-015369-72cjogxz 2422 3 bei bei NNP cord-015369-72cjogxz 2422 4 dieser dieser NNP cord-015369-72cjogxz 2422 5 Patientin Patientin NNP cord-015369-72cjogxz 2422 6 erforderte erforderte VBP cord-015369-72cjogxz 2422 7 eine eine NNP cord-015369-72cjogxz 2422 8 radikale radikale NN cord-015369-72cjogxz 2423 1 chirurgische chirurgische NNP cord-015369-72cjogxz 2423 2 Teilresektion Teilresektion NNP cord-015369-72cjogxz 2423 3 und und IN cord-015369-72cjogxz 2423 4 Rekonstruktion Rekonstruktion NNP cord-015369-72cjogxz 2423 5 des des NNP cord-015369-72cjogxz 2423 6 Unterkiefers Unterkiefers NNP cord-015369-72cjogxz 2423 7 , , , cord-015369-72cjogxz 2423 8 wobei wobei NNP cord-015369-72cjogxz 2423 9 eine eine NNP cord-015369-72cjogxz 2423 10 additive additive NN cord-015369-72cjogxz 2423 11 Calcitonin Calcitonin NNP cord-015369-72cjogxz 2423 12 - - HYPH cord-015369-72cjogxz 2423 13 Nasenspraytherapie Nasenspraytherapie NNP cord-015369-72cjogxz 2423 14 keine keine NN cord-015369-72cjogxz 2423 15 Vermeidung Vermeidung NNP cord-015369-72cjogxz 2423 16 eines eines NNP cord-015369-72cjogxz 2423 17 Rezidivs Rezidivs NNP cord-015369-72cjogxz 2423 18 bewirkte bewirkte NNP cord-015369-72cjogxz 2423 19 . . . cord-015369-72cjogxz 2424 1 Die die VB cord-015369-72cjogxz 2424 2 Funktion Funktion NNP cord-015369-72cjogxz 2424 3 des des FW cord-015369-72cjogxz 2424 4 Kieferknochens Kieferknochens NNP cord-015369-72cjogxz 2424 5 kann kann NNP cord-015369-72cjogxz 2424 6 durch durch NNP cord-015369-72cjogxz 2424 7 neoadjuvante neoadjuvante NNP cord-015369-72cjogxz 2424 8 , , , cord-015369-72cjogxz 2424 9 adjuvante adjuvante NNP cord-015369-72cjogxz 2424 10 und und IN cord-015369-72cjogxz 2424 11 auch auch NNP cord-015369-72cjogxz 2424 12 alleinige alleinige NNP cord-015369-72cjogxz 2425 1 Radiotherapieoptionen Radiotherapieoptionen NNP cord-015369-72cjogxz 2425 2 ausgelöst ausgelöst NNP cord-015369-72cjogxz 2425 3 verloren verloren NNP cord-015369-72cjogxz 2425 4 gehen gehen NNP cord-015369-72cjogxz 2425 5 , , , cord-015369-72cjogxz 2425 6 pathologische pathologische NN cord-015369-72cjogxz 2425 7 Frakturen Frakturen NNP cord-015369-72cjogxz 2425 8 und und IN cord-015369-72cjogxz 2425 9 Osteoradionekrosen Osteoradionekrosen NNP cord-015369-72cjogxz 2425 10 sind sind NNP cord-015369-72cjogxz 2425 11 als als NN cord-015369-72cjogxz 2426 1 Folgen Folgen NNP cord-015369-72cjogxz 2426 2 dieser dieser NNP cord-015369-72cjogxz 2426 3 Behandlung Behandlung NNP cord-015369-72cjogxz 2426 4 von von NNP cord-015369-72cjogxz 2426 5 Patienten Patienten NNP cord-015369-72cjogxz 2426 6 mit mit NNP cord-015369-72cjogxz 2426 7 Kopf Kopf NNP cord-015369-72cjogxz 2426 8 - - HYPH cord-015369-72cjogxz 2426 9 Halstumoren Halstumoren NNP cord-015369-72cjogxz 2426 10 bekannt bekannt NNP cord-015369-72cjogxz 2426 11 . . . cord-015369-72cjogxz 2427 1 Bestrahlungsdosierungen Bestrahlungsdosierungen NNP cord-015369-72cjogxz 2427 2 beruhen beruhen NNP cord-015369-72cjogxz 2428 1 dabei dabei NNP cord-015369-72cjogxz 2428 2 vor vor NNP cord-015369-72cjogxz 2428 3 allem allem NNP cord-015369-72cjogxz 2428 4 auf auf NNP cord-015369-72cjogxz 2428 5 empirischen empirischen NNP cord-015369-72cjogxz 2428 6 Konzepten Konzepten NNP cord-015369-72cjogxz 2428 7 -Erfahrungen -Erfahrungen NNP cord-015369-72cjogxz 2428 8 bei bei NNP cord-015369-72cjogxz 2428 9 der der NNP cord-015369-72cjogxz 2428 10 Therapie Therapie NNP cord-015369-72cjogxz 2428 11 früherer früherer NN cord-015369-72cjogxz 2428 12 Patienten Patienten NNP cord-015369-72cjogxz 2428 13 . . . cord-015369-72cjogxz 2429 1 In in IN cord-015369-72cjogxz 2429 2 der der NN cord-015369-72cjogxz 2429 3 Literatur Literatur NNP cord-015369-72cjogxz 2429 4 ist ist NN cord-015369-72cjogxz 2429 5 wenig wenig NNP cord-015369-72cjogxz 2429 6 darüber darüber NNP cord-015369-72cjogxz 2429 7 bekannt bekannt NNP cord-015369-72cjogxz 2429 8 inwieweit inwieweit NNP cord-015369-72cjogxz 2429 9 bestrahlter bestrahlter NNP cord-015369-72cjogxz 2430 1 Knochen Knochen NNP cord-015369-72cjogxz 2430 2 auf auf NNP cord-015369-72cjogxz 2430 3 stimulierende stimulierende RB cord-015369-72cjogxz 2430 4 Reize Reize NNP cord-015369-72cjogxz 2430 5 noch noch NNP cord-015369-72cjogxz 2430 6 reagieren reagieren NNP cord-015369-72cjogxz 2430 7 kann kann NNP cord-015369-72cjogxz 2430 8 , , , cord-015369-72cjogxz 2430 9 ob ob NNP cord-015369-72cjogxz 2430 10 die die VBP cord-015369-72cjogxz 2431 1 für für NNP cord-015369-72cjogxz 2431 2 die die VBP cord-015369-72cjogxz 2431 3 Knochenhomöostase Knochenhomöostase NNP cord-015369-72cjogxz 2432 1 essentiellen essentiellen NNP cord-015369-72cjogxz 2432 2 mesenchymalen mesenchymalen VBN cord-015369-72cjogxz 2432 3 Stammzellen Stammzellen NNP cord-015369-72cjogxz 2432 4 ( ( -LRB- cord-015369-72cjogxz 2432 5 MSCs MSCs NNP cord-015369-72cjogxz 2432 6 ) ) -RRB- cord-015369-72cjogxz 2432 7 die die VB cord-015369-72cjogxz 2432 8 Bestrahlung Bestrahlung NNP cord-015369-72cjogxz 2432 9 tolerieren tolerieren NNP cord-015369-72cjogxz 2433 1 und und IN cord-015369-72cjogxz 2433 2 ihr ihr NNP cord-015369-72cjogxz 2433 3 Differenzierungspotential Differenzierungspotential NNP cord-015369-72cjogxz 2433 4 darunter darunter NNP cord-015369-72cjogxz 2433 5 leidet leidet NNP cord-015369-72cjogxz 2433 6 . . . cord-015369-72cjogxz 2434 1 I -PRON- PRP cord-015369-72cjogxz 2435 1 m m NNP cord-015369-72cjogxz 2435 2 Rahmen Rahmen NNP cord-015369-72cjogxz 2436 1 der der NNP cord-015369-72cjogxz 2436 2 Bestrahlung Bestrahlung NNP cord-015369-72cjogxz 2437 1 werden werden NNP cord-015369-72cjogxz 2437 2 neben neben NNP cord-015369-72cjogxz 2437 3 dem dem NNP cord-015369-72cjogxz 2437 4 eigentlichen eigentlichen NNP cord-015369-72cjogxz 2437 5 Zielvolumen Zielvolumen NNP cord-015369-72cjogxz 2437 6 , , , cord-015369-72cjogxz 2438 1 , , , cord-015369-72cjogxz 2438 2 entartete entartete NNP cord-015369-72cjogxz 2438 3 Krebszellen Krebszellen NNP cord-015369-72cjogxz 2438 4 ' ' POS cord-015369-72cjogxz 2438 5 ' ' `` cord-015369-72cjogxz 2438 6 auch auch JJ cord-015369-72cjogxz 2438 7 alle alle NNP cord-015369-72cjogxz 2438 8 gesunden gesunden JJ cord-015369-72cjogxz 2438 9 Zellen Zellen NNP cord-015369-72cjogxz 2438 10 samt samt NNP cord-015369-72cjogxz 2439 1 den den NNP cord-015369-72cjogxz 2439 2 i -PRON- PRP cord-015369-72cjogxz 2439 3 m be VBP cord-015369-72cjogxz 2439 4 Knochen Knochen NNP cord-015369-72cjogxz 2439 5 eingebetteten eingebetteten NNP cord-015369-72cjogxz 2439 6 MSCs MSCs NNP cord-015369-72cjogxz 2439 7 getroffen getroffen NNP cord-015369-72cjogxz 2439 8 . . . cord-015369-72cjogxz 2440 1 In in IN cord-015369-72cjogxz 2440 2 dieser dieser NNP cord-015369-72cjogxz 2440 3 Studie Studie NNP cord-015369-72cjogxz 2440 4 wurden wurden NNP cord-015369-72cjogxz 2440 5 deshalb deshalb NNP cord-015369-72cjogxz 2440 6 einerseits einerseit VBZ cord-015369-72cjogxz 2440 7 humane humane JJ cord-015369-72cjogxz 2440 8 MSCs MSCs NNP cord-015369-72cjogxz 2440 9 und und NNP cord-015369-72cjogxz 2440 10 andererseits andererseit NNS cord-015369-72cjogxz 2441 1 porcine porcine JJ cord-015369-72cjogxz 2441 2 MSCs MSCs . cord-015369-72cjogxz 2442 1 vom vom NNP cord-015369-72cjogxz 2442 2 Unterkiefer Unterkiefer NNP cord-015369-72cjogxz 2442 3 des des FW cord-015369-72cjogxz 2442 4 sus sus FW cord-015369-72cjogxz 2442 5 scrofa scrofa NN cord-015369-72cjogxz 2443 1 domestica domestica NNP cord-015369-72cjogxz 2443 2 auf auf NNP cord-015369-72cjogxz 2443 3 ihre ihre NNP cord-015369-72cjogxz 2443 4 Bestrahlungssensitivität Bestrahlungssensitivität NNP cord-015369-72cjogxz 2444 1 in in IN cord-015369-72cjogxz 2444 2 vitro vitro FW cord-015369-72cjogxz 2445 1 und und NNP cord-015369-72cjogxz 2446 1 i -PRON- PRP cord-015369-72cjogxz 2446 2 m be VBP cord-015369-72cjogxz 2446 3 Gewebeverband Gewebeverband NNP cord-015369-72cjogxz 2446 4 in in IN cord-015369-72cjogxz 2446 5 drei drei NNP cord-015369-72cjogxz 2446 6 Stufen Stufen NNP cord-015369-72cjogxz 2446 7 analysiert analysiert NN cord-015369-72cjogxz 2446 8 . . . cord-015369-72cjogxz 2447 1 Zunächst Zunächst NNP cord-015369-72cjogxz 2447 2 wurden wurden VBD cord-015369-72cjogxz 2448 1 humane humane JJ cord-015369-72cjogxz 2448 2 und und IN cord-015369-72cjogxz 2448 3 porcine porcine JJ cord-015369-72cjogxz 2448 4 MSCs MSCs NNP cord-015369-72cjogxz 2448 5 isoliert isoliert NNP cord-015369-72cjogxz 2448 6 und und NNP cord-015369-72cjogxz 2448 7 in in IN cord-015369-72cjogxz 2448 8 vitro vitro FW cord-015369-72cjogxz 2448 9 bestrahlt bestrahlt NNP cord-015369-72cjogxz 2448 10 . . . cord-015369-72cjogxz 2449 1 Einerseits Einerseits NNP cord-015369-72cjogxz 2449 2 zeigte zeigte NNP cord-015369-72cjogxz 2449 3 sich sich NNP cord-015369-72cjogxz 2449 4 , , , cord-015369-72cjogxz 2449 5 wie wie NNP cord-015369-72cjogxz 2449 6 erwartet erwartet NNP cord-015369-72cjogxz 2449 7 , , , cord-015369-72cjogxz 2449 8 eine eine NNP cord-015369-72cjogxz 2449 9 kohärente kohärente NNP cord-015369-72cjogxz 2449 10 Abnahme Abnahme NNP cord-015369-72cjogxz 2449 11 der der NNP cord-015369-72cjogxz 2449 12 Proliferationskapazität Proliferationskapazität NNP cord-015369-72cjogxz 2449 13 mit mit NN cord-015369-72cjogxz 2449 14 zunehmenden zunehmenden NNP cord-015369-72cjogxz 2449 15 Dosen Dosen NNP cord-015369-72cjogxz 2449 16 , , , cord-015369-72cjogxz 2450 1 aber aber NNP cord-015369-72cjogxz 2450 2 andererseits andererseits NNP cord-015369-72cjogxz 2450 3 blieb blieb NNP cord-015369-72cjogxz 2450 4 die die NNP cord-015369-72cjogxz 2450 5 osteo osteo NNP cord-015369-72cjogxz 2450 6 - - HYPH cord-015369-72cjogxz 2450 7 und und NNP cord-015369-72cjogxz 2450 8 adipogene adipogene NNP cord-015369-72cjogxz 2451 1 Differenzierungsfähigkeit Differenzierungsfähigkeit NNP cord-015369-72cjogxz 2451 2 erhalten erhalten NNP cord-015369-72cjogxz 2451 3 , , , cord-015369-72cjogxz 2451 4 annähernd annähernd NNP cord-015369-72cjogxz 2451 5 ähnlich ähnlich NNP cord-015369-72cjogxz 2451 6 den den NNP cord-015369-72cjogxz 2451 7 unbestrahlten unbestrahlten JJ cord-015369-72cjogxz 2451 8 Kontrollproben Kontrollproben NNP cord-015369-72cjogxz 2451 9 . . . cord-015369-72cjogxz 2452 1 Anschliessend Anschliessend NNP cord-015369-72cjogxz 2452 2 wurden wurden NNS cord-015369-72cjogxz 2452 3 die die VBP cord-015369-72cjogxz 2452 4 Unterkiefer Unterkiefer NNP cord-015369-72cjogxz 2452 5 von von NNP cord-015369-72cjogxz 2452 6 sus sus NNP cord-015369-72cjogxz 2452 7 scrofa scrofa NNP cord-015369-72cjogxz 2452 8 domestica domestica NN cord-015369-72cjogxz 2453 1 mit mit NNP cord-015369-72cjogxz 2453 2 einer einer NNP cord-015369-72cjogxz 2453 3 Dosis Dosis NNP cord-015369-72cjogxz 2453 4 von von NNP cord-015369-72cjogxz 2453 5 2 2 CD cord-015369-72cjogxz 2453 6 Â â NN cord-015369-72cjogxz 2453 7 9 9 CD cord-015369-72cjogxz 2453 8 Gy gy NN cord-015369-72cjogxz 2454 1 i -PRON- PRP cord-015369-72cjogxz 2454 2 m be VBP cord-015369-72cjogxz 2454 3 Wochenabstand Wochenabstand NNP cord-015369-72cjogxz 2454 4 bestrahlt bestrahlt NNP cord-015369-72cjogxz 2454 5 . . . cord-015369-72cjogxz 2455 1 Zu Zu NNP cord-015369-72cjogxz 2455 2 verschiedenen verschiedenen NNP cord-015369-72cjogxz 2455 3 Zeitpunkten Zeitpunkten NNP cord-015369-72cjogxz 2455 4 ( ( -LRB- cord-015369-72cjogxz 2455 5 nach nach NNP cord-015369-72cjogxz 2455 6 5 5 CD cord-015369-72cjogxz 2455 7 , , , cord-015369-72cjogxz 2455 8 6 6 CD cord-015369-72cjogxz 2455 9 , , , cord-015369-72cjogxz 2455 10 8 8 CD cord-015369-72cjogxz 2455 11 und und IN cord-015369-72cjogxz 2455 12 12 12 CD cord-015369-72cjogxz 2455 13 Wochen Wochen NNP cord-015369-72cjogxz 2455 14 ) ) -RRB- cord-015369-72cjogxz 2455 15 wurden wurden NNS cord-015369-72cjogxz 2455 16 die die VBP cord-015369-72cjogxz 2455 17 MSCs msc NNS cord-015369-72cjogxz 2455 18 aus aus NNP cord-015369-72cjogxz 2455 19 Knochenbiopsien Knochenbiopsien NNP cord-015369-72cjogxz 2455 20 gewonnen gewonnen NNP cord-015369-72cjogxz 2455 21 . . . cord-015369-72cjogxz 2456 1 Interessanterweise Interessanterweise NNP cord-015369-72cjogxz 2456 2 bestanden bestanden NNP cord-015369-72cjogxz 2457 1 keine keine NNP cord-015369-72cjogxz 2457 2 signifikanten signifikanten NNP cord-015369-72cjogxz 2458 1 Unterschiede Unterschiede NNP cord-015369-72cjogxz 2458 2 zwischen zwischen NNP cord-015369-72cjogxz 2458 3 bestrahlten bestrahlten NNP cord-015369-72cjogxz 2459 1 und und IN cord-015369-72cjogxz 2459 2 unbestrahlten unbestrahlten NNP cord-015369-72cjogxz 2459 3 MSCs MSCs NNP cord-015369-72cjogxz 2459 4 hinsichtlich hinsichtlich NNP cord-015369-72cjogxz 2459 5 Proliferations Proliferations NNP cord-015369-72cjogxz 2459 6 - - HYPH cord-015369-72cjogxz 2459 7 als als NNP cord-015369-72cjogxz 2459 8 auch auch NNP cord-015369-72cjogxz 2459 9 osteogenem osteogenem NNP cord-015369-72cjogxz 2459 10 Differenzierungsverhalten Differenzierungsverhalten NNP cord-015369-72cjogxz 2459 11 . . . cord-015369-72cjogxz 2460 1 Deshalb Deshalb NNP cord-015369-72cjogxz 2460 2 wurden wurden VBD cord-015369-72cjogxz 2460 3 in in IN cord-015369-72cjogxz 2460 4 einer einer NNP cord-015369-72cjogxz 2460 5 weiteren weiteren NNP cord-015369-72cjogxz 2461 1 Analyse Analyse NNP cord-015369-72cjogxz 2461 2 Unterkiefer Unterkiefer NNP cord-015369-72cjogxz 2461 3 mit mit NNP cord-015369-72cjogxz 2461 4 9 9 CD cord-015369-72cjogxz 2461 5 und und XX cord-015369-72cjogxz 2462 1 18 18 CD cord-015369-72cjogxz 2462 2 Gy Gy NNP cord-015369-72cjogxz 2462 3 bestrahlt bestrahlt NNP cord-015369-72cjogxz 2463 1 und und NNP cord-015369-72cjogxz 2463 2 am be VBP cord-015369-72cjogxz 2463 3 gleichen gleichen NNP cord-015369-72cjogxz 2463 4 Tag Tag NNP cord-015369-72cjogxz 2463 5 MSCs MSCs NNP cord-015369-72cjogxz 2464 1 aus aus NNP cord-015369-72cjogxz 2464 2 dem dem NNP cord-015369-72cjogxz 2464 3 bestrahlten bestrahlten NNP cord-015369-72cjogxz 2465 1 Knochen Knochen NNP cord-015369-72cjogxz 2465 2 entnommen entnommen NNP cord-015369-72cjogxz 2465 3 . . . cord-015369-72cjogxz 2466 1 Es Es NNP cord-015369-72cjogxz 2466 2 zeigte zeigte NNP cord-015369-72cjogxz 2466 3 sich sich NNP cord-015369-72cjogxz 2466 4 kein kein NNP cord-015369-72cjogxz 2466 5 signifikanter signifikanter NNP cord-015369-72cjogxz 2466 6 Unterschied Unterschied NNP cord-015369-72cjogxz 2466 7 zwischen zwischen NNP cord-015369-72cjogxz 2466 8 0 0 CD cord-015369-72cjogxz 2466 9 Gy Gy NNP cord-015369-72cjogxz 2466 10 - - HYPH cord-015369-72cjogxz 2466 11 Proben Proben NNP cord-015369-72cjogxz 2466 12 ( ( -LRB- cord-015369-72cjogxz 2466 13 unbestrahlt unbestrahlt NNP cord-015369-72cjogxz 2466 14 ) ) -RRB- cord-015369-72cjogxz 2466 15 und und RB cord-015369-72cjogxz 2467 1 9 9 CD cord-015369-72cjogxz 2467 2 Gy Gy NNP cord-015369-72cjogxz 2467 3 - - HYPH cord-015369-72cjogxz 2467 4 Proben Proben NNP cord-015369-72cjogxz 2467 5 bezüglich bezüglich NNP cord-015369-72cjogxz 2467 6 Proliferationsverhalten Proliferationsverhalten NNP cord-015369-72cjogxz 2467 7 und und IN cord-015369-72cjogxz 2467 8 osteogener osteogener NNP cord-015369-72cjogxz 2467 9 Differenzierung Differenzierung NNP cord-015369-72cjogxz 2467 10 . . . cord-015369-72cjogxz 2468 1 Aber Aber NNP cord-015369-72cjogxz 2468 2 bei bei NNP cord-015369-72cjogxz 2468 3 den den NNP cord-015369-72cjogxz 2469 1 18 18 CD cord-015369-72cjogxz 2469 2 Gy Gy NNP cord-015369-72cjogxz 2469 3 - - HYPH cord-015369-72cjogxz 2469 4 Proben Proben NNP cord-015369-72cjogxz 2469 5 nahm nahm NNP cord-015369-72cjogxz 2469 6 die die VBP cord-015369-72cjogxz 2469 7 osteogene osteogene NNP cord-015369-72cjogxz 2469 8 Differenzierungsfähigkeit Differenzierungsfähigkeit NNP cord-015369-72cjogxz 2469 9 signifikant signifikant NN cord-015369-72cjogxz 2469 10 ab ab NN cord-015369-72cjogxz 2469 11 . . . cord-015369-72cjogxz 2470 1 Innerhalb Innerhalb NNP cord-015369-72cjogxz 2470 2 von von NNP cord-015369-72cjogxz 2470 3 2 2 CD cord-015369-72cjogxz 2470 4 Wochen Wochen NNP cord-015369-72cjogxz 2470 5 nahm nahm NNP cord-015369-72cjogxz 2470 6 auch auch NNP cord-015369-72cjogxz 2470 7 die die VBP cord-015369-72cjogxz 2470 8 Proliferationsfähigkeit Proliferationsfähigkeit NNP cord-015369-72cjogxz 2470 9 bei bei NNP cord-015369-72cjogxz 2470 10 den den NN cord-015369-72cjogxz 2470 11 18 18 CD cord-015369-72cjogxz 2470 12 Gy Gy NNP cord-015369-72cjogxz 2470 13 - - HYPH cord-015369-72cjogxz 2470 14 Proben Proben NNP cord-015369-72cjogxz 2470 15 deutlich deutlich NNP cord-015369-72cjogxz 2470 16 ab ab NNP cord-015369-72cjogxz 2470 17 . . . cord-015369-72cjogxz 2471 1 Danach Danach NNP cord-015369-72cjogxz 2471 2 zeigten zeigten NNP cord-015369-72cjogxz 2472 1 sie sie NNP cord-015369-72cjogxz 2473 1 ein ein NNP cord-015369-72cjogxz 2473 2 Proliferationsverhalten Proliferationsverhalten NNP cord-015369-72cjogxz 2473 3 wie wie XX cord-015369-72cjogxz 2473 4 die die VBP cord-015369-72cjogxz 2473 5 anderen anderen NNP cord-015369-72cjogxz 2473 6 Proben Proben NNP cord-015369-72cjogxz 2473 7 . . . cord-015369-72cjogxz 2474 1 Die die VB cord-015369-72cjogxz 2474 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2474 3 dieser dieser JJ cord-015369-72cjogxz 2474 4 aufwändigen aufwändigen NNP cord-015369-72cjogxz 2474 5 interdisziplinären interdisziplinären NNP cord-015369-72cjogxz 2474 6 Kooperation Kooperation NNP cord-015369-72cjogxz 2474 7 von von NNP cord-015369-72cjogxz 2474 8 MKG MKG NNP cord-015369-72cjogxz 2474 9 - - HYPH cord-015369-72cjogxz 2474 10 Chirurgie Chirurgie NNP cord-015369-72cjogxz 2474 11 , , , cord-015369-72cjogxz 2474 12 Anästhesie Anästhesie NNP cord-015369-72cjogxz 2474 13 , , , cord-015369-72cjogxz 2474 14 Strahlentherapie Strahlentherapie NNP cord-015369-72cjogxz 2474 15 und und IN cord-015369-72cjogxz 2474 16 Grundlagenforschung Grundlagenforschung NNP cord-015369-72cjogxz 2474 17 überraschen überraschen NNP cord-015369-72cjogxz 2474 18 , , , cord-015369-72cjogxz 2474 19 da da NNP cord-015369-72cjogxz 2474 20 die die VB cord-015369-72cjogxz 2475 1 MSCs MSCs . cord-015369-72cjogxz 2476 1 i -PRON- PRP cord-015369-72cjogxz 2476 2 m be VBP cord-015369-72cjogxz 2476 3 Knochen Knochen NNP cord-015369-72cjogxz 2477 1 bis bis NNP cord-015369-72cjogxz 2477 2 zu zu XX cord-015369-72cjogxz 2478 1 einer einer NNP cord-015369-72cjogxz 2478 2 bestimmten bestimmten NNP cord-015369-72cjogxz 2478 3 Dosis Dosis NNP cord-015369-72cjogxz 2478 4 der der NNP cord-015369-72cjogxz 2478 5 Bestrahlung Bestrahlung NNP cord-015369-72cjogxz 2478 6 widerstehen widerstehen NNP cord-015369-72cjogxz 2478 7 , , , cord-015369-72cjogxz 2478 8 jedenfalls jedenfalls FW cord-015369-72cjogxz 2478 9 besser besser NNP cord-015369-72cjogxz 2478 10 als als NNP cord-015369-72cjogxz 2478 11 ursprünglich ursprünglich NNP cord-015369-72cjogxz 2478 12 erwartet erwartet NNP cord-015369-72cjogxz 2478 13 . . . cord-015369-72cjogxz 2479 1 Weitere Weitere NNP cord-015369-72cjogxz 2479 2 Untersuchungen Untersuchungen NNP cord-015369-72cjogxz 2479 3 sind sind NNP cord-015369-72cjogxz 2479 4 erforderlich erforderlich NNP cord-015369-72cjogxz 2479 5 , , , cord-015369-72cjogxz 2479 6 um um UH cord-015369-72cjogxz 2479 7 auszuleuchten auszuleuchten NNP cord-015369-72cjogxz 2479 8 , , , cord-015369-72cjogxz 2479 9 ob ob NNP cord-015369-72cjogxz 2479 10 MSCs MSCs NNP cord-015369-72cjogxz 2480 1 durch durch NNP cord-015369-72cjogxz 2480 2 das das NNP cord-015369-72cjogxz 2480 3 umgebende umgebende NNP cord-015369-72cjogxz 2480 4 Gewebe Gewebe NNP cord-015369-72cjogxz 2481 1 oder oder NNP cord-015369-72cjogxz 2482 1 ihre ihre NNP cord-015369-72cjogxz 2482 2 Nische Nische NNP cord-015369-72cjogxz 2482 3 etwa etwa NNP cord-015369-72cjogxz 2482 4 geschützt geschützt VBN cord-015369-72cjogxz 2483 1 sind sind NNP cord-015369-72cjogxz 2484 1 oder oder NNP cord-015369-72cjogxz 2484 2 ob ob NNP cord-015369-72cjogxz 2484 3 doch doch NNP cord-015369-72cjogxz 2485 1 periphere periphere NNP cord-015369-72cjogxz 2485 2 MSCs MSCs NNP cord-015369-72cjogxz 2485 3 neu neu NNP cord-015369-72cjogxz 2485 4 einwandern einwandern NNP cord-015369-72cjogxz 2485 5 und und IN cord-015369-72cjogxz 2485 6 damit damit NNP cord-015369-72cjogxz 2485 7 die die VBP cord-015369-72cjogxz 2485 8 Knochenfunktion Knochenfunktion NNP cord-015369-72cjogxz 2485 9 aufrecht aufrecht NN cord-015369-72cjogxz 2485 10 erhalten erhalten NNP cord-015369-72cjogxz 2485 11 werden werden NNP cord-015369-72cjogxz 2485 12 kann kann NNP cord-015369-72cjogxz 2485 13 . . . cord-015369-72cjogxz 2486 1 Funding funding NN cord-015369-72cjogxz 2486 2 : : : cord-015369-72cjogxz 2487 1 OeNB OeNB NNP cord-015369-72cjogxz 2487 2 - - HYPH cord-015369-72cjogxz 2487 3 Jubiläumsfondsprojekt Jubiläumsfondsprojekt NNP cord-015369-72cjogxz 2487 4 Nr Nr NNP cord-015369-72cjogxz 2487 5 . . . cord-015369-72cjogxz 2488 1 12246 12246 CD cord-015369-72cjogxz 2488 2 . . . cord-015369-72cjogxz 2489 1 Background background NN cord-015369-72cjogxz 2489 2 . . . cord-015369-72cjogxz 2490 1 Gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 2490 2 reflux reflux NN cord-015369-72cjogxz 2490 3 causes cause VBZ cord-015369-72cjogxz 2490 4 dysfunction dysfunction NN cord-015369-72cjogxz 2490 5 of of IN cord-015369-72cjogxz 2490 6 the the DT cord-015369-72cjogxz 2490 7 lower low JJR cord-015369-72cjogxz 2490 8 esophageal esophageal JJ cord-015369-72cjogxz 2490 9 sphincter sphincter NN cord-015369-72cjogxz 2490 10 ( ( -LRB- cord-015369-72cjogxz 2490 11 LES LES NNP cord-015369-72cjogxz 2490 12 ) ) -RRB- cord-015369-72cjogxz 2490 13 and and CC cord-015369-72cjogxz 2490 14 columnar columnar JJ cord-015369-72cjogxz 2490 15 lined line VBN cord-015369-72cjogxz 2490 16 esophagus esophagu NNS cord-015369-72cjogxz 2490 17 ( ( -LRB- cord-015369-72cjogxz 2490 18 CLE CLE NNP cord-015369-72cjogxz 2490 19 ) ) -RRB- cord-015369-72cjogxz 2490 20 resulting result VBG cord-015369-72cjogxz 2490 21 in in IN cord-015369-72cjogxz 2490 22 gastric gastric JJ cord-015369-72cjogxz 2490 23 appearance appearance NN cord-015369-72cjogxz 2490 24 : : : cord-015369-72cjogxz 2490 25 this this DT cord-015369-72cjogxz 2490 26 is be VBZ cord-015369-72cjogxz 2490 27 the the DT cord-015369-72cjogxz 2490 28 dilated dilated JJ cord-015369-72cjogxz 2490 29 end end NN cord-015369-72cjogxz 2490 30 stage stage NN cord-015369-72cjogxz 2490 31 esophagus esophagus NN cord-015369-72cjogxz 2490 32 ( ( -LRB- cord-015369-72cjogxz 2490 33 DESE DESE NNP cord-015369-72cjogxz 2490 34 ¼ ¼ NN cord-015369-72cjogxz 2490 35 CLE CLE NNP cord-015369-72cjogxz 2490 36 within within IN cord-015369-72cjogxz 2490 37 endoscopically endoscopically RB cord-015369-72cjogxz 2490 38 visible visible JJ cord-015369-72cjogxz 2490 39 gastric gastric JJ cord-015369-72cjogxz 2490 40 folds fold NNS cord-015369-72cjogxz 2490 41 interposed interpose VBN cord-015369-72cjogxz 2490 42 between between IN cord-015369-72cjogxz 2490 43 squamous squamous JJ cord-015369-72cjogxz 2490 44 epithelium epithelium NN cord-015369-72cjogxz 2490 45 and and CC cord-015369-72cjogxz 2490 46 oxyntic oxyntic JJ cord-015369-72cjogxz 2490 47 mucosa mucosa NN cord-015369-72cjogxz 2490 48 of of IN cord-015369-72cjogxz 2490 49 the the DT cord-015369-72cjogxz 2490 50 proximal proximal JJ cord-015369-72cjogxz 2490 51 stomach stomach NN cord-015369-72cjogxz 2490 52 ) ) -RRB- cord-015369-72cjogxz 2490 53 . . . cord-015369-72cjogxz 2491 1 We -PRON- PRP cord-015369-72cjogxz 2491 2 report report VBP cord-015369-72cjogxz 2491 3 intermediate intermediate JJ cord-015369-72cjogxz 2491 4 follow follow NN cord-015369-72cjogxz 2491 5 - - HYPH cord-015369-72cjogxz 2491 6 up up NN cord-015369-72cjogxz 2491 7 data datum NNS cord-015369-72cjogxz 2491 8 of of IN cord-015369-72cjogxz 2491 9 patients patient NNS cord-015369-72cjogxz 2491 10 who who WP cord-015369-72cjogxz 2491 11 underwent undergo VBD cord-015369-72cjogxz 2491 12 modified modify VBN cord-015369-72cjogxz 2491 13 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2491 14 Nissen Nissen NNP cord-015369-72cjogxz 2491 15 fundoplication fundoplication NN cord-015369-72cjogxz 2491 16 ( ( -LRB- cord-015369-72cjogxz 2491 17 LNF LNF NNP cord-015369-72cjogxz 2491 18 ) ) -RRB- cord-015369-72cjogxz 2491 19 for for IN cord-015369-72cjogxz 2491 20 gastro gastro JJ cord-015369-72cjogxz 2491 21 - - JJ cord-015369-72cjogxz 2491 22 esophageal esophageal JJ cord-015369-72cjogxz 2491 23 reflux reflux NN cord-015369-72cjogxz 2491 24 disease disease NN cord-015369-72cjogxz 2491 25 ( ( -LRB- cord-015369-72cjogxz 2491 26 GERD GERD NNP cord-015369-72cjogxz 2491 27 ) ) -RRB- cord-015369-72cjogxz 2491 28 with with IN cord-015369-72cjogxz 2491 29 fundic fundic NNP cord-015369-72cjogxz 2491 30 wrap wrap NN cord-015369-72cjogxz 2491 31 placement placement NN cord-015369-72cjogxz 2491 32 around around IN cord-015369-72cjogxz 2491 33 the the DT cord-015369-72cjogxz 2491 34 DESE DESE NNPS cord-015369-72cjogxz 2491 35 . . . cord-015369-72cjogxz 2492 1 Methods method NNS cord-015369-72cjogxz 2492 2 . . . cord-015369-72cjogxz 2493 1 Twenty twenty CD cord-015369-72cjogxz 2493 2 - - HYPH cord-015369-72cjogxz 2493 3 nine nine CD cord-015369-72cjogxz 2493 4 GERD GERD NNP cord-015369-72cjogxz 2493 5 patients patient NNS cord-015369-72cjogxz 2493 6 [ [ -LRB- cord-015369-72cjogxz 2493 7 age age NN cord-015369-72cjogxz 2493 8 52.9 52.9 CD cord-015369-72cjogxz 2493 9 ( ( -LRB- cord-015369-72cjogxz 2493 10 27.6 27.6 CD cord-015369-72cjogxz 2493 11 - - HYPH cord-015369-72cjogxz 2493 12 73.6 73.6 CD cord-015369-72cjogxz 2493 13 ) ) -RRB- cord-015369-72cjogxz 2493 14 , , , cord-015369-72cjogxz 2493 15 18 18 CD cord-015369-72cjogxz 2493 16 female female JJ cord-015369-72cjogxz 2493 17 ) ) -RRB- cord-015369-72cjogxz 2493 18 ] ] -RRB- cord-015369-72cjogxz 2493 19 underwent undergo VBN cord-015369-72cjogxz 2493 20 assessment assessment NN cord-015369-72cjogxz 2493 21 of of IN cord-015369-72cjogxz 2493 22 quality quality NN cord-015369-72cjogxz 2493 23 of of IN cord-015369-72cjogxz 2493 24 life life NN cord-015369-72cjogxz 2493 25 , , , cord-015369-72cjogxz 2493 26 endoscopy endoscopy NN cord-015369-72cjogxz 2493 27 with with IN cord-015369-72cjogxz 2493 28 multilevel multilevel JJ cord-015369-72cjogxz 2493 29 biopsies biopsy NNS cord-015369-72cjogxz 2493 30 from from IN cord-015369-72cjogxz 2493 31 the the DT cord-015369-72cjogxz 2493 32 esophagogastric esophagogastric NNP cord-015369-72cjogxz 2493 33 junction junction NN cord-015369-72cjogxz 2493 34 ( ( -LRB- cord-015369-72cjogxz 2493 35 for for IN cord-015369-72cjogxz 2493 36 assessment assessment NN cord-015369-72cjogxz 2493 37 of of IN cord-015369-72cjogxz 2493 38 DESE DESE NNP cord-015369-72cjogxz 2493 39 length length NN cord-015369-72cjogxz 2493 40 ) ) -RRB- cord-015369-72cjogxz 2493 41 , , , cord-015369-72cjogxz 2493 42 esophageal esophageal JJ cord-015369-72cjogxz 2493 43 manometry manometry NN cord-015369-72cjogxz 2493 44 and and CC cord-015369-72cjogxz 2493 45 ( ( -LRB- cord-015369-72cjogxz 2493 46 impedance- impedance- NNS cord-015369-72cjogxz 2493 47 ) ) -RRB- cord-015369-72cjogxz 2494 1 pH ph NN cord-015369-72cjogxz 2494 2 - - HYPH cord-015369-72cjogxz 2494 3 monitoring monitoring NN cord-015369-72cjogxz 2494 4 before before RB cord-015369-72cjogxz 2494 5 and and CC cord-015369-72cjogxz 2494 6 9 9 CD cord-015369-72cjogxz 2494 7 ( ( -LRB- cord-015369-72cjogxz 2494 8 4 4 CD cord-015369-72cjogxz 2494 9 - - SYM cord-015369-72cjogxz 2494 10 19 19 CD cord-015369-72cjogxz 2494 11 ) ) -RRB- cord-015369-72cjogxz 2494 12 months month NNS cord-015369-72cjogxz 2494 13 after after IN cord-015369-72cjogxz 2494 14 LNF LNF NNP cord-015369-72cjogxz 2494 15 ( ( -LRB- cord-015369-72cjogxz 2494 16 þ þ NNP cord-015369-72cjogxz 2494 17 intraoperative intraoperative JJ cord-015369-72cjogxz 2494 18 endoscopy endoscopy NNP cord-015369-72cjogxz 2494 19 ) ) -RRB- cord-015369-72cjogxz 2494 20 . . . cord-015369-72cjogxz 2495 1 The the DT cord-015369-72cjogxz 2495 2 distal distal JJ cord-015369-72cjogxz 2495 3 limit limit NN cord-015369-72cjogxz 2495 4 of of IN cord-015369-72cjogxz 2495 5 the the DT cord-015369-72cjogxz 2495 6 fundic fundic NNP cord-015369-72cjogxz 2495 7 wrap wrap NN cord-015369-72cjogxz 2495 8 was be VBD cord-015369-72cjogxz 2495 9 placed place VBN cord-015369-72cjogxz 2495 10 at at IN cord-015369-72cjogxz 2495 11 the the DT cord-015369-72cjogxz 2495 12 level level NN cord-015369-72cjogxz 2495 13 of of IN cord-015369-72cjogxz 2495 14 the the DT cord-015369-72cjogxz 2495 15 peritoneal peritoneal JJ cord-015369-72cjogxz 2495 16 reflection reflection NN cord-015369-72cjogxz 2495 17 ( ( -LRB- cord-015369-72cjogxz 2495 18 ¼ ¼ NNP cord-015369-72cjogxz 2495 19 anatomic anatomic NNP cord-015369-72cjogxz 2495 20 esophagogastric esophagogastric NNP cord-015369-72cjogxz 2495 21 junction junction NNP cord-015369-72cjogxz 2495 22 ) ) -RRB- cord-015369-72cjogxz 2495 23 and and CC cord-015369-72cjogxz 2495 24 extended extend VBD cord-015369-72cjogxz 2495 25 proximally proximally RB cord-015369-72cjogxz 2495 26 over over IN cord-015369-72cjogxz 2495 27 a a DT cord-015369-72cjogxz 2495 28 length length NN cord-015369-72cjogxz 2495 29 of of IN cord-015369-72cjogxz 2495 30 1.5 1.5 CD cord-015369-72cjogxz 2495 31 cm cm NNS cord-015369-72cjogxz 2495 32 . . . cord-015369-72cjogxz 2496 1 Results result NNS cord-015369-72cjogxz 2496 2 . . . cord-015369-72cjogxz 2497 1 Intraoperative Intraoperative NNP cord-015369-72cjogxz 2497 2 endoscopy endoscopy NN cord-015369-72cjogxz 2497 3 revealed reveal VBD cord-015369-72cjogxz 2497 4 adequate adequate JJ cord-015369-72cjogxz 2497 5 wrap wrap NN cord-015369-72cjogxz 2497 6 placement placement NN cord-015369-72cjogxz 2497 7 in in IN cord-015369-72cjogxz 2497 8 all all DT cord-015369-72cjogxz 2497 9 patients patient NNS cord-015369-72cjogxz 2497 10 . . . cord-015369-72cjogxz 2498 1 Follow follow VB cord-015369-72cjogxz 2498 2 - - HYPH cord-015369-72cjogxz 2498 3 up up RP cord-015369-72cjogxz 2498 4 data datum NNS cord-015369-72cjogxz 2498 5 . . . cord-015369-72cjogxz 2499 1 Background background NN cord-015369-72cjogxz 2499 2 . . . cord-015369-72cjogxz 2500 1 Laparoscopic laparoscopic JJ cord-015369-72cjogxz 2500 2 antireflux antireflux NNP cord-015369-72cjogxz 2500 3 surgery surgery NN cord-015369-72cjogxz 2500 4 is be VBZ cord-015369-72cjogxz 2500 5 a a DT cord-015369-72cjogxz 2500 6 well well RB cord-015369-72cjogxz 2500 7 established establish VBN cord-015369-72cjogxz 2500 8 treatment treatment NN cord-015369-72cjogxz 2500 9 of of IN cord-015369-72cjogxz 2500 10 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 2500 11 reflux reflux NN cord-015369-72cjogxz 2500 12 disease disease NN cord-015369-72cjogxz 2500 13 ( ( -LRB- cord-015369-72cjogxz 2500 14 GERD GERD NNP cord-015369-72cjogxz 2500 15 ) ) -RRB- cord-015369-72cjogxz 2500 16 . . . cord-015369-72cjogxz 2501 1 Persistent persistent JJ cord-015369-72cjogxz 2501 2 or or CC cord-015369-72cjogxz 2501 3 recurrent recurrent JJ cord-015369-72cjogxz 2501 4 reflux reflux NN cord-015369-72cjogxz 2501 5 , , , cord-015369-72cjogxz 2501 6 gas gas NN cord-015369-72cjogxz 2501 7 - - HYPH cord-015369-72cjogxz 2501 8 bloat bloat NN cord-015369-72cjogxz 2501 9 syndrome syndrome NN cord-015369-72cjogxz 2501 10 or or CC cord-015369-72cjogxz 2501 11 dysphagia dysphagia NN cord-015369-72cjogxz 2501 12 may may MD cord-015369-72cjogxz 2501 13 result result VB cord-015369-72cjogxz 2501 14 in in IN cord-015369-72cjogxz 2501 15 repeated repeat VBN cord-015369-72cjogxz 2501 16 surgical surgical JJ cord-015369-72cjogxz 2501 17 treatment treatment NN cord-015369-72cjogxz 2501 18 which which WDT cord-015369-72cjogxz 2501 19 are be VBP cord-015369-72cjogxz 2501 20 at at IN cord-015369-72cjogxz 2501 21 higher high JJR cord-015369-72cjogxz 2501 22 risk risk NN cord-015369-72cjogxz 2501 23 of of IN cord-015369-72cjogxz 2501 24 perioperative perioperative JJ cord-015369-72cjogxz 2501 25 morbidity morbidity NN cord-015369-72cjogxz 2501 26 and and CC cord-015369-72cjogxz 2501 27 mortality mortality NN cord-015369-72cjogxz 2501 28 . . . cord-015369-72cjogxz 2502 1 Methods method NNS cord-015369-72cjogxz 2502 2 . . . cord-015369-72cjogxz 2503 1 From from IN cord-015369-72cjogxz 2503 2 March March NNP cord-015369-72cjogxz 2503 3 1999 1999 CD cord-015369-72cjogxz 2503 4 until until IN cord-015369-72cjogxz 2503 5 April April NNP cord-015369-72cjogxz 2503 6 2008 2008 CD cord-015369-72cjogxz 2503 7 , , , cord-015369-72cjogxz 2503 8 in in IN cord-015369-72cjogxz 2503 9 135 135 CD cord-015369-72cjogxz 2503 10 patients patient NNS cord-015369-72cjogxz 2503 11 antireflux antireflux NNP cord-015369-72cjogxz 2503 12 procedures procedure NNS cord-015369-72cjogxz 2503 13 were be VBD cord-015369-72cjogxz 2503 14 performed perform VBN cord-015369-72cjogxz 2503 15 because because IN cord-015369-72cjogxz 2503 16 of of IN cord-015369-72cjogxz 2503 17 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 2503 18 reflux reflux NN cord-015369-72cjogxz 2503 19 disease disease NN cord-015369-72cjogxz 2503 20 and and CC cord-015369-72cjogxz 2503 21 hiatal hiatal JJ cord-015369-72cjogxz 2503 22 hernia hernia NN cord-015369-72cjogxz 2503 23 . . . cord-015369-72cjogxz 2504 1 In in IN cord-015369-72cjogxz 2504 2 19 19 CD cord-015369-72cjogxz 2504 3 patients patient NNS cord-015369-72cjogxz 2504 4 ( ( -LRB- cord-015369-72cjogxz 2504 5 14 14 CD cord-015369-72cjogxz 2504 6 % % NN cord-015369-72cjogxz 2504 7 ) ) -RRB- cord-015369-72cjogxz 2504 8 of of IN cord-015369-72cjogxz 2504 9 which which WDT cord-015369-72cjogxz 2504 10 7 7 CD cord-015369-72cjogxz 2504 11 patients patient NNS cord-015369-72cjogxz 2504 12 were be VBD cord-015369-72cjogxz 2504 13 male male JJ cord-015369-72cjogxz 2504 14 ( ( -LRB- cord-015369-72cjogxz 2504 15 37 37 CD cord-015369-72cjogxz 2504 16 % % NN cord-015369-72cjogxz 2504 17 ) ) -RRB- cord-015369-72cjogxz 2504 18 repeated repeat VBD cord-015369-72cjogxz 2504 19 antireflux antireflux NNP cord-015369-72cjogxz 2504 20 surgery surgery NN cord-015369-72cjogxz 2504 21 was be VBD cord-015369-72cjogxz 2504 22 necessary necessary JJ cord-015369-72cjogxz 2504 23 . . . cord-015369-72cjogxz 2505 1 Retrospective retrospective JJ cord-015369-72cjogxz 2505 2 data datum NNS cord-015369-72cjogxz 2505 3 collection collection NN cord-015369-72cjogxz 2505 4 was be VBD cord-015369-72cjogxz 2505 5 analysed analyse VBN cord-015369-72cjogxz 2505 6 for for IN cord-015369-72cjogxz 2505 7 postoperative postoperative JJ cord-015369-72cjogxz 2505 8 course course NN cord-015369-72cjogxz 2505 9 , , , cord-015369-72cjogxz 2505 10 perioperative perioperative JJ cord-015369-72cjogxz 2505 11 morbidity morbidity NN cord-015369-72cjogxz 2505 12 and and CC cord-015369-72cjogxz 2505 13 mortality mortality NN cord-015369-72cjogxz 2505 14 after after IN cord-015369-72cjogxz 2505 15 redo redo NN cord-015369-72cjogxz 2505 16 - - HYPH cord-015369-72cjogxz 2505 17 fundoplication fundoplication NN cord-015369-72cjogxz 2505 18 . . . cord-015369-72cjogxz 2506 1 Results result NNS cord-015369-72cjogxz 2506 2 . . . cord-015369-72cjogxz 2507 1 Redo redo VB cord-015369-72cjogxz 2507 2 - - HYPH cord-015369-72cjogxz 2507 3 fundoplications fundoplication NNS cord-015369-72cjogxz 2507 4 were be VBD cord-015369-72cjogxz 2507 5 made make VBN cord-015369-72cjogxz 2507 6 on on IN cord-015369-72cjogxz 2507 7 the the DT cord-015369-72cjogxz 2507 8 ground ground NN cord-015369-72cjogxz 2507 9 of of IN cord-015369-72cjogxz 2507 10 recurrent recurrent JJ cord-015369-72cjogxz 2507 11 reflux reflux NN cord-015369-72cjogxz 2507 12 ( ( -LRB- cord-015369-72cjogxz 2507 13 n n NN cord-015369-72cjogxz 2507 14 ¼ ¼ NNP cord-015369-72cjogxz 2507 15 7 7 CD cord-015369-72cjogxz 2507 16 ) ) -RRB- cord-015369-72cjogxz 2507 17 , , , cord-015369-72cjogxz 2507 18 herniation herniation NN cord-015369-72cjogxz 2507 19 of of IN cord-015369-72cjogxz 2507 20 the the DT cord-015369-72cjogxz 2507 21 wrap wrap NN cord-015369-72cjogxz 2507 22 ( ( -LRB- cord-015369-72cjogxz 2507 23 n n NN cord-015369-72cjogxz 2507 24 ¼ ¼ NNP cord-015369-72cjogxz 2507 25 9 9 CD cord-015369-72cjogxz 2507 26 ) ) -RRB- cord-015369-72cjogxz 2507 27 or or CC cord-015369-72cjogxz 2507 28 scarred scarred JJ cord-015369-72cjogxz 2507 29 adhesions adhesion NNS cord-015369-72cjogxz 2507 30 and and CC cord-015369-72cjogxz 2507 31 dysphagia dysphagia NNP cord-015369-72cjogxz 2507 32 ( ( -LRB- cord-015369-72cjogxz 2507 33 n n NN cord-015369-72cjogxz 2507 34 ¼ ¼ NNP cord-015369-72cjogxz 2507 35 3 3 CD cord-015369-72cjogxz 2507 36 ) ) -RRB- cord-015369-72cjogxz 2507 37 . . . cord-015369-72cjogxz 2508 1 All all DT cord-015369-72cjogxz 2508 2 procedures procedure NNS cord-015369-72cjogxz 2508 3 were be VBD cord-015369-72cjogxz 2508 4 completed complete VBN cord-015369-72cjogxz 2508 5 laparoscopically laparoscopically RB cord-015369-72cjogxz 2508 6 . . . cord-015369-72cjogxz 2509 1 The the DT cord-015369-72cjogxz 2509 2 mean mean JJ cord-015369-72cjogxz 2509 3 operation operation NN cord-015369-72cjogxz 2509 4 time time NN cord-015369-72cjogxz 2509 5 was be VBD cord-015369-72cjogxz 2509 6 140 140 CD cord-015369-72cjogxz 2509 7 min min NN cord-015369-72cjogxz 2509 8 ( ( -LRB- cord-015369-72cjogxz 2509 9 90 90 CD cord-015369-72cjogxz 2509 10 - - SYM cord-015369-72cjogxz 2509 11 285 285 CD cord-015369-72cjogxz 2509 12 min min NN cord-015369-72cjogxz 2509 13 ) ) -RRB- cord-015369-72cjogxz 2509 14 . . . cord-015369-72cjogxz 2510 1 In in IN cord-015369-72cjogxz 2510 2 15 15 CD cord-015369-72cjogxz 2510 3 patients patient NNS cord-015369-72cjogxz 2510 4 360 360 CD cord-015369-72cjogxz 2510 5 Nissen Nissen NNP cord-015369-72cjogxz 2510 6 and and CC cord-015369-72cjogxz 2510 7 in in IN cord-015369-72cjogxz 2510 8 4 4 CD cord-015369-72cjogxz 2510 9 patients patient NNS cord-015369-72cjogxz 2510 10 270 270 CD cord-015369-72cjogxz 2510 11 Toupet Toupet NNP cord-015369-72cjogxz 2510 12 fundoplication fundoplication NN cord-015369-72cjogxz 2510 13 were be VBD cord-015369-72cjogxz 2510 14 performed perform VBN cord-015369-72cjogxz 2510 15 . . . cord-015369-72cjogxz 2511 1 Intraoperatively intraoperatively RB cord-015369-72cjogxz 2511 2 there there RB cord-015369-72cjogxz 2511 3 occured occur VBD cord-015369-72cjogxz 2511 4 in in IN cord-015369-72cjogxz 2511 5 3 3 CD cord-015369-72cjogxz 2511 6 patients patient NNS cord-015369-72cjogxz 2511 7 lesions lesion NNS cord-015369-72cjogxz 2511 8 of of IN cord-015369-72cjogxz 2511 9 the the DT cord-015369-72cjogxz 2511 10 wrap wrap NN cord-015369-72cjogxz 2511 11 and and CC cord-015369-72cjogxz 2511 12 in in IN cord-015369-72cjogxz 2511 13 one one CD cord-015369-72cjogxz 2511 14 patient patient NN cord-015369-72cjogxz 2511 15 a a DT cord-015369-72cjogxz 2511 16 lesion lesion NN cord-015369-72cjogxz 2511 17 of of IN cord-015369-72cjogxz 2511 18 the the DT cord-015369-72cjogxz 2511 19 pleura pleura NN cord-015369-72cjogxz 2511 20 . . . cord-015369-72cjogxz 2512 1 In in IN cord-015369-72cjogxz 2512 2 one one CD cord-015369-72cjogxz 2512 3 patient patient NN cord-015369-72cjogxz 2512 4 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2512 5 revisions revision NNS cord-015369-72cjogxz 2512 6 with with IN cord-015369-72cjogxz 2512 7 suture suture NN cord-015369-72cjogxz 2512 8 was be VBD cord-015369-72cjogxz 2512 9 necessary necessary JJ cord-015369-72cjogxz 2512 10 . . . cord-015369-72cjogxz 2513 1 There there EX cord-015369-72cjogxz 2513 2 were be VBD cord-015369-72cjogxz 2513 3 no no DT cord-015369-72cjogxz 2513 4 postoperative postoperative JJ cord-015369-72cjogxz 2513 5 in in IN cord-015369-72cjogxz 2513 6 - - HYPH cord-015369-72cjogxz 2513 7 hospital hospital NN cord-015369-72cjogxz 2513 8 deaths death NNS cord-015369-72cjogxz 2513 9 . . . cord-015369-72cjogxz 2514 1 The the DT cord-015369-72cjogxz 2514 2 median median JJ cord-015369-72cjogxz 2514 3 length length NN cord-015369-72cjogxz 2514 4 of of IN cord-015369-72cjogxz 2514 5 hospital hospital NN cord-015369-72cjogxz 2514 6 stay stay NN cord-015369-72cjogxz 2514 7 was be VBD cord-015369-72cjogxz 2514 8 7 7 CD cord-015369-72cjogxz 2514 9 days day NNS cord-015369-72cjogxz 2514 10 ( ( -LRB- cord-015369-72cjogxz 2514 11 3 3 CD cord-015369-72cjogxz 2514 12 - - SYM cord-015369-72cjogxz 2514 13 20 20 CD cord-015369-72cjogxz 2514 14 days day NNS cord-015369-72cjogxz 2514 15 ) ) -RRB- cord-015369-72cjogxz 2514 16 . . . cord-015369-72cjogxz 2515 1 At at IN cord-015369-72cjogxz 2515 2 discharge discharge NN cord-015369-72cjogxz 2515 3 no no DT cord-015369-72cjogxz 2515 4 patient patient NN cord-015369-72cjogxz 2515 5 had have VBD cord-015369-72cjogxz 2515 6 relevant relevant JJ cord-015369-72cjogxz 2515 7 symptoms symptom NNS cord-015369-72cjogxz 2515 8 of of IN cord-015369-72cjogxz 2515 9 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 2515 10 reflux reflux NN cord-015369-72cjogxz 2515 11 . . . cord-015369-72cjogxz 2516 1 Conclusions conclusion NNS cord-015369-72cjogxz 2516 2 . . . cord-015369-72cjogxz 2517 1 Reoperative reoperative JJ cord-015369-72cjogxz 2517 2 surgery surgery NN cord-015369-72cjogxz 2517 3 after after IN cord-015369-72cjogxz 2517 4 fundoplication fundoplication NN cord-015369-72cjogxz 2517 5 is be VBZ cord-015369-72cjogxz 2517 6 known know VBN cord-015369-72cjogxz 2517 7 to to TO cord-015369-72cjogxz 2517 8 be be VB cord-015369-72cjogxz 2517 9 very very RB cord-015369-72cjogxz 2517 10 technical technical JJ cord-015369-72cjogxz 2517 11 challenging challenging NN cord-015369-72cjogxz 2517 12 because because IN cord-015369-72cjogxz 2517 13 of of IN cord-015369-72cjogxz 2517 14 scarred scarred JJ cord-015369-72cjogxz 2517 15 tissue tissue NN cord-015369-72cjogxz 2517 16 . . . cord-015369-72cjogxz 2518 1 So so CC cord-015369-72cjogxz 2518 2 it -PRON- PRP cord-015369-72cjogxz 2518 3 is be VBZ cord-015369-72cjogxz 2518 4 associated associate VBN cord-015369-72cjogxz 2518 5 with with IN cord-015369-72cjogxz 2518 6 higher high JJR cord-015369-72cjogxz 2518 7 morbidity morbidity NN cord-015369-72cjogxz 2518 8 and and CC cord-015369-72cjogxz 2518 9 mortality mortality NN cord-015369-72cjogxz 2518 10 . . . cord-015369-72cjogxz 2519 1 In in IN cord-015369-72cjogxz 2519 2 our -PRON- PRP$ cord-015369-72cjogxz 2519 3 case case NN cord-015369-72cjogxz 2519 4 study study NN cord-015369-72cjogxz 2519 5 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2519 6 redo redo NN cord-015369-72cjogxz 2519 7 - - HYPH cord-015369-72cjogxz 2519 8 fundoplication fundoplication NN cord-015369-72cjogxz 2519 9 was be VBD cord-015369-72cjogxz 2519 10 feasible feasible JJ cord-015369-72cjogxz 2519 11 and and CC cord-015369-72cjogxz 2519 12 with with IN cord-015369-72cjogxz 2519 13 low low JJ cord-015369-72cjogxz 2519 14 incidence incidence NN cord-015369-72cjogxz 2519 15 of of IN cord-015369-72cjogxz 2519 16 perioperative perioperative JJ cord-015369-72cjogxz 2519 17 morbidity morbidity NN cord-015369-72cjogxz 2519 18 and and CC cord-015369-72cjogxz 2519 19 no no DT cord-015369-72cjogxz 2519 20 mortality mortality NN cord-015369-72cjogxz 2519 21 . . . cord-015369-72cjogxz 2520 1 Background background NN cord-015369-72cjogxz 2520 2 . . . cord-015369-72cjogxz 2521 1 Giant giant JJ cord-015369-72cjogxz 2521 2 leiomyomas leiomyoma NNS cord-015369-72cjogxz 2521 3 of of IN cord-015369-72cjogxz 2521 4 the the DT cord-015369-72cjogxz 2521 5 esophagus esophagus NN cord-015369-72cjogxz 2521 6 bear bear VBP cord-015369-72cjogxz 2521 7 the the DT cord-015369-72cjogxz 2521 8 risk risk NN cord-015369-72cjogxz 2521 9 of of IN cord-015369-72cjogxz 2521 10 malignancy malignancy NN cord-015369-72cjogxz 2521 11 . . . cord-015369-72cjogxz 2522 1 Treatment treatment NN cord-015369-72cjogxz 2522 2 is be VBZ cord-015369-72cjogxz 2522 3 a a DT cord-015369-72cjogxz 2522 4 function function NN cord-015369-72cjogxz 2522 5 of of IN cord-015369-72cjogxz 2522 6 size size NN cord-015369-72cjogxz 2522 7 , , , cord-015369-72cjogxz 2522 8 small small JJ cord-015369-72cjogxz 2522 9 tumors tumor NNS cord-015369-72cjogxz 2522 10 might may MD cord-015369-72cjogxz 2522 11 be be VB cord-015369-72cjogxz 2522 12 removed remove VBN cord-015369-72cjogxz 2522 13 endoscopically endoscopically RB cord-015369-72cjogxz 2522 14 with with IN cord-015369-72cjogxz 2522 15 the the DT cord-015369-72cjogxz 2522 16 ever ever RB cord-015369-72cjogxz 2522 17 present present JJ cord-015369-72cjogxz 2522 18 risk risk NN cord-015369-72cjogxz 2522 19 of of IN cord-015369-72cjogxz 2522 20 hemorrhage hemorrhage NN cord-015369-72cjogxz 2522 21 . . . cord-015369-72cjogxz 2523 1 Large large JJ cord-015369-72cjogxz 2523 2 tumors tumor NNS cord-015369-72cjogxz 2523 3 require require VBP cord-015369-72cjogxz 2523 4 surgery surgery NN cord-015369-72cjogxz 2523 5 , , , cord-015369-72cjogxz 2523 6 the the DT cord-015369-72cjogxz 2523 7 approach approach NN cord-015369-72cjogxz 2523 8 depending depend VBG cord-015369-72cjogxz 2523 9 on on IN cord-015369-72cjogxz 2523 10 the the DT cord-015369-72cjogxz 2523 11 tumor tumor NN cord-015369-72cjogxz 2523 12 site site NN cord-015369-72cjogxz 2523 13 and and CC cord-015369-72cjogxz 2523 14 size size NN cord-015369-72cjogxz 2523 15 . . . cord-015369-72cjogxz 2524 1 Methods method NNS cord-015369-72cjogxz 2524 2 . . . cord-015369-72cjogxz 2525 1 We -PRON- PRP cord-015369-72cjogxz 2525 2 report report VBP cord-015369-72cjogxz 2525 3 on on IN cord-015369-72cjogxz 2525 4 a a DT cord-015369-72cjogxz 2525 5 symptomatic symptomatic JJ cord-015369-72cjogxz 2525 6 male male JJ cord-015369-72cjogxz 2525 7 patient patient NN cord-015369-72cjogxz 2525 8 ( ( -LRB- cord-015369-72cjogxz 2525 9 45a 45a NNS cord-015369-72cjogxz 2525 10 ) ) -RRB- cord-015369-72cjogxz 2525 11 suffering suffer VBG cord-015369-72cjogxz 2525 12 from from IN cord-015369-72cjogxz 2525 13 a a DT cord-015369-72cjogxz 2525 14 giant giant JJ cord-015369-72cjogxz 2525 15 leiomyoma leiomyoma NNP cord-015369-72cjogxz 2525 16 ( ( -LRB- cord-015369-72cjogxz 2525 17 12 12 CD cord-015369-72cjogxz 2525 18 Â â CD cord-015369-72cjogxz 2525 19 4 4 CD cord-015369-72cjogxz 2525 20 cm cm NNS cord-015369-72cjogxz 2525 21 ) ) -RRB- cord-015369-72cjogxz 2525 22 in in IN cord-015369-72cjogxz 2525 23 the the DT cord-015369-72cjogxz 2525 24 esophagus esophagus NN cord-015369-72cjogxz 2525 25 . . . cord-015369-72cjogxz 2526 1 Preoperative Preoperative NNP cord-015369-72cjogxz 2526 2 testing testing NN cord-015369-72cjogxz 2526 3 comprising comprise VBG cord-015369-72cjogxz 2526 4 contrast contrast NN cord-015369-72cjogxz 2526 5 swallow swallow NN cord-015369-72cjogxz 2526 6 , , , cord-015369-72cjogxz 2526 7 endoscopy endoscopy NN cord-015369-72cjogxz 2526 8 , , , cord-015369-72cjogxz 2526 9 endoscopic endoscopic NN cord-015369-72cjogxz 2526 10 ultrasound ultrasound NN cord-015369-72cjogxz 2526 11 , , , cord-015369-72cjogxz 2526 12 CT CT NNP cord-015369-72cjogxz 2526 13 , , , cord-015369-72cjogxz 2526 14 and and CC cord-015369-72cjogxz 2526 15 true true RB cord-015369-72cjogxz 2526 16 - - HYPH cord-015369-72cjogxz 2526 17 cut cut VBN cord-015369-72cjogxz 2526 18 biopsy biopsy NN cord-015369-72cjogxz 2526 19 confirmed confirm VBD cord-015369-72cjogxz 2526 20 the the DT cord-015369-72cjogxz 2526 21 diagnosis diagnosis NN cord-015369-72cjogxz 2526 22 . . . cord-015369-72cjogxz 2527 1 Patient Patient NNP cord-015369-72cjogxz 2527 2 was be VBD cord-015369-72cjogxz 2527 3 found find VBN cord-015369-72cjogxz 2527 4 eligible eligible JJ cord-015369-72cjogxz 2527 5 for for IN cord-015369-72cjogxz 2527 6 thoraco thoraco NNS cord-015369-72cjogxz 2527 7 - - HYPH cord-015369-72cjogxz 2527 8 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2527 9 esophageal esophageal JJ cord-015369-72cjogxz 2527 10 resection resection NN cord-015369-72cjogxz 2527 11 . . . cord-015369-72cjogxz 2528 1 Results result NNS cord-015369-72cjogxz 2528 2 . . . cord-015369-72cjogxz 2529 1 The the DT cord-015369-72cjogxz 2529 2 minimal minimal JJ cord-015369-72cjogxz 2529 3 invasive invasive JJ cord-015369-72cjogxz 2529 4 procedure procedure NN cord-015369-72cjogxz 2529 5 was be VBD cord-015369-72cjogxz 2529 6 carried carry VBN cord-015369-72cjogxz 2529 7 out out RP cord-015369-72cjogxz 2529 8 with with IN cord-015369-72cjogxz 2529 9 the the DT cord-015369-72cjogxz 2529 10 patient patient NN cord-015369-72cjogxz 2529 11 in in IN cord-015369-72cjogxz 2529 12 the the DT cord-015369-72cjogxz 2529 13 left left JJ cord-015369-72cjogxz 2529 14 - - HYPH cord-015369-72cjogxz 2529 15 lateral lateral JJ cord-015369-72cjogxz 2529 16 position position NN cord-015369-72cjogxz 2529 17 . . . cord-015369-72cjogxz 2530 1 Thoracoscopic Thoracoscopic NNP cord-015369-72cjogxz 2530 2 resec- resec- NN cord-015369-72cjogxz 2530 3 tion tion NN cord-015369-72cjogxz 2530 4 utilized utilize VBD cord-015369-72cjogxz 2530 5 four four CD cord-015369-72cjogxz 2530 6 trocars trocar NNS cord-015369-72cjogxz 2530 7 . . . cord-015369-72cjogxz 2531 1 The the DT cord-015369-72cjogxz 2531 2 azygos azygo NNS cord-015369-72cjogxz 2531 3 vein vein NN cord-015369-72cjogxz 2531 4 was be VBD cord-015369-72cjogxz 2531 5 divided divide VBN cord-015369-72cjogxz 2531 6 with with IN cord-015369-72cjogxz 2531 7 an an DT cord-015369-72cjogxz 2531 8 Endo Endo NNP cord-015369-72cjogxz 2531 9 - - HYPH cord-015369-72cjogxz 2531 10 GIA GIA NNP cord-015369-72cjogxz 2531 11 . . . cord-015369-72cjogxz 2532 1 After after IN cord-015369-72cjogxz 2532 2 transection transection NN cord-015369-72cjogxz 2532 3 of of IN cord-015369-72cjogxz 2532 4 the the DT cord-015369-72cjogxz 2532 5 esophagus esophagus NN cord-015369-72cjogxz 2532 6 at at IN cord-015369-72cjogxz 2532 7 the the DT cord-015369-72cjogxz 2532 8 level level NN cord-015369-72cjogxz 2532 9 of of IN cord-015369-72cjogxz 2532 10 the the DT cord-015369-72cjogxz 2532 11 thoracic thoracic JJ cord-015369-72cjogxz 2532 12 apex apex NN cord-015369-72cjogxz 2532 13 the the DT cord-015369-72cjogxz 2532 14 table table NN cord-015369-72cjogxz 2532 15 was be VBD cord-015369-72cjogxz 2532 16 tilted tilt VBN cord-015369-72cjogxz 2532 17 to to IN cord-015369-72cjogxz 2532 18 the the DT cord-015369-72cjogxz 2532 19 right right NN cord-015369-72cjogxz 2532 20 to to TO cord-015369-72cjogxz 2532 21 perform perform VB cord-015369-72cjogxz 2532 22 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2532 23 preparation preparation NN cord-015369-72cjogxz 2532 24 of of IN cord-015369-72cjogxz 2532 25 the the DT cord-015369-72cjogxz 2532 26 gastric gastric JJ cord-015369-72cjogxz 2532 27 conduit conduit NN cord-015369-72cjogxz 2532 28 . . . cord-015369-72cjogxz 2533 1 Thereafter thereafter RB cord-015369-72cjogxz 2533 2 the the DT cord-015369-72cjogxz 2533 3 stomach stomach NN cord-015369-72cjogxz 2533 4 was be VBD cord-015369-72cjogxz 2533 5 pulled pull VBN cord-015369-72cjogxz 2533 6 up up RP cord-015369-72cjogxz 2533 7 into into IN cord-015369-72cjogxz 2533 8 the the DT cord-015369-72cjogxz 2533 9 thorax thorax NN cord-015369-72cjogxz 2533 10 . . . cord-015369-72cjogxz 2534 1 Enlargement enlargement NN cord-015369-72cjogxz 2534 2 of of IN cord-015369-72cjogxz 2534 3 trocar trocar NN cord-015369-72cjogxz 2534 4 sites site NNS cord-015369-72cjogxz 2534 5 was be VBD cord-015369-72cjogxz 2534 6 necessary necessary JJ cord-015369-72cjogxz 2534 7 for for IN cord-015369-72cjogxz 2534 8 specimen specimen NN cord-015369-72cjogxz 2534 9 retrieval retrieval NN cord-015369-72cjogxz 2534 10 . . . cord-015369-72cjogxz 2535 1 Intra intra JJ cord-015369-72cjogxz 2535 2 - - JJ cord-015369-72cjogxz 2535 3 thoracic thoracic JJ cord-015369-72cjogxz 2535 4 circular circular JJ cord-015369-72cjogxz 2535 5 stapled staple VBN cord-015369-72cjogxz 2535 6 anastomosis anastomosis NN cord-015369-72cjogxz 2535 7 was be VBD cord-015369-72cjogxz 2535 8 done do VBN cord-015369-72cjogxz 2535 9 transorally transorally RB cord-015369-72cjogxz 2536 1 ( ( -LRB- cord-015369-72cjogxz 2536 2 Orvil Orvil NNP cord-015369-72cjogxz 2536 3 + + CC cord-015369-72cjogxz 2536 4 , , , cord-015369-72cjogxz 2536 5 Covidien Covidien NNP cord-015369-72cjogxz 2536 6 ) ) -RRB- cord-015369-72cjogxz 2536 7 . . . cord-015369-72cjogxz 2537 1 Procedural procedural JJ cord-015369-72cjogxz 2537 2 time time NN cord-015369-72cjogxz 2537 3 lasted last VBD cord-015369-72cjogxz 2537 4 in in IN cord-015369-72cjogxz 2537 5 total total JJ cord-015369-72cjogxz 2537 6 seven seven CD cord-015369-72cjogxz 2537 7 hours hour NNS cord-015369-72cjogxz 2537 8 . . . cord-015369-72cjogxz 2538 1 Blood blood NN cord-015369-72cjogxz 2538 2 loss loss NN cord-015369-72cjogxz 2538 3 yielded yield VBD cord-015369-72cjogxz 2538 4 insignificant insignificant JJ cord-015369-72cjogxz 2538 5 and and CC cord-015369-72cjogxz 2538 6 no no DT cord-015369-72cjogxz 2538 7 intraoperative intraoperative JJ cord-015369-72cjogxz 2538 8 complication complication NN cord-015369-72cjogxz 2538 9 was be VBD cord-015369-72cjogxz 2538 10 observed observe VBN cord-015369-72cjogxz 2538 11 . . . cord-015369-72cjogxz 2539 1 Histology histology NN cord-015369-72cjogxz 2539 2 yielded yield VBD cord-015369-72cjogxz 2539 3 no no DT cord-015369-72cjogxz 2539 4 malignancy malignancy NN cord-015369-72cjogxz 2539 5 . . . cord-015369-72cjogxz 2540 1 Patient Patient NNP cord-015369-72cjogxz 2540 2 started start VBD cord-015369-72cjogxz 2540 3 with with IN cord-015369-72cjogxz 2540 4 oral oral JJ cord-015369-72cjogxz 2540 5 diet diet NN cord-015369-72cjogxz 2540 6 on on IN cord-015369-72cjogxz 2540 7 postoperative postoperative JJ cord-015369-72cjogxz 2540 8 day day NN cord-015369-72cjogxz 2540 9 2 2 CD cord-015369-72cjogxz 2540 10 and and CC cord-015369-72cjogxz 2540 11 was be VBD cord-015369-72cjogxz 2540 12 discharged discharge VBN cord-015369-72cjogxz 2540 13 on on IN cord-015369-72cjogxz 2540 14 day day NN cord-015369-72cjogxz 2540 15 18 18 CD cord-015369-72cjogxz 2540 16 . . . cord-015369-72cjogxz 2541 1 Follow follow VB cord-015369-72cjogxz 2541 2 - - HYPH cord-015369-72cjogxz 2541 3 up up NN cord-015369-72cjogxz 2541 4 after after IN cord-015369-72cjogxz 2541 5 three three CD cord-015369-72cjogxz 2541 6 months month NNS cord-015369-72cjogxz 2541 7 was be VBD cord-015369-72cjogxz 2541 8 uneventful uneventful JJ cord-015369-72cjogxz 2541 9 . . . cord-015369-72cjogxz 2542 1 Conclusions conclusion NNS cord-015369-72cjogxz 2542 2 . . . cord-015369-72cjogxz 2543 1 Giant giant JJ cord-015369-72cjogxz 2543 2 leiomyoma leiomyoma NN cord-015369-72cjogxz 2543 3 of of IN cord-015369-72cjogxz 2543 4 the the DT cord-015369-72cjogxz 2543 5 esophagus esophagus NN cord-015369-72cjogxz 2543 6 require require VBP cord-015369-72cjogxz 2543 7 surgical surgical JJ cord-015369-72cjogxz 2543 8 resection resection NN cord-015369-72cjogxz 2543 9 . . . cord-015369-72cjogxz 2544 1 We -PRON- PRP cord-015369-72cjogxz 2544 2 present present VBP cord-015369-72cjogxz 2544 3 our -PRON- PRP$ cord-015369-72cjogxz 2544 4 technique technique NN cord-015369-72cjogxz 2544 5 for for IN cord-015369-72cjogxz 2544 6 thoraco thoraco NNS cord-015369-72cjogxz 2544 7 - - HYPH cord-015369-72cjogxz 2544 8 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2544 9 esophageal esophageal JJ cord-015369-72cjogxz 2544 10 resection resection NN cord-015369-72cjogxz 2544 11 . . . cord-015369-72cjogxz 2545 1 Background background NN cord-015369-72cjogxz 2545 2 . . . cord-015369-72cjogxz 2546 1 Robot robot NN cord-015369-72cjogxz 2546 2 assisted assist VBD cord-015369-72cjogxz 2546 3 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2546 4 surgery surgery NN cord-015369-72cjogxz 2546 5 is be VBZ cord-015369-72cjogxz 2546 6 an an DT cord-015369-72cjogxz 2546 7 increasing increase VBG cord-015369-72cjogxz 2546 8 field field NN cord-015369-72cjogxz 2546 9 . . . cord-015369-72cjogxz 2547 1 Laparoscopic laparoscopic JJ cord-015369-72cjogxz 2547 2 microsurgery microsurgery NN cord-015369-72cjogxz 2547 3 , , , cord-015369-72cjogxz 2547 4 difficult difficult JJ cord-015369-72cjogxz 2547 5 maneuvers maneuver NNS cord-015369-72cjogxz 2547 6 like like IN cord-015369-72cjogxz 2547 7 intracorporeal intracorporeal NN cord-015369-72cjogxz 2547 8 hand hand NN cord-015369-72cjogxz 2547 9 sewn sew VBN cord-015369-72cjogxz 2547 10 anastomoses anastomosis NNS cord-015369-72cjogxz 2547 11 or or CC cord-015369-72cjogxz 2547 12 a a DT cord-015369-72cjogxz 2547 13 narrow narrow JJ cord-015369-72cjogxz 2547 14 operating operating NN cord-015369-72cjogxz 2547 15 field field NN cord-015369-72cjogxz 2547 16 are be VBP cord-015369-72cjogxz 2547 17 ideal ideal JJ cord-015369-72cjogxz 2547 18 indications indication NNS cord-015369-72cjogxz 2547 19 for for IN cord-015369-72cjogxz 2547 20 the the DT cord-015369-72cjogxz 2547 21 operation operation NN cord-015369-72cjogxz 2547 22 robot robot NN cord-015369-72cjogxz 2547 23 . . . cord-015369-72cjogxz 2548 1 Methods method NNS cord-015369-72cjogxz 2548 2 . . . cord-015369-72cjogxz 2549 1 Tertiary tertiary JJ cord-015369-72cjogxz 2549 2 referral referral NN cord-015369-72cjogxz 2549 3 center center NN cord-015369-72cjogxz 2549 4 with with IN cord-015369-72cjogxz 2549 5 large large JJ cord-015369-72cjogxz 2549 6 expertise expertise NN cord-015369-72cjogxz 2549 7 in in IN cord-015369-72cjogxz 2549 8 robotic robotic JJ cord-015369-72cjogxz 2549 9 surgery surgery NN cord-015369-72cjogxz 2549 10 . . . cord-015369-72cjogxz 2550 1 Five five CD cord-015369-72cjogxz 2550 2 patients patient NNS cord-015369-72cjogxz 2550 3 with with IN cord-015369-72cjogxz 2550 4 Achalasia Achalasia NNP cord-015369-72cjogxz 2550 5 , , , cord-015369-72cjogxz 2550 6 ( ( -LRB- cord-015369-72cjogxz 2550 7 4 4 CD cord-015369-72cjogxz 2550 8 m/1 m/1 NNP cord-015369-72cjogxz 2550 9 f f NNP cord-015369-72cjogxz 2550 10 ) ) -RRB- cord-015369-72cjogxz 2550 11 , , , cord-015369-72cjogxz 2550 12 mean mean VB cord-015369-72cjogxz 2550 13 age age NN cord-015369-72cjogxz 2550 14 44 44 CD cord-015369-72cjogxz 2550 15 ( ( -LRB- cord-015369-72cjogxz 2550 16 34 34 CD cord-015369-72cjogxz 2550 17 - - SYM cord-015369-72cjogxz 2550 18 50 50 CD cord-015369-72cjogxz 2550 19 ) ) -RRB- cord-015369-72cjogxz 2550 20 , , , cord-015369-72cjogxz 2550 21 underwent undergo VBD cord-015369-72cjogxz 2550 22 a a DT cord-015369-72cjogxz 2550 23 robot robot NN cord-015369-72cjogxz 2550 24 assisted assist VBD cord-015369-72cjogxz 2550 25 laparoscopic laparoscopic NNP cord-015369-72cjogxz 2550 26 cardiomyotomy cardiomyotomy NNP cord-015369-72cjogxz 2550 27 ( ( -LRB- cord-015369-72cjogxz 2550 28 RAC RAC NNP cord-015369-72cjogxz 2550 29 ) ) -RRB- cord-015369-72cjogxz 2550 30 with with IN cord-015369-72cjogxz 2550 31 a a DT cord-015369-72cjogxz 2550 32 partial partial JJ cord-015369-72cjogxz 2550 33 posterior posterior NN cord-015369-72cjogxz 2550 34 ( ( -LRB- cord-015369-72cjogxz 2550 35 Toupet Toupet NNP cord-015369-72cjogxz 2550 36 ) ) -RRB- cord-015369-72cjogxz 2550 37 fundoplication fundoplication NN cord-015369-72cjogxz 2550 38 . . . cord-015369-72cjogxz 2551 1 Detailed detailed JJ cord-015369-72cjogxz 2551 2 description description NN cord-015369-72cjogxz 2551 3 of of IN cord-015369-72cjogxz 2551 4 the the DT cord-015369-72cjogxz 2551 5 operation operation NN cord-015369-72cjogxz 2551 6 technique technique NN cord-015369-72cjogxz 2551 7 and and CC cord-015369-72cjogxz 2551 8 review review NN cord-015369-72cjogxz 2551 9 of of IN cord-015369-72cjogxz 2551 10 the the DT cord-015369-72cjogxz 2551 11 literature literature NN cord-015369-72cjogxz 2551 12 . . . cord-015369-72cjogxz 2552 1 Results result NNS cord-015369-72cjogxz 2552 2 . . . cord-015369-72cjogxz 2553 1 The the DT cord-015369-72cjogxz 2553 2 RAC RAC NNP cord-015369-72cjogxz 2553 3 was be VBD cord-015369-72cjogxz 2553 4 feasible feasible JJ cord-015369-72cjogxz 2553 5 without without IN cord-015369-72cjogxz 2553 6 any any DT cord-015369-72cjogxz 2553 7 particular particular JJ cord-015369-72cjogxz 2553 8 problem problem NN cord-015369-72cjogxz 2553 9 and and CC cord-015369-72cjogxz 2553 10 the the DT cord-015369-72cjogxz 2553 11 postoperative postoperative JJ cord-015369-72cjogxz 2553 12 course course NN cord-015369-72cjogxz 2553 13 of of IN cord-015369-72cjogxz 2553 14 all all DT cord-015369-72cjogxz 2553 15 five five CD cord-015369-72cjogxz 2553 16 patients patient NNS cord-015369-72cjogxz 2553 17 was be VBD cord-015369-72cjogxz 2553 18 uneventful uneventful JJ cord-015369-72cjogxz 2553 19 . . . cord-015369-72cjogxz 2554 1 The the DT cord-015369-72cjogxz 2554 2 mean mean JJ cord-015369-72cjogxz 2554 3 operation operation NN cord-015369-72cjogxz 2554 4 time time NN cord-015369-72cjogxz 2554 5 was be VBD cord-015369-72cjogxz 2554 6 257 257 CD cord-015369-72cjogxz 2554 7 min min NN cord-015369-72cjogxz 2554 8 and and CC cord-015369-72cjogxz 2554 9 47 47 CD cord-015369-72cjogxz 2554 10 min min NN cord-015369-72cjogxz 2554 11 setup setup NN cord-015369-72cjogxz 2554 12 - - HYPH cord-015369-72cjogxz 2554 13 time time NN cord-015369-72cjogxz 2554 14 of of IN cord-015369-72cjogxz 2554 15 the the DT cord-015369-72cjogxz 2554 16 robot robot NN cord-015369-72cjogxz 2554 17 . . . cord-015369-72cjogxz 2555 1 On on IN cord-015369-72cjogxz 2555 2 follow follow NN cord-015369-72cjogxz 2555 3 - - HYPH cord-015369-72cjogxz 2555 4 up up NN cord-015369-72cjogxz 2555 5 six six CD cord-015369-72cjogxz 2555 6 months month NNS cord-015369-72cjogxz 2555 7 postoperatively postoperatively RB cord-015369-72cjogxz 2555 8 , , , cord-015369-72cjogxz 2555 9 all all DT cord-015369-72cjogxz 2555 10 patients patient NNS cord-015369-72cjogxz 2555 11 were be VBD cord-015369-72cjogxz 2555 12 free free JJ cord-015369-72cjogxz 2555 13 of of IN cord-015369-72cjogxz 2555 14 significant significant JJ cord-015369-72cjogxz 2555 15 dysphagia dysphagia NN cord-015369-72cjogxz 2555 16 and and CC cord-015369-72cjogxz 2555 17 free free JJ cord-015369-72cjogxz 2555 18 of of IN cord-015369-72cjogxz 2555 19 reflux reflux NN cord-015369-72cjogxz 2555 20 symptoms symptom NNS cord-015369-72cjogxz 2555 21 and and CC cord-015369-72cjogxz 2555 22 had have VBD cord-015369-72cjogxz 2555 23 a a DT cord-015369-72cjogxz 2555 24 significant significant JJ cord-015369-72cjogxz 2555 25 weight weight NN cord-015369-72cjogxz 2555 26 gain gain NN cord-015369-72cjogxz 2555 27 . . . cord-015369-72cjogxz 2556 1 There there EX cord-015369-72cjogxz 2556 2 are be VBP cord-015369-72cjogxz 2556 3 several several JJ cord-015369-72cjogxz 2556 4 reports report NNS cord-015369-72cjogxz 2556 5 , , , cord-015369-72cjogxz 2556 6 series series NN cord-015369-72cjogxz 2556 7 and and CC cord-015369-72cjogxz 2556 8 trials trial NNS cord-015369-72cjogxz 2556 9 about about IN cord-015369-72cjogxz 2556 10 RAC RAC NNP cord-015369-72cjogxz 2556 11 available available JJ cord-015369-72cjogxz 2556 12 in in IN cord-015369-72cjogxz 2556 13 literature literature NN cord-015369-72cjogxz 2556 14 . . . cord-015369-72cjogxz 2557 1 The the DT cord-015369-72cjogxz 2557 2 general general JJ cord-015369-72cjogxz 2557 3 conclusion conclusion NN cord-015369-72cjogxz 2557 4 is be VBZ cord-015369-72cjogxz 2557 5 that that IN cord-015369-72cjogxz 2557 6 this this DT cord-015369-72cjogxz 2557 7 operation operation NN cord-015369-72cjogxz 2557 8 is be VBZ cord-015369-72cjogxz 2557 9 easy easy JJ cord-015369-72cjogxz 2557 10 to to TO cord-015369-72cjogxz 2557 11 perform perform VB cord-015369-72cjogxz 2557 12 in in IN cord-015369-72cjogxz 2557 13 experienced experienced JJ cord-015369-72cjogxz 2557 14 hands hand NNS cord-015369-72cjogxz 2557 15 with with IN cord-015369-72cjogxz 2557 16 a a DT cord-015369-72cjogxz 2557 17 significantly significantly RB cord-015369-72cjogxz 2557 18 lower low JJR cord-015369-72cjogxz 2557 19 rate rate NN cord-015369-72cjogxz 2557 20 of of IN cord-015369-72cjogxz 2557 21 mucosal mucosal JJ cord-015369-72cjogxz 2557 22 perforations perforation NNS cord-015369-72cjogxz 2557 23 , , , cord-015369-72cjogxz 2557 24 but but CC cord-015369-72cjogxz 2557 25 at at IN cord-015369-72cjogxz 2557 26 higher high JJR cord-015369-72cjogxz 2557 27 overall overall JJ cord-015369-72cjogxz 2557 28 costs cost NNS cord-015369-72cjogxz 2557 29 . . . cord-015369-72cjogxz 2558 1 A a DT cord-015369-72cjogxz 2558 2 longer long JJR cord-015369-72cjogxz 2558 3 operation operation NN cord-015369-72cjogxz 2558 4 time time NN cord-015369-72cjogxz 2558 5 has have VBZ cord-015369-72cjogxz 2558 6 to to TO cord-015369-72cjogxz 2558 7 be be VB cord-015369-72cjogxz 2558 8 taken take VBN cord-015369-72cjogxz 2558 9 into into IN cord-015369-72cjogxz 2558 10 account account NN cord-015369-72cjogxz 2558 11 during during IN cord-015369-72cjogxz 2558 12 the the DT cord-015369-72cjogxz 2558 13 learning learning NN cord-015369-72cjogxz 2558 14 curve curve NN cord-015369-72cjogxz 2558 15 . . . cord-015369-72cjogxz 2559 1 Discussion discussion NN cord-015369-72cjogxz 2559 2 . . . cord-015369-72cjogxz 2560 1 The the DT cord-015369-72cjogxz 2560 2 avoidance avoidance NN cord-015369-72cjogxz 2560 3 of of IN cord-015369-72cjogxz 2560 4 mucosal mucosal JJ cord-015369-72cjogxz 2560 5 lacerations laceration NNS cord-015369-72cjogxz 2560 6 and and CC cord-015369-72cjogxz 2560 7 its -PRON- PRP$ cord-015369-72cjogxz 2560 8 possible possible JJ cord-015369-72cjogxz 2560 9 consequences consequence NNS cord-015369-72cjogxz 2560 10 has have VBZ cord-015369-72cjogxz 2560 11 to to TO cord-015369-72cjogxz 2560 12 be be VB cord-015369-72cjogxz 2560 13 weighted weight VBN cord-015369-72cjogxz 2560 14 against against IN cord-015369-72cjogxz 2560 15 higher high JJR cord-015369-72cjogxz 2560 16 overall overall JJ cord-015369-72cjogxz 2560 17 costs cost NNS cord-015369-72cjogxz 2560 18 . . . cord-015369-72cjogxz 2561 1 Conclusions conclusion NNS cord-015369-72cjogxz 2561 2 . . . cord-015369-72cjogxz 2562 1 The the DT cord-015369-72cjogxz 2562 2 RAC RAC NNP cord-015369-72cjogxz 2562 3 is be VBZ cord-015369-72cjogxz 2562 4 the the DT cord-015369-72cjogxz 2562 5 first first JJ cord-015369-72cjogxz 2562 6 ' ' '' cord-015369-72cjogxz 2562 7 ' ' '' cord-015369-72cjogxz 2562 8 standard standard JJ cord-015369-72cjogxz 2562 9 laparoscopic laparoscopic NNP cord-015369-72cjogxz 2562 10 ' ' '' cord-015369-72cjogxz 2562 11 ' ' '' cord-015369-72cjogxz 2562 12 operation operation NN cord-015369-72cjogxz 2562 13 where where WRB cord-015369-72cjogxz 2562 14 a a DT cord-015369-72cjogxz 2562 15 clear clear JJ cord-015369-72cjogxz 2562 16 advantage advantage NN cord-015369-72cjogxz 2562 17 for for IN cord-015369-72cjogxz 2562 18 the the DT cord-015369-72cjogxz 2562 19 application application NN cord-015369-72cjogxz 2562 20 of of IN cord-015369-72cjogxz 2562 21 an an DT cord-015369-72cjogxz 2562 22 operation operation NN cord-015369-72cjogxz 2562 23 robot robot NN cord-015369-72cjogxz 2562 24 has have VBZ cord-015369-72cjogxz 2562 25 been be VBN cord-015369-72cjogxz 2562 26 proven prove VBN cord-015369-72cjogxz 2562 27 . . . cord-015369-72cjogxz 2563 1 Where where WRB cord-015369-72cjogxz 2563 2 available available JJ cord-015369-72cjogxz 2563 3 , , , cord-015369-72cjogxz 2563 4 the the DT cord-015369-72cjogxz 2563 5 operation operation NN cord-015369-72cjogxz 2563 6 robot robot NN cord-015369-72cjogxz 2563 7 should should MD cord-015369-72cjogxz 2563 8 be be VB cord-015369-72cjogxz 2563 9 used use VBN cord-015369-72cjogxz 2563 10 for for IN cord-015369-72cjogxz 2563 11 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2563 12 cardiomyotomies cardiomyotomie NNS cord-015369-72cjogxz 2563 13 . . . cord-015369-72cjogxz 2564 1 Methodik Methodik NNP cord-015369-72cjogxz 2564 2 . . . cord-015369-72cjogxz 2565 1 Bei Bei NNP cord-015369-72cjogxz 2565 2 1515 1515 CD cord-015369-72cjogxz 2566 1 Schockraumadmissionen Schockraumadmissionen NNP cord-015369-72cjogxz 2567 1 i -PRON- PRP cord-015369-72cjogxz 2567 2 m be VBP cord-015369-72cjogxz 2567 3 Beobachtungszeitraum Beobachtungszeitraum NNP cord-015369-72cjogxz 2567 4 mit mit NNP cord-015369-72cjogxz 2567 5 882 882 CD cord-015369-72cjogxz 2567 6 Polytraumata Polytraumata NNP cord-015369-72cjogxz 2567 7 finden finden NNP cord-015369-72cjogxz 2567 8 sich sich NNP cord-015369-72cjogxz 2568 1 265 265 CD cord-015369-72cjogxz 2568 2 stumpfe stumpfe NN cord-015369-72cjogxz 2568 3 und und IN cord-015369-72cjogxz 2568 4 penetrierende penetrierende NNP cord-015369-72cjogxz 2568 5 Verletzungen Verletzungen NNP cord-015369-72cjogxz 2568 6 des des NNP cord-015369-72cjogxz 2568 7 Abdomens abdomen NNS cord-015369-72cjogxz 2568 8 und/ und/ ADD cord-015369-72cjogxz 2569 1 oder oder NNP cord-015369-72cjogxz 2569 2 des des NNP cord-015369-72cjogxz 2569 3 Thorax Thorax NNP cord-015369-72cjogxz 2569 4 . . . cord-015369-72cjogxz 2570 1 Nach Nach NNP cord-015369-72cjogxz 2570 2 klinischer klinischer NNP cord-015369-72cjogxz 2570 3 Diagnostik Diagnostik NNP cord-015369-72cjogxz 2570 4 mit mit NNP cord-015369-72cjogxz 2570 5 obligater obligater JJ cord-015369-72cjogxz 2570 6 Sonographie Sonographie NNP cord-015369-72cjogxz 2571 1 und und RB cord-015369-72cjogxz 2571 2 -bei -bei ADD cord-015369-72cjogxz 2572 1 hämodynamischer hämodynamischer NNP cord-015369-72cjogxz 2572 2 Stabilität Stabilität NNP cord-015369-72cjogxz 2572 3 , , , cord-015369-72cjogxz 2573 1 sowie sowie NNP cord-015369-72cjogxz 2573 2 fehlendem fehlendem NNP cord-015369-72cjogxz 2573 3 Peritonismus Peritonismus NNP cord-015369-72cjogxz 2573 4 oder oder NNP cord-015369-72cjogxz 2574 1 Eviszeration Eviszeration NNP cord-015369-72cjogxz 2574 2 -CT- -CT- . cord-015369-72cjogxz 2575 1 Traumaspirale Traumaspirale NNP cord-015369-72cjogxz 2575 2 lässt lässt NNP cord-015369-72cjogxz 2575 3 sich sich NNP cord-015369-72cjogxz 2575 4 das das NNP cord-015369-72cjogxz 2575 5 Procedere Procedere NNP cord-015369-72cjogxz 2575 6 festlegen festlegen NNP cord-015369-72cjogxz 2575 7 : : : cord-015369-72cjogxz 2576 1 Observanz Observanz NNP cord-015369-72cjogxz 2576 2 und und NNP cord-015369-72cjogxz 2577 1 konservative konservative NNP cord-015369-72cjogxz 2577 2 Therapie Therapie NNP cord-015369-72cjogxz 2577 3 ( ( -LRB- cord-015369-72cjogxz 2577 4 n n NN cord-015369-72cjogxz 2577 5 ¼ ¼ NNP cord-015369-72cjogxz 2577 6 170 170 CD cord-015369-72cjogxz 2577 7 ) ) -RRB- cord-015369-72cjogxz 2577 8 , , . cord-015369-72cjogxz 2578 1 Laparo-/ Laparo-/ . cord-015369-72cjogxz 2579 1 Thorakotomie Thorakotomie NNP cord-015369-72cjogxz 2579 2 ( ( -LRB- cord-015369-72cjogxz 2579 3 n n CC cord-015369-72cjogxz 2579 4 ¼ ¼ NNP cord-015369-72cjogxz 2579 5 89 89 CD cord-015369-72cjogxz 2579 6 ) ) -RRB- cord-015369-72cjogxz 2579 7 oder oder NNP cord-015369-72cjogxz 2579 8 Laparo-/Thorakoskopie Laparo-/Thorakoskopie NNP cord-015369-72cjogxz 2579 9 ( ( -LRB- cord-015369-72cjogxz 2579 10 n n NN cord-015369-72cjogxz 2579 11 ¼ ¼ NNP cord-015369-72cjogxz 2579 12 6 6 CD cord-015369-72cjogxz 2579 13 ) ) -RRB- cord-015369-72cjogxz 2579 14 . . . cord-015369-72cjogxz 2580 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2580 2 . . . cord-015369-72cjogxz 2581 1 Schussverletzungen Schussverletzungen NNP cord-015369-72cjogxz 2581 2 wurden wurden NNP cord-015369-72cjogxz 2581 3 regelhaft regelhaft NNP cord-015369-72cjogxz 2581 4 offen offen NNP cord-015369-72cjogxz 2581 5 versorgt versorgt NNP cord-015369-72cjogxz 2581 6 . . . cord-015369-72cjogxz 2582 1 Alle Alle NNP cord-015369-72cjogxz 2582 2 diaphragmalen diaphragmalen NNP cord-015369-72cjogxz 2583 1 Läsionen Läsionen NNP cord-015369-72cjogxz 2583 2 wurden wurden NNP cord-015369-72cjogxz 2584 1 i -PRON- PRP cord-015369-72cjogxz 2584 2 m be VBP cord-015369-72cjogxz 2584 3 CT CT NNP cord-015369-72cjogxz 2584 4 oder oder NNP cord-015369-72cjogxz 2584 5 per per IN cord-015369-72cjogxz 2584 6 laparotomiam laparotomiam NNP cord-015369-72cjogxz 2584 7 erkannt erkannt NNP cord-015369-72cjogxz 2584 8 und und NNP cord-015369-72cjogxz 2584 9 therapiert therapiert NNP cord-015369-72cjogxz 2584 10 . . . cord-015369-72cjogxz 2585 1 In in IN cord-015369-72cjogxz 2585 2 lediglich lediglich NNP cord-015369-72cjogxz 2585 3 6 6 CD cord-015369-72cjogxz 2585 4 Fällen Fällen NNP cord-015369-72cjogxz 2585 5 kam kam NNP cord-015369-72cjogxz 2585 6 eine eine NNP cord-015369-72cjogxz 2585 7 laparoskopische laparoskopische NNP cord-015369-72cjogxz 2585 8 bzw bzw NNP cord-015369-72cjogxz 2585 9 . . . cord-015369-72cjogxz 2586 1 thorakoskopische thorakoskopische NNP cord-015369-72cjogxz 2586 2 Versorgung Versorgung NNP cord-015369-72cjogxz 2586 3 sicher sicher NNP cord-015369-72cjogxz 2586 4 und und NNP cord-015369-72cjogxz 2587 1 sinnvoll sinnvoll NNP cord-015369-72cjogxz 2587 2 -selbst -selbst NNP cord-015369-72cjogxz 2587 3 bei bei NNP cord-015369-72cjogxz 2587 4 Mehrfachverletzungen Mehrfachverletzungen NNP cord-015369-72cjogxz 2587 5 -zur -zur HYPH cord-015369-72cjogxz 2587 6 Anwendung Anwendung NNP cord-015369-72cjogxz 2587 7 : : : cord-015369-72cjogxz 2588 1 Es Es NNP cord-015369-72cjogxz 2588 2 handelte handelte NNP cord-015369-72cjogxz 2588 3 sich sich NNP cord-015369-72cjogxz 2588 4 um um UH cord-015369-72cjogxz 2588 5 3 3 CD cord-015369-72cjogxz 2588 6 atypische atypische NN cord-015369-72cjogxz 2588 7 pulmonale pulmonale NN cord-015369-72cjogxz 2588 8 Segmentresektionen Segmentresektionen NNP cord-015369-72cjogxz 2588 9 bei bei NNP cord-015369-72cjogxz 2588 10 Stichverletzungen Stichverletzungen NNP cord-015369-72cjogxz 2588 11 , , , cord-015369-72cjogxz 2588 12 je je NNP cord-015369-72cjogxz 2588 13 eine eine NNP cord-015369-72cjogxz 2588 14 Milzklebung Milzklebung NNP cord-015369-72cjogxz 2588 15 , , , cord-015369-72cjogxz 2588 16 eine eine NNP cord-015369-72cjogxz 2588 17 Colonübernähung Colonübernähung NNP cord-015369-72cjogxz 2588 18 , , , cord-015369-72cjogxz 2588 19 einen einen NNP cord-015369-72cjogxz 2588 20 Umstieg Umstieg NNP cord-015369-72cjogxz 2588 21 auf auf NNP cord-015369-72cjogxz 2588 22 offene offene JJ cord-015369-72cjogxz 2588 23 milzerhaltende milzerhaltende NNP cord-015369-72cjogxz 2588 24 Prozedur Prozedur NNP cord-015369-72cjogxz 2588 25 , , , cord-015369-72cjogxz 2588 26 eine eine NNP cord-015369-72cjogxz 2588 27 Perikardfensterung Perikardfensterung NNP cord-015369-72cjogxz 2589 1 und und NNP cord-015369-72cjogxz 2589 2 eine eine NNP cord-015369-72cjogxz 2589 3 rein rein NNP cord-015369-72cjogxz 2590 1 diagnostische diagnostische NNP cord-015369-72cjogxz 2590 2 Laparoskopie Laparoskopie NNP cord-015369-72cjogxz 2590 3 , , , cord-015369-72cjogxz 2590 4 wobei wobei NNP cord-015369-72cjogxz 2590 5 keine keine NNP cord-015369-72cjogxz 2590 6 verfahrensabhängigen verfahrensabhängigen NNP cord-015369-72cjogxz 2590 7 Komplikationen Komplikationen NNP cord-015369-72cjogxz 2590 8 beobachtet beobachtet NNP cord-015369-72cjogxz 2590 9 werden werden NNP cord-015369-72cjogxz 2590 10 mussten mussten NNP cord-015369-72cjogxz 2590 11 . . . cord-015369-72cjogxz 2591 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 2591 2 . . . cord-015369-72cjogxz 2592 1 Penetrierende Penetrierende NNP cord-015369-72cjogxz 2592 2 Verletzungen Verletzungen NNP cord-015369-72cjogxz 2592 3 der der NNP cord-015369-72cjogxz 2592 4 Brustund/ Brustund/ NNP cord-015369-72cjogxz 2593 1 oder oder NNP cord-015369-72cjogxz 2593 2 Leibeshöhle Leibeshöhle NNP cord-015369-72cjogxz 2593 3 stellen stellen NNP cord-015369-72cjogxz 2594 1 für für NNS cord-015369-72cjogxz 2594 2 die die VBP cord-015369-72cjogxz 2594 3 Chirurgische Chirurgische NNP cord-015369-72cjogxz 2594 4 Versorgung Versorgung NNP cord-015369-72cjogxz 2595 1 eine eine NNP cord-015369-72cjogxz 2595 2 Herausforderung Herausforderung NNP cord-015369-72cjogxz 2595 3 dar dar NNP cord-015369-72cjogxz 2595 4 : : : cord-015369-72cjogxz 2596 1 Einerseits Einerseits NNP cord-015369-72cjogxz 2596 2 darf darf NNP cord-015369-72cjogxz 2596 3 der der NNP cord-015369-72cjogxz 2596 4 Diagnostik Diagnostik NNP cord-015369-72cjogxz 2596 5 keine keine NNP cord-015369-72cjogxz 2596 6 Läsion Läsion NNP cord-015369-72cjogxz 2596 7 entgehen entgehen NNP cord-015369-72cjogxz 2596 8 , , , cord-015369-72cjogxz 2596 9 andererseits andererseit NNS cord-015369-72cjogxz 2596 10 muß muß NNP cord-015369-72cjogxz 2596 11 eine eine NNP cord-015369-72cjogxz 2596 12 Ü Ü NNP cord-015369-72cjogxz 2596 13 berversorgung berversorgung NNP cord-015369-72cjogxz 2596 14 mit mit NNP cord-015369-72cjogxz 2596 15 dem dem NNP cord-015369-72cjogxz 2596 16 Eigenrisiko Eigenrisiko NNP cord-015369-72cjogxz 2596 17 einer einer NNP cord-015369-72cjogxz 2596 18 negativen negativen NNP cord-015369-72cjogxz 2596 19 Explorationslaparotomie Explorationslaparotomie NNP cord-015369-72cjogxz 2596 20 vermieden vermieden NNP cord-015369-72cjogxz 2596 21 werden werden NNP cord-015369-72cjogxz 2596 22 . . . cord-015369-72cjogxz 2597 1 Klinische Klinische NNP cord-015369-72cjogxz 2597 2 , , , cord-015369-72cjogxz 2597 3 sonographische sonographische NNP cord-015369-72cjogxz 2597 4 und und IN cord-015369-72cjogxz 2597 5 computertomographischeggf computertomographischeggf NNP cord-015369-72cjogxz 2597 6 . . . cord-015369-72cjogxz 2598 1 wiederholte wiederholte NNP cord-015369-72cjogxz 2598 2 Untersuchungen Untersuchungen NNP cord-015369-72cjogxz 2598 3 -lassen -lassen CD cord-015369-72cjogxz 2598 4 nur nur NNP cord-015369-72cjogxz 2598 5 in in IN cord-015369-72cjogxz 2598 6 hochselektiven hochselektiven NNP cord-015369-72cjogxz 2598 7 Situationen Situationen NNP cord-015369-72cjogxz 2598 8 eine eine NNP cord-015369-72cjogxz 2598 9 endoskopische endoskopische NNP cord-015369-72cjogxz 2598 10 Annäherung Annäherung NNP cord-015369-72cjogxz 2598 11 sinnvoll sinnvoll NNP cord-015369-72cjogxz 2598 12 erscheinen erscheinen NNP cord-015369-72cjogxz 2598 13 , , , cord-015369-72cjogxz 2598 14 zumal zumal NNP cord-015369-72cjogxz 2598 15 den den NNP cord-015369-72cjogxz 2599 1 therapeutischen therapeutischen NNP cord-015369-72cjogxz 2599 2 endoskopischen endoskopischen NNP cord-015369-72cjogxz 2600 1 Verfahren Verfahren NNP cord-015369-72cjogxz 2600 2 technische technische NNP cord-015369-72cjogxz 2601 1 Grenzen Grenzen NNP cord-015369-72cjogxz 2601 2 gesetzt gesetzt NN cord-015369-72cjogxz 2601 3 sind sind NNP cord-015369-72cjogxz 2601 4 . . . cord-015369-72cjogxz 2602 1 Unbestreitbar Unbestreitbar NNP cord-015369-72cjogxz 2602 2 ist ist NNP cord-015369-72cjogxz 2603 1 allerdings allerdings NNP cord-015369-72cjogxz 2603 2 ihr ihr NNP cord-015369-72cjogxz 2603 3 Wert Wert NNP cord-015369-72cjogxz 2604 1 bezüglich bezüglich NNP cord-015369-72cjogxz 2604 2 einer einer NNP cord-015369-72cjogxz 2604 3 harten harten NNP cord-015369-72cjogxz 2604 4 forensischen forensischen NNP cord-015369-72cjogxz 2604 5 Dokumentation Dokumentation NNP cord-015369-72cjogxz 2604 6 . . . cord-015369-72cjogxz 2605 1 BMI BMI NNP cord-015369-72cjogxz 2605 2 26 26 CD cord-015369-72cjogxz 2605 3 , , , cord-015369-72cjogxz 2605 4 9 9 CD cord-015369-72cjogxz 2605 5 ( ( -LRB- cord-015369-72cjogxz 2605 6 16 16 CD cord-015369-72cjogxz 2605 7 , , , cord-015369-72cjogxz 2605 8 1 1 CD cord-015369-72cjogxz 2605 9 ) ) -RRB- cord-015369-72cjogxz 2606 1 kg/ kg/ NNP cord-015369-72cjogxz 2607 1 m m LS cord-015369-72cjogxz 2607 2 2 2 CD cord-015369-72cjogxz 2607 3 ) ) -RRB- cord-015369-72cjogxz 2607 4 mit mit NNP cord-015369-72cjogxz 2607 5 einer einer NNP cord-015369-72cjogxz 2607 6 ITP ITP NNP cord-015369-72cjogxz 2607 7 laparoskopisch laparoskopisch NNP cord-015369-72cjogxz 2607 8 splenektomiert splenektomiert NNP cord-015369-72cjogxz 2607 9 . . . cord-015369-72cjogxz 2608 1 In in IN cord-015369-72cjogxz 2608 2 einer einer FW cord-015369-72cjogxz 2608 3 univariaten univariaten NNP cord-015369-72cjogxz 2608 4 Analyse analyse NN cord-015369-72cjogxz 2608 5 wurde wurde NNP cord-015369-72cjogxz 2608 6 der der NNP cord-015369-72cjogxz 2608 7 Einfluss Einfluss NNP cord-015369-72cjogxz 2608 8 von von NNP cord-015369-72cjogxz 2608 9 Alter Alter NNP cord-015369-72cjogxz 2608 10 , , , cord-015369-72cjogxz 2608 11 BMI BMI NNP cord-015369-72cjogxz 2608 12 , , , cord-015369-72cjogxz 2608 13 ASA ASA NNP cord-015369-72cjogxz 2608 14 - - HYPH cord-015369-72cjogxz 2608 15 Score Score NNP cord-015369-72cjogxz 2608 16 , , , cord-015369-72cjogxz 2608 17 Krankheitsdauer Krankheitsdauer NNP cord-015369-72cjogxz 2608 18 , , , cord-015369-72cjogxz 2608 19 medikamentöser medikamentöser NNP cord-015369-72cjogxz 2608 20 Therapie Therapie NNP cord-015369-72cjogxz 2608 21 , , , cord-015369-72cjogxz 2608 22 OP OP NNP cord-015369-72cjogxz 2608 23 - - HYPH cord-015369-72cjogxz 2608 24 Dauer Dauer NNP cord-015369-72cjogxz 2608 25 , , , cord-015369-72cjogxz 2608 26 Konversion Konversion NNP cord-015369-72cjogxz 2608 27 , , , cord-015369-72cjogxz 2608 28 Komplikation Komplikation NNP cord-015369-72cjogxz 2608 29 , , , cord-015369-72cjogxz 2608 30 Milzgewicht Milzgewicht NNP cord-015369-72cjogxz 2608 31 , , , cord-015369-72cjogxz 2608 32 präoperativen präoperativen NNP cord-015369-72cjogxz 2608 33 Thrombozytenzahlen Thrombozytenzahlen NNP cord-015369-72cjogxz 2608 34 , , , cord-015369-72cjogxz 2608 35 Thrombozytenanstieg Thrombozytenanstieg NNP cord-015369-72cjogxz 2608 36 und und IN cord-015369-72cjogxz 2608 37 Blutproduktsubstitution Blutproduktsubstitution NNP cord-015369-72cjogxz 2608 38 auf auf NNP cord-015369-72cjogxz 2608 39 das das NNP cord-015369-72cjogxz 2608 40 Langzeitergebnis Langzeitergebnis NNP cord-015369-72cjogxz 2608 41 ausgewertet ausgewertet NNP cord-015369-72cjogxz 2609 1 ( ( -LRB- cord-015369-72cjogxz 2609 2 ANOVA ANOVA NNP cord-015369-72cjogxz 2609 3 mit mit NNP cord-015369-72cjogxz 2609 4 Bonferroni Bonferroni NNP cord-015369-72cjogxz 2609 5 post post VBP cord-015369-72cjogxz 2609 6 hoc hoc JJ cord-015369-72cjogxz 2609 7 Test test NN cord-015369-72cjogxz 2609 8 , , , cord-015369-72cjogxz 2609 9 Kruskal Kruskal NNP cord-015369-72cjogxz 2609 10 - - HYPH cord-015369-72cjogxz 2609 11 Wallis Wallis NNP cord-015369-72cjogxz 2609 12 - - HYPH cord-015369-72cjogxz 2609 13 Test Test NNP cord-015369-72cjogxz 2609 14 ) ) -RRB- cord-015369-72cjogxz 2609 15 . . . cord-015369-72cjogxz 2610 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2610 2 . . . cord-015369-72cjogxz 2611 1 Die die VB cord-015369-72cjogxz 2611 2 Erkrankungsdauer Erkrankungsdauer NNP cord-015369-72cjogxz 2611 3 lag lag VB cord-015369-72cjogxz 2611 4 bei bei NNP cord-015369-72cjogxz 2611 5 1,5 1,5 CD cord-015369-72cjogxz 2611 6 ( ( -LRB- cord-015369-72cjogxz 2611 7 0,25 0,25 CD cord-015369-72cjogxz 2611 8 - - HYPH cord-015369-72cjogxz 2611 9 25 25 CD cord-015369-72cjogxz 2611 10 ) ) -RRB- cord-015369-72cjogxz 2611 11 Jahren Jahren NNP cord-015369-72cjogxz 2611 12 . . . cord-015369-72cjogxz 2612 1 Das Das NNP cord-015369-72cjogxz 2612 2 Milzgewicht Milzgewicht NNP cord-015369-72cjogxz 2612 3 betrug betrug NNP cord-015369-72cjogxz 2612 4 150 150 CD cord-015369-72cjogxz 2612 5 ( ( -LRB- cord-015369-72cjogxz 2612 6 70 70 CD cord-015369-72cjogxz 2612 7 - - SYM cord-015369-72cjogxz 2612 8 350 350 CD cord-015369-72cjogxz 2612 9 ) ) -RRB- cord-015369-72cjogxz 2612 10 g. g. NNP cord-015369-72cjogxz 2612 11 Die Die NNP cord-015369-72cjogxz 2612 12 Operationsdauer Operationsdauer NNP cord-015369-72cjogxz 2612 13 betrug betrug NNP cord-015369-72cjogxz 2612 14 123 123 CD cord-015369-72cjogxz 2612 15 ( ( -LRB- cord-015369-72cjogxz 2612 16 28 28 CD cord-015369-72cjogxz 2612 17 - - SYM cord-015369-72cjogxz 2612 18 297 297 CD cord-015369-72cjogxz 2612 19 ) ) -RRB- cord-015369-72cjogxz 2613 1 Minuten Minuten NNP cord-015369-72cjogxz 2613 2 . . . cord-015369-72cjogxz 2614 1 Konversionen Konversionen NNP cord-015369-72cjogxz 2614 2 erfolgten erfolgten NNP cord-015369-72cjogxz 2614 3 in in IN cord-015369-72cjogxz 2614 4 8 8 CD cord-015369-72cjogxz 2614 5 % % NN cord-015369-72cjogxz 2614 6 . . . cord-015369-72cjogxz 2615 1 Die die VB cord-015369-72cjogxz 2615 2 Thrombozytenzahl Thrombozytenzahl NNP cord-015369-72cjogxz 2615 3 stieg stieg NNP cord-015369-72cjogxz 2615 4 um um UH cord-015369-72cjogxz 2615 5 793 793 CD cord-015369-72cjogxz 2615 6 % % NN cord-015369-72cjogxz 2615 7 ( ( -LRB- cord-015369-72cjogxz 2615 8 präoperativ präoperativ NNP cord-015369-72cjogxz 2615 9 67 67 CD cord-015369-72cjogxz 2615 10 ( ( -LRB- cord-015369-72cjogxz 2615 11 3 3 CD cord-015369-72cjogxz 2615 12 - - SYM cord-015369-72cjogxz 2615 13 318 318 CD cord-015369-72cjogxz 2615 14 ) ) -RRB- cord-015369-72cjogxz 2616 1 Tsd Tsd NNP cord-015369-72cjogxz 2616 2 / / SYM cord-015369-72cjogxz 2616 3 ml ml XX cord-015369-72cjogxz 2616 4 , , , cord-015369-72cjogxz 2616 5 bei bei NNP cord-015369-72cjogxz 2616 6 Entlassung Entlassung NNP cord-015369-72cjogxz 2616 7 247 247 CD cord-015369-72cjogxz 2617 1 ( ( -LRB- cord-015369-72cjogxz 2617 2 31 31 CD cord-015369-72cjogxz 2617 3 - - SYM cord-015369-72cjogxz 2617 4 835 835 CD cord-015369-72cjogxz 2617 5 ) ) -RRB- cord-015369-72cjogxz 2617 6 Tsd Tsd NNP cord-015369-72cjogxz 2617 7 / / SYM cord-015369-72cjogxz 2617 8 ml ml NN cord-015369-72cjogxz 2617 9 ) ) -RRB- cord-015369-72cjogxz 2617 10 . . . cord-015369-72cjogxz 2618 1 Die die VB cord-015369-72cjogxz 2618 2 Morbidität Morbidität NNP cord-015369-72cjogxz 2618 3 war war NN cord-015369-72cjogxz 2618 4 11,4 11,4 CD cord-015369-72cjogxz 2618 5 % % NN cord-015369-72cjogxz 2618 6 , , , cord-015369-72cjogxz 2618 7 die die VBP cord-015369-72cjogxz 2618 8 Letalität Letalität NNP cord-015369-72cjogxz 2618 9 0 0 CD cord-015369-72cjogxz 2618 10 % % NN cord-015369-72cjogxz 2618 11 . . . cord-015369-72cjogxz 2619 1 Die die VB cord-015369-72cjogxz 2619 2 Liegezeit Liegezeit NNP cord-015369-72cjogxz 2619 3 betrug betrug NNP cord-015369-72cjogxz 2619 4 6 6 CD cord-015369-72cjogxz 2620 1 ( ( -LRB- cord-015369-72cjogxz 2620 2 3 3 CD cord-015369-72cjogxz 2620 3 - - SYM cord-015369-72cjogxz 2620 4 17 17 CD cord-015369-72cjogxz 2620 5 ) ) -RRB- cord-015369-72cjogxz 2620 6 Tage Tage NNP cord-015369-72cjogxz 2620 7 . . . cord-015369-72cjogxz 2621 1 Das Das NNP cord-015369-72cjogxz 2621 2 mediane mediane NNP cord-015369-72cjogxz 2622 1 Follow follow VB cord-015369-72cjogxz 2622 2 - - HYPH cord-015369-72cjogxz 2622 3 up up RP cord-015369-72cjogxz 2622 4 betrug betrug NNP cord-015369-72cjogxz 2622 5 12 12 CD cord-015369-72cjogxz 2622 6 Monate Monate NNP cord-015369-72cjogxz 2622 7 ( ( -LRB- cord-015369-72cjogxz 2622 8 0,25 0,25 CD cord-015369-72cjogxz 2622 9 - - HYPH cord-015369-72cjogxz 2622 10 5,7 5,7 CD cord-015369-72cjogxz 2622 11 Jahre Jahre NNP cord-015369-72cjogxz 2622 12 ) ) -RRB- cord-015369-72cjogxz 2622 13 . . . cord-015369-72cjogxz 2623 1 Dauerhaft Dauerhaft NNP cord-015369-72cjogxz 2623 2 normwertige normwertige NNP cord-015369-72cjogxz 2624 1 Thrombozytenzahlen Thrombozytenzahlen NNP cord-015369-72cjogxz 2624 2 konnten konnten NNP cord-015369-72cjogxz 2624 3 bei bei NNP cord-015369-72cjogxz 2624 4 70,5 70,5 CD cord-015369-72cjogxz 2624 5 % % NN cord-015369-72cjogxz 2624 6 der der NNP cord-015369-72cjogxz 2624 7 Patienten Patienten NNP cord-015369-72cjogxz 2624 8 erzielt erzielt NNS cord-015369-72cjogxz 2624 9 werden werden NNP cord-015369-72cjogxz 2624 10 . . . cord-015369-72cjogxz 2625 1 4 4 LS cord-015369-72cjogxz 2626 1 Patienten Patienten NNP cord-015369-72cjogxz 2626 2 zeigten zeigten NNS cord-015369-72cjogxz 2626 3 keinen keinen NN cord-015369-72cjogxz 2626 4 Thrombozytenanstieg Thrombozytenanstieg NNP cord-015369-72cjogxz 2626 5 nach nach NNP cord-015369-72cjogxz 2626 6 Splenektomie Splenektomie NNP cord-015369-72cjogxz 2626 7 , , , cord-015369-72cjogxz 2626 8 während während NNP cord-015369-72cjogxz 2626 9 13 13 CD cord-015369-72cjogxz 2626 10 Patienten Patienten NNP cord-015369-72cjogxz 2626 11 nach nach NNP cord-015369-72cjogxz 2626 12 5 5 CD cord-015369-72cjogxz 2626 13 ( ( -LRB- cord-015369-72cjogxz 2626 14 1 1 CD cord-015369-72cjogxz 2626 15 - - SYM cord-015369-72cjogxz 2626 16 68 68 CD cord-015369-72cjogxz 2626 17 ) ) -RRB- cord-015369-72cjogxz 2627 1 Monaten Monaten NNP cord-015369-72cjogxz 2627 2 eine eine NNP cord-015369-72cjogxz 2627 3 Rezidiv Rezidiv NNP cord-015369-72cjogxz 2627 4 - - HYPH cord-015369-72cjogxz 2627 5 Thrombopenie Thrombopenie NNP cord-015369-72cjogxz 2627 6 entwickelten entwickelten NN cord-015369-72cjogxz 2627 7 . . . cord-015369-72cjogxz 2628 1 Patienten Patienten NNP cord-015369-72cjogxz 2628 2 mit mit NNP cord-015369-72cjogxz 2628 3 einer einer NNP cord-015369-72cjogxz 2628 4 primären primären NNP cord-015369-72cjogxz 2629 1 postoperativen postoperativen NNP cord-015369-72cjogxz 2630 1 Thrombozytopenie Thrombozytopenie NNP cord-015369-72cjogxz 2631 1 < < NNP cord-015369-72cjogxz 2631 2 60.000 60.000 CD cord-015369-72cjogxz 2631 3 / / SYM cord-015369-72cjogxz 2631 4 ml ml NN cord-015369-72cjogxz 2631 5 waren waren NNP cord-015369-72cjogxz 2631 6 Therapieversager Therapieversager NNP cord-015369-72cjogxz 2631 7 ( ( -LRB- cord-015369-72cjogxz 2631 8 3/3 3/3 CD cord-015369-72cjogxz 2631 9 ) ) -RRB- cord-015369-72cjogxz 2631 10 , , , cord-015369-72cjogxz 2631 11 postoperative postoperative JJ cord-015369-72cjogxz 2631 12 Thrombozytenwerte Thrombozytenwerte NNP cord-015369-72cjogxz 2631 13 zwischen zwischen NNP cord-015369-72cjogxz 2631 14 60.000 60.000 CD cord-015369-72cjogxz 2632 1 /ml /ml . cord-015369-72cjogxz 2632 2 und und RB cord-015369-72cjogxz 2633 1 150.000 150.000 CD cord-015369-72cjogxz 2633 2 / / SYM cord-015369-72cjogxz 2633 3 ml ml NN cord-015369-72cjogxz 2633 4 resultierten resultierten NNP cord-015369-72cjogxz 2633 5 in in IN cord-015369-72cjogxz 2633 6 partieller partieller NN cord-015369-72cjogxz 2633 7 ( ( -LRB- cord-015369-72cjogxz 2633 8 4/11 4/11 CD cord-015369-72cjogxz 2633 9 ) ) -RRB- cord-015369-72cjogxz 2634 1 und und NNP cord-015369-72cjogxz 2635 1 kompletter kompletter NNP cord-015369-72cjogxz 2635 2 ( ( -LRB- cord-015369-72cjogxz 2635 3 7/11 7/11 CD cord-015369-72cjogxz 2635 4 ) ) -RRB- cord-015369-72cjogxz 2635 5 Remission remission NN cord-015369-72cjogxz 2636 1 , , , cord-015369-72cjogxz 2636 2 während während NNP cord-015369-72cjogxz 2636 3 Thrombozyten Thrombozyten NNP cord-015369-72cjogxz 2637 1 > > XX cord-015369-72cjogxz 2638 1 150.000 150.000 CD cord-015369-72cjogxz 2638 2 / / SYM cord-015369-72cjogxz 2638 3 ml ml NN cord-015369-72cjogxz 2639 1 überwiegend überwiegend NNP cord-015369-72cjogxz 2640 1 zu zu NNP cord-015369-72cjogxz 2640 2 einer einer NNP cord-015369-72cjogxz 2640 3 kompletten kompletten NNP cord-015369-72cjogxz 2640 4 Remission Remission NNP cord-015369-72cjogxz 2640 5 ( ( -LRB- cord-015369-72cjogxz 2640 6 35/42 35/42 CD cord-015369-72cjogxz 2640 7 ) ) -RRB- cord-015369-72cjogxz 2640 8 führten führten NNP cord-015369-72cjogxz 2640 9 . . . cord-015369-72cjogxz 2641 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 2641 2 . . . cord-015369-72cjogxz 2642 1 Die die VB cord-015369-72cjogxz 2642 2 laparoskopische laparoskopische NNP cord-015369-72cjogxz 2643 1 Splenektomie splenektomie NN cord-015369-72cjogxz 2643 2 ist ist NNP cord-015369-72cjogxz 2644 1 ein ein NNP cord-015369-72cjogxz 2644 2 sicheres sicheres NNP cord-015369-72cjogxz 2644 3 Verfahren Verfahren NNP cord-015369-72cjogxz 2644 4 bei bei NNP cord-015369-72cjogxz 2644 5 selektionierten selektionierten NNP cord-015369-72cjogxz 2645 1 Patienten Patienten NNP cord-015369-72cjogxz 2645 2 und und XX cord-015369-72cjogxz 2646 1 gilt gilt NNP cord-015369-72cjogxz 2646 2 als als NN cord-015369-72cjogxz 2646 3 chirurgisches chirurgisches NNP cord-015369-72cjogxz 2647 1 Standardverfahren Standardverfahren NNP cord-015369-72cjogxz 2647 2 bei bei NNP cord-015369-72cjogxz 2647 3 der der NNP cord-015369-72cjogxz 2647 4 therapierefraktären therapierefraktären NNP cord-015369-72cjogxz 2647 5 ITP ITP NNP cord-015369-72cjogxz 2647 6 . . . cord-015369-72cjogxz 2648 1 Die die VB cord-015369-72cjogxz 2648 2 Ansprechrate Ansprechrate NNP cord-015369-72cjogxz 2648 3 liegt liegt NNP cord-015369-72cjogxz 2648 4 bei bei NNP cord-015369-72cjogxz 2648 5 70 70 CD cord-015369-72cjogxz 2648 6 % % NN cord-015369-72cjogxz 2648 7 . . . cord-015369-72cjogxz 2649 1 Die die VB cord-015369-72cjogxz 2649 2 postoperativen postoperativen NNP cord-015369-72cjogxz 2650 1 Thrombozytenwerte Thrombozytenwerte NNP cord-015369-72cjogxz 2650 2 sind sind NNP cord-015369-72cjogxz 2651 1 ein ein NNP cord-015369-72cjogxz 2651 2 Prediktor Prediktor NNP cord-015369-72cjogxz 2651 3 für für IN cord-015369-72cjogxz 2651 4 den den NNP cord-015369-72cjogxz 2651 5 Langzeitverlauf Langzeitverlauf NNP cord-015369-72cjogxz 2651 6 , , , cord-015369-72cjogxz 2652 1 während während NNP cord-015369-72cjogxz 2652 2 periopereative periopereative NNP cord-015369-72cjogxz 2652 3 Komplikationen Komplikationen NNP cord-015369-72cjogxz 2652 4 keinen keinen NNP cord-015369-72cjogxz 2653 1 Einfluss Einfluss NNP cord-015369-72cjogxz 2653 2 auf auf NNP cord-015369-72cjogxz 2653 3 die die VBP cord-015369-72cjogxz 2653 4 Rezidivrate Rezidivrate NNP cord-015369-72cjogxz 2653 5 haben haben NNP cord-015369-72cjogxz 2653 6 . . . cord-015369-72cjogxz 2654 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 2654 2 . . . cord-015369-72cjogxz 2655 1 Die die VB cord-015369-72cjogxz 2655 2 Verwendung Verwendung NNP cord-015369-72cjogxz 2655 3 von von NNP cord-015369-72cjogxz 2655 4 sogenannten sogenannten NNP cord-015369-72cjogxz 2655 5 Perforator Perforator NNP cord-015369-72cjogxz 2655 6 - - HYPH cord-015369-72cjogxz 2655 7 Lappen Lappen NNP cord-015369-72cjogxz 2655 8 in in IN cord-015369-72cjogxz 2655 9 der der NNP cord-015369-72cjogxz 2655 10 Plastischen Plastischen NNP cord-015369-72cjogxz 2655 11 Chirurgie Chirurgie NNP cord-015369-72cjogxz 2655 12 konnte konnte NNP cord-015369-72cjogxz 2655 13 in in IN cord-015369-72cjogxz 2655 14 der der NNP cord-015369-72cjogxz 2655 15 rezenten rezenten NNP cord-015369-72cjogxz 2655 16 Vergangenheit Vergangenheit NNP cord-015369-72cjogxz 2655 17 zum zum VBD cord-015369-72cjogxz 2655 18 einen einen NNP cord-015369-72cjogxz 2655 19 zu zu NNP cord-015369-72cjogxz 2655 20 einer einer NNP cord-015369-72cjogxz 2655 21 massiven massiven NNP cord-015369-72cjogxz 2655 22 Reduktion Reduktion NNP cord-015369-72cjogxz 2655 23 der der NNP cord-015369-72cjogxz 2655 24 Hebedefektmorbidität Hebedefektmorbidität NNP cord-015369-72cjogxz 2655 25 und und DT cord-015369-72cjogxz 2655 26 zum zum NNP cord-015369-72cjogxz 2656 1 anderen anderen NNP cord-015369-72cjogxz 2656 2 zu zu NNP cord-015369-72cjogxz 2657 1 einer einer NNP cord-015369-72cjogxz 2657 2 größeren größeren NNP cord-015369-72cjogxz 2658 1 Flexibilität Flexibilität NNS cord-015369-72cjogxz 2658 2 i -PRON- PRP cord-015369-72cjogxz 2658 3 m be VBP cord-015369-72cjogxz 2658 4 Lappendesign Lappendesign NNP cord-015369-72cjogxz 2658 5 beitragen beitragen NNP cord-015369-72cjogxz 2658 6 . . . cord-015369-72cjogxz 2659 1 Vorallem vorallem UH cord-015369-72cjogxz 2659 2 i -PRON- PRP cord-015369-72cjogxz 2659 3 m be VBP cord-015369-72cjogxz 2659 4 Bereich Bereich NNP cord-015369-72cjogxz 2659 5 der der NNP cord-015369-72cjogxz 2659 6 Mammarekonstruktion Mammarekonstruktion NNP cord-015369-72cjogxz 2659 7 ist ist NN cord-015369-72cjogxz 2659 8 der der NNP cord-015369-72cjogxz 2659 9 Deep deep JJ cord-015369-72cjogxz 2659 10 - - HYPH cord-015369-72cjogxz 2659 11 Inferior Inferior NNP cord-015369-72cjogxz 2659 12 - - HYPH cord-015369-72cjogxz 2659 13 Epigastric Epigastric NNP cord-015369-72cjogxz 2659 14 - - HYPH cord-015369-72cjogxz 2659 15 Artery Artery NNP cord-015369-72cjogxz 2659 16 - - HYPH cord-015369-72cjogxz 2659 17 Perforator Perforator NNP cord-015369-72cjogxz 2659 18 - - HYPH cord-015369-72cjogxz 2659 19 Falp Falp NNP cord-015369-72cjogxz 2660 1 ( ( -LRB- cord-015369-72cjogxz 2660 2 DIEAP DIEAP NNP cord-015369-72cjogxz 2660 3 - - HYPH cord-015369-72cjogxz 2660 4 flap flap NN cord-015369-72cjogxz 2660 5 ) ) -RRB- cord-015369-72cjogxz 2660 6 mittlerweile mittlerweile NNP cord-015369-72cjogxz 2660 7 zu zu NNP cord-015369-72cjogxz 2660 8 einem einem NNP cord-015369-72cjogxz 2660 9 operativen operativen NNP cord-015369-72cjogxz 2660 10 Standard Standard NNP cord-015369-72cjogxz 2660 11 geworden geworden NNP cord-015369-72cjogxz 2660 12 . . . cord-015369-72cjogxz 2661 1 In in IN cord-015369-72cjogxz 2661 2 der der NN cord-015369-72cjogxz 2661 3 vorliegenden vorliegenden VBN cord-015369-72cjogxz 2661 4 Untersuchung Untersuchung NNP cord-015369-72cjogxz 2661 5 soll soll NNP cord-015369-72cjogxz 2661 6 die die VB cord-015369-72cjogxz 2661 7 Bedeutung Bedeutung NNP cord-015369-72cjogxz 2661 8 der der NNP cord-015369-72cjogxz 2662 1 präoperativen präoperativen NNP cord-015369-72cjogxz 2662 2 Darstellung Darstellung NNP cord-015369-72cjogxz 2662 3 der der NNP cord-015369-72cjogxz 2662 4 Perforatorgefäße Perforatorgefäße NNP cord-015369-72cjogxz 2662 5 mittels mittel NNS cord-015369-72cjogxz 2663 1 CT CT NNP cord-015369-72cjogxz 2663 2 - - HYPH cord-015369-72cjogxz 2663 3 Angiographie Angiographie NNP cord-015369-72cjogxz 2663 4 untersucht untersucht FW cord-015369-72cjogxz 2663 5 werden werden NNP cord-015369-72cjogxz 2663 6 . . . cord-015369-72cjogxz 2664 1 Methodik Methodik NNP cord-015369-72cjogxz 2664 2 . . . cord-015369-72cjogxz 2665 1 Insgesamt Insgesamt NNP cord-015369-72cjogxz 2665 2 wurden wurden VBD cord-015369-72cjogxz 2665 3 an an DT cord-015369-72cjogxz 2665 4 unserer unserer JJ cord-015369-72cjogxz 2665 5 Abteilung Abteilung NNP cord-015369-72cjogxz 2665 6 bei bei NNP cord-015369-72cjogxz 2665 7 61 61 CD cord-015369-72cjogxz 2666 1 von von NNP cord-015369-72cjogxz 2666 2 345 345 CD cord-015369-72cjogxz 2666 3 Patientinnen Patientinnen NNP cord-015369-72cjogxz 2666 4 seit seit NNP cord-015369-72cjogxz 2666 5 Mai Mai NNP cord-015369-72cjogxz 2666 6 2000 2000 CD cord-015369-72cjogxz 2666 7 Mammarekonstruktionen Mammarekonstruktionen NNP cord-015369-72cjogxz 2666 8 mittels mittels NNP cord-015369-72cjogxz 2666 9 DIEAP DIEAP NNS cord-015369-72cjogxz 2666 10 - - HYPH cord-015369-72cjogxz 2666 11 flaps flap NNS cord-015369-72cjogxz 2666 12 durchgeführt durchgeführt NN cord-015369-72cjogxz 2666 13 . . . cord-015369-72cjogxz 2667 1 Bei Bei NNP cord-015369-72cjogxz 2667 2 15 15 CD cord-015369-72cjogxz 2667 3 von von NNP cord-015369-72cjogxz 2667 4 61 61 CD cord-015369-72cjogxz 2667 5 Patientinnen Patientinnen NNP cord-015369-72cjogxz 2667 6 wurde wurde NN cord-015369-72cjogxz 2667 7 präoperativ präoperativ NNP cord-015369-72cjogxz 2667 8 eine eine NNP cord-015369-72cjogxz 2667 9 CT CT NNP cord-015369-72cjogxz 2667 10 - - HYPH cord-015369-72cjogxz 2667 11 Angiographie Angiographie NNP cord-015369-72cjogxz 2667 12 zur zur NNP cord-015369-72cjogxz 2667 13 Darstellung Darstellung NNP cord-015369-72cjogxz 2667 14 der der NNP cord-015369-72cjogxz 2667 15 Perforatorgefäße Perforatorgefäße NNP cord-015369-72cjogxz 2667 16 vorgenommen vorgenomman NNS cord-015369-72cjogxz 2667 17 . . . cord-015369-72cjogxz 2668 1 Anhand Anhand NNP cord-015369-72cjogxz 2668 2 von von NNP cord-015369-72cjogxz 2668 3 Beispielen Beispielen NNP cord-015369-72cjogxz 2668 4 sollen sollen NNP cord-015369-72cjogxz 2669 1 sowohl sowohl NNP cord-015369-72cjogxz 2669 2 die die VB cord-015369-72cjogxz 2670 1 Praktikabilität Praktikabilität NNP cord-015369-72cjogxz 2670 2 als als NNP cord-015369-72cjogxz 2670 3 auch auch NNP cord-015369-72cjogxz 2670 4 die die VB cord-015369-72cjogxz 2671 1 Vorteile Vorteile NNP cord-015369-72cjogxz 2671 2 der der NNP cord-015369-72cjogxz 2671 3 Untersuchung Untersuchung NNP cord-015369-72cjogxz 2671 4 verdeutlicht verdeutlicht NN cord-015369-72cjogxz 2671 5 werden werden NNP cord-015369-72cjogxz 2671 6 . . . cord-015369-72cjogxz 2672 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2672 2 . . . cord-015369-72cjogxz 2673 1 In in IN cord-015369-72cjogxz 2673 2 keinem keinem NNP cord-015369-72cjogxz 2673 3 der der NNP cord-015369-72cjogxz 2673 4 Fälle Fälle NNP cord-015369-72cjogxz 2673 5 mit mit NNP cord-015369-72cjogxz 2673 6 präoperativer präoperativer NNP cord-015369-72cjogxz 2673 7 CT CT NNP cord-015369-72cjogxz 2673 8 - - HYPH cord-015369-72cjogxz 2673 9 Angiographie Angiographie NNP cord-015369-72cjogxz 2673 10 kam kam NNP cord-015369-72cjogxz 2673 11 es es XX cord-015369-72cjogxz 2673 12 zu zu NNP cord-015369-72cjogxz 2673 13 einem einem NNP cord-015369-72cjogxz 2673 14 Lappenverlust Lappenverlust NNP cord-015369-72cjogxz 2673 15 . . . cord-015369-72cjogxz 2674 1 Die die VB cord-015369-72cjogxz 2674 2 Operationsdauer Operationsdauer NNP cord-015369-72cjogxz 2674 3 der der NNP cord-015369-72cjogxz 2674 4 Lappenhebung Lappenhebung NNP cord-015369-72cjogxz 2674 5 konnte konnte NNP cord-015369-72cjogxz 2674 6 verkürzt verkürzt NNP cord-015369-72cjogxz 2674 7 werden werden NNP cord-015369-72cjogxz 2674 8 , , , cord-015369-72cjogxz 2675 1 sowie sowie NNP cord-015369-72cjogxz 2675 2 das das NNP cord-015369-72cjogxz 2675 3 Lappendesign Lappendesign NNP cord-015369-72cjogxz 2675 4 anhand anhand NNP cord-015369-72cjogxz 2675 5 der der NNP cord-015369-72cjogxz 2675 6 Untersuchungsergebnisse Untersuchungsergebnisse NNP cord-015369-72cjogxz 2675 7 individuell individuell JJ cord-015369-72cjogxz 2675 8 angepasst angepasst NNP cord-015369-72cjogxz 2675 9 werden werden NNP cord-015369-72cjogxz 2675 10 . . . cord-015369-72cjogxz 2676 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 2676 2 . . . cord-015369-72cjogxz 2677 1 Die die VB cord-015369-72cjogxz 2677 2 präoperative präoperative NNP cord-015369-72cjogxz 2677 3 CT CT NNP cord-015369-72cjogxz 2677 4 - - HYPH cord-015369-72cjogxz 2677 5 Angiographie Angiographie NNP cord-015369-72cjogxz 2677 6 der der NNP cord-015369-72cjogxz 2677 7 Perforatorgefäße Perforatorgefäße NNP cord-015369-72cjogxz 2677 8 zur zur NNP cord-015369-72cjogxz 2677 9 Hebung Hebung NNP cord-015369-72cjogxz 2677 10 eines eines NNP cord-015369-72cjogxz 2678 1 DIEAP DIEAP NNP cord-015369-72cjogxz 2678 2 - - HYPH cord-015369-72cjogxz 2678 3 flap flap NN cord-015369-72cjogxz 2678 4 trägt trägt NNP cord-015369-72cjogxz 2678 5 zu zu NNP cord-015369-72cjogxz 2678 6 einer einer NNP cord-015369-72cjogxz 2679 1 Reduktion Reduktion NNP cord-015369-72cjogxz 2679 2 der der NNP cord-015369-72cjogxz 2679 3 Operationsdauer Operationsdauer NNP cord-015369-72cjogxz 2679 4 bei bei NNP cord-015369-72cjogxz 2680 1 und und IN cord-015369-72cjogxz 2680 2 hat hat NN cord-015369-72cjogxz 2680 3 einen einen NN cord-015369-72cjogxz 2680 4 positiven positiven NNP cord-015369-72cjogxz 2681 1 Einfluss Einfluss NNP cord-015369-72cjogxz 2681 2 auf auf NNS cord-015369-72cjogxz 2681 3 die die VBP cord-015369-72cjogxz 2682 1 Realibilität Realibilität NNP cord-015369-72cjogxz 2682 2 der der NNP cord-015369-72cjogxz 2682 3 Lappendurchblutung Lappendurchblutung NNP cord-015369-72cjogxz 2682 4 . . . cord-015369-72cjogxz 2683 1 Roughly roughly RB cord-015369-72cjogxz 2683 2 2 2 CD cord-015369-72cjogxz 2683 3 % % NN cord-015369-72cjogxz 2683 4 of of IN cord-015369-72cjogxz 2683 5 pediatric pediatric JJ cord-015369-72cjogxz 2683 6 tumors tumor NNS cord-015369-72cjogxz 2683 7 are be VBP cord-015369-72cjogxz 2683 8 present present JJ cord-015369-72cjogxz 2683 9 at at IN cord-015369-72cjogxz 2683 10 birth birth NN cord-015369-72cjogxz 2683 11 . . . cord-015369-72cjogxz 2684 1 With with IN cord-015369-72cjogxz 2684 2 the the DT cord-015369-72cjogxz 2684 3 increased increase VBN cord-015369-72cjogxz 2684 4 use use NN cord-015369-72cjogxz 2684 5 of of IN cord-015369-72cjogxz 2684 6 prenatal prenatal JJ cord-015369-72cjogxz 2684 7 imaging image VBG cord-015369-72cjogxz 2684 8 these these DT cord-015369-72cjogxz 2684 9 tumors tumor NNS cord-015369-72cjogxz 2684 10 are be VBP cord-015369-72cjogxz 2684 11 detected detect VBN cord-015369-72cjogxz 2684 12 at at IN cord-015369-72cjogxz 2684 13 earlier early JJR cord-015369-72cjogxz 2684 14 stages stage NNS cord-015369-72cjogxz 2684 15 of of IN cord-015369-72cjogxz 2684 16 fetal fetal JJ cord-015369-72cjogxz 2684 17 development development NN cord-015369-72cjogxz 2684 18 and and CC cord-015369-72cjogxz 2684 19 pose pose VBP cord-015369-72cjogxz 2684 20 a a DT cord-015369-72cjogxz 2684 21 diagnostic diagnostic JJ cord-015369-72cjogxz 2684 22 and and CC cord-015369-72cjogxz 2684 23 therapeutic therapeutic JJ cord-015369-72cjogxz 2684 24 challenge challenge NN cord-015369-72cjogxz 2684 25 as as IN cord-015369-72cjogxz 2684 26 of of IN cord-015369-72cjogxz 2684 27 how how WRB cord-015369-72cjogxz 2684 28 to to TO cord-015369-72cjogxz 2684 29 proceed proceed VB cord-015369-72cjogxz 2684 30 in in IN cord-015369-72cjogxz 2684 31 a a DT cord-015369-72cjogxz 2684 32 situation situation NN cord-015369-72cjogxz 2684 33 of of IN cord-015369-72cjogxz 2684 34 potential potential JJ cord-015369-72cjogxz 2684 35 malignant malignant JJ cord-015369-72cjogxz 2684 36 grow grow NN cord-015369-72cjogxz 2684 37 . . . cord-015369-72cjogxz 2685 1 Methods method NNS cord-015369-72cjogxz 2685 2 . . . cord-015369-72cjogxz 2686 1 If if IN cord-015369-72cjogxz 2686 2 on on IN cord-015369-72cjogxz 2686 3 routine routine JJ cord-015369-72cjogxz 2686 4 prenatal prenatal JJ cord-015369-72cjogxz 2686 5 ultrasound ultrasound NN cord-015369-72cjogxz 2686 6 a a DT cord-015369-72cjogxz 2686 7 tumor tumor NN cord-015369-72cjogxz 2686 8 was be VBD cord-015369-72cjogxz 2686 9 suspected suspect VBN cord-015369-72cjogxz 2686 10 , , , cord-015369-72cjogxz 2686 11 axial axial JJ cord-015369-72cjogxz 2686 12 , , , cord-015369-72cjogxz 2686 13 coronal coronal JJ cord-015369-72cjogxz 2686 14 and and CC cord-015369-72cjogxz 2686 15 sagittal sagittal JJ cord-015369-72cjogxz 2686 16 T1-w t1-w NN cord-015369-72cjogxz 2686 17 and and CC cord-015369-72cjogxz 2686 18 T2-w T2-w NNP cord-015369-72cjogxz 2686 19 sequences sequence NNS cord-015369-72cjogxz 2686 20 were be VBD cord-015369-72cjogxz 2686 21 obtained obtain VBN cord-015369-72cjogxz 2686 22 using use VBG cord-015369-72cjogxz 2686 23 a a DT cord-015369-72cjogxz 2686 24 1.5 1.5 CD cord-015369-72cjogxz 2686 25 Tesla Tesla NNP cord-015369-72cjogxz 2686 26 MRI MRI NNP cord-015369-72cjogxz 2686 27 . . . cord-015369-72cjogxz 2687 1 The the DT cord-015369-72cjogxz 2687 2 MRI MRI NNP cord-015369-72cjogxz 2687 3 's 's POS cord-015369-72cjogxz 2687 4 were be VBD cord-015369-72cjogxz 2687 5 performed perform VBN cord-015369-72cjogxz 2687 6 between between IN cord-015369-72cjogxz 2687 7 the the DT cord-015369-72cjogxz 2687 8 22nd-39th 22nd-39th JJ cord-015369-72cjogxz 2687 9 GW GW NNP cord-015369-72cjogxz 2687 10 ( ( -LRB- cord-015369-72cjogxz 2687 11 median median NN cord-015369-72cjogxz 2687 12 29 29 CD cord-015369-72cjogxz 2687 13 GW GW NNP cord-015369-72cjogxz 2687 14 ) ) -RRB- cord-015369-72cjogxz 2687 15 . . . cord-015369-72cjogxz 2688 1 No no DT cord-015369-72cjogxz 2688 2 sedation sedation NN cord-015369-72cjogxz 2688 3 or or CC cord-015369-72cjogxz 2688 4 contrast contrast NN cord-015369-72cjogxz 2688 5 enhancement enhancement NN cord-015369-72cjogxz 2688 6 was be VBD cord-015369-72cjogxz 2688 7 used use VBN cord-015369-72cjogxz 2688 8 for for IN cord-015369-72cjogxz 2688 9 this this DT cord-015369-72cjogxz 2688 10 study study NN cord-015369-72cjogxz 2688 11 . . . cord-015369-72cjogxz 2689 1 Results result NNS cord-015369-72cjogxz 2689 2 . . . cord-015369-72cjogxz 2690 1 Between between IN cord-015369-72cjogxz 2690 2 2001 2001 CD cord-015369-72cjogxz 2690 3 and and CC cord-015369-72cjogxz 2690 4 08 08 CD cord-015369-72cjogxz 2690 5 , , , cord-015369-72cjogxz 2690 6 10 10 CD cord-015369-72cjogxz 2690 7 tumors tumor NNS cord-015369-72cjogxz 2690 8 were be VBD cord-015369-72cjogxz 2690 9 diagnosed diagnose VBN cord-015369-72cjogxz 2690 10 after after IN cord-015369-72cjogxz 2690 11 exclusion exclusion NN cord-015369-72cjogxz 2690 12 of of IN cord-015369-72cjogxz 2690 13 hemangiomas hemangiomas NNP cord-015369-72cjogxz 2690 14 , , , cord-015369-72cjogxz 2690 15 lymphangiomas lymphangiomas NN cord-015369-72cjogxz 2690 16 , , , cord-015369-72cjogxz 2690 17 ovarian ovarian JJ cord-015369-72cjogxz 2690 18 cysts cyst NNS cord-015369-72cjogxz 2690 19 and and CC cord-015369-72cjogxz 2690 20 CCAM CCAM NNP cord-015369-72cjogxz 2690 21 . . . cord-015369-72cjogxz 2691 1 6 6 CD cord-015369-72cjogxz 2691 2 were be VBD cord-015369-72cjogxz 2691 3 teratomas teratoma NNS cord-015369-72cjogxz 2691 4 localized localize VBN cord-015369-72cjogxz 2691 5 to to IN cord-015369-72cjogxz 2691 6 the the DT cord-015369-72cjogxz 2691 7 face face NN cord-015369-72cjogxz 2691 8 ( ( -LRB- cord-015369-72cjogxz 2691 9 1 1 CD cord-015369-72cjogxz 2691 10 ) ) -RRB- cord-015369-72cjogxz 2691 11 , , , cord-015369-72cjogxz 2691 12 neck neck NN cord-015369-72cjogxz 2691 13 ( ( -LRB- cord-015369-72cjogxz 2691 14 2 2 CD cord-015369-72cjogxz 2691 15 ) ) -RRB- cord-015369-72cjogxz 2691 16 , , , cord-015369-72cjogxz 2691 17 mediastinum(1 mediastinum(1 LS cord-015369-72cjogxz 2691 18 ) ) -RRB- cord-015369-72cjogxz 2691 19 sacrococcyx(2 sacrococcyx(2 NNS cord-015369-72cjogxz 2691 20 ) ) -RRB- cord-015369-72cjogxz 2691 21 . . . cord-015369-72cjogxz 2692 1 The the DT cord-015369-72cjogxz 2692 2 remaining remain VBG cord-015369-72cjogxz 2692 3 tumors tumor NNS cord-015369-72cjogxz 2692 4 were be VBD cord-015369-72cjogxz 2692 5 a a DT cord-015369-72cjogxz 2692 6 hepatoblastoma hepatoblastoma NN cord-015369-72cjogxz 2692 7 , , , cord-015369-72cjogxz 2692 8 a a DT cord-015369-72cjogxz 2692 9 cystic cystic JJ cord-015369-72cjogxz 2692 10 neuroblastoma neuroblastoma NN cord-015369-72cjogxz 2692 11 , , , cord-015369-72cjogxz 2692 12 a a DT cord-015369-72cjogxz 2692 13 adrenal adrenal JJ cord-015369-72cjogxz 2692 14 cyst cyst NN cord-015369-72cjogxz 2692 15 and and CC cord-015369-72cjogxz 2692 16 a a DT cord-015369-72cjogxz 2692 17 malignant malignant JJ cord-015369-72cjogxz 2692 18 glioma glioma NN cord-015369-72cjogxz 2692 19 / / SYM cord-015369-72cjogxz 2692 20 PNET PNET NNP cord-015369-72cjogxz 2692 21 . . . cord-015369-72cjogxz 2693 1 Three three CD cord-015369-72cjogxz 2693 2 cases case NNS cord-015369-72cjogxz 2693 3 posed pose VBD cord-015369-72cjogxz 2693 4 a a DT cord-015369-72cjogxz 2693 5 special special JJ cord-015369-72cjogxz 2693 6 therapeutic therapeutic JJ cord-015369-72cjogxz 2693 7 dilemma dilemma NN cord-015369-72cjogxz 2693 8 . . . cord-015369-72cjogxz 2694 1 The the DT cord-015369-72cjogxz 2694 2 facial facial JJ cord-015369-72cjogxz 2694 3 teratoma teratoma NN cord-015369-72cjogxz 2694 4 that that IN cord-015369-72cjogxz 2694 5 due due JJ cord-015369-72cjogxz 2694 6 to to IN cord-015369-72cjogxz 2694 7 rapid rapid JJ cord-015369-72cjogxz 2694 8 tumor tumor NN cord-015369-72cjogxz 2694 9 growth growth NN cord-015369-72cjogxz 2694 10 had have VBD cord-015369-72cjogxz 2694 11 to to TO cord-015369-72cjogxz 2694 12 be be VB cord-015369-72cjogxz 2694 13 delivered deliver VBN cord-015369-72cjogxz 2694 14 by by IN cord-015369-72cjogxz 2694 15 C c NN cord-015369-72cjogxz 2694 16 - - HYPH cord-015369-72cjogxz 2694 17 section section NN cord-015369-72cjogxz 2694 18 at at IN cord-015369-72cjogxz 2694 19 30 30 CD cord-015369-72cjogxz 2694 20 GW GW NNP cord-015369-72cjogxz 2694 21 so so IN cord-015369-72cjogxz 2694 22 that that IN cord-015369-72cjogxz 2694 23 chemotherapy chemotherapy NN cord-015369-72cjogxz 2694 24 could could MD cord-015369-72cjogxz 2694 25 be be VB cord-015369-72cjogxz 2694 26 initiated initiate VBN cord-015369-72cjogxz 2694 27 . . . cord-015369-72cjogxz 2695 1 One one CD cord-015369-72cjogxz 2695 2 of of IN cord-015369-72cjogxz 2695 3 the the DT cord-015369-72cjogxz 2695 4 cervical cervical JJ cord-015369-72cjogxz 2695 5 immature immature JJ cord-015369-72cjogxz 2695 6 teratomas teratomas NNPS cord-015369-72cjogxz 2695 7 had have VBD cord-015369-72cjogxz 2695 8 rapid rapid JJ cord-015369-72cjogxz 2695 9 extension extension NN cord-015369-72cjogxz 2695 10 and and CC cord-015369-72cjogxz 2695 11 should should MD cord-015369-72cjogxz 2695 12 have have VB cord-015369-72cjogxz 2695 13 been be VBN cord-015369-72cjogxz 2695 14 delivered deliver VBN cord-015369-72cjogxz 2695 15 earlier early RBR cord-015369-72cjogxz 2695 16 . . . cord-015369-72cjogxz 2696 1 The the DT cord-015369-72cjogxz 2696 2 fetus fetus NN cord-015369-72cjogxz 2696 3 with with IN cord-015369-72cjogxz 2696 4 hepatoblastoma hepatoblastoma NNP cord-015369-72cjogxz 2696 5 had have VBD cord-015369-72cjogxz 2696 6 rapid rapid JJ cord-015369-72cjogxz 2696 7 tumor tumor NN cord-015369-72cjogxz 2696 8 progression progression NN cord-015369-72cjogxz 2696 9 and and CC cord-015369-72cjogxz 2696 10 required require VBD cord-015369-72cjogxz 2696 11 a a DT cord-015369-72cjogxz 2696 12 hemihepatectomy hemihepatectomy NN cord-015369-72cjogxz 2696 13 in in IN cord-015369-72cjogxz 2696 14 the the DT cord-015369-72cjogxz 2696 15 first first JJ cord-015369-72cjogxz 2696 16 week week NN cord-015369-72cjogxz 2696 17 of of IN cord-015369-72cjogxz 2696 18 life life NN cord-015369-72cjogxz 2696 19 . . . cord-015369-72cjogxz 2697 1 Conclusions conclusion NNS cord-015369-72cjogxz 2697 2 . . . cord-015369-72cjogxz 2698 1 Prenatally Prenatally NNP cord-015369-72cjogxz 2698 2 detected detect VBD cord-015369-72cjogxz 2698 3 tumors tumor NNS cord-015369-72cjogxz 2698 4 pose pose VBP cord-015369-72cjogxz 2698 5 a a DT cord-015369-72cjogxz 2698 6 diagnostic diagnostic JJ cord-015369-72cjogxz 2698 7 and and CC cord-015369-72cjogxz 2698 8 therapeutic therapeutic JJ cord-015369-72cjogxz 2698 9 challenge challenge NN cord-015369-72cjogxz 2698 10 . . . cord-015369-72cjogxz 2699 1 Location location NN cord-015369-72cjogxz 2699 2 , , , cord-015369-72cjogxz 2699 3 size size NN cord-015369-72cjogxz 2699 4 , , , cord-015369-72cjogxz 2699 5 extension extension NN cord-015369-72cjogxz 2699 6 and and CC cord-015369-72cjogxz 2699 7 vascularity vascularity NN cord-015369-72cjogxz 2699 8 of of IN cord-015369-72cjogxz 2699 9 the the DT cord-015369-72cjogxz 2699 10 tumor tumor NN cord-015369-72cjogxz 2699 11 will will MD cord-015369-72cjogxz 2699 12 determine determine VB cord-015369-72cjogxz 2699 13 the the DT cord-015369-72cjogxz 2699 14 viability viability NN cord-015369-72cjogxz 2699 15 of of IN cord-015369-72cjogxz 2699 16 the the DT cord-015369-72cjogxz 2699 17 fetus fetus NN cord-015369-72cjogxz 2699 18 and and CC cord-015369-72cjogxz 2699 19 therapeutic therapeutic JJ cord-015369-72cjogxz 2699 20 options option NNS cord-015369-72cjogxz 2699 21 including include VBG cord-015369-72cjogxz 2699 22 time time NN cord-015369-72cjogxz 2699 23 and and CC cord-015369-72cjogxz 2699 24 mode mode NN cord-015369-72cjogxz 2699 25 of of IN cord-015369-72cjogxz 2699 26 delivery delivery NN cord-015369-72cjogxz 2699 27 . . . cord-015369-72cjogxz 2700 1 Consensus consensus NN cord-015369-72cjogxz 2700 2 has have VBZ cord-015369-72cjogxz 2700 3 to to TO cord-015369-72cjogxz 2700 4 be be VB cord-015369-72cjogxz 2700 5 taken take VBN cord-015369-72cjogxz 2700 6 by by IN cord-015369-72cjogxz 2700 7 an an DT cord-015369-72cjogxz 2700 8 interdisciplinary interdisciplinary JJ cord-015369-72cjogxz 2700 9 team team NN cord-015369-72cjogxz 2700 10 ( ( -LRB- cord-015369-72cjogxz 2700 11 obstetrician obstetrician NN cord-015369-72cjogxz 2700 12 , , , cord-015369-72cjogxz 2700 13 neonatologist neonatologist NN cord-015369-72cjogxz 2700 14 , , , cord-015369-72cjogxz 2700 15 oncologist oncologist NN cord-015369-72cjogxz 2700 16 , , , cord-015369-72cjogxz 2700 17 surgeon surgeon NN cord-015369-72cjogxz 2700 18 ) ) -RRB- cord-015369-72cjogxz 2700 19 and and CC cord-015369-72cjogxz 2700 20 the the DT cord-015369-72cjogxz 2700 21 parents parent NNS cord-015369-72cjogxz 2700 22 . . . cord-015369-72cjogxz 2701 1 Background background NN cord-015369-72cjogxz 2701 2 . . . cord-015369-72cjogxz 2702 1 Burns burn NNS cord-015369-72cjogxz 2702 2 are be VBP cord-015369-72cjogxz 2702 3 very very RB cord-015369-72cjogxz 2702 4 common common JJ cord-015369-72cjogxz 2702 5 in in IN cord-015369-72cjogxz 2702 6 pediatric pediatric JJ cord-015369-72cjogxz 2702 7 patients patient NNS cord-015369-72cjogxz 2702 8 . . . cord-015369-72cjogxz 2703 1 Most Most JJS cord-015369-72cjogxz 2703 2 children child NNS cord-015369-72cjogxz 2703 3 are be VBP cord-015369-72cjogxz 2703 4 very very RB cord-015369-72cjogxz 2703 5 young young JJ cord-015369-72cjogxz 2703 6 ( ( -LRB- cord-015369-72cjogxz 2703 7 < < XX cord-015369-72cjogxz 2703 8 3 3 CD cord-015369-72cjogxz 2703 9 years year NNS cord-015369-72cjogxz 2703 10 of of IN cord-015369-72cjogxz 2703 11 age age NN cord-015369-72cjogxz 2703 12 ) ) -RRB- cord-015369-72cjogxz 2703 13 . . . cord-015369-72cjogxz 2704 1 A a DT cord-015369-72cjogxz 2704 2 variety variety NN cord-015369-72cjogxz 2704 3 of of IN cord-015369-72cjogxz 2704 4 none none NN cord-015369-72cjogxz 2704 5 degradable degradable JJ cord-015369-72cjogxz 2704 6 products product NNS cord-015369-72cjogxz 2704 7 are be VBP cord-015369-72cjogxz 2704 8 available available JJ cord-015369-72cjogxz 2704 9 for for IN cord-015369-72cjogxz 2704 10 closed closed JJ cord-015369-72cjogxz 2704 11 wound wound NN cord-015369-72cjogxz 2704 12 management management NN cord-015369-72cjogxz 2704 13 . . . cord-015369-72cjogxz 2705 1 Suprathel Suprathel NNP cord-015369-72cjogxz 2705 2 TM TM NNP cord-015369-72cjogxz 2705 3 is be VBZ cord-015369-72cjogxz 2705 4 a a DT cord-015369-72cjogxz 2705 5 degradable degradable JJ cord-015369-72cjogxz 2705 6 alternative alternative NN cord-015369-72cjogxz 2705 7 . . . cord-015369-72cjogxz 2706 1 It -PRON- PRP cord-015369-72cjogxz 2706 2 is be VBZ cord-015369-72cjogxz 2706 3 composed compose VBN cord-015369-72cjogxz 2706 4 of of IN cord-015369-72cjogxz 2706 5 polylactic polylactic JJ cord-015369-72cjogxz 2706 6 acid acid NN cord-015369-72cjogxz 2706 7 in in IN cord-015369-72cjogxz 2706 8 combination combination NN cord-015369-72cjogxz 2706 9 with with IN cord-015369-72cjogxz 2706 10 other other JJ cord-015369-72cjogxz 2706 11 biocompatible biocompatible JJ cord-015369-72cjogxz 2706 12 polymers polymer NNS cord-015369-72cjogxz 2706 13 . . . cord-015369-72cjogxz 2707 1 It -PRON- PRP cord-015369-72cjogxz 2707 2 can can MD cord-015369-72cjogxz 2707 3 be be VB cord-015369-72cjogxz 2707 4 used use VBN cord-015369-72cjogxz 2707 5 for for IN cord-015369-72cjogxz 2707 6 2nd 2nd JJ cord-015369-72cjogxz 2707 7 and and CC cord-015369-72cjogxz 2707 8 partial partial JJ cord-015369-72cjogxz 2707 9 3rd 3rd JJ cord-015369-72cjogxz 2707 10 degree degree NN cord-015369-72cjogxz 2707 11 burns burn NNS cord-015369-72cjogxz 2707 12 , , , cord-015369-72cjogxz 2707 13 split split VBD cord-015369-72cjogxz 2707 14 skin skin NN cord-015369-72cjogxz 2707 15 donor donor NN cord-015369-72cjogxz 2707 16 sites site NNS cord-015369-72cjogxz 2707 17 and and CC cord-015369-72cjogxz 2707 18 large large JJ cord-015369-72cjogxz 2707 19 - - HYPH cord-015369-72cjogxz 2707 20 area area NN cord-015369-72cjogxz 2707 21 abrasions abrasion NNS cord-015369-72cjogxz 2707 22 . . . cord-015369-72cjogxz 2708 1 Methods method NNS cord-015369-72cjogxz 2708 2 . . . cord-015369-72cjogxz 2709 1 Between between IN cord-015369-72cjogxz 2709 2 November November NNP cord-015369-72cjogxz 2709 3 2006 2006 CD cord-015369-72cjogxz 2709 4 and and CC cord-015369-72cjogxz 2709 5 November November NNP cord-015369-72cjogxz 2709 6 2008 2008 CD cord-015369-72cjogxz 2709 7 , , , cord-015369-72cjogxz 2709 8 we -PRON- PRP cord-015369-72cjogxz 2709 9 treated treat VBD cord-015369-72cjogxz 2709 10 123 123 CD cord-015369-72cjogxz 2709 11 children child NNS cord-015369-72cjogxz 2709 12 between between IN cord-015369-72cjogxz 2709 13 2 2 CD cord-015369-72cjogxz 2709 14 months month NNS cord-015369-72cjogxz 2709 15 and and CC cord-015369-72cjogxz 2709 16 16 16 CD cord-015369-72cjogxz 2709 17 years year NNS cord-015369-72cjogxz 2709 18 of of IN cord-015369-72cjogxz 2709 19 age age NN cord-015369-72cjogxz 2709 20 , , , cord-015369-72cjogxz 2709 21 most most JJS cord-015369-72cjogxz 2709 22 of of IN cord-015369-72cjogxz 2709 23 them -PRON- PRP cord-015369-72cjogxz 2709 24 with with IN cord-015369-72cjogxz 2709 25 2a 2a CD cord-015369-72cjogxz 2709 26 and and CC cord-015369-72cjogxz 2709 27 2b 2b NNP cord-015369-72cjogxz 2709 28 burns burn NNS cord-015369-72cjogxz 2709 29 . . . cord-015369-72cjogxz 2710 1 Suprathel Suprathel NNP cord-015369-72cjogxz 2710 2 TM TM NNP cord-015369-72cjogxz 2710 3 was be VBD cord-015369-72cjogxz 2710 4 used use VBN cord-015369-72cjogxz 2710 5 in in IN cord-015369-72cjogxz 2710 6 74 74 CD cord-015369-72cjogxz 2710 7 cases case NNS cord-015369-72cjogxz 2710 8 ( ( -LRB- cord-015369-72cjogxz 2710 9 60 60 CD cord-015369-72cjogxz 2710 10 % % NN cord-015369-72cjogxz 2710 11 ) ) -RRB- cord-015369-72cjogxz 2710 12 . . . cord-015369-72cjogxz 2711 1 Debridement Debridement NNP cord-015369-72cjogxz 2711 2 was be VBD cord-015369-72cjogxz 2711 3 performed perform VBN cord-015369-72cjogxz 2711 4 without without IN cord-015369-72cjogxz 2711 5 undue undue JJ cord-015369-72cjogxz 2711 6 delay delay NN cord-015369-72cjogxz 2711 7 . . . cord-015369-72cjogxz 2712 1 Three three CD cord-015369-72cjogxz 2712 2 days day NNS cord-015369-72cjogxz 2712 3 later later RB cord-015369-72cjogxz 2712 4 we -PRON- PRP cord-015369-72cjogxz 2712 5 applied apply VBD cord-015369-72cjogxz 2712 6 Suprathel Suprathel NNP cord-015369-72cjogxz 2712 7 TM TM NNP cord-015369-72cjogxz 2712 8 and and CC cord-015369-72cjogxz 2712 9 two two CD cord-015369-72cjogxz 2712 10 layers layer NNS cord-015369-72cjogxz 2712 11 of of IN cord-015369-72cjogxz 2712 12 fat fat JJ cord-015369-72cjogxz 2712 13 gauze gauze NN cord-015369-72cjogxz 2712 14 to to TO cord-015369-72cjogxz 2712 15 prevent prevent VB cord-015369-72cjogxz 2712 16 adhesions adhesion NNS cord-015369-72cjogxz 2712 17 . . . cord-015369-72cjogxz 2713 1 In in IN cord-015369-72cjogxz 2713 2 2 2 CD cord-015369-72cjogxz 2713 3 to to TO cord-015369-72cjogxz 2713 4 5 5 CD cord-015369-72cjogxz 2713 5 days day NNS cord-015369-72cjogxz 2713 6 intervals interval NNS cord-015369-72cjogxz 2713 7 the the DT cord-015369-72cjogxz 2713 8 superficial superficial JJ cord-015369-72cjogxz 2713 9 dressing dressing NN cord-015369-72cjogxz 2713 10 was be VBD cord-015369-72cjogxz 2713 11 changed change VBN cord-015369-72cjogxz 2713 12 , , , cord-015369-72cjogxz 2713 13 leaving leave VBG cord-015369-72cjogxz 2713 14 Suprathel Suprathel NNP cord-015369-72cjogxz 2713 15 TM TM NNP cord-015369-72cjogxz 2713 16 and and CC cord-015369-72cjogxz 2713 17 the the DT cord-015369-72cjogxz 2713 18 deeper deep JJR cord-015369-72cjogxz 2713 19 gauze gauze NN cord-015369-72cjogxz 2713 20 in in IN cord-015369-72cjogxz 2713 21 place place NN cord-015369-72cjogxz 2713 22 . . . cord-015369-72cjogxz 2714 1 Results result NNS cord-015369-72cjogxz 2714 2 . . . cord-015369-72cjogxz 2715 1 Changing change VBG cord-015369-72cjogxz 2715 2 of of IN cord-015369-72cjogxz 2715 3 the the DT cord-015369-72cjogxz 2715 4 superficial superficial JJ cord-015369-72cjogxz 2715 5 dressing dressing NN cord-015369-72cjogxz 2715 6 was be VBD cord-015369-72cjogxz 2715 7 easy easy JJ cord-015369-72cjogxz 2715 8 and and CC cord-015369-72cjogxz 2715 9 painless painless JJ cord-015369-72cjogxz 2715 10 . . . cord-015369-72cjogxz 2716 1 Inspection inspection NN cord-015369-72cjogxz 2716 2 of of IN cord-015369-72cjogxz 2716 3 the the DT cord-015369-72cjogxz 2716 4 healing healing NN cord-015369-72cjogxz 2716 5 progress progress NN cord-015369-72cjogxz 2716 6 was be VBD cord-015369-72cjogxz 2716 7 possible possible JJ cord-015369-72cjogxz 2716 8 as as IN cord-015369-72cjogxz 2716 9 Suprathel Suprathel NNP cord-015369-72cjogxz 2716 10 TM TM NNP cord-015369-72cjogxz 2716 11 becomes become VBZ cord-015369-72cjogxz 2716 12 translucent translucent JJ cord-015369-72cjogxz 2716 13 . . . cord-015369-72cjogxz 2717 1 Time time NN cord-015369-72cjogxz 2717 2 spent spend VBN cord-015369-72cjogxz 2717 3 in in IN cord-015369-72cjogxz 2717 4 hospital hospital NN cord-015369-72cjogxz 2717 5 was be VBD cord-015369-72cjogxz 2717 6 reduced reduce VBN cord-015369-72cjogxz 2717 7 , , , cord-015369-72cjogxz 2717 8 wound wind VBN cord-015369-72cjogxz 2717 9 healing healing NN cord-015369-72cjogxz 2717 10 speeded speed VBD cord-015369-72cjogxz 2717 11 up up RP cord-015369-72cjogxz 2717 12 , , , cord-015369-72cjogxz 2717 13 no no DT cord-015369-72cjogxz 2717 14 wound wound NN cord-015369-72cjogxz 2717 15 infection infection NN cord-015369-72cjogxz 2717 16 was be VBD cord-015369-72cjogxz 2717 17 recorded record VBN cord-015369-72cjogxz 2717 18 and and CC cord-015369-72cjogxz 2717 19 the the DT cord-015369-72cjogxz 2717 20 cosmetic cosmetic JJ cord-015369-72cjogxz 2717 21 results result NNS cord-015369-72cjogxz 2717 22 were be VBD cord-015369-72cjogxz 2717 23 excellent excellent JJ cord-015369-72cjogxz 2717 24 . . . cord-015369-72cjogxz 2718 1 Suprathel Suprathel NNP cord-015369-72cjogxz 2718 2 TM TM NNP cord-015369-72cjogxz 2718 3 came come VBD cord-015369-72cjogxz 2718 4 off off RP cord-015369-72cjogxz 2718 5 naturally naturally RB cord-015369-72cjogxz 2718 6 within within IN cord-015369-72cjogxz 2718 7 10 10 CD cord-015369-72cjogxz 2718 8 to to TO cord-015369-72cjogxz 2718 9 12 12 CD cord-015369-72cjogxz 2718 10 days day NNS cord-015369-72cjogxz 2718 11 after after IN cord-015369-72cjogxz 2718 12 application application NN cord-015369-72cjogxz 2718 13 . . . cord-015369-72cjogxz 2719 1 Discoloration discoloration NN cord-015369-72cjogxz 2719 2 of of IN cord-015369-72cjogxz 2719 3 the the DT cord-015369-72cjogxz 2719 4 overlying overlying JJ cord-015369-72cjogxz 2719 5 fat fat JJ cord-015369-72cjogxz 2719 6 gauze gauze NN cord-015369-72cjogxz 2719 7 was be VBD cord-015369-72cjogxz 2719 8 observed observe VBN cord-015369-72cjogxz 2719 9 and and CC cord-015369-72cjogxz 2719 10 was be VBD cord-015369-72cjogxz 2719 11 never never RB cord-015369-72cjogxz 2719 12 caused cause VBN cord-015369-72cjogxz 2719 13 by by IN cord-015369-72cjogxz 2719 14 infection infection NN cord-015369-72cjogxz 2719 15 . . . cord-015369-72cjogxz 2720 1 Occasionally occasionally RB cord-015369-72cjogxz 2720 2 Suprathel Suprathel NNP cord-015369-72cjogxz 2720 3 TM TM NNP cord-015369-72cjogxz 2720 4 did do VBD cord-015369-72cjogxz 2720 5 not not RB cord-015369-72cjogxz 2720 6 adhere adhere VB cord-015369-72cjogxz 2720 7 initially initially RB cord-015369-72cjogxz 2720 8 . . . cord-015369-72cjogxz 2721 1 Conclusions conclusion NNS cord-015369-72cjogxz 2721 2 . . . cord-015369-72cjogxz 2722 1 Suprathel Suprathel NNP cord-015369-72cjogxz 2722 2 TM TM NNP cord-015369-72cjogxz 2722 3 handling handling NN cord-015369-72cjogxz 2722 4 is be VBZ cord-015369-72cjogxz 2722 5 very very RB cord-015369-72cjogxz 2722 6 simple simple JJ cord-015369-72cjogxz 2722 7 . . . cord-015369-72cjogxz 2723 1 The the DT cord-015369-72cjogxz 2723 2 most most RBS cord-015369-72cjogxz 2723 3 important important JJ cord-015369-72cjogxz 2723 4 benefits benefit NNS cord-015369-72cjogxz 2723 5 are be VBP cord-015369-72cjogxz 2723 6 no no DT cord-015369-72cjogxz 2723 7 pain pain NN cord-015369-72cjogxz 2723 8 and and CC cord-015369-72cjogxz 2723 9 less less JJR cord-015369-72cjogxz 2723 10 change change NN cord-015369-72cjogxz 2723 11 of of IN cord-015369-72cjogxz 2723 12 dressing dress VBG cord-015369-72cjogxz 2723 13 with with IN cord-015369-72cjogxz 2723 14 good good JJ cord-015369-72cjogxz 2723 15 cosmetic cosmetic JJ cord-015369-72cjogxz 2723 16 results result NNS cord-015369-72cjogxz 2723 17 . . . cord-015369-72cjogxz 2724 1 It -PRON- PRP cord-015369-72cjogxz 2724 2 is be VBZ cord-015369-72cjogxz 2724 3 a a DT cord-015369-72cjogxz 2724 4 considerable considerable JJ cord-015369-72cjogxz 2724 5 improvement improvement NN cord-015369-72cjogxz 2724 6 of of IN cord-015369-72cjogxz 2724 7 the the DT cord-015369-72cjogxz 2724 8 management management NN cord-015369-72cjogxz 2724 9 of of IN cord-015369-72cjogxz 2724 10 2nd 2nd JJ cord-015369-72cjogxz 2724 11 and and CC cord-015369-72cjogxz 2724 12 partial partial JJ cord-015369-72cjogxz 2724 13 3rd 3rd JJ cord-015369-72cjogxz 2724 14 degree degree NN cord-015369-72cjogxz 2724 15 burns burn NNS cord-015369-72cjogxz 2724 16 in in IN cord-015369-72cjogxz 2724 17 children child NNS cord-015369-72cjogxz 2724 18 . . . cord-015369-72cjogxz 2725 1 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 2725 2 in in IN cord-015369-72cjogxz 2725 3 der der NNP cord-015369-72cjogxz 2725 4 Kinderwundambulanz Kinderwundambulanz NNP cord-015369-72cjogxz 2725 5 der der NNP cord-015369-72cjogxz 2725 6 Kinderchirurgischen Kinderchirurgischen NNP cord-015369-72cjogxz 2725 7 Abteilung Abteilung NNP cord-015369-72cjogxz 2725 8 der der NNP cord-015369-72cjogxz 2725 9 LFKK LFKK NNP cord-015369-72cjogxz 2725 10 Linz Linz NNP cord-015369-72cjogxz 2725 11 Grundlagen Grundlagen NNP cord-015369-72cjogxz 2725 12 . . . cord-015369-72cjogxz 2726 1 Eine Eine NNP cord-015369-72cjogxz 2726 2 der der NNP cord-015369-72cjogxz 2726 3 potentiellen potentiellen NNP cord-015369-72cjogxz 2726 4 Anwendungen Anwendungen NNP cord-015369-72cjogxz 2726 5 des des FW cord-015369-72cjogxz 2726 6 Monitorings Monitorings NNP cord-015369-72cjogxz 2727 1 von von NNP cord-015369-72cjogxz 2727 2 Angiogeneseparametern Angiogeneseparametern NNP cord-015369-72cjogxz 2727 3 ist ist NN cord-015369-72cjogxz 2727 4 die die VBP cord-015369-72cjogxz 2727 5 Verwendung Verwendung NNP cord-015369-72cjogxz 2727 6 als als NN cord-015369-72cjogxz 2727 7 Tumormarker Tumormarker NNP cord-015369-72cjogxz 2727 8 . . . cord-015369-72cjogxz 2728 1 Ziel Ziel NNP cord-015369-72cjogxz 2728 2 dieser dieser NNP cord-015369-72cjogxz 2728 3 Studie Studie NNP cord-015369-72cjogxz 2728 4 ist ist NNP cord-015369-72cjogxz 2728 5 , , , cord-015369-72cjogxz 2728 6 etablierte etablierte NNP cord-015369-72cjogxz 2728 7 Tumormarker Tumormarker NNP cord-015369-72cjogxz 2728 8 wie wie NNP cord-015369-72cjogxz 2728 9 CA CA NNP cord-015369-72cjogxz 2728 10 19 19 CD cord-015369-72cjogxz 2728 11 - - SYM cord-015369-72cjogxz 2728 12 9 9 CD cord-015369-72cjogxz 2729 1 den den NNP cord-015369-72cjogxz 2729 2 Angiogeneseparametern Angiogeneseparametern NNP cord-015369-72cjogxz 2730 1 unter unter JJ cord-015369-72cjogxz 2730 2 neoadjuvanter neoadjuvanter NNP cord-015369-72cjogxz 2730 3 Therapie Therapie NNP cord-015369-72cjogxz 2730 4 mit mit NNP cord-015369-72cjogxz 2730 5 Bevacizumab Bevacizumab NNP cord-015369-72cjogxz 2730 6 gegenüberzustellen gegenüberzustellen NNP cord-015369-72cjogxz 2730 7 . . . cord-015369-72cjogxz 2731 1 Untersucht Untersucht NNP cord-015369-72cjogxz 2731 2 wurden wurden VBD cord-015369-72cjogxz 2731 3 der der NNP cord-015369-72cjogxz 2731 4 pro pro JJ cord-015369-72cjogxz 2731 5 - - JJ cord-015369-72cjogxz 2731 6 angiogene angiogene JJ cord-015369-72cjogxz 2731 7 Faktor Faktor NNP cord-015369-72cjogxz 2731 8 VEGF VEGF NNP cord-015369-72cjogxz 2731 9 ( ( -LRB- cord-015369-72cjogxz 2731 10 vascular vascular JJ cord-015369-72cjogxz 2731 11 endothelial endothelial JJ cord-015369-72cjogxz 2731 12 growth growth NN cord-015369-72cjogxz 2731 13 factor factor NN cord-015369-72cjogxz 2731 14 ) ) -RRB- cord-015369-72cjogxz 2731 15 , , , cord-015369-72cjogxz 2731 16 der der NNP cord-015369-72cjogxz 2731 17 durch durch NNP cord-015369-72cjogxz 2731 18 Bevacizumab Bevacizumab NNP cord-015369-72cjogxz 2731 19 inaktiviert inaktiviert NNP cord-015369-72cjogxz 2731 20 wird wird NNP cord-015369-72cjogxz 2731 21 , , , cord-015369-72cjogxz 2732 1 sowie sowie NNP cord-015369-72cjogxz 2732 2 der der NNP cord-015369-72cjogxz 2732 3 Angiogeneseinhibitor Angiogeneseinhibitor NNP cord-015369-72cjogxz 2732 4 TSP-1 TSP-1 NNP cord-015369-72cjogxz 2732 5 ( ( -LRB- cord-015369-72cjogxz 2732 6 Thrombospondin-1 Thrombospondin-1 NNP cord-015369-72cjogxz 2732 7 ) ) -RRB- cord-015369-72cjogxz 2732 8 . . . cord-015369-72cjogxz 2733 1 Methodik Methodik NNP cord-015369-72cjogxz 2733 2 . . . cord-015369-72cjogxz 2734 1 19 19 CD cord-015369-72cjogxz 2735 1 Patienten Patienten NNP cord-015369-72cjogxz 2735 2 mit mit NNP cord-015369-72cjogxz 2735 3 lokal lokal NNP cord-015369-72cjogxz 2735 4 fortgeschrittenem fortgeschrittenem NNP cord-015369-72cjogxz 2735 5 Pankreaskarzinom Pankreaskarzinom NNP cord-015369-72cjogxz 2735 6 wurden wurden VBD cord-015369-72cjogxz 2735 7 mit mit NNP cord-015369-72cjogxz 2735 8 4 4 CD cord-015369-72cjogxz 2735 9 Zyklen Zyklen NNP cord-015369-72cjogxz 2735 10 ( ( -LRB- cord-015369-72cjogxz 2735 11 q q NNP cord-015369-72cjogxz 2735 12 4 4 CD cord-015369-72cjogxz 2735 13 Wochen Wochen NNP cord-015369-72cjogxz 2735 14 ) ) -RRB- cord-015369-72cjogxz 2736 1 Gemcitabin Gemcitabin NNP cord-015369-72cjogxz 2736 2 sowie sowie NNP cord-015369-72cjogxz 2736 3 2-wöchentlich 2-wöchentlich CD cord-015369-72cjogxz 2736 4 mit mit NNP cord-015369-72cjogxz 2736 5 Bevacizumab Bevacizumab NNP cord-015369-72cjogxz 2736 6 behandelt behandelt NNP cord-015369-72cjogxz 2736 7 . . . cord-015369-72cjogxz 2737 1 Blutproben Blutproben NNP cord-015369-72cjogxz 2737 2 wurden wurden VBD cord-015369-72cjogxz 2737 3 alle alle NNP cord-015369-72cjogxz 2737 4 2 2 CD cord-015369-72cjogxz 2737 5 Wochen Wochen NNP cord-015369-72cjogxz 2737 6 jeweils jeweils NNP cord-015369-72cjogxz 2737 7 direkt direkt NN cord-015369-72cjogxz 2737 8 vor vor NN cord-015369-72cjogxz 2737 9 der der NNP cord-015369-72cjogxz 2737 10 Bevacizumab Bevacizumab NNP cord-015369-72cjogxz 2737 11 - - HYPH cord-015369-72cjogxz 2737 12 Applikation Applikation NNP cord-015369-72cjogxz 2737 13 abgenommen abgenomman NNS cord-015369-72cjogxz 2737 14 . . . cord-015369-72cjogxz 2738 1 Die die VB cord-015369-72cjogxz 2738 2 Angiogenesefaktoren Angiogenesefaktoren NNP cord-015369-72cjogxz 2738 3 wurden wurden VBD cord-015369-72cjogxz 2738 4 i -PRON- PRP cord-015369-72cjogxz 2738 5 m be VBP cord-015369-72cjogxz 2738 6 Plasma Plasma NNP cord-015369-72cjogxz 2738 7 bestimmt bestimmt NNP cord-015369-72cjogxz 2738 8 . . . cord-015369-72cjogxz 2739 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2739 2 . . . cord-015369-72cjogxz 2740 1 I -PRON- PRP cord-015369-72cjogxz 2741 1 m m NNP cord-015369-72cjogxz 2741 2 Verlauf Verlauf NNP cord-015369-72cjogxz 2741 3 der der NNP cord-015369-72cjogxz 2741 4 Therapie Therapie NNP cord-015369-72cjogxz 2741 5 kam kam NNP cord-015369-72cjogxz 2741 6 es es XX cord-015369-72cjogxz 2741 7 zu zu NNP cord-015369-72cjogxz 2742 1 einem einem NNP cord-015369-72cjogxz 2742 2 kontinuierlichem kontinuierlichem NNP cord-015369-72cjogxz 2743 1 Abfall Abfall NNP cord-015369-72cjogxz 2743 2 von von NNP cord-015369-72cjogxz 2743 3 CA CA NNP cord-015369-72cjogxz 2743 4 19 19 CD cord-015369-72cjogxz 2743 5 - - SYM cord-015369-72cjogxz 2743 6 9 9 CD cord-015369-72cjogxz 2744 1 ( ( -LRB- cord-015369-72cjogxz 2744 2 p p NN cord-015369-72cjogxz 2744 3 ¼ ¼ NNP cord-015369-72cjogxz 2744 4 0,025 0,025 CD cord-015369-72cjogxz 2744 5 ) ) -RRB- cord-015369-72cjogxz 2744 6 . . . cord-015369-72cjogxz 2745 1 Die die VB cord-015369-72cjogxz 2746 1 VEGF VEGF NNP cord-015369-72cjogxz 2746 2 - - HYPH cord-015369-72cjogxz 2746 3 Spiegel Spiegel NNP cord-015369-72cjogxz 2746 4 korrelierten korrelierten NNP cord-015369-72cjogxz 2746 5 positiv positiv NNP cord-015369-72cjogxz 2746 6 mit mit NNP cord-015369-72cjogxz 2746 7 der der NNP cord-015369-72cjogxz 2746 8 Bevacizumab Bevacizumab NNP cord-015369-72cjogxz 2746 9 - - HYPH cord-015369-72cjogxz 2746 10 Therapie Therapie NNP cord-015369-72cjogxz 2746 11 und und NNP cord-015369-72cjogxz 2747 1 stiegen stiegen NNP cord-015369-72cjogxz 2747 2 bereits bereits NNP cord-015369-72cjogxz 2747 3 mit mit NNP cord-015369-72cjogxz 2747 4 der der NNP cord-015369-72cjogxz 2747 5 ersten ersten NNP cord-015369-72cjogxz 2747 6 Behandlung Behandlung NNP cord-015369-72cjogxz 2747 7 signifikant signifikant VB cord-015369-72cjogxz 2747 8 an an DT cord-015369-72cjogxz 2748 1 ( ( -LRB- cord-015369-72cjogxz 2748 2 p p NN cord-015369-72cjogxz 2748 3 ¼ ¼ CD cord-015369-72cjogxz 2748 4 0,004 0,004 CD cord-015369-72cjogxz 2748 5 Background Background NNP cord-015369-72cjogxz 2748 6 . . . cord-015369-72cjogxz 2749 1 Endoscopic endoscopic JJ cord-015369-72cjogxz 2749 2 thoracic thoracic JJ cord-015369-72cjogxz 2749 3 sympathetic sympathetic JJ cord-015369-72cjogxz 2749 4 block block NN cord-015369-72cjogxz 2749 5 ( ( -LRB- cord-015369-72cjogxz 2749 6 ETSB ETSB NNP cord-015369-72cjogxz 2749 7 ) ) -RRB- cord-015369-72cjogxz 2749 8 provides provide VBZ cord-015369-72cjogxz 2749 9 excellent excellent JJ cord-015369-72cjogxz 2749 10 outcome outcome NN cord-015369-72cjogxz 2749 11 for for IN cord-015369-72cjogxz 2749 12 palmo palmo JJ cord-015369-72cjogxz 2749 13 - - HYPH cord-015369-72cjogxz 2749 14 axillary axillary JJ cord-015369-72cjogxz 2749 15 hyperhidrosis hyperhidrosis NN cord-015369-72cjogxz 2749 16 ( ( -LRB- cord-015369-72cjogxz 2749 17 HH HH NNP cord-015369-72cjogxz 2749 18 ) ) -RRB- cord-015369-72cjogxz 2749 19 . . . cord-015369-72cjogxz 2750 1 The the DT cord-015369-72cjogxz 2750 2 aim aim NN cord-015369-72cjogxz 2750 3 of of IN cord-015369-72cjogxz 2750 4 the the DT cord-015369-72cjogxz 2750 5 study study NN cord-015369-72cjogxz 2750 6 was be VBD cord-015369-72cjogxz 2750 7 to to TO cord-015369-72cjogxz 2750 8 investigate investigate VB cord-015369-72cjogxz 2750 9 the the DT cord-015369-72cjogxz 2750 10 long long JJ cord-015369-72cjogxz 2750 11 term term NN cord-015369-72cjogxz 2750 12 effects effect NNS cord-015369-72cjogxz 2750 13 of of IN cord-015369-72cjogxz 2750 14 ETSB4 ETSB4 NNS cord-015369-72cjogxz 2750 15 . . . cord-015369-72cjogxz 2751 1 Methods method NNS cord-015369-72cjogxz 2751 2 . . . cord-015369-72cjogxz 2752 1 Between between IN cord-015369-72cjogxz 2752 2 2002 2002 CD cord-015369-72cjogxz 2752 3 and and CC cord-015369-72cjogxz 2752 4 2009 2009 CD cord-015369-72cjogxz 2752 5 184 184 CD cord-015369-72cjogxz 2752 6 patients patient NNS cord-015369-72cjogxz 2752 7 ( ( -LRB- cord-015369-72cjogxz 2752 8 mean mean VB cord-015369-72cjogxz 2752 9 age age NN cord-015369-72cjogxz 2752 10 30 30 CD cord-015369-72cjogxz 2752 11 AE AE NNP cord-015369-72cjogxz 2752 12 10 10 CD cord-015369-72cjogxz 2752 13 years year NNS cord-015369-72cjogxz 2752 14 ) ) -RRB- cord-015369-72cjogxz 2752 15 underwent undergo VBD cord-015369-72cjogxz 2752 16 367 367 CD cord-015369-72cjogxz 2752 17 ETSB4 ETSB4 NNS cord-015369-72cjogxz 2752 18 procedures procedure NNS cord-015369-72cjogxz 2752 19 in in IN cord-015369-72cjogxz 2752 20 a a DT cord-015369-72cjogxz 2752 21 prospective prospective JJ cord-015369-72cjogxz 2752 22 study study NN cord-015369-72cjogxz 2752 23 . . . cord-015369-72cjogxz 2753 1 Satisfaction satisfaction NN cord-015369-72cjogxz 2753 2 rates rate NNS cord-015369-72cjogxz 2753 3 and and CC cord-015369-72cjogxz 2753 4 two two CD cord-015369-72cjogxz 2753 5 validated validate VBN cord-015369-72cjogxz 2753 6 Quality quality NN cord-015369-72cjogxz 2753 7 of of IN cord-015369-72cjogxz 2753 8 life life NN cord-015369-72cjogxz 2753 9 ( ( -LRB- cord-015369-72cjogxz 2753 10 Qol qol NN cord-015369-72cjogxz 2753 11 ) ) -RRB- cord-015369-72cjogxz 2753 12 questionnaires questionnaire NNS cord-015369-72cjogxz 2753 13 were be VBD cord-015369-72cjogxz 2753 14 assessing assess VBG cord-015369-72cjogxz 2753 15 postoperative postoperative JJ cord-015369-72cjogxz 2753 16 outcome outcome NN cord-015369-72cjogxz 2753 17 ( ( -LRB- cord-015369-72cjogxz 2753 18 Keller Keller NNP cord-015369-72cjogxz 2753 19 : : : cord-015369-72cjogxz 2753 20 0 0 CD cord-015369-72cjogxz 2753 21 - - SYM cord-015369-72cjogxz 2753 22 10 10 CD cord-015369-72cjogxz 2753 23 and and CC cord-015369-72cjogxz 2753 24 Milanez Milanez NNP cord-015369-72cjogxz 2753 25 de de NNP cord-015369-72cjogxz 2753 26 Campos Campos NNP cord-015369-72cjogxz 2753 27 : : : cord-015369-72cjogxz 2753 28 1 1 CD cord-015369-72cjogxz 2753 29 - - SYM cord-015369-72cjogxz 2753 30 5 5 CD cord-015369-72cjogxz 2753 31 ; ; SYM cord-015369-72cjogxz 2753 32 0 0 CD cord-015369-72cjogxz 2753 33 : : : cord-015369-72cjogxz 2754 1 no no DT cord-015369-72cjogxz 2754 2 symptoms symptom NNS cord-015369-72cjogxz 2754 3 ; ; : cord-015369-72cjogxz 2754 4 5 5 CD cord-015369-72cjogxz 2754 5 or or CC cord-015369-72cjogxz 2754 6 10 10 CD cord-015369-72cjogxz 2754 7 : : : cord-015369-72cjogxz 2754 8 maximal maximal JJ cord-015369-72cjogxz 2754 9 symptoms symptom NNS cord-015369-72cjogxz 2754 10 ) ) -RRB- cord-015369-72cjogxz 2754 11 , , , cord-015369-72cjogxz 2754 12 respectively respectively RB cord-015369-72cjogxz 2754 13 . . . cord-015369-72cjogxz 2755 1 Mean mean VB cord-015369-72cjogxz 2755 2 follow follow VB cord-015369-72cjogxz 2755 3 up up RP cord-015369-72cjogxz 2755 4 was be VBD cord-015369-72cjogxz 2755 5 48.3 48.3 CD cord-015369-72cjogxz 2755 6 AE AE NNP cord-015369-72cjogxz 2755 7 25.2 25.2 CD cord-015369-72cjogxz 2755 8 months month NNS cord-015369-72cjogxz 2755 9 . . . cord-015369-72cjogxz 2756 1 Results result NNS cord-015369-72cjogxz 2756 2 . . . cord-015369-72cjogxz 2757 1 One one CD cord-015369-72cjogxz 2757 2 hundred hundred CD cord-015369-72cjogxz 2757 3 and and CC cord-015369-72cjogxz 2757 4 sixty sixty CD cord-015369-72cjogxz 2757 5 - - HYPH cord-015369-72cjogxz 2757 6 two two CD cord-015369-72cjogxz 2757 7 patients patient NNS cord-015369-72cjogxz 2757 8 ( ( -LRB- cord-015369-72cjogxz 2757 9 88.0 88.0 CD cord-015369-72cjogxz 2757 10 % % NN cord-015369-72cjogxz 2757 11 ) ) -RRB- cord-015369-72cjogxz 2757 12 had have VBD cord-015369-72cjogxz 2757 13 palmar palmar NN cord-015369-72cjogxz 2757 14 and and CC cord-015369-72cjogxz 2757 15 137 137 CD cord-015369-72cjogxz 2757 16 patients patient NNS cord-015369-72cjogxz 2757 17 ( ( -LRB- cord-015369-72cjogxz 2757 18 74.5 74.5 CD cord-015369-72cjogxz 2757 19 % % NN cord-015369-72cjogxz 2757 20 ) ) -RRB- cord-015369-72cjogxz 2757 21 axillary axillary JJ cord-015369-72cjogxz 2757 22 HH hh NN cord-015369-72cjogxz 2757 23 . . . cord-015369-72cjogxz 2758 1 All all DT cord-015369-72cjogxz 2758 2 patients patient NNS cord-015369-72cjogxz 2758 3 with with IN cord-015369-72cjogxz 2758 4 palmar palmar NN cord-015369-72cjogxz 2758 5 HH hh NN cord-015369-72cjogxz 2758 6 were be VBD cord-015369-72cjogxz 2758 7 completely completely RB cord-015369-72cjogxz 2758 8 or or CC cord-015369-72cjogxz 2758 9 almost almost RB cord-015369-72cjogxz 2758 10 dry dry JJ cord-015369-72cjogxz 2758 11 postoperatively postoperatively RB cord-015369-72cjogxz 2758 12 whereas whereas IN cord-015369-72cjogxz 2758 13 1 1 CD cord-015369-72cjogxz 2758 14 patient patient NN cord-015369-72cjogxz 2758 15 ( ( -LRB- cord-015369-72cjogxz 2758 16 0.5 0.5 CD cord-015369-72cjogxz 2758 17 % % NN cord-015369-72cjogxz 2758 18 ) ) -RRB- cord-015369-72cjogxz 2758 19 developed develop VBN cord-015369-72cjogxz 2758 20 recurrence recurrence NN cord-015369-72cjogxz 2758 21 of of IN cord-015369-72cjogxz 2758 22 the the DT cord-015369-72cjogxz 2758 23 primary primary JJ cord-015369-72cjogxz 2758 24 disease disease NN cord-015369-72cjogxz 2758 25 at at TO cord-015369-72cjogxz 2758 26 follow follow VB cord-015369-72cjogxz 2758 27 up up RP cord-015369-72cjogxz 2758 28 . . . cord-015369-72cjogxz 2759 1 Among among IN cord-015369-72cjogxz 2759 2 patients patient NNS cord-015369-72cjogxz 2759 3 with with IN cord-015369-72cjogxz 2759 4 axillary axillary JJ cord-015369-72cjogxz 2759 5 HH hh NN cord-015369-72cjogxz 2759 6 , , , cord-015369-72cjogxz 2759 7 recurrences recurrence NNS cord-015369-72cjogxz 2759 8 appeared appear VBD cord-015369-72cjogxz 2759 9 in in IN cord-015369-72cjogxz 2759 10 3.5 3.5 CD cord-015369-72cjogxz 2759 11 % % NN cord-015369-72cjogxz 2759 12 within within IN cord-015369-72cjogxz 2759 13 six six CD cord-015369-72cjogxz 2759 14 weeks week NNS cord-015369-72cjogxz 2759 15 and and CC cord-015369-72cjogxz 2759 16 rose rise VBD cord-015369-72cjogxz 2759 17 up up RP cord-015369-72cjogxz 2759 18 to to IN cord-015369-72cjogxz 2759 19 6.3 6.3 CD cord-015369-72cjogxz 2759 20 % % NN cord-015369-72cjogxz 2759 21 at at IN cord-015369-72cjogxz 2759 22 follow follow NN cord-015369-72cjogxz 2759 23 up up RP cord-015369-72cjogxz 2759 24 . . . cord-015369-72cjogxz 2760 1 Compensatory compensatory JJ cord-015369-72cjogxz 2760 2 sweating sweating NN cord-015369-72cjogxz 2760 3 ( ( -LRB- cord-015369-72cjogxz 2760 4 CS CS NNP cord-015369-72cjogxz 2760 5 ) ) -RRB- cord-015369-72cjogxz 2760 6 and and CC cord-015369-72cjogxz 2760 7 gustatory gustatory JJ cord-015369-72cjogxz 2760 8 sweating sweating NN cord-015369-72cjogxz 2760 9 were be VBD cord-015369-72cjogxz 2760 10 observed observe VBN cord-015369-72cjogxz 2760 11 in in IN cord-015369-72cjogxz 2760 12 16 16 CD cord-015369-72cjogxz 2760 13 . . . cord-015369-72cjogxz 2761 1 8 8 CD cord-015369-72cjogxz 2761 2 % % NN cord-015369-72cjogxz 2761 3 Background background NN cord-015369-72cjogxz 2761 4 . . . cord-015369-72cjogxz 2762 1 At at IN cord-015369-72cjogxz 2762 2 the the DT cord-015369-72cjogxz 2762 3 time time NN cord-015369-72cjogxz 2762 4 when when WRB cord-015369-72cjogxz 2762 5 NOTES note NNS cord-015369-72cjogxz 2762 6 techniques technique NNS cord-015369-72cjogxz 2762 7 struggle struggle VBP cord-015369-72cjogxz 2762 8 on on IN cord-015369-72cjogxz 2762 9 diverse diverse JJ cord-015369-72cjogxz 2762 10 problems problem NNS cord-015369-72cjogxz 2762 11 a a DT cord-015369-72cjogxz 2762 12 novel novel JJ cord-015369-72cjogxz 2762 13 single single JJ cord-015369-72cjogxz 2762 14 incision incision NN cord-015369-72cjogxz 2762 15 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2762 16 method method NN cord-015369-72cjogxz 2762 17 is be VBZ cord-015369-72cjogxz 2762 18 developed develop VBN cord-015369-72cjogxz 2762 19 utilizing utilize VBG cord-015369-72cjogxz 2762 20 the the DT cord-015369-72cjogxz 2762 21 umbilicus umbilicus NN cord-015369-72cjogxz 2762 22 as as IN cord-015369-72cjogxz 2762 23 embryonic embryonic JJ cord-015369-72cjogxz 2762 24 natural natural JJ cord-015369-72cjogxz 2762 25 orifice orifice NN cord-015369-72cjogxz 2762 26 . . . cord-015369-72cjogxz 2763 1 Three three CD cord-015369-72cjogxz 2763 2 intra intra JJ cord-015369-72cjogxz 2763 3 - - JJ cord-015369-72cjogxz 2763 4 umbilical umbilical JJ cord-015369-72cjogxz 2763 5 trocars trocar NNS cord-015369-72cjogxz 2763 6 allow allow VBP cord-015369-72cjogxz 2763 7 a a DT cord-015369-72cjogxz 2763 8 minimal minimal JJ cord-015369-72cjogxz 2763 9 invasive invasive JJ cord-015369-72cjogxz 2763 10 procedure procedure NN cord-015369-72cjogxz 2763 11 which which WDT cord-015369-72cjogxz 2763 12 results result VBZ cord-015369-72cjogxz 2763 13 in in IN cord-015369-72cjogxz 2763 14 a a DT cord-015369-72cjogxz 2763 15 non non JJ cord-015369-72cjogxz 2763 16 - - JJ cord-015369-72cjogxz 2763 17 visible visible JJ cord-015369-72cjogxz 2763 18 postoperative postoperative JJ cord-015369-72cjogxz 2763 19 scar scar NN cord-015369-72cjogxz 2763 20 . . . cord-015369-72cjogxz 2764 1 Methods method NNS cord-015369-72cjogxz 2764 2 . . . cord-015369-72cjogxz 2765 1 Twenty twenty CD cord-015369-72cjogxz 2765 2 - - HYPH cord-015369-72cjogxz 2765 3 four four CD cord-015369-72cjogxz 2765 4 patients patient NNS cord-015369-72cjogxz 2765 5 ( ( -LRB- cord-015369-72cjogxz 2765 6 age age NN cord-015369-72cjogxz 2765 7 : : : cord-015369-72cjogxz 2765 8 24 24 CD cord-015369-72cjogxz 2765 9 - - HYPH cord-015369-72cjogxz 2765 10 86a 86a NNS cord-015369-72cjogxz 2765 11 ) ) -RRB- cord-015369-72cjogxz 2765 12 underwent undergo VBD cord-015369-72cjogxz 2765 13 single single JJ cord-015369-72cjogxz 2765 14 incision incision NN cord-015369-72cjogxz 2765 15 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2765 16 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 2765 17 ( ( -LRB- cord-015369-72cjogxz 2765 18 10/08 10/08 CD cord-015369-72cjogxz 2765 19 - - SYM cord-015369-72cjogxz 2765 20 01/09 01/09 CD cord-015369-72cjogxz 2765 21 ) ) -RRB- cord-015369-72cjogxz 2765 22 for for IN cord-015369-72cjogxz 2765 23 gallbladder gallbladder NN cord-015369-72cjogxz 2765 24 stones stone NNS cord-015369-72cjogxz 2765 25 and/or and/or CC cord-015369-72cjogxz 2765 26 cholecystitis cholecystitis NN cord-015369-72cjogxz 2765 27 . . . cord-015369-72cjogxz 2766 1 The the DT cord-015369-72cjogxz 2766 2 entire entire JJ cord-015369-72cjogxz 2766 3 operation operation NN cord-015369-72cjogxz 2766 4 was be VBD cord-015369-72cjogxz 2766 5 carried carry VBN cord-015369-72cjogxz 2766 6 out out RP cord-015369-72cjogxz 2766 7 transumbilically transumbilically RB cord-015369-72cjogxz 2766 8 following follow VBG cord-015369-72cjogxz 2766 9 the the DT cord-015369-72cjogxz 2766 10 standardized standardized JJ cord-015369-72cjogxz 2766 11 principles principle NNS cord-015369-72cjogxz 2766 12 of of IN cord-015369-72cjogxz 2766 13 the the DT cord-015369-72cjogxz 2766 14 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2766 15 technique technique NN cord-015369-72cjogxz 2766 16 . . . cord-015369-72cjogxz 2767 1 One one CD cord-015369-72cjogxz 2767 2 or or CC cord-015369-72cjogxz 2767 3 two two CD cord-015369-72cjogxz 2767 4 ( ( -LRB- cord-015369-72cjogxz 2767 5 in in IN cord-015369-72cjogxz 2767 6 the the DT cord-015369-72cjogxz 2767 7 initial initial JJ cord-015369-72cjogxz 2767 8 5 5 CD cord-015369-72cjogxz 2767 9 patients patient NNS cord-015369-72cjogxz 2767 10 ) ) -RRB- cord-015369-72cjogxz 2767 11 intraperitoneal intraperitoneal JJ cord-015369-72cjogxz 2767 12 suspension suspension NN cord-015369-72cjogxz 2767 13 sutures suture NNS cord-015369-72cjogxz 2767 14 helped help VBD cord-015369-72cjogxz 2767 15 to to TO cord-015369-72cjogxz 2767 16 expose expose VB cord-015369-72cjogxz 2767 17 the the DT cord-015369-72cjogxz 2767 18 anatomical anatomical JJ cord-015369-72cjogxz 2767 19 structures structure NNS cord-015369-72cjogxz 2767 20 . . . cord-015369-72cjogxz 2768 1 Results result NNS cord-015369-72cjogxz 2768 2 . . . cord-015369-72cjogxz 2769 1 In in IN cord-015369-72cjogxz 2769 2 all all DT cord-015369-72cjogxz 2769 3 but but IN cord-015369-72cjogxz 2769 4 two two CD cord-015369-72cjogxz 2769 5 patients patient NNS cord-015369-72cjogxz 2769 6 single single JJ cord-015369-72cjogxz 2769 7 incision incision NN cord-015369-72cjogxz 2769 8 transumbilical transumbilical JJ cord-015369-72cjogxz 2769 9 surgery surgery NN cord-015369-72cjogxz 2769 10 could could MD cord-015369-72cjogxz 2769 11 be be VB cord-015369-72cjogxz 2769 12 completed complete VBN cord-015369-72cjogxz 2769 13 . . . cord-015369-72cjogxz 2770 1 In in IN cord-015369-72cjogxz 2770 2 both both DT cord-015369-72cjogxz 2770 3 cases case NNS cord-015369-72cjogxz 2770 4 placement placement NN cord-015369-72cjogxz 2770 5 of of IN cord-015369-72cjogxz 2770 6 one one CD cord-015369-72cjogxz 2770 7 and and CC cord-015369-72cjogxz 2770 8 two two CD cord-015369-72cjogxz 2770 9 additional additional JJ cord-015369-72cjogxz 2770 10 trocars trocar NNS cord-015369-72cjogxz 2770 11 , , , cord-015369-72cjogxz 2770 12 respectively respectively RB cord-015369-72cjogxz 2770 13 , , , cord-015369-72cjogxz 2770 14 was be VBD cord-015369-72cjogxz 2770 15 necessary necessary JJ cord-015369-72cjogxz 2770 16 due due IN cord-015369-72cjogxz 2770 17 to to IN cord-015369-72cjogxz 2770 18 severe severe JJ cord-015369-72cjogxz 2770 19 adhesions adhesion NNS cord-015369-72cjogxz 2770 20 from from IN cord-015369-72cjogxz 2770 21 previous previous JJ cord-015369-72cjogxz 2770 22 surgery surgery NN cord-015369-72cjogxz 2770 23 . . . cord-015369-72cjogxz 2771 1 The the DT cord-015369-72cjogxz 2771 2 operative operative JJ cord-015369-72cjogxz 2771 3 time time NN cord-015369-72cjogxz 2771 4 was be VBD cord-015369-72cjogxz 2771 5 in in IN cord-015369-72cjogxz 2771 6 Median Median NNP cord-015369-72cjogxz 2771 7 60 60 CD cord-015369-72cjogxz 2772 1 ( ( -LRB- cord-015369-72cjogxz 2772 2 Range Range NNP cord-015369-72cjogxz 2772 3 37 37 CD cord-015369-72cjogxz 2772 4 - - SYM cord-015369-72cjogxz 2772 5 130 130 CD cord-015369-72cjogxz 2772 6 ) ) -RRB- cord-015369-72cjogxz 2772 7 min min NN cord-015369-72cjogxz 2772 8 . . . cord-015369-72cjogxz 2773 1 No no DT cord-015369-72cjogxz 2773 2 intraoperative intraoperative JJ cord-015369-72cjogxz 2773 3 adverse adverse JJ cord-015369-72cjogxz 2773 4 events event NNS cord-015369-72cjogxz 2773 5 were be VBD cord-015369-72cjogxz 2773 6 noticed notice VBN cord-015369-72cjogxz 2773 7 . . . cord-015369-72cjogxz 2774 1 Estimated estimate VBN cord-015369-72cjogxz 2774 2 blood blood NN cord-015369-72cjogxz 2774 3 loss loss NN cord-015369-72cjogxz 2774 4 yielded yield VBD cord-015369-72cjogxz 2774 5 minimal minimal JJ cord-015369-72cjogxz 2774 6 in in IN cord-015369-72cjogxz 2774 7 all all DT cord-015369-72cjogxz 2774 8 cases case NNS cord-015369-72cjogxz 2774 9 . . . cord-015369-72cjogxz 2775 1 Cholangiography Cholangiography NNP cord-015369-72cjogxz 2775 2 was be VBD cord-015369-72cjogxz 2775 3 successfully successfully RB cord-015369-72cjogxz 2775 4 carried carry VBN cord-015369-72cjogxz 2775 5 out out RP cord-015369-72cjogxz 2775 6 in in IN cord-015369-72cjogxz 2775 7 two two CD cord-015369-72cjogxz 2775 8 patients patient NNS cord-015369-72cjogxz 2775 9 . . . cord-015369-72cjogxz 2776 1 All all DT cord-015369-72cjogxz 2776 2 returned return VBD cord-015369-72cjogxz 2776 3 to to IN cord-015369-72cjogxz 2776 4 oral oral JJ cord-015369-72cjogxz 2776 5 diet diet NN cord-015369-72cjogxz 2776 6 after after IN cord-015369-72cjogxz 2776 7 six six CD cord-015369-72cjogxz 2776 8 hours hour NNS cord-015369-72cjogxz 2776 9 . . . cord-015369-72cjogxz 2777 1 They -PRON- PRP cord-015369-72cjogxz 2777 2 were be VBD cord-015369-72cjogxz 2777 3 discharged discharge VBN cord-015369-72cjogxz 2777 4 in in IN cord-015369-72cjogxz 2777 5 Median Median NNP cord-015369-72cjogxz 2777 6 on on IN cord-015369-72cjogxz 2777 7 postoperative postoperative JJ cord-015369-72cjogxz 2777 8 day day NN cord-015369-72cjogxz 2777 9 3 3 CD cord-015369-72cjogxz 2777 10 in in IN cord-015369-72cjogxz 2777 11 accordance accordance NN cord-015369-72cjogxz 2777 12 with with IN cord-015369-72cjogxz 2777 13 local local JJ cord-015369-72cjogxz 2777 14 custom custom NN cord-015369-72cjogxz 2777 15 . . . cord-015369-72cjogxz 2778 1 An an DT cord-015369-72cjogxz 2778 2 optimal optimal JJ cord-015369-72cjogxz 2778 3 postoperative postoperative JJ cord-015369-72cjogxz 2778 4 and and CC cord-015369-72cjogxz 2778 5 cosmetic cosmetic JJ cord-015369-72cjogxz 2778 6 result result NN cord-015369-72cjogxz 2778 7 without without IN cord-015369-72cjogxz 2778 8 apparent apparent JJ cord-015369-72cjogxz 2778 9 scar scar NN cord-015369-72cjogxz 2778 10 was be VBD cord-015369-72cjogxz 2778 11 documented document VBN cord-015369-72cjogxz 2778 12 at at IN cord-015369-72cjogxz 2778 13 follow follow NN cord-015369-72cjogxz 2778 14 - - HYPH cord-015369-72cjogxz 2778 15 up up NN cord-015369-72cjogxz 2778 16 . . . cord-015369-72cjogxz 2779 1 Conclusions conclusion NNS cord-015369-72cjogxz 2779 2 . . . cord-015369-72cjogxz 2780 1 This this DT cord-015369-72cjogxz 2780 2 initial initial JJ cord-015369-72cjogxz 2780 3 series series NN cord-015369-72cjogxz 2780 4 presents present VBZ cord-015369-72cjogxz 2780 5 for for IN cord-015369-72cjogxz 2780 6 the the DT cord-015369-72cjogxz 2780 7 first first JJ cord-015369-72cjogxz 2780 8 time time NN cord-015369-72cjogxz 2780 9 a a DT cord-015369-72cjogxz 2780 10 novel novel JJ cord-015369-72cjogxz 2780 11 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2780 12 technique technique NN cord-015369-72cjogxz 2780 13 for for IN cord-015369-72cjogxz 2780 14 E e NN cord-015369-72cjogxz 2780 15 - - NN cord-015369-72cjogxz 2780 16 NOTES note NNS cord-015369-72cjogxz 2780 17 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 2780 18 utilizing utilize VBG cord-015369-72cjogxz 2780 19 a a DT cord-015369-72cjogxz 2780 20 single single JJ cord-015369-72cjogxz 2780 21 ' ' '' cord-015369-72cjogxz 2780 22 ' ' '' cord-015369-72cjogxz 2780 23 scar scar NN cord-015369-72cjogxz 2780 24 - - HYPH cord-015369-72cjogxz 2780 25 less less NN cord-015369-72cjogxz 2780 26 ' ' '' cord-015369-72cjogxz 2780 27 ' ' '' cord-015369-72cjogxz 2780 28 intraumbilical intraumbilical NNP cord-015369-72cjogxz 2780 29 approach approach NN cord-015369-72cjogxz 2780 30 which which WDT cord-015369-72cjogxz 2780 31 minimizes minimize VBZ cord-015369-72cjogxz 2780 32 the the DT cord-015369-72cjogxz 2780 33 surgical surgical JJ cord-015369-72cjogxz 2780 34 trauma trauma NN cord-015369-72cjogxz 2780 35 . . . cord-015369-72cjogxz 2781 1 Background background NN cord-015369-72cjogxz 2781 2 . . . cord-015369-72cjogxz 2782 1 During during IN cord-015369-72cjogxz 2782 2 the the DT cord-015369-72cjogxz 2782 3 past past JJ cord-015369-72cjogxz 2782 4 decades decade NNS cord-015369-72cjogxz 2782 5 anecdotic anecdotic JJ cord-015369-72cjogxz 2782 6 reports report NNS cord-015369-72cjogxz 2782 7 on on IN cord-015369-72cjogxz 2782 8 single single JJ cord-015369-72cjogxz 2782 9 incision incision NN cord-015369-72cjogxz 2782 10 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2782 11 appendectomy appendectomy NN cord-015369-72cjogxz 2782 12 were be VBD cord-015369-72cjogxz 2782 13 published publish VBN cord-015369-72cjogxz 2782 14 . . . cord-015369-72cjogxz 2783 1 The the DT cord-015369-72cjogxz 2783 2 scientific scientific JJ cord-015369-72cjogxz 2783 3 interest interest NN cord-015369-72cjogxz 2783 4 in in IN cord-015369-72cjogxz 2783 5 NOTES note NNS cord-015369-72cjogxz 2783 6 procedures procedure NNS cord-015369-72cjogxz 2783 7 led lead VBD cord-015369-72cjogxz 2783 8 to to IN cord-015369-72cjogxz 2783 9 a a DT cord-015369-72cjogxz 2783 10 renaissance renaissance NN cord-015369-72cjogxz 2783 11 of of IN cord-015369-72cjogxz 2783 12 this this DT cord-015369-72cjogxz 2783 13 technique technique NN cord-015369-72cjogxz 2783 14 in in IN cord-015369-72cjogxz 2783 15 the the DT cord-015369-72cjogxz 2783 16 surge surge NN cord-015369-72cjogxz 2783 17 for for IN cord-015369-72cjogxz 2783 18 a a DT cord-015369-72cjogxz 2783 19 minimal minimal JJ cord-015369-72cjogxz 2783 20 invasive invasive JJ cord-015369-72cjogxz 2783 21 approach approach NN cord-015369-72cjogxz 2783 22 . . . cord-015369-72cjogxz 2784 1 We -PRON- PRP cord-015369-72cjogxz 2784 2 developed develop VBD cord-015369-72cjogxz 2784 3 a a DT cord-015369-72cjogxz 2784 4 novel novel JJ cord-015369-72cjogxz 2784 5 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2784 6 transumbilical transumbilical JJ cord-015369-72cjogxz 2784 7 method method NN cord-015369-72cjogxz 2784 8 utilizing utilize VBG cord-015369-72cjogxz 2784 9 three three CD cord-015369-72cjogxz 2784 10 instruments instrument NNS cord-015369-72cjogxz 2784 11 exclusively exclusively RB cord-015369-72cjogxz 2784 12 through through IN cord-015369-72cjogxz 2784 13 the the DT cord-015369-72cjogxz 2784 14 embryonic embryonic NNP cord-015369-72cjogxz 2784 15 ' ' POS cord-015369-72cjogxz 2784 16 ' ' '' cord-015369-72cjogxz 2784 17 non non JJ cord-015369-72cjogxz 2784 18 - - JJ cord-015369-72cjogxz 2784 19 visible visible JJ cord-015369-72cjogxz 2784 20 ' ' '' cord-015369-72cjogxz 2784 21 ' ' '' cord-015369-72cjogxz 2784 22 scar scar NN cord-015369-72cjogxz 2784 23 . . . cord-015369-72cjogxz 2785 1 Methods method NNS cord-015369-72cjogxz 2785 2 . . . cord-015369-72cjogxz 2786 1 Two two CD cord-015369-72cjogxz 2786 2 patients patient NNS cord-015369-72cjogxz 2786 3 ( ( -LRB- cord-015369-72cjogxz 2786 4 both both DT cord-015369-72cjogxz 2786 5 28a 28a NNS cord-015369-72cjogxz 2786 6 ) ) -RRB- cord-015369-72cjogxz 2786 7 underwent undergo VBD cord-015369-72cjogxz 2786 8 single single JJ cord-015369-72cjogxz 2786 9 incision incision NN cord-015369-72cjogxz 2787 1 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2787 2 appendectomy appendectomy NN cord-015369-72cjogxz 2787 3 ( ( -LRB- cord-015369-72cjogxz 2787 4 11/08 11/08 CD cord-015369-72cjogxz 2787 5 - - SYM cord-015369-72cjogxz 2787 6 12/08 12/08 CD cord-015369-72cjogxz 2787 7 ) ) -RRB- cord-015369-72cjogxz 2787 8 . . . cord-015369-72cjogxz 2788 1 The the DT cord-015369-72cjogxz 2788 2 entire entire JJ cord-015369-72cjogxz 2788 3 operation operation NN cord-015369-72cjogxz 2788 4 was be VBD cord-015369-72cjogxz 2788 5 carried carry VBN cord-015369-72cjogxz 2788 6 out out RP cord-015369-72cjogxz 2788 7 transumbilically transumbilically RB cord-015369-72cjogxz 2788 8 following follow VBG cord-015369-72cjogxz 2788 9 the the DT cord-015369-72cjogxz 2788 10 standardized standardized JJ cord-015369-72cjogxz 2788 11 principles principle NNS cord-015369-72cjogxz 2788 12 of of IN cord-015369-72cjogxz 2788 13 the the DT cord-015369-72cjogxz 2788 14 minimal minimal JJ cord-015369-72cjogxz 2788 15 invasive invasive JJ cord-015369-72cjogxz 2788 16 appendectomy appendectomy NN cord-015369-72cjogxz 2788 17 technique technique NN cord-015369-72cjogxz 2788 18 . . . cord-015369-72cjogxz 2789 1 Results result NNS cord-015369-72cjogxz 2789 2 . . . cord-015369-72cjogxz 2790 1 Both both DT cord-015369-72cjogxz 2790 2 patients patient NNS cord-015369-72cjogxz 2790 3 underwent undergo VBD cord-015369-72cjogxz 2790 4 surgery surgery NN cord-015369-72cjogxz 2790 5 for for IN cord-015369-72cjogxz 2790 6 acute acute JJ cord-015369-72cjogxz 2790 7 appendicitis appendicitis NN cord-015369-72cjogxz 2790 8 with with IN cord-015369-72cjogxz 2790 9 perifocal perifocal JJ cord-015369-72cjogxz 2790 10 peritonitis peritonitis NN cord-015369-72cjogxz 2790 11 . . . cord-015369-72cjogxz 2791 1 After after IN cord-015369-72cjogxz 2791 2 dissection dissection NN cord-015369-72cjogxz 2791 3 of of IN cord-015369-72cjogxz 2791 4 the the DT cord-015369-72cjogxz 2791 5 appendicular appendicular JJ cord-015369-72cjogxz 2791 6 artery artery NN cord-015369-72cjogxz 2791 7 the the DT cord-015369-72cjogxz 2791 8 appendix appendix NN cord-015369-72cjogxz 2791 9 was be VBD cord-015369-72cjogxz 2791 10 transected transect VBN cord-015369-72cjogxz 2791 11 by by IN cord-015369-72cjogxz 2791 12 use use NN cord-015369-72cjogxz 2791 13 of of IN cord-015369-72cjogxz 2791 14 a a DT cord-015369-72cjogxz 2791 15 loop loop NN cord-015369-72cjogxz 2791 16 and and CC cord-015369-72cjogxz 2791 17 a a DT cord-015369-72cjogxz 2791 18 stapler stapler NN cord-015369-72cjogxz 2791 19 , , , cord-015369-72cjogxz 2791 20 respectively respectively RB cord-015369-72cjogxz 2791 21 . . . cord-015369-72cjogxz 2792 1 The the DT cord-015369-72cjogxz 2792 2 operative operative JJ cord-015369-72cjogxz 2792 3 time time NN cord-015369-72cjogxz 2792 4 was be VBD cord-015369-72cjogxz 2792 5 77 77 CD cord-015369-72cjogxz 2792 6 min min NN cord-015369-72cjogxz 2792 7 and and CC cord-015369-72cjogxz 2792 8 67 67 CD cord-015369-72cjogxz 2792 9 min min NN cord-015369-72cjogxz 2792 10 . . . cord-015369-72cjogxz 2793 1 No no DT cord-015369-72cjogxz 2793 2 additional additional JJ cord-015369-72cjogxz 2793 3 trocar trocar NN cord-015369-72cjogxz 2793 4 had have VBD cord-015369-72cjogxz 2793 5 to to TO cord-015369-72cjogxz 2793 6 be be VB cord-015369-72cjogxz 2793 7 placed place VBN cord-015369-72cjogxz 2793 8 . . . cord-015369-72cjogxz 2794 1 No no DT cord-015369-72cjogxz 2794 2 intraoperative intraoperative JJ cord-015369-72cjogxz 2794 3 adverse adverse JJ cord-015369-72cjogxz 2794 4 events event NNS cord-015369-72cjogxz 2794 5 or or CC cord-015369-72cjogxz 2794 6 significant significant JJ cord-015369-72cjogxz 2794 7 perioperative perioperative JJ cord-015369-72cjogxz 2794 8 complication complication NN cord-015369-72cjogxz 2794 9 was be VBD cord-015369-72cjogxz 2794 10 noticed notice VBN cord-015369-72cjogxz 2794 11 . . . cord-015369-72cjogxz 2795 1 Estimated estimate VBN cord-015369-72cjogxz 2795 2 blood blood NN cord-015369-72cjogxz 2795 3 loss loss NN cord-015369-72cjogxz 2795 4 yielded yield VBD cord-015369-72cjogxz 2795 5 minimal minimal JJ cord-015369-72cjogxz 2795 6 in in IN cord-015369-72cjogxz 2795 7 both both DT cord-015369-72cjogxz 2795 8 cases case NNS cord-015369-72cjogxz 2795 9 . . . cord-015369-72cjogxz 2796 1 One one CD cord-015369-72cjogxz 2796 2 patient patient NN cord-015369-72cjogxz 2796 3 suffered suffer VBD cord-015369-72cjogxz 2796 4 from from IN cord-015369-72cjogxz 2796 5 infectious infectious JJ cord-015369-72cjogxz 2796 6 enteritis enteritis NN cord-015369-72cjogxz 2796 7 and and CC cord-015369-72cjogxz 2796 8 mild mild JJ cord-015369-72cjogxz 2796 9 wound wound NN cord-015369-72cjogxz 2796 10 infection infection NN cord-015369-72cjogxz 2796 11 postoperatively postoperatively RB cord-015369-72cjogxz 2796 12 . . . cord-015369-72cjogxz 2797 1 Oral oral JJ cord-015369-72cjogxz 2797 2 diet diet NN cord-015369-72cjogxz 2797 3 was be VBD cord-015369-72cjogxz 2797 4 resumed resume VBN cord-015369-72cjogxz 2797 5 immediately immediately RB cord-015369-72cjogxz 2797 6 after after IN cord-015369-72cjogxz 2797 7 the the DT cord-015369-72cjogxz 2797 8 operation operation NN cord-015369-72cjogxz 2797 9 . . . cord-015369-72cjogxz 2798 1 At at IN cord-015369-72cjogxz 2798 2 follow follow VB cord-015369-72cjogxz 2798 3 - - HYPH cord-015369-72cjogxz 2798 4 up up RP cord-015369-72cjogxz 2798 5 patients patient NNS cord-015369-72cjogxz 2798 6 presented present VBN cord-015369-72cjogxz 2798 7 with with IN cord-015369-72cjogxz 2798 8 an an DT cord-015369-72cjogxz 2798 9 outstanding outstanding JJ cord-015369-72cjogxz 2798 10 cosmetic cosmetic NN cord-015369-72cjogxz 2798 11 result result NN cord-015369-72cjogxz 2798 12 without without IN cord-015369-72cjogxz 2798 13 apparent apparent JJ cord-015369-72cjogxz 2798 14 scarring scarring NN cord-015369-72cjogxz 2798 15 . . . cord-015369-72cjogxz 2799 1 Conclusions conclusion NNS cord-015369-72cjogxz 2799 2 . . . cord-015369-72cjogxz 2800 1 For for IN cord-015369-72cjogxz 2800 2 the the DT cord-015369-72cjogxz 2800 3 first first JJ cord-015369-72cjogxz 2800 4 time time NN cord-015369-72cjogxz 2800 5 instrumental instrumental JJ cord-015369-72cjogxz 2800 6 developments development NNS cord-015369-72cjogxz 2800 7 allow allow VBP cord-015369-72cjogxz 2800 8 a a DT cord-015369-72cjogxz 2800 9 novel novel JJ cord-015369-72cjogxz 2800 10 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2800 11 technique technique NN cord-015369-72cjogxz 2800 12 for for IN cord-015369-72cjogxz 2800 13 appendectomy appendectomy NN cord-015369-72cjogxz 2800 14 utilizing utilize VBG cord-015369-72cjogxz 2800 15 flexible flexible JJ cord-015369-72cjogxz 2800 16 instruments instrument NNS cord-015369-72cjogxz 2800 17 through through IN cord-015369-72cjogxz 2800 18 a a DT cord-015369-72cjogxz 2800 19 single single JJ cord-015369-72cjogxz 2800 20 intraumbilical intraumbilical JJ cord-015369-72cjogxz 2800 21 approach approach NN cord-015369-72cjogxz 2800 22 resulting result VBG cord-015369-72cjogxz 2800 23 in in IN cord-015369-72cjogxz 2800 24 a a DT cord-015369-72cjogxz 2800 25 non non JJ cord-015369-72cjogxz 2800 26 - - JJ cord-015369-72cjogxz 2800 27 visible visible JJ cord-015369-72cjogxz 2800 28 scar scar NN cord-015369-72cjogxz 2800 29 . . . cord-015369-72cjogxz 2801 1 Methods method NNS cord-015369-72cjogxz 2801 2 . . . cord-015369-72cjogxz 2802 1 Twenty twenty CD cord-015369-72cjogxz 2802 2 - - HYPH cord-015369-72cjogxz 2802 3 three three CD cord-015369-72cjogxz 2802 4 patients patient NNS cord-015369-72cjogxz 2802 5 ( ( -LRB- cord-015369-72cjogxz 2802 6 4 4 CD cord-015369-72cjogxz 2802 7 female/19 female/19 NNP cord-015369-72cjogxz 2802 8 male male NN cord-015369-72cjogxz 2802 9 ; ; , cord-015369-72cjogxz 2802 10 age age NN cord-015369-72cjogxz 2802 11 : : : cord-015369-72cjogxz 2802 12 36 36 CD cord-015369-72cjogxz 2802 13 - - HYPH cord-015369-72cjogxz 2802 14 75a 75a NNPS cord-015369-72cjogxz 2802 15 ) ) -RRB- cord-015369-72cjogxz 2802 16 underwent undergo VBD cord-015369-72cjogxz 2802 17 single single JJ cord-015369-72cjogxz 2802 18 incision incision NN cord-015369-72cjogxz 2802 19 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2802 20 inguinal inguinal JJ cord-015369-72cjogxz 2802 21 hernia hernia NN cord-015369-72cjogxz 2802 22 repair repair NN cord-015369-72cjogxz 2802 23 ( ( -LRB- cord-015369-72cjogxz 2802 24 10/08 10/08 CD cord-015369-72cjogxz 2802 25 - - SYM cord-015369-72cjogxz 2802 26 01/09 01/09 CD cord-015369-72cjogxz 2802 27 ) ) -RRB- cord-015369-72cjogxz 2802 28 . . . cord-015369-72cjogxz 2803 1 The the DT cord-015369-72cjogxz 2803 2 entire entire JJ cord-015369-72cjogxz 2803 3 operation operation NN cord-015369-72cjogxz 2803 4 was be VBD cord-015369-72cjogxz 2803 5 carried carry VBN cord-015369-72cjogxz 2803 6 out out RP cord-015369-72cjogxz 2803 7 transumbilically transumbilically RB cord-015369-72cjogxz 2803 8 following follow VBG cord-015369-72cjogxz 2803 9 the the DT cord-015369-72cjogxz 2803 10 standardized standardized JJ cord-015369-72cjogxz 2803 11 principles principle NNS cord-015369-72cjogxz 2803 12 of of IN cord-015369-72cjogxz 2803 13 the the DT cord-015369-72cjogxz 2803 14 TAPP TAPP NNP cord-015369-72cjogxz 2803 15 technique technique NN cord-015369-72cjogxz 2803 16 . . . cord-015369-72cjogxz 2804 1 Results result NNS cord-015369-72cjogxz 2804 2 . . . cord-015369-72cjogxz 2805 1 Sixteen sixteen CD cord-015369-72cjogxz 2805 2 patients patient NNS cord-015369-72cjogxz 2805 3 underwent undergo VBD cord-015369-72cjogxz 2805 4 single single JJ cord-015369-72cjogxz 2805 5 site site NN cord-015369-72cjogxz 2805 6 surgery surgery NN cord-015369-72cjogxz 2805 7 ( ( -LRB- cord-015369-72cjogxz 2805 8 15 15 CD cord-015369-72cjogxz 2805 9 primary/1 primary/1 NN cord-015369-72cjogxz 2805 10 recurrence recurrence NN cord-015369-72cjogxz 2805 11 procedures procedure NNS cord-015369-72cjogxz 2805 12 ) ) -RRB- cord-015369-72cjogxz 2805 13 , , , cord-015369-72cjogxz 2805 14 whereas whereas IN cord-015369-72cjogxz 2805 15 bilateral bilateral JJ cord-015369-72cjogxz 2805 16 hernia hernia NN cord-015369-72cjogxz 2805 17 repair repair NN cord-015369-72cjogxz 2805 18 was be VBD cord-015369-72cjogxz 2805 19 necessary necessary JJ cord-015369-72cjogxz 2805 20 in in IN cord-015369-72cjogxz 2805 21 seven seven CD cord-015369-72cjogxz 2805 22 patients patient NNS cord-015369-72cjogxz 2805 23 . . . cord-015369-72cjogxz 2806 1 The the DT cord-015369-72cjogxz 2806 2 operative operative JJ cord-015369-72cjogxz 2806 3 time time NN cord-015369-72cjogxz 2806 4 was be VBD cord-015369-72cjogxz 2806 5 39 39 CD cord-015369-72cjogxz 2806 6 - - SYM cord-015369-72cjogxz 2806 7 125 125 CD cord-015369-72cjogxz 2806 8 min min NN cord-015369-72cjogxz 2806 9 and and CC cord-015369-72cjogxz 2806 10 48 48 CD cord-015369-72cjogxz 2806 11 - - SYM cord-015369-72cjogxz 2806 12 205 205 CD cord-015369-72cjogxz 2806 13 min min NN cord-015369-72cjogxz 2806 14 for for IN cord-015369-72cjogxz 2806 15 single single JJ cord-015369-72cjogxz 2806 16 and and CC cord-015369-72cjogxz 2806 17 bilateral bilateral JJ cord-015369-72cjogxz 2806 18 repair repair NN cord-015369-72cjogxz 2806 19 , , , cord-015369-72cjogxz 2806 20 respectively respectively RB cord-015369-72cjogxz 2806 21 . . . cord-015369-72cjogxz 2807 1 One one CD cord-015369-72cjogxz 2807 2 additional additional JJ cord-015369-72cjogxz 2807 3 trocar trocar NN cord-015369-72cjogxz 2807 4 had have VBD cord-015369-72cjogxz 2807 5 to to TO cord-015369-72cjogxz 2807 6 be be VB cord-015369-72cjogxz 2807 7 placed place VBN cord-015369-72cjogxz 2807 8 for for IN cord-015369-72cjogxz 2807 9 dissection dissection NN cord-015369-72cjogxz 2807 10 or or CC cord-015369-72cjogxz 2807 11 suturing suturing NN cord-015369-72cjogxz 2807 12 in in IN cord-015369-72cjogxz 2807 13 four four CD cord-015369-72cjogxz 2807 14 patients patient NNS cord-015369-72cjogxz 2807 15 . . . cord-015369-72cjogxz 2808 1 No no DT cord-015369-72cjogxz 2808 2 intraoperative intraoperative JJ cord-015369-72cjogxz 2808 3 adverse adverse JJ cord-015369-72cjogxz 2808 4 events event NNS cord-015369-72cjogxz 2808 5 or or CC cord-015369-72cjogxz 2808 6 significant significant JJ cord-015369-72cjogxz 2808 7 perioperative perioperative JJ cord-015369-72cjogxz 2808 8 complication complication NN cord-015369-72cjogxz 2808 9 was be VBD cord-015369-72cjogxz 2808 10 noticed notice VBN cord-015369-72cjogxz 2808 11 . . . cord-015369-72cjogxz 2809 1 Estimated estimate VBN cord-015369-72cjogxz 2809 2 blood blood NN cord-015369-72cjogxz 2809 3 loss loss NN cord-015369-72cjogxz 2809 4 yielded yield VBD cord-015369-72cjogxz 2809 5 minimal minimal JJ cord-015369-72cjogxz 2809 6 in in IN cord-015369-72cjogxz 2809 7 all all DT cord-015369-72cjogxz 2809 8 cases case NNS cord-015369-72cjogxz 2809 9 . . . cord-015369-72cjogxz 2810 1 In in IN cord-015369-72cjogxz 2810 2 one one CD cord-015369-72cjogxz 2810 3 patient patient NN cord-015369-72cjogxz 2810 4 redolaparoscopy redolaparoscopy NNP cord-015369-72cjogxz 2810 5 was be VBD cord-015369-72cjogxz 2810 6 carried carry VBN cord-015369-72cjogxz 2810 7 out out RP cord-015369-72cjogxz 2810 8 after after IN cord-015369-72cjogxz 2810 9 23 23 CD cord-015369-72cjogxz 2810 10 days day NNS cord-015369-72cjogxz 2810 11 for for IN cord-015369-72cjogxz 2810 12 undefined undefined JJ cord-015369-72cjogxz 2810 13 lower low JJR cord-015369-72cjogxz 2810 14 abdominal abdominal JJ cord-015369-72cjogxz 2810 15 pain pain NN cord-015369-72cjogxz 2810 16 . . . cord-015369-72cjogxz 2811 1 Oral oral JJ cord-015369-72cjogxz 2811 2 diet diet NN cord-015369-72cjogxz 2811 3 was be VBD cord-015369-72cjogxz 2811 4 resumed resume VBN cord-015369-72cjogxz 2811 5 immediately immediately RB cord-015369-72cjogxz 2811 6 after after IN cord-015369-72cjogxz 2811 7 the the DT cord-015369-72cjogxz 2811 8 operation operation NN cord-015369-72cjogxz 2811 9 . . . cord-015369-72cjogxz 2812 1 Patients patient NNS cord-015369-72cjogxz 2812 2 were be VBD cord-015369-72cjogxz 2812 3 discharged discharge VBN cord-015369-72cjogxz 2812 4 on on IN cord-015369-72cjogxz 2812 5 postoperative postoperative JJ cord-015369-72cjogxz 2812 6 day day NN cord-015369-72cjogxz 2812 7 2 2 CD cord-015369-72cjogxz 2812 8 to to IN cord-015369-72cjogxz 2812 9 4 4 CD cord-015369-72cjogxz 2812 10 in in IN cord-015369-72cjogxz 2812 11 accordance accordance NN cord-015369-72cjogxz 2812 12 with with IN cord-015369-72cjogxz 2812 13 local local JJ cord-015369-72cjogxz 2812 14 custom custom NN cord-015369-72cjogxz 2812 15 . . . cord-015369-72cjogxz 2813 1 At at IN cord-015369-72cjogxz 2813 2 follow follow VB cord-015369-72cjogxz 2813 3 - - HYPH cord-015369-72cjogxz 2813 4 up up RP cord-015369-72cjogxz 2813 5 patients patient NNS cord-015369-72cjogxz 2813 6 presented present VBN cord-015369-72cjogxz 2813 7 with with IN cord-015369-72cjogxz 2813 8 an an DT cord-015369-72cjogxz 2813 9 optimal optimal JJ cord-015369-72cjogxz 2813 10 postoperative postoperative JJ cord-015369-72cjogxz 2813 11 and and CC cord-015369-72cjogxz 2813 12 cosmetic cosmetic JJ cord-015369-72cjogxz 2813 13 result result NN cord-015369-72cjogxz 2813 14 without without IN cord-015369-72cjogxz 2813 15 apparent apparent JJ cord-015369-72cjogxz 2813 16 scarring scarring NN cord-015369-72cjogxz 2813 17 . . . cord-015369-72cjogxz 2814 1 Conclusions conclusion NNS cord-015369-72cjogxz 2814 2 . . . cord-015369-72cjogxz 2815 1 This this DT cord-015369-72cjogxz 2815 2 feasibility feasibility NN cord-015369-72cjogxz 2815 3 study study NN cord-015369-72cjogxz 2815 4 presents present VBZ cord-015369-72cjogxz 2815 5 for for IN cord-015369-72cjogxz 2815 6 the the DT cord-015369-72cjogxz 2815 7 first first JJ cord-015369-72cjogxz 2815 8 time time NN cord-015369-72cjogxz 2815 9 presents present VBZ cord-015369-72cjogxz 2815 10 a a DT cord-015369-72cjogxz 2815 11 novel novel JJ cord-015369-72cjogxz 2815 12 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2815 13 technique technique NN cord-015369-72cjogxz 2815 14 for for IN cord-015369-72cjogxz 2815 15 TAPP TAPP NNP cord-015369-72cjogxz 2815 16 groin groin NNP cord-015369-72cjogxz 2815 17 hernia hernia NNP cord-015369-72cjogxz 2815 18 repair repair NN cord-015369-72cjogxz 2815 19 utilizing utilize VBG cord-015369-72cjogxz 2815 20 a a DT cord-015369-72cjogxz 2815 21 single single JJ cord-015369-72cjogxz 2815 22 ' ' '' cord-015369-72cjogxz 2815 23 ' ' '' cord-015369-72cjogxz 2815 24 scar scar NN cord-015369-72cjogxz 2815 25 - - HYPH cord-015369-72cjogxz 2815 26 less less NN cord-015369-72cjogxz 2815 27 ' ' '' cord-015369-72cjogxz 2815 28 ' ' '' cord-015369-72cjogxz 2815 29 intraumbilical intraumbilical NNP cord-015369-72cjogxz 2815 30 approach approach NN cord-015369-72cjogxz 2815 31 which which WDT cord-015369-72cjogxz 2815 32 allows allow VBZ cord-015369-72cjogxz 2815 33 further further JJ cord-015369-72cjogxz 2815 34 reduction reduction NN cord-015369-72cjogxz 2815 35 of of IN cord-015369-72cjogxz 2815 36 the the DT cord-015369-72cjogxz 2815 37 surgical surgical JJ cord-015369-72cjogxz 2815 38 trauma trauma NN cord-015369-72cjogxz 2815 39 . . . cord-015369-72cjogxz 2816 1 Background background NN cord-015369-72cjogxz 2816 2 . . . cord-015369-72cjogxz 2817 1 On on IN cord-015369-72cjogxz 2817 2 the the DT cord-015369-72cjogxz 2817 3 way way NN cord-015369-72cjogxz 2817 4 to to TO cord-015369-72cjogxz 2817 5 ' ' '' cord-015369-72cjogxz 2817 6 ' ' '' cord-015369-72cjogxz 2817 7 no no DT cord-015369-72cjogxz 2817 8 - - HYPH cord-015369-72cjogxz 2817 9 scar scar NN cord-015369-72cjogxz 2817 10 ' ' '' cord-015369-72cjogxz 2817 11 ' ' '' cord-015369-72cjogxz 2817 12 techniques technique NNS cord-015369-72cjogxz 2817 13 we -PRON- PRP cord-015369-72cjogxz 2817 14 developed develop VBD cord-015369-72cjogxz 2817 15 a a DT cord-015369-72cjogxz 2817 16 novel novel JJ cord-015369-72cjogxz 2817 17 method method NN cord-015369-72cjogxz 2817 18 for for IN cord-015369-72cjogxz 2817 19 colorectal colorectal JJ cord-015369-72cjogxz 2817 20 resection resection NN cord-015369-72cjogxz 2817 21 utilizing utilize VBG cord-015369-72cjogxz 2817 22 three three CD cord-015369-72cjogxz 2817 23 intraumbilical intraumbilical NNP cord-015369-72cjogxz 2817 24 trocars trocar NNS cord-015369-72cjogxz 2817 25 which which WDT cord-015369-72cjogxz 2817 26 results result VBZ cord-015369-72cjogxz 2817 27 in in IN cord-015369-72cjogxz 2817 28 a a DT cord-015369-72cjogxz 2817 29 non non JJ cord-015369-72cjogxz 2817 30 - - JJ cord-015369-72cjogxz 2817 31 visible visible JJ cord-015369-72cjogxz 2817 32 postoperative postoperative JJ cord-015369-72cjogxz 2817 33 scar scar NN cord-015369-72cjogxz 2817 34 . . . cord-015369-72cjogxz 2818 1 Methods method NNS cord-015369-72cjogxz 2818 2 . . . cord-015369-72cjogxz 2819 1 Four four CD cord-015369-72cjogxz 2819 2 patients patient NNS cord-015369-72cjogxz 2819 3 ( ( -LRB- cord-015369-72cjogxz 2819 4 3 3 CD cord-015369-72cjogxz 2819 5 female/1 female/1 NN cord-015369-72cjogxz 2819 6 male male NN cord-015369-72cjogxz 2819 7 ; ; : cord-015369-72cjogxz 2819 8 42 42 CD cord-015369-72cjogxz 2819 9 - - HYPH cord-015369-72cjogxz 2819 10 65a 65a CD cord-015369-72cjogxz 2819 11 ) ) -RRB- cord-015369-72cjogxz 2819 12 underwent undergo VBD cord-015369-72cjogxz 2819 13 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2819 14 colorectal colorectal JJ cord-015369-72cjogxz 2819 15 resection resection NN cord-015369-72cjogxz 2819 16 for for IN cord-015369-72cjogxz 2819 17 diverticulitis diverticulitis NN cord-015369-72cjogxz 2819 18 and and CC cord-015369-72cjogxz 2819 19 infiltrating infiltrate VBG cord-015369-72cjogxz 2819 20 endometriosis endometriosis NN cord-015369-72cjogxz 2819 21 of of IN cord-015369-72cjogxz 2819 22 the the DT cord-015369-72cjogxz 2819 23 rectosigmoid rectosigmoid JJ cord-015369-72cjogxz 2819 24 colon colon NN cord-015369-72cjogxz 2819 25 , , , cord-015369-72cjogxz 2819 26 respectively respectively RB cord-015369-72cjogxz 2819 27 . . . cord-015369-72cjogxz 2820 1 The the DT cord-015369-72cjogxz 2820 2 entire entire JJ cord-015369-72cjogxz 2820 3 operation operation NN cord-015369-72cjogxz 2820 4 was be VBD cord-015369-72cjogxz 2820 5 carried carry VBN cord-015369-72cjogxz 2820 6 out out RP cord-015369-72cjogxz 2820 7 transumbilically transumbilically RB cord-015369-72cjogxz 2820 8 following follow VBG cord-015369-72cjogxz 2820 9 the the DT cord-015369-72cjogxz 2820 10 standardized standardized JJ cord-015369-72cjogxz 2820 11 principles principle NNS cord-015369-72cjogxz 2820 12 of of IN cord-015369-72cjogxz 2820 13 colorectal colorectal JJ cord-015369-72cjogxz 2820 14 resection resection NN cord-015369-72cjogxz 2820 15 . . . cord-015369-72cjogxz 2821 1 Results result NNS cord-015369-72cjogxz 2821 2 . . . cord-015369-72cjogxz 2822 1 The the DT cord-015369-72cjogxz 2822 2 operative operative JJ cord-015369-72cjogxz 2822 3 time time NN cord-015369-72cjogxz 2822 4 ranged range VBD cord-015369-72cjogxz 2822 5 in in IN cord-015369-72cjogxz 2822 6 total total NN cord-015369-72cjogxz 2822 7 from from IN cord-015369-72cjogxz 2822 8 85 85 CD cord-015369-72cjogxz 2822 9 min min NN cord-015369-72cjogxz 2822 10 to to IN cord-015369-72cjogxz 2822 11 180 180 CD cord-015369-72cjogxz 2822 12 min min NN cord-015369-72cjogxz 2822 13 and and CC cord-015369-72cjogxz 2822 14 for for IN cord-015369-72cjogxz 2822 15 dissection dissection NN cord-015369-72cjogxz 2822 16 only only RB cord-015369-72cjogxz 2822 17 75 75 CD cord-015369-72cjogxz 2822 18 - - SYM cord-015369-72cjogxz 2822 19 155 155 CD cord-015369-72cjogxz 2822 20 min min NN cord-015369-72cjogxz 2822 21 , , , cord-015369-72cjogxz 2822 22 respectively respectively RB cord-015369-72cjogxz 2822 23 . . . cord-015369-72cjogxz 2823 1 No no DT cord-015369-72cjogxz 2823 2 intraoperative intraoperative JJ cord-015369-72cjogxz 2823 3 adverse adverse JJ cord-015369-72cjogxz 2823 4 events event NNS cord-015369-72cjogxz 2823 5 or or CC cord-015369-72cjogxz 2823 6 significant significant JJ cord-015369-72cjogxz 2823 7 perioperative perioperative JJ cord-015369-72cjogxz 2823 8 complications complication NNS cord-015369-72cjogxz 2823 9 were be VBD cord-015369-72cjogxz 2823 10 noticed notice VBN cord-015369-72cjogxz 2823 11 . . . cord-015369-72cjogxz 2824 1 Specimen specimen JJ cord-015369-72cjogxz 2824 2 retrieval retrieval NN cord-015369-72cjogxz 2824 3 was be VBD cord-015369-72cjogxz 2824 4 carried carry VBN cord-015369-72cjogxz 2824 5 out out RP cord-015369-72cjogxz 2824 6 through through IN cord-015369-72cjogxz 2824 7 the the DT cord-015369-72cjogxz 2824 8 umbilicus umbilicus NN cord-015369-72cjogxz 2824 9 . . . cord-015369-72cjogxz 2825 1 Segments segment NNS cord-015369-72cjogxz 2825 2 measured measure VBN cord-015369-72cjogxz 2825 3 in in IN cord-015369-72cjogxz 2825 4 length length NN cord-015369-72cjogxz 2825 5 18 18 CD cord-015369-72cjogxz 2825 6 cm cm NNS cord-015369-72cjogxz 2825 7 to to IN cord-015369-72cjogxz 2825 8 22 22 CD cord-015369-72cjogxz 2825 9 cm cm NNS cord-015369-72cjogxz 2825 10 . . . cord-015369-72cjogxz 2826 1 Circular circular JJ cord-015369-72cjogxz 2826 2 stapled staple VBN cord-015369-72cjogxz 2826 3 anastomosis anastomosis NN cord-015369-72cjogxz 2826 4 was be VBD cord-015369-72cjogxz 2826 5 performed perform VBN cord-015369-72cjogxz 2826 6 transanally transanally RB cord-015369-72cjogxz 2826 7 . . . cord-015369-72cjogxz 2827 1 Estimated estimate VBN cord-015369-72cjogxz 2827 2 blood blood NN cord-015369-72cjogxz 2827 3 loss loss NN cord-015369-72cjogxz 2827 4 yielded yield VBD cord-015369-72cjogxz 2827 5 minimal minimal JJ cord-015369-72cjogxz 2827 6 in in IN cord-015369-72cjogxz 2827 7 all all DT cord-015369-72cjogxz 2827 8 cases case NNS cord-015369-72cjogxz 2827 9 . . . cord-015369-72cjogxz 2828 1 Oral oral JJ cord-015369-72cjogxz 2828 2 diet diet NN cord-015369-72cjogxz 2828 3 was be VBD cord-015369-72cjogxz 2828 4 resumed resume VBN cord-015369-72cjogxz 2828 5 on on IN cord-015369-72cjogxz 2828 6 postoperative postoperative JJ cord-015369-72cjogxz 2828 7 day day NN cord-015369-72cjogxz 2828 8 1 1 CD cord-015369-72cjogxz 2828 9 . . . cord-015369-72cjogxz 2829 1 Patients patient NNS cord-015369-72cjogxz 2829 2 were be VBD cord-015369-72cjogxz 2829 3 discharged discharge VBN cord-015369-72cjogxz 2829 4 on on IN cord-015369-72cjogxz 2829 5 postoperative postoperative JJ cord-015369-72cjogxz 2829 6 day day NN cord-015369-72cjogxz 2829 7 6 6 CD cord-015369-72cjogxz 2829 8 to to IN cord-015369-72cjogxz 2829 9 8 8 CD cord-015369-72cjogxz 2829 10 . . . cord-015369-72cjogxz 2830 1 At at IN cord-015369-72cjogxz 2830 2 follow follow VB cord-015369-72cjogxz 2830 3 - - HYPH cord-015369-72cjogxz 2830 4 up up RP cord-015369-72cjogxz 2830 5 patients patient NNS cord-015369-72cjogxz 2830 6 presented present VBN cord-015369-72cjogxz 2830 7 with with IN cord-015369-72cjogxz 2830 8 an an DT cord-015369-72cjogxz 2830 9 optimal optimal JJ cord-015369-72cjogxz 2830 10 cosmetic cosmetic NN cord-015369-72cjogxz 2830 11 result result NN cord-015369-72cjogxz 2830 12 without without IN cord-015369-72cjogxz 2830 13 apparent apparent JJ cord-015369-72cjogxz 2830 14 scarring scarring NN cord-015369-72cjogxz 2830 15 . . . cord-015369-72cjogxz 2831 1 Conclusions conclusion NNS cord-015369-72cjogxz 2831 2 . . . cord-015369-72cjogxz 2832 1 For for IN cord-015369-72cjogxz 2832 2 the the DT cord-015369-72cjogxz 2832 3 first first JJ cord-015369-72cjogxz 2832 4 time time NN cord-015369-72cjogxz 2832 5 a a DT cord-015369-72cjogxz 2832 6 novel novel JJ cord-015369-72cjogxz 2832 7 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2832 8 technique technique NN cord-015369-72cjogxz 2832 9 for for IN cord-015369-72cjogxz 2832 10 sigmoid sigmoid JJ cord-015369-72cjogxz 2832 11 colon colon NN cord-015369-72cjogxz 2832 12 resection resection NN cord-015369-72cjogxz 2832 13 utilizing utilize VBG cord-015369-72cjogxz 2832 14 a a DT cord-015369-72cjogxz 2832 15 single single JJ cord-015369-72cjogxz 2832 16 intraumbilical intraumbilical JJ cord-015369-72cjogxz 2832 17 approach approach NN cord-015369-72cjogxz 2832 18 is be VBZ cord-015369-72cjogxz 2832 19 presented present VBN cord-015369-72cjogxz 2832 20 . . . cord-015369-72cjogxz 2833 1 This this DT cord-015369-72cjogxz 2833 2 new new JJ cord-015369-72cjogxz 2833 3 method method NN cord-015369-72cjogxz 2833 4 is be VBZ cord-015369-72cjogxz 2833 5 restricted restrict VBN cord-015369-72cjogxz 2833 6 to to IN cord-015369-72cjogxz 2833 7 a a DT cord-015369-72cjogxz 2833 8 limited limited JJ cord-015369-72cjogxz 2833 9 number number NN cord-015369-72cjogxz 2833 10 of of IN cord-015369-72cjogxz 2833 11 patients patient NNS cord-015369-72cjogxz 2833 12 but but CC cord-015369-72cjogxz 2833 13 allows allow VBZ cord-015369-72cjogxz 2833 14 further further JJ cord-015369-72cjogxz 2833 15 reduction reduction NN cord-015369-72cjogxz 2833 16 of of IN cord-015369-72cjogxz 2833 17 the the DT cord-015369-72cjogxz 2833 18 surgical surgical JJ cord-015369-72cjogxz 2833 19 trauma trauma NN cord-015369-72cjogxz 2833 20 and and CC cord-015369-72cjogxz 2833 21 to to TO cord-015369-72cjogxz 2833 22 obviate obviate VB cord-015369-72cjogxz 2833 23 any any DT cord-015369-72cjogxz 2833 24 visible visible JJ cord-015369-72cjogxz 2833 25 scar scar NN cord-015369-72cjogxz 2833 26 . . . cord-015369-72cjogxz 2834 1 Background background NN cord-015369-72cjogxz 2834 2 . . . cord-015369-72cjogxz 2835 1 Besides besides IN cord-015369-72cjogxz 2835 2 the the DT cord-015369-72cjogxz 2835 3 considerable considerable JJ cord-015369-72cjogxz 2835 4 advantages advantage NNS cord-015369-72cjogxz 2835 5 of of IN cord-015369-72cjogxz 2835 6 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2835 7 ventral ventral JJ cord-015369-72cjogxz 2835 8 hernia hernia NN cord-015369-72cjogxz 2835 9 repair repair NN cord-015369-72cjogxz 2835 10 one one CD cord-015369-72cjogxz 2835 11 of of IN cord-015369-72cjogxz 2835 12 the the DT cord-015369-72cjogxz 2835 13 most most RBS cord-015369-72cjogxz 2835 14 severe severe JJ cord-015369-72cjogxz 2835 15 complication complication NN cord-015369-72cjogxz 2835 16 is be VBZ cord-015369-72cjogxz 2835 17 the the DT cord-015369-72cjogxz 2835 18 incisional incisional JJ cord-015369-72cjogxz 2835 19 hernia hernia NN cord-015369-72cjogxz 2835 20 of of IN cord-015369-72cjogxz 2835 21 the the DT cord-015369-72cjogxz 2835 22 trocar trocar NNP cord-015369-72cjogxz 2835 23 site site NN cord-015369-72cjogxz 2835 24 . . . cord-015369-72cjogxz 2836 1 One one CD cord-015369-72cjogxz 2836 2 of of IN cord-015369-72cjogxz 2836 3 the the DT cord-015369-72cjogxz 2836 4 key key JJ cord-015369-72cjogxz 2836 5 benefits benefit NNS cord-015369-72cjogxz 2836 6 of of IN cord-015369-72cjogxz 2836 7 NOTES note NNS cord-015369-72cjogxz 2836 8 - - HYPH cord-015369-72cjogxz 2836 9 procedures procedure NNS cord-015369-72cjogxz 2836 10 is be VBZ cord-015369-72cjogxz 2836 11 to to TO cord-015369-72cjogxz 2836 12 avoid avoid VB cord-015369-72cjogxz 2836 13 surface surface NN cord-015369-72cjogxz 2836 14 incisions incision NNS cord-015369-72cjogxz 2836 15 leading lead VBG cord-015369-72cjogxz 2836 16 to to IN cord-015369-72cjogxz 2836 17 a a DT cord-015369-72cjogxz 2836 18 decrease decrease NN cord-015369-72cjogxz 2836 19 of of IN cord-015369-72cjogxz 2836 20 postoperative postoperative JJ cord-015369-72cjogxz 2836 21 pain pain NN cord-015369-72cjogxz 2836 22 , , , cord-015369-72cjogxz 2836 23 infection infection NN cord-015369-72cjogxz 2836 24 and and CC cord-015369-72cjogxz 2836 25 port port NN cord-015369-72cjogxz 2836 26 site site NN cord-015369-72cjogxz 2836 27 hernia hernia NN cord-015369-72cjogxz 2836 28 . . . cord-015369-72cjogxz 2837 1 The the DT cord-015369-72cjogxz 2837 2 aim aim NN cord-015369-72cjogxz 2837 3 of of IN cord-015369-72cjogxz 2837 4 this this DT cord-015369-72cjogxz 2837 5 experimental experimental JJ cord-015369-72cjogxz 2837 6 study study NN cord-015369-72cjogxz 2837 7 was be VBD cord-015369-72cjogxz 2837 8 to to TO cord-015369-72cjogxz 2837 9 assess assess VB cord-015369-72cjogxz 2837 10 the the DT cord-015369-72cjogxz 2837 11 feasibility feasibility NN cord-015369-72cjogxz 2837 12 of of IN cord-015369-72cjogxz 2837 13 the the DT cord-015369-72cjogxz 2837 14 IPOM IPOM NNP cord-015369-72cjogxz 2837 15 repair repair NN cord-015369-72cjogxz 2837 16 in in IN cord-015369-72cjogxz 2837 17 ventral ventral JJ cord-015369-72cjogxz 2837 18 hernia hernia NN cord-015369-72cjogxz 2837 19 by by IN cord-015369-72cjogxz 2837 20 transgastric transgastric JJ cord-015369-72cjogxz 2837 21 access access NN cord-015369-72cjogxz 2837 22 in in IN cord-015369-72cjogxz 2837 23 a a DT cord-015369-72cjogxz 2837 24 pig pig NN cord-015369-72cjogxz 2837 25 model model NN cord-015369-72cjogxz 2837 26 . . . cord-015369-72cjogxz 2838 1 Methods method NNS cord-015369-72cjogxz 2838 2 . . . cord-015369-72cjogxz 2839 1 Under under IN cord-015369-72cjogxz 2839 2 laparoscopic laparoscopic NNP cord-015369-72cjogxz 2839 3 control control VB cord-015369-72cjogxz 2839 4 a a DT cord-015369-72cjogxz 2839 5 transgastric transgastric JJ cord-015369-72cjogxz 2839 6 approach approach NN cord-015369-72cjogxz 2839 7 was be VBD cord-015369-72cjogxz 2839 8 utilized utilize VBN cord-015369-72cjogxz 2839 9 to to TO cord-015369-72cjogxz 2839 10 create create VB cord-015369-72cjogxz 2839 11 4 4 CD cord-015369-72cjogxz 2839 12 abdominal abdominal JJ cord-015369-72cjogxz 2839 13 wall wall NN cord-015369-72cjogxz 2839 14 defects defect NNS cord-015369-72cjogxz 2839 15 in in IN cord-015369-72cjogxz 2839 16 5 5 CD cord-015369-72cjogxz 2839 17 female female JJ cord-015369-72cjogxz 2839 18 , , , cord-015369-72cjogxz 2839 19 domestic domestic JJ cord-015369-72cjogxz 2839 20 nonsurvival nonsurvival NN cord-015369-72cjogxz 2839 21 and and CC cord-015369-72cjogxz 2839 22 3 3 CD cord-015369-72cjogxz 2839 23 survival survival NN cord-015369-72cjogxz 2839 24 pigs pig NNS cord-015369-72cjogxz 2839 25 respectively respectively RB cord-015369-72cjogxz 2839 26 . . . cord-015369-72cjogxz 2840 1 Titanized titanized JJ cord-015369-72cjogxz 2840 2 polypropylene polypropylene NN cord-015369-72cjogxz 2840 3 meshes mesh NNS cord-015369-72cjogxz 2840 4 ( ( -LRB- cord-015369-72cjogxz 2840 5 TiSure tisure NN cord-015369-72cjogxz 2840 6 + + CC cord-015369-72cjogxz 2840 7 ) ) -RRB- cord-015369-72cjogxz 2840 8 armed arm VBN cord-015369-72cjogxz 2840 9 by by IN cord-015369-72cjogxz 2840 10 polypropylene polypropylene NN cord-015369-72cjogxz 2840 11 sutures suture NNS cord-015369-72cjogxz 2840 12 in in IN cord-015369-72cjogxz 2840 13 the the DT cord-015369-72cjogxz 2840 14 four four CD cord-015369-72cjogxz 2840 15 corners corner NNS cord-015369-72cjogxz 2840 16 were be VBD cord-015369-72cjogxz 2840 17 transferred transfer VBN cord-015369-72cjogxz 2840 18 via via IN cord-015369-72cjogxz 2840 19 the the DT cord-015369-72cjogxz 2840 20 umbilical umbilical JJ cord-015369-72cjogxz 2840 21 trocar trocar NN cord-015369-72cjogxz 2840 22 . . . cord-015369-72cjogxz 2841 1 After after IN cord-015369-72cjogxz 2841 2 suture suture NN cord-015369-72cjogxz 2841 3 fixation fixation NN cord-015369-72cjogxz 2841 4 of of IN cord-015369-72cjogxz 2841 5 each each DT cord-015369-72cjogxz 2841 6 mesh mesh VB cord-015369-72cjogxz 2841 7 additional additional JJ cord-015369-72cjogxz 2841 8 endoscopic endoscopic JJ cord-015369-72cjogxz 2841 9 transporous transporous JJ cord-015369-72cjogxz 2841 10 fibrin fibrin NN cord-015369-72cjogxz 2841 11 sealant sealant NN cord-015369-72cjogxz 2841 12 fixation fixation NN cord-015369-72cjogxz 2841 13 ( ( -LRB- cord-015369-72cjogxz 2841 14 Tissucol Tissucol NNP cord-015369-72cjogxz 2841 15 + + CC cord-015369-72cjogxz 2841 16 ) ) -RRB- cord-015369-72cjogxz 2841 17 using use VBG cord-015369-72cjogxz 2841 18 a a DT cord-015369-72cjogxz 2841 19 single single JJ cord-015369-72cjogxz 2841 20 lumen lumen JJ cord-015369-72cjogxz 2841 21 catheter catheter NN cord-015369-72cjogxz 2841 22 was be VBD cord-015369-72cjogxz 2841 23 performed perform VBN cord-015369-72cjogxz 2841 24 . . . cord-015369-72cjogxz 2842 1 The the DT cord-015369-72cjogxz 2842 2 closure closure NN cord-015369-72cjogxz 2842 3 of of IN cord-015369-72cjogxz 2842 4 the the DT cord-015369-72cjogxz 2842 5 gastric gastric JJ cord-015369-72cjogxz 2842 6 access access NN cord-015369-72cjogxz 2842 7 was be VBD cord-015369-72cjogxz 2842 8 achieved achieve VBN cord-015369-72cjogxz 2842 9 by by IN cord-015369-72cjogxz 2842 10 applying apply VBG cord-015369-72cjogxz 2842 11 endoclips endoclips NNP cord-015369-72cjogxz 2842 12 in in IN cord-015369-72cjogxz 2842 13 nonsurvival nonsurvival NNP cord-015369-72cjogxz 2842 14 and and CC cord-015369-72cjogxz 2842 15 by by IN cord-015369-72cjogxz 2842 16 laparoscopic laparoscopic JJ cord-015369-72cjogxz 2842 17 suturing suturing NN cord-015369-72cjogxz 2842 18 in in IN cord-015369-72cjogxz 2842 19 case case NN cord-015369-72cjogxz 2842 20 of of IN cord-015369-72cjogxz 2842 21 survival survival NN cord-015369-72cjogxz 2842 22 pigs pig NNS cord-015369-72cjogxz 2842 23 respectively respectively RB cord-015369-72cjogxz 2842 24 . . . cord-015369-72cjogxz 2843 1 Results result NNS cord-015369-72cjogxz 2843 2 . . . cord-015369-72cjogxz 2844 1 The the DT cord-015369-72cjogxz 2844 2 3 3 CD cord-015369-72cjogxz 2844 3 survival survival NN cord-015369-72cjogxz 2844 4 pigs pig NNS cord-015369-72cjogxz 2844 5 were be VBD cord-015369-72cjogxz 2844 6 euthanized euthanize VBN cord-015369-72cjogxz 2844 7 at at IN cord-015369-72cjogxz 2844 8 day day NN cord-015369-72cjogxz 2844 9 4 4 CD cord-015369-72cjogxz 2844 10 , , , cord-015369-72cjogxz 2844 11 11 11 CD cord-015369-72cjogxz 2844 12 and and CC cord-015369-72cjogxz 2844 13 22 22 CD cord-015369-72cjogxz 2844 14 postoperatively postoperatively NN cord-015369-72cjogxz 2844 15 . . . cord-015369-72cjogxz 2845 1 The the DT cord-015369-72cjogxz 2845 2 macroscopical macroscopical JJ cord-015369-72cjogxz 2845 3 evaluation evaluation NN cord-015369-72cjogxz 2845 4 revealed reveal VBD cord-015369-72cjogxz 2845 5 excellent excellent JJ cord-015369-72cjogxz 2845 6 integration integration NN cord-015369-72cjogxz 2845 7 of of IN cord-015369-72cjogxz 2845 8 the the DT cord-015369-72cjogxz 2845 9 meshes mesh NNS cord-015369-72cjogxz 2845 10 without without IN cord-015369-72cjogxz 2845 11 signs sign NNS cord-015369-72cjogxz 2845 12 of of IN cord-015369-72cjogxz 2845 13 shrinkage shrinkage NN cord-015369-72cjogxz 2845 14 or or CC cord-015369-72cjogxz 2845 15 increased increase VBN cord-015369-72cjogxz 2845 16 inflammation inflammation NN cord-015369-72cjogxz 2845 17 . . . cord-015369-72cjogxz 2846 1 Only only RB cord-015369-72cjogxz 2846 2 in in IN cord-015369-72cjogxz 2846 3 2 2 CD cord-015369-72cjogxz 2846 4 cases case NNS cord-015369-72cjogxz 2846 5 out out IN cord-015369-72cjogxz 2846 6 of of IN cord-015369-72cjogxz 2846 7 a a DT cord-015369-72cjogxz 2846 8 total total NN cord-015369-72cjogxz 2846 9 of of IN cord-015369-72cjogxz 2846 10 12 12 CD cord-015369-72cjogxz 2846 11 meshes mesh NNS cord-015369-72cjogxz 2846 12 minimal minimal JJ cord-015369-72cjogxz 2846 13 adhesions adhesion NNS cord-015369-72cjogxz 2846 14 in in IN cord-015369-72cjogxz 2846 15 the the DT cord-015369-72cjogxz 2846 16 region region NN cord-015369-72cjogxz 2846 17 of of IN cord-015369-72cjogxz 2846 18 suture suture NN cord-015369-72cjogxz 2846 19 fixation fixation NN cord-015369-72cjogxz 2846 20 were be VBD cord-015369-72cjogxz 2846 21 observed observe VBN cord-015369-72cjogxz 2846 22 . . . cord-015369-72cjogxz 2847 1 Histology histology NN cord-015369-72cjogxz 2847 2 confirmed confirm VBD cord-015369-72cjogxz 2847 3 the the DT cord-015369-72cjogxz 2847 4 macroscopical macroscopical JJ cord-015369-72cjogxz 2847 5 findings finding NNS cord-015369-72cjogxz 2847 6 . . . cord-015369-72cjogxz 2848 1 Conclusions conclusion NNS cord-015369-72cjogxz 2848 2 . . . cord-015369-72cjogxz 2849 1 The the DT cord-015369-72cjogxz 2849 2 initial initial JJ cord-015369-72cjogxz 2849 3 results result NNS cord-015369-72cjogxz 2849 4 of of IN cord-015369-72cjogxz 2849 5 our -PRON- PRP$ cord-015369-72cjogxz 2849 6 experimental experimental JJ cord-015369-72cjogxz 2849 7 study study NN cord-015369-72cjogxz 2849 8 demonstrate demonstrate VBP cord-015369-72cjogxz 2849 9 the the DT cord-015369-72cjogxz 2849 10 feasibility feasibility NN cord-015369-72cjogxz 2849 11 of of IN cord-015369-72cjogxz 2849 12 a a DT cord-015369-72cjogxz 2849 13 NOTES note NNS cord-015369-72cjogxz 2849 14 repair repair NN cord-015369-72cjogxz 2849 15 of of IN cord-015369-72cjogxz 2849 16 abdominal abdominal JJ cord-015369-72cjogxz 2849 17 wall wall NN cord-015369-72cjogxz 2849 18 hernias hernia NNS cord-015369-72cjogxz 2849 19 . . . cord-015369-72cjogxz 2850 1 Anticipating anticipate VBG cord-015369-72cjogxz 2850 2 technical technical JJ cord-015369-72cjogxz 2850 3 advances advance NNS cord-015369-72cjogxz 2850 4 of of IN cord-015369-72cjogxz 2850 5 NOTES note NNS cord-015369-72cjogxz 2850 6 - - : cord-015369-72cjogxz 2850 7 devices device NNS cord-015369-72cjogxz 2850 8 this this DT cord-015369-72cjogxz 2850 9 new new JJ cord-015369-72cjogxz 2850 10 technique technique NN cord-015369-72cjogxz 2850 11 could could MD cord-015369-72cjogxz 2850 12 be be VB cord-015369-72cjogxz 2850 13 auspicious auspicious JJ cord-015369-72cjogxz 2850 14 for for IN cord-015369-72cjogxz 2850 15 the the DT cord-015369-72cjogxz 2850 16 future future NN cord-015369-72cjogxz 2850 17 . . . cord-015369-72cjogxz 2851 1 Medical Medical NNP cord-015369-72cjogxz 2851 2 University University NNP cord-015369-72cjogxz 2851 3 , , , cord-015369-72cjogxz 2851 4 Lviv Lviv NNP cord-015369-72cjogxz 2851 5 , , , cord-015369-72cjogxz 2851 6 Ukraine Ukraine NNP cord-015369-72cjogxz 2851 7 ; ; : cord-015369-72cjogxz 2851 8 2 2 CD cord-015369-72cjogxz 2851 9 Childrens Childrens NNP cord-015369-72cjogxz 2851 10 Hospital Hospital NNP cord-015369-72cjogxz 2851 11 , , , cord-015369-72cjogxz 2851 12 Lviv Lviv NNP cord-015369-72cjogxz 2851 13 , , , cord-015369-72cjogxz 2852 1 Ukraine Ukraine NNP cord-015369-72cjogxz 2852 2 Recent recent JJ cord-015369-72cjogxz 2852 3 advances advance NNS cord-015369-72cjogxz 2852 4 in in IN cord-015369-72cjogxz 2852 5 medicine medicine NN cord-015369-72cjogxz 2852 6 brought bring VBN cord-015369-72cjogxz 2852 7 to to IN cord-015369-72cjogxz 2852 8 noticeable noticeable JJ cord-015369-72cjogxz 2852 9 growth growth NN cord-015369-72cjogxz 2852 10 of of IN cord-015369-72cjogxz 2852 11 premature premature JJ cord-015369-72cjogxz 2852 12 newborns newborn NNS cord-015369-72cjogxz 2852 13 ' ' POS cord-015369-72cjogxz 2852 14 survival survival NN cord-015369-72cjogxz 2852 15 value value NN cord-015369-72cjogxz 2852 16 . . . cord-015369-72cjogxz 2853 1 But but CC cord-015369-72cjogxz 2853 2 this this DT cord-015369-72cjogxz 2853 3 fact fact NN cord-015369-72cjogxz 2853 4 brought bring VBD cord-015369-72cjogxz 2853 5 to to IN cord-015369-72cjogxz 2853 6 growth growth NN cord-015369-72cjogxz 2853 7 of of IN cord-015369-72cjogxz 2853 8 necrotic necrotic JJ cord-015369-72cjogxz 2853 9 enterocolitis enterocolitis NN cord-015369-72cjogxz 2853 10 morbidity morbidity NN cord-015369-72cjogxz 2853 11 of of IN cord-015369-72cjogxz 2853 12 newborns newborn NNS cord-015369-72cjogxz 2853 13 that that WDT cord-015369-72cjogxz 2853 14 often often RB cord-015369-72cjogxz 2853 15 occurs occur VBZ cord-015369-72cjogxz 2853 16 on on IN cord-015369-72cjogxz 2853 17 the the DT cord-015369-72cjogxz 2853 18 background background NN cord-015369-72cjogxz 2853 19 of of IN cord-015369-72cjogxz 2853 20 congenital congenital JJ cord-015369-72cjogxz 2853 21 bowels bowel NNS cord-015369-72cjogxz 2853 22 pathology pathology NN cord-015369-72cjogxz 2853 23 . . . cord-015369-72cjogxz 2854 1 From from IN cord-015369-72cjogxz 2854 2 2007 2007 CD cord-015369-72cjogxz 2854 3 to to IN cord-015369-72cjogxz 2854 4 2009 2009 CD cord-015369-72cjogxz 2854 5 we -PRON- PRP cord-015369-72cjogxz 2854 6 treated treat VBD cord-015369-72cjogxz 2854 7 18 18 CD cord-015369-72cjogxz 2854 8 children child NNS cord-015369-72cjogxz 2854 9 with with IN cord-015369-72cjogxz 2854 10 necrotic necrotic JJ cord-015369-72cjogxz 2854 11 enterocolitis enterocolitis NN cord-015369-72cjogxz 2854 12 . . . cord-015369-72cjogxz 2855 1 The the DT cord-015369-72cjogxz 2855 2 average average JJ cord-015369-72cjogxz 2855 3 gestational gestational JJ cord-015369-72cjogxz 2855 4 age age NN cord-015369-72cjogxz 2855 5 of of IN cord-015369-72cjogxz 2855 6 patients patient NNS cord-015369-72cjogxz 2855 7 was be VBD cord-015369-72cjogxz 2855 8 32.7 32.7 CD cord-015369-72cjogxz 2855 9 þ þ CD cord-015369-72cjogxz 2855 10 2.4 2.4 CD cord-015369-72cjogxz 2855 11 weeks week NNS cord-015369-72cjogxz 2855 12 , , , cord-015369-72cjogxz 2855 13 average average JJ cord-015369-72cjogxz 2855 14 body body NN cord-015369-72cjogxz 2855 15 weight weight NN cord-015369-72cjogxz 2855 16 -1736 -1736 : cord-015369-72cjogxz 2855 17 þ þ NNP cord-015369-72cjogxz 2855 18 248 248 CD cord-015369-72cjogxz 2855 19 g. g. NNP cord-015369-72cjogxz 2855 20 Seven seven CD cord-015369-72cjogxz 2855 21 patients patient NNS cord-015369-72cjogxz 2855 22 were be VBD cord-015369-72cjogxz 2855 23 operated operate VBN cord-015369-72cjogxz 2855 24 with with IN cord-015369-72cjogxz 2855 25 3a 3a CD cord-015369-72cjogxz 2855 26 stage stage NN cord-015369-72cjogxz 2855 27 of of IN cord-015369-72cjogxz 2855 28 necrotic necrotic JJ cord-015369-72cjogxz 2855 29 enterocolitis enterocolitis NN cord-015369-72cjogxz 2855 30 . . . cord-015369-72cjogxz 2856 1 Large large JJ cord-015369-72cjogxz 2856 2 intestine intestine NN cord-015369-72cjogxz 2856 3 hypoplasia hypoplasia NN cord-015369-72cjogxz 2856 4 was be VBD cord-015369-72cjogxz 2856 5 intraoperatively intraoperatively RB cord-015369-72cjogxz 2856 6 revealed reveal VBN cord-015369-72cjogxz 2856 7 in in IN cord-015369-72cjogxz 2856 8 5 5 CD cord-015369-72cjogxz 2856 9 cases case NNS cord-015369-72cjogxz 2856 10 ; ; : cord-015369-72cjogxz 2856 11 and and CC cord-015369-72cjogxz 2856 12 after after IN cord-015369-72cjogxz 2856 13 its -PRON- PRP$ cord-015369-72cjogxz 2856 14 biopsy biopsy NN cord-015369-72cjogxz 2856 15 congenital congenital JJ cord-015369-72cjogxz 2856 16 agangliosis agangliosis NN cord-015369-72cjogxz 2856 17 was be VBD cord-015369-72cjogxz 2856 18 diagnosed diagnose VBN cord-015369-72cjogxz 2856 19 . . . cord-015369-72cjogxz 2857 1 The the DT cord-015369-72cjogxz 2857 2 signs sign NNS cord-015369-72cjogxz 2857 3 of of IN cord-015369-72cjogxz 2857 4 partial partial JJ cord-015369-72cjogxz 2857 5 bowel bowel NN cord-015369-72cjogxz 2857 6 obstruction obstruction NN cord-015369-72cjogxz 2857 7 kept keep VBN cord-015369-72cjogxz 2857 8 after after IN cord-015369-72cjogxz 2857 9 reduction reduction NN cord-015369-72cjogxz 2857 10 of of IN cord-015369-72cjogxz 2857 11 necrotic necrotic JJ cord-015369-72cjogxz 2857 12 enterocolitis enterocolitis NN cord-015369-72cjogxz 2857 13 effects effect NNS cord-015369-72cjogxz 2857 14 in in IN cord-015369-72cjogxz 2857 15 4 4 CD cord-015369-72cjogxz 2857 16 from from IN cord-015369-72cjogxz 2857 17 11 11 CD cord-015369-72cjogxz 2857 18 non non JJ cord-015369-72cjogxz 2857 19 - - JJ cord-015369-72cjogxz 2857 20 operated operate VBN cord-015369-72cjogxz 2857 21 patients patient NNS cord-015369-72cjogxz 2857 22 with with IN cord-015369-72cjogxz 2857 23 1b-2a 1b-2a CD cord-015369-72cjogxz 2857 24 stages stage NNS cord-015369-72cjogxz 2857 25 of of IN cord-015369-72cjogxz 2857 26 necrotic necrotic JJ cord-015369-72cjogxz 2857 27 enterocolitis enterocolitis NN cord-015369-72cjogxz 2857 28 ; ; : cord-015369-72cjogxz 2857 29 large large JJ cord-015369-72cjogxz 2857 30 intestine intestine NN cord-015369-72cjogxz 2857 31 biopsy biopsy NN cord-015369-72cjogxz 2857 32 of of IN cord-015369-72cjogxz 2857 33 those those DT cord-015369-72cjogxz 2857 34 patients patient NNS cord-015369-72cjogxz 2857 35 revealed reveal VBD cord-015369-72cjogxz 2857 36 intestinal intestinal JJ cord-015369-72cjogxz 2857 37 neuronal neuronal JJ cord-015369-72cjogxz 2857 38 displasia displasia NN cord-015369-72cjogxz 2857 39 type type NN cord-015369-72cjogxz 2857 40 A a NN cord-015369-72cjogxz 2857 41 in in IN cord-015369-72cjogxz 2857 42 one one CD cord-015369-72cjogxz 2857 43 case case NN cord-015369-72cjogxz 2857 44 , , , cord-015369-72cjogxz 2857 45 intestine intestine NN cord-015369-72cjogxz 2857 46 neuronal neuronal JJ cord-015369-72cjogxz 2857 47 displasia displasia NN cord-015369-72cjogxz 2857 48 type type NN cord-015369-72cjogxz 2857 49 B b NN cord-015369-72cjogxz 2857 50 in in IN cord-015369-72cjogxz 2857 51 two two CD cord-015369-72cjogxz 2857 52 cases case NNS cord-015369-72cjogxz 2857 53 , , , cord-015369-72cjogxz 2857 54 congenital congenital JJ cord-015369-72cjogxz 2857 55 agangliosis agangliosis NN cord-015369-72cjogxz 2857 56 in in IN cord-015369-72cjogxz 2857 57 one one CD cord-015369-72cjogxz 2857 58 case case NN cord-015369-72cjogxz 2857 59 . . . cord-015369-72cjogxz 2858 1 Conclusions conclusion NNS cord-015369-72cjogxz 2858 2 . . . cord-015369-72cjogxz 2859 1 Different different JJ cord-015369-72cjogxz 2859 2 forms form NNS cord-015369-72cjogxz 2859 3 of of IN cord-015369-72cjogxz 2859 4 disgangliosis disgangliosis NN cord-015369-72cjogxz 2859 5 can can MD cord-015369-72cjogxz 2859 6 be be VB cord-015369-72cjogxz 2859 7 one one CD cord-015369-72cjogxz 2859 8 of of IN cord-015369-72cjogxz 2859 9 the the DT cord-015369-72cjogxz 2859 10 trigger trigger NN cord-015369-72cjogxz 2859 11 mechanisms mechanism NNS cord-015369-72cjogxz 2859 12 for for IN cord-015369-72cjogxz 2859 13 the the DT cord-015369-72cjogxz 2859 14 development development NN cord-015369-72cjogxz 2859 15 of of IN cord-015369-72cjogxz 2859 16 newborns newborn NNS cord-015369-72cjogxz 2859 17 ' ' POS cord-015369-72cjogxz 2859 18 necrotic necrotic JJ cord-015369-72cjogxz 2859 19 enterocolitis enterocolitis NN cord-015369-72cjogxz 2859 20 . . . cord-015369-72cjogxz 2860 1 At at IN cord-015369-72cjogxz 2860 2 the the DT cord-015369-72cjogxz 2860 3 same same JJ cord-015369-72cjogxz 2860 4 moment moment NN cord-015369-72cjogxz 2860 5 necrotic necrotic JJ cord-015369-72cjogxz 2860 6 enterocolitis enterocolitis NN cord-015369-72cjogxz 2860 7 can can MD cord-015369-72cjogxz 2860 8 be be VB cord-015369-72cjogxz 2860 9 one one CD cord-015369-72cjogxz 2860 10 of of IN cord-015369-72cjogxz 2860 11 the the DT cord-015369-72cjogxz 2860 12 first first JJ cord-015369-72cjogxz 2860 13 manifestations manifestation NNS cord-015369-72cjogxz 2860 14 of of IN cord-015369-72cjogxz 2860 15 congenital congenital JJ cord-015369-72cjogxz 2860 16 disgangliosis disgangliosis NN cord-015369-72cjogxz 2860 17 . . . cord-015369-72cjogxz 2861 1 That that DT cord-015369-72cjogxz 2861 2 's be VBZ cord-015369-72cjogxz 2861 3 why why WRB cord-015369-72cjogxz 2861 4 the the DT cord-015369-72cjogxz 2861 5 visual visual JJ cord-015369-72cjogxz 2861 6 large large JJ cord-015369-72cjogxz 2861 7 intestine intestine NN cord-015369-72cjogxz 2861 8 hypoplasia hypoplasia NN cord-015369-72cjogxz 2861 9 or or CC cord-015369-72cjogxz 2861 10 keeping keeping NN cord-015369-72cjogxz 2861 11 of of IN cord-015369-72cjogxz 2861 12 partial partial JJ cord-015369-72cjogxz 2861 13 bowel bowel NN cord-015369-72cjogxz 2861 14 obstruction obstruction NN cord-015369-72cjogxz 2861 15 signs sign NNS cord-015369-72cjogxz 2861 16 after after IN cord-015369-72cjogxz 2861 17 the the DT cord-015369-72cjogxz 2861 18 reduction reduction NN cord-015369-72cjogxz 2861 19 of of IN cord-015369-72cjogxz 2861 20 necrotic necrotic JJ cord-015369-72cjogxz 2861 21 enterocolitis enterocolitis NN cord-015369-72cjogxz 2861 22 effects effect NNS cord-015369-72cjogxz 2861 23 of of IN cord-015369-72cjogxz 2861 24 newborns newborn NNS cord-015369-72cjogxz 2861 25 must must MD cord-015369-72cjogxz 2861 26 be be VB cord-015369-72cjogxz 2861 27 the the DT cord-015369-72cjogxz 2861 28 reason reason NN cord-015369-72cjogxz 2861 29 for for IN cord-015369-72cjogxz 2861 30 the the DT cord-015369-72cjogxz 2861 31 large large JJ cord-015369-72cjogxz 2861 32 intestine intestine NN cord-015369-72cjogxz 2861 33 biopsy biopsy NN cord-015369-72cjogxz 2861 34 and and CC cord-015369-72cjogxz 2861 35 histochemical histochemical JJ cord-015369-72cjogxz 2861 36 investigation investigation NN cord-015369-72cjogxz 2861 37 of of IN cord-015369-72cjogxz 2861 38 biopsy biopsy NNP cord-015369-72cjogxz 2861 39 material material NN cord-015369-72cjogxz 2861 40 for for IN cord-015369-72cjogxz 2861 41 this this DT cord-015369-72cjogxz 2861 42 group group NN cord-015369-72cjogxz 2861 43 of of IN cord-015369-72cjogxz 2861 44 patients patient NNS cord-015369-72cjogxz 2861 45 . . . cord-015369-72cjogxz 2862 1 Zur Zur NNP cord-015369-72cjogxz 2862 2 angeborenen angeborenen NNP cord-015369-72cjogxz 2862 3 Dilatation Dilatation NNP cord-015369-72cjogxz 2862 4 von von NNP cord-015369-72cjogxz 2863 1 Intestinalsegmentenein Intestinalsegmentenein NNP cord-015369-72cjogxz 2863 2 Beitrag Beitrag NNP cord-015369-72cjogxz 2863 3 zu zu NNP cord-015369-72cjogxz 2863 4 einem einem NNP cord-015369-72cjogxz 2863 5 seltenen seltenen NNP cord-015369-72cjogxz 2863 6 Krankheitsbild Krankheitsbild NNP cord-015369-72cjogxz 2863 7 Accidental accidental JJ cord-015369-72cjogxz 2863 8 ingestion ingestion NN cord-015369-72cjogxz 2863 9 of of IN cord-015369-72cjogxz 2863 10 foreign foreign JJ cord-015369-72cjogxz 2863 11 bodies body NNS cord-015369-72cjogxz 2863 12 is be VBZ cord-015369-72cjogxz 2863 13 a a DT cord-015369-72cjogxz 2863 14 common common JJ cord-015369-72cjogxz 2863 15 problem problem NN cord-015369-72cjogxz 2863 16 in in IN cord-015369-72cjogxz 2863 17 infants infant NNS cord-015369-72cjogxz 2863 18 and and CC cord-015369-72cjogxz 2863 19 childhood childhood NN cord-015369-72cjogxz 2863 20 , , , cord-015369-72cjogxz 2863 21 but but CC cord-015369-72cjogxz 2863 22 ingestion ingestion NN cord-015369-72cjogxz 2863 23 of of IN cord-015369-72cjogxz 2863 24 magnetic magnetic JJ cord-015369-72cjogxz 2863 25 construction construction NN cord-015369-72cjogxz 2863 26 toys toy NNS cord-015369-72cjogxz 2863 27 is be VBZ cord-015369-72cjogxz 2863 28 very very RB cord-015369-72cjogxz 2863 29 rare rare JJ cord-015369-72cjogxz 2863 30 . . . cord-015369-72cjogxz 2864 1 When when WRB cord-015369-72cjogxz 2864 2 multiple multiple JJ cord-015369-72cjogxz 2864 3 parts part NNS cord-015369-72cjogxz 2864 4 of of IN cord-015369-72cjogxz 2864 5 these these DT cord-015369-72cjogxz 2864 6 magnetic magnetic JJ cord-015369-72cjogxz 2864 7 construction construction NN cord-015369-72cjogxz 2864 8 toys toy NNS cord-015369-72cjogxz 2864 9 are be VBP cord-015369-72cjogxz 2864 10 ingested ingest VBN cord-015369-72cjogxz 2864 11 , , , cord-015369-72cjogxz 2864 12 they -PRON- PRP cord-015369-72cjogxz 2864 13 may may MD cord-015369-72cjogxz 2864 14 attract attract VB cord-015369-72cjogxz 2864 15 each each DT cord-015369-72cjogxz 2864 16 other other JJ cord-015369-72cjogxz 2864 17 through through IN cord-015369-72cjogxz 2864 18 the the DT cord-015369-72cjogxz 2864 19 intestinal intestinal JJ cord-015369-72cjogxz 2864 20 walls wall NNS cord-015369-72cjogxz 2864 21 , , , cord-015369-72cjogxz 2864 22 causing cause VBG cord-015369-72cjogxz 2864 23 pressure pressure NN cord-015369-72cjogxz 2864 24 necrosis necrosis NN cord-015369-72cjogxz 2864 25 , , , cord-015369-72cjogxz 2864 26 perforation perforation NN cord-015369-72cjogxz 2864 27 , , , cord-015369-72cjogxz 2864 28 fistula fistula NN cord-015369-72cjogxz 2864 29 formation formation NN cord-015369-72cjogxz 2864 30 or or CC cord-015369-72cjogxz 2864 31 intestinal intestinal JJ cord-015369-72cjogxz 2864 32 obstruction obstruction NN cord-015369-72cjogxz 2864 33 . . . cord-015369-72cjogxz 2865 1 A a DT cord-015369-72cjogxz 2865 2 20-month 20-month JJ cord-015369-72cjogxz 2865 3 old old JJ cord-015369-72cjogxz 2865 4 boy boy NN cord-015369-72cjogxz 2865 5 presented present VBN cord-015369-72cjogxz 2865 6 with with IN cord-015369-72cjogxz 2865 7 a a DT cord-015369-72cjogxz 2865 8 three three CD cord-015369-72cjogxz 2865 9 day day NN cord-015369-72cjogxz 2865 10 history history NN cord-015369-72cjogxz 2865 11 of of IN cord-015369-72cjogxz 2865 12 abdominal abdominal JJ cord-015369-72cjogxz 2865 13 pain pain NN cord-015369-72cjogxz 2865 14 and and CC cord-015369-72cjogxz 2865 15 bilious bilious JJ cord-015369-72cjogxz 2865 16 vomiting vomiting NN cord-015369-72cjogxz 2865 17 . . . cord-015369-72cjogxz 2866 1 Physical physical JJ cord-015369-72cjogxz 2866 2 examination examination NN cord-015369-72cjogxz 2866 3 revealed reveal VBD cord-015369-72cjogxz 2866 4 a a DT cord-015369-72cjogxz 2866 5 slighted slighted JJ cord-015369-72cjogxz 2866 6 distended distended JJ cord-015369-72cjogxz 2866 7 abdomen abdoman NNS cord-015369-72cjogxz 2866 8 . . . cord-015369-72cjogxz 2867 1 The the DT cord-015369-72cjogxz 2867 2 white white JJ cord-015369-72cjogxz 2867 3 blood blood NN cord-015369-72cjogxz 2867 4 cell cell NN cord-015369-72cjogxz 2867 5 count count NN cord-015369-72cjogxz 2867 6 was be VBD cord-015369-72cjogxz 2867 7 normal normal JJ cord-015369-72cjogxz 2867 8 , , , cord-015369-72cjogxz 2867 9 but but CC cord-015369-72cjogxz 2867 10 the the DT cord-015369-72cjogxz 2867 11 C C NNP cord-015369-72cjogxz 2867 12 - - HYPH cord-015369-72cjogxz 2867 13 reactive reactive JJ cord-015369-72cjogxz 2867 14 protein protein NN cord-015369-72cjogxz 2867 15 was be VBD cord-015369-72cjogxz 2867 16 elevated elevate VBN cord-015369-72cjogxz 2867 17 . . . cord-015369-72cjogxz 2868 1 Ultrasound ultrasound NN cord-015369-72cjogxz 2868 2 and and CC cord-015369-72cjogxz 2868 3 X x NN cord-015369-72cjogxz 2868 4 - - NN cord-015369-72cjogxz 2868 5 ray ray NN cord-015369-72cjogxz 2868 6 of of IN cord-015369-72cjogxz 2868 7 the the DT cord-015369-72cjogxz 2868 8 abdomen abdomen NN cord-015369-72cjogxz 2868 9 showed show VBD cord-015369-72cjogxz 2868 10 a a DT cord-015369-72cjogxz 2868 11 distended distended JJ cord-015369-72cjogxz 2868 12 bowel bowel NN cord-015369-72cjogxz 2868 13 loop loop NN cord-015369-72cjogxz 2868 14 in in IN cord-015369-72cjogxz 2868 15 the the DT cord-015369-72cjogxz 2868 16 right right JJ cord-015369-72cjogxz 2868 17 upper upper NN cord-015369-72cjogxz 2868 18 , , , cord-015369-72cjogxz 2868 19 a a DT cord-015369-72cjogxz 2868 20 moderate moderate JJ cord-015369-72cjogxz 2868 21 amount amount NN cord-015369-72cjogxz 2868 22 of of IN cord-015369-72cjogxz 2868 23 free free JJ cord-015369-72cjogxz 2868 24 intraperitoneal intraperitoneal JJ cord-015369-72cjogxz 2868 25 liquid liquid NN cord-015369-72cjogxz 2868 26 and and CC cord-015369-72cjogxz 2868 27 four four CD cord-015369-72cjogxz 2868 28 foreign foreign JJ cord-015369-72cjogxz 2868 29 bodies body NNS cord-015369-72cjogxz 2868 30 . . . cord-015369-72cjogxz 2869 1 Emergency emergency NN cord-015369-72cjogxz 2869 2 laparotomy laparotomy NN cord-015369-72cjogxz 2869 3 was be VBD cord-015369-72cjogxz 2869 4 performed perform VBN cord-015369-72cjogxz 2869 5 and and CC cord-015369-72cjogxz 2869 6 two two CD cord-015369-72cjogxz 2869 7 perforations perforation NNS cord-015369-72cjogxz 2869 8 in in IN cord-015369-72cjogxz 2869 9 the the DT cord-015369-72cjogxz 2869 10 ileum ileum NN cord-015369-72cjogxz 2869 11 could could MD cord-015369-72cjogxz 2869 12 be be VB cord-015369-72cjogxz 2869 13 detected detect VBN cord-015369-72cjogxz 2869 14 . . . cord-015369-72cjogxz 2870 1 The the DT cord-015369-72cjogxz 2870 2 perforation perforation NN cord-015369-72cjogxz 2870 3 was be VBD cord-015369-72cjogxz 2870 4 caused cause VBN cord-015369-72cjogxz 2870 5 by by IN cord-015369-72cjogxz 2870 6 a a DT cord-015369-72cjogxz 2870 7 magnetic magnetic JJ cord-015369-72cjogxz 2870 8 construction construction NN cord-015369-72cjogxz 2870 9 toy toy NN cord-015369-72cjogxz 2870 10 and and CC cord-015369-72cjogxz 2870 11 two two CD cord-015369-72cjogxz 2870 12 iron iron NN cord-015369-72cjogxz 2870 13 globes globe NNS cord-015369-72cjogxz 2870 14 . . . cord-015369-72cjogxz 2871 1 The the DT cord-015369-72cjogxz 2871 2 fourth fourth JJ cord-015369-72cjogxz 2871 3 foreign foreign JJ cord-015369-72cjogxz 2871 4 body body NN cord-015369-72cjogxz 2871 5 was be VBD cord-015369-72cjogxz 2871 6 a a DT cord-015369-72cjogxz 2871 7 glass glass NN cord-015369-72cjogxz 2871 8 marble marble NN cord-015369-72cjogxz 2871 9 . . . cord-015369-72cjogxz 2872 1 The the DT cord-015369-72cjogxz 2872 2 foreign foreign JJ cord-015369-72cjogxz 2872 3 bodies body NNS cord-015369-72cjogxz 2872 4 were be VBD cord-015369-72cjogxz 2872 5 removed remove VBN cord-015369-72cjogxz 2872 6 , , , cord-015369-72cjogxz 2872 7 both both DT cord-015369-72cjogxz 2872 8 perforations perforation NNS cord-015369-72cjogxz 2872 9 were be VBD cord-015369-72cjogxz 2872 10 primary primary JJ cord-015369-72cjogxz 2872 11 sutured suture VBN cord-015369-72cjogxz 2872 12 . . . cord-015369-72cjogxz 2873 1 The the DT cord-015369-72cjogxz 2873 2 child child NN cord-015369-72cjogxz 2873 3 was be VBD cord-015369-72cjogxz 2873 4 discharged discharge VBN cord-015369-72cjogxz 2873 5 on on IN cord-015369-72cjogxz 2873 6 postoperative postoperative JJ cord-015369-72cjogxz 2873 7 day day NN cord-015369-72cjogxz 2873 8 10 10 CD cord-015369-72cjogxz 2873 9 after after IN cord-015369-72cjogxz 2873 10 an an DT cord-015369-72cjogxz 2873 11 uneventful uneventful JJ cord-015369-72cjogxz 2873 12 recovery recovery NN cord-015369-72cjogxz 2873 13 . . . cord-015369-72cjogxz 2874 1 Parents parent NNS cord-015369-72cjogxz 2874 2 should should MD cord-015369-72cjogxz 2874 3 be be VB cord-015369-72cjogxz 2874 4 warned warn VBN cord-015369-72cjogxz 2874 5 against against IN cord-015369-72cjogxz 2874 6 the the DT cord-015369-72cjogxz 2874 7 potential potential JJ cord-015369-72cjogxz 2874 8 dangers danger NNS cord-015369-72cjogxz 2874 9 of of IN cord-015369-72cjogxz 2874 10 children child NNS cord-015369-72cjogxz 2874 11 's 's POS cord-015369-72cjogxz 2874 12 constructions construction NNS cord-015369-72cjogxz 2874 13 toys toy NNS cord-015369-72cjogxz 2874 14 that that WDT cord-015369-72cjogxz 2874 15 contain contain VBP cord-015369-72cjogxz 2874 16 these these DT cord-015369-72cjogxz 2874 17 kinds kind NNS cord-015369-72cjogxz 2874 18 of of IN cord-015369-72cjogxz 2874 19 magnets magnet NNS cord-015369-72cjogxz 2874 20 . . . cord-015369-72cjogxz 2875 1 Interdisziplinärer Interdisziplinärer NNP cord-015369-72cjogxz 2875 2 Zusammenarbeit Zusammenarbeit NNP cord-015369-72cjogxz 2875 3 bei bei NNP cord-015369-72cjogxz 2875 4 Kindern Kindern NNP cord-015369-72cjogxz 2875 5 mit mit VBP cord-015369-72cjogxz 2875 6 anorektalen anorektalen NNP cord-015369-72cjogxz 2875 7 Malformationen Malformationen NNP cord-015369-72cjogxz 2875 8 -Erfahrungen -Erfahrungen NNP cord-015369-72cjogxz 2875 9 des des XX cord-015369-72cjogxz 2875 10 colorektalen colorektalen NNP cord-015369-72cjogxz 2875 11 Teams Teams NNPS cord-015369-72cjogxz 2875 12 in in IN cord-015369-72cjogxz 2875 13 Linz Linz NNP cord-015369-72cjogxz 2875 14 Landes- Landes- NNP cord-015369-72cjogxz 2875 15 , , , cord-015369-72cjogxz 2875 16 Frauen Frauen NNP cord-015369-72cjogxz 2875 17 - - HYPH cord-015369-72cjogxz 2875 18 und und NNP cord-015369-72cjogxz 2875 19 Kinderklinik Kinderklinik NNP cord-015369-72cjogxz 2875 20 , , , cord-015369-72cjogxz 2875 21 Linz Linz NNP cord-015369-72cjogxz 2875 22 , , , cord-015369-72cjogxz 2875 23 Austria Austria NNP cord-015369-72cjogxz 2875 24 Bei Bei NNP cord-015369-72cjogxz 2875 25 Kindern Kindern NNP cord-015369-72cjogxz 2876 1 mit mit NNP cord-015369-72cjogxz 2876 2 anorektalen anorektalen NNP cord-015369-72cjogxz 2876 3 Malformationen Malformationen NNP cord-015369-72cjogxz 2876 4 besteht besteht NNP cord-015369-72cjogxz 2876 5 eine eine NNP cord-015369-72cjogxz 2877 1 sehr sehr NNP cord-015369-72cjogxz 2877 2 hohe hohe NNP cord-015369-72cjogxz 2877 3 Wahrscheinlichkeit Wahrscheinlichkeit NNP cord-015369-72cjogxz 2877 4 , , , cord-015369-72cjogxz 2877 5 auch auch NNP cord-015369-72cjogxz 2877 6 an an DT cord-015369-72cjogxz 2877 7 anderen anderen NN cord-015369-72cjogxz 2877 8 Stellen Stellen NNP cord-015369-72cjogxz 2877 9 Fehlbildungen Fehlbildungen NNP cord-015369-72cjogxz 2877 10 aufzuweisen aufzuweisen NNP cord-015369-72cjogxz 2877 11 . . . cord-015369-72cjogxz 2878 1 Dies die VBZ cord-015369-72cjogxz 2878 2 erfordert erfordert NNP cord-015369-72cjogxz 2878 3 nicht nicht NNP cord-015369-72cjogxz 2878 4 nur nur NNP cord-015369-72cjogxz 2878 5 bei bei NNP cord-015369-72cjogxz 2878 6 der der NNP cord-015369-72cjogxz 2878 7 Abklärung Abklärung NNP cord-015369-72cjogxz 2878 8 sondern sondern NNP cord-015369-72cjogxz 2878 9 auch auch NNP cord-015369-72cjogxz 2878 10 bei bei NNP cord-015369-72cjogxz 2878 11 der der NNP cord-015369-72cjogxz 2878 12 Behandlung Behandlung NNP cord-015369-72cjogxz 2878 13 und und IN cord-015369-72cjogxz 2878 14 Nachbetreuung Nachbetreuung NNP cord-015369-72cjogxz 2878 15 eine eine NNP cord-015369-72cjogxz 2878 16 enge enge NNP cord-015369-72cjogxz 2878 17 Zusammenarbeit Zusammenarbeit NNP cord-015369-72cjogxz 2878 18 mit mit NNP cord-015369-72cjogxz 2878 19 anderen anderen NNP cord-015369-72cjogxz 2878 20 Fachabteilungen Fachabteilungen NNP cord-015369-72cjogxz 2878 21 und und NNP cord-015369-72cjogxz 2878 22 der der NNP cord-015369-72cjogxz 2878 23 Pflege Pflege NNP cord-015369-72cjogxz 2878 24 . . . cord-015369-72cjogxz 2879 1 An an DT cord-015369-72cjogxz 2879 2 unserer unserer JJ cord-015369-72cjogxz 2879 3 kinderchirurgischen kinderchirurgischen NNP cord-015369-72cjogxz 2879 4 Abteilung Abteilung NNP cord-015369-72cjogxz 2879 5 in in IN cord-015369-72cjogxz 2879 6 der der NNP cord-015369-72cjogxz 2879 7 Landes- Landes- NNP cord-015369-72cjogxz 2879 8 , , , cord-015369-72cjogxz 2880 1 Frauen Frauen NNP cord-015369-72cjogxz 2880 2 - - HYPH cord-015369-72cjogxz 2880 3 und und NNP cord-015369-72cjogxz 2880 4 Kinderklinik Kinderklinik NNP cord-015369-72cjogxz 2880 5 hat hat NN cord-015369-72cjogxz 2880 6 sich sich NN cord-015369-72cjogxz 2880 7 ein ein NNP cord-015369-72cjogxz 2880 8 colorektales colorektale NNS cord-015369-72cjogxz 2881 1 Team Team NNP cord-015369-72cjogxz 2881 2 aus aus NNP cord-015369-72cjogxz 2881 3 Ä ä NN cord-015369-72cjogxz 2881 4 rzten rzten NNS cord-015369-72cjogxz 2881 5 und und IN cord-015369-72cjogxz 2881 6 Pflegepersonen Pflegepersonen NNP cord-015369-72cjogxz 2881 7 gebildet gebildet NNP cord-015369-72cjogxz 2881 8 , , , cord-015369-72cjogxz 2881 9 das das NNP cord-015369-72cjogxz 2881 10 zum zum NNP cord-015369-72cjogxz 2881 11 einen einen NNP cord-015369-72cjogxz 2881 12 die die VB cord-015369-72cjogxz 2881 13 anorektalen anorektalen NNP cord-015369-72cjogxz 2881 14 Malformationen Malformationen NNP cord-015369-72cjogxz 2881 15 der der NNP cord-015369-72cjogxz 2881 16 Kinder Kinder NNP cord-015369-72cjogxz 2881 17 operiert operiert NNP cord-015369-72cjogxz 2882 1 und und NNP cord-015369-72cjogxz 2882 2 nachbetreut nachbetreut NNP cord-015369-72cjogxz 2882 3 , , , cord-015369-72cjogxz 2882 4 zum zum NNP cord-015369-72cjogxz 2882 5 anderen anderen NNP cord-015369-72cjogxz 2882 6 als als NN cord-015369-72cjogxz 2882 7 interdisziplinäre interdisziplinäre NN cord-015369-72cjogxz 2882 8 Drehscheibe Drehscheibe NNP cord-015369-72cjogxz 2882 9 zu zu NNP cord-015369-72cjogxz 2882 10 anderen anderen NNP cord-015369-72cjogxz 2882 11 Abteilungen Abteilungen NNP cord-015369-72cjogxz 2882 12 fungiert fungiert NN cord-015369-72cjogxz 2882 13 . . . cord-015369-72cjogxz 2883 1 Mehr Mehr NNP cord-015369-72cjogxz 2883 2 Bereits Bereits NNP cord-015369-72cjogxz 2883 3 bei bei NNP cord-015369-72cjogxz 2883 4 der der NNP cord-015369-72cjogxz 2883 5 Abklärung Abklärung NNP cord-015369-72cjogxz 2883 6 der der NNP cord-015369-72cjogxz 2883 7 Patienten Patienten NNP cord-015369-72cjogxz 2883 8 mittels mittels NNPS cord-015369-72cjogxz 2883 9 Endoskopie Endoskopie NNP cord-015369-72cjogxz 2883 10 spielt spielt NNP cord-015369-72cjogxz 2883 11 der der NNP cord-015369-72cjogxz 2883 12 Kinderchirurg Kinderchirurg NNP cord-015369-72cjogxz 2883 13 eine eine NNP cord-015369-72cjogxz 2883 14 wesentliche wesentliche NN cord-015369-72cjogxz 2883 15 Rolle Rolle NNP cord-015369-72cjogxz 2883 16 . . . cord-015369-72cjogxz 2884 1 Bewährt Bewährt NNP cord-015369-72cjogxz 2884 2 hat hat NN cord-015369-72cjogxz 2884 3 sich sich XX cord-015369-72cjogxz 2884 4 die die VB cord-015369-72cjogxz 2885 1 Anwesenheit Anwesenheit NNP cord-015369-72cjogxz 2885 2 des des FW cord-015369-72cjogxz 2885 3 Gastroenterologen Gastroenterologen NNP cord-015369-72cjogxz 2885 4 während während NNP cord-015369-72cjogxz 2885 5 der der NNP cord-015369-72cjogxz 2885 6 Endoskopie Endoskopie NNP cord-015369-72cjogxz 2885 7 . . . cord-015369-72cjogxz 2886 1 Sind sind UH cord-015369-72cjogxz 2886 2 die die VBP cord-015369-72cjogxz 2886 3 Indikationen Indikationen NNP cord-015369-72cjogxz 2886 4 zur zur NNP cord-015369-72cjogxz 2886 5 operativen operativen NNP cord-015369-72cjogxz 2886 6 Intervention Intervention NNP cord-015369-72cjogxz 2886 7 beim beim NNP cord-015369-72cjogxz 2886 8 Mb Mb NNP cord-015369-72cjogxz 2886 9 . . . cord-015369-72cjogxz 2887 1 Crohn Crohn NNP cord-015369-72cjogxz 2887 2 klar klar NNP cord-015369-72cjogxz 2887 3 , , , cord-015369-72cjogxz 2887 4 ist ist NNP cord-015369-72cjogxz 2887 5 bei bei NNP cord-015369-72cjogxz 2887 6 der der NNP cord-015369-72cjogxz 2887 7 Colitis colitis NN cord-015369-72cjogxz 2888 1 ulcerosa ulcerosa NNP cord-015369-72cjogxz 2888 2 nur nur NNP cord-015369-72cjogxz 2888 3 die die VBP cord-015369-72cjogxz 2888 4 Behandlung Behandlung NNP cord-015369-72cjogxz 2888 5 des des FW cord-015369-72cjogxz 2888 6 toxischen toxischen NNP cord-015369-72cjogxz 2888 7 Megacolons Megacolons NNP cord-015369-72cjogxz 2888 8 eindeutig eindeutig NNP cord-015369-72cjogxz 2888 9 . . . cord-015369-72cjogxz 2889 1 I -PRON- PRP cord-015369-72cjogxz 2889 2 m be VBP cord-015369-72cjogxz 2889 3 Allgemeinen Allgemeinen NNP cord-015369-72cjogxz 2889 4 wird wird NNP cord-015369-72cjogxz 2889 5 der der NNP cord-015369-72cjogxz 2889 6 Chirurg Chirurg NNP cord-015369-72cjogxz 2889 7 erst erst NNP cord-015369-72cjogxz 2889 8 am be VBP cord-015369-72cjogxz 2889 9 Ende Ende NNP cord-015369-72cjogxz 2889 10 der der NNP cord-015369-72cjogxz 2889 11 konservativen konservativen NNP cord-015369-72cjogxz 2889 12 Therapie Therapie NNP cord-015369-72cjogxz 2889 13 beigezogen beigezogen NNP cord-015369-72cjogxz 2889 14 , , , cord-015369-72cjogxz 2889 15 wenn wenn NNP cord-015369-72cjogxz 2889 16 sich sich NNP cord-015369-72cjogxz 2889 17 der der NNP cord-015369-72cjogxz 2889 18 Patient Patient NNP cord-015369-72cjogxz 2889 19 bereits bereits NNP cord-015369-72cjogxz 2889 20 in in IN cord-015369-72cjogxz 2889 21 schlechtem schlechtem NNP cord-015369-72cjogxz 2890 1 Allgemeinzustand Allgemeinzustand NNP cord-015369-72cjogxz 2890 2 befindet befindet NNP cord-015369-72cjogxz 2890 3 oder oder NNP cord-015369-72cjogxz 2890 4 Komplikationen Komplikationen NNP cord-015369-72cjogxz 2890 5 von von NNP cord-015369-72cjogxz 2890 6 Seiten Seiten NNP cord-015369-72cjogxz 2891 1 der der NNP cord-015369-72cjogxz 2892 1 nicht nicht NNP cord-015369-72cjogxz 2892 2 ganz ganz NNP cord-015369-72cjogxz 2892 3 harmlosen harmlosen NNP cord-015369-72cjogxz 2893 1 Medikation Medikation NNP cord-015369-72cjogxz 2893 2 eingetreten eingetreten NNP cord-015369-72cjogxz 2894 1 sind sind UH cord-015369-72cjogxz 2894 2 . . . cord-015369-72cjogxz 2895 1 Anhand Anhand NNP cord-015369-72cjogxz 2895 2 eines eine NNS cord-015369-72cjogxz 2896 1 13-jährigen 13-jährigen CD cord-015369-72cjogxz 2897 1 Mädchens Mädchens NNP cord-015369-72cjogxz 2897 2 mit mit NNP cord-015369-72cjogxz 2897 3 ausgeschöpfter ausgeschöpfter NN cord-015369-72cjogxz 2897 4 Therapie Therapie NNP cord-015369-72cjogxz 2897 5 ( ( -LRB- cord-015369-72cjogxz 2897 6 Sandimun Sandimun NNP cord-015369-72cjogxz 2897 7 , , , cord-015369-72cjogxz 2897 8 Imurek Imurek NNP cord-015369-72cjogxz 2897 9 und und IN cord-015369-72cjogxz 2897 10 Prednisolon Prednisolon NNP cord-015369-72cjogxz 2897 11 ) ) -RRB- cord-015369-72cjogxz 2897 12 möchte möchte NNP cord-015369-72cjogxz 2897 13 ich ich NNP cord-015369-72cjogxz 2897 14 unser unser NNP cord-015369-72cjogxz 2897 15 Vorgehen Vorgehen NNP cord-015369-72cjogxz 2897 16 darstellen darstellen NNS cord-015369-72cjogxz 2897 17 . . . cord-015369-72cjogxz 2898 1 Trotz Trotz NNP cord-015369-72cjogxz 2898 2 maximaler maximaler NNP cord-015369-72cjogxz 2898 3 konservativer konservativer NNP cord-015369-72cjogxz 2898 4 Therapie Therapie NNP cord-015369-72cjogxz 2898 5 konnten konnten NNP cord-015369-72cjogxz 2898 6 die die VBP cord-015369-72cjogxz 2899 1 Blutungen Blutungen NNP cord-015369-72cjogxz 2899 2 nicht nicht NNP cord-015369-72cjogxz 2899 3 gestoppt gestoppt NNP cord-015369-72cjogxz 2899 4 werden werden NNP cord-015369-72cjogxz 2899 5 . . . cord-015369-72cjogxz 2900 1 Wegen Wegen NNP cord-015369-72cjogxz 2900 2 Grundlagen Grundlagen NNP cord-015369-72cjogxz 2900 3 . . . cord-015369-72cjogxz 2901 1 Die die VB cord-015369-72cjogxz 2902 1 Pilonidalsinus Pilonidalsinus NNP cord-015369-72cjogxz 2902 2 - - HYPH cord-015369-72cjogxz 2902 3 Erkrankung Erkrankung NNP cord-015369-72cjogxz 2902 4 ist ist NN cord-015369-72cjogxz 2902 5 eine eine NNP cord-015369-72cjogxz 2902 6 in in IN cord-015369-72cjogxz 2902 7 der der NNP cord-015369-72cjogxz 2902 8 Rima Rima NNP cord-015369-72cjogxz 2902 9 ani ani NNP cord-015369-72cjogxz 2902 10 lokalisierte lokalisierte NNP cord-015369-72cjogxz 2902 11 granulomätöse granulomätöse NNP cord-015369-72cjogxz 2902 12 Erkrankung Erkrankung NNP cord-015369-72cjogxz 2902 13 , , , cord-015369-72cjogxz 2902 14 verifizierbar verifizierbar NN cord-015369-72cjogxz 2902 15 mittels mittels NNP cord-015369-72cjogxz 2902 16 , , , cord-015369-72cjogxz 2902 17 , , , cord-015369-72cjogxz 2902 18 Blickdiagnose Blickdiagnose NNP cord-015369-72cjogxz 2902 19 ' ' POS cord-015369-72cjogxz 2902 20 ' ' '' cord-015369-72cjogxz 2902 21 . . . cord-015369-72cjogxz 2903 1 Trotz Trotz NNP cord-015369-72cjogxz 2903 2 ihres ihre NNS cord-015369-72cjogxz 2904 1 häufigen häufigen NNP cord-015369-72cjogxz 2905 1 Vorkommens Vorkommens NNP cord-015369-72cjogxz 2905 2 gibt gibt NNP cord-015369-72cjogxz 2906 1 es es XX cord-015369-72cjogxz 2907 1 für für IN cord-015369-72cjogxz 2907 2 die die VBP cord-015369-72cjogxz 2907 3 3 3 CD cord-015369-72cjogxz 2908 1 Erkrankungsstadien Erkrankungsstadien NNP cord-015369-72cjogxz 2908 2 der der NNP cord-015369-72cjogxz 2908 3 Affektion Affektion NNP cord-015369-72cjogxz 2909 1 keine keine NNP cord-015369-72cjogxz 2909 2 allgemein allgemein NNP cord-015369-72cjogxz 2910 1 gültigen gültigen NNP cord-015369-72cjogxz 2910 2 Therapieempfehlungen Therapieempfehlungen NNP cord-015369-72cjogxz 2910 3 . . . cord-015369-72cjogxz 2911 1 Methodik Methodik NNP cord-015369-72cjogxz 2911 2 . . . cord-015369-72cjogxz 2912 1 Während Während NNP cord-015369-72cjogxz 2912 2 der der NNP cord-015369-72cjogxz 2912 3 letzten letzten NNP cord-015369-72cjogxz 2913 1 12 12 CD cord-015369-72cjogxz 2913 2 Jahre Jahre NNP cord-015369-72cjogxz 2913 3 wurden wurden VBD cord-015369-72cjogxz 2913 4 49 49 CD cord-015369-72cjogxz 2913 5 Kinder/ Kinder/ NNP cord-015369-72cjogxz 2913 6 Jugendliche Jugendliche NNP cord-015369-72cjogxz 2913 7 ( ( -LRB- cord-015369-72cjogxz 2913 8 10 10 CD cord-015369-72cjogxz 2913 9 Mädchen Mädchen NNP cord-015369-72cjogxz 2913 10 , , , cord-015369-72cjogxz 2913 11 39 39 CD cord-015369-72cjogxz 2913 12 männliche männliche NN cord-015369-72cjogxz 2913 13 Kinder Kinder NNP cord-015369-72cjogxz 2913 14 / / SYM cord-015369-72cjogxz 2913 15 Jugendliche Jugendliche NNP cord-015369-72cjogxz 2914 1 ( ( -LRB- cord-015369-72cjogxz 2914 2 Alter alter VB cord-015369-72cjogxz 2914 3 zwischen zwischen NNP cord-015369-72cjogxz 2914 4 12 12 CD cord-015369-72cjogxz 2914 5 und und CD cord-015369-72cjogxz 2914 6 18 18 CD cord-015369-72cjogxz 2914 7 Jahren Jahren NNP cord-015369-72cjogxz 2914 8 ) ) -RRB- cord-015369-72cjogxz 2914 9 ) ) -RRB- cord-015369-72cjogxz 2915 1 wegen wegen NNP cord-015369-72cjogxz 2915 2 einer einer NNP cord-015369-72cjogxz 2915 3 Pilonidalsinus Pilonidalsinus NNP cord-015369-72cjogxz 2915 4 - - HYPH cord-015369-72cjogxz 2915 5 Erkrankung Erkrankung NNP cord-015369-72cjogxz 2915 6 behandelt behandelt NNP cord-015369-72cjogxz 2915 7 . . . cord-015369-72cjogxz 2916 1 3 3 LS cord-015369-72cjogxz 2916 2 waren waren NNP cord-015369-72cjogxz 2916 3 asymptomatisch asymptomatisch NNP cord-015369-72cjogxz 2916 4 , , , cord-015369-72cjogxz 2916 5 der der NNP cord-015369-72cjogxz 2916 6 Prozess Prozess NNP cord-015369-72cjogxz 2916 7 wurde wurde NNP cord-015369-72cjogxz 2916 8 exzidiert exzidiert NNP cord-015369-72cjogxz 2916 9 und und NNP cord-015369-72cjogxz 2916 10 der der NNP cord-015369-72cjogxz 2916 11 Defekt Defekt NNP cord-015369-72cjogxz 2916 12 linear linear JJ cord-015369-72cjogxz 2916 13 verschlossen verschlossen NN cord-015369-72cjogxz 2916 14 . . . cord-015369-72cjogxz 2917 1 8 8 CD cord-015369-72cjogxz 2918 1 hatten hatten NNP cord-015369-72cjogxz 2919 1 ein ein NNP cord-015369-72cjogxz 2919 2 chronisch chronisch NNP cord-015369-72cjogxz 2919 3 - - HYPH cord-015369-72cjogxz 2919 4 entzündliches entzündliche NNS cord-015369-72cjogxz 2920 1 Geschehen geschehen NN cord-015369-72cjogxz 2920 2 : : : cord-015369-72cjogxz 2920 3 nach nach NNP cord-015369-72cjogxz 2920 4 Exzision Exzision NNP cord-015369-72cjogxz 2920 5 des des FW cord-015369-72cjogxz 2920 6 Herdes Herdes NNP cord-015369-72cjogxz 2920 7 wurde wurde NNP cord-015369-72cjogxz 2920 8 bei bei NNP cord-015369-72cjogxz 2920 9 einem einem NNP cord-015369-72cjogxz 2920 10 eine eine NNP cord-015369-72cjogxz 2920 11 Limberg Limberg NNP cord-015369-72cjogxz 2920 12 - - HYPH cord-015369-72cjogxz 2920 13 Lappendeckung Lappendeckung NNP cord-015369-72cjogxz 2920 14 , , , cord-015369-72cjogxz 2920 15 bei bei NNP cord-015369-72cjogxz 2920 16 3 3 CD cord-015369-72cjogxz 2920 17 eine eine NNP cord-015369-72cjogxz 2920 18 offene offene NNP cord-015369-72cjogxz 2920 19 Wundbehandlung Wundbehandlung NNP cord-015369-72cjogxz 2920 20 und und IN cord-015369-72cjogxz 2920 21 bei bei NNP cord-015369-72cjogxz 2920 22 4 4 CD cord-015369-72cjogxz 2920 23 eine eine NNP cord-015369-72cjogxz 2920 24 Karydakis Karydakis NNP cord-015369-72cjogxz 2920 25 - - HYPH cord-015369-72cjogxz 2920 26 Defektdeckung Defektdeckung NNP cord-015369-72cjogxz 2920 27 durchgeführt durchgeführt NN cord-015369-72cjogxz 2920 28 . . . cord-015369-72cjogxz 2921 1 Die die VB cord-015369-72cjogxz 2921 2 , , , cord-015369-72cjogxz 2921 3 , , , cord-015369-72cjogxz 2921 4 restlichen restlichen NNP cord-015369-72cjogxz 2921 5 ' ' POS cord-015369-72cjogxz 2921 6 ' ' '' cord-015369-72cjogxz 2921 7 38 38 CD cord-015369-72cjogxz 2921 8 Patienten Patienten NNP cord-015369-72cjogxz 2921 9 mit mit NN cord-015369-72cjogxz 2921 10 abszedierendem abszedierendem NN cord-015369-72cjogxz 2921 11 Pilonidalsinus Pilonidalsinus NNP cord-015369-72cjogxz 2921 12 wurden wurden VBD cord-015369-72cjogxz 2921 13 nach nach NNP cord-015369-72cjogxz 2921 14 Abszessinzision Abszessinzision NNP cord-015369-72cjogxz 2921 15 / / SYM cord-015369-72cjogxz 2921 16 exkochleation exkochleation NNP cord-015369-72cjogxz 2921 17 offen offen NNP cord-015369-72cjogxz 2921 18 wundbehandelt wundbehandelt NNPS cord-015369-72cjogxz 2921 19 ; ; : cord-015369-72cjogxz 2922 1 bei bei NNP cord-015369-72cjogxz 2922 2 2 2 CD cord-015369-72cjogxz 2922 3 wurde wurde NNP cord-015369-72cjogxz 2922 4 8 8 CD cord-015369-72cjogxz 2922 5 Tage tage NN cord-015369-72cjogxz 2922 6 später später NNP cord-015369-72cjogxz 2922 7 eine eine NNP cord-015369-72cjogxz 2922 8 Karydakis Karydakis NNP cord-015369-72cjogxz 2922 9 - - HYPH cord-015369-72cjogxz 2922 10 Operation Operation NNP cord-015369-72cjogxz 2922 11 angeschlossen angeschlossen NN cord-015369-72cjogxz 2922 12 . . . cord-015369-72cjogxz 2923 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 2923 2 . . . cord-015369-72cjogxz 2924 1 Bei Bei NNP cord-015369-72cjogxz 2924 2 7 7 CD cord-015369-72cjogxz 2924 3 der der NN cord-015369-72cjogxz 2924 4 10 10 CD cord-015369-72cjogxz 2925 1 Patienten Patienten NNP cord-015369-72cjogxz 2925 2 mit mit NN cord-015369-72cjogxz 2925 3 den den NNP cord-015369-72cjogxz 2925 4 Defektverschlüssen Defektverschlüssen NNP cord-015369-72cjogxz 2925 5 verheilten verheilten NN cord-015369-72cjogxz 2925 6 die die VBP cord-015369-72cjogxz 2925 7 Wunden Wunden NNP cord-015369-72cjogxz 2925 8 innerhalb innerhalb NNP cord-015369-72cjogxz 2925 9 von von NNP cord-015369-72cjogxz 2925 10 2 2 CD cord-015369-72cjogxz 2925 11 Wochen Wochen NNP cord-015369-72cjogxz 2925 12 , , , cord-015369-72cjogxz 2925 13 bei bei NNP cord-015369-72cjogxz 2925 14 den den NNP cord-015369-72cjogxz 2925 15 restlichen restlichen NNP cord-015369-72cjogxz 2925 16 3 3 CD cord-015369-72cjogxz 2926 1 ( ( -LRB- cord-015369-72cjogxz 2926 2 nach nach NNP cord-015369-72cjogxz 2926 3 Karydakis Karydakis NNP cord-015369-72cjogxz 2926 4 - - HYPH cord-015369-72cjogxz 2926 5 Operation Operation NNP cord-015369-72cjogxz 2926 6 ) ) -RRB- cord-015369-72cjogxz 2926 7 innerhalb innerhalb NNP cord-015369-72cjogxz 2926 8 von von NNP cord-015369-72cjogxz 2926 9 4 4 CD cord-015369-72cjogxz 2926 10 Wochen Wochen NNP cord-015369-72cjogxz 2926 11 . . . cord-015369-72cjogxz 2927 1 Die die VB cord-015369-72cjogxz 2927 2 39 39 CD cord-015369-72cjogxz 2927 3 offenen offenen NNP cord-015369-72cjogxz 2927 4 Wundbehandlungen Wundbehandlungen NNP cord-015369-72cjogxz 2927 5 führten führten NNP cord-015369-72cjogxz 2927 6 nach nach NNP cord-015369-72cjogxz 2927 7 einer einer NNP cord-015369-72cjogxz 2927 8 Behandlungsdauer Behandlungsdauer NNP cord-015369-72cjogxz 2927 9 zwischen zwischen NNP cord-015369-72cjogxz 2927 10 8 8 CD cord-015369-72cjogxz 2927 11 1 1 CD cord-015369-72cjogxz 2927 12 / / SYM cord-015369-72cjogxz 2927 13 2 2 CD cord-015369-72cjogxz 2927 14 und und NNP cord-015369-72cjogxz 2928 1 12 12 CD cord-015369-72cjogxz 2928 2 Wochen Wochen NNP cord-015369-72cjogxz 2928 3 zu zu NNP cord-015369-72cjogxz 2928 4 einem einem NNP cord-015369-72cjogxz 2928 5 adäquaten adäquaten NNP cord-015369-72cjogxz 2928 6 Wundverschluss Wundverschluss NNP cord-015369-72cjogxz 2929 1 , , , cord-015369-72cjogxz 2929 2 4 4 CD cord-015369-72cjogxz 2929 3 davon davon NNP cord-015369-72cjogxz 2929 4 entwickelten entwickelten NNP cord-015369-72cjogxz 2929 5 ein ein NNP cord-015369-72cjogxz 2929 6 Sinus Sinus NNP cord-015369-72cjogxz 2929 7 - - HYPH cord-015369-72cjogxz 2929 8 pilonidalis pilonidalis NNP cord-015369-72cjogxz 2929 9 - - HYPH cord-015369-72cjogxz 2929 10 Rezidiv Rezidiv NNP cord-015369-72cjogxz 2929 11 , , , cord-015369-72cjogxz 2929 12 das das NNP cord-015369-72cjogxz 2929 13 exzidiert exzidiert NNP cord-015369-72cjogxz 2929 14 und und IN cord-015369-72cjogxz 2929 15 neuerlich neuerlich NNP cord-015369-72cjogxz 2929 16 offen offen NNP cord-015369-72cjogxz 2929 17 behandelt behandelt NNP cord-015369-72cjogxz 2929 18 wurde wurde NNP cord-015369-72cjogxz 2929 19 . . . cord-015369-72cjogxz 2930 1 Diskussion Diskussion NNP cord-015369-72cjogxz 2930 2 Background Background NNP cord-015369-72cjogxz 2930 3 . . . cord-015369-72cjogxz 2931 1 As as IN cord-015369-72cjogxz 2931 2 the the DT cord-015369-72cjogxz 2931 3 elderly elderly JJ cord-015369-72cjogxz 2931 4 population population NN cord-015369-72cjogxz 2931 5 is be VBZ cord-015369-72cjogxz 2931 6 growing grow VBG cord-015369-72cjogxz 2931 7 , , , cord-015369-72cjogxz 2931 8 the the DT cord-015369-72cjogxz 2931 9 incidence incidence NN cord-015369-72cjogxz 2931 10 of of IN cord-015369-72cjogxz 2931 11 patients patient NNS cord-015369-72cjogxz 2931 12 being be VBG cord-015369-72cjogxz 2931 13 diagnosed diagnose VBN cord-015369-72cjogxz 2931 14 with with IN cord-015369-72cjogxz 2931 15 pancreatic pancreatic JJ cord-015369-72cjogxz 2931 16 cancer cancer NN cord-015369-72cjogxz 2931 17 at at IN cord-015369-72cjogxz 2931 18 the the DT cord-015369-72cjogxz 2931 19 age age NN cord-015369-72cjogxz 2931 20 of of IN cord-015369-72cjogxz 2931 21 70 70 CD cord-015369-72cjogxz 2931 22 and and CC cord-015369-72cjogxz 2931 23 above above RB cord-015369-72cjogxz 2931 24 is be VBZ cord-015369-72cjogxz 2931 25 rising rise VBG cord-015369-72cjogxz 2931 26 . . . cord-015369-72cjogxz 2932 1 Even even RB cord-015369-72cjogxz 2932 2 overall overall JJ cord-015369-72cjogxz 2932 3 morbidity morbidity NN cord-015369-72cjogxz 2932 4 and and CC cord-015369-72cjogxz 2932 5 mortality mortality NN cord-015369-72cjogxz 2932 6 rates rate NNS cord-015369-72cjogxz 2932 7 for for IN cord-015369-72cjogxz 2932 8 pancreatic pancreatic JJ cord-015369-72cjogxz 2932 9 resection resection NN cord-015369-72cjogxz 2932 10 decreased decrease VBD cord-015369-72cjogxz 2932 11 the the DT cord-015369-72cjogxz 2932 12 last last JJ cord-015369-72cjogxz 2932 13 decades decade NNS cord-015369-72cjogxz 2932 14 , , , cord-015369-72cjogxz 2932 15 the the DT cord-015369-72cjogxz 2932 16 indication indication NN cord-015369-72cjogxz 2932 17 of of IN cord-015369-72cjogxz 2932 18 major major JJ cord-015369-72cjogxz 2932 19 pancreatic pancreatic JJ cord-015369-72cjogxz 2932 20 surgery surgery NN cord-015369-72cjogxz 2932 21 in in IN cord-015369-72cjogxz 2932 22 elderly elderly JJ cord-015369-72cjogxz 2932 23 patients patient NNS cord-015369-72cjogxz 2932 24 is be VBZ cord-015369-72cjogxz 2932 25 still still RB cord-015369-72cjogxz 2932 26 discussed discuss VBN cord-015369-72cjogxz 2932 27 controversial controversial JJ cord-015369-72cjogxz 2932 28 . . . cord-015369-72cjogxz 2933 1 Methods method NNS cord-015369-72cjogxz 2933 2 . . . cord-015369-72cjogxz 2934 1 During during IN cord-015369-72cjogxz 2934 2 the the DT cord-015369-72cjogxz 2934 3 last last JJ cord-015369-72cjogxz 2934 4 ten ten CD cord-015369-72cjogxz 2934 5 years year NNS cord-015369-72cjogxz 2934 6 81 81 CD cord-015369-72cjogxz 2934 7 patients patient NNS cord-015369-72cjogxz 2934 8 at at IN cord-015369-72cjogxz 2934 9 the the DT cord-015369-72cjogxz 2934 10 age age NN cord-015369-72cjogxz 2934 11 above above RB cord-015369-72cjogxz 2934 12 70a 70a NNS cord-015369-72cjogxz 2934 13 underwent undergo VBD cord-015369-72cjogxz 2934 14 pancreatic pancreatic JJ cord-015369-72cjogxz 2934 15 resection resection NN cord-015369-72cjogxz 2934 16 for for IN cord-015369-72cjogxz 2934 17 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 2934 18 of of IN cord-015369-72cjogxz 2934 19 the the DT cord-015369-72cjogxz 2934 20 pancreas pancrea NNS cord-015369-72cjogxz 2934 21 at at IN cord-015369-72cjogxz 2934 22 the the DT cord-015369-72cjogxz 2934 23 surgical surgical JJ cord-015369-72cjogxz 2934 24 department department NN cord-015369-72cjogxz 2934 25 of of IN cord-015369-72cjogxz 2934 26 the the DT cord-015369-72cjogxz 2934 27 MUW MUW NNP cord-015369-72cjogxz 2934 28 . . . cord-015369-72cjogxz 2935 1 Perioperative perioperative JJ cord-015369-72cjogxz 2935 2 outcome outcome NN cord-015369-72cjogxz 2935 3 , , , cord-015369-72cjogxz 2935 4 histopathological histopathological JJ cord-015369-72cjogxz 2935 5 findings finding NNS cord-015369-72cjogxz 2935 6 and and CC cord-015369-72cjogxz 2935 7 overall overall JJ cord-015369-72cjogxz 2935 8 survival survival NN cord-015369-72cjogxz 2935 9 was be VBD cord-015369-72cjogxz 2935 10 investigated investigate VBN cord-015369-72cjogxz 2935 11 and and CC cord-015369-72cjogxz 2935 12 compared compare VBN cord-015369-72cjogxz 2935 13 to to IN cord-015369-72cjogxz 2935 14 145 145 CD cord-015369-72cjogxz 2935 15 younger young JJR cord-015369-72cjogxz 2935 16 patients patient NNS cord-015369-72cjogxz 2935 17 . . . cord-015369-72cjogxz 2936 1 Results result NNS cord-015369-72cjogxz 2936 2 . . . cord-015369-72cjogxz 2937 1 Between between IN cord-015369-72cjogxz 2937 2 1998 1998 CD cord-015369-72cjogxz 2937 3 and and CC cord-015369-72cjogxz 2937 4 2008 2008 CD cord-015369-72cjogxz 2937 5 64 64 CD cord-015369-72cjogxz 2937 6 patients patient NNS cord-015369-72cjogxz 2937 7 ( ( -LRB- cord-015369-72cjogxz 2937 8 31 31 CD cord-015369-72cjogxz 2937 9 female female JJ cord-015369-72cjogxz 2937 10 and and CC cord-015369-72cjogxz 2937 11 33male 33male CD cord-015369-72cjogxz 2937 12 ) ) -RRB- cord-015369-72cjogxz 2937 13 at at IN cord-015369-72cjogxz 2937 14 the the DT cord-015369-72cjogxz 2937 15 age age NN cord-015369-72cjogxz 2937 16 of of IN cord-015369-72cjogxz 2937 17 70 70 CD cord-015369-72cjogxz 2937 18 - - SYM cord-015369-72cjogxz 2937 19 79 79 CD cord-015369-72cjogxz 2937 20 and and CC cord-015369-72cjogxz 2937 21 17 17 CD cord-015369-72cjogxz 2937 22 patients patient NNS cord-015369-72cjogxz 2937 23 ( ( -LRB- cord-015369-72cjogxz 2937 24 12 12 CD cord-015369-72cjogxz 2937 25 female female NN cord-015369-72cjogxz 2937 26 and and CC cord-015369-72cjogxz 2937 27 5 5 CD cord-015369-72cjogxz 2937 28 male male JJ cord-015369-72cjogxz 2937 29 ) ) -RRB- cord-015369-72cjogxz 2937 30 80a 80a NNS cord-015369-72cjogxz 2937 31 and and CC cord-015369-72cjogxz 2937 32 older old JJR cord-015369-72cjogxz 2937 33 , , , cord-015369-72cjogxz 2937 34 had have VBD cord-015369-72cjogxz 2937 35 pancreatic pancreatic JJ cord-015369-72cjogxz 2937 36 resection resection NN cord-015369-72cjogxz 2937 37 with with IN cord-015369-72cjogxz 2937 38 curative curative JJ cord-015369-72cjogxz 2937 39 intent intent NN cord-015369-72cjogxz 2937 40 . . . cord-015369-72cjogxz 2938 1 The the DT cord-015369-72cjogxz 2938 2 pancreatic pancreatic JJ cord-015369-72cjogxz 2938 3 head head NN cord-015369-72cjogxz 2938 4 was be VBD cord-015369-72cjogxz 2938 5 the the DT cord-015369-72cjogxz 2938 6 predominant predominant JJ cord-015369-72cjogxz 2938 7 location location NN cord-015369-72cjogxz 2938 8 within within IN cord-015369-72cjogxz 2938 9 both both DT cord-015369-72cjogxz 2938 10 groups group NNS cord-015369-72cjogxz 2938 11 . . . cord-015369-72cjogxz 2939 1 84 84 CD cord-015369-72cjogxz 2939 2 % % NN cord-015369-72cjogxz 2939 3 of of IN cord-015369-72cjogxz 2939 4 the the DT cord-015369-72cjogxz 2939 5 elderly elderly JJ cord-015369-72cjogxz 2939 6 patients patient NNS cord-015369-72cjogxz 2939 7 had have VBD cord-015369-72cjogxz 2939 8 duodenopancreatectomy duodenopancreatectomy NN cord-015369-72cjogxz 2939 9 almost almost RB cord-015369-72cjogxz 2939 10 equal equal JJ cord-015369-72cjogxz 2939 11 to to IN cord-015369-72cjogxz 2939 12 80 80 CD cord-015369-72cjogxz 2939 13 % % NN cord-015369-72cjogxz 2939 14 of of IN cord-015369-72cjogxz 2939 15 the the DT cord-015369-72cjogxz 2939 16 patients patient NNS cord-015369-72cjogxz 2939 17 younger young JJR cord-015369-72cjogxz 2939 18 than than IN cord-015369-72cjogxz 2939 19 70a 70a NNS cord-015369-72cjogxz 2939 20 . . . cord-015369-72cjogxz 2940 1 There there EX cord-015369-72cjogxz 2940 2 was be VBD cord-015369-72cjogxz 2940 3 no no DT cord-015369-72cjogxz 2940 4 significant significant JJ cord-015369-72cjogxz 2940 5 difference difference NN cord-015369-72cjogxz 2940 6 in in IN cord-015369-72cjogxz 2940 7 perioperative perioperative JJ cord-015369-72cjogxz 2940 8 morbidity morbidity NN cord-015369-72cjogxz 2940 9 ( ( -LRB- cord-015369-72cjogxz 2940 10 29.6 29.6 CD cord-015369-72cjogxz 2940 11 % % NN cord-015369-72cjogxz 2940 12 old old JJ cord-015369-72cjogxz 2940 13 vs. vs. CC cord-015369-72cjogxz 2940 14 34.2 34.2 CD cord-015369-72cjogxz 2940 15 % % NN cord-015369-72cjogxz 2940 16 young young JJ cord-015369-72cjogxz 2940 17 ) ) -RRB- cord-015369-72cjogxz 2940 18 and and CC cord-015369-72cjogxz 2940 19 mortality mortality NN cord-015369-72cjogxz 2940 20 ( ( -LRB- cord-015369-72cjogxz 2940 21 6.2 6.2 CD cord-015369-72cjogxz 2940 22 % % NN cord-015369-72cjogxz 2940 23 old old JJ cord-015369-72cjogxz 2940 24 vs. vs. CC cord-015369-72cjogxz 2940 25 6.9 6.9 CD cord-015369-72cjogxz 2940 26 % % NN cord-015369-72cjogxz 2940 27 young young JJ cord-015369-72cjogxz 2940 28 ) ) -RRB- cord-015369-72cjogxz 2940 29 . . . cord-015369-72cjogxz 2941 1 Mortality mortality NN cord-015369-72cjogxz 2941 2 and and CC cord-015369-72cjogxz 2941 3 morbidity morbidity NN cord-015369-72cjogxz 2941 4 were be VBD cord-015369-72cjogxz 2941 5 0 0 CD cord-015369-72cjogxz 2941 6 % % NN cord-015369-72cjogxz 2941 7 and and CC cord-015369-72cjogxz 2941 8 17.6 17.6 CD cord-015369-72cjogxz 2941 9 % % NN cord-015369-72cjogxz 2941 10 in in IN cord-015369-72cjogxz 2941 11 the the DT cord-015369-72cjogxz 2941 12 group group NN cord-015369-72cjogxz 2941 13 of of IN cord-015369-72cjogxz 2941 14 patients patient NNS cord-015369-72cjogxz 2941 15 80a 80a NNS cord-015369-72cjogxz 2941 16 and and CC cord-015369-72cjogxz 2941 17 older old JJR cord-015369-72cjogxz 2941 18 . . . cord-015369-72cjogxz 2942 1 The the DT cord-015369-72cjogxz 2942 2 median median JJ cord-015369-72cjogxz 2942 3 postoperative postoperative JJ cord-015369-72cjogxz 2942 4 stay stay NN cord-015369-72cjogxz 2942 5 in in IN cord-015369-72cjogxz 2942 6 hospital hospital NN cord-015369-72cjogxz 2942 7 was be VBD cord-015369-72cjogxz 2942 8 13 13 CD cord-015369-72cjogxz 2942 9 days day NNS cord-015369-72cjogxz 2942 10 ( ( -LRB- cord-015369-72cjogxz 2942 11 old old JJ cord-015369-72cjogxz 2942 12 ) ) -RRB- cord-015369-72cjogxz 2942 13 and and CC cord-015369-72cjogxz 2942 14 14 14 CD cord-015369-72cjogxz 2942 15 days day NNS cord-015369-72cjogxz 2942 16 ( ( -LRB- cord-015369-72cjogxz 2942 17 young young JJ cord-015369-72cjogxz 2942 18 ) ) -RRB- cord-015369-72cjogxz 2942 19 respectively respectively RB cord-015369-72cjogxz 2942 20 . . . cord-015369-72cjogxz 2943 1 There there EX cord-015369-72cjogxz 2943 2 was be VBD cord-015369-72cjogxz 2943 3 no no DT cord-015369-72cjogxz 2943 4 observed observed JJ cord-015369-72cjogxz 2943 5 difference difference NN cord-015369-72cjogxz 2943 6 in in IN cord-015369-72cjogxz 2943 7 the the DT cord-015369-72cjogxz 2943 8 mean mean JJ cord-015369-72cjogxz 2943 9 survival survival NN cord-015369-72cjogxz 2943 10 for for IN cord-015369-72cjogxz 2943 11 both both DT cord-015369-72cjogxz 2943 12 groups group NNS cord-015369-72cjogxz 2943 13 ( ( -LRB- cord-015369-72cjogxz 2943 14 20 20 CD cord-015369-72cjogxz 2943 15 months month NNS cord-015369-72cjogxz 2943 16 old old JJ cord-015369-72cjogxz 2943 17 vs. vs. IN cord-015369-72cjogxz 2943 18 22 22 CD cord-015369-72cjogxz 2943 19 months month NNS cord-015369-72cjogxz 2943 20 young young JJ cord-015369-72cjogxz 2943 21 ) ) -RRB- cord-015369-72cjogxz 2943 22 . . . cord-015369-72cjogxz 2944 1 Conclusions conclusion NNS cord-015369-72cjogxz 2944 2 . . . cord-015369-72cjogxz 2945 1 An an DT cord-015369-72cjogxz 2945 2 aggressive aggressive JJ cord-015369-72cjogxz 2945 3 surgical surgical JJ cord-015369-72cjogxz 2945 4 approach approach NN cord-015369-72cjogxz 2945 5 for for IN cord-015369-72cjogxz 2945 6 pancreatic pancreatic JJ cord-015369-72cjogxz 2945 7 cancer cancer NN cord-015369-72cjogxz 2945 8 is be VBZ cord-015369-72cjogxz 2945 9 justified justify VBN cord-015369-72cjogxz 2945 10 in in IN cord-015369-72cjogxz 2945 11 elderly elderly JJ cord-015369-72cjogxz 2945 12 patients patient NNS cord-015369-72cjogxz 2945 13 , , , cord-015369-72cjogxz 2945 14 as as IN cord-015369-72cjogxz 2945 15 they -PRON- PRP cord-015369-72cjogxz 2945 16 can can MD cord-015369-72cjogxz 2945 17 benefit benefit VB cord-015369-72cjogxz 2945 18 from from IN cord-015369-72cjogxz 2945 19 resection resection NN cord-015369-72cjogxz 2945 20 similarly similarly RB cord-015369-72cjogxz 2945 21 to to IN cord-015369-72cjogxz 2945 22 younger young JJR cord-015369-72cjogxz 2945 23 patients patient NNS cord-015369-72cjogxz 2945 24 . . . cord-015369-72cjogxz 2946 1 Is be VBZ cord-015369-72cjogxz 2946 2 preoperative preoperative JJ cord-015369-72cjogxz 2946 3 tissue tissue NN cord-015369-72cjogxz 2946 4 diagnosis diagnosis NN cord-015369-72cjogxz 2946 5 mandatory mandatory JJ cord-015369-72cjogxz 2946 6 for for IN cord-015369-72cjogxz 2946 7 suspect suspect JJ cord-015369-72cjogxz 2946 8 lesions lesion NNS cord-015369-72cjogxz 2946 9 of of IN cord-015369-72cjogxz 2946 10 the the DT cord-015369-72cjogxz 2946 11 pancreas pancrea NNS cord-015369-72cjogxz 2946 12 ? ? . cord-015369-72cjogxz 2947 1 Background background NN cord-015369-72cjogxz 2947 2 . . . cord-015369-72cjogxz 2948 1 It -PRON- PRP cord-015369-72cjogxz 2948 2 is be VBZ cord-015369-72cjogxz 2948 3 still still RB cord-015369-72cjogxz 2948 4 controversial controversial JJ cord-015369-72cjogxz 2948 5 if if IN cord-015369-72cjogxz 2948 6 pretherapeutic pretherapeutic NNP cord-015369-72cjogxz 2948 7 cytohistological cytohistological NNP cord-015369-72cjogxz 2948 8 diagnosis diagnosis NN cord-015369-72cjogxz 2948 9 is be VBZ cord-015369-72cjogxz 2948 10 mandatory mandatory JJ cord-015369-72cjogxz 2948 11 for for IN cord-015369-72cjogxz 2948 12 patients patient NNS cord-015369-72cjogxz 2948 13 with with IN cord-015369-72cjogxz 2948 14 suspect suspect JJ cord-015369-72cjogxz 2948 15 leasions leasion NNS cord-015369-72cjogxz 2948 16 of of IN cord-015369-72cjogxz 2948 17 the the DT cord-015369-72cjogxz 2948 18 pancreas pancrea NNS cord-015369-72cjogxz 2948 19 . . . cord-015369-72cjogxz 2949 1 Even even RB cord-015369-72cjogxz 2949 2 transgastric transgastric JJ cord-015369-72cjogxz 2949 3 endosonographic endosonographic JJ cord-015369-72cjogxz 2949 4 biopsy biopsy NN cord-015369-72cjogxz 2949 5 is be VBZ cord-015369-72cjogxz 2949 6 a a DT cord-015369-72cjogxz 2949 7 save save NN cord-015369-72cjogxz 2949 8 technique technique NN cord-015369-72cjogxz 2949 9 , , , cord-015369-72cjogxz 2949 10 with with IN cord-015369-72cjogxz 2949 11 a a DT cord-015369-72cjogxz 2949 12 sensitivity sensitivity NN cord-015369-72cjogxz 2949 13 of of IN cord-015369-72cjogxz 2949 14 70 70 CD cord-015369-72cjogxz 2949 15 - - SYM cord-015369-72cjogxz 2949 16 80 80 CD cord-015369-72cjogxz 2949 17 % % NN cord-015369-72cjogxz 2949 18 , , , cord-015369-72cjogxz 2949 19 a a DT cord-015369-72cjogxz 2949 20 negative negative JJ cord-015369-72cjogxz 2949 21 result result NN cord-015369-72cjogxz 2949 22 does do VBZ cord-015369-72cjogxz 2949 23 not not RB cord-015369-72cjogxz 2949 24 rule rule VB cord-015369-72cjogxz 2949 25 out out RP cord-015369-72cjogxz 2949 26 malignancy malignancy NN cord-015369-72cjogxz 2949 27 . . . cord-015369-72cjogxz 2950 1 Methods method NNS cord-015369-72cjogxz 2950 2 . . . cord-015369-72cjogxz 2951 1 Medical medical JJ cord-015369-72cjogxz 2951 2 records record NNS cord-015369-72cjogxz 2951 3 of of IN cord-015369-72cjogxz 2951 4 255 255 CD cord-015369-72cjogxz 2951 5 patients patient NNS cord-015369-72cjogxz 2951 6 who who WP cord-015369-72cjogxz 2951 7 underwent undergo VBD cord-015369-72cjogxz 2951 8 surgery surgery NN cord-015369-72cjogxz 2951 9 at at IN cord-015369-72cjogxz 2951 10 our -PRON- PRP$ cord-015369-72cjogxz 2951 11 department department NN cord-015369-72cjogxz 2951 12 , , , cord-015369-72cjogxz 2951 13 between between IN cord-015369-72cjogxz 2951 14 1994 1994 CD cord-015369-72cjogxz 2951 15 and and CC cord-015369-72cjogxz 2951 16 2008 2008 CD cord-015369-72cjogxz 2951 17 , , , cord-015369-72cjogxz 2951 18 for for IN cord-015369-72cjogxz 2951 19 suspected suspect VBN cord-015369-72cjogxz 2951 20 or or CC cord-015369-72cjogxz 2951 21 biopsy biopsy JJ cord-015369-72cjogxz 2951 22 proven prove VBN cord-015369-72cjogxz 2951 23 pancreatic pancreatic JJ cord-015369-72cjogxz 2951 24 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 2951 25 were be VBD cord-015369-72cjogxz 2951 26 analysed analyse VBN cord-015369-72cjogxz 2951 27 and and CC cord-015369-72cjogxz 2951 28 literature literature NN cord-015369-72cjogxz 2951 29 on on IN cord-015369-72cjogxz 2951 30 preoperative preoperative JJ cord-015369-72cjogxz 2951 31 biopsy biopsy NN cord-015369-72cjogxz 2951 32 of of IN cord-015369-72cjogxz 2951 33 suspect suspect JJ cord-015369-72cjogxz 2951 34 pancreatic pancreatic JJ cord-015369-72cjogxz 2951 35 tumors tumor NNS cord-015369-72cjogxz 2951 36 was be VBD cord-015369-72cjogxz 2951 37 reviewed review VBN cord-015369-72cjogxz 2951 38 . . . cord-015369-72cjogxz 2952 1 Results result NNS cord-015369-72cjogxz 2952 2 . . . cord-015369-72cjogxz 2953 1 108 108 CD cord-015369-72cjogxz 2953 2 of of IN cord-015369-72cjogxz 2953 3 186 186 CD cord-015369-72cjogxz 2953 4 patients patient NNS cord-015369-72cjogxz 2953 5 with with IN cord-015369-72cjogxz 2953 6 ductal ductal JJ cord-015369-72cjogxz 2953 7 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 2953 8 had have VBD cord-015369-72cjogxz 2953 9 a a DT cord-015369-72cjogxz 2953 10 biopsy biopsy NN cord-015369-72cjogxz 2953 11 prior prior RB cord-015369-72cjogxz 2953 12 to to IN cord-015369-72cjogxz 2953 13 surgical surgical JJ cord-015369-72cjogxz 2953 14 resection resection NN cord-015369-72cjogxz 2953 15 . . . cord-015369-72cjogxz 2954 1 Of of IN cord-015369-72cjogxz 2954 2 these these DT cord-015369-72cjogxz 2954 3 65 65 CD cord-015369-72cjogxz 2954 4 % % NN cord-015369-72cjogxz 2954 5 ( ( -LRB- cord-015369-72cjogxz 2954 6 n n NN cord-015369-72cjogxz 2954 7 ¼ ¼ NNP cord-015369-72cjogxz 2954 8 70 70 CD cord-015369-72cjogxz 2954 9 ) ) -RRB- cord-015369-72cjogxz 2954 10 were be VBD cord-015369-72cjogxz 2954 11 histological histological JJ cord-015369-72cjogxz 2954 12 diagnosed diagnose VBN cord-015369-72cjogxz 2954 13 as as IN cord-015369-72cjogxz 2954 14 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 2954 15 . . . cord-015369-72cjogxz 2955 1 38 38 CD cord-015369-72cjogxz 2955 2 patients patient NNS cord-015369-72cjogxz 2955 3 underwent undergo VBD cord-015369-72cjogxz 2955 4 surgery surgery NN cord-015369-72cjogxz 2955 5 even even RB cord-015369-72cjogxz 2955 6 after after IN cord-015369-72cjogxz 2955 7 negative negative JJ cord-015369-72cjogxz 2955 8 cyto cyto JJ cord-015369-72cjogxz 2955 9 - - JJ cord-015369-72cjogxz 2955 10 histological histological JJ cord-015369-72cjogxz 2955 11 workup workup NN cord-015369-72cjogxz 2955 12 . . . cord-015369-72cjogxz 2956 1 40 40 CD cord-015369-72cjogxz 2956 2 patients patient NNS cord-015369-72cjogxz 2956 3 had have VBD cord-015369-72cjogxz 2956 4 partitial partitial JJ cord-015369-72cjogxz 2956 5 pancreatic pancreatic JJ cord-015369-72cjogxz 2956 6 resection resection NN cord-015369-72cjogxz 2956 7 without without IN cord-015369-72cjogxz 2956 8 preoperative preoperative JJ cord-015369-72cjogxz 2956 9 biopsy biopsy NN cord-015369-72cjogxz 2956 10 . . . cord-015369-72cjogxz 2957 1 Of of IN cord-015369-72cjogxz 2957 2 29 29 CD cord-015369-72cjogxz 2957 3 patients patient NNS cord-015369-72cjogxz 2957 4 receiving receive VBG cord-015369-72cjogxz 2957 5 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 2957 6 chemotherapy chemotherapy NN cord-015369-72cjogxz 2957 7 90 90 CD cord-015369-72cjogxz 2957 8 % % NN cord-015369-72cjogxz 2957 9 ( ( -LRB- cord-015369-72cjogxz 2957 10 n n NN cord-015369-72cjogxz 2957 11 ¼ ¼ NNP cord-015369-72cjogxz 2957 12 26 26 CD cord-015369-72cjogxz 2957 13 ) ) -RRB- cord-015369-72cjogxz 2957 14 had have VBD cord-015369-72cjogxz 2957 15 histological histological JJ cord-015369-72cjogxz 2957 16 diagnosis diagnosis NN cord-015369-72cjogxz 2957 17 prior prior RB cord-015369-72cjogxz 2957 18 to to IN cord-015369-72cjogxz 2957 19 therapy therapy NN cord-015369-72cjogxz 2957 20 . . . cord-015369-72cjogxz 2958 1 On on IN cord-015369-72cjogxz 2958 2 the the DT cord-015369-72cjogxz 2958 3 other other JJ cord-015369-72cjogxz 2958 4 hand hand NN cord-015369-72cjogxz 2958 5 69 69 CD cord-015369-72cjogxz 2958 6 patients patient NNS cord-015369-72cjogxz 2958 7 with with IN cord-015369-72cjogxz 2958 8 suspect suspect JJ cord-015369-72cjogxz 2958 9 pancreatic pancreatic JJ cord-015369-72cjogxz 2958 10 lesions lesion NNS cord-015369-72cjogxz 2958 11 showed show VBD cord-015369-72cjogxz 2958 12 pancreatitis pancreatitis NN cord-015369-72cjogxz 2958 13 and and CC cord-015369-72cjogxz 2958 14 no no DT cord-015369-72cjogxz 2958 15 malignancy malignancy NN cord-015369-72cjogxz 2958 16 after after IN cord-015369-72cjogxz 2958 17 resection resection NN cord-015369-72cjogxz 2958 18 . . . cord-015369-72cjogxz 2959 1 46 46 CD cord-015369-72cjogxz 2959 2 % % NN cord-015369-72cjogxz 2959 3 of of IN cord-015369-72cjogxz 2959 4 them -PRON- PRP cord-015369-72cjogxz 2959 5 had have VBD cord-015369-72cjogxz 2959 6 biopsy biopsy JJ cord-015369-72cjogxz 2959 7 with with IN cord-015369-72cjogxz 2959 8 negative negative JJ cord-015369-72cjogxz 2959 9 result result NN cord-015369-72cjogxz 2959 10 but but CC cord-015369-72cjogxz 2959 11 underwent undergo VBD cord-015369-72cjogxz 2959 12 operation operation NN cord-015369-72cjogxz 2959 13 due due JJ cord-015369-72cjogxz 2959 14 to to IN cord-015369-72cjogxz 2959 15 preoperative preoperative JJ cord-015369-72cjogxz 2959 16 radiological radiological JJ cord-015369-72cjogxz 2959 17 findings finding NNS cord-015369-72cjogxz 2959 18 and and CC cord-015369-72cjogxz 2959 19 or or CC cord-015369-72cjogxz 2959 20 CA CA NNP cord-015369-72cjogxz 2959 21 19 19 CD cord-015369-72cjogxz 2959 22 - - SYM cord-015369-72cjogxz 2959 23 9 9 CD cord-015369-72cjogxz 2959 24 level level NN cord-015369-72cjogxz 2959 25 . . . cord-015369-72cjogxz 2960 1 Conclusions conclusion NNS cord-015369-72cjogxz 2960 2 . . . cord-015369-72cjogxz 2961 1 Preoperative preoperative JJ cord-015369-72cjogxz 2961 2 biopsy biopsy NN cord-015369-72cjogxz 2961 3 of of IN cord-015369-72cjogxz 2961 4 potentially potentially RB cord-015369-72cjogxz 2961 5 respectable respectable JJ cord-015369-72cjogxz 2961 6 suspect suspect JJ cord-015369-72cjogxz 2961 7 pancreatic pancreatic JJ cord-015369-72cjogxz 2961 8 masses masse NNS cord-015369-72cjogxz 2961 9 is be VBZ cord-015369-72cjogxz 2961 10 not not RB cord-015369-72cjogxz 2961 11 mandatory mandatory JJ cord-015369-72cjogxz 2961 12 as as IN cord-015369-72cjogxz 2961 13 malignancy malignancy NN cord-015369-72cjogxz 2961 14 can can MD cord-015369-72cjogxz 2961 15 not not RB cord-015369-72cjogxz 2961 16 be be VB cord-015369-72cjogxz 2961 17 ruled rule VBN cord-015369-72cjogxz 2961 18 out out RP cord-015369-72cjogxz 2961 19 with with IN cord-015369-72cjogxz 2961 20 adequate adequate JJ cord-015369-72cjogxz 2961 21 reliability reliability NN cord-015369-72cjogxz 2961 22 . . . cord-015369-72cjogxz 2962 1 Only only RB cord-015369-72cjogxz 2962 2 in in IN cord-015369-72cjogxz 2962 3 patients patient NNS cord-015369-72cjogxz 2962 4 undergoing undergo VBG cord-015369-72cjogxz 2962 5 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 2962 6 therapy therapy NN cord-015369-72cjogxz 2962 7 extended extend VBN cord-015369-72cjogxz 2962 8 effort effort NN cord-015369-72cjogxz 2962 9 in in IN cord-015369-72cjogxz 2962 10 receiving receive VBG cord-015369-72cjogxz 2962 11 positive positive JJ cord-015369-72cjogxz 2962 12 biopsy biopsy NN cord-015369-72cjogxz 2962 13 cyto cyto NN cord-015369-72cjogxz 2962 14 - - HYPH cord-015369-72cjogxz 2962 15 histological histological JJ cord-015369-72cjogxz 2962 16 result result NN cord-015369-72cjogxz 2962 17 is be VBZ cord-015369-72cjogxz 2962 18 indicated indicate VBN cord-015369-72cjogxz 2962 19 . . . cord-015369-72cjogxz 2963 1 Wie Wie NNP cord-015369-72cjogxz 2963 2 schlecht schlecht NNP cord-015369-72cjogxz 2963 3 sind sind NN cord-015369-72cjogxz 2963 4 , , , cord-015369-72cjogxz 2963 5 , , , cord-015369-72cjogxz 2963 6 low low JJ cord-015369-72cjogxz 2963 7 volume volume NN cord-015369-72cjogxz 2963 8 hospitals hospital NNS cord-015369-72cjogxz 2963 9 ' ' POS cord-015369-72cjogxz 2963 10 ' ' '' cord-015369-72cjogxz 2963 11 ? ? . cord-015369-72cjogxz 2964 1 Eine Eine NNP cord-015369-72cjogxz 2964 2 kritische kritische NNP cord-015369-72cjogxz 2964 3 Analyse Analyse NNP cord-015369-72cjogxz 2964 4 der der NNP cord-015369-72cjogxz 2964 5 Ergebnisqualität Ergebnisqualität NNP cord-015369-72cjogxz 2964 6 von von NNP cord-015369-72cjogxz 2964 7 Pankreaskopfresektionen Pankreaskopfresektionen NNP cord-015369-72cjogxz 2964 8 an an DT cord-015369-72cjogxz 2964 9 einer einer JJ cord-015369-72cjogxz 2964 10 Peripherieabteilung Peripherieabteilung NNP cord-015369-72cjogxz 2964 11 _SP cord-015369-72cjogxz 2964 12 Dynamic dynamic JJ cord-015369-72cjogxz 2964 13 graciloplasty graciloplasty NN cord-015369-72cjogxz 2964 14 in in IN cord-015369-72cjogxz 2964 15 patients patient NNS cord-015369-72cjogxz 2964 16 with with IN cord-015369-72cjogxz 2964 17 severe severe JJ cord-015369-72cjogxz 2964 18 anal anal JJ cord-015369-72cjogxz 2964 19 sphincter sphincter NN cord-015369-72cjogxz 2964 20 lesiona lesiona NNP cord-015369-72cjogxz 2964 21 method method NN cord-015369-72cjogxz 2964 22 still still RB cord-015369-72cjogxz 2964 23 up up IN cord-015369-72cjogxz 2964 24 - - HYPH cord-015369-72cjogxz 2964 25 to to IN cord-015369-72cjogxz 2964 26 - - HYPH cord-015369-72cjogxz 2964 27 date date NN cord-015369-72cjogxz 2964 28 ? ? . cord-015369-72cjogxz 2965 1 Background background NN cord-015369-72cjogxz 2965 2 . . . cord-015369-72cjogxz 2966 1 Until until IN cord-015369-72cjogxz 2966 2 recently recently RB cord-015369-72cjogxz 2966 3 the the DT cord-015369-72cjogxz 2966 4 dynamic dynamic JJ cord-015369-72cjogxz 2966 5 graciloplasty graciloplasty NN cord-015369-72cjogxz 2966 6 ( ( -LRB- cord-015369-72cjogxz 2966 7 DGP DGP NNP cord-015369-72cjogxz 2966 8 ) ) -RRB- cord-015369-72cjogxz 2966 9 was be VBD cord-015369-72cjogxz 2966 10 one one CD cord-015369-72cjogxz 2966 11 of of IN cord-015369-72cjogxz 2966 12 the the DT cord-015369-72cjogxz 2966 13 most most RBS cord-015369-72cjogxz 2966 14 effective effective JJ cord-015369-72cjogxz 2966 15 techniques technique NNS cord-015369-72cjogxz 2966 16 to to TO cord-015369-72cjogxz 2966 17 create create VB cord-015369-72cjogxz 2966 18 a a DT cord-015369-72cjogxz 2966 19 neo neo JJ cord-015369-72cjogxz 2966 20 - - NN cord-015369-72cjogxz 2966 21 sphincter sphincter NN cord-015369-72cjogxz 2966 22 despite despite IN cord-015369-72cjogxz 2966 23 its -PRON- PRP$ cord-015369-72cjogxz 2966 24 complexity complexity NN cord-015369-72cjogxz 2966 25 . . . cord-015369-72cjogxz 2967 1 Nowadays nowadays RB cord-015369-72cjogxz 2967 2 it -PRON- PRP cord-015369-72cjogxz 2967 3 has have VBZ cord-015369-72cjogxz 2967 4 been be VBN cord-015369-72cjogxz 2967 5 replaced replace VBN cord-015369-72cjogxz 2967 6 by by IN cord-015369-72cjogxz 2967 7 less less JJR cord-015369-72cjogxz 2967 8 invasive invasive JJ cord-015369-72cjogxz 2967 9 methods method NNS cord-015369-72cjogxz 2967 10 in in IN cord-015369-72cjogxz 2967 11 order order NN cord-015369-72cjogxz 2967 12 to to TO cord-015369-72cjogxz 2967 13 treat treat VB cord-015369-72cjogxz 2967 14 the the DT cord-015369-72cjogxz 2967 15 fecal fecal JJ cord-015369-72cjogxz 2967 16 incontinence incontinence NN cord-015369-72cjogxz 2967 17 . . . cord-015369-72cjogxz 2968 1 However however RB cord-015369-72cjogxz 2968 2 DGP DGP NNP cord-015369-72cjogxz 2968 3 still still RB cord-015369-72cjogxz 2968 4 plays play VBZ cord-015369-72cjogxz 2968 5 an an DT cord-015369-72cjogxz 2968 6 important important JJ cord-015369-72cjogxz 2968 7 role role NN cord-015369-72cjogxz 2968 8 and and CC cord-015369-72cjogxz 2968 9 this this DT cord-015369-72cjogxz 2968 10 prospective prospective JJ cord-015369-72cjogxz 2968 11 study study NN cord-015369-72cjogxz 2968 12 shows show VBZ cord-015369-72cjogxz 2968 13 the the DT cord-015369-72cjogxz 2968 14 results result NNS cord-015369-72cjogxz 2968 15 of of IN cord-015369-72cjogxz 2968 16 reconstructive reconstructive JJ cord-015369-72cjogxz 2968 17 surgery surgery NN cord-015369-72cjogxz 2968 18 . . . cord-015369-72cjogxz 2969 1 Methods method NNS cord-015369-72cjogxz 2969 2 . . . cord-015369-72cjogxz 2970 1 From from IN cord-015369-72cjogxz 2970 2 January January NNP cord-015369-72cjogxz 2970 3 until until IN cord-015369-72cjogxz 2970 4 December December NNP cord-015369-72cjogxz 2970 5 2008 2008 CD cord-015369-72cjogxz 2970 6 seven seven CD cord-015369-72cjogxz 2970 7 female female JJ cord-015369-72cjogxz 2970 8 patients patient NNS cord-015369-72cjogxz 2970 9 ( ( -LRB- cord-015369-72cjogxz 2970 10 average average JJ cord-015369-72cjogxz 2970 11 age age NN cord-015369-72cjogxz 2970 12 of of IN cord-015369-72cjogxz 2970 13 43.5 43.5 CD cord-015369-72cjogxz 2970 14 years year NNS cord-015369-72cjogxz 2970 15 , , , cord-015369-72cjogxz 2970 16 range range VBP cord-015369-72cjogxz 2970 17 31 31 CD cord-015369-72cjogxz 2970 18 - - SYM cord-015369-72cjogxz 2970 19 61 61 CD cord-015369-72cjogxz 2970 20 years year NNS cord-015369-72cjogxz 2970 21 ) ) -RRB- cord-015369-72cjogxz 2970 22 were be VBD cord-015369-72cjogxz 2970 23 enrolled enrol VBN cord-015369-72cjogxz 2970 24 in in IN cord-015369-72cjogxz 2970 25 the the DT cord-015369-72cjogxz 2970 26 study study NN cord-015369-72cjogxz 2970 27 . . . cord-015369-72cjogxz 2971 1 Inclusion inclusion NN cord-015369-72cjogxz 2971 2 criteria criterion NNS cord-015369-72cjogxz 2971 3 were be VBD cord-015369-72cjogxz 2971 4 severe severe JJ cord-015369-72cjogxz 2971 5 faecal faecal JJ cord-015369-72cjogxz 2971 6 incontince incontince NN cord-015369-72cjogxz 2971 7 after after IN cord-015369-72cjogxz 2971 8 failed fail VBN cord-015369-72cjogxz 2971 9 conservative conservative JJ cord-015369-72cjogxz 2971 10 treatment treatment NN cord-015369-72cjogxz 2971 11 diagnosis diagnosis NN cord-015369-72cjogxz 2971 12 was be VBD cord-015369-72cjogxz 2971 13 confirmed confirm VBN cord-015369-72cjogxz 2971 14 by by IN cord-015369-72cjogxz 2971 15 rectoscopy rectoscopy NN cord-015369-72cjogxz 2971 16 , , , cord-015369-72cjogxz 2971 17 endo endo NN cord-015369-72cjogxz 2971 18 ultrasonography ultrasonography NN cord-015369-72cjogxz 2971 19 and and CC cord-015369-72cjogxz 2971 20 anal anal JJ cord-015369-72cjogxz 2971 21 manometry manometry NN cord-015369-72cjogxz 2971 22 in in IN cord-015369-72cjogxz 2971 23 preoperative preoperative JJ cord-015369-72cjogxz 2971 24 form form NN cord-015369-72cjogxz 2971 25 according accord VBG cord-015369-72cjogxz 2971 26 to to IN cord-015369-72cjogxz 2971 27 the the DT cord-015369-72cjogxz 2971 28 study study NN cord-015369-72cjogxz 2971 29 protocol protocol NN cord-015369-72cjogxz 2971 30 and and CC cord-015369-72cjogxz 2971 31 the the DT cord-015369-72cjogxz 2971 32 fecal fecal JJ cord-015369-72cjogxz 2971 33 incontinence incontinence NN cord-015369-72cjogxz 2971 34 was be VBD cord-015369-72cjogxz 2971 35 recorded record VBN cord-015369-72cjogxz 2971 36 using use VBG cord-015369-72cjogxz 2971 37 the the DT cord-015369-72cjogxz 2971 38 Wexner Wexner NNP cord-015369-72cjogxz 2971 39 - - HYPH cord-015369-72cjogxz 2971 40 Score Score NNP cord-015369-72cjogxz 2971 41 . . . cord-015369-72cjogxz 2972 1 Postoperative postoperative JJ cord-015369-72cjogxz 2972 2 complications complication NNS cord-015369-72cjogxz 2972 3 were be VBD cord-015369-72cjogxz 2972 4 classified classify VBN cord-015369-72cjogxz 2972 5 in in IN cord-015369-72cjogxz 2972 6 four four CD cord-015369-72cjogxz 2972 7 levels level NNS cord-015369-72cjogxz 2972 8 according accord VBG cord-015369-72cjogxz 2972 9 to to IN cord-015369-72cjogxz 2972 10 Dindo Dindo NNP cord-015369-72cjogxz 2972 11 et et NNP cord-015369-72cjogxz 2972 12 al al NNP cord-015369-72cjogxz 2972 13 . . . cord-015369-72cjogxz 2973 1 Results result NNS cord-015369-72cjogxz 2973 2 . . . cord-015369-72cjogxz 2974 1 Five five CD cord-015369-72cjogxz 2974 2 patients patient NNS cord-015369-72cjogxz 2974 3 suffered suffer VBD cord-015369-72cjogxz 2974 4 a a DT cord-015369-72cjogxz 2974 5 postpartum postpartum NN cord-015369-72cjogxz 2974 6 sphincter sphincter NN cord-015369-72cjogxz 2974 7 lesion lesion NN cord-015369-72cjogxz 2974 8 ( ( -LRB- cord-015369-72cjogxz 2974 9 > > NFP cord-015369-72cjogxz 2974 10 180 180 CD cord-015369-72cjogxz 2974 11 in in IN cord-015369-72cjogxz 2974 12 circumference circumference NN cord-015369-72cjogxz 2974 13 ) ) -RRB- cord-015369-72cjogxz 2974 14 and and CC cord-015369-72cjogxz 2974 15 two two CD cord-015369-72cjogxz 2974 16 a a DT cord-015369-72cjogxz 2974 17 congenital congenital JJ cord-015369-72cjogxz 2974 18 atresia atresia NN cord-015369-72cjogxz 2974 19 of of IN cord-015369-72cjogxz 2974 20 the the DT cord-015369-72cjogxz 2974 21 sphincter sphincter NN cord-015369-72cjogxz 2974 22 muscle muscle NN cord-015369-72cjogxz 2974 23 . . . cord-015369-72cjogxz 2975 1 Postoperatively postoperatively RB cord-015369-72cjogxz 2975 2 , , , cord-015369-72cjogxz 2975 3 one one CD cord-015369-72cjogxz 2975 4 patient patient NN cord-015369-72cjogxz 2975 5 suffered suffer VBD cord-015369-72cjogxz 2975 6 level level NN cord-015369-72cjogxz 2975 7 III III NNP cord-015369-72cjogxz 2975 8 ( ( -LRB- cord-015369-72cjogxz 2975 9 reoperation reoperation NN cord-015369-72cjogxz 2975 10 ) ) -RRB- cord-015369-72cjogxz 2975 11 and and CC cord-015369-72cjogxz 2975 12 three three CD cord-015369-72cjogxz 2975 13 others other NNS cord-015369-72cjogxz 2975 14 level level VBP cord-015369-72cjogxz 2975 15 I -PRON- PRP cord-015369-72cjogxz 2975 16 complications complication NNS cord-015369-72cjogxz 2975 17 ( ( -LRB- cord-015369-72cjogxz 2975 18 hypaesthe- hypaesthe- NNP cord-015369-72cjogxz 2975 19 sia sia NNP cord-015369-72cjogxz 2975 20 distal distal JJ cord-015369-72cjogxz 2975 21 to to IN cord-015369-72cjogxz 2975 22 extraction extraction NN cord-015369-72cjogxz 2975 23 area area NN cord-015369-72cjogxz 2975 24 of of IN cord-015369-72cjogxz 2975 25 the the DT cord-015369-72cjogxz 2975 26 M. M. NNP cord-015369-72cjogxz 2975 27 gracilis gracilis NNP cord-015369-72cjogxz 2975 28 , , , cord-015369-72cjogxz 2975 29 extended extend VBN cord-015369-72cjogxz 2975 30 aches ache NNS cord-015369-72cjogxz 2975 31 due due IN cord-015369-72cjogxz 2975 32 to to IN cord-015369-72cjogxz 2975 33 sores sore NNS cord-015369-72cjogxz 2975 34 in in IN cord-015369-72cjogxz 2975 35 the the DT cord-015369-72cjogxz 2975 36 neurostimulator neurostimulator NN cord-015369-72cjogxz 2975 37 and and CC cord-015369-72cjogxz 2975 38 electrode electrode NNP cord-015369-72cjogxz 2975 39 area area NN cord-015369-72cjogxz 2975 40 ) ) -RRB- cord-015369-72cjogxz 2975 41 . . . cord-015369-72cjogxz 2976 1 After after IN cord-015369-72cjogxz 2976 2 completion completion NN cord-015369-72cjogxz 2976 3 of of IN cord-015369-72cjogxz 2976 4 the the DT cord-015369-72cjogxz 2976 5 muscle muscle NN cord-015369-72cjogxz 2976 6 conditioning conditioning NN cord-015369-72cjogxz 2976 7 ( ( -LRB- cord-015369-72cjogxz 2976 8 eight eight CD cord-015369-72cjogxz 2976 9 weeks week NNS cord-015369-72cjogxz 2976 10 postoperative postoperative JJ cord-015369-72cjogxz 2976 11 ) ) -RRB- cord-015369-72cjogxz 2977 1 the the DT cord-015369-72cjogxz 2977 2 median median JJ cord-015369-72cjogxz 2977 3 Wexner Wexner NNP cord-015369-72cjogxz 2977 4 - - HYPH cord-015369-72cjogxz 2977 5 Score Score NNP cord-015369-72cjogxz 2977 6 was be VBD cord-015369-72cjogxz 2977 7 reduced reduce VBN cord-015369-72cjogxz 2977 8 from from IN cord-015369-72cjogxz 2977 9 preoperatively preoperatively NN cord-015369-72cjogxz 2977 10 18 18 CD cord-015369-72cjogxz 2977 11 ( ( -LRB- cord-015369-72cjogxz 2977 12 range range NNP cord-015369-72cjogxz 2977 13 16 16 CD cord-015369-72cjogxz 2977 14 - - SYM cord-015369-72cjogxz 2977 15 20 20 CD cord-015369-72cjogxz 2977 16 ) ) -RRB- cord-015369-72cjogxz 2977 17 to to IN cord-015369-72cjogxz 2977 18 8 8 CD cord-015369-72cjogxz 2977 19 ( ( -LRB- cord-015369-72cjogxz 2977 20 6 6 CD cord-015369-72cjogxz 2977 21 - - SYM cord-015369-72cjogxz 2977 22 10 10 CD cord-015369-72cjogxz 2977 23 ) ) -RRB- cord-015369-72cjogxz 2977 24 . . . cord-015369-72cjogxz 2978 1 Conclusions conclusion NNS cord-015369-72cjogxz 2978 2 . . . cord-015369-72cjogxz 2979 1 All all DT cord-015369-72cjogxz 2979 2 that that WDT cord-015369-72cjogxz 2979 3 exists exist VBZ cord-015369-72cjogxz 2979 4 today today NN cord-015369-72cjogxz 2979 5 for for IN cord-015369-72cjogxz 2979 6 the the DT cord-015369-72cjogxz 2979 7 DGP DGP NNP cord-015369-72cjogxz 2979 8 is be VBZ cord-015369-72cjogxz 2979 9 a a DT cord-015369-72cjogxz 2979 10 modified modify VBN cord-015369-72cjogxz 2979 11 indication indication NN cord-015369-72cjogxz 2979 12 list list NN cord-015369-72cjogxz 2979 13 . . . cord-015369-72cjogxz 2980 1 In in IN cord-015369-72cjogxz 2980 2 young young JJ cord-015369-72cjogxz 2980 3 patients patient NNS cord-015369-72cjogxz 2980 4 with with IN cord-015369-72cjogxz 2980 5 irreparable irreparable JJ cord-015369-72cjogxz 2980 6 sphincter sphincter NN cord-015369-72cjogxz 2980 7 lesion lesion NN cord-015369-72cjogxz 2980 8 or or CC cord-015369-72cjogxz 2980 9 congenital congenital JJ cord-015369-72cjogxz 2980 10 atresia atresia NN cord-015369-72cjogxz 2980 11 of of IN cord-015369-72cjogxz 2980 12 the the DT cord-015369-72cjogxz 2980 13 sphincter sphincter NN cord-015369-72cjogxz 2980 14 muscle muscle NN cord-015369-72cjogxz 2981 1 the the DT cord-015369-72cjogxz 2981 2 DGP DGP NNP cord-015369-72cjogxz 2981 3 remains remain VBZ cord-015369-72cjogxz 2981 4 an an DT cord-015369-72cjogxz 2981 5 effective effective JJ cord-015369-72cjogxz 2981 6 method method NN cord-015369-72cjogxz 2981 7 in in IN cord-015369-72cjogxz 2981 8 therapy therapy NN cord-015369-72cjogxz 2981 9 with with IN cord-015369-72cjogxz 2981 10 moderate moderate JJ cord-015369-72cjogxz 2981 11 morbidity morbidity NN cord-015369-72cjogxz 2981 12 . . . cord-015369-72cjogxz 2982 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 2982 2 . . . cord-015369-72cjogxz 2983 1 Die die VB cord-015369-72cjogxz 2983 2 Versorgung Versorgung NNP cord-015369-72cjogxz 2983 3 von von NNP cord-015369-72cjogxz 2983 4 Narbenhernien Narbenhernien NNP cord-015369-72cjogxz 2983 5 mittels mittels NNPS cord-015369-72cjogxz 2983 6 offener offener NNP cord-015369-72cjogxz 2984 1 oder oder NNP cord-015369-72cjogxz 2984 2 laparoskopischer laparoskopischer NNP cord-015369-72cjogxz 2984 3 Technik Technik NNP cord-015369-72cjogxz 2984 4 kann kann NNP cord-015369-72cjogxz 2984 5 in in IN cord-015369-72cjogxz 2984 6 Wundkomplikationen Wundkomplikationen NNP cord-015369-72cjogxz 2984 7 und und NNP cord-015369-72cjogxz 2984 8 Hernienrezidiven Hernienrezidiven NNP cord-015369-72cjogxz 2984 9 resultieren resultieren NNP cord-015369-72cjogxz 2984 10 . . . cord-015369-72cjogxz 2985 1 Mittels Mittels NNP cord-015369-72cjogxz 2985 2 NOTES note NNS cord-015369-72cjogxz 2985 3 Techniken Techniken NNP cord-015369-72cjogxz 2985 4 könnten könnten RB cord-015369-72cjogxz 2986 1 diese diese NNP cord-015369-72cjogxz 2986 2 Komplikationen Komplikationen NNP cord-015369-72cjogxz 2986 3 verhindert verhindert NNP cord-015369-72cjogxz 2986 4 werden werden NNP cord-015369-72cjogxz 2986 5 . . . cord-015369-72cjogxz 2987 1 Methodik Methodik NNP cord-015369-72cjogxz 2987 2 . . . cord-015369-72cjogxz 2988 1 In in IN cord-015369-72cjogxz 2988 2 6 6 CD cord-015369-72cjogxz 2988 3 Hausschweinen Hausschweinen NNP cord-015369-72cjogxz 2988 4 erfolgte erfolgte NN cord-015369-72cjogxz 2988 5 die die VB cord-015369-72cjogxz 2989 1 Herstellung Herstellung NNP cord-015369-72cjogxz 2989 2 einer einer NN cord-015369-72cjogxz 2989 3 ventralen ventralen NNP cord-015369-72cjogxz 2990 1 Bauchhernie Bauchhernie NNP cord-015369-72cjogxz 2990 2 durch durch NNP cord-015369-72cjogxz 2990 3 Resektion Resektion NNP cord-015369-72cjogxz 2990 4 eines eine NNS cord-015369-72cjogxz 2991 1 runden runden NNP cord-015369-72cjogxz 2991 2 5 5 CD cord-015369-72cjogxz 2991 3 cm cm NNP cord-015369-72cjogxz 2992 1 i -PRON- PRP cord-015369-72cjogxz 2992 2 m be VBP cord-015369-72cjogxz 2992 3 DM DM NNP cord-015369-72cjogxz 2992 4 haltenden haltenden NNP cord-015369-72cjogxz 2992 5 muskulären muskulären NNP cord-015369-72cjogxz 2992 6 Defektes Defektes NNP cord-015369-72cjogxz 2992 7 . . . cord-015369-72cjogxz 2993 1 Nach Nach NNP cord-015369-72cjogxz 2993 2 4 4 CD cord-015369-72cjogxz 2993 3 Wochen Wochen NNP cord-015369-72cjogxz 2993 4 erfolgte erfolgte NN cord-015369-72cjogxz 2994 1 der der NNP cord-015369-72cjogxz 2994 2 transgastrische transgastrische NNP cord-015369-72cjogxz 2995 1 Verschluß Verschluß NNP cord-015369-72cjogxz 2995 2 der der NNP cord-015369-72cjogxz 2995 3 resultierenden resultierenden JJ cord-015369-72cjogxz 2995 4 Hernie Hernie NNP cord-015369-72cjogxz 2995 5 mittels mittel NNS cord-015369-72cjogxz 2995 6 eines eines NNP cord-015369-72cjogxz 2996 1 über über NNP cord-015369-72cjogxz 2996 2 einen einen NNP cord-015369-72cjogxz 2996 3 Overtube Overtube NNP cord-015369-72cjogxz 2996 4 eingebrachtem eingebrachtem NN cord-015369-72cjogxz 2996 5 biologischen biologischen NNP cord-015369-72cjogxz 2996 6 Netzes Netzes NNP cord-015369-72cjogxz 2996 7 mit mit NNP cord-015369-72cjogxz 2997 1 5 5 CD cord-015369-72cjogxz 2997 2 cm cm NNS cord-015369-72cjogxz 2997 3 allseitiger allseitiger NNP cord-015369-72cjogxz 2997 4 Ü Ü NNP cord-015369-72cjogxz 2997 5 berlappung berlappung NNP cord-015369-72cjogxz 2997 6 und und IN cord-015369-72cjogxz 2997 7 Fixation Fixation NNP cord-015369-72cjogxz 2997 8 mit mit NNP cord-015369-72cjogxz 2997 9 transfascialen transfascialen NNP cord-015369-72cjogxz 2997 10 Nähten Nähten NNP cord-015369-72cjogxz 2997 11 . . . cord-015369-72cjogxz 2998 1 Nach Nach NNP cord-015369-72cjogxz 2998 2 zwei zwei CD cord-015369-72cjogxz 2998 3 Wochen Wochen NNP cord-015369-72cjogxz 2998 4 erfolgte erfolgte NN cord-015369-72cjogxz 2999 1 eine eine NNP cord-015369-72cjogxz 2999 2 explorative explorative NNP cord-015369-72cjogxz 2999 3 Laparoskopie Laparoskopie NNP cord-015369-72cjogxz 2999 4 und und IN cord-015369-72cjogxz 2999 5 nach nach NNP cord-015369-72cjogxz 2999 6 weiteren weiteren NNP cord-015369-72cjogxz 2999 7 2 2 CD cord-015369-72cjogxz 2999 8 Wochen Wochen NNP cord-015369-72cjogxz 2999 9 wurden wurden NNS cord-015369-72cjogxz 2999 10 die die VBP cord-015369-72cjogxz 3000 1 Tiere Tiere NNP cord-015369-72cjogxz 3000 2 euthanasiert euthanasiert NN cord-015369-72cjogxz 3000 3 und und NNP cord-015369-72cjogxz 3000 4 obduziert obduziert NNP cord-015369-72cjogxz 3000 5 . . . cord-015369-72cjogxz 3001 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 3001 2 . . . cord-015369-72cjogxz 3002 1 Die die VB cord-015369-72cjogxz 3002 2 Größe Größe NNP cord-015369-72cjogxz 3002 3 der der NNP cord-015369-72cjogxz 3002 4 Hernien Hernien NNP cord-015369-72cjogxz 3002 5 lag lag VBP cord-015369-72cjogxz 3002 6 zwischen zwischen NNP cord-015369-72cjogxz 3002 7 36 36 CD cord-015369-72cjogxz 3002 8 und und NN cord-015369-72cjogxz 3002 9 90 90 CD cord-015369-72cjogxz 3002 10 cm cm NNS cord-015369-72cjogxz 3002 11 2 2 CD cord-015369-72cjogxz 3002 12 . . . cord-015369-72cjogxz 3003 1 In in IN cord-015369-72cjogxz 3003 2 allen allen NNP cord-015369-72cjogxz 3003 3 6 6 CD cord-015369-72cjogxz 3003 4 Tieren Tieren NNP cord-015369-72cjogxz 3003 5 konnte konnte NNP cord-015369-72cjogxz 3003 6 ein ein NNP cord-015369-72cjogxz 3003 7 Hernienverschluss Hernienverschluss NNP cord-015369-72cjogxz 3003 8 mit mit NNP cord-015369-72cjogxz 3003 9 einer einer NNP cord-015369-72cjogxz 3003 10 mittleren mittleren NNP cord-015369-72cjogxz 3003 11 Operationszeit Operationszeit NNP cord-015369-72cjogxz 3003 12 von von NNP cord-015369-72cjogxz 3003 13 204 204 CD cord-015369-72cjogxz 3003 14 AE AE NNP cord-015369-72cjogxz 3003 15 123 123 CD cord-015369-72cjogxz 3003 16 Minuten Minuten NNP cord-015369-72cjogxz 3003 17 durchgefü durchgefü NN cord-015369-72cjogxz 3003 18 hrt hrt NNP cord-015369-72cjogxz 3003 19 werden werden NNP cord-015369-72cjogxz 3003 20 . . . cord-015369-72cjogxz 3004 1 Die die VB cord-015369-72cjogxz 3005 1 Größe Größe NNP cord-015369-72cjogxz 3005 2 der der XX cord-015369-72cjogxz 3005 3 implantierten implantierten NNP cord-015369-72cjogxz 3005 4 Netze Netze NNP cord-015369-72cjogxz 3005 5 lag lag VBP cord-015369-72cjogxz 3005 6 zwischen zwischen NNP cord-015369-72cjogxz 3005 7 16 16 CD cord-015369-72cjogxz 3005 8 Â â CD cord-015369-72cjogxz 3005 9 16 16 CD cord-015369-72cjogxz 3005 10 und und CD cord-015369-72cjogxz 3005 11 20 20 CD cord-015369-72cjogxz 3005 12 Â â CD cord-015369-72cjogxz 3005 13 19 19 CD cord-015369-72cjogxz 3005 14 cm cm NNS cord-015369-72cjogxz 3005 15 . . . cord-015369-72cjogxz 3006 1 Ein Ein NNP cord-015369-72cjogxz 3006 2 Tier Tier NNP cord-015369-72cjogxz 3006 3 verstarb verstarb NN cord-015369-72cjogxz 3006 4 unmittelbar unmittelbar NN cord-015369-72cjogxz 3006 5 postoperativ postoperativ NNP cord-015369-72cjogxz 3006 6 an an DT cord-015369-72cjogxz 3006 7 Hypoxie Hypoxie NNP cord-015369-72cjogxz 3006 8 . . . cord-015369-72cjogxz 3007 1 Bei Bei NNP cord-015369-72cjogxz 3007 2 der der NNP cord-015369-72cjogxz 3008 1 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 3008 2 Exploration Exploration NNP cord-015369-72cjogxz 3008 3 nach nach NNP cord-015369-72cjogxz 3008 4 2 2 CD cord-015369-72cjogxz 3009 1 Wochen Wochen NNP cord-015369-72cjogxz 3009 2 fanden fanden NNP cord-015369-72cjogxz 3009 3 sich sich NNP cord-015369-72cjogxz 3009 4 in in IN cord-015369-72cjogxz 3009 5 allen allen NNP cord-015369-72cjogxz 3009 6 Tiere Tiere NNP cord-015369-72cjogxz 3009 7 massive massive JJ cord-015369-72cjogxz 3009 8 Adhäsionen Adhäsionen NNP cord-015369-72cjogxz 3009 9 , , , cord-015369-72cjogxz 3009 10 ein ein NNP cord-015369-72cjogxz 3009 11 Tier Tier NNP cord-015369-72cjogxz 3009 12 wurde wurde NN cord-015369-72cjogxz 3009 13 aufgrund aufgrund NNP cord-015369-72cjogxz 3009 14 einer einer NNP cord-015369-72cjogxz 3009 15 Netzinfektion Netzinfektion NNP cord-015369-72cjogxz 3009 16 euthanasiert euthanasiert NNP cord-015369-72cjogxz 3009 17 . . . cord-015369-72cjogxz 3010 1 Die die VB cord-015369-72cjogxz 3010 2 ü ü . cord-015369-72cjogxz 3011 1 brigen brigen NNP cord-015369-72cjogxz 3011 2 Tieren Tieren NNP cord-015369-72cjogxz 3011 3 ü ü NN cord-015369-72cjogxz 3011 4 berlebten berlebten NNP cord-015369-72cjogxz 3011 5 die die VBP cord-015369-72cjogxz 3011 6 vierwöchige vierwöchige NNP cord-015369-72cjogxz 3011 7 Beobachtungszeit Beobachtungszeit NNP cord-015369-72cjogxz 3011 8 . . . cord-015369-72cjogxz 3012 1 In in IN cord-015369-72cjogxz 3012 2 allen allen NNP cord-015369-72cjogxz 3012 3 Tieren Tieren NNP cord-015369-72cjogxz 3012 4 fand fand NN cord-015369-72cjogxz 3012 5 sich sich NNP cord-015369-72cjogxz 3012 6 bei bei XX cord-015369-72cjogxz 3012 7 der der NNP cord-015369-72cjogxz 3012 8 Obduktion Obduktion NNP cord-015369-72cjogxz 3012 9 ein ein NN cord-015369-72cjogxz 3012 10 erfolgreicher erfolgreicher NN cord-015369-72cjogxz 3012 11 Hernienverschluss Hernienverschluss NNP cord-015369-72cjogxz 3012 12 . . . cord-015369-72cjogxz 3013 1 Alle Alle NNP cord-015369-72cjogxz 3013 2 Tiere Tiere NNP cord-015369-72cjogxz 3014 1 hatten hatten NNP cord-015369-72cjogxz 3014 2 Netzinfektionen Netzinfektionen NNP cord-015369-72cjogxz 3014 3 . . . cord-015369-72cjogxz 3015 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 3015 2 . . . cord-015369-72cjogxz 3016 1 Der Der NNP cord-015369-72cjogxz 3016 2 transgastrische transgastrische NNP cord-015369-72cjogxz 3017 1 Verschluss Verschluss NNP cord-015369-72cjogxz 3018 1 von von NNP cord-015369-72cjogxz 3018 2 großen großen NNP cord-015369-72cjogxz 3019 1 ventralen ventralen NNP cord-015369-72cjogxz 3020 1 Bauchwandhernien Bauchwandhernien NNP cord-015369-72cjogxz 3020 2 ist ist FW cord-015369-72cjogxz 3020 3 technisch technisch NNP cord-015369-72cjogxz 3020 4 machbar machbar NN cord-015369-72cjogxz 3020 5 . . . cord-015369-72cjogxz 3021 1 Das Das NNP cord-015369-72cjogxz 3021 2 sterile sterile JJ cord-015369-72cjogxz 3021 3 transgastrische transgastrische NN cord-015369-72cjogxz 3022 1 Einbringen Einbringen NNP cord-015369-72cjogxz 3022 2 des des FW cord-015369-72cjogxz 3022 3 Netzes Netzes NNP cord-015369-72cjogxz 3023 1 und und NNP cord-015369-72cjogxz 3023 2 die die VB cord-015369-72cjogxz 3024 1 Verhinderung Verhinderung NNP cord-015369-72cjogxz 3024 2 von von NNP cord-015369-72cjogxz 3024 3 Netzinfektionen Netzinfektionen NNP cord-015369-72cjogxz 3024 4 stellen stellen NNP cord-015369-72cjogxz 3024 5 derzeit derzeit NNP cord-015369-72cjogxz 3024 6 die die VBP cord-015369-72cjogxz 3024 7 größten größten NNP cord-015369-72cjogxz 3025 1 Hürden Hürden NNP cord-015369-72cjogxz 3025 2 dar dar NNP cord-015369-72cjogxz 3025 3 die die VB cord-015369-72cjogxz 3025 4 überwunden überwunden NNP cord-015369-72cjogxz 3025 5 werden werden NNP cord-015369-72cjogxz 3025 6 müssen müssen NNP cord-015369-72cjogxz 3025 7 , , , cord-015369-72cjogxz 3025 8 bevor bevor NNP cord-015369-72cjogxz 3025 9 dieser dieser NNP cord-015369-72cjogxz 3025 10 Eingriff Eingriff NNP cord-015369-72cjogxz 3025 11 bei bei NNP cord-015369-72cjogxz 3025 12 Menschen Menschen NNP cord-015369-72cjogxz 3025 13 in in IN cord-015369-72cjogxz 3025 14 Erwägung Erwägung NNP cord-015369-72cjogxz 3025 15 gezogen gezogen NNP cord-015369-72cjogxz 3025 16 werden werden NNP cord-015369-72cjogxz 3025 17 kann kann NNP cord-015369-72cjogxz 3025 18 . . . cord-015369-72cjogxz 3026 1 Background background NN cord-015369-72cjogxz 3026 2 . . . cord-015369-72cjogxz 3027 1 Transgastric Transgastric NNP cord-015369-72cjogxz 3027 2 NOTES note NNS cord-015369-72cjogxz 3027 3 procedures procedure NNS cord-015369-72cjogxz 3027 4 remain remain VBP cord-015369-72cjogxz 3027 5 difficult difficult JJ cord-015369-72cjogxz 3027 6 due due IN cord-015369-72cjogxz 3027 7 to to IN cord-015369-72cjogxz 3027 8 the the DT cord-015369-72cjogxz 3027 9 lake lake NN cord-015369-72cjogxz 3027 10 of of IN cord-015369-72cjogxz 3027 11 innovative innovative JJ cord-015369-72cjogxz 3027 12 flexible flexible JJ cord-015369-72cjogxz 3027 13 endoscopic endoscopic NNS cord-015369-72cjogxz 3027 14 technology technology NN cord-015369-72cjogxz 3027 15 . . . cord-015369-72cjogxz 3028 1 In in IN cord-015369-72cjogxz 3028 2 particular particular JJ cord-015369-72cjogxz 3028 3 , , , cord-015369-72cjogxz 3028 4 independent independent JJ cord-015369-72cjogxz 3028 5 movement movement NN cord-015369-72cjogxz 3028 6 of of IN cord-015369-72cjogxz 3028 7 the the DT cord-015369-72cjogxz 3028 8 instruments instrument NNS cord-015369-72cjogxz 3028 9 from from IN cord-015369-72cjogxz 3028 10 the the DT cord-015369-72cjogxz 3028 11 visual visual JJ cord-015369-72cjogxz 3028 12 axis axis NN cord-015369-72cjogxz 3028 13 has have VBZ cord-015369-72cjogxz 3028 14 been be VBN cord-015369-72cjogxz 3028 15 described describe VBN cord-015369-72cjogxz 3028 16 as as IN cord-015369-72cjogxz 3028 17 an an DT cord-015369-72cjogxz 3028 18 essential essential JJ cord-015369-72cjogxz 3028 19 part part NN cord-015369-72cjogxz 3028 20 of of IN cord-015369-72cjogxz 3028 21 complex complex JJ cord-015369-72cjogxz 3028 22 NOTES note NNS cord-015369-72cjogxz 3028 23 procedures procedure NNS cord-015369-72cjogxz 3028 24 . . . cord-015369-72cjogxz 3029 1 Methods method NNS cord-015369-72cjogxz 3029 2 . . . cord-015369-72cjogxz 3030 1 We -PRON- PRP cord-015369-72cjogxz 3030 2 present present VBP cord-015369-72cjogxz 3030 3 our -PRON- PRP$ cord-015369-72cjogxz 3030 4 experience experience NN cord-015369-72cjogxz 3030 5 using use VBG cord-015369-72cjogxz 3030 6 the the DT cord-015369-72cjogxz 3030 7 Endo Endo NNP cord-015369-72cjogxz 3030 8 - - HYPH cord-015369-72cjogxz 3030 9 SAMURAI SAMURAI NNP cord-015369-72cjogxz 3030 10 TM TM NNP cord-015369-72cjogxz 3030 11 ( ( -LRB- cord-015369-72cjogxz 3030 12 Olympus Olympus NNP cord-015369-72cjogxz 3030 13 ) ) -RRB- cord-015369-72cjogxz 3030 14 newly newly RB cord-015369-72cjogxz 3030 15 designed design VBN cord-015369-72cjogxz 3030 16 prototype prototype NN cord-015369-72cjogxz 3030 17 platform platform NN cord-015369-72cjogxz 3030 18 for for IN cord-015369-72cjogxz 3030 19 advanced advanced JJ cord-015369-72cjogxz 3030 20 endoscopic endoscopic JJ cord-015369-72cjogxz 3030 21 surgery surgery NN cord-015369-72cjogxz 3030 22 , , , cord-015369-72cjogxz 3030 23 which which WDT cord-015369-72cjogxz 3030 24 is be VBZ cord-015369-72cjogxz 3030 25 15 15 CD cord-015369-72cjogxz 3030 26 mm mm NNS cord-015369-72cjogxz 3030 27 in in IN cord-015369-72cjogxz 3030 28 OD OD NNP cord-015369-72cjogxz 3030 29 and and CC cord-015369-72cjogxz 3030 30 which which WDT cord-015369-72cjogxz 3030 31 allows allow VBZ cord-015369-72cjogxz 3030 32 5 5 CD cord-015369-72cjogxz 3030 33 of of IN cord-015369-72cjogxz 3030 34 freedom freedom NN cord-015369-72cjogxz 3030 35 at at IN cord-015369-72cjogxz 3030 36 the the DT cord-015369-72cjogxz 3030 37 instrument instrument NN cord-015369-72cjogxz 3030 38 tips tip NNS cord-015369-72cjogxz 3030 39 with with IN cord-015369-72cjogxz 3030 40 a a DT cord-015369-72cjogxz 3030 41 variety variety NN cord-015369-72cjogxz 3030 42 of of IN cord-015369-72cjogxz 3030 43 instrument instrument NN cord-015369-72cjogxz 3030 44 configurations configuration NNS cord-015369-72cjogxz 3030 45 , , , cord-015369-72cjogxz 3030 46 in in IN cord-015369-72cjogxz 3030 47 an an DT cord-015369-72cjogxz 3030 48 animal animal NN cord-015369-72cjogxz 3030 49 model model NN cord-015369-72cjogxz 3030 50 to to TO cord-015369-72cjogxz 3030 51 perform perform VB cord-015369-72cjogxz 3030 52 transgastric transgastric JJ cord-015369-72cjogxz 3030 53 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 3030 54 . . . cord-015369-72cjogxz 3031 1 Results result NNS cord-015369-72cjogxz 3031 2 . . . cord-015369-72cjogxz 3032 1 A a DT cord-015369-72cjogxz 3032 2 porcine porcine JJ cord-015369-72cjogxz 3032 3 model model NN cord-015369-72cjogxz 3032 4 was be VBD cord-015369-72cjogxz 3032 5 used use VBN cord-015369-72cjogxz 3032 6 to to TO cord-015369-72cjogxz 3032 7 perform perform VB cord-015369-72cjogxz 3032 8 transgastric transgastric JJ cord-015369-72cjogxz 3032 9 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 3032 10 with with IN cord-015369-72cjogxz 3032 11 the the DT cord-015369-72cjogxz 3032 12 new new JJ cord-015369-72cjogxz 3032 13 device device NN cord-015369-72cjogxz 3032 14 . . . cord-015369-72cjogxz 3033 1 Gastric gastric JJ cord-015369-72cjogxz 3033 2 exit exit NN cord-015369-72cjogxz 3033 3 was be VBD cord-015369-72cjogxz 3033 4 easily easily RB cord-015369-72cjogxz 3033 5 performed perform VBN cord-015369-72cjogxz 3033 6 using use VBG cord-015369-72cjogxz 3033 7 an an DT cord-015369-72cjogxz 3033 8 overtube overtube NN cord-015369-72cjogxz 3033 9 and and CC cord-015369-72cjogxz 3033 10 needle needle NN cord-015369-72cjogxz 3033 11 knife knife NN cord-015369-72cjogxz 3033 12 in in IN cord-015369-72cjogxz 3033 13 22 22 CD cord-015369-72cjogxz 3033 14 min min NN cord-015369-72cjogxz 3033 15 . . . cord-015369-72cjogxz 3034 1 The the DT cord-015369-72cjogxz 3034 2 gallbladder gallbladder NN cord-015369-72cjogxz 3034 3 was be VBD cord-015369-72cjogxz 3034 4 easily easily RB cord-015369-72cjogxz 3034 5 identified identify VBN cord-015369-72cjogxz 3034 6 and and CC cord-015369-72cjogxz 3034 7 dissected dissect VBN cord-015369-72cjogxz 3034 8 in in IN cord-015369-72cjogxz 3034 9 a a DT cord-015369-72cjogxz 3034 10 manner manner NN cord-015369-72cjogxz 3034 11 similar similar JJ cord-015369-72cjogxz 3034 12 to to IN cord-015369-72cjogxz 3034 13 laparoscopic laparoscopic JJ cord-015369-72cjogxz 3034 14 procedures procedure NNS cord-015369-72cjogxz 3034 15 using use VBG cord-015369-72cjogxz 3034 16 graspers grasper NNS cord-015369-72cjogxz 3034 17 and and CC cord-015369-72cjogxz 3034 18 hook hook VB cord-015369-72cjogxz 3034 19 cautery cautery NN cord-015369-72cjogxz 3034 20 instruments instrument NNS cord-015369-72cjogxz 3034 21 with with IN cord-015369-72cjogxz 3034 22 5 5 CD cord-015369-72cjogxz 3034 23 of of IN cord-015369-72cjogxz 3034 24 freedom freedom NN cord-015369-72cjogxz 3034 25 . . . cord-015369-72cjogxz 3035 1 Good good JJ cord-015369-72cjogxz 3035 2 user user NN cord-015369-72cjogxz 3035 3 ergonomics ergonomic NNS cord-015369-72cjogxz 3035 4 were be VBD cord-015369-72cjogxz 3035 5 recorded record VBN cord-015369-72cjogxz 3035 6 and and CC cord-015369-72cjogxz 3035 7 the the DT cord-015369-72cjogxz 3035 8 GB GB NNP cord-015369-72cjogxz 3035 9 was be VBD cord-015369-72cjogxz 3035 10 removed remove VBN cord-015369-72cjogxz 3035 11 without without IN cord-015369-72cjogxz 3035 12 spillage spillage NN cord-015369-72cjogxz 3035 13 in in IN cord-015369-72cjogxz 3035 14 55 55 CD cord-015369-72cjogxz 3035 15 min min NN cord-015369-72cjogxz 3035 16 . . . cord-015369-72cjogxz 3036 1 Gastric gastric JJ cord-015369-72cjogxz 3036 2 closure closure NN cord-015369-72cjogxz 3036 3 was be VBD cord-015369-72cjogxz 3036 4 attempted attempt VBN cord-015369-72cjogxz 3036 5 with with IN cord-015369-72cjogxz 3036 6 intracorporeal intracorporeal NN cord-015369-72cjogxz 3036 7 suturing suturing NN cord-015369-72cjogxz 3036 8 but but CC cord-015369-72cjogxz 3036 9 was be VBD cord-015369-72cjogxz 3036 10 still still RB cord-015369-72cjogxz 3036 11 difficult difficult JJ cord-015369-72cjogxz 3036 12 due due IN cord-015369-72cjogxz 3036 13 to to IN cord-015369-72cjogxz 3036 14 grasping grasp VBG cord-015369-72cjogxz 3036 15 strength strength NN cord-015369-72cjogxz 3036 16 of of IN cord-015369-72cjogxz 3036 17 the the DT cord-015369-72cjogxz 3036 18 needle needle NN cord-015369-72cjogxz 3036 19 holders holder NNS cord-015369-72cjogxz 3036 20 and and CC cord-015369-72cjogxz 3036 21 visualization visualization NN cord-015369-72cjogxz 3036 22 due due IN cord-015369-72cjogxz 3036 23 to to IN cord-015369-72cjogxz 3036 24 loss loss NN cord-015369-72cjogxz 3036 25 of of IN cord-015369-72cjogxz 3036 26 pneumo pneumo NN cord-015369-72cjogxz 3036 27 - - HYPH cord-015369-72cjogxz 3036 28 gastrium gastrium JJ cord-015369-72cjogxz 3036 29 . . . cord-015369-72cjogxz 3037 1 Conclusions conclusion NNS cord-015369-72cjogxz 3037 2 . . . cord-015369-72cjogxz 3038 1 The the DT cord-015369-72cjogxz 3038 2 new new JJ cord-015369-72cjogxz 3038 3 EndoSAMURAI EndoSAMURAI NNP cord-015369-72cjogxz 3038 4 TM TM NNP cord-015369-72cjogxz 3038 5 device device NN cord-015369-72cjogxz 3038 6 offers offer VBZ cord-015369-72cjogxz 3038 7 substantial substantial JJ cord-015369-72cjogxz 3038 8 advantage advantage NN cord-015369-72cjogxz 3038 9 to to IN cord-015369-72cjogxz 3038 10 the the DT cord-015369-72cjogxz 3038 11 performance performance NN cord-015369-72cjogxz 3038 12 of of IN cord-015369-72cjogxz 3038 13 transgastric transgastric NNP cord-015369-72cjogxz 3038 14 NOTES NOTES NNPS cord-015369-72cjogxz 3038 15 procedures procedure NNS cord-015369-72cjogxz 3038 16 and and CC cord-015369-72cjogxz 3038 17 may may MD cord-015369-72cjogxz 3038 18 represent represent VB cord-015369-72cjogxz 3038 19 the the DT cord-015369-72cjogxz 3038 20 configuration configuration NN cord-015369-72cjogxz 3038 21 of of IN cord-015369-72cjogxz 3038 22 operating operate VBG cord-015369-72cjogxz 3038 23 flexible flexible JJ cord-015369-72cjogxz 3038 24 endoscopes endoscope NNS cord-015369-72cjogxz 3038 25 of of IN cord-015369-72cjogxz 3038 26 the the DT cord-015369-72cjogxz 3038 27 future future NN cord-015369-72cjogxz 3038 28 . . . cord-015369-72cjogxz 3039 1 Background background NN cord-015369-72cjogxz 3039 2 . . . cord-015369-72cjogxz 3040 1 Laparoscopic laparoscopic JJ cord-015369-72cjogxz 3040 2 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 3040 3 has have VBZ cord-015369-72cjogxz 3040 4 become become VBN cord-015369-72cjogxz 3040 5 standard standard JJ cord-015369-72cjogxz 3040 6 procedure procedure NN cord-015369-72cjogxz 3040 7 . . . cord-015369-72cjogxz 3041 1 Natural natural JJ cord-015369-72cjogxz 3041 2 orifice orifice NN cord-015369-72cjogxz 3041 3 transluminal transluminal JJ cord-015369-72cjogxz 3041 4 endoscopic endoscopic NNS cord-015369-72cjogxz 3041 5 surgery surgery NN cord-015369-72cjogxz 3042 1 ( ( -LRB- cord-015369-72cjogxz 3042 2 NOTES note NNS cord-015369-72cjogxz 3042 3 ) ) -RRB- cord-015369-72cjogxz 3042 4 will will MD cord-015369-72cjogxz 3042 5 further further RB cord-015369-72cjogxz 3042 6 decrease decrease VB cord-015369-72cjogxz 3042 7 the the DT cord-015369-72cjogxz 3042 8 operative operative JJ cord-015369-72cjogxz 3042 9 trauma trauma NN cord-015369-72cjogxz 3042 10 to to IN cord-015369-72cjogxz 3042 11 the the DT cord-015369-72cjogxz 3042 12 abdominal abdominal JJ cord-015369-72cjogxz 3042 13 wall wall NN cord-015369-72cjogxz 3042 14 and and CC cord-015369-72cjogxz 3042 15 reduce reduce VB cord-015369-72cjogxz 3042 16 postoperative postoperative JJ cord-015369-72cjogxz 3042 17 pain pain NN cord-015369-72cjogxz 3042 18 , , , cord-015369-72cjogxz 3042 19 wound wound NN cord-015369-72cjogxz 3042 20 infection infection NN cord-015369-72cjogxz 3042 21 , , , cord-015369-72cjogxz 3042 22 risk risk NN cord-015369-72cjogxz 3042 23 of of IN cord-015369-72cjogxz 3042 24 hernia hernia NN cord-015369-72cjogxz 3042 25 and and CC cord-015369-72cjogxz 3042 26 hospital hospital NN cord-015369-72cjogxz 3042 27 stay stay NN cord-015369-72cjogxz 3042 28 . . . cord-015369-72cjogxz 3043 1 We -PRON- PRP cord-015369-72cjogxz 3043 2 report report VBP cord-015369-72cjogxz 3043 3 the the DT cord-015369-72cjogxz 3043 4 first first JJ cord-015369-72cjogxz 3043 5 results result NNS cord-015369-72cjogxz 3043 6 of of IN cord-015369-72cjogxz 3043 7 transvaginal transvaginal JJ cord-015369-72cjogxz 3043 8 Hybrid Hybrid NNP cord-015369-72cjogxz 3043 9 - - HYPH cord-015369-72cjogxz 3043 10 NOTES note NNS cord-015369-72cjogxz 3043 11 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 3043 12 in in IN cord-015369-72cjogxz 3043 13 Switzerland Switzerland NNP cord-015369-72cjogxz 3043 14 . . . cord-015369-72cjogxz 3044 1 Methods method NNS cord-015369-72cjogxz 3044 2 . . . cord-015369-72cjogxz 3045 1 From from IN cord-015369-72cjogxz 3045 2 July July NNP cord-015369-72cjogxz 3045 3 2008 2008 CD cord-015369-72cjogxz 3045 4 to to IN cord-015369-72cjogxz 3045 5 December December NNP cord-015369-72cjogxz 3045 6 2008 2008 CD cord-015369-72cjogxz 3045 7 , , , cord-015369-72cjogxz 3045 8 5 5 CD cord-015369-72cjogxz 3045 9 women woman NNS cord-015369-72cjogxz 3045 10 were be VBD cord-015369-72cjogxz 3045 11 treated treat VBN cord-015369-72cjogxz 3045 12 by by IN cord-015369-72cjogxz 3045 13 transvaginal transvaginal JJ cord-015369-72cjogxz 3045 14 Hybrid Hybrid NNP cord-015369-72cjogxz 3045 15 - - HYPH cord-015369-72cjogxz 3045 16 NOTES note NNS cord-015369-72cjogxz 3045 17 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 3045 18 . . . cord-015369-72cjogxz 3046 1 Pneumoperitoneum Pneumoperitoneum NNP cord-015369-72cjogxz 3046 2 was be VBD cord-015369-72cjogxz 3046 3 created create VBN cord-015369-72cjogxz 3046 4 through through IN cord-015369-72cjogxz 3046 5 a a DT cord-015369-72cjogxz 3046 6 5 5 CD cord-015369-72cjogxz 3046 7 mm mm NN cord-015369-72cjogxz 3046 8 incision incision NN cord-015369-72cjogxz 3046 9 in in IN cord-015369-72cjogxz 3046 10 the the DT cord-015369-72cjogxz 3046 11 umbilicus umbilicus NN cord-015369-72cjogxz 3046 12 . . . cord-015369-72cjogxz 3047 1 Two two CD cord-015369-72cjogxz 3047 2 rigid rigid JJ cord-015369-72cjogxz 3047 3 trocars trocar NNS cord-015369-72cjogxz 3047 4 ( ( -LRB- cord-015369-72cjogxz 3047 5 12 12 CD cord-015369-72cjogxz 3047 6 mm mm NNS cord-015369-72cjogxz 3047 7 and and CC cord-015369-72cjogxz 3047 8 5 5 CD cord-015369-72cjogxz 3047 9 mm mm NNS cord-015369-72cjogxz 3047 10 ) ) -RRB- cord-015369-72cjogxz 3047 11 were be VBD cord-015369-72cjogxz 3047 12 inserted insert VBN cord-015369-72cjogxz 3047 13 in in IN cord-015369-72cjogxz 3047 14 the the DT cord-015369-72cjogxz 3047 15 posterior posterior JJ cord-015369-72cjogxz 3047 16 fornix fornix NN cord-015369-72cjogxz 3047 17 of of IN cord-015369-72cjogxz 3047 18 the the DT cord-015369-72cjogxz 3047 19 vagina vagina NN cord-015369-72cjogxz 3047 20 . . . cord-015369-72cjogxz 3048 1 Patient Patient NNP cord-015369-72cjogxz 3048 2 data datum NNS cord-015369-72cjogxz 3048 3 , , , cord-015369-72cjogxz 3048 4 operative operative JJ cord-015369-72cjogxz 3048 5 time time NN cord-015369-72cjogxz 3048 6 , , , cord-015369-72cjogxz 3048 7 complications complication NNS cord-015369-72cjogxz 3048 8 and and CC cord-015369-72cjogxz 3048 9 postoperative postoperative JJ cord-015369-72cjogxz 3048 10 course course NN cord-015369-72cjogxz 3048 11 were be VBD cord-015369-72cjogxz 3048 12 recorded record VBN cord-015369-72cjogxz 3048 13 prospectively prospectively RB cord-015369-72cjogxz 3048 14 in in IN cord-015369-72cjogxz 3048 15 each each DT cord-015369-72cjogxz 3048 16 patient patient NN cord-015369-72cjogxz 3048 17 . . . cord-015369-72cjogxz 3049 1 Results result NNS cord-015369-72cjogxz 3049 2 . . . cord-015369-72cjogxz 3050 1 The the DT cord-015369-72cjogxz 3050 2 average average JJ cord-015369-72cjogxz 3050 3 age age NN cord-015369-72cjogxz 3050 4 of of IN cord-015369-72cjogxz 3050 5 the the DT cord-015369-72cjogxz 3050 6 5 5 CD cord-015369-72cjogxz 3050 7 patients patient NNS cord-015369-72cjogxz 3050 8 was be VBD cord-015369-72cjogxz 3050 9 34.6 34.6 CD cord-015369-72cjogxz 3050 10 years year NNS cord-015369-72cjogxz 3050 11 ( ( -LRB- cord-015369-72cjogxz 3050 12 19 19 CD cord-015369-72cjogxz 3050 13 - - SYM cord-015369-72cjogxz 3050 14 44 44 CD cord-015369-72cjogxz 3050 15 years year NNS cord-015369-72cjogxz 3050 16 ) ) -RRB- cord-015369-72cjogxz 3050 17 and and CC cord-015369-72cjogxz 3050 18 the the DT cord-015369-72cjogxz 3050 19 mean mean JJ cord-015369-72cjogxz 3050 20 body body NNP cord-015369-72cjogxz 3050 21 mass mass NNP cord-015369-72cjogxz 3050 22 index index NN cord-015369-72cjogxz 3050 23 was be VBD cord-015369-72cjogxz 3050 24 24.8 24.8 CD cord-015369-72cjogxz 3050 25 kg kg NNS cord-015369-72cjogxz 3050 26 / / SYM cord-015369-72cjogxz 3050 27 m m NN cord-015369-72cjogxz 3050 28 2 2 CD cord-015369-72cjogxz 3050 29 . . . cord-015369-72cjogxz 3051 1 All all DT cord-015369-72cjogxz 3051 2 operations operation NNS cord-015369-72cjogxz 3051 3 were be VBD cord-015369-72cjogxz 3051 4 performed perform VBN cord-015369-72cjogxz 3051 5 without without IN cord-015369-72cjogxz 3051 6 intraoperative intraoperative JJ cord-015369-72cjogxz 3051 7 complications complication NNS cord-015369-72cjogxz 3051 8 . . . cord-015369-72cjogxz 3052 1 The the DT cord-015369-72cjogxz 3052 2 mean mean JJ cord-015369-72cjogxz 3052 3 operative operative JJ cord-015369-72cjogxz 3052 4 time time NN cord-015369-72cjogxz 3052 5 was be VBD cord-015369-72cjogxz 3052 6 79 79 CD cord-015369-72cjogxz 3052 7 min min NN cord-015369-72cjogxz 3052 8 ( ( -LRB- cord-015369-72cjogxz 3052 9 65 65 CD cord-015369-72cjogxz 3052 10 - - SYM cord-015369-72cjogxz 3052 11 88 88 CD cord-015369-72cjogxz 3052 12 min min NN cord-015369-72cjogxz 3052 13 ) ) -RRB- cord-015369-72cjogxz 3052 14 . . . cord-015369-72cjogxz 3053 1 The the DT cord-015369-72cjogxz 3053 2 mean mean JJ cord-015369-72cjogxz 3053 3 hospital hospital NN cord-015369-72cjogxz 3053 4 stay stay NN cord-015369-72cjogxz 3053 5 was be VBD cord-015369-72cjogxz 3053 6 2.6 2.6 CD cord-015369-72cjogxz 3053 7 days day NNS cord-015369-72cjogxz 3053 8 ( ( -LRB- cord-015369-72cjogxz 3053 9 2 2 CD cord-015369-72cjogxz 3053 10 - - SYM cord-015369-72cjogxz 3053 11 3 3 CD cord-015369-72cjogxz 3053 12 days day NNS cord-015369-72cjogxz 3053 13 ) ) -RRB- cord-015369-72cjogxz 3053 14 . . . cord-015369-72cjogxz 3054 1 Non non JJ cord-015369-72cjogxz 3054 2 steroidal steroidal JJ cord-015369-72cjogxz 3054 3 antiinflammatory antiinflammatory JJ cord-015369-72cjogxz 3054 4 drugs drug NNS cord-015369-72cjogxz 3054 5 and and CC cord-015369-72cjogxz 3054 6 paracetamol paracetamol JJ cord-015369-72cjogxz 3054 7 or or CC cord-015369-72cjogxz 3054 8 metamizol metamizol NNP cord-015369-72cjogxz 3054 9 were be VBD cord-015369-72cjogxz 3054 10 administered administer VBN cord-015369-72cjogxz 3054 11 for for IN cord-015369-72cjogxz 3054 12 analgesia analgesia NN cord-015369-72cjogxz 3054 13 . . . cord-015369-72cjogxz 3055 1 The the DT cord-015369-72cjogxz 3055 2 postoperative postoperative JJ cord-015369-72cjogxz 3055 3 course course NN cord-015369-72cjogxz 3055 4 was be VBD cord-015369-72cjogxz 3055 5 uneventful uneventful JJ cord-015369-72cjogxz 3055 6 . . . cord-015369-72cjogxz 3056 1 No no DT cord-015369-72cjogxz 3056 2 complications complication NNS cord-015369-72cjogxz 3056 3 were be VBD cord-015369-72cjogxz 3056 4 recorded record VBN cord-015369-72cjogxz 3056 5 during during IN cord-015369-72cjogxz 3056 6 the the DT cord-015369-72cjogxz 3056 7 further further JJ cord-015369-72cjogxz 3056 8 postoperative postoperative JJ cord-015369-72cjogxz 3056 9 follow follow NN cord-015369-72cjogxz 3056 10 - - HYPH cord-015369-72cjogxz 3056 11 up up NN cord-015369-72cjogxz 3056 12 after after IN cord-015369-72cjogxz 3056 13 4 4 CD cord-015369-72cjogxz 3056 14 weeks week NNS cord-015369-72cjogxz 3056 15 . . . cord-015369-72cjogxz 3057 1 Conclusions conclusion NNS cord-015369-72cjogxz 3057 2 . . . cord-015369-72cjogxz 3058 1 The the DT cord-015369-72cjogxz 3058 2 transvaginal transvaginal JJ cord-015369-72cjogxz 3058 3 Hybrid Hybrid NNP cord-015369-72cjogxz 3058 4 - - HYPH cord-015369-72cjogxz 3058 5 NOTES note NNS cord-015369-72cjogxz 3058 6 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 3058 7 is be VBZ cord-015369-72cjogxz 3058 8 a a DT cord-015369-72cjogxz 3058 9 feasible feasible JJ cord-015369-72cjogxz 3058 10 and and CC cord-015369-72cjogxz 3058 11 probably probably RB cord-015369-72cjogxz 3058 12 safe safe JJ cord-015369-72cjogxz 3058 13 procedure procedure NN cord-015369-72cjogxz 3058 14 . . . cord-015369-72cjogxz 3059 1 Operative operative JJ cord-015369-72cjogxz 3059 2 time time NN cord-015369-72cjogxz 3059 3 was be VBD cord-015369-72cjogxz 3059 4 despite despite IN cord-015369-72cjogxz 3059 5 of of IN cord-015369-72cjogxz 3059 6 any any DT cord-015369-72cjogxz 3059 7 expected expect VBN cord-015369-72cjogxz 3059 8 learning learn VBG cord-015369-72cjogxz 3059 9 courve courve JJ cord-015369-72cjogxz 3059 10 effects effect NNS cord-015369-72cjogxz 3059 11 not not RB cord-015369-72cjogxz 3059 12 significantly significantly RB cord-015369-72cjogxz 3059 13 longer long RBR cord-015369-72cjogxz 3059 14 than than IN cord-015369-72cjogxz 3059 15 in in IN cord-015369-72cjogxz 3059 16 laparoscopic laparoscopic JJ cord-015369-72cjogxz 3059 17 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 3059 18 . . . cord-015369-72cjogxz 3060 1 The the DT cord-015369-72cjogxz 3060 2 posterior posterior JJ cord-015369-72cjogxz 3060 3 colpotomy colpotomy NN cord-015369-72cjogxz 3060 4 is be VBZ cord-015369-72cjogxz 3060 5 a a DT cord-015369-72cjogxz 3060 6 simple simple JJ cord-015369-72cjogxz 3060 7 approach approach NN cord-015369-72cjogxz 3060 8 to to IN cord-015369-72cjogxz 3060 9 the the DT cord-015369-72cjogxz 3060 10 abdominal abdominal JJ cord-015369-72cjogxz 3060 11 cavity cavity NN cord-015369-72cjogxz 3060 12 and and CC cord-015369-72cjogxz 3060 13 wound wound JJ cord-015369-72cjogxz 3060 14 healing healing NN cord-015369-72cjogxz 3060 15 is be VBZ cord-015369-72cjogxz 3060 16 very very RB cord-015369-72cjogxz 3060 17 rapid rapid JJ cord-015369-72cjogxz 3060 18 . . . cord-015369-72cjogxz 3061 1 Using use VBG cord-015369-72cjogxz 3061 2 rigid rigid JJ cord-015369-72cjogxz 3061 3 instruments instrument NNS cord-015369-72cjogxz 3061 4 and and CC cord-015369-72cjogxz 3061 5 techniques technique NNS cord-015369-72cjogxz 3061 6 wellknown wellknown JJ cord-015369-72cjogxz 3061 7 for for IN cord-015369-72cjogxz 3061 8 laparoscopic laparoscopic JJ cord-015369-72cjogxz 3061 9 techniques technique NNS cord-015369-72cjogxz 3061 10 transvaginal transvaginal IN cord-015369-72cjogxz 3061 11 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 3061 12 seems seem VBZ cord-015369-72cjogxz 3061 13 feasible feasible JJ cord-015369-72cjogxz 3061 14 with with IN cord-015369-72cjogxz 3061 15 low low JJ cord-015369-72cjogxz 3061 16 operative operative JJ cord-015369-72cjogxz 3061 17 risk risk NN cord-015369-72cjogxz 3061 18 . . . cord-015369-72cjogxz 3062 1 Background background NN cord-015369-72cjogxz 3062 2 . . . cord-015369-72cjogxz 3063 1 The the DT cord-015369-72cjogxz 3063 2 latency latency NN cord-015369-72cjogxz 3063 3 time time NN cord-015369-72cjogxz 3063 4 to to TO cord-015369-72cjogxz 3063 5 develop develop VB cord-015369-72cjogxz 3063 6 colonic colonic JJ cord-015369-72cjogxz 3063 7 carcinoma carcinoma NN cord-015369-72cjogxz 3063 8 in in IN cord-015369-72cjogxz 3063 9 patients patient NNS cord-015369-72cjogxz 3063 10 with with IN cord-015369-72cjogxz 3063 11 uretersigmoidostomy uretersigmoidostomy NN cord-015369-72cjogxz 3063 12 ( ( -LRB- cord-015369-72cjogxz 3063 13 URSIG URSIG NNP cord-015369-72cjogxz 3063 14 ) ) -RRB- cord-015369-72cjogxz 3063 15 is be VBZ cord-015369-72cjogxz 3063 16 usually usually RB cord-015369-72cjogxz 3063 17 more more JJR cord-015369-72cjogxz 3063 18 than than IN cord-015369-72cjogxz 3063 19 ten ten CD cord-015369-72cjogxz 3063 20 years year NNS cord-015369-72cjogxz 3063 21 . . . cord-015369-72cjogxz 3064 1 We -PRON- PRP cord-015369-72cjogxz 3064 2 present present VBP cord-015369-72cjogxz 3064 3 a a DT cord-015369-72cjogxz 3064 4 case case NN cord-015369-72cjogxz 3064 5 of of IN cord-015369-72cjogxz 3064 6 carcinoma carcinoma NN cord-015369-72cjogxz 3064 7 in in IN cord-015369-72cjogxz 3064 8 - - HYPH cord-015369-72cjogxz 3064 9 situ situ NN cord-015369-72cjogxz 3064 10 of of IN cord-015369-72cjogxz 3064 11 the the DT cord-015369-72cjogxz 3064 12 colon colon NN cord-015369-72cjogxz 3064 13 in in IN cord-015369-72cjogxz 3064 14 which which WDT cord-015369-72cjogxz 3064 15 a a DT cord-015369-72cjogxz 3064 16 URSIG URSIG NNP cord-015369-72cjogxz 3064 17 was be VBD cord-015369-72cjogxz 3064 18 present present JJ cord-015369-72cjogxz 3064 19 less less JJR cord-015369-72cjogxz 3064 20 than than IN cord-015369-72cjogxz 3064 21 six six CD cord-015369-72cjogxz 3064 22 months month NNS cord-015369-72cjogxz 3064 23 . . . cord-015369-72cjogxz 3065 1 Method method NN cord-015369-72cjogxz 3065 2 . . . cord-015369-72cjogxz 3066 1 Retrospective retrospective JJ cord-015369-72cjogxz 3066 2 chart chart NN cord-015369-72cjogxz 3066 3 review review NN cord-015369-72cjogxz 3066 4 . . . cord-015369-72cjogxz 3067 1 Case case NN cord-015369-72cjogxz 3067 2 report report NN cord-015369-72cjogxz 3067 3 . . . cord-015369-72cjogxz 3068 1 An an DT cord-015369-72cjogxz 3068 2 eighteen eighteen CD cord-015369-72cjogxz 3068 3 - - HYPH cord-015369-72cjogxz 3068 4 year year NN cord-015369-72cjogxz 3068 5 - - HYPH cord-015369-72cjogxz 3068 6 old old JJ cord-015369-72cjogxz 3068 7 male male NN cord-015369-72cjogxz 3068 8 born bear VBN cord-015369-72cjogxz 3068 9 with with IN cord-015369-72cjogxz 3068 10 bladder bladder NN cord-015369-72cjogxz 3068 11 exstrophy exstrophy NNP cord-015369-72cjogxz 3068 12 underwent undergo VBD cord-015369-72cjogxz 3068 13 a a DT cord-015369-72cjogxz 3068 14 URSIG URSIG NNP cord-015369-72cjogxz 3068 15 at at IN cord-015369-72cjogxz 3068 16 age age NN cord-015369-72cjogxz 3068 17 of of IN cord-015369-72cjogxz 3068 18 4 4 CD cord-015369-72cjogxz 3068 19 months month NNS cord-015369-72cjogxz 3068 20 after after IN cord-015369-72cjogxz 3068 21 a a DT cord-015369-72cjogxz 3068 22 failed fail VBN cord-015369-72cjogxz 3068 23 bladder bladder NN cord-015369-72cjogxz 3068 24 closure closure NN cord-015369-72cjogxz 3068 25 . . . cord-015369-72cjogxz 3069 1 Four four CD cord-015369-72cjogxz 3069 2 months month NNS cord-015369-72cjogxz 3069 3 later later RB cord-015369-72cjogxz 3069 4 the the DT cord-015369-72cjogxz 3069 5 URSIG URSIG NNP cord-015369-72cjogxz 3069 6 was be VBD cord-015369-72cjogxz 3069 7 converted convert VBN cord-015369-72cjogxz 3069 8 to to IN cord-015369-72cjogxz 3069 9 an an DT cord-015369-72cjogxz 3069 10 incontinent incontinent JJ cord-015369-72cjogxz 3069 11 uretero uretero NN cord-015369-72cjogxz 3069 12 - - HYPH cord-015369-72cjogxz 3069 13 ileostomy ileostomy NN cord-015369-72cjogxz 3069 14 . . . cord-015369-72cjogxz 3070 1 At at IN cord-015369-72cjogxz 3070 2 eighteen eighteen CD cord-015369-72cjogxz 3070 3 years year NNS cord-015369-72cjogxz 3070 4 of of IN cord-015369-72cjogxz 3070 5 age age NN cord-015369-72cjogxz 3070 6 during during IN cord-015369-72cjogxz 3070 7 an an DT cord-015369-72cjogxz 3070 8 operation operation NN cord-015369-72cjogxz 3070 9 to to TO cord-015369-72cjogxz 3070 10 construct construct VB cord-015369-72cjogxz 3070 11 a a DT cord-015369-72cjogxz 3070 12 continent continent NN cord-015369-72cjogxz 3070 13 reservoir reservoir NN cord-015369-72cjogxz 3070 14 carcinoma carcinoma NN cord-015369-72cjogxz 3070 15 in in IN cord-015369-72cjogxz 3070 16 - - HYPH cord-015369-72cjogxz 3070 17 situ situ NN cord-015369-72cjogxz 3070 18 of of IN cord-015369-72cjogxz 3070 19 the the DT cord-015369-72cjogxz 3070 20 rectosigmoid rectosigmoid NN cord-015369-72cjogxz 3070 21 was be VBD cord-015369-72cjogxz 3070 22 incidentally incidentally RB cord-015369-72cjogxz 3070 23 discovered discover VBN cord-015369-72cjogxz 3070 24 . . . cord-015369-72cjogxz 3071 1 The the DT cord-015369-72cjogxz 3071 2 involved involved JJ cord-015369-72cjogxz 3071 3 bowel bowel NN cord-015369-72cjogxz 3071 4 was be VBD cord-015369-72cjogxz 3071 5 resected resect VBN cord-015369-72cjogxz 3071 6 and and CC cord-015369-72cjogxz 3071 7 a a DT cord-015369-72cjogxz 3071 8 continent continent NN cord-015369-72cjogxz 3071 9 reservoir reservoir NN cord-015369-72cjogxz 3071 10 with with IN cord-015369-72cjogxz 3071 11 the the DT cord-015369-72cjogxz 3071 12 ileal ileal JJ cord-015369-72cjogxz 3071 13 segment segment NN cord-015369-72cjogxz 3071 14 and and CC cord-015369-72cjogxz 3071 15 descending descend VBG cord-015369-72cjogxz 3071 16 colon colon NN cord-015369-72cjogxz 3071 17 was be VBD cord-015369-72cjogxz 3071 18 created create VBN cord-015369-72cjogxz 3071 19 . . . cord-015369-72cjogxz 3072 1 The the DT cord-015369-72cjogxz 3072 2 patient patient NN cord-015369-72cjogxz 3072 3 remains remain VBZ cord-015369-72cjogxz 3072 4 disease disease NN cord-015369-72cjogxz 3072 5 free free JJ cord-015369-72cjogxz 3072 6 for for IN cord-015369-72cjogxz 3072 7 the the DT cord-015369-72cjogxz 3072 8 next next JJ cord-015369-72cjogxz 3072 9 8 8 CD cord-015369-72cjogxz 3072 10 years year NNS cord-015369-72cjogxz 3072 11 . . . cord-015369-72cjogxz 3073 1 Conclusions conclusion NNS cord-015369-72cjogxz 3073 2 . . . cord-015369-72cjogxz 3074 1 Colonic colonic JJ cord-015369-72cjogxz 3074 2 carcinoma carcinoma NN cord-015369-72cjogxz 3074 3 can can MD cord-015369-72cjogxz 3074 4 develop develop VB cord-015369-72cjogxz 3074 5 even even RB cord-015369-72cjogxz 3074 6 after after IN cord-015369-72cjogxz 3074 7 very very RB cord-015369-72cjogxz 3074 8 short short JJ cord-015369-72cjogxz 3074 9 time time NN cord-015369-72cjogxz 3074 10 with with IN cord-015369-72cjogxz 3074 11 a a DT cord-015369-72cjogxz 3074 12 URSIG URSIG NNP cord-015369-72cjogxz 3074 13 . . . cord-015369-72cjogxz 3075 1 When when WRB cord-015369-72cjogxz 3075 2 URSIG URSIG NNP cord-015369-72cjogxz 3075 3 is be VBZ cord-015369-72cjogxz 3075 4 taken take VBN cord-015369-72cjogxz 3075 5 down down RP cord-015369-72cjogxz 3075 6 , , , cord-015369-72cjogxz 3075 7 the the DT cord-015369-72cjogxz 3075 8 involved involve VBN cord-015369-72cjogxz 3075 9 colonic colonic JJ cord-015369-72cjogxz 3075 10 segment segment NN cord-015369-72cjogxz 3075 11 should should MD cord-015369-72cjogxz 3075 12 be be VB cord-015369-72cjogxz 3075 13 removed remove VBN cord-015369-72cjogxz 3075 14 . . . cord-015369-72cjogxz 3076 1 Adrenal adrenal JJ cord-015369-72cjogxz 3076 2 tumors tumor NNS cord-015369-72cjogxz 3076 3 in in IN cord-015369-72cjogxz 3076 4 children child NNS cord-015369-72cjogxz 3076 5 A. a. NN cord-015369-72cjogxz 3076 6 Pereyaslov Pereyaslov NNP cord-015369-72cjogxz 3076 7 1 1 CD cord-015369-72cjogxz 3076 8 , , , cord-015369-72cjogxz 3076 9 A. A. NNP cord-015369-72cjogxz 3076 10 Dvorakevich Dvorakevich NNP cord-015369-72cjogxz 3076 11 1 1 CD cord-015369-72cjogxz 3076 12 , , , cord-015369-72cjogxz 3076 13 L. L. NNP cord-015369-72cjogxz 3076 14 Burda Burda NNP cord-015369-72cjogxz 3076 15 2 2 CD cord-015369-72cjogxz 3076 16 1 1 CD cord-015369-72cjogxz 3076 17 Medical Medical NNP cord-015369-72cjogxz 3076 18 University University NNP cord-015369-72cjogxz 3076 19 , , , cord-015369-72cjogxz 3076 20 Lviv Lviv NNP cord-015369-72cjogxz 3076 21 , , , cord-015369-72cjogxz 3076 22 Ukraine Ukraine NNP cord-015369-72cjogxz 3076 23 ; ; : cord-015369-72cjogxz 3076 24 2 2 CD cord-015369-72cjogxz 3076 25 Regional Regional NNP cord-015369-72cjogxz 3076 26 Children Children NNPS cord-015369-72cjogxz 3076 27 Hospital Hospital NNP cord-015369-72cjogxz 3076 28 , , , cord-015369-72cjogxz 3076 29 Lviv Lviv NNP cord-015369-72cjogxz 3076 30 , , , cord-015369-72cjogxz 3076 31 Ukraine Ukraine NNP cord-015369-72cjogxz 3076 32 Adrenal adrenal JJ cord-015369-72cjogxz 3076 33 tumors tumor NNS cord-015369-72cjogxz 3076 34 are be VBP cord-015369-72cjogxz 3076 35 the the DT cord-015369-72cjogxz 3076 36 rare rare JJ cord-015369-72cjogxz 3076 37 cause cause NN cord-015369-72cjogxz 3076 38 of of IN cord-015369-72cjogxz 3076 39 arterial arterial JJ cord-015369-72cjogxz 3076 40 hypertension hypertension NN cord-015369-72cjogxz 3076 41 in in IN cord-015369-72cjogxz 3076 42 children child NNS cord-015369-72cjogxz 3076 43 . . . cord-015369-72cjogxz 3077 1 Prolonged prolonged JJ cord-015369-72cjogxz 3077 2 period period NN cord-015369-72cjogxz 3077 3 of of IN cord-015369-72cjogxz 3077 4 diagnosis diagnosis NN cord-015369-72cjogxz 3077 5 determines determine VBZ cord-015369-72cjogxz 3077 6 inadequate inadequate JJ cord-015369-72cjogxz 3077 7 treatment treatment NN cord-015369-72cjogxz 3077 8 of of IN cord-015369-72cjogxz 3077 9 arterial arterial JJ cord-015369-72cjogxz 3077 10 hypertension hypertension NN cord-015369-72cjogxz 3077 11 with with IN cord-015369-72cjogxz 3077 12 the the DT cord-015369-72cjogxz 3077 13 development development NN cord-015369-72cjogxz 3077 14 of of IN cord-015369-72cjogxz 3077 15 lifetreating lifetreate VBG cord-015369-72cjogxz 3077 16 complications complication NNS cord-015369-72cjogxz 3077 17 . . . cord-015369-72cjogxz 3078 1 In in IN cord-015369-72cjogxz 3078 2 this this DT cord-015369-72cjogxz 3078 3 study study NN cord-015369-72cjogxz 3078 4 summarized summarize VBD cord-015369-72cjogxz 3078 5 results result NNS cord-015369-72cjogxz 3078 6 of of IN cord-015369-72cjogxz 3078 7 treatment treatment NN cord-015369-72cjogxz 3078 8 39 39 CD cord-015369-72cjogxz 3078 9 children child NNS cord-015369-72cjogxz 3078 10 with with IN cord-015369-72cjogxz 3078 11 adrenal adrenal JJ cord-015369-72cjogxz 3078 12 tumors tumor NNS cord-015369-72cjogxz 3078 13 during during IN cord-015369-72cjogxz 3078 14 20-years 20-years CD cord-015369-72cjogxz 3078 15 period period NN cord-015369-72cjogxz 3078 16 . . . cord-015369-72cjogxz 3079 1 There there EX cord-015369-72cjogxz 3079 2 were be VBD cord-015369-72cjogxz 3079 3 34 34 CD cord-015369-72cjogxz 3079 4 ( ( -LRB- cord-015369-72cjogxz 3079 5 87.2 87.2 CD cord-015369-72cjogxz 3079 6 % % NN cord-015369-72cjogxz 3079 7 ) ) -RRB- cord-015369-72cjogxz 3079 8 children child NNS cord-015369-72cjogxz 3079 9 with with IN cord-015369-72cjogxz 3079 10 benign benign JJ cord-015369-72cjogxz 3079 11 adrenal adrenal JJ cord-015369-72cjogxz 3079 12 tumors tumor NNS cord-015369-72cjogxz 3079 13 , , , cord-015369-72cjogxz 3079 14 including include VBG cord-015369-72cjogxz 3079 15 30 30 CD cord-015369-72cjogxz 3079 16 children child NNS cord-015369-72cjogxz 3079 17 with with IN cord-015369-72cjogxz 3079 18 hormonally hormonally RB cord-015369-72cjogxz 3079 19 active active JJ cord-015369-72cjogxz 3079 20 ( ( -LRB- cord-015369-72cjogxz 3079 21 Cushing Cushing NNP cord-015369-72cjogxz 3079 22 's 's POS cord-015369-72cjogxz 3079 23 syndrome syndrome NN cord-015369-72cjogxz 3079 24 -13 -13 NNS cord-015369-72cjogxz 3079 25 , , , cord-015369-72cjogxz 3079 26 virilizing virilize VBG cord-015369-72cjogxz 3079 27 tumor tumor NN cord-015369-72cjogxz 3079 28 -3 -3 NNP cord-015369-72cjogxz 3079 29 , , , cord-015369-72cjogxz 3079 30 feminizing feminize VBG cord-015369-72cjogxz 3079 31 tumor tumor NN cord-015369-72cjogxz 3079 32 -2 -2 NNP cord-015369-72cjogxz 3079 33 , , , cord-015369-72cjogxz 3079 34 pheochromocytoma pheochromocytoma NN cord-015369-72cjogxz 3080 1 -9 -9 NNP cord-015369-72cjogxz 3080 2 , , , cord-015369-72cjogxz 3080 3 Conn Conn NNP cord-015369-72cjogxz 3080 4 syndrome syndrome NN cord-015369-72cjogxz 3080 5 -1 -1 NN cord-015369-72cjogxz 3080 6 ) ) -RRB- cord-015369-72cjogxz 3080 7 and and CC cord-015369-72cjogxz 3080 8 4 4 CD cord-015369-72cjogxz 3080 9 -with -with CD cord-015369-72cjogxz 3080 10 non non JJ cord-015369-72cjogxz 3080 11 - - JJ cord-015369-72cjogxz 3080 12 functioning functioning JJ cord-015369-72cjogxz 3080 13 tumors tumor NNS cord-015369-72cjogxz 3080 14 . . . cord-015369-72cjogxz 3081 1 Five five CD cord-015369-72cjogxz 3081 2 ( ( -LRB- cord-015369-72cjogxz 3081 3 12.8 12.8 CD cord-015369-72cjogxz 3081 4 % % NN cord-015369-72cjogxz 3081 5 ) ) -RRB- cord-015369-72cjogxz 3081 6 patients patient NNS cord-015369-72cjogxz 3081 7 had have VBD cord-015369-72cjogxz 3081 8 malignant malignant JJ cord-015369-72cjogxz 3081 9 adrenal adrenal JJ cord-015369-72cjogxz 3081 10 tumors tumor NNS cord-015369-72cjogxz 3081 11 : : : cord-015369-72cjogxz 3081 12 3 3 CD cord-015369-72cjogxz 3081 13 patients patient NNS cord-015369-72cjogxz 3081 14 had have VBD cord-015369-72cjogxz 3081 15 adrenocortical adrenocortical JJ cord-015369-72cjogxz 3081 16 cancer cancer NN cord-015369-72cjogxz 3081 17 , , , cord-015369-72cjogxz 3081 18 one one CD cord-015369-72cjogxz 3081 19 -malignant -malignant HYPH cord-015369-72cjogxz 3081 20 corticochromoblastoma corticochromoblastoma NN cord-015369-72cjogxz 3081 21 , , , cord-015369-72cjogxz 3081 22 and and CC cord-015369-72cjogxz 3081 23 one one CD cord-015369-72cjogxz 3081 24 -chromoandroblastoma -chromoandroblastoma NN cord-015369-72cjogxz 3081 25 . . . cord-015369-72cjogxz 3082 1 Adrenalectomy Adrenalectomy NNP cord-015369-72cjogxz 3082 2 was be VBD cord-015369-72cjogxz 3082 3 performed perform VBN cord-015369-72cjogxz 3082 4 in in IN cord-015369-72cjogxz 3082 5 37 37 CD cord-015369-72cjogxz 3082 6 ( ( -LRB- cord-015369-72cjogxz 3082 7 84.9 84.9 CD cord-015369-72cjogxz 3082 8 % % NN cord-015369-72cjogxz 3082 9 ) ) -RRB- cord-015369-72cjogxz 3082 10 patients patient NNS cord-015369-72cjogxz 3082 11 . . . cord-015369-72cjogxz 3083 1 Conventional conventional JJ cord-015369-72cjogxz 3083 2 lumbotomy lumbotomy NN cord-015369-72cjogxz 3083 3 was be VBD cord-015369-72cjogxz 3083 4 applied apply VBN cord-015369-72cjogxz 3083 5 in in IN cord-015369-72cjogxz 3083 6 30 30 CD cord-015369-72cjogxz 3083 7 ( ( -LRB- cord-015369-72cjogxz 3083 8 81.8 81.8 CD cord-015369-72cjogxz 3083 9 % % NN cord-015369-72cjogxz 3083 10 ) ) -RRB- cord-015369-72cjogxz 3083 11 patients patient NNS cord-015369-72cjogxz 3083 12 and and CC cord-015369-72cjogxz 3083 13 in in IN cord-015369-72cjogxz 3083 14 7 7 CD cord-015369-72cjogxz 3083 15 ( ( -LRB- cord-015369-72cjogxz 3083 16 18.2 18.2 CD cord-015369-72cjogxz 3083 17 % % NN cord-015369-72cjogxz 3083 18 ) ) -RRB- cord-015369-72cjogxz 3084 1 -laparoscopic -laparoscopic NNP cord-015369-72cjogxz 3084 2 adrenalectomy adrenalectomy NNP cord-015369-72cjogxz 3084 3 . . . cord-015369-72cjogxz 3085 1 Laparoscopic laparoscopic JJ cord-015369-72cjogxz 3085 2 removing remove VBG cord-015369-72cjogxz 3085 3 of of IN cord-015369-72cjogxz 3085 4 adrenal adrenal JJ cord-015369-72cjogxz 3085 5 tumors tumor NNS cord-015369-72cjogxz 3085 6 was be VBD cord-015369-72cjogxz 3085 7 performed perform VBN cord-015369-72cjogxz 3085 8 in in IN cord-015369-72cjogxz 3085 9 3 3 CD cord-015369-72cjogxz 3085 10 children child NNS cord-015369-72cjogxz 3085 11 with with IN cord-015369-72cjogxz 3085 12 pheochromocytoma pheochromocytoma NN cord-015369-72cjogxz 3085 13 , , , cord-015369-72cjogxz 3085 14 in in IN cord-015369-72cjogxz 3085 15 3 3 CD cord-015369-72cjogxz 3085 16 -with -with CD cord-015369-72cjogxz 3085 17 adrenal adrenal JJ cord-015369-72cjogxz 3085 18 cyst cyst NN cord-015369-72cjogxz 3085 19 and and CC cord-015369-72cjogxz 3085 20 in in IN cord-015369-72cjogxz 3085 21 1 1 CD cord-015369-72cjogxz 3085 22 -with -with CD cord-015369-72cjogxz 3085 23 myelolipoma myelolipoma NNP cord-015369-72cjogxz 3085 24 . . . cord-015369-72cjogxz 3086 1 The the DT cord-015369-72cjogxz 3086 2 retroperitoneal retroperitoneal JJ cord-015369-72cjogxz 3086 3 approach approach NN cord-015369-72cjogxz 3086 4 was be VBD cord-015369-72cjogxz 3086 5 applied apply VBN cord-015369-72cjogxz 3086 6 in in IN cord-015369-72cjogxz 3086 7 5 5 CD cord-015369-72cjogxz 3086 8 patients patient NNS cord-015369-72cjogxz 3086 9 and and CC cord-015369-72cjogxz 3086 10 transperitoneal transperitoneal JJ cord-015369-72cjogxz 3086 11 -in -in SYM cord-015369-72cjogxz 3086 12 2 2 CD cord-015369-72cjogxz 3086 13 patients patient NNS cord-015369-72cjogxz 3086 14 . . . cord-015369-72cjogxz 3087 1 There there EX cord-015369-72cjogxz 3087 2 was be VBD cord-015369-72cjogxz 3087 3 no no DT cord-015369-72cjogxz 3087 4 conversion conversion NN cord-015369-72cjogxz 3087 5 during during IN cord-015369-72cjogxz 3087 6 laparoscopic laparoscopic JJ cord-015369-72cjogxz 3087 7 adrenalectomy adrenalectomy NNP cord-015369-72cjogxz 3087 8 . . . cord-015369-72cjogxz 3088 1 Two two CD cord-015369-72cjogxz 3088 2 ( ( -LRB- cord-015369-72cjogxz 3088 3 5.1 5.1 CD cord-015369-72cjogxz 3088 4 % % NN cord-015369-72cjogxz 3088 5 ) ) -RRB- cord-015369-72cjogxz 3088 6 children child NNS cord-015369-72cjogxz 3088 7 with with IN cord-015369-72cjogxz 3088 8 corticochromoblastoma corticochromoblastoma NNP cord-015369-72cjogxz 3088 9 and and CC cord-015369-72cjogxz 3088 10 chromoandroblastoma chromoandroblastoma NNP cord-015369-72cjogxz 3088 11 did do VBD cord-015369-72cjogxz 3088 12 not not RB cord-015369-72cjogxz 3088 13 operated operate VBN cord-015369-72cjogxz 3088 14 due due IN cord-015369-72cjogxz 3088 15 to to IN cord-015369-72cjogxz 3088 16 the the DT cord-015369-72cjogxz 3088 17 disseminated disseminate VBN cord-015369-72cjogxz 3088 18 metastasis metastasis NN cord-015369-72cjogxz 3088 19 at at IN cord-015369-72cjogxz 3088 20 the the DT cord-015369-72cjogxz 3088 21 time time NN cord-015369-72cjogxz 3088 22 of of IN cord-015369-72cjogxz 3088 23 admission admission NN cord-015369-72cjogxz 3088 24 and and CC cord-015369-72cjogxz 3088 25 they -PRON- PRP cord-015369-72cjogxz 3088 26 died die VBD cord-015369-72cjogxz 3088 27 at at IN cord-015369-72cjogxz 3088 28 the the DT cord-015369-72cjogxz 3088 29 follow follow NN cord-015369-72cjogxz 3088 30 - - HYPH cord-015369-72cjogxz 3088 31 up up NN cord-015369-72cjogxz 3088 32 . . . cord-015369-72cjogxz 3089 1 All all DT cord-015369-72cjogxz 3089 2 patients patient NNS cord-015369-72cjogxz 3089 3 who who WP cord-015369-72cjogxz 3089 4 underwent undergo VBD cord-015369-72cjogxz 3089 5 adrenalectomy adrenalectomy NNP cord-015369-72cjogxz 3089 6 were be VBD cord-015369-72cjogxz 3089 7 discharged discharge VBN cord-015369-72cjogxz 3089 8 with with IN cord-015369-72cjogxz 3089 9 normal normal JJ cord-015369-72cjogxz 3089 10 blood blood NN cord-015369-72cjogxz 3089 11 pressure pressure NN cord-015369-72cjogxz 3089 12 and and CC cord-015369-72cjogxz 3089 13 no no DT cord-015369-72cjogxz 3089 14 patient patient NN cord-015369-72cjogxz 3089 15 required require VBN cord-015369-72cjogxz 3089 16 adjuvant adjuvant NN cord-015369-72cjogxz 3089 17 therapy therapy NN cord-015369-72cjogxz 3089 18 . . . cord-015369-72cjogxz 3090 1 Surgery surgery NN cord-015369-72cjogxz 3090 2 remains remain VBZ cord-015369-72cjogxz 3090 3 the the DT cord-015369-72cjogxz 3090 4 method method NN cord-015369-72cjogxz 3090 5 of of IN cord-015369-72cjogxz 3090 6 choice choice NN cord-015369-72cjogxz 3090 7 in in IN cord-015369-72cjogxz 3090 8 the the DT cord-015369-72cjogxz 3090 9 management management NN cord-015369-72cjogxz 3090 10 of of IN cord-015369-72cjogxz 3090 11 children child NNS cord-015369-72cjogxz 3090 12 with with IN cord-015369-72cjogxz 3090 13 adrenal adrenal JJ cord-015369-72cjogxz 3090 14 tumors tumor NNS cord-015369-72cjogxz 3090 15 and and CC cord-015369-72cjogxz 3090 16 laparoscopic laparoscopic JJ cord-015369-72cjogxz 3090 17 adrenalectomy adrenalectomy NN cord-015369-72cjogxz 3090 18 may may NNP cord-015369-72cjogxz 3090 19 applied apply VBD cord-015369-72cjogxz 3090 20 in in IN cord-015369-72cjogxz 3090 21 patients patient NNS cord-015369-72cjogxz 3090 22 independently independently RB cord-015369-72cjogxz 3090 23 of of IN cord-015369-72cjogxz 3090 24 tumors tumor NNS cord-015369-72cjogxz 3090 25 ' ' POS cord-015369-72cjogxz 3090 26 functional functional JJ cord-015369-72cjogxz 3090 27 activity activity NN cord-015369-72cjogxz 3090 28 . . . cord-015369-72cjogxz 3091 1 Damage damage NN cord-015369-72cjogxz 3091 2 to to IN cord-015369-72cjogxz 3091 3 the the DT cord-015369-72cjogxz 3091 4 ureter ureter NN cord-015369-72cjogxz 3091 5 by by IN cord-015369-72cjogxz 3091 6 an an DT cord-015369-72cjogxz 3091 7 iatrogenic iatrogenic JJ cord-015369-72cjogxz 3091 8 injury injury NN cord-015369-72cjogxz 3091 9 is be VBZ cord-015369-72cjogxz 3091 10 a a DT cord-015369-72cjogxz 3091 11 devastating devastating JJ cord-015369-72cjogxz 3091 12 occurrence occurrence NN cord-015369-72cjogxz 3091 13 . . . cord-015369-72cjogxz 3092 1 Congenital congenital JJ cord-015369-72cjogxz 3092 2 ureteral ureteral JJ cord-015369-72cjogxz 3092 3 anomalies anomaly NNS cord-015369-72cjogxz 3092 4 present present VBP cord-015369-72cjogxz 3092 5 an an DT cord-015369-72cjogxz 3092 6 increased increase VBN cord-015369-72cjogxz 3092 7 risk risk NN cord-015369-72cjogxz 3092 8 of of IN cord-015369-72cjogxz 3092 9 injury injury NN cord-015369-72cjogxz 3092 10 . . . cord-015369-72cjogxz 3093 1 Case case NN cord-015369-72cjogxz 3093 2 report report NN cord-015369-72cjogxz 3093 3 . . . cord-015369-72cjogxz 3094 1 We -PRON- PRP cord-015369-72cjogxz 3094 2 report report VBP cord-015369-72cjogxz 3094 3 a a DT cord-015369-72cjogxz 3094 4 3-month 3-month CD cord-015369-72cjogxz 3094 5 - - HYPH cord-015369-72cjogxz 3094 6 old old JJ cord-015369-72cjogxz 3094 7 baby baby NN cord-015369-72cjogxz 3094 8 that that WDT cord-015369-72cjogxz 3094 9 underwent undergo VBD cord-015369-72cjogxz 3094 10 right right JJ cord-015369-72cjogxz 3094 11 nephrectomy nephrectomy NN cord-015369-72cjogxz 3094 12 for for IN cord-015369-72cjogxz 3094 13 a a DT cord-015369-72cjogxz 3094 14 multicystic multicystic JJ cord-015369-72cjogxz 3094 15 kidney kidney NN cord-015369-72cjogxz 3094 16 . . . cord-015369-72cjogxz 3095 1 The the DT cord-015369-72cjogxz 3095 2 left left JJ cord-015369-72cjogxz 3095 3 ureter ureter NN cord-015369-72cjogxz 3095 4 had have VBD cord-015369-72cjogxz 3095 5 been be VBN cord-015369-72cjogxz 3095 6 damaged damage VBN cord-015369-72cjogxz 3095 7 as as IN cord-015369-72cjogxz 3095 8 an an DT cord-015369-72cjogxz 3095 9 interlaced interlaced JJ cord-015369-72cjogxz 3095 10 left left JJ cord-015369-72cjogxz 3095 11 and and CC cord-015369-72cjogxz 3095 12 right right JJ cord-015369-72cjogxz 3095 13 ureter ureter NN cord-015369-72cjogxz 3095 14 had have VBD cord-015369-72cjogxz 3095 15 not not RB cord-015369-72cjogxz 3095 16 been be VBN cord-015369-72cjogxz 3095 17 recognized recognize VBN cord-015369-72cjogxz 3095 18 . . . cord-015369-72cjogxz 3096 1 Repair repair NN cord-015369-72cjogxz 3096 2 of of IN cord-015369-72cjogxz 3096 3 the the DT cord-015369-72cjogxz 3096 4 damaged damage VBN cord-015369-72cjogxz 3096 5 ureter ureter NN cord-015369-72cjogxz 3096 6 had have VBD cord-015369-72cjogxz 3096 7 failed fail VBN cord-015369-72cjogxz 3096 8 and and CC cord-015369-72cjogxz 3096 9 the the DT cord-015369-72cjogxz 3096 10 left left JJ cord-015369-72cjogxz 3096 11 kidney kidney NN cord-015369-72cjogxz 3096 12 had have VBD cord-015369-72cjogxz 3096 13 to to TO cord-015369-72cjogxz 3096 14 be be VB cord-015369-72cjogxz 3096 15 drained drain VBN cord-015369-72cjogxz 3096 16 by by IN cord-015369-72cjogxz 3096 17 a a DT cord-015369-72cjogxz 3096 18 J J NNP cord-015369-72cjogxz 3096 19 - - HYPH cord-015369-72cjogxz 3096 20 stent stent NN cord-015369-72cjogxz 3096 21 through through IN cord-015369-72cjogxz 3096 22 the the DT cord-015369-72cjogxz 3096 23 retroperitoneal retroperitoneal JJ cord-015369-72cjogxz 3096 24 space space NN cord-015369-72cjogxz 3096 25 into into IN cord-015369-72cjogxz 3096 26 the the DT cord-015369-72cjogxz 3096 27 bladder bladder NN cord-015369-72cjogxz 3096 28 . . . cord-015369-72cjogxz 3097 1 The the DT cord-015369-72cjogxz 3097 2 child child NN cord-015369-72cjogxz 3097 3 was be VBD cord-015369-72cjogxz 3097 4 transferred transfer VBN cord-015369-72cjogxz 3097 5 to to IN cord-015369-72cjogxz 3097 6 our -PRON- PRP$ cord-015369-72cjogxz 3097 7 institution institution NN cord-015369-72cjogxz 3097 8 at at IN cord-015369-72cjogxz 3097 9 6 6 CD cord-015369-72cjogxz 3097 10 months month NNS cord-015369-72cjogxz 3097 11 . . . cord-015369-72cjogxz 3098 1 Results result NNS cord-015369-72cjogxz 3098 2 . . . cord-015369-72cjogxz 3099 1 We -PRON- PRP cord-015369-72cjogxz 3099 2 interposed interpose VBD cord-015369-72cjogxz 3099 3 the the DT cord-015369-72cjogxz 3099 4 appendix appendix NN cord-015369-72cjogxz 3099 5 from from IN cord-015369-72cjogxz 3099 6 the the DT cord-015369-72cjogxz 3099 7 left left JJ cord-015369-72cjogxz 3099 8 renal renal JJ cord-015369-72cjogxz 3099 9 pelvis pelvi NNS cord-015369-72cjogxz 3099 10 to to IN cord-015369-72cjogxz 3099 11 the the DT cord-015369-72cjogxz 3099 12 bladder bladder NN cord-015369-72cjogxz 3099 13 . . . cord-015369-72cjogxz 3100 1 A a DT cord-015369-72cjogxz 3100 2 double double JJ cord-015369-72cjogxz 3100 3 J J NNP cord-015369-72cjogxz 3100 4 stent stent NN cord-015369-72cjogxz 3100 5 was be VBD cord-015369-72cjogxz 3100 6 inserted insert VBN cord-015369-72cjogxz 3100 7 for for IN cord-015369-72cjogxz 3100 8 four four CD cord-015369-72cjogxz 3100 9 weeks week NNS cord-015369-72cjogxz 3100 10 . . . cord-015369-72cjogxz 3101 1 Two two CD cord-015369-72cjogxz 3101 2 years year NNS cord-015369-72cjogxz 3101 3 afterwards afterwards RB cord-015369-72cjogxz 3101 4 this this DT cord-015369-72cjogxz 3101 5 child child NN cord-015369-72cjogxz 3101 6 is be VBZ cord-015369-72cjogxz 3101 7 thriving thrive VBG cord-015369-72cjogxz 3101 8 normally normally RB cord-015369-72cjogxz 3101 9 without without IN cord-015369-72cjogxz 3101 10 urinary urinary JJ cord-015369-72cjogxz 3101 11 tract tract JJ cord-015369-72cjogxz 3101 12 infections infection NNS cord-015369-72cjogxz 3101 13 and and CC cord-015369-72cjogxz 3101 14 normal normal JJ cord-015369-72cjogxz 3101 15 renal renal JJ cord-015369-72cjogxz 3101 16 function function NN cord-015369-72cjogxz 3101 17 . . . cord-015369-72cjogxz 3102 1 Discussion discussion NN cord-015369-72cjogxz 3102 2 . . . cord-015369-72cjogxz 3103 1 Ureteral ureteral JJ cord-015369-72cjogxz 3103 2 trauma trauma NN cord-015369-72cjogxz 3103 3 if if IN cord-015369-72cjogxz 3103 4 not not RB cord-015369-72cjogxz 3103 5 timely timely RB cord-015369-72cjogxz 3103 6 recognized recognize VBN cord-015369-72cjogxz 3103 7 can can MD cord-015369-72cjogxz 3103 8 lead lead VB cord-015369-72cjogxz 3103 9 to to IN cord-015369-72cjogxz 3103 10 urosepsis urosepsis NN cord-015369-72cjogxz 3103 11 and and CC cord-015369-72cjogxz 3103 12 renal renal JJ cord-015369-72cjogxz 3103 13 failure failure NN cord-015369-72cjogxz 3103 14 . . . cord-015369-72cjogxz 3104 1 Several several JJ cord-015369-72cjogxz 3104 2 techniques technique NNS cord-015369-72cjogxz 3104 3 have have VBP cord-015369-72cjogxz 3104 4 been be VBN cord-015369-72cjogxz 3104 5 described describe VBN cord-015369-72cjogxz 3104 6 for for IN cord-015369-72cjogxz 3104 7 the the DT cord-015369-72cjogxz 3104 8 replacement replacement NN cord-015369-72cjogxz 3104 9 of of IN cord-015369-72cjogxz 3104 10 long long JJ cord-015369-72cjogxz 3104 11 ureteral ureteral JJ cord-015369-72cjogxz 3104 12 segments segment NNS cord-015369-72cjogxz 3104 13 : : : cord-015369-72cjogxz 3104 14 the the DT cord-015369-72cjogxz 3104 15 use use NN cord-015369-72cjogxz 3104 16 of of IN cord-015369-72cjogxz 3104 17 urinary urinary JJ cord-015369-72cjogxz 3104 18 tract tract NN cord-015369-72cjogxz 3104 19 tissue tissue NN cord-015369-72cjogxz 3104 20 , , , cord-015369-72cjogxz 3104 21 the the DT cord-015369-72cjogxz 3104 22 Psoas Psoas NNP cord-015369-72cjogxz 3104 23 - - HYPH cord-015369-72cjogxz 3104 24 hitch hitch NN cord-015369-72cjogxz 3104 25 technique technique NN cord-015369-72cjogxz 3104 26 , , , cord-015369-72cjogxz 3104 27 pedicled pedicled JJ cord-015369-72cjogxz 3104 28 intestinal intestinal JJ cord-015369-72cjogxz 3104 29 segments segment NNS cord-015369-72cjogxz 3104 30 and and CC cord-015369-72cjogxz 3104 31 the the DT cord-015369-72cjogxz 3104 32 Yang Yang NNP cord-015369-72cjogxz 3104 33 - - HYPH cord-015369-72cjogxz 3104 34 Monti Monti NNP cord-015369-72cjogxz 3104 35 technique technique NN cord-015369-72cjogxz 3104 36 . . . cord-015369-72cjogxz 3105 1 The the DT cord-015369-72cjogxz 3105 2 appendix appendix NN cord-015369-72cjogxz 3105 3 is be VBZ cord-015369-72cjogxz 3105 4 similar similar JJ cord-015369-72cjogxz 3105 5 in in IN cord-015369-72cjogxz 3105 6 size size NN cord-015369-72cjogxz 3105 7 and and CC cord-015369-72cjogxz 3105 8 length length NN cord-015369-72cjogxz 3105 9 to to IN cord-015369-72cjogxz 3105 10 the the DT cord-015369-72cjogxz 3105 11 ureter ureter NN cord-015369-72cjogxz 3105 12 and and CC cord-015369-72cjogxz 3105 13 can can MD cord-015369-72cjogxz 3105 14 be be VB cord-015369-72cjogxz 3105 15 easily easily RB cord-015369-72cjogxz 3105 16 implantated implantate VBN cord-015369-72cjogxz 3105 17 with with IN cord-015369-72cjogxz 3105 18 an an DT cord-015369-72cjogxz 3105 19 antireflux antireflux NNP cord-015369-72cjogxz 3105 20 technique technique NN cord-015369-72cjogxz 3105 21 . . . cord-015369-72cjogxz 3106 1 Electrolyte electrolyte JJ cord-015369-72cjogxz 3106 2 absorption absorption NN cord-015369-72cjogxz 3106 3 and and CC cord-015369-72cjogxz 3106 4 mucous mucous JJ cord-015369-72cjogxz 3106 5 production production NN cord-015369-72cjogxz 3106 6 by by IN cord-015369-72cjogxz 3106 7 the the DT cord-015369-72cjogxz 3106 8 appendix appendix NN cord-015369-72cjogxz 3106 9 are be VBP cord-015369-72cjogxz 3106 10 negligible negligible JJ cord-015369-72cjogxz 3106 11 . . . cord-015369-72cjogxz 3107 1 Conclusions conclusion NNS cord-015369-72cjogxz 3107 2 . . . cord-015369-72cjogxz 3108 1 Only only RB cord-015369-72cjogxz 3108 2 a a DT cord-015369-72cjogxz 3108 3 few few JJ cord-015369-72cjogxz 3108 4 case case NN cord-015369-72cjogxz 3108 5 reports report NNS cord-015369-72cjogxz 3108 6 exist exist VBP cord-015369-72cjogxz 3108 7 in in IN cord-015369-72cjogxz 3108 8 which which WDT cord-015369-72cjogxz 3108 9 the the DT cord-015369-72cjogxz 3108 10 appendix appendix NN cord-015369-72cjogxz 3108 11 is be VBZ cord-015369-72cjogxz 3108 12 used use VBN cord-015369-72cjogxz 3108 13 as as IN cord-015369-72cjogxz 3108 14 a a DT cord-015369-72cjogxz 3108 15 replacement replacement NN cord-015369-72cjogxz 3108 16 of of IN cord-015369-72cjogxz 3108 17 the the DT cord-015369-72cjogxz 3108 18 left left JJ cord-015369-72cjogxz 3108 19 ureter ureter NN cord-015369-72cjogxz 3108 20 . . . cord-015369-72cjogxz 3109 1 This this DT cord-015369-72cjogxz 3109 2 case case NN cord-015369-72cjogxz 3109 3 adds add VBZ cord-015369-72cjogxz 3109 4 to to IN cord-015369-72cjogxz 3109 5 those those DT cord-015369-72cjogxz 3109 6 reports report NNS cord-015369-72cjogxz 3109 7 and and CC cord-015369-72cjogxz 3109 8 suggests suggest VBZ cord-015369-72cjogxz 3109 9 that that IN cord-015369-72cjogxz 3109 10 ureteral ureteral JJ cord-015369-72cjogxz 3109 11 reconstruction reconstruction NN cord-015369-72cjogxz 3109 12 using use VBG cord-015369-72cjogxz 3109 13 the the DT cord-015369-72cjogxz 3109 14 appendix appendix NNP cord-015369-72cjogxz 3109 15 vermiformis vermiformis NNP cord-015369-72cjogxz 3109 16 seems seem VBZ cord-015369-72cjogxz 3109 17 a a DT cord-015369-72cjogxz 3109 18 viable viable JJ cord-015369-72cjogxz 3109 19 technique technique NN cord-015369-72cjogxz 3109 20 even even RB cord-015369-72cjogxz 3109 21 when when WRB cord-015369-72cjogxz 3109 22 used use VBN cord-015369-72cjogxz 3109 23 as as IN cord-015369-72cjogxz 3109 24 a a DT cord-015369-72cjogxz 3109 25 replacement replacement NN cord-015369-72cjogxz 3109 26 of of IN cord-015369-72cjogxz 3109 27 the the DT cord-015369-72cjogxz 3109 28 left left JJ cord-015369-72cjogxz 3109 29 ureter ureter NN cord-015369-72cjogxz 3109 30 . . . cord-015369-72cjogxz 3110 1 Hypospadia Hypospadia NNP cord-015369-72cjogxz 3110 2 is be VBZ cord-015369-72cjogxz 3110 3 one one CD cord-015369-72cjogxz 3110 4 of of IN cord-015369-72cjogxz 3110 5 the the DT cord-015369-72cjogxz 3110 6 most most RBS cord-015369-72cjogxz 3110 7 common common JJ cord-015369-72cjogxz 3110 8 deformities deformity NNS cord-015369-72cjogxz 3110 9 of of IN cord-015369-72cjogxz 3110 10 the the DT cord-015369-72cjogxz 3110 11 uro uro JJ cord-015369-72cjogxz 3110 12 - - HYPH cord-015369-72cjogxz 3110 13 genital genital JJ cord-015369-72cjogxz 3110 14 system system NN cord-015369-72cjogxz 3110 15 . . . cord-015369-72cjogxz 3111 1 A a DT cord-015369-72cjogxz 3111 2 great great JJ cord-015369-72cjogxz 3111 3 diversity diversity NN cord-015369-72cjogxz 3111 4 of of IN cord-015369-72cjogxz 3111 5 procedures procedure NNS cord-015369-72cjogxz 3111 6 for for IN cord-015369-72cjogxz 3111 7 correction correction NN cord-015369-72cjogxz 3111 8 of of IN cord-015369-72cjogxz 3111 9 hypospadias hypospadia NNS cord-015369-72cjogxz 3111 10 is be VBZ cord-015369-72cjogxz 3111 11 suggested suggest VBN cord-015369-72cjogxz 3111 12 . . . cord-015369-72cjogxz 3112 1 At at IN cord-015369-72cjogxz 3112 2 our -PRON- PRP$ cord-015369-72cjogxz 3112 3 department department NN cord-015369-72cjogxz 3112 4 we -PRON- PRP cord-015369-72cjogxz 3112 5 use use VBP cord-015369-72cjogxz 3112 6 for for IN cord-015369-72cjogxz 3112 7 correction correction NN cord-015369-72cjogxz 3112 8 of of IN cord-015369-72cjogxz 3112 9 the the DT cord-015369-72cjogxz 3112 10 so so RB cord-015369-72cjogxz 3112 11 called call VBN cord-015369-72cjogxz 3112 12 ' ' '' cord-015369-72cjogxz 3112 13 ' ' `` cord-015369-72cjogxz 3112 14 distal distal JJ cord-015369-72cjogxz 3112 15 ' ' '' cord-015369-72cjogxz 3112 16 ' ' '' cord-015369-72cjogxz 3112 17 hypospadia hypospadia NNP cord-015369-72cjogxz 3112 18 mainly mainly RB cord-015369-72cjogxz 3112 19 one one CD cord-015369-72cjogxz 3112 20 method method NN cord-015369-72cjogxz 3112 21 : : : cord-015369-72cjogxz 3113 1 the the DT cord-015369-72cjogxz 3113 2 Y Y NNP cord-015369-72cjogxz 3113 3 - - HYPH cord-015369-72cjogxz 3113 4 V V NNP cord-015369-72cjogxz 3113 5 glanuloplasty glanuloplasty NN cord-015369-72cjogxz 3113 6 modified modify VBD cord-015369-72cjogxz 3113 7 Mathieu Mathieu NNP cord-015369-72cjogxz 3113 8 technique technique NN cord-015369-72cjogxz 3113 9 after after IN cord-015369-72cjogxz 3113 10 Hadidi Hadidi NNP cord-015369-72cjogxz 3113 11 . . . cord-015369-72cjogxz 3114 1 We -PRON- PRP cord-015369-72cjogxz 3114 2 investigated investigate VBD cord-015369-72cjogxz 3114 3 the the DT cord-015369-72cjogxz 3114 4 outcome outcome NN cord-015369-72cjogxz 3114 5 of of IN cord-015369-72cjogxz 3114 6 84 84 CD cord-015369-72cjogxz 3114 7 patients patient NNS cord-015369-72cjogxz 3114 8 with with IN cord-015369-72cjogxz 3114 9 distal distal JJ cord-015369-72cjogxz 3114 10 penile penile JJ cord-015369-72cjogxz 3114 11 hypospadia hypospadia NNS cord-015369-72cjogxz 3114 12 regarding regard VBG cord-015369-72cjogxz 3114 13 to to IN cord-015369-72cjogxz 3114 14 complications complication NNS cord-015369-72cjogxz 3114 15 , , , cord-015369-72cjogxz 3114 16 voiding void VBG cord-015369-72cjogxz 3114 17 function function NN cord-015369-72cjogxz 3114 18 and and CC cord-015369-72cjogxz 3114 19 cosmetic cosmetic JJ cord-015369-72cjogxz 3114 20 satisfaction satisfaction NN cord-015369-72cjogxz 3114 21 . . . cord-015369-72cjogxz 3115 1 The the DT cord-015369-72cjogxz 3115 2 mean mean JJ cord-015369-72cjogxz 3115 3 age age NN cord-015369-72cjogxz 3115 4 is be VBZ cord-015369-72cjogxz 3115 5 located locate VBN cord-015369-72cjogxz 3115 6 in in IN cord-015369-72cjogxz 3115 7 between between IN cord-015369-72cjogxz 3115 8 the the DT cord-015369-72cjogxz 3115 9 international international JJ cord-015369-72cjogxz 3115 10 recommended recommend VBN cord-015369-72cjogxz 3115 11 correction correction NN cord-015369-72cjogxz 3115 12 time time NN cord-015369-72cjogxz 3115 13 of of IN cord-015369-72cjogxz 3115 14 12 12 CD cord-015369-72cjogxz 3115 15 - - SYM cord-015369-72cjogxz 3115 16 18 18 CD cord-015369-72cjogxz 3115 17 month month NN cord-015369-72cjogxz 3115 18 . . . cord-015369-72cjogxz 3116 1 The the DT cord-015369-72cjogxz 3116 2 mean mean JJ cord-015369-72cjogxz 3116 3 observation observation NN cord-015369-72cjogxz 3116 4 time time NN cord-015369-72cjogxz 3116 5 is be VBZ cord-015369-72cjogxz 3116 6 35 35 CD cord-015369-72cjogxz 3116 7 months month NNS cord-015369-72cjogxz 3116 8 . . . cord-015369-72cjogxz 3117 1 Beside beside IN cord-015369-72cjogxz 3117 2 a a DT cord-015369-72cjogxz 3117 3 good good JJ cord-015369-72cjogxz 3117 4 cosmetic cosmetic JJ cord-015369-72cjogxz 3117 5 appearance appearance NN cord-015369-72cjogxz 3117 6 with with IN cord-015369-72cjogxz 3117 7 an an DT cord-015369-72cjogxz 3117 8 erectly erectly NN cord-015369-72cjogxz 3117 9 shape shape NN cord-015369-72cjogxz 3117 10 and and CC cord-015369-72cjogxz 3117 11 a a DT cord-015369-72cjogxz 3117 12 wide wide JJ cord-015369-72cjogxz 3117 13 meatus meatus NN cord-015369-72cjogxz 3117 14 , , , cord-015369-72cjogxz 3117 15 we -PRON- PRP cord-015369-72cjogxz 3117 16 found find VBD cord-015369-72cjogxz 3117 17 an an DT cord-015369-72cjogxz 3117 18 adequate adequate JJ cord-015369-72cjogxz 3117 19 voiding voiding NN cord-015369-72cjogxz 3117 20 function function NN cord-015369-72cjogxz 3117 21 . . . cord-015369-72cjogxz 3118 1 Fistulas Fistulas NNP cord-015369-72cjogxz 3118 2 occurred occur VBD cord-015369-72cjogxz 3118 3 after after IN cord-015369-72cjogxz 3118 4 failure failure NN cord-015369-72cjogxz 3118 5 of of IN cord-015369-72cjogxz 3118 6 wound wound NN cord-015369-72cjogxz 3118 7 - - HYPH cord-015369-72cjogxz 3118 8 healing healing NN cord-015369-72cjogxz 3118 9 in in IN cord-015369-72cjogxz 3118 10 two two CD cord-015369-72cjogxz 3118 11 cases case NNS cord-015369-72cjogxz 3118 12 . . . cord-015369-72cjogxz 3119 1 The the DT cord-015369-72cjogxz 3119 2 use use NN cord-015369-72cjogxz 3119 3 of of IN cord-015369-72cjogxz 3119 4 an an DT cord-015369-72cjogxz 3119 5 additional additional JJ cord-015369-72cjogxz 3119 6 layer layer NN cord-015369-72cjogxz 3119 7 of of IN cord-015369-72cjogxz 3119 8 connective connective JJ cord-015369-72cjogxz 3119 9 tissue tissue NN cord-015369-72cjogxz 3119 10 between between IN cord-015369-72cjogxz 3119 11 neo neo NNP cord-015369-72cjogxz 3119 12 - - NN cord-015369-72cjogxz 3119 13 urethra urethra NN cord-015369-72cjogxz 3119 14 and and CC cord-015369-72cjogxz 3119 15 skin skin NN cord-015369-72cjogxz 3119 16 seemed seem VBD cord-015369-72cjogxz 3119 17 to to TO cord-015369-72cjogxz 3119 18 be be VB cord-015369-72cjogxz 3119 19 beneficial beneficial JJ cord-015369-72cjogxz 3119 20 against against IN cord-015369-72cjogxz 3119 21 occurrence occurrence NN cord-015369-72cjogxz 3119 22 of of IN cord-015369-72cjogxz 3119 23 fistulas fistula NNS cord-015369-72cjogxz 3119 24 . . . cord-015369-72cjogxz 3120 1 In in IN cord-015369-72cjogxz 3120 2 contrast contrast NN cord-015369-72cjogxz 3120 3 to to IN cord-015369-72cjogxz 3120 4 other other JJ cord-015369-72cjogxz 3120 5 urethroplasties urethroplastie NNS cord-015369-72cjogxz 3120 6 , , , cord-015369-72cjogxz 3120 7 we -PRON- PRP cord-015369-72cjogxz 3120 8 do do VBP cord-015369-72cjogxz 3120 9 not not RB cord-015369-72cjogxz 3120 10 use use VB cord-015369-72cjogxz 3120 11 any any DT cord-015369-72cjogxz 3120 12 stent stent NN cord-015369-72cjogxz 3120 13 or or CC cord-015369-72cjogxz 3120 14 catheter catheter NN cord-015369-72cjogxz 3120 15 in in IN cord-015369-72cjogxz 3120 16 the the DT cord-015369-72cjogxz 3120 17 Y Y NNP cord-015369-72cjogxz 3120 18 - - HYPH cord-015369-72cjogxz 3120 19 V V NNP cord-015369-72cjogxz 3120 20 glanuloplasty glanuloplasty NN cord-015369-72cjogxz 3120 21 modified modify VBD cord-015369-72cjogxz 3120 22 Mathieu Mathieu NNP cord-015369-72cjogxz 3120 23 technique technique NN cord-015369-72cjogxz 3120 24 and and CC cord-015369-72cjogxz 3120 25 the the DT cord-015369-72cjogxz 3120 26 patients patient NNS cord-015369-72cjogxz 3120 27 void void VBP cord-015369-72cjogxz 3120 28 immediately immediately RB cord-015369-72cjogxz 3120 29 after after IN cord-015369-72cjogxz 3120 30 the the DT cord-015369-72cjogxz 3120 31 surgical surgical JJ cord-015369-72cjogxz 3120 32 procedure procedure NN cord-015369-72cjogxz 3120 33 through through IN cord-015369-72cjogxz 3120 34 the the DT cord-015369-72cjogxz 3120 35 neo neo NNP cord-015369-72cjogxz 3120 36 - - HYPH cord-015369-72cjogxz 3120 37 urethra urethra NNP cord-015369-72cjogxz 3120 38 . . . cord-015369-72cjogxz 3121 1 The the DT cord-015369-72cjogxz 3121 2 crucial crucial JJ cord-015369-72cjogxz 3121 3 element element NN cord-015369-72cjogxz 3121 4 is be VBZ cord-015369-72cjogxz 3121 5 , , , cord-015369-72cjogxz 3121 6 in in IN cord-015369-72cjogxz 3121 7 our -PRON- PRP$ cord-015369-72cjogxz 3121 8 opinion opinion NN cord-015369-72cjogxz 3121 9 , , , cord-015369-72cjogxz 3121 10 an an DT cord-015369-72cjogxz 3121 11 adequate adequate JJ cord-015369-72cjogxz 3121 12 pain pain NN cord-015369-72cjogxz 3121 13 relief relief NN cord-015369-72cjogxz 3121 14 during during IN cord-015369-72cjogxz 3121 15 the the DT cord-015369-72cjogxz 3121 16 first first JJ cord-015369-72cjogxz 3121 17 two two CD cord-015369-72cjogxz 3121 18 days day NNS cord-015369-72cjogxz 3121 19 so so IN cord-015369-72cjogxz 3121 20 that that IN cord-015369-72cjogxz 3121 21 the the DT cord-015369-72cjogxz 3121 22 patient patient NN cord-015369-72cjogxz 3121 23 wo will MD cord-015369-72cjogxz 3121 24 n't not RB cord-015369-72cjogxz 3121 25 get get VB cord-015369-72cjogxz 3121 26 a a DT cord-015369-72cjogxz 3121 27 voiding voiding NN cord-015369-72cjogxz 3121 28 problem problem NN cord-015369-72cjogxz 3121 29 . . . cord-015369-72cjogxz 3122 1 The the DT cord-015369-72cjogxz 3122 2 mean mean JJ cord-015369-72cjogxz 3122 3 hospital hospital NN cord-015369-72cjogxz 3122 4 stay stay NN cord-015369-72cjogxz 3122 5 was be VBD cord-015369-72cjogxz 3122 6 3 3 CD cord-015369-72cjogxz 3122 7 - - SYM cord-015369-72cjogxz 3122 8 5 5 CD cord-015369-72cjogxz 3122 9 days day NNS cord-015369-72cjogxz 3122 10 . . . cord-015369-72cjogxz 3123 1 All all RB cord-015369-72cjogxz 3123 2 over over RB cord-015369-72cjogxz 3123 3 , , , cord-015369-72cjogxz 3123 4 we -PRON- PRP cord-015369-72cjogxz 3123 5 think think VBP cord-015369-72cjogxz 3123 6 that that IN cord-015369-72cjogxz 3123 7 the the DT cord-015369-72cjogxz 3123 8 patients patient NNS cord-015369-72cjogxz 3123 9 benefit benefit VBP cord-015369-72cjogxz 3123 10 from from IN cord-015369-72cjogxz 3123 11 the the DT cord-015369-72cjogxz 3123 12 Y Y NNP cord-015369-72cjogxz 3123 13 - - HYPH cord-015369-72cjogxz 3123 14 V V NNP cord-015369-72cjogxz 3123 15 glanuloplasty glanuloplasty NN cord-015369-72cjogxz 3123 16 modified modify VBD cord-015369-72cjogxz 3123 17 Mathieu Mathieu NNP cord-015369-72cjogxz 3123 18 technique technique NN cord-015369-72cjogxz 3123 19 as as IN cord-015369-72cjogxz 3123 20 for for IN cord-015369-72cjogxz 3123 21 this this DT cord-015369-72cjogxz 3123 22 method method NN cord-015369-72cjogxz 3124 1 we -PRON- PRP cord-015369-72cjogxz 3124 2 do do VBP cord-015369-72cjogxz 3124 3 not not RB cord-015369-72cjogxz 3124 4 use use VB cord-015369-72cjogxz 3124 5 urethral urethral JJ cord-015369-72cjogxz 3124 6 stenting stenting NN cord-015369-72cjogxz 3124 7 nor nor CC cord-015369-72cjogxz 3124 8 any any DT cord-015369-72cjogxz 3124 9 kind kind NN cord-015369-72cjogxz 3124 10 of of IN cord-015369-72cjogxz 3124 11 dressing dressing NN cord-015369-72cjogxz 3124 12 . . . cord-015369-72cjogxz 3125 1 Background background NN cord-015369-72cjogxz 3125 2 . . . cord-015369-72cjogxz 3126 1 During during IN cord-015369-72cjogxz 3126 2 laparoscopic laparoscopic JJ cord-015369-72cjogxz 3126 3 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 3126 4 ( ( -LRB- cord-015369-72cjogxz 3126 5 LC LC NNP cord-015369-72cjogxz 3126 6 ) ) -RRB- cord-015369-72cjogxz 3126 7 for for IN cord-015369-72cjogxz 3126 8 symptomatic symptomatic JJ cord-015369-72cjogxz 3126 9 gallstone gallstone NN cord-015369-72cjogxz 3126 10 disease disease NN cord-015369-72cjogxz 3126 11 injury injury NN cord-015369-72cjogxz 3126 12 of of IN cord-015369-72cjogxz 3126 13 the the DT cord-015369-72cjogxz 3126 14 gallbladder gallbladder NN cord-015369-72cjogxz 3126 15 with with IN cord-015369-72cjogxz 3126 16 spillage spillage NN cord-015369-72cjogxz 3126 17 of of IN cord-015369-72cjogxz 3126 18 stones stone NNS cord-015369-72cjogxz 3126 19 occurs occur VBZ cord-015369-72cjogxz 3126 20 frequently frequently RB cord-015369-72cjogxz 3126 21 . . . cord-015369-72cjogxz 3127 1 Subphrenic subphrenic JJ cord-015369-72cjogxz 3127 2 abscess abscess NN cord-015369-72cjogxz 3127 3 after after IN cord-015369-72cjogxz 3127 4 LC LC NNP cord-015369-72cjogxz 3127 5 is be VBZ cord-015369-72cjogxz 3127 6 a a DT cord-015369-72cjogxz 3127 7 rare rare JJ cord-015369-72cjogxz 3127 8 complication complication NN cord-015369-72cjogxz 3127 9 of of IN cord-015369-72cjogxz 3127 10 this this DT cord-015369-72cjogxz 3127 11 condition condition NN cord-015369-72cjogxz 3127 12 and and CC cord-015369-72cjogxz 3127 13 may may MD cord-015369-72cjogxz 3127 14 cause cause VB cord-015369-72cjogxz 3127 15 diagnostic diagnostic JJ cord-015369-72cjogxz 3127 16 dilemmas dilemma NNS cord-015369-72cjogxz 3127 17 and and CC cord-015369-72cjogxz 3127 18 delayed delay VBN cord-015369-72cjogxz 3127 19 treatment treatment NN cord-015369-72cjogxz 3127 20 . . . cord-015369-72cjogxz 3128 1 Methods method NNS cord-015369-72cjogxz 3128 2 . . . cord-015369-72cjogxz 3129 1 We -PRON- PRP cord-015369-72cjogxz 3129 2 present present VBP cord-015369-72cjogxz 3129 3 a a DT cord-015369-72cjogxz 3129 4 case case NN cord-015369-72cjogxz 3129 5 report report NN cord-015369-72cjogxz 3129 6 of of IN cord-015369-72cjogxz 3129 7 a a DT cord-015369-72cjogxz 3129 8 patient patient NN cord-015369-72cjogxz 3129 9 with with IN cord-015369-72cjogxz 3129 10 subprenic subprenic JJ cord-015369-72cjogxz 3129 11 abscess abscess NN cord-015369-72cjogxz 3129 12 formation formation NN cord-015369-72cjogxz 3129 13 due due IN cord-015369-72cjogxz 3129 14 to to IN cord-015369-72cjogxz 3129 15 a a DT cord-015369-72cjogxz 3129 16 lost lost JJ cord-015369-72cjogxz 3129 17 gallstone gallstone NN cord-015369-72cjogxz 3129 18 and and CC cord-015369-72cjogxz 3129 19 a a DT cord-015369-72cjogxz 3129 20 review review NN cord-015369-72cjogxz 3129 21 of of IN cord-015369-72cjogxz 3129 22 the the DT cord-015369-72cjogxz 3129 23 current current JJ cord-015369-72cjogxz 3129 24 literature literature NN cord-015369-72cjogxz 3129 25 . . . cord-015369-72cjogxz 3130 1 Case case NN cord-015369-72cjogxz 3130 2 . . . cord-015369-72cjogxz 3131 1 After after IN cord-015369-72cjogxz 3131 2 a a DT cord-015369-72cjogxz 3131 3 stay stay NN cord-015369-72cjogxz 3131 4 in in IN cord-015369-72cjogxz 3131 5 India India NNP cord-015369-72cjogxz 3131 6 a a DT cord-015369-72cjogxz 3131 7 49 49 CD cord-015369-72cjogxz 3131 8 year year NN cord-015369-72cjogxz 3131 9 old old JJ cord-015369-72cjogxz 3131 10 female female JJ cord-015369-72cjogxz 3131 11 patient patient NN cord-015369-72cjogxz 3131 12 presented present VBN cord-015369-72cjogxz 3131 13 with with IN cord-015369-72cjogxz 3131 14 a a DT cord-015369-72cjogxz 3131 15 subprenic subprenic JJ cord-015369-72cjogxz 3131 16 abscess abscess NN cord-015369-72cjogxz 3131 17 formation formation NN cord-015369-72cjogxz 3131 18 mimicking mimic VBG cord-015369-72cjogxz 3131 19 a a DT cord-015369-72cjogxz 3131 20 liver liver NN cord-015369-72cjogxz 3131 21 abscess abscess NN cord-015369-72cjogxz 3131 22 and and CC cord-015369-72cjogxz 3131 23 pleural pleural JJ cord-015369-72cjogxz 3131 24 effusion effusion NN cord-015369-72cjogxz 3131 25 . . . cord-015369-72cjogxz 3132 1 Her -PRON- PRP$ cord-015369-72cjogxz 3132 2 medical medical JJ cord-015369-72cjogxz 3132 3 history history NN cord-015369-72cjogxz 3132 4 implied imply VBD cord-015369-72cjogxz 3132 5 a a DT cord-015369-72cjogxz 3132 6 hysterectomy hysterectomy NN cord-015369-72cjogxz 3132 7 for for IN cord-015369-72cjogxz 3132 8 cervical cervical JJ cord-015369-72cjogxz 3132 9 cancer cancer NN cord-015369-72cjogxz 3132 10 and and CC cord-015369-72cjogxz 3132 11 a a DT cord-015369-72cjogxz 3132 12 LC LC NNP cord-015369-72cjogxz 3132 13 . . . cord-015369-72cjogxz 3133 1 The the DT cord-015369-72cjogxz 3133 2 diagnostic diagnostic JJ cord-015369-72cjogxz 3133 3 and and CC cord-015369-72cjogxz 3133 4 therapeutic therapeutic JJ cord-015369-72cjogxz 3133 5 management management NN cord-015369-72cjogxz 3133 6 is be VBZ cord-015369-72cjogxz 3133 7 exactly exactly RB cord-015369-72cjogxz 3133 8 processed process VBN cord-015369-72cjogxz 3133 9 . . . cord-015369-72cjogxz 3134 1 Results result NNS cord-015369-72cjogxz 3134 2 . . . cord-015369-72cjogxz 3135 1 Spillage spillage NN cord-015369-72cjogxz 3135 2 of of IN cord-015369-72cjogxz 3135 3 stones stone NNS cord-015369-72cjogxz 3135 4 at at IN cord-015369-72cjogxz 3135 5 LC LC NNP cord-015369-72cjogxz 3135 6 occurs occur VBZ cord-015369-72cjogxz 3135 7 in in IN cord-015369-72cjogxz 3135 8 0,1 0,1 CD cord-015369-72cjogxz 3135 9 - - SYM cord-015369-72cjogxz 3135 10 20 20 CD cord-015369-72cjogxz 3135 11 % % NN cord-015369-72cjogxz 3135 12 . . . cord-015369-72cjogxz 3136 1 In in IN cord-015369-72cjogxz 3136 2 a a DT cord-015369-72cjogxz 3136 3 systematic systematic JJ cord-015369-72cjogxz 3136 4 review review NN cord-015369-72cjogxz 3136 5 the the DT cord-015369-72cjogxz 3136 6 complication complication NN cord-015369-72cjogxz 3136 7 rate rate NN cord-015369-72cjogxz 3136 8 of of IN cord-015369-72cjogxz 3136 9 lost lose VBN cord-015369-72cjogxz 3136 10 gallstones gallstone NNS cord-015369-72cjogxz 3136 11 is be VBZ cord-015369-72cjogxz 3136 12 stated state VBN cord-015369-72cjogxz 3136 13 to to TO cord-015369-72cjogxz 3136 14 be be VB cord-015369-72cjogxz 3136 15 3 3 CD cord-015369-72cjogxz 3136 16 - - SYM cord-015369-72cjogxz 3136 17 12 12 CD cord-015369-72cjogxz 3136 18 % % NN cord-015369-72cjogxz 3136 19 . . . cord-015369-72cjogxz 3137 1 A a DT cord-015369-72cjogxz 3137 2 large large JJ cord-015369-72cjogxz 3137 3 variety variety NN cord-015369-72cjogxz 3137 4 of of IN cord-015369-72cjogxz 3137 5 complications complication NNS cord-015369-72cjogxz 3137 6 , , , cord-015369-72cjogxz 3137 7 some some DT cord-015369-72cjogxz 3137 8 with with IN cord-015369-72cjogxz 3137 9 serious serious JJ cord-015369-72cjogxz 3137 10 morbidity morbidity NN cord-015369-72cjogxz 3137 11 , , , cord-015369-72cjogxz 3137 12 has have VBZ cord-015369-72cjogxz 3137 13 been be VBN cord-015369-72cjogxz 3137 14 described describe VBN cord-015369-72cjogxz 3137 15 . . . cord-015369-72cjogxz 3138 1 Only only RB cord-015369-72cjogxz 3138 2 18 18 CD cord-015369-72cjogxz 3138 3 cases case NNS cord-015369-72cjogxz 3138 4 of of IN cord-015369-72cjogxz 3138 5 subphrenic subphrenic JJ cord-015369-72cjogxz 3138 6 abscess abscess NN cord-015369-72cjogxz 3138 7 have have VBP cord-015369-72cjogxz 3138 8 been be VBN cord-015369-72cjogxz 3138 9 reported report VBN cord-015369-72cjogxz 3138 10 previously previously RB cord-015369-72cjogxz 3138 11 . . . cord-015369-72cjogxz 3139 1 Conclusions conclusion NNS cord-015369-72cjogxz 3139 2 . . . cord-015369-72cjogxz 3140 1 Every every DT cord-015369-72cjogxz 3140 2 effort effort NN cord-015369-72cjogxz 3140 3 should should MD cord-015369-72cjogxz 3140 4 be be VB cord-015369-72cjogxz 3140 5 made make VBN cord-015369-72cjogxz 3140 6 to to TO cord-015369-72cjogxz 3140 7 extract extract VB cord-015369-72cjogxz 3140 8 lost lose VBN cord-015369-72cjogxz 3140 9 gallstones gallstone NNS cord-015369-72cjogxz 3140 10 at at IN cord-015369-72cjogxz 3140 11 LC LC NNP cord-015369-72cjogxz 3140 12 laparoscopically laparoscopically RB cord-015369-72cjogxz 3140 13 . . . cord-015369-72cjogxz 3141 1 No no DT cord-015369-72cjogxz 3141 2 conversion conversion NN cord-015369-72cjogxz 3141 3 to to IN cord-015369-72cjogxz 3141 4 an an DT cord-015369-72cjogxz 3141 5 open open JJ cord-015369-72cjogxz 3141 6 procedure procedure NN cord-015369-72cjogxz 3141 7 is be VBZ cord-015369-72cjogxz 3141 8 necessary necessary JJ cord-015369-72cjogxz 3141 9 because because IN cord-015369-72cjogxz 3141 10 of of IN cord-015369-72cjogxz 3141 11 a a DT cord-015369-72cjogxz 3141 12 low low JJ cord-015369-72cjogxz 3141 13 incidence incidence NN cord-015369-72cjogxz 3141 14 of of IN cord-015369-72cjogxz 3141 15 complication complication NN cord-015369-72cjogxz 3141 16 rate rate NN cord-015369-72cjogxz 3141 17 . . . cord-015369-72cjogxz 3142 1 Composition composition NN cord-015369-72cjogxz 3142 2 of of IN cord-015369-72cjogxz 3142 3 gallstones gallstone NNS cord-015369-72cjogxz 3142 4 and and CC cord-015369-72cjogxz 3142 5 bacteriological bacteriological JJ cord-015369-72cjogxz 3142 6 culture culture NN cord-015369-72cjogxz 3142 7 of of IN cord-015369-72cjogxz 3142 8 bile bile NN cord-015369-72cjogxz 3142 9 is be VBZ cord-015369-72cjogxz 3142 10 beneficial beneficial JJ cord-015369-72cjogxz 3142 11 for for IN cord-015369-72cjogxz 3142 12 prognosis prognosis NN cord-015369-72cjogxz 3142 13 of of IN cord-015369-72cjogxz 3142 14 possible possible JJ cord-015369-72cjogxz 3142 15 complications complication NNS cord-015369-72cjogxz 3142 16 and and CC cord-015369-72cjogxz 3142 17 their -PRON- PRP$ cord-015369-72cjogxz 3142 18 treatment treatment NN cord-015369-72cjogxz 3142 19 . . . cord-015369-72cjogxz 3143 1 Lost lose VBN cord-015369-72cjogxz 3143 2 stones stone NNS cord-015369-72cjogxz 3143 3 should should MD cord-015369-72cjogxz 3143 4 be be VB cord-015369-72cjogxz 3143 5 noticed notice VBN cord-015369-72cjogxz 3143 6 in in IN cord-015369-72cjogxz 3143 7 the the DT cord-015369-72cjogxz 3143 8 operation operation NN cord-015369-72cjogxz 3143 9 report report NN cord-015369-72cjogxz 3143 10 and and CC cord-015369-72cjogxz 3143 11 the the DT cord-015369-72cjogxz 3143 12 patient patient NN cord-015369-72cjogxz 3143 13 should should MD cord-015369-72cjogxz 3143 14 be be VB cord-015369-72cjogxz 3143 15 informed inform VBN cord-015369-72cjogxz 3143 16 that that IN cord-015369-72cjogxz 3143 17 in in IN cord-015369-72cjogxz 3143 18 the the DT cord-015369-72cjogxz 3143 19 case case NN cord-015369-72cjogxz 3143 20 of of IN cord-015369-72cjogxz 3143 21 complications complication NNS cord-015369-72cjogxz 3143 22 the the DT cord-015369-72cjogxz 3143 23 diagnostic diagnostic JJ cord-015369-72cjogxz 3143 24 and and CC cord-015369-72cjogxz 3143 25 therapeutic therapeutic JJ cord-015369-72cjogxz 3143 26 way way NN cord-015369-72cjogxz 3143 27 can can MD cord-015369-72cjogxz 3143 28 be be VB cord-015369-72cjogxz 3143 29 easier easy JJR cord-015369-72cjogxz 3143 30 and and CC cord-015369-72cjogxz 3143 31 performed perform VBN cord-015369-72cjogxz 3143 32 in in IN cord-015369-72cjogxz 3143 33 a a DT cord-015369-72cjogxz 3143 34 shorter short JJR cord-015369-72cjogxz 3143 35 time time NN cord-015369-72cjogxz 3143 36 . . . cord-015369-72cjogxz 3144 1 Conservative conservative JJ cord-015369-72cjogxz 3144 2 treatment treatment NN cord-015369-72cjogxz 3144 3 has have VBZ cord-015369-72cjogxz 3144 4 a a DT cord-015369-72cjogxz 3144 5 high high JJ cord-015369-72cjogxz 3144 6 failure failure NN cord-015369-72cjogxz 3144 7 rate rate NN cord-015369-72cjogxz 3144 8 . . . cord-015369-72cjogxz 3145 1 Outcome outcome NN cord-015369-72cjogxz 3145 2 of of IN cord-015369-72cjogxz 3145 3 laparoscopic laparoscopic JJ cord-015369-72cjogxz 3145 4 incisional incisional NNP cord-015369-72cjogxz 3145 5 hernia hernia NN cord-015369-72cjogxz 3145 6 repair repair NN cord-015369-72cjogxz 3145 7 in in IN cord-015369-72cjogxz 3145 8 immunocompromised immunocompromised JJ cord-015369-72cjogxz 3145 9 patients patient NNS cord-015369-72cjogxz 3145 10 following follow VBG cord-015369-72cjogxz 3145 11 liver liver NN cord-015369-72cjogxz 3145 12 transplantation transplantation NN cord-015369-72cjogxz 3145 13 Background Background NNP cord-015369-72cjogxz 3145 14 . . . cord-015369-72cjogxz 3146 1 Incisional Incisional NNP cord-015369-72cjogxz 3146 2 hernias hernia NNS cord-015369-72cjogxz 3146 3 occur occur VBP cord-015369-72cjogxz 3146 4 in in IN cord-015369-72cjogxz 3146 5 up up IN cord-015369-72cjogxz 3146 6 to to TO cord-015369-72cjogxz 3146 7 12 12 CD cord-015369-72cjogxz 3146 8 % % NN cord-015369-72cjogxz 3146 9 of of IN cord-015369-72cjogxz 3146 10 patients patient NNS cord-015369-72cjogxz 3146 11 following follow VBG cord-015369-72cjogxz 3146 12 liver liver NN cord-015369-72cjogxz 3146 13 transplantation transplantation NN cord-015369-72cjogxz 3146 14 ( ( -LRB- cord-015369-72cjogxz 3146 15 LTX LTX NNP cord-015369-72cjogxz 3146 16 ) ) -RRB- cord-015369-72cjogxz 3146 17 . . . cord-015369-72cjogxz 3147 1 Laparoscopic Laparoscopic NNP cord-015369-72cjogxz 3147 2 incisional incisional JJ cord-015369-72cjogxz 3147 3 hernia hernia NN cord-015369-72cjogxz 3147 4 repair repair NN cord-015369-72cjogxz 3147 5 ( ( -LRB- cord-015369-72cjogxz 3147 6 LIHR LIHR NNP cord-015369-72cjogxz 3147 7 ) ) -RRB- cord-015369-72cjogxz 3147 8 is be VBZ cord-015369-72cjogxz 3147 9 well well RB cord-015369-72cjogxz 3147 10 established establish VBN cord-015369-72cjogxz 3147 11 in in IN cord-015369-72cjogxz 3147 12 immunocompetent immunocompetent JJ cord-015369-72cjogxz 3147 13 patients patient NNS cord-015369-72cjogxz 3147 14 , , , cord-015369-72cjogxz 3147 15 and and CC cord-015369-72cjogxz 3147 16 has have VBZ cord-015369-72cjogxz 3147 17 been be VBN cord-015369-72cjogxz 3147 18 increasingly increasingly RB cord-015369-72cjogxz 3147 19 used use VBN cord-015369-72cjogxz 3147 20 in in IN cord-015369-72cjogxz 3147 21 transplant transplant NN cord-015369-72cjogxz 3147 22 patients patient NNS cord-015369-72cjogxz 3147 23 . . . cord-015369-72cjogxz 3148 1 We -PRON- PRP cord-015369-72cjogxz 3148 2 report report VBP cord-015369-72cjogxz 3148 3 on on IN cord-015369-72cjogxz 3148 4 our -PRON- PRP$ cord-015369-72cjogxz 3148 5 experience experience NN cord-015369-72cjogxz 3148 6 with with IN cord-015369-72cjogxz 3148 7 LIHR LIHR NNP cord-015369-72cjogxz 3148 8 after after IN cord-015369-72cjogxz 3148 9 LTX LTX NNP cord-015369-72cjogxz 3148 10 . . . cord-015369-72cjogxz 3149 1 Methods method NNS cord-015369-72cjogxz 3149 2 . . . cord-015369-72cjogxz 3150 1 In in IN cord-015369-72cjogxz 3150 2 a a DT cord-015369-72cjogxz 3150 3 48-month 48-month JJ cord-015369-72cjogxz 3150 4 period period NN cord-015369-72cjogxz 3150 5 , , , cord-015369-72cjogxz 3150 6 all all DT cord-015369-72cjogxz 3150 7 patients patient NNS cord-015369-72cjogxz 3150 8 undergoing undergo VBG cord-015369-72cjogxz 3150 9 LIHR LIHR NNP cord-015369-72cjogxz 3150 10 after after IN cord-015369-72cjogxz 3150 11 LTX LTX NNP cord-015369-72cjogxz 3150 12 were be VBD cord-015369-72cjogxz 3150 13 included include VBN cord-015369-72cjogxz 3150 14 in in IN cord-015369-72cjogxz 3150 15 this this DT cord-015369-72cjogxz 3150 16 retrospective retrospective JJ cord-015369-72cjogxz 3150 17 study study NN cord-015369-72cjogxz 3150 18 . . . cord-015369-72cjogxz 3151 1 Results result NNS cord-015369-72cjogxz 3151 2 are be VBP cord-015369-72cjogxz 3151 3 reported report VBN cord-015369-72cjogxz 3151 4 as as IN cord-015369-72cjogxz 3151 5 mean mean JJ cord-015369-72cjogxz 3151 6 AE AE NNP cord-015369-72cjogxz 3151 7 SD SD NNP cord-015369-72cjogxz 3151 8 or or CC cord-015369-72cjogxz 3151 9 total total JJ cord-015369-72cjogxz 3151 10 number number NN cord-015369-72cjogxz 3151 11 ( ( -LRB- cord-015369-72cjogxz 3151 12 % % NN cord-015369-72cjogxz 3151 13 ) ) -RRB- cord-015369-72cjogxz 3151 14 . . . cord-015369-72cjogxz 3152 1 Results result NNS cord-015369-72cjogxz 3152 2 . . . cord-015369-72cjogxz 3153 1 Fifteen fifteen CD cord-015369-72cjogxz 3153 2 patients patient NNS cord-015369-72cjogxz 3153 3 ( ( -LRB- cord-015369-72cjogxz 3153 4 6.7 6.7 CD cord-015369-72cjogxz 3153 5 % % NN cord-015369-72cjogxz 3153 6 female female JJ cord-015369-72cjogxz 3153 7 ; ; : cord-015369-72cjogxz 3153 8 age age NN cord-015369-72cjogxz 3153 9 59.4 59.4 CD cord-015369-72cjogxz 3153 10 8.01 8.01 CD cord-015369-72cjogxz 3153 11 years year NNS cord-015369-72cjogxz 3153 12 ) ) -RRB- cord-015369-72cjogxz 3153 13 were be VBD cord-015369-72cjogxz 3153 14 included include VBN cord-015369-72cjogxz 3153 15 . . . cord-015369-72cjogxz 3154 1 Mean mean JJ cord-015369-72cjogxz 3154 2 time time NN cord-015369-72cjogxz 3154 3 from from IN cord-015369-72cjogxz 3154 4 LTX LTX NNP cord-015369-72cjogxz 3154 5 to to IN cord-015369-72cjogxz 3154 6 LIHR LIHR NNP cord-015369-72cjogxz 3154 7 was be VBD cord-015369-72cjogxz 3154 8 29.4 29.4 CD cord-015369-72cjogxz 3154 9 28.5 28.5 CD cord-015369-72cjogxz 3154 10 months month NNS cord-015369-72cjogxz 3154 11 . . . cord-015369-72cjogxz 3155 1 Hernia Hernia NNP cord-015369-72cjogxz 3155 2 location location NN cord-015369-72cjogxz 3155 3 was be VBD cord-015369-72cjogxz 3155 4 midline midline JJ cord-015369-72cjogxz 3155 5 in in IN cord-015369-72cjogxz 3155 6 9 9 CD cord-015369-72cjogxz 3155 7 ( ( -LRB- cord-015369-72cjogxz 3155 8 60.0 60.0 CD cord-015369-72cjogxz 3155 9 % % NN cord-015369-72cjogxz 3155 10 ) ) -RRB- cord-015369-72cjogxz 3155 11 , , , cord-015369-72cjogxz 3155 12 laterally laterally RB cord-015369-72cjogxz 3155 13 in in IN cord-015369-72cjogxz 3155 14 3 3 CD cord-015369-72cjogxz 3155 15 ( ( -LRB- cord-015369-72cjogxz 3155 16 20 20 CD cord-015369-72cjogxz 3155 17 % % NN cord-015369-72cjogxz 3155 18 ) ) -RRB- cord-015369-72cjogxz 3155 19 and and CC cord-015369-72cjogxz 3155 20 both both CC cord-015369-72cjogxz 3155 21 in in IN cord-015369-72cjogxz 3155 22 3 3 CD cord-015369-72cjogxz 3155 23 patients patient NNS cord-015369-72cjogxz 3155 24 ( ( -LRB- cord-015369-72cjogxz 3155 25 20 20 CD cord-015369-72cjogxz 3155 26 % % NN cord-015369-72cjogxz 3155 27 ) ) -RRB- cord-015369-72cjogxz 3155 28 . . . cord-015369-72cjogxz 3156 1 Immunosuppression Immunosuppression NNP cord-015369-72cjogxz 3156 2 was be VBD cord-015369-72cjogxz 3156 3 calcineurin calcineurin NN cord-015369-72cjogxz 3156 4 - - HYPH cord-015369-72cjogxz 3156 5 inhibitor inhibitor NN cord-015369-72cjogxz 3156 6 based base VBN cord-015369-72cjogxz 3156 7 ( ( -LRB- cord-015369-72cjogxz 3156 8 tacrolimus tacrolimus NNP cord-015369-72cjogxz 3156 9 40 40 CD cord-015369-72cjogxz 3156 10 % % NN cord-015369-72cjogxz 3156 11 / / SYM cord-015369-72cjogxz 3156 12 cyclosporine cyclosporine NN cord-015369-72cjogxz 3156 13 60 60 CD cord-015369-72cjogxz 3156 14 % % NN cord-015369-72cjogxz 3156 15 ) ) -RRB- cord-015369-72cjogxz 3156 16 with with IN cord-015369-72cjogxz 3156 17 a a DT cord-015369-72cjogxz 3156 18 tapered tapered JJ cord-015369-72cjogxz 3156 19 steroid steroid NN cord-015369-72cjogxz 3156 20 regimen regimen NN cord-015369-72cjogxz 3156 21 in in IN cord-015369-72cjogxz 3156 22 all all DT cord-015369-72cjogxz 3156 23 patients patient NNS cord-015369-72cjogxz 3156 24 . . . cord-015369-72cjogxz 3157 1 Hernia Hernia NNP cord-015369-72cjogxz 3157 2 repair repair NN cord-015369-72cjogxz 3157 3 was be VBD cord-015369-72cjogxz 3157 4 technically technically RB cord-015369-72cjogxz 3157 5 successful successful JJ cord-015369-72cjogxz 3157 6 in in IN cord-015369-72cjogxz 3157 7 all all DT cord-015369-72cjogxz 3157 8 cases case NNS cord-015369-72cjogxz 3157 9 using use VBG cord-015369-72cjogxz 3157 10 a a DT cord-015369-72cjogxz 3157 11 polyester polyester NN cord-015369-72cjogxz 3157 12 mesh mesh NN cord-015369-72cjogxz 3157 13 ( ( -LRB- cord-015369-72cjogxz 3157 14 436.5 436.5 CD cord-015369-72cjogxz 3157 15 148.8 148.8 CD cord-015369-72cjogxz 3157 16 square square JJ cord-015369-72cjogxz 3157 17 centimetres centimetre NNS cord-015369-72cjogxz 3157 18 ) ) -RRB- cord-015369-72cjogxz 3157 19 anchored anchor VBN cord-015369-72cjogxz 3157 20 by by IN cord-015369-72cjogxz 3157 21 transmuscular transmuscular JJ cord-015369-72cjogxz 3157 22 corner corner NN cord-015369-72cjogxz 3157 23 sutures suture NNS cord-015369-72cjogxz 3157 24 and and CC cord-015369-72cjogxz 3157 25 multiple multiple JJ cord-015369-72cjogxz 3157 26 spiral spiral JJ cord-015369-72cjogxz 3157 27 staples staple NNS cord-015369-72cjogxz 3157 28 . . . cord-015369-72cjogxz 3158 1 Perioperative perioperative JJ cord-015369-72cjogxz 3158 2 antibiotic antibiotic JJ cord-015369-72cjogxz 3158 3 prophylaxis prophylaxis NN cord-015369-72cjogxz 3158 4 was be VBD cord-015369-72cjogxz 3158 5 routinely routinely RB cord-015369-72cjogxz 3158 6 administered administer VBN cord-015369-72cjogxz 3158 7 . . . cord-015369-72cjogxz 3159 1 No no DT cord-015369-72cjogxz 3159 2 complications complication NNS cord-015369-72cjogxz 3159 3 occurred occur VBD cord-015369-72cjogxz 3159 4 in in IN cord-015369-72cjogxz 3159 5 the the DT cord-015369-72cjogxz 3159 6 early early JJ cord-015369-72cjogxz 3159 7 postoperative postoperative JJ cord-015369-72cjogxz 3159 8 course course NN cord-015369-72cjogxz 3159 9 , , , cord-015369-72cjogxz 3159 10 aside aside RB cord-015369-72cjogxz 3159 11 from from IN cord-015369-72cjogxz 3159 12 one one CD cord-015369-72cjogxz 3159 13 subfascial subfascial JJ cord-015369-72cjogxz 3159 14 hematoma hematoma NN cord-015369-72cjogxz 3159 15 ( ( -LRB- cord-015369-72cjogxz 3159 16 6.7 6.7 CD cord-015369-72cjogxz 3159 17 % % NN cord-015369-72cjogxz 3159 18 ) ) -RRB- cord-015369-72cjogxz 3159 19 . . . cord-015369-72cjogxz 3160 1 Mean mean JJ cord-015369-72cjogxz 3160 2 length length NN cord-015369-72cjogxz 3160 3 of of IN cord-015369-72cjogxz 3160 4 stay stay NN cord-015369-72cjogxz 3160 5 was be VBD cord-015369-72cjogxz 3160 6 8.1 8.1 CD cord-015369-72cjogxz 3160 7 AE AE NNP cord-015369-72cjogxz 3160 8 1.8 1.8 CD cord-015369-72cjogxz 3160 9 days day NNS cord-015369-72cjogxz 3160 10 . . . cord-015369-72cjogxz 3161 1 Highest high JJS cord-015369-72cjogxz 3161 2 c c NN cord-015369-72cjogxz 3161 3 - - HYPH cord-015369-72cjogxz 3161 4 reactive reactive JJ cord-015369-72cjogxz 3161 5 protein protein NN cord-015369-72cjogxz 3161 6 levels level NNS cord-015369-72cjogxz 3161 7 during during IN cord-015369-72cjogxz 3161 8 hospitalization hospitalization NN cord-015369-72cjogxz 3161 9 were be VBD cord-015369-72cjogxz 3161 10 7.4 7.4 CD cord-015369-72cjogxz 3161 11 AE AE NNP cord-015369-72cjogxz 3161 12 8.4 8.4 CD cord-015369-72cjogxz 3161 13 mg mg NNP cord-015369-72cjogxz 3161 14 / / SYM cord-015369-72cjogxz 3161 15 dl dl NNP cord-015369-72cjogxz 3161 16 . . . cord-015369-72cjogxz 3162 1 After after IN cord-015369-72cjogxz 3162 2 a a DT cord-015369-72cjogxz 3162 3 mean mean JJ cord-015369-72cjogxz 3162 4 follow follow NN cord-015369-72cjogxz 3162 5 - - HYPH cord-015369-72cjogxz 3162 6 up up NN cord-015369-72cjogxz 3162 7 of of IN cord-015369-72cjogxz 3162 8 19.8 19.8 CD cord-015369-72cjogxz 3162 9 AE AE NNP cord-015369-72cjogxz 3162 10 7.7 7.7 CD cord-015369-72cjogxz 3162 11 months month NNS cord-015369-72cjogxz 3162 12 , , , cord-015369-72cjogxz 3162 13 4 4 CD cord-015369-72cjogxz 3162 14 ( ( -LRB- cord-015369-72cjogxz 3162 15 26.7 26.7 CD cord-015369-72cjogxz 3162 16 % % NN cord-015369-72cjogxz 3162 17 ) ) -RRB- cord-015369-72cjogxz 3162 18 patients patient NNS cord-015369-72cjogxz 3162 19 developed develop VBD cord-015369-72cjogxz 3162 20 recurrent recurrent JJ cord-015369-72cjogxz 3162 21 hernias hernia NNS cord-015369-72cjogxz 3162 22 , , , cord-015369-72cjogxz 3162 23 which which WDT cord-015369-72cjogxz 3162 24 were be VBD cord-015369-72cjogxz 3162 25 repaired repair VBN cord-015369-72cjogxz 3162 26 in in IN cord-015369-72cjogxz 3162 27 3 3 CD cord-015369-72cjogxz 3162 28 cases case NNS cord-015369-72cjogxz 3162 29 ( ( -LRB- cord-015369-72cjogxz 3162 30 1 1 CD cord-015369-72cjogxz 3162 31 open open JJ cord-015369-72cjogxz 3162 32 , , , cord-015369-72cjogxz 3162 33 2 2 CD cord-015369-72cjogxz 3162 34 LIHR LIHR NNP cord-015369-72cjogxz 3162 35 ) ) -RRB- cord-015369-72cjogxz 3162 36 . . . cord-015369-72cjogxz 3163 1 Conclusions conclusion NNS cord-015369-72cjogxz 3163 2 . . . cord-015369-72cjogxz 3164 1 With with IN cord-015369-72cjogxz 3164 2 the the DT cord-015369-72cjogxz 3164 3 use use NN cord-015369-72cjogxz 3164 4 of of IN cord-015369-72cjogxz 3164 5 perioperative perioperative JJ cord-015369-72cjogxz 3164 6 antibiotic antibiotic JJ cord-015369-72cjogxz 3164 7 prophylaxis prophylaxis NN cord-015369-72cjogxz 3164 8 , , , cord-015369-72cjogxz 3164 9 LIHR LIHR NNP cord-015369-72cjogxz 3164 10 is be VBZ cord-015369-72cjogxz 3164 11 safe safe JJ cord-015369-72cjogxz 3164 12 in in IN cord-015369-72cjogxz 3164 13 patients patient NNS cord-015369-72cjogxz 3164 14 following follow VBG cord-015369-72cjogxz 3164 15 LTX LTX NNP cord-015369-72cjogxz 3164 16 . . . cord-015369-72cjogxz 3165 1 No no DT cord-015369-72cjogxz 3165 2 infectious infectious JJ cord-015369-72cjogxz 3165 3 complications complication NNS cord-015369-72cjogxz 3165 4 occurred occur VBD cord-015369-72cjogxz 3165 5 , , , cord-015369-72cjogxz 3165 6 however however RB cord-015369-72cjogxz 3165 7 27 27 CD cord-015369-72cjogxz 3165 8 % % NN cord-015369-72cjogxz 3165 9 of of IN cord-015369-72cjogxz 3165 10 our -PRON- PRP$ cord-015369-72cjogxz 3165 11 patients patient NNS cord-015369-72cjogxz 3165 12 developed develop VBD cord-015369-72cjogxz 3165 13 a a DT cord-015369-72cjogxz 3165 14 recurrent recurrent JJ cord-015369-72cjogxz 3165 15 hernia hernia NN cord-015369-72cjogxz 3165 16 after after IN cord-015369-72cjogxz 3165 17 a a DT cord-015369-72cjogxz 3165 18 mean mean JJ cord-015369-72cjogxz 3165 19 follow follow NN cord-015369-72cjogxz 3165 20 - - HYPH cord-015369-72cjogxz 3165 21 up up NN cord-015369-72cjogxz 3165 22 of of IN cord-015369-72cjogxz 3165 23 20 20 CD cord-015369-72cjogxz 3165 24 months month NNS cord-015369-72cjogxz 3165 25 . . . cord-015369-72cjogxz 3166 1 Added add VBN cord-015369-72cjogxz 3166 2 benefit benefit NN cord-015369-72cjogxz 3166 3 of of IN cord-015369-72cjogxz 3166 4 diagnostic diagnostic JJ cord-015369-72cjogxz 3166 5 laparoscopy laparoscopy NN cord-015369-72cjogxz 3166 6 in in IN cord-015369-72cjogxz 3166 7 patients patient NNS cord-015369-72cjogxz 3166 8 with with IN cord-015369-72cjogxz 3166 9 suspected suspect VBN cord-015369-72cjogxz 3166 10 acute acute JJ cord-015369-72cjogxz 3166 11 appendicitis appendicitis NN cord-015369-72cjogxz 3166 12 Methods method NNS cord-015369-72cjogxz 3166 13 . . . cord-015369-72cjogxz 3167 1 We -PRON- PRP cord-015369-72cjogxz 3167 2 defined define VBD cord-015369-72cjogxz 3167 3 a a DT cord-015369-72cjogxz 3167 4 clinical clinical JJ cord-015369-72cjogxz 3167 5 pathway pathway NN cord-015369-72cjogxz 3167 6 for for IN cord-015369-72cjogxz 3167 7 diagnosis diagnosis NN cord-015369-72cjogxz 3167 8 and and CC cord-015369-72cjogxz 3167 9 treatment treatment NN cord-015369-72cjogxz 3167 10 in in IN cord-015369-72cjogxz 3167 11 patients patient NNS cord-015369-72cjogxz 3167 12 with with IN cord-015369-72cjogxz 3167 13 suspected suspect VBN cord-015369-72cjogxz 3167 14 acute acute JJ cord-015369-72cjogxz 3167 15 appendicitis appendicitis NN cord-015369-72cjogxz 3167 16 . . . cord-015369-72cjogxz 3168 1 In in IN cord-015369-72cjogxz 3168 2 this this DT cord-015369-72cjogxz 3168 3 pathway pathway NN cord-015369-72cjogxz 3168 4 diagnostic diagnostic JJ cord-015369-72cjogxz 3168 5 laparoscopy laparoscopy NN cord-015369-72cjogxz 3168 6 is be VBZ cord-015369-72cjogxz 3168 7 an an DT cord-015369-72cjogxz 3168 8 early early JJ cord-015369-72cjogxz 3168 9 step step NN cord-015369-72cjogxz 3168 10 whereas whereas IN cord-015369-72cjogxz 3168 11 ultrasonography ultrasonography NN cord-015369-72cjogxz 3168 12 is be VBZ cord-015369-72cjogxz 3168 13 not not RB cord-015369-72cjogxz 3168 14 part part NN cord-015369-72cjogxz 3168 15 of of IN cord-015369-72cjogxz 3168 16 the the DT cord-015369-72cjogxz 3168 17 diagnostic diagnostic JJ cord-015369-72cjogxz 3168 18 steps step NNS cord-015369-72cjogxz 3168 19 . . . cord-015369-72cjogxz 3169 1 The the DT cord-015369-72cjogxz 3169 2 aim aim NN cord-015369-72cjogxz 3169 3 of of IN cord-015369-72cjogxz 3169 4 this this DT cord-015369-72cjogxz 3169 5 study study NN cord-015369-72cjogxz 3169 6 was be VBD cord-015369-72cjogxz 3169 7 to to TO cord-015369-72cjogxz 3169 8 know know VB cord-015369-72cjogxz 3169 9 the the DT cord-015369-72cjogxz 3169 10 positive positive JJ cord-015369-72cjogxz 3169 11 predictive predictive JJ cord-015369-72cjogxz 3169 12 value value NN cord-015369-72cjogxz 3169 13 for for IN cord-015369-72cjogxz 3169 14 acute acute JJ cord-015369-72cjogxz 3169 15 appendicitis appendicitis NN cord-015369-72cjogxz 3169 16 and and CC cord-015369-72cjogxz 3169 17 experience experience VB cord-015369-72cjogxz 3169 18 the the DT cord-015369-72cjogxz 3169 19 outcome outcome NN cord-015369-72cjogxz 3169 20 of of IN cord-015369-72cjogxz 3169 21 these these DT cord-015369-72cjogxz 3169 22 patients patient NNS cord-015369-72cjogxz 3169 23 concerning concern VBG cord-015369-72cjogxz 3169 24 the the DT cord-015369-72cjogxz 3169 25 diagnostic diagnostic JJ cord-015369-72cjogxz 3169 26 value value NN cord-015369-72cjogxz 3169 27 of of IN cord-015369-72cjogxz 3169 28 a a DT cord-015369-72cjogxz 3169 29 laparoscopy laparoscopy NN cord-015369-72cjogxz 3169 30 . . . cord-015369-72cjogxz 3170 1 Results result NNS cord-015369-72cjogxz 3170 2 . . . cord-015369-72cjogxz 3171 1 Between between IN cord-015369-72cjogxz 3171 2 1 1 CD cord-015369-72cjogxz 3171 3 Apr. April NNP cord-015369-72cjogxz 3171 4 2000 2000 CD cord-015369-72cjogxz 3171 5 and and CC cord-015369-72cjogxz 3171 6 31 31 CD cord-015369-72cjogxz 3171 7 Dec. December NNP cord-015369-72cjogxz 3171 8 2008 2008 CD cord-015369-72cjogxz 3171 9 , , , cord-015369-72cjogxz 3171 10 897 897 CD cord-015369-72cjogxz 3171 11 patients patient NNS cord-015369-72cjogxz 3171 12 were be VBD cord-015369-72cjogxz 3171 13 prospectively prospectively RB cord-015369-72cjogxz 3171 14 recorded record VBN cord-015369-72cjogxz 3171 15 . . . cord-015369-72cjogxz 3172 1 The the DT cord-015369-72cjogxz 3172 2 correct correct JJ cord-015369-72cjogxz 3172 3 diagnosis diagnosis NN cord-015369-72cjogxz 3172 4 was be VBD cord-015369-72cjogxz 3172 5 found find VBN cord-015369-72cjogxz 3172 6 in in IN cord-015369-72cjogxz 3172 7 756 756 CD cord-015369-72cjogxz 3172 8 ( ( -LRB- cord-015369-72cjogxz 3172 9 84 84 CD cord-015369-72cjogxz 3172 10 % % NN cord-015369-72cjogxz 3172 11 ) ) -RRB- cord-015369-72cjogxz 3172 12 patients patient NNS cord-015369-72cjogxz 3172 13 . . . cord-015369-72cjogxz 3173 1 In in IN cord-015369-72cjogxz 3173 2 141 141 CD cord-015369-72cjogxz 3173 3 ( ( -LRB- cord-015369-72cjogxz 3173 4 16 16 CD cord-015369-72cjogxz 3173 5 % % NN cord-015369-72cjogxz 3173 6 ) ) -RRB- cord-015369-72cjogxz 3173 7 patients patient NNS cord-015369-72cjogxz 3173 8 either either CC cord-015369-72cjogxz 3173 9 the the DT cord-015369-72cjogxz 3173 10 cause cause NN cord-015369-72cjogxz 3173 11 of of IN cord-015369-72cjogxz 3173 12 the the DT cord-015369-72cjogxz 3173 13 abdominal abdominal JJ cord-015369-72cjogxz 3173 14 pain pain NN cord-015369-72cjogxz 3173 15 remained remain VBD cord-015369-72cjogxz 3173 16 unclear unclear JJ cord-015369-72cjogxz 3173 17 ( ( -LRB- cord-015369-72cjogxz 3173 18 27 27 CD cord-015369-72cjogxz 3173 19 patients patient NNS cord-015369-72cjogxz 3173 20 ; ; : cord-015369-72cjogxz 3173 21 3 3 CD cord-015369-72cjogxz 3173 22 % % NN cord-015369-72cjogxz 3173 23 ) ) -RRB- cord-015369-72cjogxz 3173 24 or or CC cord-015369-72cjogxz 3173 25 a a DT cord-015369-72cjogxz 3173 26 different different JJ cord-015369-72cjogxz 3173 27 diagnosis diagnosis NN cord-015369-72cjogxz 3173 28 was be VBD cord-015369-72cjogxz 3173 29 found find VBN cord-015369-72cjogxz 3173 30 ( ( -LRB- cord-015369-72cjogxz 3173 31 114 114 CD cord-015369-72cjogxz 3173 32 patients patient NNS cord-015369-72cjogxz 3173 33 ; ; : cord-015369-72cjogxz 3173 34 13 13 CD cord-015369-72cjogxz 3173 35 % % NN cord-015369-72cjogxz 3173 36 ) ) -RRB- cord-015369-72cjogxz 3173 37 . . . cord-015369-72cjogxz 3174 1 In in IN cord-015369-72cjogxz 3174 2 these these DT cord-015369-72cjogxz 3174 3 114 114 CD cord-015369-72cjogxz 3174 4 patients patient NNS cord-015369-72cjogxz 3174 5 a a DT cord-015369-72cjogxz 3174 6 list list NN cord-015369-72cjogxz 3174 7 of of IN cord-015369-72cjogxz 3174 8 16 16 CD cord-015369-72cjogxz 3174 9 different different JJ cord-015369-72cjogxz 3174 10 diagnoses diagnosis NNS cord-015369-72cjogxz 3174 11 was be VBD cord-015369-72cjogxz 3174 12 found find VBN cord-015369-72cjogxz 3174 13 . . . cord-015369-72cjogxz 3175 1 In in IN cord-015369-72cjogxz 3175 2 ten ten CD cord-015369-72cjogxz 3175 3 patients patient NNS cord-015369-72cjogxz 3175 4 ( ( -LRB- cord-015369-72cjogxz 3175 5 1.3 1.3 CD cord-015369-72cjogxz 3175 6 % % NN cord-015369-72cjogxz 3175 7 ) ) -RRB- cord-015369-72cjogxz 3175 8 even even RB cord-015369-72cjogxz 3175 9 a a DT cord-015369-72cjogxz 3175 10 malignoma malignoma NN cord-015369-72cjogxz 3175 11 was be VBD cord-015369-72cjogxz 3175 12 found find VBN cord-015369-72cjogxz 3175 13 . . . cord-015369-72cjogxz 3176 1 Conclusions conclusion NNS cord-015369-72cjogxz 3176 2 . . . cord-015369-72cjogxz 3177 1 Our -PRON- PRP$ cord-015369-72cjogxz 3177 2 defined define VBN cord-015369-72cjogxz 3177 3 pathway pathway NN cord-015369-72cjogxz 3177 4 for for IN cord-015369-72cjogxz 3177 5 diagnosis diagnosis NN cord-015369-72cjogxz 3177 6 and and CC cord-015369-72cjogxz 3177 7 treatment treatment NN cord-015369-72cjogxz 3177 8 in in IN cord-015369-72cjogxz 3177 9 patients patient NNS cord-015369-72cjogxz 3177 10 with with IN cord-015369-72cjogxz 3177 11 suspected suspect VBN cord-015369-72cjogxz 3177 12 acute acute JJ cord-015369-72cjogxz 3177 13 appendicitis appendicitis NN cord-015369-72cjogxz 3177 14 allows allow VBZ cord-015369-72cjogxz 3177 15 finding find VBG cord-015369-72cjogxz 3177 16 the the DT cord-015369-72cjogxz 3177 17 cause cause NN cord-015369-72cjogxz 3177 18 of of IN cord-015369-72cjogxz 3177 19 the the DT cord-015369-72cjogxz 3177 20 abdominal abdominal JJ cord-015369-72cjogxz 3177 21 complaints complaint NNS cord-015369-72cjogxz 3177 22 in in IN cord-015369-72cjogxz 3177 23 97 97 CD cord-015369-72cjogxz 3177 24 % % NN cord-015369-72cjogxz 3177 25 and and CC cord-015369-72cjogxz 3177 26 in in IN cord-015369-72cjogxz 3177 27 84 84 CD cord-015369-72cjogxz 3177 28 % % NN cord-015369-72cjogxz 3177 29 acute acute JJ cord-015369-72cjogxz 3177 30 appendicitis appendicitis NN cord-015369-72cjogxz 3177 31 was be VBD cord-015369-72cjogxz 3177 32 confirmed confirm VBN cord-015369-72cjogxz 3177 33 . . . cord-015369-72cjogxz 3178 1 Due due IN cord-015369-72cjogxz 3178 2 to to IN cord-015369-72cjogxz 3178 3 consequent consequent JJ cord-015369-72cjogxz 3178 4 diagnostic diagnostic JJ cord-015369-72cjogxz 3178 5 laparoscopy laparoscopy NN cord-015369-72cjogxz 3178 6 a a DT cord-015369-72cjogxz 3178 7 broad broad JJ cord-015369-72cjogxz 3178 8 list list NN cord-015369-72cjogxz 3178 9 of of IN cord-015369-72cjogxz 3178 10 differential differential JJ cord-015369-72cjogxz 3178 11 diagnosis diagnosis NN cord-015369-72cjogxz 3178 12 was be VBD cord-015369-72cjogxz 3178 13 found find VBN cord-015369-72cjogxz 3178 14 including include VBG cord-015369-72cjogxz 3178 15 malignant malignant JJ cord-015369-72cjogxz 3178 16 tumours tumour NNS cord-015369-72cjogxz 3178 17 in in IN cord-015369-72cjogxz 3178 18 1.3 1.3 CD cord-015369-72cjogxz 3178 19 % % NN cord-015369-72cjogxz 3178 20 . . . cord-015369-72cjogxz 3179 1 Therefore therefore RB cord-015369-72cjogxz 3179 2 , , , cord-015369-72cjogxz 3179 3 diagnostic diagnostic JJ cord-015369-72cjogxz 3179 4 laparoscopy laparoscopy NN cord-015369-72cjogxz 3179 5 should should MD cord-015369-72cjogxz 3179 6 be be VB cord-015369-72cjogxz 3179 7 an an DT cord-015369-72cjogxz 3179 8 early early JJ cord-015369-72cjogxz 3179 9 diagnostic diagnostic JJ cord-015369-72cjogxz 3179 10 step step NN cord-015369-72cjogxz 3179 11 in in IN cord-015369-72cjogxz 3179 12 patients patient NNS cord-015369-72cjogxz 3179 13 with with IN cord-015369-72cjogxz 3179 14 suspected suspect VBN cord-015369-72cjogxz 3179 15 acute acute JJ cord-015369-72cjogxz 3179 16 appendicitis appendicitis NN cord-015369-72cjogxz 3179 17 . . . cord-015369-72cjogxz 3180 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 3180 2 . . . cord-015369-72cjogxz 3181 1 Der Der NNP cord-015369-72cjogxz 3181 2 Spitalaufenthalt Spitalaufenthalt NNP cord-015369-72cjogxz 3181 3 betrug betrug NNP cord-015369-72cjogxz 3181 4 zwischen zwischen NNP cord-015369-72cjogxz 3181 5 2 2 CD cord-015369-72cjogxz 3181 6 und und IN cord-015369-72cjogxz 3181 7 4 4 CD cord-015369-72cjogxz 3181 8 Tagen Tagen NNP cord-015369-72cjogxz 3181 9 ( ( -LRB- cord-015369-72cjogxz 3181 10 Mittelwert Mittelwert NNP cord-015369-72cjogxz 3181 11 : : : cord-015369-72cjogxz 3181 12 2,9 2,9 CD cord-015369-72cjogxz 3181 13 Tage Tage NNP cord-015369-72cjogxz 3181 14 ) ) -RRB- cord-015369-72cjogxz 3181 15 . . . cord-015369-72cjogxz 3182 1 In in IN cord-015369-72cjogxz 3182 2 30,4 30,4 CD cord-015369-72cjogxz 3182 3 % % NN cord-015369-72cjogxz 3182 4 der der NNP cord-015369-72cjogxz 3182 5 Fälle Fälle NNP cord-015369-72cjogxz 3182 6 war war NN cord-015369-72cjogxz 3182 7 kein kein NN cord-015369-72cjogxz 3182 8 Schmerzmittel Schmerzmittel NNP cord-015369-72cjogxz 3182 9 notwendig notwendig NNP cord-015369-72cjogxz 3182 10 , , , cord-015369-72cjogxz 3182 11 45,7 45,7 CD cord-015369-72cjogxz 3182 12 % % NN cord-015369-72cjogxz 3182 13 benötigten benötigten NNP cord-015369-72cjogxz 3182 14 Schmerzmittel Schmerzmittel NNP cord-015369-72cjogxz 3182 15 bis bis NNP cord-015369-72cjogxz 3182 16 zu zu NNP cord-015369-72cjogxz 3182 17 5 5 CD cord-015369-72cjogxz 3182 18 Tage Tage NNP cord-015369-72cjogxz 3182 19 , , , cord-015369-72cjogxz 3183 1 23,9 23,9 CD cord-015369-72cjogxz 3183 2 % % NN cord-015369-72cjogxz 3183 3 länger länger NNP cord-015369-72cjogxz 3184 1 ( ( -LRB- cord-015369-72cjogxz 3184 2 Mittelwert Mittelwert NNP cord-015369-72cjogxz 3184 3 : : : cord-015369-72cjogxz 3184 4 3,9 3,9 CD cord-015369-72cjogxz 3184 5 Tage Tage NNP cord-015369-72cjogxz 3184 6 ) ) -RRB- cord-015369-72cjogxz 3184 7 . . . cord-015369-72cjogxz 3185 1 Die die VB cord-015369-72cjogxz 3185 2 Hauptbeschwerden Hauptbeschwerden NNP cord-015369-72cjogxz 3185 3 reduzierten reduzierten VBD cord-015369-72cjogxz 3185 4 sich sich NNP cord-015369-72cjogxz 3185 5 bei bei NNP cord-015369-72cjogxz 3185 6 Blutungen Blutungen NNP cord-015369-72cjogxz 3185 7 von von NNP cord-015369-72cjogxz 3186 1 70,65 70,65 CD cord-015369-72cjogxz 3186 2 % % NN cord-015369-72cjogxz 3186 3 ( ( -LRB- cord-015369-72cjogxz 3186 4 präoperativ präoperativ NN cord-015369-72cjogxz 3186 5 ) ) -RRB- cord-015369-72cjogxz 3187 1 auf auf NNP cord-015369-72cjogxz 3187 2 9,84 9,84 CD cord-015369-72cjogxz 3187 3 % % NN cord-015369-72cjogxz 3187 4 ( ( -LRB- cord-015369-72cjogxz 3187 5 6 6 CD cord-015369-72cjogxz 3187 6 Monate Monate NNP cord-015369-72cjogxz 3187 7 postoperativ postoperativ NN cord-015369-72cjogxz 3187 8 ) ) -RRB- cord-015369-72cjogxz 3187 9 , , , cord-015369-72cjogxz 3187 10 bei bei NNP cord-015369-72cjogxz 3187 11 durch durch NNP cord-015369-72cjogxz 3187 12 Prolaps Prolaps NNP cord-015369-72cjogxz 3187 13 hervorgerufener hervorgerufener NN cord-015369-72cjogxz 3187 14 verschmutzter verschmutzter NN cord-015369-72cjogxz 3187 15 Unterwäsche Unterwäsche NNP cord-015369-72cjogxz 3187 16 von von NNP cord-015369-72cjogxz 3187 17 52,17 52,17 CD cord-015369-72cjogxz 3187 18 % % NN cord-015369-72cjogxz 3187 19 auf auf NNP cord-015369-72cjogxz 3187 20 3,28 3,28 CD cord-015369-72cjogxz 3187 21 % % NN cord-015369-72cjogxz 3187 22 . . . cord-015369-72cjogxz 3188 1 Von Von NNP cord-015369-72cjogxz 3188 2 den den NNP cord-015369-72cjogxz 3189 1 bis bis NNP cord-015369-72cjogxz 3189 2 jetzt jetzt NNP cord-015369-72cjogxz 3189 3 nachuntersuchten nachuntersuchten NNP cord-015369-72cjogxz 3190 1 PatientInnen PatientInnen NNP cord-015369-72cjogxz 3190 2 gaben gaben NNP cord-015369-72cjogxz 3190 3 nach nach NNP cord-015369-72cjogxz 3190 4 6 6 CD cord-015369-72cjogxz 3191 1 Monaten Monaten NNP cord-015369-72cjogxz 3191 2 91,8 91,8 CD cord-015369-72cjogxz 3191 3 % % NN cord-015369-72cjogxz 3191 4 eine eine NNP cord-015369-72cjogxz 3191 5 hohe hohe NNP cord-015369-72cjogxz 3191 6 Zufriedenheit Zufriedenheit NNP cord-015369-72cjogxz 3191 7 und und XX cord-015369-72cjogxz 3192 1 Beschwerdefreiheit Beschwerdefreiheit NNP cord-015369-72cjogxz 3192 2 an an DT cord-015369-72cjogxz 3192 3 . . . cord-015369-72cjogxz 3193 1 Bis Bis NNP cord-015369-72cjogxz 3193 2 jetzt jetzt NNP cord-015369-72cjogxz 3193 3 erfolgte erfolgte NN cord-015369-72cjogxz 3193 4 eine eine NNP cord-015369-72cjogxz 3193 5 Rezidivoperation Rezidivoperation NNP cord-015369-72cjogxz 3193 6 , , , cord-015369-72cjogxz 3193 7 vier vier NNP cord-015369-72cjogxz 3193 8 weitere weitere JJ cord-015369-72cjogxz 3193 9 wegen wegen NNP cord-015369-72cjogxz 3193 10 erneuten erneuten NNP cord-015369-72cjogxz 3193 11 Prolaps Prolaps NNP cord-015369-72cjogxz 3193 12 folgen folgen NNS cord-015369-72cjogxz 3193 13 . . . cord-015369-72cjogxz 3194 1 Mit Mit NNP cord-015369-72cjogxz 3194 2 Ausnahme Ausnahme NNP cord-015369-72cjogxz 3194 3 von von NNP cord-015369-72cjogxz 3194 4 zwei zwei NNP cord-015369-72cjogxz 3194 5 postoperativ postoperativ NNP cord-015369-72cjogxz 3194 6 aufgetretenen aufgetretenen NNP cord-015369-72cjogxz 3195 1 Abszessen Abszessen NNP cord-015369-72cjogxz 3195 2 mit mit NNP cord-015369-72cjogxz 3195 3 Fistelbildung Fistelbildung NNP cord-015369-72cjogxz 3195 4 gab gab NNP cord-015369-72cjogxz 3196 1 es es NNP cord-015369-72cjogxz 3196 2 bislang bislang NNP cord-015369-72cjogxz 3196 3 keine keine NNP cord-015369-72cjogxz 3196 4 nennenswerten nennenswerten NNP cord-015369-72cjogxz 3196 5 Komplikationen Komplikationen NNP cord-015369-72cjogxz 3196 6 . . . cord-015369-72cjogxz 3197 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 3197 2 . . . cord-015369-72cjogxz 3198 1 Obwohl Obwohl NNP cord-015369-72cjogxz 3198 2 Langzeitergebnisse Langzeitergebnisse NNP cord-015369-72cjogxz 3198 3 noch noch NNP cord-015369-72cjogxz 3198 4 ausstehen ausstehen NNP cord-015369-72cjogxz 3199 1 , , , cord-015369-72cjogxz 3199 2 ist ist FW cord-015369-72cjogxz 3199 3 diese diese NNP cord-015369-72cjogxz 3199 4 Methode Methode NNP cord-015369-72cjogxz 3199 5 der der NNP cord-015369-72cjogxz 3199 6 Hämorridenoperationen Hämorridenoperationen NNP cord-015369-72cjogxz 3199 7 als als NN cord-015369-72cjogxz 3199 8 komplikationsarm komplikationsarm NNP cord-015369-72cjogxz 3199 9 , , , cord-015369-72cjogxz 3199 10 sphinkterschonend sphinkterschonend NNP cord-015369-72cjogxz 3199 11 und und NNP cord-015369-72cjogxz 3199 12 somit somit NNP cord-015369-72cjogxz 3199 13 sehr sehr NNP cord-015369-72cjogxz 3199 14 empfehlenswert empfehlenswert NNP cord-015369-72cjogxz 3199 15 zu zu NNP cord-015369-72cjogxz 3199 16 bewerten bewerten NNP cord-015369-72cjogxz 3199 17 . . . cord-015369-72cjogxz 3200 1 Sie Sie NNP cord-015369-72cjogxz 3200 2 zeichnet zeichnet NNP cord-015369-72cjogxz 3200 3 sich sich NNP cord-015369-72cjogxz 3201 1 zudem zudem NNP cord-015369-72cjogxz 3201 2 aus aus NNP cord-015369-72cjogxz 3201 3 durch durch NNP cord-015369-72cjogxz 3202 1 eine eine NNP cord-015369-72cjogxz 3202 2 hohe hohe NNP cord-015369-72cjogxz 3202 3 PatientInnenzufriedenheit PatientInnenzufriedenheit NNP cord-015369-72cjogxz 3202 4 , , , cord-015369-72cjogxz 3202 5 einen einen NNP cord-015369-72cjogxz 3202 6 kurzen kurzen NNP cord-015369-72cjogxz 3202 7 Krankenhausaufenthalt Krankenhausaufenthalt NNP cord-015369-72cjogxz 3202 8 , , , cord-015369-72cjogxz 3202 9 einen einen VB cord-015369-72cjogxz 3202 10 geringen geringen NNP cord-015369-72cjogxz 3202 11 Schmerzmittelbedarf Schmerzmittelbedarf NNP cord-015369-72cjogxz 3202 12 und und XX cord-015369-72cjogxz 3203 1 eine eine NNP cord-015369-72cjogxz 3203 2 rasche rasche NNP cord-015369-72cjogxz 3203 3 Reintegration Reintegration NNP cord-015369-72cjogxz 3203 4 in in IN cord-015369-72cjogxz 3203 5 den den NNP cord-015369-72cjogxz 3203 6 Alltags Alltags NNP cord-015369-72cjogxz 3203 7 - - HYPH cord-015369-72cjogxz 3203 8 und und NNP cord-015369-72cjogxz 3203 9 Arbeitsprozess Arbeitsprozess NNP cord-015369-72cjogxz 3203 10 . . . cord-015369-72cjogxz 3204 1 Observational observational JJ cord-015369-72cjogxz 3204 2 study study NN cord-015369-72cjogxz 3204 3 on on IN cord-015369-72cjogxz 3204 4 grade grade NN cord-015369-72cjogxz 3204 5 - - HYPH cord-015369-72cjogxz 3204 6 dependent dependent JJ cord-015369-72cjogxz 3204 7 treatment treatment NN cord-015369-72cjogxz 3204 8 for for IN cord-015369-72cjogxz 3204 9 hemorrhoidal hemorrhoidal JJ cord-015369-72cjogxz 3204 10 diseasea diseasea NNP cord-015369-72cjogxz 3204 11 single single JJ cord-015369-72cjogxz 3204 12 center center NN cord-015369-72cjogxz 3204 13 experience experience NN cord-015369-72cjogxz 3204 14 Background Background NNP cord-015369-72cjogxz 3204 15 . . . cord-015369-72cjogxz 3205 1 Hemorrhoidal hemorrhoidal JJ cord-015369-72cjogxz 3205 2 disease disease NN cord-015369-72cjogxz 3205 3 is be VBZ cord-015369-72cjogxz 3205 4 one one CD cord-015369-72cjogxz 3205 5 of of IN cord-015369-72cjogxz 3205 6 the the DT cord-015369-72cjogxz 3205 7 most most RBS cord-015369-72cjogxz 3205 8 common common JJ cord-015369-72cjogxz 3205 9 health health NN cord-015369-72cjogxz 3205 10 disorders disorder NNS cord-015369-72cjogxz 3205 11 in in IN cord-015369-72cjogxz 3205 12 Western western JJ cord-015369-72cjogxz 3205 13 civilization civilization NN cord-015369-72cjogxz 3205 14 . . . cord-015369-72cjogxz 3206 1 The the DT cord-015369-72cjogxz 3206 2 aim aim NN cord-015369-72cjogxz 3206 3 of of IN cord-015369-72cjogxz 3206 4 this this DT cord-015369-72cjogxz 3206 5 study study NN cord-015369-72cjogxz 3206 6 was be VBD cord-015369-72cjogxz 3206 7 to to TO cord-015369-72cjogxz 3206 8 retrospectively retrospectively RB cord-015369-72cjogxz 3206 9 analyze analyze VB cord-015369-72cjogxz 3206 10 the the DT cord-015369-72cjogxz 3206 11 outcome outcome NN cord-015369-72cjogxz 3206 12 of of IN cord-015369-72cjogxz 3206 13 grade grade NN cord-015369-72cjogxz 3206 14 - - HYPH cord-015369-72cjogxz 3206 15 dependent dependent JJ cord-015369-72cjogxz 3206 16 treatment treatment NN cord-015369-72cjogxz 3206 17 of of IN cord-015369-72cjogxz 3206 18 hemorrhoidal hemorrhoidal JJ cord-015369-72cjogxz 3206 19 disease disease NN cord-015369-72cjogxz 3206 20 ( ( -LRB- cord-015369-72cjogxz 3206 21 I I NNP cord-015369-72cjogxz 3206 22 - - HYPH cord-015369-72cjogxz 3206 23 IV IV NNP cord-015369-72cjogxz 3206 24 ) ) -RRB- cord-015369-72cjogxz 3206 25 in in IN cord-015369-72cjogxz 3206 26 a a DT cord-015369-72cjogxz 3206 27 single single JJ cord-015369-72cjogxz 3206 28 center center NN cord-015369-72cjogxz 3206 29 . . . cord-015369-72cjogxz 3207 1 Methods method NNS cord-015369-72cjogxz 3207 2 . . . cord-015369-72cjogxz 3208 1 All all DT cord-015369-72cjogxz 3208 2 patients patient NNS cord-015369-72cjogxz 3208 3 suffering suffer VBG cord-015369-72cjogxz 3208 4 from from IN cord-015369-72cjogxz 3208 5 hemorrhoidal hemorrhoidal JJ cord-015369-72cjogxz 3208 6 disease disease NN cord-015369-72cjogxz 3208 7 referred refer VBD cord-015369-72cjogxz 3208 8 to to IN cord-015369-72cjogxz 3208 9 our -PRON- PRP$ cord-015369-72cjogxz 3208 10 unit unit NN cord-015369-72cjogxz 3208 11 between between IN cord-015369-72cjogxz 3208 12 July July NNP cord-015369-72cjogxz 3208 13 2001 2001 CD cord-015369-72cjogxz 3208 14 and and CC cord-015369-72cjogxz 3208 15 December December NNP cord-015369-72cjogxz 3208 16 2005 2005 CD cord-015369-72cjogxz 3208 17 were be VBD cord-015369-72cjogxz 3208 18 included include VBN cord-015369-72cjogxz 3208 19 in in IN cord-015369-72cjogxz 3208 20 this this DT cord-015369-72cjogxz 3208 21 analysis analysis NN cord-015369-72cjogxz 3208 22 . . . cord-015369-72cjogxz 3209 1 The the DT cord-015369-72cjogxz 3209 2 patients patient NNS cord-015369-72cjogxz 3209 3 ' ' POS cord-015369-72cjogxz 3209 4 medical medical JJ cord-015369-72cjogxz 3209 5 records record NNS cord-015369-72cjogxz 3209 6 were be VBD cord-015369-72cjogxz 3209 7 studied study VBN cord-015369-72cjogxz 3209 8 in in IN cord-015369-72cjogxz 3209 9 detail detail NN cord-015369-72cjogxz 3209 10 . . . cord-015369-72cjogxz 3210 1 A a DT cord-015369-72cjogxz 3210 2 standardized standardized JJ cord-015369-72cjogxz 3210 3 telephone telephone NN cord-015369-72cjogxz 3210 4 interview interview NN cord-015369-72cjogxz 3210 5 was be VBD cord-015369-72cjogxz 3210 6 conducted conduct VBN cord-015369-72cjogxz 3210 7 in in IN cord-015369-72cjogxz 3210 8 all all DT cord-015369-72cjogxz 3210 9 patients patient NNS cord-015369-72cjogxz 3210 10 who who WP cord-015369-72cjogxz 3210 11 had have VBD cord-015369-72cjogxz 3210 12 open open JJ cord-015369-72cjogxz 3210 13 hemorrhoidectomy hemorrhoidectomy NN cord-015369-72cjogxz 3210 14 or or CC cord-015369-72cjogxz 3210 15 stapled staple VBD cord-015369-72cjogxz 3210 16 hemorrhoidopexy hemorrhoidopexy NNP cord-015369-72cjogxz 3210 17 . . . cord-015369-72cjogxz 3211 1 Results result NNS cord-015369-72cjogxz 3211 2 . . . cord-015369-72cjogxz 3212 1 A a DT cord-015369-72cjogxz 3212 2 total total NN cord-015369-72cjogxz 3212 3 of of IN cord-015369-72cjogxz 3212 4 668 668 CD cord-015369-72cjogxz 3212 5 patients patient NNS cord-015369-72cjogxz 3212 6 ( ( -LRB- cord-015369-72cjogxz 3212 7 284 284 CD cord-015369-72cjogxz 3212 8 female female JJ cord-015369-72cjogxz 3212 9 , , , cord-015369-72cjogxz 3212 10 384 384 CD cord-015369-72cjogxz 3212 11 male male NN cord-015369-72cjogxz 3212 12 ; ; : cord-015369-72cjogxz 3212 13 mean mean VB cord-015369-72cjogxz 3212 14 age age NN cord-015369-72cjogxz 3212 15 52.2 52.2 CD cord-015369-72cjogxz 3212 16 , , , cord-015369-72cjogxz 3212 17 range range VBP cord-015369-72cjogxz 3212 18 17 17 CD cord-015369-72cjogxz 3212 19 - - SYM cord-015369-72cjogxz 3212 20 94 94 CD cord-015369-72cjogxz 3212 21 years year NNS cord-015369-72cjogxz 3212 22 ) ) -RRB- cord-015369-72cjogxz 3212 23 were be VBD cord-015369-72cjogxz 3212 24 assessed assess VBN cord-015369-72cjogxz 3212 25 . . . cord-015369-72cjogxz 3213 1 Conservative conservative JJ cord-015369-72cjogxz 3213 2 treatment treatment NN cord-015369-72cjogxz 3213 3 was be VBD cord-015369-72cjogxz 3213 4 applied apply VBN cord-015369-72cjogxz 3213 5 in in IN cord-015369-72cjogxz 3213 6 281 281 CD cord-015369-72cjogxz 3213 7 ( ( -LRB- cord-015369-72cjogxz 3213 8 42.1 42.1 CD cord-015369-72cjogxz 3213 9 % % NN cord-015369-72cjogxz 3213 10 ) ) -RRB- cord-015369-72cjogxz 3213 11 cases case NNS cord-015369-72cjogxz 3213 12 , , , cord-015369-72cjogxz 3213 13 while while IN cord-015369-72cjogxz 3213 14 surgery surgery NN cord-015369-72cjogxz 3213 15 was be VBD cord-015369-72cjogxz 3213 16 performed perform VBN cord-015369-72cjogxz 3213 17 in in IN cord-015369-72cjogxz 3213 18 387 387 CD cord-015369-72cjogxz 3213 19 patients patient NNS cord-015369-72cjogxz 3213 20 ( ( -LRB- cord-015369-72cjogxz 3213 21 57.9 57.9 CD cord-015369-72cjogxz 3213 22 % % NN cord-015369-72cjogxz 3213 23 ) ) -RRB- cord-015369-72cjogxz 3213 24 following follow VBG cord-015369-72cjogxz 3213 25 a a DT cord-015369-72cjogxz 3213 26 grade grade NN cord-015369-72cjogxz 3213 27 - - HYPH cord-015369-72cjogxz 3213 28 dependent dependent JJ cord-015369-72cjogxz 3213 29 strategy strategy NN cord-015369-72cjogxz 3213 30 . . . cord-015369-72cjogxz 3214 1 Most Most JJS cord-015369-72cjogxz 3214 2 common common JJ cord-015369-72cjogxz 3214 3 comorbidities comorbiditie NNS cord-015369-72cjogxz 3214 4 were be VBD cord-015369-72cjogxz 3214 5 skin skin NN cord-015369-72cjogxz 3214 6 tags tag NNS cord-015369-72cjogxz 3214 7 and and CC cord-015369-72cjogxz 3214 8 simultaneous simultaneous JJ cord-015369-72cjogxz 3214 9 mucosal mucosal JJ cord-015369-72cjogxz 3214 10 prolapse prolapse NN cord-015369-72cjogxz 3214 11 . . . cord-015369-72cjogxz 3215 1 Postoperative postoperative JJ cord-015369-72cjogxz 3215 2 complications complication NNS cord-015369-72cjogxz 3215 3 comprised comprise VBD cord-015369-72cjogxz 3215 4 pain pain NN cord-015369-72cjogxz 3215 5 ( ( -LRB- cord-015369-72cjogxz 3215 6 8.1 8.1 CD cord-015369-72cjogxz 3215 7 % % NN cord-015369-72cjogxz 3215 8 ) ) -RRB- cord-015369-72cjogxz 3215 9 , , , cord-015369-72cjogxz 3215 10 bleeding bleed VBG cord-015369-72cjogxz 3215 11 ( ( -LRB- cord-015369-72cjogxz 3215 12 9.1 9.1 CD cord-015369-72cjogxz 3215 13 % % NN cord-015369-72cjogxz 3215 14 ) ) -RRB- cord-015369-72cjogxz 3215 15 and and CC cord-015369-72cjogxz 3215 16 fecal fecal JJ cord-015369-72cjogxz 3215 17 incontinence incontinence NN cord-015369-72cjogxz 3215 18 ( ( -LRB- cord-015369-72cjogxz 3215 19 3.4 3.4 CD cord-015369-72cjogxz 3215 20 % % NN cord-015369-72cjogxz 3215 21 ) ) -RRB- cord-015369-72cjogxz 3215 22 . . . cord-015369-72cjogxz 3216 1 Patients patient NNS cord-015369-72cjogxz 3216 2 undergoing undergo VBG cord-015369-72cjogxz 3216 3 stapled staple VBN cord-015369-72cjogxz 3216 4 hemorrhoidopexy hemorrhoidopexy NNP cord-015369-72cjogxz 3216 5 showed show VBD cord-015369-72cjogxz 3216 6 significantly significantly RB cord-015369-72cjogxz 3216 7 higher high JJR cord-015369-72cjogxz 3216 8 recurrence recurrence NN cord-015369-72cjogxz 3216 9 rates rate NNS cord-015369-72cjogxz 3216 10 than than IN cord-015369-72cjogxz 3216 11 after after IN cord-015369-72cjogxz 3216 12 open open JJ cord-015369-72cjogxz 3216 13 hemorrhoidectomy hemorrhoidectomy NN cord-015369-72cjogxz 3216 14 ( ( -LRB- cord-015369-72cjogxz 3216 15 10 10 CD cord-015369-72cjogxz 3216 16 % % NN cord-015369-72cjogxz 3216 17 vs. vs. CC cord-015369-72cjogxz 3216 18 0 0 CD cord-015369-72cjogxz 3216 19 % % NN cord-015369-72cjogxz 3216 20 , , , cord-015369-72cjogxz 3216 21 p p NN cord-015369-72cjogxz 3216 22 ¼ ¼ CD cord-015369-72cjogxz 3216 23 0.048 0.048 CD cord-015369-72cjogxz 3216 24 ) ) -RRB- cord-015369-72cjogxz 3216 25 . . . cord-015369-72cjogxz 3217 1 Urgency Urgency NNP cord-015369-72cjogxz 3217 2 was be VBD cord-015369-72cjogxz 3217 3 more more RBR cord-015369-72cjogxz 3217 4 common common JJ cord-015369-72cjogxz 3217 5 in in IN cord-015369-72cjogxz 3217 6 the the DT cord-015369-72cjogxz 3217 7 stapled stapled JJ cord-015369-72cjogxz 3217 8 hemorrhoidopexy hemorrhoidopexy NNP cord-015369-72cjogxz 3217 9 group group NN cord-015369-72cjogxz 3217 10 ( ( -LRB- cord-015369-72cjogxz 3217 11 34.5 34.5 CD cord-015369-72cjogxz 3217 12 % % NN cord-015369-72cjogxz 3217 13 vs. vs. NN cord-015369-72cjogxz 3217 14 22.2 22.2 CD cord-015369-72cjogxz 3217 15 % % NN cord-015369-72cjogxz 3217 16 ) ) -RRB- cord-015369-72cjogxz 3217 17 and and CC cord-015369-72cjogxz 3217 18 the the DT cord-015369-72cjogxz 3217 19 incidence incidence NN cord-015369-72cjogxz 3217 20 of of IN cord-015369-72cjogxz 3217 21 anal anal JJ cord-015369-72cjogxz 3217 22 stricture stricture NN cord-015369-72cjogxz 3217 23 lower low JJR cord-015369-72cjogxz 3217 24 than than IN cord-015369-72cjogxz 3217 25 in in IN cord-015369-72cjogxz 3217 26 the the DT cord-015369-72cjogxz 3217 27 open open JJ cord-015369-72cjogxz 3217 28 hemorrhoidectomy hemorrhoidectomy NN cord-015369-72cjogxz 3217 29 group group NN cord-015369-72cjogxz 3217 30 ( ( -LRB- cord-015369-72cjogxz 3217 31 5.5 5.5 CD cord-015369-72cjogxz 3217 32 % % NN cord-015369-72cjogxz 3217 33 vs. vs. IN cord-015369-72cjogxz 3217 34 25 25 CD cord-015369-72cjogxz 3217 35 % % NN cord-015369-72cjogxz 3217 36 ) ) -RRB- cord-015369-72cjogxz 3217 37 . . . cord-015369-72cjogxz 3218 1 Conclusions conclusion NNS cord-015369-72cjogxz 3218 2 . . . cord-015369-72cjogxz 3219 1 Grade grade NN cord-015369-72cjogxz 3219 2 - - HYPH cord-015369-72cjogxz 3219 3 dependent dependent JJ cord-015369-72cjogxz 3219 4 treatment treatment NN cord-015369-72cjogxz 3219 5 of of IN cord-015369-72cjogxz 3219 6 hemorrhoidal hemorrhoidal JJ cord-015369-72cjogxz 3219 7 disease disease NN cord-015369-72cjogxz 3219 8 with with IN cord-015369-72cjogxz 3219 9 respect respect NN cord-015369-72cjogxz 3219 10 to to IN cord-015369-72cjogxz 3219 11 the the DT cord-015369-72cjogxz 3219 12 clinical clinical JJ cord-015369-72cjogxz 3219 13 appearance appearance NN cord-015369-72cjogxz 3219 14 and and CC cord-015369-72cjogxz 3219 15 the the DT cord-015369-72cjogxz 3219 16 extent extent NN cord-015369-72cjogxz 3219 17 of of IN cord-015369-72cjogxz 3219 18 prolapse prolapse NN cord-015369-72cjogxz 3219 19 should should MD cord-015369-72cjogxz 3219 20 be be VB cord-015369-72cjogxz 3219 21 standard standard JJ cord-015369-72cjogxz 3219 22 today today NN cord-015369-72cjogxz 3219 23 . . . cord-015369-72cjogxz 3220 1 Stapled stapled JJ cord-015369-72cjogxz 3220 2 hemorrhoidopexy hemorrhoidopexy NNP cord-015369-72cjogxz 3220 3 appears appear VBZ cord-015369-72cjogxz 3220 4 to to TO cord-015369-72cjogxz 3220 5 be be VB cord-015369-72cjogxz 3220 6 an an DT cord-015369-72cjogxz 3220 7 intervention intervention NN cord-015369-72cjogxz 3220 8 with with IN cord-015369-72cjogxz 3220 9 less less RBR cord-015369-72cjogxz 3220 10 postoperative postoperative JJ cord-015369-72cjogxz 3220 11 pain pain NN cord-015369-72cjogxz 3220 12 and and CC cord-015369-72cjogxz 3220 13 faster fast JJR cord-015369-72cjogxz 3220 14 recovery recovery NN cord-015369-72cjogxz 3220 15 than than IN cord-015369-72cjogxz 3220 16 open open JJ cord-015369-72cjogxz 3220 17 hemorrhoidectomy hemorrhoidectomy NN cord-015369-72cjogxz 3220 18 , , , cord-015369-72cjogxz 3220 19 but but CC cord-015369-72cjogxz 3220 20 long long JJ cord-015369-72cjogxz 3220 21 - - HYPH cord-015369-72cjogxz 3220 22 term term NN cord-015369-72cjogxz 3220 23 results result NNS cord-015369-72cjogxz 3220 24 include include VBP cord-015369-72cjogxz 3220 25 a a DT cord-015369-72cjogxz 3220 26 higher high JJR cord-015369-72cjogxz 3220 27 recurrence recurrence NN cord-015369-72cjogxz 3220 28 rate rate NN cord-015369-72cjogxz 3220 29 and and CC cord-015369-72cjogxz 3220 30 a a DT cord-015369-72cjogxz 3220 31 higher high JJR cord-015369-72cjogxz 3220 32 incidence incidence NN cord-015369-72cjogxz 3220 33 of of IN cord-015369-72cjogxz 3220 34 fecal fecal JJ cord-015369-72cjogxz 3220 35 urgency urgency NN cord-015369-72cjogxz 3220 36 and and CC cord-015369-72cjogxz 3220 37 fecal fecal JJ cord-015369-72cjogxz 3220 38 incontinence incontinence NN cord-015369-72cjogxz 3220 39 . . . cord-015369-72cjogxz 3221 1 Background background NN cord-015369-72cjogxz 3221 2 . . . cord-015369-72cjogxz 3222 1 Anal anal JJ cord-015369-72cjogxz 3222 2 sepsis sepsis NN cord-015369-72cjogxz 3222 3 of of IN cord-015369-72cjogxz 3222 4 cryptoglandular cryptoglandular JJ cord-015369-72cjogxz 3222 5 origin origin NN cord-015369-72cjogxz 3222 6 might may MD cord-015369-72cjogxz 3222 7 be be VB cord-015369-72cjogxz 3222 8 challenging challenging JJ cord-015369-72cjogxz 3222 9 for for IN cord-015369-72cjogxz 3222 10 patients patient NNS cord-015369-72cjogxz 3222 11 and and CC cord-015369-72cjogxz 3222 12 surgeons surgeon NNS cord-015369-72cjogxz 3222 13 due due JJ cord-015369-72cjogxz 3222 14 to to IN cord-015369-72cjogxz 3222 15 recurrences recurrence NNS cord-015369-72cjogxz 3222 16 and and CC cord-015369-72cjogxz 3222 17 postoperative postoperative JJ cord-015369-72cjogxz 3222 18 fecal fecal JJ cord-015369-72cjogxz 3222 19 incontinence incontinence NN cord-015369-72cjogxz 3222 20 . . . cord-015369-72cjogxz 3223 1 Methods method NNS cord-015369-72cjogxz 3223 2 . . . cord-015369-72cjogxz 3224 1 Patients patient NNS cord-015369-72cjogxz 3224 2 with with IN cord-015369-72cjogxz 3224 3 anal anal JJ cord-015369-72cjogxz 3224 4 sepsis sepsis NN cord-015369-72cjogxz 3224 5 operated operate VBN cord-015369-72cjogxz 3224 6 on on IN cord-015369-72cjogxz 3224 7 between between IN cord-015369-72cjogxz 3224 8 January January NNP cord-015369-72cjogxz 3224 9 1st 1st NN cord-015369-72cjogxz 3224 10 1994 1994 CD cord-015369-72cjogxz 3224 11 and and CC cord-015369-72cjogxz 3224 12 December December NNP cord-015369-72cjogxz 3224 13 31st 31st NN cord-015369-72cjogxz 3224 14 2000 2000 CD cord-015369-72cjogxz 3224 15 at at IN cord-015369-72cjogxz 3224 16 the the DT cord-015369-72cjogxz 3224 17 Department Department NNP cord-015369-72cjogxz 3224 18 of of IN cord-015369-72cjogxz 3224 19 General General NNP cord-015369-72cjogxz 3224 20 Surgery Surgery NNP cord-015369-72cjogxz 3224 21 , , , cord-015369-72cjogxz 3224 22 Medical Medical NNP cord-015369-72cjogxz 3224 23 University University NNP cord-015369-72cjogxz 3224 24 Vienna Vienna NNP cord-015369-72cjogxz 3224 25 were be VBD cord-015369-72cjogxz 3224 26 retrospectively retrospectively RB cord-015369-72cjogxz 3224 27 analyzed analyze VBN cord-015369-72cjogxz 3224 28 in in IN cord-015369-72cjogxz 3224 29 terms term NNS cord-015369-72cjogxz 3224 30 of of IN cord-015369-72cjogxz 3224 31 recurrence recurrence NN cord-015369-72cjogxz 3224 32 and and CC cord-015369-72cjogxz 3224 33 postoperative postoperative JJ cord-015369-72cjogxz 3224 34 fecal fecal JJ cord-015369-72cjogxz 3224 35 incontinence incontinence NN cord-015369-72cjogxz 3224 36 by by IN cord-015369-72cjogxz 3224 37 chart chart NN cord-015369-72cjogxz 3224 38 review review NN cord-015369-72cjogxz 3224 39 and and CC cord-015369-72cjogxz 3224 40 by by IN cord-015369-72cjogxz 3224 41 telephone telephone NN cord-015369-72cjogxz 3224 42 interview interview NN cord-015369-72cjogxz 3224 43 using use VBG cord-015369-72cjogxz 3224 44 the the DT cord-015369-72cjogxz 3224 45 Vaizey Vaizey NNP cord-015369-72cjogxz 3224 46 incontinence incontinence NN cord-015369-72cjogxz 3224 47 score score NN cord-015369-72cjogxz 3224 48 . . . cord-015369-72cjogxz 3225 1 Results result NNS cord-015369-72cjogxz 3225 2 . . . cord-015369-72cjogxz 3226 1 Operative operative JJ cord-015369-72cjogxz 3226 2 treatment treatment NN cord-015369-72cjogxz 3226 3 was be VBD cord-015369-72cjogxz 3226 4 given give VBN cord-015369-72cjogxz 3226 5 to to IN cord-015369-72cjogxz 3226 6 222 222 CD cord-015369-72cjogxz 3226 7 male male NN cord-015369-72cjogxz 3226 8 and and CC cord-015369-72cjogxz 3226 9 78 78 CD cord-015369-72cjogxz 3226 10 female female JJ cord-015369-72cjogxz 3226 11 individuals individual NNS cord-015369-72cjogxz 3226 12 ( ( -LRB- cord-015369-72cjogxz 3226 13 74 74 CD cord-015369-72cjogxz 3226 14 % % NN cord-015369-72cjogxz 3226 15 vs. vs. IN cord-015369-72cjogxz 3226 16 26 26 CD cord-015369-72cjogxz 3226 17 % % NN cord-015369-72cjogxz 3226 18 ) ) -RRB- cord-015369-72cjogxz 3226 19 with with IN cord-015369-72cjogxz 3226 20 a a DT cord-015369-72cjogxz 3226 21 median median JJ cord-015369-72cjogxz 3226 22 age age NN cord-015369-72cjogxz 3226 23 of of IN cord-015369-72cjogxz 3226 24 40 40 CD cord-015369-72cjogxz 3226 25 years year NNS cord-015369-72cjogxz 3226 26 ( ( -LRB- cord-015369-72cjogxz 3226 27 20 20 CD cord-015369-72cjogxz 3226 28 - - SYM cord-015369-72cjogxz 3226 29 83 83 CD cord-015369-72cjogxz 3226 30 ) ) -RRB- cord-015369-72cjogxz 3226 31 . . . cord-015369-72cjogxz 3227 1 173 173 CD cord-015369-72cjogxz 3227 2 patients patient NNS cord-015369-72cjogxz 3227 3 were be VBD cord-015369-72cjogxz 3227 4 availabe availabe NN cord-015369-72cjogxz 3227 5 for for IN cord-015369-72cjogxz 3227 6 follow follow VB cord-015369-72cjogxz 3227 7 - - HYPH cord-015369-72cjogxz 3227 8 up up RP cord-015369-72cjogxz 3227 9 investigation investigation NN cord-015369-72cjogxz 3227 10 . . . cord-015369-72cjogxz 3228 1 After after IN cord-015369-72cjogxz 3228 2 a a DT cord-015369-72cjogxz 3228 3 median median NN cord-015369-72cjogxz 3228 4 of of IN cord-015369-72cjogxz 3228 5 121 121 CD cord-015369-72cjogxz 3228 6 months month NNS cord-015369-72cjogxz 3228 7 , , , cord-015369-72cjogxz 3228 8 55 55 CD cord-015369-72cjogxz 3228 9 patients patient NNS cord-015369-72cjogxz 3228 10 ( ( -LRB- cord-015369-72cjogxz 3228 11 32 32 CD cord-015369-72cjogxz 3228 12 % % NN cord-015369-72cjogxz 3228 13 ) ) -RRB- cord-015369-72cjogxz 3228 14 had have VBD cord-015369-72cjogxz 3228 15 no no DT cord-015369-72cjogxz 3228 16 recurrence recurrence NN cord-015369-72cjogxz 3228 17 after after IN cord-015369-72cjogxz 3228 18 a a DT cord-015369-72cjogxz 3228 19 single single JJ cord-015369-72cjogxz 3228 20 surgical surgical JJ cord-015369-72cjogxz 3228 21 procedure procedure NN cord-015369-72cjogxz 3228 22 . . . cord-015369-72cjogxz 3229 1 A a DT cord-015369-72cjogxz 3229 2 median median NN cord-015369-72cjogxz 3229 3 of of IN cord-015369-72cjogxz 3229 4 3 3 CD cord-015369-72cjogxz 3229 5 operations operation NNS cord-015369-72cjogxz 3229 6 ( ( -LRB- cord-015369-72cjogxz 3229 7 2 2 CD cord-015369-72cjogxz 3229 8 - - SYM cord-015369-72cjogxz 3229 9 19 19 CD cord-015369-72cjogxz 3229 10 ) ) -RRB- cord-015369-72cjogxz 3229 11 was be VBD cord-015369-72cjogxz 3229 12 performed perform VBN cord-015369-72cjogxz 3229 13 in in IN cord-015369-72cjogxz 3229 14 118 118 CD cord-015369-72cjogxz 3229 15 patients patient NNS cord-015369-72cjogxz 3229 16 with with IN cord-015369-72cjogxz 3229 17 multiple multiple JJ cord-015369-72cjogxz 3229 18 procedures procedure NNS cord-015369-72cjogxz 3229 19 . . . cord-015369-72cjogxz 3230 1 In in IN cord-015369-72cjogxz 3230 2 264 264 CD cord-015369-72cjogxz 3230 3 patients patient NNS cord-015369-72cjogxz 3230 4 ( ( -LRB- cord-015369-72cjogxz 3230 5 88 88 CD cord-015369-72cjogxz 3230 6 % % NN cord-015369-72cjogxz 3230 7 ) ) -RRB- cord-015369-72cjogxz 3230 8 , , , cord-015369-72cjogxz 3230 9 a a DT cord-015369-72cjogxz 3230 10 fistula fistula NN cord-015369-72cjogxz 3230 11 - - HYPH cord-015369-72cjogxz 3230 12 in in IN cord-015369-72cjogxz 3230 13 - - HYPH cord-015369-72cjogxz 3230 14 ano ano NNP cord-015369-72cjogxz 3230 15 was be VBD cord-015369-72cjogxz 3230 16 detected detect VBN cord-015369-72cjogxz 3230 17 . . . cord-015369-72cjogxz 3231 1 Vaizey Vaizey NNP cord-015369-72cjogxz 3231 2 score score NN cord-015369-72cjogxz 3231 3 was be VBD cord-015369-72cjogxz 3231 4 0 0 CD cord-015369-72cjogxz 3231 5 in in IN cord-015369-72cjogxz 3231 6 patients patient NNS cord-015369-72cjogxz 3231 7 with with IN cord-015369-72cjogxz 3231 8 single single JJ cord-015369-72cjogxz 3231 9 I i NN cord-015369-72cjogxz 3231 10 þ þ NN cord-015369-72cjogxz 3231 11 D d NN cord-015369-72cjogxz 3231 12 procedure procedure NN cord-015369-72cjogxz 3231 13 . . . cord-015369-72cjogxz 3232 1 In in IN cord-015369-72cjogxz 3232 2 patients patient NNS cord-015369-72cjogxz 3232 3 with with IN cord-015369-72cjogxz 3232 4 single single JJ cord-015369-72cjogxz 3232 5 I i NN cord-015369-72cjogxz 3232 6 þ þ NN cord-015369-72cjogxz 3232 7 D D NNP cord-015369-72cjogxz 3232 8 plus plus CC cord-015369-72cjogxz 3232 9 fistulotomy fistulotomy NN cord-015369-72cjogxz 3232 10 , , , cord-015369-72cjogxz 3232 11 mild mild JJ cord-015369-72cjogxz 3232 12 incontinence incontinence NN cord-015369-72cjogxz 3232 13 was be VBD cord-015369-72cjogxz 3232 14 seen see VBN cord-015369-72cjogxz 3232 15 in in IN cord-015369-72cjogxz 3232 16 9 9 CD cord-015369-72cjogxz 3232 17 % % NN cord-015369-72cjogxz 3232 18 and and CC cord-015369-72cjogxz 3232 19 severe severe JJ cord-015369-72cjogxz 3232 20 incontinence incontinence NN cord-015369-72cjogxz 3232 21 in in IN cord-015369-72cjogxz 3232 22 4 4 CD cord-015369-72cjogxz 3232 23 % % NN cord-015369-72cjogxz 3232 24 . . . cord-015369-72cjogxz 3233 1 In in IN cord-015369-72cjogxz 3233 2 patients patient NNS cord-015369-72cjogxz 3233 3 with with IN cord-015369-72cjogxz 3233 4 muliple muliple JJ cord-015369-72cjogxz 3233 5 procedures procedure NNS cord-015369-72cjogxz 3233 6 , , , cord-015369-72cjogxz 3233 7 mild mild JJ cord-015369-72cjogxz 3233 8 fecal fecal JJ cord-015369-72cjogxz 3233 9 disturbances disturbance NNS cord-015369-72cjogxz 3233 10 were be VBD cord-015369-72cjogxz 3233 11 assessed assess VBN cord-015369-72cjogxz 3233 12 in in IN cord-015369-72cjogxz 3233 13 19 19 CD cord-015369-72cjogxz 3233 14 % % NN cord-015369-72cjogxz 3233 15 and and CC cord-015369-72cjogxz 3233 16 severe severe JJ cord-015369-72cjogxz 3233 17 disturbances disturbance NNS cord-015369-72cjogxz 3233 18 in in IN cord-015369-72cjogxz 3233 19 4 4 CD cord-015369-72cjogxz 3233 20 % % NN cord-015369-72cjogxz 3233 21 . . . cord-015369-72cjogxz 3234 1 Conclusions conclusion NNS cord-015369-72cjogxz 3234 2 . . . cord-015369-72cjogxz 3235 1 Treatment treatment NN cord-015369-72cjogxz 3235 2 of of IN cord-015369-72cjogxz 3235 3 anal anal JJ cord-015369-72cjogxz 3235 4 sepsis sepsis NN cord-015369-72cjogxz 3235 5 and and CC cord-015369-72cjogxz 3235 6 fistula fistula NN cord-015369-72cjogxz 3235 7 - - HYPH cord-015369-72cjogxz 3235 8 in in IN cord-015369-72cjogxz 3235 9 - - HYPH cord-015369-72cjogxz 3235 10 ano ano NNP cord-015369-72cjogxz 3235 11 is be VBZ cord-015369-72cjogxz 3235 12 associated associate VBN cord-015369-72cjogxz 3235 13 with with IN cord-015369-72cjogxz 3235 14 a a DT cord-015369-72cjogxz 3235 15 high high JJ cord-015369-72cjogxz 3235 16 recurrence recurrence NN cord-015369-72cjogxz 3235 17 rate rate NN cord-015369-72cjogxz 3235 18 and and CC cord-015369-72cjogxz 3235 19 a a DT cord-015369-72cjogxz 3235 20 substantial substantial JJ cord-015369-72cjogxz 3235 21 risk risk NN cord-015369-72cjogxz 3235 22 of of IN cord-015369-72cjogxz 3235 23 fecal fecal JJ cord-015369-72cjogxz 3235 24 incontinence incontinence NN cord-015369-72cjogxz 3235 25 in in IN cord-015369-72cjogxz 3235 26 this this DT cord-015369-72cjogxz 3235 27 analysis analysis NN cord-015369-72cjogxz 3235 28 . . . cord-015369-72cjogxz 3236 1 Data datum NNS cord-015369-72cjogxz 3236 2 suggest suggest VBP cord-015369-72cjogxz 3236 3 that that IN cord-015369-72cjogxz 3236 4 a a DT cord-015369-72cjogxz 3236 5 search search NN cord-015369-72cjogxz 3236 6 for for IN cord-015369-72cjogxz 3236 7 a a DT cord-015369-72cjogxz 3236 8 fistula fistula NN cord-015369-72cjogxz 3236 9 - - HYPH cord-015369-72cjogxz 3236 10 in in IN cord-015369-72cjogxz 3236 11 - - HYPH cord-015369-72cjogxz 3236 12 ano ano NNP cord-015369-72cjogxz 3236 13 should should MD cord-015369-72cjogxz 3236 14 be be VB cord-015369-72cjogxz 3236 15 performed perform VBN cord-015369-72cjogxz 3236 16 already already RB cord-015369-72cjogxz 3236 17 at at IN cord-015369-72cjogxz 3236 18 the the DT cord-015369-72cjogxz 3236 19 primary primary JJ cord-015369-72cjogxz 3236 20 operation operation NN cord-015369-72cjogxz 3236 21 . . . cord-015369-72cjogxz 3237 1 In in IN cord-015369-72cjogxz 3237 2 a a DT cord-015369-72cjogxz 3237 3 case case NN cord-015369-72cjogxz 3237 4 of of IN cord-015369-72cjogxz 3237 5 recurrence recurrence NN cord-015369-72cjogxz 3237 6 , , , cord-015369-72cjogxz 3237 7 high high JJ cord-015369-72cjogxz 3237 8 transsphincteric transsphincteric NNP cord-015369-72cjogxz 3237 9 , , , cord-015369-72cjogxz 3237 10 suprasphincteric suprasphincteric JJ cord-015369-72cjogxz 3237 11 or or CC cord-015369-72cjogxz 3237 12 complex complex JJ cord-015369-72cjogxz 3237 13 fistula fistula NN cord-015369-72cjogxz 3237 14 - - HYPH cord-015369-72cjogxz 3237 15 in in IN cord-015369-72cjogxz 3237 16 - - HYPH cord-015369-72cjogxz 3237 17 ano ano NNP cord-015369-72cjogxz 3237 18 a a DT cord-015369-72cjogxz 3237 19 specialized specialized JJ cord-015369-72cjogxz 3237 20 coloproctologist coloproctologist NN cord-015369-72cjogxz 3237 21 should should MD cord-015369-72cjogxz 3237 22 be be VB cord-015369-72cjogxz 3237 23 involved involve VBN cord-015369-72cjogxz 3237 24 to to TO cord-015369-72cjogxz 3237 25 avoid avoid VB cord-015369-72cjogxz 3237 26 damage damage NN cord-015369-72cjogxz 3237 27 to to IN cord-015369-72cjogxz 3237 28 the the DT cord-015369-72cjogxz 3237 29 anal anal JJ cord-015369-72cjogxz 3237 30 sphincter sphincter NN cord-015369-72cjogxz 3237 31 muscle muscle NN cord-015369-72cjogxz 3237 32 . . . cord-015369-72cjogxz 3238 1 Die die VB cord-015369-72cjogxz 3238 2 hohe hohe NNP cord-015369-72cjogxz 3238 3 und und IN cord-015369-72cjogxz 3238 4 rezidivierende rezidivierende NNP cord-015369-72cjogxz 3238 5 Analfistel Analfistel NNP cord-015369-72cjogxz 3238 6 Background Background NNP cord-015369-72cjogxz 3238 7 . . . cord-015369-72cjogxz 3239 1 Studies study NNS cord-015369-72cjogxz 3239 2 have have VBP cord-015369-72cjogxz 3239 3 reported report VBN cord-015369-72cjogxz 3239 4 excellent excellent JJ cord-015369-72cjogxz 3239 5 healing healing NN cord-015369-72cjogxz 3239 6 rates rate NNS cord-015369-72cjogxz 3239 7 for for IN cord-015369-72cjogxz 3239 8 the the DT cord-015369-72cjogxz 3239 9 treatment treatment NN cord-015369-72cjogxz 3239 10 of of IN cord-015369-72cjogxz 3239 11 CPS cp NNS cord-015369-72cjogxz 3239 12 with with IN cord-015369-72cjogxz 3239 13 different different JJ cord-015369-72cjogxz 3239 14 skin skin NN cord-015369-72cjogxz 3239 15 flaps flap NNS cord-015369-72cjogxz 3239 16 . . . cord-015369-72cjogxz 3240 1 The the DT cord-015369-72cjogxz 3240 2 cosmetic cosmetic JJ cord-015369-72cjogxz 3240 3 outcome outcome NN cord-015369-72cjogxz 3240 4 is be VBZ cord-015369-72cjogxz 3240 5 less less RBR cord-015369-72cjogxz 3240 6 investigated investigate VBN cord-015369-72cjogxz 3240 7 . . . cord-015369-72cjogxz 3241 1 The the DT cord-015369-72cjogxz 3241 2 aim aim NN cord-015369-72cjogxz 3241 3 was be VBD cord-015369-72cjogxz 3241 4 to to TO cord-015369-72cjogxz 3241 5 enlighten enlighten VB cord-015369-72cjogxz 3241 6 the the DT cord-015369-72cjogxz 3241 7 body body NN cord-015369-72cjogxz 3241 8 image image NN cord-015369-72cjogxz 3241 9 changes change NNS cord-015369-72cjogxz 3241 10 and and CC cord-015369-72cjogxz 3241 11 patients patient NNS cord-015369-72cjogxz 3241 12 satisfaction satisfaction NN cord-015369-72cjogxz 3241 13 after after IN cord-015369-72cjogxz 3241 14 Limberg Limberg NNP cord-015369-72cjogxz 3241 15 flap flap NN cord-015369-72cjogxz 3241 16 . . . cord-015369-72cjogxz 3242 1 Methods method NNS cord-015369-72cjogxz 3242 2 . . . cord-015369-72cjogxz 3243 1 From from IN cord-015369-72cjogxz 3243 2 August August NNP cord-015369-72cjogxz 3243 3 2006 2006 CD cord-015369-72cjogxz 3243 4 to to IN cord-015369-72cjogxz 3243 5 December December NNP cord-015369-72cjogxz 3243 6 2007 2007 CD cord-015369-72cjogxz 3243 7 72 72 CD cord-015369-72cjogxz 3243 8 consecutive consecutive JJ cord-015369-72cjogxz 3243 9 patients patient NNS cord-015369-72cjogxz 3243 10 , , , cord-015369-72cjogxz 3243 11 mean mean VB cord-015369-72cjogxz 3243 12 age age NN cord-015369-72cjogxz 3243 13 of of IN cord-015369-72cjogxz 3243 14 26.5 26.5 CD cord-015369-72cjogxz 3243 15 years year NNS cord-015369-72cjogxz 3243 16 ( ( -LRB- cord-015369-72cjogxz 3243 17 AE8.6 AE8.6 NNP cord-015369-72cjogxz 3243 18 ) ) -RRB- cord-015369-72cjogxz 3243 19 with with IN cord-015369-72cjogxz 3243 20 CPS cp NNS cord-015369-72cjogxz 3243 21 underwent undergo VBD cord-015369-72cjogxz 3243 22 excision excision NN cord-015369-72cjogxz 3243 23 and and CC cord-015369-72cjogxz 3243 24 closure closure NN cord-015369-72cjogxz 3243 25 with with IN cord-015369-72cjogxz 3243 26 Limberg Limberg NNP cord-015369-72cjogxz 3243 27 flap flap NN cord-015369-72cjogxz 3243 28 . . . cord-015369-72cjogxz 3244 1 At at IN cord-015369-72cjogxz 3244 2 30 30 CD cord-015369-72cjogxz 3244 3 days day NNS cord-015369-72cjogxz 3244 4 morbidity morbidity NN cord-015369-72cjogxz 3244 5 and and CC cord-015369-72cjogxz 3244 6 time time NN cord-015369-72cjogxz 3244 7 off off RP cord-015369-72cjogxz 3244 8 work work NN cord-015369-72cjogxz 3244 9 were be VBD cord-015369-72cjogxz 3244 10 accessed access VBN cord-015369-72cjogxz 3244 11 . . . cord-015369-72cjogxz 3245 1 Late late JJ cord-015369-72cjogxz 3245 2 infection infection NN cord-015369-72cjogxz 3245 3 , , , cord-015369-72cjogxz 3245 4 recurrence recurrence NN cord-015369-72cjogxz 3245 5 rate rate NN cord-015369-72cjogxz 3245 6 , , , cord-015369-72cjogxz 3245 7 selfesteem selfesteem NNP cord-015369-72cjogxz 3245 8 ( ( -LRB- cord-015369-72cjogxz 3245 9 worst bad JJS cord-015369-72cjogxz 3245 10 1 1 CD cord-015369-72cjogxz 3245 11 , , , cord-015369-72cjogxz 3245 12 best good JJS cord-015369-72cjogxz 3245 13 10 10 CD cord-015369-72cjogxz 3245 14 ) ) -RRB- cord-015369-72cjogxz 3245 15 , , , cord-015369-72cjogxz 3245 16 cosmesis cosmesis NNP cord-015369-72cjogxz 3245 17 ( ( -LRB- cord-015369-72cjogxz 3245 18 3 3 CD cord-015369-72cjogxz 3245 19 , , , cord-015369-72cjogxz 3245 20 24 24 CD cord-015369-72cjogxz 3245 21 ) ) -RRB- cord-015369-72cjogxz 3245 22 , , , cord-015369-72cjogxz 3245 23 body body NN cord-015369-72cjogxz 3245 24 image image NN cord-015369-72cjogxz 3245 25 ( ( -LRB- cord-015369-72cjogxz 3245 26 5 5 CD cord-015369-72cjogxz 3245 27 , , , cord-015369-72cjogxz 3245 28 20 20 CD cord-015369-72cjogxz 3245 29 ) ) -RRB- cord-015369-72cjogxz 3245 30 , , , cord-015369-72cjogxz 3245 31 and and CC cord-015369-72cjogxz 3245 32 patients patient NNS cord-015369-72cjogxz 3245 33 satisfaction satisfaction NN cord-015369-72cjogxz 3245 34 ( ( -LRB- cord-015369-72cjogxz 3245 35 0 0 CD cord-015369-72cjogxz 3245 36 , , , cord-015369-72cjogxz 3245 37 10 10 CD cord-015369-72cjogxz 3245 38 ) ) -RRB- cord-015369-72cjogxz 3245 39 at at IN cord-015369-72cjogxz 3245 40 one one CD cord-015369-72cjogxz 3245 41 year year NN cord-015369-72cjogxz 3245 42 were be VBD cord-015369-72cjogxz 3245 43 analyzed analyze VBN cord-015369-72cjogxz 3245 44 prospectively prospectively RB cord-015369-72cjogxz 3245 45 . . . cord-015369-72cjogxz 3246 1 Results result NNS cord-015369-72cjogxz 3246 2 . . . cord-015369-72cjogxz 3247 1 No no DT cord-015369-72cjogxz 3247 2 major major JJ cord-015369-72cjogxz 3247 3 complications complication NNS cord-015369-72cjogxz 3247 4 such such JJ cord-015369-72cjogxz 3247 5 as as IN cord-015369-72cjogxz 3247 6 flap flap NN cord-015369-72cjogxz 3247 7 necrosis necrosis NN cord-015369-72cjogxz 3247 8 occurred occur VBD cord-015369-72cjogxz 3247 9 . . . cord-015369-72cjogxz 3248 1 Minor minor JJ cord-015369-72cjogxz 3248 2 complications complication NNS cord-015369-72cjogxz 3248 3 occurred occur VBD cord-015369-72cjogxz 3248 4 in in IN cord-015369-72cjogxz 3248 5 19 19 CD cord-015369-72cjogxz 3248 6 % % NN cord-015369-72cjogxz 3248 7 , , , cord-015369-72cjogxz 3248 8 including include VBG cord-015369-72cjogxz 3248 9 superficial superficial JJ cord-015369-72cjogxz 3248 10 infection infection NN cord-015369-72cjogxz 3248 11 and and CC cord-015369-72cjogxz 3248 12 partial partial JJ cord-015369-72cjogxz 3248 13 suture suture NN cord-015369-72cjogxz 3248 14 dehiscence dehiscence NN cord-015369-72cjogxz 3248 15 . . . cord-015369-72cjogxz 3249 1 Mean mean JJ cord-015369-72cjogxz 3249 2 time time NN cord-015369-72cjogxz 3249 3 off off IN cord-015369-72cjogxz 3249 4 work work NN cord-015369-72cjogxz 3249 5 was be VBD cord-015369-72cjogxz 3249 6 24.1 24.1 CD cord-015369-72cjogxz 3249 7 days day NNS cord-015369-72cjogxz 3249 8 ( ( -LRB- cord-015369-72cjogxz 3249 9 AE18.8 AE18.8 NNP cord-015369-72cjogxz 3249 10 ) ) -RRB- cord-015369-72cjogxz 3249 11 . . . cord-015369-72cjogxz 3250 1 In in IN cord-015369-72cjogxz 3250 2 5 5 CD cord-015369-72cjogxz 3250 3 patients patient NNS cord-015369-72cjogxz 3250 4 ( ( -LRB- cord-015369-72cjogxz 3250 5 7 7 CD cord-015369-72cjogxz 3250 6 % % NN cord-015369-72cjogxz 3250 7 ) ) -RRB- cord-015369-72cjogxz 3250 8 occurred occur VBD cord-015369-72cjogxz 3250 9 a a DT cord-015369-72cjogxz 3250 10 late late JJ cord-015369-72cjogxz 3250 11 local local JJ cord-015369-72cjogxz 3250 12 infection infection NN cord-015369-72cjogxz 3250 13 in in IN cord-015369-72cjogxz 3250 14 the the DT cord-015369-72cjogxz 3250 15 first first JJ cord-015369-72cjogxz 3250 16 12 12 CD cord-015369-72cjogxz 3250 17 months month NNS cord-015369-72cjogxz 3250 18 . . . cord-015369-72cjogxz 3251 1 The the DT cord-015369-72cjogxz 3251 2 recurrence recurrence NN cord-015369-72cjogxz 3251 3 rate rate NN cord-015369-72cjogxz 3251 4 was be VBD cord-015369-72cjogxz 3251 5 2.8 2.8 CD cord-015369-72cjogxz 3251 6 % % NN cord-015369-72cjogxz 3251 7 after after IN cord-015369-72cjogxz 3251 8 one one CD cord-015369-72cjogxz 3251 9 year year NN cord-015369-72cjogxz 3251 10 . . . cord-015369-72cjogxz 3252 1 Self self NN cord-015369-72cjogxz 3252 2 - - HYPH cord-015369-72cjogxz 3252 3 esteem esteem NN cord-015369-72cjogxz 3252 4 before before IN cord-015369-72cjogxz 3252 5 and and CC cord-015369-72cjogxz 3252 6 after after IN cord-015369-72cjogxz 3252 7 the the DT cord-015369-72cjogxz 3252 8 operation operation NN cord-015369-72cjogxz 3252 9 remained remain VBD cord-015369-72cjogxz 3252 10 almost almost RB cord-015369-72cjogxz 3252 11 unchanged unchanged JJ cord-015369-72cjogxz 3252 12 ( ( -LRB- cord-015369-72cjogxz 3252 13 before before IN cord-015369-72cjogxz 3252 14 8.0 8.0 CD cord-015369-72cjogxz 3252 15 , , , cord-015369-72cjogxz 3252 16 after after IN cord-015369-72cjogxz 3252 17 7.6 7.6 CD cord-015369-72cjogxz 3252 18 ) ) -RRB- cord-015369-72cjogxz 3252 19 ( ( -LRB- cord-015369-72cjogxz 3252 20 p p NN cord-015369-72cjogxz 3252 21 ¼ ¼ CD cord-015369-72cjogxz 3252 22 0.27 0.27 CD cord-015369-72cjogxz 3252 23 ) ) -RRB- cord-015369-72cjogxz 3252 24 . . . cord-015369-72cjogxz 3253 1 Mean mean JJ cord-015369-72cjogxz 3253 2 cosmesis cosmesis NN cord-015369-72cjogxz 3253 3 and and CC cord-015369-72cjogxz 3253 4 body body NN cord-015369-72cjogxz 3253 5 image image NN cord-015369-72cjogxz 3253 6 were be VBD cord-015369-72cjogxz 3253 7 acceptable acceptable JJ cord-015369-72cjogxz 3253 8 , , , cord-015369-72cjogxz 3253 9 16.5 16.5 CD cord-015369-72cjogxz 3253 10 ( ( -LRB- cord-015369-72cjogxz 3253 11 AE4.0 AE4.0 NNP cord-015369-72cjogxz 3253 12 ) ) -RRB- cord-015369-72cjogxz 3253 13 and and CC cord-015369-72cjogxz 3253 14 18.0 18.0 CD cord-015369-72cjogxz 3253 15 ( ( -LRB- cord-015369-72cjogxz 3253 16 AE2.6 AE2.6 NNP cord-015369-72cjogxz 3253 17 ) ) -RRB- cord-015369-72cjogxz 3253 18 respectively respectively RB cord-015369-72cjogxz 3253 19 . . . cord-015369-72cjogxz 3254 1 92 92 CD cord-015369-72cjogxz 3254 2 % % NN cord-015369-72cjogxz 3254 3 estimated estimate VBD cord-015369-72cjogxz 3254 4 their -PRON- PRP$ cord-015369-72cjogxz 3254 5 change change NN cord-015369-72cjogxz 3254 6 of of IN cord-015369-72cjogxz 3254 7 body body NN cord-015369-72cjogxz 3254 8 image image NN cord-015369-72cjogxz 3254 9 as as IN cord-015369-72cjogxz 3254 10 acceptable acceptable JJ cord-015369-72cjogxz 3254 11 ( ( -LRB- cord-015369-72cjogxz 3254 12 > > NFP cord-015369-72cjogxz 3254 13 14 14 CD cord-015369-72cjogxz 3254 14 ) ) -RRB- cord-015369-72cjogxz 3254 15 . . . cord-015369-72cjogxz 3255 1 76 76 CD cord-015369-72cjogxz 3255 2 % % NN cord-015369-72cjogxz 3255 3 of of IN cord-015369-72cjogxz 3255 4 the the DT cord-015369-72cjogxz 3255 5 patients patient NNS cord-015369-72cjogxz 3255 6 were be VBD cord-015369-72cjogxz 3255 7 highly highly RB cord-015369-72cjogxz 3255 8 satisfied satisfied JJ cord-015369-72cjogxz 3255 9 with with IN cord-015369-72cjogxz 3255 10 the the DT cord-015369-72cjogxz 3255 11 procedure procedure NN cord-015369-72cjogxz 3255 12 ( ( -LRB- cord-015369-72cjogxz 3255 13 > > NFP cord-015369-72cjogxz 3255 14 6 6 CD cord-015369-72cjogxz 3255 15 ) ) -RRB- cord-015369-72cjogxz 3255 16 and and CC cord-015369-72cjogxz 3255 17 mean mean VB cord-015369-72cjogxz 3255 18 patients patient NNS cord-015369-72cjogxz 3255 19 satisfaction satisfaction NN cord-015369-72cjogxz 3255 20 was be VBD cord-015369-72cjogxz 3255 21 7.5 7.5 CD cord-015369-72cjogxz 3255 22 ( ( -LRB- cord-015369-72cjogxz 3255 23 AE2.5 AE2.5 NNP cord-015369-72cjogxz 3255 24 ) ) -RRB- cord-015369-72cjogxz 3255 25 . . . cord-015369-72cjogxz 3256 1 Conclusions conclusion NNS cord-015369-72cjogxz 3256 2 . . . cord-015369-72cjogxz 3257 1 Morbidity morbidity NN cord-015369-72cjogxz 3257 2 and and CC cord-015369-72cjogxz 3257 3 recurrence recurrence NN cord-015369-72cjogxz 3257 4 rate rate NN cord-015369-72cjogxz 3257 5 after after IN cord-015369-72cjogxz 3257 6 treatment treatment NN cord-015369-72cjogxz 3257 7 with with IN cord-015369-72cjogxz 3257 8 Limberg Limberg NNP cord-015369-72cjogxz 3257 9 flap flap NN cord-015369-72cjogxz 3257 10 is be VBZ cord-015369-72cjogxz 3257 11 low low JJ cord-015369-72cjogxz 3257 12 and and CC cord-015369-72cjogxz 3257 13 compares compare VBZ cord-015369-72cjogxz 3257 14 favorably favorably RB cord-015369-72cjogxz 3257 15 to to IN cord-015369-72cjogxz 3257 16 other other JJ cord-015369-72cjogxz 3257 17 treatments treatment NNS cord-015369-72cjogxz 3257 18 . . . cord-015369-72cjogxz 3258 1 Change change NN cord-015369-72cjogxz 3258 2 of of IN cord-015369-72cjogxz 3258 3 body body NN cord-015369-72cjogxz 3258 4 image image NN cord-015369-72cjogxz 3258 5 and and CC cord-015369-72cjogxz 3258 6 cosmesis cosmesis NNP cord-015369-72cjogxz 3258 7 are be VBP cord-015369-72cjogxz 3258 8 acceptable acceptable JJ cord-015369-72cjogxz 3258 9 in in IN cord-015369-72cjogxz 3258 10 most most JJS cord-015369-72cjogxz 3258 11 patients patient NNS cord-015369-72cjogxz 3258 12 , , , cord-015369-72cjogxz 3258 13 but but CC cord-015369-72cjogxz 3258 14 are be VBP cord-015369-72cjogxz 3258 15 a a DT cord-015369-72cjogxz 3258 16 problem problem NN cord-015369-72cjogxz 3258 17 in in IN cord-015369-72cjogxz 3258 18 some some DT cord-015369-72cjogxz 3258 19 and and CC cord-015369-72cjogxz 3258 20 should should MD cord-015369-72cjogxz 3258 21 be be VB cord-015369-72cjogxz 3258 22 addressed address VBN cord-015369-72cjogxz 3258 23 preoperatively preoperatively RB cord-015369-72cjogxz 3258 24 . . . cord-015369-72cjogxz 3259 1 Background background NN cord-015369-72cjogxz 3259 2 . . . cord-015369-72cjogxz 3260 1 There there EX cord-015369-72cjogxz 3260 2 are be VBP cord-015369-72cjogxz 3260 3 more more JJR cord-015369-72cjogxz 3260 4 than than IN cord-015369-72cjogxz 3260 5 a a DT cord-015369-72cjogxz 3260 6 hundred hundred CD cord-015369-72cjogxz 3260 7 different different JJ cord-015369-72cjogxz 3260 8 techniques technique NNS cord-015369-72cjogxz 3260 9 to to TO cord-015369-72cjogxz 3260 10 operate operate VB cord-015369-72cjogxz 3260 11 on on IN cord-015369-72cjogxz 3260 12 a a DT cord-015369-72cjogxz 3260 13 rectal rectal JJ cord-015369-72cjogxz 3260 14 prolapse prolapse NN cord-015369-72cjogxz 3260 15 . . . cord-015369-72cjogxz 3261 1 For for IN cord-015369-72cjogxz 3261 2 old old JJ cord-015369-72cjogxz 3261 3 and and CC cord-015369-72cjogxz 3261 4 frail frail JJ cord-015369-72cjogxz 3261 5 patients patient NNS cord-015369-72cjogxz 3261 6 the the DT cord-015369-72cjogxz 3261 7 perineal perineal JJ cord-015369-72cjogxz 3261 8 approach approach NN cord-015369-72cjogxz 3261 9 is be VBZ cord-015369-72cjogxz 3261 10 preferred prefer VBN cord-015369-72cjogxz 3261 11 . . . cord-015369-72cjogxz 3262 1 The the DT cord-015369-72cjogxz 3262 2 Rehn Rehn NNP cord-015369-72cjogxz 3262 3 - - HYPH cord-015369-72cjogxz 3262 4 Delorme Delorme NNP cord-015369-72cjogxz 3262 5 procedure procedure NN cord-015369-72cjogxz 3262 6 and and CC cord-015369-72cjogxz 3262 7 the the DT cord-015369-72cjogxz 3262 8 Altemeier Altemeier NNP cord-015369-72cjogxz 3262 9 rectosigmoidektomy rectosigmoidektomy NN cord-015369-72cjogxz 3262 10 are be VBP cord-015369-72cjogxz 3262 11 currently currently RB cord-015369-72cjogxz 3262 12 the the DT cord-015369-72cjogxz 3262 13 most most RBS cord-015369-72cjogxz 3262 14 popular popular JJ cord-015369-72cjogxz 3262 15 perineal perineal JJ cord-015369-72cjogxz 3262 16 procedures procedure NNS cord-015369-72cjogxz 3262 17 . . . cord-015369-72cjogxz 3263 1 Both both DT cord-015369-72cjogxz 3263 2 are be VBP cord-015369-72cjogxz 3263 3 demanding demand VBG cord-015369-72cjogxz 3263 4 and and CC cord-015369-72cjogxz 3263 5 time time NN cord-015369-72cjogxz 3263 6 consuming consume VBG cord-015369-72cjogxz 3263 7 . . . cord-015369-72cjogxz 3264 1 The the DT cord-015369-72cjogxz 3264 2 aim aim NN cord-015369-72cjogxz 3264 3 was be VBD cord-015369-72cjogxz 3264 4 to to TO cord-015369-72cjogxz 3264 5 develop develop VB cord-015369-72cjogxz 3264 6 a a DT cord-015369-72cjogxz 3264 7 procedure procedure NN cord-015369-72cjogxz 3264 8 , , , cord-015369-72cjogxz 3264 9 which which WDT cord-015369-72cjogxz 3264 10 is be VBZ cord-015369-72cjogxz 3264 11 easy easy JJ cord-015369-72cjogxz 3264 12 and and CC cord-015369-72cjogxz 3264 13 fast fast JJ cord-015369-72cjogxz 3264 14 to to TO cord-015369-72cjogxz 3264 15 perform perform VB cord-015369-72cjogxz 3264 16 and and CC cord-015369-72cjogxz 3264 17 has have VBZ cord-015369-72cjogxz 3264 18 a a DT cord-015369-72cjogxz 3264 19 good good JJ cord-015369-72cjogxz 3264 20 outcome outcome NN cord-015369-72cjogxz 3264 21 . . . cord-015369-72cjogxz 3265 1 Methods method NNS cord-015369-72cjogxz 3265 2 . . . cord-015369-72cjogxz 3266 1 Internal internal JJ cord-015369-72cjogxz 3266 2 rectal rectal JJ cord-015369-72cjogxz 3266 3 redundancy redundancy NN cord-015369-72cjogxz 3266 4 has have VBZ cord-015369-72cjogxz 3266 5 recently recently RB cord-015369-72cjogxz 3266 6 been be VBN cord-015369-72cjogxz 3266 7 successfully successfully RB cord-015369-72cjogxz 3266 8 treated treat VBN cord-015369-72cjogxz 3266 9 with with IN cord-015369-72cjogxz 3266 10 transanal transanal JJ cord-015369-72cjogxz 3266 11 resection resection NN cord-015369-72cjogxz 3266 12 using use VBG cord-015369-72cjogxz 3266 13 the the DT cord-015369-72cjogxz 3266 14 Contour Contour NNP cord-015369-72cjogxz 3266 15 + + CC cord-015369-72cjogxz 3266 16 Transtar Transtar NNP cord-015369-72cjogxz 3266 17 TM TM NNP cord-015369-72cjogxz 3266 18 stapler stapler NN cord-015369-72cjogxz 3266 19 . . . cord-015369-72cjogxz 3267 1 This this DT cord-015369-72cjogxz 3267 2 technique technique NN cord-015369-72cjogxz 3267 3 has have VBZ cord-015369-72cjogxz 3267 4 been be VBN cord-015369-72cjogxz 3267 5 modified modify VBN cord-015369-72cjogxz 3267 6 to to IN cord-015369-72cjogxz 3267 7 the the DT cord-015369-72cjogxz 3267 8 perineal perineal JJ cord-015369-72cjogxz 3267 9 stapled staple VBN cord-015369-72cjogxz 3267 10 prolapse prolapse NN cord-015369-72cjogxz 3267 11 resection resection NN cord-015369-72cjogxz 3267 12 ( ( -LRB- cord-015369-72cjogxz 3267 13 PSP PSP NNP cord-015369-72cjogxz 3267 14 ) ) -RRB- cord-015369-72cjogxz 3267 15 . . . cord-015369-72cjogxz 3268 1 The the DT cord-015369-72cjogxz 3268 2 prolapse prolapse NN cord-015369-72cjogxz 3268 3 is be VBZ cord-015369-72cjogxz 3268 4 completely completely RB cord-015369-72cjogxz 3268 5 pulled pull VBN cord-015369-72cjogxz 3268 6 out out RP cord-015369-72cjogxz 3268 7 and and CC cord-015369-72cjogxz 3268 8 then then RB cord-015369-72cjogxz 3268 9 axially axially RB cord-015369-72cjogxz 3268 10 cut cut VBD cord-015369-72cjogxz 3268 11 open open JJ cord-015369-72cjogxz 3268 12 at at IN cord-015369-72cjogxz 3268 13 three three CD cord-015369-72cjogxz 3268 14 o'clock o'clock NN cord-015369-72cjogxz 3268 15 in in IN cord-015369-72cjogxz 3268 16 lithotomy lithotomy NN cord-015369-72cjogxz 3268 17 position position NN cord-015369-72cjogxz 3268 18 with with IN cord-015369-72cjogxz 3268 19 a a DT cord-015369-72cjogxz 3268 20 straight straight JJ cord-015369-72cjogxz 3268 21 stapler stapler NN cord-015369-72cjogxz 3268 22 . . . cord-015369-72cjogxz 3269 1 Thereafter thereafter RB cord-015369-72cjogxz 3269 2 the the DT cord-015369-72cjogxz 3269 3 prolapse prolapse NN cord-015369-72cjogxz 3269 4 is be VBZ cord-015369-72cjogxz 3269 5 stepwise stepwise RB cord-015369-72cjogxz 3269 6 resected resect VBN cord-015369-72cjogxz 3269 7 with with IN cord-015369-72cjogxz 3269 8 the the DT cord-015369-72cjogxz 3269 9 curved curved JJ cord-015369-72cjogxz 3269 10 Contour Contour NNP cord-015369-72cjogxz 3269 11 + + CC cord-015369-72cjogxz 3269 12 Transtar Transtar NNP cord-015369-72cjogxz 3269 13 TM TM NNP cord-015369-72cjogxz 3269 14 stapler stapler NN cord-015369-72cjogxz 3269 15 . . . cord-015369-72cjogxz 3270 1 At at IN cord-015369-72cjogxz 3270 2 the the DT cord-015369-72cjogxz 3270 3 end end NN cord-015369-72cjogxz 3270 4 of of IN cord-015369-72cjogxz 3270 5 the the DT cord-015369-72cjogxz 3270 6 circular circular JJ cord-015369-72cjogxz 3270 7 resection resection NN cord-015369-72cjogxz 3270 8 the the DT cord-015369-72cjogxz 3270 9 beginning beginning NN cord-015369-72cjogxz 3270 10 of of IN cord-015369-72cjogxz 3270 11 it -PRON- PRP cord-015369-72cjogxz 3270 12 is be VBZ cord-015369-72cjogxz 3270 13 reached reach VBN cord-015369-72cjogxz 3270 14 again again RB cord-015369-72cjogxz 3270 15 at at IN cord-015369-72cjogxz 3270 16 three three CD cord-015369-72cjogxz 3270 17 o'clock o'clock NN cord-015369-72cjogxz 3270 18 . . . cord-015369-72cjogxz 3271 1 The the DT cord-015369-72cjogxz 3271 2 staple staple JJ cord-015369-72cjogxz 3271 3 line line NN cord-015369-72cjogxz 3271 4 falls fall VBZ cord-015369-72cjogxz 3271 5 spontaneously spontaneously RB cord-015369-72cjogxz 3271 6 into into IN cord-015369-72cjogxz 3271 7 place place NN cord-015369-72cjogxz 3271 8 and and CC cord-015369-72cjogxz 3271 9 is be VBZ cord-015369-72cjogxz 3271 10 oversewed oversew VBN cord-015369-72cjogxz 3271 11 with with IN cord-015369-72cjogxz 3271 12 8 8 CD cord-015369-72cjogxz 3271 13 absorbable absorbable JJ cord-015369-72cjogxz 3271 14 monofil monofil NN cord-015369-72cjogxz 3271 15 sutures suture NNS cord-015369-72cjogxz 3271 16 to to TO cord-015369-72cjogxz 3271 17 strengthen strengthen VB cord-015369-72cjogxz 3271 18 it -PRON- PRP cord-015369-72cjogxz 3271 19 and and CC cord-015369-72cjogxz 3271 20 ensure ensure VB cord-015369-72cjogxz 3271 21 hemostasis hemostasis NN cord-015369-72cjogxz 3271 22 . . . cord-015369-72cjogxz 3272 1 Results result NNS cord-015369-72cjogxz 3272 2 . . . cord-015369-72cjogxz 3273 1 In in IN cord-015369-72cjogxz 3273 2 a a DT cord-015369-72cjogxz 3273 3 feasibility feasibility NN cord-015369-72cjogxz 3273 4 study study NN cord-015369-72cjogxz 3273 5 has have VBZ cord-015369-72cjogxz 3273 6 been be VBN cord-015369-72cjogxz 3273 7 shown show VBN cord-015369-72cjogxz 3273 8 , , , cord-015369-72cjogxz 3273 9 that that IN cord-015369-72cjogxz 3273 10 the the DT cord-015369-72cjogxz 3273 11 PSP PSP NNP cord-015369-72cjogxz 3273 12 procedure procedure NN cord-015369-72cjogxz 3273 13 is be VBZ cord-015369-72cjogxz 3273 14 easy easy JJ cord-015369-72cjogxz 3273 15 to to TO cord-015369-72cjogxz 3273 16 perform perform VB cord-015369-72cjogxz 3273 17 , , , cord-015369-72cjogxz 3273 18 safe safe JJ cord-015369-72cjogxz 3273 19 and and CC cord-015369-72cjogxz 3273 20 does do VBZ cord-015369-72cjogxz 3273 21 n't not RB cord-015369-72cjogxz 3273 22 need need VB cord-015369-72cjogxz 3273 23 a a DT cord-015369-72cjogxz 3273 24 lot lot NN cord-015369-72cjogxz 3273 25 of of IN cord-015369-72cjogxz 3273 26 time time NN cord-015369-72cjogxz 3273 27 [ [ -LRB- cord-015369-72cjogxz 3273 28 1 1 CD cord-015369-72cjogxz 3273 29 ] ] -RRB- cord-015369-72cjogxz 3273 30 . . . cord-015369-72cjogxz 3274 1 We -PRON- PRP cord-015369-72cjogxz 3274 2 present present VBP cord-015369-72cjogxz 3274 3 the the DT cord-015369-72cjogxz 3274 4 correct correct JJ cord-015369-72cjogxz 3274 5 operation operation NN cord-015369-72cjogxz 3274 6 technique technique NN cord-015369-72cjogxz 3274 7 . . . cord-015369-72cjogxz 3275 1 Important important JJ cord-015369-72cjogxz 3275 2 steps step NNS cord-015369-72cjogxz 3275 3 are be VBP cord-015369-72cjogxz 3275 4 emphasized emphasize VBN cord-015369-72cjogxz 3275 5 and and CC cord-015369-72cjogxz 3275 6 pitfalls pitfall NNS cord-015369-72cjogxz 3275 7 explained explain VBD cord-015369-72cjogxz 3275 8 . . . cord-015369-72cjogxz 3276 1 Conclusions conclusion NNS cord-015369-72cjogxz 3276 2 . . . cord-015369-72cjogxz 3277 1 The the DT cord-015369-72cjogxz 3277 2 video video NN cord-015369-72cjogxz 3277 3 shows show VBZ cord-015369-72cjogxz 3277 4 the the DT cord-015369-72cjogxz 3277 5 PSP PSP NNP cord-015369-72cjogxz 3277 6 procedure procedure NN cord-015369-72cjogxz 3277 7 and and CC cord-015369-72cjogxz 3277 8 how how WRB cord-015369-72cjogxz 3277 9 it -PRON- PRP cord-015369-72cjogxz 3277 10 's be VBZ cord-015369-72cjogxz 3277 11 done do VBN cord-015369-72cjogxz 3277 12 . . . cord-015369-72cjogxz 3278 1 Clinical clinical JJ cord-015369-72cjogxz 3278 2 investigations investigation NNS cord-015369-72cjogxz 3278 3 proved prove VBD cord-015369-72cjogxz 3278 4 the the DT cord-015369-72cjogxz 3278 5 feasibility feasibility NN cord-015369-72cjogxz 3278 6 of of IN cord-015369-72cjogxz 3278 7 the the DT cord-015369-72cjogxz 3278 8 Transtar Transtar NNP cord-015369-72cjogxz 3278 9 procedure procedure NN cord-015369-72cjogxz 3278 10 . . . cord-015369-72cjogxz 3279 1 It -PRON- PRP cord-015369-72cjogxz 3279 2 is be VBZ cord-015369-72cjogxz 3279 3 a a DT cord-015369-72cjogxz 3279 4 safe safe JJ cord-015369-72cjogxz 3279 5 and and CC cord-015369-72cjogxz 3279 6 effective effective JJ cord-015369-72cjogxz 3279 7 treatment treatment NN cord-015369-72cjogxz 3279 8 for for IN cord-015369-72cjogxz 3279 9 patients patient NNS cord-015369-72cjogxz 3279 10 with with IN cord-015369-72cjogxz 3279 11 ODS ODS NNP cord-015369-72cjogxz 3279 12 . . . cord-015369-72cjogxz 3280 1 The the DT cord-015369-72cjogxz 3280 2 aim aim NN cord-015369-72cjogxz 3280 3 of of IN cord-015369-72cjogxz 3280 4 the the DT cord-015369-72cjogxz 3280 5 presented present VBN cord-015369-72cjogxz 3280 6 study study NN cord-015369-72cjogxz 3280 7 is be VBZ cord-015369-72cjogxz 3280 8 to to TO cord-015369-72cjogxz 3280 9 access access VB cord-015369-72cjogxz 3280 10 the the DT cord-015369-72cjogxz 3280 11 functional functional JJ cord-015369-72cjogxz 3280 12 outcome outcome NN cord-015369-72cjogxz 3280 13 after after IN cord-015369-72cjogxz 3280 14 the the DT cord-015369-72cjogxz 3280 15 procedure procedure NN cord-015369-72cjogxz 3280 16 and and CC cord-015369-72cjogxz 3280 17 its -PRON- PRP$ cord-015369-72cjogxz 3280 18 impact impact NN cord-015369-72cjogxz 3280 19 on on IN cord-015369-72cjogxz 3280 20 quality quality NN cord-015369-72cjogxz 3280 21 of of IN cord-015369-72cjogxz 3280 22 life life NN cord-015369-72cjogxz 3280 23 . . . cord-015369-72cjogxz 3281 1 Methods method NNS cord-015369-72cjogxz 3281 2 . . . cord-015369-72cjogxz 3282 1 Female female JJ cord-015369-72cjogxz 3282 2 patients patient NNS cord-015369-72cjogxz 3282 3 presenting present VBG cord-015369-72cjogxz 3282 4 with with IN cord-015369-72cjogxz 3282 5 ODS ODS NNP cord-015369-72cjogxz 3282 6 were be VBD cord-015369-72cjogxz 3282 7 enrolled enrol VBN cord-015369-72cjogxz 3282 8 prospectively prospectively RB cord-015369-72cjogxz 3282 9 for for IN cord-015369-72cjogxz 3282 10 the the DT cord-015369-72cjogxz 3282 11 Transtar Transtar NNP cord-015369-72cjogxz 3282 12 procedure procedure NN cord-015369-72cjogxz 3282 13 . . . cord-015369-72cjogxz 3283 1 Intussuseption Intussuseption NNP cord-015369-72cjogxz 3283 2 and/or and/or CC cord-015369-72cjogxz 3283 3 anterior anterior JJ cord-015369-72cjogxz 3283 4 rectocele rectocele NN cord-015369-72cjogxz 3283 5 were be VBD cord-015369-72cjogxz 3283 6 confirmed confirm VBN cord-015369-72cjogxz 3283 7 by by IN cord-015369-72cjogxz 3283 8 clinical clinical JJ cord-015369-72cjogxz 3283 9 investigation investigation NN cord-015369-72cjogxz 3283 10 and and CC cord-015369-72cjogxz 3283 11 by by IN cord-015369-72cjogxz 3283 12 MRDefecography MRDefecography NNP cord-015369-72cjogxz 3283 13 . . . cord-015369-72cjogxz 3284 1 Functional functional JJ cord-015369-72cjogxz 3284 2 outcome outcome NN cord-015369-72cjogxz 3284 3 was be VBD cord-015369-72cjogxz 3284 4 measured measure VBN cord-015369-72cjogxz 3284 5 by by IN cord-015369-72cjogxz 3284 6 ODS ODS NNP cord-015369-72cjogxz 3284 7 - - HYPH cord-015369-72cjogxz 3284 8 Score Score NNP cord-015369-72cjogxz 3284 9 , , , cord-015369-72cjogxz 3284 10 Severity severity NN cord-015369-72cjogxz 3284 11 of of IN cord-015369-72cjogxz 3284 12 Symptoms Symptoms NNP cord-015369-72cjogxz 3284 13 Score Score NNP cord-015369-72cjogxz 3284 14 ( ( -LRB- cord-015369-72cjogxz 3284 15 SSS SSS NNP cord-015369-72cjogxz 3284 16 ) ) -RRB- cord-015369-72cjogxz 3284 17 and and CC cord-015369-72cjogxz 3284 18 Wexner Wexner NNP cord-015369-72cjogxz 3284 19 Score Score NNP cord-015369-72cjogxz 3284 20 at at IN cord-015369-72cjogxz 3284 21 3 3 CD cord-015369-72cjogxz 3284 22 months month NNS cord-015369-72cjogxz 3284 23 postoperatively postoperatively RB cord-015369-72cjogxz 3284 24 . . . cord-015369-72cjogxz 3285 1 Quality quality NN cord-015369-72cjogxz 3285 2 of of IN cord-015369-72cjogxz 3285 3 life life NN cord-015369-72cjogxz 3285 4 was be VBD cord-015369-72cjogxz 3285 5 accessed access VBN cord-015369-72cjogxz 3285 6 by by IN cord-015369-72cjogxz 3285 7 the the DT cord-015369-72cjogxz 3285 8 Cleveland Cleveland NNP cord-015369-72cjogxz 3285 9 Clinical Clinical NNP cord-015369-72cjogxz 3285 10 Obstipation Obstipation NNP cord-015369-72cjogxz 3285 11 Score Score NNP cord-015369-72cjogxz 3285 12 ( ( -LRB- cord-015369-72cjogxz 3285 13 CCOS CCOS NNP cord-015369-72cjogxz 3285 14 ) ) -RRB- cord-015369-72cjogxz 3285 15 , , , cord-015369-72cjogxz 3285 16 the the DT cord-015369-72cjogxz 3285 17 Gastrointestinal Gastrointestinal NNP cord-015369-72cjogxz 3285 18 Quality Quality NNP cord-015369-72cjogxz 3285 19 of of IN cord-015369-72cjogxz 3285 20 Life Life NNP cord-015369-72cjogxz 3285 21 Index Index NNP cord-015369-72cjogxz 3285 22 ( ( -LRB- cord-015369-72cjogxz 3285 23 GLQI GLQI NNP cord-015369-72cjogxz 3285 24 ) ) -RRB- cord-015369-72cjogxz 3285 25 , , , cord-015369-72cjogxz 3285 26 the the DT cord-015369-72cjogxz 3285 27 American American NNP cord-015369-72cjogxz 3285 28 Society Society NNP cord-015369-72cjogxz 3285 29 of of IN cord-015369-72cjogxz 3285 30 Colorectal Colorectal NNP cord-015369-72cjogxz 3285 31 Surgeons Surgeons NNPS cord-015369-72cjogxz 3285 32 Score Score NNP cord-015369-72cjogxz 3285 33 ( ( -LRB- cord-015369-72cjogxz 3285 34 ASCRS ASCRS NNP cord-015369-72cjogxz 3285 35 ) ) -RRB- cord-015369-72cjogxz 3285 36 and and CC cord-015369-72cjogxz 3285 37 the the DT cord-015369-72cjogxz 3285 38 SF-36 SF-36 NNP cord-015369-72cjogxz 3285 39 6 6 CD cord-015369-72cjogxz 3285 40 months month NNS cord-015369-72cjogxz 3285 41 postoperatively postoperatively RB cord-015369-72cjogxz 3285 42 . . . cord-015369-72cjogxz 3286 1 Results result NNS cord-015369-72cjogxz 3286 2 . . . cord-015369-72cjogxz 3287 1 Between between IN cord-015369-72cjogxz 3287 2 January January NNP cord-015369-72cjogxz 3287 3 2007 2007 CD cord-015369-72cjogxz 3287 4 and and CC cord-015369-72cjogxz 3287 5 November November NNP cord-015369-72cjogxz 3287 6 2008 2008 CD cord-015369-72cjogxz 3287 7 45 45 CD cord-015369-72cjogxz 3287 8 consecutive consecutive JJ cord-015369-72cjogxz 3287 9 patients patient NNS cord-015369-72cjogxz 3287 10 , , , cord-015369-72cjogxz 3287 11 median median JJ cord-015369-72cjogxz 3287 12 age age NN cord-015369-72cjogxz 3287 13 64 64 CD cord-015369-72cjogxz 3287 14 years year NNS cord-015369-72cjogxz 3287 15 ( ( -LRB- cord-015369-72cjogxz 3287 16 range range VBP cord-015369-72cjogxz 3287 17 20 20 CD cord-015369-72cjogxz 3287 18 - - SYM cord-015369-72cjogxz 3287 19 87 87 CD cord-015369-72cjogxz 3287 20 ) ) -RRB- cord-015369-72cjogxz 3287 21 were be VBD cord-015369-72cjogxz 3287 22 included include VBN cord-015369-72cjogxz 3287 23 . . . cord-015369-72cjogxz 3288 1 Eleven eleven CD cord-015369-72cjogxz 3288 2 patients patient NNS cord-015369-72cjogxz 3288 3 complained complain VBD cord-015369-72cjogxz 3288 4 preoperatively preoperatively RB cord-015369-72cjogxz 3288 5 fecal fecal JJ cord-015369-72cjogxz 3288 6 incontinence incontinence NN cord-015369-72cjogxz 3288 7 . . . cord-015369-72cjogxz 3289 1 Functional functional JJ cord-015369-72cjogxz 3289 2 scores score NNS cord-015369-72cjogxz 3289 3 improved improve VBD cord-015369-72cjogxz 3289 4 significantly significantly RB cord-015369-72cjogxz 3289 5 : : : cord-015369-72cjogxz 3289 6 ODS ODS NNP cord-015369-72cjogxz 3289 7 decreased decrease VBD cord-015369-72cjogxz 3289 8 from from IN cord-015369-72cjogxz 3289 9 a a DT cord-015369-72cjogxz 3289 10 median median NN cord-015369-72cjogxz 3289 11 of of IN cord-015369-72cjogxz 3289 12 14 14 CD cord-015369-72cjogxz 3289 13 ( ( -LRB- cord-015369-72cjogxz 3289 14 4 4 CD cord-015369-72cjogxz 3289 15 - - SYM cord-015369-72cjogxz 3289 16 18 18 CD cord-015369-72cjogxz 3289 17 ) ) -RRB- cord-015369-72cjogxz 3289 18 to to IN cord-015369-72cjogxz 3289 19 5 5 CD cord-015369-72cjogxz 3289 20 ( ( -LRB- cord-015369-72cjogxz 3289 21 2 2 CD cord-015369-72cjogxz 3289 22 - - SYM cord-015369-72cjogxz 3289 23 10 10 CD cord-015369-72cjogxz 3289 24 ) ) -RRB- cord-015369-72cjogxz 3289 25 after after IN cord-015369-72cjogxz 3289 26 6 6 CD cord-015369-72cjogxz 3289 27 weeks week NNS cord-015369-72cjogxz 3289 28 ( ( -LRB- cord-015369-72cjogxz 3289 29 p p NN cord-015369-72cjogxz 3289 30 < < XX cord-015369-72cjogxz 3289 31 0.0001 0.0001 CD cord-015369-72cjogxz 3289 32 ) ) -RRB- cord-015369-72cjogxz 3289 33 and and CC cord-015369-72cjogxz 3289 34 4 4 CD cord-015369-72cjogxz 3289 35 ( ( -LRB- cord-015369-72cjogxz 3289 36 2 2 CD cord-015369-72cjogxz 3289 37 - - SYM cord-015369-72cjogxz 3289 38 10 10 CD cord-015369-72cjogxz 3289 39 ) ) -RRB- cord-015369-72cjogxz 3289 40 after after IN cord-015369-72cjogxz 3289 41 3 3 CD cord-015369-72cjogxz 3289 42 months month NNS cord-015369-72cjogxz 3289 43 . . . cord-015369-72cjogxz 3290 1 SSS SSS NNP cord-015369-72cjogxz 3290 2 decreased decrease VBD cord-015369-72cjogxz 3290 3 form form NN cord-015369-72cjogxz 3290 4 14 14 CD cord-015369-72cjogxz 3290 5 ( ( -LRB- cord-015369-72cjogxz 3290 6 6 6 CD cord-015369-72cjogxz 3290 7 - - SYM cord-015369-72cjogxz 3290 8 21 21 CD cord-015369-72cjogxz 3290 9 ) ) -RRB- cord-015369-72cjogxz 3290 10 to to IN cord-015369-72cjogxz 3290 11 3 3 CD cord-015369-72cjogxz 3290 12 ( ( -LRB- cord-015369-72cjogxz 3290 13 0 0 CD cord-015369-72cjogxz 3290 14 - - SYM cord-015369-72cjogxz 3290 15 19 19 CD cord-015369-72cjogxz 3290 16 ) ) -RRB- cord-015369-72cjogxz 3290 17 after after IN cord-015369-72cjogxz 3290 18 6 6 CD cord-015369-72cjogxz 3290 19 weeks week NNS cord-015369-72cjogxz 3290 20 ( ( -LRB- cord-015369-72cjogxz 3290 21 p p NN cord-015369-72cjogxz 3290 22 < < XX cord-015369-72cjogxz 3290 23 0.0001 0.0001 CD cord-015369-72cjogxz 3290 24 ) ) -RRB- cord-015369-72cjogxz 3290 25 and and CC cord-015369-72cjogxz 3290 26 3 3 CD cord-015369-72cjogxz 3290 27 ( ( -LRB- cord-015369-72cjogxz 3290 28 0 0 CD cord-015369-72cjogxz 3290 29 - - SYM cord-015369-72cjogxz 3290 30 7 7 CD cord-015369-72cjogxz 3290 31 ) ) -RRB- cord-015369-72cjogxz 3290 32 after after IN cord-015369-72cjogxz 3290 33 3 3 CD cord-015369-72cjogxz 3290 34 months month NNS cord-015369-72cjogxz 3290 35 . . . cord-015369-72cjogxz 3291 1 Median Median NNP cord-015369-72cjogxz 3291 2 Wexner Wexner NNP cord-015369-72cjogxz 3291 3 score score NN cord-015369-72cjogxz 3291 4 was be VBD cord-015369-72cjogxz 3291 5 0 0 CD cord-015369-72cjogxz 3291 6 pre pre VB cord-015369-72cjogxz 3291 7 - - : cord-015369-72cjogxz 3291 8 and and CC cord-015369-72cjogxz 3291 9 postoperatively postoperatively RB cord-015369-72cjogxz 3292 1 ( ( -LRB- cord-015369-72cjogxz 3292 2 range range NN cord-015369-72cjogxz 3292 3 0 0 CD cord-015369-72cjogxz 3292 4 - - SYM cord-015369-72cjogxz 3292 5 10 10 CD cord-015369-72cjogxz 3292 6 and and CC cord-015369-72cjogxz 3292 7 0 0 CD cord-015369-72cjogxz 3292 8 - - SYM cord-015369-72cjogxz 3292 9 8 8 CD cord-015369-72cjogxz 3292 10 ) ) -RRB- cord-015369-72cjogxz 3292 11 . . . cord-015369-72cjogxz 3293 1 At at IN cord-015369-72cjogxz 3293 2 6 6 CD cord-015369-72cjogxz 3293 3 weeks week NNS cord-015369-72cjogxz 3293 4 10 10 CD cord-015369-72cjogxz 3293 5 patients patient NNS cord-015369-72cjogxz 3293 6 presented present VBD cord-015369-72cjogxz 3293 7 fecal fecal JJ cord-015369-72cjogxz 3293 8 incontinence incontinence NN cord-015369-72cjogxz 3293 9 and and CC cord-015369-72cjogxz 3293 10 12 12 CD cord-015369-72cjogxz 3293 11 patients patient NNS cord-015369-72cjogxz 3293 12 complained complain VBN cord-015369-72cjogxz 3293 13 of of IN cord-015369-72cjogxz 3293 14 fecal fecal JJ cord-015369-72cjogxz 3293 15 urgency urgency NN cord-015369-72cjogxz 3293 16 . . . cord-015369-72cjogxz 3294 1 At at IN cord-015369-72cjogxz 3294 2 3 3 CD cord-015369-72cjogxz 3294 3 months month NNS cord-015369-72cjogxz 3294 4 4 4 CD cord-015369-72cjogxz 3294 5 patients patient NNS cord-015369-72cjogxz 3294 6 were be VBD cord-015369-72cjogxz 3294 7 still still RB cord-015369-72cjogxz 3294 8 incontinent incontinent JJ cord-015369-72cjogxz 3294 9 , , , cord-015369-72cjogxz 3294 10 two two CD cord-015369-72cjogxz 3294 11 received receive VBD cord-015369-72cjogxz 3294 12 a a DT cord-015369-72cjogxz 3294 13 succesfully succesfully RB cord-015369-72cjogxz 3294 14 sacral sacral JJ cord-015369-72cjogxz 3294 15 neuromodulation neuromodulation NN cord-015369-72cjogxz 3294 16 . . . cord-015369-72cjogxz 3295 1 Fecal fecal JJ cord-015369-72cjogxz 3295 2 urgency urgency NN cord-015369-72cjogxz 3295 3 persisted persist VBD cord-015369-72cjogxz 3295 4 in in IN cord-015369-72cjogxz 3295 5 4 4 CD cord-015369-72cjogxz 3295 6 patients patient NNS cord-015369-72cjogxz 3295 7 . . . cord-015369-72cjogxz 3296 1 Quality quality NN cord-015369-72cjogxz 3296 2 of of IN cord-015369-72cjogxz 3296 3 life life NN cord-015369-72cjogxz 3296 4 improved improve VBD cord-015369-72cjogxz 3296 5 significantly significantly RB cord-015369-72cjogxz 3296 6 : : : cord-015369-72cjogxz 3296 7 CCOS CCOS NNP cord-015369-72cjogxz 3296 8 ( ( -LRB- cord-015369-72cjogxz 3296 9 p p NN cord-015369-72cjogxz 3296 10 < < XX cord-015369-72cjogxz 3296 11 0.00006 0.00006 CD cord-015369-72cjogxz 3296 12 ) ) -RRB- cord-015369-72cjogxz 3296 13 , , , cord-015369-72cjogxz 3296 14 GLQI GLQI NNP cord-015369-72cjogxz 3296 15 ( ( -LRB- cord-015369-72cjogxz 3296 16 p p NN cord-015369-72cjogxz 3296 17 < < XX cord-015369-72cjogxz 3296 18 0.003 0.003 CD cord-015369-72cjogxz 3296 19 ) ) -RRB- cord-015369-72cjogxz 3296 20 and and CC cord-015369-72cjogxz 3296 21 SF-36 SF-36 NNP cord-015369-72cjogxz 3296 22 ( ( -LRB- cord-015369-72cjogxz 3296 23 p p NN cord-015369-72cjogxz 3296 24 < < XX cord-015369-72cjogxz 3296 25 0.008 0.008 CD cord-015369-72cjogxz 3296 26 ) ) -RRB- cord-015369-72cjogxz 3296 27 . . . cord-015369-72cjogxz 3297 1 In in IN cord-015369-72cjogxz 3297 2 ASCRS ASCRS NNP cord-015369-72cjogxz 3297 3 self self NN cord-015369-72cjogxz 3297 4 - - HYPH cord-015369-72cjogxz 3297 5 esteem esteem NN cord-015369-72cjogxz 3297 6 improved improve VBD cord-015369-72cjogxz 3297 7 ( ( -LRB- cord-015369-72cjogxz 3297 8 p p NN cord-015369-72cjogxz 3297 9 < < XX cord-015369-72cjogxz 3297 10 0.003 0.003 CD cord-015369-72cjogxz 3297 11 ) ) -RRB- cord-015369-72cjogxz 3297 12 , , , cord-015369-72cjogxz 3297 13 the the DT cord-015369-72cjogxz 3297 14 other other JJ cord-015369-72cjogxz 3297 15 aspects aspect NNS cord-015369-72cjogxz 3297 16 did do VBD cord-015369-72cjogxz 3297 17 n't not RB cord-015369-72cjogxz 3297 18 change change VB cord-015369-72cjogxz 3297 19 significantly significantly RB cord-015369-72cjogxz 3297 20 . . . cord-015369-72cjogxz 3298 1 Conclusions conclusion NNS cord-015369-72cjogxz 3298 2 . . . cord-015369-72cjogxz 3299 1 The the DT cord-015369-72cjogxz 3299 2 Transtar Transtar NNP cord-015369-72cjogxz 3299 3 procedure procedure NN cord-015369-72cjogxz 3299 4 is be VBZ cord-015369-72cjogxz 3299 5 an an DT cord-015369-72cjogxz 3299 6 effective effective JJ cord-015369-72cjogxz 3299 7 treatment treatment NN cord-015369-72cjogxz 3299 8 for for IN cord-015369-72cjogxz 3299 9 patients patient NNS cord-015369-72cjogxz 3299 10 with with IN cord-015369-72cjogxz 3299 11 severe severe JJ cord-015369-72cjogxz 3299 12 ODS ODS NNP cord-015369-72cjogxz 3299 13 and and CC cord-015369-72cjogxz 3299 14 improves improve VBZ cord-015369-72cjogxz 3299 15 quality quality NN cord-015369-72cjogxz 3299 16 of of IN cord-015369-72cjogxz 3299 17 life life NN cord-015369-72cjogxz 3299 18 significantly significantly RB cord-015369-72cjogxz 3299 19 . . . cord-015369-72cjogxz 3300 1 However however RB cord-015369-72cjogxz 3300 2 , , , cord-015369-72cjogxz 3300 3 some some DT cord-015369-72cjogxz 3300 4 patients patient NNS cord-015369-72cjogxz 3300 5 suffer suffer VBP cord-015369-72cjogxz 3300 6 of of IN cord-015369-72cjogxz 3300 7 incontinence incontinence NN cord-015369-72cjogxz 3300 8 and and CC cord-015369-72cjogxz 3300 9 fecal fecal JJ cord-015369-72cjogxz 3300 10 urgency urgency NN cord-015369-72cjogxz 3300 11 in in IN cord-015369-72cjogxz 3300 12 the the DT cord-015369-72cjogxz 3300 13 first first JJ cord-015369-72cjogxz 3300 14 weeks week NNS cord-015369-72cjogxz 3300 15 after after IN cord-015369-72cjogxz 3300 16 the the DT cord-015369-72cjogxz 3300 17 operation operation NN cord-015369-72cjogxz 3300 18 . . . cord-015369-72cjogxz 3301 1 In in IN cord-015369-72cjogxz 3301 2 most most JJS cord-015369-72cjogxz 3301 3 of of IN cord-015369-72cjogxz 3301 4 these these DT cord-015369-72cjogxz 3301 5 the the DT cord-015369-72cjogxz 3301 6 symptoms symptom NNS cord-015369-72cjogxz 3301 7 dissolve dissolve VBP cord-015369-72cjogxz 3301 8 without without IN cord-015369-72cjogxz 3301 9 further further JJ cord-015369-72cjogxz 3301 10 operative operative JJ cord-015369-72cjogxz 3301 11 treatment treatment NN cord-015369-72cjogxz 3301 12 . . . cord-015369-72cjogxz 3302 1 Background background NN cord-015369-72cjogxz 3302 2 . . . cord-015369-72cjogxz 3303 1 In in IN cord-015369-72cjogxz 3303 2 gastric gastric JJ cord-015369-72cjogxz 3303 3 cancer cancer NN cord-015369-72cjogxz 3303 4 , , , cord-015369-72cjogxz 3303 5 peritoneal peritoneal JJ cord-015369-72cjogxz 3303 6 carcinomatosis carcinomatosis NN cord-015369-72cjogxz 3303 7 is be VBZ cord-015369-72cjogxz 3303 8 a a DT cord-015369-72cjogxz 3303 9 frequent frequent JJ cord-015369-72cjogxz 3303 10 finding finding NN cord-015369-72cjogxz 3303 11 and and CC cord-015369-72cjogxz 3303 12 associated associate VBN cord-015369-72cjogxz 3303 13 with with IN cord-015369-72cjogxz 3303 14 a a DT cord-015369-72cjogxz 3303 15 poor poor JJ cord-015369-72cjogxz 3303 16 prognosis prognosis NN cord-015369-72cjogxz 3303 17 . . . cord-015369-72cjogxz 3304 1 The the DT cord-015369-72cjogxz 3304 2 enhanced enhanced JJ cord-015369-72cjogxz 3304 3 expression expression NN cord-015369-72cjogxz 3304 4 of of IN cord-015369-72cjogxz 3304 5 phosphoglycerate phosphoglycerate NN cord-015369-72cjogxz 3304 6 - - HYPH cord-015369-72cjogxz 3304 7 kinase-1 kinase-1 NNP cord-015369-72cjogxz 3304 8 ( ( -LRB- cord-015369-72cjogxz 3304 9 PGK1 PGK1 NNP cord-015369-72cjogxz 3304 10 ) ) -RRB- cord-015369-72cjogxz 3304 11 and and CC cord-015369-72cjogxz 3304 12 its -PRON- PRP$ cord-015369-72cjogxz 3304 13 signalling signal VBG cord-015369-72cjogxz 3304 14 targets target NNS cord-015369-72cjogxz 3304 15 chemokine chemokine NN cord-015369-72cjogxz 3304 16 - - : cord-015369-72cjogxz 3304 17 receptor-4 receptor-4 NN cord-015369-72cjogxz 3304 18 ( ( -LRB- cord-015369-72cjogxz 3304 19 CXCR4 CXCR4 NNP cord-015369-72cjogxz 3304 20 ) ) -RRB- cord-015369-72cjogxz 3304 21 and and CC cord-015369-72cjogxz 3304 22 its -PRON- PRP$ cord-015369-72cjogxz 3304 23 ligand ligand NN cord-015369-72cjogxz 3304 24 CXCL12 CXCL12 NNP cord-015369-72cjogxz 3304 25 seem seem VBP cord-015369-72cjogxz 3304 26 to to TO cord-015369-72cjogxz 3304 27 play play VB cord-015369-72cjogxz 3304 28 a a DT cord-015369-72cjogxz 3304 29 crucial crucial JJ cord-015369-72cjogxz 3304 30 role role NN cord-015369-72cjogxz 3304 31 in in IN cord-015369-72cjogxz 3304 32 enabling enable VBG cord-015369-72cjogxz 3304 33 diffuse diffuse JJ cord-015369-72cjogxz 3304 34 primary primary JJ cord-015369-72cjogxz 3304 35 gastric gastric JJ cord-015369-72cjogxz 3304 36 tumours tumour NNS cord-015369-72cjogxz 3304 37 to to TO cord-015369-72cjogxz 3304 38 develop develop VB cord-015369-72cjogxz 3304 39 peritoneal peritoneal JJ cord-015369-72cjogxz 3304 40 dissemination dissemination NN cord-015369-72cjogxz 3304 41 . . . cord-015369-72cjogxz 3305 1 Methods method NNS cord-015369-72cjogxz 3305 2 . . . cord-015369-72cjogxz 3306 1 Comparative comparative JJ cord-015369-72cjogxz 3306 2 microarray microarray NN cord-015369-72cjogxz 3306 3 analysis analysis NN cord-015369-72cjogxz 3306 4 was be VBD cord-015369-72cjogxz 3306 5 conducted conduct VBN cord-015369-72cjogxz 3306 6 investigating investigate VBG cord-015369-72cjogxz 3306 7 human human JJ cord-015369-72cjogxz 3306 8 specimens specimen NNS cord-015369-72cjogxz 3306 9 from from IN cord-015369-72cjogxz 3306 10 consecutive consecutive JJ cord-015369-72cjogxz 3306 11 gastric gastric JJ cord-015369-72cjogxz 3306 12 cancer cancer NN cord-015369-72cjogxz 3306 13 patients patient NNS cord-015369-72cjogxz 3306 14 with with IN cord-015369-72cjogxz 3306 15 peritoneal peritoneal JJ cord-015369-72cjogxz 3306 16 carcinomatosis carcinomatosis NN cord-015369-72cjogxz 3306 17 versus versus IN cord-015369-72cjogxz 3306 18 gastric gastric JJ cord-015369-72cjogxz 3306 19 cancer cancer NN cord-015369-72cjogxz 3306 20 samples sample NNS cord-015369-72cjogxz 3306 21 without without IN cord-015369-72cjogxz 3306 22 peritoneal peritoneal JJ cord-015369-72cjogxz 3306 23 carcinomatosis carcinomatosis NN cord-015369-72cjogxz 3306 24 . . . cord-015369-72cjogxz 3307 1 Subsequently subsequently RB cord-015369-72cjogxz 3307 2 selected select VBD cord-015369-72cjogxz 3307 3 target target NN cord-015369-72cjogxz 3307 4 genes gene NNS cord-015369-72cjogxz 3307 5 were be VBD cord-015369-72cjogxz 3307 6 evaluated evaluate VBN cord-015369-72cjogxz 3307 7 using use VBG cord-015369-72cjogxz 3307 8 quantitative quantitative JJ cord-015369-72cjogxz 3307 9 real real JJ cord-015369-72cjogxz 3307 10 - - HYPH cord-015369-72cjogxz 3307 11 time time NN cord-015369-72cjogxz 3307 12 polymerase polymerase NN cord-015369-72cjogxz 3307 13 chain chain NN cord-015369-72cjogxz 3307 14 reaction reaction NN cord-015369-72cjogxz 3307 15 ( ( -LRB- cord-015369-72cjogxz 3307 16 qRT qRT NNP cord-015369-72cjogxz 3307 17 - - HYPH cord-015369-72cjogxz 3307 18 PCR PCR NNP cord-015369-72cjogxz 3307 19 ) ) -RRB- cord-015369-72cjogxz 3307 20 . . . cord-015369-72cjogxz 3308 1 Further further RB cord-015369-72cjogxz 3308 2 , , , cord-015369-72cjogxz 3308 3 , , , cord-015369-72cjogxz 3308 4 genesilencing genesilence VBG cord-015369-72cjogxz 3308 5 ' ' '' cord-015369-72cjogxz 3308 6 ' ' '' cord-015369-72cjogxz 3308 7 ( ( -LRB- cord-015369-72cjogxz 3308 8 siRNA sirna NN cord-015369-72cjogxz 3308 9 - - HYPH cord-015369-72cjogxz 3308 10 knock knock NN cord-015369-72cjogxz 3308 11 - - HYPH cord-015369-72cjogxz 3308 12 down down NN cord-015369-72cjogxz 3308 13 ) ) -RRB- cord-015369-72cjogxz 3308 14 concerning concern VBG cord-015369-72cjogxz 3308 15 CXCR4 CXCR4 NNS cord-015369-72cjogxz 3308 16 and and CC cord-015369-72cjogxz 3308 17 PGK1 PGK1 NNP cord-015369-72cjogxz 3308 18 and and CC cord-015369-72cjogxz 3308 19 transfection transfection NN cord-015369-72cjogxz 3308 20 ( ( -LRB- cord-015369-72cjogxz 3308 21 overexoression overexoression NN cord-015369-72cjogxz 3308 22 ) ) -RRB- cord-015369-72cjogxz 3308 23 of of IN cord-015369-72cjogxz 3308 24 PGK1 PGK1 NNP cord-015369-72cjogxz 3308 25 was be VBD cord-015369-72cjogxz 3308 26 performed perform VBN cord-015369-72cjogxz 3308 27 . . . cord-015369-72cjogxz 3309 1 The the DT cord-015369-72cjogxz 3309 2 obtained obtain VBN cord-015369-72cjogxz 3309 3 results result NNS cord-015369-72cjogxz 3309 4 were be VBD cord-015369-72cjogxz 3309 5 further further RB cord-015369-72cjogxz 3309 6 confirmed confirm VBN cord-015369-72cjogxz 3309 7 using use VBG cord-015369-72cjogxz 3309 8 Western western JJ cord-015369-72cjogxz 3309 9 - - HYPH cord-015369-72cjogxz 3309 10 Blot blot NN cord-015369-72cjogxz 3309 11 , , , cord-015369-72cjogxz 3309 12 FACS FACS NNP cord-015369-72cjogxz 3309 13 - - HYPH cord-015369-72cjogxz 3309 14 analysis analysis NN cord-015369-72cjogxz 3309 15 and and CC cord-015369-72cjogxz 3309 16 invasion invasion NN cord-015369-72cjogxz 3309 17 assays assay NNS cord-015369-72cjogxz 3309 18 . . . cord-015369-72cjogxz 3310 1 Results result NNS cord-015369-72cjogxz 3310 2 . . . cord-015369-72cjogxz 3311 1 The the DT cord-015369-72cjogxz 3311 2 microarray microarray NN cord-015369-72cjogxz 3311 3 analysis analysis NN cord-015369-72cjogxz 3311 4 revealed reveal VBD cord-015369-72cjogxz 3311 5 a a DT cord-015369-72cjogxz 3311 6 significant significant JJ cord-015369-72cjogxz 3311 7 overexpression overexpression NN cord-015369-72cjogxz 3311 8 of of IN cord-015369-72cjogxz 3311 9 PGK1 PGK1 NNP cord-015369-72cjogxz 3311 10 , , , cord-015369-72cjogxz 3311 11 CXCR4 CXCR4 NNP cord-015369-72cjogxz 3311 12 and and CC cord-015369-72cjogxz 3311 13 its -PRON- PRP$ cord-015369-72cjogxz 3311 14 ligand ligand NN cord-015369-72cjogxz 3311 15 CXCL12 CXCL12 NNP cord-015369-72cjogxz 3311 16 in in IN cord-015369-72cjogxz 3311 17 specimens specimen NNS cord-015369-72cjogxz 3311 18 from from IN cord-015369-72cjogxz 3311 19 gastric gastric JJ cord-015369-72cjogxz 3311 20 cancer cancer NN cord-015369-72cjogxz 3311 21 patients patient NNS cord-015369-72cjogxz 3311 22 with with IN cord-015369-72cjogxz 3311 23 peritoneal peritoneal JJ cord-015369-72cjogxz 3311 24 carcinomatosis carcinomatosis NN cord-015369-72cjogxz 3311 25 . . . cord-015369-72cjogxz 3312 1 Further further RB cord-015369-72cjogxz 3312 2 , , , cord-015369-72cjogxz 3312 3 , , , cord-015369-72cjogxz 3312 4 genesilencing genesilence VBG cord-015369-72cjogxz 3312 5 ' ' '' cord-015369-72cjogxz 3312 6 ' ' '' cord-015369-72cjogxz 3312 7 of of IN cord-015369-72cjogxz 3312 8 PGK1 PGK1 NNP cord-015369-72cjogxz 3312 9 and and CC cord-015369-72cjogxz 3312 10 CXCR4 CXCR4 NNP cord-015369-72cjogxz 3312 11 showed show VBD cord-015369-72cjogxz 3312 12 a a DT cord-015369-72cjogxz 3312 13 significant significant JJ cord-015369-72cjogxz 3312 14 co co NN cord-015369-72cjogxz 3312 15 - - NN cord-015369-72cjogxz 3312 16 regulation regulation NN cord-015369-72cjogxz 3312 17 on on IN cord-015369-72cjogxz 3312 18 expression expression NN cord-015369-72cjogxz 3312 19 and and CC cord-015369-72cjogxz 3312 20 protein protein NN cord-015369-72cjogxz 3312 21 level level NN cord-015369-72cjogxz 3312 22 in in IN cord-015369-72cjogxz 3312 23 vitro vitro FW cord-015369-72cjogxz 3312 24 . . . cord-015369-72cjogxz 3313 1 The the DT cord-015369-72cjogxz 3313 2 transfection transfection NN cord-015369-72cjogxz 3313 3 ( ( -LRB- cord-015369-72cjogxz 3313 4 overexoression overexoression NN cord-015369-72cjogxz 3313 5 ) ) -RRB- cord-015369-72cjogxz 3313 6 of of IN cord-015369-72cjogxz 3313 7 PGK1 PGK1 NNP cord-015369-72cjogxz 3313 8 also also RB cord-015369-72cjogxz 3313 9 revealed reveal VBD cord-015369-72cjogxz 3313 10 a a DT cord-015369-72cjogxz 3313 11 significant significant JJ cord-015369-72cjogxz 3313 12 upregulation upregulation NN cord-015369-72cjogxz 3313 13 of of IN cord-015369-72cjogxz 3313 14 its -PRON- PRP$ cord-015369-72cjogxz 3313 15 signalling signal VBG cord-015369-72cjogxz 3313 16 targets target NNS cord-015369-72cjogxz 3313 17 CXCR4 CXCR4 NNS cord-015369-72cjogxz 3313 18 and and CC cord-015369-72cjogxz 3313 19 its -PRON- PRP$ cord-015369-72cjogxz 3313 20 ligand ligand NN cord-015369-72cjogxz 3313 21 CXCL12 CXCL12 NNP cord-015369-72cjogxz 3313 22 on on IN cord-015369-72cjogxz 3313 23 expression expression NN cord-015369-72cjogxz 3313 24 and and CC cord-015369-72cjogxz 3313 25 protein protein NN cord-015369-72cjogxz 3313 26 level level NN cord-015369-72cjogxz 3313 27 . . . cord-015369-72cjogxz 3314 1 In in IN cord-015369-72cjogxz 3314 2 addition addition NN cord-015369-72cjogxz 3314 3 the the DT cord-015369-72cjogxz 3314 4 transfected transfecte VBN cord-015369-72cjogxz 3314 5 cells cell NNS cord-015369-72cjogxz 3314 6 showed show VBD cord-015369-72cjogxz 3314 7 a a DT cord-015369-72cjogxz 3314 8 50-fold 50-fold JJ cord-015369-72cjogxz 3314 9 distinctive distinctive JJ cord-015369-72cjogxz 3314 10 property property NN cord-015369-72cjogxz 3314 11 in in IN cord-015369-72cjogxz 3314 12 the the DT cord-015369-72cjogxz 3314 13 invasion invasion NN cord-015369-72cjogxz 3314 14 assay assay NN cord-015369-72cjogxz 3314 15 compared compare VBN cord-015369-72cjogxz 3314 16 to to IN cord-015369-72cjogxz 3314 17 cancer cancer NN cord-015369-72cjogxz 3314 18 cells cell NNS cord-015369-72cjogxz 3314 19 without without IN cord-015369-72cjogxz 3314 20 PGK1 PGK1 NNP cord-015369-72cjogxz 3314 21 overexpression overexpression NN cord-015369-72cjogxz 3314 22 . . . cord-015369-72cjogxz 3315 1 Conclusions conclusion NNS cord-015369-72cjogxz 3315 2 . . . cord-015369-72cjogxz 3316 1 Overexpression Overexpression NNP cord-015369-72cjogxz 3316 2 of of IN cord-015369-72cjogxz 3316 3 PGK1 PGK1 NNP cord-015369-72cjogxz 3316 4 and and CC cord-015369-72cjogxz 3316 5 its -PRON- PRP$ cord-015369-72cjogxz 3316 6 signalling signal VBG cord-015369-72cjogxz 3316 7 targets target NNS cord-015369-72cjogxz 3316 8 CXCR4 CXCR4 NNS cord-015369-72cjogxz 3316 9 and and CC cord-015369-72cjogxz 3316 10 CXCL12 CXCL12 NNP cord-015369-72cjogxz 3316 11 in in IN cord-015369-72cjogxz 3316 12 peritoneal peritoneal JJ cord-015369-72cjogxz 3316 13 disseminated disseminate VBN cord-015369-72cjogxz 3316 14 primary primary JJ cord-015369-72cjogxz 3316 15 gastric gastric JJ cord-015369-72cjogxz 3316 16 carcinomas carcinoma NNS cord-015369-72cjogxz 3316 17 sustainable sustainable JJ cord-015369-72cjogxz 3316 18 indicate indicate VBP cord-015369-72cjogxz 3316 19 a a DT cord-015369-72cjogxz 3316 20 promising promising JJ cord-015369-72cjogxz 3316 21 regulationpathway regulationpathway NN cord-015369-72cjogxz 3316 22 promoting promote VBG cord-015369-72cjogxz 3316 23 peritoneal peritoneal JJ cord-015369-72cjogxz 3316 24 dissemination dissemination NN cord-015369-72cjogxz 3316 25 . . . cord-015369-72cjogxz 3317 1 This this DT cord-015369-72cjogxz 3317 2 data datum NNS cord-015369-72cjogxz 3317 3 may may MD cord-015369-72cjogxz 3317 4 provide provide VB cord-015369-72cjogxz 3317 5 new new JJ cord-015369-72cjogxz 3317 6 prognostic prognostic JJ cord-015369-72cjogxz 3317 7 markers marker NNS cord-015369-72cjogxz 3317 8 and/or and/or CC cord-015369-72cjogxz 3317 9 potential potential JJ cord-015369-72cjogxz 3317 10 therapeutic therapeutic JJ cord-015369-72cjogxz 3317 11 targets target NNS cord-015369-72cjogxz 3317 12 to to TO cord-015369-72cjogxz 3317 13 prevent prevent VB cord-015369-72cjogxz 3317 14 migration migration NN cord-015369-72cjogxz 3317 15 of of IN cord-015369-72cjogxz 3317 16 gastric gastric JJ cord-015369-72cjogxz 3317 17 carcinoma carcinoma NN cord-015369-72cjogxz 3317 18 cells cell NNS cord-015369-72cjogxz 3317 19 into into IN cord-015369-72cjogxz 3317 20 the the DT cord-015369-72cjogxz 3317 21 peritoneum peritoneum NN cord-015369-72cjogxz 3317 22 generating generate VBG cord-015369-72cjogxz 3317 23 peritoneal peritoneal JJ cord-015369-72cjogxz 3317 24 carcinomatosis carcinomatosis NN cord-015369-72cjogxz 3317 25 . . . cord-015369-72cjogxz 3318 1 Here here RB cord-015369-72cjogxz 3318 2 , , , cord-015369-72cjogxz 3318 3 we -PRON- PRP cord-015369-72cjogxz 3318 4 investigated investigate VBD cord-015369-72cjogxz 3318 5 the the DT cord-015369-72cjogxz 3318 6 expression expression NN cord-015369-72cjogxz 3318 7 of of IN cord-015369-72cjogxz 3318 8 Dkk-3 Dkk-3 NNP cord-015369-72cjogxz 3318 9 protein protein NN cord-015369-72cjogxz 3318 10 in in IN cord-015369-72cjogxz 3318 11 gastric gastric JJ cord-015369-72cjogxz 3318 12 cancer cancer NN cord-015369-72cjogxz 3318 13 and and CC cord-015369-72cjogxz 3318 14 its -PRON- PRP$ cord-015369-72cjogxz 3318 15 potential potential JJ cord-015369-72cjogxz 3318 16 value value NN cord-015369-72cjogxz 3318 17 as as IN cord-015369-72cjogxz 3318 18 a a DT cord-015369-72cjogxz 3318 19 prognostic prognostic JJ cord-015369-72cjogxz 3318 20 marker marker NN cord-015369-72cjogxz 3318 21 . . . cord-015369-72cjogxz 3319 1 Methods method NNS cord-015369-72cjogxz 3319 2 . . . cord-015369-72cjogxz 3320 1 Dkk-3 Dkk-3 NNP cord-015369-72cjogxz 3320 2 expression expression NN cord-015369-72cjogxz 3320 3 was be VBD cord-015369-72cjogxz 3320 4 analyzed analyze VBN cord-015369-72cjogxz 3320 5 by by IN cord-015369-72cjogxz 3320 6 immunohistochemistry immunohistochemistry NN cord-015369-72cjogxz 3320 7 in in IN cord-015369-72cjogxz 3320 8 136 136 CD cord-015369-72cjogxz 3320 9 tumour tumour NN cord-015369-72cjogxz 3320 10 samples sample NNS cord-015369-72cjogxz 3320 11 and and CC cord-015369-72cjogxz 3320 12 was be VBD cord-015369-72cjogxz 3320 13 correlated correlate VBN cord-015369-72cjogxz 3320 14 with with IN cord-015369-72cjogxz 3320 15 microvessel microvessel NNP cord-015369-72cjogxz 3320 16 density density NN cord-015369-72cjogxz 3320 17 ( ( -LRB- cord-015369-72cjogxz 3320 18 MVD MVD NNP cord-015369-72cjogxz 3320 19 ) ) -RRB- cord-015369-72cjogxz 3320 20 , , , cord-015369-72cjogxz 3320 21 tumor tumor NN cord-015369-72cjogxz 3320 22 stage stage NN cord-015369-72cjogxz 3320 23 and and CC cord-015369-72cjogxz 3320 24 grading grading NN cord-015369-72cjogxz 3320 25 , , , cord-015369-72cjogxz 3320 26 as as RB cord-015369-72cjogxz 3320 27 well well RB cord-015369-72cjogxz 3320 28 as as IN cord-015369-72cjogxz 3320 29 the the DT cord-015369-72cjogxz 3320 30 clinical clinical JJ cord-015369-72cjogxz 3320 31 outcome outcome NN cord-015369-72cjogxz 3320 32 of of IN cord-015369-72cjogxz 3320 33 the the DT cord-015369-72cjogxz 3320 34 patients patient NNS cord-015369-72cjogxz 3320 35 . . . cord-015369-72cjogxz 3321 1 Results result NNS cord-015369-72cjogxz 3321 2 . . . cord-015369-72cjogxz 3322 1 Dkk-3 Dkk-3 NNP cord-015369-72cjogxz 3322 2 expression expression NN cord-015369-72cjogxz 3322 3 was be VBD cord-015369-72cjogxz 3322 4 detected detect VBN cord-015369-72cjogxz 3322 5 in in IN cord-015369-72cjogxz 3322 6 endothelial endothelial JJ cord-015369-72cjogxz 3322 7 cells cell NNS cord-015369-72cjogxz 3322 8 of of IN cord-015369-72cjogxz 3322 9 the the DT cord-015369-72cjogxz 3322 10 tumour tumour NN cord-015369-72cjogxz 3322 11 vessels vessel NNS cord-015369-72cjogxz 3322 12 but but CC cord-015369-72cjogxz 3322 13 not not RB cord-015369-72cjogxz 3322 14 in in IN cord-015369-72cjogxz 3322 15 normal normal JJ cord-015369-72cjogxz 3322 16 vessels vessel NNS cord-015369-72cjogxz 3322 17 in in IN cord-015369-72cjogxz 3322 18 129/136 129/136 CD cord-015369-72cjogxz 3322 19 ( ( -LRB- cord-015369-72cjogxz 3322 20 94.9 94.9 CD cord-015369-72cjogxz 3322 21 % % NN cord-015369-72cjogxz 3322 22 ) ) -RRB- cord-015369-72cjogxz 3322 23 and and CC cord-015369-72cjogxz 3322 24 in in IN cord-015369-72cjogxz 3322 25 tumor tumor NN cord-015369-72cjogxz 3322 26 cells cell NNS cord-015369-72cjogxz 3322 27 in in IN cord-015369-72cjogxz 3322 28 85/136 85/136 CD cord-015369-72cjogxz 3322 29 ( ( -LRB- cord-015369-72cjogxz 3322 30 62.5 62.5 CD cord-015369-72cjogxz 3322 31 % % NN cord-015369-72cjogxz 3322 32 ) ) -RRB- cord-015369-72cjogxz 3322 33 respectively respectively RB cord-015369-72cjogxz 3322 34 . . . cord-015369-72cjogxz 3323 1 MVD MVD NNP cord-015369-72cjogxz 3323 2 was be VBD cord-015369-72cjogxz 3323 3 high high JJ cord-015369-72cjogxz 3323 4 and and CC cord-015369-72cjogxz 3323 5 low low JJ cord-015369-72cjogxz 3323 6 in in IN cord-015369-72cjogxz 3323 7 57 57 CD cord-015369-72cjogxz 3323 8 ( ( -LRB- cord-015369-72cjogxz 3323 9 42.9 42.9 CD cord-015369-72cjogxz 3323 10 % % NN cord-015369-72cjogxz 3323 11 ) ) -RRB- cord-015369-72cjogxz 3323 12 and and CC cord-015369-72cjogxz 3323 13 76 76 CD cord-015369-72cjogxz 3323 14 ( ( -LRB- cord-015369-72cjogxz 3323 15 57.1 57.1 CD cord-015369-72cjogxz 3323 16 % % NN cord-015369-72cjogxz 3323 17 ) ) -RRB- cord-015369-72cjogxz 3323 18 specimens specimen NNS cord-015369-72cjogxz 3323 19 . . . cord-015369-72cjogxz 3324 1 In in IN cord-015369-72cjogxz 3324 2 tumor tumor NN cord-015369-72cjogxz 3324 3 cells cell NNS cord-015369-72cjogxz 3324 4 , , , cord-015369-72cjogxz 3324 5 overexpression overexpression NN cord-015369-72cjogxz 3324 6 of of IN cord-015369-72cjogxz 3324 7 Dkk-3 Dkk-3 NNP cord-015369-72cjogxz 3324 8 was be VBD cord-015369-72cjogxz 3324 9 found find VBN cord-015369-72cjogxz 3324 10 in in IN cord-015369-72cjogxz 3324 11 41 41 CD cord-015369-72cjogxz 3324 12 ( ( -LRB- cord-015369-72cjogxz 3324 13 30.1 30.1 CD cord-015369-72cjogxz 3324 14 % % NN cord-015369-72cjogxz 3324 15 ) ) -RRB- cord-015369-72cjogxz 3324 16 and and CC cord-015369-72cjogxz 3324 17 was be VBD cord-015369-72cjogxz 3324 18 correlated correlate VBN cord-015369-72cjogxz 3324 19 significantly significantly RB cord-015369-72cjogxz 3324 20 to to IN cord-015369-72cjogxz 3324 21 pT pt JJ cord-015369-72cjogxz 3324 22 - - HYPH cord-015369-72cjogxz 3324 23 stage stage NN cord-015369-72cjogxz 3324 24 ( ( -LRB- cord-015369-72cjogxz 3324 25 p p NN cord-015369-72cjogxz 3324 26 < < XX cord-015369-72cjogxz 3324 27 0.05 0.05 CD cord-015369-72cjogxz 3324 28 ) ) -RRB- cord-015369-72cjogxz 3324 29 and and CC cord-015369-72cjogxz 3324 30 UICC UICC NNP cord-015369-72cjogxz 3324 31 stage stage NN cord-015369-72cjogxz 3324 32 ( ( -LRB- cord-015369-72cjogxz 3324 33 p p NN cord-015369-72cjogxz 3324 34 < < XX cord-015369-72cjogxz 3324 35 0.05 0.05 CD cord-015369-72cjogxz 3324 36 ) ) -RRB- cord-015369-72cjogxz 3324 37 . . . cord-015369-72cjogxz 3325 1 Survival survival NN cord-015369-72cjogxz 3325 2 analysis analysis NN cord-015369-72cjogxz 3325 3 regarding regard VBG cord-015369-72cjogxz 3325 4 Dkk-3 Dkk-3 NNP cord-015369-72cjogxz 3325 5 expression expression NN cord-015369-72cjogxz 3325 6 in in IN cord-015369-72cjogxz 3325 7 tumor tumor NN cord-015369-72cjogxz 3325 8 endothelial endothelial JJ cord-015369-72cjogxz 3325 9 cells cell NNS cord-015369-72cjogxz 3325 10 showed show VBD cord-015369-72cjogxz 3325 11 that that IN cord-015369-72cjogxz 3325 12 Dkk-3 Dkk-3 NNP cord-015369-72cjogxz 3325 13 is be VBZ cord-015369-72cjogxz 3325 14 an an DT cord-015369-72cjogxz 3325 15 independent independent JJ cord-015369-72cjogxz 3325 16 predictor predictor NN cord-015369-72cjogxz 3325 17 of of IN cord-015369-72cjogxz 3325 18 disease disease NN cord-015369-72cjogxz 3325 19 - - HYPH cord-015369-72cjogxz 3325 20 free free JJ cord-015369-72cjogxz 3325 21 survival survival NN cord-015369-72cjogxz 3325 22 ( ( -LRB- cord-015369-72cjogxz 3325 23 p p NN cord-015369-72cjogxz 3325 24 < < XX cord-015369-72cjogxz 3325 25 0.05 0.05 CD cord-015369-72cjogxz 3325 26 ) ) -RRB- cord-015369-72cjogxz 3325 27 Conclusions conclusion NNS cord-015369-72cjogxz 3325 28 . . . cord-015369-72cjogxz 3326 1 Dkk-3 Dkk-3 NNP cord-015369-72cjogxz 3326 2 expression expression NN cord-015369-72cjogxz 3326 3 in in IN cord-015369-72cjogxz 3326 4 tumor tumor NN cord-015369-72cjogxz 3326 5 vessels vessel NNS cord-015369-72cjogxz 3326 6 of of IN cord-015369-72cjogxz 3326 7 patients patient NNS cord-015369-72cjogxz 3326 8 with with IN cord-015369-72cjogxz 3326 9 gastric gastric JJ cord-015369-72cjogxz 3326 10 cancer cancer NN cord-015369-72cjogxz 3326 11 identifies identify VBZ cord-015369-72cjogxz 3326 12 a a DT cord-015369-72cjogxz 3326 13 population population NN cord-015369-72cjogxz 3326 14 of of IN cord-015369-72cjogxz 3326 15 patients patient NNS cord-015369-72cjogxz 3326 16 with with IN cord-015369-72cjogxz 3326 17 relatively relatively RB cord-015369-72cjogxz 3326 18 favorable favorable JJ cord-015369-72cjogxz 3326 19 prognosis prognosis NN cord-015369-72cjogxz 3326 20 . . . cord-015369-72cjogxz 3327 1 Methodik Methodik NNP cord-015369-72cjogxz 3327 2 . . . cord-015369-72cjogxz 3328 1 Bei Bei NNP cord-015369-72cjogxz 3328 2 nach nach NNP cord-015369-72cjogxz 3328 3 den den NNP cord-015369-72cjogxz 3328 4 international international NNP cord-015369-72cjogxz 3328 5 anerkannten anerkannten VBD cord-015369-72cjogxz 3328 6 Kriterien Kriterien NNP cord-015369-72cjogxz 3328 7 ( ( -LRB- cord-015369-72cjogxz 3328 8 IGCLC IGCLC NNP cord-015369-72cjogxz 3328 9 -International -International NNP cord-015369-72cjogxz 3328 10 Gastric Gastric NNP cord-015369-72cjogxz 3328 11 Cancer Cancer NNP cord-015369-72cjogxz 3328 12 Linkage Linkage NNP cord-015369-72cjogxz 3328 13 Konsortium Konsortium NNP cord-015369-72cjogxz 3328 14 ) ) -RRB- cord-015369-72cjogxz 3329 1 gegebenen gegebenen NNP cord-015369-72cjogxz 3330 1 Verdacht Verdacht NNP cord-015369-72cjogxz 3330 2 auf auf NNP cord-015369-72cjogxz 3330 3 ein ein NNP cord-015369-72cjogxz 3330 4 hereditäres hereditäre NNS cord-015369-72cjogxz 3330 5 diffuses diffuse VBZ cord-015369-72cjogxz 3330 6 Magenkarzinomsyndrom Magenkarzinomsyndrom NNP cord-015369-72cjogxz 3330 7 wurde wurde NNP cord-015369-72cjogxz 3330 8 eine eine NNP cord-015369-72cjogxz 3330 9 E E NNP cord-015369-72cjogxz 3330 10 - - HYPH cord-015369-72cjogxz 3330 11 Cadherin Cadherin NNP cord-015369-72cjogxz 3330 12 - - HYPH cord-015369-72cjogxz 3330 13 Mutationsbestimmung Mutationsbestimmung NNP cord-015369-72cjogxz 3330 14 ( ( -LRB- cord-015369-72cjogxz 3330 15 CDH1 CDH1 NNP cord-015369-72cjogxz 3330 16 ) ) -RRB- cord-015369-72cjogxz 3331 1 erstgradiger erstgradiger NNP cord-015369-72cjogxz 3331 2 Familienmitglieder Familienmitglieder NNP cord-015369-72cjogxz 3331 3 durchgeführt durchgeführt NN cord-015369-72cjogxz 3331 4 . . . cord-015369-72cjogxz 3332 1 Acht Acht NNP cord-015369-72cjogxz 3332 2 von von NNP cord-015369-72cjogxz 3332 3 neun neun NNP cord-015369-72cjogxz 3333 1 untersuchten untersuchten NNP cord-015369-72cjogxz 3333 2 Familienmitgliedern Familienmitgliedern NNP cord-015369-72cjogxz 3333 3 waren waren VBD cord-015369-72cjogxz 3333 4 positiv positiv JJ cord-015369-72cjogxz 3333 5 für für NNS cord-015369-72cjogxz 3333 6 die die VBP cord-015369-72cjogxz 3333 7 CDH1 CDH1 NNP cord-015369-72cjogxz 3333 8 Keimbahnmutation Keimbahnmutation NNP cord-015369-72cjogxz 3333 9 . . . cord-015369-72cjogxz 3334 1 In in IN cord-015369-72cjogxz 3334 2 allen allen NNP cord-015369-72cjogxz 3334 3 Fällen Fällen NNP cord-015369-72cjogxz 3334 4 konnte konnte NNP cord-015369-72cjogxz 3334 5 präoperativ präoperativ NN cord-015369-72cjogxz 3334 6 das das NNP cord-015369-72cjogxz 3334 7 Vorliegen Vorliegen NNP cord-015369-72cjogxz 3334 8 eines eines NNP cord-015369-72cjogxz 3334 9 Karzinoms Karzinoms NNP cord-015369-72cjogxz 3334 10 durch durch NNP cord-015369-72cjogxz 3334 11 eine eine NNP cord-015369-72cjogxz 3334 12 ausgiebige ausgiebige NNP cord-015369-72cjogxz 3334 13 Endoskopie Endoskopie NNP cord-015369-72cjogxz 3334 14 ausgeschlossen ausgeschlossen VBD cord-015369-72cjogxz 3334 15 werden werden NNP cord-015369-72cjogxz 3334 16 . . . cord-015369-72cjogxz 3335 1 Fünf Fünf NNP cord-015369-72cjogxz 3335 2 Träger Träger NNP cord-015369-72cjogxz 3335 3 der der NNP cord-015369-72cjogxz 3335 4 Mutation Mutation NNP cord-015369-72cjogxz 3335 5 entschlossen entschlossen NNP cord-015369-72cjogxz 3335 6 sich sich NNP cord-015369-72cjogxz 3335 7 nach nach NNP cord-015369-72cjogxz 3335 8 einer einer NNP cord-015369-72cjogxz 3335 9 ausführlichen ausführlichen NNP cord-015369-72cjogxz 3335 10 , , , cord-015369-72cjogxz 3335 11 chirurgischen chirurgischen NNP cord-015369-72cjogxz 3335 12 Beratung Beratung NNP cord-015369-72cjogxz 3335 13 zur zur NNP cord-015369-72cjogxz 3335 14 prophylaktischen prophylaktischen NNP cord-015369-72cjogxz 3335 15 Operation Operation NNP cord-015369-72cjogxz 3335 16 . . . cord-015369-72cjogxz 3336 1 In in IN cord-015369-72cjogxz 3336 2 einem einem NNP cord-015369-72cjogxz 3336 3 Fall Fall NNP cord-015369-72cjogxz 3336 4 wurde wurde NNP cord-015369-72cjogxz 3336 5 präoperativ präoperativ NNP cord-015369-72cjogxz 3336 6 eine eine NNP cord-015369-72cjogxz 3337 1 Mukosektomie Mukosektomie NNP cord-015369-72cjogxz 3337 2 einer einer NNP cord-015369-72cjogxz 3337 3 ektopen ektopen JJ cord-015369-72cjogxz 3337 4 Magenschleimhaut Magenschleimhaut NNP cord-015369-72cjogxz 3338 1 i -PRON- PRP cord-015369-72cjogxz 3338 2 m be VBP cord-015369-72cjogxz 3338 3 Oesophagus Oesophagus NNP cord-015369-72cjogxz 3338 4 durchgeführt durchgeführt NN cord-015369-72cjogxz 3338 5 . . . cord-015369-72cjogxz 3339 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 3339 2 . . . cord-015369-72cjogxz 3340 1 Aufgrund Aufgrund NNP cord-015369-72cjogxz 3340 2 der der VBD cord-015369-72cjogxz 3340 3 Indikationsstellung Indikationsstellung NNP cord-015369-72cjogxz 3340 4 mit mit NNP cord-015369-72cjogxz 3340 5 Verzicht Verzicht NNP cord-015369-72cjogxz 3340 6 auf auf NNP cord-015369-72cjogxz 3341 1 eine eine NNP cord-015369-72cjogxz 3341 2 Lymphadenektomie Lymphadenektomie NNP cord-015369-72cjogxz 3341 3 entlang entlang NNP cord-015369-72cjogxz 3341 4 der der NNP cord-015369-72cjogxz 3341 5 Gefäße Gefäße NNP cord-015369-72cjogxz 3341 6 des des NNP cord-015369-72cjogxz 3341 7 Trunkus Trunkus NNP cord-015369-72cjogxz 3341 8 coeliacus coeliacus NN cord-015369-72cjogxz 3342 1 wurde wurde NNP cord-015369-72cjogxz 3342 2 die die VB cord-015369-72cjogxz 3343 1 Gastrektomie Gastrektomie NNP cord-015369-72cjogxz 3343 2 mit mit NNP cord-015369-72cjogxz 3343 3 LK LK NNP cord-015369-72cjogxz 3343 4 - - HYPH cord-015369-72cjogxz 3343 5 Dissektion Dissektion NNP cord-015369-72cjogxz 3344 1 D-1 D-1 NNP cord-015369-72cjogxz 3344 2 in in IN cord-015369-72cjogxz 3344 3 laparoskopische laparoskopische NN cord-015369-72cjogxz 3344 4 Technik Technik NNP cord-015369-72cjogxz 3344 5 durchgefü durchgefü NNP cord-015369-72cjogxz 3344 6 hrt hrt NNP cord-015369-72cjogxz 3344 7 . . . cord-015369-72cjogxz 3345 1 In in IN cord-015369-72cjogxz 3345 2 systemischer systemischer NNP cord-015369-72cjogxz 3345 3 Aufarbeitung Aufarbeitung NNP cord-015369-72cjogxz 3345 4 des des FW cord-015369-72cjogxz 3345 5 ganzen ganzen NNP cord-015369-72cjogxz 3345 6 Magens Magens NNP cord-015369-72cjogxz 3345 7 konnte konnte NNP cord-015369-72cjogxz 3345 8 in in IN cord-015369-72cjogxz 3345 9 allen allen NNP cord-015369-72cjogxz 3345 10 Fällen Fällen NNP cord-015369-72cjogxz 3345 11 ein ein NNP cord-015369-72cjogxz 3345 12 intramukosales intramukosales NNP cord-015369-72cjogxz 3345 13 monozellulär monozellulär NNP cord-015369-72cjogxz 3345 14 verschleimendes verschleimendes NNP cord-015369-72cjogxz 3345 15 Magenkarzinom Magenkarzinom NNP cord-015369-72cjogxz 3345 16 nachgewiesen nachgewiesen NNP cord-015369-72cjogxz 3345 17 werden werden NNP cord-015369-72cjogxz 3345 18 . . . cord-015369-72cjogxz 3346 1 Eine Eine NNP cord-015369-72cjogxz 3346 2 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 3346 3 - - HYPH cord-015369-72cjogxz 3346 4 oder oder NNP cord-015369-72cjogxz 3346 5 Gefäßinvasion Gefäßinvasion NNP cord-015369-72cjogxz 3346 6 konnte konnte NNP cord-015369-72cjogxz 3346 7 nicht nicht NNP cord-015369-72cjogxz 3346 8 nachgewiesen nachgewiesen NNP cord-015369-72cjogxz 3346 9 werden werden NNP cord-015369-72cjogxz 3346 10 . . . cord-015369-72cjogxz 3347 1 Es Es NNP cord-015369-72cjogxz 3347 2 konnten konnten NNP cord-015369-72cjogxz 3347 3 zwischen zwischen NNP cord-015369-72cjogxz 3347 4 14 14 CD cord-015369-72cjogxz 3347 5 bis bis CD cord-015369-72cjogxz 3347 6 28 28 CD cord-015369-72cjogxz 3348 1 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 3348 2 untersucht untersucht NN cord-015369-72cjogxz 3348 3 werden werden NNP cord-015369-72cjogxz 3349 1 ( ( -LRB- cord-015369-72cjogxz 3349 2 i -PRON- PRP cord-015369-72cjogxz 3349 3 m be VBP cord-015369-72cjogxz 3349 4 Durchschnitt Durchschnitt NNP cord-015369-72cjogxz 3349 5 22 22 CD cord-015369-72cjogxz 3349 6 untersuchte untersuchte NN cord-015369-72cjogxz 3349 7 LK LK NNP cord-015369-72cjogxz 3349 8 ) ) -RRB- cord-015369-72cjogxz 3349 9 . . . cord-015369-72cjogxz 3350 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 3350 2 . . . cord-015369-72cjogxz 3351 1 Die die VB cord-015369-72cjogxz 3351 2 Gastrektomie Gastrektomie NNP cord-015369-72cjogxz 3351 3 in in IN cord-015369-72cjogxz 3351 4 laparoskopischer laparoskopischer NN cord-015369-72cjogxz 3352 1 Technik Technik NNP cord-015369-72cjogxz 3352 2 ist ist NNP cord-015369-72cjogxz 3353 1 ein ein NNP cord-015369-72cjogxz 3353 2 onkologisch onkologisch NNP cord-015369-72cjogxz 3353 3 korrektes korrektes NNP cord-015369-72cjogxz 3353 4 , , , cord-015369-72cjogxz 3353 5 sicheres sicheres NNPS cord-015369-72cjogxz 3353 6 und und IN cord-015369-72cjogxz 3353 7 für für JJ cord-015369-72cjogxz 3353 8 diese diese NNP cord-015369-72cjogxz 3353 9 Indikation Indikation NNP cord-015369-72cjogxz 3353 10 gutes gutes NNP cord-015369-72cjogxz 3353 11 Verfahren Verfahren NNP cord-015369-72cjogxz 3353 12 . . . cord-015369-72cjogxz 3354 1 Wir Wir NNP cord-015369-72cjogxz 3354 2 sahen sahen NNP cord-015369-72cjogxz 3355 1 bis bis NNP cord-015369-72cjogxz 3355 2 auf auf NNP cord-015369-72cjogxz 3356 1 eine eine NNP cord-015369-72cjogxz 3356 2 Wundheilungsstörung Wundheilungsstörung NNP cord-015369-72cjogxz 3356 3 an an DT cord-015369-72cjogxz 3356 4 einer einer NN cord-015369-72cjogxz 3357 1 Trockareinstichstelle Trockareinstichstelle NNP cord-015369-72cjogxz 3357 2 keine keine NNP cord-015369-72cjogxz 3357 3 chirurgischen chirurgischen FW cord-015369-72cjogxz 3357 4 Probleme Probleme NNP cord-015369-72cjogxz 3357 5 . . . cord-015369-72cjogxz 3358 1 Alle Alle NNP cord-015369-72cjogxz 3358 2 Vorteile Vorteile NNP cord-015369-72cjogxz 3358 3 der der NN cord-015369-72cjogxz 3358 4 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 3359 1 Technik Technik NNP cord-015369-72cjogxz 3359 2 konnten konnten NNP cord-015369-72cjogxz 3359 3 umgesetzt umgesetzt VBD cord-015369-72cjogxz 3359 4 werden werden NNP cord-015369-72cjogxz 3359 5 . . . cord-015369-72cjogxz 3360 1 Background background NN cord-015369-72cjogxz 3360 2 . . . cord-015369-72cjogxz 3361 1 Incisional Incisional NNP cord-015369-72cjogxz 3361 2 trauma trauma NN cord-015369-72cjogxz 3361 3 is be VBZ cord-015369-72cjogxz 3361 4 major major JJ cord-015369-72cjogxz 3361 5 factor factor NN cord-015369-72cjogxz 3361 6 contributing contribute VBG cord-015369-72cjogxz 3361 7 to to IN cord-015369-72cjogxz 3361 8 perioperative perioperative JJ cord-015369-72cjogxz 3361 9 morbidity morbidity NN cord-015369-72cjogxz 3361 10 and and CC cord-015369-72cjogxz 3361 11 mortality mortality NN cord-015369-72cjogxz 3361 12 . . . cord-015369-72cjogxz 3362 1 Cosmesis Cosmesis NNP cord-015369-72cjogxz 3362 2 and and CC cord-015369-72cjogxz 3362 3 body body NN cord-015369-72cjogxz 3362 4 awareness awareness NN cord-015369-72cjogxz 3362 5 also also RB cord-015369-72cjogxz 3362 6 play play VBP cord-015369-72cjogxz 3362 7 an an DT cord-015369-72cjogxz 3362 8 increasing increase VBG cord-015369-72cjogxz 3362 9 role role NN cord-015369-72cjogxz 3362 10 in in IN cord-015369-72cjogxz 3362 11 patients patient NNS cord-015369-72cjogxz 3362 12 ' ' POS cord-015369-72cjogxz 3362 13 acceptance acceptance NN cord-015369-72cjogxz 3362 14 of of IN cord-015369-72cjogxz 3362 15 cardiac cardiac JJ cord-015369-72cjogxz 3362 16 surgery surgery NN cord-015369-72cjogxz 3362 17 . . . cord-015369-72cjogxz 3363 1 During during IN cord-015369-72cjogxz 3363 2 the the DT cord-015369-72cjogxz 3363 3 last last JJ cord-015369-72cjogxz 3363 4 years year NNS cord-015369-72cjogxz 3363 5 it -PRON- PRP cord-015369-72cjogxz 3363 6 was be VBD cord-015369-72cjogxz 3363 7 our -PRON- PRP$ cord-015369-72cjogxz 3363 8 effort effort NN cord-015369-72cjogxz 3363 9 to to TO cord-015369-72cjogxz 3363 10 increase increase VB cord-015369-72cjogxz 3363 11 the the DT cord-015369-72cjogxz 3363 12 percentage percentage NN cord-015369-72cjogxz 3363 13 of of IN cord-015369-72cjogxz 3363 14 minimally minimally RB cord-015369-72cjogxz 3363 15 invasive invasive JJ cord-015369-72cjogxz 3363 16 operations operation NNS cord-015369-72cjogxz 3363 17 . . . cord-015369-72cjogxz 3364 1 Methods method NNS cord-015369-72cjogxz 3364 2 . . . cord-015369-72cjogxz 3365 1 Cardiac cardiac JJ cord-015369-72cjogxz 3365 2 surgical surgical JJ cord-015369-72cjogxz 3365 3 operations operation NNS cord-015369-72cjogxz 3365 4 of of IN cord-015369-72cjogxz 3365 5 the the DT cord-015369-72cjogxz 3365 6 last last JJ cord-015369-72cjogxz 3365 7 3 3 CD cord-015369-72cjogxz 3365 8 years year NNS cord-015369-72cjogxz 3365 9 were be VBD cord-015369-72cjogxz 3365 10 evaluated evaluate VBN cord-015369-72cjogxz 3365 11 regarding regard VBG cord-015369-72cjogxz 3365 12 conventional conventional JJ cord-015369-72cjogxz 3365 13 ( ( -LRB- cord-015369-72cjogxz 3365 14 median median JJ cord-015369-72cjogxz 3365 15 sternotomy sternotomy NN cord-015369-72cjogxz 3365 16 ) ) -RRB- cord-015369-72cjogxz 3365 17 approach approach NN cord-015369-72cjogxz 3365 18 and and CC cord-015369-72cjogxz 3365 19 minithoracotomy minithoracotomy VBP cord-015369-72cjogxz 3365 20 or or CC cord-015369-72cjogxz 3365 21 total total JJ cord-015369-72cjogxz 3365 22 endoscopic endoscopic JJ cord-015369-72cjogxz 3365 23 surgery surgery NN cord-015369-72cjogxz 3365 24 . . . cord-015369-72cjogxz 3366 1 Indications indication NNS cord-015369-72cjogxz 3366 2 for for IN cord-015369-72cjogxz 3366 3 either either DT cord-015369-72cjogxz 3366 4 procedure procedure NN cord-015369-72cjogxz 3366 5 were be VBD cord-015369-72cjogxz 3366 6 identified identify VBN cord-015369-72cjogxz 3366 7 . . . cord-015369-72cjogxz 3367 1 Results result NNS cord-015369-72cjogxz 3367 2 Indications indication NNS cord-015369-72cjogxz 3367 3 were be VBD cord-015369-72cjogxz 3367 4 extended extend VBN cord-015369-72cjogxz 3367 5 to to IN cord-015369-72cjogxz 3367 6 complex complex VB cord-015369-72cjogxz 3367 7 valvular valvular JJ cord-015369-72cjogxz 3367 8 , , , cord-015369-72cjogxz 3367 9 bivalvular bivalvular JJ cord-015369-72cjogxz 3367 10 and and CC cord-015369-72cjogxz 3367 11 other other JJ cord-015369-72cjogxz 3367 12 combined combined JJ cord-015369-72cjogxz 3367 13 procedures procedure NNS cord-015369-72cjogxz 3367 14 . . . cord-015369-72cjogxz 3368 1 Major major JJ cord-015369-72cjogxz 3368 2 contraindications contraindication NNS cord-015369-72cjogxz 3368 3 are be VBP cord-015369-72cjogxz 3368 4 severe severe JJ cord-015369-72cjogxz 3368 5 calcifications calcification NNS cord-015369-72cjogxz 3368 6 and and CC cord-015369-72cjogxz 3368 7 aortic aortic JJ cord-015369-72cjogxz 3368 8 dilatation dilatation NN cord-015369-72cjogxz 3368 9 . . . cord-015369-72cjogxz 3369 1 TECAB TECAB NNP cord-015369-72cjogxz 3369 2 could could MD cord-015369-72cjogxz 3369 3 be be VB cord-015369-72cjogxz 3369 4 performed perform VBN cord-015369-72cjogxz 3369 5 for for IN cord-015369-72cjogxz 3369 6 single single JJ cord-015369-72cjogxz 3369 7 and and CC cord-015369-72cjogxz 3369 8 double double JJ cord-015369-72cjogxz 3369 9 vessel vessel NN cord-015369-72cjogxz 3369 10 revascularisation revascularisation NN cord-015369-72cjogxz 3369 11 as as RB cord-015369-72cjogxz 3369 12 well well RB cord-015369-72cjogxz 3369 13 as as IN cord-015369-72cjogxz 3369 14 hybrid hybrid JJ cord-015369-72cjogxz 3369 15 procedures procedure NNS cord-015369-72cjogxz 3369 16 including include VBG cord-015369-72cjogxz 3369 17 PCI pci NN cord-015369-72cjogxz 3369 18 . . . cord-015369-72cjogxz 3370 1 Conclusions conclusion NNS cord-015369-72cjogxz 3370 2 . . . cord-015369-72cjogxz 3371 1 An an DT cord-015369-72cjogxz 3371 2 increasing increase VBG cord-015369-72cjogxz 3371 3 percentage percentage NN cord-015369-72cjogxz 3371 4 of of IN cord-015369-72cjogxz 3371 5 cardiac cardiac JJ cord-015369-72cjogxz 3371 6 surgical surgical JJ cord-015369-72cjogxz 3371 7 operations operation NNS cord-015369-72cjogxz 3371 8 can can MD cord-015369-72cjogxz 3371 9 be be VB cord-015369-72cjogxz 3371 10 performed perform VBN cord-015369-72cjogxz 3371 11 minimally minimally RB cord-015369-72cjogxz 3371 12 invasive invasive JJ cord-015369-72cjogxz 3371 13 . . . cord-015369-72cjogxz 3372 1 However however RB cord-015369-72cjogxz 3372 2 this this DT cord-015369-72cjogxz 3372 3 evolution evolution NN cord-015369-72cjogxz 3372 4 has have VBZ cord-015369-72cjogxz 3372 5 still still RB cord-015369-72cjogxz 3372 6 to to TO cord-015369-72cjogxz 3372 7 be be VB cord-015369-72cjogxz 3372 8 more more RBR cord-015369-72cjogxz 3372 9 widespread widespread JJ cord-015369-72cjogxz 3372 10 especially especially RB cord-015369-72cjogxz 3372 11 in in IN cord-015369-72cjogxz 3372 12 the the DT cord-015369-72cjogxz 3372 13 era era NN cord-015369-72cjogxz 3372 14 of of IN cord-015369-72cjogxz 3372 15 interventional interventional JJ cord-015369-72cjogxz 3372 16 valve valve NN cord-015369-72cjogxz 3372 17 procedures procedure NNS cord-015369-72cjogxz 3372 18 . . . cord-015369-72cjogxz 3373 1 The the DT cord-015369-72cjogxz 3373 2 heartport heartport NN cord-015369-72cjogxz 3373 3 access access NN cord-015369-72cjogxz 3373 4 for for IN cord-015369-72cjogxz 3373 5 increased increased JJ cord-015369-72cjogxz 3373 6 patient patient JJ cord-015369-72cjogxz 3373 7 mobility mobility NN cord-015369-72cjogxz 3373 8 and and CC cord-015369-72cjogxz 3373 9 satisfaction satisfaction NN cord-015369-72cjogxz 3373 10 T. T. NNP cord-015369-72cjogxz 3373 11 Fleck Fleck NNP cord-015369-72cjogxz 3373 12 , , , cord-015369-72cjogxz 3373 13 W. W. NNP cord-015369-72cjogxz 3373 14 Wisser Wisser NNP cord-015369-72cjogxz 3373 15 Median Median NNP cord-015369-72cjogxz 3373 16 sternotomy sternotomy NN cord-015369-72cjogxz 3373 17 is be VBZ cord-015369-72cjogxz 3373 18 the the DT cord-015369-72cjogxz 3373 19 gold gold NN cord-015369-72cjogxz 3373 20 standard standard NN cord-015369-72cjogxz 3373 21 in in IN cord-015369-72cjogxz 3373 22 cardiac cardiac JJ cord-015369-72cjogxz 3373 23 surgery surgery NN cord-015369-72cjogxz 3373 24 , , , cord-015369-72cjogxz 3373 25 as as IN cord-015369-72cjogxz 3373 26 it -PRON- PRP cord-015369-72cjogxz 3373 27 enables enable VBZ cord-015369-72cjogxz 3373 28 superior superior JJ cord-015369-72cjogxz 3373 29 exposure exposure NN cord-015369-72cjogxz 3373 30 for for IN cord-015369-72cjogxz 3373 31 nearly nearly RB cord-015369-72cjogxz 3373 32 all all DT cord-015369-72cjogxz 3373 33 surgical surgical JJ cord-015369-72cjogxz 3373 34 procedures procedure NNS cord-015369-72cjogxz 3373 35 . . . cord-015369-72cjogxz 3374 1 However however RB cord-015369-72cjogxz 3374 2 , , , cord-015369-72cjogxz 3374 3 there there EX cord-015369-72cjogxz 3374 4 are be VBP cord-015369-72cjogxz 3374 5 disadvantages disadvantage NNS cord-015369-72cjogxz 3374 6 , , , cord-015369-72cjogxz 3374 7 namely namely RB cord-015369-72cjogxz 3374 8 the the DT cord-015369-72cjogxz 3374 9 risk risk NN cord-015369-72cjogxz 3374 10 of of IN cord-015369-72cjogxz 3374 11 sternal sternal JJ cord-015369-72cjogxz 3374 12 dehiscence dehiscence NN cord-015369-72cjogxz 3374 13 with with IN cord-015369-72cjogxz 3374 14 or or CC cord-015369-72cjogxz 3374 15 without without IN cord-015369-72cjogxz 3374 16 infection infection NN cord-015369-72cjogxz 3374 17 with with IN cord-015369-72cjogxz 3374 18 an an DT cord-015369-72cjogxz 3374 19 incidence incidence NN cord-015369-72cjogxz 3374 20 of of IN cord-015369-72cjogxz 3374 21 3 3 CD cord-015369-72cjogxz 3374 22 - - SYM cord-015369-72cjogxz 3374 23 5 5 CD cord-015369-72cjogxz 3374 24 % % NN cord-015369-72cjogxz 3374 25 and and CC cord-015369-72cjogxz 3374 26 the the DT cord-015369-72cjogxz 3374 27 immobility immobility NN cord-015369-72cjogxz 3374 28 of of IN cord-015369-72cjogxz 3374 29 the the DT cord-015369-72cjogxz 3374 30 patient patient NN cord-015369-72cjogxz 3374 31 for for IN cord-015369-72cjogxz 3374 32 the the DT cord-015369-72cjogxz 3374 33 healing healing NN cord-015369-72cjogxz 3374 34 process process NN cord-015369-72cjogxz 3374 35 of of IN cord-015369-72cjogxz 3374 36 the the DT cord-015369-72cjogxz 3374 37 bone bone NN cord-015369-72cjogxz 3374 38 . . . cord-015369-72cjogxz 3375 1 Since since IN cord-015369-72cjogxz 3375 2 2005 2005 CD cord-015369-72cjogxz 3375 3 a a DT cord-015369-72cjogxz 3375 4 total total NN cord-015369-72cjogxz 3375 5 of of IN cord-015369-72cjogxz 3375 6 50 50 CD cord-015369-72cjogxz 3375 7 patients patient NNS cord-015369-72cjogxz 3375 8 ( ( -LRB- cord-015369-72cjogxz 3375 9 mean mean VB cord-015369-72cjogxz 3375 10 age age NN cord-015369-72cjogxz 3375 11 56 56 CD cord-015369-72cjogxz 3375 12 years year NNS cord-015369-72cjogxz 3375 13 ) ) -RRB- cord-015369-72cjogxz 3375 14 underwent undergo VBD cord-015369-72cjogxz 3375 15 cardiac cardiac JJ cord-015369-72cjogxz 3375 16 surgery surgery NN cord-015369-72cjogxz 3375 17 through through IN cord-015369-72cjogxz 3375 18 a a DT cord-015369-72cjogxz 3375 19 mini mini JJ cord-015369-72cjogxz 3375 20 right right JJ cord-015369-72cjogxz 3375 21 thoracotomy thoracotomy NN cord-015369-72cjogxz 3375 22 in in IN cord-015369-72cjogxz 3375 23 the the DT cord-015369-72cjogxz 3375 24 4 4 CD cord-015369-72cjogxz 3375 25 ICR ICR NNP cord-015369-72cjogxz 3375 26 without without IN cord-015369-72cjogxz 3375 27 rib rib NN cord-015369-72cjogxz 3375 28 spreading spreading NN cord-015369-72cjogxz 3375 29 . . . cord-015369-72cjogxz 3376 1 The the DT cord-015369-72cjogxz 3376 2 underlying underlie VBG cord-015369-72cjogxz 3376 3 pathology pathology NN cord-015369-72cjogxz 3376 4 was be VBD cord-015369-72cjogxz 3376 5 MVD MVD NNP cord-015369-72cjogxz 3376 6 n n NNP cord-015369-72cjogxz 3376 7 ¼ ¼ NNP cord-015369-72cjogxz 3376 8 38 38 CD cord-015369-72cjogxz 3376 9 , , , cord-015369-72cjogxz 3376 10 TVD TVD NNP cord-015369-72cjogxz 3376 11 n n NN cord-015369-72cjogxz 3376 12 ¼ ¼ NNP cord-015369-72cjogxz 3376 13 11 11 CD cord-015369-72cjogxz 3376 14 , , , cord-015369-72cjogxz 3376 15 ASD ASD NNP cord-015369-72cjogxz 3376 16 n n NNP cord-015369-72cjogxz 3376 17 ¼ ¼ NNP cord-015369-72cjogxz 3376 18 5 5 CD cord-015369-72cjogxz 3376 19 , , , cord-015369-72cjogxz 3376 20 Myxoma Myxoma NNP cord-015369-72cjogxz 3376 21 n n NNP cord-015369-72cjogxz 3376 22 ¼ ¼ NN cord-015369-72cjogxz 3376 23 1 1 CD cord-015369-72cjogxz 3377 1 ( ( -LRB- cord-015369-72cjogxz 3377 2 mean mean VB cord-015369-72cjogxz 3377 3 ES ES NNP cord-015369-72cjogxz 3377 4 5.3 5.3 CD cord-015369-72cjogxz 3377 5 ) ) -RRB- cord-015369-72cjogxz 3377 6 . . . cord-015369-72cjogxz 3378 1 CPB CPB NNP cord-015369-72cjogxz 3378 2 was be VBD cord-015369-72cjogxz 3378 3 established establish VBN cord-015369-72cjogxz 3378 4 through through IN cord-015369-72cjogxz 3378 5 a a DT cord-015369-72cjogxz 3378 6 2.5 2.5 CD cord-015369-72cjogxz 3378 7 cm cm NN cord-015369-72cjogxz 3378 8 incision incision NN cord-015369-72cjogxz 3378 9 in in IN cord-015369-72cjogxz 3378 10 the the DT cord-015369-72cjogxz 3378 11 right right JJ cord-015369-72cjogxz 3378 12 groin groin NN cord-015369-72cjogxz 3378 13 . . . cord-015369-72cjogxz 3379 1 The the DT cord-015369-72cjogxz 3379 2 aorta aorta NN cord-015369-72cjogxz 3379 3 was be VBD cord-015369-72cjogxz 3379 4 occluded occlude VBN cord-015369-72cjogxz 3379 5 with with IN cord-015369-72cjogxz 3379 6 an an DT cord-015369-72cjogxz 3379 7 endoballon endoballon NN cord-015369-72cjogxz 3379 8 . . . cord-015369-72cjogxz 3380 1 Exposure exposure NN cord-015369-72cjogxz 3380 2 was be VBD cord-015369-72cjogxz 3380 3 satisfactory satisfactory JJ cord-015369-72cjogxz 3380 4 in in IN cord-015369-72cjogxz 3380 5 all all DT cord-015369-72cjogxz 3380 6 patients patient NNS cord-015369-72cjogxz 3380 7 . . . cord-015369-72cjogxz 3381 1 Especially especially RB cord-015369-72cjogxz 3381 2 in in IN cord-015369-72cjogxz 3381 3 Redo redo JJ cord-015369-72cjogxz 3381 4 procedures procedure NNS cord-015369-72cjogxz 3381 5 ( ( -LRB- cord-015369-72cjogxz 3381 6 n n CC cord-015369-72cjogxz 3381 7 ¼ ¼ NNP cord-015369-72cjogxz 3381 8 6 6 CD cord-015369-72cjogxz 3381 9 ) ) -RRB- cord-015369-72cjogxz 3382 1 the the DT cord-015369-72cjogxz 3382 2 necessity necessity NN cord-015369-72cjogxz 3382 3 of of IN cord-015369-72cjogxz 3382 4 dissection dissection NN cord-015369-72cjogxz 3382 5 of of IN cord-015369-72cjogxz 3382 6 the the DT cord-015369-72cjogxz 3382 7 entire entire JJ cord-015369-72cjogxz 3382 8 heart heart NN cord-015369-72cjogxz 3382 9 was be VBD cord-015369-72cjogxz 3382 10 avoided avoid VBN cord-015369-72cjogxz 3382 11 and and CC cord-015369-72cjogxz 3382 12 this this DT cord-015369-72cjogxz 3382 13 reduced reduce VBD cord-015369-72cjogxz 3382 14 the the DT cord-015369-72cjogxz 3382 15 amount amount NN cord-015369-72cjogxz 3382 16 of of IN cord-015369-72cjogxz 3382 17 bleeding bleeding NN cord-015369-72cjogxz 3382 18 and and CC cord-015369-72cjogxz 3382 19 the the DT cord-015369-72cjogxz 3382 20 known know VBN cord-015369-72cjogxz 3382 21 risks risk NNS cord-015369-72cjogxz 3382 22 of of IN cord-015369-72cjogxz 3382 23 redo redo NN cord-015369-72cjogxz 3382 24 sternotomy sternotomy NN cord-015369-72cjogxz 3382 25 . . . cord-015369-72cjogxz 3383 1 The the DT cord-015369-72cjogxz 3383 2 indented indented JJ cord-015369-72cjogxz 3383 3 surgical surgical JJ cord-015369-72cjogxz 3383 4 procedures procedure NNS cord-015369-72cjogxz 3383 5 could could MD cord-015369-72cjogxz 3383 6 be be VB cord-015369-72cjogxz 3383 7 preformed preform VBN cord-015369-72cjogxz 3383 8 in in IN cord-015369-72cjogxz 3383 9 all all DT cord-015369-72cjogxz 3383 10 patients patient NNS cord-015369-72cjogxz 3383 11 : : : cord-015369-72cjogxz 3383 12 MVR MVR NNP cord-015369-72cjogxz 3383 13 n n NNP cord-015369-72cjogxz 3383 14 ¼ ¼ NNP cord-015369-72cjogxz 3383 15 38 38 CD cord-015369-72cjogxz 3383 16 , , , cord-015369-72cjogxz 3383 17 ASD ASD NNP cord-015369-72cjogxz 3383 18 closure closure NN cord-015369-72cjogxz 3383 19 n n NNP cord-015369-72cjogxz 3383 20 ¼ ¼ NNP cord-015369-72cjogxz 3383 21 5 5 CD cord-015369-72cjogxz 3383 22 , , , cord-015369-72cjogxz 3383 23 myxoma myxoma NNP cord-015369-72cjogxz 3383 24 resection resection NNP cord-015369-72cjogxz 3383 25 n n NNP cord-015369-72cjogxz 3383 26 ¼ ¼ NNP cord-015369-72cjogxz 3383 27 1 1 CD cord-015369-72cjogxz 3383 28 , , , cord-015369-72cjogxz 3383 29 TVR TVR NNP cord-015369-72cjogxz 3383 30 n n NNP cord-015369-72cjogxz 3383 31 ¼ ¼ NNP cord-015369-72cjogxz 3383 32 11 11 CD cord-015369-72cjogxz 3383 33 . . . cord-015369-72cjogxz 3384 1 Complication complication NN cord-015369-72cjogxz 3384 2 and and CC cord-015369-72cjogxz 3384 3 mortality mortality NN cord-015369-72cjogxz 3384 4 rate rate NN cord-015369-72cjogxz 3384 5 was be VBD cord-015369-72cjogxz 3384 6 4.3 4.3 CD cord-015369-72cjogxz 3384 7 % % NN cord-015369-72cjogxz 3384 8 . . . cord-015369-72cjogxz 3385 1 Mean mean JJ cord-015369-72cjogxz 3385 2 ICU ICU NNP cord-015369-72cjogxz 3385 3 stay stay NN cord-015369-72cjogxz 3385 4 was be VBD cord-015369-72cjogxz 3386 1 2 2 CD cord-015369-72cjogxz 3386 2 days day NNS cord-015369-72cjogxz 3386 3 , , , cord-015369-72cjogxz 3386 4 hospital hospital NN cord-015369-72cjogxz 3386 5 stay stay NN cord-015369-72cjogxz 3386 6 5 5 CD cord-015369-72cjogxz 3386 7 days day NNS cord-015369-72cjogxz 3386 8 . . . cord-015369-72cjogxz 3387 1 With with IN cord-015369-72cjogxz 3387 2 the the DT cord-015369-72cjogxz 3387 3 avoidance avoidance NN cord-015369-72cjogxz 3387 4 of of IN cord-015369-72cjogxz 3387 5 a a DT cord-015369-72cjogxz 3387 6 median median JJ cord-015369-72cjogxz 3387 7 sternotomy sternotomy NN cord-015369-72cjogxz 3387 8 , , , cord-015369-72cjogxz 3387 9 the the DT cord-015369-72cjogxz 3387 10 mobility mobility NN cord-015369-72cjogxz 3387 11 of of IN cord-015369-72cjogxz 3387 12 the the DT cord-015369-72cjogxz 3387 13 patient patient NN cord-015369-72cjogxz 3387 14 postoperatively postoperatively RB cord-015369-72cjogxz 3387 15 is be VBZ cord-015369-72cjogxz 3387 16 increased increase VBN cord-015369-72cjogxz 3387 17 . . . cord-015369-72cjogxz 3388 1 Furthermore furthermore RB cord-015369-72cjogxz 3388 2 the the DT cord-015369-72cjogxz 3388 3 patients patient NNS cord-015369-72cjogxz 3388 4 appreciated appreciate VBD cord-015369-72cjogxz 3388 5 the the DT cord-015369-72cjogxz 3388 6 cosmetic cosmetic JJ cord-015369-72cjogxz 3388 7 aspect aspect NN cord-015369-72cjogxz 3388 8 and and CC cord-015369-72cjogxz 3388 9 the the DT cord-015369-72cjogxz 3388 10 possibility possibility NN cord-015369-72cjogxz 3388 11 to to TO cord-015369-72cjogxz 3388 12 return return VB cord-015369-72cjogxz 3388 13 to to IN cord-015369-72cjogxz 3388 14 daily daily JJ cord-015369-72cjogxz 3388 15 activity activity NN cord-015369-72cjogxz 3388 16 , , , cord-015369-72cjogxz 3388 17 sports sport NNS cord-015369-72cjogxz 3388 18 and and CC cord-015369-72cjogxz 3388 19 job job NN cord-015369-72cjogxz 3388 20 in in IN cord-015369-72cjogxz 3388 21 a a DT cord-015369-72cjogxz 3388 22 shorter short JJR cord-015369-72cjogxz 3388 23 time time NN cord-015369-72cjogxz 3388 24 . . . cord-015369-72cjogxz 3389 1 From from IN cord-015369-72cjogxz 3389 2 a a DT cord-015369-72cjogxz 3389 3 surgical surgical JJ cord-015369-72cjogxz 3389 4 point point NN cord-015369-72cjogxz 3389 5 of of IN cord-015369-72cjogxz 3389 6 view view NN cord-015369-72cjogxz 3389 7 , , , cord-015369-72cjogxz 3389 8 the the DT cord-015369-72cjogxz 3389 9 same same JJ cord-015369-72cjogxz 3389 10 technical technical JJ cord-015369-72cjogxz 3389 11 standard standard NN cord-015369-72cjogxz 3389 12 of of IN cord-015369-72cjogxz 3389 13 surgical surgical JJ cord-015369-72cjogxz 3389 14 performance performance NN cord-015369-72cjogxz 3389 15 can can MD cord-015369-72cjogxz 3389 16 be be VB cord-015369-72cjogxz 3389 17 maintained maintain VBN cord-015369-72cjogxz 3389 18 through through IN cord-015369-72cjogxz 3389 19 this this DT cord-015369-72cjogxz 3389 20 approach approach NN cord-015369-72cjogxz 3389 21 after after IN cord-015369-72cjogxz 3389 22 the the DT cord-015369-72cjogxz 3389 23 surgeon surgeon NN cord-015369-72cjogxz 3389 24 becomes become VBZ cord-015369-72cjogxz 3389 25 accustomed accustomed JJ cord-015369-72cjogxz 3389 26 to to IN cord-015369-72cjogxz 3389 27 the the DT cord-015369-72cjogxz 3389 28 instruments instrument NNS cord-015369-72cjogxz 3389 29 and and CC cord-015369-72cjogxz 3389 30 exposure exposure NN cord-015369-72cjogxz 3389 31 . . . cord-015369-72cjogxz 3390 1 Background background NN cord-015369-72cjogxz 3390 2 . . . cord-015369-72cjogxz 3391 1 Atrial atrial JJ cord-015369-72cjogxz 3391 2 Septal Septal NNP cord-015369-72cjogxz 3391 3 Defects Defects NNP cord-015369-72cjogxz 3391 4 ( ( -LRB- cord-015369-72cjogxz 3391 5 ASD ASD NNP cord-015369-72cjogxz 3391 6 ) ) -RRB- cord-015369-72cjogxz 3391 7 apply apply VBP cord-015369-72cjogxz 3391 8 for for IN cord-015369-72cjogxz 3391 9 5 5 CD cord-015369-72cjogxz 3391 10 - - SYM cord-015369-72cjogxz 3391 11 10 10 CD cord-015369-72cjogxz 3391 12 % % NN cord-015369-72cjogxz 3391 13 of of IN cord-015369-72cjogxz 3391 14 congenital congenital JJ cord-015369-72cjogxz 3391 15 heart heart NN cord-015369-72cjogxz 3391 16 disease disease NN cord-015369-72cjogxz 3391 17 . . . cord-015369-72cjogxz 3392 1 The the DT cord-015369-72cjogxz 3392 2 standard standard JJ cord-015369-72cjogxz 3392 3 surgical surgical JJ cord-015369-72cjogxz 3392 4 approach approach NN cord-015369-72cjogxz 3392 5 used use VBN cord-015369-72cjogxz 3392 6 to to TO cord-015369-72cjogxz 3392 7 be be VB cord-015369-72cjogxz 3392 8 median median JJ cord-015369-72cjogxz 3392 9 sternotomy sternotomy NN cord-015369-72cjogxz 3392 10 . . . cord-015369-72cjogxz 3393 1 We -PRON- PRP cord-015369-72cjogxz 3393 2 reviewed review VBD cord-015369-72cjogxz 3393 3 our -PRON- PRP$ cord-015369-72cjogxz 3393 4 experience experience NN cord-015369-72cjogxz 3393 5 on on IN cord-015369-72cjogxz 3393 6 the the DT cord-015369-72cjogxz 3393 7 development development NN cord-015369-72cjogxz 3393 8 of of IN cord-015369-72cjogxz 3393 9 a a DT cord-015369-72cjogxz 3393 10 minimally minimally RB cord-015369-72cjogxz 3393 11 invasive invasive JJ cord-015369-72cjogxz 3393 12 surgical surgical JJ cord-015369-72cjogxz 3393 13 technique technique NN cord-015369-72cjogxz 3393 14 and and CC cord-015369-72cjogxz 3393 15 its -PRON- PRP$ cord-015369-72cjogxz 3393 16 introduction introduction NN cord-015369-72cjogxz 3393 17 into into IN cord-015369-72cjogxz 3393 18 clinical clinical JJ cord-015369-72cjogxz 3393 19 routine routine NN cord-015369-72cjogxz 3393 20 . . . cord-015369-72cjogxz 3394 1 Methods method NNS cord-015369-72cjogxz 3394 2 . . . cord-015369-72cjogxz 3395 1 We -PRON- PRP cord-015369-72cjogxz 3395 2 reviewed review VBD cord-015369-72cjogxz 3395 3 all all DT cord-015369-72cjogxz 3395 4 patients patient NNS cord-015369-72cjogxz 3395 5 who who WP cord-015369-72cjogxz 3395 6 underwent undergo VBD cord-015369-72cjogxz 3395 7 surgical surgical JJ cord-015369-72cjogxz 3395 8 ASD asd NN cord-015369-72cjogxz 3395 9 - - HYPH cord-015369-72cjogxz 3395 10 closure closure NN cord-015369-72cjogxz 3395 11 at at IN cord-015369-72cjogxz 3395 12 our -PRON- PRP$ cord-015369-72cjogxz 3395 13 institution institution NN cord-015369-72cjogxz 3395 14 from from IN cord-015369-72cjogxz 3395 15 01/2001 01/2001 CD cord-015369-72cjogxz 3395 16 - - HYPH cord-015369-72cjogxz 3395 17 12/2008 12/2008 CD cord-015369-72cjogxz 3395 18 . . . cord-015369-72cjogxz 3396 1 Analysis analysis NN cord-015369-72cjogxz 3396 2 was be VBD cord-015369-72cjogxz 3396 3 performed perform VBN cord-015369-72cjogxz 3396 4 concerning concern VBG cord-015369-72cjogxz 3396 5 ASD asd NN cord-015369-72cjogxz 3396 6 - - HYPH cord-015369-72cjogxz 3396 7 pathology pathology NN cord-015369-72cjogxz 3396 8 , , , cord-015369-72cjogxz 3396 9 patient patient NN cord-015369-72cjogxz 3396 10 characteristics characteristic NNS cord-015369-72cjogxz 3396 11 and and CC cord-015369-72cjogxz 3396 12 operative operative JJ cord-015369-72cjogxz 3396 13 variables variable NNS cord-015369-72cjogxz 3396 14 . . . cord-015369-72cjogxz 3397 1 Results result NNS cord-015369-72cjogxz 3397 2 . . . cord-015369-72cjogxz 3398 1 From from IN cord-015369-72cjogxz 3398 2 01/2001 01/2001 CD cord-015369-72cjogxz 3398 3 through through IN cord-015369-72cjogxz 3398 4 12/2008 12/2008 CD cord-015369-72cjogxz 3398 5 , , , cord-015369-72cjogxz 3398 6 171 171 CD cord-015369-72cjogxz 3398 7 patients patient NNS cord-015369-72cjogxz 3398 8 underwent undergo VBD cord-015369-72cjogxz 3398 9 isolated isolated JJ cord-015369-72cjogxz 3398 10 ASD ASD NNP cord-015369-72cjogxz 3398 11 - - HYPH cord-015369-72cjogxz 3398 12 closure closure NN cord-015369-72cjogxz 3398 13 . . . cord-015369-72cjogxz 3399 1 In in IN cord-015369-72cjogxz 3399 2 that that DT cord-015369-72cjogxz 3399 3 period period NN cord-015369-72cjogxz 3399 4 , , , cord-015369-72cjogxz 3399 5 27 27 CD cord-015369-72cjogxz 3399 6 operations operation NNS cord-015369-72cjogxz 3399 7 were be VBD cord-015369-72cjogxz 3399 8 performed perform VBN cord-015369-72cjogxz 3399 9 in in IN cord-015369-72cjogxz 3399 10 a a DT cord-015369-72cjogxz 3399 11 minimally minimally RB cord-015369-72cjogxz 3399 12 invasive invasive JJ cord-015369-72cjogxz 3399 13 technique technique NN cord-015369-72cjogxz 3399 14 through through IN cord-015369-72cjogxz 3399 15 a a DT cord-015369-72cjogxz 3399 16 right right RB cord-015369-72cjogxz 3399 17 - - HYPH cord-015369-72cjogxz 3399 18 sided sided JJ cord-015369-72cjogxz 3399 19 minithoracotomy minithoracotomy NN cord-015369-72cjogxz 3399 20 and and CC cord-015369-72cjogxz 3399 21 remote remote JJ cord-015369-72cjogxz 3399 22 - - HYPH cord-015369-72cjogxz 3399 23 access access NN cord-015369-72cjogxz 3399 24 perfusion perfusion NN cord-015369-72cjogxz 3399 25 through through IN cord-015369-72cjogxz 3399 26 the the DT cord-015369-72cjogxz 3399 27 right right JJ cord-015369-72cjogxz 3399 28 groin groin NN cord-015369-72cjogxz 3399 29 . . . cord-015369-72cjogxz 3400 1 In in IN cord-015369-72cjogxz 3400 2 2001 2001 CD cord-015369-72cjogxz 3400 3 , , , cord-015369-72cjogxz 3400 4 the the DT cord-015369-72cjogxz 3400 5 development development NN cord-015369-72cjogxz 3400 6 of of IN cord-015369-72cjogxz 3400 7 the the DT cord-015369-72cjogxz 3400 8 technique technique NN cord-015369-72cjogxz 3400 9 started start VBD cord-015369-72cjogxz 3400 10 using use VBG cord-015369-72cjogxz 3400 11 the the DT cord-015369-72cjogxz 3400 12 heartport heartport NN cord-015369-72cjogxz 3400 13 - - HYPH cord-015369-72cjogxz 3400 14 perfusion perfusion NN cord-015369-72cjogxz 3400 15 system system NN cord-015369-72cjogxz 3400 16 ( ( -LRB- cord-015369-72cjogxz 3400 17 5 5 CD cord-015369-72cjogxz 3400 18 pts pts CD cord-015369-72cjogxz 3400 19 ) ) -RRB- cord-015369-72cjogxz 3400 20 . . . cord-015369-72cjogxz 3401 1 Thereafter thereafter RB cord-015369-72cjogxz 3401 2 we -PRON- PRP cord-015369-72cjogxz 3401 3 started start VBD cord-015369-72cjogxz 3401 4 to to TO cord-015369-72cjogxz 3401 5 use use VB cord-015369-72cjogxz 3401 6 Chitwood Chitwood NNP cord-015369-72cjogxz 3401 7 - - HYPH cord-015369-72cjogxz 3401 8 clamp clamp NN cord-015369-72cjogxz 3401 9 . . . cord-015369-72cjogxz 3402 1 16 16 CD cord-015369-72cjogxz 3402 2 defects defect NNS cord-015369-72cjogxz 3402 3 were be VBD cord-015369-72cjogxz 3402 4 closed close VBN cord-015369-72cjogxz 3402 5 by by IN cord-015369-72cjogxz 3402 6 direct direct JJ cord-015369-72cjogxz 3402 7 suture suture NN cord-015369-72cjogxz 3402 8 , , , cord-015369-72cjogxz 3402 9 10 10 CD cord-015369-72cjogxz 3402 10 by by IN cord-015369-72cjogxz 3402 11 patch patch NN cord-015369-72cjogxz 3402 12 closure closure NN cord-015369-72cjogxz 3402 13 . . . cord-015369-72cjogxz 3403 1 During during IN cord-015369-72cjogxz 3403 2 the the DT cord-015369-72cjogxz 3403 3 last last JJ cord-015369-72cjogxz 3403 4 three three CD cord-015369-72cjogxz 3403 5 years year NNS cord-015369-72cjogxz 3403 6 , , , cord-015369-72cjogxz 3403 7 the the DT cord-015369-72cjogxz 3403 8 number number NN cord-015369-72cjogxz 3403 9 of of IN cord-015369-72cjogxz 3403 10 patients patient NNS cord-015369-72cjogxz 3403 11 undergoing undergo VBG cord-015369-72cjogxz 3403 12 minimally minimally RB cord-015369-72cjogxz 3403 13 invasive invasive JJ cord-015369-72cjogxz 3403 14 surgery surgery NN cord-015369-72cjogxz 3403 15 , , , cord-015369-72cjogxz 3403 16 is be VBZ cord-015369-72cjogxz 3403 17 rising rise VBG cord-015369-72cjogxz 3403 18 steadily steadily RB cord-015369-72cjogxz 3403 19 ( ( -LRB- cord-015369-72cjogxz 3403 20 2006 2006 CD cord-015369-72cjogxz 3403 21 : : SYM cord-015369-72cjogxz 3403 22 4 4 CD cord-015369-72cjogxz 3403 23 pts pt NNS cord-015369-72cjogxz 3403 24 , , , cord-015369-72cjogxz 3403 25 2007 2007 CD cord-015369-72cjogxz 3403 26 : : SYM cord-015369-72cjogxz 3403 27 6 6 CD cord-015369-72cjogxz 3403 28 pts pt NNS cord-015369-72cjogxz 3403 29 , , , cord-015369-72cjogxz 3403 30 2008 2008 CD cord-015369-72cjogxz 3403 31 : : SYM cord-015369-72cjogxz 3403 32 6 6 CD cord-015369-72cjogxz 3403 33 pts pts CD cord-015369-72cjogxz 3403 34 ) ) -RRB- cord-015369-72cjogxz 3403 35 . . . cord-015369-72cjogxz 3404 1 In in IN cord-015369-72cjogxz 3404 2 2007 2007 CD cord-015369-72cjogxz 3404 3 , , , cord-015369-72cjogxz 3404 4 the the DT cord-015369-72cjogxz 3404 5 first first JJ cord-015369-72cjogxz 3404 6 Sinus Sinus NNP cord-015369-72cjogxz 3404 7 Venosus Venosus NNP cord-015369-72cjogxz 3404 8 Defect Defect NNP cord-015369-72cjogxz 3404 9 was be VBD cord-015369-72cjogxz 3404 10 successfully successfully RB cord-015369-72cjogxz 3404 11 treated treat VBN cord-015369-72cjogxz 3404 12 in in IN cord-015369-72cjogxz 3404 13 that that DT cord-015369-72cjogxz 3404 14 fashion fashion NN cord-015369-72cjogxz 3404 15 . . . cord-015369-72cjogxz 3405 1 Furthermore furthermore RB cord-015369-72cjogxz 3405 2 , , , cord-015369-72cjogxz 3405 3 the the DT cord-015369-72cjogxz 3405 4 technique technique NN cord-015369-72cjogxz 3405 5 is be VBZ cord-015369-72cjogxz 3405 6 also also RB cord-015369-72cjogxz 3405 7 applicable applicable JJ cord-015369-72cjogxz 3405 8 for for IN cord-015369-72cjogxz 3405 9 treatment treatment NN cord-015369-72cjogxz 3405 10 of of IN cord-015369-72cjogxz 3405 11 dislocated dislocated JJ cord-015369-72cjogxz 3405 12 interventional interventional JJ cord-015369-72cjogxz 3405 13 occluding occluding NN cord-015369-72cjogxz 3405 14 devices device NNS cord-015369-72cjogxz 3405 15 ( ( -LRB- cord-015369-72cjogxz 3405 16 2 2 CD cord-015369-72cjogxz 3405 17 pts pts CD cord-015369-72cjogxz 3405 18 ) ) -RRB- cord-015369-72cjogxz 3405 19 . . . cord-015369-72cjogxz 3406 1 The the DT cord-015369-72cjogxz 3406 2 mean mean JJ cord-015369-72cjogxz 3406 3 age age NN cord-015369-72cjogxz 3406 4 of of IN cord-015369-72cjogxz 3406 5 the the DT cord-015369-72cjogxz 3406 6 patients patient NNS cord-015369-72cjogxz 3406 7 was be VBD cord-015369-72cjogxz 3406 8 40.7 40.7 CD cord-015369-72cjogxz 3406 9 years year NNS cord-015369-72cjogxz 3406 10 ( ( -LRB- cord-015369-72cjogxz 3406 11 11 11 CD cord-015369-72cjogxz 3406 12 - - SYM cord-015369-72cjogxz 3406 13 71 71 CD cord-015369-72cjogxz 3406 14 yrs yr NNS cord-015369-72cjogxz 3406 15 ) ) -RRB- cord-015369-72cjogxz 3406 16 , , , cord-015369-72cjogxz 3406 17 mean mean JJ cord-015369-72cjogxz 3406 18 weight weight NN cord-015369-72cjogxz 3406 19 was be VBD cord-015369-72cjogxz 3406 20 70.2 70.2 CD cord-015369-72cjogxz 3406 21 kg kg NNP cord-015369-72cjogxz 3406 22 ( ( -LRB- cord-015369-72cjogxz 3406 23 55 55 CD cord-015369-72cjogxz 3406 24 - - SYM cord-015369-72cjogxz 3406 25 98 98 CD cord-015369-72cjogxz 3406 26 kg kg NNS cord-015369-72cjogxz 3406 27 ) ) -RRB- cord-015369-72cjogxz 3406 28 . . . cord-015369-72cjogxz 3407 1 Mean mean JJ cord-015369-72cjogxz 3407 2 aortic aortic JJ cord-015369-72cjogxz 3407 3 crossclamp crossclamp NN cord-015369-72cjogxz 3407 4 time time NN cord-015369-72cjogxz 3407 5 was be VBD cord-015369-72cjogxz 3407 6 53.7 53.7 CD cord-015369-72cjogxz 3407 7 min min NN cord-015369-72cjogxz 3407 8 . . . cord-015369-72cjogxz 3408 1 There there EX cord-015369-72cjogxz 3408 2 was be VBD cord-015369-72cjogxz 3408 3 no no DT cord-015369-72cjogxz 3408 4 operative operative JJ cord-015369-72cjogxz 3408 5 death death NN cord-015369-72cjogxz 3408 6 and and CC cord-015369-72cjogxz 3408 7 no no DT cord-015369-72cjogxz 3408 8 patient patient NN cord-015369-72cjogxz 3408 9 had have VBD cord-015369-72cjogxz 3408 10 to to TO cord-015369-72cjogxz 3408 11 be be VB cord-015369-72cjogxz 3408 12 converted convert VBN cord-015369-72cjogxz 3408 13 to to IN cord-015369-72cjogxz 3408 14 median median JJ cord-015369-72cjogxz 3408 15 sternotomy sternotomy NN cord-015369-72cjogxz 3408 16 . . . cord-015369-72cjogxz 3409 1 Conclusions conclusion NNS cord-015369-72cjogxz 3409 2 . . . cord-015369-72cjogxz 3410 1 Minimally minimally RB cord-015369-72cjogxz 3410 2 invasive invasive JJ cord-015369-72cjogxz 3410 3 ASD asd NN cord-015369-72cjogxz 3410 4 - - HYPH cord-015369-72cjogxz 3410 5 closure closure NN cord-015369-72cjogxz 3410 6 via via IN cord-015369-72cjogxz 3410 7 a a DT cord-015369-72cjogxz 3410 8 right right RB cord-015369-72cjogxz 3410 9 - - HYPH cord-015369-72cjogxz 3410 10 sided sided JJ cord-015369-72cjogxz 3410 11 minithoracotomy minithoracotomy NN cord-015369-72cjogxz 3410 12 has have VBZ cord-015369-72cjogxz 3410 13 successfully successfully RB cord-015369-72cjogxz 3410 14 been be VBN cord-015369-72cjogxz 3410 15 introduced introduce VBN cord-015369-72cjogxz 3410 16 into into IN cord-015369-72cjogxz 3410 17 clinical clinical JJ cord-015369-72cjogxz 3410 18 routine routine NN cord-015369-72cjogxz 3410 19 at at IN cord-015369-72cjogxz 3410 20 our -PRON- PRP$ cord-015369-72cjogxz 3410 21 institution institution NN cord-015369-72cjogxz 3410 22 . . . cord-015369-72cjogxz 3411 1 With with IN cord-015369-72cjogxz 3411 2 growing grow VBG cord-015369-72cjogxz 3411 3 experience experience NN cord-015369-72cjogxz 3411 4 even even RB cord-015369-72cjogxz 3411 5 Sinus Sinus NNP cord-015369-72cjogxz 3411 6 Venosus Venosus NNP cord-015369-72cjogxz 3411 7 Defects Defects NNP cord-015369-72cjogxz 3411 8 and and CC cord-015369-72cjogxz 3411 9 dislocated dislocate VBN cord-015369-72cjogxz 3411 10 occluding occlude VBG cord-015369-72cjogxz 3411 11 devices device NNS cord-015369-72cjogxz 3411 12 can can MD cord-015369-72cjogxz 3411 13 be be VB cord-015369-72cjogxz 3411 14 operated operate VBN cord-015369-72cjogxz 3411 15 on on IN cord-015369-72cjogxz 3411 16 safely safely RB cord-015369-72cjogxz 3411 17 and and CC cord-015369-72cjogxz 3411 18 with with IN cord-015369-72cjogxz 3411 19 good good JJ cord-015369-72cjogxz 3411 20 results result NNS cord-015369-72cjogxz 3411 21 . . . cord-015369-72cjogxz 3412 1 Background background NN cord-015369-72cjogxz 3412 2 . . . cord-015369-72cjogxz 3413 1 The the DT cord-015369-72cjogxz 3413 2 Levitronix Levitronix NNP cord-015369-72cjogxz 3413 3 Centrimag Centrimag NNP cord-015369-72cjogxz 3413 4 device device NN cord-015369-72cjogxz 3413 5 is be VBZ cord-015369-72cjogxz 3413 6 a a DT cord-015369-72cjogxz 3413 7 centrifugal centrifugal JJ cord-015369-72cjogxz 3413 8 pump pump NN cord-015369-72cjogxz 3413 9 designed design VBN cord-015369-72cjogxz 3413 10 for for IN cord-015369-72cjogxz 3413 11 short short JJ cord-015369-72cjogxz 3413 12 term term NN cord-015369-72cjogxz 3413 13 support support NN cord-015369-72cjogxz 3413 14 in in IN cord-015369-72cjogxz 3413 15 cardiogenic cardiogenic JJ cord-015369-72cjogxz 3413 16 shock shock NN cord-015369-72cjogxz 3413 17 . . . cord-015369-72cjogxz 3414 1 It -PRON- PRP cord-015369-72cjogxz 3414 2 is be VBZ cord-015369-72cjogxz 3414 3 implantable implantable JJ cord-015369-72cjogxz 3414 4 both both DT cord-015369-72cjogxz 3414 5 in in IN cord-015369-72cjogxz 3414 6 adults adult NNS cord-015369-72cjogxz 3414 7 and and CC cord-015369-72cjogxz 3414 8 also also RB cord-015369-72cjogxz 3414 9 in in IN cord-015369-72cjogxz 3414 10 pediatric pediatric JJ cord-015369-72cjogxz 3414 11 pts pt NNS cord-015369-72cjogxz 3414 12 . . . cord-015369-72cjogxz 3415 1 We -PRON- PRP cord-015369-72cjogxz 3415 2 report report VBP cord-015369-72cjogxz 3415 3 our -PRON- PRP$ cord-015369-72cjogxz 3415 4 experiences experience NNS cord-015369-72cjogxz 3415 5 using use VBG cord-015369-72cjogxz 3415 6 the the DT cord-015369-72cjogxz 3415 7 Centrimag Centrimag NNP cord-015369-72cjogxz 3415 8 device device NN cord-015369-72cjogxz 3415 9 in in IN cord-015369-72cjogxz 3415 10 all all DT cord-015369-72cjogxz 3415 11 forms form NNS cord-015369-72cjogxz 3415 12 of of IN cord-015369-72cjogxz 3415 13 cardiogenic cardiogenic JJ cord-015369-72cjogxz 3415 14 shock shock NN cord-015369-72cjogxz 3415 15 ( ( -LRB- cord-015369-72cjogxz 3415 16 postoperative postoperative JJ cord-015369-72cjogxz 3415 17 LCOS LCOS NNP cord-015369-72cjogxz 3415 18 , , , cord-015369-72cjogxz 3415 19 myocarditis myocarditis NN cord-015369-72cjogxz 3415 20 , , , cord-015369-72cjogxz 3415 21 pre pre JJ cord-015369-72cjogxz 3415 22 - - NNP cord-015369-72cjogxz 3415 23 Htx htx JJ cord-015369-72cjogxz 3415 24 , , , cord-015369-72cjogxz 3415 25 right right JJ cord-015369-72cjogxz 3415 26 heart heart NN cord-015369-72cjogxz 3415 27 failure failure NN cord-015369-72cjogxz 3415 28 post post NNP cord-015369-72cjogxz 3416 1 Htx Htx NNP cord-015369-72cjogxz 3416 2 , , , cord-015369-72cjogxz 3416 3 acute acute JJ cord-015369-72cjogxz 3416 4 myocardial myocardial JJ cord-015369-72cjogxz 3416 5 infarction infarction NN cord-015369-72cjogxz 3416 6 ) ) -RRB- cord-015369-72cjogxz 3416 7 in in IN cord-015369-72cjogxz 3416 8 the the DT cord-015369-72cjogxz 3416 9 adult adult NN cord-015369-72cjogxz 3416 10 population population NN cord-015369-72cjogxz 3416 11 . . . cord-015369-72cjogxz 3417 1 Methods method NNS cord-015369-72cjogxz 3417 2 . . . cord-015369-72cjogxz 3418 1 We -PRON- PRP cord-015369-72cjogxz 3418 2 have have VBP cord-015369-72cjogxz 3418 3 implanted implant VBN cord-015369-72cjogxz 3418 4 in in IN cord-015369-72cjogxz 3418 5 a a DT cord-015369-72cjogxz 3418 6 four four CD cord-015369-72cjogxz 3418 7 - - HYPH cord-015369-72cjogxz 3418 8 year year NN cord-015369-72cjogxz 3418 9 period period NN cord-015369-72cjogxz 3418 10 the the DT cord-015369-72cjogxz 3418 11 Centrimag Centrimag NNP cord-015369-72cjogxz 3418 12 device device NN cord-015369-72cjogxz 3418 13 in in IN cord-015369-72cjogxz 3418 14 227 227 CD cord-015369-72cjogxz 3418 15 adult adult NN cord-015369-72cjogxz 3418 16 pts pt NNS cord-015369-72cjogxz 3418 17 ( ( -LRB- cord-015369-72cjogxz 3418 18 mean mean VB cord-015369-72cjogxz 3418 19 age age NN cord-015369-72cjogxz 3418 20 59.5 59.5 CD cord-015369-72cjogxz 3418 21 years year NNS cord-015369-72cjogxz 3418 22 ) ) -RRB- cord-015369-72cjogxz 3418 23 . . . cord-015369-72cjogxz 3419 1 The the DT cord-015369-72cjogxz 3419 2 cumulative cumulative JJ cord-015369-72cjogxz 3419 3 experience experience NN cord-015369-72cjogxz 3419 4 was be VBD cord-015369-72cjogxz 3419 5 6 6 CD cord-015369-72cjogxz 3419 6 years year NNS cord-015369-72cjogxz 3419 7 . . . cord-015369-72cjogxz 3420 1 The the DT cord-015369-72cjogxz 3420 2 device device NN cord-015369-72cjogxz 3420 3 was be VBD cord-015369-72cjogxz 3420 4 implanted implant VBN cord-015369-72cjogxz 3420 5 in in IN cord-015369-72cjogxz 3420 6 158 158 CD cord-015369-72cjogxz 3420 7 cases case NNS cord-015369-72cjogxz 3420 8 as as IN cord-015369-72cjogxz 3420 9 femoro femoro JJ cord-015369-72cjogxz 3420 10 - - HYPH cord-015369-72cjogxz 3420 11 femoral femoral JJ cord-015369-72cjogxz 3420 12 bypass bypass NN cord-015369-72cjogxz 3420 13 , , , cord-015369-72cjogxz 3420 14 in in IN cord-015369-72cjogxz 3420 15 the the DT cord-015369-72cjogxz 3420 16 66 66 CD cord-015369-72cjogxz 3420 17 cases case NNS cord-015369-72cjogxz 3420 18 intraoperatively intraoperatively RB cord-015369-72cjogxz 3420 19 by by IN cord-015369-72cjogxz 3420 20 cannulating cannulate VBG cord-015369-72cjogxz 3420 21 the the DT cord-015369-72cjogxz 3420 22 left left JJ cord-015369-72cjogxz 3420 23 atrium atrium NN cord-015369-72cjogxz 3420 24 and and CC cord-015369-72cjogxz 3420 25 the the DT cord-015369-72cjogxz 3420 26 ascending ascend VBG cord-015369-72cjogxz 3420 27 aorta aorta NN cord-015369-72cjogxz 3420 28 and and CC cord-015369-72cjogxz 3420 29 in in IN cord-015369-72cjogxz 3420 30 the the DT cord-015369-72cjogxz 3420 31 remaining remain VBG cord-015369-72cjogxz 3420 32 three three CD cord-015369-72cjogxz 3420 33 cases case NNS cord-015369-72cjogxz 3420 34 by by IN cord-015369-72cjogxz 3420 35 cannulating cannulate VBG cord-015369-72cjogxz 3420 36 the the DT cord-015369-72cjogxz 3420 37 right right JJ cord-015369-72cjogxz 3420 38 atrium atrium NN cord-015369-72cjogxz 3420 39 and and CC cord-015369-72cjogxz 3420 40 the the DT cord-015369-72cjogxz 3420 41 pulmonary pulmonary JJ cord-015369-72cjogxz 3420 42 artery artery NN cord-015369-72cjogxz 3420 43 ( ( -LRB- cord-015369-72cjogxz 3420 44 right right JJ cord-015369-72cjogxz 3420 45 heart heart NN cord-015369-72cjogxz 3420 46 failure failure NN cord-015369-72cjogxz 3420 47 after after IN cord-015369-72cjogxz 3420 48 Htx Htx NNP cord-015369-72cjogxz 3420 49 ) ) -RRB- cord-015369-72cjogxz 3420 50 . . . cord-015369-72cjogxz 3421 1 The the DT cord-015369-72cjogxz 3421 2 mean mean JJ cord-015369-72cjogxz 3421 3 support support NN cord-015369-72cjogxz 3421 4 time time NN cord-015369-72cjogxz 3421 5 was be VBD cord-015369-72cjogxz 3421 6 9.8 9.8 CD cord-015369-72cjogxz 3421 7 days day NNS cord-015369-72cjogxz 3421 8 ( ( -LRB- cord-015369-72cjogxz 3421 9 1 1 CD cord-015369-72cjogxz 3421 10 - - SYM cord-015369-72cjogxz 3421 11 183 183 CD cord-015369-72cjogxz 3421 12 days day NNS cord-015369-72cjogxz 3421 13 ) ) -RRB- cord-015369-72cjogxz 3421 14 . . . cord-015369-72cjogxz 3422 1 Results result NNS cord-015369-72cjogxz 3422 2 . . . cord-015369-72cjogxz 3423 1 Fifty fifty CD cord-015369-72cjogxz 3423 2 - - HYPH cord-015369-72cjogxz 3423 3 eight eight CD cord-015369-72cjogxz 3423 4 patients patient NNS cord-015369-72cjogxz 3423 5 ( ( -LRB- cord-015369-72cjogxz 3423 6 26 26 CD cord-015369-72cjogxz 3423 7 % % NN cord-015369-72cjogxz 3423 8 ) ) -RRB- cord-015369-72cjogxz 3423 9 could could MD cord-015369-72cjogxz 3423 10 be be VB cord-015369-72cjogxz 3423 11 successfully successfully RB cord-015369-72cjogxz 3423 12 weaned wean VBN cord-015369-72cjogxz 3423 13 from from IN cord-015369-72cjogxz 3423 14 device device NN cord-015369-72cjogxz 3423 15 . . . cord-015369-72cjogxz 3424 1 In in IN cord-015369-72cjogxz 3424 2 43 43 CD cord-015369-72cjogxz 3424 3 cases case NNS cord-015369-72cjogxz 3424 4 ( ( -LRB- cord-015369-72cjogxz 3424 5 19 19 CD cord-015369-72cjogxz 3424 6 % % NN cord-015369-72cjogxz 3424 7 ) ) -RRB- cord-015369-72cjogxz 3424 8 the the DT cord-015369-72cjogxz 3424 9 Centrimag Centrimag NNP cord-015369-72cjogxz 3424 10 was be VBD cord-015369-72cjogxz 3424 11 used use VBN cord-015369-72cjogxz 3424 12 as as IN cord-015369-72cjogxz 3424 13 a a DT cord-015369-72cjogxz 3424 14 bridge bridge NN cord-015369-72cjogxz 3424 15 to to IN cord-015369-72cjogxz 3424 16 a a DT cord-015369-72cjogxz 3424 17 more more RBR cord-015369-72cjogxz 3424 18 sophisticated sophisticated JJ cord-015369-72cjogxz 3424 19 device device NN cord-015369-72cjogxz 3424 20 ( ( -LRB- cord-015369-72cjogxz 3424 21 CardioWest CardioWest NNP cord-015369-72cjogxz 3424 22 16 16 CD cord-015369-72cjogxz 3424 23 , , , cord-015369-72cjogxz 3424 24 Dura Dura NNP cord-015369-72cjogxz 3424 25 - - HYPH cord-015369-72cjogxz 3424 26 Heart Heart NNP cord-015369-72cjogxz 3424 27 3 3 CD cord-015369-72cjogxz 3424 28 , , , cord-015369-72cjogxz 3424 29 Ventrassist Ventrassist NNP cord-015369-72cjogxz 3424 30 2 2 CD cord-015369-72cjogxz 3424 31 , , , cord-015369-72cjogxz 3424 32 Thoratec Thoratec NNP cord-015369-72cjogxz 3424 33 16 16 CD cord-015369-72cjogxz 3424 34 , , , cord-015369-72cjogxz 3424 35 HeartMate HeartMate NNP cord-015369-72cjogxz 3424 36 II II NNP cord-015369-72cjogxz 3424 37 3 3 CD cord-015369-72cjogxz 3424 38 , , , cord-015369-72cjogxz 3424 39 Incor Incor NNP cord-015369-72cjogxz 3424 40 1 1 CD cord-015369-72cjogxz 3424 41 and and CC cord-015369-72cjogxz 3424 42 Novacor Novacor NNP cord-015369-72cjogxz 3424 43 2 2 CD cord-015369-72cjogxz 3424 44 ) ) -RRB- cord-015369-72cjogxz 3424 45 . . . cord-015369-72cjogxz 3425 1 At at RB cord-015369-72cjogxz 3425 2 least least JJS cord-015369-72cjogxz 3425 3 117 117 CD cord-015369-72cjogxz 3425 4 pts pt NNS cord-015369-72cjogxz 3425 5 . . . cord-015369-72cjogxz 3426 1 ( ( -LRB- cord-015369-72cjogxz 3426 2 51.5 51.5 CD cord-015369-72cjogxz 3426 3 % % NN cord-015369-72cjogxz 3426 4 ) ) -RRB- cord-015369-72cjogxz 3426 5 died die VBD cord-015369-72cjogxz 3426 6 on on IN cord-015369-72cjogxz 3426 7 device device NN cord-015369-72cjogxz 3426 8 , , , cord-015369-72cjogxz 3426 9 mainly mainly RB cord-015369-72cjogxz 3426 10 caused cause VBN cord-015369-72cjogxz 3426 11 by by IN cord-015369-72cjogxz 3426 12 multiorgan multiorgan NNP cord-015369-72cjogxz 3426 13 failure failure NN cord-015369-72cjogxz 3426 14 . . . cord-015369-72cjogxz 3427 1 Three three CD cord-015369-72cjogxz 3427 2 pts pt NNS cord-015369-72cjogxz 3427 3 underwent undergo VBD cord-015369-72cjogxz 3427 4 Htx Htx NNP cord-015369-72cjogxz 3427 5 , , , cord-015369-72cjogxz 3427 6 5 5 CD cord-015369-72cjogxz 3427 7 pts pt NNS cord-015369-72cjogxz 3427 8 are be VBP cord-015369-72cjogxz 3427 9 on on IN cord-015369-72cjogxz 3427 10 support support NN cord-015369-72cjogxz 3427 11 at at IN cord-015369-72cjogxz 3427 12 this this DT cord-015369-72cjogxz 3427 13 moment moment NN cord-015369-72cjogxz 3427 14 . . . cord-015369-72cjogxz 3428 1 Conclusions conclusion NNS cord-015369-72cjogxz 3428 2 . . . cord-015369-72cjogxz 3429 1 The the DT cord-015369-72cjogxz 3429 2 Levitronix Levitronix NNP cord-015369-72cjogxz 3429 3 Centrimag Centrimag NNP cord-015369-72cjogxz 3429 4 seems seem VBZ cord-015369-72cjogxz 3429 5 to to TO cord-015369-72cjogxz 3429 6 be be VB cord-015369-72cjogxz 3429 7 safe safe JJ cord-015369-72cjogxz 3429 8 and and CC cord-015369-72cjogxz 3429 9 effective effective JJ cord-015369-72cjogxz 3429 10 in in IN cord-015369-72cjogxz 3429 11 the the DT cord-015369-72cjogxz 3429 12 treatment treatment NN cord-015369-72cjogxz 3429 13 of of IN cord-015369-72cjogxz 3429 14 nearly nearly RB cord-015369-72cjogxz 3429 15 all all DT cord-015369-72cjogxz 3429 16 kinds kind NNS cord-015369-72cjogxz 3429 17 of of IN cord-015369-72cjogxz 3429 18 cardiogenic cardiogenic JJ cord-015369-72cjogxz 3429 19 shock shock NN cord-015369-72cjogxz 3429 20 achieving achieve VBG cord-015369-72cjogxz 3429 21 rapid rapid JJ cord-015369-72cjogxz 3429 22 and and CC cord-015369-72cjogxz 3429 23 sufficient sufficient JJ cord-015369-72cjogxz 3429 24 circulatory circulatory JJ cord-015369-72cjogxz 3429 25 support support NN cord-015369-72cjogxz 3429 26 and and CC cord-015369-72cjogxz 3429 27 ventricular ventricular JJ cord-015369-72cjogxz 3429 28 unloading unloading NN cord-015369-72cjogxz 3429 29 . . . cord-015369-72cjogxz 3430 1 Bridge bridge NN cord-015369-72cjogxz 3430 2 - - HYPH cord-015369-72cjogxz 3430 3 to to IN cord-015369-72cjogxz 3430 4 - - HYPH cord-015369-72cjogxz 3430 5 recovery recovery NN cord-015369-72cjogxz 3430 6 , , , cord-015369-72cjogxz 3430 7 bridge bridge NN cord-015369-72cjogxz 3430 8 - - HYPH cord-015369-72cjogxz 3430 9 to to IN cord-015369-72cjogxz 3430 10 - - HYPH cord-015369-72cjogxz 3430 11 bridge bridge NN cord-015369-72cjogxz 3430 12 or or CC cord-015369-72cjogxz 3430 13 bridge bridge NN cord-015369-72cjogxz 3430 14 - - HYPH cord-015369-72cjogxz 3430 15 totransplant totransplant NN cord-015369-72cjogxz 3430 16 are be VBP cord-015369-72cjogxz 3430 17 possible possible JJ cord-015369-72cjogxz 3430 18 . . . cord-015369-72cjogxz 3431 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 3431 2 . . . cord-015369-72cjogxz 3432 1 Das Das NNP cord-015369-72cjogxz 3432 2 Ziel Ziel NNP cord-015369-72cjogxz 3433 1 dieser dieser NNP cord-015369-72cjogxz 3433 2 prospektiven prospektiven NNP cord-015369-72cjogxz 3433 3 Studie Studie NNP cord-015369-72cjogxz 3433 4 war war NN cord-015369-72cjogxz 3433 5 es es NNP cord-015369-72cjogxz 3433 6 , , , cord-015369-72cjogxz 3433 7 perioperative perioperative JJ cord-015369-72cjogxz 3433 8 klinische klinische NNP cord-015369-72cjogxz 3433 9 Parameter Parameter NNP cord-015369-72cjogxz 3433 10 zwischen zwischen NNP cord-015369-72cjogxz 3433 11 der der NN cord-015369-72cjogxz 3433 12 minimal minimal JJ cord-015369-72cjogxz 3433 13 extrakorporalen extrakorporalen NN cord-015369-72cjogxz 3433 14 Zirkulation Zirkulation NNP cord-015369-72cjogxz 3433 15 ( ( -LRB- cord-015369-72cjogxz 3433 16 MECC MECC NNP cord-015369-72cjogxz 3433 17 ) ) -RRB- cord-015369-72cjogxz 3433 18 und und RB cord-015369-72cjogxz 3434 1 der der NNP cord-015369-72cjogxz 3434 2 konventionellen konventionellen NNP cord-015369-72cjogxz 3434 3 extrakorporalen extrakorporalen NNP cord-015369-72cjogxz 3434 4 Zirkulation Zirkulation NNP cord-015369-72cjogxz 3434 5 zu zu XX cord-015369-72cjogxz 3435 1 vergleichen vergleichen NNP cord-015369-72cjogxz 3435 2 . . . cord-015369-72cjogxz 3436 1 Methodik Methodik NNP cord-015369-72cjogxz 3436 2 . . . cord-015369-72cjogxz 3437 1 Unter Unter NNP cord-015369-72cjogxz 3437 2 Verwendung Verwendung NNP cord-015369-72cjogxz 3437 3 des des FW cord-015369-72cjogxz 3437 4 MECC MECC NNP cord-015369-72cjogxz 3437 5 - - HYPH cord-015369-72cjogxz 3437 6 Systems Systems NNP cord-015369-72cjogxz 3437 7 wurde wurde NNP cord-015369-72cjogxz 3437 8 eine eine NNP cord-015369-72cjogxz 3437 9 koronare koronare NNP cord-015369-72cjogxz 3438 1 Revaskularisation Revaskularisation NNP cord-015369-72cjogxz 3438 2 bei bei NNP cord-015369-72cjogxz 3439 1 144 144 CD cord-015369-72cjogxz 3439 2 randomisierten randomisierten NNS cord-015369-72cjogxz 3439 3 Patienten Patienten NNP cord-015369-72cjogxz 3439 4 ( ( -LRB- cord-015369-72cjogxz 3440 1 mittleres mittleres NNP cord-015369-72cjogxz 3440 2 Alter alter VBP cord-015369-72cjogxz 3440 3 69,5 69,5 CD cord-015369-72cjogxz 3440 4 Jahre Jahre NNP cord-015369-72cjogxz 3440 5 ( ( -LRB- cord-015369-72cjogxz 3440 6 43 43 CD cord-015369-72cjogxz 3440 7 - - SYM cord-015369-72cjogxz 3440 8 86 86 CD cord-015369-72cjogxz 3440 9 Jahre Jahre NNP cord-015369-72cjogxz 3440 10 ) ) -RRB- cord-015369-72cjogxz 3440 11 , , . cord-015369-72cjogxz 3441 1 ( ( -LRB- cord-015369-72cjogxz 3441 2 Gruppe Gruppe NNP cord-015369-72cjogxz 3441 3 I I NNP cord-015369-72cjogxz 3441 4 ) ) -RRB- cord-015369-72cjogxz 3441 5 durchgeführt durchgeführt NNP cord-015369-72cjogxz 3441 6 . . . cord-015369-72cjogxz 3442 1 In in IN cord-015369-72cjogxz 3442 2 der der NNP cord-015369-72cjogxz 3442 3 Vergleichs Vergleichs NNP cord-015369-72cjogxz 3442 4 - - HYPH cord-015369-72cjogxz 3442 5 Gruppe Gruppe NNP cord-015369-72cjogxz 3442 6 II II NNP cord-015369-72cjogxz 3442 7 ( ( -LRB- cord-015369-72cjogxz 3442 8 n n NNP cord-015369-72cjogxz 3442 9 ¼ ¼ NNP cord-015369-72cjogxz 3442 10 144 144 CD cord-015369-72cjogxz 3442 11 , , , cord-015369-72cjogxz 3442 12 mittleres mittlere NNS cord-015369-72cjogxz 3442 13 Alter alter VB cord-015369-72cjogxz 3442 14 69,10 69,10 CD cord-015369-72cjogxz 3442 15 Jahre Jahre NNP cord-015369-72cjogxz 3442 16 ( ( -LRB- cord-015369-72cjogxz 3442 17 45 45 CD cord-015369-72cjogxz 3442 18 - - SYM cord-015369-72cjogxz 3442 19 86 86 CD cord-015369-72cjogxz 3442 20 Jahre Jahre NNP cord-015369-72cjogxz 3442 21 ) ) -RRB- cord-015369-72cjogxz 3442 22 wurden wurden NNS cord-015369-72cjogxz 3442 23 die die VBP cord-015369-72cjogxz 3443 1 Patienten Patienten NNP cord-015369-72cjogxz 3443 2 mit mit NNP cord-015369-72cjogxz 3443 3 einer einer NNP cord-015369-72cjogxz 3443 4 konventionellen konventionellen NNP cord-015369-72cjogxz 3443 5 extrakorporalen extrakorporalen NNP cord-015369-72cjogxz 3443 6 Zirkulation Zirkulation NNP cord-015369-72cjogxz 3443 7 perfundiert perfundiert NN cord-015369-72cjogxz 3443 8 . . . cord-015369-72cjogxz 3444 1 Die die VB cord-015369-72cjogxz 3444 2 Einstammerkrankungen Einstammerkrankungen NNP cord-015369-72cjogxz 3444 3 , , , cord-015369-72cjogxz 3444 4 sowie sowie UH cord-015369-72cjogxz 3444 5 die die VBP cord-015369-72cjogxz 3444 6 Notfalleingriffe Notfalleingriffe NNP cord-015369-72cjogxz 3444 7 wurden wurden VBN cord-015369-72cjogxz 3444 8 exkludiert exkludiert JJ cord-015369-72cjogxz 3444 9 . . . cord-015369-72cjogxz 3445 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 3445 2 . . . cord-015369-72cjogxz 3446 1 In in IN cord-015369-72cjogxz 3446 2 den den JJ cord-015369-72cjogxz 3446 3 beiden beiden JJ cord-015369-72cjogxz 3446 4 Gruppen Gruppen NNP cord-015369-72cjogxz 3446 5 zeigte zeigte NNP cord-015369-72cjogxz 3446 6 sich sich NNP cord-015369-72cjogxz 3446 7 kein kein NNP cord-015369-72cjogxz 3446 8 signifikanter signifikanter NNP cord-015369-72cjogxz 3446 9 Unterschied Unterschied NNP cord-015369-72cjogxz 3446 10 der der NNP cord-015369-72cjogxz 3446 11 mittleren mittleren NNP cord-015369-72cjogxz 3447 1 Aortenklemmzeit Aortenklemmzeit NNP cord-015369-72cjogxz 3447 2 ( ( -LRB- cord-015369-72cjogxz 3447 3 65 65 CD cord-015369-72cjogxz 3447 4 AE AE NNP cord-015369-72cjogxz 3447 5 19,2 19,2 CD cord-015369-72cjogxz 3447 6 min min NN cord-015369-72cjogxz 3447 7 vs vs IN cord-015369-72cjogxz 3447 8 70 70 CD cord-015369-72cjogxz 3447 9 AE AE NNP cord-015369-72cjogxz 3447 10 11,5 11,5 CD cord-015369-72cjogxz 3447 11 min min NN cord-015369-72cjogxz 3447 12 ) ) -RRB- cord-015369-72cjogxz 3448 1 , , , cord-015369-72cjogxz 3448 2 der der NNP cord-015369-72cjogxz 3448 3 mittleren mittleren NNP cord-015369-72cjogxz 3448 4 extrakorporalen extrakorporalen NNP cord-015369-72cjogxz 3449 1 Perfusionszeit Perfusionszeit NNP cord-015369-72cjogxz 3450 1 ( ( -LRB- cord-015369-72cjogxz 3450 2 111 111 CD cord-015369-72cjogxz 3450 3 AE AE NNP cord-015369-72cjogxz 3450 4 28,1 28,1 CD cord-015369-72cjogxz 3450 5 min min NN cord-015369-72cjogxz 3450 6 vs vs IN cord-015369-72cjogxz 3450 7 115 115 CD cord-015369-72cjogxz 3450 8 AE AE NNP cord-015369-72cjogxz 3450 9 27,4 27,4 CD cord-015369-72cjogxz 3450 10 min min NNP cord-015369-72cjogxz 3450 11 ) ) -RRB- cord-015369-72cjogxz 3450 12 , , , cord-015369-72cjogxz 3450 13 der der NNP cord-015369-72cjogxz 3450 14 mittleren mittleren NNP cord-015369-72cjogxz 3451 1 Anzahl Anzahl NNP cord-015369-72cjogxz 3451 2 der der NNP cord-015369-72cjogxz 3451 3 distalen distalen NNP cord-015369-72cjogxz 3451 4 Anastomosen Anastomosen NNP cord-015369-72cjogxz 3451 5 sowie sowie NNP cord-015369-72cjogxz 3451 6 in in IN cord-015369-72cjogxz 3451 7 der der NNP cord-015369-72cjogxz 3451 8 Anzahl Anzahl NNP cord-015369-72cjogxz 3451 9 der der NNP cord-015369-72cjogxz 3451 10 verwendeten verwendeten VBN cord-015369-72cjogxz 3451 11 Erythrozythenkonzentrate Erythrozythenkonzentrate NNP cord-015369-72cjogxz 3451 12 . . . cord-015369-72cjogxz 3452 1 Es Es NNP cord-015369-72cjogxz 3452 2 kam kam NNP cord-015369-72cjogxz 3452 3 zu zu NNP cord-015369-72cjogxz 3452 4 keiner keiner NNP cord-015369-72cjogxz 3452 5 30 30 CD cord-015369-72cjogxz 3452 6 Tage Tage NNP cord-015369-72cjogxz 3452 7 Mortalität Mortalität NNP cord-015369-72cjogxz 3452 8 . . . cord-015369-72cjogxz 3453 1 Ebenso Ebenso NNP cord-015369-72cjogxz 3453 2 zeigten zeigten NNP cord-015369-72cjogxz 3453 3 die die VBP cord-015369-72cjogxz 3453 4 nach nach NNP cord-015369-72cjogxz 3453 5 6 6 CD cord-015369-72cjogxz 3454 1 , , , cord-015369-72cjogxz 3454 2 24 24 CD cord-015369-72cjogxz 3454 3 und und IN cord-015369-72cjogxz 3454 4 48 48 CD cord-015369-72cjogxz 3454 5 Stunden Stunden NNP cord-015369-72cjogxz 3454 6 postoperativ postoperativ JJ cord-015369-72cjogxz 3454 7 gemessenen gemessenen NN cord-015369-72cjogxz 3454 8 Laborparameter Laborparameter NNP cord-015369-72cjogxz 3454 9 ( ( -LRB- cord-015369-72cjogxz 3454 10 Troponin Troponin NNP cord-015369-72cjogxz 3454 11 T T NNP cord-015369-72cjogxz 3454 12 , , , cord-015369-72cjogxz 3454 13 Kreatinin Kreatinin NNP cord-015369-72cjogxz 3454 14 , , , cord-015369-72cjogxz 3454 15 CK CK NNP cord-015369-72cjogxz 3454 16 , , , cord-015369-72cjogxz 3454 17 CK CK NNP cord-015369-72cjogxz 3454 18 - - HYPH cord-015369-72cjogxz 3454 19 MB MB NNP cord-015369-72cjogxz 3454 20 , , , cord-015369-72cjogxz 3454 21 Thrombozyten Thrombozyten NNP cord-015369-72cjogxz 3454 22 , , , cord-015369-72cjogxz 3454 23 Leukozyten Leukozyten NNP cord-015369-72cjogxz 3454 24 , , , cord-015369-72cjogxz 3454 25 Hämoglobin Hämoglobin NNP cord-015369-72cjogxz 3454 26 , , , cord-015369-72cjogxz 3454 27 Hämatokrit Hämatokrit NNP cord-015369-72cjogxz 3454 28 ) ) -RRB- cord-015369-72cjogxz 3454 29 keinen keinen NNP cord-015369-72cjogxz 3454 30 statistisch statistisch NNP cord-015369-72cjogxz 3454 31 signifikanten signifikanten NNP cord-015369-72cjogxz 3454 32 Unterschied Unterschied NNP cord-015369-72cjogxz 3454 33 . . . cord-015369-72cjogxz 3455 1 Die die VB cord-015369-72cjogxz 3455 2 gemessene gemessene NN cord-015369-72cjogxz 3456 1 Laktatwerte Laktatwerte NNP cord-015369-72cjogxz 3456 2 zeigten zeigten NNP cord-015369-72cjogxz 3457 1 i -PRON- PRP cord-015369-72cjogxz 3457 2 m be VBP cord-015369-72cjogxz 3457 3 Gegensatz Gegensatz NNP cord-015369-72cjogxz 3457 4 dazu dazu NNP cord-015369-72cjogxz 3457 5 ( ( -LRB- cord-015369-72cjogxz 3457 6 intraoperativ intraoperativ JJ cord-015369-72cjogxz 3457 7 0,84 0,84 CD cord-015369-72cjogxz 3457 8 vs vs IN cord-015369-72cjogxz 3457 9 1,39 1,39 CD cord-015369-72cjogxz 3457 10 , , , cord-015369-72cjogxz 3457 11 6 6 CD cord-015369-72cjogxz 3457 12 Stunden Stunden NNP cord-015369-72cjogxz 3457 13 postoperativ postoperativ NN cord-015369-72cjogxz 3457 14 1,12 1,12 CD cord-015369-72cjogxz 3457 15 vs vs IN cord-015369-72cjogxz 3457 16 1,61 1,61 CD cord-015369-72cjogxz 3457 17 , , , cord-015369-72cjogxz 3457 18 24 24 CD cord-015369-72cjogxz 3457 19 Stunden Stunden NNP cord-015369-72cjogxz 3457 20 postoperativ postoperativ NN cord-015369-72cjogxz 3457 21 1,41 1,41 CD cord-015369-72cjogxz 3457 22 vs vs IN cord-015369-72cjogxz 3457 23 1,61 1,61 CD cord-015369-72cjogxz 3457 24 ) ) -RRB- cord-015369-72cjogxz 3458 1 statistisch statistisch NNP cord-015369-72cjogxz 3458 2 signifikante signifikante NNP cord-015369-72cjogxz 3459 1 Vorteile Vorteile NNP cord-015369-72cjogxz 3459 2 für für FW cord-015369-72cjogxz 3459 3 das das NNP cord-015369-72cjogxz 3459 4 MECC MECC NNP cord-015369-72cjogxz 3459 5 - - HYPH cord-015369-72cjogxz 3459 6 System System NNP cord-015369-72cjogxz 3459 7 . . . cord-015369-72cjogxz 3460 1 Die die VB cord-015369-72cjogxz 3460 2 Aufenthaltsdauer Aufenthaltsdauer NNP cord-015369-72cjogxz 3460 3 auf auf NN cord-015369-72cjogxz 3460 4 der der NNP cord-015369-72cjogxz 3460 5 Intensivstation Intensivstation NNP cord-015369-72cjogxz 3460 6 war war NN cord-015369-72cjogxz 3460 7 in in IN cord-015369-72cjogxz 3460 8 der der NNP cord-015369-72cjogxz 3460 9 Gruppe Gruppe NNP cord-015369-72cjogxz 3460 10 I -PRON- PRP cord-015369-72cjogxz 3460 11 signifikant signifikant VBP cord-015369-72cjogxz 3460 12 kürzer kürzer NNP cord-015369-72cjogxz 3460 13 als als NNP cord-015369-72cjogxz 3460 14 in in IN cord-015369-72cjogxz 3460 15 der der NNP cord-015369-72cjogxz 3460 16 Gruppe Gruppe NNP cord-015369-72cjogxz 3460 17 II II NNP cord-015369-72cjogxz 3461 1 ( ( -LRB- cord-015369-72cjogxz 3461 2 2,21 2,21 CD cord-015369-72cjogxz 3461 3 Tage tage NN cord-015369-72cjogxz 3461 4 vs vs IN cord-015369-72cjogxz 3461 5 2,60 2,60 CD cord-015369-72cjogxz 3461 6 Tage Tage NNP cord-015369-72cjogxz 3461 7 ) ) -RRB- cord-015369-72cjogxz 3461 8 . . . cord-015369-72cjogxz 3462 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 3462 2 . . . cord-015369-72cjogxz 3463 1 Zusätzlich Zusätzlich NNP cord-015369-72cjogxz 3463 2 zu zu NNP cord-015369-72cjogxz 3463 3 der der NNP cord-015369-72cjogxz 3463 4 aus aus NNP cord-015369-72cjogxz 3463 5 der der NNP cord-015369-72cjogxz 3463 6 Literatur Literatur NNP cord-015369-72cjogxz 3464 1 bekannten bekannten NNP cord-015369-72cjogxz 3464 2 Reduktion Reduktion NNP cord-015369-72cjogxz 3464 3 von von NNP cord-015369-72cjogxz 3464 4 Entzündungsmediatoren Entzündungsmediatoren NNP cord-015369-72cjogxz 3464 5 finden finden NNP cord-015369-72cjogxz 3464 6 sich sich NNP cord-015369-72cjogxz 3464 7 signifikante signifikante NNP cord-015369-72cjogxz 3465 1 Hinweise Hinweise NNP cord-015369-72cjogxz 3465 2 einer einer JJ cord-015369-72cjogxz 3465 3 optimierten optimierten NN cord-015369-72cjogxz 3465 4 Perfusion perfusion NN cord-015369-72cjogxz 3465 5 . . . cord-015369-72cjogxz 3466 1 Der Der NNP cord-015369-72cjogxz 3466 2 MECC MECC NNP cord-015369-72cjogxz 3466 3 - - HYPH cord-015369-72cjogxz 3466 4 Patient Patient NNP cord-015369-72cjogxz 3466 5 ist ist NNP cord-015369-72cjogxz 3466 6 postoperativ postoperativ JJ cord-015369-72cjogxz 3466 7 aktiver aktiver NNP cord-015369-72cjogxz 3466 8 , , , cord-015369-72cjogxz 3466 9 leider leider NNP cord-015369-72cjogxz 3466 10 fehlt fehlt NNP cord-015369-72cjogxz 3466 11 dazu dazu NNP cord-015369-72cjogxz 3466 12 ein ein NNP cord-015369-72cjogxz 3466 13 objektiver objektiver NN cord-015369-72cjogxz 3466 14 Parameter Parameter NNP cord-015369-72cjogxz 3466 15 . . . cord-015369-72cjogxz 3467 1 Training training NN cord-015369-72cjogxz 3467 2 surgeons surgeon NNS cord-015369-72cjogxz 3467 3 to to TO cord-015369-72cjogxz 3467 4 establish establish VB cord-015369-72cjogxz 3467 5 a a DT cord-015369-72cjogxz 3467 6 robotically robotically RB cord-015369-72cjogxz 3467 7 assisted assist VBN cord-015369-72cjogxz 3467 8 totally totally RB cord-015369-72cjogxz 3467 9 endoscopic endoscopic JJ cord-015369-72cjogxz 3467 10 coronary coronary JJ cord-015369-72cjogxz 3467 11 surgery surgery NN cord-015369-72cjogxz 3467 12 program program NN cord-015369-72cjogxz 3467 13 Background Background NNP cord-015369-72cjogxz 3467 14 . . . cord-015369-72cjogxz 3468 1 Since since IN cord-015369-72cjogxz 3468 2 ist ist NN cord-015369-72cjogxz 3468 3 introduction introduction NN cord-015369-72cjogxz 3468 4 totally totally RB cord-015369-72cjogxz 3468 5 endoscopic endoscopic JJ cord-015369-72cjogxz 3468 6 coronary coronary JJ cord-015369-72cjogxz 3468 7 surgery surgery NN cord-015369-72cjogxz 3468 8 ( ( -LRB- cord-015369-72cjogxz 3468 9 TECAB TECAB NNP cord-015369-72cjogxz 3468 10 ) ) -RRB- cord-015369-72cjogxz 3468 11 was be VBD cord-015369-72cjogxz 3468 12 standardized standardize VBN cord-015369-72cjogxz 3468 13 during during IN cord-015369-72cjogxz 3468 14 the the DT cord-015369-72cjogxz 3468 15 past past JJ cord-015369-72cjogxz 3468 16 decade decade NN cord-015369-72cjogxz 3468 17 . . . cord-015369-72cjogxz 3469 1 Additionally additionally RB cord-015369-72cjogxz 3469 2 younger young JJR cord-015369-72cjogxz 3469 3 surgeons surgeon NNS cord-015369-72cjogxz 3469 4 needed need VBD cord-015369-72cjogxz 3469 5 training training NN cord-015369-72cjogxz 3469 6 in in IN cord-015369-72cjogxz 3469 7 robotically robotically RB cord-015369-72cjogxz 3469 8 assisted assist VBN cord-015369-72cjogxz 3469 9 cardiac cardiac JJ cord-015369-72cjogxz 3469 10 surgery surgery NN cord-015369-72cjogxz 3469 11 . . . cord-015369-72cjogxz 3470 1 Methods method NNS cord-015369-72cjogxz 3470 2 . . . cord-015369-72cjogxz 3471 1 In in IN cord-015369-72cjogxz 3471 2 44 44 CD cord-015369-72cjogxz 3471 3 out out IN cord-015369-72cjogxz 3471 4 of of IN cord-015369-72cjogxz 3471 5 239 239 CD cord-015369-72cjogxz 3471 6 robotically robotically RB cord-015369-72cjogxz 3471 7 assisted assist VBD cord-015369-72cjogxz 3471 8 ( ( -LRB- cord-015369-72cjogxz 3471 9 da da NNP cord-015369-72cjogxz 3471 10 Vinci Vinci NNP cord-015369-72cjogxz 3471 11 TM TM NNP cord-015369-72cjogxz 3471 12 telemanipulator telemanipulator NN cord-015369-72cjogxz 3471 13 , , , cord-015369-72cjogxz 3471 14 Intuitive Intuitive NNP cord-015369-72cjogxz 3471 15 Inc. Inc. NNP cord-015369-72cjogxz 3471 16 , , , cord-015369-72cjogxz 3471 17 Sunnyvale Sunnyvale NNP cord-015369-72cjogxz 3471 18 , , , cord-015369-72cjogxz 3471 19 CA CA NNP cord-015369-72cjogxz 3471 20 ) ) -RRB- cord-015369-72cjogxz 3471 21 coronary coronary JJ cord-015369-72cjogxz 3471 22 operations operation NNS cord-015369-72cjogxz 3471 23 parts part NNS cord-015369-72cjogxz 3471 24 of of IN cord-015369-72cjogxz 3471 25 the the DT cord-015369-72cjogxz 3471 26 procedure procedure NN cord-015369-72cjogxz 3471 27 were be VBD cord-015369-72cjogxz 3471 28 performed perform VBN cord-015369-72cjogxz 3471 29 by by IN cord-015369-72cjogxz 3471 30 2 2 CD cord-015369-72cjogxz 3471 31 surgeons surgeon NNS cord-015369-72cjogxz 3471 32 trained train VBN cord-015369-72cjogxz 3471 33 in in IN cord-015369-72cjogxz 3471 34 endoscopic endoscopic JJ cord-015369-72cjogxz 3471 35 cardiac cardiac JJ cord-015369-72cjogxz 3471 36 surgery surgery NN cord-015369-72cjogxz 3471 37 . . . cord-015369-72cjogxz 3472 1 The the DT cord-015369-72cjogxz 3472 2 distinct distinct JJ cord-015369-72cjogxz 3472 3 parts part NNS cord-015369-72cjogxz 3472 4 of of IN cord-015369-72cjogxz 3472 5 the the DT cord-015369-72cjogxz 3472 6 TECAB TECAB NNP cord-015369-72cjogxz 3472 7 procedure procedure NN cord-015369-72cjogxz 3472 8 were be VBD cord-015369-72cjogxz 3472 9 : : : cord-015369-72cjogxz 3473 1 LIMA LIMA NNP cord-015369-72cjogxz 3473 2 / / SYM cord-015369-72cjogxz 3473 3 RIMA RIMA NNP cord-015369-72cjogxz 3473 4 preparation preparation NN cord-015369-72cjogxz 3473 5 , , , cord-015369-72cjogxz 3473 6 lipectomy lipectomy NN cord-015369-72cjogxz 3473 7 , , , cord-015369-72cjogxz 3473 8 pericardiotomy pericardiotomy NN cord-015369-72cjogxz 3473 9 , , , cord-015369-72cjogxz 3473 10 IMA IMA NNP cord-015369-72cjogxz 3473 11 to to IN cord-015369-72cjogxz 3473 12 LAD lad NN cord-015369-72cjogxz 3474 1 anastomotic anastomotic JJ cord-015369-72cjogxz 3474 2 suturing suturing NN cord-015369-72cjogxz 3474 3 . . . cord-015369-72cjogxz 3475 1 Conclusions conclusion NNS cord-015369-72cjogxz 3475 2 . . . cord-015369-72cjogxz 3476 1 We -PRON- PRP cord-015369-72cjogxz 3476 2 conclude conclude VBP cord-015369-72cjogxz 3476 3 that that IN cord-015369-72cjogxz 3476 4 the the DT cord-015369-72cjogxz 3476 5 TECAB TECAB NNP cord-015369-72cjogxz 3476 6 procedure procedure NN cord-015369-72cjogxz 3476 7 can can MD cord-015369-72cjogxz 3476 8 well well RB cord-015369-72cjogxz 3476 9 be be VB cord-015369-72cjogxz 3476 10 trained train VBN cord-015369-72cjogxz 3476 11 in in IN cord-015369-72cjogxz 3476 12 a a DT cord-015369-72cjogxz 3476 13 stepwise stepwise JJ cord-015369-72cjogxz 3476 14 approach approach NN cord-015369-72cjogxz 3476 15 . . . cord-015369-72cjogxz 3477 1 The the DT cord-015369-72cjogxz 3477 2 establishment establishment NN cord-015369-72cjogxz 3477 3 of of IN cord-015369-72cjogxz 3477 4 a a DT cord-015369-72cjogxz 3477 5 robotically robotically RB cord-015369-72cjogxz 3477 6 assisted assist VBN cord-015369-72cjogxz 3477 7 coronary coronary JJ cord-015369-72cjogxz 3477 8 surgery surgery NN cord-015369-72cjogxz 3477 9 program program NN cord-015369-72cjogxz 3477 10 is be VBZ cord-015369-72cjogxz 3477 11 feasible feasible JJ cord-015369-72cjogxz 3477 12 after after IN cord-015369-72cjogxz 3477 13 adequate adequate JJ cord-015369-72cjogxz 3477 14 training training NN cord-015369-72cjogxz 3477 15 . . . cord-015369-72cjogxz 3478 1 Obesity obesity NN cord-015369-72cjogxz 3478 2 has have VBZ cord-015369-72cjogxz 3478 3 no no DT cord-015369-72cjogxz 3478 4 effect effect NN cord-015369-72cjogxz 3478 5 on on IN cord-015369-72cjogxz 3478 6 operative operative JJ cord-015369-72cjogxz 3478 7 times time NNS cord-015369-72cjogxz 3478 8 and and CC cord-015369-72cjogxz 3478 9 perioperative perioperative JJ cord-015369-72cjogxz 3478 10 outcome outcome NN cord-015369-72cjogxz 3478 11 of of IN cord-015369-72cjogxz 3478 12 patients patient NNS cord-015369-72cjogxz 3478 13 -Undergoing -undergoe VBG cord-015369-72cjogxz 3479 1 totally totally RB cord-015369-72cjogxz 3479 2 endoscopic endoscopic JJ cord-015369-72cjogxz 3479 3 coronary coronary JJ cord-015369-72cjogxz 3479 4 artery artery NN cord-015369-72cjogxz 3479 5 bypass bypass NN cord-015369-72cjogxz 3479 6 surgery surgery NN cord-015369-72cjogxz 3479 7 Background background NN cord-015369-72cjogxz 3479 8 . . . cord-015369-72cjogxz 3480 1 More More JJR cord-015369-72cjogxz 3480 2 and and CC cord-015369-72cjogxz 3480 3 more more JJR cord-015369-72cjogxz 3480 4 patients patient NNS cord-015369-72cjogxz 3480 5 undergoing undergo VBG cord-015369-72cjogxz 3480 6 coronary coronary JJ cord-015369-72cjogxz 3480 7 artery artery NN cord-015369-72cjogxz 3480 8 bypass bypass NN cord-015369-72cjogxz 3480 9 grafting grafting NN cord-015369-72cjogxz 3480 10 ( ( -LRB- cord-015369-72cjogxz 3480 11 CABG CABG NNP cord-015369-72cjogxz 3480 12 ) ) -RRB- cord-015369-72cjogxz 3480 13 are be VBP cord-015369-72cjogxz 3480 14 overweight overweight JJ cord-015369-72cjogxz 3480 15 . . . cord-015369-72cjogxz 3481 1 Even even RB cord-015369-72cjogxz 3481 2 though though IN cord-015369-72cjogxz 3481 3 in in IN cord-015369-72cjogxz 3481 4 these these DT cord-015369-72cjogxz 3481 5 patients patient NNS cord-015369-72cjogxz 3481 6 there there EX cord-015369-72cjogxz 3481 7 is be VBZ cord-015369-72cjogxz 3481 8 no no DT cord-015369-72cjogxz 3481 9 clear clear JJ cord-015369-72cjogxz 3481 10 evidence evidence NN cord-015369-72cjogxz 3481 11 of of IN cord-015369-72cjogxz 3481 12 increased increase VBN cord-015369-72cjogxz 3481 13 perioperative perioperative JJ cord-015369-72cjogxz 3481 14 mortality mortality NN cord-015369-72cjogxz 3481 15 , , , cord-015369-72cjogxz 3481 16 it -PRON- PRP cord-015369-72cjogxz 3481 17 has have VBZ cord-015369-72cjogxz 3481 18 been be VBN cord-015369-72cjogxz 3481 19 shown show VBN cord-015369-72cjogxz 3481 20 that that IN cord-015369-72cjogxz 3481 21 they -PRON- PRP cord-015369-72cjogxz 3481 22 suffer suffer VBP cord-015369-72cjogxz 3481 23 from from IN cord-015369-72cjogxz 3481 24 superficial superficial JJ cord-015369-72cjogxz 3481 25 - - HYPH cord-015369-72cjogxz 3481 26 and and CC cord-015369-72cjogxz 3481 27 deep deep JJ cord-015369-72cjogxz 3481 28 wound wound NN cord-015369-72cjogxz 3481 29 healing healing NN cord-015369-72cjogxz 3481 30 problems problem NNS cord-015369-72cjogxz 3481 31 more more RBR cord-015369-72cjogxz 3481 32 often often RB cord-015369-72cjogxz 3481 33 than than IN cord-015369-72cjogxz 3481 34 normal normal JJ cord-015369-72cjogxz 3481 35 - - HYPH cord-015369-72cjogxz 3481 36 weight weight NN cord-015369-72cjogxz 3481 37 patients patient NNS cord-015369-72cjogxz 3481 38 . . . cord-015369-72cjogxz 3482 1 Therefore therefore RB cord-015369-72cjogxz 3482 2 , , , cord-015369-72cjogxz 3482 3 avoiding avoid VBG cord-015369-72cjogxz 3482 4 sternotomy sternotomy NN cord-015369-72cjogxz 3482 5 in in IN cord-015369-72cjogxz 3482 6 obese obese JJ cord-015369-72cjogxz 3482 7 patients patient NNS cord-015369-72cjogxz 3482 8 by by IN cord-015369-72cjogxz 3482 9 using use VBG cord-015369-72cjogxz 3482 10 an an DT cord-015369-72cjogxz 3482 11 endoscopic endoscopic JJ cord-015369-72cjogxz 3482 12 technique technique NN cord-015369-72cjogxz 3482 13 could could MD cord-015369-72cjogxz 3482 14 be be VB cord-015369-72cjogxz 3482 15 a a DT cord-015369-72cjogxz 3482 16 promising promising JJ cord-015369-72cjogxz 3482 17 approach approach NN cord-015369-72cjogxz 3482 18 . . . cord-015369-72cjogxz 3483 1 Robotic robotic JJ cord-015369-72cjogxz 3483 2 technology technology NN cord-015369-72cjogxz 3483 3 enables enable VBZ cord-015369-72cjogxz 3483 4 totally totally RB cord-015369-72cjogxz 3483 5 endoscopic endoscopic JJ cord-015369-72cjogxz 3483 6 coronary coronary JJ cord-015369-72cjogxz 3483 7 artery artery NN cord-015369-72cjogxz 3483 8 bypass bypass NN cord-015369-72cjogxz 3483 9 grafting grafting NN cord-015369-72cjogxz 3483 10 ( ( -LRB- cord-015369-72cjogxz 3483 11 TECAB TECAB NNP cord-015369-72cjogxz 3483 12 ) ) -RRB- cord-015369-72cjogxz 3483 13 procedures procedure NNS cord-015369-72cjogxz 3483 14 . . . cord-015369-72cjogxz 3484 1 We -PRON- PRP cord-015369-72cjogxz 3484 2 investigated investigate VBD cord-015369-72cjogxz 3484 3 whether whether IN cord-015369-72cjogxz 3484 4 the the DT cord-015369-72cjogxz 3484 5 intraoperative intraoperative JJ cord-015369-72cjogxz 3484 6 times time NNS cord-015369-72cjogxz 3484 7 or or CC cord-015369-72cjogxz 3484 8 perioperative perioperative JJ cord-015369-72cjogxz 3484 9 outcome outcome NN cord-015369-72cjogxz 3484 10 after after IN cord-015369-72cjogxz 3484 11 TECAB tecab NN cord-015369-72cjogxz 3484 12 - - HYPH cord-015369-72cjogxz 3484 13 procedure procedure NN cord-015369-72cjogxz 3484 14 are be VBP cord-015369-72cjogxz 3484 15 negatively negatively RB cord-015369-72cjogxz 3484 16 affected affect VBN cord-015369-72cjogxz 3484 17 by by IN cord-015369-72cjogxz 3484 18 obesity obesity NN cord-015369-72cjogxz 3484 19 . . . cord-015369-72cjogxz 3485 1 Methods method NNS cord-015369-72cjogxz 3485 2 . . . cord-015369-72cjogxz 3486 1 Patients patient NNS cord-015369-72cjogxz 3486 2 ( ( -LRB- cord-015369-72cjogxz 3486 3 n n CC cord-015369-72cjogxz 3486 4 ¼ ¼ NNP cord-015369-72cjogxz 3486 5 127 127 CD cord-015369-72cjogxz 3486 6 , , , cord-015369-72cjogxz 3486 7 101 101 CD cord-015369-72cjogxz 3486 8 male male NN cord-015369-72cjogxz 3486 9 , , , cord-015369-72cjogxz 3486 10 26 26 CD cord-015369-72cjogxz 3486 11 female female JJ cord-015369-72cjogxz 3486 12 , , , cord-015369-72cjogxz 3486 13 median median JJ cord-015369-72cjogxz 3486 14 age age NN cord-015369-72cjogxz 3486 15 59 59 CD cord-015369-72cjogxz 3486 16 ( ( -LRB- cord-015369-72cjogxz 3486 17 31 31 CD cord-015369-72cjogxz 3486 18 - - SYM cord-015369-72cjogxz 3486 19 77 77 CD cord-015369-72cjogxz 3486 20 ) ) -RRB- cord-015369-72cjogxz 3486 21 years year NNS cord-015369-72cjogxz 3486 22 ) ) -RRB- cord-015369-72cjogxz 3486 23 , , , cord-015369-72cjogxz 3486 24 undergoing undergo VBG cord-015369-72cjogxz 3486 25 arrested arrest VBN cord-015369-72cjogxz 3486 26 - - HYPH cord-015369-72cjogxz 3486 27 heart heart NN cord-015369-72cjogxz 3486 28 TECAB TECAB NNP cord-015369-72cjogxz 3486 29 procedure procedure NN cord-015369-72cjogxz 3486 30 were be VBD cord-015369-72cjogxz 3486 31 enrolled enrol VBN cord-015369-72cjogxz 3486 32 . . . cord-015369-72cjogxz 3487 1 The the DT cord-015369-72cjogxz 3487 2 median median JJ cord-015369-72cjogxz 3487 3 BMI bmi NN cord-015369-72cjogxz 3487 4 in in IN cord-015369-72cjogxz 3487 5 this this DT cord-015369-72cjogxz 3487 6 patient patient JJ cord-015369-72cjogxz 3487 7 cohort cohort NN cord-015369-72cjogxz 3487 8 was be VBD cord-015369-72cjogxz 3487 9 26(19 26(19 CD cord-015369-72cjogxz 3487 10 - - SYM cord-015369-72cjogxz 3487 11 38 38 CD cord-015369-72cjogxz 3487 12 ) ) -RRB- cord-015369-72cjogxz 3487 13 . . . cord-015369-72cjogxz 3488 1 In in IN cord-015369-72cjogxz 3488 2 detail detail NN cord-015369-72cjogxz 3488 3 , , , cord-015369-72cjogxz 3488 4 27 27 CD cord-015369-72cjogxz 3488 5 patients patient NNS cord-015369-72cjogxz 3488 6 were be VBD cord-015369-72cjogxz 3488 7 normalweight(BMI normalweight(BMI NNP cord-015369-72cjogxz 3488 8 25 25 CD cord-015369-72cjogxz 3488 9 kg kg NN cord-015369-72cjogxz 3488 10 / / SYM cord-015369-72cjogxz 3488 11 m m NN cord-015369-72cjogxz 3488 12 2 2 CD cord-015369-72cjogxz 3488 13 ) ) -RRB- cord-015369-72cjogxz 3488 14 , , , cord-015369-72cjogxz 3488 15 67 67 CD cord-015369-72cjogxz 3488 16 Patients patient NNS cord-015369-72cjogxz 3488 17 were be VBD cord-015369-72cjogxz 3488 18 overweight(BMI:25.1 overweight(BMI:25.1 NNS cord-015369-72cjogxz 3488 19 - - : cord-015369-72cjogxz 3488 20 30 30 CD cord-015369-72cjogxz 3488 21 kg kg NN cord-015369-72cjogxz 3488 22 / / SYM cord-015369-72cjogxz 3488 23 m m NN cord-015369-72cjogxz 3488 24 2 2 CD cord-015369-72cjogxz 3488 25 ) ) -RRB- cord-015369-72cjogxz 3488 26 , , , cord-015369-72cjogxz 3488 27 29 29 CD cord-015369-72cjogxz 3488 28 patients patient NNS cord-015369-72cjogxz 3488 29 were be VBD cord-015369-72cjogxz 3488 30 obese obese JJ cord-015369-72cjogxz 3488 31 ( ( -LRB- cord-015369-72cjogxz 3488 32 BMI BMI NNP cord-015369-72cjogxz 3488 33 30.1 30.1 CD cord-015369-72cjogxz 3488 34 - - HYPH cord-015369-72cjogxz 3488 35 33.9 33.9 CD cord-015369-72cjogxz 3488 36 kg kg NNP cord-015369-72cjogxz 3488 37 / / SYM cord-015369-72cjogxz 3488 38 m m NN cord-015369-72cjogxz 3488 39 2 2 CD cord-015369-72cjogxz 3488 40 ) ) -RRB- cord-015369-72cjogxz 3488 41 and and CC cord-015369-72cjogxz 3488 42 4 4 CD cord-015369-72cjogxz 3488 43 patients patient NNS cord-015369-72cjogxz 3488 44 were be VBD cord-015369-72cjogxz 3488 45 morbidly morbidly RB cord-015369-72cjogxz 3488 46 obese obese JJ cord-015369-72cjogxz 3488 47 ( ( -LRB- cord-015369-72cjogxz 3488 48 BMI BMI NNP cord-015369-72cjogxz 3488 49 ! ! . cord-015369-72cjogxz 3488 50 34 34 CD cord-015369-72cjogxz 3488 51 kg kg NN cord-015369-72cjogxz 3488 52 / / SYM cord-015369-72cjogxz 3488 53 m m NN cord-015369-72cjogxz 3488 54 2 2 CD cord-015369-72cjogxz 3488 55 ) ) -RRB- cord-015369-72cjogxz 3488 56 . . . cord-015369-72cjogxz 3489 1 The the DT cord-015369-72cjogxz 3489 2 Heartport Heartport NNP cord-015369-72cjogxz 3489 3 / / SYM cord-015369-72cjogxz 3489 4 Cardiovations Cardiovations NNP cord-015369-72cjogxz 3489 5 TM TM NNP cord-015369-72cjogxz 3489 6 ( ( -LRB- cord-015369-72cjogxz 3489 7 n n NN cord-015369-72cjogxz 3489 8 ¼ ¼ NNP cord-015369-72cjogxz 3489 9 44 44 CD cord-015369-72cjogxz 3489 10 ) ) -RRB- cord-015369-72cjogxz 3489 11 or or CC cord-015369-72cjogxz 3489 12 the the DT cord-015369-72cjogxz 3489 13 ESTECH ESTECH NNP cord-015369-72cjogxz 3489 14 - - HYPH cord-015369-72cjogxz 3489 15 RAP rap NN cord-015369-72cjogxz 3489 16 TM TM NNP cord-015369-72cjogxz 3489 17 system system NN cord-015369-72cjogxz 3489 18 ( ( -LRB- cord-015369-72cjogxz 3489 19 n n NNP cord-015369-72cjogxz 3489 20 ¼ ¼ NNP cord-015369-72cjogxz 3489 21 83 83 CD cord-015369-72cjogxz 3489 22 ) ) -RRB- cord-015369-72cjogxz 3489 23 were be VBD cord-015369-72cjogxz 3489 24 used use VBN cord-015369-72cjogxz 3489 25 for for IN cord-015369-72cjogxz 3489 26 arrested arrest VBN cord-015369-72cjogxz 3489 27 heart heart NN cord-015369-72cjogxz 3489 28 TECAB TECAB NNP cord-015369-72cjogxz 3489 29 procedure procedure NN cord-015369-72cjogxz 3489 30 with with IN cord-015369-72cjogxz 3489 31 remote remote JJ cord-015369-72cjogxz 3489 32 access access NN cord-015369-72cjogxz 3489 33 perfusion perfusion NN cord-015369-72cjogxz 3489 34 and and CC cord-015369-72cjogxz 3489 35 aortic aortic JJ cord-015369-72cjogxz 3489 36 - - HYPH cord-015369-72cjogxz 3489 37 endoocclusion endoocclusion NN cord-015369-72cjogxz 3489 38 . . . cord-015369-72cjogxz 3490 1 Results result NNS cord-015369-72cjogxz 3490 2 . . . cord-015369-72cjogxz 3491 1 There there EX cord-015369-72cjogxz 3491 2 was be VBD cord-015369-72cjogxz 3491 3 no no DT cord-015369-72cjogxz 3491 4 correlation correlation NN cord-015369-72cjogxz 3491 5 between between IN cord-015369-72cjogxz 3491 6 BMI BMI NNP cord-015369-72cjogxz 3491 7 ( ( -LRB- cord-015369-72cjogxz 3491 8 1 1 CD cord-015369-72cjogxz 3491 9 ) ) -RRB- cord-015369-72cjogxz 3491 10 left leave VBN cord-015369-72cjogxz 3491 11 internal internal JJ cord-015369-72cjogxz 3491 12 - - HYPH cord-015369-72cjogxz 3491 13 mammary mammary JJ cord-015369-72cjogxz 3491 14 - - HYPH cord-015369-72cjogxz 3491 15 artery artery NN cord-015369-72cjogxz 3491 16 - - HYPH cord-015369-72cjogxz 3491 17 takedown takedown NN cord-015369-72cjogxz 3491 18 - - HYPH cord-015369-72cjogxz 3491 19 time(R time(r NN cord-015369-72cjogxz 3492 1 ¼ ¼ NNP cord-015369-72cjogxz 3492 2 0.2 0.2 CD cord-015369-72cjogxz 3492 3 ; ; : cord-015369-72cjogxz 3492 4 p p NN cord-015369-72cjogxz 3492 5 ¼ ¼ NNP cord-015369-72cjogxz 3492 6 n.s n.s NNP cord-015369-72cjogxz 3492 7 . . NNP cord-015369-72cjogxz 3492 8 ) ) -RRB- cord-015369-72cjogxz 3493 1 , , , cord-015369-72cjogxz 3493 2 ( ( -LRB- cord-015369-72cjogxz 3493 3 2 2 LS cord-015369-72cjogxz 3493 4 ) ) -RRB- cord-015369-72cjogxz 3493 5 lipectomy lipectomy NN cord-015369-72cjogxz 3493 6 and and CC cord-015369-72cjogxz 3493 7 pericardiotomy pericardiotomy NN cord-015369-72cjogxz 3493 8 - - HYPH cord-015369-72cjogxz 3493 9 time time NN cord-015369-72cjogxz 3494 1 ( ( -LRB- cord-015369-72cjogxz 3494 2 R R NNP cord-015369-72cjogxz 3494 3 ¼ ¼ NNP cord-015369-72cjogxz 3494 4 0.042 0.042 CD cord-015369-72cjogxz 3494 5 , , , cord-015369-72cjogxz 3494 6 p p NNP cord-015369-72cjogxz 3494 7 ¼ ¼ NNP cord-015369-72cjogxz 3494 8 n.s n.s NNP cord-015369-72cjogxz 3494 9 . . NNP cord-015369-72cjogxz 3494 10 ) ) -RRB- cord-015369-72cjogxz 3495 1 ( ( -LRB- cord-015369-72cjogxz 3495 2 3 3 LS cord-015369-72cjogxz 3495 3 ) ) -RRB- cord-015369-72cjogxz 3495 4 total total JJ cord-015369-72cjogxz 3495 5 operative operative JJ cord-015369-72cjogxz 3495 6 - - HYPH cord-015369-72cjogxz 3495 7 time time NN cord-015369-72cjogxz 3495 8 ( ( -LRB- cord-015369-72cjogxz 3495 9 R r NN cord-015369-72cjogxz 3495 10 ¼ ¼ NN cord-015369-72cjogxz 3495 11 À à NN cord-015369-72cjogxz 3495 12 0.83 0.83 CD cord-015369-72cjogxz 3495 13 : : : cord-015369-72cjogxz 3495 14 p p NN cord-015369-72cjogxz 3495 15 ¼ ¼ NNP cord-015369-72cjogxz 3495 16 n.s n.s NNP cord-015369-72cjogxz 3495 17 . . NNP cord-015369-72cjogxz 3495 18 ) ) -RRB- cord-015369-72cjogxz 3495 19 , , , cord-015369-72cjogxz 3495 20 ( ( -LRB- cord-015369-72cjogxz 3495 21 4 4 LS cord-015369-72cjogxz 3495 22 ) ) -RRB- cord-015369-72cjogxz 3495 23 cardiopulmonary cardiopulmonary JJ cord-015369-72cjogxz 3495 24 - - HYPH cord-015369-72cjogxz 3495 25 bypass bypass NN cord-015369-72cjogxz 3495 26 - - HYPH cord-015369-72cjogxz 3495 27 time time NN cord-015369-72cjogxz 3495 28 ( ( -LRB- cord-015369-72cjogxz 3495 29 R r NN cord-015369-72cjogxz 3495 30 ¼ ¼ NN cord-015369-72cjogxz 3495 31 À à NN cord-015369-72cjogxz 3495 32 0.12 0.12 CD cord-015369-72cjogxz 3495 33 ; ; : cord-015369-72cjogxz 3495 34 p p NN cord-015369-72cjogxz 3495 35 ¼ ¼ NNP cord-015369-72cjogxz 3495 36 n.s n.s NNP cord-015369-72cjogxz 3495 37 . . NNP cord-015369-72cjogxz 3495 38 ) ) -RRB- cord-015369-72cjogxz 3495 39 , , , cord-015369-72cjogxz 3495 40 ( ( -LRB- cord-015369-72cjogxz 3495 41 5 5 LS cord-015369-72cjogxz 3495 42 ) ) -RRB- cord-015369-72cjogxz 3495 43 aortic aortic JJ cord-015369-72cjogxz 3495 44 - - HYPH cord-015369-72cjogxz 3495 45 endoocclusiontime endoocclusiontime NN cord-015369-72cjogxz 3495 46 ( ( -LRB- cord-015369-72cjogxz 3495 47 R r NN cord-015369-72cjogxz 3495 48 ¼ ¼ NN cord-015369-72cjogxz 3495 49 À à NN cord-015369-72cjogxz 3495 50 0.55 0.55 CD cord-015369-72cjogxz 3495 51 ; ; : cord-015369-72cjogxz 3495 52 p p NN cord-015369-72cjogxz 3495 53 ¼ ¼ NNP cord-015369-72cjogxz 3495 54 n.s n.s NNP cord-015369-72cjogxz 3495 55 . . NNP cord-015369-72cjogxz 3495 56 ) ) -RRB- cord-015369-72cjogxz 3495 57 , , , cord-015369-72cjogxz 3495 58 ( ( -LRB- cord-015369-72cjogxz 3495 59 6 6 CD cord-015369-72cjogxz 3495 60 ) ) -RRB- cord-015369-72cjogxz 3495 61 mechanical mechanical JJ cord-015369-72cjogxz 3495 62 - - HYPH cord-015369-72cjogxz 3495 63 ventilation ventilation NN cord-015369-72cjogxz 3495 64 - - HYPH cord-015369-72cjogxz 3495 65 time time NN cord-015369-72cjogxz 3495 66 ( ( -LRB- cord-015369-72cjogxz 3495 67 R r NN cord-015369-72cjogxz 3495 68 ¼ ¼ CD cord-015369-72cjogxz 3495 69 0.001 0.001 CD cord-015369-72cjogxz 3495 70 , , , cord-015369-72cjogxz 3495 71 p p NNP cord-015369-72cjogxz 3495 72 ¼ ¼ NNP cord-015369-72cjogxz 3495 73 n.s n.s NNP cord-015369-72cjogxz 3495 74 . . NNP cord-015369-72cjogxz 3495 75 ) ) -RRB- cord-015369-72cjogxz 3496 1 ( ( -LRB- cord-015369-72cjogxz 3496 2 7 7 CD cord-015369-72cjogxz 3496 3 ) ) -RRB- cord-015369-72cjogxz 3496 4 length length NN cord-015369-72cjogxz 3496 5 of of IN cord-015369-72cjogxz 3496 6 ICUstay icustay NN cord-015369-72cjogxz 3496 7 ( ( -LRB- cord-015369-72cjogxz 3496 8 R¼ r¼ IN cord-015369-72cjogxz 3496 9 0.4 0.4 CD cord-015369-72cjogxz 3496 10 ; ; : cord-015369-72cjogxz 3496 11 p p NN cord-015369-72cjogxz 3496 12 ¼ ¼ NNP cord-015369-72cjogxz 3496 13 n.s n.s NNP cord-015369-72cjogxz 3496 14 . . NNP cord-015369-72cjogxz 3496 15 ) ) -RRB- cord-015369-72cjogxz 3496 16 , , , cord-015369-72cjogxz 3496 17 ( ( -LRB- cord-015369-72cjogxz 3496 18 8) 8) NNP cord-015369-72cjogxz 3496 19 length length NN cord-015369-72cjogxz 3496 20 of of IN cord-015369-72cjogxz 3496 21 hospital hospital NN cord-015369-72cjogxz 3496 22 - - HYPH cord-015369-72cjogxz 3496 23 stay stay NN cord-015369-72cjogxz 3496 24 ( ( -LRB- cord-015369-72cjogxz 3496 25 R r NN cord-015369-72cjogxz 3496 26 ¼ ¼ CD cord-015369-72cjogxz 3496 27 0.103 0.103 CD cord-015369-72cjogxz 3496 28 ; ; : cord-015369-72cjogxz 3497 1 p p NNP cord-015369-72cjogxz 3497 2 ¼ ¼ NNP cord-015369-72cjogxz 3497 3 n.s n.s NNP cord-015369-72cjogxz 3497 4 . . NNP cord-015369-72cjogxz 3497 5 ) ) -RRB- cord-015369-72cjogxz 3497 6 . . . cord-015369-72cjogxz 3498 1 or or CC cord-015369-72cjogxz 3498 2 ( ( -LRB- cord-015369-72cjogxz 3498 3 9 9 LS cord-015369-72cjogxz 3498 4 ) ) -RRB- cord-015369-72cjogxz 3498 5 occurrence occurrence NN cord-015369-72cjogxz 3498 6 of of IN cord-015369-72cjogxz 3498 7 intraand/ intraand/ CD cord-015369-72cjogxz 3498 8 or or CC cord-015369-72cjogxz 3498 9 postoperative postoperative JJ cord-015369-72cjogxz 3498 10 adverse adverse JJ cord-015369-72cjogxz 3498 11 events event NNS cord-015369-72cjogxz 3498 12 . . . cord-015369-72cjogxz 3499 1 Conclusions conclusion NNS cord-015369-72cjogxz 3499 2 . . . cord-015369-72cjogxz 3500 1 In in IN cord-015369-72cjogxz 3500 2 overweight overweight JJ cord-015369-72cjogxz 3500 3 , , , cord-015369-72cjogxz 3500 4 obese obese JJ cord-015369-72cjogxz 3500 5 but but CC cord-015369-72cjogxz 3500 6 also also RB cord-015369-72cjogxz 3500 7 morbidly morbidly RB cord-015369-72cjogxz 3500 8 obese obese JJ cord-015369-72cjogxz 3500 9 patients patient NNS cord-015369-72cjogxz 3500 10 the the DT cord-015369-72cjogxz 3500 11 TECAB TECAB NNP cord-015369-72cjogxz 3500 12 procedure procedure NN cord-015369-72cjogxz 3500 13 did do VBD cord-015369-72cjogxz 3500 14 not not RB cord-015369-72cjogxz 3500 15 increase increase VB cord-015369-72cjogxz 3500 16 operative operative JJ cord-015369-72cjogxz 3500 17 times time NNS cord-015369-72cjogxz 3500 18 or or CC cord-015369-72cjogxz 3500 19 the the DT cord-015369-72cjogxz 3500 20 rate rate NN cord-015369-72cjogxz 3500 21 of of IN cord-015369-72cjogxz 3500 22 intra intra JJ cord-015369-72cjogxz 3500 23 - - JJ cord-015369-72cjogxz 3500 24 or or CC cord-015369-72cjogxz 3500 25 postoperative postoperative JJ cord-015369-72cjogxz 3500 26 complications complication NNS cord-015369-72cjogxz 3500 27 . . . cord-015369-72cjogxz 3501 1 This this DT cord-015369-72cjogxz 3501 2 patient patient NN cord-015369-72cjogxz 3501 3 groups group NNS cord-015369-72cjogxz 3501 4 , , , cord-015369-72cjogxz 3501 5 therefore therefore RB cord-015369-72cjogxz 3501 6 , , , cord-015369-72cjogxz 3501 7 benefits benefit NNS cord-015369-72cjogxz 3501 8 from from IN cord-015369-72cjogxz 3501 9 this this DT cord-015369-72cjogxz 3501 10 less less RBR cord-015369-72cjogxz 3501 11 traumatic traumatic JJ cord-015369-72cjogxz 3501 12 version version NN cord-015369-72cjogxz 3501 13 of of IN cord-015369-72cjogxz 3501 14 coronary coronary JJ cord-015369-72cjogxz 3501 15 surgery surgery NN cord-015369-72cjogxz 3501 16 . . . cord-015369-72cjogxz 3502 1 Background background NN cord-015369-72cjogxz 3502 2 . . . cord-015369-72cjogxz 3503 1 Selective selective JJ cord-015369-72cjogxz 3503 2 decontamination decontamination NN cord-015369-72cjogxz 3503 3 of of IN cord-015369-72cjogxz 3503 4 the the DT cord-015369-72cjogxz 3503 5 digestive digestive JJ cord-015369-72cjogxz 3503 6 tract tract NN cord-015369-72cjogxz 3503 7 is be VBZ cord-015369-72cjogxz 3503 8 still still RB cord-015369-72cjogxz 3503 9 not not RB cord-015369-72cjogxz 3503 10 widely widely RB cord-015369-72cjogxz 3503 11 accepted accept VBN cord-015369-72cjogxz 3503 12 , , , cord-015369-72cjogxz 3503 13 although although IN cord-015369-72cjogxz 3503 14 it -PRON- PRP cord-015369-72cjogxz 3503 15 reduces reduce VBZ cord-015369-72cjogxz 3503 16 the the DT cord-015369-72cjogxz 3503 17 incidence incidence NN cord-015369-72cjogxz 3503 18 of of IN cord-015369-72cjogxz 3503 19 nosocomial nosocomial JJ cord-015369-72cjogxz 3503 20 infections infection NNS cord-015369-72cjogxz 3503 21 . . . cord-015369-72cjogxz 3504 1 In in IN cord-015369-72cjogxz 3504 2 a a DT cord-015369-72cjogxz 3504 3 previous previous JJ cord-015369-72cjogxz 3504 4 retrospective retrospective JJ cord-015369-72cjogxz 3504 5 study study NN cord-015369-72cjogxz 3504 6 we -PRON- PRP cord-015369-72cjogxz 3504 7 have have VBP cord-015369-72cjogxz 3504 8 shown show VBN cord-015369-72cjogxz 3504 9 a a DT cord-015369-72cjogxz 3504 10 clear clear JJ cord-015369-72cjogxz 3504 11 reduction reduction NN cord-015369-72cjogxz 3504 12 of of IN cord-015369-72cjogxz 3504 13 nosocomial nosocomial JJ cord-015369-72cjogxz 3504 14 infections infection NNS cord-015369-72cjogxz 3504 15 in in IN cord-015369-72cjogxz 3504 16 patients patient NNS cord-015369-72cjogxz 3504 17 with with IN cord-015369-72cjogxz 3504 18 esophageal esophageal JJ cord-015369-72cjogxz 3504 19 anastomoses anastomosis NNS cord-015369-72cjogxz 3504 20 receiving receive VBG cord-015369-72cjogxz 3504 21 selective selective JJ cord-015369-72cjogxz 3504 22 decontamination decontamination NN cord-015369-72cjogxz 3504 23 . . . cord-015369-72cjogxz 3505 1 We -PRON- PRP cord-015369-72cjogxz 3505 2 thus thus RB cord-015369-72cjogxz 3505 3 started start VBD cord-015369-72cjogxz 3505 4 to to TO cord-015369-72cjogxz 3505 5 apply apply VB cord-015369-72cjogxz 3505 6 selective selective JJ cord-015369-72cjogxz 3505 7 decontamination decontamination NN cord-015369-72cjogxz 3505 8 routinely routinely RB cord-015369-72cjogxz 3505 9 for for IN cord-015369-72cjogxz 3505 10 esophageal esophageal JJ cord-015369-72cjogxz 3505 11 anastomoses anastomosis NNS cord-015369-72cjogxz 3505 12 . . . cord-015369-72cjogxz 3506 1 Here here RB cord-015369-72cjogxz 3506 2 we -PRON- PRP cord-015369-72cjogxz 3506 3 report report VBP cord-015369-72cjogxz 3506 4 the the DT cord-015369-72cjogxz 3506 5 outcome outcome NN cord-015369-72cjogxz 3506 6 of of IN cord-015369-72cjogxz 3506 7 a a DT cord-015369-72cjogxz 3506 8 case case NN cord-015369-72cjogxz 3506 9 series series NN cord-015369-72cjogxz 3506 10 of of IN cord-015369-72cjogxz 3506 11 107 107 CD cord-015369-72cjogxz 3506 12 patients patient NNS cord-015369-72cjogxz 3506 13 receiving receive VBG cord-015369-72cjogxz 3506 14 this this DT cord-015369-72cjogxz 3506 15 treatment treatment NN cord-015369-72cjogxz 3506 16 and and CC cord-015369-72cjogxz 3506 17 compared compare VBD cord-015369-72cjogxz 3506 18 them -PRON- PRP cord-015369-72cjogxz 3506 19 to to IN cord-015369-72cjogxz 3506 20 historic historic JJ cord-015369-72cjogxz 3506 21 controls control NNS cord-015369-72cjogxz 3506 22 . . . cord-015369-72cjogxz 3507 1 Methods method NNS cord-015369-72cjogxz 3507 2 . . . cord-015369-72cjogxz 3508 1 From from IN cord-015369-72cjogxz 3508 2 2002 2002 CD cord-015369-72cjogxz 3508 3 , , , cord-015369-72cjogxz 3508 4 patients patient NNS cord-015369-72cjogxz 3508 5 with with IN cord-015369-72cjogxz 3508 6 esophageal esophageal JJ cord-015369-72cjogxz 3508 7 anastomosis anastomosis NN cord-015369-72cjogxz 3508 8 were be VBD cord-015369-72cjogxz 3508 9 prospectively prospectively RB cord-015369-72cjogxz 3508 10 registered register VBN cord-015369-72cjogxz 3508 11 . . . cord-015369-72cjogxz 3509 1 Patients patient NNS cord-015369-72cjogxz 3509 2 received receive VBD cord-015369-72cjogxz 3509 3 polymyxin polymyxin NN cord-015369-72cjogxz 3509 4 , , , cord-015369-72cjogxz 3509 5 tobramyxin tobramyxin NNP cord-015369-72cjogxz 3509 6 , , , cord-015369-72cjogxz 3509 7 vancomycin vancomycin FW cord-015369-72cjogxz 3509 8 ( ( -LRB- cord-015369-72cjogxz 3509 9 PTV PTV NNP cord-015369-72cjogxz 3509 10 ) ) -RRB- cord-015369-72cjogxz 3509 11 and and CC cord-015369-72cjogxz 3509 12 mycostatine mycostatine NNP cord-015369-72cjogxz 3509 13 four four CD cord-015369-72cjogxz 3509 14 times time NNS cord-015369-72cjogxz 3509 15 a a DT cord-015369-72cjogxz 3509 16 day day NN cord-015369-72cjogxz 3509 17 orally orally RB cord-015369-72cjogxz 3509 18 on on IN cord-015369-72cjogxz 3509 19 average average NN cord-015369-72cjogxz 3509 20 for for IN cord-015369-72cjogxz 3509 21 8 8 CD cord-015369-72cjogxz 3509 22 days day NNS cord-015369-72cjogxz 3509 23 starting start VBG cord-015369-72cjogxz 3509 24 on on IN cord-015369-72cjogxz 3509 25 the the DT cord-015369-72cjogxz 3509 26 day day NN cord-015369-72cjogxz 3509 27 before before IN cord-015369-72cjogxz 3509 28 surgery surgery NN cord-015369-72cjogxz 3509 29 . . . cord-015369-72cjogxz 3510 1 Outcome outcome NN cord-015369-72cjogxz 3510 2 was be VBD cord-015369-72cjogxz 3510 3 compared compare VBN cord-015369-72cjogxz 3510 4 to to IN cord-015369-72cjogxz 3510 5 a a DT cord-015369-72cjogxz 3510 6 historic historic JJ cord-015369-72cjogxz 3510 7 control control NN cord-015369-72cjogxz 3510 8 treated treat VBN cord-015369-72cjogxz 3510 9 before before IN cord-015369-72cjogxz 3510 10 2002 2002 CD cord-015369-72cjogxz 3510 11 without without IN cord-015369-72cjogxz 3510 12 selective selective JJ cord-015369-72cjogxz 3510 13 decontamination decontamination NN cord-015369-72cjogxz 3510 14 ( ( -LRB- cord-015369-72cjogxz 3510 15 n n NN cord-015369-72cjogxz 3510 16 ¼ ¼ NNP cord-015369-72cjogxz 3510 17 69 69 CD cord-015369-72cjogxz 3510 18 ) ) -RRB- cord-015369-72cjogxz 3510 19 , , , cord-015369-72cjogxz 3510 20 which which WDT cord-015369-72cjogxz 3510 21 did do VBD cord-015369-72cjogxz 3510 22 not not RB cord-015369-72cjogxz 3510 23 differ differ VB cord-015369-72cjogxz 3510 24 significantly significantly RB cord-015369-72cjogxz 3510 25 in in IN cord-015369-72cjogxz 3510 26 age age NN cord-015369-72cjogxz 3510 27 , , , cord-015369-72cjogxz 3510 28 gender gender NN cord-015369-72cjogxz 3510 29 , , , cord-015369-72cjogxz 3510 30 BMI BMI NNP cord-015369-72cjogxz 3510 31 and and CC cord-015369-72cjogxz 3510 32 ASA ASA NNP cord-015369-72cjogxz 3510 33 score score NN cord-015369-72cjogxz 3510 34 . . . cord-015369-72cjogxz 3511 1 Results result NNS cord-015369-72cjogxz 3511 2 . . . cord-015369-72cjogxz 3512 1 A a DT cord-015369-72cjogxz 3512 2 total total NN cord-015369-72cjogxz 3512 3 of of IN cord-015369-72cjogxz 3512 4 107 107 CD cord-015369-72cjogxz 3512 5 patients patient NNS cord-015369-72cjogxz 3512 6 received receive VBD cord-015369-72cjogxz 3512 7 selective selective JJ cord-015369-72cjogxz 3512 8 decontamination decontamination NN cord-015369-72cjogxz 3512 9 . . . cord-015369-72cjogxz 3513 1 The the DT cord-015369-72cjogxz 3513 2 average average JJ cord-015369-72cjogxz 3513 3 age age NN cord-015369-72cjogxz 3513 4 was be VBD cord-015369-72cjogxz 3513 5 62.4 62.4 CD cord-015369-72cjogxz 3513 6 years year NNS cord-015369-72cjogxz 3513 7 and and CC cord-015369-72cjogxz 3513 8 ASA ASA NNP cord-015369-72cjogxz 3513 9 score score NN cord-015369-72cjogxz 3513 10 was be VBD cord-015369-72cjogxz 3513 11 2 2 CD cord-015369-72cjogxz 3513 12 . . . cord-015369-72cjogxz 3514 1 The the DT cord-015369-72cjogxz 3514 2 pulmonary pulmonary JJ cord-015369-72cjogxz 3514 3 infection infection NN cord-015369-72cjogxz 3514 4 rate rate NN cord-015369-72cjogxz 3514 5 was be VBD cord-015369-72cjogxz 3514 6 6.5 6.5 CD cord-015369-72cjogxz 3514 7 % % NN cord-015369-72cjogxz 3514 8 ( ( -LRB- cord-015369-72cjogxz 3514 9 95 95 CD cord-015369-72cjogxz 3514 10 % % NN cord-015369-72cjogxz 3514 11 CI ci NN cord-015369-72cjogxz 3514 12 : : : cord-015369-72cjogxz 3514 13 3.2 3.2 CD cord-015369-72cjogxz 3514 14 - - HYPH cord-015369-72cjogxz 3514 15 12.9 12.9 CD cord-015369-72cjogxz 3514 16 % % NN cord-015369-72cjogxz 3514 17 ) ) -RRB- cord-015369-72cjogxz 3514 18 clearly clearly RB cord-015369-72cjogxz 3514 19 lower low JJR cord-015369-72cjogxz 3514 20 than than IN cord-015369-72cjogxz 3514 21 in in IN cord-015369-72cjogxz 3514 22 the the DT cord-015369-72cjogxz 3514 23 historic historic JJ cord-015369-72cjogxz 3514 24 control control NN cord-015369-72cjogxz 3514 25 ( ( -LRB- cord-015369-72cjogxz 3514 26 24.6 24.6 CD cord-015369-72cjogxz 3514 27 % % NN cord-015369-72cjogxz 3514 28 , , , cord-015369-72cjogxz 3514 29 95 95 CD cord-015369-72cjogxz 3514 30 % % NN cord-015369-72cjogxz 3514 31 CI ci NN cord-015369-72cjogxz 3514 32 : : : cord-015369-72cjogxz 3514 33 16.0 16.0 CD cord-015369-72cjogxz 3514 34 - - HYPH cord-015369-72cjogxz 3514 35 35.0 35.0 CD cord-015369-72cjogxz 3514 36 % % NN cord-015369-72cjogxz 3514 37 , , , cord-015369-72cjogxz 3514 38 p p NN cord-015369-72cjogxz 3514 39 ¼ ¼ CD cord-015369-72cjogxz 3514 40 0.0012 0.0012 CD cord-015369-72cjogxz 3514 41 ) ) -RRB- cord-015369-72cjogxz 3514 42 . . . cord-015369-72cjogxz 3515 1 Anastomotic anastomotic JJ cord-015369-72cjogxz 3515 2 leakage leakage NN cord-015369-72cjogxz 3515 3 rate rate NN cord-015369-72cjogxz 3515 4 was be VBD cord-015369-72cjogxz 3515 5 6.5 6.5 CD cord-015369-72cjogxz 3515 6 % % NN cord-015369-72cjogxz 3515 7 ( ( -LRB- cord-015369-72cjogxz 3515 8 95 95 CD cord-015369-72cjogxz 3515 9 % % NN cord-015369-72cjogxz 3515 10 CI ci NN cord-015369-72cjogxz 3515 11 : : : cord-015369-72cjogxz 3515 12 3.2 3.2 CD cord-015369-72cjogxz 3515 13 - - HYPH cord-015369-72cjogxz 3515 14 12.9 12.9 CD cord-015369-72cjogxz 3515 15 % % NN cord-015369-72cjogxz 3515 16 ) ) -RRB- cord-015369-72cjogxz 3515 17 compared compare VBN cord-015369-72cjogxz 3515 18 to to IN cord-015369-72cjogxz 3515 19 13.0 13.0 CD cord-015369-72cjogxz 3515 20 % % NN cord-015369-72cjogxz 3515 21 ( ( -LRB- cord-015369-72cjogxz 3515 22 95 95 CD cord-015369-72cjogxz 3515 23 % % NN cord-015369-72cjogxz 3515 24 CI ci NN cord-015369-72cjogxz 3515 25 : : : cord-015369-72cjogxz 3515 26 7.0 7.0 CD cord-015369-72cjogxz 3515 27 - - SYM cord-015369-72cjogxz 3515 28 23.0 23.0 CD cord-015369-72cjogxz 3515 29 % % NN cord-015369-72cjogxz 3515 30 , , , cord-015369-72cjogxz 3515 31 p p NN cord-015369-72cjogxz 3515 32 ¼ ¼ CD cord-015369-72cjogxz 3515 33 0.18 0.18 CD cord-015369-72cjogxz 3515 34 ) ) -RRB- cord-015369-72cjogxz 3515 35 without without IN cord-015369-72cjogxz 3515 36 selective selective JJ cord-015369-72cjogxz 3515 37 decontamination decontamination NN cord-015369-72cjogxz 3515 38 . . . cord-015369-72cjogxz 3516 1 The the DT cord-015369-72cjogxz 3516 2 perioperative perioperative JJ cord-015369-72cjogxz 3516 3 mortality mortality NN cord-015369-72cjogxz 3516 4 was be VBD cord-015369-72cjogxz 3516 5 only only RB cord-015369-72cjogxz 3516 6 1.9 1.9 CD cord-015369-72cjogxz 3516 7 % % NN cord-015369-72cjogxz 3516 8 ( ( -LRB- cord-015369-72cjogxz 3516 9 95 95 CD cord-015369-72cjogxz 3516 10 % % NN cord-015369-72cjogxz 3516 11 CI:0.5 ci:0.5 NN cord-015369-72cjogxz 3516 12 - - HYPH cord-015369-72cjogxz 3516 13 6.6 6.6 CD cord-015369-72cjogxz 3516 14 % % NN cord-015369-72cjogxz 3516 15 ) ) -RRB- cord-015369-72cjogxz 3516 16 compared compare VBN cord-015369-72cjogxz 3516 17 to to IN cord-015369-72cjogxz 3516 18 12 12 CD cord-015369-72cjogxz 3516 19 % % NN cord-015369-72cjogxz 3516 20 ( ( -LRB- cord-015369-72cjogxz 3516 21 6.0 6.0 CD cord-015369-72cjogxz 3516 22 - - SYM cord-015369-72cjogxz 3516 23 21.3 21.3 CD cord-015369-72cjogxz 3516 24 % % NN cord-015369-72cjogxz 3516 25 , , , cord-015369-72cjogxz 3516 26 p p NN cord-015369-72cjogxz 3516 27 ¼ ¼ CD cord-015369-72cjogxz 3516 28 0.015 0.015 CD cord-015369-72cjogxz 3516 29 ) ) -RRB- cord-015369-72cjogxz 3516 30 previously previously RB cord-015369-72cjogxz 3516 31 . . . cord-015369-72cjogxz 3517 1 Conclusions conclusion NNS cord-015369-72cjogxz 3517 2 . . . cord-015369-72cjogxz 3518 1 Selective selective JJ cord-015369-72cjogxz 3518 2 decontamination decontamination NN cord-015369-72cjogxz 3518 3 of of IN cord-015369-72cjogxz 3518 4 the the DT cord-015369-72cjogxz 3518 5 digestive digestive JJ cord-015369-72cjogxz 3518 6 tract tract NN cord-015369-72cjogxz 3518 7 significantly significantly RB cord-015369-72cjogxz 3518 8 reduces reduce VBZ cord-015369-72cjogxz 3518 9 perioperative perioperative JJ cord-015369-72cjogxz 3518 10 morbidity morbidity NN cord-015369-72cjogxz 3518 11 and and CC cord-015369-72cjogxz 3518 12 mortality mortality NN cord-015369-72cjogxz 3518 13 in in IN cord-015369-72cjogxz 3518 14 patients patient NNS cord-015369-72cjogxz 3518 15 with with IN cord-015369-72cjogxz 3518 16 esophageal esophageal JJ cord-015369-72cjogxz 3518 17 anastomosis anastomosis NN cord-015369-72cjogxz 3518 18 . . . cord-015369-72cjogxz 3519 1 Anastomotic anastomotic JJ cord-015369-72cjogxz 3519 2 leakage leakage NN cord-015369-72cjogxz 3519 3 rate rate NN cord-015369-72cjogxz 3519 4 could could MD cord-015369-72cjogxz 3519 5 be be VB cord-015369-72cjogxz 3519 6 reduced reduce VBN cord-015369-72cjogxz 3519 7 resulting result VBG cord-015369-72cjogxz 3519 8 in in IN cord-015369-72cjogxz 3519 9 a a DT cord-015369-72cjogxz 3519 10 much much RB cord-015369-72cjogxz 3519 11 lower low JJR cord-015369-72cjogxz 3519 12 mortality mortality NN cord-015369-72cjogxz 3519 13 . . . cord-015369-72cjogxz 3520 1 We -PRON- PRP cord-015369-72cjogxz 3520 2 suggest suggest VBP cord-015369-72cjogxz 3520 3 that that IN cord-015369-72cjogxz 3520 4 selective selective JJ cord-015369-72cjogxz 3520 5 decontamination decontamination NN cord-015369-72cjogxz 3520 6 to to TO cord-015369-72cjogxz 3520 7 be be VB cord-015369-72cjogxz 3520 8 used use VBN cord-015369-72cjogxz 3520 9 routinely routinely RB cord-015369-72cjogxz 3520 10 in in IN cord-015369-72cjogxz 3520 11 patients patient NNS cord-015369-72cjogxz 3520 12 having have VBG cord-015369-72cjogxz 3520 13 an an DT cord-015369-72cjogxz 3520 14 esophageal esophageal JJ cord-015369-72cjogxz 3520 15 anastomosis anastomosis NN cord-015369-72cjogxz 3520 16 . . . cord-015369-72cjogxz 3521 1 Marienhospital Marienhospital NNP cord-015369-72cjogxz 3521 2 , , , cord-015369-72cjogxz 3521 3 Ruhr Ruhr NNP cord-015369-72cjogxz 3521 4 - - HYPH cord-015369-72cjogxz 3521 5 Universität Universität NNP cord-015369-72cjogxz 3521 6 Bochum Bochum NNP cord-015369-72cjogxz 3521 7 , , , cord-015369-72cjogxz 3521 8 Herne Herne NNP cord-015369-72cjogxz 3521 9 , , , cord-015369-72cjogxz 3521 10 Germany Germany NNP cord-015369-72cjogxz 3521 11 Die Die NNP cord-015369-72cjogxz 3521 12 Therapie Therapie NNP cord-015369-72cjogxz 3521 13 des des FW cord-015369-72cjogxz 3521 14 Ö Ö NNP cord-015369-72cjogxz 3521 15 sophaguskarzinoms sophaguskarzinom NNS cord-015369-72cjogxz 3522 1 ist ist NNP cord-015369-72cjogxz 3522 2 inzwischen inzwischen NNP cord-015369-72cjogxz 3522 3 zu zu NNP cord-015369-72cjogxz 3522 4 ca ca NNP cord-015369-72cjogxz 3522 5 . . . cord-015369-72cjogxz 3523 1 80 80 CD cord-015369-72cjogxz 3523 2 % % NN cord-015369-72cjogxz 3523 3 multimodal multimodal NN cord-015369-72cjogxz 3523 4 ausgerichtet ausgerichtet NNP cord-015369-72cjogxz 3523 5 . . . cord-015369-72cjogxz 3524 1 Jedoch Jedoch NNP cord-015369-72cjogxz 3524 2 ist ist FW cord-015369-72cjogxz 3524 3 immer immer NNP cord-015369-72cjogxz 3524 4 noch noch NNP cord-015369-72cjogxz 3524 5 unklar unklar NNP cord-015369-72cjogxz 3525 1 welche welche NNP cord-015369-72cjogxz 3525 2 Modalität Modalität NNP cord-015369-72cjogxz 3525 3 zur zur NNP cord-015369-72cjogxz 3525 4 welcher welcher NNP cord-015369-72cjogxz 3525 5 Zeit Zeit NNP cord-015369-72cjogxz 3525 6 und und NNP cord-015369-72cjogxz 3525 7 in in IN cord-015369-72cjogxz 3525 8 welcher welcher NNP cord-015369-72cjogxz 3525 9 Reihenfolge Reihenfolge NNP cord-015369-72cjogxz 3525 10 angewandt angewandt NNP cord-015369-72cjogxz 3525 11 werden werden NNP cord-015369-72cjogxz 3525 12 soll soll NNP cord-015369-72cjogxz 3525 13 . . . cord-015369-72cjogxz 3526 1 Beim Beim NNP cord-015369-72cjogxz 3526 2 lokal lokal NNP cord-015369-72cjogxz 3526 3 fortgeschrittenen fortgeschrittenen NNP cord-015369-72cjogxz 3527 1 Plattenephithelkarzinom Plattenephithelkarzinom NNP cord-015369-72cjogxz 3527 2 des des FW cord-015369-72cjogxz 3527 3 Ö Ö NNP cord-015369-72cjogxz 3527 4 sophagus sophagus FW cord-015369-72cjogxz 3527 5 wird wird NNP cord-015369-72cjogxz 3527 6 generell generell NNP cord-015369-72cjogxz 3527 7 die die VBP cord-015369-72cjogxz 3527 8 neoadjuvante neoadjuvante NNP cord-015369-72cjogxz 3527 9 Radio Radio NNP cord-015369-72cjogxz 3527 10 - - HYPH cord-015369-72cjogxz 3527 11 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 3527 12 als als NNP cord-015369-72cjogxz 3527 13 Standard Standard NNP cord-015369-72cjogxz 3527 14 angesehen angesehen NNP cord-015369-72cjogxz 3527 15 , , , cord-015369-72cjogxz 3527 16 teilweise teilweise RB cord-015369-72cjogxz 3527 17 wird wird NNP cord-015369-72cjogxz 3527 18 diese diese NNP cord-015369-72cjogxz 3527 19 nach nach NNP cord-015369-72cjogxz 3527 20 einer einer NNP cord-015369-72cjogxz 3527 21 so so RB cord-015369-72cjogxz 3527 22 - - HYPH cord-015369-72cjogxz 3527 23 genannten genannten JJ cord-015369-72cjogxz 3527 24 Induktionstherapie Induktionstherapie NNP cord-015369-72cjogxz 3527 25 durchgeführt durchgeführt NN cord-015369-72cjogxz 3527 26 . . . cord-015369-72cjogxz 3528 1 Dieses Dieses NNP cord-015369-72cjogxz 3528 2 Vorgehen Vorgehen NNP cord-015369-72cjogxz 3528 3 ist ist NN cord-015369-72cjogxz 3528 4 bis bis NN cord-015369-72cjogxz 3528 5 heute heute NN cord-015369-72cjogxz 3528 6 jedoch jedoch NNP cord-015369-72cjogxz 3528 7 in in IN cord-015369-72cjogxz 3528 8 keiner keiner NNP cord-015369-72cjogxz 3528 9 randomisierten randomisierten NNP cord-015369-72cjogxz 3528 10 abschließend abschließend NNP cord-015369-72cjogxz 3528 11 Studie Studie NNP cord-015369-72cjogxz 3528 12 bewiesen bewiesen NNP cord-015369-72cjogxz 3528 13 , , , cord-015369-72cjogxz 3528 14 auch auch NNP cord-015369-72cjogxz 3528 15 wenn wenn NNP cord-015369-72cjogxz 3529 1 eine eine NNP cord-015369-72cjogxz 3529 2 kürzlich kürzlich NNP cord-015369-72cjogxz 3529 3 publizierte publizierte NNS cord-015369-72cjogxz 3529 4 Meta Meta NNP cord-015369-72cjogxz 3529 5 - - HYPH cord-015369-72cjogxz 3529 6 Analyse Analyse NNP cord-015369-72cjogxz 3529 7 einen einen JJ cord-015369-72cjogxz 3529 8 marginalen marginalen NN cord-015369-72cjogxz 3529 9 Vorteil Vorteil NNP cord-015369-72cjogxz 3529 10 der der NNP cord-015369-72cjogxz 3529 11 multimodalen multimodalen NNP cord-015369-72cjogxz 3529 12 Therapie Therapie NNP cord-015369-72cjogxz 3529 13 beschreibt beschreibt NNP cord-015369-72cjogxz 3529 14 . . . cord-015369-72cjogxz 3530 1 Nach Nach NNP cord-015369-72cjogxz 3530 2 kürzlich kürzlich NN cord-015369-72cjogxz 3530 3 publizierten publizierten NN cord-015369-72cjogxz 3530 4 Daten Daten NNP cord-015369-72cjogxz 3531 1 ( ( -LRB- cord-015369-72cjogxz 3531 2 Bedenne Bedenne NNP cord-015369-72cjogxz 3531 3 et et NNP cord-015369-72cjogxz 3531 4 al al NNP cord-015369-72cjogxz 3531 5 . . NNP cord-015369-72cjogxz 3531 6 , , , cord-015369-72cjogxz 3531 7 ASCO ASCO NNP cord-015369-72cjogxz 3531 8 , , , cord-015369-72cjogxz 3531 9 2008 2008 CD cord-015369-72cjogxz 3532 1 , , , cord-015369-72cjogxz 3532 2 Stahl Stahl NNP cord-015369-72cjogxz 3532 3 et et NNP cord-015369-72cjogxz 3532 4 al al NNP cord-015369-72cjogxz 3532 5 . . . cord-015369-72cjogxz 3533 1 JCO JCO NNP cord-015369-72cjogxz 3533 2 2009 2009 CD cord-015369-72cjogxz 3533 3 ) ) -RRB- cord-015369-72cjogxz 3534 1 scheint scheint NNP cord-015369-72cjogxz 3534 2 der der NNP cord-015369-72cjogxz 3534 3 Vorteil Vorteil NNP cord-015369-72cjogxz 3534 4 der der NNP cord-015369-72cjogxz 3534 5 Resektion Resektion NNP cord-015369-72cjogxz 3534 6 sich sich NNP cord-015369-72cjogxz 3534 7 vor vor NNP cord-015369-72cjogxz 3535 1 allem allem NNP cord-015369-72cjogxz 3535 2 auf auf NNP cord-015369-72cjogxz 3535 3 die die VBP cord-015369-72cjogxz 3536 1 Patienten Patienten NNP cord-015369-72cjogxz 3536 2 zu zu NNP cord-015369-72cjogxz 3536 3 beschränken beschränken NNP cord-015369-72cjogxz 3536 4 , , , cord-015369-72cjogxz 3536 5 die die VBP cord-015369-72cjogxz 3536 6 auf auf NNP cord-015369-72cjogxz 3536 7 die die VB cord-015369-72cjogxz 3536 8 multimodale multimodale NN cord-015369-72cjogxz 3536 9 Therapie Therapie NNP cord-015369-72cjogxz 3536 10 nicht nicht NNP cord-015369-72cjogxz 3536 11 oder oder NNP cord-015369-72cjogxz 3536 12 nur nur NNP cord-015369-72cjogxz 3536 13 unzureichend unzureichend NNP cord-015369-72cjogxz 3536 14 ansprechen ansprechen NNP cord-015369-72cjogxz 3536 15 . . . cord-015369-72cjogxz 3537 1 Anders Anders NNP cord-015369-72cjogxz 3537 2 verhält verhält CC cord-015369-72cjogxz 3537 3 es es NNP cord-015369-72cjogxz 3537 4 sich sich NNP cord-015369-72cjogxz 3537 5 bei bei NNP cord-015369-72cjogxz 3537 6 den den NNP cord-015369-72cjogxz 3537 7 Adenokarzinomen Adenokarzinomen NNP cord-015369-72cjogxz 3537 8 des des FW cord-015369-72cjogxz 3537 9 distalen distalen FW cord-015369-72cjogxz 3537 10 Ö Ö NNP cord-015369-72cjogxz 3537 11 sophagus sophagus NNP cord-015369-72cjogxz 3537 12 . . . cord-015369-72cjogxz 3538 1 Nach Nach NNP cord-015369-72cjogxz 3538 2 drei drei NNS cord-015369-72cjogxz 3538 3 randomisierten randomisierten FW cord-015369-72cjogxz 3538 4 Studien Studien NNP cord-015369-72cjogxz 3538 5 , , , cord-015369-72cjogxz 3538 6 die die VB cord-015369-72cjogxz 3538 7 mehrheitlich mehrheitlich NNP cord-015369-72cjogxz 3538 8 Barrett Barrett NNP cord-015369-72cjogxz 3538 9 Karzinome Karzinome NNP cord-015369-72cjogxz 3538 10 einschlossen einschlossen NNP cord-015369-72cjogxz 3538 11 , , , cord-015369-72cjogxz 3538 12 ist ist NNP cord-015369-72cjogxz 3538 13 die die VBP cord-015369-72cjogxz 3538 14 neoadjuvante neoadjuvante JJ cord-015369-72cjogxz 3538 15 Chemotherapie chemotherapie NN cord-015369-72cjogxz 3538 16 bei bei NNP cord-015369-72cjogxz 3538 17 lokal lokal NNP cord-015369-72cjogxz 3538 18 fortgeschrittenen fortgeschrittenen NNP cord-015369-72cjogxz 3538 19 Adenokarzinomen Adenokarzinomen NNP cord-015369-72cjogxz 3538 20 als als NNP cord-015369-72cjogxz 3538 21 internationaler internationaler NNP cord-015369-72cjogxz 3538 22 Standard Standard NNP cord-015369-72cjogxz 3538 23 angesehen angesehen NNP cord-015369-72cjogxz 3538 24 . . . cord-015369-72cjogxz 3539 1 Neuere Neuere NNP cord-015369-72cjogxz 3539 2 Studien Studien NNP cord-015369-72cjogxz 3539 3 untersuchen untersuchen NN cord-015369-72cjogxz 3539 4 derzeit derzeit NNP cord-015369-72cjogxz 3539 5 den den NNP cord-015369-72cjogxz 3539 6 Einfluss Einfluss NNP cord-015369-72cjogxz 3539 7 der der NN cord-015369-72cjogxz 3539 8 präoperativen präoperativen NNP cord-015369-72cjogxz 3539 9 Radio Radio NNP cord-015369-72cjogxz 3539 10 - - HYPH cord-015369-72cjogxz 3539 11 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 3539 12 auch auch NNP cord-015369-72cjogxz 3539 13 bei bei NNP cord-015369-72cjogxz 3539 14 Adenokarzinomen Adenokarzinomen NNP cord-015369-72cjogxz 3539 15 des des FW cord-015369-72cjogxz 3539 16 distalen distalen FW cord-015369-72cjogxz 3539 17 Ö Ö NNP cord-015369-72cjogxz 3539 18 sophagus sophagus NNP cord-015369-72cjogxz 3539 19 sowohl sowohl NNP cord-015369-72cjogxz 3539 20 auf auf NNP cord-015369-72cjogxz 3539 21 das das NNP cord-015369-72cjogxz 3539 22 Rezidiv Rezidiv NNP cord-015369-72cjogxz 3539 23 - - HYPH cord-015369-72cjogxz 3539 24 freie freie NNP cord-015369-72cjogxz 3539 25 als als NNP cord-015369-72cjogxz 3539 26 auch auch NNP cord-015369-72cjogxz 3539 27 auf auf NNP cord-015369-72cjogxz 3539 28 das das NNP cord-015369-72cjogxz 3539 29 Langzeitüberleben Langzeitüberleben NNP cord-015369-72cjogxz 3539 30 nach nach NNP cord-015369-72cjogxz 3539 31 Resektion Resektion NNP cord-015369-72cjogxz 3539 32 . . . cord-015369-72cjogxz 3540 1 Nach Nach NNP cord-015369-72cjogxz 3540 2 ersten ersten NNP cord-015369-72cjogxz 3540 3 Daten Daten NNP cord-015369-72cjogxz 3540 4 schient schient NN cord-015369-72cjogxz 3540 5 die die VB cord-015369-72cjogxz 3541 1 Resektion Resektion NNP cord-015369-72cjogxz 3541 2 nicht nicht NNP cord-015369-72cjogxz 3541 3 mit mit NNP cord-015369-72cjogxz 3541 4 einer einer NNP cord-015369-72cjogxz 3541 5 erhöhten erhöhten NNP cord-015369-72cjogxz 3542 1 Morbidität Morbidität NNP cord-015369-72cjogxz 3542 2 oder oder NNP cord-015369-72cjogxz 3542 3 Letalität Letalität NNP cord-015369-72cjogxz 3542 4 einherzugehen einherzugehen NN cord-015369-72cjogxz 3542 5 . . . cord-015369-72cjogxz 3543 1 I -PRON- PRP cord-015369-72cjogxz 3544 1 m m NNP cord-015369-72cjogxz 3544 2 Vortrag Vortrag NNP cord-015369-72cjogxz 3544 3 werden werden NNP cord-015369-72cjogxz 3544 4 die die VBP cord-015369-72cjogxz 3544 5 aktuellen aktuellen JJ cord-015369-72cjogxz 3544 6 Studien Studien NNP cord-015369-72cjogxz 3544 7 und und NNP cord-015369-72cjogxz 3544 8 der der NNP cord-015369-72cjogxz 3544 9 derzeitige derzeitige NNP cord-015369-72cjogxz 3544 10 Therapiestandard Therapiestandard NNP cord-015369-72cjogxz 3544 11 der der NN cord-015369-72cjogxz 3544 12 multimodalen multimodalen NNP cord-015369-72cjogxz 3544 13 Therapie Therapie NNP cord-015369-72cjogxz 3544 14 bei bei NNP cord-015369-72cjogxz 3544 15 Karzinomen Karzinomen NNP cord-015369-72cjogxz 3544 16 des des FW cord-015369-72cjogxz 3544 17 Ö Ö NNP cord-015369-72cjogxz 3544 18 sophagus sophagus FW cord-015369-72cjogxz 3544 19 dargestellt dargestellt NNP cord-015369-72cjogxz 3544 20 . . . cord-015369-72cjogxz 3545 1 Prognose Prognose NNP cord-015369-72cjogxz 3545 2 bedeutend bedeutend NNP cord-015369-72cjogxz 3545 3 verbessert verbessert NNP cord-015369-72cjogxz 3545 4 und und NNP cord-015369-72cjogxz 3545 5 in in IN cord-015369-72cjogxz 3545 6 zunehmender zunehmender XX cord-015369-72cjogxz 3546 1 Häufigkeit Häufigkeit NNP cord-015369-72cjogxz 3546 2 ist ist NN cord-015369-72cjogxz 3546 3 auch auch NNP cord-015369-72cjogxz 3546 4 eine eine JJ cord-015369-72cjogxz 3546 5 kurative kurative NNP cord-015369-72cjogxz 3546 6 Therapie Therapie NNP cord-015369-72cjogxz 3546 7 möglich möglich NNP cord-015369-72cjogxz 3546 8 . . . cord-015369-72cjogxz 3547 1 Besondere Besondere NNP cord-015369-72cjogxz 3547 2 Fortschritte Fortschritte NNP cord-015369-72cjogxz 3547 3 gab gab NN cord-015369-72cjogxz 3547 4 es es XX cord-015369-72cjogxz 3547 5 in in IN cord-015369-72cjogxz 3547 6 der der NNP cord-015369-72cjogxz 3547 7 medizinisch medizinisch NNP cord-015369-72cjogxz 3547 8 onkologischen onkologischen NNP cord-015369-72cjogxz 3547 9 Therapie Therapie NNP cord-015369-72cjogxz 3548 1 , , , cord-015369-72cjogxz 3548 2 wodurch wodurch NNP cord-015369-72cjogxz 3549 1 mittlerweile mittlerweile NNP cord-015369-72cjogxz 3549 2 mediane mediane NNP cord-015369-72cjogxz 3549 3 Ü Ü NNP cord-015369-72cjogxz 3550 1 berlebensraten berlebensraten NNP cord-015369-72cjogxz 3551 1 von von NNP cord-015369-72cjogxz 3551 2 über über NNP cord-015369-72cjogxz 3552 1 2 2 CD cord-015369-72cjogxz 3552 2 Jahren Jahren NNP cord-015369-72cjogxz 3552 3 erreicht erreicht NN cord-015369-72cjogxz 3552 4 werden werden NNP cord-015369-72cjogxz 3552 5 können können NNP cord-015369-72cjogxz 3552 6 . . . cord-015369-72cjogxz 3553 1 Die die VB cord-015369-72cjogxz 3553 2 chirurgische chirurgische NNP cord-015369-72cjogxz 3553 3 Therapie Therapie NNP cord-015369-72cjogxz 3553 4 ist ist NNP cord-015369-72cjogxz 3553 5 bedeutend bedeutend NNP cord-015369-72cjogxz 3553 6 sicherer sicherer NNP cord-015369-72cjogxz 3553 7 geworden geworden NNP cord-015369-72cjogxz 3553 8 , , , cord-015369-72cjogxz 3553 9 erlaubt erlaubt NNP cord-015369-72cjogxz 3553 10 große große NNP cord-015369-72cjogxz 3553 11 Resektionen Resektionen NNP cord-015369-72cjogxz 3553 12 auch auch NNP cord-015369-72cjogxz 3553 13 bei bei NNP cord-015369-72cjogxz 3553 14 chemotherapeutisch chemotherapeutisch NNP cord-015369-72cjogxz 3554 1 vorbehandelten vorbehandelten NNP cord-015369-72cjogxz 3555 1 Patienten Patienten NNP cord-015369-72cjogxz 3555 2 mit mit VBP cord-015369-72cjogxz 3555 3 geringer geringer NN cord-015369-72cjogxz 3555 4 Morbidität Morbidität NNP cord-015369-72cjogxz 3555 5 und und XX cord-015369-72cjogxz 3556 1 schließlich schließlich NNP cord-015369-72cjogxz 3556 2 wurde wurde NNP cord-015369-72cjogxz 3556 3 das das NNP cord-015369-72cjogxz 3556 4 therapeutische therapeutische NNP cord-015369-72cjogxz 3556 5 Armamentarium Armamentarium NNP cord-015369-72cjogxz 3556 6 durch durch NNP cord-015369-72cjogxz 3556 7 interventionelle interventionelle NNP cord-015369-72cjogxz 3556 8 radiologische radiologische NN cord-015369-72cjogxz 3556 9 , , , cord-015369-72cjogxz 3556 10 nuklearmedizinische nuklearmedizinische NNP cord-015369-72cjogxz 3556 11 und und NNP cord-015369-72cjogxz 3556 12 strahlentherapeutische strahlentherapeutische NNP cord-015369-72cjogxz 3556 13 Möglichkeiten Möglichkeiten NNP cord-015369-72cjogxz 3556 14 erweitert erweitert NNP cord-015369-72cjogxz 3556 15 . . . cord-015369-72cjogxz 3557 1 Deshalb Deshalb NNP cord-015369-72cjogxz 3557 2 Background Background NNP cord-015369-72cjogxz 3557 3 . . . cord-015369-72cjogxz 3558 1 Lipocalin-2 Lipocalin-2 NNP cord-015369-72cjogxz 3559 1 ( ( -LRB- cord-015369-72cjogxz 3559 2 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3559 3 , , , cord-015369-72cjogxz 3559 4 NGAL NGAL NNP cord-015369-72cjogxz 3559 5 ) ) -RRB- cord-015369-72cjogxz 3559 6 was be VBD cord-015369-72cjogxz 3559 7 recently recently RB cord-015369-72cjogxz 3559 8 shown show VBN cord-015369-72cjogxz 3559 9 to to TO cord-015369-72cjogxz 3559 10 be be VB cord-015369-72cjogxz 3559 11 highly highly RB cord-015369-72cjogxz 3559 12 expressed express VBN cord-015369-72cjogxz 3559 13 in in IN cord-015369-72cjogxz 3559 14 various various JJ cord-015369-72cjogxz 3559 15 human human JJ cord-015369-72cjogxz 3559 16 cancers cancer NNS cord-015369-72cjogxz 3559 17 and and CC cord-015369-72cjogxz 3559 18 increased increase VBN cord-015369-72cjogxz 3559 19 protein protein NN cord-015369-72cjogxz 3559 20 levels level NNS cord-015369-72cjogxz 3559 21 were be VBD cord-015369-72cjogxz 3559 22 associated associate VBN cord-015369-72cjogxz 3559 23 with with IN cord-015369-72cjogxz 3559 24 worse bad JJR cord-015369-72cjogxz 3559 25 survival survival NN cord-015369-72cjogxz 3559 26 of of IN cord-015369-72cjogxz 3559 27 patients patient NNS cord-015369-72cjogxz 3559 28 with with IN cord-015369-72cjogxz 3559 29 breast breast NN cord-015369-72cjogxz 3559 30 , , , cord-015369-72cjogxz 3559 31 gastric gastric JJ cord-015369-72cjogxz 3559 32 or or CC cord-015369-72cjogxz 3559 33 oesophageal oesophageal JJ cord-015369-72cjogxz 3559 34 cancer cancer NN cord-015369-72cjogxz 3559 35 . . . cord-015369-72cjogxz 3560 1 The the DT cord-015369-72cjogxz 3560 2 main main JJ cord-015369-72cjogxz 3560 3 focus focus NN cord-015369-72cjogxz 3560 4 of of IN cord-015369-72cjogxz 3560 5 this this DT cord-015369-72cjogxz 3560 6 work work NN cord-015369-72cjogxz 3560 7 was be VBD cord-015369-72cjogxz 3560 8 to to TO cord-015369-72cjogxz 3560 9 analyze analyze VB cord-015369-72cjogxz 3560 10 the the DT cord-015369-72cjogxz 3560 11 possible possible JJ cord-015369-72cjogxz 3560 12 implication implication NN cord-015369-72cjogxz 3560 13 of of IN cord-015369-72cjogxz 3560 14 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3560 15 upregulation upregulation NN cord-015369-72cjogxz 3560 16 in in IN cord-015369-72cjogxz 3560 17 colon colon NN cord-015369-72cjogxz 3560 18 cancer cancer NN cord-015369-72cjogxz 3560 19 development development NN cord-015369-72cjogxz 3560 20 . . . cord-015369-72cjogxz 3561 1 Methods method NNS cord-015369-72cjogxz 3561 2 . . . cord-015369-72cjogxz 3562 1 Expression expression NN cord-015369-72cjogxz 3562 2 of of IN cord-015369-72cjogxz 3562 3 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3562 4 was be VBD cord-015369-72cjogxz 3562 5 analyzed analyze VBN cord-015369-72cjogxz 3562 6 in in IN cord-015369-72cjogxz 3562 7 various various JJ cord-015369-72cjogxz 3562 8 colorectal colorectal JJ cord-015369-72cjogxz 3562 9 carcinoma carcinoma NN cord-015369-72cjogxz 3562 10 cell cell NN cord-015369-72cjogxz 3562 11 lines line NNS cord-015369-72cjogxz 3562 12 , , , cord-015369-72cjogxz 3562 13 paired pair VBD cord-015369-72cjogxz 3562 14 colorectal colorectal JJ cord-015369-72cjogxz 3562 15 carcinoma carcinoma NN cord-015369-72cjogxz 3562 16 tissues tissue NNS cord-015369-72cjogxz 3562 17 and and CC cord-015369-72cjogxz 3562 18 normal normal JJ cord-015369-72cjogxz 3562 19 mucosas mucosas NN cord-015369-72cjogxz 3562 20 by by IN cord-015369-72cjogxz 3562 21 Western western JJ cord-015369-72cjogxz 3562 22 blot blot NN cord-015369-72cjogxz 3562 23 . . . cord-015369-72cjogxz 3563 1 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3563 2 immunostaining immunostaine VBG cord-015369-72cjogxz 3563 3 was be VBD cord-015369-72cjogxz 3563 4 performed perform VBN cord-015369-72cjogxz 3563 5 in in IN cord-015369-72cjogxz 3563 6 213 213 CD cord-015369-72cjogxz 3563 7 colorectal colorectal JJ cord-015369-72cjogxz 3563 8 carcinoma carcinoma NN cord-015369-72cjogxz 3563 9 resection resection NN cord-015369-72cjogxz 3563 10 specimens specimen NNS cord-015369-72cjogxz 3563 11 ( ( -LRB- cord-015369-72cjogxz 3563 12 Intensity intensity NN cord-015369-72cjogxz 3563 13 score score NN cord-015369-72cjogxz 3563 14 0 0 CD cord-015369-72cjogxz 3563 15 - - SYM cord-015369-72cjogxz 3563 16 3 3 CD cord-015369-72cjogxz 3563 17 ) ) -RRB- cord-015369-72cjogxz 3563 18 and and CC cord-015369-72cjogxz 3563 19 correlated correlate VBN cord-015369-72cjogxz 3563 20 with with IN cord-015369-72cjogxz 3563 21 clinical clinical JJ cord-015369-72cjogxz 3563 22 parameters parameter NNS cord-015369-72cjogxz 3563 23 . . . cord-015369-72cjogxz 3564 1 Colorectal colorectal JJ cord-015369-72cjogxz 3564 2 carcinoma carcinoma NN cord-015369-72cjogxz 3564 3 cell cell NN cord-015369-72cjogxz 3564 4 lines line NNS cord-015369-72cjogxz 3564 5 were be VBD cord-015369-72cjogxz 3564 6 treated treat VBN cord-015369-72cjogxz 3564 7 with with IN cord-015369-72cjogxz 3564 8 various various JJ cord-015369-72cjogxz 3564 9 concentrations concentration NNS cord-015369-72cjogxz 3564 10 of of IN cord-015369-72cjogxz 3564 11 recombinant recombinant JJ cord-015369-72cjogxz 3564 12 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3564 13 protein protein NN cord-015369-72cjogxz 3564 14 and and CC cord-015369-72cjogxz 3564 15 monitored monitor VBN cord-015369-72cjogxz 3564 16 for for IN cord-015369-72cjogxz 3564 17 growth growth NN cord-015369-72cjogxz 3564 18 and and CC cord-015369-72cjogxz 3564 19 survival survival NN cord-015369-72cjogxz 3564 20 . . . cord-015369-72cjogxz 3565 1 Results result NNS cord-015369-72cjogxz 3565 2 . . . cord-015369-72cjogxz 3566 1 Western western JJ cord-015369-72cjogxz 3566 2 blot blot NN cord-015369-72cjogxz 3566 3 analysis analysis NN cord-015369-72cjogxz 3566 4 of of IN cord-015369-72cjogxz 3566 5 colorectal colorectal JJ cord-015369-72cjogxz 3566 6 carcinoma carcinoma NN cord-015369-72cjogxz 3566 7 cell cell NN cord-015369-72cjogxz 3566 8 lines line NNS cord-015369-72cjogxz 3566 9 and and CC cord-015369-72cjogxz 3566 10 tissues tissue NNS cord-015369-72cjogxz 3566 11 clearly clearly RB cord-015369-72cjogxz 3566 12 demonstrated demonstrate VBD cord-015369-72cjogxz 3566 13 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3566 14 overexpression overexpression NN cord-015369-72cjogxz 3566 15 in in IN cord-015369-72cjogxz 3566 16 carcinomas carcinoma NNS cord-015369-72cjogxz 3566 17 compared compare VBN cord-015369-72cjogxz 3566 18 with with IN cord-015369-72cjogxz 3566 19 normal normal JJ cord-015369-72cjogxz 3566 20 mucosas mucosas NN cord-015369-72cjogxz 3566 21 in in IN cord-015369-72cjogxz 3566 22 all all DT cord-015369-72cjogxz 3566 23 colorectal colorectal JJ cord-015369-72cjogxz 3566 24 carcinoma carcinoma NN cord-015369-72cjogxz 3566 25 tissue tissue NN cord-015369-72cjogxz 3566 26 pairs pair NNS cord-015369-72cjogxz 3566 27 analysed analyse VBD cord-015369-72cjogxz 3566 28 . . . cord-015369-72cjogxz 3567 1 Immunostaining immunostaining NN cord-015369-72cjogxz 3567 2 revealed reveal VBD cord-015369-72cjogxz 3567 3 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3567 4 overexpression overexpression NN cord-015369-72cjogxz 3567 5 in in IN cord-015369-72cjogxz 3567 6 199 199 CD cord-015369-72cjogxz 3567 7 ( ( -LRB- cord-015369-72cjogxz 3567 8 93.4 93.4 CD cord-015369-72cjogxz 3567 9 % % NN cord-015369-72cjogxz 3567 10 ) ) -RRB- cord-015369-72cjogxz 3567 11 of of IN cord-015369-72cjogxz 3567 12 colorectal colorectal JJ cord-015369-72cjogxz 3567 13 carcinoma carcinoma NN cord-015369-72cjogxz 3567 14 tissues tissue NNS cord-015369-72cjogxz 3567 15 . . . cord-015369-72cjogxz 3568 1 Intense intense JJ cord-015369-72cjogxz 3568 2 immunoreactivity immunoreactivity NN cord-015369-72cjogxz 3568 3 was be VBD cord-015369-72cjogxz 3568 4 significantly significantly RB cord-015369-72cjogxz 3568 5 correlated correlate VBN cord-015369-72cjogxz 3568 6 with with IN cord-015369-72cjogxz 3568 7 tumor tumor NN cord-015369-72cjogxz 3568 8 grading grading NN cord-015369-72cjogxz 3568 9 ( ( -LRB- cord-015369-72cjogxz 3568 10 p p NN cord-015369-72cjogxz 3568 11 < < XX cord-015369-72cjogxz 3568 12 0.041 0.041 XX cord-015369-72cjogxz 3568 13 ) ) -RRB- cord-015369-72cjogxz 3568 14 . . . cord-015369-72cjogxz 3569 1 Cancer cancer NN cord-015369-72cjogxz 3569 2 samples sample NNS cord-015369-72cjogxz 3569 3 of of IN cord-015369-72cjogxz 3569 4 the the DT cord-015369-72cjogxz 3569 5 right right JJ cord-015369-72cjogxz 3569 6 hemicolon hemicolon NNP cord-015369-72cjogxz 3569 7 showed show VBD cord-015369-72cjogxz 3569 8 significantly significantly RB cord-015369-72cjogxz 3569 9 higher high JJR cord-015369-72cjogxz 3569 10 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3569 11 expression expression NN cord-015369-72cjogxz 3569 12 decreasing decrease VBG cord-015369-72cjogxz 3569 13 in in IN cord-015369-72cjogxz 3569 14 the the DT cord-015369-72cjogxz 3569 15 left left JJ cord-015369-72cjogxz 3569 16 hemicolon hemicolon NN cord-015369-72cjogxz 3569 17 and and CC cord-015369-72cjogxz 3569 18 the the DT cord-015369-72cjogxz 3569 19 rectum rectum NN cord-015369-72cjogxz 3569 20 ( ( -LRB- cord-015369-72cjogxz 3569 21 p p NN cord-015369-72cjogxz 3569 22 < < XX cord-015369-72cjogxz 3569 23 0.001 0.001 CD cord-015369-72cjogxz 3569 24 ) ) -RRB- cord-015369-72cjogxz 3569 25 . . . cord-015369-72cjogxz 3570 1 Addition addition NN cord-015369-72cjogxz 3570 2 of of IN cord-015369-72cjogxz 3570 3 various various JJ cord-015369-72cjogxz 3570 4 concentrations concentration NNS cord-015369-72cjogxz 3570 5 of of IN cord-015369-72cjogxz 3570 6 recombinant recombinant JJ cord-015369-72cjogxz 3570 7 human human NN cord-015369-72cjogxz 3570 8 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3570 9 protein protein NN cord-015369-72cjogxz 3570 10 to to IN cord-015369-72cjogxz 3570 11 colorectal colorectal JJ cord-015369-72cjogxz 3570 12 carcinoma carcinoma NN cord-015369-72cjogxz 3570 13 cell cell NN cord-015369-72cjogxz 3570 14 lines line NNS cord-015369-72cjogxz 3570 15 did do VBD cord-015369-72cjogxz 3570 16 not not RB cord-015369-72cjogxz 3570 17 have have VB cord-015369-72cjogxz 3570 18 any any DT cord-015369-72cjogxz 3570 19 influence influence NN cord-015369-72cjogxz 3570 20 on on IN cord-015369-72cjogxz 3570 21 cell cell NN cord-015369-72cjogxz 3570 22 growth growth NN cord-015369-72cjogxz 3570 23 and and CC cord-015369-72cjogxz 3570 24 survival survival NN cord-015369-72cjogxz 3570 25 in in IN cord-015369-72cjogxz 3570 26 vitro vitro FW cord-015369-72cjogxz 3570 27 . . . cord-015369-72cjogxz 3571 1 Conclusions conclusion NNS cord-015369-72cjogxz 3571 2 . . . cord-015369-72cjogxz 3572 1 Our -PRON- PRP$ cord-015369-72cjogxz 3572 2 data datum NNS cord-015369-72cjogxz 3572 3 provide provide VBP cord-015369-72cjogxz 3572 4 evidence evidence NN cord-015369-72cjogxz 3572 5 that that IN cord-015369-72cjogxz 3572 6 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3572 7 expression expression NN cord-015369-72cjogxz 3572 8 is be VBZ cord-015369-72cjogxz 3572 9 upregulated upregulate VBN cord-015369-72cjogxz 3572 10 with with IN cord-015369-72cjogxz 3572 11 tumor tumor NN cord-015369-72cjogxz 3572 12 progression progression NN cord-015369-72cjogxz 3572 13 . . . cord-015369-72cjogxz 3573 1 The the DT cord-015369-72cjogxz 3573 2 correlation correlation NN cord-015369-72cjogxz 3573 3 of of IN cord-015369-72cjogxz 3573 4 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3573 5 expression expression NN cord-015369-72cjogxz 3573 6 with with IN cord-015369-72cjogxz 3573 7 localisation localisation NN cord-015369-72cjogxz 3573 8 in in IN cord-015369-72cjogxz 3573 9 the the DT cord-015369-72cjogxz 3573 10 colon colon NN cord-015369-72cjogxz 3573 11 gives give VBZ cord-015369-72cjogxz 3573 12 molecular molecular JJ cord-015369-72cjogxz 3573 13 biological biological JJ cord-015369-72cjogxz 3573 14 evidence evidence NN cord-015369-72cjogxz 3573 15 for for IN cord-015369-72cjogxz 3573 16 distinguishing distinguish VBG cord-015369-72cjogxz 3573 17 subsites subsite NNS cord-015369-72cjogxz 3573 18 of of IN cord-015369-72cjogxz 3573 19 colorectal colorectal JJ cord-015369-72cjogxz 3573 20 cancer cancer NN cord-015369-72cjogxz 3573 21 . . . cord-015369-72cjogxz 3574 1 Targeting target VBG cord-015369-72cjogxz 3574 2 Lcn-2 Lcn-2 NNP cord-015369-72cjogxz 3574 3 might may MD cord-015369-72cjogxz 3574 4 be be VB cord-015369-72cjogxz 3574 5 a a DT cord-015369-72cjogxz 3574 6 new new JJ cord-015369-72cjogxz 3574 7 therapeutic therapeutic JJ cord-015369-72cjogxz 3574 8 strategy strategy NN cord-015369-72cjogxz 3574 9 in in IN cord-015369-72cjogxz 3574 10 colorectal colorectal JJ cord-015369-72cjogxz 3574 11 carcinoma carcinoma NN cord-015369-72cjogxz 3574 12 . . . cord-015369-72cjogxz 3575 1 Qualitätskontrolle Qualitätskontrolle NNP cord-015369-72cjogxz 3575 2 der der VBP cord-015369-72cjogxz 3575 3 primären primären NNP cord-015369-72cjogxz 3575 4 Rektumkarzinom Rektumkarzinom NNP cord-015369-72cjogxz 3575 5 -Chirurgie -Chirurgie NNP cord-015369-72cjogxz 3575 6 in in IN cord-015369-72cjogxz 3575 7 einem einem NNP cord-015369-72cjogxz 3575 8 nicht nicht NNP cord-015369-72cjogxz 3575 9 selektionierten selektionierten NNP cord-015369-72cjogxz 3575 10 , , , cord-015369-72cjogxz 3575 11 konsekutiven konsekutiven NNP cord-015369-72cjogxz 3575 12 Patientengut Patientengut NNP cord-015369-72cjogxz 3575 13 An an DT cord-015369-72cjogxz 3575 14 unserer unserer JJ cord-015369-72cjogxz 3575 15 Klinik Klinik NNP cord-015369-72cjogxz 3575 16 wurden wurden NNP cord-015369-72cjogxz 3575 17 in in IN cord-015369-72cjogxz 3575 18 zehn zehn NNP cord-015369-72cjogxz 3575 19 Jahren Jahren NNP cord-015369-72cjogxz 3575 20 153 153 CD cord-015369-72cjogxz 3575 21 Patienten Patienten NNP cord-015369-72cjogxz 3575 22 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 3575 23 radiochemotherapiert radiochemotherapiert NN cord-015369-72cjogxz 3575 24 ( ( -LRB- cord-015369-72cjogxz 3575 25 5 5 CD cord-015369-72cjogxz 3575 26 Wochen Wochen NNP cord-015369-72cjogxz 3575 27 ) ) -RRB- cord-015369-72cjogxz 3576 1 und und NNP cord-015369-72cjogxz 3576 2 anschließend anschließend NNP cord-015369-72cjogxz 3576 3 mittles mittles NNP cord-015369-72cjogxz 3577 1 TME TME NNP cord-015369-72cjogxz 3577 2 radikal radikal NNP cord-015369-72cjogxz 3577 3 operiert operiert NNP cord-015369-72cjogxz 3577 4 . . . cord-015369-72cjogxz 3578 1 Die die VB cord-015369-72cjogxz 3578 2 10-J 10-j CD cord-015369-72cjogxz 3578 3 - - HYPH cord-015369-72cjogxz 3578 4 Ü ü NN cord-015369-72cjogxz 3578 5 R R NNP cord-015369-72cjogxz 3578 6 betrug betrug NNP cord-015369-72cjogxz 3578 7 60 60 CD cord-015369-72cjogxz 3578 8 % % NN cord-015369-72cjogxz 3578 9 . . . cord-015369-72cjogxz 3579 1 Von Von NNP cord-015369-72cjogxz 3579 2 10 10 CD cord-015369-72cjogxz 3579 3 synchron synchron NNP cord-015369-72cjogxz 3579 4 metastasierten metastasierten NNP cord-015369-72cjogxz 3579 5 Patienten Patienten NNP cord-015369-72cjogxz 3579 6 , , , cord-015369-72cjogxz 3579 7 welche welche NNP cord-015369-72cjogxz 3579 8 nach nach NNP cord-015369-72cjogxz 3579 9 Therapie Therapie NNP cord-015369-72cjogxz 3579 10 des des NNP cord-015369-72cjogxz 3579 11 Primums Primums NNP cord-015369-72cjogxz 3579 12 metastasektomiert metastasektomiert NNP cord-015369-72cjogxz 3579 13 wurden wurden NNP cord-015369-72cjogxz 3579 14 , , , cord-015369-72cjogxz 3579 15 entwickelten entwickelten NNP cord-015369-72cjogxz 3579 16 80 80 CD cord-015369-72cjogxz 3579 17 % % NN cord-015369-72cjogxz 3579 18 ein ein NNP cord-015369-72cjogxz 3579 19 Tumorrezidiv Tumorrezidiv NNP cord-015369-72cjogxz 3579 20 , , , cord-015369-72cjogxz 3580 1 allerdings allerdings NNP cord-015369-72cjogxz 3580 2 wesentlich wesentlich NNP cord-015369-72cjogxz 3580 3 früher früher NNP cord-015369-72cjogxz 3580 4 als als NNP cord-015369-72cjogxz 3580 5 die die VBP cord-015369-72cjogxz 3580 6 primär primär NN cord-015369-72cjogxz 3580 7 nichtmetastasierten nichtmetastasierten NNP cord-015369-72cjogxz 3580 8 Patienten Patienten NNP cord-015369-72cjogxz 3580 9 . . . cord-015369-72cjogxz 3581 1 Die die VB cord-015369-72cjogxz 3582 1 Hälfte Hälfte NNP cord-015369-72cjogxz 3582 2 der der NNP cord-015369-72cjogxz 3582 3 synchron synchron NNP cord-015369-72cjogxz 3582 4 metastasierten metastasierten NNP cord-015369-72cjogxz 3583 1 Patienten Patienten NNP cord-015369-72cjogxz 3583 2 mit mit NNP cord-015369-72cjogxz 3584 1 Tumorrezidiv Tumorrezidiv NNP cord-015369-72cjogxz 3584 2 konnten konnten NNP cord-015369-72cjogxz 3585 1 kurativ kurativ NNP cord-015369-72cjogxz 3585 2 re re NNP cord-015369-72cjogxz 3585 3 - - NN cord-015369-72cjogxz 3585 4 operiert operiert NNP cord-015369-72cjogxz 3585 5 werden werden NNP cord-015369-72cjogxz 3585 6 , , , cord-015369-72cjogxz 3585 7 nur nur NNP cord-015369-72cjogxz 3585 8 ein ein NNP cord-015369-72cjogxz 3585 9 Patient Patient NNP cord-015369-72cjogxz 3585 10 blieb blieb NNP cord-015369-72cjogxz 3585 11 tumorfrei tumorfrei NN cord-015369-72cjogxz 3585 12 . . . cord-015369-72cjogxz 3586 1 Aufgrund Aufgrund NNP cord-015369-72cjogxz 3586 2 der der NN cord-015369-72cjogxz 3586 3 schlechten schlechten NNP cord-015369-72cjogxz 3586 4 Prognose Prognose NNP cord-015369-72cjogxz 3586 5 wird wird NNP cord-015369-72cjogxz 3586 6 in in IN cord-015369-72cjogxz 3586 7 den den NNP cord-015369-72cjogxz 3586 8 letzten letzten NNP cord-015369-72cjogxz 3586 9 Jahren Jahren NNP cord-015369-72cjogxz 3587 1 -analog -analog : cord-015369-72cjogxz 3587 2 zum zum NNP cord-015369-72cjogxz 3587 3 Kolonkarzinom Kolonkarzinom NNP cord-015369-72cjogxz 3587 4 -beim -beim HYPH cord-015369-72cjogxz 3587 5 synchron synchron NNP cord-015369-72cjogxz 3587 6 metastasierten metastasierten NNP cord-015369-72cjogxz 3587 7 Rektumkarzinom Rektumkarzinom NNP cord-015369-72cjogxz 3587 8 zunehmend zunehmend NNP cord-015369-72cjogxz 3588 1 eine eine NNP cord-015369-72cjogxz 3588 2 Ä Ä NNP cord-015369-72cjogxz 3588 3 nderung nderung NNP cord-015369-72cjogxz 3588 4 der der NNP cord-015369-72cjogxz 3588 5 Behandlungsstrategie Behandlungsstrategie NNP cord-015369-72cjogxz 3588 6 diskutiert diskutiert NNP cord-015369-72cjogxz 3588 7 . . . cord-015369-72cjogxz 3589 1 Die die VB cord-015369-72cjogxz 3589 2 Vorstellung Vorstellung NNP cord-015369-72cjogxz 3589 3 , , , cord-015369-72cjogxz 3589 4 dass dass NNP cord-015369-72cjogxz 3589 5 eine eine NNP cord-015369-72cjogxz 3589 6 systemische systemische NNP cord-015369-72cjogxz 3589 7 Erkrankung Erkrankung NNP cord-015369-72cjogxz 3590 1 eine eine NNP cord-015369-72cjogxz 3590 2 systemische systemische NNP cord-015369-72cjogxz 3590 3 Behandlung Behandlung NNP cord-015369-72cjogxz 3590 4 benötigt benötigt NNP cord-015369-72cjogxz 3590 5 , , , cord-015369-72cjogxz 3590 6 wird wird NNP cord-015369-72cjogxz 3590 7 dadurch dadurch NNP cord-015369-72cjogxz 3590 8 bekräftigt bekräftigt NNP cord-015369-72cjogxz 3590 9 , , , cord-015369-72cjogxz 3591 1 dass dass NNP cord-015369-72cjogxz 3591 2 eine eine NNP cord-015369-72cjogxz 3591 3 sekundäre sekundäre NNP cord-015369-72cjogxz 3591 4 Resektabilität Resektabilität NNP cord-015369-72cjogxz 3591 5 von von NNP cord-015369-72cjogxz 3592 1 marginal marginal NNP cord-015369-72cjogxz 3592 2 operablen operablen NNP cord-015369-72cjogxz 3592 3 / / SYM cord-015369-72cjogxz 3592 4 inoperablen inoperablen NNP cord-015369-72cjogxz 3592 5 Lebermetastasen Lebermetastasen NNP cord-015369-72cjogxz 3592 6 in in IN cord-015369-72cjogxz 3592 7 bis bis NNP cord-015369-72cjogxz 3592 8 zu zu XX cord-015369-72cjogxz 3593 1 40 40 CD cord-015369-72cjogxz 3593 2 % % NN cord-015369-72cjogxz 3593 3 gegeben gegeben NN cord-015369-72cjogxz 3593 4 ist ist NN cord-015369-72cjogxz 3593 5 und und IN cord-015369-72cjogxz 3593 6 auch auch NNP cord-015369-72cjogxz 3593 7 Patienten Patienten NNP cord-015369-72cjogxz 3593 8 mit mit NNP cord-015369-72cjogxz 3593 9 operablen operablen VBN cord-015369-72cjogxz 3593 10 Metastasen Metastasen NNP cord-015369-72cjogxz 3594 1 durch durch NNP cord-015369-72cjogxz 3594 2 die die VBP cord-015369-72cjogxz 3594 3 neoadjuvante neoadjuvante NNP cord-015369-72cjogxz 3594 4 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 3594 5 einen einen NNP cord-015369-72cjogxz 3594 6 Ü Ü NNP cord-015369-72cjogxz 3594 7 berlebensvorteil berlebensvorteil NNP cord-015369-72cjogxz 3594 8 aufweisen aufweisen NNP cord-015369-72cjogxz 3594 9 . . . cord-015369-72cjogxz 3595 1 Zudem Zudem NNP cord-015369-72cjogxz 3595 2 haben haben NNP cord-015369-72cjogxz 3595 3 wir wir NNP cord-015369-72cjogxz 3595 4 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 3595 5 mit mit NNP cord-015369-72cjogxz 3595 6 Patienten Patienten NNP cord-015369-72cjogxz 3595 7 , , , cord-015369-72cjogxz 3595 8 welche welche NNP cord-015369-72cjogxz 3595 9 , , , cord-015369-72cjogxz 3595 10 , , , cord-015369-72cjogxz 3595 11 liver liver NN cord-015369-72cjogxz 3595 12 first first RB cord-015369-72cjogxz 3595 13 ' ' '' cord-015369-72cjogxz 3595 14 ' ' '' cord-015369-72cjogxz 3595 15 therapiert therapiert NNP cord-015369-72cjogxz 3595 16 wurden wurden NNP cord-015369-72cjogxz 3596 1 und und NNP cord-015369-72cjogxz 3597 1 i -PRON- PRP cord-015369-72cjogxz 3597 2 m be VBP cord-015369-72cjogxz 3597 3 Falle Falle NNP cord-015369-72cjogxz 3597 4 eines eines NNP cord-015369-72cjogxz 3597 5 , , , cord-015369-72cjogxz 3597 6 , , , cord-015369-72cjogxz 3597 7 Response Response NNP cord-015369-72cjogxz 3597 8 ' ' '' cord-015369-72cjogxz 3597 9 ' ' `` cord-015369-72cjogxz 3597 10 auch auch FW cord-015369-72cjogxz 3597 11 das das NNP cord-015369-72cjogxz 3597 12 Primum Primum NNP cord-015369-72cjogxz 3597 13 eine eine NNP cord-015369-72cjogxz 3597 14 Regression Regression NNP cord-015369-72cjogxz 3597 15 zeigte zeigte NN cord-015369-72cjogxz 3597 16 . . . cord-015369-72cjogxz 3598 1 Sollte Sollte NNP cord-015369-72cjogxz 3598 2 somit somit NNP cord-015369-72cjogxz 3598 3 beim beim NNP cord-015369-72cjogxz 3598 4 metastasierten metastasierten NNP cord-015369-72cjogxz 3598 5 Rektumkarzinom Rektumkarzinom NNP cord-015369-72cjogxz 3598 6 auf auf NNP cord-015369-72cjogxz 3598 7 die die VBP cord-015369-72cjogxz 3598 8 scheinbar scheinbar NNP cord-015369-72cjogxz 3598 9 , , , cord-015369-72cjogxz 3598 10 , , , cord-015369-72cjogxz 3598 11 optimale optimale NNP cord-015369-72cjogxz 3598 12 ' ' POS cord-015369-72cjogxz 3598 13 ' ' `` cord-015369-72cjogxz 3598 14 neoadjuvante neoadjuvante FW cord-015369-72cjogxz 3599 1 Lokaltherapie Lokaltherapie NNP cord-015369-72cjogxz 3599 2 zugunsten zugunsten NNP cord-015369-72cjogxz 3600 1 einer einer NNP cord-015369-72cjogxz 3600 2 systemischen systemischen NNP cord-015369-72cjogxz 3600 3 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 3601 1 und und IN cord-015369-72cjogxz 3601 2 einer einer NNP cord-015369-72cjogxz 3601 3 , , , cord-015369-72cjogxz 3602 1 , , , cord-015369-72cjogxz 3602 2 liver liver NN cord-015369-72cjogxz 3602 3 first first RB cord-015369-72cjogxz 3602 4 ' ' '' cord-015369-72cjogxz 3602 5 ' ' '' cord-015369-72cjogxz 3603 1 Taktik Taktik NNP cord-015369-72cjogxz 3603 2 verzichtet verzichtet NNP cord-015369-72cjogxz 3603 3 werden werden NNP cord-015369-72cjogxz 3603 4 ? ? . cord-015369-72cjogxz 3604 1 Ist Ist NNP cord-015369-72cjogxz 3604 2 i -PRON- PRP cord-015369-72cjogxz 3604 3 m be VBP cord-015369-72cjogxz 3604 4 Falle Falle NNP cord-015369-72cjogxz 3604 5 eines eines NNP cord-015369-72cjogxz 3604 6 , , , cord-015369-72cjogxz 3604 7 , , , cord-015369-72cjogxz 3604 8 Response response NN cord-015369-72cjogxz 3604 9 ' ' '' cord-015369-72cjogxz 3604 10 ' ' '' cord-015369-72cjogxz 3605 1 auch auch NNP cord-015369-72cjogxz 3605 2 die die VBP cord-015369-72cjogxz 3605 3 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 3605 4 in in IN cord-015369-72cjogxz 3605 5 der der NNP cord-015369-72cjogxz 3605 6 Lage Lage NNP cord-015369-72cjogxz 3605 7 , , , cord-015369-72cjogxz 3605 8 eine eine NNP cord-015369-72cjogxz 3605 9 ausreichende ausreichende NNP cord-015369-72cjogxz 3605 10 Lokalkontrolle Lokalkontrolle NNP cord-015369-72cjogxz 3605 11 zu zu NNP cord-015369-72cjogxz 3605 12 gewährleisten gewährleisten NNP cord-015369-72cjogxz 3605 13 ? ? . cord-015369-72cjogxz 3606 1 Können können UH cord-015369-72cjogxz 3606 2 wir wir NNP cord-015369-72cjogxz 3606 3 Patienten Patienten NNP cord-015369-72cjogxz 3606 4 selektionieren selektionieren NNP cord-015369-72cjogxz 3606 5 , , , cord-015369-72cjogxz 3606 6 welche welche NNP cord-015369-72cjogxz 3606 7 unter unter NNP cord-015369-72cjogxz 3606 8 systemischer systemischer NNP cord-015369-72cjogxz 3607 1 Therapie Therapie NNP cord-015369-72cjogxz 3607 2 progredient progredient NNP cord-015369-72cjogxz 3607 3 sind sind NNP cord-015369-72cjogxz 3607 4 , , , cord-015369-72cjogxz 3607 5 und und NNP cord-015369-72cjogxz 3607 6 diesen diesen NNP cord-015369-72cjogxz 3607 7 die die VB cord-015369-72cjogxz 3607 8 neoadjuvante neoadjuvante NNP cord-015369-72cjogxz 3608 1 Lokaltherapie Lokaltherapie NNP cord-015369-72cjogxz 3608 2 und und IN cord-015369-72cjogxz 3608 3 Operation Operation NNP cord-015369-72cjogxz 3608 4 ersparen ersparen NNP cord-015369-72cjogxz 3608 5 ? ? . cord-015369-72cjogxz 3609 1 Bis Bis NNP cord-015369-72cjogxz 3609 2 dato dato NNP cord-015369-72cjogxz 3609 3 bleibt bleibt NNP cord-015369-72cjogxz 3609 4 die die VBP cord-015369-72cjogxz 3609 5 Behandlungsstrategie Behandlungsstrategie NNP cord-015369-72cjogxz 3609 6 beim beim NNP cord-015369-72cjogxz 3609 7 synchron synchron NNP cord-015369-72cjogxz 3609 8 metastasierten metastasierten NNP cord-015369-72cjogxz 3609 9 Rektumkarzinom Rektumkarzinom NNP cord-015369-72cjogxz 3609 10 kontrovers kontrover NNS cord-015369-72cjogxz 3609 11 . . . cord-015369-72cjogxz 3610 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 3610 2 . . . cord-015369-72cjogxz 3611 1 Insgesamt Insgesamt NNP cord-015369-72cjogxz 3611 2 entwickelten entwickelten NNP cord-015369-72cjogxz 3611 3 33 33 CD cord-015369-72cjogxz 3611 4 % % NN cord-015369-72cjogxz 3611 5 der der NNP cord-015369-72cjogxz 3611 6 Patienten Patienten NNP cord-015369-72cjogxz 3611 7 ein ein NNP cord-015369-72cjogxz 3611 8 Tumorrezidiv Tumorrezidiv NNP cord-015369-72cjogxz 3611 9 , , , cord-015369-72cjogxz 3611 10 während während JJ cord-015369-72cjogxz 3611 11 67 67 CD cord-015369-72cjogxz 3611 12 % % NN cord-015369-72cjogxz 3611 13 rezidivfrei rezidivfrei NN cord-015369-72cjogxz 3611 14 blieben blieben NNP cord-015369-72cjogxz 3611 15 ( ( -LRB- cord-015369-72cjogxz 3611 16 10-Jahres 10-jahres CD cord-015369-72cjogxz 3611 17 - - HYPH cord-015369-72cjogxz 3611 18 krankheitsfreie krankheitsfreie NN cord-015369-72cjogxz 3611 19 - - HYPH cord-015369-72cjogxz 3611 20 Ü Ü NNP cord-015369-72cjogxz 3611 21 berlebensrate berlebensrate NN cord-015369-72cjogxz 3611 22 : : : cord-015369-72cjogxz 3611 23 63 63 CD cord-015369-72cjogxz 3611 24 % % NN cord-015369-72cjogxz 3611 25 ) ) -RRB- cord-015369-72cjogxz 3611 26 . . . cord-015369-72cjogxz 3612 1 Die die VB cord-015369-72cjogxz 3612 2 in in IN cord-015369-72cjogxz 3612 3 der der NNP cord-015369-72cjogxz 3612 4 Nachsorge Nachsorge NNP cord-015369-72cjogxz 3612 5 diagnostizierten diagnostizierten NNP cord-015369-72cjogxz 3613 1 asymptomatischen asymptomatischen NNP cord-015369-72cjogxz 3613 2 Rezidive Rezidive NNP cord-015369-72cjogxz 3613 3 traten traten VBD cord-015369-72cjogxz 3613 4 bis bis NNP cord-015369-72cjogxz 3613 5 8 8 CD cord-015369-72cjogxz 3613 6 Jahre Jahre NNP cord-015369-72cjogxz 3613 7 nach nach NNP cord-015369-72cjogxz 3613 8 Primärbehandlung Primärbehandlung NNP cord-015369-72cjogxz 3613 9 auf auf NNP cord-015369-72cjogxz 3613 10 ; ; : cord-015369-72cjogxz 3613 11 nahezu nahezu NNP cord-015369-72cjogxz 3613 12 die die VBP cord-015369-72cjogxz 3613 13 Hälfte Hälfte NNP cord-015369-72cjogxz 3613 14 ( ( -LRB- cord-015369-72cjogxz 3613 15 22/48 22/48 CD cord-015369-72cjogxz 3613 16 ; ; : cord-015369-72cjogxz 3613 17 46 46 CD cord-015369-72cjogxz 3613 18 % % NN cord-015369-72cjogxz 3613 19 ) ) -RRB- cord-015369-72cjogxz 3614 1 dieser dieser NNP cord-015369-72cjogxz 3614 2 Patienten Patienten NNP cord-015369-72cjogxz 3614 3 konnte konnte NNP cord-015369-72cjogxz 3614 4 in in IN cord-015369-72cjogxz 3614 5 kurativer kurativer NNP cord-015369-72cjogxz 3614 6 Absicht Absicht NNP cord-015369-72cjogxz 3614 7 re re NN cord-015369-72cjogxz 3614 8 - - NN cord-015369-72cjogxz 3614 9 operiert operiert JJ cord-015369-72cjogxz 3614 10 werden werden NNP cord-015369-72cjogxz 3614 11 . . . cord-015369-72cjogxz 3615 1 Davon Davon NNP cord-015369-72cjogxz 3615 2 blieben blieben NN cord-015369-72cjogxz 3615 3 41 41 CD cord-015369-72cjogxz 3615 4 % % NN cord-015369-72cjogxz 3615 5 ( ( -LRB- cord-015369-72cjogxz 3615 6 9/22 9/22 CD cord-015369-72cjogxz 3615 7 ) ) -RRB- cord-015369-72cjogxz 3615 8 innerhalb innerhalb NNP cord-015369-72cjogxz 3615 9 der der NNP cord-015369-72cjogxz 3615 10 Nachbeobachtung Nachbeobachtung NNP cord-015369-72cjogxz 3615 11 rezidivfrei rezidivfrei NN cord-015369-72cjogxz 3615 12 . . . cord-015369-72cjogxz 3616 1 In in IN cord-015369-72cjogxz 3616 2 einer einer NNP cord-015369-72cjogxz 3616 3 multivariaten multivariaten NNP cord-015369-72cjogxz 3616 4 Analyse Analyse NNP cord-015369-72cjogxz 3616 5 zeigten zeigten NNP cord-015369-72cjogxz 3616 6 das das NNP cord-015369-72cjogxz 3616 7 UICC UICC NNP cord-015369-72cjogxz 3616 8 - - HYPH cord-015369-72cjogxz 3616 9 Stadium Stadium NNP cord-015369-72cjogxz 3616 10 ( ( -LRB- cord-015369-72cjogxz 3616 11 p p NN cord-015369-72cjogxz 3616 12 ¼ ¼ CD cord-015369-72cjogxz 3616 13 0.000 0.000 CD cord-015369-72cjogxz 3616 14 ) ) -RRB- cord-015369-72cjogxz 3616 15 und und NNP cord-015369-72cjogxz 3616 16 das das NNP cord-015369-72cjogxz 3616 17 Grading Grading NNP cord-015369-72cjogxz 3616 18 ( ( -LRB- cord-015369-72cjogxz 3616 19 p p NN cord-015369-72cjogxz 3616 20 < < XX cord-015369-72cjogxz 3616 21 0.05 0.05 CD cord-015369-72cjogxz 3616 22 ) ) -RRB- cord-015369-72cjogxz 3616 23 eine eine NNP cord-015369-72cjogxz 3616 24 signifikante signifikante JJ cord-015369-72cjogxz 3616 25 Korrelation Korrelation NNP cord-015369-72cjogxz 3616 26 zum zum NNP cord-015369-72cjogxz 3616 27 Rezidivauftreten Rezidivauftreten NNP cord-015369-72cjogxz 3616 28 . . . cord-015369-72cjogxz 3617 1 Die die VB cord-015369-72cjogxz 3617 2 5-und 5-und JJ cord-015369-72cjogxz 3617 3 10-Jahres 10-jahres CD cord-015369-72cjogxz 3617 4 - - HYPH cord-015369-72cjogxz 3617 5 Ü ü NN cord-015369-72cjogxz 3617 6 berlebensraten berlebensraten NNP cord-015369-72cjogxz 3617 7 dieses dieses NNP cord-015369-72cjogxz 3617 8 Kollektivs Kollektivs NNP cord-015369-72cjogxz 3617 9 waren waren NNP cord-015369-72cjogxz 3617 10 74 74 CD cord-015369-72cjogxz 3617 11 % % NN cord-015369-72cjogxz 3617 12 bzw bzw NNP cord-015369-72cjogxz 3617 13 . . . cord-015369-72cjogxz 3618 1 60 60 CD cord-015369-72cjogxz 3618 2 % % NN cord-015369-72cjogxz 3618 3 . . . cord-015369-72cjogxz 3619 1 In in IN cord-015369-72cjogxz 3619 2 Bezug Bezug NNP cord-015369-72cjogxz 3619 3 auf auf NNP cord-015369-72cjogxz 3619 4 das das NNP cord-015369-72cjogxz 3619 5 Ü Ü NNP cord-015369-72cjogxz 3619 6 berleben berleben NNP cord-015369-72cjogxz 3619 7 war war NN cord-015369-72cjogxz 3619 8 in in IN cord-015369-72cjogxz 3619 9 der der NNP cord-015369-72cjogxz 3619 10 multivariaten multivariaten NNP cord-015369-72cjogxz 3620 1 Analyse analyse VB cord-015369-72cjogxz 3620 2 nur nur FW cord-015369-72cjogxz 3620 3 das das NNP cord-015369-72cjogxz 3620 4 ypT ypT NNP cord-015369-72cjogxz 3620 5 - - HYPH cord-015369-72cjogxz 3620 6 Stadium Stadium NNP cord-015369-72cjogxz 3620 7 ( ( -LRB- cord-015369-72cjogxz 3620 8 p p NN cord-015369-72cjogxz 3620 9 < < XX cord-015369-72cjogxz 3620 10 0.01 0.01 CD cord-015369-72cjogxz 3620 11 ) ) -RRB- cord-015369-72cjogxz 3621 1 ein ein NNP cord-015369-72cjogxz 3621 2 signifikanter signifikanter NNP cord-015369-72cjogxz 3621 3 Parameter Parameter NNP cord-015369-72cjogxz 3621 4 . . . cord-015369-72cjogxz 3622 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 3622 2 . . . cord-015369-72cjogxz 3623 1 Bei Bei NNP cord-015369-72cjogxz 3623 2 Patienten Patienten NNP cord-015369-72cjogxz 3623 3 mit mit XX cord-015369-72cjogxz 3624 1 lokal lokal NNP cord-015369-72cjogxz 3624 2 fortgeschrittenem fortgeschrittenem NNP cord-015369-72cjogxz 3624 3 Rektumkarzinom Rektumkarzinom NNP cord-015369-72cjogxz 3624 4 können können NNP cord-015369-72cjogxz 3624 5 gute gute NNP cord-015369-72cjogxz 3625 1 onkologische onkologische NNP cord-015369-72cjogxz 3625 2 Langzeitergebnisse Langzeitergebnisse NNP cord-015369-72cjogxz 3625 3 erzielt erzielt NNS cord-015369-72cjogxz 3625 4 werden werden NNP cord-015369-72cjogxz 3625 5 . . . cord-015369-72cjogxz 3626 1 Dazu dazu UH cord-015369-72cjogxz 3626 2 ist ist NNP cord-015369-72cjogxz 3626 3 neben neben NNP cord-015369-72cjogxz 3626 4 der der NNP cord-015369-72cjogxz 3626 5 multimodalen multimodalen NNP cord-015369-72cjogxz 3626 6 Therapie Therapie NNP cord-015369-72cjogxz 3626 7 auch auch NNP cord-015369-72cjogxz 3626 8 ein ein NNP cord-015369-72cjogxz 3626 9 intensives intensive NNS cord-015369-72cjogxz 3626 10 Nachsorgeprogramm Nachsorgeprogramm NNP cord-015369-72cjogxz 3626 11 notwendig notwendig NNP cord-015369-72cjogxz 3626 12 , , , cord-015369-72cjogxz 3626 13 welches welches NNP cord-015369-72cjogxz 3626 14 asymptomatische asymptomatische NNP cord-015369-72cjogxz 3626 15 Rezidive Rezidive NNP cord-015369-72cjogxz 3627 1 frühzeitig frühzeitig NNP cord-015369-72cjogxz 3627 2 erkennen erkennen NNP cord-015369-72cjogxz 3627 3 lässt lässt NNP cord-015369-72cjogxz 3628 1 und und IN cord-015369-72cjogxz 3628 2 kurative kurative NNP cord-015369-72cjogxz 3628 3 Re Re NNP cord-015369-72cjogxz 3628 4 - - NNP cord-015369-72cjogxz 3628 5 Operationen Operationen NNP cord-015369-72cjogxz 3628 6 ermöglicht ermöglicht NNP cord-015369-72cjogxz 3628 7 . . . cord-015369-72cjogxz 3629 1 Background background NN cord-015369-72cjogxz 3629 2 . . . cord-015369-72cjogxz 3630 1 Transcatheter Transcatheter NNP cord-015369-72cjogxz 3630 2 based base VBN cord-015369-72cjogxz 3630 3 aortic aortic JJ cord-015369-72cjogxz 3630 4 valve valve NN cord-015369-72cjogxz 3630 5 replacement replacement NN cord-015369-72cjogxz 3630 6 ( ( -LRB- cord-015369-72cjogxz 3630 7 AVR AVR NNP cord-015369-72cjogxz 3630 8 ) ) -RRB- cord-015369-72cjogxz 3630 9 is be VBZ cord-015369-72cjogxz 3630 10 a a DT cord-015369-72cjogxz 3630 11 promising promising JJ cord-015369-72cjogxz 3630 12 procedure procedure NN cord-015369-72cjogxz 3630 13 to to TO cord-015369-72cjogxz 3630 14 reduce reduce VB cord-015369-72cjogxz 3630 15 operative operative JJ cord-015369-72cjogxz 3630 16 risk risk NN cord-015369-72cjogxz 3630 17 especially especially RB cord-015369-72cjogxz 3630 18 in in IN cord-015369-72cjogxz 3630 19 old old JJ cord-015369-72cjogxz 3630 20 patients patient NNS cord-015369-72cjogxz 3630 21 with with IN cord-015369-72cjogxz 3630 22 significant significant JJ cord-015369-72cjogxz 3630 23 comorbidities comorbiditie NNS cord-015369-72cjogxz 3630 24 . . . cord-015369-72cjogxz 3631 1 We -PRON- PRP cord-015369-72cjogxz 3631 2 report report VBP cord-015369-72cjogxz 3631 3 the the DT cord-015369-72cjogxz 3631 4 initial initial JJ cord-015369-72cjogxz 3631 5 series series NN cord-015369-72cjogxz 3631 6 of of IN cord-015369-72cjogxz 3631 7 transapical transapical JJ cord-015369-72cjogxz 3631 8 and and CC cord-015369-72cjogxz 3631 9 transfemoral transfemoral NNP cord-015369-72cjogxz 3631 10 - - HYPH cord-015369-72cjogxz 3631 11 AVR AVR NNP cord-015369-72cjogxz 3631 12 including include VBG cord-015369-72cjogxz 3631 13 3 3 CD cord-015369-72cjogxz 3631 14 years year NNS cord-015369-72cjogxz 3631 15 follow follow VB cord-015369-72cjogxz 3631 16 up up RP cord-015369-72cjogxz 3631 17 . . . cord-015369-72cjogxz 3632 1 Methods method NNS cord-015369-72cjogxz 3632 2 . . . cord-015369-72cjogxz 3633 1 Access Access NNP cord-015369-72cjogxz 3633 2 was be VBD cord-015369-72cjogxz 3633 3 either either RB cord-015369-72cjogxz 3633 4 antegrade antegrade VBN cord-015369-72cjogxz 3633 5 through through IN cord-015369-72cjogxz 3633 6 a a DT cord-015369-72cjogxz 3633 7 anterolateral anterolateral JJ cord-015369-72cjogxz 3633 8 thoracotomy thoracotomy NN cord-015369-72cjogxz 3633 9 with with IN cord-015369-72cjogxz 3633 10 direct direct JJ cord-015369-72cjogxz 3633 11 puncture puncture NN cord-015369-72cjogxz 3633 12 of of IN cord-015369-72cjogxz 3633 13 the the DT cord-015369-72cjogxz 3633 14 apex apex JJ cord-015369-72cjogxz 3633 15 or or CC cord-015369-72cjogxz 3633 16 retrograde retrograde JJ cord-015369-72cjogxz 3633 17 through through IN cord-015369-72cjogxz 3633 18 the the DT cord-015369-72cjogxz 3633 19 femoral femoral JJ cord-015369-72cjogxz 3633 20 artery artery NN cord-015369-72cjogxz 3633 21 . . . cord-015369-72cjogxz 3634 1 After after IN cord-015369-72cjogxz 3634 2 initial initial JJ cord-015369-72cjogxz 3634 3 balloon balloon NN cord-015369-72cjogxz 3634 4 - - HYPH cord-015369-72cjogxz 3634 5 valvuloplasty valvuloplasty NN cord-015369-72cjogxz 3634 6 the the DT cord-015369-72cjogxz 3634 7 balloon balloon NN cord-015369-72cjogxz 3634 8 - - HYPH cord-015369-72cjogxz 3634 9 mounted mount VBN cord-015369-72cjogxz 3634 10 crimped crimped JJ cord-015369-72cjogxz 3634 11 bioprosthesis bioprosthesis NNP cord-015369-72cjogxz 3634 12 was be VBD cord-015369-72cjogxz 3634 13 introduced introduce VBN cord-015369-72cjogxz 3634 14 and and CC cord-015369-72cjogxz 3634 15 positioned position VBN cord-015369-72cjogxz 3634 16 under under IN cord-015369-72cjogxz 3634 17 fluoroscopic fluoroscopic NN cord-015369-72cjogxz 3634 18 and and CC cord-015369-72cjogxz 3634 19 echo echo NN cord-015369-72cjogxz 3634 20 control control NN cord-015369-72cjogxz 3634 21 . . . cord-015369-72cjogxz 3635 1 Since since IN cord-015369-72cjogxz 3635 2 March March NNP cord-015369-72cjogxz 3635 3 2006 2006 CD cord-015369-72cjogxz 3635 4 fifty fifty CD cord-015369-72cjogxz 3635 5 - - HYPH cord-015369-72cjogxz 3635 6 nine nine CD cord-015369-72cjogxz 3635 7 patients patient NNS cord-015369-72cjogxz 3635 8 underwent undergo VBD cord-015369-72cjogxz 3635 9 transapical transapical JJ cord-015369-72cjogxz 3635 10 - - HYPH cord-015369-72cjogxz 3635 11 AVR AVR NNP cord-015369-72cjogxz 3635 12 and and CC cord-015369-72cjogxz 3635 13 34 34 CD cord-015369-72cjogxz 3635 14 patients patient NNS cord-015369-72cjogxz 3635 15 underwent undergo VBD cord-015369-72cjogxz 3635 16 transfemoral transfemoral NNP cord-015369-72cjogxz 3635 17 - - HYPH cord-015369-72cjogxz 3635 18 AVR AVR NNP cord-015369-72cjogxz 3635 19 . . . cord-015369-72cjogxz 3636 1 Mean mean JJ cord-015369-72cjogxz 3636 2 age age NN cord-015369-72cjogxz 3636 3 was be VBD cord-015369-72cjogxz 3636 4 82 82 CD cord-015369-72cjogxz 3636 5 AE AE NNP cord-015369-72cjogxz 3636 6 5.5 5.5 CD cord-015369-72cjogxz 3636 7 years year NNS cord-015369-72cjogxz 3636 8 , , , cord-015369-72cjogxz 3636 9 the the DT cord-015369-72cjogxz 3636 10 logistic logistic JJ cord-015369-72cjogxz 3636 11 EuroScore EuroScore NNP cord-015369-72cjogxz 3636 12 predicted predict VBD cord-015369-72cjogxz 3636 13 risk risk NN cord-015369-72cjogxz 3636 14 for for IN cord-015369-72cjogxz 3636 15 mortality mortality NN cord-015369-72cjogxz 3636 16 was be VBD cord-015369-72cjogxz 3636 17 26.3 26.3 CD cord-015369-72cjogxz 3636 18 AE AE NNP cord-015369-72cjogxz 3636 19 15.7 15.7 CD cord-015369-72cjogxz 3636 20 % % NN cord-015369-72cjogxz 3636 21 . . . cord-015369-72cjogxz 3637 1 Results result NNS cord-015369-72cjogxz 3637 2 . . . cord-015369-72cjogxz 3638 1 Implantation implantation NN cord-015369-72cjogxz 3638 2 was be VBD cord-015369-72cjogxz 3638 3 performed perform VBN cord-015369-72cjogxz 3638 4 on on IN cord-015369-72cjogxz 3638 5 beating beat VBG cord-015369-72cjogxz 3638 6 heart heart NN cord-015369-72cjogxz 3638 7 with with IN cord-015369-72cjogxz 3638 8 a a DT cord-015369-72cjogxz 3638 9 period period NN cord-015369-72cjogxz 3638 10 of of IN cord-015369-72cjogxz 3638 11 rapid rapid JJ cord-015369-72cjogxz 3638 12 pacing pacing NN cord-015369-72cjogxz 3638 13 for for IN cord-015369-72cjogxz 3638 14 deployment deployment NN cord-015369-72cjogxz 3638 15 of of IN cord-015369-72cjogxz 3638 16 the the DT cord-015369-72cjogxz 3638 17 valve valve NN cord-015369-72cjogxz 3638 18 . . . cord-015369-72cjogxz 3639 1 Cardiopulmonary cardiopulmonary JJ cord-015369-72cjogxz 3639 2 bypass bypass NN cord-015369-72cjogxz 3639 3 was be VBD cord-015369-72cjogxz 3639 4 used use VBN cord-015369-72cjogxz 3639 5 only only RB cord-015369-72cjogxz 3639 6 in in IN cord-015369-72cjogxz 3639 7 the the DT cord-015369-72cjogxz 3639 8 initial initial JJ cord-015369-72cjogxz 3639 9 7 7 CD cord-015369-72cjogxz 3639 10 patients patient NNS cord-015369-72cjogxz 3639 11 . . . cord-015369-72cjogxz 3640 1 In in IN cord-015369-72cjogxz 3640 2 the the DT cord-015369-72cjogxz 3640 3 transapical transapical JJ cord-015369-72cjogxz 3640 4 group group NN cord-015369-72cjogxz 3640 5 4 4 CD cord-015369-72cjogxz 3640 6 patients patient NNS cord-015369-72cjogxz 3640 7 had have VBD cord-015369-72cjogxz 3640 8 to to TO cord-015369-72cjogxz 3640 9 be be VB cord-015369-72cjogxz 3640 10 converted convert VBN cord-015369-72cjogxz 3640 11 to to IN cord-015369-72cjogxz 3640 12 conventional conventional JJ cord-015369-72cjogxz 3640 13 AVR avr NN cord-015369-72cjogxz 3640 14 because because IN cord-015369-72cjogxz 3640 15 of of IN cord-015369-72cjogxz 3640 16 malpositioning malpositioning NN cord-015369-72cjogxz 3640 17 . . . cord-015369-72cjogxz 3641 1 Thirty thirty CD cord-015369-72cjogxz 3641 2 days day NNS cord-015369-72cjogxz 3641 3 mortality mortality NN cord-015369-72cjogxz 3641 4 for for IN cord-015369-72cjogxz 3641 5 transapical transapical NN cord-015369-72cjogxz 3641 6 was be VBD cord-015369-72cjogxz 3641 7 13 13 CD cord-015369-72cjogxz 3641 8 % % NN cord-015369-72cjogxz 3641 9 , , , cord-015369-72cjogxz 3641 10 in in IN cord-015369-72cjogxz 3641 11 the the DT cord-015369-72cjogxz 3641 12 transfemoral transfemoral NNP cord-015369-72cjogxz 3641 13 group group NNP cord-015369-72cjogxz 3641 14 5 5 CD cord-015369-72cjogxz 3641 15 % % NN cord-015369-72cjogxz 3641 16 . . . cord-015369-72cjogxz 3642 1 Echocardiography echocardiography NN cord-015369-72cjogxz 3642 2 showed show VBD cord-015369-72cjogxz 3642 3 excellent excellent JJ cord-015369-72cjogxz 3642 4 gradients gradient NNS cord-015369-72cjogxz 3642 5 ( ( -LRB- cord-015369-72cjogxz 3642 6 pmax pmax NNP cord-015369-72cjogxz 3642 7 19.3 19.3 CD cord-015369-72cjogxz 3642 8 AE AE NNP cord-015369-72cjogxz 3642 9 12 12 CD cord-015369-72cjogxz 3642 10 mmHg mmHg NNS cord-015369-72cjogxz 3642 11 ) ) -RRB- cord-015369-72cjogxz 3642 12 at at IN cord-015369-72cjogxz 3642 13 discharge discharge NN cord-015369-72cjogxz 3642 14 and and CC cord-015369-72cjogxz 3642 15 3 3 CD cord-015369-72cjogxz 3642 16 years year NNS cord-015369-72cjogxz 3642 17 after after IN cord-015369-72cjogxz 3642 18 implantation implantation NN cord-015369-72cjogxz 3642 19 . . . cord-015369-72cjogxz 3643 1 Small small JJ cord-015369-72cjogxz 3643 2 paravalvular paravalvular JJ cord-015369-72cjogxz 3643 3 leaks leak NNS cord-015369-72cjogxz 3643 4 without without IN cord-015369-72cjogxz 3643 5 hemodynamic hemodynamic JJ cord-015369-72cjogxz 3643 6 importance importance NN cord-015369-72cjogxz 3643 7 were be VBD cord-015369-72cjogxz 3643 8 observed observe VBN cord-015369-72cjogxz 3643 9 in in IN cord-015369-72cjogxz 3643 10 27 27 CD cord-015369-72cjogxz 3643 11 patients patient NNS cord-015369-72cjogxz 3643 12 ( ( -LRB- cord-015369-72cjogxz 3643 13 45 45 CD cord-015369-72cjogxz 3643 14 % % NN cord-015369-72cjogxz 3643 15 ) ) -RRB- cord-015369-72cjogxz 3643 16 in in IN cord-015369-72cjogxz 3643 17 the the DT cord-015369-72cjogxz 3643 18 transapical transapical JJ cord-015369-72cjogxz 3643 19 group group NN cord-015369-72cjogxz 3643 20 and and CC cord-015369-72cjogxz 3643 21 in in IN cord-015369-72cjogxz 3643 22 all all DT cord-015369-72cjogxz 3643 23 transfemoral transfemoral JJ cord-015369-72cjogxz 3643 24 patients patient NNS cord-015369-72cjogxz 3643 25 . . . cord-015369-72cjogxz 3644 1 Conclusions conclusion NNS cord-015369-72cjogxz 3644 2 . . . cord-015369-72cjogxz 3645 1 Transcatheter Transcatheter NNP cord-015369-72cjogxz 3645 2 AVR AVR NNP cord-015369-72cjogxz 3645 3 with with IN cord-015369-72cjogxz 3645 4 the the DT cord-015369-72cjogxz 3645 5 Sapien Sapien NNP cord-015369-72cjogxz 3645 6 - - HYPH cord-015369-72cjogxz 3645 7 Edwards Edwards NNP cord-015369-72cjogxz 3645 8 bioprosthesis bioprosthesis NN cord-015369-72cjogxz 3645 9 can can MD cord-015369-72cjogxz 3645 10 be be VB cord-015369-72cjogxz 3645 11 performed perform VBN cord-015369-72cjogxz 3645 12 in in IN cord-015369-72cjogxz 3645 13 high high JJ cord-015369-72cjogxz 3645 14 risk risk NN cord-015369-72cjogxz 3645 15 patients patient NNS cord-015369-72cjogxz 3645 16 successfully successfully RB cord-015369-72cjogxz 3645 17 . . . cord-015369-72cjogxz 3646 1 Complications complication NNS cord-015369-72cjogxz 3646 2 may may MD cord-015369-72cjogxz 3646 3 be be VB cord-015369-72cjogxz 3646 4 attributed attribute VBN cord-015369-72cjogxz 3646 5 to to IN cord-015369-72cjogxz 3646 6 the the DT cord-015369-72cjogxz 3646 7 high high JJ cord-015369-72cjogxz 3646 8 risk risk NN cord-015369-72cjogxz 3646 9 profile profile NN cord-015369-72cjogxz 3646 10 of of IN cord-015369-72cjogxz 3646 11 the the DT cord-015369-72cjogxz 3646 12 elderly elderly JJ cord-015369-72cjogxz 3646 13 patients patient NNS cord-015369-72cjogxz 3646 14 and and CC cord-015369-72cjogxz 3646 15 the the DT cord-015369-72cjogxz 3646 16 learning learning NN cord-015369-72cjogxz 3646 17 curve curve NN cord-015369-72cjogxz 3646 18 of of IN cord-015369-72cjogxz 3646 19 this this DT cord-015369-72cjogxz 3646 20 new new JJ cord-015369-72cjogxz 3646 21 procedure procedure NN cord-015369-72cjogxz 3646 22 . . . cord-015369-72cjogxz 3647 1 The the DT cord-015369-72cjogxz 3647 2 valve valve NN cord-015369-72cjogxz 3647 3 exhibits exhibit VBZ cord-015369-72cjogxz 3647 4 excellent excellent JJ cord-015369-72cjogxz 3647 5 hemodynamics hemodynamic NNS cord-015369-72cjogxz 3647 6 up up IN cord-015369-72cjogxz 3647 7 to to IN cord-015369-72cjogxz 3647 8 3 3 CD cord-015369-72cjogxz 3647 9 years year NNS cord-015369-72cjogxz 3647 10 . . . cord-015369-72cjogxz 3648 1 However however RB cord-015369-72cjogxz 3648 2 , , , cord-015369-72cjogxz 3648 3 longer long JJR cord-015369-72cjogxz 3648 4 - - HYPH cord-015369-72cjogxz 3648 5 term term NN cord-015369-72cjogxz 3648 6 valve valve NN cord-015369-72cjogxz 3648 7 performance performance NN cord-015369-72cjogxz 3648 8 and and CC cord-015369-72cjogxz 3648 9 durability durability NN cord-015369-72cjogxz 3648 10 needs need VBZ cord-015369-72cjogxz 3648 11 to to TO cord-015369-72cjogxz 3648 12 be be VB cord-015369-72cjogxz 3648 13 monitored monitor VBN cord-015369-72cjogxz 3648 14 . . . cord-015369-72cjogxz 3649 1 Drei Drei NNP cord-015369-72cjogxz 3649 2 herzchirurgische herzchirurgische NN cord-015369-72cjogxz 3649 3 Notfälle Notfälle NNP cord-015369-72cjogxz 3649 4 nach nach NNP cord-015369-72cjogxz 3649 5 50 50 CD cord-015369-72cjogxz 3649 6 percutanen percutanen NN cord-015369-72cjogxz 3649 7 Aortenklappenimplantationen Aortenklappenimplantationen NNP cord-015369-72cjogxz 3649 8 Background Background NNP cord-015369-72cjogxz 3649 9 . . . cord-015369-72cjogxz 3650 1 In in IN cord-015369-72cjogxz 3650 2 symptomatic symptomatic JJ cord-015369-72cjogxz 3650 3 patients patient NNS cord-015369-72cjogxz 3650 4 with with IN cord-015369-72cjogxz 3650 5 severe severe JJ cord-015369-72cjogxz 3650 6 aortic aortic JJ cord-015369-72cjogxz 3650 7 stenosis stenosis NN cord-015369-72cjogxz 3650 8 ( ( -LRB- cord-015369-72cjogxz 3650 9 AS as RB cord-015369-72cjogxz 3650 10 ) ) -RRB- cord-015369-72cjogxz 3650 11 , , , cord-015369-72cjogxz 3650 12 operative operative JJ cord-015369-72cjogxz 3650 13 aortic aortic JJ cord-015369-72cjogxz 3650 14 valve valve NN cord-015369-72cjogxz 3650 15 replacement replacement NN cord-015369-72cjogxz 3650 16 is be VBZ cord-015369-72cjogxz 3650 17 the the DT cord-015369-72cjogxz 3650 18 treatment treatment NN cord-015369-72cjogxz 3650 19 of of IN cord-015369-72cjogxz 3650 20 choice choice NN cord-015369-72cjogxz 3650 21 . . . cord-015369-72cjogxz 3651 1 However however RB cord-015369-72cjogxz 3651 2 , , , cord-015369-72cjogxz 3651 3 not not RB cord-015369-72cjogxz 3651 4 only only RB cord-015369-72cjogxz 3651 5 symptomatic symptomatic JJ cord-015369-72cjogxz 3651 6 AS AS NNP cord-015369-72cjogxz 3651 7 becomes become VBZ cord-015369-72cjogxz 3651 8 more more RBR cord-015369-72cjogxz 3651 9 prevalent prevalent JJ cord-015369-72cjogxz 3651 10 in in IN cord-015369-72cjogxz 3651 11 elderly elderly JJ cord-015369-72cjogxz 3651 12 patients patient NNS cord-015369-72cjogxz 3651 13 but but CC cord-015369-72cjogxz 3651 14 also also RB cord-015369-72cjogxz 3651 15 comorbidities comorbiditie NNS cord-015369-72cjogxz 3651 16 that that WDT cord-015369-72cjogxz 3651 17 increase increase VBP cord-015369-72cjogxz 3651 18 the the DT cord-015369-72cjogxz 3651 19 risk risk NN cord-015369-72cjogxz 3651 20 for for IN cord-015369-72cjogxz 3651 21 operative operative JJ cord-015369-72cjogxz 3651 22 valve valve NN cord-015369-72cjogxz 3651 23 replacement replacement NN cord-015369-72cjogxz 3651 24 . . . cord-015369-72cjogxz 3652 1 Therefore therefore RB cord-015369-72cjogxz 3652 2 , , , cord-015369-72cjogxz 3652 3 percutaneous percutaneous JJ cord-015369-72cjogxz 3652 4 aortic aortic JJ cord-015369-72cjogxz 3652 5 valve valve NN cord-015369-72cjogxz 3652 6 replacement replacement NN cord-015369-72cjogxz 3652 7 ( ( -LRB- cord-015369-72cjogxz 3652 8 PAVR PAVR NNP cord-015369-72cjogxz 3652 9 ) ) -RRB- cord-015369-72cjogxz 3652 10 might may MD cord-015369-72cjogxz 3652 11 be be VB cord-015369-72cjogxz 3652 12 an an DT cord-015369-72cjogxz 3652 13 alternative alternative JJ cord-015369-72cjogxz 3652 14 therapy therapy NN cord-015369-72cjogxz 3652 15 for for IN cord-015369-72cjogxz 3652 16 high high JJ cord-015369-72cjogxz 3652 17 - - HYPH cord-015369-72cjogxz 3652 18 risk risk NN cord-015369-72cjogxz 3652 19 patients patient NNS cord-015369-72cjogxz 3652 20 . . . cord-015369-72cjogxz 3653 1 Methods method NNS cord-015369-72cjogxz 3653 2 . . . cord-015369-72cjogxz 3654 1 In in IN cord-015369-72cjogxz 3654 2 our -PRON- PRP$ cord-015369-72cjogxz 3654 3 institution institution NN cord-015369-72cjogxz 3654 4 , , , cord-015369-72cjogxz 3654 5 53 53 CD cord-015369-72cjogxz 3654 6 patients patient NNS cord-015369-72cjogxz 3654 7 ( ( -LRB- cord-015369-72cjogxz 3654 8 19 19 CD cord-015369-72cjogxz 3654 9 male male NN cord-015369-72cjogxz 3654 10 , , , cord-015369-72cjogxz 3654 11 34 34 CD cord-015369-72cjogxz 3654 12 female female JJ cord-015369-72cjogxz 3654 13 ; ; : cord-015369-72cjogxz 3654 14 mean mean VB cord-015369-72cjogxz 3654 15 age age NN cord-015369-72cjogxz 3654 16 80 80 CD cord-015369-72cjogxz 3654 17 AE AE NNP cord-015369-72cjogxz 3654 18 6 6 CD cord-015369-72cjogxz 3654 19 years year NNS cord-015369-72cjogxz 3654 20 ) ) -RRB- cord-015369-72cjogxz 3654 21 with with IN cord-015369-72cjogxz 3654 22 symptomatic symptomatic JJ cord-015369-72cjogxz 3654 23 severe severe JJ cord-015369-72cjogxz 3654 24 AS as NN cord-015369-72cjogxz 3654 25 and and CC cord-015369-72cjogxz 3654 26 a a DT cord-015369-72cjogxz 3654 27 logistic logistic JJ cord-015369-72cjogxz 3654 28 EuroSCORE EuroSCORE NNP cord-015369-72cjogxz 3654 29 > > XX cord-015369-72cjogxz 3654 30 20 20 CD cord-015369-72cjogxz 3654 31 % % NN cord-015369-72cjogxz 3654 32 underwent undergo VBD cord-015369-72cjogxz 3654 33 PAVR PAVR NNP cord-015369-72cjogxz 3654 34 between between IN cord-015369-72cjogxz 3654 35 May May NNP cord-015369-72cjogxz 3654 36 2007 2007 CD cord-015369-72cjogxz 3654 37 and and CC cord-015369-72cjogxz 3654 38 January January NNP cord-015369-72cjogxz 3654 39 2009 2009 CD cord-015369-72cjogxz 3654 40 . . . cord-015369-72cjogxz 3655 1 The the DT cord-015369-72cjogxz 3655 2 procedure procedure NN cord-015369-72cjogxz 3655 3 was be VBD cord-015369-72cjogxz 3655 4 performed perform VBN cord-015369-72cjogxz 3655 5 in in IN cord-015369-72cjogxz 3655 6 the the DT cord-015369-72cjogxz 3655 7 catheterization catheterization NN cord-015369-72cjogxz 3655 8 laboratory laboratory NN cord-015369-72cjogxz 3655 9 via via IN cord-015369-72cjogxz 3655 10 a a DT cord-015369-72cjogxz 3655 11 bifemoral bifemoral JJ cord-015369-72cjogxz 3655 12 percutaneous percutaneous JJ cord-015369-72cjogxz 3655 13 approach approach NN cord-015369-72cjogxz 3655 14 under under IN cord-015369-72cjogxz 3655 15 local local JJ cord-015369-72cjogxz 3655 16 anesthesia anesthesia NN cord-015369-72cjogxz 3655 17 and and CC cord-015369-72cjogxz 3655 18 analgesic analgesic JJ cord-015369-72cjogxz 3655 19 sedation sedation NN cord-015369-72cjogxz 3655 20 without without IN cord-015369-72cjogxz 3655 21 surgical surgical JJ cord-015369-72cjogxz 3655 22 cut cut NN cord-015369-72cjogxz 3655 23 - - HYPH cord-015369-72cjogxz 3655 24 down down RP cord-015369-72cjogxz 3655 25 and and CC cord-015369-72cjogxz 3655 26 hemodynamic hemodynamic JJ cord-015369-72cjogxz 3655 27 support support NN cord-015369-72cjogxz 3655 28 . . . cord-015369-72cjogxz 3656 1 After after IN cord-015369-72cjogxz 3656 2 balloon balloon NN cord-015369-72cjogxz 3656 3 valvuloplasty valvuloplasty NN cord-015369-72cjogxz 3656 4 , , , cord-015369-72cjogxz 3656 5 the the DT cord-015369-72cjogxz 3656 6 self self NN cord-015369-72cjogxz 3656 7 - - HYPH cord-015369-72cjogxz 3656 8 expanding expand VBG cord-015369-72cjogxz 3656 9 CoreValve CoreValve NNP cord-015369-72cjogxz 3656 10 prosthesis prosthesis NN cord-015369-72cjogxz 3656 11 ( ( -LRB- cord-015369-72cjogxz 3656 12 diameter diameter NN cord-015369-72cjogxz 3656 13 26 26 CD cord-015369-72cjogxz 3656 14 mm mm NNS cord-015369-72cjogxz 3656 15 , , , cord-015369-72cjogxz 3656 16 n n NNP cord-015369-72cjogxz 3656 17 ¼ ¼ NNP cord-015369-72cjogxz 3656 18 31 31 CD cord-015369-72cjogxz 3656 19 ; ; : cord-015369-72cjogxz 3656 20 29 29 CD cord-015369-72cjogxz 3656 21 mm mm NNP cord-015369-72cjogxz 3656 22 , , , cord-015369-72cjogxz 3656 23 n n NNP cord-015369-72cjogxz 3656 24 ¼ ¼ NNP cord-015369-72cjogxz 3656 25 21 21 CD cord-015369-72cjogxz 3656 26 ) ) -RRB- cord-015369-72cjogxz 3656 27 was be VBD cord-015369-72cjogxz 3656 28 implanted implant VBN cord-015369-72cjogxz 3656 29 using use VBG cord-015369-72cjogxz 3656 30 the the DT cord-015369-72cjogxz 3656 31 current current JJ cord-015369-72cjogxz 3656 32 18 18 CD cord-015369-72cjogxz 3656 33 French french JJ cord-015369-72cjogxz 3656 34 delivery delivery NN cord-015369-72cjogxz 3656 35 catheter catheter NN cord-015369-72cjogxz 3656 36 system system NN cord-015369-72cjogxz 3656 37 . . . cord-015369-72cjogxz 3657 1 Results result NNS cord-015369-72cjogxz 3657 2 . . . cord-015369-72cjogxz 3658 1 Acute acute JJ cord-015369-72cjogxz 3658 2 procedural procedural JJ cord-015369-72cjogxz 3658 3 success success NN cord-015369-72cjogxz 3658 4 rate rate NN cord-015369-72cjogxz 3658 5 was be VBD cord-015369-72cjogxz 3658 6 98 98 CD cord-015369-72cjogxz 3658 7 % % NN cord-015369-72cjogxz 3658 8 . . . cord-015369-72cjogxz 3659 1 Device device NN cord-015369-72cjogxz 3659 2 implantation implantation NN cord-015369-72cjogxz 3659 3 resulted result VBD cord-015369-72cjogxz 3659 4 in in IN cord-015369-72cjogxz 3659 5 a a DT cord-015369-72cjogxz 3659 6 significant significant JJ cord-015369-72cjogxz 3659 7 increase increase NN cord-015369-72cjogxz 3659 8 of of IN cord-015369-72cjogxz 3659 9 calculated calculate VBN cord-015369-72cjogxz 3659 10 aortic aortic JJ cord-015369-72cjogxz 3659 11 valve valve NN cord-015369-72cjogxz 3659 12 area area NN cord-015369-72cjogxz 3659 13 ( ( -LRB- cord-015369-72cjogxz 3659 14 0.5 0.5 CD cord-015369-72cjogxz 3659 15 AE AE NNP cord-015369-72cjogxz 3659 16 0.1 0.1 CD cord-015369-72cjogxz 3659 17 vs. vs. NN cord-015369-72cjogxz 3659 18 1.4 1.4 CD cord-015369-72cjogxz 3659 19 AE AE NNP cord-015369-72cjogxz 3659 20 0.2 0.2 CD cord-015369-72cjogxz 3659 21 cm cm NN cord-015369-72cjogxz 3659 22 2 2 CD cord-015369-72cjogxz 3659 23 , , , cord-015369-72cjogxz 3659 24 p p NN cord-015369-72cjogxz 3659 25 < < XX cord-015369-72cjogxz 3659 26 0.0001 0.0001 CD cord-015369-72cjogxz 3659 27 ) ) -RRB- cord-015369-72cjogxz 3659 28 . . . cord-015369-72cjogxz 3660 1 Postprocedural Postprocedural NNP cord-015369-72cjogxz 3660 2 aortic aortic JJ cord-015369-72cjogxz 3660 3 regurgitation regurgitation NN cord-015369-72cjogxz 3660 4 was be VBD cord-015369-72cjogxz 3660 5 trivial trivial JJ cord-015369-72cjogxz 3660 6 or or CC cord-015369-72cjogxz 3660 7 mild mild JJ cord-015369-72cjogxz 3660 8 in in IN cord-015369-72cjogxz 3660 9 46 46 CD cord-015369-72cjogxz 3660 10 patients patient NNS cord-015369-72cjogxz 3660 11 and and CC cord-015369-72cjogxz 3660 12 moderate moderate JJ cord-015369-72cjogxz 3660 13 in in IN cord-015369-72cjogxz 3660 14 seven seven CD cord-015369-72cjogxz 3660 15 patients patient NNS cord-015369-72cjogxz 3660 16 . . . cord-015369-72cjogxz 3661 1 Permanent permanent JJ cord-015369-72cjogxz 3661 2 pacemaker pacemaker NN cord-015369-72cjogxz 3661 3 implantation implantation NN cord-015369-72cjogxz 3661 4 was be VBD cord-015369-72cjogxz 3661 5 necessary necessary JJ cord-015369-72cjogxz 3661 6 in in IN cord-015369-72cjogxz 3661 7 four four CD cord-015369-72cjogxz 3661 8 patients patient NNS cord-015369-72cjogxz 3661 9 due due JJ cord-015369-72cjogxz 3661 10 to to TO cord-015369-72cjogxz 3661 11 complete complete VB cord-015369-72cjogxz 3661 12 atrioventricular atrioventricular JJ cord-015369-72cjogxz 3661 13 block block NN cord-015369-72cjogxz 3661 14 . . . cord-015369-72cjogxz 3662 1 Major major JJ cord-015369-72cjogxz 3662 2 complications complication NNS cord-015369-72cjogxz 3662 3 were be VBD cord-015369-72cjogxz 3662 4 myocardial myocardial JJ cord-015369-72cjogxz 3662 5 infarction infarction NN cord-015369-72cjogxz 3662 6 ( ( -LRB- cord-015369-72cjogxz 3662 7 n n NN cord-015369-72cjogxz 3662 8 ¼ ¼ NNP cord-015369-72cjogxz 3662 9 1 1 CD cord-015369-72cjogxz 3662 10 ) ) -RRB- cord-015369-72cjogxz 3662 11 , , , cord-015369-72cjogxz 3662 12 stroke stroke NNP cord-015369-72cjogxz 3662 13 ( ( -LRB- cord-015369-72cjogxz 3662 14 n n NN cord-015369-72cjogxz 3662 15 ¼ ¼ NNP cord-015369-72cjogxz 3662 16 2 2 CD cord-015369-72cjogxz 3662 17 ) ) -RRB- cord-015369-72cjogxz 3662 18 and and CC cord-015369-72cjogxz 3662 19 pericardial pericardial JJ cord-015369-72cjogxz 3662 20 tamponade tamponade NN cord-015369-72cjogxz 3662 21 ( ( -LRB- cord-015369-72cjogxz 3662 22 n n NNP cord-015369-72cjogxz 3662 23 ¼ ¼ NNP cord-015369-72cjogxz 3662 24 2 2 CD cord-015369-72cjogxz 3662 25 ) ) -RRB- cord-015369-72cjogxz 3662 26 . . . cord-015369-72cjogxz 3663 1 Actually actually RB cord-015369-72cjogxz 3663 2 , , , cord-015369-72cjogxz 3663 3 allcause allcause NN cord-015369-72cjogxz 3663 4 mortality mortality NN cord-015369-72cjogxz 3663 5 rate rate NN cord-015369-72cjogxz 3663 6 is be VBZ cord-015369-72cjogxz 3663 7 11.3 11.3 CD cord-015369-72cjogxz 3663 8 % % NN cord-015369-72cjogxz 3663 9 at at IN cord-015369-72cjogxz 3663 10 30 30 CD cord-015369-72cjogxz 3663 11 days day NNS cord-015369-72cjogxz 3663 12 and and CC cord-015369-72cjogxz 3663 13 22.6 22.6 CD cord-015369-72cjogxz 3663 14 % % NN cord-015369-72cjogxz 3663 15 after after IN cord-015369-72cjogxz 3663 16 one one CD cord-015369-72cjogxz 3663 17 - - HYPH cord-015369-72cjogxz 3663 18 year year NN cord-015369-72cjogxz 3663 19 follow follow NN cord-015369-72cjogxz 3663 20 - - HYPH cord-015369-72cjogxz 3663 21 up up NN cord-015369-72cjogxz 3663 22 . . . cord-015369-72cjogxz 3664 1 Conclusions conclusion NNS cord-015369-72cjogxz 3664 2 . . . cord-015369-72cjogxz 3665 1 PAVR PAVR NNP cord-015369-72cjogxz 3665 2 with with IN cord-015369-72cjogxz 3665 3 the the DT cord-015369-72cjogxz 3665 4 self self NN cord-015369-72cjogxz 3665 5 - - HYPH cord-015369-72cjogxz 3665 6 expanding expand VBG cord-015369-72cjogxz 3665 7 CoreValve CoreValve NNP cord-015369-72cjogxz 3665 8 bioprosthesis bioprosthesis NNP cord-015369-72cjogxz 3665 9 is be VBZ cord-015369-72cjogxz 3665 10 an an DT cord-015369-72cjogxz 3665 11 emerging emerge VBG cord-015369-72cjogxz 3665 12 alternative alternative JJ cord-015369-72cjogxz 3665 13 treatment treatment NN cord-015369-72cjogxz 3665 14 for for IN cord-015369-72cjogxz 3665 15 high high JJ cord-015369-72cjogxz 3665 16 - - HYPH cord-015369-72cjogxz 3665 17 risk risk NN cord-015369-72cjogxz 3665 18 patients patient NNS cord-015369-72cjogxz 3665 19 with with IN cord-015369-72cjogxz 3665 20 symptomatic symptomatic JJ cord-015369-72cjogxz 3665 21 severe severe JJ cord-015369-72cjogxz 3665 22 AS as NN cord-015369-72cjogxz 3665 23 . . . cord-015369-72cjogxz 3666 1 Complication complication NN cord-015369-72cjogxz 3666 2 rate rate NN cord-015369-72cjogxz 3666 3 is be VBZ cord-015369-72cjogxz 3666 4 acceptable acceptable JJ cord-015369-72cjogxz 3666 5 and and CC cord-015369-72cjogxz 3666 6 mortality mortality NN cord-015369-72cjogxz 3666 7 rate rate NN cord-015369-72cjogxz 3666 8 lower low JJR cord-015369-72cjogxz 3666 9 than than IN cord-015369-72cjogxz 3666 10 predicted predict VBN cord-015369-72cjogxz 3666 11 by by IN cord-015369-72cjogxz 3666 12 risk risk NN cord-015369-72cjogxz 3666 13 calculation calculation NN cord-015369-72cjogxz 3666 14 . . . cord-015369-72cjogxz 3667 1 Results result NNS cord-015369-72cjogxz 3667 2 . . . cord-015369-72cjogxz 3668 1 Median median JJ cord-015369-72cjogxz 3668 2 length length NN cord-015369-72cjogxz 3668 3 of of IN cord-015369-72cjogxz 3668 4 stay stay NN cord-015369-72cjogxz 3668 5 was be VBD cord-015369-72cjogxz 3668 6 12 12 CD cord-015369-72cjogxz 3668 7 days day NNS cord-015369-72cjogxz 3668 8 in in IN cord-015369-72cjogxz 3668 9 conventional conventional JJ cord-015369-72cjogxz 3668 10 open open JJ cord-015369-72cjogxz 3668 11 repair repair NN cord-015369-72cjogxz 3668 12 encomprising encomprise VBG cord-015369-72cjogxz 3668 13 5 5 CD cord-015369-72cjogxz 3668 14 days day NNS cord-015369-72cjogxz 3668 15 on on IN cord-015369-72cjogxz 3668 16 the the DT cord-015369-72cjogxz 3668 17 intensive intensive JJ cord-015369-72cjogxz 3668 18 care care NN cord-015369-72cjogxz 3668 19 unit unit NN cord-015369-72cjogxz 3668 20 . . . cord-015369-72cjogxz 3669 1 Median median JJ cord-015369-72cjogxz 3669 2 length length NN cord-015369-72cjogxz 3669 3 of of IN cord-015369-72cjogxz 3669 4 stay stay NN cord-015369-72cjogxz 3669 5 in in IN cord-015369-72cjogxz 3669 6 stent stent JJ cord-015369-72cjogxz 3669 7 - - HYPH cord-015369-72cjogxz 3669 8 graft graft NN cord-015369-72cjogxz 3669 9 placement placement NN cord-015369-72cjogxz 3669 10 was be VBD cord-015369-72cjogxz 3669 11 5 5 CD cord-015369-72cjogxz 3669 12 days day NNS cord-015369-72cjogxz 3669 13 . . . cord-015369-72cjogxz 3670 1 The the DT cord-015369-72cjogxz 3670 2 day day NN cord-015369-72cjogxz 3670 3 rate rate NN cord-015369-72cjogxz 3670 4 on on IN cord-015369-72cjogxz 3670 5 the the DT cord-015369-72cjogxz 3670 6 normal normal JJ cord-015369-72cjogxz 3670 7 ward ward NN cord-015369-72cjogxz 3670 8 is be VBZ cord-015369-72cjogxz 3670 9 estimated estimate VBN cord-015369-72cjogxz 3670 10 at at IN cord-015369-72cjogxz 3670 11 1.180.00D 1.180.00d CD cord-015369-72cjogxz 3670 12 and and CC cord-015369-72cjogxz 3670 13 the the DT cord-015369-72cjogxz 3670 14 day day NN cord-015369-72cjogxz 3670 15 rate rate NN cord-015369-72cjogxz 3670 16 on on IN cord-015369-72cjogxz 3670 17 the the DT cord-015369-72cjogxz 3670 18 intensive intensive JJ cord-015369-72cjogxz 3670 19 care care NN cord-015369-72cjogxz 3670 20 unit unit NN cord-015369-72cjogxz 3670 21 is be VBZ cord-015369-72cjogxz 3670 22 estimated estimate VBN cord-015369-72cjogxz 3670 23 at at IN cord-015369-72cjogxz 3670 24 3.014.00D 3.014.00d CD cord-015369-72cjogxz 3670 25 . . . cord-015369-72cjogxz 3671 1 Median median JJ cord-015369-72cjogxz 3671 2 number number NN cord-015369-72cjogxz 3671 3 of of IN cord-015369-72cjogxz 3671 4 stent stent NN cord-015369-72cjogxz 3671 5 - - HYPH cord-015369-72cjogxz 3671 6 grafts graft NNS cord-015369-72cjogxz 3671 7 used use VBN cord-015369-72cjogxz 3671 8 was be VBD cord-015369-72cjogxz 3671 9 1.7 1.7 CD cord-015369-72cjogxz 3671 10 . . . cord-015369-72cjogxz 3672 1 Despite despite IN cord-015369-72cjogxz 3672 2 substantial substantial JJ cord-015369-72cjogxz 3672 3 higher high JJR cord-015369-72cjogxz 3672 4 procedural procedural JJ cord-015369-72cjogxz 3672 5 costs cost NNS cord-015369-72cjogxz 3672 6 of of IN cord-015369-72cjogxz 3672 7 stent stent JJ cord-015369-72cjogxz 3672 8 - - HYPH cord-015369-72cjogxz 3672 9 graft graft NN cord-015369-72cjogxz 3672 10 placement placement NN cord-015369-72cjogxz 3672 11 ( ( -LRB- cord-015369-72cjogxz 3672 12 32.320.98D 32.320.98d CD cord-015369-72cjogxz 3672 13 versus versus IN cord-015369-72cjogxz 3672 14 19.534.12D 19.534.12d CD cord-015369-72cjogxz 3672 15 ) ) -RRB- cord-015369-72cjogxz 3672 16 , , , cord-015369-72cjogxz 3672 17 total total JJ cord-015369-72cjogxz 3672 18 cost cost NN cord-015369-72cjogxz 3672 19 performance performance NN cord-015369-72cjogxz 3672 20 was be VBD cord-015369-72cjogxz 3672 21 lower low JJR cord-015369-72cjogxz 3672 22 ( ( -LRB- cord-015369-72cjogxz 3672 23 38.220.98D 38.220.98d CD cord-015369-72cjogxz 3672 24 versus versus IN cord-015369-72cjogxz 3672 25 50.764.12D 50.764.12d CD cord-015369-72cjogxz 3672 26 ) ) -RRB- cord-015369-72cjogxz 3672 27 resulting result VBG cord-015369-72cjogxz 3672 28 in in IN cord-015369-72cjogxz 3672 29 a a DT cord-015369-72cjogxz 3672 30 cost cost NN cord-015369-72cjogxz 3672 31 difference difference NN cord-015369-72cjogxz 3672 32 of of IN cord-015369-72cjogxz 3672 33 12.543.14D 12.543.14d CD cord-015369-72cjogxz 3672 34 . . . cord-015369-72cjogxz 3673 1 As as IN cord-015369-72cjogxz 3673 2 a a DT cord-015369-72cjogxz 3673 3 consequence consequence NN cord-015369-72cjogxz 3673 4 , , , cord-015369-72cjogxz 3673 5 the the DT cord-015369-72cjogxz 3673 6 cost cost NN cord-015369-72cjogxz 3673 7 advantage advantage NN cord-015369-72cjogxz 3673 8 of of IN cord-015369-72cjogxz 3673 9 stent stent JJ cord-015369-72cjogxz 3673 10 - - HYPH cord-015369-72cjogxz 3673 11 graft graft NN cord-015369-72cjogxz 3673 12 placement placement NN cord-015369-72cjogxz 3673 13 turned turn VBD cord-015369-72cjogxz 3673 14 out out RP cord-015369-72cjogxz 3673 15 to to TO cord-015369-72cjogxz 3673 16 be be VB cord-015369-72cjogxz 3673 17 24.7 24.7 CD cord-015369-72cjogxz 3673 18 % % NN cord-015369-72cjogxz 3673 19 . . . cord-015369-72cjogxz 3674 1 Conclusions conclusion NNS cord-015369-72cjogxz 3674 2 . . . cord-015369-72cjogxz 3675 1 Despite despite IN cord-015369-72cjogxz 3675 2 substantially substantially RB cord-015369-72cjogxz 3675 3 higher high JJR cord-015369-72cjogxz 3675 4 procedural procedural JJ cord-015369-72cjogxz 3675 5 costs cost NNS cord-015369-72cjogxz 3675 6 as as IN cord-015369-72cjogxz 3675 7 compared compare VBN cord-015369-72cjogxz 3675 8 to to IN cord-015369-72cjogxz 3675 9 conventional conventional JJ cord-015369-72cjogxz 3675 10 open open JJ cord-015369-72cjogxz 3675 11 repair repair NN cord-015369-72cjogxz 3675 12 of of IN cord-015369-72cjogxz 3675 13 descending descend VBG cord-015369-72cjogxz 3675 14 thoracic thoracic JJ cord-015369-72cjogxz 3675 15 aortic aortic JJ cord-015369-72cjogxz 3675 16 aneurysms aneurysm NNS cord-015369-72cjogxz 3675 17 , , , cord-015369-72cjogxz 3675 18 endovascular endovascular JJ cord-015369-72cjogxz 3675 19 stent stent NN cord-015369-72cjogxz 3675 20 - - HYPH cord-015369-72cjogxz 3675 21 graft graft NN cord-015369-72cjogxz 3675 22 placement placement NN cord-015369-72cjogxz 3675 23 is be VBZ cord-015369-72cjogxz 3675 24 cost cost VBN cord-015369-72cjogxz 3675 25 efficient efficient JJ cord-015369-72cjogxz 3675 26 mainly mainly RB cord-015369-72cjogxz 3675 27 due due IN cord-015369-72cjogxz 3675 28 to to IN cord-015369-72cjogxz 3675 29 the the DT cord-015369-72cjogxz 3675 30 preventable preventable JJ cord-015369-72cjogxz 3675 31 intensive intensive JJ cord-015369-72cjogxz 3675 32 care care NN cord-015369-72cjogxz 3675 33 stay stay NN cord-015369-72cjogxz 3675 34 and and CC cord-015369-72cjogxz 3675 35 the the DT cord-015369-72cjogxz 3675 36 shorter short JJR cord-015369-72cjogxz 3675 37 in in IN cord-015369-72cjogxz 3675 38 - - HYPH cord-015369-72cjogxz 3675 39 hospital hospital NN cord-015369-72cjogxz 3675 40 stay stay NN cord-015369-72cjogxz 3675 41 . . . cord-015369-72cjogxz 3676 1 Background background NN cord-015369-72cjogxz 3676 2 . . . cord-015369-72cjogxz 3677 1 Supra supra NN cord-015369-72cjogxz 3677 2 - - HYPH cord-015369-72cjogxz 3677 3 aortic aortic JJ cord-015369-72cjogxz 3677 4 transpositions transposition NNS cord-015369-72cjogxz 3677 5 followed follow VBN cord-015369-72cjogxz 3677 6 by by IN cord-015369-72cjogxz 3677 7 endovascular endovascular JJ cord-015369-72cjogxz 3677 8 stent stent NN cord-015369-72cjogxz 3677 9 graft graft NN cord-015369-72cjogxz 3677 10 placement placement NN cord-015369-72cjogxz 3677 11 are be VBP cord-015369-72cjogxz 3677 12 now now RB cord-015369-72cjogxz 3677 13 an an DT cord-015369-72cjogxz 3677 14 established establish VBN cord-015369-72cjogxz 3677 15 tool tool NN cord-015369-72cjogxz 3677 16 in in IN cord-015369-72cjogxz 3677 17 the the DT cord-015369-72cjogxz 3677 18 treatment treatment NN cord-015369-72cjogxz 3677 19 of of IN cord-015369-72cjogxz 3677 20 aortic aortic JJ cord-015369-72cjogxz 3677 21 arch arch JJ cord-015369-72cjogxz 3677 22 pathologies pathology NNS cord-015369-72cjogxz 3677 23 . . . cord-015369-72cjogxz 3678 1 Results result NNS cord-015369-72cjogxz 3678 2 remain remain VBP cord-015369-72cjogxz 3678 3 to to TO cord-015369-72cjogxz 3678 4 be be VB cord-015369-72cjogxz 3678 5 determined determine VBN cord-015369-72cjogxz 3678 6 . . . cord-015369-72cjogxz 3679 1 Methods method NNS cord-015369-72cjogxz 3679 2 . . . cord-015369-72cjogxz 3680 1 From from IN cord-015369-72cjogxz 3680 2 1996 1996 CD cord-015369-72cjogxz 3680 3 through through IN cord-015369-72cjogxz 3680 4 2008 2008 CD cord-015369-72cjogxz 3680 5 , , , cord-015369-72cjogxz 3680 6 73 73 CD cord-015369-72cjogxz 3680 7 patients patient NNS cord-015369-72cjogxz 3680 8 ( ( -LRB- cord-015369-72cjogxz 3680 9 median median JJ cord-015369-72cjogxz 3680 10 age age NN cord-015369-72cjogxz 3680 11 , , , cord-015369-72cjogxz 3680 12 71 71 CD cord-015369-72cjogxz 3680 13 years year NNS cord-015369-72cjogxz 3680 14 ) ) -RRB- cord-015369-72cjogxz 3680 15 presented present VBN cord-015369-72cjogxz 3680 16 with with IN cord-015369-72cjogxz 3680 17 aortic aortic JJ cord-015369-72cjogxz 3680 18 arch arch NN cord-015369-72cjogxz 3680 19 pathology pathology NN cord-015369-72cjogxz 3680 20 ( ( -LRB- cord-015369-72cjogxz 3680 21 aneurysms aneurysm NNS cord-015369-72cjogxz 3680 22 , , , cord-015369-72cjogxz 3680 23 n n NN cord-015369-72cjogxz 3680 24 ¼ ¼ NNP cord-015369-72cjogxz 3680 25 42 42 CD cord-015369-72cjogxz 3680 26 ; ; : cord-015369-72cjogxz 3680 27 type type NN cord-015369-72cjogxz 3680 28 B b NN cord-015369-72cjogxz 3680 29 dissections dissection NNS cord-015369-72cjogxz 3680 30 , , , cord-015369-72cjogxz 3680 31 n n CC cord-015369-72cjogxz 3680 32 ¼ ¼ NNP cord-015369-72cjogxz 3680 33 9 9 CD cord-015369-72cjogxz 3680 34 ; ; : cord-015369-72cjogxz 3680 35 penetrating penetrate VBG cord-015369-72cjogxz 3680 36 ulcers ulcer NNS cord-015369-72cjogxz 3680 37 , , , cord-015369-72cjogxz 3680 38 n n NN cord-015369-72cjogxz 3680 39 ¼ ¼ NNP cord-015369-72cjogxz 3680 40 17 17 CD cord-015369-72cjogxz 3680 41 ; ; , cord-015369-72cjogxz 3680 42 traumatic traumatic JJ cord-015369-72cjogxz 3680 43 lesions lesion NNS cord-015369-72cjogxz 3680 44 , , , cord-015369-72cjogxz 3680 45 n n NN cord-015369-72cjogxz 3680 46 ¼ ¼ NNP cord-015369-72cjogxz 3680 47 2 2 CD cord-015369-72cjogxz 3680 48 ; ; , cord-015369-72cjogxz 3680 49 aneurysms aneurysm NNS cord-015369-72cjogxz 3680 50 based base VBN cord-015369-72cjogxz 3680 51 on on IN cord-015369-72cjogxz 3680 52 prior prior JJ cord-015369-72cjogxz 3680 53 surgery surgery NN cord-015369-72cjogxz 3680 54 for for IN cord-015369-72cjogxz 3680 55 aortic aortic JJ cord-015369-72cjogxz 3680 56 coarctation coarctation NN cord-015369-72cjogxz 3680 57 , , , cord-015369-72cjogxz 3680 58 n n NN cord-015369-72cjogxz 3680 59 ¼ ¼ NNP cord-015369-72cjogxz 3680 60 3 3 CD cord-015369-72cjogxz 3680 61 ) ) -RRB- cord-015369-72cjogxz 3680 62 . . . cord-015369-72cjogxz 3681 1 Strategy strategy NN cord-015369-72cjogxz 3681 2 for for IN cord-015369-72cjogxz 3681 3 distal distal JJ cord-015369-72cjogxz 3681 4 arch arch JJ cord-015369-72cjogxz 3681 5 disease disease NN cord-015369-72cjogxz 3681 6 was be VBD cord-015369-72cjogxz 3681 7 subclavian subclavian JJ cord-015369-72cjogxz 3681 8 - - HYPH cord-015369-72cjogxz 3681 9 to to IN cord-015369-72cjogxz 3681 10 - - HYPH cord-015369-72cjogxz 3681 11 carotid carotid NN cord-015369-72cjogxz 3681 12 transposition transposition NN cord-015369-72cjogxz 3681 13 ( ( -LRB- cord-015369-72cjogxz 3681 14 n n NN cord-015369-72cjogxz 3681 15 ¼ ¼ NNP cord-015369-72cjogxz 3681 16 24 24 CD cord-015369-72cjogxz 3681 17 ) ) -RRB- cord-015369-72cjogxz 3681 18 or or CC cord-015369-72cjogxz 3681 19 autologous autologous JJ cord-015369-72cjogxz 3681 20 double double JJ cord-015369-72cjogxz 3681 21 - - HYPH cord-015369-72cjogxz 3681 22 vessel vessel NN cord-015369-72cjogxz 3681 23 transposition transposition NN cord-015369-72cjogxz 3681 24 through through IN cord-015369-72cjogxz 3681 25 upper upper JJ cord-015369-72cjogxz 3681 26 hemisternotomy hemisternotomy NNP cord-015369-72cjogxz 3681 27 ( ( -LRB- cord-015369-72cjogxz 3681 28 n n NN cord-015369-72cjogxz 3681 29 ¼ ¼ NNP cord-015369-72cjogxz 3681 30 36 36 CD cord-015369-72cjogxz 3681 31 ) ) -RRB- cord-015369-72cjogxz 3681 32 . . . cord-015369-72cjogxz 3682 1 For for IN cord-015369-72cjogxz 3682 2 entire entire JJ cord-015369-72cjogxz 3682 3 arch arch JJ cord-015369-72cjogxz 3682 4 disease disease NN cord-015369-72cjogxz 3682 5 , , , cord-015369-72cjogxz 3682 6 total total JJ cord-015369-72cjogxz 3682 7 supra supra JJ cord-015369-72cjogxz 3682 8 - - HYPH cord-015369-72cjogxz 3682 9 aortic aortic JJ cord-015369-72cjogxz 3682 10 rerouting rerouting NN cord-015369-72cjogxz 3682 11 with with IN cord-015369-72cjogxz 3682 12 a a DT cord-015369-72cjogxz 3682 13 reversed reverse VBN cord-015369-72cjogxz 3682 14 bifurcated bifurcated JJ cord-015369-72cjogxz 3682 15 prosthesis prosthesis NN cord-015369-72cjogxz 3682 16 was be VBD cord-015369-72cjogxz 3682 17 applied apply VBN cord-015369-72cjogxz 3682 18 ( ( -LRB- cord-015369-72cjogxz 3682 19 n n NNP cord-015369-72cjogxz 3682 20 ¼ ¼ NNP cord-015369-72cjogxz 3682 21 13 13 CD cord-015369-72cjogxz 3682 22 ) ) -RRB- cord-015369-72cjogxz 3682 23 . . . cord-015369-72cjogxz 3683 1 Endovascular Endovascular NNP cord-015369-72cjogxz 3683 2 stent stent NN cord-015369-72cjogxz 3683 3 graft graft NN cord-015369-72cjogxz 3683 4 placement placement NN cord-015369-72cjogxz 3683 5 was be VBD cord-015369-72cjogxz 3683 6 performed perform VBN cord-015369-72cjogxz 3683 7 metachronously metachronously RB cord-015369-72cjogxz 3683 8 . . . cord-015369-72cjogxz 3684 1 Results result NNS cord-015369-72cjogxz 3684 2 . . . cord-015369-72cjogxz 3685 1 In in IN cord-015369-72cjogxz 3685 2 - - HYPH cord-015369-72cjogxz 3685 3 hospital hospital NN cord-015369-72cjogxz 3685 4 mortality mortality NN cord-015369-72cjogxz 3685 5 was be VBD cord-015369-72cjogxz 3685 6 6.8 6.8 CD cord-015369-72cjogxz 3685 7 % % NN cord-015369-72cjogxz 3685 8 ( ( -LRB- cord-015369-72cjogxz 3685 9 n n NN cord-015369-72cjogxz 3685 10 ¼ ¼ NNP cord-015369-72cjogxz 3685 11 5 5 CD cord-015369-72cjogxz 3685 12 ) ) -RRB- cord-015369-72cjogxz 3685 13 . . . cord-015369-72cjogxz 3686 1 Persistent persistent JJ cord-015369-72cjogxz 3686 2 early early JJ cord-015369-72cjogxz 3686 3 type type NN cord-015369-72cjogxz 3686 4 I -PRON- PRP cord-015369-72cjogxz 3686 5 and and CC cord-015369-72cjogxz 3686 6 III iii CD cord-015369-72cjogxz 3686 7 endoleak endoleak NN cord-015369-72cjogxz 3686 8 rate rate NN cord-015369-72cjogxz 3686 9 was be VBD cord-015369-72cjogxz 3686 10 9.6 9.6 CD cord-015369-72cjogxz 3686 11 % % NN cord-015369-72cjogxz 3686 12 . . . cord-015369-72cjogxz 3687 1 Persistent persistent JJ cord-015369-72cjogxz 3687 2 late late JJ cord-015369-72cjogxz 3687 3 type type NN cord-015369-72cjogxz 3687 4 I -PRON- PRP cord-015369-72cjogxz 3687 5 and and CC cord-015369-72cjogxz 3687 6 III iii CD cord-015369-72cjogxz 3687 7 endoleak endoleak NN cord-015369-72cjogxz 3687 8 rate rate NN cord-015369-72cjogxz 3687 9 was be VBD cord-015369-72cjogxz 3687 10 5.5 5.5 CD cord-015369-72cjogxz 3687 11 % % NN cord-015369-72cjogxz 3687 12 . . . cord-015369-72cjogxz 3688 1 Overall overall JJ cord-015369-72cjogxz 3688 2 actuarial actuarial JJ cord-015369-72cjogxz 3688 3 survival survival NN cord-015369-72cjogxz 3688 4 was be VBD cord-015369-72cjogxz 3688 5 90 90 CD cord-015369-72cjogxz 3688 6 % % NN cord-015369-72cjogxz 3688 7 , , , cord-015369-72cjogxz 3688 8 86 86 CD cord-015369-72cjogxz 3688 9 % % NN cord-015369-72cjogxz 3688 10 , , , cord-015369-72cjogxz 3688 11 and and CC cord-015369-72cjogxz 3688 12 72 72 CD cord-015369-72cjogxz 3688 13 % % NN cord-015369-72cjogxz 3688 14 at at IN cord-015369-72cjogxz 3688 15 1 1 CD cord-015369-72cjogxz 3688 16 , , , cord-015369-72cjogxz 3688 17 3 3 CD cord-015369-72cjogxz 3688 18 , , , cord-015369-72cjogxz 3688 19 and and CC cord-015369-72cjogxz 3688 20 5 5 CD cord-015369-72cjogxz 3688 21 years year NNS cord-015369-72cjogxz 3688 22 . . . cord-015369-72cjogxz 3689 1 Mean mean JJ cord-015369-72cjogxz 3689 2 follow follow NN cord-015369-72cjogxz 3689 3 - - HYPH cord-015369-72cjogxz 3689 4 up up NN cord-015369-72cjogxz 3689 5 is be VBZ cord-015369-72cjogxz 3689 6 37 37 CD cord-015369-72cjogxz 3689 7 months month NNS cord-015369-72cjogxz 3689 8 ( ( -LRB- cord-015369-72cjogxz 3689 9 range range NN cord-015369-72cjogxz 3689 10 , , , cord-015369-72cjogxz 3689 11 1 1 CD cord-015369-72cjogxz 3689 12 to to IN cord-015369-72cjogxz 3689 13 120 120 CD cord-015369-72cjogxz 3689 14 ) ) -RRB- cord-015369-72cjogxz 3689 15 . . . cord-015369-72cjogxz 3690 1 Early early JJ cord-015369-72cjogxz 3690 2 and and CC cord-015369-72cjogxz 3690 3 late late JJ cord-015369-72cjogxz 3690 4 endoleak endoleak NN cord-015369-72cjogxz 3690 5 formation formation NN cord-015369-72cjogxz 3690 6 was be VBD cord-015369-72cjogxz 3690 7 independently independently RB cord-015369-72cjogxz 3690 8 predicted predict VBN cord-015369-72cjogxz 3690 9 by by IN cord-015369-72cjogxz 3690 10 the the DT cord-015369-72cjogxz 3690 11 number number NN cord-015369-72cjogxz 3690 12 of of IN cord-015369-72cjogxz 3690 13 prostheses prosthesis NNS cord-015369-72cjogxz 3690 14 . . . cord-015369-72cjogxz 3691 1 Survival survival NN cord-015369-72cjogxz 3691 2 was be VBD cord-015369-72cjogxz 3691 3 independently independently RB cord-015369-72cjogxz 3691 4 predicted predict VBN cord-015369-72cjogxz 3691 5 by by IN cord-015369-72cjogxz 3691 6 higher high JJR cord-015369-72cjogxz 3691 7 logistic logistic JJ cord-015369-72cjogxz 3691 8 EuroSCORE EuroSCORE NNP cord-015369-72cjogxz 3691 9 levels level NNS cord-015369-72cjogxz 3691 10 . . . cord-015369-72cjogxz 3692 1 Conclusions conclusion NNS cord-015369-72cjogxz 3692 2 . . . cord-015369-72cjogxz 3693 1 Results result NNS cord-015369-72cjogxz 3693 2 after after IN cord-015369-72cjogxz 3693 3 supra supra JJ cord-015369-72cjogxz 3693 4 - - HYPH cord-015369-72cjogxz 3693 5 aortic aortic JJ cord-015369-72cjogxz 3693 6 transpositions transposition NNS cord-015369-72cjogxz 3693 7 followed follow VBN cord-015369-72cjogxz 3693 8 by by IN cord-015369-72cjogxz 3693 9 stent stent NN cord-015369-72cjogxz 3693 10 graft graft NN cord-015369-72cjogxz 3693 11 placement placement NN cord-015369-72cjogxz 3693 12 for for IN cord-015369-72cjogxz 3693 13 the the DT cord-015369-72cjogxz 3693 14 treatment treatment NN cord-015369-72cjogxz 3693 15 of of IN cord-015369-72cjogxz 3693 16 aortic aortic JJ cord-015369-72cjogxz 3693 17 arch arch JJ cord-015369-72cjogxz 3693 18 pathologies pathology NNS cord-015369-72cjogxz 3693 19 are be VBP cord-015369-72cjogxz 3693 20 promising promising JJ cord-015369-72cjogxz 3693 21 . . . cord-015369-72cjogxz 3694 1 Endoleak Endoleak NNP cord-015369-72cjogxz 3694 2 formation formation NN cord-015369-72cjogxz 3694 3 is be VBZ cord-015369-72cjogxz 3694 4 directly directly RB cord-015369-72cjogxz 3694 5 related relate VBN cord-015369-72cjogxz 3694 6 to to IN cord-015369-72cjogxz 3694 7 the the DT cord-015369-72cjogxz 3694 8 number number NN cord-015369-72cjogxz 3694 9 of of IN cord-015369-72cjogxz 3694 10 prostheses prosthesis NNS cord-015369-72cjogxz 3694 11 and and CC cord-015369-72cjogxz 3694 12 may may MD cord-015369-72cjogxz 3694 13 be be VB cord-015369-72cjogxz 3694 14 reduced reduce VBN cord-015369-72cjogxz 3694 15 by by IN cord-015369-72cjogxz 3694 16 longer long JJR cord-015369-72cjogxz 3694 17 devices device NNS cord-015369-72cjogxz 3694 18 . . . cord-015369-72cjogxz 3695 1 Each each DT cord-015369-72cjogxz 3695 2 type type NN cord-015369-72cjogxz 3695 3 of of IN cord-015369-72cjogxz 3695 4 arch arch JJ cord-015369-72cjogxz 3695 5 rerouting rerouting NN cord-015369-72cjogxz 3695 6 has have VBZ cord-015369-72cjogxz 3695 7 turned turn VBN cord-015369-72cjogxz 3695 8 out out RP cord-015369-72cjogxz 3695 9 to to TO cord-015369-72cjogxz 3695 10 be be VB cord-015369-72cjogxz 3695 11 effective effective JJ cord-015369-72cjogxz 3695 12 . . . cord-015369-72cjogxz 3696 1 Extended extended JJ cord-015369-72cjogxz 3696 2 application application NN cord-015369-72cjogxz 3696 3 of of IN cord-015369-72cjogxz 3696 4 these these DT cord-015369-72cjogxz 3696 5 combined combine VBN cord-015369-72cjogxz 3696 6 treatment treatment NN cord-015369-72cjogxz 3696 7 strategies strategy NNS cord-015369-72cjogxz 3696 8 substantially substantially RB cord-015369-72cjogxz 3696 9 augments augment VBZ cord-015369-72cjogxz 3696 10 the the DT cord-015369-72cjogxz 3696 11 therapeutic therapeutic JJ cord-015369-72cjogxz 3696 12 options option NNS cord-015369-72cjogxz 3696 13 . . . cord-015369-72cjogxz 3697 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 3697 2 . . . cord-015369-72cjogxz 3698 1 I -PRON- PRP cord-015369-72cjogxz 3698 2 m be VBP cord-015369-72cjogxz 3698 3 Rahmen Rahmen NNP cord-015369-72cjogxz 3698 4 einer einer NNP cord-015369-72cjogxz 3698 5 Aortendissektion Aortendissektion NNP cord-015369-72cjogxz 3699 1 Typ Typ NNP cord-015369-72cjogxz 3699 2 A a DT cord-015369-72cjogxz 3699 3 wird wird JJ cord-015369-72cjogxz 3699 4 bei bei NNP cord-015369-72cjogxz 3699 5 herkömmlichen herkömmlichen NNP cord-015369-72cjogxz 3700 1 Operationsmethoden Operationsmethoden NNP cord-015369-72cjogxz 3700 2 die die VBP cord-015369-72cjogxz 3701 1 Aorta Aorta NNP cord-015369-72cjogxz 3701 2 aszendens aszenden NNS cord-015369-72cjogxz 3701 3 und und IN cord-015369-72cjogxz 3701 4 Teile Teile NNP cord-015369-72cjogxz 3701 5 des des FW cord-015369-72cjogxz 3701 6 Aortenbogens Aortenbogens NNP cord-015369-72cjogxz 3701 7 ersetzt ersetzt VBN cord-015369-72cjogxz 3701 8 , , , cord-015369-72cjogxz 3701 9 die die VBP cord-015369-72cjogxz 3701 10 absteigende absteigende NNP cord-015369-72cjogxz 3701 11 Aorta Aorta NNP cord-015369-72cjogxz 3701 12 bleibt bleibt NNP cord-015369-72cjogxz 3701 13 jedoch jedoch NNP cord-015369-72cjogxz 3701 14 unbehandelt unbehandelt NNP cord-015369-72cjogxz 3701 15 . . . cord-015369-72cjogxz 3702 1 Das Das NNP cord-015369-72cjogxz 3702 2 falsche falsche JJ cord-015369-72cjogxz 3702 3 Lumen Lumen NNP cord-015369-72cjogxz 3702 4 der der NN cord-015369-72cjogxz 3702 5 thorakalen thorakalen NNP cord-015369-72cjogxz 3703 1 Aorta Aorta NNP cord-015369-72cjogxz 3703 2 bleibt bleibt NNP cord-015369-72cjogxz 3703 3 in in IN cord-015369-72cjogxz 3703 4 bis bis NNP cord-015369-72cjogxz 3703 5 zu zu NNP cord-015369-72cjogxz 3703 6 70 70 CD cord-015369-72cjogxz 3703 7 % % NN cord-015369-72cjogxz 3703 8 der der NNP cord-015369-72cjogxz 3703 9 Fälle Fälle NNP cord-015369-72cjogxz 3703 10 perfundiert perfundiert NN cord-015369-72cjogxz 3703 11 . . . cord-015369-72cjogxz 3704 1 Wir Wir NNP cord-015369-72cjogxz 3704 2 berichten berichten NNP cord-015369-72cjogxz 3705 1 über über NNP cord-015369-72cjogxz 3705 2 ein ein NNP cord-015369-72cjogxz 3705 3 kombiniertes kombiniertes NNP cord-015369-72cjogxz 3706 1 chirurgisches chirurgisches NNP cord-015369-72cjogxz 3706 2 und und IN cord-015369-72cjogxz 3707 1 endovaskuläres endovaskuläres NNP cord-015369-72cjogxz 3707 2 Verfahren Verfahren NNP cord-015369-72cjogxz 3708 1 für für NNS cord-015369-72cjogxz 3708 2 die die VBP cord-015369-72cjogxz 3708 3 Behandlung Behandlung NNP cord-015369-72cjogxz 3708 4 komplexer komplexer NNP cord-015369-72cjogxz 3709 1 Typ Typ NNP cord-015369-72cjogxz 3709 2 A A NNP cord-015369-72cjogxz 3710 1 Dissektionen Dissektionen NNP cord-015369-72cjogxz 3710 2 unter unter NNP cord-015369-72cjogxz 3710 3 Verwendung Verwendung NNP cord-015369-72cjogxz 3710 4 einer einer NNP cord-015369-72cjogxz 3710 5 Hybridprothese Hybridprothese NNP cord-015369-72cjogxz 3710 6 . . . cord-015369-72cjogxz 3711 1 Methodik Methodik NNP cord-015369-72cjogxz 3711 2 . . . cord-015369-72cjogxz 3712 1 Zwischen Zwischen NNP cord-015369-72cjogxz 3712 2 08/05 08/05 CD cord-015369-72cjogxz 3712 3 und und IN cord-015369-72cjogxz 3712 4 12/08 12/08 CD cord-015369-72cjogxz 3712 5 wurde wurde NN cord-015369-72cjogxz 3712 6 6 6 CD cord-015369-72cjogxz 3713 1 Patienten Patienten NNP cord-015369-72cjogxz 3713 2 ( ( -LRB- cord-015369-72cjogxz 3713 3 44,5 44,5 CD cord-015369-72cjogxz 3713 4 AE AE NNP cord-015369-72cjogxz 3713 5 15,5 15,5 CD cord-015369-72cjogxz 3713 6 Jahre Jahre NNP cord-015369-72cjogxz 3713 7 ; ; : cord-015369-72cjogxz 3713 8 5 5 CD cord-015369-72cjogxz 3713 9 männlich männlich NNP cord-015369-72cjogxz 3713 10 , , , cord-015369-72cjogxz 3713 11 1 1 CD cord-015369-72cjogxz 3713 12 weiblich weiblich NNP cord-015369-72cjogxz 3713 13 ) ) -RRB- cord-015369-72cjogxz 3713 14 mit mit NNP cord-015369-72cjogxz 3713 15 Aortendissektion Aortendissektion NNP cord-015369-72cjogxz 3713 16 Typ Typ NNP cord-015369-72cjogxz 3713 17 A A NNP cord-015369-72cjogxz 3713 18 ( ( -LRB- cord-015369-72cjogxz 3713 19 3 3 NNP cord-015369-72cjogxz 3713 20 akut akut NNP cord-015369-72cjogxz 3713 21 , , , cord-015369-72cjogxz 3713 22 3 3 CD cord-015369-72cjogxz 3713 23 chronisch chronisch NN cord-015369-72cjogxz 3713 24 ) ) -RRB- cord-015369-72cjogxz 3714 1 die die VB cord-015369-72cjogxz 3714 2 E E NNP cord-015369-72cjogxz 3714 3 - - HYPH cord-015369-72cjogxz 3714 4 Vita Vita NNP cord-015369-72cjogxz 3714 5 Open Open NNP cord-015369-72cjogxz 3714 6 Endoluminal Endoluminal NNP cord-015369-72cjogxz 3714 7 Stentgraftprothese Stentgraftprothese NNP cord-015369-72cjogxz 3715 1 i -PRON- PRP cord-015369-72cjogxz 3715 2 m be VBP cord-015369-72cjogxz 3715 3 Kreislaufstillstand Kreislaufstillstand NNP cord-015369-72cjogxz 3715 4 in in IN cord-015369-72cjogxz 3715 5 moderater moderater NNP cord-015369-72cjogxz 3715 6 Hypothermie Hypothermie NNP cord-015369-72cjogxz 3715 7 mit mit NNP cord-015369-72cjogxz 3715 8 selektiver selektiver NNP cord-015369-72cjogxz 3715 9 antegrader antegrader NNP cord-015369-72cjogxz 3715 10 Hirnperfusion Hirnperfusion NNP cord-015369-72cjogxz 3715 11 implantiert implantiert NN cord-015369-72cjogxz 3715 12 . . . cord-015369-72cjogxz 3716 1 Der Der NNP cord-015369-72cjogxz 3716 2 gestentete gestentete NNP cord-015369-72cjogxz 3717 1 Teil Teil NNP cord-015369-72cjogxz 3717 2 der der NNP cord-015369-72cjogxz 3718 1 Prothese Prothese NNP cord-015369-72cjogxz 3718 2 wird wird NNP cord-015369-72cjogxz 3718 3 über über NNP cord-015369-72cjogxz 3718 4 den den NN cord-015369-72cjogxz 3718 5 eröffneten eröffneten NNP cord-015369-72cjogxz 3718 6 Aortenbogen Aortenbogen NNP cord-015369-72cjogxz 3718 7 in in IN cord-015369-72cjogxz 3718 8 die die NN cord-015369-72cjogxz 3719 1 Aorta Aorta NNP cord-015369-72cjogxz 3719 2 deszendens deszenden VBZ cord-015369-72cjogxz 3719 3 vorgeschoben vorgeschoben NN cord-015369-72cjogxz 3719 4 , , , cord-015369-72cjogxz 3720 1 anschließend anschließend NNP cord-015369-72cjogxz 3720 2 wird wird NNP cord-015369-72cjogxz 3720 3 mit mit NNP cord-015369-72cjogxz 3720 4 der der NNP cord-015369-72cjogxz 3720 5 Dacron Dacron NNP cord-015369-72cjogxz 3720 6 Hälfte Hälfte NNP cord-015369-72cjogxz 3720 7 der der NNP cord-015369-72cjogxz 3720 8 Prothese Prothese NNP cord-015369-72cjogxz 3720 9 der der NNP cord-015369-72cjogxz 3720 10 Aortenbogen Aortenbogen NNP cord-015369-72cjogxz 3721 1 und und NNP cord-015369-72cjogxz 3721 2 die die VB cord-015369-72cjogxz 3721 3 distale distale NNP cord-015369-72cjogxz 3721 4 Aorta Aorta NNP cord-015369-72cjogxz 3721 5 aszendens aszenden NNS cord-015369-72cjogxz 3721 6 ersetzt ersetzt VBN cord-015369-72cjogxz 3721 7 . . . cord-015369-72cjogxz 3722 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 3722 2 . . . cord-015369-72cjogxz 3723 1 Alle Alle NNP cord-015369-72cjogxz 3723 2 Patienten Patienten NNP cord-015369-72cjogxz 3723 3 überlebten überlebten NN cord-015369-72cjogxz 3723 4 den den NNP cord-015369-72cjogxz 3723 5 Eingriff Eingriff NNP cord-015369-72cjogxz 3723 6 ohne ohne NNP cord-015369-72cjogxz 3723 7 neurologischem neurologischem NNP cord-015369-72cjogxz 3723 8 Defizit Defizit NNP cord-015369-72cjogxz 3723 9 . . . cord-015369-72cjogxz 3724 1 Eine Eine NNP cord-015369-72cjogxz 3724 2 Computertomographie Computertomographie NNP cord-015369-72cjogxz 3724 3 der der NNP cord-015369-72cjogxz 3724 4 thorakalen thorakalen NNP cord-015369-72cjogxz 3725 1 Aorta aorta NN cord-015369-72cjogxz 3725 2 wurde wurde NN cord-015369-72cjogxz 3725 3 innerhalb innerhalb NNP cord-015369-72cjogxz 3725 4 der der NNP cord-015369-72cjogxz 3725 5 ersten ersten NNP cord-015369-72cjogxz 3725 6 zwei zwei CD cord-015369-72cjogxz 3725 7 Wochen Wochen NNP cord-015369-72cjogxz 3725 8 nach nach NN cord-015369-72cjogxz 3725 9 der der NNP cord-015369-72cjogxz 3725 10 Operation Operation NNP cord-015369-72cjogxz 3725 11 durchgeführt durchgeführt NN cord-015369-72cjogxz 3725 12 , , , cord-015369-72cjogxz 3725 13 dann dann NNP cord-015369-72cjogxz 3725 14 i -PRON- PRP cord-015369-72cjogxz 3725 15 m be VBP cord-015369-72cjogxz 3725 16 Abstand Abstand NNP cord-015369-72cjogxz 3725 17 von von NNP cord-015369-72cjogxz 3725 18 3 3 CD cord-015369-72cjogxz 3725 19 , , , cord-015369-72cjogxz 3725 20 6 6 CD cord-015369-72cjogxz 3725 21 und und CD cord-015369-72cjogxz 3725 22 12 12 CD cord-015369-72cjogxz 3725 23 Monaten Monaten NNP cord-015369-72cjogxz 3725 24 . . . cord-015369-72cjogxz 3726 1 Nach Nach NNP cord-015369-72cjogxz 3726 2 3 3 CD cord-015369-72cjogxz 3726 3 Monaten Monaten NNP cord-015369-72cjogxz 3726 4 zeigte zeigte NNP cord-015369-72cjogxz 3726 5 sich sich NNP cord-015369-72cjogxz 3726 6 bei bei NNP cord-015369-72cjogxz 3726 7 5 5 CD cord-015369-72cjogxz 3726 8 von von NNP cord-015369-72cjogxz 3726 9 6 6 CD cord-015369-72cjogxz 3726 10 Patienten Patienten NNP cord-015369-72cjogxz 3726 11 ( ( -LRB- cord-015369-72cjogxz 3726 12 83,3 83,3 CD cord-015369-72cjogxz 3726 13 % % NN cord-015369-72cjogxz 3726 14 ) ) -RRB- cord-015369-72cjogxz 3727 1 eine eine NNP cord-015369-72cjogxz 3727 2 komplette komplette NNP cord-015369-72cjogxz 3727 3 Thrombosierung Thrombosierung NNP cord-015369-72cjogxz 3727 4 des des FW cord-015369-72cjogxz 3727 5 falschen falschen NNP cord-015369-72cjogxz 3728 1 Lumens Lumens NNP cord-015369-72cjogxz 3728 2 bis bis NNP cord-015369-72cjogxz 3728 3 auf auf NNP cord-015369-72cjogxz 3728 4 Höhe Höhe NNPS cord-015369-72cjogxz 3728 5 des des NNP cord-015369-72cjogxz 3728 6 Stentgrafts Stentgrafts NNP cord-015369-72cjogxz 3728 7 . . . cord-015369-72cjogxz 3729 1 Ein Ein NNP cord-015369-72cjogxz 3729 2 Patient Patient NNP cord-015369-72cjogxz 3729 3 mit mit VBD cord-015369-72cjogxz 3729 4 chronischer chronischer NNP cord-015369-72cjogxz 3730 1 Typ Typ NNP cord-015369-72cjogxz 3730 2 A A NNP cord-015369-72cjogxz 3730 3 Dissektion Dissektion NNP cord-015369-72cjogxz 3730 4 erhielt erhielt NN cord-015369-72cjogxz 3730 5 5 5 CD cord-015369-72cjogxz 3730 6 Monate Monate NNP cord-015369-72cjogxz 3730 7 nach nach NNP cord-015369-72cjogxz 3730 8 dem dem NNP cord-015369-72cjogxz 3730 9 Ersteingriff Ersteingriff NNP cord-015369-72cjogxz 3730 10 einen einen NNP cord-015369-72cjogxz 3730 11 thorakoabdominellen thorakoabdominellen NN cord-015369-72cjogxz 3730 12 Aortenersatz Aortenersatz NNP cord-015369-72cjogxz 3730 13 . . . cord-015369-72cjogxz 3731 1 Der Der NNP cord-015369-72cjogxz 3731 2 Durchmesser Durchmesser NNP cord-015369-72cjogxz 3731 3 der der NNP cord-015369-72cjogxz 3731 4 Aorta Aorta NNP cord-015369-72cjogxz 3731 5 deszendens deszenden VBZ cord-015369-72cjogxz 3731 6 war war NN cord-015369-72cjogxz 3731 7 in in IN cord-015369-72cjogxz 3731 8 der der NNP cord-015369-72cjogxz 3731 9 Kontrolle Kontrolle NNP cord-015369-72cjogxz 3731 10 nach nach NNP cord-015369-72cjogxz 3731 11 12 12 CD cord-015369-72cjogxz 3731 12 Monaten Monaten NNP cord-015369-72cjogxz 3731 13 bei bei NNP cord-015369-72cjogxz 3731 14 5 5 CD cord-015369-72cjogxz 3731 15 Patienten Patienten NNP cord-015369-72cjogxz 3731 16 rückläufig rückläufig NN cord-015369-72cjogxz 3731 17 . . . cord-015369-72cjogxz 3732 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 3732 2 . . . cord-015369-72cjogxz 3733 1 Bei Bei NNP cord-015369-72cjogxz 3733 2 noch noch NNP cord-015369-72cjogxz 3733 3 geringer geringer NNP cord-015369-72cjogxz 3733 4 Fallzahl Fallzahl NNPS cord-015369-72cjogxz 3733 5 zeigen zeigen NNP cord-015369-72cjogxz 3733 6 die die VBP cord-015369-72cjogxz 3733 7 positiven positiven NNP cord-015369-72cjogxz 3733 8 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 3733 9 , , , cord-015369-72cjogxz 3733 10 dass dass NNP cord-015369-72cjogxz 3733 11 der der NNP cord-015369-72cjogxz 3733 12 simultane simultane NNP cord-015369-72cjogxz 3733 13 chirurgische chirurgische NNP cord-015369-72cjogxz 3733 14 und und IN cord-015369-72cjogxz 3733 15 endovaskuläre endovaskuläre NNP cord-015369-72cjogxz 3733 16 Zugang Zugang NNP cord-015369-72cjogxz 3734 1 für für NNP cord-015369-72cjogxz 3734 2 die die VBP cord-015369-72cjogxz 3734 3 erweiterte erweiterte NNS cord-015369-72cjogxz 3735 1 Therapie Therapie NNP cord-015369-72cjogxz 3735 2 der der NN cord-015369-72cjogxz 3735 3 Typ Typ NNP cord-015369-72cjogxz 3735 4 A A NNP cord-015369-72cjogxz 3735 5 Dissektion Dissektion NNP cord-015369-72cjogxz 3735 6 eine eine FW cord-015369-72cjogxz 3735 7 gute gute JJ cord-015369-72cjogxz 3735 8 Behandlungsmöglichkeit Behandlungsmöglichkeit NNP cord-015369-72cjogxz 3735 9 darstellt darstellt NNP cord-015369-72cjogxz 3735 10 , , , cord-015369-72cjogxz 3735 11 ohne ohne NNP cord-015369-72cjogxz 3735 12 das das NNP cord-015369-72cjogxz 3735 13 perioperative perioperative JJ cord-015369-72cjogxz 3735 14 Risiko Risiko NNP cord-015369-72cjogxz 3735 15 zu zu NNP cord-015369-72cjogxz 3735 16 erhöhen erhöhen NNP cord-015369-72cjogxz 3735 17 . . . cord-015369-72cjogxz 3736 1 From from IN cord-015369-72cjogxz 3736 2 trunk trunk NN cord-015369-72cjogxz 3736 3 to to IN cord-015369-72cjogxz 3736 4 trunkstent trunkstent NN cord-015369-72cjogxz 3736 5 - - HYPH cord-015369-72cjogxz 3736 6 graft graft NN cord-015369-72cjogxz 3736 7 coverage coverage NN cord-015369-72cjogxz 3736 8 of of IN cord-015369-72cjogxz 3736 9 the the DT cord-015369-72cjogxz 3736 10 entire entire JJ cord-015369-72cjogxz 3736 11 thoracic thoracic JJ cord-015369-72cjogxz 3736 12 aorta aorta NN cord-015369-72cjogxz 3736 13 Background Background NNP cord-015369-72cjogxz 3736 14 . . . cord-015369-72cjogxz 3737 1 Aim aim VB cord-015369-72cjogxz 3737 2 of of IN cord-015369-72cjogxz 3737 3 this this DT cord-015369-72cjogxz 3737 4 study study NN cord-015369-72cjogxz 3737 5 was be VBD cord-015369-72cjogxz 3737 6 to to TO cord-015369-72cjogxz 3737 7 determine determine VB cord-015369-72cjogxz 3737 8 safety safety NN cord-015369-72cjogxz 3737 9 and and CC cord-015369-72cjogxz 3737 10 practicability practicability NN cord-015369-72cjogxz 3737 11 of of IN cord-015369-72cjogxz 3737 12 stent stent NN cord-015369-72cjogxz 3737 13 - - HYPH cord-015369-72cjogxz 3737 14 graft graft NN cord-015369-72cjogxz 3737 15 placement placement NN cord-015369-72cjogxz 3737 16 in in IN cord-015369-72cjogxz 3737 17 patients patient NNS cord-015369-72cjogxz 3737 18 requiring require VBG cord-015369-72cjogxz 3737 19 coverage coverage NN cord-015369-72cjogxz 3737 20 of of IN cord-015369-72cjogxz 3737 21 the the DT cord-015369-72cjogxz 3737 22 entire entire JJ cord-015369-72cjogxz 3737 23 descending descend VBG cord-015369-72cjogxz 3737 24 aorta aorta NN cord-015369-72cjogxz 3737 25 . . . cord-015369-72cjogxz 3738 1 Methods method NNS cord-015369-72cjogxz 3738 2 . . . cord-015369-72cjogxz 3739 1 From from IN cord-015369-72cjogxz 3739 2 2005 2005 CD cord-015369-72cjogxz 3739 3 through through IN cord-015369-72cjogxz 3739 4 2008 2008 CD cord-015369-72cjogxz 3739 5 , , , cord-015369-72cjogxz 3739 6 15 15 CD cord-015369-72cjogxz 3739 7 patients patient NNS cord-015369-72cjogxz 3739 8 ( ( -LRB- cord-015369-72cjogxz 3739 9 male male JJ cord-015369-72cjogxz 3739 10 ¼ ¼ NNP cord-015369-72cjogxz 3739 11 8 8 CD cord-015369-72cjogxz 3739 12 , , , cord-015369-72cjogxz 3739 13 mean mean VB cord-015369-72cjogxz 3739 14 age age NN cord-015369-72cjogxz 3739 15 69a 69a NNS cord-015369-72cjogxz 3739 16 ) ) -RRB- cord-015369-72cjogxz 3740 1 underwent undergo VBD cord-015369-72cjogxz 3740 2 stent stent JJ cord-015369-72cjogxz 3740 3 - - HYPH cord-015369-72cjogxz 3740 4 graft graft NN cord-015369-72cjogxz 3740 5 placement placement NN cord-015369-72cjogxz 3740 6 from from IN cord-015369-72cjogxz 3740 7 brachiocephalic brachiocephalic NNP cord-015369-72cjogxz 3740 8 to to IN cord-015369-72cjogxz 3740 9 celiac celiac NNP cord-015369-72cjogxz 3740 10 trunk trunk NN cord-015369-72cjogxz 3740 11 . . . cord-015369-72cjogxz 3741 1 All all DT cord-015369-72cjogxz 3741 2 patients patient NNS cord-015369-72cjogxz 3741 3 underwent undergo VBD cord-015369-72cjogxz 3741 4 rerouting reroute VBG cord-015369-72cjogxz 3741 5 of of IN cord-015369-72cjogxz 3741 6 the the DT cord-015369-72cjogxz 3741 7 supraaortic supraaortic JJ cord-015369-72cjogxz 3741 8 branches branch NNS cord-015369-72cjogxz 3741 9 to to TO cord-015369-72cjogxz 3741 10 gain gain VB cord-015369-72cjogxz 3741 11 sufficient sufficient JJ cord-015369-72cjogxz 3741 12 proximal proximal JJ cord-015369-72cjogxz 3741 13 landing landing NN cord-015369-72cjogxz 3741 14 zone zone NN cord-015369-72cjogxz 3741 15 . . . cord-015369-72cjogxz 3742 1 Indications indication NNS cord-015369-72cjogxz 3742 2 for for IN cord-015369-72cjogxz 3742 3 stent stent JJ cord-015369-72cjogxz 3742 4 - - HYPH cord-015369-72cjogxz 3742 5 graft graft NN cord-015369-72cjogxz 3742 6 placement placement NN cord-015369-72cjogxz 3742 7 were be VBD cord-015369-72cjogxz 3742 8 aneurysms aneurysm NNS cord-015369-72cjogxz 3742 9 ( ( -LRB- cord-015369-72cjogxz 3742 10 n n CC cord-015369-72cjogxz 3742 11 ¼ ¼ NNP cord-015369-72cjogxz 3742 12 9 9 CD cord-015369-72cjogxz 3742 13 ) ) -RRB- cord-015369-72cjogxz 3742 14 and and CC cord-015369-72cjogxz 3742 15 penetrating penetrate VBG cord-015369-72cjogxz 3742 16 ulcers ulcer NNS cord-015369-72cjogxz 3742 17 ( ( -LRB- cord-015369-72cjogxz 3742 18 n n NN cord-015369-72cjogxz 3742 19 ¼ ¼ NNP cord-015369-72cjogxz 3742 20 6 6 CD cord-015369-72cjogxz 3742 21 ) ) -RRB- cord-015369-72cjogxz 3742 22 . . . cord-015369-72cjogxz 3743 1 CSF CSF NNP cord-015369-72cjogxz 3743 2 drainage drainage NN cord-015369-72cjogxz 3743 3 was be VBD cord-015369-72cjogxz 3743 4 initiated initiate VBN cord-015369-72cjogxz 3743 5 only only RB cord-015369-72cjogxz 3743 6 in in IN cord-015369-72cjogxz 3743 7 case case NN cord-015369-72cjogxz 3743 8 of of IN cord-015369-72cjogxz 3743 9 neurologic neurologic JJ cord-015369-72cjogxz 3743 10 symptoms symptom NNS cord-015369-72cjogxz 3743 11 . . . cord-015369-72cjogxz 3744 1 In in IN cord-015369-72cjogxz 3744 2 all all DT cord-015369-72cjogxz 3744 3 patients patient NNS cord-015369-72cjogxz 3744 4 mean mean VBP cord-015369-72cjogxz 3744 5 blood blood NN cord-015369-72cjogxz 3744 6 pressure pressure NN cord-015369-72cjogxz 3744 7 was be VBD cord-015369-72cjogxz 3744 8 kept keep VBN cord-015369-72cjogxz 3744 9 above above IN cord-015369-72cjogxz 3744 10 80 80 CD cord-015369-72cjogxz 3744 11 MmHg MmHg NNS cord-015369-72cjogxz 3744 12 for for IN cord-015369-72cjogxz 3744 13 96 96 CD cord-015369-72cjogxz 3744 14 hours hour NNS cord-015369-72cjogxz 3744 15 after after IN cord-015369-72cjogxz 3744 16 stent stent NN cord-015369-72cjogxz 3744 17 - - HYPH cord-015369-72cjogxz 3744 18 graft graft NN cord-015369-72cjogxz 3744 19 placement placement NN cord-015369-72cjogxz 3744 20 . . . cord-015369-72cjogxz 3745 1 Results result NNS cord-015369-72cjogxz 3745 2 . . . cord-015369-72cjogxz 3746 1 Arch arch JJ cord-015369-72cjogxz 3746 2 rerouting rerouting NN cord-015369-72cjogxz 3746 3 and and CC cord-015369-72cjogxz 3746 4 stent stent NN cord-015369-72cjogxz 3746 5 - - HYPH cord-015369-72cjogxz 3746 6 graft graft NN cord-015369-72cjogxz 3746 7 placement placement NN cord-015369-72cjogxz 3746 8 were be VBD cord-015369-72cjogxz 3746 9 performed perform VBN cord-015369-72cjogxz 3746 10 successfully successfully RB cord-015369-72cjogxz 3746 11 in in IN cord-015369-72cjogxz 3746 12 all all DT cord-015369-72cjogxz 3746 13 patients patient NNS cord-015369-72cjogxz 3746 14 . . . cord-015369-72cjogxz 3747 1 One one CD cord-015369-72cjogxz 3747 2 early early JJ cord-015369-72cjogxz 3747 3 type type NN cord-015369-72cjogxz 3747 4 III III NNP cord-015369-72cjogxz 3747 5 endoleak endoleak NNP cord-015369-72cjogxz 3747 6 was be VBD cord-015369-72cjogxz 3747 7 observed observe VBN cord-015369-72cjogxz 3747 8 and and CC cord-015369-72cjogxz 3747 9 treated treat VBN cord-015369-72cjogxz 3747 10 by by IN cord-015369-72cjogxz 3747 11 overstenting overstente VBG cord-015369-72cjogxz 3747 12 . . . cord-015369-72cjogxz 3748 1 No no DT cord-015369-72cjogxz 3748 2 late late JJ cord-015369-72cjogxz 3748 3 endoleaks endoleak NNS cord-015369-72cjogxz 3748 4 occured occur VBD cord-015369-72cjogxz 3748 5 . . . cord-015369-72cjogxz 3749 1 Symptoms symptom NNS cord-015369-72cjogxz 3749 2 of of IN cord-015369-72cjogxz 3749 3 spinal spinal JJ cord-015369-72cjogxz 3749 4 cord cord NN cord-015369-72cjogxz 3749 5 malperfusion malperfusion NN cord-015369-72cjogxz 3749 6 were be VBD cord-015369-72cjogxz 3749 7 observed observe VBN cord-015369-72cjogxz 3749 8 in in IN cord-015369-72cjogxz 3749 9 2 2 CD cord-015369-72cjogxz 3749 10 patients patient NNS cord-015369-72cjogxz 3749 11 ( ( -LRB- cord-015369-72cjogxz 3749 12 13.3 13.3 CD cord-015369-72cjogxz 3749 13 % % NN cord-015369-72cjogxz 3749 14 ) ) -RRB- cord-015369-72cjogxz 3749 15 . . . cord-015369-72cjogxz 3750 1 In in IN cord-015369-72cjogxz 3750 2 one one CD cord-015369-72cjogxz 3750 3 patient patient JJ cord-015369-72cjogxz 3750 4 paraplegia paraplegia NN cord-015369-72cjogxz 3750 5 was be VBD cord-015369-72cjogxz 3750 6 seen see VBN cord-015369-72cjogxz 3750 7 , , , cord-015369-72cjogxz 3750 8 resolving resolve VBG cord-015369-72cjogxz 3750 9 after after IN cord-015369-72cjogxz 3750 10 CSF CSF NNP cord-015369-72cjogxz 3750 11 drainage drainage NN cord-015369-72cjogxz 3750 12 ( ( -LRB- cord-015369-72cjogxz 3750 13 6.7 6.7 CD cord-015369-72cjogxz 3750 14 % % NN cord-015369-72cjogxz 3750 15 ) ) -RRB- cord-015369-72cjogxz 3750 16 . . . cord-015369-72cjogxz 3751 1 Another another DT cord-015369-72cjogxz 3751 2 patient patient NN cord-015369-72cjogxz 3751 3 developed develop VBD cord-015369-72cjogxz 3751 4 signs sign NNS cord-015369-72cjogxz 3751 5 of of IN cord-015369-72cjogxz 3751 6 chronic chronic JJ cord-015369-72cjogxz 3751 7 spinal spinal JJ cord-015369-72cjogxz 3751 8 cord cord NN cord-015369-72cjogxz 3751 9 ischemia ischemia NN cord-015369-72cjogxz 3751 10 ( ( -LRB- cord-015369-72cjogxz 3751 11 6.7 6.7 CD cord-015369-72cjogxz 3751 12 % % NN cord-015369-72cjogxz 3751 13 ) ) -RRB- cord-015369-72cjogxz 3751 14 . . . cord-015369-72cjogxz 3752 1 This this DT cord-015369-72cjogxz 3752 2 patient patient NN cord-015369-72cjogxz 3752 3 had have VBD cord-015369-72cjogxz 3752 4 undergone undergo VBN cord-015369-72cjogxz 3752 5 replacement replacement NN cord-015369-72cjogxz 3752 6 of of IN cord-015369-72cjogxz 3752 7 the the DT cord-015369-72cjogxz 3752 8 abdominal abdominal JJ cord-015369-72cjogxz 3752 9 aorta aorta NN cord-015369-72cjogxz 3752 10 6 6 CD cord-015369-72cjogxz 3752 11 years year NNS cord-015369-72cjogxz 3752 12 prior prior RB cord-015369-72cjogxz 3752 13 to to IN cord-015369-72cjogxz 3752 14 stent stent JJ cord-015369-72cjogxz 3752 15 - - HYPH cord-015369-72cjogxz 3752 16 graft graft NN cord-015369-72cjogxz 3752 17 placement placement NN cord-015369-72cjogxz 3752 18 . . . cord-015369-72cjogxz 3753 1 In in IN cord-015369-72cjogxz 3753 2 all all DT cord-015369-72cjogxz 3753 3 other other JJ cord-015369-72cjogxz 3753 4 patients patient NNS cord-015369-72cjogxz 3753 5 no no DT cord-015369-72cjogxz 3753 6 signs sign NNS cord-015369-72cjogxz 3753 7 of of IN cord-015369-72cjogxz 3753 8 spinal spinal JJ cord-015369-72cjogxz 3753 9 cord cord NN cord-015369-72cjogxz 3753 10 malperfusion malperfusion NN cord-015369-72cjogxz 3753 11 could could MD cord-015369-72cjogxz 3753 12 be be VB cord-015369-72cjogxz 3753 13 detected detect VBN cord-015369-72cjogxz 3753 14 . . . cord-015369-72cjogxz 3754 1 Conclusions conclusion NNS cord-015369-72cjogxz 3754 2 . . . cord-015369-72cjogxz 3755 1 This this DT cord-015369-72cjogxz 3755 2 study study NN cord-015369-72cjogxz 3755 3 outlines outline VBZ cord-015369-72cjogxz 3755 4 the the DT cord-015369-72cjogxz 3755 5 safety safety NN cord-015369-72cjogxz 3755 6 and and CC cord-015369-72cjogxz 3755 7 practicability practicability NN cord-015369-72cjogxz 3755 8 of of IN cord-015369-72cjogxz 3755 9 the the DT cord-015369-72cjogxz 3755 10 complete complete JJ cord-015369-72cjogxz 3755 11 coverage coverage NN cord-015369-72cjogxz 3755 12 of of IN cord-015369-72cjogxz 3755 13 the the DT cord-015369-72cjogxz 3755 14 descending descend VBG cord-015369-72cjogxz 3755 15 aorta aorta NN cord-015369-72cjogxz 3755 16 from from IN cord-015369-72cjogxz 3755 17 trunk trunk NN cord-015369-72cjogxz 3755 18 to to IN cord-015369-72cjogxz 3755 19 trunk trunk NN cord-015369-72cjogxz 3755 20 . . . cord-015369-72cjogxz 3756 1 The the DT cord-015369-72cjogxz 3756 2 low low JJ cord-015369-72cjogxz 3756 3 number number NN cord-015369-72cjogxz 3756 4 neurologic neurologic JJ cord-015369-72cjogxz 3756 5 complications complication NNS cord-015369-72cjogxz 3756 6 could could MD cord-015369-72cjogxz 3756 7 be be VB cord-015369-72cjogxz 3756 8 explained explain VBN cord-015369-72cjogxz 3756 9 by by IN cord-015369-72cjogxz 3756 10 aggressive aggressive JJ cord-015369-72cjogxz 3756 11 rerouting rerouting NN cord-015369-72cjogxz 3756 12 procedures procedure NNS cord-015369-72cjogxz 3756 13 resulting result VBG cord-015369-72cjogxz 3756 14 in in IN cord-015369-72cjogxz 3756 15 sufficient sufficient JJ cord-015369-72cjogxz 3756 16 collateral collateral JJ cord-015369-72cjogxz 3756 17 flow flow NN cord-015369-72cjogxz 3756 18 from from IN cord-015369-72cjogxz 3756 19 the the DT cord-015369-72cjogxz 3756 20 left left JJ cord-015369-72cjogxz 3756 21 subclavian subclavian JJ cord-015369-72cjogxz 3756 22 artery artery NN cord-015369-72cjogxz 3756 23 and and CC cord-015369-72cjogxz 3756 24 the the DT cord-015369-72cjogxz 3756 25 intended intend VBN cord-015369-72cjogxz 3756 26 elevation elevation NN cord-015369-72cjogxz 3756 27 of of IN cord-015369-72cjogxz 3756 28 postoperative postoperative JJ cord-015369-72cjogxz 3756 29 blood blood NN cord-015369-72cjogxz 3756 30 pressure pressure NN cord-015369-72cjogxz 3756 31 . . . cord-015369-72cjogxz 3757 1 CSF CSF NNP cord-015369-72cjogxz 3757 2 drainage drainage NN cord-015369-72cjogxz 3757 3 is be VBZ cord-015369-72cjogxz 3757 4 not not RB cord-015369-72cjogxz 3757 5 required require VBN cord-015369-72cjogxz 3757 6 on on IN cord-015369-72cjogxz 3757 7 a a DT cord-015369-72cjogxz 3757 8 regular regular JJ cord-015369-72cjogxz 3757 9 basis basis NN cord-015369-72cjogxz 3757 10 in in IN cord-015369-72cjogxz 3757 11 these these DT cord-015369-72cjogxz 3757 12 patients patient NNS cord-015369-72cjogxz 3757 13 . . . cord-015369-72cjogxz 3758 1 Endovascular Endovascular NNP cord-015369-72cjogxz 3758 2 stent stent NN cord-015369-72cjogxz 3758 3 - - HYPH cord-015369-72cjogxz 3758 4 graft graft NN cord-015369-72cjogxz 3758 5 placement placement NN cord-015369-72cjogxz 3758 6 in in IN cord-015369-72cjogxz 3758 7 atherosclerotic atherosclerotic JJ cord-015369-72cjogxz 3758 8 aneurysms aneurysm NNS cord-015369-72cjogxz 3758 9 involving involve VBG cord-015369-72cjogxz 3758 10 the the DT cord-015369-72cjogxz 3758 11 descending descend VBG cord-015369-72cjogxz 3758 12 aortalong aortalong JJ cord-015369-72cjogxz 3758 13 - - HYPH cord-015369-72cjogxz 3758 14 term term NN cord-015369-72cjogxz 3758 15 results result NNS cord-015369-72cjogxz 3758 16 Background Background NNP cord-015369-72cjogxz 3758 17 . . . cord-015369-72cjogxz 3759 1 To to TO cord-015369-72cjogxz 3759 2 determine determine VB cord-015369-72cjogxz 3759 3 long long JJ cord-015369-72cjogxz 3759 4 - - HYPH cord-015369-72cjogxz 3759 5 term term NN cord-015369-72cjogxz 3759 6 durability durability NN cord-015369-72cjogxz 3759 7 and and CC cord-015369-72cjogxz 3759 8 need need NN cord-015369-72cjogxz 3759 9 for for IN cord-015369-72cjogxz 3759 10 reinterventions reintervention NNS cord-015369-72cjogxz 3759 11 after after IN cord-015369-72cjogxz 3759 12 endovascular endovascular JJ cord-015369-72cjogxz 3759 13 stent stent JJ cord-015369-72cjogxz 3759 14 - - HYPH cord-015369-72cjogxz 3759 15 graft graft NN cord-015369-72cjogxz 3759 16 placement placement NN cord-015369-72cjogxz 3759 17 in in IN cord-015369-72cjogxz 3759 18 atherosclerotic atherosclerotic JJ cord-015369-72cjogxz 3759 19 aneurysms aneurysm NNS cord-015369-72cjogxz 3759 20 involving involve VBG cord-015369-72cjogxz 3759 21 the the DT cord-015369-72cjogxz 3759 22 descending descend VBG cord-015369-72cjogxz 3759 23 aorta aorta NN cord-015369-72cjogxz 3759 24 . . . cord-015369-72cjogxz 3760 1 Methods method NNS cord-015369-72cjogxz 3760 2 . . . cord-015369-72cjogxz 3761 1 We -PRON- PRP cord-015369-72cjogxz 3761 2 performed perform VBD cord-015369-72cjogxz 3761 3 a a DT cord-015369-72cjogxz 3761 4 prospective prospective JJ cord-015369-72cjogxz 3761 5 follow follow NN cord-015369-72cjogxz 3761 6 - - HYPH cord-015369-72cjogxz 3761 7 up up NN cord-015369-72cjogxz 3761 8 analysis analysis NN cord-015369-72cjogxz 3761 9 of of IN cord-015369-72cjogxz 3761 10 a a DT cord-015369-72cjogxz 3761 11 consecutive consecutive JJ cord-015369-72cjogxz 3761 12 series series NN cord-015369-72cjogxz 3761 13 of of IN cord-015369-72cjogxz 3761 14 patients patient NNS cord-015369-72cjogxz 3761 15 ( ( -LRB- cord-015369-72cjogxz 3761 16 n n NNP cord-015369-72cjogxz 3761 17 ¼ ¼ NNP cord-015369-72cjogxz 3761 18 100 100 CD cord-015369-72cjogxz 3761 19 ) ) -RRB- cord-015369-72cjogxz 3761 20 undergoing undergo VBG cord-015369-72cjogxz 3761 21 endovascular endovascular JJ cord-015369-72cjogxz 3761 22 stent stent JJ cord-015369-72cjogxz 3761 23 - - HYPH cord-015369-72cjogxz 3761 24 graft graft NN cord-015369-72cjogxz 3761 25 placement placement NN cord-015369-72cjogxz 3761 26 due due IN cord-015369-72cjogxz 3761 27 to to IN cord-015369-72cjogxz 3761 28 atherosclerotic atherosclerotic JJ cord-015369-72cjogxz 3761 29 aneurysms aneurysm NNS cord-015369-72cjogxz 3761 30 involving involve VBG cord-015369-72cjogxz 3761 31 the the DT cord-015369-72cjogxz 3761 32 descending descend VBG cord-015369-72cjogxz 3761 33 aorta aorta NN cord-015369-72cjogxz 3761 34 between between IN cord-015369-72cjogxz 3761 35 1996 1996 CD cord-015369-72cjogxz 3761 36 and and CC cord-015369-72cjogxz 3761 37 2007 2007 CD cord-015369-72cjogxz 3761 38 . . . cord-015369-72cjogxz 3762 1 Outcome outcome NN cord-015369-72cjogxz 3762 2 variables variable NNS cord-015369-72cjogxz 3762 3 included include VBD cord-015369-72cjogxz 3762 4 death death NN cord-015369-72cjogxz 3762 5 , , , cord-015369-72cjogxz 3762 6 occurrence occurrence NN cord-015369-72cjogxz 3762 7 of of IN cord-015369-72cjogxz 3762 8 early early JJ cord-015369-72cjogxz 3762 9 and and CC cord-015369-72cjogxz 3762 10 late late JJ cord-015369-72cjogxz 3762 11 type type NN cord-015369-72cjogxz 3762 12 I -PRON- PRP cord-015369-72cjogxz 3762 13 and and CC cord-015369-72cjogxz 3762 14 II II NNP cord-015369-72cjogxz 3762 15 endoleak endoleak NNP cord-015369-72cjogxz 3762 16 formation formation NN cord-015369-72cjogxz 3762 17 , , , cord-015369-72cjogxz 3762 18 the the DT cord-015369-72cjogxz 3762 19 rate rate NN cord-015369-72cjogxz 3762 20 of of IN cord-015369-72cjogxz 3762 21 reintervention reintervention NN cord-015369-72cjogxz 3762 22 due due IN cord-015369-72cjogxz 3762 23 to to IN cord-015369-72cjogxz 3762 24 early early JJ cord-015369-72cjogxz 3762 25 and and CC cord-015369-72cjogxz 3762 26 late late JJ cord-015369-72cjogxz 3762 27 endoleak endoleak NNP cord-015369-72cjogxz 3762 28 formation formation NN cord-015369-72cjogxz 3762 29 and and CC cord-015369-72cjogxz 3762 30 the the DT cord-015369-72cjogxz 3762 31 survival survival NN cord-015369-72cjogxz 3762 32 of of IN cord-015369-72cjogxz 3762 33 the the DT cord-015369-72cjogxz 3762 34 patients patient NNS cord-015369-72cjogxz 3762 35 . . . cord-015369-72cjogxz 3763 1 Median median JJ cord-015369-72cjogxz 3763 2 follow follow NN cord-015369-72cjogxz 3763 3 - - HYPH cord-015369-72cjogxz 3763 4 up up NN cord-015369-72cjogxz 3763 5 was be VBD cord-015369-72cjogxz 3763 6 50 50 CD cord-015369-72cjogxz 3763 7 ( ( -LRB- cord-015369-72cjogxz 3763 8 1 1 CD cord-015369-72cjogxz 3763 9 - - SYM cord-015369-72cjogxz 3763 10 120 120 CD cord-015369-72cjogxz 3763 11 ) ) -RRB- cord-015369-72cjogxz 3763 12 months month NNS cord-015369-72cjogxz 3763 13 . . . cord-015369-72cjogxz 3764 1 Results result NNS cord-015369-72cjogxz 3764 2 . . . cord-015369-72cjogxz 3765 1 In in IN cord-015369-72cjogxz 3765 2 - - HYPH cord-015369-72cjogxz 3765 3 hospital hospital NN cord-015369-72cjogxz 3765 4 mortality mortality NN cord-015369-72cjogxz 3765 5 was be VBD cord-015369-72cjogxz 3765 6 9 9 CD cord-015369-72cjogxz 3765 7 % % NN cord-015369-72cjogxz 3765 8 , , , cord-015369-72cjogxz 3765 9 whereas whereas IN cord-015369-72cjogxz 3765 10 two two CD cord-015369-72cjogxz 3765 11 third third NN cord-015369-72cjogxz 3765 12 of of IN cord-015369-72cjogxz 3765 13 these these DT cord-015369-72cjogxz 3765 14 patients patient NNS cord-015369-72cjogxz 3765 15 underwent undergo VBD cord-015369-72cjogxz 3765 16 stent stent JJ cord-015369-72cjogxz 3765 17 - - HYPH cord-015369-72cjogxz 3765 18 graft graft NN cord-015369-72cjogxz 3765 19 placement placement NN cord-015369-72cjogxz 3765 20 in in IN cord-015369-72cjogxz 3765 21 the the DT cord-015369-72cjogxz 3765 22 acute acute JJ cord-015369-72cjogxz 3765 23 setting setting NN cord-015369-72cjogxz 3765 24 . . . cord-015369-72cjogxz 3766 1 Assisted assisted JJ cord-015369-72cjogxz 3766 2 primary primary JJ cord-015369-72cjogxz 3766 3 endoleak endoleak NN cord-015369-72cjogxz 3766 4 rate rate NN cord-015369-72cjogxz 3766 5 was be VBD cord-015369-72cjogxz 3766 6 11 11 CD cord-015369-72cjogxz 3766 7 % % NN cord-015369-72cjogxz 3766 8 . . . cord-015369-72cjogxz 3767 1 Assisted assisted JJ cord-015369-72cjogxz 3767 2 secondary secondary JJ cord-015369-72cjogxz 3767 3 primary primary JJ cord-015369-72cjogxz 3767 4 rate rate NN cord-015369-72cjogxz 3767 5 was be VBD cord-015369-72cjogxz 3767 6 13 13 CD cord-015369-72cjogxz 3767 7 % % NN cord-015369-72cjogxz 3767 8 . . . cord-015369-72cjogxz 3768 1 Actuarial actuarial JJ cord-015369-72cjogxz 3768 2 survival survival NN cord-015369-72cjogxz 3768 3 rates rate NNS cord-015369-72cjogxz 3768 4 at at IN cord-015369-72cjogxz 3768 5 1 1 CD cord-015369-72cjogxz 3768 6 , , , cord-015369-72cjogxz 3768 7 3 3 CD cord-015369-72cjogxz 3768 8 and and CC cord-015369-72cjogxz 3768 9 5 5 CD cord-015369-72cjogxz 3768 10 years year NNS cord-015369-72cjogxz 3768 11 were be VBD cord-015369-72cjogxz 3768 12 96 96 CD cord-015369-72cjogxz 3768 13 % % NN cord-015369-72cjogxz 3768 14 , , , cord-015369-72cjogxz 3768 15 86 86 CD cord-015369-72cjogxz 3768 16 % % NN cord-015369-72cjogxz 3768 17 and and CC cord-015369-72cjogxz 3768 18 69 69 CD cord-015369-72cjogxz 3768 19 % % NN cord-015369-72cjogxz 3768 20 respectively respectively RB cord-015369-72cjogxz 3768 21 . . . cord-015369-72cjogxz 3769 1 A a DT cord-015369-72cjogxz 3769 2 short short JJ cord-015369-72cjogxz 3769 3 proximal proximal JJ cord-015369-72cjogxz 3769 4 landing landing NN cord-015369-72cjogxz 3769 5 zone zone NN cord-015369-72cjogxz 3769 6 and and CC cord-015369-72cjogxz 3769 7 a a DT cord-015369-72cjogxz 3769 8 high high JJ cord-015369-72cjogxz 3769 9 number number NN cord-015369-72cjogxz 3769 10 of of IN cord-015369-72cjogxz 3769 11 implanted implant VBN cord-015369-72cjogxz 3769 12 stent stent NN cord-015369-72cjogxz 3769 13 - - HYPH cord-015369-72cjogxz 3769 14 grafts graft NNS cord-015369-72cjogxz 3769 15 were be VBD cord-015369-72cjogxz 3769 16 identified identify VBN cord-015369-72cjogxz 3769 17 as as IN cord-015369-72cjogxz 3769 18 independent independent JJ cord-015369-72cjogxz 3769 19 predictors predictor NNS cord-015369-72cjogxz 3769 20 of of IN cord-015369-72cjogxz 3769 21 the the DT cord-015369-72cjogxz 3769 22 occurrence occurrence NN cord-015369-72cjogxz 3769 23 of of IN cord-015369-72cjogxz 3769 24 early early JJ cord-015369-72cjogxz 3769 25 and and CC cord-015369-72cjogxz 3769 26 late late JJ cord-015369-72cjogxz 3769 27 endoleak endoleak NN cord-015369-72cjogxz 3769 28 formation formation NN cord-015369-72cjogxz 3769 29 . . . cord-015369-72cjogxz 3770 1 The the DT cord-015369-72cjogxz 3770 2 occurrence occurrence NN cord-015369-72cjogxz 3770 3 of of IN cord-015369-72cjogxz 3770 4 late late JJ cord-015369-72cjogxz 3770 5 endoleak endoleak NNP cord-015369-72cjogxz 3770 6 formation formation NN cord-015369-72cjogxz 3770 7 appeared appear VBD cord-015369-72cjogxz 3770 8 to to TO cord-015369-72cjogxz 3770 9 be be VB cord-015369-72cjogxz 3770 10 an an DT cord-015369-72cjogxz 3770 11 independent independent JJ cord-015369-72cjogxz 3770 12 predictor predictor NN cord-015369-72cjogxz 3770 13 with with IN cord-015369-72cjogxz 3770 14 regard regard NN cord-015369-72cjogxz 3770 15 to to IN cord-015369-72cjogxz 3770 16 survival survival NN cord-015369-72cjogxz 3770 17 . . . cord-015369-72cjogxz 3771 1 Conclusions conclusion NNS cord-015369-72cjogxz 3771 2 . . . cord-015369-72cjogxz 3772 1 Long long JJ cord-015369-72cjogxz 3772 2 - - HYPH cord-015369-72cjogxz 3772 3 term term NN cord-015369-72cjogxz 3772 4 durability durability NN cord-015369-72cjogxz 3772 5 of of IN cord-015369-72cjogxz 3772 6 endovascular endovascular JJ cord-015369-72cjogxz 3772 7 stentgraft stentgraft NN cord-015369-72cjogxz 3772 8 placement placement NN cord-015369-72cjogxz 3772 9 in in IN cord-015369-72cjogxz 3772 10 atherosclerotic atherosclerotic JJ cord-015369-72cjogxz 3772 11 aneurysms aneurysm NNS cord-015369-72cjogxz 3772 12 involving involve VBG cord-015369-72cjogxz 3772 13 the the DT cord-015369-72cjogxz 3772 14 descending descend VBG cord-015369-72cjogxz 3772 15 aorta aorta NN cord-015369-72cjogxz 3772 16 is be VBZ cord-015369-72cjogxz 3772 17 satisfying satisfy VBG cord-015369-72cjogxz 3772 18 and and CC cord-015369-72cjogxz 3772 19 the the DT cord-015369-72cjogxz 3772 20 need need NN cord-015369-72cjogxz 3772 21 for for IN cord-015369-72cjogxz 3772 22 reintervention reintervention NN cord-015369-72cjogxz 3772 23 is be VBZ cord-015369-72cjogxz 3772 24 acceptably acceptably RB cord-015369-72cjogxz 3772 25 low low JJ cord-015369-72cjogxz 3772 26 . . . cord-015369-72cjogxz 3773 1 An an DT cord-015369-72cjogxz 3773 2 extensive extensive JJ cord-015369-72cjogxz 3773 3 landing landing NN cord-015369-72cjogxz 3773 4 zone zone NN cord-015369-72cjogxz 3773 5 and and CC cord-015369-72cjogxz 3773 6 a a DT cord-015369-72cjogxz 3773 7 low low JJ cord-015369-72cjogxz 3773 8 number number NN cord-015369-72cjogxz 3773 9 of of IN cord-015369-72cjogxz 3773 10 stent stent NN cord-015369-72cjogxz 3773 11 - - HYPH cord-015369-72cjogxz 3773 12 grafts graft NNS cord-015369-72cjogxz 3773 13 are be VBP cord-015369-72cjogxz 3773 14 mandatory mandatory JJ cord-015369-72cjogxz 3773 15 for for IN cord-015369-72cjogxz 3773 16 early early JJ cord-015369-72cjogxz 3773 17 and and CC cord-015369-72cjogxz 3773 18 late late JJ cord-015369-72cjogxz 3773 19 success success NN cord-015369-72cjogxz 3773 20 . . . cord-015369-72cjogxz 3774 1 Background background NN cord-015369-72cjogxz 3774 2 . . . cord-015369-72cjogxz 3775 1 Swedish swedish JJ cord-015369-72cjogxz 3775 2 adjustable adjustable JJ cord-015369-72cjogxz 3775 3 gastric gastric JJ cord-015369-72cjogxz 3775 4 banding banding NN cord-015369-72cjogxz 3775 5 ( ( -LRB- cord-015369-72cjogxz 3775 6 SAGB SAGB NNP cord-015369-72cjogxz 3775 7 ) ) -RRB- cord-015369-72cjogxz 3775 8 is be VBZ cord-015369-72cjogxz 3775 9 an an DT cord-015369-72cjogxz 3775 10 effective effective JJ cord-015369-72cjogxz 3775 11 treatment treatment NN cord-015369-72cjogxz 3775 12 for for IN cord-015369-72cjogxz 3775 13 morbid morbid JJ cord-015369-72cjogxz 3775 14 obesity obesity NN cord-015369-72cjogxz 3775 15 . . . cord-015369-72cjogxz 3776 1 The the DT cord-015369-72cjogxz 3776 2 aim aim NN cord-015369-72cjogxz 3776 3 of of IN cord-015369-72cjogxz 3776 4 this this DT cord-015369-72cjogxz 3776 5 study study NN cord-015369-72cjogxz 3776 6 was be VBD cord-015369-72cjogxz 3776 7 to to TO cord-015369-72cjogxz 3776 8 assess assess VB cord-015369-72cjogxz 3776 9 the the DT cord-015369-72cjogxz 3776 10 efficacy efficacy NN cord-015369-72cjogxz 3776 11 and and CC cord-015369-72cjogxz 3776 12 safety safety NN cord-015369-72cjogxz 3776 13 of of IN cord-015369-72cjogxz 3776 14 SAGB SAGB NNP cord-015369-72cjogxz 3776 15 in in IN cord-015369-72cjogxz 3776 16 older old JJR cord-015369-72cjogxz 3776 17 patients patient NNS cord-015369-72cjogxz 3776 18 aged age VBN cord-015369-72cjogxz 3776 19 ! ! . cord-015369-72cjogxz 3777 1 50 50 CD cord-015369-72cjogxz 3777 2 years year NNS cord-015369-72cjogxz 3777 3 . . . cord-015369-72cjogxz 3778 1 Methods method NNS cord-015369-72cjogxz 3778 2 . . . cord-015369-72cjogxz 3779 1 Between between IN cord-015369-72cjogxz 3779 2 01/1996 01/1996 CD cord-015369-72cjogxz 3779 3 and and CC cord-015369-72cjogxz 3779 4 01/2006 01/2006 CD cord-015369-72cjogxz 3779 5 , , , cord-015369-72cjogxz 3779 6 134 134 CD cord-015369-72cjogxz 3779 7 patients patient NNS cord-015369-72cjogxz 3779 8 were be VBD cord-015369-72cjogxz 3779 9 aged age VBN cord-015369-72cjogxz 3779 10 ! ! . cord-015369-72cjogxz 3780 1 50 50 CD cord-015369-72cjogxz 3780 2 years year NNS cord-015369-72cjogxz 3780 3 . . . cord-015369-72cjogxz 3781 1 Two two CD cord-015369-72cjogxz 3781 2 groups group NNS cord-015369-72cjogxz 3781 3 of of IN cord-015369-72cjogxz 3781 4 patients patient NNS cord-015369-72cjogxz 3781 5 were be VBD cord-015369-72cjogxz 3781 6 analyzed analyze VBN cord-015369-72cjogxz 3781 7 : : : cord-015369-72cjogxz 3781 8 Group group NN cord-015369-72cjogxz 3781 9 50 50 CD cord-015369-72cjogxz 3781 10 ( ( -LRB- cord-015369-72cjogxz 3781 11 n n NN cord-015369-72cjogxz 3781 12 ¼ ¼ NNP cord-015369-72cjogxz 3781 13 107 107 CD cord-015369-72cjogxz 3781 14 ) ) -RRB- cord-015369-72cjogxz 3781 15 patients patient NNS cord-015369-72cjogxz 3781 16 aged age VBN cord-015369-72cjogxz 3781 17 50 50 CD cord-015369-72cjogxz 3781 18 - - SYM cord-015369-72cjogxz 3781 19 59 59 CD cord-015369-72cjogxz 3781 20 years year NNS cord-015369-72cjogxz 3781 21 and and CC cord-015369-72cjogxz 3781 22 Group Group NNP cord-015369-72cjogxz 3781 23 60 60 CD cord-015369-72cjogxz 3781 24 ( ( -LRB- cord-015369-72cjogxz 3781 25 n n NN cord-015369-72cjogxz 3781 26 ¼ ¼ NNP cord-015369-72cjogxz 3781 27 27 27 CD cord-015369-72cjogxz 3781 28 ) ) -RRB- cord-015369-72cjogxz 3781 29 patients patient NNS cord-015369-72cjogxz 3781 30 aged age VBN cord-015369-72cjogxz 3781 31 60 60 CD cord-015369-72cjogxz 3781 32 - - SYM cord-015369-72cjogxz 3781 33 69 69 CD cord-015369-72cjogxz 3781 34 years year NNS cord-015369-72cjogxz 3781 35 . . . cord-015369-72cjogxz 3782 1 Results result NNS cord-015369-72cjogxz 3782 2 . . . cord-015369-72cjogxz 3783 1 One one CD cord-015369-72cjogxz 3783 2 hundred hundred CD cord-015369-72cjogxz 3783 3 and and CC cord-015369-72cjogxz 3783 4 thirty thirty CD cord-015369-72cjogxz 3783 5 - - HYPH cord-015369-72cjogxz 3783 6 four four CD cord-015369-72cjogxz 3783 7 patients patient NNS cord-015369-72cjogxz 3783 8 ( ( -LRB- cord-015369-72cjogxz 3783 9 17.1 17.1 CD cord-015369-72cjogxz 3783 10 % % NN cord-015369-72cjogxz 3783 11 ) ) -RRB- cord-015369-72cjogxz 3783 12 out out IN cord-015369-72cjogxz 3783 13 of of IN cord-015369-72cjogxz 3783 14 785 785 CD cord-015369-72cjogxz 3783 15 entered enter VBD cord-015369-72cjogxz 3783 16 the the DT cord-015369-72cjogxz 3783 17 study study NN cord-015369-72cjogxz 3783 18 . . . cord-015369-72cjogxz 3784 1 Mean mean JJ cord-015369-72cjogxz 3784 2 % % NN cord-015369-72cjogxz 3784 3 EWL EWL NNP cord-015369-72cjogxz 3784 4 was be VBD cord-015369-72cjogxz 3784 5 37.5 37.5 CD cord-015369-72cjogxz 3784 6 at at IN cord-015369-72cjogxz 3784 7 1 1 CD cord-015369-72cjogxz 3784 8 year year NN cord-015369-72cjogxz 3784 9 and and CC cord-015369-72cjogxz 3784 10 48.8 48.8 CD cord-015369-72cjogxz 3784 11 at at IN cord-015369-72cjogxz 3784 12 7 7 CD cord-015369-72cjogxz 3784 13 years year NNS cord-015369-72cjogxz 3784 14 , , , cord-015369-72cjogxz 3784 15 BMI BMI NNP cord-015369-72cjogxz 3784 16 fell fall VBD cord-015369-72cjogxz 3784 17 from from IN cord-015369-72cjogxz 3784 18 43.3 43.3 CD cord-015369-72cjogxz 3784 19 to to IN cord-015369-72cjogxz 3784 20 33.1 33.1 CD cord-015369-72cjogxz 3784 21 at at IN cord-015369-72cjogxz 3784 22 7 7 CD cord-015369-72cjogxz 3784 23 years year NNS cord-015369-72cjogxz 3784 24 . . . cord-015369-72cjogxz 3785 1 In in IN cord-015369-72cjogxz 3785 2 the the DT cord-015369-72cjogxz 3785 3 134 134 CD cord-015369-72cjogxz 3785 4 patients patient NNS cord-015369-72cjogxz 3785 5 , , , cord-015369-72cjogxz 3785 6 there there EX cord-015369-72cjogxz 3785 7 were be VBD cord-015369-72cjogxz 3785 8 65 65 CD cord-015369-72cjogxz 3785 9 patients patient NNS cord-015369-72cjogxz 3785 10 with with IN cord-015369-72cjogxz 3785 11 121 121 CD cord-015369-72cjogxz 3785 12 complications complication NNS cord-015369-72cjogxz 3785 13 ( ( -LRB- cord-015369-72cjogxz 3785 14 48.5 48.5 CD cord-015369-72cjogxz 3785 15 % % NN cord-015369-72cjogxz 3785 16 ) ) -RRB- cord-015369-72cjogxz 3785 17 and and CC cord-015369-72cjogxz 3785 18 69 69 CD cord-015369-72cjogxz 3785 19 patients patient NNS cord-015369-72cjogxz 3785 20 with with IN cord-015369-72cjogxz 3785 21 no no DT cord-015369-72cjogxz 3785 22 complication complication NN cord-015369-72cjogxz 3785 23 ( ( -LRB- cord-015369-72cjogxz 3785 24 51.5 51.5 CD cord-015369-72cjogxz 3785 25 % % NN cord-015369-72cjogxz 3785 26 ) ) -RRB- cord-015369-72cjogxz 3785 27 . . . cord-015369-72cjogxz 3786 1 The the DT cord-015369-72cjogxz 3786 2 most most RBS cord-015369-72cjogxz 3786 3 common common JJ cord-015369-72cjogxz 3786 4 complications complication NNS cord-015369-72cjogxz 3786 5 were be VBD cord-015369-72cjogxz 3786 6 esophagitis esophagitis JJ cord-015369-72cjogxz 3786 7 , , , cord-015369-72cjogxz 3786 8 esophageal esophageal JJ cord-015369-72cjogxz 3786 9 dilation dilation NN cord-015369-72cjogxz 3786 10 , , , cord-015369-72cjogxz 3786 11 port port NN cord-015369-72cjogxz 3786 12 problems problem NNS cord-015369-72cjogxz 3786 13 and and CC cord-015369-72cjogxz 3786 14 pouch pouch NN cord-015369-72cjogxz 3786 15 dilation dilation NN cord-015369-72cjogxz 3786 16 . . . cord-015369-72cjogxz 3787 1 In in IN cord-015369-72cjogxz 3787 2 Group Group NNP cord-015369-72cjogxz 3787 3 50 50 CD cord-015369-72cjogxz 3787 4 , , , cord-015369-72cjogxz 3787 5 mean mean VBP cord-015369-72cjogxz 3787 6 % % NN cord-015369-72cjogxz 3787 7 EWL EWL NNP cord-015369-72cjogxz 3787 8 was be VBD cord-015369-72cjogxz 3787 9 38.4 38.4 CD cord-015369-72cjogxz 3787 10 at at IN cord-015369-72cjogxz 3787 11 1 1 CD cord-015369-72cjogxz 3787 12 year year NN cord-015369-72cjogxz 3787 13 and and CC cord-015369-72cjogxz 3787 14 54.9 54.9 CD cord-015369-72cjogxz 3787 15 at at IN cord-015369-72cjogxz 3787 16 7 7 CD cord-015369-72cjogxz 3787 17 years year NNS cord-015369-72cjogxz 3787 18 . . . cord-015369-72cjogxz 3788 1 BMI BMI NNP cord-015369-72cjogxz 3788 2 fell fall VBD cord-015369-72cjogxz 3788 3 from from IN cord-015369-72cjogxz 3788 4 42.9 42.9 CD cord-015369-72cjogxz 3788 5 to to IN cord-015369-72cjogxz 3788 6 33.1 33.1 CD cord-015369-72cjogxz 3788 7 at at IN cord-015369-72cjogxz 3788 8 7 7 CD cord-015369-72cjogxz 3788 9 years year NNS cord-015369-72cjogxz 3788 10 . . . cord-015369-72cjogxz 3789 1 In in IN cord-015369-72cjogxz 3789 2 the the DT cord-015369-72cjogxz 3789 3 107 107 CD cord-015369-72cjogxz 3789 4 patients patient NNS cord-015369-72cjogxz 3789 5 , , , cord-015369-72cjogxz 3789 6 there there EX cord-015369-72cjogxz 3789 7 were be VBD cord-015369-72cjogxz 3789 8 55 55 CD cord-015369-72cjogxz 3789 9 patients patient NNS cord-015369-72cjogxz 3789 10 with with IN cord-015369-72cjogxz 3789 11 99 99 CD cord-015369-72cjogxz 3789 12 complications complication NNS cord-015369-72cjogxz 3789 13 ( ( -LRB- cord-015369-72cjogxz 3789 14 51 51 CD cord-015369-72cjogxz 3789 15 % % NN cord-015369-72cjogxz 3789 16 ) ) -RRB- cord-015369-72cjogxz 3789 17 and and CC cord-015369-72cjogxz 3789 18 a a DT cord-015369-72cjogxz 3789 19 reoperation reoperation NN cord-015369-72cjogxz 3789 20 rate rate NN cord-015369-72cjogxz 3789 21 of of IN cord-015369-72cjogxz 3789 22 35.5 35.5 CD cord-015369-72cjogxz 3789 23 % % NN cord-015369-72cjogxz 3789 24 . . . cord-015369-72cjogxz 3790 1 In in IN cord-015369-72cjogxz 3790 2 Group Group NNP cord-015369-72cjogxz 3790 3 60 60 CD cord-015369-72cjogxz 3790 4 , , , cord-015369-72cjogxz 3790 5 mean mean JJ cord-015369-72cjogxz 3790 6 % % NN cord-015369-72cjogxz 3790 7 EWL EWL NNP cord-015369-72cjogxz 3790 8 was be VBD cord-015369-72cjogxz 3790 9 32.8 32.8 CD cord-015369-72cjogxz 3790 10 at at IN cord-015369-72cjogxz 3790 11 1 1 CD cord-015369-72cjogxz 3790 12 year year NN cord-015369-72cjogxz 3790 13 and and CC cord-015369-72cjogxz 3790 14 41.2 41.2 CD cord-015369-72cjogxz 3790 15 at at IN cord-015369-72cjogxz 3790 16 7 7 CD cord-015369-72cjogxz 3790 17 years year NNS cord-015369-72cjogxz 3790 18 . . . cord-015369-72cjogxz 3791 1 BMI BMI NNP cord-015369-72cjogxz 3791 2 fell fall VBD cord-015369-72cjogxz 3791 3 from from IN cord-015369-72cjogxz 3791 4 44.3 44.3 CD cord-015369-72cjogxz 3791 5 to to IN cord-015369-72cjogxz 3791 6 34 34 CD cord-015369-72cjogxz 3791 7 at at IN cord-015369-72cjogxz 3791 8 7 7 CD cord-015369-72cjogxz 3791 9 years year NNS cord-015369-72cjogxz 3791 10 . . . cord-015369-72cjogxz 3792 1 In in IN cord-015369-72cjogxz 3792 2 the the DT cord-015369-72cjogxz 3792 3 27 27 CD cord-015369-72cjogxz 3792 4 patients patient NNS cord-015369-72cjogxz 3792 5 , , , cord-015369-72cjogxz 3792 6 there there EX cord-015369-72cjogxz 3792 7 were be VBD cord-015369-72cjogxz 3792 8 ten ten CD cord-015369-72cjogxz 3792 9 patients patient NNS cord-015369-72cjogxz 3792 10 with with IN cord-015369-72cjogxz 3792 11 22 22 CD cord-015369-72cjogxz 3792 12 complications complication NNS cord-015369-72cjogxz 3792 13 ( ( -LRB- cord-015369-72cjogxz 3792 14 37 37 CD cord-015369-72cjogxz 3792 15 % % NN cord-015369-72cjogxz 3792 16 ) ) -RRB- cord-015369-72cjogxz 3792 17 and and CC cord-015369-72cjogxz 3792 18 a a DT cord-015369-72cjogxz 3792 19 reoperation reoperation NN cord-015369-72cjogxz 3792 20 rate rate NN cord-015369-72cjogxz 3792 21 of of IN cord-015369-72cjogxz 3792 22 29.6 29.6 CD cord-015369-72cjogxz 3792 23 % % NN cord-015369-72cjogxz 3792 24 . . . cord-015369-72cjogxz 3793 1 There there EX cord-015369-72cjogxz 3793 2 was be VBD cord-015369-72cjogxz 3793 3 no no DT cord-015369-72cjogxz 3793 4 mortality mortality NN cord-015369-72cjogxz 3793 5 . . . cord-015369-72cjogxz 3794 1 Conclusions conclusion NNS cord-015369-72cjogxz 3794 2 . . . cord-015369-72cjogxz 3795 1 At at IN cord-015369-72cjogxz 3795 2 7-year 7-year CD cord-015369-72cjogxz 3795 3 follow follow NN cord-015369-72cjogxz 3795 4 - - HYPH cord-015369-72cjogxz 3795 5 up up NN cord-015369-72cjogxz 3795 6 , , , cord-015369-72cjogxz 3795 7 for for IN cord-015369-72cjogxz 3795 8 older old JJR cord-015369-72cjogxz 3795 9 patients patient NNS cord-015369-72cjogxz 3795 10 , , , cord-015369-72cjogxz 3795 11 SAGB SAGB NNP cord-015369-72cjogxz 3795 12 is be VBZ cord-015369-72cjogxz 3795 13 an an DT cord-015369-72cjogxz 3795 14 effective effective JJ cord-015369-72cjogxz 3795 15 bariatric bariatric JJ cord-015369-72cjogxz 3795 16 procedure procedure NN cord-015369-72cjogxz 3795 17 for for IN cord-015369-72cjogxz 3795 18 achieving achieve VBG cord-015369-72cjogxz 3795 19 weight weight NN cord-015369-72cjogxz 3795 20 loss loss NN cord-015369-72cjogxz 3795 21 . . . cord-015369-72cjogxz 3796 1 Nevertheless nevertheless RB cord-015369-72cjogxz 3796 2 , , , cord-015369-72cjogxz 3796 3 based base VBN cord-015369-72cjogxz 3796 4 on on IN cord-015369-72cjogxz 3796 5 the the DT cord-015369-72cjogxz 3796 6 high high JJ cord-015369-72cjogxz 3796 7 complication complication NN cord-015369-72cjogxz 3796 8 and and CC cord-015369-72cjogxz 3796 9 reoperation reoperation NN cord-015369-72cjogxz 3796 10 rate rate NN cord-015369-72cjogxz 3796 11 , , , cord-015369-72cjogxz 3796 12 a a DT cord-015369-72cjogxz 3796 13 gastric gastric JJ cord-015369-72cjogxz 3796 14 band band NN cord-015369-72cjogxz 3796 15 - - HYPH cord-015369-72cjogxz 3796 16 specific specific JJ cord-015369-72cjogxz 3796 17 patient patient NN cord-015369-72cjogxz 3796 18 selection selection NN cord-015369-72cjogxz 3796 19 will will MD cord-015369-72cjogxz 3796 20 be be VB cord-015369-72cjogxz 3796 21 necessary necessary JJ cord-015369-72cjogxz 3796 22 . . . cord-015369-72cjogxz 3797 1 Background background NN cord-015369-72cjogxz 3797 2 . . . cord-015369-72cjogxz 3798 1 Study study NN cord-015369-72cjogxz 3798 2 aim aim NN cord-015369-72cjogxz 3798 3 was be VBD cord-015369-72cjogxz 3798 4 to to TO cord-015369-72cjogxz 3798 5 retrospectively retrospectively RB cord-015369-72cjogxz 3798 6 assess assess VB cord-015369-72cjogxz 3798 7 whether whether IN cord-015369-72cjogxz 3798 8 patients patient NNS cord-015369-72cjogxz 3798 9 were be VBD cord-015369-72cjogxz 3798 10 able able JJ cord-015369-72cjogxz 3798 11 to to TO cord-015369-72cjogxz 3798 12 maintain maintain VB cord-015369-72cjogxz 3798 13 their -PRON- PRP$ cord-015369-72cjogxz 3798 14 weight weight NN cord-015369-72cjogxz 3798 15 after after IN cord-015369-72cjogxz 3798 16 gastric gastric JJ cord-015369-72cjogxz 3798 17 band band NN cord-015369-72cjogxz 3798 18 removal removal NN cord-015369-72cjogxz 3798 19 or or CC cord-015369-72cjogxz 3798 20 deflation deflation NN cord-015369-72cjogxz 3798 21 and and CC cord-015369-72cjogxz 3798 22 how how WRB cord-015369-72cjogxz 3798 23 they -PRON- PRP cord-015369-72cjogxz 3798 24 felt feel VBD cord-015369-72cjogxz 3798 25 about about IN cord-015369-72cjogxz 3798 26 gastric gastric JJ cord-015369-72cjogxz 3798 27 banding banding NN cord-015369-72cjogxz 3798 28 . . . cord-015369-72cjogxz 3799 1 Methods method NNS cord-015369-72cjogxz 3799 2 . . . cord-015369-72cjogxz 3800 1 Total total JJ cord-015369-72cjogxz 3800 2 41 41 CD cord-015369-72cjogxz 3800 3 patients patient NNS cord-015369-72cjogxz 3800 4 ( ( -LRB- cord-015369-72cjogxz 3800 5 93 93 CD cord-015369-72cjogxz 3800 6 % % NN cord-015369-72cjogxz 3800 7 female female NN cord-015369-72cjogxz 3800 8 , , , cord-015369-72cjogxz 3800 9 mean mean VB cord-015369-72cjogxz 3800 10 age age NN cord-015369-72cjogxz 3800 11 34.1 34.1 CD cord-015369-72cjogxz 3800 12 ( ( -LRB- cord-015369-72cjogxz 3800 13 SD SD NNP cord-015369-72cjogxz 3800 14 10.5 10.5 CD cord-015369-72cjogxz 3800 15 ) ) -RRB- cord-015369-72cjogxz 3800 16 years year NNS cord-015369-72cjogxz 3800 17 ) ) -RRB- cord-015369-72cjogxz 3800 18 were be VBD cord-015369-72cjogxz 3800 19 included include VBN cord-015369-72cjogxz 3800 20 in in IN cord-015369-72cjogxz 3800 21 this this DT cord-015369-72cjogxz 3800 22 study study NN cord-015369-72cjogxz 3800 23 : : : cord-015369-72cjogxz 3800 24 patients patient NNS cord-015369-72cjogxz 3800 25 who who WP cord-015369-72cjogxz 3800 26 had have VBD cord-015369-72cjogxz 3800 27 their -PRON- PRP$ cord-015369-72cjogxz 3800 28 band band NN cord-015369-72cjogxz 3800 29 removed remove VBN cord-015369-72cjogxz 3800 30 / / SYM cord-015369-72cjogxz 3800 31 deflated deflate VBD cord-015369-72cjogxz 3800 32 without without IN cord-015369-72cjogxz 3800 33 further further JJ cord-015369-72cjogxz 3800 34 surgical surgical JJ cord-015369-72cjogxz 3800 35 intervention intervention NN cord-015369-72cjogxz 3800 36 ( ( -LRB- cord-015369-72cjogxz 3800 37 Group Group NNP cord-015369-72cjogxz 3800 38 1 1 CD cord-015369-72cjogxz 3800 39 , , , cord-015369-72cjogxz 3800 40 n n NN cord-015369-72cjogxz 3800 41 ¼ ¼ NNP cord-015369-72cjogxz 3800 42 26 26 CD cord-015369-72cjogxz 3800 43 ) ) -RRB- cord-015369-72cjogxz 3800 44 , , , cord-015369-72cjogxz 3800 45 those those DT cord-015369-72cjogxz 3800 46 who who WP cord-015369-72cjogxz 3800 47 later later RB cord-015369-72cjogxz 3800 48 underwent undergo VBD cord-015369-72cjogxz 3800 49 a a DT cord-015369-72cjogxz 3800 50 second second JJ cord-015369-72cjogxz 3800 51 bariatric bariatric JJ cord-015369-72cjogxz 3800 52 operation operation NN cord-015369-72cjogxz 3800 53 ( ( -LRB- cord-015369-72cjogxz 3800 54 Group Group NNP cord-015369-72cjogxz 3800 55 2 2 CD cord-015369-72cjogxz 3800 56 , , , cord-015369-72cjogxz 3800 57 n n NN cord-015369-72cjogxz 3800 58 ¼ ¼ NNP cord-015369-72cjogxz 3800 59 15 15 CD cord-015369-72cjogxz 3800 60 ) ) -RRB- cord-015369-72cjogxz 3800 61 . . . cord-015369-72cjogxz 3801 1 We -PRON- PRP cord-015369-72cjogxz 3801 2 evaluated evaluate VBD cord-015369-72cjogxz 3801 3 weight weight NN cord-015369-72cjogxz 3801 4 gain gain NN cord-015369-72cjogxz 3801 5 after after IN cord-015369-72cjogxz 3801 6 band band NN cord-015369-72cjogxz 3801 7 removal removal NN cord-015369-72cjogxz 3801 8 / / , cord-015369-72cjogxz 3801 9 during during IN cord-015369-72cjogxz 3801 10 the the DT cord-015369-72cjogxz 3801 11 time time NN cord-015369-72cjogxz 3801 12 between between IN cord-015369-72cjogxz 3801 13 band band NN cord-015369-72cjogxz 3801 14 removal removal NN cord-015369-72cjogxz 3801 15 and and CC cord-015369-72cjogxz 3801 16 second second JJ cord-015369-72cjogxz 3801 17 bariatric bariatric JJ cord-015369-72cjogxz 3801 18 operation operation NN cord-015369-72cjogxz 3801 19 . . . cord-015369-72cjogxz 3802 1 Results result NNS cord-015369-72cjogxz 3802 2 . . . cord-015369-72cjogxz 3803 1 Of of IN cord-015369-72cjogxz 3803 2 our -PRON- PRP$ cord-015369-72cjogxz 3803 3 patients patient NNS cord-015369-72cjogxz 3803 4 31 31 CD cord-015369-72cjogxz 3803 5 ( ( -LRB- cord-015369-72cjogxz 3803 6 76 76 CD cord-015369-72cjogxz 3803 7 % % NN cord-015369-72cjogxz 3803 8 ) ) -RRB- cord-015369-72cjogxz 3803 9 suffered suffer VBD cord-015369-72cjogxz 3803 10 a a DT cord-015369-72cjogxz 3803 11 complication complication NN cord-015369-72cjogxz 3803 12 ( ( -LRB- cord-015369-72cjogxz 3803 13 18 18 CD cord-015369-72cjogxz 3803 14 late late JJ cord-015369-72cjogxz 3803 15 pouch pouch NN cord-015369-72cjogxz 3803 16 dilatations dilatation NNS cord-015369-72cjogxz 3803 17 , , , cord-015369-72cjogxz 3803 18 six six CD cord-015369-72cjogxz 3803 19 band band NN cord-015369-72cjogxz 3803 20 infections infection NNS cord-015369-72cjogxz 3803 21 , , , cord-015369-72cjogxz 3803 22 five five CD cord-015369-72cjogxz 3803 23 band band NN cord-015369-72cjogxz 3803 24 migrations migration NNS cord-015369-72cjogxz 3803 25 , , , cord-015369-72cjogxz 3803 26 two two CD cord-015369-72cjogxz 3803 27 band band NN cord-015369-72cjogxz 3803 28 leaks leak NNS cord-015369-72cjogxz 3803 29 ) ) -RRB- cord-015369-72cjogxz 3803 30 requiring require VBG cord-015369-72cjogxz 3803 31 band band NN cord-015369-72cjogxz 3803 32 removal removal NN cord-015369-72cjogxz 3803 33 . . . cord-015369-72cjogxz 3804 1 Ten ten CD cord-015369-72cjogxz 3804 2 patients patient NNS cord-015369-72cjogxz 3804 3 wanted want VBD cord-015369-72cjogxz 3804 4 their -PRON- PRP$ cord-015369-72cjogxz 3804 5 band band NN cord-015369-72cjogxz 3804 6 removed remove VBN cord-015369-72cjogxz 3804 7 ( ( -LRB- cord-015369-72cjogxz 3804 8 six six CD cord-015369-72cjogxz 3804 9 ) ) -RRB- cord-015369-72cjogxz 3804 10 or or CC cord-015369-72cjogxz 3804 11 emptied empty VBN cord-015369-72cjogxz 3804 12 ( ( -LRB- cord-015369-72cjogxz 3804 13 four four CD cord-015369-72cjogxz 3804 14 ) ) -RRB- cord-015369-72cjogxz 3804 15 . . . cord-015369-72cjogxz 3805 1 Mean mean JJ cord-015369-72cjogxz 3805 2 time time NN cord-015369-72cjogxz 3805 3 after after IN cord-015369-72cjogxz 3805 4 band band NN cord-015369-72cjogxz 3805 5 removal removal NN cord-015369-72cjogxz 3805 6 , , , cord-015369-72cjogxz 3805 7 when when WRB cord-015369-72cjogxz 3805 8 patients patient NNS cord-015369-72cjogxz 3805 9 had have VBD cord-015369-72cjogxz 3805 10 neither neither CC cord-015369-72cjogxz 3805 11 a a DT cord-015369-72cjogxz 3805 12 band band NN cord-015369-72cjogxz 3805 13 nor nor CC cord-015369-72cjogxz 3805 14 a a DT cord-015369-72cjogxz 3805 15 second second JJ cord-015369-72cjogxz 3805 16 bariatric bariatric JJ cord-015369-72cjogxz 3805 17 operation operation NN cord-015369-72cjogxz 3805 18 , , , cord-015369-72cjogxz 3805 19 was be VBD cord-015369-72cjogxz 3805 20 2.84 2.84 CD cord-015369-72cjogxz 3805 21 ( ( -LRB- cord-015369-72cjogxz 3805 22 SD SD NNP cord-015369-72cjogxz 3805 23 2.3 2.3 CD cord-015369-72cjogxz 3805 24 ) ) -RRB- cord-015369-72cjogxz 3805 25 years year NNS cord-015369-72cjogxz 3805 26 . . . cord-015369-72cjogxz 3806 1 Five five CD cord-015369-72cjogxz 3806 2 ( ( -LRB- cord-015369-72cjogxz 3806 3 12.2 12.2 CD cord-015369-72cjogxz 3806 4 % % NN cord-015369-72cjogxz 3806 5 ) ) -RRB- cord-015369-72cjogxz 3807 1 patients patient NNS cord-015369-72cjogxz 3807 2 maintained maintain VBD cord-015369-72cjogxz 3807 3 their -PRON- PRP$ cord-015369-72cjogxz 3807 4 weight weight NN cord-015369-72cjogxz 3807 5 , , , cord-015369-72cjogxz 3807 6 four four CD cord-015369-72cjogxz 3807 7 of of IN cord-015369-72cjogxz 3807 8 whom whom WP cord-015369-72cjogxz 3807 9 experienced experience VBD cord-015369-72cjogxz 3807 10 a a DT cord-015369-72cjogxz 3807 11 learning learning NN cord-015369-72cjogxz 3807 12 effect effect NN cord-015369-72cjogxz 3807 13 , , , cord-015369-72cjogxz 3807 14 all all DT cord-015369-72cjogxz 3807 15 others other NNS cord-015369-72cjogxz 3807 16 gained gain VBD cord-015369-72cjogxz 3807 17 weight weight NN cord-015369-72cjogxz 3807 18 . . . cord-015369-72cjogxz 3808 1 Mean mean JJ cord-015369-72cjogxz 3808 2 BMI BMI NNP cord-015369-72cjogxz 3808 3 for for IN cord-015369-72cjogxz 3808 4 both both DT cord-015369-72cjogxz 3808 5 groups group NNS cord-015369-72cjogxz 3808 6 after after IN cord-015369-72cjogxz 3808 7 the the DT cord-015369-72cjogxz 3808 8 period period NN cord-015369-72cjogxz 3808 9 without without IN cord-015369-72cjogxz 3808 10 a a DT cord-015369-72cjogxz 3808 11 band band NN cord-015369-72cjogxz 3808 12 was be VBD cord-015369-72cjogxz 3808 13 36.7 36.7 CD cord-015369-72cjogxz 3808 14 ( ( -LRB- cord-015369-72cjogxz 3808 15 SD SD NNP cord-015369-72cjogxz 3808 16 8.0 8.0 CD cord-015369-72cjogxz 3808 17 ) ) -RRB- cord-015369-72cjogxz 3808 18 kg kg NN cord-015369-72cjogxz 3808 19 / / SYM cord-015369-72cjogxz 3808 20 m m NN cord-015369-72cjogxz 3808 21 2 2 CD cord-015369-72cjogxz 3808 22 ( ( -LRB- cord-015369-72cjogxz 3808 23 vs. vs. NN cord-015369-72cjogxz 3808 24 29.4 29.4 CD cord-015369-72cjogxz 3808 25 ( ( -LRB- cord-015369-72cjogxz 3808 26 SD SD NNP cord-015369-72cjogxz 3808 27 7.0 7.0 CD cord-015369-72cjogxz 3808 28 ) ) -RRB- cord-015369-72cjogxz 3808 29 at at IN cord-015369-72cjogxz 3808 30 removal removal NN cord-015369-72cjogxz 3808 31 ) ) -RRB- cord-015369-72cjogxz 3808 32 and and CC cord-015369-72cjogxz 3808 33 excess excess JJ cord-015369-72cjogxz 3808 34 weight weight NN cord-015369-72cjogxz 3808 35 loss loss NN cord-015369-72cjogxz 3808 36 ( ( -LRB- cord-015369-72cjogxz 3808 37 EWL EWL NNP cord-015369-72cjogxz 3808 38 ) ) -RRB- cord-015369-72cjogxz 3808 39 was be VBD cord-015369-72cjogxz 3808 40 33.2 33.2 CD cord-015369-72cjogxz 3808 41 ( ( -LRB- cord-015369-72cjogxz 3808 42 SD SD NNP cord-015369-72cjogxz 3808 43 39.2 39.2 CD cord-015369-72cjogxz 3808 44 ) ) -RRB- cord-015369-72cjogxz 3808 45 % % NN cord-015369-72cjogxz 3808 46 ( ( -LRB- cord-015369-72cjogxz 3808 47 vs. vs. FW cord-015369-72cjogxz 3808 48 69.8 69.8 CD cord-015369-72cjogxz 3808 49 ( ( -LRB- cord-015369-72cjogxz 3808 50 SD SD NNP cord-015369-72cjogxz 3808 51 32.9 32.9 CD cord-015369-72cjogxz 3808 52 ) ) -RRB- cord-015369-72cjogxz 3808 53 % % NN cord-015369-72cjogxz 3808 54 at at IN cord-015369-72cjogxz 3808 55 removal removal NN cord-015369-72cjogxz 3808 56 ) ) -RRB- cord-015369-72cjogxz 3808 57 . . . cord-015369-72cjogxz 3809 1 Of of IN cord-015369-72cjogxz 3809 2 our -PRON- PRP$ cord-015369-72cjogxz 3809 3 patients patient NNS cord-015369-72cjogxz 3809 4 73 73 CD cord-015369-72cjogxz 3809 5 % % NN cord-015369-72cjogxz 3809 6 stated state VBD cord-015369-72cjogxz 3809 7 they -PRON- PRP cord-015369-72cjogxz 3809 8 would would MD cord-015369-72cjogxz 3809 9 not not RB cord-015369-72cjogxz 3809 10 agree agree VB cord-015369-72cjogxz 3809 11 to to IN cord-015369-72cjogxz 3809 12 gastric gastric JJ cord-015369-72cjogxz 3809 13 banding banding NN cord-015369-72cjogxz 3809 14 again again RB cord-015369-72cjogxz 3809 15 . . . cord-015369-72cjogxz 3810 1 According accord VBG cord-015369-72cjogxz 3810 2 to to IN cord-015369-72cjogxz 3810 3 BAROS BAROS NNP cord-015369-72cjogxz 3810 4 , , , cord-015369-72cjogxz 3810 5 long long JJ cord-015369-72cjogxz 3810 6 - - HYPH cord-015369-72cjogxz 3810 7 term term NN cord-015369-72cjogxz 3810 8 outcome outcome NN cord-015369-72cjogxz 3810 9 of of IN cord-015369-72cjogxz 3810 10 patients patient NNS cord-015369-72cjogxz 3810 11 following follow VBG cord-015369-72cjogxz 3810 12 band band NN cord-015369-72cjogxz 3810 13 removal removal NN cord-015369-72cjogxz 3810 14 was be VBD cord-015369-72cjogxz 3810 15 a a DT cord-015369-72cjogxz 3810 16 ' ' '' cord-015369-72cjogxz 3810 17 ' ' `` cord-015369-72cjogxz 3810 18 failure failure NN cord-015369-72cjogxz 3810 19 ' ' '' cord-015369-72cjogxz 3810 20 ' ' '' cord-015369-72cjogxz 3810 21 in in IN cord-015369-72cjogxz 3810 22 66 66 CD cord-015369-72cjogxz 3810 23 % % NN cord-015369-72cjogxz 3810 24 of of IN cord-015369-72cjogxz 3810 25 patients patient NNS cord-015369-72cjogxz 3810 26 . . . cord-015369-72cjogxz 3811 1 Conclusions conclusion NNS cord-015369-72cjogxz 3811 2 . . . cord-015369-72cjogxz 3812 1 Long long JJ cord-015369-72cjogxz 3812 2 - - HYPH cord-015369-72cjogxz 3812 3 term term NN cord-015369-72cjogxz 3812 4 outcome outcome NN cord-015369-72cjogxz 3812 5 following follow VBG cord-015369-72cjogxz 3812 6 band band NN cord-015369-72cjogxz 3812 7 removal removal NN cord-015369-72cjogxz 3812 8 is be VBZ cord-015369-72cjogxz 3812 9 unsatisfactory unsatisfactory JJ cord-015369-72cjogxz 3812 10 in in IN cord-015369-72cjogxz 3812 11 many many JJ cord-015369-72cjogxz 3812 12 patients patient NNS cord-015369-72cjogxz 3812 13 . . . cord-015369-72cjogxz 3813 1 Nevertheless nevertheless RB cord-015369-72cjogxz 3813 2 , , , cord-015369-72cjogxz 3813 3 a a DT cord-015369-72cjogxz 3813 4 minority minority NN cord-015369-72cjogxz 3813 5 of of IN cord-015369-72cjogxz 3813 6 patients patient NNS cord-015369-72cjogxz 3813 7 was be VBD cord-015369-72cjogxz 3813 8 able able JJ cord-015369-72cjogxz 3813 9 to to TO cord-015369-72cjogxz 3813 10 maintain maintain VB cord-015369-72cjogxz 3813 11 its -PRON- PRP$ cord-015369-72cjogxz 3813 12 weight weight NN cord-015369-72cjogxz 3813 13 loss loss NN cord-015369-72cjogxz 3813 14 . . . cord-015369-72cjogxz 3814 1 Background background NN cord-015369-72cjogxz 3814 2 . . . cord-015369-72cjogxz 3815 1 In in IN cord-015369-72cjogxz 3815 2 bariatric bariatric JJ cord-015369-72cjogxz 3815 3 surgery surgery NN cord-015369-72cjogxz 3815 4 studies study NNS cord-015369-72cjogxz 3815 5 show show VBP cord-015369-72cjogxz 3815 6 that that IN cord-015369-72cjogxz 3815 7 a a DT cord-015369-72cjogxz 3815 8 better well JJR cord-015369-72cjogxz 3815 9 quality quality NN cord-015369-72cjogxz 3815 10 of of IN cord-015369-72cjogxz 3815 11 life life NN cord-015369-72cjogxz 3815 12 is be VBZ cord-015369-72cjogxz 3815 13 correlated correlate VBN cord-015369-72cjogxz 3815 14 to to IN cord-015369-72cjogxz 3815 15 increased increase VBN cord-015369-72cjogxz 3815 16 weight weight NN cord-015369-72cjogxz 3815 17 loss loss NN cord-015369-72cjogxz 3815 18 . . . cord-015369-72cjogxz 3816 1 The the DT cord-015369-72cjogxz 3816 2 question question NN cord-015369-72cjogxz 3816 3 remained remain VBD cord-015369-72cjogxz 3816 4 which which WDT cord-015369-72cjogxz 3816 5 type type NN cord-015369-72cjogxz 3816 6 of of IN cord-015369-72cjogxz 3816 7 surgery surgery NN cord-015369-72cjogxz 3816 8 is be VBZ cord-015369-72cjogxz 3816 9 superior superior JJ cord-015369-72cjogxz 3816 10 in in IN cord-015369-72cjogxz 3816 11 quality quality NN cord-015369-72cjogxz 3816 12 of of IN cord-015369-72cjogxz 3816 13 life life NN cord-015369-72cjogxz 3816 14 independently independently RB cord-015369-72cjogxz 3816 15 from from IN cord-015369-72cjogxz 3816 16 weight weight NN cord-015369-72cjogxz 3816 17 loss loss NN cord-015369-72cjogxz 3816 18 . . . cord-015369-72cjogxz 3817 1 Methods method NNS cord-015369-72cjogxz 3817 2 . . . cord-015369-72cjogxz 3818 1 In in IN cord-015369-72cjogxz 3818 2 our -PRON- PRP$ cord-015369-72cjogxz 3818 3 study study NN cord-015369-72cjogxz 3818 4 we -PRON- PRP cord-015369-72cjogxz 3818 5 recruited recruit VBD cord-015369-72cjogxz 3818 6 250 250 CD cord-015369-72cjogxz 3818 7 bariatric bariatric JJ cord-015369-72cjogxz 3818 8 patients patient NNS cord-015369-72cjogxz 3818 9 , , , cord-015369-72cjogxz 3818 10 operated operate VBN cord-015369-72cjogxz 3818 11 between between IN cord-015369-72cjogxz 3818 12 2003 2003 CD cord-015369-72cjogxz 3818 13 and and CC cord-015369-72cjogxz 3818 14 2005 2005 CD cord-015369-72cjogxz 3818 15 ( ( -LRB- cord-015369-72cjogxz 3818 16 196 196 CD cord-015369-72cjogxz 3818 17 women/54 women/54 CD cord-015369-72cjogxz 3818 18 men man NNS cord-015369-72cjogxz 3818 19 ) ) -RRB- cord-015369-72cjogxz 3818 20 at at IN cord-015369-72cjogxz 3818 21 the the DT cord-015369-72cjogxz 3818 22 mean mean JJ cord-015369-72cjogxz 3818 23 age age NN cord-015369-72cjogxz 3818 24 of of IN cord-015369-72cjogxz 3818 25 39.85 39.85 CD cord-015369-72cjogxz 3818 26 years year NNS cord-015369-72cjogxz 3818 27 ( ( -LRB- cord-015369-72cjogxz 3818 28 SD SD NNP cord-015369-72cjogxz 3818 29 ¼ ¼ NNP cord-015369-72cjogxz 3818 30 11.65 11.65 CD cord-015369-72cjogxz 3818 31 ) ) -RRB- cord-015369-72cjogxz 3818 32 and and CC cord-015369-72cjogxz 3818 33 with with IN cord-015369-72cjogxz 3818 34 a a DT cord-015369-72cjogxz 3818 35 mean mean JJ cord-015369-72cjogxz 3818 36 BMI bmi NN cord-015369-72cjogxz 3818 37 of of IN cord-015369-72cjogxz 3818 38 44.78 44.78 CD cord-015369-72cjogxz 3818 39 kg kg NNP cord-015369-72cjogxz 3818 40 / / SYM cord-015369-72cjogxz 3818 41 m m NN cord-015369-72cjogxz 3818 42 2 2 CD cord-015369-72cjogxz 3819 1 ( ( -LRB- cord-015369-72cjogxz 3819 2 SD SD NNP cord-015369-72cjogxz 3819 3 ¼ ¼ NNP cord-015369-72cjogxz 3819 4 7.04 7.04 CD cord-015369-72cjogxz 3819 5 ) ) -RRB- cord-015369-72cjogxz 3819 6 . . . cord-015369-72cjogxz 3820 1 Patients patient NNS cord-015369-72cjogxz 3820 2 eligible eligible JJ cord-015369-72cjogxz 3820 3 for for IN cord-015369-72cjogxz 3820 4 investigation investigation NN cord-015369-72cjogxz 3820 5 were be VBD cord-015369-72cjogxz 3820 6 78 78 CD cord-015369-72cjogxz 3820 7 Patients patient NNS cord-015369-72cjogxz 3820 8 with with IN cord-015369-72cjogxz 3820 9 Laparoscopic Laparoscopic NNP cord-015369-72cjogxz 3820 10 Gastric Gastric NNP cord-015369-72cjogxz 3820 11 Bypass Bypass NNP cord-015369-72cjogxz 3820 12 and and CC cord-015369-72cjogxz 3820 13 172 172 CD cord-015369-72cjogxz 3820 14 Patients patient NNS cord-015369-72cjogxz 3820 15 with with IN cord-015369-72cjogxz 3820 16 Adjustable adjustable JJ cord-015369-72cjogxz 3820 17 Gastric gastric JJ cord-015369-72cjogxz 3820 18 Banding banding NN cord-015369-72cjogxz 3820 19 ( ( -LRB- cord-015369-72cjogxz 3820 20 AGB AGB NNP cord-015369-72cjogxz 3820 21 ) ) -RRB- cord-015369-72cjogxz 3820 22 . . . cord-015369-72cjogxz 3821 1 The the DT cord-015369-72cjogxz 3821 2 patients patient NNS cord-015369-72cjogxz 3821 3 were be VBD cord-015369-72cjogxz 3821 4 reviewed review VBN cord-015369-72cjogxz 3821 5 in in IN cord-015369-72cjogxz 3821 6 the the DT cord-015369-72cjogxz 3821 7 interval interval NN cord-015369-72cjogxz 3821 8 of of IN cord-015369-72cjogxz 3821 9 3 3 CD cord-015369-72cjogxz 3821 10 , , , cord-015369-72cjogxz 3821 11 6 6 CD cord-015369-72cjogxz 3821 12 , , , cord-015369-72cjogxz 3821 13 12 12 CD cord-015369-72cjogxz 3821 14 , , , cord-015369-72cjogxz 3821 15 24 24 CD cord-015369-72cjogxz 3821 16 , , , cord-015369-72cjogxz 3821 17 36 36 CD cord-015369-72cjogxz 3821 18 , , , cord-015369-72cjogxz 3821 19 48 48 CD cord-015369-72cjogxz 3821 20 and and CC cord-015369-72cjogxz 3821 21 63 63 CD cord-015369-72cjogxz 3821 22 months month NNS cord-015369-72cjogxz 3821 23 after after IN cord-015369-72cjogxz 3821 24 operation operation NN cord-015369-72cjogxz 3821 25 . . . cord-015369-72cjogxz 3822 1 The the DT cord-015369-72cjogxz 3822 2 Bariatric Bariatric NNP cord-015369-72cjogxz 3822 3 Analysis Analysis NNP cord-015369-72cjogxz 3822 4 and and CC cord-015369-72cjogxz 3822 5 Reporting Reporting NNP cord-015369-72cjogxz 3822 6 Outcome Outcome NNP cord-015369-72cjogxz 3822 7 System System NNP cord-015369-72cjogxz 3822 8 ( ( -LRB- cord-015369-72cjogxz 3822 9 BAROS BAROS NNP cord-015369-72cjogxz 3822 10 ) ) -RRB- cord-015369-72cjogxz 3822 11 was be VBD cord-015369-72cjogxz 3822 12 used use VBN cord-015369-72cjogxz 3822 13 for for IN cord-015369-72cjogxz 3822 14 the the DT cord-015369-72cjogxz 3822 15 quality quality NN cord-015369-72cjogxz 3822 16 of of IN cord-015369-72cjogxz 3822 17 life life NN cord-015369-72cjogxz 3822 18 investigation investigation NN cord-015369-72cjogxz 3822 19 which which WDT cord-015369-72cjogxz 3822 20 has have VBZ cord-015369-72cjogxz 3822 21 been be VBN cord-015369-72cjogxz 3822 22 international international JJ cord-015369-72cjogxz 3822 23 established establish VBN cord-015369-72cjogxz 3822 24 for for IN cord-015369-72cjogxz 3822 25 obesity obesity NN cord-015369-72cjogxz 3822 26 surgery surgery NN cord-015369-72cjogxz 3822 27 outcomes outcome NNS cord-015369-72cjogxz 3822 28 . . . cord-015369-72cjogxz 3823 1 Results result NNS cord-015369-72cjogxz 3823 2 . . . cord-015369-72cjogxz 3824 1 With with IN cord-015369-72cjogxz 3824 2 a a DT cord-015369-72cjogxz 3824 3 minimum minimum NN cord-015369-72cjogxz 3824 4 of of IN cord-015369-72cjogxz 3824 5 3 3 CD cord-015369-72cjogxz 3824 6 years year NNS cord-015369-72cjogxz 3824 7 follow follow VB cord-015369-72cjogxz 3824 8 - - HYPH cord-015369-72cjogxz 3824 9 up up NN cord-015369-72cjogxz 3824 10 our -PRON- PRP$ cord-015369-72cjogxz 3824 11 patients patient NNS cord-015369-72cjogxz 3824 12 showed show VBD cord-015369-72cjogxz 3824 13 a a DT cord-015369-72cjogxz 3824 14 mean mean JJ cord-015369-72cjogxz 3824 15 BMI BMI NNP cord-015369-72cjogxz 3824 16 of of IN cord-015369-72cjogxz 3824 17 28.8 28.8 CD cord-015369-72cjogxz 3824 18 kg kg NNP cord-015369-72cjogxz 3824 19 / / SYM cord-015369-72cjogxz 3824 20 m m NN cord-015369-72cjogxz 3824 21 2 2 CD cord-015369-72cjogxz 3825 1 ( ( -LRB- cord-015369-72cjogxz 3825 2 SD SD NNP cord-015369-72cjogxz 3825 3 ¼ ¼ NNP cord-015369-72cjogxz 3825 4 6.65 6.65 CD cord-015369-72cjogxz 3825 5 ) ) -RRB- cord-015369-72cjogxz 3825 6 . . . cord-015369-72cjogxz 3826 1 The the DT cord-015369-72cjogxz 3826 2 statistical statistical JJ cord-015369-72cjogxz 3826 3 analysis analysis NN cord-015369-72cjogxz 3826 4 ( ( -LRB- cord-015369-72cjogxz 3826 5 linear linear JJ cord-015369-72cjogxz 3826 6 regression regression NN cord-015369-72cjogxz 3826 7 ) ) -RRB- cord-015369-72cjogxz 3826 8 showed show VBD cord-015369-72cjogxz 3826 9 a a DT cord-015369-72cjogxz 3826 10 positive positive JJ cord-015369-72cjogxz 3826 11 correlation correlation NN cord-015369-72cjogxz 3826 12 between between IN cord-015369-72cjogxz 3826 13 quality quality NN cord-015369-72cjogxz 3826 14 of of IN cord-015369-72cjogxz 3826 15 life life NN cord-015369-72cjogxz 3826 16 and and CC cord-015369-72cjogxz 3826 17 weight weight NN cord-015369-72cjogxz 3826 18 loss loss NN cord-015369-72cjogxz 3826 19 , , , cord-015369-72cjogxz 3826 20 depending depend VBG cord-015369-72cjogxz 3826 21 on on IN cord-015369-72cjogxz 3826 22 operation operation NN cord-015369-72cjogxz 3826 23 method method NN cord-015369-72cjogxz 3826 24 . . . cord-015369-72cjogxz 3827 1 Additionally additionally RB cord-015369-72cjogxz 3827 2 we -PRON- PRP cord-015369-72cjogxz 3827 3 used use VBD cord-015369-72cjogxz 3827 4 a a DT cord-015369-72cjogxz 3827 5 partial partial JJ cord-015369-72cjogxz 3827 6 correlation correlation NN cord-015369-72cjogxz 3827 7 to to TO cord-015369-72cjogxz 3827 8 rule rule VB cord-015369-72cjogxz 3827 9 out out RP cord-015369-72cjogxz 3827 10 the the DT cord-015369-72cjogxz 3827 11 influence influence NN cord-015369-72cjogxz 3827 12 of of IN cord-015369-72cjogxz 3827 13 weight weight NN cord-015369-72cjogxz 3827 14 loss loss NN cord-015369-72cjogxz 3827 15 and and CC cord-015369-72cjogxz 3827 16 remarked remark VBD cord-015369-72cjogxz 3827 17 a a DT cord-015369-72cjogxz 3827 18 significant significant JJ cord-015369-72cjogxz 3827 19 result result NN cord-015369-72cjogxz 3827 20 ( ( -LRB- cord-015369-72cjogxz 3827 21 r r NNP cord-015369-72cjogxz 3827 22 ¼ ¼ NNP cord-015369-72cjogxz 3827 23 0.234 0.234 CD cord-015369-72cjogxz 3827 24 , , , cord-015369-72cjogxz 3827 25 p p NN cord-015369-72cjogxz 3827 26 ¼ ¼ CD cord-015369-72cjogxz 3827 27 0.000 0.000 CD cord-015369-72cjogxz 3827 28 ) ) -RRB- cord-015369-72cjogxz 3827 29 . . . cord-015369-72cjogxz 3828 1 With with IN cord-015369-72cjogxz 3828 2 a a DT cord-015369-72cjogxz 3828 3 t t NN cord-015369-72cjogxz 3828 4 - - HYPH cord-015369-72cjogxz 3828 5 test test NN cord-015369-72cjogxz 3828 6 it -PRON- PRP cord-015369-72cjogxz 3828 7 could could MD cord-015369-72cjogxz 3828 8 be be VB cord-015369-72cjogxz 3828 9 demonstrated demonstrate VBN cord-015369-72cjogxz 3828 10 , , , cord-015369-72cjogxz 3828 11 that that IN cord-015369-72cjogxz 3828 12 patients patient NNS cord-015369-72cjogxz 3828 13 with with IN cord-015369-72cjogxz 3828 14 a a DT cord-015369-72cjogxz 3828 15 Laparoscopic Laparoscopic NNP cord-015369-72cjogxz 3828 16 Gastric Gastric NNP cord-015369-72cjogxz 3828 17 Bypass Bypass NNP cord-015369-72cjogxz 3828 18 observed observe VBD cord-015369-72cjogxz 3828 19 a a DT cord-015369-72cjogxz 3828 20 significant significant JJ cord-015369-72cjogxz 3828 21 different different JJ cord-015369-72cjogxz 3828 22 quality quality NN cord-015369-72cjogxz 3828 23 of of IN cord-015369-72cjogxz 3828 24 life life NN cord-015369-72cjogxz 3828 25 , , , cord-015369-72cjogxz 3828 26 than than IN cord-015369-72cjogxz 3828 27 patients patient NNS cord-015369-72cjogxz 3828 28 with with IN cord-015369-72cjogxz 3828 29 an an DT cord-015369-72cjogxz 3828 30 AGB AGB NNP cord-015369-72cjogxz 3828 31 independent independent JJ cord-015369-72cjogxz 3828 32 from from IN cord-015369-72cjogxz 3828 33 weight weight NN cord-015369-72cjogxz 3828 34 loss loss NN cord-015369-72cjogxz 3828 35 ( ( -LRB- cord-015369-72cjogxz 3828 36 t t NN cord-015369-72cjogxz 3828 37 ( ( -LRB- cord-015369-72cjogxz 3828 38 123 123 CD cord-015369-72cjogxz 3828 39 ) ) -RRB- cord-015369-72cjogxz 3828 40 ¼ ¼ NNP cord-015369-72cjogxz 3828 41 3.477 3.477 CD cord-015369-72cjogxz 3828 42 , , , cord-015369-72cjogxz 3828 43 p p NN cord-015369-72cjogxz 3828 44 ¼ ¼ CD cord-015369-72cjogxz 3828 45 0.001 0.001 CD cord-015369-72cjogxz 3828 46 ) ) -RRB- cord-015369-72cjogxz 3828 47 . . . cord-015369-72cjogxz 3829 1 Conclusions conclusion NNS cord-015369-72cjogxz 3829 2 . . . cord-015369-72cjogxz 3830 1 Independently independently RB cord-015369-72cjogxz 3830 2 of of IN cord-015369-72cjogxz 3830 3 the the DT cord-015369-72cjogxz 3830 4 amount amount NN cord-015369-72cjogxz 3830 5 of of IN cord-015369-72cjogxz 3830 6 weight weight NN cord-015369-72cjogxz 3830 7 loss loss NN cord-015369-72cjogxz 3830 8 , , , cord-015369-72cjogxz 3830 9 quality quality NN cord-015369-72cjogxz 3830 10 of of IN cord-015369-72cjogxz 3830 11 life life NN cord-015369-72cjogxz 3830 12 is be VBZ cord-015369-72cjogxz 3830 13 different different JJ cord-015369-72cjogxz 3830 14 between between IN cord-015369-72cjogxz 3830 15 surgical surgical JJ cord-015369-72cjogxz 3830 16 procedures procedure NNS cord-015369-72cjogxz 3830 17 . . . cord-015369-72cjogxz 3831 1 Wir Wir NNP cord-015369-72cjogxz 3831 2 haben haben NNP cord-015369-72cjogxz 3831 3 versucht versucht NNP cord-015369-72cjogxz 3831 4 , , , cord-015369-72cjogxz 3831 5 mit mit NNP cord-015369-72cjogxz 3831 6 einem einem NNP cord-015369-72cjogxz 3831 7 standardisierten standardisierten NNP cord-015369-72cjogxz 3831 8 modifizierten modifizierten NNP cord-015369-72cjogxz 3831 9 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3831 10 + + CC cord-015369-72cjogxz 3832 1 -System -system NN cord-015369-72cjogxz 3832 2 und und RB cord-015369-72cjogxz 3833 1 einer einer NNP cord-015369-72cjogxz 3833 2 physikalisch physikalisch NNP cord-015369-72cjogxz 3833 3 - - HYPH cord-015369-72cjogxz 3833 4 technischen technischen NNP cord-015369-72cjogxz 3833 5 Analyse Analyse NNP cord-015369-72cjogxz 3833 6 die die VB cord-015369-72cjogxz 3834 1 Anwendungstechnik Anwendungstechnik NNP cord-015369-72cjogxz 3834 2 zu zu XX cord-015369-72cjogxz 3834 3 optimieren optimieren NN cord-015369-72cjogxz 3835 1 und und NNP cord-015369-72cjogxz 3835 2 die die VB cord-015369-72cjogxz 3836 1 Suffizienzrate Suffizienzrate NNP cord-015369-72cjogxz 3836 2 zu zu NNP cord-015369-72cjogxz 3836 3 erhöhen erhöhen NNP cord-015369-72cjogxz 3836 4 . . . cord-015369-72cjogxz 3837 1 Methodik Methodik NNP cord-015369-72cjogxz 3837 2 . . . cord-015369-72cjogxz 3838 1 I -PRON- PRP cord-015369-72cjogxz 3838 2 m be VBP cord-015369-72cjogxz 3838 3 Rahmen Rahmen NNP cord-015369-72cjogxz 3838 4 einer einer NNP cord-015369-72cjogxz 3838 5 Versuchsanordnung Versuchsanordnung NNP cord-015369-72cjogxz 3838 6 wurden wurden NNS cord-015369-72cjogxz 3838 7 die die VBP cord-015369-72cjogxz 3838 8 physikalischen physikalischen NNP cord-015369-72cjogxz 3838 9 Grundlagen Grundlagen NNP cord-015369-72cjogxz 3838 10 untersucht untersucht NN cord-015369-72cjogxz 3838 11 Background Background NNP cord-015369-72cjogxz 3838 12 . . . cord-015369-72cjogxz 3839 1 The the DT cord-015369-72cjogxz 3839 2 application application NN cord-015369-72cjogxz 3839 3 of of IN cord-015369-72cjogxz 3839 4 the the DT cord-015369-72cjogxz 3839 5 abdominal abdominal JJ cord-015369-72cjogxz 3839 6 vacuum vacuum NN cord-015369-72cjogxz 3839 7 assisted assist VBN cord-015369-72cjogxz 3839 8 closure closure NN cord-015369-72cjogxz 3839 9 ( ( -LRB- cord-015369-72cjogxz 3839 10 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3839 11 ) ) -RRB- cord-015369-72cjogxz 3839 12 system system NN cord-015369-72cjogxz 3839 13 has have VBZ cord-015369-72cjogxz 3839 14 become become VBN cord-015369-72cjogxz 3839 15 a a DT cord-015369-72cjogxz 3839 16 promising promising JJ cord-015369-72cjogxz 3839 17 treatment treatment NN cord-015369-72cjogxz 3839 18 strategy strategy NN cord-015369-72cjogxz 3839 19 in in IN cord-015369-72cjogxz 3839 20 critical critical JJ cord-015369-72cjogxz 3839 21 ill ill JJ cord-015369-72cjogxz 3839 22 patients patient NNS cord-015369-72cjogxz 3839 23 with with IN cord-015369-72cjogxz 3839 24 abdominal abdominal JJ cord-015369-72cjogxz 3839 25 sepsis sepsis NN cord-015369-72cjogxz 3839 26 requiring require VBG cord-015369-72cjogxz 3839 27 surgical surgical JJ cord-015369-72cjogxz 3839 28 therapy therapy NN cord-015369-72cjogxz 3839 29 and and CC cord-015369-72cjogxz 3839 30 open open JJ cord-015369-72cjogxz 3839 31 abdomen abdoman NNS cord-015369-72cjogxz 3839 32 . . . cord-015369-72cjogxz 3840 1 However however RB cord-015369-72cjogxz 3840 2 , , , cord-015369-72cjogxz 3840 3 fascial fascial JJ cord-015369-72cjogxz 3840 4 retraction retraction NN cord-015369-72cjogxz 3840 5 and and CC cord-015369-72cjogxz 3840 6 high high JJ cord-015369-72cjogxz 3840 7 rates rate NNS cord-015369-72cjogxz 3840 8 of of IN cord-015369-72cjogxz 3840 9 incomplete incomplete JJ cord-015369-72cjogxz 3840 10 fascial fascial JJ cord-015369-72cjogxz 3840 11 closure closure NN cord-015369-72cjogxz 3840 12 up up IN cord-015369-72cjogxz 3840 13 to to TO cord-015369-72cjogxz 3840 14 70 70 CD cord-015369-72cjogxz 3840 15 % % NN cord-015369-72cjogxz 3840 16 with with IN cord-015369-72cjogxz 3840 17 subsequent subsequent JJ cord-015369-72cjogxz 3840 18 high high JJ cord-015369-72cjogxz 3840 19 incidence incidence NN cord-015369-72cjogxz 3840 20 of of IN cord-015369-72cjogxz 3840 21 incisional incisional JJ cord-015369-72cjogxz 3840 22 hernia hernia NNP cord-015369-72cjogxz 3840 23 have have VBP cord-015369-72cjogxz 3840 24 been be VBN cord-015369-72cjogxz 3840 25 reported report VBN cord-015369-72cjogxz 3840 26 in in IN cord-015369-72cjogxz 3840 27 literature literature NN cord-015369-72cjogxz 3840 28 . . . cord-015369-72cjogxz 3841 1 The the DT cord-015369-72cjogxz 3841 2 aim aim NN cord-015369-72cjogxz 3841 3 of of IN cord-015369-72cjogxz 3841 4 this this DT cord-015369-72cjogxz 3841 5 study study NN cord-015369-72cjogxz 3841 6 was be VBD cord-015369-72cjogxz 3841 7 to to TO cord-015369-72cjogxz 3841 8 analyse analyse VB cord-015369-72cjogxz 3841 9 the the DT cord-015369-72cjogxz 3841 10 application application NN cord-015369-72cjogxz 3841 11 of of IN cord-015369-72cjogxz 3841 12 the the DT cord-015369-72cjogxz 3841 13 abdominal abdominal JJ cord-015369-72cjogxz 3841 14 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3841 15 therapy therapy NN cord-015369-72cjogxz 3841 16 in in IN cord-015369-72cjogxz 3841 17 patients patient NNS cord-015369-72cjogxz 3841 18 with with IN cord-015369-72cjogxz 3841 19 abdominal abdominal JJ cord-015369-72cjogxz 3841 20 sepsis sepsis NN cord-015369-72cjogxz 3841 21 regarding regard VBG cord-015369-72cjogxz 3841 22 rate rate NN cord-015369-72cjogxz 3841 23 of of IN cord-015369-72cjogxz 3841 24 fascial fascial JJ cord-015369-72cjogxz 3841 25 closure closure NN cord-015369-72cjogxz 3841 26 and and CC cord-015369-72cjogxz 3841 27 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3841 28 associated associate VBD cord-015369-72cjogxz 3841 29 morbidity morbidity NN cord-015369-72cjogxz 3841 30 . . . cord-015369-72cjogxz 3842 1 Methods method NNS cord-015369-72cjogxz 3842 2 . . . cord-015369-72cjogxz 3843 1 The the DT cord-015369-72cjogxz 3843 2 study study NN cord-015369-72cjogxz 3843 3 retrospectively retrospectively RB cord-015369-72cjogxz 3843 4 includes include VBZ cord-015369-72cjogxz 3843 5 all all DT cord-015369-72cjogxz 3843 6 patients patient NNS cord-015369-72cjogxz 3843 7 with with IN cord-015369-72cjogxz 3843 8 abdominal abdominal JJ cord-015369-72cjogxz 3843 9 sepsis sepsis NN cord-015369-72cjogxz 3843 10 requring requre VBG cord-015369-72cjogxz 3843 11 emergency emergency NN cord-015369-72cjogxz 3843 12 laparotomy laparotomy NN cord-015369-72cjogxz 3843 13 with with IN cord-015369-72cjogxz 3843 14 application application NN cord-015369-72cjogxz 3843 15 of of IN cord-015369-72cjogxz 3843 16 abdominal abdominal JJ cord-015369-72cjogxz 3843 17 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3843 18 therapy therapy NN cord-015369-72cjogxz 3843 19 between between IN cord-015369-72cjogxz 3843 20 november november NNP cord-015369-72cjogxz 3843 21 2006 2006 CD cord-015369-72cjogxz 3843 22 and and CC cord-015369-72cjogxz 3843 23 november november NNP cord-015369-72cjogxz 3843 24 2008 2008 CD cord-015369-72cjogxz 3843 25 at at IN cord-015369-72cjogxz 3843 26 our -PRON- PRP$ cord-015369-72cjogxz 3843 27 department department NN cord-015369-72cjogxz 3843 28 ( ( -LRB- cord-015369-72cjogxz 3843 29 80 80 CD cord-015369-72cjogxz 3843 30 patients patient NNS cord-015369-72cjogxz 3843 31 , , , cord-015369-72cjogxz 3843 32 51 51 CD cord-015369-72cjogxz 3843 33 male/29 male/29 NNP cord-015369-72cjogxz 3843 34 female female NN cord-015369-72cjogxz 3843 35 ; ; : cord-015369-72cjogxz 3843 36 median median NN cord-015369-72cjogxz 3843 37 age age NN cord-015369-72cjogxz 3843 38 65 65 CD cord-015369-72cjogxz 3843 39 , , , cord-015369-72cjogxz 3843 40 range range VBP cord-015369-72cjogxz 3843 41 35 35 CD cord-015369-72cjogxz 3843 42 to to IN cord-015369-72cjogxz 3843 43 87 87 CD cord-015369-72cjogxz 3843 44 ) ) -RRB- cord-015369-72cjogxz 3843 45 . . . cord-015369-72cjogxz 3844 1 Results result NNS cord-015369-72cjogxz 3844 2 . . . cord-015369-72cjogxz 3845 1 The the DT cord-015369-72cjogxz 3845 2 lenght lenght NN cord-015369-72cjogxz 3845 3 of of IN cord-015369-72cjogxz 3845 4 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3845 5 therapy therapy NN cord-015369-72cjogxz 3845 6 ranged range VBD cord-015369-72cjogxz 3845 7 from from IN cord-015369-72cjogxz 3845 8 1 1 CD cord-015369-72cjogxz 3845 9 to to IN cord-015369-72cjogxz 3845 10 13 13 CD cord-015369-72cjogxz 3845 11 days day NNS cord-015369-72cjogxz 3845 12 ( ( -LRB- cord-015369-72cjogxz 3845 13 median median JJ cord-015369-72cjogxz 3845 14 4 4 CD cord-015369-72cjogxz 3845 15 days day NNS cord-015369-72cjogxz 3845 16 ) ) -RRB- cord-015369-72cjogxz 3845 17 with with IN cord-015369-72cjogxz 3845 18 0 0 CD cord-015369-72cjogxz 3845 19 to to IN cord-015369-72cjogxz 3845 20 5 5 CD cord-015369-72cjogxz 3845 21 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3845 22 changes change NNS cord-015369-72cjogxz 3845 23 ( ( -LRB- cord-015369-72cjogxz 3845 24 median median JJ cord-015369-72cjogxz 3845 25 1 1 CD cord-015369-72cjogxz 3845 26 ) ) -RRB- cord-015369-72cjogxz 3845 27 . . . cord-015369-72cjogxz 3846 1 Complete complete JJ cord-015369-72cjogxz 3846 2 fascial fascial JJ cord-015369-72cjogxz 3846 3 closure closure NN cord-015369-72cjogxz 3846 4 of of IN cord-015369-72cjogxz 3846 5 the the DT cord-015369-72cjogxz 3846 6 abdomen abdomen NN cord-015369-72cjogxz 3846 7 was be VBD cord-015369-72cjogxz 3846 8 feasible feasible JJ cord-015369-72cjogxz 3846 9 in in IN cord-015369-72cjogxz 3846 10 60 60 CD cord-015369-72cjogxz 3846 11 patients patient NNS cord-015369-72cjogxz 3846 12 ( ( -LRB- cord-015369-72cjogxz 3846 13 75 75 CD cord-015369-72cjogxz 3846 14 % % NN cord-015369-72cjogxz 3846 15 ) ) -RRB- cord-015369-72cjogxz 3846 16 , , , cord-015369-72cjogxz 3846 17 partial partial JJ cord-015369-72cjogxz 3846 18 closure closure NN cord-015369-72cjogxz 3846 19 with with IN cord-015369-72cjogxz 3846 20 mesh mesh NN cord-015369-72cjogxz 3846 21 graft graft NN cord-015369-72cjogxz 3846 22 implantation implantation NN cord-015369-72cjogxz 3846 23 ( ( -LRB- cord-015369-72cjogxz 3846 24 Vicryl Vicryl NNP cord-015369-72cjogxz 3846 25 , , , cord-015369-72cjogxz 3846 26 Goretex Goretex NNP cord-015369-72cjogxz 3846 27 ) ) -RRB- cord-015369-72cjogxz 3846 28 in in IN cord-015369-72cjogxz 3846 29 7 7 CD cord-015369-72cjogxz 3846 30 patients patient NNS cord-015369-72cjogxz 3846 31 ( ( -LRB- cord-015369-72cjogxz 3846 32 8,75 8,75 CD cord-015369-72cjogxz 3846 33 % % NN cord-015369-72cjogxz 3846 34 ) ) -RRB- cord-015369-72cjogxz 3846 35 , , . cord-015369-72cjogxz 3847 1 no no DT cord-015369-72cjogxz 3847 2 closure closure NN cord-015369-72cjogxz 3847 3 in in IN cord-015369-72cjogxz 3847 4 3 3 CD cord-015369-72cjogxz 3847 5 patients patient NNS cord-015369-72cjogxz 3847 6 ( ( -LRB- cord-015369-72cjogxz 3847 7 3.75 3.75 CD cord-015369-72cjogxz 3847 8 % % NN cord-015369-72cjogxz 3847 9 ) ) -RRB- cord-015369-72cjogxz 3847 10 , , , cord-015369-72cjogxz 3847 11 and and CC cord-015369-72cjogxz 3847 12 10 10 CD cord-015369-72cjogxz 3847 13 patients patient NNS cord-015369-72cjogxz 3847 14 died die VBD cord-015369-72cjogxz 3847 15 with with IN cord-015369-72cjogxz 3847 16 the the DT cord-015369-72cjogxz 3847 17 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3847 18 system system NN cord-015369-72cjogxz 3847 19 in in IN cord-015369-72cjogxz 3847 20 situ situ NN cord-015369-72cjogxz 3847 21 ( ( -LRB- cord-015369-72cjogxz 3847 22 12.5 12.5 CD cord-015369-72cjogxz 3847 23 % % NN cord-015369-72cjogxz 3847 24 ) ) -RRB- cord-015369-72cjogxz 3847 25 . . . cord-015369-72cjogxz 3848 1 13 13 CD cord-015369-72cjogxz 3848 2 incisional incisional JJ cord-015369-72cjogxz 3848 3 site site NN cord-015369-72cjogxz 3848 4 infections infection NNS cord-015369-72cjogxz 3848 5 and and CC cord-015369-72cjogxz 3848 6 8 8 CD cord-015369-72cjogxz 3848 7 intraabdominal intraabdominal JJ cord-015369-72cjogxz 3848 8 abscesses abscess NNS cord-015369-72cjogxz 3848 9 were be VBD cord-015369-72cjogxz 3848 10 observed observe VBN cord-015369-72cjogxz 3848 11 postoperatively postoperatively RB cord-015369-72cjogxz 3848 12 , , , cord-015369-72cjogxz 3848 13 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3848 14 associated associate VBD cord-015369-72cjogxz 3848 15 morbidity morbidity NN cord-015369-72cjogxz 3848 16 was be VBD cord-015369-72cjogxz 3848 17 7.5 7.5 CD cord-015369-72cjogxz 3848 18 % % NN cord-015369-72cjogxz 3848 19 with with IN cord-015369-72cjogxz 3848 20 4 4 CD cord-015369-72cjogxz 3848 21 enterocutaneous enterocutaneous JJ cord-015369-72cjogxz 3848 22 fistulas fistula NNS cord-015369-72cjogxz 3848 23 and and CC cord-015369-72cjogxz 3848 24 2 2 CD cord-015369-72cjogxz 3848 25 bleeding bleed VBG cord-015369-72cjogxz 3848 26 complications complication NNS cord-015369-72cjogxz 3848 27 . . . cord-015369-72cjogxz 3849 1 Conclusions conclusion NNS cord-015369-72cjogxz 3849 2 . . . cord-015369-72cjogxz 3850 1 The the DT cord-015369-72cjogxz 3850 2 study study NN cord-015369-72cjogxz 3850 3 confirms confirm VBZ cord-015369-72cjogxz 3850 4 the the DT cord-015369-72cjogxz 3850 5 feasibility feasibility NN cord-015369-72cjogxz 3850 6 of of IN cord-015369-72cjogxz 3850 7 abdominal abdominal JJ cord-015369-72cjogxz 3850 8 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3850 9 therapy therapy NN cord-015369-72cjogxz 3850 10 in in IN cord-015369-72cjogxz 3850 11 patients patient NNS cord-015369-72cjogxz 3850 12 with with IN cord-015369-72cjogxz 3850 13 severe severe JJ cord-015369-72cjogxz 3850 14 abdominal abdominal JJ cord-015369-72cjogxz 3850 15 sepsis sepsis NN cord-015369-72cjogxz 3850 16 guaranteeing guarantee VBG cord-015369-72cjogxz 3850 17 a a DT cord-015369-72cjogxz 3850 18 high high JJ cord-015369-72cjogxz 3850 19 rate rate NN cord-015369-72cjogxz 3850 20 of of IN cord-015369-72cjogxz 3850 21 fascial fascial JJ cord-015369-72cjogxz 3850 22 closure closure NN cord-015369-72cjogxz 3850 23 and and CC cord-015369-72cjogxz 3850 24 low low JJ cord-015369-72cjogxz 3850 25 morbidity morbidity NN cord-015369-72cjogxz 3850 26 . . . cord-015369-72cjogxz 3851 1 Methods method NNS cord-015369-72cjogxz 3851 2 . . . cord-015369-72cjogxz 3852 1 Retrospectively retrospectively RB cord-015369-72cjogxz 3852 2 reviewed review VBN cord-015369-72cjogxz 3852 3 patient patient JJ cord-015369-72cjogxz 3852 4 records record NNS cord-015369-72cjogxz 3852 5 between between IN cord-015369-72cjogxz 3852 6 August August NNP cord-015369-72cjogxz 3852 7 2003 2003 CD cord-015369-72cjogxz 3852 8 and and CC cord-015369-72cjogxz 3852 9 December December NNP cord-015369-72cjogxz 3852 10 2008 2008 CD cord-015369-72cjogxz 3852 11 12 12 CD cord-015369-72cjogxz 3852 12 patients patient NNS cord-015369-72cjogxz 3852 13 with with IN cord-015369-72cjogxz 3852 14 moderate moderate JJ cord-015369-72cjogxz 3852 15 or or CC cord-015369-72cjogxz 3852 16 high high JJ cord-015369-72cjogxz 3852 17 volume volume NN cord-015369-72cjogxz 3852 18 output output NN cord-015369-72cjogxz 3852 19 GI GI NNP cord-015369-72cjogxz 3852 20 fistulae fistulae NNP cord-015369-72cjogxz 3852 21 , , , cord-015369-72cjogxz 3852 22 where where WRB cord-015369-72cjogxz 3852 23 conventional conventional JJ cord-015369-72cjogxz 3852 24 treatment treatment NN cord-015369-72cjogxz 3852 25 had have VBD cord-015369-72cjogxz 3852 26 failed fail VBN cord-015369-72cjogxz 3852 27 to to TO cord-015369-72cjogxz 3852 28 prevent prevent VB cord-015369-72cjogxz 3852 29 skin skin NN cord-015369-72cjogxz 3852 30 excoriaton excoriaton NN cord-015369-72cjogxz 3852 31 , , , cord-015369-72cjogxz 3852 32 had have VBD cord-015369-72cjogxz 3852 33 been be VBN cord-015369-72cjogxz 3852 34 included include VBN cord-015369-72cjogxz 3852 35 . . . cord-015369-72cjogxz 3853 1 They -PRON- PRP cord-015369-72cjogxz 3853 2 underwent undergo VBD cord-015369-72cjogxz 3853 3 the the DT cord-015369-72cjogxz 3853 4 fistula fistula NN cord-015369-72cjogxz 3853 5 - - HYPH cord-015369-72cjogxz 3853 6 V.A.C. v.a.c. NN cord-015369-72cjogxz 3853 7 + + CC cord-015369-72cjogxz 3853 8 procedure procedure NN cord-015369-72cjogxz 3853 9 using use VBG cord-015369-72cjogxz 3853 10 the the DT cord-015369-72cjogxz 3853 11 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3853 12 system system NN cord-015369-72cjogxz 3853 13 sized size VBN cord-015369-72cjogxz 3853 14 from from IN cord-015369-72cjogxz 3853 15 standard standard JJ cord-015369-72cjogxz 3853 16 sponge sponge NN cord-015369-72cjogxz 3853 17 supplies supply NNS cord-015369-72cjogxz 3853 18 , , , cord-015369-72cjogxz 3853 19 topical topical JJ cord-015369-72cjogxz 3853 20 negative negative JJ cord-015369-72cjogxz 3853 21 pressure pressure NN cord-015369-72cjogxz 3853 22 ( ( -LRB- cord-015369-72cjogxz 3853 23 at at IN cord-015369-72cjogxz 3853 24 most most JJS cord-015369-72cjogxz 3853 25 75 75 CD cord-015369-72cjogxz 3853 26 mmHg mmHg NNS cord-015369-72cjogxz 3853 27 ) ) -RRB- cord-015369-72cjogxz 3853 28 and and CC cord-015369-72cjogxz 3853 29 ostomy ostomy NN cord-015369-72cjogxz 3853 30 appliances appliance NNS cord-015369-72cjogxz 3853 31 . . . cord-015369-72cjogxz 3854 1 The the DT cord-015369-72cjogxz 3854 2 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3854 3 + + CC cord-015369-72cjogxz 3854 4 dressing dressing NN cord-015369-72cjogxz 3854 5 was be VBD cord-015369-72cjogxz 3854 6 changed change VBN cord-015369-72cjogxz 3854 7 every every DT cord-015369-72cjogxz 3854 8 two two CD cord-015369-72cjogxz 3854 9 days day NNS cord-015369-72cjogxz 3854 10 . . . cord-015369-72cjogxz 3855 1 Results result NNS cord-015369-72cjogxz 3855 2 . . . cord-015369-72cjogxz 3856 1 The the DT cord-015369-72cjogxz 3856 2 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3856 3 system system NN cord-015369-72cjogxz 3856 4 was be VBD cord-015369-72cjogxz 3856 5 found find VBN cord-015369-72cjogxz 3856 6 to to TO cord-015369-72cjogxz 3856 7 be be VB cord-015369-72cjogxz 3856 8 highly highly RB cord-015369-72cjogxz 3856 9 effective effective JJ cord-015369-72cjogxz 3856 10 in in IN cord-015369-72cjogxz 3856 11 controlling control VBG cord-015369-72cjogxz 3856 12 the the DT cord-015369-72cjogxz 3856 13 fistula fistula NN cord-015369-72cjogxz 3856 14 effluent effluent NN cord-015369-72cjogxz 3856 15 and and CC cord-015369-72cjogxz 3856 16 in in IN cord-015369-72cjogxz 3856 17 promoting promote VBG cord-015369-72cjogxz 3856 18 healing healing NN cord-015369-72cjogxz 3856 19 of of IN cord-015369-72cjogxz 3856 20 excoriated excoriate VBN cord-015369-72cjogxz 3856 21 skin skin NN cord-015369-72cjogxz 3856 22 . . . cord-015369-72cjogxz 3857 1 Complete complete JJ cord-015369-72cjogxz 3857 2 healing healing NN cord-015369-72cjogxz 3857 3 of of IN cord-015369-72cjogxz 3857 4 fistula fistula NN cord-015369-72cjogxz 3857 5 was be VBD cord-015369-72cjogxz 3857 6 achieved achieve VBN cord-015369-72cjogxz 3857 7 in in IN cord-015369-72cjogxz 3857 8 five five CD cord-015369-72cjogxz 3857 9 patients patient NNS cord-015369-72cjogxz 3857 10 , , , cord-015369-72cjogxz 3857 11 intestinal intestinal JJ cord-015369-72cjogxz 3857 12 reanastomosis reanastomosis NN cord-015369-72cjogxz 3857 13 in in IN cord-015369-72cjogxz 3857 14 five five CD cord-015369-72cjogxz 3857 15 patients patient NNS cord-015369-72cjogxz 3857 16 , , , cord-015369-72cjogxz 3857 17 palliative palliative JJ cord-015369-72cjogxz 3857 18 care care NN cord-015369-72cjogxz 3857 19 using use VBG cord-015369-72cjogxz 3857 20 fistula fistula NN cord-015369-72cjogxz 3857 21 ostomy ostomy NN cord-015369-72cjogxz 3857 22 appliance appliance NN cord-015369-72cjogxz 3857 23 in in IN cord-015369-72cjogxz 3857 24 two two CD cord-015369-72cjogxz 3857 25 of of IN cord-015369-72cjogxz 3857 26 twelve twelve CD cord-015369-72cjogxz 3857 27 patients patient NNS cord-015369-72cjogxz 3857 28 . . . cord-015369-72cjogxz 3858 1 Conclusions conclusion NNS cord-015369-72cjogxz 3858 2 . . . cord-015369-72cjogxz 3859 1 The the DT cord-015369-72cjogxz 3859 2 modified modify VBN cord-015369-72cjogxz 3859 3 fistula fistula NN cord-015369-72cjogxz 3859 4 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3859 5 + + CC cord-015369-72cjogxz 3859 6 system system NN cord-015369-72cjogxz 3859 7 can can MD cord-015369-72cjogxz 3859 8 be be VB cord-015369-72cjogxz 3859 9 an an DT cord-015369-72cjogxz 3859 10 effective effective JJ cord-015369-72cjogxz 3859 11 and and CC cord-015369-72cjogxz 3859 12 economically economically RB cord-015369-72cjogxz 3859 13 viable viable JJ cord-015369-72cjogxz 3859 14 method method NN cord-015369-72cjogxz 3859 15 of of IN cord-015369-72cjogxz 3859 16 containing contain VBG cord-015369-72cjogxz 3859 17 fistula fistula NN cord-015369-72cjogxz 3859 18 effluent effluent NN cord-015369-72cjogxz 3859 19 and and CC cord-015369-72cjogxz 3859 20 protecting protect VBG cord-015369-72cjogxz 3859 21 the the DT cord-015369-72cjogxz 3859 22 skin skin NN cord-015369-72cjogxz 3859 23 of of IN cord-015369-72cjogxz 3859 24 patients patient NNS cord-015369-72cjogxz 3859 25 with with IN cord-015369-72cjogxz 3859 26 enterocutaneous enterocutaneous NNP cord-015369-72cjogxz 3859 27 fistulae fistulae NNP cord-015369-72cjogxz 3859 28 . . . cord-015369-72cjogxz 3860 1 The the DT cord-015369-72cjogxz 3860 2 V.A.C. V.A.C. NNP cord-015369-72cjogxz 3860 3 + + CC cord-015369-72cjogxz 3860 4 System System NNP cord-015369-72cjogxz 3860 5 may may MD cord-015369-72cjogxz 3860 6 also also RB cord-015369-72cjogxz 3860 7 actually actually RB cord-015369-72cjogxz 3860 8 promote promote VB cord-015369-72cjogxz 3860 9 spontaneous spontaneous JJ cord-015369-72cjogxz 3860 10 healing healing NN cord-015369-72cjogxz 3860 11 . . . cord-015369-72cjogxz 3861 1 Background background NN cord-015369-72cjogxz 3861 2 . . . cord-015369-72cjogxz 3862 1 Surgical surgical JJ cord-015369-72cjogxz 3862 2 site site NN cord-015369-72cjogxz 3862 3 infection infection NN cord-015369-72cjogxz 3862 4 ( ( -LRB- cord-015369-72cjogxz 3862 5 SSI SSI NNP cord-015369-72cjogxz 3862 6 ) ) -RRB- cord-015369-72cjogxz 3862 7 rates rate NNS cord-015369-72cjogxz 3862 8 for for IN cord-015369-72cjogxz 3862 9 colorectal colorectal JJ cord-015369-72cjogxz 3862 10 surgery surgery NN cord-015369-72cjogxz 3862 11 range range NN cord-015369-72cjogxz 3862 12 between between IN cord-015369-72cjogxz 3862 13 5 5 CD cord-015369-72cjogxz 3862 14 and and CC cord-015369-72cjogxz 3862 15 30 30 CD cord-015369-72cjogxz 3862 16 % % NN cord-015369-72cjogxz 3862 17 . . . cord-015369-72cjogxz 3863 1 We -PRON- PRP cord-015369-72cjogxz 3863 2 performed perform VBD cord-015369-72cjogxz 3863 3 a a DT cord-015369-72cjogxz 3863 4 surveillance surveillance NN cord-015369-72cjogxz 3863 5 to to TO cord-015369-72cjogxz 3863 6 determine determine VB cord-015369-72cjogxz 3863 7 our -PRON- PRP$ cord-015369-72cjogxz 3863 8 rate rate NN cord-015369-72cjogxz 3863 9 and and CC cord-015369-72cjogxz 3863 10 to to TO cord-015369-72cjogxz 3863 11 identify identify VB cord-015369-72cjogxz 3863 12 risk risk NN cord-015369-72cjogxz 3863 13 factors factor NNS cord-015369-72cjogxz 3863 14 . . . cord-015369-72cjogxz 3864 1 Methods method NNS cord-015369-72cjogxz 3864 2 . . . cord-015369-72cjogxz 3865 1 In in IN cord-015369-72cjogxz 3865 2 2008 2008 CD cord-015369-72cjogxz 3865 3 cases case NNS cord-015369-72cjogxz 3865 4 with with IN cord-015369-72cjogxz 3865 5 colon colon NN cord-015369-72cjogxz 3865 6 surgery surgery NN cord-015369-72cjogxz 3865 7 according accord VBG cord-015369-72cjogxz 3865 8 to to IN cord-015369-72cjogxz 3865 9 the the DT cord-015369-72cjogxz 3865 10 NNIS·COLO NNIS·COLO NNP cord-015369-72cjogxz 3865 11 definition definition NN cord-015369-72cjogxz 3865 12 or or CC cord-015369-72cjogxz 3865 13 a a DT cord-015369-72cjogxz 3865 14 rectal rectal JJ cord-015369-72cjogxz 3865 15 resection resection NN cord-015369-72cjogxz 3865 16 were be VBD cord-015369-72cjogxz 3865 17 collected collect VBN cord-015369-72cjogxz 3865 18 prospectively prospectively RB cord-015369-72cjogxz 3865 19 . . . cord-015369-72cjogxz 3866 1 SSI SSI NNP cord-015369-72cjogxz 3866 2 was be VBD cord-015369-72cjogxz 3866 3 diagnosed diagnose VBN cord-015369-72cjogxz 3866 4 following follow VBG cord-015369-72cjogxz 3866 5 CDC CDC NNP cord-015369-72cjogxz 3866 6 guidelines guideline NNS cord-015369-72cjogxz 3866 7 . . . cord-015369-72cjogxz 3867 1 Followup followup NN cord-015369-72cjogxz 3867 2 lasted last VBD cord-015369-72cjogxz 3867 3 for for IN cord-015369-72cjogxz 3867 4 30 30 CD cord-015369-72cjogxz 3867 5 days day NNS cord-015369-72cjogxz 3867 6 , , , cord-015369-72cjogxz 3867 7 discharged discharge VBN cord-015369-72cjogxz 3867 8 patients patient NNS cord-015369-72cjogxz 3867 9 were be VBD cord-015369-72cjogxz 3867 10 contacted contact VBN cord-015369-72cjogxz 3867 11 by by IN cord-015369-72cjogxz 3867 12 phone phone NN cord-015369-72cjogxz 3867 13 . . . cord-015369-72cjogxz 3868 1 Results result NNS cord-015369-72cjogxz 3868 2 . . . cord-015369-72cjogxz 3869 1 One one CD cord-015369-72cjogxz 3869 2 hundred hundred CD cord-015369-72cjogxz 3869 3 and and CC cord-015369-72cjogxz 3869 4 twenty twenty CD cord-015369-72cjogxz 3869 5 - - HYPH cord-015369-72cjogxz 3869 6 nine nine CD cord-015369-72cjogxz 3869 7 colon colon NN cord-015369-72cjogxz 3869 8 and and CC cord-015369-72cjogxz 3869 9 75 75 CD cord-015369-72cjogxz 3869 10 rectal rectal JJ cord-015369-72cjogxz 3869 11 surgeries surgery NNS cord-015369-72cjogxz 3869 12 were be VBD cord-015369-72cjogxz 3869 13 surveyed survey VBN cord-015369-72cjogxz 3869 14 . . . cord-015369-72cjogxz 3870 1 SSI SSI NNP cord-015369-72cjogxz 3870 2 rate rate NN cord-015369-72cjogxz 3870 3 for for IN cord-015369-72cjogxz 3870 4 colon colon NN cord-015369-72cjogxz 3870 5 surgery surgery NN cord-015369-72cjogxz 3870 6 was be VBD cord-015369-72cjogxz 3870 7 17.8 17.8 CD cord-015369-72cjogxz 3870 8 % % NN cord-015369-72cjogxz 3870 9 8 8 CD cord-015369-72cjogxz 3870 10 % % NN cord-015369-72cjogxz 3870 11 ) ) -RRB- cord-015369-72cjogxz 3870 12 . . . cord-015369-72cjogxz 3871 1 SSI SSI NNP cord-015369-72cjogxz 3871 2 rate rate NN cord-015369-72cjogxz 3871 3 after after IN cord-015369-72cjogxz 3871 4 properly properly RB cord-015369-72cjogxz 3871 5 timed time VBN cord-015369-72cjogxz 3871 6 antibiotic antibiotic JJ cord-015369-72cjogxz 3871 7 prophylaxis prophylaxis NN cord-015369-72cjogxz 3871 8 ( ( -LRB- cord-015369-72cjogxz 3871 9 30 30 CD cord-015369-72cjogxz 3871 10 - - SYM cord-015369-72cjogxz 3871 11 60 60 CD cord-015369-72cjogxz 3871 12 min min NNP cord-015369-72cjogxz 3871 13 pre·op pre·op NNP cord-015369-72cjogxz 3871 14 ) ) -RRB- cord-015369-72cjogxz 3871 15 was be VBD cord-015369-72cjogxz 3871 16 9.5 9.5 CD cord-015369-72cjogxz 3871 17 % % NN cord-015369-72cjogxz 3871 18 ( ( -LRB- cord-015369-72cjogxz 3871 19 5.1 5.1 CD cord-015369-72cjogxz 3871 20 - - SYM cord-015369-72cjogxz 3871 21 17.0 17.0 CD cord-015369-72cjogxz 3871 22 % % NN cord-015369-72cjogxz 3871 23 ) ) -RRB- cord-015369-72cjogxz 3871 24 . . . cord-015369-72cjogxz 3872 1 Otherwise otherwise RB cord-015369-72cjogxz 3872 2 the the DT cord-015369-72cjogxz 3872 3 rate rate NN cord-015369-72cjogxz 3872 4 was be VBD cord-015369-72cjogxz 3872 5 significantly significantly RB cord-015369-72cjogxz 3872 6 increased increase VBN cord-015369-72cjogxz 3872 7 : : : cord-015369-72cjogxz 3872 8 > > SYM cord-015369-72cjogxz 3872 9 60 60 CD cord-015369-72cjogxz 3872 10 min min NN cord-015369-72cjogxz 3872 11 pre·op pre·op JJ cord-015369-72cjogxz 3872 12 ¼ ¼ CD cord-015369-72cjogxz 3872 13 27.9 27.9 CD cord-015369-72cjogxz 3872 14 % % NN cord-015369-72cjogxz 3872 15 ( ( -LRB- cord-015369-72cjogxz 3872 16 18.6 18.6 CD cord-015369-72cjogxz 3872 17 - - SYM cord-015369-72cjogxz 3872 18 45.1 45.1 CD cord-015369-72cjogxz 3872 19 % % NN cord-015369-72cjogxz 3872 20 ) ) -RRB- cord-015369-72cjogxz 3872 21 , , , cord-015369-72cjogxz 3872 22 < < XX cord-015369-72cjogxz 3872 23 30 30 CD cord-015369-72cjogxz 3872 24 min min NNP cord-015369-72cjogxz 3872 25 pre·op pre·op JJ cord-015369-72cjogxz 3872 26 ¼ ¼ CD cord-015369-72cjogxz 3872 27 16.0 16.0 CD cord-015369-72cjogxz 3872 28 % % NN cord-015369-72cjogxz 3872 29 ( ( -LRB- cord-015369-72cjogxz 3872 30 8.3 8.3 CD cord-015369-72cjogxz 3872 31 - - HYPH cord-015369-72cjogxz 3872 32 28.5 28.5 CD cord-015369-72cjogxz 3872 33 % % NN cord-015369-72cjogxz 3872 34 ) ) -RRB- cord-015369-72cjogxz 3872 35 or or CC cord-015369-72cjogxz 3872 36 no no DT cord-015369-72cjogxz 3872 37 prophylaxis prophylaxis NN cord-015369-72cjogxz 3872 38 ¼ ¼ NNP cord-015369-72cjogxz 3872 39 43 43 CD cord-015369-72cjogxz 3872 40 . . . cord-015369-72cjogxz 3873 1 8 8 CD cord-015369-72cjogxz 3873 2 % % NN cord-015369-72cjogxz 3873 3 ( ( -LRB- cord-015369-72cjogxz 3873 4 23.1 23.1 CD cord-015369-72cjogxz 3873 5 - - SYM cord-015369-72cjogxz 3873 6 66.8 66.8 CD cord-015369-72cjogxz 3873 7 % % NN cord-015369-72cjogxz 3873 8 ) ) -RRB- cord-015369-72cjogxz 3873 9 ( ( -LRB- cord-015369-72cjogxz 3873 10 mainly mainly RB cord-015369-72cjogxz 3873 11 due due JJ cord-015369-72cjogxz 3873 12 to to IN cord-015369-72cjogxz 3873 13 antibiotic antibiotic JJ cord-015369-72cjogxz 3873 14 treatment treatment NN cord-015369-72cjogxz 3873 15 before before IN cord-015369-72cjogxz 3873 16 surgery surgery NN cord-015369-72cjogxz 3873 17 ) ) -RRB- cord-015369-72cjogxz 3873 18 . . . cord-015369-72cjogxz 3874 1 Higher high JJR cord-015369-72cjogxz 3874 2 BMI bmi NN cord-015369-72cjogxz 3874 3 or or CC cord-015369-72cjogxz 3874 4 body body NN cord-015369-72cjogxz 3874 5 surface surface NN cord-015369-72cjogxz 3874 6 were be VBD cord-015369-72cjogxz 3874 7 linked link VBN cord-015369-72cjogxz 3874 8 with with IN cord-015369-72cjogxz 3874 9 a a DT cord-015369-72cjogxz 3874 10 higher high JJR cord-015369-72cjogxz 3874 11 infection infection NN cord-015369-72cjogxz 3874 12 rate rate NN cord-015369-72cjogxz 3874 13 ( ( -LRB- cord-015369-72cjogxz 3874 14 BMI BMI NNP cord-015369-72cjogxz 3874 15 < < XX cord-015369-72cjogxz 3874 16 24 24 CD cord-015369-72cjogxz 3874 17 ¼ ¼ CD cord-015369-72cjogxz 3874 18 7.3 7.3 CD cord-015369-72cjogxz 3874 19 % % NN cord-015369-72cjogxz 3874 20 , , , cord-015369-72cjogxz 3874 21 ! ! . cord-015369-72cjogxz 3875 1 24 24 CD cord-015369-72cjogxz 3875 2 ¼ ¼ CD cord-015369-72cjogxz 3875 3 21.5 21.5 CD cord-015369-72cjogxz 3875 4 % % NN cord-015369-72cjogxz 3875 5 , , , cord-015369-72cjogxz 3875 6 p p NN cord-015369-72cjogxz 3875 7 ¼ ¼ CD cord-015369-72cjogxz 3875 8 0.02 0.02 CD cord-015369-72cjogxz 3875 9 , , , cord-015369-72cjogxz 3875 10 body body NN cord-015369-72cjogxz 3875 11 surface surface NN cord-015369-72cjogxz 3875 12 < < XX cord-015369-72cjogxz 3875 13 1.7 1.7 CD cord-015369-72cjogxz 3875 14 m m CD cord-015369-72cjogxz 3875 15 2 2 CD cord-015369-72cjogxz 3875 16 ¼ ¼ CD cord-015369-72cjogxz 3875 17 7.2 7.2 CD cord-015369-72cjogxz 3875 18 % % NN cord-015369-72cjogxz 3875 19 , , , cord-015369-72cjogxz 3875 20 ! ! . cord-015369-72cjogxz 3876 1 1.7 1.7 CD cord-015369-72cjogxz 3876 2 m m CD cord-015369-72cjogxz 3876 3 2 2 CD cord-015369-72cjogxz 3876 4 21.6 21.6 CD cord-015369-72cjogxz 3876 5 % % NN cord-015369-72cjogxz 3876 6 , , , cord-015369-72cjogxz 3876 7 p p NN cord-015369-72cjogxz 3876 8 ¼ ¼ CD cord-015369-72cjogxz 3876 9 0.01 0.01 CD cord-015369-72cjogxz 3876 10 ) ) -RRB- cord-015369-72cjogxz 3876 11 . . . cord-015369-72cjogxz 3877 1 Conclusions conclusion NNS cord-015369-72cjogxz 3877 2 . . . cord-015369-72cjogxz 3878 1 Our -PRON- PRP$ cord-015369-72cjogxz 3878 2 COLO COLO NNP cord-015369-72cjogxz 3878 3 SSI SSI NNP cord-015369-72cjogxz 3878 4 rate rate NN cord-015369-72cjogxz 3878 5 is be VBZ cord-015369-72cjogxz 3878 6 higher high JJR cord-015369-72cjogxz 3878 7 than than IN cord-015369-72cjogxz 3878 8 reported report VBN cord-015369-72cjogxz 3878 9 by by IN cord-015369-72cjogxz 3878 10 NNIS nni NNS cord-015369-72cjogxz 3878 11 ( ( -LRB- cord-015369-72cjogxz 3878 12 5.4 5.4 CD cord-015369-72cjogxz 3878 13 % % NN cord-015369-72cjogxz 3878 14 ) ) -RRB- cord-015369-72cjogxz 3878 15 , , , cord-015369-72cjogxz 3878 16 but but CC cord-015369-72cjogxz 3878 17 similar similar JJ cord-015369-72cjogxz 3878 18 to to IN cord-015369-72cjogxz 3878 19 rates rate NNS cord-015369-72cjogxz 3878 20 obtained obtain VBN cord-015369-72cjogxz 3878 21 under under IN cord-015369-72cjogxz 3878 22 study study NN cord-015369-72cjogxz 3878 23 conditions condition NNS cord-015369-72cjogxz 3878 24 . . . cord-015369-72cjogxz 3879 1 Since since IN cord-015369-72cjogxz 3879 2 data datum NNS cord-015369-72cjogxz 3879 3 contribution contribution NN cord-015369-72cjogxz 3879 4 to to IN cord-015369-72cjogxz 3879 5 NNIS NNIS NNP cord-015369-72cjogxz 3879 6 is be VBZ cord-015369-72cjogxz 3879 7 voluntary voluntary JJ cord-015369-72cjogxz 3879 8 , , , cord-015369-72cjogxz 3879 9 a a DT cord-015369-72cjogxz 3879 10 strong strong JJ cord-015369-72cjogxz 3879 11 bias bias NN cord-015369-72cjogxz 3879 12 can can MD cord-015369-72cjogxz 3879 13 not not RB cord-015369-72cjogxz 3879 14 be be VB cord-015369-72cjogxz 3879 15 excluded exclude VBN cord-015369-72cjogxz 3879 16 . . . cord-015369-72cjogxz 3880 1 Incorrect incorrect JJ cord-015369-72cjogxz 3880 2 timing timing NN cord-015369-72cjogxz 3880 3 of of IN cord-015369-72cjogxz 3880 4 antibiotic antibiotic JJ cord-015369-72cjogxz 3880 5 prophylaxis prophylaxis NN cord-015369-72cjogxz 3880 6 was be VBD cord-015369-72cjogxz 3880 7 the the DT cord-015369-72cjogxz 3880 8 key key JJ cord-015369-72cjogxz 3880 9 risk risk NN cord-015369-72cjogxz 3880 10 factor factor NN cord-015369-72cjogxz 3880 11 for for IN cord-015369-72cjogxz 3880 12 wound wound JJ cord-015369-72cjogxz 3880 13 infections infection NNS cord-015369-72cjogxz 3880 14 . . . cord-015369-72cjogxz 3881 1 Bolus Bolus NNP cord-015369-72cjogxz 3881 2 administration administration NN cord-015369-72cjogxz 3881 3 of of IN cord-015369-72cjogxz 3881 4 antibiotics antibiotic NNS cord-015369-72cjogxz 3881 5 could could MD cord-015369-72cjogxz 3881 6 explain explain VB cord-015369-72cjogxz 3881 7 the the DT cord-015369-72cjogxz 3881 8 influence influence NN cord-015369-72cjogxz 3881 9 of of IN cord-015369-72cjogxz 3881 10 body body NN cord-015369-72cjogxz 3881 11 size size NN cord-015369-72cjogxz 3881 12 on on IN cord-015369-72cjogxz 3881 13 the the DT cord-015369-72cjogxz 3881 14 SSI SSI NNP cord-015369-72cjogxz 3881 15 rate rate NN cord-015369-72cjogxz 3881 16 . . . cord-015369-72cjogxz 3882 1 Patients patient NNS cord-015369-72cjogxz 3882 2 with with IN cord-015369-72cjogxz 3882 3 a a DT cord-015369-72cjogxz 3882 4 big big JJ cord-015369-72cjogxz 3882 5 body body NN cord-015369-72cjogxz 3882 6 size size NN cord-015369-72cjogxz 3882 7 have have VBP cord-015369-72cjogxz 3882 8 a a DT cord-015369-72cjogxz 3882 9 lower low JJR cord-015369-72cjogxz 3882 10 plasma plasma NN cord-015369-72cjogxz 3882 11 concentration concentration NN cord-015369-72cjogxz 3882 12 resulting result VBG cord-015369-72cjogxz 3882 13 in in IN cord-015369-72cjogxz 3882 14 higher high JJR cord-015369-72cjogxz 3882 15 infection infection NN cord-015369-72cjogxz 3882 16 rates rate NNS cord-015369-72cjogxz 3882 17 . . . cord-015369-72cjogxz 3883 1 In in IN cord-015369-72cjogxz 3883 2 summary summary JJ cord-015369-72cjogxz 3883 3 strict strict JJ cord-015369-72cjogxz 3883 4 adherence adherence NN cord-015369-72cjogxz 3883 5 to to IN cord-015369-72cjogxz 3883 6 proper proper JJ cord-015369-72cjogxz 3883 7 timing timing NN cord-015369-72cjogxz 3883 8 of of IN cord-015369-72cjogxz 3883 9 antibiotic antibiotic JJ cord-015369-72cjogxz 3883 10 administration administration NN cord-015369-72cjogxz 3883 11 can can MD cord-015369-72cjogxz 3883 12 drastically drastically RB cord-015369-72cjogxz 3883 13 reduce reduce VB cord-015369-72cjogxz 3883 14 colorectal colorectal JJ cord-015369-72cjogxz 3883 15 SSI SSI NNP cord-015369-72cjogxz 3883 16 rates rate NNS cord-015369-72cjogxz 3883 17 . . . cord-015369-72cjogxz 3884 1 First first JJ cord-015369-72cjogxz 3884 2 experience experience NN cord-015369-72cjogxz 3884 3 about about IN cord-015369-72cjogxz 3884 4 treatment treatment NN cord-015369-72cjogxz 3884 5 of of IN cord-015369-72cjogxz 3884 6 chronic chronic JJ cord-015369-72cjogxz 3884 7 leg leg NN cord-015369-72cjogxz 3884 8 ulcers ulcer NNS cord-015369-72cjogxz 3884 9 using use VBG cord-015369-72cjogxz 3884 10 DUCEST DUCEST NNP cord-015369-72cjogxz 3884 11 ( ( -LRB- cord-015369-72cjogxz 3884 12 Dual dual JJ cord-015369-72cjogxz 3884 13 cell cell NN cord-015369-72cjogxz 3884 14 stimulation stimulation NN cord-015369-72cjogxz 3884 15 ) ) -RRB- cord-015369-72cjogxz 3884 16 therapy therapy NN cord-015369-72cjogxz 3884 17 T. t. NN cord-015369-72cjogxz 3884 18 Payrits Payrits NNP cord-015369-72cjogxz 3884 19 , , , cord-015369-72cjogxz 3884 20 S. S. NNP cord-015369-72cjogxz 3884 21 Viragos Viragos NNP cord-015369-72cjogxz 3884 22 , , , cord-015369-72cjogxz 3884 23 A. a. NN cord-015369-72cjogxz 3884 24 Ernst Ernst NNP cord-015369-72cjogxz 3884 25 , , , cord-015369-72cjogxz 3884 26 G. G. NNP cord-015369-72cjogxz 3884 27 Klein Klein NNP cord-015369-72cjogxz 3884 28 , , , cord-015369-72cjogxz 3884 29 F. F. NNP cord-015369-72cjogxz 3884 30 Längle Längle NNP cord-015369-72cjogxz 3884 31 Background Background NNP cord-015369-72cjogxz 3884 32 . . . cord-015369-72cjogxz 3885 1 Ulcus Ulcus NNP cord-015369-72cjogxz 3885 2 cruris cruris NN cord-015369-72cjogxz 3885 3 describes describe VBZ cord-015369-72cjogxz 3885 4 a a DT cord-015369-72cjogxz 3885 5 complex complex JJ cord-015369-72cjogxz 3885 6 medical medical JJ cord-015369-72cjogxz 3885 7 condition condition NN cord-015369-72cjogxz 3885 8 which which WDT cord-015369-72cjogxz 3885 9 affects affect VBZ cord-015369-72cjogxz 3885 10 the the DT cord-015369-72cjogxz 3885 11 quality quality NN cord-015369-72cjogxz 3885 12 of of IN cord-015369-72cjogxz 3885 13 life life NN cord-015369-72cjogxz 3885 14 of of IN cord-015369-72cjogxz 3885 15 patients patient NNS cord-015369-72cjogxz 3885 16 considerably considerably RB cord-015369-72cjogxz 3885 17 . . . cord-015369-72cjogxz 3886 1 This this DT cord-015369-72cjogxz 3886 2 report report NN cord-015369-72cjogxz 3886 3 refers refer VBZ cord-015369-72cjogxz 3886 4 first first JJ cord-015369-72cjogxz 3886 5 results result NNS cord-015369-72cjogxz 3886 6 about about IN cord-015369-72cjogxz 3886 7 the the DT cord-015369-72cjogxz 3886 8 treatment treatment NN cord-015369-72cjogxz 3886 9 of of IN cord-015369-72cjogxz 3886 10 7 7 CD cord-015369-72cjogxz 3886 11 patients patient NNS cord-015369-72cjogxz 3886 12 with with IN cord-015369-72cjogxz 3886 13 chronic chronic JJ cord-015369-72cjogxz 3886 14 leg leg NN cord-015369-72cjogxz 3886 15 ulcers ulcer NNS cord-015369-72cjogxz 3886 16 with with IN cord-015369-72cjogxz 3886 17 varied varied JJ cord-015369-72cjogxz 3886 18 underlying underlying JJ cord-015369-72cjogxz 3886 19 causes cause NNS cord-015369-72cjogxz 3886 20 . . . cord-015369-72cjogxz 3887 1 Aim aim VB cord-015369-72cjogxz 3887 2 . . . cord-015369-72cjogxz 3888 1 The the DT cord-015369-72cjogxz 3888 2 aim aim NN cord-015369-72cjogxz 3888 3 of of IN cord-015369-72cjogxz 3888 4 this this DT cord-015369-72cjogxz 3888 5 study study NN cord-015369-72cjogxz 3888 6 is be VBZ cord-015369-72cjogxz 3888 7 to to TO cord-015369-72cjogxz 3888 8 achieve achieve VB cord-015369-72cjogxz 3888 9 granulation granulation NN cord-015369-72cjogxz 3888 10 tissue tissue NN cord-015369-72cjogxz 3888 11 by by IN cord-015369-72cjogxz 3888 12 using use VBG cord-015369-72cjogxz 3888 13 endogenous endogenous JJ cord-015369-72cjogxz 3888 14 growth growth NN cord-015369-72cjogxz 3888 15 factors factor NNS cord-015369-72cjogxz 3888 16 and and CC cord-015369-72cjogxz 3888 17 improving improve VBG cord-015369-72cjogxz 3888 18 wound wound NN cord-015369-72cjogxz 3888 19 perfusion perfusion NN cord-015369-72cjogxz 3888 20 , , , cord-015369-72cjogxz 3888 21 where where WRB cord-015369-72cjogxz 3888 22 other other JJ cord-015369-72cjogxz 3888 23 methods method NNS cord-015369-72cjogxz 3888 24 failed fail VBD cord-015369-72cjogxz 3888 25 . . . cord-015369-72cjogxz 3889 1 The the DT cord-015369-72cjogxz 3889 2 DUCEST DUCEST NNP cord-015369-72cjogxz 3889 3 therapy therapy NN cord-015369-72cjogxz 3889 4 associates associate VBZ cord-015369-72cjogxz 3889 5 the the DT cord-015369-72cjogxz 3889 6 application application NN cord-015369-72cjogxz 3889 7 of of IN cord-015369-72cjogxz 3889 8 PRF PRF NNP cord-015369-72cjogxz 3889 9 ( ( -LRB- cord-015369-72cjogxz 3889 10 platelet platelet JJ cord-015369-72cjogxz 3889 11 rich rich JJ cord-015369-72cjogxz 3889 12 fibrin fibrin NN cord-015369-72cjogxz 3889 13 ) ) -RRB- cord-015369-72cjogxz 3889 14 with with IN cord-015369-72cjogxz 3889 15 targeted target VBN cord-015369-72cjogxz 3889 16 stimulation stimulation NN cord-015369-72cjogxz 3889 17 of of IN cord-015369-72cjogxz 3889 18 the the DT cord-015369-72cjogxz 3889 19 vagal vagal JJ cord-015369-72cjogxz 3889 20 nerv nerv NN cord-015369-72cjogxz 3889 21 to to TO cord-015369-72cjogxz 3889 22 encourage encourage VB cord-015369-72cjogxz 3889 23 peripheral peripheral JJ cord-015369-72cjogxz 3889 24 blood blood NN cord-015369-72cjogxz 3889 25 flow flow NN cord-015369-72cjogxz 3889 26 by by IN cord-015369-72cjogxz 3889 27 use use NN cord-015369-72cjogxz 3889 28 of of IN cord-015369-72cjogxz 3889 29 P p NN cord-015369-72cjogxz 3889 30 - - HYPH cord-015369-72cjogxz 3889 31 STIM STIM NNP cord-015369-72cjogxz 3889 32 . . . cord-015369-72cjogxz 3890 1 Methods method NNS cord-015369-72cjogxz 3890 2 . . . cord-015369-72cjogxz 3891 1 PRF PRF NNP cord-015369-72cjogxz 3891 2 combines combine VBZ cord-015369-72cjogxz 3891 3 autologous autologous JJ cord-015369-72cjogxz 3891 4 fibrin fibrin NN cord-015369-72cjogxz 3891 5 sealant sealant NN cord-015369-72cjogxz 3891 6 and and CC cord-015369-72cjogxz 3891 7 platelets platelet NNS cord-015369-72cjogxz 3891 8 . . . cord-015369-72cjogxz 3892 1 This this DT cord-015369-72cjogxz 3892 2 biomatrix biomatrix NN cord-015369-72cjogxz 3892 3 protects protect VBZ cord-015369-72cjogxz 3892 4 endogenous endogenous JJ cord-015369-72cjogxz 3892 5 growth growth NN cord-015369-72cjogxz 3892 6 factors factor NNS cord-015369-72cjogxz 3892 7 against against IN cord-015369-72cjogxz 3892 8 proteolytic proteolytic JJ cord-015369-72cjogxz 3892 9 degradation degradation NN cord-015369-72cjogxz 3892 10 and and CC cord-015369-72cjogxz 3892 11 thereby thereby RB cord-015369-72cjogxz 3892 12 preserves preserve VBZ cord-015369-72cjogxz 3892 13 their -PRON- PRP$ cord-015369-72cjogxz 3892 14 biological biological JJ cord-015369-72cjogxz 3892 15 activity activity NN cord-015369-72cjogxz 3892 16 . . . cord-015369-72cjogxz 3893 1 We -PRON- PRP cord-015369-72cjogxz 3893 2 draw draw VBP cord-015369-72cjogxz 3893 3 120 120 CD cord-015369-72cjogxz 3893 4 ml ml NN cord-015369-72cjogxz 3893 5 blood blood NN cord-015369-72cjogxz 3893 6 from from IN cord-015369-72cjogxz 3893 7 the the DT cord-015369-72cjogxz 3893 8 patient patient NN cord-015369-72cjogxz 3893 9 to to TO cord-015369-72cjogxz 3893 10 gain gain VB cord-015369-72cjogxz 3893 11 6 6 CD cord-015369-72cjogxz 3893 12 ml ml NN cord-015369-72cjogxz 3893 13 PRF PRF NNP cord-015369-72cjogxz 3893 14 solution solution NN cord-015369-72cjogxz 3893 15 . . . cord-015369-72cjogxz 3894 1 We -PRON- PRP cord-015369-72cjogxz 3894 2 apply apply VBP cord-015369-72cjogxz 3894 3 the the DT cord-015369-72cjogxz 3894 4 PRF PRF NNP cord-015369-72cjogxz 3894 5 - - HYPH cord-015369-72cjogxz 3894 6 biomatrix biomatrix NN cord-015369-72cjogxz 3894 7 with with IN cord-015369-72cjogxz 3894 8 a a DT cord-015369-72cjogxz 3894 9 Spraypen Spraypen NNP cord-015369-72cjogxz 3894 10 provided provide VBN cord-015369-72cjogxz 3894 11 by by IN cord-015369-72cjogxz 3894 12 Vivostat Vivostat NNP cord-015369-72cjogxz 3894 13 . . . cord-015369-72cjogxz 3895 1 For for IN cord-015369-72cjogxz 3895 2 patients patient NNS cord-015369-72cjogxz 3895 3 with with IN cord-015369-72cjogxz 3895 4 ulcus ulcus NNP cord-015369-72cjogxz 3895 5 cruris cruris NNP cord-015369-72cjogxz 3895 6 who who WP cord-015369-72cjogxz 3895 7 have have VBP cord-015369-72cjogxz 3895 8 an an DT cord-015369-72cjogxz 3895 9 impaired impaired JJ cord-015369-72cjogxz 3895 10 blood blood NN cord-015369-72cjogxz 3895 11 flow flow NN cord-015369-72cjogxz 3895 12 in in IN cord-015369-72cjogxz 3895 13 the the DT cord-015369-72cjogxz 3895 14 wound wound NN cord-015369-72cjogxz 3895 15 , , , cord-015369-72cjogxz 3895 16 we -PRON- PRP cord-015369-72cjogxz 3895 17 use use VBP cord-015369-72cjogxz 3895 18 P p NN cord-015369-72cjogxz 3895 19 - - HYPH cord-015369-72cjogxz 3895 20 STIM STIM NNP cord-015369-72cjogxz 3895 21 to to TO cord-015369-72cjogxz 3895 22 improve improve VB cord-015369-72cjogxz 3895 23 circulation circulation NN cord-015369-72cjogxz 3895 24 in in IN cord-015369-72cjogxz 3895 25 the the DT cord-015369-72cjogxz 3895 26 limbs limb NNS cord-015369-72cjogxz 3895 27 . . . cord-015369-72cjogxz 3896 1 The the DT cord-015369-72cjogxz 3896 2 P p NN cord-015369-72cjogxz 3896 3 - - HYPH cord-015369-72cjogxz 3896 4 STIM STIM NNP cord-015369-72cjogxz 3896 5 is be VBZ cord-015369-72cjogxz 3896 6 a a DT cord-015369-72cjogxz 3896 7 miniaturized miniaturized JJ cord-015369-72cjogxz 3896 8 device device NN cord-015369-72cjogxz 3896 9 designed design VBN cord-015369-72cjogxz 3896 10 to to TO cord-015369-72cjogxz 3896 11 administer administer VB cord-015369-72cjogxz 3896 12 auriculo auriculo JJ cord-015369-72cjogxz 3896 13 point point NN cord-015369-72cjogxz 3896 14 stimulation stimulation NN cord-015369-72cjogxz 3896 15 treatment treatment NN cord-015369-72cjogxz 3896 16 over over IN cord-015369-72cjogxz 3896 17 several several JJ cord-015369-72cjogxz 3896 18 days day NNS cord-015369-72cjogxz 3896 19 . . . cord-015369-72cjogxz 3897 1 The the DT cord-015369-72cjogxz 3897 2 mobility mobility NN cord-015369-72cjogxz 3897 3 of of IN cord-015369-72cjogxz 3897 4 the the DT cord-015369-72cjogxz 3897 5 patient patient NN cord-015369-72cjogxz 3897 6 is be VBZ cord-015369-72cjogxz 3897 7 a a DT cord-015369-72cjogxz 3897 8 main main JJ cord-015369-72cjogxz 3897 9 benefit benefit NN cord-015369-72cjogxz 3897 10 of of IN cord-015369-72cjogxz 3897 11 this this DT cord-015369-72cjogxz 3897 12 therapy therapy NN cord-015369-72cjogxz 3897 13 . . . cord-015369-72cjogxz 3898 1 Results result NNS cord-015369-72cjogxz 3898 2 . . . cord-015369-72cjogxz 3899 1 So so RB cord-015369-72cjogxz 3899 2 far far RB cord-015369-72cjogxz 3899 3 we -PRON- PRP cord-015369-72cjogxz 3899 4 treated treat VBD cord-015369-72cjogxz 3899 5 7 7 CD cord-015369-72cjogxz 3899 6 patients patient NNS cord-015369-72cjogxz 3899 7 with with IN cord-015369-72cjogxz 3899 8 refractory refractory JJ cord-015369-72cjogxz 3899 9 ulceras ulcera NNS cord-015369-72cjogxz 3899 10 . . . cord-015369-72cjogxz 3900 1 6 6 CD cord-015369-72cjogxz 3900 2 patients patient NNS cord-015369-72cjogxz 3900 3 achieved achieve VBN cord-015369-72cjogxz 3900 4 wound wind VBN cord-015369-72cjogxz 3900 5 healing healing NN cord-015369-72cjogxz 3900 6 or or CC cord-015369-72cjogxz 3900 7 a a DT cord-015369-72cjogxz 3900 8 clear clear JJ cord-015369-72cjogxz 3900 9 improvement improvement NN cord-015369-72cjogxz 3900 10 of of IN cord-015369-72cjogxz 3900 11 their -PRON- PRP$ cord-015369-72cjogxz 3900 12 wound wound NN cord-015369-72cjogxz 3900 13 situation situation NN cord-015369-72cjogxz 3900 14 . . . cord-015369-72cjogxz 3901 1 In in IN cord-015369-72cjogxz 3901 2 one one CD cord-015369-72cjogxz 3901 3 patient patient NN cord-015369-72cjogxz 3901 4 we -PRON- PRP cord-015369-72cjogxz 3901 5 could could MD cord-015369-72cjogxz 3901 6 stop stop VB cord-015369-72cjogxz 3901 7 the the DT cord-015369-72cjogxz 3901 8 worsening worsening NN cord-015369-72cjogxz 3901 9 of of IN cord-015369-72cjogxz 3901 10 the the DT cord-015369-72cjogxz 3901 11 ulcer ulcer NN cord-015369-72cjogxz 3901 12 . . . cord-015369-72cjogxz 3902 1 The the DT cord-015369-72cjogxz 3902 2 lack lack NN cord-015369-72cjogxz 3902 3 of of IN cord-015369-72cjogxz 3902 4 woundhealing woundheale VBG cord-015369-72cjogxz 3902 5 in in IN cord-015369-72cjogxz 3902 6 that that DT cord-015369-72cjogxz 3902 7 case case NN cord-015369-72cjogxz 3902 8 was be VBD cord-015369-72cjogxz 3902 9 due due JJ cord-015369-72cjogxz 3902 10 to to IN cord-015369-72cjogxz 3902 11 the the DT cord-015369-72cjogxz 3902 12 non non JJ cord-015369-72cjogxz 3902 13 compliance compliance NN cord-015369-72cjogxz 3902 14 of of IN cord-015369-72cjogxz 3902 15 the the DT cord-015369-72cjogxz 3902 16 patient patient NN cord-015369-72cjogxz 3902 17 . . . cord-015369-72cjogxz 3903 1 Conclusions conclusion NNS cord-015369-72cjogxz 3903 2 . . . cord-015369-72cjogxz 3904 1 Based base VBN cord-015369-72cjogxz 3904 2 on on IN cord-015369-72cjogxz 3904 3 these these DT cord-015369-72cjogxz 3904 4 favorable favorable JJ cord-015369-72cjogxz 3904 5 findings finding NNS cord-015369-72cjogxz 3904 6 we -PRON- PRP cord-015369-72cjogxz 3904 7 will will MD cord-015369-72cjogxz 3904 8 evaluate evaluate VB cord-015369-72cjogxz 3904 9 the the DT cord-015369-72cjogxz 3904 10 DUCEST DUCEST NNP cord-015369-72cjogxz 3904 11 therapy therapy NN cord-015369-72cjogxz 3904 12 in in IN cord-015369-72cjogxz 3904 13 a a DT cord-015369-72cjogxz 3904 14 prospective prospective JJ cord-015369-72cjogxz 3904 15 study study NN cord-015369-72cjogxz 3904 16 . . . cord-015369-72cjogxz 3905 1 Background background NN cord-015369-72cjogxz 3905 2 . . . cord-015369-72cjogxz 3906 1 Endo Endo NNP cord-015369-72cjogxz 3906 2 - - HYPH cord-015369-72cjogxz 3906 3 Vacuum Vacuum NNP cord-015369-72cjogxz 3906 4 assisted assist VBD cord-015369-72cjogxz 3906 5 treatment treatment NN cord-015369-72cjogxz 3907 1 ( ( -LRB- cord-015369-72cjogxz 3907 2 Endo Endo NNP cord-015369-72cjogxz 3907 3 - - HYPH cord-015369-72cjogxz 3907 4 Vac Vac NNP cord-015369-72cjogxz 3907 5 ) ) -RRB- cord-015369-72cjogxz 3907 6 represents represent VBZ cord-015369-72cjogxz 3907 7 a a DT cord-015369-72cjogxz 3907 8 novel novel JJ cord-015369-72cjogxz 3907 9 approach approach NN cord-015369-72cjogxz 3907 10 to to TO cord-015369-72cjogxz 3907 11 treat treat VB cord-015369-72cjogxz 3907 12 patients patient NNS cord-015369-72cjogxz 3907 13 with with IN cord-015369-72cjogxz 3907 14 anastomotic anastomotic JJ cord-015369-72cjogxz 3907 15 dehiscence dehiscence NN cord-015369-72cjogxz 3907 16 following follow VBG cord-015369-72cjogxz 3907 17 anterior anterior JJ cord-015369-72cjogxz 3907 18 resection resection NN cord-015369-72cjogxz 3907 19 for for IN cord-015369-72cjogxz 3907 20 rectal rectal JJ cord-015369-72cjogxz 3907 21 surgery surgery NN cord-015369-72cjogxz 3907 22 . . . cord-015369-72cjogxz 3908 1 Yet yet RB cord-015369-72cjogxz 3908 2 , , , cord-015369-72cjogxz 3908 3 limited limited JJ cord-015369-72cjogxz 3908 4 data datum NNS cord-015369-72cjogxz 3908 5 are be VBP cord-015369-72cjogxz 3908 6 available available JJ cord-015369-72cjogxz 3908 7 to to TO cord-015369-72cjogxz 3908 8 predict predict VB cord-015369-72cjogxz 3908 9 success success NN cord-015369-72cjogxz 3908 10 , , , cord-015369-72cjogxz 3908 11 compatibility compatibility NN cord-015369-72cjogxz 3908 12 with with IN cord-015369-72cjogxz 3908 13 radio radio NN cord-015369-72cjogxz 3908 14 - - HYPH cord-015369-72cjogxz 3908 15 and and CC cord-015369-72cjogxz 3908 16 / / SYM cord-015369-72cjogxz 3908 17 or or CC cord-015369-72cjogxz 3908 18 chemotherapy chemotherapy NN cord-015369-72cjogxz 3908 19 as as RB cord-015369-72cjogxz 3908 20 well well RB cord-015369-72cjogxz 3908 21 as as IN cord-015369-72cjogxz 3908 22 acceptance acceptance NN cord-015369-72cjogxz 3908 23 by by IN cord-015369-72cjogxz 3908 24 the the DT cord-015369-72cjogxz 3908 25 patients patient NNS cord-015369-72cjogxz 3908 26 . . . cord-015369-72cjogxz 3909 1 Methods method NNS cord-015369-72cjogxz 3909 2 . . . cord-015369-72cjogxz 3910 1 Between between IN cord-015369-72cjogxz 3910 2 September September NNP cord-015369-72cjogxz 3910 3 2007 2007 CD cord-015369-72cjogxz 3910 4 and and CC cord-015369-72cjogxz 3910 5 June June NNP cord-015369-72cjogxz 3910 6 2008 2008 CD cord-015369-72cjogxz 3910 7 9 9 CD cord-015369-72cjogxz 3910 8 patients patient NNS cord-015369-72cjogxz 3910 9 suffering suffer VBG cord-015369-72cjogxz 3910 10 from from IN cord-015369-72cjogxz 3910 11 anastomotic anastomotic JJ cord-015369-72cjogxz 3910 12 leakage leakage NN cord-015369-72cjogxz 3910 13 after after IN cord-015369-72cjogxz 3910 14 anterior anterior JJ cord-015369-72cjogxz 3910 15 rectal rectal JJ cord-015369-72cjogxz 3910 16 resection resection NN cord-015369-72cjogxz 3910 17 ( ( -LRB- cord-015369-72cjogxz 3910 18 n n NN cord-015369-72cjogxz 3910 19 ¼ ¼ NNP cord-015369-72cjogxz 3910 20 6 6 CD cord-015369-72cjogxz 3910 21 ) ) -RRB- cord-015369-72cjogxz 3910 22 or or CC cord-015369-72cjogxz 3910 23 suffering suffer VBG cord-015369-72cjogxz 3910 24 from from IN cord-015369-72cjogxz 3910 25 leakage leakage NN cord-015369-72cjogxz 3910 26 of of IN cord-015369-72cjogxz 3910 27 rectal rectal JJ cord-015369-72cjogxz 3910 28 stump stump NN cord-015369-72cjogxz 3910 29 following follow VBG cord-015369-72cjogxz 3910 30 Hartmann Hartmann NNP cord-015369-72cjogxz 3910 31 's 's POS cord-015369-72cjogxz 3910 32 procedure procedure NN cord-015369-72cjogxz 3910 33 ( ( -LRB- cord-015369-72cjogxz 3910 34 n n NN cord-015369-72cjogxz 3910 35 ¼ ¼ NNP cord-015369-72cjogxz 3910 36 3 3 CD cord-015369-72cjogxz 3910 37 ) ) -RRB- cord-015369-72cjogxz 3910 38 were be VBD cord-015369-72cjogxz 3910 39 treated treat VBN cord-015369-72cjogxz 3910 40 by by IN cord-015369-72cjogxz 3910 41 Endo Endo NNP cord-015369-72cjogxz 3910 42 - - HYPH cord-015369-72cjogxz 3910 43 Vac Vac NNP cord-015369-72cjogxz 3910 44 . . . cord-015369-72cjogxz 3911 1 We -PRON- PRP cord-015369-72cjogxz 3911 2 recorded record VBD cord-015369-72cjogxz 3911 3 clinical clinical JJ cord-015369-72cjogxz 3911 4 outcome outcome NN cord-015369-72cjogxz 3911 5 and and CC cord-015369-72cjogxz 3911 6 patient patient NN cord-015369-72cjogxz 3911 7 's 's POS cord-015369-72cjogxz 3911 8 comfort comfort NN cord-015369-72cjogxz 3911 9 using use VBG cord-015369-72cjogxz 3911 10 a a DT cord-015369-72cjogxz 3911 11 ten ten CD cord-015369-72cjogxz 3911 12 point point NN cord-015369-72cjogxz 3911 13 visual visual JJ cord-015369-72cjogxz 3911 14 analogue analogue NN cord-015369-72cjogxz 3911 15 scale scale NN cord-015369-72cjogxz 3911 16 ( ( -LRB- cord-015369-72cjogxz 3911 17 VAS VAS NNP cord-015369-72cjogxz 3911 18 ) ) -RRB- cord-015369-72cjogxz 3911 19 . . . cord-015369-72cjogxz 3912 1 Results result NNS cord-015369-72cjogxz 3912 2 . . . cord-015369-72cjogxz 3913 1 Median median JJ cord-015369-72cjogxz 3913 2 time time NN cord-015369-72cjogxz 3913 3 of of IN cord-015369-72cjogxz 3913 4 Endo Endo NNP cord-015369-72cjogxz 3913 5 - - HYPH cord-015369-72cjogxz 3913 6 Vac Vac NNP cord-015369-72cjogxz 3913 7 treatment treatment NN cord-015369-72cjogxz 3913 8 was be VBD cord-015369-72cjogxz 3913 9 3 3 CD cord-015369-72cjogxz 3913 10 weeks week NNS cord-015369-72cjogxz 3914 1 ( ( -LRB- cord-015369-72cjogxz 3914 2 range range NN cord-015369-72cjogxz 3914 3 , , , cord-015369-72cjogxz 3914 4 2 2 CD cord-015369-72cjogxz 3914 5 - - SYM cord-015369-72cjogxz 3914 6 8 8 CD cord-015369-72cjogxz 3914 7 ) ) -RRB- cord-015369-72cjogxz 3914 8 . . . cord-015369-72cjogxz 3915 1 There there EX cord-015369-72cjogxz 3915 2 were be VBD cord-015369-72cjogxz 3915 3 no no DT cord-015369-72cjogxz 3915 4 minor minor JJ cord-015369-72cjogxz 3915 5 or or CC cord-015369-72cjogxz 3915 6 major major JJ cord-015369-72cjogxz 3915 7 complications complication NNS cord-015369-72cjogxz 3915 8 . . . cord-015369-72cjogxz 3916 1 In in IN cord-015369-72cjogxz 3916 2 6 6 CD cord-015369-72cjogxz 3916 3 ( ( -LRB- cord-015369-72cjogxz 3916 4 66.6 66.6 CD cord-015369-72cjogxz 3916 5 percent percent NN cord-015369-72cjogxz 3916 6 ) ) -RRB- cord-015369-72cjogxz 3916 7 patients patient NNS cord-015369-72cjogxz 3916 8 the the DT cord-015369-72cjogxz 3916 9 anastomotic anastomotic JJ cord-015369-72cjogxz 3916 10 leakage leakage NN cord-015369-72cjogxz 3916 11 healed heal VBN cord-015369-72cjogxz 3916 12 successfully successfully RB cord-015369-72cjogxz 3916 13 . . . cord-015369-72cjogxz 3917 1 Three three CD cord-015369-72cjogxz 3917 2 patients patient NNS cord-015369-72cjogxz 3917 3 showed show VBD cord-015369-72cjogxz 3917 4 no no DT cord-015369-72cjogxz 3917 5 response response NN cord-015369-72cjogxz 3917 6 and and CC cord-015369-72cjogxz 3917 7 needed need VBD cord-015369-72cjogxz 3917 8 further further JJ cord-015369-72cjogxz 3917 9 surgical surgical JJ cord-015369-72cjogxz 3917 10 intervention intervention NN cord-015369-72cjogxz 3917 11 . . . cord-015369-72cjogxz 3918 1 The the DT cord-015369-72cjogxz 3918 2 lack lack NN cord-015369-72cjogxz 3918 3 of of IN cord-015369-72cjogxz 3918 4 success success NN cord-015369-72cjogxz 3918 5 was be VBD cord-015369-72cjogxz 3918 6 due due JJ cord-015369-72cjogxz 3918 7 to to IN cord-015369-72cjogxz 3918 8 complexity complexity NN cord-015369-72cjogxz 3918 9 of of IN cord-015369-72cjogxz 3918 10 leakages leakage NNS cord-015369-72cjogxz 3918 11 , , , cord-015369-72cjogxz 3918 12 which which WDT cord-015369-72cjogxz 3918 13 comprised comprise VBD cord-015369-72cjogxz 3918 14 either either CC cord-015369-72cjogxz 3918 15 more more JJR cord-015369-72cjogxz 3918 16 than than IN cord-015369-72cjogxz 3918 17 270 270 CD cord-015369-72cjogxz 3918 18 degree degree NN cord-015369-72cjogxz 3918 19 of of IN cord-015369-72cjogxz 3918 20 the the DT cord-015369-72cjogxz 3918 21 circumference circumference NN cord-015369-72cjogxz 3918 22 or or CC cord-015369-72cjogxz 3918 23 consisted consist VBD cord-015369-72cjogxz 3918 24 of of IN cord-015369-72cjogxz 3918 25 2 2 CD cord-015369-72cjogxz 3918 26 distant distant JJ cord-015369-72cjogxz 3918 27 fistulas fistula NNS cord-015369-72cjogxz 3918 28 . . . cord-015369-72cjogxz 3919 1 Formation formation NN cord-015369-72cjogxz 3919 2 of of IN cord-015369-72cjogxz 3919 3 granulation granulation NN cord-015369-72cjogxz 3919 4 tissue tissue NN cord-015369-72cjogxz 3919 5 was be VBD cord-015369-72cjogxz 3919 6 unaffected unaffected JJ cord-015369-72cjogxz 3919 7 by by IN cord-015369-72cjogxz 3919 8 chemotherapy chemotherapy NN cord-015369-72cjogxz 3919 9 . . . cord-015369-72cjogxz 3920 1 For for IN cord-015369-72cjogxz 3920 2 the the DT cord-015369-72cjogxz 3920 3 question question NN cord-015369-72cjogxz 3920 4 ' ' '' cord-015369-72cjogxz 3920 5 ' ' '' cord-015369-72cjogxz 3920 6 alteration alteration NN cord-015369-72cjogxz 3920 7 in in IN cord-015369-72cjogxz 3920 8 daily daily JJ cord-015369-72cjogxz 3920 9 life life NN cord-015369-72cjogxz 3920 10 activity activity NN cord-015369-72cjogxz 3920 11 ' ' '' cord-015369-72cjogxz 3920 12 ' ' '' cord-015369-72cjogxz 3920 13 a a DT cord-015369-72cjogxz 3920 14 median median JJ cord-015369-72cjogxz 3920 15 score score NN cord-015369-72cjogxz 3920 16 of of IN cord-015369-72cjogxz 3920 17 5 5 CD cord-015369-72cjogxz 3920 18 ( ( -LRB- cord-015369-72cjogxz 3920 19 range range NN cord-015369-72cjogxz 3920 20 , , , cord-015369-72cjogxz 3920 21 1 1 CD cord-015369-72cjogxz 3920 22 - - SYM cord-015369-72cjogxz 3920 23 9 9 CD cord-015369-72cjogxz 3920 24 ) ) -RRB- cord-015369-72cjogxz 3920 25 was be VBD cord-015369-72cjogxz 3920 26 found find VBN cord-015369-72cjogxz 3920 27 . . . cord-015369-72cjogxz 3921 1 Measuring measure VBG cord-015369-72cjogxz 3921 2 ' ' POS cord-015369-72cjogxz 3921 3 ' ' `` cord-015369-72cjogxz 3921 4 pain pain NN cord-015369-72cjogxz 3921 5 sensation sensation NN cord-015369-72cjogxz 3921 6 ' ' '' cord-015369-72cjogxz 3921 7 ' ' '' cord-015369-72cjogxz 3922 1 during during IN cord-015369-72cjogxz 3922 2 End end NN cord-015369-72cjogxz 3922 3 - - HYPH cord-015369-72cjogxz 3922 4 Vac vac NN cord-015369-72cjogxz 3922 5 treatment treatment NN cord-015369-72cjogxz 3922 6 patients patient NNS cord-015369-72cjogxz 3922 7 scored score VBD cord-015369-72cjogxz 3922 8 a a DT cord-015369-72cjogxz 3922 9 median median NN cord-015369-72cjogxz 3922 10 of of IN cord-015369-72cjogxz 3922 11 3 3 CD cord-015369-72cjogxz 3922 12 ( ( -LRB- cord-015369-72cjogxz 3922 13 range range NN cord-015369-72cjogxz 3922 14 , , , cord-015369-72cjogxz 3922 15 0 0 CD cord-015369-72cjogxz 3922 16 - - SYM cord-015369-72cjogxz 3922 17 6 6 CD cord-015369-72cjogxz 3922 18 ) ) -RRB- cord-015369-72cjogxz 3922 19 . . . cord-015369-72cjogxz 3923 1 Conclusions conclusion NNS cord-015369-72cjogxz 3923 2 . . . cord-015369-72cjogxz 3924 1 Endo endo NN cord-015369-72cjogxz 3924 2 - - HYPH cord-015369-72cjogxz 3924 3 Vac vac NN cord-015369-72cjogxz 3924 4 treatment treatment NN cord-015369-72cjogxz 3924 5 can can MD cord-015369-72cjogxz 3924 6 be be VB cord-015369-72cjogxz 3924 7 recommended recommend VBN cord-015369-72cjogxz 3924 8 as as IN cord-015369-72cjogxz 3924 9 an an DT cord-015369-72cjogxz 3924 10 alternative alternative JJ cord-015369-72cjogxz 3924 11 approach approach NN cord-015369-72cjogxz 3924 12 to to TO cord-015369-72cjogxz 3924 13 treat treat VB cord-015369-72cjogxz 3924 14 pelvic pelvic JJ cord-015369-72cjogxz 3924 15 sepsis sepsis NN cord-015369-72cjogxz 3924 16 following follow VBG cord-015369-72cjogxz 3924 17 anastomotic anastomotic JJ cord-015369-72cjogxz 3924 18 dehiscence dehiscence NN cord-015369-72cjogxz 3924 19 or or CC cord-015369-72cjogxz 3924 20 rectal rectal JJ cord-015369-72cjogxz 3924 21 stump stump NN cord-015369-72cjogxz 3924 22 insufficiency insufficiency NN cord-015369-72cjogxz 3924 23 . . . cord-015369-72cjogxz 3925 1 Extended extended JJ cord-015369-72cjogxz 3925 2 leakages leakage NNS cord-015369-72cjogxz 3925 3 should should MD cord-015369-72cjogxz 3925 4 be be VB cord-015369-72cjogxz 3925 5 treated treat VBN cord-015369-72cjogxz 3925 6 by by IN cord-015369-72cjogxz 3925 7 different different JJ cord-015369-72cjogxz 3925 8 approaches approach NNS cord-015369-72cjogxz 3925 9 having have VBG cord-015369-72cjogxz 3925 10 little little JJ cord-015369-72cjogxz 3925 11 probability probability NN cord-015369-72cjogxz 3925 12 of of IN cord-015369-72cjogxz 3925 13 successful successful JJ cord-015369-72cjogxz 3925 14 healing healing NN cord-015369-72cjogxz 3925 15 but but CC cord-015369-72cjogxz 3925 16 can can MD cord-015369-72cjogxz 3925 17 lead lead VB cord-015369-72cjogxz 3925 18 to to IN cord-015369-72cjogxz 3925 19 discomfort discomfort NN cord-015369-72cjogxz 3925 20 for for IN cord-015369-72cjogxz 3925 21 the the DT cord-015369-72cjogxz 3925 22 patient patient NN cord-015369-72cjogxz 3925 23 . . . cord-015369-72cjogxz 3926 1 Radiochemotherapy Radiochemotherapy NNP cord-015369-72cjogxz 3926 2 does do VBZ cord-015369-72cjogxz 3926 3 not not RB cord-015369-72cjogxz 3926 4 cause cause VB cord-015369-72cjogxz 3926 5 a a DT cord-015369-72cjogxz 3926 6 problem problem NN cord-015369-72cjogxz 3926 7 for for IN cord-015369-72cjogxz 3926 8 application application NN cord-015369-72cjogxz 3926 9 of of IN cord-015369-72cjogxz 3926 10 the the DT cord-015369-72cjogxz 3926 11 Endo Endo NNP cord-015369-72cjogxz 3926 12 - - HYPH cord-015369-72cjogxz 3926 13 Vac Vac NNP cord-015369-72cjogxz 3926 14 . . . cord-015369-72cjogxz 3927 1 Background background NN cord-015369-72cjogxz 3927 2 . . . cord-015369-72cjogxz 3928 1 Carcinoid carcinoid NN cord-015369-72cjogxz 3928 2 tumors tumor NNS cord-015369-72cjogxz 3928 3 of of IN cord-015369-72cjogxz 3928 4 the the DT cord-015369-72cjogxz 3928 5 vermiform vermiform NNP cord-015369-72cjogxz 3928 6 appendix appendix NNP cord-015369-72cjogxz 3928 7 are be VBP cord-015369-72cjogxz 3928 8 reported report VBN cord-015369-72cjogxz 3928 9 to to TO cord-015369-72cjogxz 3928 10 be be VB cord-015369-72cjogxz 3928 11 a a DT cord-015369-72cjogxz 3928 12 rare rare JJ cord-015369-72cjogxz 3928 13 occasion occasion NN cord-015369-72cjogxz 3928 14 and and CC cord-015369-72cjogxz 3928 15 to to TO cord-015369-72cjogxz 3928 16 contribute contribute VB cord-015369-72cjogxz 3928 17 to to IN cord-015369-72cjogxz 3928 18 classical classical JJ cord-015369-72cjogxz 3928 19 ' ' '' cord-015369-72cjogxz 3928 20 ' ' `` cord-015369-72cjogxz 3928 21 carcinoid carcinoid NN cord-015369-72cjogxz 3928 22 syndrome syndrome NN cord-015369-72cjogxz 3928 23 ' ' '' cord-015369-72cjogxz 3928 24 ' ' '' cord-015369-72cjogxz 3928 25 only only RB cord-015369-72cjogxz 3928 26 in in IN cord-015369-72cjogxz 3928 27 the the DT cord-015369-72cjogxz 3928 28 case case NN cord-015369-72cjogxz 3928 29 of of IN cord-015369-72cjogxz 3928 30 distant distant JJ cord-015369-72cjogxz 3928 31 spread spread NN cord-015369-72cjogxz 3928 32 . . . cord-015369-72cjogxz 3929 1 However however RB cord-015369-72cjogxz 3929 2 , , , cord-015369-72cjogxz 3929 3 these these DT cord-015369-72cjogxz 3929 4 tumors tumor NNS cord-015369-72cjogxz 3929 5 may may MD cord-015369-72cjogxz 3929 6 present present VB cord-015369-72cjogxz 3929 7 clinical clinical JJ cord-015369-72cjogxz 3929 8 signs sign NNS cord-015369-72cjogxz 3929 9 even even RB cord-015369-72cjogxz 3929 10 in in IN cord-015369-72cjogxz 3929 11 absence absence NN cord-015369-72cjogxz 3929 12 of of IN cord-015369-72cjogxz 3929 13 metastases metastasis NNS cord-015369-72cjogxz 3929 14 . . . cord-015369-72cjogxz 3930 1 Methods method NNS cord-015369-72cjogxz 3930 2 . . . cord-015369-72cjogxz 3931 1 One one CD cord-015369-72cjogxz 3931 2 hundred hundred CD cord-015369-72cjogxz 3931 3 thirthy thirthy NNP cord-015369-72cjogxz 3932 1 one one CD cord-015369-72cjogxz 3932 2 appendix appendix NNP cord-015369-72cjogxz 3932 3 carcinoids carcinoids NNPS cord-015369-72cjogxz 3932 4 were be VBD cord-015369-72cjogxz 3932 5 identified identify VBN cord-015369-72cjogxz 3932 6 out out IN cord-015369-72cjogxz 3932 7 of of IN cord-015369-72cjogxz 3932 8 more more JJR cord-015369-72cjogxz 3932 9 than than IN cord-015369-72cjogxz 3932 10 500,000 500,000 CD cord-015369-72cjogxz 3932 11 histological histological JJ cord-015369-72cjogxz 3932 12 specimen specimen NN cord-015369-72cjogxz 3932 13 , , , cord-015369-72cjogxz 3932 14 i.e. i.e. FW cord-015369-72cjogxz 3932 15 in in IN cord-015369-72cjogxz 3932 16 0.5 0.5 CD cord-015369-72cjogxz 3932 17 % % NN cord-015369-72cjogxz 3932 18 of of IN cord-015369-72cjogxz 3932 19 all all DT cord-015369-72cjogxz 3932 20 appendectomies appendectomy NNS cord-015369-72cjogxz 3932 21 . . . cord-015369-72cjogxz 3933 1 Six six CD cord-015369-72cjogxz 3933 2 ( ( -LRB- cord-015369-72cjogxz 3933 3 4.6 4.6 CD cord-015369-72cjogxz 3933 4 % % NN cord-015369-72cjogxz 3933 5 ) ) -RRB- cord-015369-72cjogxz 3933 6 were be VBD cord-015369-72cjogxz 3933 7 found find VBN cord-015369-72cjogxz 3933 8 at at IN cord-015369-72cjogxz 3933 9 colonic colonic JJ cord-015369-72cjogxz 3933 10 resection resection NN cord-015369-72cjogxz 3933 11 for for IN cord-015369-72cjogxz 3933 12 caecal caecal JJ cord-015369-72cjogxz 3933 13 carcinoma carcinoma NN cord-015369-72cjogxz 3933 14 and and CC cord-015369-72cjogxz 3933 15 angiodysplastic angiodysplastic JJ cord-015369-72cjogxz 3933 16 syndrome syndrome NN cord-015369-72cjogxz 3933 17 . . . cord-015369-72cjogxz 3934 1 All all DT cord-015369-72cjogxz 3934 2 patients patient NNS cord-015369-72cjogxz 3934 3 were be VBD cord-015369-72cjogxz 3934 4 operated operate VBN cord-015369-72cjogxz 3934 5 for for IN cord-015369-72cjogxz 3934 6 the the DT cord-015369-72cjogxz 3934 7 the the DT cord-015369-72cjogxz 3934 8 clinical clinical JJ cord-015369-72cjogxz 3934 9 signs sign NNS cord-015369-72cjogxz 3934 10 of of IN cord-015369-72cjogxz 3934 11 acute acute JJ cord-015369-72cjogxz 3934 12 or or CC cord-015369-72cjogxz 3934 13 chronic chronic JJ cord-015369-72cjogxz 3934 14 appendicitis appendicitis NN cord-015369-72cjogxz 3934 15 . . . cord-015369-72cjogxz 3935 1 All all DT cord-015369-72cjogxz 3935 2 carcinoid carcinoid NN cord-015369-72cjogxz 3935 3 tumors tumor NNS cord-015369-72cjogxz 3935 4 were be VBD cord-015369-72cjogxz 3935 5 revised revise VBN cord-015369-72cjogxz 3935 6 retrospectively retrospectively RB cord-015369-72cjogxz 3935 7 for for IN cord-015369-72cjogxz 3935 8 their -PRON- PRP$ cord-015369-72cjogxz 3935 9 medical medical JJ cord-015369-72cjogxz 3935 10 history history NN cord-015369-72cjogxz 3935 11 . . . cord-015369-72cjogxz 3936 1 Results result NNS cord-015369-72cjogxz 3936 2 . . . cord-015369-72cjogxz 3937 1 52/131 52/131 CD cord-015369-72cjogxz 3937 2 ( ( -LRB- cord-015369-72cjogxz 3938 1 39.6 39.6 CD cord-015369-72cjogxz 3938 2 % % NN cord-015369-72cjogxz 3938 3 ) ) -RRB- cord-015369-72cjogxz 3938 4 cases case NNS cord-015369-72cjogxz 3938 5 were be VBD cord-015369-72cjogxz 3938 6 found find VBN cord-015369-72cjogxz 3938 7 in in IN cord-015369-72cjogxz 3938 8 combination combination NN cord-015369-72cjogxz 3938 9 with with IN cord-015369-72cjogxz 3938 10 acute acute JJ cord-015369-72cjogxz 3938 11 inflammation inflammation NN cord-015369-72cjogxz 3938 12 of of IN cord-015369-72cjogxz 3938 13 the the DT cord-015369-72cjogxz 3938 14 appendix appendix NN cord-015369-72cjogxz 3938 15 , , , cord-015369-72cjogxz 3938 16 but but CC cord-015369-72cjogxz 3938 17 79/131 79/131 CD cord-015369-72cjogxz 3938 18 ( ( -LRB- cord-015369-72cjogxz 3938 19 60.4 60.4 CD cord-015369-72cjogxz 3938 20 % % NN cord-015369-72cjogxz 3938 21 ) ) -RRB- cord-015369-72cjogxz 3938 22 did do VBD cord-015369-72cjogxz 3938 23 not not RB cord-015369-72cjogxz 3938 24 show show VB cord-015369-72cjogxz 3938 25 pathological pathological JJ cord-015369-72cjogxz 3938 26 findings finding NNS cord-015369-72cjogxz 3938 27 except except IN cord-015369-72cjogxz 3938 28 the the DT cord-015369-72cjogxz 3938 29 endocrine endocrine JJ cord-015369-72cjogxz 3938 30 tumor tumor NN cord-015369-72cjogxz 3938 31 . . . cord-015369-72cjogxz 3939 1 Almost almost RB cord-015369-72cjogxz 3939 2 all all DT cord-015369-72cjogxz 3939 3 had have VBD cord-015369-72cjogxz 3939 4 hormones hormone NNS cord-015369-72cjogxz 3939 5 of of IN cord-015369-72cjogxz 3939 6 the the DT cord-015369-72cjogxz 3939 7 midgut midgut NN cord-015369-72cjogxz 3939 8 group group NN cord-015369-72cjogxz 3939 9 as as IN cord-015369-72cjogxz 3939 10 Serotonin Serotonin NNP cord-015369-72cjogxz 3939 11 , , , cord-015369-72cjogxz 3939 12 NSE NSE NNP cord-015369-72cjogxz 3939 13 and and CC cord-015369-72cjogxz 3939 14 Chromogranin Chromogranin NNP cord-015369-72cjogxz 3939 15 A A NNP cord-015369-72cjogxz 3939 16 in in IN cord-015369-72cjogxz 3939 17 immunochemistry immunochemistry NN cord-015369-72cjogxz 3939 18 , , , cord-015369-72cjogxz 3939 19 only only RB cord-015369-72cjogxz 3939 20 one one CD cord-015369-72cjogxz 3939 21 case case NN cord-015369-72cjogxz 3939 22 expressed express VBD cord-015369-72cjogxz 3939 23 ACTH ACTH NNP cord-015369-72cjogxz 3940 1 Most Most JJS cord-015369-72cjogxz 3940 2 tumors tumor NNS cord-015369-72cjogxz 3940 3 were be VBD cord-015369-72cjogxz 3940 4 located locate VBN cord-015369-72cjogxz 3940 5 in in IN cord-015369-72cjogxz 3940 6 the the DT cord-015369-72cjogxz 3940 7 tip tip NN cord-015369-72cjogxz 3940 8 ( ( -LRB- cord-015369-72cjogxz 3940 9 76.8 76.8 CD cord-015369-72cjogxz 3940 10 % % NN cord-015369-72cjogxz 3940 11 ) ) -RRB- cord-015369-72cjogxz 3940 12 , , , cord-015369-72cjogxz 3940 13 only only RB cord-015369-72cjogxz 3940 14 10 10 CD cord-015369-72cjogxz 3940 15 % % NN cord-015369-72cjogxz 3940 16 infiltrated infiltrate VBD cord-015369-72cjogxz 3940 17 the the DT cord-015369-72cjogxz 3940 18 mesenteriolum mesenteriolum NN cord-015369-72cjogxz 3940 19 or or CC cord-015369-72cjogxz 3940 20 penetrated penetrate VBD cord-015369-72cjogxz 3940 21 the the DT cord-015369-72cjogxz 3940 22 serosa serosa NNP cord-015369-72cjogxz 3940 23 . . . cord-015369-72cjogxz 3941 1 When when WRB cord-015369-72cjogxz 3941 2 the the DT cord-015369-72cjogxz 3941 3 endocrine endocrine JJ cord-015369-72cjogxz 3941 4 parameters parameter NNS cord-015369-72cjogxz 3941 5 ( ( -LRB- cord-015369-72cjogxz 3941 6 Serotonin Serotonin NNS cord-015369-72cjogxz 3941 7 . . . cord-015369-72cjogxz 3942 1 Chrom Chrom NNP cord-015369-72cjogxz 3942 2 ogranin ogranin NNS cord-015369-72cjogxz 3942 3 A a NN cord-015369-72cjogxz 3942 4 ) ) -RRB- cord-015369-72cjogxz 3942 5 were be VBD cord-015369-72cjogxz 3942 6 determined determine VBN cord-015369-72cjogxz 3942 7 preoperatively preoperatively NN cord-015369-72cjogxz 3942 8 in in IN cord-015369-72cjogxz 3942 9 a a DT cord-015369-72cjogxz 3942 10 group group NN cord-015369-72cjogxz 3942 11 of of IN cord-015369-72cjogxz 3942 12 127 127 CD cord-015369-72cjogxz 3942 13 cases case NNS cord-015369-72cjogxz 3942 14 , , , cord-015369-72cjogxz 3942 15 we -PRON- PRP cord-015369-72cjogxz 3942 16 failed fail VBD cord-015369-72cjogxz 3942 17 to to TO cord-015369-72cjogxz 3942 18 establish establish VB cord-015369-72cjogxz 3942 19 elevated elevated JJ cord-015369-72cjogxz 3942 20 serum serum NN cord-015369-72cjogxz 3942 21 levels level NNS cord-015369-72cjogxz 3942 22 in in IN cord-015369-72cjogxz 3942 23 the the DT cord-015369-72cjogxz 3942 24 presence presence NN cord-015369-72cjogxz 3942 25 of of IN cord-015369-72cjogxz 3942 26 an an DT cord-015369-72cjogxz 3942 27 carcinoid carcinoid NN cord-015369-72cjogxz 3942 28 tumor tumor NN cord-015369-72cjogxz 3942 29 . . . cord-015369-72cjogxz 3943 1 Conclusions conclusion NNS cord-015369-72cjogxz 3943 2 . . . cord-015369-72cjogxz 3944 1 Only only RB cord-015369-72cjogxz 3944 2 fourty fourty CD cord-015369-72cjogxz 3944 3 per per IN cord-015369-72cjogxz 3944 4 cent cent NN cord-015369-72cjogxz 3944 5 of of IN cord-015369-72cjogxz 3944 6 appendix appendix NNP cord-015369-72cjogxz 3944 7 carcinoids carcinoids NNP cord-015369-72cjogxz 3944 8 present present JJ cord-015369-72cjogxz 3944 9 in in IN cord-015369-72cjogxz 3944 10 combination combination NN cord-015369-72cjogxz 3944 11 with with IN cord-015369-72cjogxz 3944 12 acute acute JJ cord-015369-72cjogxz 3944 13 inflammation inflammation NN cord-015369-72cjogxz 3944 14 and and CC cord-015369-72cjogxz 3944 15 are be VBP cord-015369-72cjogxz 3944 16 ' ' `` cord-015369-72cjogxz 3944 17 ' ' `` cord-015369-72cjogxz 3944 18 incidental incidental JJ cord-015369-72cjogxz 3944 19 findings finding NNS cord-015369-72cjogxz 3944 20 ' ' POS cord-015369-72cjogxz 3944 21 ' ' '' cord-015369-72cjogxz 3944 22 in in IN cord-015369-72cjogxz 3944 23 appendectomy appendectomy NN cord-015369-72cjogxz 3944 24 . . . cord-015369-72cjogxz 3945 1 Sixty sixty NN cord-015369-72cjogxz 3945 2 per per IN cord-015369-72cjogxz 3945 3 cent cent NN cord-015369-72cjogxz 3945 4 present present NN cord-015369-72cjogxz 3945 5 with with IN cord-015369-72cjogxz 3945 6 typical typical JJ cord-015369-72cjogxz 3945 7 signs sign NNS cord-015369-72cjogxz 3945 8 of of IN cord-015369-72cjogxz 3945 9 appendicits appendicit NNS cord-015369-72cjogxz 3945 10 but but CC cord-015369-72cjogxz 3945 11 without without IN cord-015369-72cjogxz 3945 12 any any DT cord-015369-72cjogxz 3945 13 histological histological JJ cord-015369-72cjogxz 3945 14 proof proof NN cord-015369-72cjogxz 3945 15 of of IN cord-015369-72cjogxz 3945 16 inflammation inflammation NN cord-015369-72cjogxz 3945 17 . . . cord-015369-72cjogxz 3946 1 So so RB cord-015369-72cjogxz 3946 2 the the DT cord-015369-72cjogxz 3946 3 endocrine endocrine JJ cord-015369-72cjogxz 3946 4 tumor tumor NN cord-015369-72cjogxz 3946 5 causes cause VBZ cord-015369-72cjogxz 3946 6 clinical clinical JJ cord-015369-72cjogxz 3946 7 symptomes symptome NNS cord-015369-72cjogxz 3946 8 per per FW cord-015369-72cjogxz 3946 9 se se FW cord-015369-72cjogxz 3946 10 besides besides IN cord-015369-72cjogxz 3946 11 carcinoid carcinoid NN cord-015369-72cjogxz 3946 12 syndrome syndrome NN cord-015369-72cjogxz 3946 13 . . . cord-015369-72cjogxz 3947 1 Background background NN cord-015369-72cjogxz 3947 2 . . . cord-015369-72cjogxz 3948 1 NET net NN cord-015369-72cjogxz 3948 2 of of IN cord-015369-72cjogxz 3948 3 the the DT cord-015369-72cjogxz 3948 4 appendix appendix NN cord-015369-72cjogxz 3948 5 makes make VBZ cord-015369-72cjogxz 3948 6 a a DT cord-015369-72cjogxz 3948 7 part part NN cord-015369-72cjogxz 3948 8 of of IN cord-015369-72cjogxz 3948 9 17 17 CD cord-015369-72cjogxz 3948 10 % % NN cord-015369-72cjogxz 3948 11 of of IN cord-015369-72cjogxz 3948 12 all all DT cord-015369-72cjogxz 3948 13 gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 3948 14 NET net NN cord-015369-72cjogxz 3948 15 . . . cord-015369-72cjogxz 3949 1 They -PRON- PRP cord-015369-72cjogxz 3949 2 mostly mostly RB cord-015369-72cjogxz 3949 3 appear appear VBP cord-015369-72cjogxz 3949 4 in in IN cord-015369-72cjogxz 3949 5 younger young JJR cord-015369-72cjogxz 3949 6 people people NNS cord-015369-72cjogxz 3949 7 and and CC cord-015369-72cjogxz 3949 8 major major JJ cord-015369-72cjogxz 3949 9 part part NN cord-015369-72cjogxz 3949 10 is be VBZ cord-015369-72cjogxz 3949 11 benign benign JJ cord-015369-72cjogxz 3949 12 , , , cord-015369-72cjogxz 3949 13 because because IN cord-015369-72cjogxz 3949 14 of of IN cord-015369-72cjogxz 3949 15 little little JJ cord-015369-72cjogxz 3949 16 diameter diameter NN cord-015369-72cjogxz 3949 17 and and CC cord-015369-72cjogxz 3949 18 leak leak NN cord-015369-72cjogxz 3949 19 of of IN cord-015369-72cjogxz 3949 20 hormon hormon NN cord-015369-72cjogxz 3949 21 production production NN cord-015369-72cjogxz 3949 22 . . . cord-015369-72cjogxz 3950 1 If if IN cord-015369-72cjogxz 3950 2 diameter diameter NN cord-015369-72cjogxz 3950 3 is be VBZ cord-015369-72cjogxz 3950 4 about about RB cord-015369-72cjogxz 3950 5 2 2 CD cord-015369-72cjogxz 3950 6 centimetres centimetre NNS cord-015369-72cjogxz 3950 7 or or CC cord-015369-72cjogxz 3950 8 above above RB cord-015369-72cjogxz 3950 9 , , , cord-015369-72cjogxz 3950 10 patients patient NNS cord-015369-72cjogxz 3950 11 are be VBP cord-015369-72cjogxz 3950 12 running run VBG cord-015369-72cjogxz 3950 13 a a DT cord-015369-72cjogxz 3950 14 significant significant JJ cord-015369-72cjogxz 3950 15 risk risk NN cord-015369-72cjogxz 3950 16 to to TO cord-015369-72cjogxz 3950 17 produce produce VB cord-015369-72cjogxz 3950 18 distant distant JJ cord-015369-72cjogxz 3950 19 metastasis metastasis NN cord-015369-72cjogxz 3950 20 , , , cord-015369-72cjogxz 3950 21 generally generally RB cord-015369-72cjogxz 3950 22 without without IN cord-015369-72cjogxz 3950 23 a a DT cord-015369-72cjogxz 3950 24 carcinoid carcinoid NN cord-015369-72cjogxz 3950 25 syndrome syndrome NN cord-015369-72cjogxz 3950 26 . . . cord-015369-72cjogxz 3951 1 The the DT cord-015369-72cjogxz 3951 2 recently recently RB cord-015369-72cjogxz 3951 3 discussed discuss VBN cord-015369-72cjogxz 3951 4 entity entity NN cord-015369-72cjogxz 3951 5 is be VBZ cord-015369-72cjogxz 3951 6 the the DT cord-015369-72cjogxz 3951 7 goblet goblet NN cord-015369-72cjogxz 3951 8 cell cell NN cord-015369-72cjogxz 3951 9 carcinoid carcinoid NN cord-015369-72cjogxz 3951 10 ( ( -LRB- cord-015369-72cjogxz 3951 11 GCC GCC NNP cord-015369-72cjogxz 3951 12 ) ) -RRB- cord-015369-72cjogxz 3951 13 , , , cord-015369-72cjogxz 3951 14 whose whose WP$ cord-015369-72cjogxz 3951 15 existence existence NN cord-015369-72cjogxz 3951 16 is be VBZ cord-015369-72cjogxz 3951 17 to to TO cord-015369-72cjogxz 3951 18 accentuate accentuate VB cord-015369-72cjogxz 3951 19 , , , cord-015369-72cjogxz 3951 20 because because IN cord-015369-72cjogxz 3951 21 of of IN cord-015369-72cjogxz 3951 22 the the DT cord-015369-72cjogxz 3951 23 necessity necessity NN cord-015369-72cjogxz 3951 24 to to TO cord-015369-72cjogxz 3951 25 treat treat VB cord-015369-72cjogxz 3951 26 them -PRON- PRP cord-015369-72cjogxz 3951 27 like like IN cord-015369-72cjogxz 3951 28 an an DT cord-015369-72cjogxz 3951 29 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 3951 30 . . . cord-015369-72cjogxz 3952 1 Methods method NNS cord-015369-72cjogxz 3952 2 . . . cord-015369-72cjogxz 3953 1 From from IN cord-015369-72cjogxz 3953 2 1988 1988 CD cord-015369-72cjogxz 3953 3 to to IN cord-015369-72cjogxz 3953 4 2008 2008 CD cord-015369-72cjogxz 3953 5 we -PRON- PRP cord-015369-72cjogxz 3953 6 have have VBP cord-015369-72cjogxz 3953 7 done do VBN cord-015369-72cjogxz 3953 8 4936 4936 CD cord-015369-72cjogxz 3953 9 appendectomies appendectomy NNS cord-015369-72cjogxz 3953 10 . . . cord-015369-72cjogxz 3954 1 0.3 0.3 CD cord-015369-72cjogxz 3954 2 percent percent NN cord-015369-72cjogxz 3954 3 or or CC cord-015369-72cjogxz 3954 4 16 16 CD cord-015369-72cjogxz 3954 5 patients patient NNS cord-015369-72cjogxz 3954 6 had have VBD cord-015369-72cjogxz 3954 7 a a DT cord-015369-72cjogxz 3954 8 NET net NN cord-015369-72cjogxz 3954 9 of of IN cord-015369-72cjogxz 3954 10 the the DT cord-015369-72cjogxz 3954 11 appendix appendix NN cord-015369-72cjogxz 3954 12 . . . cord-015369-72cjogxz 3955 1 Mean mean JJ cord-015369-72cjogxz 3955 2 age age NN cord-015369-72cjogxz 3955 3 was be VBD cord-015369-72cjogxz 3955 4 41 41 CD cord-015369-72cjogxz 3955 5 years year NNS cord-015369-72cjogxz 3955 6 , , , cord-015369-72cjogxz 3955 7 10 10 CD cord-015369-72cjogxz 3955 8 men man NNS cord-015369-72cjogxz 3955 9 in in IN cord-015369-72cjogxz 3955 10 proportion proportion NN cord-015369-72cjogxz 3955 11 to to IN cord-015369-72cjogxz 3955 12 6 6 CD cord-015369-72cjogxz 3955 13 women woman NNS cord-015369-72cjogxz 3955 14 . . . cord-015369-72cjogxz 3956 1 Most Most JJS cord-015369-72cjogxz 3956 2 part part NN cord-015369-72cjogxz 3956 3 ( ( -LRB- cord-015369-72cjogxz 3956 4 n n NN cord-015369-72cjogxz 3956 5 ¼ ¼ NNP cord-015369-72cjogxz 3956 6 9 9 CD cord-015369-72cjogxz 3956 7 ) ) -RRB- cord-015369-72cjogxz 3956 8 had have VBD cord-015369-72cjogxz 3956 9 surgery surgery NN cord-015369-72cjogxz 3956 10 because because IN cord-015369-72cjogxz 3956 11 of of IN cord-015369-72cjogxz 3956 12 acute acute JJ cord-015369-72cjogxz 3956 13 appendicitis appendicitis NN cord-015369-72cjogxz 3956 14 . . . cord-015369-72cjogxz 3957 1 Only only RB cord-015369-72cjogxz 3957 2 five five CD cord-015369-72cjogxz 3957 3 patients patient NNS cord-015369-72cjogxz 3957 4 described describe VBD cord-015369-72cjogxz 3957 5 a a DT cord-015369-72cjogxz 3957 6 long long JJ cord-015369-72cjogxz 3957 7 period period NN cord-015369-72cjogxz 3957 8 of of IN cord-015369-72cjogxz 3957 9 pain pain NN cord-015369-72cjogxz 3957 10 with with IN cord-015369-72cjogxz 3957 11 cramps cramp NNS cord-015369-72cjogxz 3957 12 and and CC cord-015369-72cjogxz 3957 13 diarrhoe diarrhoe NNS cord-015369-72cjogxz 3957 14 . . . cord-015369-72cjogxz 3958 1 Most Most JJS cord-015369-72cjogxz 3958 2 part part NN cord-015369-72cjogxz 3958 3 ( ( -LRB- cord-015369-72cjogxz 3958 4 n n NN cord-015369-72cjogxz 3958 5 ¼ ¼ NNP cord-015369-72cjogxz 3958 6 12 12 CD cord-015369-72cjogxz 3958 7 ) ) -RRB- cord-015369-72cjogxz 3958 8 of of IN cord-015369-72cjogxz 3958 9 NET NET NNP cord-015369-72cjogxz 3958 10 was be VBD cord-015369-72cjogxz 3958 11 located locate VBN cord-015369-72cjogxz 3958 12 at at IN cord-015369-72cjogxz 3958 13 the the DT cord-015369-72cjogxz 3958 14 tip tip NN cord-015369-72cjogxz 3958 15 of of IN cord-015369-72cjogxz 3958 16 the the DT cord-015369-72cjogxz 3958 17 appendix appendix NN cord-015369-72cjogxz 3958 18 with with IN cord-015369-72cjogxz 3958 19 a a DT cord-015369-72cjogxz 3958 20 diameter diameter NN cord-015369-72cjogxz 3958 21 range range NN cord-015369-72cjogxz 3958 22 from from IN cord-015369-72cjogxz 3958 23 2 2 CD cord-015369-72cjogxz 3958 24 to to IN cord-015369-72cjogxz 3958 25 18 18 CD cord-015369-72cjogxz 3958 26 mm mm NNS cord-015369-72cjogxz 3958 27 . . . cord-015369-72cjogxz 3959 1 Results result NNS cord-015369-72cjogxz 3959 2 . . . cord-015369-72cjogxz 3960 1 NET NET NNP cord-015369-72cjogxz 3960 2 was be VBD cord-015369-72cjogxz 3960 3 never never RB cord-015369-72cjogxz 3960 4 diagnosed diagnose VBN cord-015369-72cjogxz 3960 5 intraoperatively intraoperatively NN cord-015369-72cjogxz 3960 6 , , , cord-015369-72cjogxz 3960 7 although although IN cord-015369-72cjogxz 3960 8 50 50 CD cord-015369-72cjogxz 3960 9 % % NN cord-015369-72cjogxz 3960 10 of of IN cord-015369-72cjogxz 3960 11 appendectomies appendectomy NNS cord-015369-72cjogxz 3960 12 have have VBP cord-015369-72cjogxz 3960 13 been be VBN cord-015369-72cjogxz 3960 14 done do VBN cord-015369-72cjogxz 3960 15 by by IN cord-015369-72cjogxz 3960 16 specialists specialist NNS cord-015369-72cjogxz 3960 17 in in IN cord-015369-72cjogxz 3960 18 surgery surgery NN cord-015369-72cjogxz 3960 19 . . . cord-015369-72cjogxz 3961 1 In in IN cord-015369-72cjogxz 3961 2 two two CD cord-015369-72cjogxz 3961 3 cases case NNS cord-015369-72cjogxz 3961 4 right right JJ cord-015369-72cjogxz 3961 5 hemicolectomy hemicolectomy NN cord-015369-72cjogxz 3961 6 was be VBD cord-015369-72cjogxz 3961 7 done do VBN cord-015369-72cjogxz 3961 8 primary primary JJ cord-015369-72cjogxz 3961 9 because because IN cord-015369-72cjogxz 3961 10 of of IN cord-015369-72cjogxz 3961 11 an an DT cord-015369-72cjogxz 3961 12 ileus ileus NN cord-015369-72cjogxz 3961 13 , , , cord-015369-72cjogxz 3961 14 in in IN cord-015369-72cjogxz 3961 15 four four CD cord-015369-72cjogxz 3961 16 cases case NNS cord-015369-72cjogxz 3961 17 it -PRON- PRP cord-015369-72cjogxz 3961 18 was be VBD cord-015369-72cjogxz 3961 19 done do VBN cord-015369-72cjogxz 3961 20 secondary secondary JJ cord-015369-72cjogxz 3961 21 , , , cord-015369-72cjogxz 3961 22 belonging belong VBG cord-015369-72cjogxz 3961 23 to to IN cord-015369-72cjogxz 3961 24 tumor tumor NN cord-015369-72cjogxz 3961 25 size size NN cord-015369-72cjogxz 3961 26 , , , cord-015369-72cjogxz 3961 27 patients patient NNS cord-015369-72cjogxz 3961 28 age age NN cord-015369-72cjogxz 3961 29 and and CC cord-015369-72cjogxz 3961 30 GCC gcc NN cord-015369-72cjogxz 3961 31 . . . cord-015369-72cjogxz 3962 1 Only only RB cord-015369-72cjogxz 3962 2 one one CD cord-015369-72cjogxz 3962 3 patient patient NN cord-015369-72cjogxz 3962 4 showed show VBD cord-015369-72cjogxz 3962 5 metastatic metastatic JJ cord-015369-72cjogxz 3962 6 disease disease NN cord-015369-72cjogxz 3962 7 , , , cord-015369-72cjogxz 3962 8 when when WRB cord-015369-72cjogxz 3962 9 having have VBG cord-015369-72cjogxz 3962 10 done do VBN cord-015369-72cjogxz 3962 11 a a DT cord-015369-72cjogxz 3962 12 second second JJ cord-015369-72cjogxz 3962 13 look look NN cord-015369-72cjogxz 3962 14 . . . cord-015369-72cjogxz 3963 1 All all DT cord-015369-72cjogxz 3963 2 NET NET NNP cord-015369-72cjogxz 3963 3 's 's POS cord-015369-72cjogxz 3963 4 immunehistochemically immunehistochemically NN cord-015369-72cjogxz 3963 5 showed show VBD cord-015369-72cjogxz 3963 6 an an DT cord-015369-72cjogxz 3963 7 expression expression NN cord-015369-72cjogxz 3963 8 of of IN cord-015369-72cjogxz 3963 9 Chromogranin Chromogranin NNP cord-015369-72cjogxz 3963 10 A A NNP cord-015369-72cjogxz 3963 11 and and CC cord-015369-72cjogxz 3963 12 Synaptophysin Synaptophysin NNP cord-015369-72cjogxz 3963 13 . . . cord-015369-72cjogxz 3964 1 Conclusions conclusion NNS cord-015369-72cjogxz 3964 2 . . . cord-015369-72cjogxz 3965 1 Although although IN cord-015369-72cjogxz 3965 2 diagnose diagnose NN cord-015369-72cjogxz 3965 3 of of IN cord-015369-72cjogxz 3965 4 NET net NN cord-015369-72cjogxz 3965 5 was be VBD cord-015369-72cjogxz 3965 6 not not RB cord-015369-72cjogxz 3965 7 known know VBN cord-015369-72cjogxz 3965 8 when when WRB cord-015369-72cjogxz 3965 9 doing do VBG cord-015369-72cjogxz 3965 10 appendectomy appendectomy NN cord-015369-72cjogxz 3965 11 , , , cord-015369-72cjogxz 3965 12 prognosis prognosis NN cord-015369-72cjogxz 3965 13 of of IN cord-015369-72cjogxz 3965 14 patients patient NNS cord-015369-72cjogxz 3965 15 outcome outcome NN cord-015369-72cjogxz 3965 16 was be VBD cord-015369-72cjogxz 3965 17 not not RB cord-015369-72cjogxz 3965 18 influenced influence VBN cord-015369-72cjogxz 3965 19 in in IN cord-015369-72cjogxz 3965 20 a a DT cord-015369-72cjogxz 3965 21 negative negative JJ cord-015369-72cjogxz 3965 22 way way NN cord-015369-72cjogxz 3965 23 . . . cord-015369-72cjogxz 3966 1 Why why WRB cord-015369-72cjogxz 3966 2 have have VBP cord-015369-72cjogxz 3966 3 neuroendocrine neuroendocrine JJ cord-015369-72cjogxz 3966 4 tumors tumor NNS cord-015369-72cjogxz 3966 5 ( ( -LRB- cord-015369-72cjogxz 3966 6 NET net NN cord-015369-72cjogxz 3966 7 ) ) -RRB- cord-015369-72cjogxz 3966 8 of of IN cord-015369-72cjogxz 3966 9 the the DT cord-015369-72cjogxz 3966 10 gut gut NN cord-015369-72cjogxz 3966 11 such such PDT cord-015369-72cjogxz 3966 12 a a DT cord-015369-72cjogxz 3966 13 bad bad JJ cord-015369-72cjogxz 3966 14 prognosis prognosis NN cord-015369-72cjogxz 3966 15 ? ? . cord-015369-72cjogxz 3967 1 NETs net NNS cord-015369-72cjogxz 3967 2 in in IN cord-015369-72cjogxz 3967 3 the the DT cord-015369-72cjogxz 3967 4 gut gut NN cord-015369-72cjogxz 3967 5 mostly mostly RB cord-015369-72cjogxz 3967 6 present present JJ cord-015369-72cjogxz 3967 7 multifocal multifocal JJ cord-015369-72cjogxz 3967 8 disease disease NN cord-015369-72cjogxz 3967 9 with with IN cord-015369-72cjogxz 3967 10 predominance predominance NN cord-015369-72cjogxz 3967 11 of of IN cord-015369-72cjogxz 3967 12 terminal terminal JJ cord-015369-72cjogxz 3967 13 ileum ileum NN cord-015369-72cjogxz 3967 14 and and CC cord-015369-72cjogxz 3967 15 coecum coecum NN cord-015369-72cjogxz 3967 16 . . . cord-015369-72cjogxz 3968 1 Diameter diameter NN cord-015369-72cjogxz 3968 2 of of IN cord-015369-72cjogxz 3968 3 the the DT cord-015369-72cjogxz 3968 4 NET net NN cord-015369-72cjogxz 3968 5 mostly mostly RB cord-015369-72cjogxz 3968 6 is be VBZ cord-015369-72cjogxz 3968 7 above above IN cord-015369-72cjogxz 3968 8 2 2 CD cord-015369-72cjogxz 3968 9 centimetres centimetre NNS cord-015369-72cjogxz 3968 10 , , , cord-015369-72cjogxz 3968 11 and and CC cord-015369-72cjogxz 3968 12 tumor tumor NN cord-015369-72cjogxz 3968 13 tissue tissue NN cord-015369-72cjogxz 3968 14 already already RB cord-015369-72cjogxz 3968 15 infiltrates infiltrate VBZ cord-015369-72cjogxz 3968 16 muscularis muscularis NNP cord-015369-72cjogxz 3968 17 mucosae mucosae NNP cord-015369-72cjogxz 3968 18 , , , cord-015369-72cjogxz 3968 19 with with IN cord-015369-72cjogxz 3968 20 or or CC cord-015369-72cjogxz 3968 21 without without IN cord-015369-72cjogxz 3968 22 lymph lymph NN cord-015369-72cjogxz 3968 23 node node NN cord-015369-72cjogxz 3968 24 metastasis metastasis NN cord-015369-72cjogxz 3968 25 . . . cord-015369-72cjogxz 3969 1 Belonging belong VBG cord-015369-72cjogxz 3969 2 to to IN cord-015369-72cjogxz 3969 3 the the DT cord-015369-72cjogxz 3969 4 desmoplastic desmoplastic JJ cord-015369-72cjogxz 3969 5 reaction reaction NN cord-015369-72cjogxz 3969 6 , , , cord-015369-72cjogxz 3969 7 obstruction obstruction NN cord-015369-72cjogxz 3969 8 of of IN cord-015369-72cjogxz 3969 9 intestine intestine NN cord-015369-72cjogxz 3969 10 is be VBZ cord-015369-72cjogxz 3969 11 not not RB cord-015369-72cjogxz 3969 12 rather rather RB cord-015369-72cjogxz 3969 13 seen see VBN cord-015369-72cjogxz 3969 14 . . . cord-015369-72cjogxz 3970 1 30 30 CD cord-015369-72cjogxz 3970 2 - - SYM cord-015369-72cjogxz 3970 3 40 40 CD cord-015369-72cjogxz 3970 4 % % NN cord-015369-72cjogxz 3970 5 of of IN cord-015369-72cjogxz 3970 6 all all DT cord-015369-72cjogxz 3970 7 NET net NN cord-015369-72cjogxz 3970 8 's 's POS cord-015369-72cjogxz 3970 9 of of IN cord-015369-72cjogxz 3970 10 the the DT cord-015369-72cjogxz 3970 11 gut gut NN cord-015369-72cjogxz 3970 12 are be VBP cord-015369-72cjogxz 3970 13 diagnosed diagnose VBN cord-015369-72cjogxz 3970 14 by by IN cord-015369-72cjogxz 3970 15 doing do VBG cord-015369-72cjogxz 3970 16 surgery surgery NN cord-015369-72cjogxz 3970 17 because because IN cord-015369-72cjogxz 3970 18 of of IN cord-015369-72cjogxz 3970 19 an an DT cord-015369-72cjogxz 3970 20 ileus ileus NN cord-015369-72cjogxz 3970 21 . . . cord-015369-72cjogxz 3971 1 15 15 CD cord-015369-72cjogxz 3971 2 - - SYM cord-015369-72cjogxz 3971 3 20 20 CD cord-015369-72cjogxz 3971 4 % % NN cord-015369-72cjogxz 3971 5 have have VBP cord-015369-72cjogxz 3971 6 liver liver NN cord-015369-72cjogxz 3971 7 metastasis metastasis NN cord-015369-72cjogxz 3971 8 with with IN cord-015369-72cjogxz 3971 9 carcinoid carcinoid NN cord-015369-72cjogxz 3971 10 syndrome syndrome NN cord-015369-72cjogxz 3971 11 . . . cord-015369-72cjogxz 3972 1 In in IN cord-015369-72cjogxz 3972 2 a a DT cord-015369-72cjogxz 3972 3 period period NN cord-015369-72cjogxz 3972 4 from from IN cord-015369-72cjogxz 3972 5 1988 1988 CD cord-015369-72cjogxz 3972 6 till till IN cord-015369-72cjogxz 3972 7 2008 2008 CD cord-015369-72cjogxz 3972 8 we -PRON- PRP cord-015369-72cjogxz 3972 9 operated operate VBD cord-015369-72cjogxz 3972 10 20 20 CD cord-015369-72cjogxz 3972 11 patients patient NNS cord-015369-72cjogxz 3972 12 because because IN cord-015369-72cjogxz 3972 13 of of IN cord-015369-72cjogxz 3972 14 guts gut NNS cord-015369-72cjogxz 3972 15 NET net NN cord-015369-72cjogxz 3972 16 . . . cord-015369-72cjogxz 3973 1 Half half NN cord-015369-72cjogxz 3973 2 of of IN cord-015369-72cjogxz 3973 3 them -PRON- PRP cord-015369-72cjogxz 3973 4 were be VBD cord-015369-72cjogxz 3973 5 operated operate VBN cord-015369-72cjogxz 3973 6 electively electively RB cord-015369-72cjogxz 3973 7 within within IN cord-015369-72cjogxz 3973 8 a a DT cord-015369-72cjogxz 3973 9 few few JJ cord-015369-72cjogxz 3973 10 days day NNS cord-015369-72cjogxz 3973 11 ; ; : cord-015369-72cjogxz 3973 12 the the DT cord-015369-72cjogxz 3973 13 others other NNS cord-015369-72cjogxz 3973 14 had have VBD cord-015369-72cjogxz 3973 15 an an DT cord-015369-72cjogxz 3973 16 acute acute JJ cord-015369-72cjogxz 3973 17 operation operation NN cord-015369-72cjogxz 3973 18 within within IN cord-015369-72cjogxz 3973 19 a a DT cord-015369-72cjogxz 3973 20 few few JJ cord-015369-72cjogxz 3973 21 hours hour NNS cord-015369-72cjogxz 3973 22 in in IN cord-015369-72cjogxz 3973 23 case case NN cord-015369-72cjogxz 3973 24 of of IN cord-015369-72cjogxz 3973 25 ileus ileus NNP cord-015369-72cjogxz 3973 26 . . . cord-015369-72cjogxz 3974 1 Median median JJ cord-015369-72cjogxz 3974 2 age age NN cord-015369-72cjogxz 3974 3 was be VBD cord-015369-72cjogxz 3974 4 similar similar JJ cord-015369-72cjogxz 3974 5 with with IN cord-015369-72cjogxz 3974 6 about about RB cord-015369-72cjogxz 3974 7 68 68 CD cord-015369-72cjogxz 3974 8 years year NNS cord-015369-72cjogxz 3974 9 . . . cord-015369-72cjogxz 3975 1 All all DT cord-015369-72cjogxz 3975 2 operations operation NNS cord-015369-72cjogxz 3975 3 have have VBP cord-015369-72cjogxz 3975 4 been be VBN cord-015369-72cjogxz 3975 5 done do VBN cord-015369-72cjogxz 3975 6 by by IN cord-015369-72cjogxz 3975 7 specialists specialist NNS cord-015369-72cjogxz 3975 8 . . . cord-015369-72cjogxz 3976 1 In in IN cord-015369-72cjogxz 3976 2 none none NN cord-015369-72cjogxz 3976 3 of of IN cord-015369-72cjogxz 3976 4 the the DT cord-015369-72cjogxz 3976 5 cases case NNS cord-015369-72cjogxz 3976 6 diagnose diagnose VB cord-015369-72cjogxz 3976 7 was be VBD cord-015369-72cjogxz 3976 8 felt feel VBN cord-015369-72cjogxz 3976 9 preoperatively preoperatively JJ cord-015369-72cjogxz 3976 10 . . . cord-015369-72cjogxz 3977 1 Histological histological JJ cord-015369-72cjogxz 3977 2 results result NNS cord-015369-72cjogxz 3977 3 of of IN cord-015369-72cjogxz 3977 4 planned plan VBN cord-015369-72cjogxz 3977 5 operations operation NNS cord-015369-72cjogxz 3977 6 all all DT cord-015369-72cjogxz 3977 7 showed show VBD cord-015369-72cjogxz 3977 8 well well RB cord-015369-72cjogxz 3977 9 differentiated differentiated JJ cord-015369-72cjogxz 3977 10 carcinomas carcinoma NNS cord-015369-72cjogxz 3977 11 with with IN cord-015369-72cjogxz 3977 12 rate rate NN cord-015369-72cjogxz 3977 13 of of IN cord-015369-72cjogxz 3977 14 distant distant JJ cord-015369-72cjogxz 3977 15 metastasis metastasis NN cord-015369-72cjogxz 3977 16 of of IN cord-015369-72cjogxz 3977 17 50 50 CD cord-015369-72cjogxz 3977 18 % % NN cord-015369-72cjogxz 3977 19 , , , cord-015369-72cjogxz 3977 20 lymph lymph NN cord-015369-72cjogxz 3977 21 node node NN cord-015369-72cjogxz 3977 22 metastasis metastasis NN cord-015369-72cjogxz 3977 23 of of IN cord-015369-72cjogxz 3977 24 70 70 CD cord-015369-72cjogxz 3977 25 % % NN cord-015369-72cjogxz 3977 26 , , , cord-015369-72cjogxz 3977 27 contrary contrary JJ cord-015369-72cjogxz 3977 28 to to IN cord-015369-72cjogxz 3977 29 acute acute JJ cord-015369-72cjogxz 3977 30 operations operation NNS cord-015369-72cjogxz 3977 31 , , , cord-015369-72cjogxz 3977 32 which which WDT cord-015369-72cjogxz 3977 33 showed show VBD cord-015369-72cjogxz 3977 34 bad bad JJ cord-015369-72cjogxz 3977 35 differentiated differentiated JJ cord-015369-72cjogxz 3977 36 carcinomas carcinoma NNS cord-015369-72cjogxz 3977 37 in in IN cord-015369-72cjogxz 3977 38 50 50 CD cord-015369-72cjogxz 3977 39 % % NN cord-015369-72cjogxz 3977 40 with with IN cord-015369-72cjogxz 3977 41 rate rate NN cord-015369-72cjogxz 3977 42 of of IN cord-015369-72cjogxz 3977 43 distant distant JJ cord-015369-72cjogxz 3977 44 metastasis metastasis NN cord-015369-72cjogxz 3977 45 and and CC cord-015369-72cjogxz 3977 46 lymph lymph NN cord-015369-72cjogxz 3977 47 node node NN cord-015369-72cjogxz 3977 48 metastasis metastasis NN cord-015369-72cjogxz 3977 49 of of IN cord-015369-72cjogxz 3977 50 80 80 CD cord-015369-72cjogxz 3977 51 % % NN cord-015369-72cjogxz 3977 52 . . . cord-015369-72cjogxz 3978 1 According accord VBG cord-015369-72cjogxz 3978 2 to to IN cord-015369-72cjogxz 3978 3 the the DT cord-015369-72cjogxz 3978 4 ENET ENET NNP cord-015369-72cjogxz 3978 5 2006 2006 CD cord-015369-72cjogxz 3978 6 classification classification NN cord-015369-72cjogxz 3978 7 mean mean VBP cord-015369-72cjogxz 3978 8 part part NN cord-015369-72cjogxz 3978 9 of of IN cord-015369-72cjogxz 3978 10 tumors tumor NNS cord-015369-72cjogxz 3978 11 belonged belong VBN cord-015369-72cjogxz 3978 12 to to IN cord-015369-72cjogxz 3978 13 stage stage NN cord-015369-72cjogxz 3978 14 IIIb IIIb NNP cord-015369-72cjogxz 3978 15 and and CC cord-015369-72cjogxz 3978 16 IV IV NNP cord-015369-72cjogxz 3978 17 . . . cord-015369-72cjogxz 3979 1 Median median JJ cord-015369-72cjogxz 3979 2 survival survival NN cord-015369-72cjogxz 3979 3 in in IN cord-015369-72cjogxz 3979 4 the the DT cord-015369-72cjogxz 3979 5 first first JJ cord-015369-72cjogxz 3979 6 group group NN cord-015369-72cjogxz 3979 7 was be VBD cord-015369-72cjogxz 3979 8 59.5 59.5 CD cord-015369-72cjogxz 3979 9 AE AE NNP cord-015369-72cjogxz 3979 10 15.88 15.88 CD cord-015369-72cjogxz 3979 11 , , , cord-015369-72cjogxz 3979 12 in in IN cord-015369-72cjogxz 3979 13 the the DT cord-015369-72cjogxz 3979 14 acute acute JJ cord-015369-72cjogxz 3979 15 group group NN cord-015369-72cjogxz 3979 16 30 30 CD cord-015369-72cjogxz 3979 17 AE AE NNP cord-015369-72cjogxz 3979 18 34.67 34.67 CD cord-015369-72cjogxz 3979 19 months month NNS cord-015369-72cjogxz 3979 20 . . . cord-015369-72cjogxz 3980 1 Because because IN cord-015369-72cjogxz 3980 2 of of IN cord-015369-72cjogxz 3980 3 an an DT cord-015369-72cjogxz 3980 4 a a FW cord-015369-72cjogxz 3980 5 priori priori RB cord-015369-72cjogxz 3980 6 more more RBR cord-015369-72cjogxz 3980 7 radical radical JJ cord-015369-72cjogxz 3980 8 surgery surgery NN cord-015369-72cjogxz 3980 9 in in IN cord-015369-72cjogxz 3980 10 planned plan VBN cord-015369-72cjogxz 3980 11 operations operation NNS cord-015369-72cjogxz 3980 12 , , , cord-015369-72cjogxz 3980 13 survival survival NN cord-015369-72cjogxz 3980 14 is be VBZ cord-015369-72cjogxz 3980 15 considerably considerably RB cord-015369-72cjogxz 3980 16 better well JJR cord-015369-72cjogxz 3980 17 . . . cord-015369-72cjogxz 3981 1 Perhaps perhaps RB cord-015369-72cjogxz 3981 2 this this DT cord-015369-72cjogxz 3981 3 point point NN cord-015369-72cjogxz 3981 4 might may MD cord-015369-72cjogxz 3981 5 be be VB cord-015369-72cjogxz 3981 6 the the DT cord-015369-72cjogxz 3981 7 solution solution NN cord-015369-72cjogxz 3981 8 in in IN cord-015369-72cjogxz 3981 9 order order NN cord-015369-72cjogxz 3981 10 to to TO cord-015369-72cjogxz 3981 11 improve improve VB cord-015369-72cjogxz 3981 12 prognosis prognosis NN cord-015369-72cjogxz 3981 13 of of IN cord-015369-72cjogxz 3981 14 guts gut NNS cord-015369-72cjogxz 3981 15 NET net NN cord-015369-72cjogxz 3981 16 . . . cord-015369-72cjogxz 3982 1 Gastrointestinale Gastrointestinale NNP cord-015369-72cjogxz 3982 2 Frühkarzinome Frühkarzinome NNP cord-015369-72cjogxz 3982 3 des des FW cord-015369-72cjogxz 3982 4 oberen oberen NNP cord-015369-72cjogxz 3982 5 GI GI NNP cord-015369-72cjogxz 3982 6 - - HYPH cord-015369-72cjogxz 3982 7 Trakts Trakts NNP cord-015369-72cjogxz 3982 8 : : : cord-015369-72cjogxz 3983 1 Eine Eine NNP cord-015369-72cjogxz 3983 2 viszeralmedizinische viszeralmedizinische NN cord-015369-72cjogxz 3983 3 Herausforderung Herausforderung NNP cord-015369-72cjogxz 3983 4 Innere Innere NNP cord-015369-72cjogxz 3983 5 Medizin Medizin NNP cord-015369-72cjogxz 3983 6 2 2 CD cord-015369-72cjogxz 3983 7 , , , cord-015369-72cjogxz 3983 8 HSK HSK NNP cord-015369-72cjogxz 3983 9 - - HYPH cord-015369-72cjogxz 3983 10 Kliniken Kliniken NNP cord-015369-72cjogxz 3983 11 , , , cord-015369-72cjogxz 3983 12 Wiesbaden Wiesbaden NNP cord-015369-72cjogxz 3984 1 , , , cord-015369-72cjogxz 3984 2 Germany Germany NNP cord-015369-72cjogxz 3984 3 Die Die NNP cord-015369-72cjogxz 3984 4 endoskopische endoskopische NNP cord-015369-72cjogxz 3984 5 Therapie Therapie NNP cord-015369-72cjogxz 3984 6 von von NNP cord-015369-72cjogxz 3984 7 prämalignen prämalignen NNP cord-015369-72cjogxz 3985 1 und und NNP cord-015369-72cjogxz 3985 2 malignen malignen NNP cord-015369-72cjogxz 3986 1 Läsionen Läsionen NNP cord-015369-72cjogxz 3986 2 i -PRON- PRP cord-015369-72cjogxz 3986 3 m be VBP cord-015369-72cjogxz 3986 4 oberen oberen NNP cord-015369-72cjogxz 3987 1 Gastrointestinaltrakt Gastrointestinaltrakt NNS cord-015369-72cjogxz 3987 2 hat hat NN cord-015369-72cjogxz 3987 3 in in IN cord-015369-72cjogxz 3987 4 den den NNP cord-015369-72cjogxz 3987 5 letzten letzten NNP cord-015369-72cjogxz 3987 6 Jahren Jahren NNP cord-015369-72cjogxz 3987 7 zunehmend zunehmend NNP cord-015369-72cjogxz 3987 8 an an DT cord-015369-72cjogxz 3987 9 Bedeutung Bedeutung NNP cord-015369-72cjogxz 3987 10 gewonnen gewonnen NNP cord-015369-72cjogxz 3987 11 . . . cord-015369-72cjogxz 3988 1 Dabei Dabei NNP cord-015369-72cjogxz 3988 2 war war NN cord-015369-72cjogxz 3988 3 und und XX cord-015369-72cjogxz 3989 1 ist ist NNP cord-015369-72cjogxz 3989 2 die die VBP cord-015369-72cjogxz 3990 1 technische technische NNP cord-015369-72cjogxz 3990 2 Weiterentwicklung Weiterentwicklung NNP cord-015369-72cjogxz 3991 1 i -PRON- PRP cord-015369-72cjogxz 3991 2 m be VBP cord-015369-72cjogxz 3991 3 Bereich Bereich NNP cord-015369-72cjogxz 3991 4 der der NNP cord-015369-72cjogxz 3991 5 Diagnostik Diagnostik NNP cord-015369-72cjogxz 3992 1 ( ( -LRB- cord-015369-72cjogxz 3992 2 Einsatz Einsatz NNP cord-015369-72cjogxz 3992 3 einer einer NN cord-015369-72cjogxz 3992 4 hochauflösenden hochauflösenden JJ cord-015369-72cjogxz 3993 1 Videoendoskopie Videoendoskopie NNP cord-015369-72cjogxz 3993 2 unter unter NNP cord-015369-72cjogxz 3993 3 Einbeziehung Einbeziehung NNP cord-015369-72cjogxz 3994 1 einer einer NNP cord-015369-72cjogxz 3994 2 virtuellen virtuellen NNP cord-015369-72cjogxz 3994 3 oder oder NNP cord-015369-72cjogxz 3994 4 realen realen NNP cord-015369-72cjogxz 3994 5 Chromoendoskopie Chromoendoskopie NNP cord-015369-72cjogxz 3994 6 ) ) -RRB- cord-015369-72cjogxz 3994 7 die die VBP cord-015369-72cjogxz 3994 8 integrale integrale NN cord-015369-72cjogxz 3994 9 Voraussetzung Voraussetzung NNP cord-015369-72cjogxz 3994 10 , , , cord-015369-72cjogxz 3994 11 um um UH cord-015369-72cjogxz 3994 12 eine eine NNP cord-015369-72cjogxz 3994 13 Detektion Detektion NNP cord-015369-72cjogxz 3994 14 von von NNP cord-015369-72cjogxz 3994 15 frü frü NN cord-015369-72cjogxz 3994 16 hen hen NN cord-015369-72cjogxz 3994 17 neoplastischen neoplastischen NNP cord-015369-72cjogxz 3994 18 Veränderungen Veränderungen NNP cord-015369-72cjogxz 3994 19 zu zu NNP cord-015369-72cjogxz 3994 20 ermöglichen ermöglichen NNP cord-015369-72cjogxz 3994 21 . . . cord-015369-72cjogxz 3995 1 Ebenso Ebenso NNP cord-015369-72cjogxz 3995 2 stehen stehen NNP cord-015369-72cjogxz 3995 3 dem dem NNP cord-015369-72cjogxz 3995 4 Endoskopiker Endoskopiker NNP cord-015369-72cjogxz 3995 5 therapeutisch therapeutisch VBD cord-015369-72cjogxz 3995 6 diverse diverse JJ cord-015369-72cjogxz 3995 7 neue neue NNP cord-015369-72cjogxz 3995 8 Verfahren Verfahren NNP cord-015369-72cjogxz 3995 9 zur zur NNP cord-015369-72cjogxz 3995 10 Verfügung Verfügung NNP cord-015369-72cjogxz 3995 11 ( ( -LRB- cord-015369-72cjogxz 3995 12 Resektionsmesser Resektionsmesser NNP cord-015369-72cjogxz 3995 13 , , , cord-015369-72cjogxz 3995 14 neue neue NNP cord-015369-72cjogxz 3995 15 Ablationstechniken Ablationstechniken NNP cord-015369-72cjogxz 3995 16 z. z. NNP cord-015369-72cjogxz 3996 1 B. B. NNP cord-015369-72cjogxz 3996 2 Halo Halo NNP cord-015369-72cjogxz 3996 3 - - HYPH cord-015369-72cjogxz 3996 4 Ablation Ablation NNP cord-015369-72cjogxz 3996 5 ) ) -RRB- cord-015369-72cjogxz 3996 6 , , , cord-015369-72cjogxz 3996 7 die die VBP cord-015369-72cjogxz 3996 8 eine eine NNP cord-015369-72cjogxz 3996 9 invasive invasive JJ cord-015369-72cjogxz 3996 10 und und IN cord-015369-72cjogxz 3996 11 sichere sichere NNP cord-015369-72cjogxz 3996 12 endoskopische endoskopische NNP cord-015369-72cjogxz 3996 13 Therapie Therapie NNP cord-015369-72cjogxz 3996 14 ermöglichen ermöglichen NN cord-015369-72cjogxz 3996 15 . . . cord-015369-72cjogxz 3997 1 In in IN cord-015369-72cjogxz 3997 2 einem einem NNP cord-015369-72cjogxz 3997 3 kürzlich kürzlich NNP cord-015369-72cjogxz 3997 4 von von NNP cord-015369-72cjogxz 3997 5 unserer unserer JJ cord-015369-72cjogxz 3997 6 Arbeitsgruppe Arbeitsgruppe NNP cord-015369-72cjogxz 3997 7 veröffentlichten veröffentlichten VBD cord-015369-72cjogxz 3997 8 5-Jahres 5-Jahres NNP cord-015369-72cjogxz 3997 9 - - HYPH cord-015369-72cjogxz 3997 10 Follow follow NN cord-015369-72cjogxz 3997 11 - - HYPH cord-015369-72cjogxz 3997 12 up up NN cord-015369-72cjogxz 3997 13 von von NNP cord-015369-72cjogxz 3997 14 349 349 CD cord-015369-72cjogxz 3997 15 Patienten Patienten NNP cord-015369-72cjogxz 3997 16 mit mit NNP cord-015369-72cjogxz 3997 17 einer einer NNP cord-015369-72cjogxz 3997 18 hochgradigen hochgradigen NNP cord-015369-72cjogxz 3998 1 Neoplasie Neoplasie NNP cord-015369-72cjogxz 3999 1 i -PRON- PRP cord-015369-72cjogxz 3999 2 m be VBP cord-015369-72cjogxz 3999 3 Barrettösophagus Barrettösophagus NNP cord-015369-72cjogxz 3999 4 bzw bzw NNP cord-015369-72cjogxz 3999 5 . . . cord-015369-72cjogxz 4000 1 einem einem NNP cord-015369-72cjogxz 4000 2 Barrettfrühkarzinom Barrettfrühkarzinom NNP cord-015369-72cjogxz 4000 3 konnten konnten NNP cord-015369-72cjogxz 4000 4 wir wir NNP cord-015369-72cjogxz 4001 1 eine eine NNP cord-015369-72cjogxz 4001 2 erfolgreiche erfolgreiche NNP cord-015369-72cjogxz 4001 3 Therapie Therapie NNP cord-015369-72cjogxz 4001 4 in in IN cord-015369-72cjogxz 4001 5 über über NNP cord-015369-72cjogxz 4001 6 96 96 CD cord-015369-72cjogxz 4001 7 % % NN cord-015369-72cjogxz 4001 8 der der NNP cord-015369-72cjogxz 4001 9 Patienten Patienten NNP cord-015369-72cjogxz 4001 10 dokumentieren dokumentieren NNP cord-015369-72cjogxz 4001 11 . . . cord-015369-72cjogxz 4002 1 Bezüglich Bezüglich NNP cord-015369-72cjogxz 4002 2 des des FW cord-015369-72cjogxz 4002 3 Plattenepithelfrühkarzinoms Plattenepithelfrühkarzinoms NNP cord-015369-72cjogxz 4002 4 des des FW cord-015369-72cjogxz 4002 5 Ö Ö NNP cord-015369-72cjogxz 4002 6 sophagus sophagus FW cord-015369-72cjogxz 4002 7 wurden wurden NNS cord-015369-72cjogxz 4003 1 2007 2007 CD cord-015369-72cjogxz 4003 2 aus aus NNP cord-015369-72cjogxz 4003 3 3 3 CD cord-015369-72cjogxz 4003 4 Arbeitsgruppen Arbeitsgruppen NNP cord-015369-72cjogxz 4003 5 5-Jahres 5-Jahres NNP cord-015369-72cjogxz 4003 6 - - HYPH cord-015369-72cjogxz 4003 7 Ü Ü NNP cord-015369-72cjogxz 4003 8 berlebensdaten berlebensdaten NNP cord-015369-72cjogxz 4003 9 publiziert publiziert NNP cord-015369-72cjogxz 4004 1 ; ; : cord-015369-72cjogxz 4004 2 hier hier NNP cord-015369-72cjogxz 4004 3 zeigte zeigte NNP cord-015369-72cjogxz 4004 4 sich sich NNP cord-015369-72cjogxz 4005 1 ein ein NNP cord-015369-72cjogxz 4005 2 5-Jahresüberleben 5-Jahresüberleben NNP cord-015369-72cjogxz 4005 3 von von NNP cord-015369-72cjogxz 4006 1 58 58 CD cord-015369-72cjogxz 4006 2 % % NN cord-015369-72cjogxz 4006 3 in in IN cord-015369-72cjogxz 4006 4 der der NNP cord-015369-72cjogxz 4006 5 Lyoner Lyoner NNP cord-015369-72cjogxz 4006 6 Gruppe Gruppe NNP cord-015369-72cjogxz 4006 7 vs. vs. IN cord-015369-72cjogxz 4006 8 77 77 CD cord-015369-72cjogxz 4006 9 % % NN cord-015369-72cjogxz 4006 10 der der NN cord-015369-72cjogxz 4006 11 Wiesbadener Wiesbadener NNP cord-015369-72cjogxz 4006 12 Patienten Patienten NNP cord-015369-72cjogxz 4006 13 vs. vs. IN cord-015369-72cjogxz 4006 14 79 79 CD cord-015369-72cjogxz 4006 15 % % NN cord-015369-72cjogxz 4006 16 in in IN cord-015369-72cjogxz 4006 17 einem einem NNP cord-015369-72cjogxz 4006 18 japanischen japanischen NNP cord-015369-72cjogxz 4006 19 Kollektiv Kollektiv NNP cord-015369-72cjogxz 4006 20 . . . cord-015369-72cjogxz 4007 1 Eine Eine NNP cord-015369-72cjogxz 4007 2 weitere weitere NNP cord-015369-72cjogxz 4007 3 Arbeit Arbeit NNP cord-015369-72cjogxz 4007 4 aus aus NNP cord-015369-72cjogxz 4007 5 Japan Japan NNP cord-015369-72cjogxz 4007 6 , , , cord-015369-72cjogxz 4007 7 in in IN cord-015369-72cjogxz 4007 8 der der NNP cord-015369-72cjogxz 4007 9 das das NNP cord-015369-72cjogxz 4007 10 technische technische NNP cord-015369-72cjogxz 4007 11 Vorgehen Vorgehen NNP cord-015369-72cjogxz 4007 12 der der NNP cord-015369-72cjogxz 4007 13 endoskopische endoskopische NNP cord-015369-72cjogxz 4007 14 Therapie Therapie NNP cord-015369-72cjogxz 4007 15 ( ( -LRB- cord-015369-72cjogxz 4007 16 ESD ESD NNP cord-015369-72cjogxz 4007 17 vs. vs. FW cord-015369-72cjogxz 4007 18 ER ER NNP cord-015369-72cjogxz 4007 19 ) ) -RRB- cord-015369-72cjogxz 4008 1 evaluiert evaluiert NNP cord-015369-72cjogxz 4008 2 wurde wurde NNP cord-015369-72cjogxz 4008 3 , , , cord-015369-72cjogxz 4008 4 konnte konnte NNP cord-015369-72cjogxz 4008 5 in in IN cord-015369-72cjogxz 4008 6 99 99 CD cord-015369-72cjogxz 4008 7 % % NN cord-015369-72cjogxz 4009 1 der der NNP cord-015369-72cjogxz 4009 2 Patienten Patienten NNP cord-015369-72cjogxz 4009 3 ein ein NNP cord-015369-72cjogxz 4009 4 3-Jahres 3-jahres CD cord-015369-72cjogxz 4009 5 - - HYPH cord-015369-72cjogxz 4009 6 Ü Ü NNP cord-015369-72cjogxz 4009 7 berleben berleben NN cord-015369-72cjogxz 4009 8 dokumentieren dokumentieren NNP cord-015369-72cjogxz 4009 9 . . . cord-015369-72cjogxz 4010 1 Die die VB cord-015369-72cjogxz 4010 2 in in IN cord-015369-72cjogxz 4010 3 den den NNP cord-015369-72cjogxz 4010 4 letzten letzten NNP cord-015369-72cjogxz 4010 5 3 3 CD cord-015369-72cjogxz 4010 6 Jahren Jahren NNP cord-015369-72cjogxz 4011 1 publizierten publizierten NNP cord-015369-72cjogxz 4011 2 Langzeitdaten Langzeitdaten NNP cord-015369-72cjogxz 4011 3 von von NNP cord-015369-72cjogxz 4011 4 Patienten Patienten NNP cord-015369-72cjogxz 4012 1 mit mit NNP cord-015369-72cjogxz 4012 2 T1-Tumoren T1-Tumoren NNP cord-015369-72cjogxz 4012 3 der der NNP cord-015369-72cjogxz 4012 4 Speiseröhre Speiseröhre NNP cord-015369-72cjogxz 4013 1 und und NNP cord-015369-72cjogxz 4014 1 des des NNP cord-015369-72cjogxz 4014 2 Magens Magens NNP cord-015369-72cjogxz 4014 3 beweisen beweisen NNP cord-015369-72cjogxz 4014 4 , , , cord-015369-72cjogxz 4014 5 dass dass NNP cord-015369-72cjogxz 4014 6 eine eine NNP cord-015369-72cjogxz 4014 7 endoskopische endoskopische NNP cord-015369-72cjogxz 4014 8 Therapie Therapie NNP cord-015369-72cjogxz 4014 9 in in IN cord-015369-72cjogxz 4014 10 kurativer kurativer NNP cord-015369-72cjogxz 4014 11 Intention intention NN cord-015369-72cjogxz 4014 12 bei bei NNP cord-015369-72cjogxz 4014 13 Einhaltung Einhaltung NNP cord-015369-72cjogxz 4014 14 definierter definierter NN cord-015369-72cjogxz 4014 15 histologischer histologischer JJ cord-015369-72cjogxz 4014 16 Kriterien Kriterien NNP cord-015369-72cjogxz 4014 17 die die VBP cord-015369-72cjogxz 4014 18 Therapie Therapie NNP cord-015369-72cjogxz 4014 19 der der NNP cord-015369-72cjogxz 4014 20 Wahl Wahl NNP cord-015369-72cjogxz 4014 21 ist ist NN cord-015369-72cjogxz 4014 22 . . . cord-015369-72cjogxz 4015 1 Zusätzlich Zusätzlich NNP cord-015369-72cjogxz 4015 2 können können UH cord-015369-72cjogxz 4015 3 die die VBP cord-015369-72cjogxz 4015 4 Arbeiten Arbeiten NNP cord-015369-72cjogxz 4015 5 belegen belegen NNP cord-015369-72cjogxz 4015 6 , , , cord-015369-72cjogxz 4015 7 dass dass NNP cord-015369-72cjogxz 4015 8 es es NNP cord-015369-72cjogxz 4015 9 sich sich NNP cord-015369-72cjogxz 4015 10 hierbei hierbei NNP cord-015369-72cjogxz 4015 11 um um UH cord-015369-72cjogxz 4015 12 ein ein NNP cord-015369-72cjogxz 4015 13 sicheres sichere NNS cord-015369-72cjogxz 4015 14 und und IN cord-015369-72cjogxz 4015 15 komplikationsarmes komplikationsarmes NNP cord-015369-72cjogxz 4015 16 Therapieverfahren Therapieverfahren NNP cord-015369-72cjogxz 4015 17 handelt handelt NNP cord-015369-72cjogxz 4015 18 , , , cord-015369-72cjogxz 4015 19 dass dass NNP cord-015369-72cjogxz 4015 20 entsprechend entsprechend NNP cord-015369-72cjogxz 4015 21 mit mit NNP cord-015369-72cjogxz 4015 22 einer einer NNP cord-015369-72cjogxz 4015 23 niedrigen niedrigen NNP cord-015369-72cjogxz 4015 24 Morbidität Morbidität NNP cord-015369-72cjogxz 4015 25 und und XX cord-015369-72cjogxz 4016 1 Mortalität Mortalität NNP cord-015369-72cjogxz 4016 2 verknüpft verknüpft NNS cord-015369-72cjogxz 4016 3 ist ist NNP cord-015369-72cjogxz 4016 4 . . . cord-015369-72cjogxz 4016 5 _SP cord-015369-72cjogxz 4017 1 While while IN cord-015369-72cjogxz 4017 2 the the DT cord-015369-72cjogxz 4017 3 use use NN cord-015369-72cjogxz 4017 4 of of IN cord-015369-72cjogxz 4017 5 breast breast NN cord-015369-72cjogxz 4017 6 conserving conserve VBG cord-015369-72cjogxz 4017 7 surgery surgery NN cord-015369-72cjogxz 4017 8 increased increase VBD cord-015369-72cjogxz 4017 9 during during IN cord-015369-72cjogxz 4017 10 the the DT cord-015369-72cjogxz 4017 11 last last JJ cord-015369-72cjogxz 4017 12 century century NN cord-015369-72cjogxz 4017 13 due due IN cord-015369-72cjogxz 4017 14 to to IN cord-015369-72cjogxz 4017 15 strong strong JJ cord-015369-72cjogxz 4017 16 scientific scientific JJ cord-015369-72cjogxz 4017 17 data datum NNS cord-015369-72cjogxz 4017 18 regarding regard VBG cord-015369-72cjogxz 4017 19 oncologic oncologic JJ cord-015369-72cjogxz 4017 20 safety safety NN cord-015369-72cjogxz 4017 21 , , , cord-015369-72cjogxz 4017 22 only only RB cord-015369-72cjogxz 4017 23 little little JJ cord-015369-72cjogxz 4017 24 has have VBZ cord-015369-72cjogxz 4017 25 been be VBN cord-015369-72cjogxz 4017 26 done do VBN cord-015369-72cjogxz 4017 27 to to TO cord-015369-72cjogxz 4017 28 improve improve VB cord-015369-72cjogxz 4017 29 the the DT cord-015369-72cjogxz 4017 30 real real JJ cord-015369-72cjogxz 4017 31 goal goal NN cord-015369-72cjogxz 4017 32 of of IN cord-015369-72cjogxz 4017 33 breast breast NN cord-015369-72cjogxz 4017 34 conservation conservation NN cord-015369-72cjogxz 4018 1 , , , cord-015369-72cjogxz 4018 2 cosmetic cosmetic JJ cord-015369-72cjogxz 4018 3 outcome outcome NN cord-015369-72cjogxz 4018 4 . . . cord-015369-72cjogxz 4019 1 Oncoplastic oncoplastic JJ cord-015369-72cjogxz 4019 2 surgery surgery NN cord-015369-72cjogxz 4019 3 is be VBZ cord-015369-72cjogxz 4019 4 the the DT cord-015369-72cjogxz 4019 5 next next JJ cord-015369-72cjogxz 4019 6 important important JJ cord-015369-72cjogxz 4019 7 development development NN cord-015369-72cjogxz 4019 8 to to TO cord-015369-72cjogxz 4019 9 fulfill fulfill VB cord-015369-72cjogxz 4019 10 the the DT cord-015369-72cjogxz 4019 11 goal goal NN cord-015369-72cjogxz 4019 12 of of IN cord-015369-72cjogxz 4019 13 breast breast NN cord-015369-72cjogxz 4019 14 conservation conservation NN cord-015369-72cjogxz 4019 15 . . . cord-015369-72cjogxz 4020 1 However however RB cord-015369-72cjogxz 4020 2 , , , cord-015369-72cjogxz 4020 3 only only RB cord-015369-72cjogxz 4020 4 few few JJ cord-015369-72cjogxz 4020 5 scientific scientific JJ cord-015369-72cjogxz 4020 6 outstanding outstanding JJ cord-015369-72cjogxz 4020 7 original original JJ cord-015369-72cjogxz 4020 8 manuscripts manuscript NNS cord-015369-72cjogxz 4020 9 are be VBP cord-015369-72cjogxz 4020 10 available available JJ cord-015369-72cjogxz 4020 11 . . . cord-015369-72cjogxz 4021 1 This this DT cord-015369-72cjogxz 4021 2 talk talk NN cord-015369-72cjogxz 4021 3 gives give VBZ cord-015369-72cjogxz 4021 4 you -PRON- PRP cord-015369-72cjogxz 4021 5 an an DT cord-015369-72cjogxz 4021 6 overview overview NN cord-015369-72cjogxz 4021 7 about about IN cord-015369-72cjogxz 4021 8 scientific scientific JJ cord-015369-72cjogxz 4021 9 data datum NNS cord-015369-72cjogxz 4021 10 , , , cord-015369-72cjogxz 4021 11 future future JJ cord-015369-72cjogxz 4021 12 perspectives perspective NNS cord-015369-72cjogxz 4021 13 and and CC cord-015369-72cjogxz 4021 14 possible possible JJ cord-015369-72cjogxz 4021 15 borders border NNS cord-015369-72cjogxz 4021 16 . . . cord-015369-72cjogxz 4022 1 Cariatide Cariatide NNP cord-015369-72cjogxz 4022 2 study study NN cord-015369-72cjogxz 4022 3 : : : cord-015369-72cjogxz 4022 4 evaluation evaluation NN cord-015369-72cjogxz 4022 5 of of IN cord-015369-72cjogxz 4022 6 the the DT cord-015369-72cjogxz 4022 7 effect effect NN cord-015369-72cjogxz 4022 8 of of IN cord-015369-72cjogxz 4022 9 an an DT cord-015369-72cjogxz 4022 10 educational educational JJ cord-015369-72cjogxz 4022 11 approach approach NN cord-015369-72cjogxz 4022 12 on on IN cord-015369-72cjogxz 4022 13 compliance compliance NN cord-015369-72cjogxz 4022 14 and and CC cord-015369-72cjogxz 4022 15 adherence adherence NN cord-015369-72cjogxz 4022 16 to to IN cord-015369-72cjogxz 4022 17 adjuvant adjuvant JJ cord-015369-72cjogxz 4022 18 aromatase aromatase JJ cord-015369-72cjogxz 4022 19 inhibitor inhibitor NN cord-015369-72cjogxz 4022 20 therapy therapy NN cord-015369-72cjogxz 4022 21 for for IN cord-015369-72cjogxz 4022 22 postmenopausal postmenopausal JJ cord-015369-72cjogxz 4022 23 women woman NNS cord-015369-72cjogxz 4022 24 with with IN cord-015369-72cjogxz 4022 25 hormone hormone NN cord-015369-72cjogxz 4022 26 sensitive sensitive JJ cord-015369-72cjogxz 4022 27 breast breast NN cord-015369-72cjogxz 4022 28 cancer cancer NN cord-015369-72cjogxz 4023 1 The the DT cord-015369-72cjogxz 4023 2 efficacy efficacy NN cord-015369-72cjogxz 4023 3 of of IN cord-015369-72cjogxz 4023 4 AI AI NNP cord-015369-72cjogxz 4023 5 on on IN cord-015369-72cjogxz 4023 6 reducing reduce VBG cord-015369-72cjogxz 4023 7 breast breast NN cord-015369-72cjogxz 4023 8 cancer cancer NN cord-015369-72cjogxz 4023 9 recurrence recurrence NN cord-015369-72cjogxz 4023 10 , , , cord-015369-72cjogxz 4023 11 but but CC cord-015369-72cjogxz 4023 12 also also RB cord-015369-72cjogxz 4023 13 aspects aspect NNS cord-015369-72cjogxz 4023 14 of of IN cord-015369-72cjogxz 4023 15 health health NN cord-015369-72cjogxz 4023 16 economy economy NN cord-015369-72cjogxz 4023 17 , , , cord-015369-72cjogxz 4023 18 is be VBZ cord-015369-72cjogxz 4023 19 bound bind VBN cord-015369-72cjogxz 4023 20 to to IN cord-015369-72cjogxz 4023 21 the the DT cord-015369-72cjogxz 4023 22 adherence adherence NN cord-015369-72cjogxz 4023 23 of of IN cord-015369-72cjogxz 4023 24 regular regular JJ cord-015369-72cjogxz 4023 25 and and CC cord-015369-72cjogxz 4023 26 long long JJ cord-015369-72cjogxz 4023 27 - - HYPH cord-015369-72cjogxz 4023 28 term term NN cord-015369-72cjogxz 4023 29 intake intake NN cord-015369-72cjogxz 4023 30 of of IN cord-015369-72cjogxz 4023 31 the the DT cord-015369-72cjogxz 4023 32 medication medication NN cord-015369-72cjogxz 4023 33 . . . cord-015369-72cjogxz 4024 1 Aim aim VB cord-015369-72cjogxz 4024 2 . . . cord-015369-72cjogxz 4025 1 The the DT cord-015369-72cjogxz 4025 2 Cariatide Cariatide NNP cord-015369-72cjogxz 4025 3 Study Study NNP cord-015369-72cjogxz 4025 4 evaluates evaluate VBZ cord-015369-72cjogxz 4025 5 the the DT cord-015369-72cjogxz 4025 6 influence influence NN cord-015369-72cjogxz 4025 7 of of IN cord-015369-72cjogxz 4025 8 supporting support VBG cord-015369-72cjogxz 4025 9 educational educational JJ cord-015369-72cjogxz 4025 10 material material NN cord-015369-72cjogxz 4025 11 on on IN cord-015369-72cjogxz 4025 12 compliance compliance NN cord-015369-72cjogxz 4025 13 and and CC cord-015369-72cjogxz 4025 14 retention retention NN cord-015369-72cjogxz 4025 15 time time NN cord-015369-72cjogxz 4025 16 under under IN cord-015369-72cjogxz 4025 17 AI AI NNP cord-015369-72cjogxz 4025 18 therapy therapy NN cord-015369-72cjogxz 4025 19 in in IN cord-015369-72cjogxz 4025 20 hormone hormone NN cord-015369-72cjogxz 4025 21 receptor receptor NN cord-015369-72cjogxz 4025 22 positive positive JJ cord-015369-72cjogxz 4025 23 breast breast NN cord-015369-72cjogxz 4025 24 cancer cancer NN cord-015369-72cjogxz 4025 25 patients patient NNS cord-015369-72cjogxz 4025 26 . . . cord-015369-72cjogxz 4026 1 Furthermore furthermore RB cord-015369-72cjogxz 4026 2 , , , cord-015369-72cjogxz 4026 3 the the DT cord-015369-72cjogxz 4026 4 study study NN cord-015369-72cjogxz 4026 5 will will MD cord-015369-72cjogxz 4026 6 try try VB cord-015369-72cjogxz 4026 7 to to TO cord-015369-72cjogxz 4026 8 explore explore VB cord-015369-72cjogxz 4026 9 which which WDT cord-015369-72cjogxz 4026 10 patients patient NNS cord-015369-72cjogxz 4026 11 -and -and : cord-015369-72cjogxz 4026 12 for for IN cord-015369-72cjogxz 4026 13 what what WP cord-015369-72cjogxz 4026 14 reason reason NN cord-015369-72cjogxz 4026 15 -fail -fail : cord-015369-72cjogxz 4026 16 to to TO cord-015369-72cjogxz 4026 17 be be VB cord-015369-72cjogxz 4026 18 compliant compliant JJ cord-015369-72cjogxz 4026 19 , , , cord-015369-72cjogxz 4026 20 and and CC cord-015369-72cjogxz 4026 21 how how WRB cord-015369-72cjogxz 4026 22 long long RB cord-015369-72cjogxz 4026 23 it -PRON- PRP cord-015369-72cjogxz 4026 24 takes take VBZ cord-015369-72cjogxz 4026 25 until until IN cord-015369-72cjogxz 4026 26 they -PRON- PRP cord-015369-72cjogxz 4026 27 quit quit VBD cord-015369-72cjogxz 4026 28 AI AI NNP cord-015369-72cjogxz 4026 29 therapy therapy NN cord-015369-72cjogxz 4026 30 . . . cord-015369-72cjogxz 4027 1 Study study NN cord-015369-72cjogxz 4027 2 design design NN cord-015369-72cjogxz 4027 3 . . . cord-015369-72cjogxz 4028 1 Cariatide Cariatide NNP cord-015369-72cjogxz 4028 2 is be VBZ cord-015369-72cjogxz 4028 3 an an DT cord-015369-72cjogxz 4028 4 international international JJ cord-015369-72cjogxz 4028 5 , , , cord-015369-72cjogxz 4028 6 randomized randomized JJ cord-015369-72cjogxz 4028 7 , , , cord-015369-72cjogxz 4028 8 multicentre multicentre NNP cord-015369-72cjogxz 4028 9 observational observational JJ cord-015369-72cjogxz 4028 10 study study NN cord-015369-72cjogxz 4028 11 that that WDT cord-015369-72cjogxz 4028 12 will will MD cord-015369-72cjogxz 4028 13 include include VB cord-015369-72cjogxz 4028 14 approx approx NN cord-015369-72cjogxz 4028 15 . . . cord-015369-72cjogxz 4029 1 2600 2600 CD cord-015369-72cjogxz 4029 2 patients patient NNS cord-015369-72cjogxz 4029 3 from from IN cord-015369-72cjogxz 4029 4 more more JJR cord-015369-72cjogxz 4029 5 than than IN cord-015369-72cjogxz 4029 6 200 200 CD cord-015369-72cjogxz 4029 7 centers center NNS cord-015369-72cjogxz 4029 8 in in IN cord-015369-72cjogxz 4029 9 18 18 CD cord-015369-72cjogxz 4029 10 countries country NNS cord-015369-72cjogxz 4029 11 . . . cord-015369-72cjogxz 4030 1 Patients patient NNS cord-015369-72cjogxz 4030 2 will will MD cord-015369-72cjogxz 4030 3 be be VB cord-015369-72cjogxz 4030 4 randomized randomize VBN cord-015369-72cjogxz 4030 5 to to IN cord-015369-72cjogxz 4030 6 either either DT cord-015369-72cjogxz 4030 7 standard standard JJ cord-015369-72cjogxz 4030 8 adjuvant adjuvant NN cord-015369-72cjogxz 4030 9 AI ai NN cord-015369-72cjogxz 4030 10 therapy therapy NN cord-015369-72cjogxz 4030 11 or or CC cord-015369-72cjogxz 4030 12 to to IN cord-015369-72cjogxz 4030 13 standard standard JJ cord-015369-72cjogxz 4030 14 AI AI NNP cord-015369-72cjogxz 4030 15 therapy therapy NN cord-015369-72cjogxz 4030 16 plus plus CC cord-015369-72cjogxz 4030 17 additional additional JJ cord-015369-72cjogxz 4030 18 educational educational JJ cord-015369-72cjogxz 4030 19 material material NN cord-015369-72cjogxz 4030 20 , , , cord-015369-72cjogxz 4030 21 which which WDT cord-015369-72cjogxz 4030 22 will will MD cord-015369-72cjogxz 4030 23 provide provide VB cord-015369-72cjogxz 4030 24 information information NN cord-015369-72cjogxz 4030 25 about about IN cord-015369-72cjogxz 4030 26 attributes attribute NNS cord-015369-72cjogxz 4030 27 of of IN cord-015369-72cjogxz 4030 28 breast breast NN cord-015369-72cjogxz 4030 29 cancer cancer NN cord-015369-72cjogxz 4030 30 , , , cord-015369-72cjogxz 4030 31 the the DT cord-015369-72cjogxz 4030 32 risks risk NNS cord-015369-72cjogxz 4030 33 and and CC cord-015369-72cjogxz 4030 34 benefits benefit NNS cord-015369-72cjogxz 4030 35 of of IN cord-015369-72cjogxz 4030 36 endocrine endocrine JJ cord-015369-72cjogxz 4030 37 therapy therapy NN cord-015369-72cjogxz 4030 38 , , , cord-015369-72cjogxz 4030 39 the the DT cord-015369-72cjogxz 4030 40 risk risk NN cord-015369-72cjogxz 4030 41 of of IN cord-015369-72cjogxz 4030 42 relapse relapse NN cord-015369-72cjogxz 4030 43 and and CC cord-015369-72cjogxz 4030 44 management management NN cord-015369-72cjogxz 4030 45 of of IN cord-015369-72cjogxz 4030 46 long long JJ cord-015369-72cjogxz 4030 47 - - HYPH cord-015369-72cjogxz 4030 48 term term NN cord-015369-72cjogxz 4030 49 endocrine endocrine JJ cord-015369-72cjogxz 4030 50 treatment treatment NN cord-015369-72cjogxz 4030 51 and and CC cord-015369-72cjogxz 4030 52 its -PRON- PRP$ cord-015369-72cjogxz 4030 53 side side NN cord-015369-72cjogxz 4030 54 effects effect NNS cord-015369-72cjogxz 4030 55 . . . cord-015369-72cjogxz 4031 1 The the DT cord-015369-72cjogxz 4031 2 material material NN cord-015369-72cjogxz 4031 3 includes include VBZ cord-015369-72cjogxz 4031 4 questionnaires questionnaire NNS cord-015369-72cjogxz 4031 5 to to TO cord-015369-72cjogxz 4031 6 objectify objectify VB cord-015369-72cjogxz 4031 7 patient patient JJ cord-015369-72cjogxz 4031 8 's 's POS cord-015369-72cjogxz 4031 9 conception conception NN cord-015369-72cjogxz 4031 10 of of IN cord-015369-72cjogxz 4031 11 the the DT cord-015369-72cjogxz 4031 12 disease disease NN cord-015369-72cjogxz 4031 13 and and CC cord-015369-72cjogxz 4031 14 its -PRON- PRP$ cord-015369-72cjogxz 4031 15 treatment treatment NN cord-015369-72cjogxz 4031 16 . . . cord-015369-72cjogxz 4032 1 Conclusions conclusion NNS cord-015369-72cjogxz 4032 2 . . . cord-015369-72cjogxz 4033 1 Randomization randomization NN cord-015369-72cjogxz 4033 2 is be VBZ cord-015369-72cjogxz 4033 3 ongoing ongoing JJ cord-015369-72cjogxz 4033 4 and and CC cord-015369-72cjogxz 4033 5 will will MD cord-015369-72cjogxz 4033 6 be be VB cord-015369-72cjogxz 4033 7 finalized finalize VBN cord-015369-72cjogxz 4033 8 by by IN cord-015369-72cjogxz 4033 9 March March NNP cord-015369-72cjogxz 4033 10 2009 2009 CD cord-015369-72cjogxz 4033 11 ; ; : cord-015369-72cjogxz 4033 12 so so RB cord-015369-72cjogxz 4033 13 far far RB cord-015369-72cjogxz 4033 14 , , , cord-015369-72cjogxz 4033 15 68 68 CD cord-015369-72cjogxz 4033 16 patients patient NNS cord-015369-72cjogxz 4033 17 have have VBP cord-015369-72cjogxz 4033 18 been be VBN cord-015369-72cjogxz 4033 19 included include VBN cord-015369-72cjogxz 4033 20 in in IN cord-015369-72cjogxz 4033 21 Austria Austria NNP cord-015369-72cjogxz 4033 22 . . . cord-015369-72cjogxz 4034 1 The the DT cord-015369-72cjogxz 4034 2 study study NN cord-015369-72cjogxz 4034 3 will will MD cord-015369-72cjogxz 4034 4 help help VB cord-015369-72cjogxz 4034 5 to to TO cord-015369-72cjogxz 4034 6 identify identify VB cord-015369-72cjogxz 4034 7 patients patient NNS cord-015369-72cjogxz 4034 8 susceptible susceptible JJ cord-015369-72cjogxz 4034 9 to to IN cord-015369-72cjogxz 4034 10 compliance compliance NN cord-015369-72cjogxz 4034 11 failure failure NN cord-015369-72cjogxz 4034 12 , , , cord-015369-72cjogxz 4034 13 to to TO cord-015369-72cjogxz 4034 14 understand understand VB cord-015369-72cjogxz 4034 15 the the DT cord-015369-72cjogxz 4034 16 personal personal JJ cord-015369-72cjogxz 4034 17 reasons reason NNS cord-015369-72cjogxz 4034 18 of of IN cord-015369-72cjogxz 4034 19 compliance compliance NN cord-015369-72cjogxz 4034 20 or or CC cord-015369-72cjogxz 4034 21 non non JJ cord-015369-72cjogxz 4034 22 - - JJ cord-015369-72cjogxz 4034 23 adherence adherence JJ cord-015369-72cjogxz 4034 24 and and CC cord-015369-72cjogxz 4034 25 offering offering NN cord-015369-72cjogxz 4034 26 possibilities possibility NNS cord-015369-72cjogxz 4034 27 to to TO cord-015369-72cjogxz 4034 28 improve improve VB cord-015369-72cjogxz 4034 29 communication communication NN cord-015369-72cjogxz 4034 30 and and CC cord-015369-72cjogxz 4034 31 the the DT cord-015369-72cjogxz 4034 32 design design NN cord-015369-72cjogxz 4034 33 of of IN cord-015369-72cjogxz 4034 34 information information NN cord-015369-72cjogxz 4034 35 material material NN cord-015369-72cjogxz 4034 36 . . . cord-015369-72cjogxz 4035 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4035 2 . . . cord-015369-72cjogxz 4036 1 Das Das NNP cord-015369-72cjogxz 4036 2 70-Genexpressionsprofil 70-genexpressionsprofil CD cord-015369-72cjogxz 4037 1 ( ( -LRB- cord-015369-72cjogxz 4037 2 MammaPrint MammaPrint NNP cord-015369-72cjogxz 4037 3 ? ? . cord-015369-72cjogxz 4037 4 ? ? . cord-015369-72cjogxz 4037 5 ) ) -RRB- cord-015369-72cjogxz 4038 1 ist ist NNP cord-015369-72cjogxz 4038 2 als als NNP cord-015369-72cjogxz 4038 3 unabhängiger unabhängiger NNP cord-015369-72cjogxz 4038 4 prognostischer prognostischer NNP cord-015369-72cjogxz 4039 1 Marker Marker NNP cord-015369-72cjogxz 4039 2 beim beim NNP cord-015369-72cjogxz 4039 3 lymphknotennegativen lymphknotennegativen NNP cord-015369-72cjogxz 4039 4 und und XX cord-015369-72cjogxz 4040 1 -positiven -positiven NNP cord-015369-72cjogxz 4040 2 Mammakarzinom Mammakarzinom NNP cord-015369-72cjogxz 4040 3 etabliert etabliert NN cord-015369-72cjogxz 4040 4 . . . cord-015369-72cjogxz 4041 1 Der Der NNP cord-015369-72cjogxz 4041 2 prädiktive prädiktive NNP cord-015369-72cjogxz 4041 3 Wert Wert NNP cord-015369-72cjogxz 4041 4 für für IN cord-015369-72cjogxz 4041 5 das das NNP cord-015369-72cjogxz 4042 1 Ansprechen Ansprechen NNP cord-015369-72cjogxz 4042 2 auf auf NNP cord-015369-72cjogxz 4042 3 zusätzliche zusätzliche NNP cord-015369-72cjogxz 4042 4 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4042 5 gegenüber gegenüber NNP cord-015369-72cjogxz 4042 6 hormonaler hormonaler NN cord-015369-72cjogxz 4042 7 Therapie Therapie NNP cord-015369-72cjogxz 4042 8 alleine alleine NNP cord-015369-72cjogxz 4042 9 wird wird NNP cord-015369-72cjogxz 4042 10 sowohl sowohl NNP cord-015369-72cjogxz 4042 11 i i NNP cord-015369-72cjogxz 4043 1 m m NNP cord-015369-72cjogxz 4043 2 adjuvanten adjuvanten NNP cord-015369-72cjogxz 4043 3 als als NNP cord-015369-72cjogxz 4043 4 auch auch NNP cord-015369-72cjogxz 4043 5 i -PRON- PRP cord-015369-72cjogxz 4043 6 m be VBP cord-015369-72cjogxz 4043 7 neoadjuvanten neoadjuvanten NNP cord-015369-72cjogxz 4043 8 Setting Setting NNP cord-015369-72cjogxz 4043 9 präsentiert präsentiert NNP cord-015369-72cjogxz 4043 10 . . . cord-015369-72cjogxz 4044 1 Methodik Methodik NNP cord-015369-72cjogxz 4044 2 . . . cord-015369-72cjogxz 4045 1 1637 1637 CD cord-015369-72cjogxz 4046 1 Tumoren Tumoren NNP cord-015369-72cjogxz 4046 2 aus aus NNP cord-015369-72cjogxz 4046 3 7 7 CD cord-015369-72cjogxz 4046 4 Studien Studien NNP cord-015369-72cjogxz 4046 5 mit mit NNP cord-015369-72cjogxz 4046 6 bekannten bekannten NNP cord-015369-72cjogxz 4046 7 Tumorcharakteristika Tumorcharakteristika NNP cord-015369-72cjogxz 4046 8 und und IN cord-015369-72cjogxz 4047 1 Therapiedaten Therapiedaten NNP cord-015369-72cjogxz 4047 2 wurden wurden VBD cord-015369-72cjogxz 4047 3 unterteilt unterteilt VBN cord-015369-72cjogxz 4047 4 in in IN cord-015369-72cjogxz 4047 5 niedriges niedriges NNP cord-015369-72cjogxz 4047 6 oder oder NNP cord-015369-72cjogxz 4047 7 hohes hohes NNP cord-015369-72cjogxz 4047 8 Risiko Risiko NNP cord-015369-72cjogxz 4047 9 entsprechend entsprechend NN cord-015369-72cjogxz 4047 10 dem dem NNP cord-015369-72cjogxz 4047 11 MammaPrint MammaPrint NNP cord-015369-72cjogxz 4047 12 Profil Profil NNP cord-015369-72cjogxz 4047 13 . . . cord-015369-72cjogxz 4048 1 Die die VB cord-015369-72cjogxz 4048 2 mediane mediane NNP cord-015369-72cjogxz 4049 1 Nachbeobachtungszeit nachbeobachtungszeit JJ cord-015369-72cjogxz 4049 2 war war NN cord-015369-72cjogxz 4049 3 7,1 7,1 CD cord-015369-72cjogxz 4049 4 Jahre Jahre NNP cord-015369-72cjogxz 4049 5 . . . cord-015369-72cjogxz 4050 1 Der Der NNP cord-015369-72cjogxz 4050 2 Zusatznutzen Zusatznutzen NNP cord-015369-72cjogxz 4050 3 adjuvanter adjuvanter IN cord-015369-72cjogxz 4050 4 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4051 1 ( ( -LRB- cord-015369-72cjogxz 4051 2 CMF CMF NNP cord-015369-72cjogxz 4051 3 oder oder NNP cord-015369-72cjogxz 4051 4 Anthrazykline Anthrazykline NNP cord-015369-72cjogxz 4051 5 AE AE NNP cord-015369-72cjogxz 4051 6 Taxan Taxan NNP cord-015369-72cjogxz 4051 7 - - HYPH cord-015369-72cjogxz 4051 8 basiert basiert NNP cord-015369-72cjogxz 4051 9 ) ) -RRB- cord-015369-72cjogxz 4051 10 wurde wurde NNP cord-015369-72cjogxz 4051 11 mittels mittel NNS cord-015369-72cjogxz 4052 1 gepoolter gepoolter NNP cord-015369-72cjogxz 4052 2 Analyse Analyse NNP cord-015369-72cjogxz 4052 3 für für FW cord-015369-72cjogxz 4052 4 metastasenfreies metastasenfreies NNP cord-015369-72cjogxz 4052 5 ( ( -LRB- cord-015369-72cjogxz 4052 6 DDFS DDFS NNP cord-015369-72cjogxz 4052 7 ) ) -RRB- cord-015369-72cjogxz 4052 8 und und CC cord-015369-72cjogxz 4052 9 krankheitsspezifisches krankheitsspezifisches NNP cord-015369-72cjogxz 4052 10 Ü Ü NNP cord-015369-72cjogxz 4052 11 berleben berleben NNP cord-015369-72cjogxz 4052 12 ( ( -LRB- cord-015369-72cjogxz 4052 13 BCSS BCSS NNP cord-015369-72cjogxz 4052 14 ) ) -RRB- cord-015369-72cjogxz 4052 15 berechnet berechnet NNP cord-015369-72cjogxz 4052 16 . . . cord-015369-72cjogxz 4053 1 Zusätlich Zusätlich NNP cord-015369-72cjogxz 4053 2 wurde wurde NN cord-015369-72cjogxz 4053 3 die die VBP cord-015369-72cjogxz 4054 1 pathologische pathologische NNP cord-015369-72cjogxz 4054 2 Komplett Komplett NNP cord-015369-72cjogxz 4054 3 - - HYPH cord-015369-72cjogxz 4054 4 Remissionsrate Remissionsrate NNP cord-015369-72cjogxz 4054 5 ( ( -LRB- cord-015369-72cjogxz 4054 6 pCR pcr NN cord-015369-72cjogxz 4054 7 ) ) -RRB- cord-015369-72cjogxz 4054 8 bei bei NNP cord-015369-72cjogxz 4054 9 167 167 CD cord-015369-72cjogxz 4055 1 Patientinnen Patientinnen NNP cord-015369-72cjogxz 4055 2 nach nach NNP cord-015369-72cjogxz 4055 3 neoadjuvanter neoadjuvanter NN cord-015369-72cjogxz 4055 4 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4055 5 analysiert analysiert NN cord-015369-72cjogxz 4055 6 . . . cord-015369-72cjogxz 4056 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4056 2 . . . cord-015369-72cjogxz 4057 1 In in IN cord-015369-72cjogxz 4057 2 der der NNP cord-015369-72cjogxz 4057 3 adjuvanten adjuvanten NNP cord-015369-72cjogxz 4057 4 Analyse Analyse NNP cord-015369-72cjogxz 4057 5 wurden wurden VBD cord-015369-72cjogxz 4057 6 mittels mittels NNPS cord-015369-72cjogxz 4057 7 Genexpressionsprofil Genexpressionsprofil NNP cord-015369-72cjogxz 4058 1 47 47 CD cord-015369-72cjogxz 4058 2 % % NN cord-015369-72cjogxz 4058 3 der der NN cord-015369-72cjogxz 4058 4 Patientinnen Patientinnen NNP cord-015369-72cjogxz 4058 5 in in IN cord-015369-72cjogxz 4058 6 Niedrigrisiko Niedrigrisiko NNP cord-015369-72cjogxz 4058 7 und und IN cord-015369-72cjogxz 4058 8 53 53 CD cord-015369-72cjogxz 4058 9 % % NN cord-015369-72cjogxz 4058 10 in in IN cord-015369-72cjogxz 4058 11 Hochrisiko Hochrisiko NNP cord-015369-72cjogxz 4058 12 unterteilt unterteilt NN cord-015369-72cjogxz 4058 13 . . . cord-015369-72cjogxz 4059 1 349 349 CD cord-015369-72cjogxz 4059 2 Frauen Frauen NNP cord-015369-72cjogxz 4059 3 wurden wurden NNS cord-015369-72cjogxz 4059 4 mit mit NNP cord-015369-72cjogxz 4059 5 Hormontherapie Hormontherapie NNP cord-015369-72cjogxz 4059 6 alleine alleine NNP cord-015369-72cjogxz 4059 7 behandelt behandelt NNP cord-015369-72cjogxz 4059 8 und und IN cord-015369-72cjogxz 4059 9 226 226 CD cord-015369-72cjogxz 4059 10 zusätzlich zusätzlich NNP cord-015369-72cjogxz 4059 11 mit mit NNP cord-015369-72cjogxz 4059 12 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4059 13 . . . cord-015369-72cjogxz 4060 1 In in IN cord-015369-72cjogxz 4060 2 der der NNP cord-015369-72cjogxz 4060 3 Hochrisiko Hochrisiko NNP cord-015369-72cjogxz 4060 4 - - HYPH cord-015369-72cjogxz 4060 5 Gruppe Gruppe NNP cord-015369-72cjogxz 4060 6 zeigte zeigte NNP cord-015369-72cjogxz 4060 7 sich sich NNP cord-015369-72cjogxz 4060 8 ein ein NNP cord-015369-72cjogxz 4060 9 beträchtlicher beträchtlicher NNP cord-015369-72cjogxz 4060 10 Zusatznutzen Zusatznutzen NNP cord-015369-72cjogxz 4060 11 durch durch NNP cord-015369-72cjogxz 4060 12 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4060 13 : : : cord-015369-72cjogxz 4060 14 DDFS DDFS NNP cord-015369-72cjogxz 4060 15 hazard hazard NN cord-015369-72cjogxz 4060 16 ratio ratio NN cord-015369-72cjogxz 4060 17 ( ( -LRB- cord-015369-72cjogxz 4060 18 HR HR NNP cord-015369-72cjogxz 4060 19 ) ) -RRB- cord-015369-72cjogxz 4060 20 0,28 0,28 CD cord-015369-72cjogxz 4060 21 ( ( -LRB- cord-015369-72cjogxz 4060 22 0,14 0,14 CD cord-015369-72cjogxz 4060 23 - - HYPH cord-015369-72cjogxz 4060 24 0,56 0,56 CD cord-015369-72cjogxz 4060 25 ) ) -RRB- cord-015369-72cjogxz 4061 1 , , , cord-015369-72cjogxz 4061 2 p p NN cord-015369-72cjogxz 4061 3 < < XX cord-015369-72cjogxz 4061 4 0,01 0,01 XX cord-015369-72cjogxz 4061 5 und und RB cord-015369-72cjogxz 4062 1 BCSS BCSS NNP cord-015369-72cjogxz 4062 2 HR HR NNP cord-015369-72cjogxz 4062 3 0,17 0,17 CD cord-015369-72cjogxz 4062 4 ( ( -LRB- cord-015369-72cjogxz 4062 5 0,06 0,06 NN cord-015369-72cjogxz 4062 6 - - HYPH cord-015369-72cjogxz 4062 7 0,47 0,47 CD cord-015369-72cjogxz 4062 8 ) ) -RRB- cord-015369-72cjogxz 4063 1 , , , cord-015369-72cjogxz 4063 2 p p NN cord-015369-72cjogxz 4063 3 < < XX cord-015369-72cjogxz 4063 4 0,01 0,01 NNS cord-015369-72cjogxz 4063 5 . . . cord-015369-72cjogxz 4064 1 Bei Bei NNP cord-015369-72cjogxz 4064 2 multivariater multivariater NN cord-015369-72cjogxz 4064 3 Analyse Analyse NNP cord-015369-72cjogxz 4064 4 mit mit NNP cord-015369-72cjogxz 4064 5 bekannten bekannten JJ cord-015369-72cjogxz 4064 6 klinisch klinisch NNP cord-015369-72cjogxz 4064 7 - - HYPH cord-015369-72cjogxz 4064 8 pathologischen pathologischen NNP cord-015369-72cjogxz 4064 9 prognostischen prognostischen NNP cord-015369-72cjogxz 4065 1 Faktoren Faktoren NNP cord-015369-72cjogxz 4065 2 waren waren NNP cord-015369-72cjogxz 4065 3 die die VBP cord-015369-72cjogxz 4065 4 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4065 5 konstant konstant NNP cord-015369-72cjogxz 4065 6 . . . cord-015369-72cjogxz 4066 1 Demgegenüber Demgegenüber NNP cord-015369-72cjogxz 4066 2 zeigte zeigte TO cord-015369-72cjogxz 4066 3 die die VB cord-015369-72cjogxz 4066 4 Niedrigrisiko Niedrigrisiko NNP cord-015369-72cjogxz 4066 5 - - HYPH cord-015369-72cjogxz 4066 6 Gruppe Gruppe NNP cord-015369-72cjogxz 4066 7 keinen keinen NNP cord-015369-72cjogxz 4066 8 signifikanten signifikanten NNP cord-015369-72cjogxz 4066 9 Vorteil Vorteil NNP cord-015369-72cjogxz 4066 10 zusätzlicher zusätzlicher NNP cord-015369-72cjogxz 4067 1 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4067 2 gegenüber gegenüber NNP cord-015369-72cjogxz 4067 3 Hormontherapie Hormontherapie NNP cord-015369-72cjogxz 4067 4 alleine alleine NNP cord-015369-72cjogxz 4067 5 : : : cord-015369-72cjogxz 4068 1 DDFS DDFS NNP cord-015369-72cjogxz 4068 2 p p NNP cord-015369-72cjogxz 4068 3 ¼ ¼ NNP cord-015369-72cjogxz 4068 4 0,962 0,962 CD cord-015369-72cjogxz 4068 5 und und IN cord-015369-72cjogxz 4068 6 BCSS BCSS NNP cord-015369-72cjogxz 4068 7 p p NNP cord-015369-72cjogxz 4068 8 ¼ ¼ NNP cord-015369-72cjogxz 4068 9 0,472 0,472 CD cord-015369-72cjogxz 4068 10 . . . cord-015369-72cjogxz 4069 1 I -PRON- PRP cord-015369-72cjogxz 4069 2 m be VBP cord-015369-72cjogxz 4069 3 neoadjuvanten neoadjuvanten NNP cord-015369-72cjogxz 4070 1 Setting set VBG cord-015369-72cjogxz 4070 2 zeigte zeigte NNP cord-015369-72cjogxz 4070 3 sich sich NNP cord-015369-72cjogxz 4070 4 eine eine NNP cord-015369-72cjogxz 4070 5 pCR pCR NNP cord-015369-72cjogxz 4070 6 - - HYPH cord-015369-72cjogxz 4070 7 Rate Rate NNP cord-015369-72cjogxz 4070 8 von von NNP cord-015369-72cjogxz 4070 9 20 20 CD cord-015369-72cjogxz 4070 10 % % NN cord-015369-72cjogxz 4070 11 ( ( -LRB- cord-015369-72cjogxz 4070 12 29/144 29/144 CD cord-015369-72cjogxz 4070 13 ) ) -RRB- cord-015369-72cjogxz 4071 1 für für NNP cord-015369-72cjogxz 4071 2 die die VBP cord-015369-72cjogxz 4071 3 Hochrisiko Hochrisiko NNP cord-015369-72cjogxz 4071 4 - - HYPH cord-015369-72cjogxz 4071 5 Gruppe Gruppe NNP cord-015369-72cjogxz 4071 6 , , , cord-015369-72cjogxz 4072 1 während während JJ cord-015369-72cjogxz 4072 2 bei bei NNP cord-015369-72cjogxz 4072 3 Niedrigrisiko Niedrigrisiko NNP cord-015369-72cjogxz 4072 4 - - HYPH cord-015369-72cjogxz 4072 5 Patientinnen Patientinnen NNP cord-015369-72cjogxz 4072 6 keine keine NNP cord-015369-72cjogxz 4073 1 pCR pCR NNP cord-015369-72cjogxz 4073 2 ( ( -LRB- cord-015369-72cjogxz 4073 3 0/23 0/23 CD cord-015369-72cjogxz 4073 4 ) ) -RRB- cord-015369-72cjogxz 4074 1 beobachtet beobachtet NNP cord-015369-72cjogxz 4074 2 wurde wurde NNP cord-015369-72cjogxz 4074 3 . . . cord-015369-72cjogxz 4075 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4075 2 . . . cord-015369-72cjogxz 4076 1 Das Das NNP cord-015369-72cjogxz 4076 2 70-Genexpressionsprofil 70-genexpressionsprofil CD cord-015369-72cjogxz 4077 1 Mamma Mamma NNP cord-015369-72cjogxz 4077 2 - - HYPH cord-015369-72cjogxz 4077 3 Print Print NNP cord-015369-72cjogxz 4077 4 ist ist NN cord-015369-72cjogxz 4077 5 nicht nicht FW cord-015369-72cjogxz 4077 6 nur nur FW cord-015369-72cjogxz 4077 7 ein ein NNP cord-015369-72cjogxz 4078 1 unabhängiger unabhängiger NNP cord-015369-72cjogxz 4078 2 prognostischer prognostischer NNP cord-015369-72cjogxz 4078 3 Marker Marker NNP cord-015369-72cjogxz 4078 4 ; ; : cord-015369-72cjogxz 4078 5 zusätzlich zusätzlich NNP cord-015369-72cjogxz 4078 6 zeigt zeigt NNP cord-015369-72cjogxz 4078 7 sich sich NNP cord-015369-72cjogxz 4078 8 auch auch NNP cord-015369-72cjogxz 4078 9 der der NNP cord-015369-72cjogxz 4078 10 prädiktive prädiktive NNP cord-015369-72cjogxz 4078 11 Wert Wert NNP cord-015369-72cjogxz 4078 12 zusätzlicher zusätzlicher NN cord-015369-72cjogxz 4078 13 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4078 14 sowohl sowohl NNP cord-015369-72cjogxz 4078 15 i i NN cord-015369-72cjogxz 4079 1 m m NNP cord-015369-72cjogxz 4079 2 adjuvanten adjuvanten NNP cord-015369-72cjogxz 4079 3 als als NNP cord-015369-72cjogxz 4080 1 auch auch NNP cord-015369-72cjogxz 4080 2 i -PRON- PRP cord-015369-72cjogxz 4080 3 m be VBP cord-015369-72cjogxz 4080 4 neoadjuvanten neoadjuvanten NNP cord-015369-72cjogxz 4080 5 Setting setting NN cord-015369-72cjogxz 4080 6 . . . cord-015369-72cjogxz 4081 1 Während während JJ cord-015369-72cjogxz 4081 2 die die VBP cord-015369-72cjogxz 4081 3 Hochrisiko Hochrisiko NNP cord-015369-72cjogxz 4081 4 - - HYPH cord-015369-72cjogxz 4081 5 Gruppe Gruppe NNP cord-015369-72cjogxz 4081 6 signifikant signifikant NN cord-015369-72cjogxz 4081 7 von von NNP cord-015369-72cjogxz 4081 8 einer einer NNP cord-015369-72cjogxz 4082 1 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4082 2 zu zu XX cord-015369-72cjogxz 4083 1 profitieren profitieren NNP cord-015369-72cjogxz 4083 2 scheint scheint NNP cord-015369-72cjogxz 4083 3 , , , cord-015369-72cjogxz 4083 4 kann kann NNP cord-015369-72cjogxz 4083 5 ein ein NNP cord-015369-72cjogxz 4083 6 Niedrigrisiko Niedrigrisiko NNP cord-015369-72cjogxz 4083 7 - - HYPH cord-015369-72cjogxz 4083 8 Profil Profil NNP cord-015369-72cjogxz 4083 9 Patientinnen Patientinnen NNP cord-015369-72cjogxz 4083 10 selektieren selektieren NNP cord-015369-72cjogxz 4083 11 , , , cord-015369-72cjogxz 4083 12 die die VBP cord-015369-72cjogxz 4083 13 mit mit NNP cord-015369-72cjogxz 4083 14 hormonaler hormonaler NN cord-015369-72cjogxz 4083 15 Therapie Therapie NNP cord-015369-72cjogxz 4083 16 ausreichend ausreichend NN cord-015369-72cjogxz 4083 17 behandelt behandelt NNP cord-015369-72cjogxz 4083 18 erscheinen erscheinen NNP cord-015369-72cjogxz 4083 19 . . . cord-015369-72cjogxz 4084 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4084 2 . . . cord-015369-72cjogxz 4085 1 Angiosarkome Angiosarkome NNP cord-015369-72cjogxz 4085 2 sind sind NNP cord-015369-72cjogxz 4085 3 mit mit NNP cord-015369-72cjogxz 4085 4 nur nur NNP cord-015369-72cjogxz 4085 5 1 1 CD cord-015369-72cjogxz 4085 6 - - SYM cord-015369-72cjogxz 4085 7 2 2 CD cord-015369-72cjogxz 4085 8 % % NN cord-015369-72cjogxz 4086 1 aller aller NNP cord-015369-72cjogxz 4087 1 Weichteilsarkome Weichteilsarkome NNP cord-015369-72cjogxz 4087 2 sehr sehr JJ cord-015369-72cjogxz 4088 1 seltene seltene NNP cord-015369-72cjogxz 4088 2 maligne maligne NNP cord-015369-72cjogxz 4088 3 Tumore Tumore NNP cord-015369-72cjogxz 4088 4 . . . cord-015369-72cjogxz 4089 1 Ein Ein NNP cord-015369-72cjogxz 4089 2 zunehmendes zunehmende NNS cord-015369-72cjogxz 4090 1 Problem Problem NNP cord-015369-72cjogxz 4090 2 stellen stellen NNP cord-015369-72cjogxz 4090 3 die die VBP cord-015369-72cjogxz 4090 4 sekundären sekundären NNP cord-015369-72cjogxz 4090 5 Angiosarkome Angiosarkome NNP cord-015369-72cjogxz 4090 6 nach nach NNP cord-015369-72cjogxz 4090 7 brusterhaltender brusterhaltender NN cord-015369-72cjogxz 4090 8 Therapie Therapie NNP cord-015369-72cjogxz 4090 9 eines eines FW cord-015369-72cjogxz 4090 10 Mammakarzinoms Mammakarzinoms NNP cord-015369-72cjogxz 4090 11 und und IN cord-015369-72cjogxz 4090 12 postoperativer postoperativer NNP cord-015369-72cjogxz 4090 13 Bestrahlung Bestrahlung NNP cord-015369-72cjogxz 4090 14 dar dar NNP cord-015369-72cjogxz 4090 15 . . . cord-015369-72cjogxz 4091 1 Der Der NNP cord-015369-72cjogxz 4091 2 Erfolg Erfolg NNP cord-015369-72cjogxz 4091 3 einer einer NN cord-015369-72cjogxz 4091 4 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4091 5 ist ist NN cord-015369-72cjogxz 4091 6 zum zum NNP cord-015369-72cjogxz 4091 7 heutigen heutigen JJ cord-015369-72cjogxz 4091 8 Zeitpunkt Zeitpunkt NNP cord-015369-72cjogxz 4091 9 noch noch NNP cord-015369-72cjogxz 4091 10 nicht nicht NNP cord-015369-72cjogxz 4091 11 abzuschätzen abzuschätzen NNP cord-015369-72cjogxz 4091 12 , , , cord-015369-72cjogxz 4091 13 nur nur NNP cord-015369-72cjogxz 4091 14 eine eine NNP cord-015369-72cjogxz 4091 15 frühzeitige frühzeitige VBN cord-015369-72cjogxz 4091 16 Mastektomie Mastektomie NNP cord-015369-72cjogxz 4091 17 erscheint erscheint NNP cord-015369-72cjogxz 4091 18 die die VBP cord-015369-72cjogxz 4091 19 Prognose Prognose NNP cord-015369-72cjogxz 4091 20 zu zu NNP cord-015369-72cjogxz 4091 21 beeinflussen beeinflussen NNP cord-015369-72cjogxz 4091 22 . . . cord-015369-72cjogxz 4092 1 Wir Wir NNP cord-015369-72cjogxz 4092 2 berichten berichten NNP cord-015369-72cjogxz 4093 1 über über NNP cord-015369-72cjogxz 4093 2 zwei zwei NNP cord-015369-72cjogxz 4093 3 Patientinnen Patientinnen NNP cord-015369-72cjogxz 4093 4 , , , cord-015369-72cjogxz 4093 5 welche welche NNP cord-015369-72cjogxz 4093 6 nach nach NNP cord-015369-72cjogxz 4093 7 brusterhaltender brusterhaltender NNP cord-015369-72cjogxz 4093 8 Therapie Therapie NNP cord-015369-72cjogxz 4093 9 eines eines NNP cord-015369-72cjogxz 4094 1 Mammakarzinoms Mammakarzinoms NNP cord-015369-72cjogxz 4095 1 ein ein NNP cord-015369-72cjogxz 4095 2 sekundäres sekundäres NNP cord-015369-72cjogxz 4096 1 Angiosarkom Angiosarkom NNP cord-015369-72cjogxz 4096 2 der der NNP cord-015369-72cjogxz 4096 3 Brust Brust NNP cord-015369-72cjogxz 4096 4 entwickelten entwickelten NN cord-015369-72cjogxz 4096 5 . . . cord-015369-72cjogxz 4097 1 Kasuistik Kasuistik NNP cord-015369-72cjogxz 4097 2 . . . cord-015369-72cjogxz 4098 1 I -PRON- PRP cord-015369-72cjogxz 4099 1 m m LS cord-015369-72cjogxz 4099 2 ersten ersten NNP cord-015369-72cjogxz 4099 3 Fall Fall NNP cord-015369-72cjogxz 4099 4 wurde wurde VBD cord-015369-72cjogxz 4099 5 eine eine NNP cord-015369-72cjogxz 4099 6 74 74 CD cord-015369-72cjogxz 4099 7 jährige jährige NN cord-015369-72cjogxz 4099 8 Frau Frau NNP cord-015369-72cjogxz 4099 9 zur zur NNP cord-015369-72cjogxz 4099 10 Beurteilung Beurteilung NNP cord-015369-72cjogxz 4099 11 von von NNP cord-015369-72cjogxz 4099 12 neu neu NNP cord-015369-72cjogxz 4100 1 aufgetretenen aufgetretenen NNP cord-015369-72cjogxz 4100 2 vaskulären vaskulären NNP cord-015369-72cjogxz 4101 1 Läsionen Läsionen NNP cord-015369-72cjogxz 4101 2 an an DT cord-015369-72cjogxz 4101 3 der der NN cord-015369-72cjogxz 4101 4 Brust Brust NNP cord-015369-72cjogxz 4101 5 nach nach NN cord-015369-72cjogxz 4101 6 Quadrantenresektion Quadrantenresektion NNP cord-015369-72cjogxz 4101 7 und und XX cord-015369-72cjogxz 4102 1 Wächterlymphknotenbiopsie Wächterlymphknotenbiopsie NNP cord-015369-72cjogxz 4102 2 eines eine NNS cord-015369-72cjogxz 4103 1 Mammakarzinoms Mammakarzinoms NNP cord-015369-72cjogxz 4104 1 i -PRON- PRP cord-015369-72cjogxz 4104 2 m be VBP cord-015369-72cjogxz 4104 3 Stadium Stadium NNP cord-015369-72cjogxz 4105 1 I -PRON- PRP cord-015369-72cjogxz 4105 2 und und VBP cord-015369-72cjogxz 4105 3 postoperativer postoperativer NNP cord-015369-72cjogxz 4105 4 Radiatio Radiatio NNP cord-015369-72cjogxz 4105 5 zugewiesen zugewiesen NNP cord-015369-72cjogxz 4105 6 . . . cord-015369-72cjogxz 4106 1 Die die VB cord-015369-72cjogxz 4107 1 Stanzbiopsie Stanzbiopsie NNP cord-015369-72cjogxz 4107 2 der der NNP cord-015369-72cjogxz 4107 3 Läsion Läsion NNP cord-015369-72cjogxz 4107 4 ergab ergab NN cord-015369-72cjogxz 4108 1 ein ein NNP cord-015369-72cjogxz 4108 2 gering gering NNP cord-015369-72cjogxz 4108 3 differenziertes differenziertes NNP cord-015369-72cjogxz 4109 1 Angiosarkom Angiosarkom NNP cord-015369-72cjogxz 4109 2 . . . cord-015369-72cjogxz 4110 1 I -PRON- PRP cord-015369-72cjogxz 4111 1 m m LS cord-015369-72cjogxz 4111 2 präoperativen präoperativen NNP cord-015369-72cjogxz 4111 3 Staging Staging NNP cord-015369-72cjogxz 4111 4 konnten konnten NNP cord-015369-72cjogxz 4112 1 keine keine NNP cord-015369-72cjogxz 4112 2 Fernmetastasen Fernmetastasen NNP cord-015369-72cjogxz 4112 3 festgestellt festgestellt NNP cord-015369-72cjogxz 4113 1 werden werden NNP cord-015369-72cjogxz 4113 2 . . . cord-015369-72cjogxz 4114 1 Die die VB cord-015369-72cjogxz 4114 2 Patientin Patientin NNP cord-015369-72cjogxz 4114 3 wurde wurde NNP cord-015369-72cjogxz 4114 4 mastektomiert mastektomiert NNP cord-015369-72cjogxz 4114 5 und und NNP cord-015369-72cjogxz 4114 6 erhält erhält NNP cord-015369-72cjogxz 4114 7 adjuvant adjuvant NNP cord-015369-72cjogxz 4114 8 eine eine NNP cord-015369-72cjogxz 4114 9 Anthrazyklin Anthrazyklin NNP cord-015369-72cjogxz 4114 10 - - HYPH cord-015369-72cjogxz 4114 11 Monotherapie Monotherapie NNP cord-015369-72cjogxz 4114 12 . . . cord-015369-72cjogxz 4115 1 Bei Bei NNP cord-015369-72cjogxz 4115 2 einer einer NNP cord-015369-72cjogxz 4115 3 weiteren weiteren NNP cord-015369-72cjogxz 4115 4 77 77 CD cord-015369-72cjogxz 4116 1 jährigen jährigen NNP cord-015369-72cjogxz 4116 2 Patientin Patientin NNP cord-015369-72cjogxz 4116 3 wurde wurde NNP cord-015369-72cjogxz 4117 1 i i PRP cord-015369-72cjogxz 4118 1 m m NNP cord-015369-72cjogxz 4118 2 Rahmen Rahmen NNP cord-015369-72cjogxz 4118 3 der der NNP cord-015369-72cjogxz 4118 4 onkologischen onkologischen NNP cord-015369-72cjogxz 4119 1 Nachsorge Nachsorge NNP cord-015369-72cjogxz 4119 2 nach nach NN cord-015369-72cjogxz 4119 3 brusterhaltender brusterhaltender NN cord-015369-72cjogxz 4119 4 Therapie Therapie NNP cord-015369-72cjogxz 4120 1 und und IN cord-015369-72cjogxz 4120 2 adjuvanter adjuvanter NNP cord-015369-72cjogxz 4120 3 Radiatio Radiatio NNP cord-015369-72cjogxz 4120 4 eines eines NNP cord-015369-72cjogxz 4120 5 Mammakarzinoms Mammakarzinoms NNP cord-015369-72cjogxz 4121 1 i -PRON- PRP cord-015369-72cjogxz 4121 2 m be VBP cord-015369-72cjogxz 4121 3 Stadium Stadium NNP cord-015369-72cjogxz 4122 1 I -PRON- PRP cord-015369-72cjogxz 4122 2 ein ein VBP cord-015369-72cjogxz 4122 3 weit weit NNP cord-015369-72cjogxz 4122 4 fortgeschrittenes fortgeschrittenes NNPS cord-015369-72cjogxz 4122 5 Angiosarkom Angiosarkom NNP cord-015369-72cjogxz 4122 6 diagnostiziert diagnostiziert NNP cord-015369-72cjogxz 4122 7 . . . cord-015369-72cjogxz 4123 1 Der Der NNP cord-015369-72cjogxz 4123 2 Tumor Tumor NNP cord-015369-72cjogxz 4123 3 wuchs wuchs NN cord-015369-72cjogxz 4123 4 teilweise teilweise RB cord-015369-72cjogxz 4123 5 invasiv invasiv JJ cord-015369-72cjogxz 4123 6 in in IN cord-015369-72cjogxz 4123 7 die die NN cord-015369-72cjogxz 4124 1 Tiefe Tiefe NNP cord-015369-72cjogxz 4124 2 bis bis NNP cord-015369-72cjogxz 4124 3 zum zum NNP cord-015369-72cjogxz 4124 4 Perikard Perikard NNP cord-015369-72cjogxz 4124 5 und und IN cord-015369-72cjogxz 4124 6 bis bis NNP cord-015369-72cjogxz 4124 7 zur zur NNP cord-015369-72cjogxz 4124 8 Pleura Pleura NNP cord-015369-72cjogxz 4124 9 . . . cord-015369-72cjogxz 4125 1 Diese Diese NNP cord-015369-72cjogxz 4125 2 Patientin Patientin NNP cord-015369-72cjogxz 4125 3 erhielt erhielt NNP cord-015369-72cjogxz 4125 4 noch noch NNP cord-015369-72cjogxz 4125 5 2 2 CD cord-015369-72cjogxz 4126 1 Zyklen Zyklen NNP cord-015369-72cjogxz 4126 2 eines eines FW cord-015369-72cjogxz 4126 3 liposomalen liposomalen NNP cord-015369-72cjogxz 4126 4 Doxorubicins Doxorubicins NNP cord-015369-72cjogxz 4126 5 , , , cord-015369-72cjogxz 4126 6 verstarb verstarb NN cord-015369-72cjogxz 4126 7 aber aber NNP cord-015369-72cjogxz 4126 8 einen einen NNP cord-015369-72cjogxz 4126 9 Monat Monat NNP cord-015369-72cjogxz 4126 10 später später NNP cord-015369-72cjogxz 4126 11 . . . cord-015369-72cjogxz 4127 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4127 2 . . . cord-015369-72cjogxz 4128 1 Das Das NNP cord-015369-72cjogxz 4128 2 sekundäre sekundäre NNP cord-015369-72cjogxz 4128 3 Angiosarkom Angiosarkom NNP cord-015369-72cjogxz 4128 4 der der NNP cord-015369-72cjogxz 4128 5 Brust Brust NNP cord-015369-72cjogxz 4128 6 nach nach NN cord-015369-72cjogxz 4128 7 brusterhaltender brusterhaltender NNP cord-015369-72cjogxz 4128 8 Therapie Therapie NNP cord-015369-72cjogxz 4128 9 wird wird NNP cord-015369-72cjogxz 4128 10 immer immer NNP cord-015369-72cjogxz 4128 11 häufiger häufiger NNP cord-015369-72cjogxz 4128 12 beobachtet beobachtet NNP cord-015369-72cjogxz 4128 13 , , , cord-015369-72cjogxz 4128 14 da da NNP cord-015369-72cjogxz 4128 15 heute heute NNP cord-015369-72cjogxz 4129 1 Mammakarzinome Mammakarzinome NNP cord-015369-72cjogxz 4129 2 zunehmend zunehmend NNP cord-015369-72cjogxz 4129 3 brusterhaltend brusterhaltend NNP cord-015369-72cjogxz 4129 4 operiert operiert NNP cord-015369-72cjogxz 4129 5 werden werden NNP cord-015369-72cjogxz 4129 6 . . . cord-015369-72cjogxz 4130 1 Diese diese JJ cord-015369-72cjogxz 4130 2 ehemals ehemal NNS cord-015369-72cjogxz 4130 3 seltene seltene JJ cord-015369-72cjogxz 4130 4 Erkrankung Erkrankung NNP cord-015369-72cjogxz 4130 5 sollte sollte NNP cord-015369-72cjogxz 4130 6 nicht nicht NNP cord-015369-72cjogxz 4130 7 unterschätzt unterschätzt NNP cord-015369-72cjogxz 4130 8 werden werden NNP cord-015369-72cjogxz 4130 9 . . . cord-015369-72cjogxz 4131 1 Früherkennung früherkennung NN cord-015369-72cjogxz 4131 2 ist ist NN cord-015369-72cjogxz 4131 3 die die VBP cord-015369-72cjogxz 4131 4 einzige einzige JJ cord-015369-72cjogxz 4131 5 Möglichkeit Möglichkeit NNP cord-015369-72cjogxz 4131 6 , , , cord-015369-72cjogxz 4131 7 die die VB cord-015369-72cjogxz 4131 8 Ü ü NN cord-015369-72cjogxz 4131 9 berlebensraten berlebensraten NN cord-015369-72cjogxz 4131 10 dieser dieser NNP cord-015369-72cjogxz 4131 11 Erkrankung Erkrankung NNP cord-015369-72cjogxz 4131 12 zu zu NNP cord-015369-72cjogxz 4131 13 verbessern verbessern NNP cord-015369-72cjogxz 4131 14 . . . cord-015369-72cjogxz 4132 1 Zur Zur NNP cord-015369-72cjogxz 4132 2 Anwendung Anwendung NNP cord-015369-72cjogxz 4132 3 der der NN cord-015369-72cjogxz 4132 4 intraoperativen intraoperativen NNP cord-015369-72cjogxz 4133 1 Sonographie Sonographie NNP cord-015369-72cjogxz 4133 2 bei bei NNP cord-015369-72cjogxz 4133 3 der der NNP cord-015369-72cjogxz 4133 4 chirurgischen chirurgischen NNP cord-015369-72cjogxz 4133 5 Behandlung Behandlung NNP cord-015369-72cjogxz 4133 6 des des FW cord-015369-72cjogxz 4133 7 Mammakarzinoms Mammakarzinoms NNP cord-015369-72cjogxz 4133 8 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4133 9 . . . cord-015369-72cjogxz 4134 1 Mammakarzinome Mammakarzinome NNP cord-015369-72cjogxz 4134 2 werden werden NNP cord-015369-72cjogxz 4134 3 in in IN cord-015369-72cjogxz 4134 4 den den NNP cord-015369-72cjogxz 4134 5 letzten letzten NNP cord-015369-72cjogxz 4134 6 Jahren Jahren NNP cord-015369-72cjogxz 4134 7 zunehmend zunehmend NNP cord-015369-72cjogxz 4134 8 in in IN cord-015369-72cjogxz 4134 9 einem einem NNP cord-015369-72cjogxz 4134 10 frühen frühen NNP cord-015369-72cjogxz 4134 11 Stadium Stadium NNP cord-015369-72cjogxz 4134 12 mit mit NNP cord-015369-72cjogxz 4134 13 nicht nicht NNP cord-015369-72cjogxz 4134 14 oder oder NNP cord-015369-72cjogxz 4134 15 unsicher unsicher NNP cord-015369-72cjogxz 4134 16 tastbaren tastbaren NNP cord-015369-72cjogxz 4134 17 Tumoren Tumoren NNP cord-015369-72cjogxz 4134 18 entdeckt entdeckt NNP cord-015369-72cjogxz 4134 19 . . . cord-015369-72cjogxz 4135 1 I -PRON- PRP cord-015369-72cjogxz 4135 2 m be VBP cord-015369-72cjogxz 4136 1 Ultraschall Ultraschall NNP cord-015369-72cjogxz 4136 2 sind sind NNP cord-015369-72cjogxz 4137 1 bis bis NNP cord-015369-72cjogxz 4137 2 zu zu NNP cord-015369-72cjogxz 4137 3 95 95 CD cord-015369-72cjogxz 4137 4 % % NN cord-015369-72cjogxz 4138 1 aller aller NNP cord-015369-72cjogxz 4138 2 Mammakarzinome Mammakarzinome NNP cord-015369-72cjogxz 4138 3 gut gut NN cord-015369-72cjogxz 4138 4 sichtbar sichtbar NNP cord-015369-72cjogxz 4138 5 und und IN cord-015369-72cjogxz 4138 6 abgrenzbar abgrenzbar NN cord-015369-72cjogxz 4138 7 . . . cord-015369-72cjogxz 4139 1 Mit Mit NNP cord-015369-72cjogxz 4139 2 Hilfe Hilfe NNP cord-015369-72cjogxz 4139 3 der der NNP cord-015369-72cjogxz 4139 4 intraoperativen intraoperativen NNP cord-015369-72cjogxz 4140 1 Anwendung Anwendung NNP cord-015369-72cjogxz 4140 2 des des FW cord-015369-72cjogxz 4140 3 Ultraschalls Ultraschalls NNP cord-015369-72cjogxz 4141 1 durch durch NNP cord-015369-72cjogxz 4141 2 den den NNP cord-015369-72cjogxz 4141 3 Chirurgen Chirurgen NNP cord-015369-72cjogxz 4141 4 selbst selbst NNP cord-015369-72cjogxz 4141 5 können können NNP cord-015369-72cjogxz 4141 6 der der NNP cord-015369-72cjogxz 4141 7 Patienten Patienten NNP cord-015369-72cjogxz 4141 8 die die VBP cord-015369-72cjogxz 4141 9 unangenehme unangenehme NNP cord-015369-72cjogxz 4141 10 präoperative präoperative NNP cord-015369-72cjogxz 4142 1 Nadelmarkierung Nadelmarkierung NNP cord-015369-72cjogxz 4142 2 erspart erspart NNP cord-015369-72cjogxz 4143 1 werden werden NNP cord-015369-72cjogxz 4143 2 , , , cord-015369-72cjogxz 4143 3 zudem zudem NNP cord-015369-72cjogxz 4143 4 bietet bietet NNP cord-015369-72cjogxz 4143 5 sie sie NNP cord-015369-72cjogxz 4143 6 neben neben NNP cord-015369-72cjogxz 4144 1 vielen vielen NNP cord-015369-72cjogxz 4144 2 organisatorischen organisatorischen NNP cord-015369-72cjogxz 4144 3 Vorteilen Vorteilen NNP cord-015369-72cjogxz 4144 4 auch auch NNP cord-015369-72cjogxz 4144 5 eine eine NNP cord-015369-72cjogxz 4144 6 wertvolle wertvolle NN cord-015369-72cjogxz 4145 1 Orientierung Orientierung NNP cord-015369-72cjogxz 4145 2 bei bei NNP cord-015369-72cjogxz 4145 3 der der NNP cord-015369-72cjogxz 4145 4 Tumorektomie Tumorektomie NNP cord-015369-72cjogxz 4145 5 . . . cord-015369-72cjogxz 4146 1 Methodik Methodik NNP cord-015369-72cjogxz 4146 2 . . . cord-015369-72cjogxz 4147 1 Zwischen Zwischen NNP cord-015369-72cjogxz 4147 2 Juli Juli NNP cord-015369-72cjogxz 4147 3 2001 2001 CD cord-015369-72cjogxz 4147 4 und und IN cord-015369-72cjogxz 4147 5 Dezember Dezember NNP cord-015369-72cjogxz 4147 6 2008 2008 CD cord-015369-72cjogxz 4147 7 wurden wurden NNS cord-015369-72cjogxz 4147 8 am be VBP cord-015369-72cjogxz 4147 9 Landeskrankenhaus Landeskrankenhaus NNP cord-015369-72cjogxz 4147 10 Feldkirch Feldkirch NNP cord-015369-72cjogxz 4147 11 861 861 CD cord-015369-72cjogxz 4147 12 Mammakarzinome Mammakarzinome NNP cord-015369-72cjogxz 4147 13 operativ operativ NN cord-015369-72cjogxz 4147 14 behandelt behandelt NNP cord-015369-72cjogxz 4147 15 . . . cord-015369-72cjogxz 4148 1 In in IN cord-015369-72cjogxz 4148 2 617 617 CD cord-015369-72cjogxz 4148 3 Fällen Fällen NNP cord-015369-72cjogxz 4148 4 ( ( -LRB- cord-015369-72cjogxz 4148 5 72 72 CD cord-015369-72cjogxz 4148 6 % % NN cord-015369-72cjogxz 4148 7 ) ) -RRB- cord-015369-72cjogxz 4148 8 erfolgte erfolgte NN cord-015369-72cjogxz 4148 9 primär primär XX cord-015369-72cjogxz 4148 10 eine eine NNP cord-015369-72cjogxz 4148 11 Tumorektomie Tumorektomie NNP cord-015369-72cjogxz 4148 12 , , , cord-015369-72cjogxz 4148 13 intraoperativ intraoperativ NNP cord-015369-72cjogxz 4148 14 kam kam NNP cord-015369-72cjogxz 4148 15 der der NN cord-015369-72cjogxz 4148 16 Ultraschall Ultraschall NNP cord-015369-72cjogxz 4148 17 bei bei NNP cord-015369-72cjogxz 4148 18 434 434 CD cord-015369-72cjogxz 4148 19 oder oder NN cord-015369-72cjogxz 4148 20 70 70 CD cord-015369-72cjogxz 4148 21 % % NN cord-015369-72cjogxz 4148 22 aller aller NNP cord-015369-72cjogxz 4148 23 dieser dieser NNP cord-015369-72cjogxz 4148 24 Eingriffe Eingriffe NNP cord-015369-72cjogxz 4148 25 zur zur NNP cord-015369-72cjogxz 4148 26 Anwendung Anwendung NNP cord-015369-72cjogxz 4148 27 . . . cord-015369-72cjogxz 4149 1 In in IN cord-015369-72cjogxz 4149 2 192 192 CD cord-015369-72cjogxz 4149 3 Fällen Fällen NNP cord-015369-72cjogxz 4149 4 ( ( -LRB- cord-015369-72cjogxz 4149 5 44 44 CD cord-015369-72cjogxz 4149 6 % % NN cord-015369-72cjogxz 4149 7 ) ) -RRB- cord-015369-72cjogxz 4149 8 war war NN cord-015369-72cjogxz 4149 9 der der NN cord-015369-72cjogxz 4149 10 Tumor Tumor NNP cord-015369-72cjogxz 4149 11 nicht nicht NNP cord-015369-72cjogxz 4149 12 tastbar tastbar NNP cord-015369-72cjogxz 4149 13 , , , cord-015369-72cjogxz 4149 14 bei bei NNP cord-015369-72cjogxz 4149 15 den den NNP cord-015369-72cjogxz 4149 16 restlichen restlichen NNP cord-015369-72cjogxz 4149 17 unsicher unsicher NNP cord-015369-72cjogxz 4149 18 . . . cord-015369-72cjogxz 4150 1 Intraoperativ intraoperativ JJ cord-015369-72cjogxz 4150 2 erfolgte erfolgte NN cord-015369-72cjogxz 4150 3 die die VBP cord-015369-72cjogxz 4150 4 Begutachtung Begutachtung NNP cord-015369-72cjogxz 4150 5 der der NNP cord-015369-72cjogxz 4150 6 Schnittränder Schnittränder NNP cord-015369-72cjogxz 4150 7 allein allein NNP cord-015369-72cjogxz 4150 8 makroskopisch makroskopisch NNP cord-015369-72cjogxz 4150 9 durch durch NNP cord-015369-72cjogxz 4150 10 den den NNP cord-015369-72cjogxz 4150 11 Pathologen Pathologen NNP cord-015369-72cjogxz 4150 12 , , , cord-015369-72cjogxz 4150 13 nicht nicht NNP cord-015369-72cjogxz 4150 14 jedoch jedoch NNP cord-015369-72cjogxz 4150 15 histologisch histologisch NNP cord-015369-72cjogxz 4150 16 . . . cord-015369-72cjogxz 4151 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4151 2 . . . cord-015369-72cjogxz 4152 1 Nicht Nicht NNP cord-015369-72cjogxz 4152 2 oder oder NNP cord-015369-72cjogxz 4152 3 unsicher unsicher NNP cord-015369-72cjogxz 4152 4 tastbare tastbare NNP cord-015369-72cjogxz 4152 5 Tumore Tumore NNP cord-015369-72cjogxz 4152 6 konnten konnten NNP cord-015369-72cjogxz 4152 7 in in IN cord-015369-72cjogxz 4152 8 allen allen NNP cord-015369-72cjogxz 4152 9 bis bis NNP cord-015369-72cjogxz 4152 10 auf auf NNP cord-015369-72cjogxz 4152 11 2 2 CD cord-015369-72cjogxz 4152 12 Fälle Fälle NNP cord-015369-72cjogxz 4152 13 sicher sicher NNP cord-015369-72cjogxz 4152 14 aufgefunden aufgefunden NNP cord-015369-72cjogxz 4152 15 werden werden NNP cord-015369-72cjogxz 4152 16 . . . cord-015369-72cjogxz 4153 1 Metachrone Metachrone NNP cord-015369-72cjogxz 4153 2 Nachresektionen Nachresektionen NNP cord-015369-72cjogxz 4153 3 waren waren NNP cord-015369-72cjogxz 4154 1 68 68 CD cord-015369-72cjogxz 4154 2 Mal mal JJ cord-015369-72cjogxz 4154 3 ( ( -LRB- cord-015369-72cjogxz 4154 4 16 16 CD cord-015369-72cjogxz 4154 5 % % NN cord-015369-72cjogxz 4154 6 ) ) -RRB- cord-015369-72cjogxz 4154 7 erforderlich erforderlich NNP cord-015369-72cjogxz 4154 8 . . . cord-015369-72cjogxz 4155 1 Davon Davon NNP cord-015369-72cjogxz 4155 2 fanden fanden NNP cord-015369-72cjogxz 4155 3 sich sich NNP cord-015369-72cjogxz 4155 4 in in IN cord-015369-72cjogxz 4155 5 31 31 CD cord-015369-72cjogxz 4155 6 Fällen Fällen NNP cord-015369-72cjogxz 4155 7 ( ( -LRB- cord-015369-72cjogxz 4155 8 46 46 CD cord-015369-72cjogxz 4155 9 % % NN cord-015369-72cjogxz 4155 10 ) ) -RRB- cord-015369-72cjogxz 4156 1 i -PRON- PRP cord-015369-72cjogxz 4156 2 m be VBP cord-015369-72cjogxz 4157 1 Nachresektat Nachresektat NNP cord-015369-72cjogxz 4157 2 keine keine NNP cord-015369-72cjogxz 4158 1 Hinweise Hinweise NNP cord-015369-72cjogxz 4158 2 mehr mehr NNP cord-015369-72cjogxz 4158 3 für für JJ cord-015369-72cjogxz 4158 4 malignes malignes NNP cord-015369-72cjogxz 4158 5 Gewebe Gewebe NNP cord-015369-72cjogxz 4158 6 , , , cord-015369-72cjogxz 4158 7 in in IN cord-015369-72cjogxz 4158 8 17 17 CD cord-015369-72cjogxz 4158 9 Fällen Fällen NNP cord-015369-72cjogxz 4158 10 ( ( -LRB- cord-015369-72cjogxz 4158 11 25 25 CD cord-015369-72cjogxz 4158 12 % % NN cord-015369-72cjogxz 4158 13 ) ) -RRB- cord-015369-72cjogxz 4158 14 in in IN cord-015369-72cjogxz 4158 15 - - HYPH cord-015369-72cjogxz 4158 16 situ situ NN cord-015369-72cjogxz 4158 17 - - : cord-015369-72cjogxz 4158 18 Formationen Formationen NNP cord-015369-72cjogxz 4158 19 , , , cord-015369-72cjogxz 4158 20 20 20 CD cord-015369-72cjogxz 4158 21 Mal mal JJ cord-015369-72cjogxz 4158 22 ( ( -LRB- cord-015369-72cjogxz 4158 23 29 29 CD cord-015369-72cjogxz 4158 24 % % NN cord-015369-72cjogxz 4158 25 ) ) -RRB- cord-015369-72cjogxz 4158 26 in in IN cord-015369-72cjogxz 4158 27 - - HYPH cord-015369-72cjogxz 4158 28 situ situ NN cord-015369-72cjogxz 4158 29 - - HYPH cord-015369-72cjogxz 4158 30 zusammen zusammen NNP cord-015369-72cjogxz 4158 31 mit mit NNP cord-015369-72cjogxz 4158 32 invasiven invasiven NNP cord-015369-72cjogxz 4158 33 Karzinomstrukturen Karzinomstrukturen NNP cord-015369-72cjogxz 4158 34 . . . cord-015369-72cjogxz 4159 1 Bei Bei NNP cord-015369-72cjogxz 4159 2 den den NNP cord-015369-72cjogxz 4160 1 nicht nicht NNP cord-015369-72cjogxz 4160 2 auffindbaren auffindbaren NNP cord-015369-72cjogxz 4161 1 Tumoren Tumoren NNP cord-015369-72cjogxz 4161 2 handelte handelte NNP cord-015369-72cjogxz 4161 3 es es NNP cord-015369-72cjogxz 4161 4 sich sich NNP cord-015369-72cjogxz 4161 5 um um UH cord-015369-72cjogxz 4161 6 T1a T1a NNP cord-015369-72cjogxz 4162 1 und und NNP cord-015369-72cjogxz 4163 1 T1b T1b NNP cord-015369-72cjogxz 4163 2 - - HYPH cord-015369-72cjogxz 4163 3 Tumore Tumore NNP cord-015369-72cjogxz 4163 4 , , , cord-015369-72cjogxz 4163 5 die die VB cord-015369-72cjogxz 4163 6 bereits bereit NNS cord-015369-72cjogxz 4164 1 durch durch NNP cord-015369-72cjogxz 4164 2 die die NNP cord-015369-72cjogxz 4165 1 Stanzbiopsie Stanzbiopsie NNP cord-015369-72cjogxz 4165 2 schon schon NNP cord-015369-72cjogxz 4165 3 großteils großteils NNP cord-015369-72cjogxz 4165 4 entfernt entfernt NNP cord-015369-72cjogxz 4165 5 waren waren NNP cord-015369-72cjogxz 4165 6 . . . cord-015369-72cjogxz 4166 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4166 2 . . . cord-015369-72cjogxz 4167 1 Der der VB cord-015369-72cjogxz 4167 2 intraoperative intraoperative JJ cord-015369-72cjogxz 4167 3 Ultraschall Ultraschall NNP cord-015369-72cjogxz 4167 4 in in IN cord-015369-72cjogxz 4167 5 der der NNP cord-015369-72cjogxz 4167 6 Hand Hand NNP cord-015369-72cjogxz 4167 7 des des NNP cord-015369-72cjogxz 4167 8 Chirurgen Chirurgen NNP cord-015369-72cjogxz 4167 9 hat hat NN cord-015369-72cjogxz 4167 10 sich sich NN cord-015369-72cjogxz 4167 11 zum zum NNP cord-015369-72cjogxz 4167 12 Auffinden Auffinden NNP cord-015369-72cjogxz 4167 13 von von NNP cord-015369-72cjogxz 4167 14 nicht nicht NNP cord-015369-72cjogxz 4167 15 tastbaren tastbaren NNP cord-015369-72cjogxz 4167 16 Tumoren Tumoren NNP cord-015369-72cjogxz 4168 1 und und NNP cord-015369-72cjogxz 4168 2 zur zur NNP cord-015369-72cjogxz 4168 3 Orientierung Orientierung NNP cord-015369-72cjogxz 4168 4 bei bei NNP cord-015369-72cjogxz 4168 5 der der NNP cord-015369-72cjogxz 4168 6 Tumorektomie Tumorektomie NNP cord-015369-72cjogxz 4168 7 bewährt bewährt NN cord-015369-72cjogxz 4168 8 . . . cord-015369-72cjogxz 4169 1 Die Die NNP cord-015369-72cjogxz 4169 2 Ausdehnung Ausdehnung NNP cord-015369-72cjogxz 4169 3 des des FW cord-015369-72cjogxz 4169 4 Tumorgeschehens Tumorgeschehens NNP cord-015369-72cjogxz 4169 5 wird wird JJ cord-015369-72cjogxz 4169 6 jedoch jedoch NNP cord-015369-72cjogxz 4169 7 relativ relativ NNP cord-015369-72cjogxz 4169 8 häufig häufig NNP cord-015369-72cjogxz 4169 9 unterschätzt unterschätzt JJ cord-015369-72cjogxz 4169 10 , , , cord-015369-72cjogxz 4170 1 insbesondere insbesondere NNP cord-015369-72cjogxz 4170 2 was be VBD cord-015369-72cjogxz 4170 3 die die JJ cord-015369-72cjogxz 4170 4 in in IN cord-015369-72cjogxz 4170 5 - - HYPH cord-015369-72cjogxz 4170 6 situ situ NN cord-015369-72cjogxz 4170 7 - - : cord-015369-72cjogxz 4170 8 Anteile Anteile NNP cord-015369-72cjogxz 4170 9 betrifft betrifft NNP cord-015369-72cjogxz 4170 10 . . . cord-015369-72cjogxz 4171 1 Da Da NNP cord-015369-72cjogxz 4171 2 das das NNP cord-015369-72cjogxz 4171 3 brusterhaltende brusterhaltende NNP cord-015369-72cjogxz 4171 4 Konzept Konzept NNP cord-015369-72cjogxz 4172 1 i -PRON- PRP cord-015369-72cjogxz 4172 2 m be VBP cord-015369-72cjogxz 4172 3 Mittelpunkt Mittelpunkt NNP cord-015369-72cjogxz 4172 4 der der NNP cord-015369-72cjogxz 4172 5 chirurgischen chirurgischen NNP cord-015369-72cjogxz 4172 6 Versorgung Versorgung NNP cord-015369-72cjogxz 4172 7 des des FW cord-015369-72cjogxz 4172 8 Mammakarzinoms Mammakarzinoms NNP cord-015369-72cjogxz 4172 9 steht steht NNP cord-015369-72cjogxz 4172 10 , , , cord-015369-72cjogxz 4172 11 stellt stellt NNP cord-015369-72cjogxz 4172 12 die die VBP cord-015369-72cjogxz 4172 13 postoperative postoperative JJ cord-015369-72cjogxz 4172 14 Bestrahlung Bestrahlung NNP cord-015369-72cjogxz 4172 15 einen einen NNP cord-015369-72cjogxz 4172 16 Goldstandard Goldstandard NNP cord-015369-72cjogxz 4172 17 dar dar NNP cord-015369-72cjogxz 4172 18 . . . cord-015369-72cjogxz 4173 1 Strahlungsinduzierte Strahlungsinduzierte NNP cord-015369-72cjogxz 4173 2 Tumore Tumore NNP cord-015369-72cjogxz 4173 3 als als NN cord-015369-72cjogxz 4173 4 Folge folge NN cord-015369-72cjogxz 4173 5 dieser dieser NN cord-015369-72cjogxz 4173 6 Therapie Therapie NNP cord-015369-72cjogxz 4173 7 sind sind NNP cord-015369-72cjogxz 4173 8 eine eine NNP cord-015369-72cjogxz 4173 9 absolute absolute JJ cord-015369-72cjogxz 4173 10 Rarität Rarität NNPS cord-015369-72cjogxz 4173 11 . . . cord-015369-72cjogxz 4174 1 Wir Wir NNP cord-015369-72cjogxz 4174 2 möchten möchten NNP cord-015369-72cjogxz 4174 3 2 2 CD cord-015369-72cjogxz 4174 4 Patientinnen Patientinnen NNP cord-015369-72cjogxz 4174 5 präsentieren präsentieren NNP cord-015369-72cjogxz 4174 6 . . . cord-015369-72cjogxz 4175 1 Beim Beim NNP cord-015369-72cjogxz 4175 2 ersten ersten NNP cord-015369-72cjogxz 4175 3 Fall fall NN cord-015369-72cjogxz 4175 4 handelt handelt RB cord-015369-72cjogxz 4176 1 es es NNP cord-015369-72cjogxz 4176 2 sich sich NNP cord-015369-72cjogxz 4176 3 um um UH cord-015369-72cjogxz 4176 4 eine eine NNP cord-015369-72cjogxz 4176 5 59 59 CD cord-015369-72cjogxz 4176 6 jährige jährige NNP cord-015369-72cjogxz 4176 7 Patientin Patientin NNP cord-015369-72cjogxz 4176 8 , , , cord-015369-72cjogxz 4176 9 die die VB cord-015369-72cjogxz 4176 10 vor vor NNP cord-015369-72cjogxz 4176 11 15 15 CD cord-015369-72cjogxz 4176 12 Jahren Jahren NNP cord-015369-72cjogxz 4176 13 wegen wegen NNP cord-015369-72cjogxz 4176 14 eines eines NNP cord-015369-72cjogxz 4176 15 invasiv invasiv NNP cord-015369-72cjogxz 4176 16 duktalen duktalen NNP cord-015369-72cjogxz 4176 17 Mammacarzinoms Mammacarzinoms NNP cord-015369-72cjogxz 4176 18 nach nach NNP cord-015369-72cjogxz 4176 19 einer einer NNP cord-015369-72cjogxz 4176 20 brusterhaltenden brusterhaltenden NNP cord-015369-72cjogxz 4176 21 Operation Operation NNP cord-015369-72cjogxz 4176 22 einer einer NNP cord-015369-72cjogxz 4176 23 Bestrahlung Bestrahlung NNP cord-015369-72cjogxz 4176 24 zugeführt zugeführt NNP cord-015369-72cjogxz 4176 25 wurde wurde NNP cord-015369-72cjogxz 4176 26 . . . cord-015369-72cjogxz 4177 1 Vor Vor NNP cord-015369-72cjogxz 4177 2 4 4 CD cord-015369-72cjogxz 4177 3 Monaten Monaten NNP cord-015369-72cjogxz 4177 4 wurde wurde VBD cord-015369-72cjogxz 4177 5 eine eine NNP cord-015369-72cjogxz 4177 6 derbe derbe NNP cord-015369-72cjogxz 4178 1 Struktur Struktur NNP cord-015369-72cjogxz 4178 2 i -PRON- PRP cord-015369-72cjogxz 4178 3 m be VBP cord-015369-72cjogxz 4178 4 Bereich Bereich NNP cord-015369-72cjogxz 4178 5 der der NNP cord-015369-72cjogxz 4178 6 OP OP NNP cord-015369-72cjogxz 4178 7 Narbe Narbe NNP cord-015369-72cjogxz 4178 8 entfernt entfernt NNP cord-015369-72cjogxz 4178 9 . . . cord-015369-72cjogxz 4179 1 Die die VB cord-015369-72cjogxz 4179 2 Histologie Histologie NNP cord-015369-72cjogxz 4179 3 ergibt ergibt NNP cord-015369-72cjogxz 4179 4 ein ein NNP cord-015369-72cjogxz 4179 5 Angiosarkom Angiosarkom NNP cord-015369-72cjogxz 4179 6 . . . cord-015369-72cjogxz 4180 1 Nach Nach NNP cord-015369-72cjogxz 4180 2 Abklärung Abklärung NNP cord-015369-72cjogxz 4181 1 wurde wurde NNP cord-015369-72cjogxz 4181 2 diese diese NNP cord-015369-72cjogxz 4181 3 Patientin Patientin NNP cord-015369-72cjogxz 4181 4 umgehend umgehend VBP cord-015369-72cjogxz 4181 5 einer einer NNP cord-015369-72cjogxz 4181 6 chirurgischen chirurgischen NNP cord-015369-72cjogxz 4181 7 Therapie Therapie NNP cord-015369-72cjogxz 4181 8 zugeführt zugeführt NNP cord-015369-72cjogxz 4181 9 . . . cord-015369-72cjogxz 4182 1 Es Es NNP cord-015369-72cjogxz 4182 2 erfolgte erfolgte NN cord-015369-72cjogxz 4182 3 eine eine NNP cord-015369-72cjogxz 4182 4 Ablatio Ablatio NNP cord-015369-72cjogxz 4182 5 der der NNP cord-015369-72cjogxz 4182 6 betroffenen betroffenen NNP cord-015369-72cjogxz 4182 7 Brust Brust NNP cord-015369-72cjogxz 4182 8 . . . cord-015369-72cjogxz 4183 1 Etwas Etwas NNP cord-015369-72cjogxz 4183 2 aufwendiger aufwendiger NN cord-015369-72cjogxz 4183 3 gestaltet gestaltet NNP cord-015369-72cjogxz 4183 4 sich sich NNP cord-015369-72cjogxz 4183 5 der der NNP cord-015369-72cjogxz 4183 6 2 2 CD cord-015369-72cjogxz 4183 7 . . . cord-015369-72cjogxz 4184 1 Fall fall VB cord-015369-72cjogxz 4184 2 . . . cord-015369-72cjogxz 4185 1 Auch Auch NNP cord-015369-72cjogxz 4185 2 hier hier NNP cord-015369-72cjogxz 4185 3 wurde wurde VBD cord-015369-72cjogxz 4185 4 eine eine NNP cord-015369-72cjogxz 4185 5 67 67 CD cord-015369-72cjogxz 4186 1 jährige jährige NNP cord-015369-72cjogxz 4186 2 Patientin Patientin NNP cord-015369-72cjogxz 4186 3 vor vor NNP cord-015369-72cjogxz 4186 4 15 15 CD cord-015369-72cjogxz 4186 5 Jahren Jahren NNP cord-015369-72cjogxz 4186 6 wegen wegen NNP cord-015369-72cjogxz 4186 7 eines eines NNP cord-015369-72cjogxz 4186 8 invasiv invasiv NNP cord-015369-72cjogxz 4186 9 duktalen duktalen NNP cord-015369-72cjogxz 4186 10 Mammacarzinom Mammacarzinom NNP cord-015369-72cjogxz 4186 11 einer einer NNP cord-015369-72cjogxz 4186 12 brusterhaltenden brusterhaltenden NNP cord-015369-72cjogxz 4186 13 Operation Operation NNP cord-015369-72cjogxz 4186 14 mit mit NNP cord-015369-72cjogxz 4186 15 anschließender anschließender NN cord-015369-72cjogxz 4186 16 Radiatio Radiatio NNP cord-015369-72cjogxz 4186 17 unterzogen unterzogen NNP cord-015369-72cjogxz 4186 18 . . . cord-015369-72cjogxz 4187 1 Vor Vor NNP cord-015369-72cjogxz 4187 2 10 10 CD cord-015369-72cjogxz 4188 1 Monaten Monaten NNP cord-015369-72cjogxz 4188 2 kam kam NNP cord-015369-72cjogxz 4189 1 es es XX cord-015369-72cjogxz 4189 2 zum zum NNP cord-015369-72cjogxz 4189 3 Auftreten Auftreten NNP cord-015369-72cjogxz 4189 4 eines eines NNP cord-015369-72cjogxz 4189 5 Knotens Knotens NNPS cord-015369-72cjogxz 4189 6 in in IN cord-015369-72cjogxz 4189 7 der der NNP cord-015369-72cjogxz 4189 8 Axilla Axilla NNP cord-015369-72cjogxz 4189 9 der der NNP cord-015369-72cjogxz 4189 10 operierten operierten NNP cord-015369-72cjogxz 4189 11 Brust Brust NNP cord-015369-72cjogxz 4189 12 . . . cord-015369-72cjogxz 4190 1 Man man NN cord-015369-72cjogxz 4190 2 dachte dachte NNP cord-015369-72cjogxz 4190 3 primär primär VBP cord-015369-72cjogxz 4190 4 an an DT cord-015369-72cjogxz 4191 1 ein ein NNP cord-015369-72cjogxz 4191 2 Lokalrezidiv Lokalrezidiv NNP cord-015369-72cjogxz 4191 3 und und IN cord-015369-72cjogxz 4191 4 entfernte entfernte NNP cord-015369-72cjogxz 4191 5 dies die VBZ cord-015369-72cjogxz 4191 6 . . . cord-015369-72cjogxz 4192 1 Die die VB cord-015369-72cjogxz 4193 1 Histologie Histologie NNP cord-015369-72cjogxz 4193 2 ergab ergab NNP cord-015369-72cjogxz 4194 1 ein ein NNP cord-015369-72cjogxz 4194 2 malignes malignes NNP cord-015369-72cjogxz 4194 3 fibröses fibröses NNP cord-015369-72cjogxz 4194 4 Histiozytom Histiozytom NNP cord-015369-72cjogxz 4194 5 . . . cord-015369-72cjogxz 4195 1 Die die VB cord-015369-72cjogxz 4196 1 Resektion resektion NN cord-015369-72cjogxz 4196 2 erfolgte erfolgte NN cord-015369-72cjogxz 4196 3 damals damal NNS cord-015369-72cjogxz 4196 4 nicht nicht NNP cord-015369-72cjogxz 4196 5 i -PRON- PRP cord-015369-72cjogxz 4196 6 m be VBP cord-015369-72cjogxz 4196 7 Gesunden Gesunden NNP cord-015369-72cjogxz 4196 8 . . . cord-015369-72cjogxz 4197 1 Innerhalb Innerhalb NNP cord-015369-72cjogxz 4197 2 weniger weniger NNP cord-015369-72cjogxz 4197 3 Monate Monate NNP cord-015369-72cjogxz 4198 1 kam kam NNP cord-015369-72cjogxz 4198 2 es es NNP cord-015369-72cjogxz 4198 3 zu zu NNP cord-015369-72cjogxz 4198 4 einem einem NNP cord-015369-72cjogxz 4198 5 neuerlichen neuerlichen NNP cord-015369-72cjogxz 4198 6 Rezidiv Rezidiv NNP cord-015369-72cjogxz 4198 7 . . . cord-015369-72cjogxz 4199 1 Dieses Dieses NNP cord-015369-72cjogxz 4199 2 nahm nahm NNP cord-015369-72cjogxz 4199 3 nun nun NN cord-015369-72cjogxz 4199 4 die die VB cord-015369-72cjogxz 4199 5 Axilla Axilla NNP cord-015369-72cjogxz 4199 6 , , , cord-015369-72cjogxz 4199 7 den den NNP cord-015369-72cjogxz 4199 8 gesamten gesamten NNP cord-015369-72cjogxz 4199 9 M. M. NNP cord-015369-72cjogxz 4199 10 pectoralis pectoralis JJ cord-015369-72cjogxz 4199 11 sowie sowie XX cord-015369-72cjogxz 4200 1 die die VB cord-015369-72cjogxz 4201 1 Thoraxwand Thoraxwand NNP cord-015369-72cjogxz 4201 2 i -PRON- PRP cord-015369-72cjogxz 4201 3 m be VBP cord-015369-72cjogxz 4201 4 Bereich Bereich NNP cord-015369-72cjogxz 4201 5 der der NNP cord-015369-72cjogxz 4201 6 2 2 CD cord-015369-72cjogxz 4201 7 . . . cord-015369-72cjogxz 4202 1 und und IN cord-015369-72cjogxz 4202 2 3 3 CD cord-015369-72cjogxz 4202 3 . . . cord-015369-72cjogxz 4203 1 Rippe Rippe NNP cord-015369-72cjogxz 4203 2 ein ein NNP cord-015369-72cjogxz 4203 3 . . . cord-015369-72cjogxz 4204 1 Nun Nun NNP cord-015369-72cjogxz 4204 2 wurde wurde VBD cord-015369-72cjogxz 4204 3 eine eine NNP cord-015369-72cjogxz 4204 4 Resektion Resektion NNP cord-015369-72cjogxz 4204 5 unter unter NNP cord-015369-72cjogxz 4204 6 Mitnahme Mitnahme NNP cord-015369-72cjogxz 4205 1 der der NNP cord-015369-72cjogxz 4206 1 Thoraxwand Thoraxwand NNP cord-015369-72cjogxz 4206 2 durchgeführt durchgeführt NN cord-015369-72cjogxz 4206 3 sowie sowie NNP cord-015369-72cjogxz 4206 4 einer einer NNP cord-015369-72cjogxz 4206 5 Deckung Deckung NNP cord-015369-72cjogxz 4206 6 mittel mittel NNP cord-015369-72cjogxz 4206 7 myokutanen myokutanen NNP cord-015369-72cjogxz 4206 8 Lappens Lappens NNP cord-015369-72cjogxz 4206 9 . . . cord-015369-72cjogxz 4207 1 Auch Auch NNP cord-015369-72cjogxz 4207 2 wenn wenn NNP cord-015369-72cjogxz 4208 1 diese diese NNP cord-015369-72cjogxz 4208 2 Fälle Fälle NNP cord-015369-72cjogxz 4208 3 selten selten NNP cord-015369-72cjogxz 4209 1 sind sind UH cord-015369-72cjogxz 4209 2 , , , cord-015369-72cjogxz 4209 3 so so RB cord-015369-72cjogxz 4210 1 zeigen zeigen NNP cord-015369-72cjogxz 4210 2 sie sie NNP cord-015369-72cjogxz 4210 3 doch doch NNP cord-015369-72cjogxz 4210 4 die die VB cord-015369-72cjogxz 4210 5 Aggressivität Aggressivität NNP cord-015369-72cjogxz 4210 6 dieser dieser NNP cord-015369-72cjogxz 4210 7 Tumorentitäten Tumorentitäten NNP cord-015369-72cjogxz 4210 8 . . . cord-015369-72cjogxz 4211 1 Daher Daher NNP cord-015369-72cjogxz 4211 2 muss muss VB cord-015369-72cjogxz 4211 3 unsere unsere NNP cord-015369-72cjogxz 4211 4 Sensibilität Sensibilität NNP cord-015369-72cjogxz 4211 5 dafür dafür NNP cord-015369-72cjogxz 4211 6 feinfühliger feinfühliger NNP cord-015369-72cjogxz 4212 1 werden werden NNP cord-015369-72cjogxz 4212 2 , , , cord-015369-72cjogxz 4213 1 um um UH cord-015369-72cjogxz 4213 2 früher früher NNP cord-015369-72cjogxz 4213 3 zu zu NNP cord-015369-72cjogxz 4213 4 diagnostizieren diagnostizieren NNP cord-015369-72cjogxz 4213 5 und und XX cord-015369-72cjogxz 4214 1 rasch rasch NNP cord-015369-72cjogxz 4214 2 radikal radikal NNP cord-015369-72cjogxz 4214 3 chirurgisch chirurgisch NNP cord-015369-72cjogxz 4214 4 versorgen versorgen NNP cord-015369-72cjogxz 4214 5 zu zu NNP cord-015369-72cjogxz 4214 6 können können NNP cord-015369-72cjogxz 4214 7 . . . cord-015369-72cjogxz 4215 1 Darin Darin NNP cord-015369-72cjogxz 4215 2 ist ist NN cord-015369-72cjogxz 4215 3 die die VBP cord-015369-72cjogxz 4215 4 größte größte NN cord-015369-72cjogxz 4215 5 Chance chance NN cord-015369-72cjogxz 4215 6 zum zum NNP cord-015369-72cjogxz 4215 7 Ü ü NN cord-015369-72cjogxz 4215 8 berleben berleben NN cord-015369-72cjogxz 4215 9 zu zu NNP cord-015369-72cjogxz 4215 10 sehen sehen NNP cord-015369-72cjogxz 4215 11 . . . cord-015369-72cjogxz 4216 1 Background background NN cord-015369-72cjogxz 4216 2 . . . cord-015369-72cjogxz 4217 1 After after IN cord-015369-72cjogxz 4217 2 aortic aortic JJ cord-015369-72cjogxz 4217 3 valve valve NN cord-015369-72cjogxz 4217 4 replacement replacement NN cord-015369-72cjogxz 4217 5 using use VBG cord-015369-72cjogxz 4217 6 a a DT cord-015369-72cjogxz 4217 7 tissue tissue NN cord-015369-72cjogxz 4217 8 valve valve NN cord-015369-72cjogxz 4217 9 , , , cord-015369-72cjogxz 4217 10 patients patient NNS cord-015369-72cjogxz 4217 11 are be VBP cord-015369-72cjogxz 4217 12 treated treat VBN cord-015369-72cjogxz 4217 13 with with IN cord-015369-72cjogxz 4217 14 coumadin coumadin NN cord-015369-72cjogxz 4217 15 for for IN cord-015369-72cjogxz 4217 16 3 3 CD cord-015369-72cjogxz 4217 17 months month NNS cord-015369-72cjogxz 4217 18 . . . cord-015369-72cjogxz 4218 1 If if IN cord-015369-72cjogxz 4218 2 sinus sinus NN cord-015369-72cjogxz 4218 3 rhythm rhythm NN cord-015369-72cjogxz 4218 4 is be VBZ cord-015369-72cjogxz 4218 5 evident evident JJ cord-015369-72cjogxz 4218 6 , , , cord-015369-72cjogxz 4218 7 therapy therapy NN cord-015369-72cjogxz 4218 8 is be VBZ cord-015369-72cjogxz 4218 9 changed change VBN cord-015369-72cjogxz 4218 10 to to IN cord-015369-72cjogxz 4218 11 100 100 CD cord-015369-72cjogxz 4218 12 mg mg NNS cord-015369-72cjogxz 4218 13 of of IN cord-015369-72cjogxz 4218 14 aspirin aspirin NN cord-015369-72cjogxz 4218 15 a a DT cord-015369-72cjogxz 4218 16 day day NN cord-015369-72cjogxz 4218 17 . . . cord-015369-72cjogxz 4219 1 These these DT cord-015369-72cjogxz 4219 2 are be VBP cord-015369-72cjogxz 4219 3 STS STS NNP cord-015369-72cjogxz 4219 4 , , , cord-015369-72cjogxz 4219 5 ACC ACC NNP cord-015369-72cjogxz 4219 6 / / SYM cord-015369-72cjogxz 4219 7 AHA AHA NNP cord-015369-72cjogxz 4219 8 and and CC cord-015369-72cjogxz 4219 9 ESC ESC NNP cord-015369-72cjogxz 4219 10 guidelines guideline NNS cord-015369-72cjogxz 4219 11 . . . cord-015369-72cjogxz 4220 1 Clopridigel Clopridigel NNP cord-015369-72cjogxz 4220 2 is be VBZ cord-015369-72cjogxz 4220 3 well well RB cord-015369-72cjogxz 4220 4 known know VBN cord-015369-72cjogxz 4220 5 in in IN cord-015369-72cjogxz 4220 6 cardiology cardiology NN cord-015369-72cjogxz 4220 7 after after IN cord-015369-72cjogxz 4220 8 coronary coronary JJ cord-015369-72cjogxz 4220 9 stenting stenting NN cord-015369-72cjogxz 4220 10 and and CC cord-015369-72cjogxz 4220 11 also also RB cord-015369-72cjogxz 4220 12 in in IN cord-015369-72cjogxz 4220 13 peripheral peripheral JJ cord-015369-72cjogxz 4220 14 vascular vascular JJ cord-015369-72cjogxz 4220 15 surgery surgery NN cord-015369-72cjogxz 4220 16 . . . cord-015369-72cjogxz 4221 1 Methods method NNS cord-015369-72cjogxz 4221 2 . . . cord-015369-72cjogxz 4222 1 In in IN cord-015369-72cjogxz 4222 2 our -PRON- PRP$ cord-015369-72cjogxz 4222 3 2-year 2-year CD cord-015369-72cjogxz 4222 4 retrospective retrospective JJ cord-015369-72cjogxz 4222 5 analysis analysis NN cord-015369-72cjogxz 4222 6 130 130 CD cord-015369-72cjogxz 4222 7 patients patient NNS cord-015369-72cjogxz 4222 8 were be VBD cord-015369-72cjogxz 4222 9 treated treat VBN cord-015369-72cjogxz 4222 10 with with IN cord-015369-72cjogxz 4222 11 clopridogel clopridogel NN cord-015369-72cjogxz 4222 12 after after IN cord-015369-72cjogxz 4222 13 biological biological JJ cord-015369-72cjogxz 4222 14 valve valve NN cord-015369-72cjogxz 4222 15 replacement replacement NN cord-015369-72cjogxz 4222 16 ( ( -LRB- cord-015369-72cjogxz 4222 17 BAVR BAVR NNP cord-015369-72cjogxz 4222 18 ) ) -RRB- cord-015369-72cjogxz 4222 19 . . . cord-015369-72cjogxz 4223 1 The the DT cord-015369-72cjogxz 4223 2 therapy therapy NN cord-015369-72cjogxz 4223 3 started start VBD cord-015369-72cjogxz 4223 4 on on IN cord-015369-72cjogxz 4223 5 the the DT cord-015369-72cjogxz 4223 6 fifth fifth JJ cord-015369-72cjogxz 4223 7 day day NN cord-015369-72cjogxz 4223 8 after after IN cord-015369-72cjogxz 4223 9 surgery surgery NN cord-015369-72cjogxz 4223 10 and and CC cord-015369-72cjogxz 4223 11 ended end VBD cord-015369-72cjogxz 4223 12 after after IN cord-015369-72cjogxz 4223 13 3 3 CD cord-015369-72cjogxz 4223 14 months month NNS cord-015369-72cjogxz 4223 15 . . . cord-015369-72cjogxz 4224 1 In in IN cord-015369-72cjogxz 4224 2 our -PRON- PRP$ cord-015369-72cjogxz 4224 3 group group NN cord-015369-72cjogxz 4224 4 we -PRON- PRP cord-015369-72cjogxz 4224 5 had have VBD cord-015369-72cjogxz 4224 6 also also RB cord-015369-72cjogxz 4224 7 patients patient NNS cord-015369-72cjogxz 4224 8 with with IN cord-015369-72cjogxz 4224 9 combined combine VBN cord-015369-72cjogxz 4224 10 surgery surgery NN cord-015369-72cjogxz 4224 11 like like IN cord-015369-72cjogxz 4224 12 valve valve NN cord-015369-72cjogxz 4224 13 replacement replacement NN cord-015369-72cjogxz 4224 14 plus plus CC cord-015369-72cjogxz 4224 15 CABG CABG NNP cord-015369-72cjogxz 4224 16 or or CC cord-015369-72cjogxz 4224 17 carotid carotid JJ cord-015369-72cjogxz 4224 18 surgery surgery NN cord-015369-72cjogxz 4224 19 . . . cord-015369-72cjogxz 4225 1 All all DT cord-015369-72cjogxz 4225 2 patients patient NNS cord-015369-72cjogxz 4225 3 underwent undergo VBD cord-015369-72cjogxz 4225 4 echocardiography echocardiography NN cord-015369-72cjogxz 4225 5 before before IN cord-015369-72cjogxz 4225 6 dismission dismission NN cord-015369-72cjogxz 4225 7 and and CC cord-015369-72cjogxz 4225 8 after after IN cord-015369-72cjogxz 4225 9 3 3 CD cord-015369-72cjogxz 4225 10 months month NNS cord-015369-72cjogxz 4225 11 . . . cord-015369-72cjogxz 4226 1 Results result NNS cord-015369-72cjogxz 4226 2 . . . cord-015369-72cjogxz 4227 1 In in IN cord-015369-72cjogxz 4227 2 our -PRON- PRP$ cord-015369-72cjogxz 4227 3 study study NN cord-015369-72cjogxz 4227 4 group group NN cord-015369-72cjogxz 4227 5 we -PRON- PRP cord-015369-72cjogxz 4227 6 could could MD cord-015369-72cjogxz 4227 7 not not RB cord-015369-72cjogxz 4227 8 detect detect VB cord-015369-72cjogxz 4227 9 any any DT cord-015369-72cjogxz 4227 10 signs sign NNS cord-015369-72cjogxz 4227 11 of of IN cord-015369-72cjogxz 4227 12 thrombembolic thrombembolic JJ cord-015369-72cjogxz 4227 13 complications complication NNS cord-015369-72cjogxz 4227 14 or or CC cord-015369-72cjogxz 4227 15 neurological neurological JJ cord-015369-72cjogxz 4227 16 disorders disorder NNS cord-015369-72cjogxz 4227 17 . . . cord-015369-72cjogxz 4228 1 We -PRON- PRP cord-015369-72cjogxz 4228 2 found find VBD cord-015369-72cjogxz 4228 3 regular regular JJ cord-015369-72cjogxz 4228 4 function function NN cord-015369-72cjogxz 4228 5 of of IN cord-015369-72cjogxz 4228 6 the the DT cord-015369-72cjogxz 4228 7 valve valve NN cord-015369-72cjogxz 4228 8 prosthesis prosthesis NN cord-015369-72cjogxz 4228 9 in in IN cord-015369-72cjogxz 4228 10 all all DT cord-015369-72cjogxz 4228 11 cases case NNS cord-015369-72cjogxz 4228 12 . . . cord-015369-72cjogxz 4229 1 One one CD cord-015369-72cjogxz 4229 2 patient patient NN cord-015369-72cjogxz 4229 3 had have VBD cord-015369-72cjogxz 4229 4 to to TO cord-015369-72cjogxz 4229 5 be be VB cord-015369-72cjogxz 4229 6 re re VBN cord-015369-72cjogxz 4229 7 - - VBN cord-015369-72cjogxz 4229 8 operated operate VBN cord-015369-72cjogxz 4229 9 cause cause NN cord-015369-72cjogxz 4229 10 of of IN cord-015369-72cjogxz 4229 11 endocarditis endocarditis NN cord-015369-72cjogxz 4229 12 of of IN cord-015369-72cjogxz 4229 13 the the DT cord-015369-72cjogxz 4229 14 prosthesis prosthesis NN cord-015369-72cjogxz 4229 15 and and CC cord-015369-72cjogxz 4229 16 died die VBD cord-015369-72cjogxz 4229 17 after after IN cord-015369-72cjogxz 4229 18 prolonged prolong VBN cord-015369-72cjogxz 4229 19 ventilation ventilation NN cord-015369-72cjogxz 4229 20 problems problem NNS cord-015369-72cjogxz 4229 21 . . . cord-015369-72cjogxz 4230 1 In in IN cord-015369-72cjogxz 4230 2 the the DT cord-015369-72cjogxz 4230 3 control control NN cord-015369-72cjogxz 4230 4 group group NN cord-015369-72cjogxz 4230 5 ( ( -LRB- cord-015369-72cjogxz 4230 6 230 230 CD cord-015369-72cjogxz 4230 7 patients patient NNS cord-015369-72cjogxz 4230 8 ) ) -RRB- cord-015369-72cjogxz 4230 9 we -PRON- PRP cord-015369-72cjogxz 4230 10 found find VBD cord-015369-72cjogxz 4230 11 to to IN cord-015369-72cjogxz 4230 12 cases case NNS cord-015369-72cjogxz 4230 13 of of IN cord-015369-72cjogxz 4230 14 intracerebral intracerebral NNP cord-015369-72cjogxz 4230 15 haemorrhagia haemorrhagia NNP cord-015369-72cjogxz 4230 16 , , , cord-015369-72cjogxz 4230 17 which which WDT cord-015369-72cjogxz 4230 18 caused cause VBD cord-015369-72cjogxz 4230 19 to to IN cord-015369-72cjogxz 4230 20 death death NN cord-015369-72cjogxz 4230 21 . . . cord-015369-72cjogxz 4231 1 Both both DT cord-015369-72cjogxz 4231 2 of of IN cord-015369-72cjogxz 4231 3 them -PRON- PRP cord-015369-72cjogxz 4231 4 were be VBD cord-015369-72cjogxz 4231 5 older old JJR cord-015369-72cjogxz 4231 6 then then RB cord-015369-72cjogxz 4231 7 80 80 CD cord-015369-72cjogxz 4231 8 years year NNS cord-015369-72cjogxz 4231 9 . . . cord-015369-72cjogxz 4232 1 Conclusions conclusion NNS cord-015369-72cjogxz 4232 2 . . . cord-015369-72cjogxz 4233 1 In in IN cord-015369-72cjogxz 4233 2 the the DT cord-015369-72cjogxz 4233 3 last last JJ cord-015369-72cjogxz 4233 4 years year NNS cord-015369-72cjogxz 4233 5 the the DT cord-015369-72cjogxz 4233 6 clinical clinical JJ cord-015369-72cjogxz 4233 7 use use NN cord-015369-72cjogxz 4233 8 of of IN cord-015369-72cjogxz 4233 9 tissue tissue NN cord-015369-72cjogxz 4233 10 valves valve NNS cord-015369-72cjogxz 4233 11 has have VBZ cord-015369-72cjogxz 4233 12 increased increase VBN cord-015369-72cjogxz 4233 13 because because IN cord-015369-72cjogxz 4233 14 of of IN cord-015369-72cjogxz 4233 15 longer long JJR cord-015369-72cjogxz 4233 16 durability durability NN cord-015369-72cjogxz 4233 17 . . . cord-015369-72cjogxz 4234 1 Many many JJ cord-015369-72cjogxz 4234 2 post post JJ cord-015369-72cjogxz 4234 3 - - JJ cord-015369-72cjogxz 4234 4 operative operative JJ cord-015369-72cjogxz 4234 5 regimes regime NNS cord-015369-72cjogxz 4234 6 have have VBP cord-015369-72cjogxz 4234 7 been be VBN cord-015369-72cjogxz 4234 8 described describe VBN cord-015369-72cjogxz 4234 9 . . . cord-015369-72cjogxz 4235 1 Clopridogel Clopridogel NNP cord-015369-72cjogxz 4235 2 75 75 CD cord-015369-72cjogxz 4235 3 mg mg NNS cord-015369-72cjogxz 4235 4 a a DT cord-015369-72cjogxz 4235 5 day day NN cord-015369-72cjogxz 4235 6 is be VBZ cord-015369-72cjogxz 4235 7 an an DT cord-015369-72cjogxz 4235 8 excellent excellent JJ cord-015369-72cjogxz 4235 9 alternative alternative JJ cord-015369-72cjogxz 4235 10 therapy therapy NN cord-015369-72cjogxz 4235 11 after after IN cord-015369-72cjogxz 4235 12 bilogical bilogical JJ cord-015369-72cjogxz 4235 13 valve valve NN cord-015369-72cjogxz 4235 14 replacement replacement NN cord-015369-72cjogxz 4235 15 . . . cord-015369-72cjogxz 4236 1 We -PRON- PRP cord-015369-72cjogxz 4236 2 all all DT cord-015369-72cjogxz 4236 3 know know VBP cord-015369-72cjogxz 4236 4 the the DT cord-015369-72cjogxz 4236 5 compliance compliance NN cord-015369-72cjogxz 4236 6 of of IN cord-015369-72cjogxz 4236 7 elder eld JJR cord-015369-72cjogxz 4236 8 patients patient NNS cord-015369-72cjogxz 4236 9 after after IN cord-015369-72cjogxz 4236 10 cardiac cardiac JJ cord-015369-72cjogxz 4236 11 surgery surgery NN cord-015369-72cjogxz 4236 12 . . . cord-015369-72cjogxz 4237 1 So so RB cord-015369-72cjogxz 4237 2 we -PRON- PRP cord-015369-72cjogxz 4237 3 have have VBP cord-015369-72cjogxz 4237 4 an an DT cord-015369-72cjogxz 4237 5 easy easy JJ cord-015369-72cjogxz 4237 6 treatment treatment NN cord-015369-72cjogxz 4237 7 for for IN cord-015369-72cjogxz 4237 8 this this DT cord-015369-72cjogxz 4237 9 group group NN cord-015369-72cjogxz 4237 10 of of IN cord-015369-72cjogxz 4237 11 patients patient NNS cord-015369-72cjogxz 4237 12 . . . cord-015369-72cjogxz 4238 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4238 2 . . . cord-015369-72cjogxz 4239 1 Die die VB cord-015369-72cjogxz 4239 2 Zunahme Zunahme NNP cord-015369-72cjogxz 4239 3 des des FW cord-015369-72cjogxz 4239 4 perkutanen perkutanen NN cord-015369-72cjogxz 4239 5 Aortenklappenersatzes Aortenklappenersatzes NNP cord-015369-72cjogxz 4239 6 , , , cord-015369-72cjogxz 4239 7 berechtigt berechtigt NNP cord-015369-72cjogxz 4239 8 die die VB cord-015369-72cjogxz 4240 1 Notwendigkeit Notwendigkeit NNP cord-015369-72cjogxz 4240 2 zur zur NNP cord-015369-72cjogxz 4240 3 Evaluation Evaluation NNP cord-015369-72cjogxz 4240 4 der der NNP cord-015369-72cjogxz 4240 5 Ü Ü NNP cord-015369-72cjogxz 4240 6 berlebensrate berlebensrate NN cord-015369-72cjogxz 4240 7 nach nach NNP cord-015369-72cjogxz 4240 8 operativem operativem NNP cord-015369-72cjogxz 4240 9 biologischen biologischen NNP cord-015369-72cjogxz 4240 10 Aortenklappenersatz Aortenklappenersatz NNP cord-015369-72cjogxz 4240 11 mit mit NNP cord-015369-72cjogxz 4240 12 und und XX cord-015369-72cjogxz 4241 1 ohne ohne NNP cord-015369-72cjogxz 4241 2 zusätzlichen zusätzlichen NNP cord-015369-72cjogxz 4242 1 aortokoronaren aortokoronaren NNP cord-015369-72cjogxz 4242 2 Bypass Bypass NNP cord-015369-72cjogxz 4242 3 bei bei NNP cord-015369-72cjogxz 4242 4 Patienten Patienten NNP cord-015369-72cjogxz 4242 5 ! ! . cord-015369-72cjogxz 4243 1 80 80 CD cord-015369-72cjogxz 4243 2 Jahren Jahren NNP cord-015369-72cjogxz 4243 3 . . . cord-015369-72cjogxz 4244 1 In in IN cord-015369-72cjogxz 4244 2 dieser dieser NNP cord-015369-72cjogxz 4244 3 Studie Studie NNP cord-015369-72cjogxz 4244 4 wurden wurden NNP cord-015369-72cjogxz 4244 5 Risikofaktoren Risikofaktoren NNP cord-015369-72cjogxz 4244 6 , , , cord-015369-72cjogxz 4244 7 die die VB cord-015369-72cjogxz 4245 1 die die VB cord-015369-72cjogxz 4245 2 1-Jahres 1-Jahres NNP cord-015369-72cjogxz 4245 3 Mortalität Mortalität NNP cord-015369-72cjogxz 4245 4 beeinflussen beeinflussen NN cord-015369-72cjogxz 4245 5 , , , cord-015369-72cjogxz 4245 6 untersucht untersucht NNP cord-015369-72cjogxz 4245 7 . . . cord-015369-72cjogxz 4246 1 Methodik Methodik NNP cord-015369-72cjogxz 4246 2 . . . cord-015369-72cjogxz 4247 1 Retrospektiv retrospektiv RB cord-015369-72cjogxz 4247 2 wurden wurden XX cord-015369-72cjogxz 4248 1 i -PRON- PRP cord-015369-72cjogxz 4248 2 m be VBP cord-015369-72cjogxz 4248 3 Zeitraum Zeitraum NNP cord-015369-72cjogxz 4248 4 von von NNP cord-015369-72cjogxz 4248 5 Jänner Jänner NNP cord-015369-72cjogxz 4248 6 2005 2005 CD cord-015369-72cjogxz 4249 1 bis bis NNP cord-015369-72cjogxz 4249 2 Dezember Dezember NNP cord-015369-72cjogxz 4249 3 2007 2007 CD cord-015369-72cjogxz 4249 4 einhundertvierundfü einhundertvierundfü NNP cord-015369-72cjogxz 4249 5 nfzig nfzig NNP cord-015369-72cjogxz 4250 1 Patienten Patienten NNP cord-015369-72cjogxz 4250 2 ( ( -LRB- cord-015369-72cjogxz 4250 3 102 102 CD cord-015369-72cjogxz 4250 4 w w NN cord-015369-72cjogxz 4250 5 , , , cord-015369-72cjogxz 4250 6 52 52 CD cord-015369-72cjogxz 4250 7 m m NNP cord-015369-72cjogxz 4250 8 ) ) -RRB- cord-015369-72cjogxz 4250 9 mit mit NNP cord-015369-72cjogxz 4250 10 einem einem NNP cord-015369-72cjogxz 4250 11 medianen medianen NNP cord-015369-72cjogxz 4250 12 Alter Alter NNP cord-015369-72cjogxz 4251 1 von von NNP cord-015369-72cjogxz 4251 2 82,9 82,9 CD cord-015369-72cjogxz 4251 3 AE AE NNP cord-015369-72cjogxz 4252 1 2,5 2,5 CD cord-015369-72cjogxz 4252 2 Jahren Jahren NNP cord-015369-72cjogxz 4252 3 ( ( -LRB- cord-015369-72cjogxz 4252 4 80 80 CD cord-015369-72cjogxz 4252 5 - - SYM cord-015369-72cjogxz 4252 6 92 92 CD cord-015369-72cjogxz 4252 7 Jahre Jahre NNP cord-015369-72cjogxz 4252 8 ) ) -RRB- cord-015369-72cjogxz 4252 9 , , . cord-015369-72cjogxz 4253 1 einen einen NNP cord-015369-72cjogxz 4253 2 biologischen biologischen NNP cord-015369-72cjogxz 4253 3 Aortenklappenersatz Aortenklappenersatz NNP cord-015369-72cjogxz 4253 4 mit mit NNP cord-015369-72cjogxz 4253 5 ( ( -LRB- cord-015369-72cjogxz 4253 6 n n NN cord-015369-72cjogxz 4253 7 ¼ ¼ NNP cord-015369-72cjogxz 4253 8 80 80 CD cord-015369-72cjogxz 4253 9 ) ) -RRB- cord-015369-72cjogxz 4254 1 oder oder NNP cord-015369-72cjogxz 4254 2 ohne ohne NNP cord-015369-72cjogxz 4254 3 ( ( -LRB- cord-015369-72cjogxz 4254 4 n n NNP cord-015369-72cjogxz 4254 5 ¼ ¼ NNP cord-015369-72cjogxz 4254 6 74 74 CD cord-015369-72cjogxz 4254 7 ) ) -RRB- cord-015369-72cjogxz 4254 8 aortokoronaren aortokoronaren NNP cord-015369-72cjogxz 4255 1 Bypass Bypass NNP cord-015369-72cjogxz 4255 2 unterzogen unterzogen NNP cord-015369-72cjogxz 4255 3 . . . cord-015369-72cjogxz 4256 1 Mittels Mittels NNP cord-015369-72cjogxz 4256 2 Chi Chi NNP cord-015369-72cjogxz 4256 3 - - HYPH cord-015369-72cjogxz 4256 4 square square NNP cord-015369-72cjogxz 4256 5 Test Test NNP cord-015369-72cjogxz 4256 6 und und RB cord-015369-72cjogxz 4257 1 Mann Mann NNP cord-015369-72cjogxz 4257 2 - - HYPH cord-015369-72cjogxz 4257 3 Whitney Whitney NNP cord-015369-72cjogxz 4257 4 Test Test NNP cord-015369-72cjogxz 4257 5 wurden wurden NNS cord-015369-72cjogxz 4257 6 die die VBP cord-015369-72cjogxz 4257 7 Einflussfaktoren Einflussfaktoren NNP cord-015369-72cjogxz 4257 8 auf auf NNP cord-015369-72cjogxz 4257 9 die die VBP cord-015369-72cjogxz 4257 10 Ü ü NN cord-015369-72cjogxz 4257 11 berlebensrate berlebensrate NN cord-015369-72cjogxz 4257 12 untersucht untersucht NNP cord-015369-72cjogxz 4257 13 . . . cord-015369-72cjogxz 4258 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4258 2 . . . cord-015369-72cjogxz 4259 1 Das Das NNP cord-015369-72cjogxz 4259 2 1-Jahres 1-Jahres NNP cord-015369-72cjogxz 4259 3 Follow Follow NNP cord-015369-72cjogxz 4259 4 - - HYPH cord-015369-72cjogxz 4259 5 up up NN cord-015369-72cjogxz 4259 6 zeigte zeigte NNP cord-015369-72cjogxz 4259 7 eine eine NNP cord-015369-72cjogxz 4259 8 Ü Ü NNP cord-015369-72cjogxz 4259 9 berlebensrate berlebensrate NN cord-015369-72cjogxz 4259 10 von von NNP cord-015369-72cjogxz 4259 11 81,8 81,8 CD cord-015369-72cjogxz 4259 12 % % NN cord-015369-72cjogxz 4259 13 . . . cord-015369-72cjogxz 4260 1 Nach Nach NNP cord-015369-72cjogxz 4260 2 isoliertem isoliertem NNP cord-015369-72cjogxz 4261 1 Aortenklappenersatz aortenklappenersatz RB cord-015369-72cjogxz 4261 2 sind sind NNP cord-015369-72cjogxz 4262 1 12 12 CD cord-015369-72cjogxz 4262 2 Patienten Patienten NNP cord-015369-72cjogxz 4262 3 ( ( -LRB- cord-015369-72cjogxz 4262 4 7,8 7,8 CD cord-015369-72cjogxz 4262 5 % % NN cord-015369-72cjogxz 4262 6 ) ) -RRB- cord-015369-72cjogxz 4262 7 und und RB cord-015369-72cjogxz 4263 1 nach nach NNP cord-015369-72cjogxz 4263 2 einem einem NNP cord-015369-72cjogxz 4263 3 Kombinationseingriff Kombinationseingriff NNP cord-015369-72cjogxz 4263 4 mit mit NNP cord-015369-72cjogxz 4263 5 koronarem koronarem NNP cord-015369-72cjogxz 4263 6 Bypass Bypass NNP cord-015369-72cjogxz 4264 1 16 16 CD cord-015369-72cjogxz 4264 2 Patienten Patienten NNP cord-015369-72cjogxz 4264 3 ( ( -LRB- cord-015369-72cjogxz 4264 4 10,4 10,4 CD cord-015369-72cjogxz 4264 5 % % NN cord-015369-72cjogxz 4264 6 ) ) -RRB- cord-015369-72cjogxz 4264 7 verstorben verstorben NN cord-015369-72cjogxz 4264 8 . . . cord-015369-72cjogxz 4265 1 Die die VB cord-015369-72cjogxz 4265 2 präoperativen präoperativen NNP cord-015369-72cjogxz 4265 3 Risikofaktoren Risikofaktoren NNP cord-015369-72cjogxz 4265 4 in in IN cord-015369-72cjogxz 4265 5 Bezug Bezug NNP cord-015369-72cjogxz 4266 1 auf auf NNP cord-015369-72cjogxz 4266 2 die die VBP cord-015369-72cjogxz 4266 3 Mortalität Mortalität NNP cord-015369-72cjogxz 4266 4 , , , cord-015369-72cjogxz 4266 5 wie wie VB cord-015369-72cjogxz 4266 6 renale renale JJ cord-015369-72cjogxz 4266 7 Insuffizienz Insuffizienz NNP cord-015369-72cjogxz 4266 8 ( ( -LRB- cord-015369-72cjogxz 4267 1 38,1 38,1 CD cord-015369-72cjogxz 4267 2 % % NN cord-015369-72cjogxz 4267 3 vs. vs. CC cord-015369-72cjogxz 4267 4 39,3 39,3 CD cord-015369-72cjogxz 4267 5 % % NN cord-015369-72cjogxz 4267 6 , , , cord-015369-72cjogxz 4267 7 p p NN cord-015369-72cjogxz 4267 8 ¼ ¼ NN cord-015369-72cjogxz 4267 9 0,44 0,44 CD cord-015369-72cjogxz 4267 10 ) ) -RRB- cord-015369-72cjogxz 4267 11 , , , cord-015369-72cjogxz 4267 12 COPD COPD NNP cord-015369-72cjogxz 4267 13 ( ( -LRB- cord-015369-72cjogxz 4267 14 49,2 49,2 CD cord-015369-72cjogxz 4267 15 % % NN cord-015369-72cjogxz 4267 16 vs. vs. IN cord-015369-72cjogxz 4267 17 60,7 60,7 CD cord-015369-72cjogxz 4267 18 % % NN cord-015369-72cjogxz 4267 19 , , , cord-015369-72cjogxz 4267 20 p p NN cord-015369-72cjogxz 4267 21 ¼ ¼ NN cord-015369-72cjogxz 4267 22 0,45 0,45 NNP cord-015369-72cjogxz 4267 23 ) ) -RRB- cord-015369-72cjogxz 4267 24 , , , cord-015369-72cjogxz 4267 25 Diabetes diabetes NN cord-015369-72cjogxz 4267 26 mellitus mellitus NN cord-015369-72cjogxz 4267 27 II II NNP cord-015369-72cjogxz 4267 28 ( ( -LRB- cord-015369-72cjogxz 4267 29 27,8 27,8 CD cord-015369-72cjogxz 4267 30 % % NN cord-015369-72cjogxz 4267 31 vs. vs. IN cord-015369-72cjogxz 4267 32 32,1 32,1 CD cord-015369-72cjogxz 4267 33 % % NN cord-015369-72cjogxz 4267 34 , , , cord-015369-72cjogxz 4267 35 p p NN cord-015369-72cjogxz 4267 36 ¼ ¼ CD cord-015369-72cjogxz 4267 37 0,82 0,82 CD cord-015369-72cjogxz 4267 38 ) ) -RRB- cord-015369-72cjogxz 4267 39 , , , cord-015369-72cjogxz 4267 40 CAVK CAVK NNP cord-015369-72cjogxz 4267 41 ( ( -LRB- cord-015369-72cjogxz 4267 42 15,9 15,9 CD cord-015369-72cjogxz 4267 43 % % NN cord-015369-72cjogxz 4267 44 vs. vs. IN cord-015369-72cjogxz 4267 45 14,3 14,3 CD cord-015369-72cjogxz 4267 46 % % NN cord-015369-72cjogxz 4267 47 , , , cord-015369-72cjogxz 4267 48 p p NN cord-015369-72cjogxz 4267 49 ¼ ¼ NNP cord-015369-72cjogxz 4267 50 0,94 0,94 NNP cord-015369-72cjogxz 4267 51 ) ) -RRB- cord-015369-72cjogxz 4267 52 , , , cord-015369-72cjogxz 4267 53 pAVK pAVK NNP cord-015369-72cjogxz 4267 54 ( ( -LRB- cord-015369-72cjogxz 4267 55 7,9 7,9 CD cord-015369-72cjogxz 4267 56 % % NN cord-015369-72cjogxz 4267 57 vs. vs. IN cord-015369-72cjogxz 4267 58 21,4 21,4 CD cord-015369-72cjogxz 4267 59 % % NN cord-015369-72cjogxz 4267 60 , , , cord-015369-72cjogxz 4267 61 p p NN cord-015369-72cjogxz 4267 62 ¼ ¼ NNP cord-015369-72cjogxz 4267 63 0,07 0,07 CD cord-015369-72cjogxz 4267 64 ) ) -RRB- cord-015369-72cjogxz 4267 65 , , , cord-015369-72cjogxz 4267 66 logistischer logistischer NNP cord-015369-72cjogxz 4267 67 EURO EURO NNP cord-015369-72cjogxz 4267 68 Score Score NNP cord-015369-72cjogxz 4267 69 ( ( -LRB- cord-015369-72cjogxz 4267 70 median median JJ cord-015369-72cjogxz 4267 71 12,3 12,3 CD cord-015369-72cjogxz 4267 72 vs. vs. CC cord-015369-72cjogxz 4267 73 13,0 13,0 CD cord-015369-72cjogxz 4267 74 , , , cord-015369-72cjogxz 4267 75 p p NN cord-015369-72cjogxz 4267 76 ¼ ¼ CD cord-015369-72cjogxz 4267 77 0,64 0,64 CD cord-015369-72cjogxz 4267 78 ) ) -RRB- cord-015369-72cjogxz 4267 79 und und IN cord-015369-72cjogxz 4267 80 Kombinationseingriff Kombinationseingriff NNP cord-015369-72cjogxz 4267 81 ( ( -LRB- cord-015369-72cjogxz 4267 82 50,8 50,8 CD cord-015369-72cjogxz 4267 83 % % NN cord-015369-72cjogxz 4267 84 vs. vs. IN cord-015369-72cjogxz 4267 85 57,1 57,1 CD cord-015369-72cjogxz 4267 86 % % NN cord-015369-72cjogxz 4267 87 , , , cord-015369-72cjogxz 4267 88 p p NN cord-015369-72cjogxz 4267 89 ¼ ¼ CD cord-015369-72cjogxz 4267 90 0,69 0,69 NNP cord-015369-72cjogxz 4267 91 ) ) -RRB- cord-015369-72cjogxz 4267 92 wurden wurden VBD cord-015369-72cjogxz 4267 93 evaluiert evaluiert NNP cord-015369-72cjogxz 4267 94 . . . cord-015369-72cjogxz 4268 1 Die die VB cord-015369-72cjogxz 4269 1 einzelnen einzelnen NNP cord-015369-72cjogxz 4269 2 Risikofaktoren Risikofaktoren NNP cord-015369-72cjogxz 4269 3 zeigten zeigten NNP cord-015369-72cjogxz 4269 4 keinen keinen NNP cord-015369-72cjogxz 4269 5 signifikanten signifikanten NNP cord-015369-72cjogxz 4269 6 Einfluss Einfluss NNP cord-015369-72cjogxz 4269 7 auf auf NNP cord-015369-72cjogxz 4269 8 die die VBP cord-015369-72cjogxz 4269 9 Mortalitätsrate Mortalitätsrate NNP cord-015369-72cjogxz 4269 10 bei bei NNP cord-015369-72cjogxz 4269 11 Patienten Patienten NNP cord-015369-72cjogxz 4269 12 ! ! . cord-015369-72cjogxz 4270 1 80 80 CD cord-015369-72cjogxz 4270 2 Jahren Jahren NNP cord-015369-72cjogxz 4270 3 . . . cord-015369-72cjogxz 4271 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4271 2 . . . cord-015369-72cjogxz 4272 1 Die die VB cord-015369-72cjogxz 4272 2 vorliegenden vorliegenden JJ cord-015369-72cjogxz 4272 3 Daten Daten NNP cord-015369-72cjogxz 4273 1 zeigen zeigen NNP cord-015369-72cjogxz 4273 2 gute gute NNP cord-015369-72cjogxz 4273 3 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4273 4 der der NNP cord-015369-72cjogxz 4273 5 Ü Ü NNP cord-015369-72cjogxz 4273 6 berlebensraten berlebensraten NNP cord-015369-72cjogxz 4274 1 nach nach NNP cord-015369-72cjogxz 4274 2 operativem operativem NNP cord-015369-72cjogxz 4274 3 Aortenklappenersatz Aortenklappenersatz NNP cord-015369-72cjogxz 4274 4 bei bei NNP cord-015369-72cjogxz 4274 5 Patienten Patienten NNP cord-015369-72cjogxz 4275 1 über über NNP cord-015369-72cjogxz 4276 1 80 80 CD cord-015369-72cjogxz 4276 2 Jahren Jahren NNP cord-015369-72cjogxz 4276 3 in in IN cord-015369-72cjogxz 4276 4 einem einem NNP cord-015369-72cjogxz 4276 5 Beobachtungszeitraum Beobachtungszeitraum NNP cord-015369-72cjogxz 4276 6 von von NNP cord-015369-72cjogxz 4276 7 einem einem NNP cord-015369-72cjogxz 4276 8 Jahr Jahr NNP cord-015369-72cjogxz 4276 9 . . . cord-015369-72cjogxz 4277 1 Results result NNS cord-015369-72cjogxz 4277 2 . . . cord-015369-72cjogxz 4278 1 Mean mean VB cord-015369-72cjogxz 4278 2 baseline baseline JJ cord-015369-72cjogxz 4278 3 hematocrit hematocrit NN cord-015369-72cjogxz 4278 4 serum serum NN cord-015369-72cjogxz 4278 5 levels level NNS cord-015369-72cjogxz 4278 6 were be VBD cord-015369-72cjogxz 4278 7 35.8 35.8 CD cord-015369-72cjogxz 4278 8 AE AE NNP cord-015369-72cjogxz 4278 9 6.3 6.3 CD cord-015369-72cjogxz 4278 10 % % NN cord-015369-72cjogxz 4278 11 . . . cord-015369-72cjogxz 4279 1 The the DT cord-015369-72cjogxz 4279 2 mean mean JJ cord-015369-72cjogxz 4279 3 decrease decrease NN cord-015369-72cjogxz 4279 4 of of IN cord-015369-72cjogxz 4279 5 hematocrit hematocrit NN cord-015369-72cjogxz 4279 6 serum serum NN cord-015369-72cjogxz 4279 7 levels level NNS cord-015369-72cjogxz 4279 8 was be VBD cord-015369-72cjogxz 4279 9 20.0 20.0 CD cord-015369-72cjogxz 4279 10 AE AE NNP cord-015369-72cjogxz 4279 11 21.1 21.1 CD cord-015369-72cjogxz 4279 12 % % NN cord-015369-72cjogxz 4279 13 after after IN cord-015369-72cjogxz 4279 14 surgery surgery NN cord-015369-72cjogxz 4279 15 . . . cord-015369-72cjogxz 4280 1 The the DT cord-015369-72cjogxz 4280 2 mean mean JJ cord-015369-72cjogxz 4280 3 decrease decrease NN cord-015369-72cjogxz 4280 4 of of IN cord-015369-72cjogxz 4280 5 hematocrit hematocrit NN cord-015369-72cjogxz 4280 6 serum serum NN cord-015369-72cjogxz 4280 7 levels level NNS cord-015369-72cjogxz 4280 8 in in IN cord-015369-72cjogxz 4280 9 patients patient NNS cord-015369-72cjogxz 4280 10 undergoing undergo VBG cord-015369-72cjogxz 4280 11 CABG CABG NNP cord-015369-72cjogxz 4280 12 without without IN cord-015369-72cjogxz 4280 13 CPB CPB NNP cord-015369-72cjogxz 4280 14 was be VBD cord-015369-72cjogxz 4280 15 12.5 12.5 CD cord-015369-72cjogxz 4280 16 AE AE NNP cord-015369-72cjogxz 4280 17 5.4 5.4 CD cord-015369-72cjogxz 4280 18 % % NN cord-015369-72cjogxz 4280 19 and and CC cord-015369-72cjogxz 4280 20 12.0 12.0 CD cord-015369-72cjogxz 4280 21 AE AE NNP cord-015369-72cjogxz 4280 22 20.0 20.0 CD cord-015369-72cjogxz 4280 23 % % NN cord-015369-72cjogxz 4280 24 in in IN cord-015369-72cjogxz 4280 25 patients patient NNS cord-015369-72cjogxz 4280 26 after after IN cord-015369-72cjogxz 4280 27 isolated isolate VBN cord-015369-72cjogxz 4280 28 valve valve NN cord-015369-72cjogxz 4280 29 replacement replacement NN cord-015369-72cjogxz 4280 30 . . . cord-015369-72cjogxz 4281 1 One one CD cord-015369-72cjogxz 4281 2 patient patient NN cord-015369-72cjogxz 4281 3 died die VBD cord-015369-72cjogxz 4281 4 during during IN cord-015369-72cjogxz 4281 5 the the DT cord-015369-72cjogxz 4281 6 operation operation NN cord-015369-72cjogxz 4281 7 . . . cord-015369-72cjogxz 4282 1 Four four CD cord-015369-72cjogxz 4282 2 patients patient NNS cord-015369-72cjogxz 4282 3 died die VBD cord-015369-72cjogxz 4282 4 in in IN cord-015369-72cjogxz 4282 5 the the DT cord-015369-72cjogxz 4282 6 postoperative postoperative JJ cord-015369-72cjogxz 4282 7 period period NN cord-015369-72cjogxz 4282 8 due due IN cord-015369-72cjogxz 4282 9 to to IN cord-015369-72cjogxz 4282 10 anemia anemia NN cord-015369-72cjogxz 4282 11 . . . cord-015369-72cjogxz 4283 1 During during IN cord-015369-72cjogxz 4283 2 followup followup NN cord-015369-72cjogxz 4283 3 , , , cord-015369-72cjogxz 4283 4 being be VBG cord-015369-72cjogxz 4283 5 33 33 CD cord-015369-72cjogxz 4283 6 AE AE NNP cord-015369-72cjogxz 4283 7 34 34 CD cord-015369-72cjogxz 4283 8 months month NNS cord-015369-72cjogxz 4283 9 to to IN cord-015369-72cjogxz 4283 10 date date NN cord-015369-72cjogxz 4283 11 , , , cord-015369-72cjogxz 4283 12 no no DT cord-015369-72cjogxz 4283 13 cardiovascular cardiovascular JJ cord-015369-72cjogxz 4283 14 related relate VBN cord-015369-72cjogxz 4283 15 adverse adverse JJ cord-015369-72cjogxz 4283 16 event event NN cord-015369-72cjogxz 4283 17 has have VBZ cord-015369-72cjogxz 4283 18 been be VBN cord-015369-72cjogxz 4283 19 observed observe VBN cord-015369-72cjogxz 4283 20 . . . cord-015369-72cjogxz 4284 1 Conclusions conclusion NNS cord-015369-72cjogxz 4284 2 . . . cord-015369-72cjogxz 4285 1 The the DT cord-015369-72cjogxz 4285 2 decrease decrease NN cord-015369-72cjogxz 4285 3 of of IN cord-015369-72cjogxz 4285 4 hematocrit hematocrit NN cord-015369-72cjogxz 4285 5 serum serum NN cord-015369-72cjogxz 4285 6 levels level NNS cord-015369-72cjogxz 4285 7 is be VBZ cord-015369-72cjogxz 4285 8 significantly significantly RB cord-015369-72cjogxz 4285 9 characterizing characterize VBG cord-015369-72cjogxz 4285 10 the the DT cord-015369-72cjogxz 4285 11 postoperative postoperative JJ cord-015369-72cjogxz 4285 12 period period NN cord-015369-72cjogxz 4285 13 of of IN cord-015369-72cjogxz 4285 14 open open JJ cord-015369-72cjogxz 4285 15 heart heart NN cord-015369-72cjogxz 4285 16 surgery surgery NN cord-015369-72cjogxz 4285 17 in in IN cord-015369-72cjogxz 4285 18 Jehovah Jehovah NNP cord-015369-72cjogxz 4285 19 's 's POS cord-015369-72cjogxz 4285 20 Witnesses Witnesses NNPS cord-015369-72cjogxz 4285 21 . . . cord-015369-72cjogxz 4286 1 In in IN cord-015369-72cjogxz 4286 2 patients patient NNS cord-015369-72cjogxz 4286 3 undergoing undergo VBG cord-015369-72cjogxz 4286 4 CABG CABG NNP cord-015369-72cjogxz 4286 5 without without IN cord-015369-72cjogxz 4286 6 CPB CPB NNP cord-015369-72cjogxz 4286 7 and and CC cord-015369-72cjogxz 4286 8 in in IN cord-015369-72cjogxz 4286 9 patients patient NNS cord-015369-72cjogxz 4286 10 undergoing undergo VBG cord-015369-72cjogxz 4286 11 isolated isolated JJ cord-015369-72cjogxz 4286 12 valve valve NN cord-015369-72cjogxz 4286 13 replacement replacement NN cord-015369-72cjogxz 4286 14 , , , cord-015369-72cjogxz 4286 15 decrease decrease NN cord-015369-72cjogxz 4286 16 of of IN cord-015369-72cjogxz 4286 17 hematocrit hematocrit NN cord-015369-72cjogxz 4286 18 serum serum NN cord-015369-72cjogxz 4286 19 levels level NNS cord-015369-72cjogxz 4286 20 was be VBD cord-015369-72cjogxz 4286 21 lowest low JJS cord-015369-72cjogxz 4286 22 . . . cord-015369-72cjogxz 4287 1 Therefore therefore RB cord-015369-72cjogxz 4287 2 , , , cord-015369-72cjogxz 4287 3 these these DT cord-015369-72cjogxz 4287 4 techniques technique NNS cord-015369-72cjogxz 4287 5 should should MD cord-015369-72cjogxz 4287 6 be be VB cord-015369-72cjogxz 4287 7 considered consider VBN cord-015369-72cjogxz 4287 8 for for IN cord-015369-72cjogxz 4287 9 first first JJ cord-015369-72cjogxz 4287 10 choice choice NN cord-015369-72cjogxz 4287 11 when when WRB cord-015369-72cjogxz 4287 12 appropriate appropriate JJ cord-015369-72cjogxz 4287 13 . . . cord-015369-72cjogxz 4288 1 Furthermore furthermore RB cord-015369-72cjogxz 4288 2 , , , cord-015369-72cjogxz 4288 3 highly highly RB cord-015369-72cjogxz 4288 4 normal normal JJ cord-015369-72cjogxz 4288 5 preoperative preoperative JJ cord-015369-72cjogxz 4288 6 hematocrit hematocrit NN cord-015369-72cjogxz 4288 7 serum serum NN cord-015369-72cjogxz 4288 8 levels level NNS cord-015369-72cjogxz 4288 9 and and CC cord-015369-72cjogxz 4288 10 a a DT cord-015369-72cjogxz 4288 11 meticulous meticulous JJ cord-015369-72cjogxz 4288 12 surgical surgical JJ cord-015369-72cjogxz 4288 13 technique technique NN cord-015369-72cjogxz 4288 14 remain remain VBP cord-015369-72cjogxz 4288 15 the the DT cord-015369-72cjogxz 4288 16 mainstay mainstay NN cord-015369-72cjogxz 4288 17 of of IN cord-015369-72cjogxz 4288 18 therapy therapy NN cord-015369-72cjogxz 4288 19 in in IN cord-015369-72cjogxz 4288 20 these these DT cord-015369-72cjogxz 4288 21 patients patient NNS cord-015369-72cjogxz 4288 22 . . . cord-015369-72cjogxz 4289 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4289 2 . . . cord-015369-72cjogxz 4290 1 Routinemäßige Routinemäßige NNP cord-015369-72cjogxz 4291 1 intraoperative intraoperative JJ cord-015369-72cjogxz 4291 2 Flussmessung Flussmessung NNP cord-015369-72cjogxz 4291 3 von von NNP cord-015369-72cjogxz 4291 4 Bypassgrafts Bypassgrafts NNP cord-015369-72cjogxz 4291 5 dient dient NNP cord-015369-72cjogxz 4291 6 der der NNP cord-015369-72cjogxz 4291 7 Qualitätssicherung Qualitätssicherung NNP cord-015369-72cjogxz 4291 8 koronarer koronarer NNP cord-015369-72cjogxz 4291 9 Revaskularisation Revaskularisation NNP cord-015369-72cjogxz 4291 10 . . . cord-015369-72cjogxz 4292 1 Ziel Ziel NNP cord-015369-72cjogxz 4292 2 unserer unserer JJ cord-015369-72cjogxz 4292 3 Studie Studie NNP cord-015369-72cjogxz 4292 4 war war NN cord-015369-72cjogxz 4292 5 die die VBP cord-015369-72cjogxz 4292 6 Evaluierung Evaluierung NNP cord-015369-72cjogxz 4292 7 der der NNP cord-015369-72cjogxz 4292 8 Flussmessung Flussmessung NNP cord-015369-72cjogxz 4292 9 als als NNP cord-015369-72cjogxz 4292 10 Indikator Indikator NNP cord-015369-72cjogxz 4292 11 für für IN cord-015369-72cjogxz 4292 12 Langzeitmortalität Langzeitmortalität NNP cord-015369-72cjogxz 4292 13 . . . cord-015369-72cjogxz 4293 1 Methodik Methodik NNP cord-015369-72cjogxz 4293 2 . . . cord-015369-72cjogxz 4294 1 Wir Wir NNP cord-015369-72cjogxz 4294 2 messen messen NNP cord-015369-72cjogxz 4294 3 routinemäßig routinemäßig NNP cord-015369-72cjogxz 4294 4 intraoperativ intraoperativ NNP cord-015369-72cjogxz 4294 5 die die VB cord-015369-72cjogxz 4294 6 Flussgeschwindigkeit Flussgeschwindigkeit NNP cord-015369-72cjogxz 4294 7 in in IN cord-015369-72cjogxz 4294 8 Bypassgrafts Bypassgrafts NNP cord-015369-72cjogxz 4294 9 mit mit NNP cord-015369-72cjogxz 4294 10 dem dem NNP cord-015369-72cjogxz 4294 11 Doppler Doppler NNP cord-015369-72cjogxz 4294 12 - - HYPH cord-015369-72cjogxz 4294 13 Flowmeter Flowmeter NNP cord-015369-72cjogxz 4294 14 ( ( -LRB- cord-015369-72cjogxz 4294 15 Cardiomed Cardiomed NNP cord-015369-72cjogxz 4294 16 + + CC cord-015369-72cjogxz 4294 17 ) ) -RRB- cord-015369-72cjogxz 4295 1 und und NNP cord-015369-72cjogxz 4296 1 speichern speichern NNP cord-015369-72cjogxz 4296 2 die die VBP cord-015369-72cjogxz 4296 3 Daten Daten NNP cord-015369-72cjogxz 4296 4 in in IN cord-015369-72cjogxz 4296 5 der der NNP cord-015369-72cjogxz 4296 6 ARCHIMED ARCHIMED NNP cord-015369-72cjogxz 4296 7 Datenbank Datenbank NNP cord-015369-72cjogxz 4296 8 . . . cord-015369-72cjogxz 4297 1 Fü fü NN cord-015369-72cjogxz 4298 1 r r LS cord-015369-72cjogxz 4298 2 diese diese NNP cord-015369-72cjogxz 4298 3 Studie Studie NNP cord-015369-72cjogxz 4299 1 analysierten analysierten NNP cord-015369-72cjogxz 4299 2 wir wir NNP cord-015369-72cjogxz 4299 3 retrospektiv retrospektiv RB cord-015369-72cjogxz 4300 1 Flussmessungen Flussmessungen NNP cord-015369-72cjogxz 4300 2 von von NNP cord-015369-72cjogxz 4300 3 1596 1596 CD cord-015369-72cjogxz 4301 1 CABG CABG NNP cord-015369-72cjogxz 4301 2 Patienten Patienten NNP cord-015369-72cjogxz 4301 3 , , , cord-015369-72cjogxz 4301 4 Euroscore Euroscore NNP cord-015369-72cjogxz 4301 5 , , , cord-015369-72cjogxz 4301 6 LVEF LVEF NNP cord-015369-72cjogxz 4301 7 , , , cord-015369-72cjogxz 4301 8 Alter Alter NNP cord-015369-72cjogxz 4301 9 , , , cord-015369-72cjogxz 4301 10 Geschlecht Geschlecht NNP cord-015369-72cjogxz 4301 11 fü fü IN cord-015369-72cjogxz 4301 12 r r NN cord-015369-72cjogxz 4301 13 den den NNP cord-015369-72cjogxz 4301 14 Beobachtungszeitraum Beobachtungszeitraum NNP cord-015369-72cjogxz 4301 15 1998 1998 CD cord-015369-72cjogxz 4301 16 - - SYM cord-015369-72cjogxz 4301 17 2006 2006 CD cord-015369-72cjogxz 4301 18 . . . cord-015369-72cjogxz 4302 1 Flussmessungen Flussmessungen NNP cord-015369-72cjogxz 4302 2 < < XX cord-015369-72cjogxz 4303 1 10 10 CD cord-015369-72cjogxz 4303 2 ml ml NN cord-015369-72cjogxz 4303 3 / / SYM cord-015369-72cjogxz 4303 4 min min NN cord-015369-72cjogxz 4303 5 > > XX cord-015369-72cjogxz 4303 6 125 125 CD cord-015369-72cjogxz 4303 7 ml ml NN cord-015369-72cjogxz 4303 8 / / SYM cord-015369-72cjogxz 4303 9 min min NNP cord-015369-72cjogxz 4303 10 wurden wurden NNP cord-015369-72cjogxz 4303 11 exkludiert exkludiert NNP cord-015369-72cjogxz 4303 12 . . . cord-015369-72cjogxz 4304 1 Wir Wir NNP cord-015369-72cjogxz 4304 2 unterteilten unterteilten NNP cord-015369-72cjogxz 4304 3 die die VBP cord-015369-72cjogxz 4304 4 Patienten Patienten NNP cord-015369-72cjogxz 4304 5 in in IN cord-015369-72cjogxz 4304 6 3 3 CD cord-015369-72cjogxz 4304 7 Gruppen Gruppen NNP cord-015369-72cjogxz 4304 8 : : : cord-015369-72cjogxz 4305 1 CABG CABG NNP cord-015369-72cjogxz 4305 2 I -PRON- PRP cord-015369-72cjogxz 4305 3 ( ( -LRB- cord-015369-72cjogxz 4305 4 Gruppe Gruppe NNP cord-015369-72cjogxz 4305 5 A A NNP cord-015369-72cjogxz 4305 6 ) ) -RRB- cord-015369-72cjogxz 4305 7 , , , cord-015369-72cjogxz 4305 8 CABG CABG NNP cord-015369-72cjogxz 4305 9 II II NNP cord-015369-72cjogxz 4305 10 ( ( -LRB- cord-015369-72cjogxz 4305 11 Gruppe Gruppe NNP cord-015369-72cjogxz 4305 12 II II NNP cord-015369-72cjogxz 4305 13 ) ) -RRB- cord-015369-72cjogxz 4305 14 , , , cord-015369-72cjogxz 4305 15 CABG CABG NNP cord-015369-72cjogxz 4305 16 III III NNP cord-015369-72cjogxz 4305 17 ( ( -LRB- cord-015369-72cjogxz 4305 18 Gruppe Gruppe NNP cord-015369-72cjogxz 4305 19 III III NNP cord-015369-72cjogxz 4305 20 ) ) -RRB- cord-015369-72cjogxz 4305 21 . . . cord-015369-72cjogxz 4306 1 Mittlerer Mittlerer NNP cord-015369-72cjogxz 4306 2 Beobachtunszeitraum Beobachtunszeitraum NNP cord-015369-72cjogxz 4306 3 war war NN cord-015369-72cjogxz 4306 4 8,8 8,8 CD cord-015369-72cjogxz 4306 5 Jahre Jahre NNP cord-015369-72cjogxz 4306 6 . . . cord-015369-72cjogxz 4307 1 Die die VB cord-015369-72cjogxz 4307 2 Datenerfassung Datenerfassung NNP cord-015369-72cjogxz 4307 3 war war NN cord-015369-72cjogxz 4307 4 vollständig vollständig NNP cord-015369-72cjogxz 4307 5 und und NNP cord-015369-72cjogxz 4307 6 mit mit NNP cord-015369-72cjogxz 4307 7 dem dem NNP cord-015369-72cjogxz 4307 8 Ö Ö NNP cord-015369-72cjogxz 4307 9 sterreichischen sterreichischen NN cord-015369-72cjogxz 4307 10 Sterberegister Sterberegister NNP cord-015369-72cjogxz 4307 11 abgeglichen abgeglichen NNP cord-015369-72cjogxz 4307 12 . . . cord-015369-72cjogxz 4308 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4308 2 . . . cord-015369-72cjogxz 4309 1 Gruppe Gruppe NNP cord-015369-72cjogxz 4309 2 A A NNP cord-015369-72cjogxz 4309 3 : : : cord-015369-72cjogxz 4309 4 mittlerer mittlerer NN cord-015369-72cjogxz 4309 5 ES ES NNP cord-015369-72cjogxz 4309 6 5 5 CD cord-015369-72cjogxz 4309 7 ( ( -LRB- cord-015369-72cjogxz 4309 8 3 3 CD cord-015369-72cjogxz 4309 9 - - SYM cord-015369-72cjogxz 4309 10 10 10 CD cord-015369-72cjogxz 4309 11 ) ) -RRB- cord-015369-72cjogxz 4310 1 und und IN cord-015369-72cjogxz 4310 2 mittlere mittlere RB cord-015369-72cjogxz 4310 3 LVEF LVEF NNP cord-015369-72cjogxz 4310 4 64 64 CD cord-015369-72cjogxz 4310 5 ( ( -LRB- cord-015369-72cjogxz 4310 6 33 33 CD cord-015369-72cjogxz 4310 7 - - SYM cord-015369-72cjogxz 4310 8 67 67 CD cord-015369-72cjogxz 4310 9 ) ) -RRB- cord-015369-72cjogxz 4310 10 hatte hatte NNP cord-015369-72cjogxz 4310 11 eine eine NNP cord-015369-72cjogxz 4311 1 mittlere mittlere RB cord-015369-72cjogxz 4312 1 Flussgeschwindigkeit Flussgeschwindigkeit NNP cord-015369-72cjogxz 4312 2 von von NNP cord-015369-72cjogxz 4312 3 46 46 CD cord-015369-72cjogxz 4312 4 ml/ ml/ JJ cord-015369-72cjogxz 4312 5 min min NN cord-015369-72cjogxz 4312 6 ( ( -LRB- cord-015369-72cjogxz 4312 7 20 20 CD cord-015369-72cjogxz 4312 8 - - SYM cord-015369-72cjogxz 4312 9 56 56 CD cord-015369-72cjogxz 4312 10 ) ) -RRB- cord-015369-72cjogxz 4312 11 , , , cord-015369-72cjogxz 4312 12 mit mit NNP cord-015369-72cjogxz 4312 13 Arteria Arteria NNP cord-015369-72cjogxz 4312 14 mammaria mammaria NNP cord-015369-72cjogxz 4312 15 interna interna NNP cord-015369-72cjogxz 4312 16 ( ( -LRB- cord-015369-72cjogxz 4312 17 IMA IMA NNP cord-015369-72cjogxz 4312 18 ) ) -RRB- cord-015369-72cjogxz 4312 19 39 39 CD cord-015369-72cjogxz 4312 20 ml ml NN cord-015369-72cjogxz 4312 21 / / SYM cord-015369-72cjogxz 4312 22 min min NN cord-015369-72cjogxz 4312 23 ( ( -LRB- cord-015369-72cjogxz 4312 24 28 28 CD cord-015369-72cjogxz 4312 25 - - SYM cord-015369-72cjogxz 4312 26 56 56 CD cord-015369-72cjogxz 4312 27 ) ) -RRB- cord-015369-72cjogxz 4312 28 , , , cord-015369-72cjogxz 4312 29 ohne ohne NNP cord-015369-72cjogxz 4312 30 IMA IMA NNP cord-015369-72cjogxz 4312 31 45.5 45.5 CD cord-015369-72cjogxz 4312 32 ml ml NNS cord-015369-72cjogxz 4312 33 / / SYM cord-015369-72cjogxz 4312 34 min min NN cord-015369-72cjogxz 4312 35 ( ( -LRB- cord-015369-72cjogxz 4312 36 20 20 CD cord-015369-72cjogxz 4312 37 - - SYM cord-015369-72cjogxz 4312 38 55 55 CD cord-015369-72cjogxz 4312 39 ) ) -RRB- cord-015369-72cjogxz 4312 40 . . . cord-015369-72cjogxz 4313 1 Altersdurchschnitt Altersdurchschnitt NNP cord-015369-72cjogxz 4313 2 72.3 72.3 CD cord-015369-72cjogxz 4313 3 Jahre Jahre NNP cord-015369-72cjogxz 4313 4 ( ( -LRB- cord-015369-72cjogxz 4313 5 71.8 71.8 CD cord-015369-72cjogxz 4313 6 - - HYPH cord-015369-72cjogxz 4313 7 74.9 74.9 CD cord-015369-72cjogxz 4313 8 ) ) -RRB- cord-015369-72cjogxz 4313 9 . . . cord-015369-72cjogxz 4314 1 m m NNP cord-015369-72cjogxz 4314 2 / / SYM cord-015369-72cjogxz 4314 3 w w NNP cord-015369-72cjogxz 4314 4 ¼ ¼ NNP cord-015369-72cjogxz 4314 5 58%/42 58%/42 CD cord-015369-72cjogxz 4314 6 % % NN cord-015369-72cjogxz 4314 7 . . . cord-015369-72cjogxz 4315 1 Langzeitmortalität Langzeitmortalität NNP cord-015369-72cjogxz 4315 2 von von NNP cord-015369-72cjogxz 4315 3 Gruppe Gruppe NNP cord-015369-72cjogxz 4315 4 A a DT cord-015369-72cjogxz 4315 5 war war NN cord-015369-72cjogxz 4315 6 8 8 CD cord-015369-72cjogxz 4315 7 % % NN cord-015369-72cjogxz 4315 8 . . . cord-015369-72cjogxz 4316 1 Gruppe Gruppe NNP cord-015369-72cjogxz 4316 2 B B NNP cord-015369-72cjogxz 4316 3 : : : cord-015369-72cjogxz 4316 4 mittlerer mittlerer NN cord-015369-72cjogxz 4316 5 ES ES NNP cord-015369-72cjogxz 4316 6 3 3 CD cord-015369-72cjogxz 4316 7 ( ( -LRB- cord-015369-72cjogxz 4316 8 2 2 CD cord-015369-72cjogxz 4316 9 - - SYM cord-015369-72cjogxz 4316 10 11 11 CD cord-015369-72cjogxz 4316 11 ) ) -RRB- cord-015369-72cjogxz 4316 12 und und CC cord-015369-72cjogxz 4316 13 mittlere mittlere RB cord-015369-72cjogxz 4316 14 LVEF LVEF NNP cord-015369-72cjogxz 4316 15 61 61 CD cord-015369-72cjogxz 4317 1 ( ( -LRB- cord-015369-72cjogxz 4317 2 43.5 43.5 CD cord-015369-72cjogxz 4317 3 - - SYM cord-015369-72cjogxz 4317 4 64 64 CD cord-015369-72cjogxz 4317 5 ) ) -RRB- cord-015369-72cjogxz 4317 6 hatte hatte NNP cord-015369-72cjogxz 4317 7 eine eine NNP cord-015369-72cjogxz 4317 8 mittlere mittlere RB cord-015369-72cjogxz 4318 1 Flussgeschwindigkeit Flussgeschwindigkeit NNP cord-015369-72cjogxz 4318 2 von von NNP cord-015369-72cjogxz 4318 3 66 66 CD cord-015369-72cjogxz 4318 4 ml ml NNS cord-015369-72cjogxz 4318 5 / / SYM cord-015369-72cjogxz 4318 6 min min NN cord-015369-72cjogxz 4318 7 ( ( -LRB- cord-015369-72cjogxz 4318 8 36 36 CD cord-015369-72cjogxz 4318 9 - - SYM cord-015369-72cjogxz 4318 10 104 104 CD cord-015369-72cjogxz 4318 11 ) ) -RRB- cord-015369-72cjogxz 4318 12 . . . cord-015369-72cjogxz 4319 1 Altersdurchschnitt Altersdurchschnitt NNP cord-015369-72cjogxz 4319 2 66.4 66.4 CD cord-015369-72cjogxz 4319 3 Jahre Jahre NNP cord-015369-72cjogxz 4319 4 ( ( -LRB- cord-015369-72cjogxz 4319 5 65 65 CD cord-015369-72cjogxz 4319 6 - - SYM cord-015369-72cjogxz 4319 7 71.7 71.7 CD cord-015369-72cjogxz 4319 8 ) ) -RRB- cord-015369-72cjogxz 4319 9 . . . cord-015369-72cjogxz 4320 1 m/ m/ NNP cord-015369-72cjogxz 4320 2 w w NNP cord-015369-72cjogxz 4321 1 ¼ ¼ NNP cord-015369-72cjogxz 4321 2 83%/17 83%/17 CD cord-015369-72cjogxz 4321 3 % % NN cord-015369-72cjogxz 4321 4 . . . cord-015369-72cjogxz 4322 1 Langzeitmortalität Langzeitmortalität NNP cord-015369-72cjogxz 4322 2 von von NNP cord-015369-72cjogxz 4322 3 Gruppe Gruppe NNP cord-015369-72cjogxz 4322 4 B B NNP cord-015369-72cjogxz 4322 5 war war NN cord-015369-72cjogxz 4322 6 10.3 10.3 CD cord-015369-72cjogxz 4322 7 % % NN cord-015369-72cjogxz 4322 8 . . . cord-015369-72cjogxz 4323 1 Gruppe Gruppe NNP cord-015369-72cjogxz 4323 2 C C NNP cord-015369-72cjogxz 4323 3 : : : cord-015369-72cjogxz 4323 4 mittlerer mittlerer NN cord-015369-72cjogxz 4323 5 ES ES NNP cord-015369-72cjogxz 4323 6 3 3 CD cord-015369-72cjogxz 4323 7 ( ( -LRB- cord-015369-72cjogxz 4323 8 3 3 CD cord-015369-72cjogxz 4323 9 - - SYM cord-015369-72cjogxz 4323 10 8 8 CD cord-015369-72cjogxz 4323 11 ) ) -RRB- cord-015369-72cjogxz 4323 12 und und CC cord-015369-72cjogxz 4323 13 mittlere mittlere RB cord-015369-72cjogxz 4323 14 LVEF LVEF NNP cord-015369-72cjogxz 4323 15 62 62 CD cord-015369-72cjogxz 4323 16 ( ( -LRB- cord-015369-72cjogxz 4323 17 52 52 CD cord-015369-72cjogxz 4323 18 - - SYM cord-015369-72cjogxz 4323 19 71.5 71.5 CD cord-015369-72cjogxz 4323 20 ) ) -RRB- cord-015369-72cjogxz 4323 21 hatte hatte NNP cord-015369-72cjogxz 4324 1 eine eine NNP cord-015369-72cjogxz 4324 2 mittlere mittlere RB cord-015369-72cjogxz 4325 1 Flussgeschwindigkeit Flussgeschwindigkeit NNP cord-015369-72cjogxz 4325 2 von von NNP cord-015369-72cjogxz 4325 3 47 47 CD cord-015369-72cjogxz 4325 4 ml ml NNS cord-015369-72cjogxz 4325 5 / / SYM cord-015369-72cjogxz 4325 6 min min NN cord-015369-72cjogxz 4325 7 ( ( -LRB- cord-015369-72cjogxz 4325 8 32 32 CD cord-015369-72cjogxz 4325 9 - - SYM cord-015369-72cjogxz 4325 10 53 53 CD cord-015369-72cjogxz 4325 11 ) ) -RRB- cord-015369-72cjogxz 4325 12 . . . cord-015369-72cjogxz 4326 1 Altersdurchschnitt Altersdurchschnitt NNP cord-015369-72cjogxz 4326 2 68.4 68.4 CD cord-015369-72cjogxz 4326 3 Jahre Jahre NNP cord-015369-72cjogxz 4326 4 ( ( -LRB- cord-015369-72cjogxz 4326 5 68 68 CD cord-015369-72cjogxz 4326 6 - - SYM cord-015369-72cjogxz 4326 7 71.4 71.4 CD cord-015369-72cjogxz 4326 8 ) ) -RRB- cord-015369-72cjogxz 4326 9 . . . cord-015369-72cjogxz 4327 1 m m NNP cord-015369-72cjogxz 4327 2 / / SYM cord-015369-72cjogxz 4327 3 w w NNP cord-015369-72cjogxz 4327 4 ¼ ¼ NNP cord-015369-72cjogxz 4327 5 75%/25 75%/25 CD cord-015369-72cjogxz 4327 6 % % NN cord-015369-72cjogxz 4327 7 . . . cord-015369-72cjogxz 4328 1 Langzeitmortalität Langzeitmortalität NNP cord-015369-72cjogxz 4328 2 von von NNP cord-015369-72cjogxz 4328 3 Gruppe Gruppe NNP cord-015369-72cjogxz 4328 4 C C NNP cord-015369-72cjogxz 4328 5 war war NN cord-015369-72cjogxz 4328 6 4.5 4.5 CD cord-015369-72cjogxz 4328 7 % % NN cord-015369-72cjogxz 4328 8 . . . cord-015369-72cjogxz 4329 1 Gesamtlangzeitmortalität Gesamtlangzeitmortalität NNP cord-015369-72cjogxz 4329 2 war war NN cord-015369-72cjogxz 4329 3 10.2 10.2 CD cord-015369-72cjogxz 4329 4 % % NN cord-015369-72cjogxz 4329 5 . . . cord-015369-72cjogxz 4330 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4330 2 . . . cord-015369-72cjogxz 4331 1 Zwischen Zwischen NNP cord-015369-72cjogxz 4331 2 den den NN cord-015369-72cjogxz 4331 3 3 3 CD cord-015369-72cjogxz 4331 4 Gruppen Gruppen NNP cord-015369-72cjogxz 4331 5 zeigte zeigte NNP cord-015369-72cjogxz 4331 6 sich sich NNP cord-015369-72cjogxz 4331 7 kein kein NNP cord-015369-72cjogxz 4331 8 signifikanter signifikanter NNP cord-015369-72cjogxz 4331 9 Unterschied Unterschied NNP cord-015369-72cjogxz 4331 10 bezü bezü NNP cord-015369-72cjogxz 4331 11 glich glich NNP cord-015369-72cjogxz 4331 12 ES ES NNP cord-015369-72cjogxz 4331 13 , , , cord-015369-72cjogxz 4331 14 LVEF LVEF NNP cord-015369-72cjogxz 4331 15 oder oder NNP cord-015369-72cjogxz 4331 16 Flussgeschwindigkeit Flussgeschwindigkeit NNP cord-015369-72cjogxz 4331 17 und und IN cord-015369-72cjogxz 4331 18 keine keine NNP cord-015369-72cjogxz 4331 19 signifikante signifikante NNP cord-015369-72cjogxz 4331 20 Korrelation Korrelation NNP cord-015369-72cjogxz 4331 21 derer derer NNP cord-015369-72cjogxz 4331 22 zur zur NNP cord-015369-72cjogxz 4331 23 Mortalität Mortalität NNP cord-015369-72cjogxz 4331 24 . . . cord-015369-72cjogxz 4332 1 Flussgeschwindigkeit Flussgeschwindigkeit NNP cord-015369-72cjogxz 4332 2 ist ist NN cord-015369-72cjogxz 4332 3 kein kein NNP cord-015369-72cjogxz 4332 4 Indikator Indikator NNP cord-015369-72cjogxz 4332 5 fü fü IN cord-015369-72cjogxz 4332 6 r r NNP cord-015369-72cjogxz 4332 7 Langzeitmortalität Langzeitmortalität NNP cord-015369-72cjogxz 4332 8 . . . cord-015369-72cjogxz 4333 1 The the DT cord-015369-72cjogxz 4333 2 radial radial JJ cord-015369-72cjogxz 4333 3 artery artery NN cord-015369-72cjogxz 4333 4 as as IN cord-015369-72cjogxz 4333 5 arterial arterial JJ cord-015369-72cjogxz 4333 6 bypass bypass NN cord-015369-72cjogxz 4333 7 graft graft NN cord-015369-72cjogxz 4333 8 in in IN cord-015369-72cjogxz 4333 9 coronary coronary JJ cord-015369-72cjogxz 4333 10 surgeryreport surgeryreport NN cord-015369-72cjogxz 4333 11 of of IN cord-015369-72cjogxz 4333 12 an an DT cord-015369-72cjogxz 4333 13 angiographic angiographic JJ cord-015369-72cjogxz 4333 14 evaluation evaluation NN cord-015369-72cjogxz 4333 15 with with IN cord-015369-72cjogxz 4333 16 64-or 64-or CD cord-015369-72cjogxz 4333 17 320multi 320multi JJ cord-015369-72cjogxz 4333 18 - - HYPH cord-015369-72cjogxz 4333 19 slice slice NN cord-015369-72cjogxz 4333 20 computed compute VBN cord-015369-72cjogxz 4333 21 tomography tomography NN cord-015369-72cjogxz 4333 22 K. K. NNP cord-015369-72cjogxz 4333 23 Mészáros Mészáros NNP cord-015369-72cjogxz 4333 24 , , , cord-015369-72cjogxz 4333 25 A. A. NNP cord-015369-72cjogxz 4333 26 Yates Yates NNP cord-015369-72cjogxz 4333 27 , , , cord-015369-72cjogxz 4333 28 F. F. NNP cord-015369-72cjogxz 4333 29 Dobaja Dobaja NNP cord-015369-72cjogxz 4334 1 Klinische Klinische NNP cord-015369-72cjogxz 4334 2 Abteilung Abteilung NNP cord-015369-72cjogxz 4334 3 für für IN cord-015369-72cjogxz 4334 4 Herzchirurgie Herzchirurgie NNP cord-015369-72cjogxz 4334 5 , , , cord-015369-72cjogxz 4334 6 Graz Graz NNP cord-015369-72cjogxz 4334 7 , , , cord-015369-72cjogxz 4334 8 Austria Austria NNP cord-015369-72cjogxz 4334 9 Background Background NNP cord-015369-72cjogxz 4334 10 . . . cord-015369-72cjogxz 4335 1 Since since IN cord-015369-72cjogxz 4335 2 2001 2001 CD cord-015369-72cjogxz 4335 3 , , , cord-015369-72cjogxz 4335 4 the the DT cord-015369-72cjogxz 4335 5 radial radial JJ cord-015369-72cjogxz 4335 6 artery artery NN cord-015369-72cjogxz 4335 7 , , , cord-015369-72cjogxz 4335 8 additionally additionally RB cord-015369-72cjogxz 4335 9 to to IN cord-015369-72cjogxz 4335 10 LITA LITA NNP cord-015369-72cjogxz 4335 11 and and CC cord-015369-72cjogxz 4335 12 RITA RITA NNP cord-015369-72cjogxz 4335 13 , , , cord-015369-72cjogxz 4335 14 was be VBD cord-015369-72cjogxz 4335 15 used use VBN cord-015369-72cjogxz 4335 16 as as IN cord-015369-72cjogxz 4335 17 arterial arterial JJ cord-015369-72cjogxz 4335 18 bypass bypass NN cord-015369-72cjogxz 4335 19 graft graft NN cord-015369-72cjogxz 4335 20 material material NN cord-015369-72cjogxz 4335 21 in in IN cord-015369-72cjogxz 4335 22 160 160 CD cord-015369-72cjogxz 4335 23 CABG CABG NNP cord-015369-72cjogxz 4335 24 pts pt NNS cord-015369-72cjogxz 4335 25 at at IN cord-015369-72cjogxz 4335 26 our -PRON- PRP$ cord-015369-72cjogxz 4335 27 institution institution NN cord-015369-72cjogxz 4335 28 . . . cord-015369-72cjogxz 4336 1 The the DT cord-015369-72cjogxz 4336 2 aim aim NN cord-015369-72cjogxz 4336 3 of of IN cord-015369-72cjogxz 4336 4 this this DT cord-015369-72cjogxz 4336 5 study study NN cord-015369-72cjogxz 4336 6 is be VBZ cord-015369-72cjogxz 4336 7 the the DT cord-015369-72cjogxz 4336 8 evaluation evaluation NN cord-015369-72cjogxz 4336 9 of of IN cord-015369-72cjogxz 4336 10 radial radial JJ cord-015369-72cjogxz 4336 11 artery artery NN cord-015369-72cjogxz 4336 12 patency patency NN cord-015369-72cjogxz 4336 13 and and CC cord-015369-72cjogxz 4336 14 stenosis stenosis NN cord-015369-72cjogxz 4336 15 with with IN cord-015369-72cjogxz 4336 16 CTangiography CTangiography NNP cord-015369-72cjogxz 4336 17 . . . cord-015369-72cjogxz 4336 18 Methods method NNS cord-015369-72cjogxz 4336 19 . . . cord-015369-72cjogxz 4337 1 Before before IN cord-015369-72cjogxz 4337 2 scanning scanning NN cord-015369-72cjogxz 4337 3 , , , cord-015369-72cjogxz 4337 4 all all DT cord-015369-72cjogxz 4337 5 patients patient NNS cord-015369-72cjogxz 4337 6 were be VBD cord-015369-72cjogxz 4337 7 clinically clinically RB cord-015369-72cjogxz 4337 8 examined examine VBN cord-015369-72cjogxz 4337 9 and and CC cord-015369-72cjogxz 4337 10 had have VBD cord-015369-72cjogxz 4337 11 to to TO cord-015369-72cjogxz 4337 12 fill fill VB cord-015369-72cjogxz 4337 13 in in RP cord-015369-72cjogxz 4337 14 a a DT cord-015369-72cjogxz 4337 15 questionnaire questionnaire NN cord-015369-72cjogxz 4337 16 concerning concern VBG cord-015369-72cjogxz 4337 17 their -PRON- PRP$ cord-015369-72cjogxz 4337 18 current current JJ cord-015369-72cjogxz 4337 19 NYHA NYHA NNP cord-015369-72cjogxz 4337 20 - - : cord-015369-72cjogxz 4337 21 and and CC cord-015369-72cjogxz 4337 22 CCS CCS NNP cord-015369-72cjogxz 4337 23 - - HYPH cord-015369-72cjogxz 4337 24 state state NN cord-015369-72cjogxz 4337 25 , , , cord-015369-72cjogxz 4337 26 their -PRON- PRP$ cord-015369-72cjogxz 4337 27 medication medication NN cord-015369-72cjogxz 4337 28 and and CC cord-015369-72cjogxz 4337 29 risk risk NN cord-015369-72cjogxz 4337 30 factors factor NNS cord-015369-72cjogxz 4337 31 . . . cord-015369-72cjogxz 4338 1 All all DT cord-015369-72cjogxz 4338 2 patients patient NNS cord-015369-72cjogxz 4338 3 were be VBD cord-015369-72cjogxz 4338 4 examined examine VBN cord-015369-72cjogxz 4338 5 for for IN cord-015369-72cjogxz 4338 6 presence presence NN cord-015369-72cjogxz 4338 7 of of IN cord-015369-72cjogxz 4338 8 restrictions restriction NNS cord-015369-72cjogxz 4338 9 resulting result VBG cord-015369-72cjogxz 4338 10 from from IN cord-015369-72cjogxz 4338 11 radial radial JJ cord-015369-72cjogxz 4338 12 artery artery NN cord-015369-72cjogxz 4338 13 harvesting harvesting NN cord-015369-72cjogxz 4338 14 in in IN cord-015369-72cjogxz 4338 15 the the DT cord-015369-72cjogxz 4338 16 concerned concerned JJ cord-015369-72cjogxz 4338 17 arm arm NN cord-015369-72cjogxz 4338 18 ( ( -LRB- cord-015369-72cjogxz 4338 19 fine fine JJ cord-015369-72cjogxz 4338 20 motor motor NN cord-015369-72cjogxz 4338 21 skills skill NNS cord-015369-72cjogxz 4338 22 , , , cord-015369-72cjogxz 4338 23 sensibility sensibility NN cord-015369-72cjogxz 4338 24 , , , cord-015369-72cjogxz 4338 25 perfusion perfusion NN cord-015369-72cjogxz 4338 26 etc etc NN cord-015369-72cjogxz 4338 27 . . . cord-015369-72cjogxz 4338 28 ) ) -RRB- cord-015369-72cjogxz 4338 29 . . . cord-015369-72cjogxz 4339 1 After after IN cord-015369-72cjogxz 4339 2 that that DT cord-015369-72cjogxz 4339 3 , , , cord-015369-72cjogxz 4339 4 the the DT cord-015369-72cjogxz 4339 5 recent recent JJ cord-015369-72cjogxz 4339 6 creatinine creatinine NN cord-015369-72cjogxz 4339 7 - - HYPH cord-015369-72cjogxz 4339 8 level level NN cord-015369-72cjogxz 4339 9 was be VBD cord-015369-72cjogxz 4339 10 analyzed analyze VBN cord-015369-72cjogxz 4339 11 in in IN cord-015369-72cjogxz 4339 12 all all DT cord-015369-72cjogxz 4339 13 patients patient NNS cord-015369-72cjogxz 4339 14 . . . cord-015369-72cjogxz 4340 1 CT CT NNP cord-015369-72cjogxz 4340 2 was be VBD cord-015369-72cjogxz 4340 3 performed perform VBN cord-015369-72cjogxz 4340 4 in in IN cord-015369-72cjogxz 4340 5 one one CD cord-015369-72cjogxz 4340 6 group group NN cord-015369-72cjogxz 4340 7 with with IN cord-015369-72cjogxz 4340 8 a a DT cord-015369-72cjogxz 4340 9 new new JJ cord-015369-72cjogxz 4340 10 320-slice 320-slice CD cord-015369-72cjogxz 4340 11 CT CT NNP cord-015369-72cjogxz 4340 12 - - HYPH cord-015369-72cjogxz 4340 13 Scanner Scanner NNP cord-015369-72cjogxz 4340 14 and and CC cord-015369-72cjogxz 4340 15 in in IN cord-015369-72cjogxz 4340 16 the the DT cord-015369-72cjogxz 4340 17 other other JJ cord-015369-72cjogxz 4340 18 group group NN cord-015369-72cjogxz 4340 19 with with IN cord-015369-72cjogxz 4340 20 a a DT cord-015369-72cjogxz 4340 21 64-Slice 64-slice CD cord-015369-72cjogxz 4340 22 scanner scanner NN cord-015369-72cjogxz 4340 23 , , , cord-015369-72cjogxz 4340 24 depending depend VBG cord-015369-72cjogxz 4340 25 on on IN cord-015369-72cjogxz 4340 26 the the DT cord-015369-72cjogxz 4340 27 availability availability NN cord-015369-72cjogxz 4340 28 of of IN cord-015369-72cjogxz 4340 29 the the DT cord-015369-72cjogxz 4340 30 scanner scanner NN cord-015369-72cjogxz 4340 31 . . . cord-015369-72cjogxz 4341 1 Graft graft NN cord-015369-72cjogxz 4341 2 patency patency NN cord-015369-72cjogxz 4341 3 and and CC cord-015369-72cjogxz 4341 4 stenosis stenosis NN cord-015369-72cjogxz 4341 5 was be VBD cord-015369-72cjogxz 4341 6 analyzed analyze VBN cord-015369-72cjogxz 4341 7 in in IN cord-015369-72cjogxz 4341 8 cooperation cooperation NN cord-015369-72cjogxz 4341 9 of of IN cord-015369-72cjogxz 4341 10 cardiac cardiac JJ cord-015369-72cjogxz 4341 11 surgeons surgeon NNS cord-015369-72cjogxz 4341 12 and and CC cord-015369-72cjogxz 4341 13 radiologists radiologist NNS cord-015369-72cjogxz 4341 14 in in IN cord-015369-72cjogxz 4341 15 several several JJ cord-015369-72cjogxz 4341 16 reconstruction reconstruction NN cord-015369-72cjogxz 4341 17 techniques technique NNS cord-015369-72cjogxz 4341 18 . . . cord-015369-72cjogxz 4342 1 Results result NNS cord-015369-72cjogxz 4342 2 . . . cord-015369-72cjogxz 4343 1 Preliminary preliminary JJ cord-015369-72cjogxz 4343 2 data datum NNS cord-015369-72cjogxz 4343 3 of of IN cord-015369-72cjogxz 4343 4 18 18 CD cord-015369-72cjogxz 4343 5 pts pt NNS cord-015369-72cjogxz 4343 6 showed show VBD cord-015369-72cjogxz 4343 7 4 4 CD cord-015369-72cjogxz 4343 8 radial radial JJ cord-015369-72cjogxz 4343 9 artery artery NN cord-015369-72cjogxz 4343 10 occlusions occlusion NNS cord-015369-72cjogxz 4343 11 , , , cord-015369-72cjogxz 4343 12 in in IN cord-015369-72cjogxz 4343 13 all all DT cord-015369-72cjogxz 4343 14 other other JJ cord-015369-72cjogxz 4343 15 cases case NNS cord-015369-72cjogxz 4343 16 ( ( -LRB- cord-015369-72cjogxz 4343 17 77 77 CD cord-015369-72cjogxz 4343 18 % % NN cord-015369-72cjogxz 4343 19 ) ) -RRB- cord-015369-72cjogxz 4343 20 , , , cord-015369-72cjogxz 4343 21 radial radial JJ cord-015369-72cjogxz 4343 22 artery artery NN cord-015369-72cjogxz 4343 23 was be VBD cord-015369-72cjogxz 4343 24 widely widely RB cord-015369-72cjogxz 4343 25 patent patent NN cord-015369-72cjogxz 4343 26 after after IN cord-015369-72cjogxz 4344 1 a a DT cord-015369-72cjogxz 4344 2 mean mean NN cord-015369-72cjogxz 4344 3 follow follow VB cord-015369-72cjogxz 4344 4 up up IN cord-015369-72cjogxz 4344 5 of of IN cord-015369-72cjogxz 4344 6 50 50 CD cord-015369-72cjogxz 4344 7 AE AE NNP cord-015369-72cjogxz 4344 8 8 8 CD cord-015369-72cjogxz 4344 9 months month NNS cord-015369-72cjogxz 4344 10 . . . cord-015369-72cjogxz 4345 1 Conclusions conclusion NNS cord-015369-72cjogxz 4345 2 . . . cord-015369-72cjogxz 4346 1 At at IN cord-015369-72cjogxz 4346 2 present present NN cord-015369-72cjogxz 4346 3 , , , cord-015369-72cjogxz 4346 4 the the DT cord-015369-72cjogxz 4346 5 examination examination NN cord-015369-72cjogxz 4346 6 is be VBZ cord-015369-72cjogxz 4346 7 still still RB cord-015369-72cjogxz 4346 8 under under IN cord-015369-72cjogxz 4346 9 proceeding proceeding NN cord-015369-72cjogxz 4346 10 . . . cord-015369-72cjogxz 4347 1 First first JJ cord-015369-72cjogxz 4347 2 results result NNS cord-015369-72cjogxz 4347 3 showed show VBD cord-015369-72cjogxz 4347 4 quite quite RB cord-015369-72cjogxz 4347 5 satisfying satisfying JJ cord-015369-72cjogxz 4347 6 results result NNS cord-015369-72cjogxz 4347 7 in in IN cord-015369-72cjogxz 4347 8 radial radial JJ cord-015369-72cjogxz 4347 9 artery artery NN cord-015369-72cjogxz 4347 10 patency patency NN cord-015369-72cjogxz 4347 11 , , , cord-015369-72cjogxz 4347 12 data datum NNS cord-015369-72cjogxz 4347 13 from from IN cord-015369-72cjogxz 4347 14 all all DT cord-015369-72cjogxz 4347 15 pts pt NNS cord-015369-72cjogxz 4347 16 will will MD cord-015369-72cjogxz 4347 17 show show VB cord-015369-72cjogxz 4347 18 statistical statistical JJ cord-015369-72cjogxz 4347 19 significant significant JJ cord-015369-72cjogxz 4347 20 factors factor NNS cord-015369-72cjogxz 4347 21 impairing impair VBG cord-015369-72cjogxz 4347 22 radial radial JJ cord-015369-72cjogxz 4347 23 artery artery NN cord-015369-72cjogxz 4347 24 patency patency NN cord-015369-72cjogxz 4347 25 . . . cord-015369-72cjogxz 4348 1 These these DT cord-015369-72cjogxz 4348 2 data datum NNS cord-015369-72cjogxz 4348 3 will will MD cord-015369-72cjogxz 4348 4 help help VB cord-015369-72cjogxz 4348 5 us -PRON- PRP cord-015369-72cjogxz 4348 6 to to TO cord-015369-72cjogxz 4348 7 improve improve VB cord-015369-72cjogxz 4348 8 long long JJ cord-015369-72cjogxz 4348 9 term term NN cord-015369-72cjogxz 4348 10 patency patency NN cord-015369-72cjogxz 4348 11 rate rate NN cord-015369-72cjogxz 4348 12 of of IN cord-015369-72cjogxz 4348 13 radial radial JJ cord-015369-72cjogxz 4348 14 bypass bypass NN cord-015369-72cjogxz 4348 15 conduits conduit NNS cord-015369-72cjogxz 4348 16 . . . cord-015369-72cjogxz 4349 1 Surgical surgical JJ cord-015369-72cjogxz 4349 2 therapy therapy NN cord-015369-72cjogxz 4349 3 options option NNS cord-015369-72cjogxz 4349 4 in in IN cord-015369-72cjogxz 4349 5 Ebstein Ebstein NNP cord-015369-72cjogxz 4349 6 's 's POS cord-015369-72cjogxz 4349 7 anomaly anomaly NN cord-015369-72cjogxz 4349 8 in in IN cord-015369-72cjogxz 4349 9 adults adult NNS cord-015369-72cjogxz 4349 10 N. N. NNP cord-015369-72cjogxz 4349 11 Reiss Reiss NNP cord-015369-72cjogxz 4349 12 , , , cord-015369-72cjogxz 4349 13 U. U. NNP cord-015369-72cjogxz 4349 14 Schütt Schütt NNP cord-015369-72cjogxz 4349 15 , , , cord-015369-72cjogxz 4349 16 R. R. NNP cord-015369-72cjogxz 4349 17 Körfer Körfer NNP cord-015369-72cjogxz 4349 18 , , , cord-015369-72cjogxz 4349 19 J. J. NNP cord-015369-72cjogxz 4349 20 Gummert Gummert NNP cord-015369-72cjogxz 4349 21 Background Background NNP cord-015369-72cjogxz 4349 22 . . . cord-015369-72cjogxz 4350 1 Ebstein Ebstein NNP cord-015369-72cjogxz 4350 2 's 's POS cord-015369-72cjogxz 4350 3 anomaly anomaly NN cord-015369-72cjogxz 4350 4 is be VBZ cord-015369-72cjogxz 4350 5 a a DT cord-015369-72cjogxz 4350 6 rare rare JJ cord-015369-72cjogxz 4350 7 congenital congenital JJ cord-015369-72cjogxz 4350 8 malformation malformation NN cord-015369-72cjogxz 4350 9 of of IN cord-015369-72cjogxz 4350 10 the the DT cord-015369-72cjogxz 4350 11 heart heart NN cord-015369-72cjogxz 4350 12 , , , cord-015369-72cjogxz 4350 13 the the DT cord-015369-72cjogxz 4350 14 basic basic JJ cord-015369-72cjogxz 4350 15 feature feature NN cord-015369-72cjogxz 4350 16 of of IN cord-015369-72cjogxz 4350 17 which which WDT cord-015369-72cjogxz 4350 18 is be VBZ cord-015369-72cjogxz 4350 19 dislocation dislocation NN cord-015369-72cjogxz 4350 20 of of IN cord-015369-72cjogxz 4350 21 the the DT cord-015369-72cjogxz 4350 22 tricuspid tricuspid NN cord-015369-72cjogxz 4350 23 valve valve NN cord-015369-72cjogxz 4350 24 into into IN cord-015369-72cjogxz 4350 25 the the DT cord-015369-72cjogxz 4350 26 right right JJ cord-015369-72cjogxz 4350 27 ventricular ventricular JJ cord-015369-72cjogxz 4350 28 cavity cavity NN cord-015369-72cjogxz 4350 29 . . . cord-015369-72cjogxz 4351 1 The the DT cord-015369-72cjogxz 4351 2 onset onset NN cord-015369-72cjogxz 4351 3 of of IN cord-015369-72cjogxz 4351 4 the the DT cord-015369-72cjogxz 4351 5 symptoms symptom NNS cord-015369-72cjogxz 4351 6 and and CC cord-015369-72cjogxz 4351 7 the the DT cord-015369-72cjogxz 4351 8 diagnosis diagnosis NN cord-015369-72cjogxz 4351 9 depend depend VBP cord-015369-72cjogxz 4351 10 on on IN cord-015369-72cjogxz 4351 11 the the DT cord-015369-72cjogxz 4351 12 severity severity NN cord-015369-72cjogxz 4351 13 of of IN cord-015369-72cjogxz 4351 14 the the DT cord-015369-72cjogxz 4351 15 valve valve NN cord-015369-72cjogxz 4351 16 dysfunction dysfunction NN cord-015369-72cjogxz 4351 17 and and CC cord-015369-72cjogxz 4351 18 the the DT cord-015369-72cjogxz 4351 19 right right JJ cord-015369-72cjogxz 4351 20 ventricular ventricular JJ cord-015369-72cjogxz 4351 21 function function NN cord-015369-72cjogxz 4351 22 and and CC cord-015369-72cjogxz 4351 23 size size NN cord-015369-72cjogxz 4351 24 . . . cord-015369-72cjogxz 4352 1 The the DT cord-015369-72cjogxz 4352 2 age age NN cord-015369-72cjogxz 4352 3 at at IN cord-015369-72cjogxz 4352 4 diagnosis diagnosis NN cord-015369-72cjogxz 4352 5 ranges range VBZ cord-015369-72cjogxz 4352 6 from from IN cord-015369-72cjogxz 4352 7 birth birth NN cord-015369-72cjogxz 4352 8 to to IN cord-015369-72cjogxz 4352 9 adulthood adulthood NN cord-015369-72cjogxz 4352 10 . . . cord-015369-72cjogxz 4353 1 We -PRON- PRP cord-015369-72cjogxz 4353 2 report report VBP cord-015369-72cjogxz 4353 3 our -PRON- PRP$ cord-015369-72cjogxz 4353 4 experience experience NN cord-015369-72cjogxz 4353 5 with with IN cord-015369-72cjogxz 4353 6 surgical surgical JJ cord-015369-72cjogxz 4353 7 treatment treatment NN cord-015369-72cjogxz 4353 8 of of IN cord-015369-72cjogxz 4353 9 Ebstein Ebstein NNP cord-015369-72cjogxz 4353 10 's 's POS cord-015369-72cjogxz 4353 11 anomaly anomaly NN cord-015369-72cjogxz 4353 12 in in IN cord-015369-72cjogxz 4353 13 adults adult NNS cord-015369-72cjogxz 4353 14 . . . cord-015369-72cjogxz 4354 1 Methods method NNS cord-015369-72cjogxz 4354 2 . . . cord-015369-72cjogxz 4355 1 Twenty twenty CD cord-015369-72cjogxz 4355 2 - - HYPH cord-015369-72cjogxz 4355 3 three three CD cord-015369-72cjogxz 4355 4 pts pt NNS cord-015369-72cjogxz 4355 5 ( ( -LRB- cord-015369-72cjogxz 4355 6 11 11 CD cord-015369-72cjogxz 4355 7 male male NN cord-015369-72cjogxz 4355 8 , , , cord-015369-72cjogxz 4355 9 12 12 CD cord-015369-72cjogxz 4355 10 female female NN cord-015369-72cjogxz 4355 11 , , , cord-015369-72cjogxz 4355 12 mean mean VB cord-015369-72cjogxz 4355 13 age age NN cord-015369-72cjogxz 4355 14 48 48 CD cord-015369-72cjogxz 4355 15 years year NNS cord-015369-72cjogxz 4355 16 , , , cord-015369-72cjogxz 4355 17 21 21 CD cord-015369-72cjogxz 4355 18 to to TO cord-015369-72cjogxz 4355 19 75 75 CD cord-015369-72cjogxz 4355 20 years year NNS cord-015369-72cjogxz 4355 21 ) ) -RRB- cord-015369-72cjogxz 4355 22 underwent undergo VBD cord-015369-72cjogxz 4355 23 surgical surgical JJ cord-015369-72cjogxz 4355 24 treatment treatment NN cord-015369-72cjogxz 4355 25 in in IN cord-015369-72cjogxz 4355 26 Ebstein Ebstein NNP cord-015369-72cjogxz 4355 27 's 's POS cord-015369-72cjogxz 4355 28 anomaly anomaly NN cord-015369-72cjogxz 4355 29 ( ( -LRB- cord-015369-72cjogxz 4355 30 tricuspid tricuspid NN cord-015369-72cjogxz 4355 31 valve valve NN cord-015369-72cjogxz 4355 32 repair repair NN cord-015369-72cjogxz 4355 33 in in IN cord-015369-72cjogxz 4355 34 various various JJ cord-015369-72cjogxz 4355 35 techniques technique NNS cord-015369-72cjogxz 4356 1 ¼ ¼ NNP cord-015369-72cjogxz 4356 2 11 11 CD cord-015369-72cjogxz 4356 3 , , , cord-015369-72cjogxz 4356 4 tricuspid tricuspid NN cord-015369-72cjogxz 4356 5 valve valve NN cord-015369-72cjogxz 4356 6 replacement replacement NN cord-015369-72cjogxz 4356 7 ¼ ¼ NNP cord-015369-72cjogxz 4356 8 9 9 CD cord-015369-72cjogxz 4356 9 ( ( -LRB- cord-015369-72cjogxz 4356 10 8 8 CD cord-015369-72cjogxz 4356 11 St. St. NNP cord-015369-72cjogxz 4356 12 Jude Jude NNP cord-015369-72cjogxz 4356 13 Medical Medical NNP cord-015369-72cjogxz 4356 14 , , , cord-015369-72cjogxz 4356 15 1 1 CD cord-015369-72cjogxz 4356 16 Hancock Hancock NNP cord-015369-72cjogxz 4356 17 ) ) -RRB- cord-015369-72cjogxz 4356 18 , , , cord-015369-72cjogxz 4356 19 and and CC cord-015369-72cjogxz 4356 20 heart heart NN cord-015369-72cjogxz 4356 21 transplantation transplantation NN cord-015369-72cjogxz 4356 22 ¼ ¼ NNP cord-015369-72cjogxz 4356 23 3 3 CD cord-015369-72cjogxz 4356 24 ) ) -RRB- cord-015369-72cjogxz 4356 25 . . . cord-015369-72cjogxz 4357 1 All all DT cord-015369-72cjogxz 4357 2 pts pt NNS cord-015369-72cjogxz 4357 3 with with IN cord-015369-72cjogxz 4357 4 mechanical mechanical JJ cord-015369-72cjogxz 4357 5 tricuspid tricuspid NN cord-015369-72cjogxz 4357 6 valve valve NN cord-015369-72cjogxz 4357 7 replacement replacement NN cord-015369-72cjogxz 4357 8 were be VBD cord-015369-72cjogxz 4357 9 introduced introduce VBN cord-015369-72cjogxz 4357 10 in in IN cord-015369-72cjogxz 4357 11 INR INR NNP cord-015369-72cjogxz 4357 12 - - HYPH cord-015369-72cjogxz 4357 13 self self NN cord-015369-72cjogxz 4357 14 - - HYPH cord-015369-72cjogxz 4357 15 management management NN cord-015369-72cjogxz 4357 16 . . . cord-015369-72cjogxz 4358 1 Only only RB cord-015369-72cjogxz 4358 2 four four CD cord-015369-72cjogxz 4358 3 of of IN cord-015369-72cjogxz 4358 4 the the DT cord-015369-72cjogxz 4358 5 23 23 CD cord-015369-72cjogxz 4358 6 patients patient NNS cord-015369-72cjogxz 4358 7 had have VBD cord-015369-72cjogxz 4358 8 previous previous JJ cord-015369-72cjogxz 4358 9 cardiac cardiac JJ cord-015369-72cjogxz 4358 10 surgery surgery NN cord-015369-72cjogxz 4358 11 . . . cord-015369-72cjogxz 4359 1 Results result NNS cord-015369-72cjogxz 4359 2 . . . cord-015369-72cjogxz 4360 1 Twenty twenty CD cord-015369-72cjogxz 4360 2 pts pt NNS cord-015369-72cjogxz 4360 3 recovered recover VBN cord-015369-72cjogxz 4360 4 well well RB cord-015369-72cjogxz 4360 5 after after IN cord-015369-72cjogxz 4360 6 surgery surgery NN cord-015369-72cjogxz 4360 7 . . . cord-015369-72cjogxz 4361 1 Three three CD cord-015369-72cjogxz 4361 2 pts pt NNS cord-015369-72cjogxz 4361 3 developed develop VBD cord-015369-72cjogxz 4361 4 cardiac cardiac JJ cord-015369-72cjogxz 4361 5 low low JJ cord-015369-72cjogxz 4361 6 - - HYPH cord-015369-72cjogxz 4361 7 output output NN cord-015369-72cjogxz 4361 8 - - HYPH cord-015369-72cjogxz 4361 9 syndrome syndrome NN cord-015369-72cjogxz 4361 10 , , , cord-015369-72cjogxz 4361 11 which which WDT cord-015369-72cjogxz 4361 12 was be VBD cord-015369-72cjogxz 4361 13 treated treat VBN cord-015369-72cjogxz 4361 14 by by IN cord-015369-72cjogxz 4361 15 implantation implantation NN cord-015369-72cjogxz 4361 16 of of IN cord-015369-72cjogxz 4361 17 mechanical mechanical JJ cord-015369-72cjogxz 4361 18 circulatory circulatory JJ cord-015369-72cjogxz 4361 19 support support NN cord-015369-72cjogxz 4361 20 systems system NNS cord-015369-72cjogxz 4361 21 ( ( -LRB- cord-015369-72cjogxz 4361 22 2 2 CD cord-015369-72cjogxz 4361 23 Thoratec Thoratec NNP cord-015369-72cjogxz 4361 24 , , , cord-015369-72cjogxz 4361 25 1 1 CD cord-015369-72cjogxz 4361 26 CardioWest CardioWest NNP cord-015369-72cjogxz 4361 27 ) ) -RRB- cord-015369-72cjogxz 4361 28 . . . cord-015369-72cjogxz 4362 1 One one CD cord-015369-72cjogxz 4362 2 pt pt NN cord-015369-72cjogxz 4362 3 could could MD cord-015369-72cjogxz 4362 4 be be VB cord-015369-72cjogxz 4362 5 weaned wean VBN cord-015369-72cjogxz 4362 6 , , , cord-015369-72cjogxz 4362 7 one one CD cord-015369-72cjogxz 4362 8 pt pt NN cord-015369-72cjogxz 4362 9 was be VBD cord-015369-72cjogxz 4362 10 successfully successfully RB cord-015369-72cjogxz 4362 11 bridged bridge VBN cord-015369-72cjogxz 4362 12 to to IN cord-015369-72cjogxz 4362 13 Htx Htx NNP cord-015369-72cjogxz 4362 14 and and CC cord-015369-72cjogxz 4362 15 one one CD cord-015369-72cjogxz 4362 16 pt pt NN cord-015369-72cjogxz 4362 17 died die VBD cord-015369-72cjogxz 4362 18 on on IN cord-015369-72cjogxz 4362 19 device device NN cord-015369-72cjogxz 4362 20 because because IN cord-015369-72cjogxz 4362 21 of of IN cord-015369-72cjogxz 4362 22 multiorgan multiorgan NNP cord-015369-72cjogxz 4362 23 failure failure NN cord-015369-72cjogxz 4362 24 . . . cord-015369-72cjogxz 4363 1 After after IN cord-015369-72cjogxz 4363 2 a a DT cord-015369-72cjogxz 4363 3 mean mean JJ cord-015369-72cjogxz 4363 4 time time NN cord-015369-72cjogxz 4363 5 of of IN cord-015369-72cjogxz 4363 6 5.5 5.5 CD cord-015369-72cjogxz 4363 7 years year NNS cord-015369-72cjogxz 4363 8 78 78 CD cord-015369-72cjogxz 4363 9 % % NN cord-015369-72cjogxz 4363 10 of of IN cord-015369-72cjogxz 4363 11 pts pt NNS cord-015369-72cjogxz 4363 12 were be VBD cord-015369-72cjogxz 4363 13 in in IN cord-015369-72cjogxz 4363 14 NYHA NYHA NNP cord-015369-72cjogxz 4363 15 class class NN cord-015369-72cjogxz 4363 16 I i NN cord-015369-72cjogxz 4363 17 or or CC cord-015369-72cjogxz 4363 18 II II NNP cord-015369-72cjogxz 4363 19 . . . cord-015369-72cjogxz 4364 1 Conclusions conclusion NNS cord-015369-72cjogxz 4364 2 . . . cord-015369-72cjogxz 4365 1 Surgical surgical JJ cord-015369-72cjogxz 4365 2 therapy therapy NN cord-015369-72cjogxz 4365 3 of of IN cord-015369-72cjogxz 4365 4 Ebstein Ebstein NNP cord-015369-72cjogxz 4365 5 's 's POS cord-015369-72cjogxz 4365 6 anomaly anomaly NN cord-015369-72cjogxz 4365 7 can can MD cord-015369-72cjogxz 4365 8 be be VB cord-015369-72cjogxz 4365 9 performed perform VBN cord-015369-72cjogxz 4365 10 with with IN cord-015369-72cjogxz 4365 11 good good JJ cord-015369-72cjogxz 4365 12 results result NNS cord-015369-72cjogxz 4365 13 in in IN cord-015369-72cjogxz 4365 14 the the DT cord-015369-72cjogxz 4365 15 adult adult NN cord-015369-72cjogxz 4365 16 population population NN cord-015369-72cjogxz 4365 17 . . . cord-015369-72cjogxz 4366 1 When when WRB cord-015369-72cjogxz 4366 2 valve valve NN cord-015369-72cjogxz 4366 3 repair repair NN cord-015369-72cjogxz 4366 4 is be VBZ cord-015369-72cjogxz 4366 5 not not RB cord-015369-72cjogxz 4366 6 feasible feasible JJ cord-015369-72cjogxz 4366 7 we -PRON- PRP cord-015369-72cjogxz 4366 8 prefer prefer VBP cord-015369-72cjogxz 4366 9 implantation implantation NN cord-015369-72cjogxz 4366 10 of of IN cord-015369-72cjogxz 4366 11 mechanical mechanical JJ cord-015369-72cjogxz 4366 12 valves valve NNS cord-015369-72cjogxz 4366 13 with with IN cord-015369-72cjogxz 4366 14 consecutive consecutive JJ cord-015369-72cjogxz 4366 15 INR INR NNP cord-015369-72cjogxz 4366 16 - - HYPH cord-015369-72cjogxz 4366 17 self self NN cord-015369-72cjogxz 4366 18 management management NN cord-015369-72cjogxz 4366 19 . . . cord-015369-72cjogxz 4367 1 Reduction reduction NN cord-015369-72cjogxz 4367 2 of of IN cord-015369-72cjogxz 4367 3 sternum sternum NN cord-015369-72cjogxz 4367 4 instability instability NN cord-015369-72cjogxz 4367 5 after after IN cord-015369-72cjogxz 4367 6 cardiac cardiac JJ cord-015369-72cjogxz 4367 7 surgery surgery NN cord-015369-72cjogxz 4367 8 with with IN cord-015369-72cjogxz 4367 9 a a DT cord-015369-72cjogxz 4367 10 newly newly RB cord-015369-72cjogxz 4367 11 designed design VBN cord-015369-72cjogxz 4367 12 thorax thorax NN cord-015369-72cjogxz 4367 13 support support NN cord-015369-72cjogxz 4367 14 vest vest NN cord-015369-72cjogxz 4367 15 Methodik Methodik NNP cord-015369-72cjogxz 4367 16 . . . cord-015369-72cjogxz 4368 1 In in IN cord-015369-72cjogxz 4368 2 einer einer FW cord-015369-72cjogxz 4368 3 prospektiv prospektiv FW cord-015369-72cjogxz 4368 4 randomisierten randomisierten FW cord-015369-72cjogxz 4368 5 Studie Studie NNP cord-015369-72cjogxz 4368 6 wurden wurden VBD cord-015369-72cjogxz 4368 7 455 455 CD cord-015369-72cjogxz 4368 8 Patienten Patienten NNP cord-015369-72cjogxz 4368 9 untersucht untersucht NN cord-015369-72cjogxz 4368 10 , , , cord-015369-72cjogxz 4368 11 die die VB cord-015369-72cjogxz 4368 12 einem einem FW cord-015369-72cjogxz 4368 13 herzchirurgischen herzchirurgischen NNP cord-015369-72cjogxz 4368 14 Eingriff Eingriff NNP cord-015369-72cjogxz 4368 15 unterzogen unterzogen NNP cord-015369-72cjogxz 4368 16 wurden wurden NNP cord-015369-72cjogxz 4368 17 . . . cord-015369-72cjogxz 4369 1 Die Die NNP cord-015369-72cjogxz 4369 2 Patienten Patienten NNP cord-015369-72cjogxz 4369 3 wurden wurden NNS cord-015369-72cjogxz 4369 4 in in IN cord-015369-72cjogxz 4369 5 zwei zwei CD cord-015369-72cjogxz 4369 6 Gruppen Gruppen NNP cord-015369-72cjogxz 4369 7 stratifiziert stratifiziert NNP cord-015369-72cjogxz 4369 8 : : : cord-015369-72cjogxz 4370 1 Gruppe Gruppe NNP cord-015369-72cjogxz 4370 2 A A NNP cord-015369-72cjogxz 4371 1 wurde wurde NNP cord-015369-72cjogxz 4371 2 unmittelbar unmittelbar NNP cord-015369-72cjogxz 4371 3 nach nach NNP cord-015369-72cjogxz 4371 4 der der NNP cord-015369-72cjogxz 4371 5 Herzoperation Herzoperation NNP cord-015369-72cjogxz 4371 6 mit mit NNP cord-015369-72cjogxz 4371 7 der der NNP cord-015369-72cjogxz 4371 8 Posthorax Posthorax NNP cord-015369-72cjogxz 4371 9 + + CC cord-015369-72cjogxz 4371 10 Herzweste Herzweste NNP cord-015369-72cjogxz 4371 11 ( ( -LRB- cord-015369-72cjogxz 4371 12 Fa Fa NNP cord-015369-72cjogxz 4371 13 . . . cord-015369-72cjogxz 4372 1 Epple Epple NNP cord-015369-72cjogxz 4372 2 , , , cord-015369-72cjogxz 4372 3 Wien Wien NNP cord-015369-72cjogxz 4372 4 ) ) -RRB- cord-015369-72cjogxz 4373 1 zur zur NNP cord-015369-72cjogxz 4373 2 Stabilisierung Stabilisierung NNP cord-015369-72cjogxz 4373 3 des des FW cord-015369-72cjogxz 4373 4 Sternums Sternums NNP cord-015369-72cjogxz 4373 5 behandelt behandelt NNP cord-015369-72cjogxz 4373 6 . . . cord-015369-72cjogxz 4374 1 Gruppe Gruppe NNP cord-015369-72cjogxz 4374 2 B B NNP cord-015369-72cjogxz 4374 3 wurde wurde NNP cord-015369-72cjogxz 4375 1 wie wie NNP cord-015369-72cjogxz 4375 2 bisher bisher NNP cord-015369-72cjogxz 4376 1 mit mit NNP cord-015369-72cjogxz 4376 2 einer einer NNP cord-015369-72cjogxz 4376 3 elastischen elastischen NNP cord-015369-72cjogxz 4376 4 Bandage Bandage NNP cord-015369-72cjogxz 4376 5 versorgt versorgt NN cord-015369-72cjogxz 4376 6 . . . cord-015369-72cjogxz 4377 1 Alle Alle NNP cord-015369-72cjogxz 4377 2 Patienten Patienten NNP cord-015369-72cjogxz 4377 3 wurden wurden VBD cord-015369-72cjogxz 4377 4 durch durch NNP cord-015369-72cjogxz 4377 5 einen einen NNP cord-015369-72cjogxz 4377 6 präoperativen präoperativen VBN cord-015369-72cjogxz 4377 7 Risikoscore Risikoscore NNP cord-015369-72cjogxz 4377 8 evaluiert evaluiert RB cord-015369-72cjogxz 4377 9 . . . cord-015369-72cjogxz 4378 1 Zahlreiche zahlreiche JJ cord-015369-72cjogxz 4378 2 operative operative NN cord-015369-72cjogxz 4378 3 , , , cord-015369-72cjogxz 4378 4 laborchemische laborchemische NNP cord-015369-72cjogxz 4378 5 und und NNP cord-015369-72cjogxz 4378 6 klinische klinische NNP cord-015369-72cjogxz 4378 7 Daten Daten NNP cord-015369-72cjogxz 4378 8 wurden wurden VBD cord-015369-72cjogxz 4378 9 anlaysiert anlaysiert RB cord-015369-72cjogxz 4378 10 . . . cord-015369-72cjogxz 4379 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4379 2 . . . cord-015369-72cjogxz 4380 1 Die die VB cord-015369-72cjogxz 4381 1 beiden beiden NNP cord-015369-72cjogxz 4381 2 randomisierten randomisierten NNP cord-015369-72cjogxz 4382 1 Gruppen Gruppen NNP cord-015369-72cjogxz 4382 2 waren waren NNP cord-015369-72cjogxz 4382 3 bis bis NNP cord-015369-72cjogxz 4382 4 auf auf NN cord-015369-72cjogxz 4382 5 das das NNP cord-015369-72cjogxz 4382 6 Vorliegen Vorliegen NNP cord-015369-72cjogxz 4382 7 von von NNP cord-015369-72cjogxz 4382 8 Diabetes Diabetes NNP cord-015369-72cjogxz 4382 9 , , , cord-015369-72cjogxz 4382 10 der der VB cord-015369-72cjogxz 4382 11 in in IN cord-015369-72cjogxz 4382 12 der der NNP cord-015369-72cjogxz 4382 13 Gruppe Gruppe NNP cord-015369-72cjogxz 4382 14 A A NNP cord-015369-72cjogxz 4382 15 häufiger häufiger FW cord-015369-72cjogxz 4382 16 zu zu NNP cord-015369-72cjogxz 4382 17 beobachten beobachten NNP cord-015369-72cjogxz 4382 18 war war NN cord-015369-72cjogxz 4382 19 , , , cord-015369-72cjogxz 4382 20 seitens seitens NNP cord-015369-72cjogxz 4382 21 der der NNP cord-015369-72cjogxz 4382 22 demographischen demographischen NNP cord-015369-72cjogxz 4382 23 , , , cord-015369-72cjogxz 4382 24 laborchemischen laborchemischen NNP cord-015369-72cjogxz 4382 25 und und NNP cord-015369-72cjogxz 4382 26 operativen operativen NNP cord-015369-72cjogxz 4382 27 Variablen Variablen NNP cord-015369-72cjogxz 4382 28 vergleichbar vergleichbar NN cord-015369-72cjogxz 4382 29 . . . cord-015369-72cjogxz 4383 1 15 15 CD cord-015369-72cjogxz 4383 2 ( ( -LRB- cord-015369-72cjogxz 4383 3 5,4 5,4 CD cord-015369-72cjogxz 4383 4 % % NN cord-015369-72cjogxz 4383 5 ) ) -RRB- cord-015369-72cjogxz 4384 1 Patienten Patienten NNP cord-015369-72cjogxz 4384 2 der der NNP cord-015369-72cjogxz 4384 3 Kontrollgruppe Kontrollgruppe NNP cord-015369-72cjogxz 4384 4 ohne ohne NNP cord-015369-72cjogxz 4384 5 Weste Weste NNP cord-015369-72cjogxz 4384 6 entwickelten entwickelten NNP cord-015369-72cjogxz 4384 7 Komplikationen Komplikationen NNP cord-015369-72cjogxz 4384 8 i -PRON- PRP cord-015369-72cjogxz 4384 9 m be VBP cord-015369-72cjogxz 4384 10 Bereich Bereich NNP cord-015369-72cjogxz 4384 11 der der NNP cord-015369-72cjogxz 4384 12 Sternumwunde Sternumwunde NNP cord-015369-72cjogxz 4384 13 , , , cord-015369-72cjogxz 4384 14 die die VB cord-015369-72cjogxz 4384 15 eine eine JJ cord-015369-72cjogxz 4384 16 Reoperation reoperation NN cord-015369-72cjogxz 4384 17 erforderte erforderte NN cord-015369-72cjogxz 4384 18 . . . cord-015369-72cjogxz 4385 1 In in IN cord-015369-72cjogxz 4385 2 der der NNP cord-015369-72cjogxz 4385 3 Gruppe Gruppe NNP cord-015369-72cjogxz 4385 4 A a DT cord-015369-72cjogxz 4385 5 musste musste JJ cord-015369-72cjogxz 4385 6 ein ein NNP cord-015369-72cjogxz 4385 7 Patient Patient NNP cord-015369-72cjogxz 4385 8 wegen wegen NNP cord-015369-72cjogxz 4385 9 einer einer NNP cord-015369-72cjogxz 4385 10 oberflächlichen oberflächlichen NNP cord-015369-72cjogxz 4386 1 Infektion Infektion NNP cord-015369-72cjogxz 4386 2 der der NNP cord-015369-72cjogxz 4386 3 Sternumwunde Sternumwunde NNP cord-015369-72cjogxz 4386 4 reoperiert reoperiert NN cord-015369-72cjogxz 4387 1 werden werden NNP cord-015369-72cjogxz 4387 2 ( ( -LRB- cord-015369-72cjogxz 4387 3 0,4 0,4 CD cord-015369-72cjogxz 4387 4 % % NN cord-015369-72cjogxz 4387 5 ) ) -RRB- cord-015369-72cjogxz 4387 6 . . . cord-015369-72cjogxz 4388 1 Dies die VBZ cord-015369-72cjogxz 4388 2 bedeutet bedeutet NNP cord-015369-72cjogxz 4388 3 einen einen NNP cord-015369-72cjogxz 4388 4 signifikanten signifikanten NNP cord-015369-72cjogxz 4388 5 Unterschied Unterschied NNP cord-015369-72cjogxz 4388 6 zwischen zwischen NNP cord-015369-72cjogxz 4388 7 den den NN cord-015369-72cjogxz 4388 8 beiden beiden JJ cord-015369-72cjogxz 4388 9 Gruppen Gruppen NNP cord-015369-72cjogxz 4388 10 bezü bezü NNP cord-015369-72cjogxz 4388 11 glich glich NNP cord-015369-72cjogxz 4388 12 des des NNP cord-015369-72cjogxz 4389 1 Auftretens Auftretens NNP cord-015369-72cjogxz 4389 2 von von NNP cord-015369-72cjogxz 4389 3 Sternumproblemen Sternumproblemen NNP cord-015369-72cjogxz 4390 1 ( ( -LRB- cord-015369-72cjogxz 4390 2 Exact Exact NNP cord-015369-72cjogxz 4390 3 Fisher Fisher NNP cord-015369-72cjogxz 4390 4 's 's POS cord-015369-72cjogxz 4390 5 Test test NN cord-015369-72cjogxz 4390 6 : : : cord-015369-72cjogxz 4390 7 0,0069 0,0069 CD cord-015369-72cjogxz 4390 8 ) ) -RRB- cord-015369-72cjogxz 4390 9 . . . cord-015369-72cjogxz 4391 1 Interessanterweise Interessanterweise NNP cord-015369-72cjogxz 4391 2 traten traten VBD cord-015369-72cjogxz 4391 3 25 25 CD cord-015369-72cjogxz 4391 4 % % NN cord-015369-72cjogxz 4391 5 der der NNP cord-015369-72cjogxz 4391 6 Komplikationen Komplikationen NNP cord-015369-72cjogxz 4391 7 nach nach NN cord-015369-72cjogxz 4391 8 dem dem NNP cord-015369-72cjogxz 4391 9 Spitalsaufenthalt Spitalsaufenthalt NNP cord-015369-72cjogxz 4391 10 innerhalb innerhalb NNP cord-015369-72cjogxz 4391 11 von von NNP cord-015369-72cjogxz 4391 12 90 90 CD cord-015369-72cjogxz 4391 13 Tagen Tagen NNP cord-015369-72cjogxz 4391 14 auf auf NNP cord-015369-72cjogxz 4391 15 . . . cord-015369-72cjogxz 4392 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4392 2 . . . cord-015369-72cjogxz 4393 1 Der Der NNP cord-015369-72cjogxz 4393 2 Gebrauch Gebrauch NNP cord-015369-72cjogxz 4393 3 der der NNP cord-015369-72cjogxz 4393 4 Posthorax Posthorax NNP cord-015369-72cjogxz 4393 5 + + SYM cord-015369-72cjogxz 4393 6 Herzweste Herzweste NNP cord-015369-72cjogxz 4393 7 zeigt zeigt NNP cord-015369-72cjogxz 4393 8 in in IN cord-015369-72cjogxz 4393 9 dieser dieser NNP cord-015369-72cjogxz 4393 10 prospektiv prospektiv NNP cord-015369-72cjogxz 4393 11 randomisierten randomisierten NNP cord-015369-72cjogxz 4394 1 Studie Studie NNP cord-015369-72cjogxz 4394 2 eine eine NNP cord-015369-72cjogxz 4394 3 deutliche deutliche NNP cord-015369-72cjogxz 4395 1 Senkung Senkung NNP cord-015369-72cjogxz 4395 2 der der NNP cord-015369-72cjogxz 4395 3 Komplikationen Komplikationen NNP cord-015369-72cjogxz 4396 1 i -PRON- PRP cord-015369-72cjogxz 4396 2 m be VBP cord-015369-72cjogxz 4397 1 Bereich Bereich NNP cord-015369-72cjogxz 4397 2 des des FW cord-015369-72cjogxz 4397 3 Sternum Sternum NNP cord-015369-72cjogxz 4397 4 nach nach NN cord-015369-72cjogxz 4397 5 herzchirurgischen herzchirurgischen NNP cord-015369-72cjogxz 4397 6 Eingriffen Eingriffen NNP cord-015369-72cjogxz 4397 7 . . . cord-015369-72cjogxz 4398 1 Background background NN cord-015369-72cjogxz 4398 2 . . . cord-015369-72cjogxz 4399 1 Sine sine VB cord-015369-72cjogxz 4399 2 the the DT cord-015369-72cjogxz 4399 3 quantity quantity NN cord-015369-72cjogxz 4399 4 of of IN cord-015369-72cjogxz 4399 5 ICD ICD NNP cord-015369-72cjogxz 4399 6 implantations implantation NNS cord-015369-72cjogxz 4399 7 is be VBZ cord-015369-72cjogxz 4399 8 steadily steadily RB cord-015369-72cjogxz 4399 9 increasing increase VBG cord-015369-72cjogxz 4399 10 the the DT cord-015369-72cjogxz 4399 11 numbers number NNS cord-015369-72cjogxz 4399 12 of of IN cord-015369-72cjogxz 4399 13 complications complication NNS cord-015369-72cjogxz 4399 14 is be VBZ cord-015369-72cjogxz 4399 15 rising rise VBG cord-015369-72cjogxz 4399 16 too too RB cord-015369-72cjogxz 4399 17 . . . cord-015369-72cjogxz 4400 1 One one CD cord-015369-72cjogxz 4400 2 of of IN cord-015369-72cjogxz 4400 3 the the DT cord-015369-72cjogxz 4400 4 issues issue NNS cord-015369-72cjogxz 4400 5 is be VBZ cord-015369-72cjogxz 4400 6 how how WRB cord-015369-72cjogxz 4400 7 to to TO cord-015369-72cjogxz 4400 8 deal deal VB cord-015369-72cjogxz 4400 9 with with IN cord-015369-72cjogxz 4400 10 damaged damage VBN cord-015369-72cjogxz 4400 11 or or CC cord-015369-72cjogxz 4400 12 infected infected JJ cord-015369-72cjogxz 4400 13 leads lead NNS cord-015369-72cjogxz 4400 14 . . . cord-015369-72cjogxz 4401 1 We -PRON- PRP cord-015369-72cjogxz 4401 2 report report VBP cord-015369-72cjogxz 4401 3 our -PRON- PRP$ cord-015369-72cjogxz 4401 4 experience experience NN cord-015369-72cjogxz 4401 5 with with IN cord-015369-72cjogxz 4401 6 ICD ICD NNP cord-015369-72cjogxz 4401 7 and and CC cord-015369-72cjogxz 4401 8 PM PM NNP cord-015369-72cjogxz 4401 9 lead lead VB cord-015369-72cjogxz 4401 10 extraction extraction NN cord-015369-72cjogxz 4401 11 , , , cord-015369-72cjogxz 4401 12 possibility possibility NN cord-015369-72cjogxz 4401 13 and and CC cord-015369-72cjogxz 4401 14 complications complication NNS cord-015369-72cjogxz 4401 15 . . . cord-015369-72cjogxz 4402 1 Methods method NNS cord-015369-72cjogxz 4402 2 . . . cord-015369-72cjogxz 4403 1 In in IN cord-015369-72cjogxz 4403 2 a a DT cord-015369-72cjogxz 4403 3 retrospective retrospective JJ cord-015369-72cjogxz 4403 4 analysis analysis NN cord-015369-72cjogxz 4403 5 percentage percentage NN cord-015369-72cjogxz 4403 6 of of IN cord-015369-72cjogxz 4403 7 lead lead JJ cord-015369-72cjogxz 4403 8 extraction extraction NN cord-015369-72cjogxz 4403 9 in in IN cord-015369-72cjogxz 4403 10 ICD ICD NNP cord-015369-72cjogxz 4403 11 patients patient NNS cord-015369-72cjogxz 4403 12 , , , cord-015369-72cjogxz 4403 13 duration duration NN cord-015369-72cjogxz 4403 14 of of IN cord-015369-72cjogxz 4403 15 operation operation NN cord-015369-72cjogxz 4403 16 and and CC cord-015369-72cjogxz 4403 17 complications complication NNS cord-015369-72cjogxz 4403 18 were be VBD cord-015369-72cjogxz 4403 19 evaluated evaluate VBN cord-015369-72cjogxz 4403 20 . . . cord-015369-72cjogxz 4404 1 Complications complication NNS cord-015369-72cjogxz 4404 2 were be VBD cord-015369-72cjogxz 4404 3 defined define VBN cord-015369-72cjogxz 4404 4 as as IN cord-015369-72cjogxz 4404 5 death death NN cord-015369-72cjogxz 4404 6 of of IN cord-015369-72cjogxz 4404 7 patient patient NN cord-015369-72cjogxz 4404 8 , , , cord-015369-72cjogxz 4404 9 surgery surgery NN cord-015369-72cjogxz 4404 10 repair repair NN cord-015369-72cjogxz 4404 11 of of IN cord-015369-72cjogxz 4404 12 vessel vessel NN cord-015369-72cjogxz 4404 13 , , , cord-015369-72cjogxz 4404 14 sternotomy sternotomy NN cord-015369-72cjogxz 4404 15 , , , cord-015369-72cjogxz 4404 16 blood blood NN cord-015369-72cjogxz 4404 17 transfusion transfusion NN cord-015369-72cjogxz 4404 18 , , , cord-015369-72cjogxz 4404 19 pericard pericard NNP cord-015369-72cjogxz 4404 20 effusion effusion NN cord-015369-72cjogxz 4404 21 , , , cord-015369-72cjogxz 4404 22 infection infection NN cord-015369-72cjogxz 4404 23 , , , cord-015369-72cjogxz 4404 24 pneumothorax pneumothorax NN cord-015369-72cjogxz 4404 25 , , , cord-015369-72cjogxz 4404 26 embolic embolic NN cord-015369-72cjogxz 4404 27 event event NN cord-015369-72cjogxz 4404 28 and and CC cord-015369-72cjogxz 4404 29 bleeding bleed VBG cord-015369-72cjogxz 4404 30 with with IN cord-015369-72cjogxz 4404 31 surgical surgical JJ cord-015369-72cjogxz 4404 32 revision revision NN cord-015369-72cjogxz 4404 33 . . . cord-015369-72cjogxz 4405 1 Extraction extraction NN cord-015369-72cjogxz 4405 2 was be VBD cord-015369-72cjogxz 4405 3 done do VBN cord-015369-72cjogxz 4405 4 either either CC cord-015369-72cjogxz 4405 5 by by IN cord-015369-72cjogxz 4405 6 manual manual JJ cord-015369-72cjogxz 4405 7 traction traction NN cord-015369-72cjogxz 4405 8 or or CC cord-015369-72cjogxz 4405 9 by by IN cord-015369-72cjogxz 4405 10 extraction extraction NN cord-015369-72cjogxz 4405 11 tool tool NN cord-015369-72cjogxz 4405 12 . . . cord-015369-72cjogxz 4406 1 Results result NNS cord-015369-72cjogxz 4406 2 Background Background NNP cord-015369-72cjogxz 4406 3 . . . cord-015369-72cjogxz 4407 1 To to TO cord-015369-72cjogxz 4407 2 evaluate evaluate VB cord-015369-72cjogxz 4407 3 histopathological histopathological JJ cord-015369-72cjogxz 4407 4 findings finding NNS cord-015369-72cjogxz 4407 5 of of IN cord-015369-72cjogxz 4407 6 intraoperatively intraoperatively RB cord-015369-72cjogxz 4407 7 gained gain VBN cord-015369-72cjogxz 4407 8 aortic aortic JJ cord-015369-72cjogxz 4407 9 specimens specimen NNS cord-015369-72cjogxz 4407 10 . . . cord-015369-72cjogxz 4408 1 Methods method NNS cord-015369-72cjogxz 4408 2 . . . cord-015369-72cjogxz 4409 1 Between between IN cord-015369-72cjogxz 4409 2 January January NNP cord-015369-72cjogxz 4409 3 2003 2003 CD cord-015369-72cjogxz 4409 4 and and CC cord-015369-72cjogxz 4409 5 October October NNP cord-015369-72cjogxz 4409 6 2008 2008 CD cord-015369-72cjogxz 4409 7 , , , cord-015369-72cjogxz 4409 8 aortic aortic JJ cord-015369-72cjogxz 4409 9 specimens specimen NNS cord-015369-72cjogxz 4409 10 were be VBD cord-015369-72cjogxz 4409 11 evaluated evaluate VBN cord-015369-72cjogxz 4409 12 in in IN cord-015369-72cjogxz 4409 13 142 142 CD cord-015369-72cjogxz 4409 14 patients patient NNS cord-015369-72cjogxz 4409 15 including include VBG cord-015369-72cjogxz 4409 16 76 76 CD cord-015369-72cjogxz 4409 17 ( ( -LRB- cord-015369-72cjogxz 4409 18 54 54 CD cord-015369-72cjogxz 4409 19 % % NN cord-015369-72cjogxz 4409 20 ) ) -RRB- cord-015369-72cjogxz 4410 1 thoracic thoracic JJ cord-015369-72cjogxz 4410 2 aortic aortic JJ cord-015369-72cjogxz 4410 3 aneurysms aneurysm NNS cord-015369-72cjogxz 4410 4 , , , cord-015369-72cjogxz 4410 5 63 63 CD cord-015369-72cjogxz 4410 6 ( ( -LRB- cord-015369-72cjogxz 4410 7 44 44 CD cord-015369-72cjogxz 4410 8 % % NN cord-015369-72cjogxz 4410 9 ) ) -RRB- cord-015369-72cjogxz 4410 10 thoracic thoracic JJ cord-015369-72cjogxz 4410 11 aortic aortic JJ cord-015369-72cjogxz 4410 12 dissections dissection NNS cord-015369-72cjogxz 4410 13 as as RB cord-015369-72cjogxz 4410 14 well well RB cord-015369-72cjogxz 4410 15 as as IN cord-015369-72cjogxz 4410 16 18 18 CD cord-015369-72cjogxz 4410 17 ( ( -LRB- cord-015369-72cjogxz 4410 18 13 13 CD cord-015369-72cjogxz 4410 19 % % NN cord-015369-72cjogxz 4410 20 ) ) -RRB- cord-015369-72cjogxz 4410 21 abdominal abdominal JJ cord-015369-72cjogxz 4410 22 aortic aortic JJ cord-015369-72cjogxz 4410 23 aneurysms aneurysm NNS cord-015369-72cjogxz 4410 24 . . . cord-015369-72cjogxz 4411 1 Mean mean JJ cord-015369-72cjogxz 4411 2 age age NN cord-015369-72cjogxz 4411 3 was be VBD cord-015369-72cjogxz 4411 4 57 57 CD cord-015369-72cjogxz 4411 5 AE AE NNP cord-015369-72cjogxz 4411 6 18 18 CD cord-015369-72cjogxz 4411 7 years year NNS cord-015369-72cjogxz 4411 8 . . . cord-015369-72cjogxz 4412 1 73 73 CD cord-015369-72cjogxz 4412 2 ( ( -LRB- cord-015369-72cjogxz 4412 3 51 51 CD cord-015369-72cjogxz 4412 4 % % NN cord-015369-72cjogxz 4412 5 ) ) -RRB- cord-015369-72cjogxz 4412 6 patients patient NNS cord-015369-72cjogxz 4412 7 were be VBD cord-015369-72cjogxz 4412 8 over over IN cord-015369-72cjogxz 4412 9 60 60 CD cord-015369-72cjogxz 4412 10 years year NNS cord-015369-72cjogxz 4412 11 of of IN cord-015369-72cjogxz 4412 12 age age NN cord-015369-72cjogxz 4412 13 and and CC cord-015369-72cjogxz 4412 14 19 19 CD cord-015369-72cjogxz 4412 15 ( ( -LRB- cord-015369-72cjogxz 4412 16 13 13 CD cord-015369-72cjogxz 4412 17 % % NN cord-015369-72cjogxz 4412 18 ) ) -RRB- cord-015369-72cjogxz 4413 1 patients patient NNS cord-015369-72cjogxz 4413 2 were be VBD cord-015369-72cjogxz 4413 3 over over IN cord-015369-72cjogxz 4413 4 75 75 CD cord-015369-72cjogxz 4413 5 years year NNS cord-015369-72cjogxz 4413 6 of of IN cord-015369-72cjogxz 4413 7 age age NN cord-015369-72cjogxz 4413 8 . . . cord-015369-72cjogxz 4414 1 Results result NNS cord-015369-72cjogxz 4414 2 . . . cord-015369-72cjogxz 4415 1 Medial medial JJ cord-015369-72cjogxz 4415 2 degeneration degeneration NN cord-015369-72cjogxz 4415 3 was be VBD cord-015369-72cjogxz 4415 4 diagnosed diagnose VBN cord-015369-72cjogxz 4415 5 in in IN cord-015369-72cjogxz 4415 6 94 94 CD cord-015369-72cjogxz 4415 7 ( ( -LRB- cord-015369-72cjogxz 4415 8 66 66 CD cord-015369-72cjogxz 4415 9 % % NN cord-015369-72cjogxz 4415 10 ) ) -RRB- cord-015369-72cjogxz 4415 11 patients patient NNS cord-015369-72cjogxz 4415 12 . . . cord-015369-72cjogxz 4416 1 Of of IN cord-015369-72cjogxz 4416 2 these these DT cord-015369-72cjogxz 4416 3 46 46 CD cord-015369-72cjogxz 4416 4 ( ( -LRB- cord-015369-72cjogxz 4416 5 61 61 CD cord-015369-72cjogxz 4416 6 % % NN cord-015369-72cjogxz 4416 7 ) ) -RRB- cord-015369-72cjogxz 4416 8 had have VBD cord-015369-72cjogxz 4416 9 thoracic thoracic JJ cord-015369-72cjogxz 4416 10 aortic aortic JJ cord-015369-72cjogxz 4416 11 aneurysms aneurysm NNS cord-015369-72cjogxz 4416 12 , , , cord-015369-72cjogxz 4416 13 37 37 CD cord-015369-72cjogxz 4416 14 ( ( -LRB- cord-015369-72cjogxz 4416 15 59 59 CD cord-015369-72cjogxz 4416 16 % % NN cord-015369-72cjogxz 4416 17 ) ) -RRB- cord-015369-72cjogxz 4417 1 thoracic thoracic JJ cord-015369-72cjogxz 4417 2 aortic aortic JJ cord-015369-72cjogxz 4417 3 dissections dissection NNS cord-015369-72cjogxz 4417 4 and and CC cord-015369-72cjogxz 4417 5 11 11 CD cord-015369-72cjogxz 4417 6 ( ( -LRB- cord-015369-72cjogxz 4417 7 61 61 CD cord-015369-72cjogxz 4417 8 % % NN cord-015369-72cjogxz 4417 9 ) ) -RRB- cord-015369-72cjogxz 4417 10 abdominal abdominal JJ cord-015369-72cjogxz 4417 11 aortic aortic JJ cord-015369-72cjogxz 4417 12 aneurysms aneurysm NNS cord-015369-72cjogxz 4417 13 . . . cord-015369-72cjogxz 4418 1 Severe severe JJ cord-015369-72cjogxz 4418 2 medial medial JJ cord-015369-72cjogxz 4418 3 degeneration degeneration NN cord-015369-72cjogxz 4418 4 was be VBD cord-015369-72cjogxz 4418 5 found find VBN cord-015369-72cjogxz 4418 6 in in IN cord-015369-72cjogxz 4418 7 24 24 CD cord-015369-72cjogxz 4418 8 ( ( -LRB- cord-015369-72cjogxz 4418 9 17 17 CD cord-015369-72cjogxz 4418 10 % % NN cord-015369-72cjogxz 4418 11 ) ) -RRB- cord-015369-72cjogxz 4418 12 patients patient NNS cord-015369-72cjogxz 4418 13 including include VBG cord-015369-72cjogxz 4418 14 8 8 CD cord-015369-72cjogxz 4418 15 ( ( -LRB- cord-015369-72cjogxz 4418 16 11 11 CD cord-015369-72cjogxz 4418 17 % % NN cord-015369-72cjogxz 4418 18 ) ) -RRB- cord-015369-72cjogxz 4418 19 thoracic thoracic JJ cord-015369-72cjogxz 4418 20 aortic aortic JJ cord-015369-72cjogxz 4418 21 aneurysms aneurysm NNS cord-015369-72cjogxz 4418 22 , , , cord-015369-72cjogxz 4418 23 9 9 CD cord-015369-72cjogxz 4418 24 ( ( -LRB- cord-015369-72cjogxz 4418 25 14 14 CD cord-015369-72cjogxz 4418 26 % % NN cord-015369-72cjogxz 4418 27 ) ) -RRB- cord-015369-72cjogxz 4418 28 thoracic thoracic JJ cord-015369-72cjogxz 4418 29 aortic aortic JJ cord-015369-72cjogxz 4418 30 dissections dissection NNS cord-015369-72cjogxz 4418 31 and and CC cord-015369-72cjogxz 4418 32 7 7 CD cord-015369-72cjogxz 4418 33 ( ( -LRB- cord-015369-72cjogxz 4418 34 39 39 CD cord-015369-72cjogxz 4418 35 % % NN cord-015369-72cjogxz 4418 36 ) ) -RRB- cord-015369-72cjogxz 4418 37 abdominal abdominal JJ cord-015369-72cjogxz 4418 38 aortic aortic JJ cord-015369-72cjogxz 4418 39 aneurysms aneurysm NNS cord-015369-72cjogxz 4418 40 ( ( -LRB- cord-015369-72cjogxz 4418 41 22 22 CD cord-015369-72cjogxz 4418 42 % % NN cord-015369-72cjogxz 4418 43 of of IN cord-015369-72cjogxz 4418 44 diagnoses diagnosis NNS cord-015369-72cjogxz 4418 45 in in IN cord-015369-72cjogxz 4418 46 patients patient NNS cord-015369-72cjogxz 4418 47 < < XX cord-015369-72cjogxz 4418 48 60 60 CD cord-015369-72cjogxz 4418 49 years year NNS cord-015369-72cjogxz 4418 50 of of IN cord-015369-72cjogxz 4418 51 age age NN cord-015369-72cjogxz 4418 52 vs. vs. CC cord-015369-72cjogxz 4418 53 36 36 CD cord-015369-72cjogxz 4418 54 % % NN cord-015369-72cjogxz 4418 55 of of IN cord-015369-72cjogxz 4418 56 diagnoses diagnosis NNS cord-015369-72cjogxz 4418 57 in in IN cord-015369-72cjogxz 4418 58 patient patient NN cord-015369-72cjogxz 4418 59 over over IN cord-015369-72cjogxz 4418 60 75 75 CD cord-015369-72cjogxz 4418 61 years year NNS cord-015369-72cjogxz 4418 62 of of IN cord-015369-72cjogxz 4418 63 age age NN cord-015369-72cjogxz 4418 64 ) ) -RRB- cord-015369-72cjogxz 4418 65 . . . cord-015369-72cjogxz 4419 1 Extensive extensive JJ cord-015369-72cjogxz 4419 2 arteriitis arteriitis NN cord-015369-72cjogxz 4419 3 was be VBD cord-015369-72cjogxz 4419 4 diagnosed diagnose VBN cord-015369-72cjogxz 4419 5 in in IN cord-015369-72cjogxz 4419 6 28 28 CD cord-015369-72cjogxz 4419 7 ( ( -LRB- cord-015369-72cjogxz 4419 8 20 20 CD cord-015369-72cjogxz 4419 9 % % NN cord-015369-72cjogxz 4419 10 ) ) -RRB- cord-015369-72cjogxz 4419 11 patients patient NNS cord-015369-72cjogxz 4419 12 including include VBG cord-015369-72cjogxz 4419 13 10 10 CD cord-015369-72cjogxz 4419 14 ( ( -LRB- cord-015369-72cjogxz 4419 15 13 13 CD cord-015369-72cjogxz 4419 16 % % NN cord-015369-72cjogxz 4419 17 ) ) -RRB- cord-015369-72cjogxz 4419 18 thoracic thoracic JJ cord-015369-72cjogxz 4419 19 aortic aortic JJ cord-015369-72cjogxz 4419 20 aneurysms aneurysm NNS cord-015369-72cjogxz 4419 21 , , , cord-015369-72cjogxz 4419 22 8 8 CD cord-015369-72cjogxz 4419 23 ( ( -LRB- cord-015369-72cjogxz 4419 24 13 13 CD cord-015369-72cjogxz 4419 25 % % NN cord-015369-72cjogxz 4419 26 ) ) -RRB- cord-015369-72cjogxz 4419 27 thoracic thoracic JJ cord-015369-72cjogxz 4419 28 aortic aortic JJ cord-015369-72cjogxz 4419 29 dissections dissection NNS cord-015369-72cjogxz 4419 30 and and CC cord-015369-72cjogxz 4419 31 10 10 CD cord-015369-72cjogxz 4419 32 ( ( -LRB- cord-015369-72cjogxz 4419 33 56 56 CD cord-015369-72cjogxz 4419 34 % % NN cord-015369-72cjogxz 4419 35 ) ) -RRB- cord-015369-72cjogxz 4419 36 abdominal abdominal JJ cord-015369-72cjogxz 4419 37 aortic aortic JJ cord-015369-72cjogxz 4419 38 aneurysms aneurysm NNS cord-015369-72cjogxz 4419 39 . . . cord-015369-72cjogxz 4420 1 Marfan Marfan NNP cord-015369-72cjogxz 4420 2 's 's POS cord-015369-72cjogxz 4420 3 syndrome syndrome NN cord-015369-72cjogxz 4420 4 was be VBD cord-015369-72cjogxz 4420 5 diagnosed diagnose VBN cord-015369-72cjogxz 4420 6 in in IN cord-015369-72cjogxz 4420 7 4 4 CD cord-015369-72cjogxz 4420 8 ( ( -LRB- cord-015369-72cjogxz 4420 9 3 3 CD cord-015369-72cjogxz 4420 10 % % NN cord-015369-72cjogxz 4420 11 ) ) -RRB- cord-015369-72cjogxz 4420 12 cases case NNS cord-015369-72cjogxz 4420 13 ( ( -LRB- cord-015369-72cjogxz 4420 14 3 3 CD cord-015369-72cjogxz 4420 15 thoracic thoracic JJ cord-015369-72cjogxz 4420 16 aortic aortic JJ cord-015369-72cjogxz 4420 17 aneurysms aneurysm NNS cord-015369-72cjogxz 4420 18 , , , cord-015369-72cjogxz 4420 19 1 1 CD cord-015369-72cjogxz 4420 20 thoracic thoracic JJ cord-015369-72cjogxz 4420 21 aortic aortic JJ cord-015369-72cjogxz 4420 22 dissection dissection NN cord-015369-72cjogxz 4420 23 ) ) -RRB- cord-015369-72cjogxz 4420 24 . . . cord-015369-72cjogxz 4421 1 Giant giant JJ cord-015369-72cjogxz 4421 2 cell cell NN cord-015369-72cjogxz 4421 3 arteriitis arteriitis NNP cord-015369-72cjogxz 4421 4 was be VBD cord-015369-72cjogxz 4421 5 found find VBN cord-015369-72cjogxz 4421 6 in in IN cord-015369-72cjogxz 4421 7 one one CD cord-015369-72cjogxz 4421 8 thoracoabdominal thoracoabdominal JJ cord-015369-72cjogxz 4421 9 aortic aortic JJ cord-015369-72cjogxz 4421 10 aneurysm aneurysm NN cord-015369-72cjogxz 4421 11 . . . cord-015369-72cjogxz 4422 1 Conclusions conclusion NNS cord-015369-72cjogxz 4422 2 . . . cord-015369-72cjogxz 4423 1 Medial medial JJ cord-015369-72cjogxz 4423 2 degeneration degeneration NN cord-015369-72cjogxz 4423 3 was be VBD cord-015369-72cjogxz 4423 4 the the DT cord-015369-72cjogxz 4423 5 most most RBS cord-015369-72cjogxz 4423 6 frequently frequently RB cord-015369-72cjogxz 4423 7 observed observe VBN cord-015369-72cjogxz 4423 8 histopathological histopathological JJ cord-015369-72cjogxz 4423 9 diagnosis diagnosis NN cord-015369-72cjogxz 4423 10 irrespective irrespective RB cord-015369-72cjogxz 4423 11 of of IN cord-015369-72cjogxz 4423 12 location location NN cord-015369-72cjogxz 4423 13 and and CC cord-015369-72cjogxz 4423 14 clinical clinical JJ cord-015369-72cjogxz 4423 15 presentation presentation NN cord-015369-72cjogxz 4423 16 . . . cord-015369-72cjogxz 4424 1 Aging age VBG cord-015369-72cjogxz 4424 2 is be VBZ cord-015369-72cjogxz 4424 3 associated associate VBN cord-015369-72cjogxz 4424 4 with with IN cord-015369-72cjogxz 4424 5 a a DT cord-015369-72cjogxz 4424 6 higher high JJR cord-015369-72cjogxz 4424 7 degree degree NN cord-015369-72cjogxz 4424 8 of of IN cord-015369-72cjogxz 4424 9 medial medial JJ cord-015369-72cjogxz 4424 10 degeneration degeneration NN cord-015369-72cjogxz 4424 11 as as RB cord-015369-72cjogxz 4424 12 well well RB cord-015369-72cjogxz 4424 13 as as IN cord-015369-72cjogxz 4424 14 with with IN cord-015369-72cjogxz 4424 15 a a DT cord-015369-72cjogxz 4424 16 higher high JJR cord-015369-72cjogxz 4424 17 percentage percentage NN cord-015369-72cjogxz 4424 18 of of IN cord-015369-72cjogxz 4424 19 inflammatory inflammatory JJ cord-015369-72cjogxz 4424 20 disease disease NN cord-015369-72cjogxz 4424 21 of of IN cord-015369-72cjogxz 4424 22 the the DT cord-015369-72cjogxz 4424 23 aortic aortic JJ cord-015369-72cjogxz 4424 24 wall wall NN cord-015369-72cjogxz 4424 25 . . . cord-015369-72cjogxz 4425 1 Österreichische Österreichische NNP cord-015369-72cjogxz 4425 2 Gesellschaft Gesellschaft NNP cord-015369-72cjogxz 4425 3 für für IN cord-015369-72cjogxz 4425 4 Adipositaschirurgie Adipositaschirurgie NNP cord-015369-72cjogxz 4425 5 : : : cord-015369-72cjogxz 4426 1 Chirurgie Chirurgie NNP cord-015369-72cjogxz 4426 2 der der NNP cord-015369-72cjogxz 4426 3 Adipositas Adipositas NNP cord-015369-72cjogxz 4426 4 und und NNP cord-015369-72cjogxz 4426 5 metabolischer metabolischer NNP cord-015369-72cjogxz 4427 1 Erkrankungen Erkrankungen NNP cord-015369-72cjogxz 4427 2 Teil Teil NNP cord-015369-72cjogxz 4427 3 2 2 CD cord-015369-72cjogxz 4427 4 448 448 CD cord-015369-72cjogxz 4427 5 Intermediate intermediate JJ cord-015369-72cjogxz 4427 6 weight weight NN cord-015369-72cjogxz 4427 7 loss loss NN cord-015369-72cjogxz 4427 8 after after IN cord-015369-72cjogxz 4427 9 sleeve sleeve NN cord-015369-72cjogxz 4427 10 gastrectomy gastrectomy NN cord-015369-72cjogxz 4427 11 S. S. NNP cord-015369-72cjogxz 4427 12 Ali Ali NNP cord-015369-72cjogxz 4427 13 - - HYPH cord-015369-72cjogxz 4427 14 Abdullah Abdullah NNP cord-015369-72cjogxz 4427 15 , , , cord-015369-72cjogxz 4427 16 M. M. NNP cord-015369-72cjogxz 4427 17 Schermann Schermann NNP cord-015369-72cjogxz 4427 18 , , , cord-015369-72cjogxz 4427 19 A. A. NNP cord-015369-72cjogxz 4427 20 Landsiedl Landsiedl NNP cord-015369-72cjogxz 4427 21 , , , cord-015369-72cjogxz 4427 22 S. S. NNP cord-015369-72cjogxz 4427 23 Kriwanek Kriwanek NNP cord-015369-72cjogxz 4427 24 Background Background NNP cord-015369-72cjogxz 4427 25 . . . cord-015369-72cjogxz 4428 1 The the DT cord-015369-72cjogxz 4428 2 long long JJ cord-015369-72cjogxz 4428 3 term term NN cord-015369-72cjogxz 4428 4 effects effect NNS cord-015369-72cjogxz 4428 5 of of IN cord-015369-72cjogxz 4428 6 sleeve sleeve NN cord-015369-72cjogxz 4428 7 gastrectomy gastrectomy NN cord-015369-72cjogxz 4428 8 have have VBP cord-015369-72cjogxz 4428 9 not not RB cord-015369-72cjogxz 4428 10 been be VBN cord-015369-72cjogxz 4428 11 described describe VBN cord-015369-72cjogxz 4428 12 to to IN cord-015369-72cjogxz 4428 13 the the DT cord-015369-72cjogxz 4428 14 present present JJ cord-015369-72cjogxz 4428 15 date date NN cord-015369-72cjogxz 4428 16 . . . cord-015369-72cjogxz 4429 1 Case Case NNP cord-015369-72cjogxz 4429 2 series series NN cord-015369-72cjogxz 4429 3 report report VBP cord-015369-72cjogxz 4429 4 significant significant JJ cord-015369-72cjogxz 4429 5 reoperation reoperation NN cord-015369-72cjogxz 4429 6 rates rate NNS cord-015369-72cjogxz 4429 7 due due JJ cord-015369-72cjogxz 4429 8 to to IN cord-015369-72cjogxz 4429 9 inadequate inadequate JJ cord-015369-72cjogxz 4429 10 weight weight NN cord-015369-72cjogxz 4429 11 loss loss NN cord-015369-72cjogxz 4429 12 , , , cord-015369-72cjogxz 4429 13 weight weight NN cord-015369-72cjogxz 4429 14 regain regain NN cord-015369-72cjogxz 4429 15 , , , cord-015369-72cjogxz 4429 16 or or CC cord-015369-72cjogxz 4429 17 gastro gastro JJ cord-015369-72cjogxz 4429 18 - - JJ cord-015369-72cjogxz 4429 19 esophageal esophageal JJ cord-015369-72cjogxz 4429 20 reflux reflux NN cord-015369-72cjogxz 4429 21 disorder disorder NN cord-015369-72cjogxz 4429 22 . . . cord-015369-72cjogxz 4430 1 The the DT cord-015369-72cjogxz 4430 2 aim aim NN cord-015369-72cjogxz 4430 3 of of IN cord-015369-72cjogxz 4430 4 our -PRON- PRP$ cord-015369-72cjogxz 4430 5 study study NN cord-015369-72cjogxz 4430 6 was be VBD cord-015369-72cjogxz 4430 7 to to TO cord-015369-72cjogxz 4430 8 analyze analyze VB cord-015369-72cjogxz 4430 9 intermediate intermediate JJ cord-015369-72cjogxz 4430 10 results result NNS cord-015369-72cjogxz 4430 11 3 3 CD cord-015369-72cjogxz 4430 12 to to TO cord-015369-72cjogxz 4430 13 5 5 CD cord-015369-72cjogxz 4430 14 years year NNS cord-015369-72cjogxz 4430 15 after after IN cord-015369-72cjogxz 4430 16 sleeve sleeve NN cord-015369-72cjogxz 4430 17 gastrectomy gastrectomy NN cord-015369-72cjogxz 4430 18 Methods method NNS cord-015369-72cjogxz 4430 19 and and CC cord-015369-72cjogxz 4430 20 results result NNS cord-015369-72cjogxz 4430 21 . . . cord-015369-72cjogxz 4431 1 Twenty twenty CD cord-015369-72cjogxz 4431 2 - - HYPH cord-015369-72cjogxz 4431 3 nine nine CD cord-015369-72cjogxz 4431 4 patients patient NNS cord-015369-72cjogxz 4431 5 ( ( -LRB- cord-015369-72cjogxz 4431 6 24 24 CD cord-015369-72cjogxz 4431 7 women woman NNS cord-015369-72cjogxz 4431 8 , , , cord-015369-72cjogxz 4431 9 5 5 CD cord-015369-72cjogxz 4431 10 men man NNS cord-015369-72cjogxz 4431 11 ) ) -RRB- cord-015369-72cjogxz 4431 12 were be VBD cord-015369-72cjogxz 4431 13 operated operate VBN cord-015369-72cjogxz 4431 14 between between IN cord-015369-72cjogxz 4431 15 2003 2003 CD cord-015369-72cjogxz 4431 16 or or CC cord-015369-72cjogxz 4431 17 2006 2006 CD cord-015369-72cjogxz 4431 18 . . . cord-015369-72cjogxz 4432 1 A a DT cord-015369-72cjogxz 4432 2 standardized standardized JJ cord-015369-72cjogxz 4432 3 procedure procedure NN cord-015369-72cjogxz 4432 4 was be VBD cord-015369-72cjogxz 4432 5 applied apply VBN cord-015369-72cjogxz 4432 6 . . . cord-015369-72cjogxz 4433 1 Calibration calibration NN cord-015369-72cjogxz 4433 2 of of IN cord-015369-72cjogxz 4433 3 the the DT cord-015369-72cjogxz 4433 4 sleeve sleeve NN cord-015369-72cjogxz 4433 5 was be VBD cord-015369-72cjogxz 4433 6 achieved achieve VBN cord-015369-72cjogxz 4433 7 with with IN cord-015369-72cjogxz 4433 8 a a DT cord-015369-72cjogxz 4433 9 33 33 CD cord-015369-72cjogxz 4433 10 F f NN cord-015369-72cjogxz 4433 11 bougie bougie FW cord-015369-72cjogxz 4433 12 . . . cord-015369-72cjogxz 4434 1 One one CD cord-015369-72cjogxz 4434 2 complication complication NN cord-015369-72cjogxz 4434 3 ( ( -LRB- cord-015369-72cjogxz 4434 4 staple staple JJ cord-015369-72cjogxz 4434 5 line line NN cord-015369-72cjogxz 4434 6 leak leak NN cord-015369-72cjogxz 4434 7 ) ) -RRB- cord-015369-72cjogxz 4434 8 occurred occur VBD cord-015369-72cjogxz 4434 9 and and CC cord-015369-72cjogxz 4434 10 was be VBD cord-015369-72cjogxz 4434 11 treated treat VBN cord-015369-72cjogxz 4434 12 by by IN cord-015369-72cjogxz 4434 13 a a DT cord-015369-72cjogxz 4434 14 reoperation reoperation NN cord-015369-72cjogxz 4434 15 . . . cord-015369-72cjogxz 4435 1 At at IN cord-015369-72cjogxz 4435 2 follow follow VB cord-015369-72cjogxz 4435 3 up up RP cord-015369-72cjogxz 4435 4 the the DT cord-015369-72cjogxz 4435 5 average average JJ cord-015369-72cjogxz 4435 6 excess excess JJ cord-015369-72cjogxz 4435 7 weight weight NN cord-015369-72cjogxz 4435 8 loss loss NN cord-015369-72cjogxz 4435 9 was be VBD cord-015369-72cjogxz 4435 10 65 65 CD cord-015369-72cjogxz 4435 11 percent percent NN cord-015369-72cjogxz 4435 12 . . . cord-015369-72cjogxz 4436 1 Six six CD cord-015369-72cjogxz 4436 2 patients patient NNS cord-015369-72cjogxz 4436 3 ( ( -LRB- cord-015369-72cjogxz 4436 4 20 20 CD cord-015369-72cjogxz 4436 5 % % NN cord-015369-72cjogxz 4436 6 ) ) -RRB- cord-015369-72cjogxz 4436 7 were be VBD cord-015369-72cjogxz 4436 8 converted convert VBN cord-015369-72cjogxz 4436 9 to to IN cord-015369-72cjogxz 4436 10 a a DT cord-015369-72cjogxz 4436 11 gastric gastric JJ cord-015369-72cjogxz 4436 12 bypass bypass NN cord-015369-72cjogxz 4436 13 in in IN cord-015369-72cjogxz 4436 14 3 3 CD cord-015369-72cjogxz 4436 15 cases case NNS cord-015369-72cjogxz 4436 16 due due JJ cord-015369-72cjogxz 4436 17 to to IN cord-015369-72cjogxz 4436 18 weight weight NN cord-015369-72cjogxz 4436 19 regain regain NN cord-015369-72cjogxz 4436 20 and and CC cord-015369-72cjogxz 4436 21 in in IN cord-015369-72cjogxz 4436 22 2 2 CD cord-015369-72cjogxz 4436 23 patients patient NNS cord-015369-72cjogxz 4436 24 because because IN cord-015369-72cjogxz 4436 25 of of IN cord-015369-72cjogxz 4436 26 reflux reflux NN cord-015369-72cjogxz 4436 27 problems problem NNS cord-015369-72cjogxz 4436 28 ( ( -LRB- cord-015369-72cjogxz 4436 29 2 2 CD cord-015369-72cjogxz 4436 30 ) ) -RRB- cord-015369-72cjogxz 4436 31 . . . cord-015369-72cjogxz 4437 1 One one CD cord-015369-72cjogxz 4437 2 patient patient NN cord-015369-72cjogxz 4437 3 was be VBD cord-015369-72cjogxz 4437 4 reoperated reoperate VBN cord-015369-72cjogxz 4437 5 after after IN cord-015369-72cjogxz 4437 6 a a DT cord-015369-72cjogxz 4437 7 first first JJ cord-015369-72cjogxz 4437 8 step step NN cord-015369-72cjogxz 4437 9 sleeve sleeve NN cord-015369-72cjogxz 4437 10 gastrectomy gastrectomy NN cord-015369-72cjogxz 4437 11 . . . cord-015369-72cjogxz 4438 1 Conclusions conclusion NNS cord-015369-72cjogxz 4438 2 . . . cord-015369-72cjogxz 4439 1 In in IN cord-015369-72cjogxz 4439 2 our -PRON- PRP$ cord-015369-72cjogxz 4439 3 experience experience NN cord-015369-72cjogxz 4439 4 sleeve sleeve NN cord-015369-72cjogxz 4439 5 gastrectomy gastrectomy NN cord-015369-72cjogxz 4439 6 seems seem VBZ cord-015369-72cjogxz 4439 7 to to TO cord-015369-72cjogxz 4439 8 be be VB cord-015369-72cjogxz 4439 9 an an DT cord-015369-72cjogxz 4439 10 effective effective JJ cord-015369-72cjogxz 4439 11 weight weight NN cord-015369-72cjogxz 4439 12 loss loss NN cord-015369-72cjogxz 4439 13 operation operation NN cord-015369-72cjogxz 4439 14 but but CC cord-015369-72cjogxz 4439 15 reoperation reoperation NN cord-015369-72cjogxz 4439 16 rates rate NNS cord-015369-72cjogxz 4439 17 are be VBP cord-015369-72cjogxz 4439 18 significantly significantly RB cord-015369-72cjogxz 4439 19 higher high JJR cord-015369-72cjogxz 4439 20 compard compard NN cord-015369-72cjogxz 4439 21 to to IN cord-015369-72cjogxz 4439 22 Roux Roux NNP cord-015369-72cjogxz 4439 23 Y Y NNP cord-015369-72cjogxz 4439 24 gastric gastric JJ cord-015369-72cjogxz 4439 25 bypass bypass NN cord-015369-72cjogxz 4439 26 . . . cord-015369-72cjogxz 4440 1 Background background NN cord-015369-72cjogxz 4440 2 . . . cord-015369-72cjogxz 4441 1 The the DT cord-015369-72cjogxz 4441 2 positive positive JJ cord-015369-72cjogxz 4441 3 long long JJ cord-015369-72cjogxz 4441 4 term term NN cord-015369-72cjogxz 4441 5 effects effect NNS cord-015369-72cjogxz 4441 6 of of IN cord-015369-72cjogxz 4441 7 bariatric bariatric JJ cord-015369-72cjogxz 4441 8 surgery surgery NN cord-015369-72cjogxz 4441 9 on on IN cord-015369-72cjogxz 4441 10 obesity obesity NN cord-015369-72cjogxz 4441 11 -associated -associated JJ cord-015369-72cjogxz 4441 12 comorbidities comorbiditie NNS cord-015369-72cjogxz 4441 13 and and CC cord-015369-72cjogxz 4441 14 survival survival NN cord-015369-72cjogxz 4441 15 depend depend VBP cord-015369-72cjogxz 4441 16 on on IN cord-015369-72cjogxz 4441 17 minimal minimal JJ cord-015369-72cjogxz 4441 18 postoperative postoperative JJ cord-015369-72cjogxz 4441 19 morbidity morbidity NN cord-015369-72cjogxz 4441 20 and and CC cord-015369-72cjogxz 4441 21 mortality mortality NN cord-015369-72cjogxz 4441 22 . . . cord-015369-72cjogxz 4442 1 Patient patient JJ cord-015369-72cjogxz 4442 2 safety safety NN cord-015369-72cjogxz 4442 3 has have VBZ cord-015369-72cjogxz 4442 4 therefore therefore RB cord-015369-72cjogxz 4442 5 , , , cord-015369-72cjogxz 4442 6 gained gain VBD cord-015369-72cjogxz 4442 7 a a DT cord-015369-72cjogxz 4442 8 high high JJ cord-015369-72cjogxz 4442 9 level level NN cord-015369-72cjogxz 4442 10 of of IN cord-015369-72cjogxz 4442 11 attention attention NN cord-015369-72cjogxz 4442 12 in in IN cord-015369-72cjogxz 4442 13 bariatric bariatric JJ cord-015369-72cjogxz 4442 14 surgery surgery NN cord-015369-72cjogxz 4442 15 in in IN cord-015369-72cjogxz 4442 16 the the DT cord-015369-72cjogxz 4442 17 last last JJ cord-015369-72cjogxz 4442 18 years year NNS cord-015369-72cjogxz 4442 19 . . . cord-015369-72cjogxz 4443 1 Methods method NNS cord-015369-72cjogxz 4443 2 and and CC cord-015369-72cjogxz 4443 3 results result NNS cord-015369-72cjogxz 4443 4 . . . cord-015369-72cjogxz 4444 1 Patient patient JJ cord-015369-72cjogxz 4444 2 safety safety NN cord-015369-72cjogxz 4444 3 is be VBZ cord-015369-72cjogxz 4444 4 increased increase VBN cord-015369-72cjogxz 4444 5 by by IN cord-015369-72cjogxz 4444 6 a a DT cord-015369-72cjogxz 4444 7 variety variety NN cord-015369-72cjogxz 4444 8 of of IN cord-015369-72cjogxz 4444 9 steps step NNS cord-015369-72cjogxz 4444 10 including include VBG cord-015369-72cjogxz 4444 11 correct correct JJ cord-015369-72cjogxz 4444 12 selection selection NN cord-015369-72cjogxz 4444 13 and and CC cord-015369-72cjogxz 4444 14 preparation preparation NN cord-015369-72cjogxz 4444 15 of of IN cord-015369-72cjogxz 4444 16 patients patient NNS cord-015369-72cjogxz 4444 17 , , , cord-015369-72cjogxz 4444 18 implementation implementation NN cord-015369-72cjogxz 4444 19 of of IN cord-015369-72cjogxz 4444 20 clinical clinical JJ cord-015369-72cjogxz 4444 21 pathways pathway NNS cord-015369-72cjogxz 4444 22 , , , cord-015369-72cjogxz 4444 23 application application NN cord-015369-72cjogxz 4444 24 of of IN cord-015369-72cjogxz 4444 25 a a DT cord-015369-72cjogxz 4444 26 universal universal JJ cord-015369-72cjogxz 4444 27 protocol protocol NN cord-015369-72cjogxz 4444 28 concerning concern VBG cord-015369-72cjogxz 4444 29 verification verification NN cord-015369-72cjogxz 4444 30 of of IN cord-015369-72cjogxz 4444 31 patients patient NNS cord-015369-72cjogxz 4444 32 and and CC cord-015369-72cjogxz 4444 33 procedures procedure NNS cord-015369-72cjogxz 4444 34 during during IN cord-015369-72cjogxz 4444 35 a a DT cord-015369-72cjogxz 4444 36 ' ' '' cord-015369-72cjogxz 4444 37 ' ' '' cord-015369-72cjogxz 4444 38 time time NN cord-015369-72cjogxz 4444 39 out out RP cord-015369-72cjogxz 4444 40 ' ' '' cord-015369-72cjogxz 4444 41 ' ' '' cord-015369-72cjogxz 4444 42 at at IN cord-015369-72cjogxz 4444 43 the the DT cord-015369-72cjogxz 4444 44 beginning beginning NN cord-015369-72cjogxz 4444 45 of of IN cord-015369-72cjogxz 4444 46 every every DT cord-015369-72cjogxz 4444 47 operation operation NN cord-015369-72cjogxz 4444 48 , , , cord-015369-72cjogxz 4444 49 structured structure VBN cord-015369-72cjogxz 4444 50 intra intra NNP cord-015369-72cjogxz 4444 51 - - HYPH cord-015369-72cjogxz 4444 52 und und JJ cord-015369-72cjogxz 4444 53 postoperative postoperative JJ cord-015369-72cjogxz 4444 54 communication communication NN cord-015369-72cjogxz 4444 55 ( ( -LRB- cord-015369-72cjogxz 4444 56 briefing briefing NN cord-015369-72cjogxz 4444 57 , , , cord-015369-72cjogxz 4444 58 debriefing debriefing NN cord-015369-72cjogxz 4444 59 ) ) -RRB- cord-015369-72cjogxz 4444 60 , , , cord-015369-72cjogxz 4444 61 high high JJ cord-015369-72cjogxz 4444 62 awareness awareness NN cord-015369-72cjogxz 4444 63 of of IN cord-015369-72cjogxz 4444 64 possible possible JJ cord-015369-72cjogxz 4444 65 complications complication NNS cord-015369-72cjogxz 4444 66 , , , cord-015369-72cjogxz 4444 67 guidelines guideline NNS cord-015369-72cjogxz 4444 68 for for IN cord-015369-72cjogxz 4444 69 the the DT cord-015369-72cjogxz 4444 70 diagnosis diagnosis NN cord-015369-72cjogxz 4444 71 and and CC cord-015369-72cjogxz 4444 72 treatment treatment NN cord-015369-72cjogxz 4444 73 of of IN cord-015369-72cjogxz 4444 74 complications complication NNS cord-015369-72cjogxz 4444 75 , , , cord-015369-72cjogxz 4444 76 standardized standardize VBN cord-015369-72cjogxz 4444 77 follow follow NN cord-015369-72cjogxz 4444 78 - - HYPH cord-015369-72cjogxz 4444 79 up up NN cord-015369-72cjogxz 4444 80 , , , cord-015369-72cjogxz 4444 81 and and CC cord-015369-72cjogxz 4444 82 systematic systematic JJ cord-015369-72cjogxz 4444 83 training training NN cord-015369-72cjogxz 4444 84 of of IN cord-015369-72cjogxz 4444 85 safety safety NN cord-015369-72cjogxz 4444 86 agenda agenda NN cord-015369-72cjogxz 4444 87 during during IN cord-015369-72cjogxz 4444 88 education education NN cord-015369-72cjogxz 4444 89 . . . cord-015369-72cjogxz 4445 1 Conclusions conclusion NNS cord-015369-72cjogxz 4445 2 . . . cord-015369-72cjogxz 4446 1 A a DT cord-015369-72cjogxz 4446 2 systematic systematic JJ cord-015369-72cjogxz 4446 3 approach approach NN cord-015369-72cjogxz 4446 4 to to TO cord-015369-72cjogxz 4446 5 ensure ensure VB cord-015369-72cjogxz 4446 6 optimal optimal JJ cord-015369-72cjogxz 4446 7 patient patient JJ cord-015369-72cjogxz 4446 8 safety safety NN cord-015369-72cjogxz 4446 9 is be VBZ cord-015369-72cjogxz 4446 10 mandatory mandatory JJ cord-015369-72cjogxz 4446 11 to to TO cord-015369-72cjogxz 4446 12 enable enable VB cord-015369-72cjogxz 4446 13 late late JJ cord-015369-72cjogxz 4446 14 benefits benefit NNS cord-015369-72cjogxz 4446 15 of of IN cord-015369-72cjogxz 4446 16 overweight overweight JJ cord-015369-72cjogxz 4446 17 surgery surgery NN cord-015369-72cjogxz 4446 18 . . . cord-015369-72cjogxz 4447 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4447 2 . . . cord-015369-72cjogxz 4448 1 In in IN cord-015369-72cjogxz 4448 2 der der NN cord-015369-72cjogxz 4448 3 Literatur Literatur NNP cord-015369-72cjogxz 4448 4 wird wird NNP cord-015369-72cjogxz 4448 5 die die VBP cord-015369-72cjogxz 4449 1 Wahrscheinlichkeit Wahrscheinlichkeit NNP cord-015369-72cjogxz 4449 2 einer einer NNP cord-015369-72cjogxz 4449 3 Bandmigration Bandmigration NNP cord-015369-72cjogxz 4449 4 nach nach NNP cord-015369-72cjogxz 4449 5 , , , cord-015369-72cjogxz 4449 6 , , , cord-015369-72cjogxz 4449 7 gastric gastric JJ cord-015369-72cjogxz 4449 8 banding banding NN cord-015369-72cjogxz 4449 9 ' ' '' cord-015369-72cjogxz 4450 1 ' ' `` cord-015369-72cjogxz 4450 2 mit mit NNP cord-015369-72cjogxz 4450 3 ca ca NNP cord-015369-72cjogxz 4450 4 . . . cord-015369-72cjogxz 4451 1 5 5 CD cord-015369-72cjogxz 4451 2 % % NN cord-015369-72cjogxz 4451 3 beschrieben beschrieben NNP cord-015369-72cjogxz 4451 4 . . . cord-015369-72cjogxz 4452 1 Praktisch Praktisch NNP cord-015369-72cjogxz 4452 2 immer immer NNP cord-015369-72cjogxz 4452 3 liegt liegt NNP cord-015369-72cjogxz 4452 4 eine eine NNP cord-015369-72cjogxz 4452 5 Bandinfektion Bandinfektion NNP cord-015369-72cjogxz 4452 6 zugrunde zugrunde NNP cord-015369-72cjogxz 4452 7 . . . cord-015369-72cjogxz 4453 1 Fall fall VB cord-015369-72cjogxz 4453 2 . . . cord-015369-72cjogxz 4454 1 Wir Wir NNP cord-015369-72cjogxz 4454 2 präsentieren präsentieren NNP cord-015369-72cjogxz 4454 3 eine eine NNP cord-015369-72cjogxz 4455 1 40 40 CD cord-015369-72cjogxz 4455 2 jährige jährige NNP cord-015369-72cjogxz 4455 3 Patientin Patientin NNP cord-015369-72cjogxz 4455 4 mit mit VBP cord-015369-72cjogxz 4455 5 einem einem NNP cord-015369-72cjogxz 4455 6 zu zu XX cord-015369-72cjogxz 4456 1 60 60 CD cord-015369-72cjogxz 4456 2 % % NN cord-015369-72cjogxz 4456 3 in in IN cord-015369-72cjogxz 4456 4 den den NNP cord-015369-72cjogxz 4456 5 Magen Magen NNP cord-015369-72cjogxz 4456 6 migrierten migrierten NNP cord-015369-72cjogxz 4456 7 Magenband Magenband NNP cord-015369-72cjogxz 4456 8 . . . cord-015369-72cjogxz 4457 1 Die die VB cord-015369-72cjogxz 4457 2 Indikation Indikation NNP cord-015369-72cjogxz 4458 1 zur zur NNP cord-015369-72cjogxz 4458 2 endoskopischen endoskopischen NNP cord-015369-72cjogxz 4458 3 Entfernung Entfernung NNP cord-015369-72cjogxz 4458 4 mittels mittels NNP cord-015369-72cjogxz 4458 5 Schneidedraht Schneidedraht NNP cord-015369-72cjogxz 4458 6 wurde wurde NN cord-015369-72cjogxz 4458 7 gestellt gestellt NNP cord-015369-72cjogxz 4458 8 . . . cord-015369-72cjogxz 4459 1 Hierbei Hierbei NNP cord-015369-72cjogxz 4459 2 wurde wurde NNP cord-015369-72cjogxz 4459 3 der der NNP cord-015369-72cjogxz 4459 4 Port Port NNP cord-015369-72cjogxz 4459 5 entfernt entfernt NNP cord-015369-72cjogxz 4459 6 , , , cord-015369-72cjogxz 4459 7 der der NNP cord-015369-72cjogxz 4459 8 Schlauch Schlauch NNP cord-015369-72cjogxz 4459 9 in in IN cord-015369-72cjogxz 4459 10 der der NNP cord-015369-72cjogxz 4459 11 freien freien NNP cord-015369-72cjogxz 4459 12 Bauchhöhle Bauchhöhle NNP cord-015369-72cjogxz 4459 13 versenkt versenkt NNP cord-015369-72cjogxz 4459 14 und und NNP cord-015369-72cjogxz 4459 15 anschließend anschließend NNP cord-015369-72cjogxz 4459 16 das das NNP cord-015369-72cjogxz 4459 17 Band Band NNP cord-015369-72cjogxz 4459 18 endoskopisch endoskopisch NNP cord-015369-72cjogxz 4459 19 mittels mittels NNP cord-015369-72cjogxz 4459 20 Schneidedraht Schneidedraht NNP cord-015369-72cjogxz 4459 21 ( ( -LRB- cord-015369-72cjogxz 4459 22 AMI AMI NNP cord-015369-72cjogxz 4459 23 ) ) -RRB- cord-015369-72cjogxz 4459 24 durchtrennt durchtrennt NNP cord-015369-72cjogxz 4459 25 . . . cord-015369-72cjogxz 4460 1 Während Während NNP cord-015369-72cjogxz 4460 2 der der NNP cord-015369-72cjogxz 4460 3 Versuche Versuche NNP cord-015369-72cjogxz 4460 4 , , , cord-015369-72cjogxz 4460 5 das das NNP cord-015369-72cjogxz 4460 6 impaktierte impaktierte NNP cord-015369-72cjogxz 4460 7 Band Band NNP cord-015369-72cjogxz 4460 8 endoskopisch endoskopisch NNP cord-015369-72cjogxz 4460 9 herauszuziehen herauszuziehen NNP cord-015369-72cjogxz 4460 10 , , , cord-015369-72cjogxz 4460 11 bemerkten bemerkten NNP cord-015369-72cjogxz 4460 12 wir wir NNP cord-015369-72cjogxz 4460 13 eine eine NNP cord-015369-72cjogxz 4460 14 massive massive NNP cord-015369-72cjogxz 4460 15 Auftreibung Auftreibung NNP cord-015369-72cjogxz 4460 16 des des NNP cord-015369-72cjogxz 4460 17 Abdomens Abdomens NNPS cord-015369-72cjogxz 4460 18 . . . cord-015369-72cjogxz 4461 1 Aufgrund Aufgrund NNP cord-015369-72cjogxz 4461 2 massiv massiv JJ cord-015369-72cjogxz 4461 3 freier freier NN cord-015369-72cjogxz 4461 4 Luft Luft NNP cord-015369-72cjogxz 4461 5 ( ( -LRB- cord-015369-72cjogxz 4461 6 Perforationsverdacht Perforationsverdacht NNP cord-015369-72cjogxz 4461 7 ) ) -RRB- cord-015369-72cjogxz 4461 8 wurde wurde NNP cord-015369-72cjogxz 4461 9 die die VBP cord-015369-72cjogxz 4462 1 Indikation Indikation NNP cord-015369-72cjogxz 4462 2 zur zur NNP cord-015369-72cjogxz 4462 3 Laparoskopie Laparoskopie NNP cord-015369-72cjogxz 4462 4 gestellt gestellt NNP cord-015369-72cjogxz 4462 5 . . . cord-015369-72cjogxz 4463 1 Nach Nach NNP cord-015369-72cjogxz 4463 2 Einbringen Einbringen NNP cord-015369-72cjogxz 4463 3 des des FW cord-015369-72cjogxz 4463 4 Optik Optik NNP cord-015369-72cjogxz 4464 1 -Trokars -trokar NNS cord-015369-72cjogxz 4465 1 imponierten imponierten NNP cord-015369-72cjogxz 4466 1 40 40 CD cord-015369-72cjogxz 4466 2 mm mm CD cord-015369-72cjogxz 4466 3 Hg Hg NNP cord-015369-72cjogxz 4466 4 Druck Druck NNP cord-015369-72cjogxz 4466 5 intraabdominell intraabdominell NN cord-015369-72cjogxz 4466 6 . . . cord-015369-72cjogxz 4467 1 Laparoskopisch Laparoskopisch NNP cord-015369-72cjogxz 4467 2 kein kein NNP cord-015369-72cjogxz 4467 3 Hinweis Hinweis NNP cord-015369-72cjogxz 4467 4 auf auf NNP cord-015369-72cjogxz 4467 5 Hohlorganperforation Hohlorganperforation NNP cord-015369-72cjogxz 4467 6 . . . cord-015369-72cjogxz 4468 1 Somit Somit NNP cord-015369-72cjogxz 4468 2 kann kann NNP cord-015369-72cjogxz 4468 3 man man NNP cord-015369-72cjogxz 4468 4 davon davon NNP cord-015369-72cjogxz 4468 5 ausgehen ausgehen NNP cord-015369-72cjogxz 4469 1 , , , cord-015369-72cjogxz 4469 2 dass dass NNP cord-015369-72cjogxz 4469 3 die die VBP cord-015369-72cjogxz 4470 1 Luft Luft NNP cord-015369-72cjogxz 4470 2 während während NNP cord-015369-72cjogxz 4470 3 der der NNP cord-015369-72cjogxz 4470 4 Gastroskopie Gastroskopie NNP cord-015369-72cjogxz 4470 5 über über FW cord-015369-72cjogxz 4470 6 das das NNP cord-015369-72cjogxz 4470 7 zuvor zuvor NNP cord-015369-72cjogxz 4470 8 durchtrennte durchtrennte NNP cord-015369-72cjogxz 4470 9 Schlauchsystem Schlauchsystem NNP cord-015369-72cjogxz 4470 10 in in IN cord-015369-72cjogxz 4470 11 den den NNP cord-015369-72cjogxz 4470 12 Bauchraum Bauchraum NNP cord-015369-72cjogxz 4470 13 gelangte gelangte NN cord-015369-72cjogxz 4470 14 . . . cord-015369-72cjogxz 4471 1 Die die VB cord-015369-72cjogxz 4471 2 Dauer Dauer NNP cord-015369-72cjogxz 4471 3 der der NN cord-015369-72cjogxz 4471 4 intraabdominellen intraabdominellen NN cord-015369-72cjogxz 4472 1 Druckerhöhung Druckerhöhung NNP cord-015369-72cjogxz 4472 2 betrug betrug NNP cord-015369-72cjogxz 4472 3 1 1 CD cord-015369-72cjogxz 4472 4 Stunde Stunde NNP cord-015369-72cjogxz 4472 5 . . . cord-015369-72cjogxz 4473 1 Postoperativ Postoperativ NNP cord-015369-72cjogxz 4473 2 kam kam NNP cord-015369-72cjogxz 4473 3 es es XX cord-015369-72cjogxz 4473 4 zu zu NNP cord-015369-72cjogxz 4473 5 einem einem NNP cord-015369-72cjogxz 4473 6 akuten akuten NNP cord-015369-72cjogxz 4473 7 Leberversagen Leberversagen NNP cord-015369-72cjogxz 4473 8 mit mit NNP cord-015369-72cjogxz 4473 9 massivem massivem NNP cord-015369-72cjogxz 4473 10 Transaminasenanstieg Transaminasenanstieg NNP cord-015369-72cjogxz 4474 1 ( ( -LRB- cord-015369-72cjogxz 4474 2 GOT get VBD cord-015369-72cjogxz 4474 3 > > XX cord-015369-72cjogxz 4475 1 11000 11000 CD cord-015369-72cjogxz 4475 2 , , , cord-015369-72cjogxz 4475 3 GPT GPT NNP cord-015369-72cjogxz 4476 1 > > XX cord-015369-72cjogxz 4477 1 13000 13000 CD cord-015369-72cjogxz 4477 2 , , , cord-015369-72cjogxz 4477 3 LDH LDH NNP cord-015369-72cjogxz 4477 4 > > XX cord-015369-72cjogxz 4477 5 7000 7000 CD cord-015369-72cjogxz 4477 6 ) ) -RRB- cord-015369-72cjogxz 4477 7 und und XX cord-015369-72cjogxz 4478 1 Abnahme Abnahme NNP cord-015369-72cjogxz 4478 2 der der NNP cord-015369-72cjogxz 4478 3 Lebersyntheseleistung Lebersyntheseleistung NNP cord-015369-72cjogxz 4478 4 ( ( -LRB- cord-015369-72cjogxz 4478 5 INR INR NNP cord-015369-72cjogxz 4478 6 bis bis NNP cord-015369-72cjogxz 4478 7 4,5 4,5 CD cord-015369-72cjogxz 4478 8 ) ) -RRB- cord-015369-72cjogxz 4478 9 , , , cord-015369-72cjogxz 4478 10 wohl wohl NNP cord-015369-72cjogxz 4478 11 infolge infolge NNP cord-015369-72cjogxz 4478 12 der der NNP cord-015369-72cjogxz 4478 13 druckbedingten druckbedingten NNP cord-015369-72cjogxz 4478 14 portalen portalen NNP cord-015369-72cjogxz 4478 15 Minderperfusion Minderperfusion NNP cord-015369-72cjogxz 4478 16 , , , cord-015369-72cjogxz 4478 17 jedoch jedoch NNP cord-015369-72cjogxz 4478 18 ohne ohne NNP cord-015369-72cjogxz 4478 19 Enzephalopathie Enzephalopathie NNP cord-015369-72cjogxz 4478 20 . . . cord-015369-72cjogxz 4479 1 Sonographisch Sonographisch NNP cord-015369-72cjogxz 4479 2 konnte konnte NNP cord-015369-72cjogxz 4479 3 eine eine NNP cord-015369-72cjogxz 4479 4 adäquate adäquate NNP cord-015369-72cjogxz 4479 5 Leberperfusion Leberperfusion NNP cord-015369-72cjogxz 4479 6 nachgewiesen nachgewiesen NNP cord-015369-72cjogxz 4480 1 werden werden NNP cord-015369-72cjogxz 4480 2 . . . cord-015369-72cjogxz 4481 1 Nach Nach NNP cord-015369-72cjogxz 4481 2 Peak Peak NNP cord-015369-72cjogxz 4481 3 am be VBP cord-015369-72cjogxz 4481 4 2 2 CD cord-015369-72cjogxz 4481 5 . . . cord-015369-72cjogxz 4482 1 postoperativen postoperativen NNP cord-015369-72cjogxz 4482 2 Tag Tag NNP cord-015369-72cjogxz 4482 3 waren waren NNP cord-015369-72cjogxz 4482 4 die die VBP cord-015369-72cjogxz 4482 5 Laborparameter Laborparameter NNP cord-015369-72cjogxz 4482 6 rückläufig rückläufig NN cord-015369-72cjogxz 4482 7 bis bis NNP cord-015369-72cjogxz 4482 8 zur zur NNP cord-015369-72cjogxz 4482 9 völligen völligen NNP cord-015369-72cjogxz 4482 10 Normalisierung Normalisierung NNP cord-015369-72cjogxz 4482 11 . . . cord-015369-72cjogxz 4483 1 I -PRON- PRP cord-015369-72cjogxz 4483 2 m be VBP cord-015369-72cjogxz 4483 3 Rahmen Rahmen NNP cord-015369-72cjogxz 4483 4 einer einer NNP cord-015369-72cjogxz 4483 5 exakten exakten NNP cord-015369-72cjogxz 4483 6 Leberdiagnostik Leberdiagnostik NNP cord-015369-72cjogxz 4483 7 konnte konnte NNP cord-015369-72cjogxz 4483 8 schließlich schließlich NNP cord-015369-72cjogxz 4483 9 eine eine NNP cord-015369-72cjogxz 4483 10 NASH NASH NNP cord-015369-72cjogxz 4483 11 diagnostiziert diagnostiziert NNP cord-015369-72cjogxz 4483 12 werden werden NNP cord-015369-72cjogxz 4483 13 . . . cord-015369-72cjogxz 4484 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4484 2 . . . cord-015369-72cjogxz 4485 1 Eine Eine NNP cord-015369-72cjogxz 4485 2 kurzzeitige kurzzeitige NNP cord-015369-72cjogxz 4485 3 portale portale NN cord-015369-72cjogxz 4485 4 Minderperfusion Minderperfusion NNP cord-015369-72cjogxz 4485 5 der der NNP cord-015369-72cjogxz 4485 6 Leber Leber NNP cord-015369-72cjogxz 4485 7 kann kann NNP cord-015369-72cjogxz 4485 8 bei bei NNP cord-015369-72cjogxz 4485 9 bereits bereits NNP cord-015369-72cjogxz 4486 1 vorgeschädigtem vorgeschädigtem NNP cord-015369-72cjogxz 4486 2 Organ Organ NNP cord-015369-72cjogxz 4486 3 ausreichen ausreichen NNP cord-015369-72cjogxz 4486 4 , , , cord-015369-72cjogxz 4486 5 um um UH cord-015369-72cjogxz 4486 6 zu zu NNP cord-015369-72cjogxz 4486 7 einem einem NNP cord-015369-72cjogxz 4486 8 Funktionsausfall Funktionsausfall NNP cord-015369-72cjogxz 4486 9 / / SYM cord-015369-72cjogxz 4486 10 akuten akuten VBN cord-015369-72cjogxz 4486 11 Leberversagen Leberversagen NNP cord-015369-72cjogxz 4486 12 zu zu NNP cord-015369-72cjogxz 4486 13 führen führen NNP cord-015369-72cjogxz 4486 14 . . . cord-015369-72cjogxz 4487 1 Um um UH cord-015369-72cjogxz 4487 2 so so RB cord-015369-72cjogxz 4487 3 eine eine JJ cord-015369-72cjogxz 4487 4 Situation situation NN cord-015369-72cjogxz 4487 5 in in IN cord-015369-72cjogxz 4487 6 Zukunft Zukunft NNP cord-015369-72cjogxz 4487 7 zu zu NNP cord-015369-72cjogxz 4487 8 vermeiden vermeiden NNP cord-015369-72cjogxz 4487 9 , , , cord-015369-72cjogxz 4487 10 haben haben NNP cord-015369-72cjogxz 4487 11 wir wir NNP cord-015369-72cjogxz 4487 12 be be NNP cord-015369-72cjogxz 4487 13 - - HYPH cord-015369-72cjogxz 4487 14 schlossen schlossen NNP cord-015369-72cjogxz 4487 15 , , , cord-015369-72cjogxz 4488 1 das das NNP cord-015369-72cjogxz 4488 2 Schlauchsystem Schlauchsystem NNP cord-015369-72cjogxz 4488 3 einzuknoten einzuknoten NNP cord-015369-72cjogxz 4488 4 , , , cord-015369-72cjogxz 4489 1 bevor bevor NNP cord-015369-72cjogxz 4489 2 es es NNP cord-015369-72cjogxz 4489 3 in in RP cord-015369-72cjogxz 4489 4 die die NN cord-015369-72cjogxz 4490 1 freie freie NNP cord-015369-72cjogxz 4490 2 Bauchhöhle Bauchhöhle NNP cord-015369-72cjogxz 4490 3 versenkt versenkt NNP cord-015369-72cjogxz 4490 4 wird wird NNP cord-015369-72cjogxz 4490 5 . . . cord-015369-72cjogxz 4490 6 _SP cord-015369-72cjogxz 4491 1 Background background NN cord-015369-72cjogxz 4491 2 . . . cord-015369-72cjogxz 4492 1 Due due IN cord-015369-72cjogxz 4492 2 to to IN cord-015369-72cjogxz 4492 3 the the DT cord-015369-72cjogxz 4492 4 rising rise VBG cord-015369-72cjogxz 4492 5 numbers number NNS cord-015369-72cjogxz 4492 6 of of IN cord-015369-72cjogxz 4492 7 obese obese JJ cord-015369-72cjogxz 4492 8 patients patient NNS cord-015369-72cjogxz 4492 9 treated treat VBN cord-015369-72cjogxz 4492 10 by by IN cord-015369-72cjogxz 4492 11 Roux roux NN cord-015369-72cjogxz 4492 12 - - HYPH cord-015369-72cjogxz 4492 13 en en NNP cord-015369-72cjogxz 4492 14 - - HYPH cord-015369-72cjogxz 4492 15 Y Y NNP cord-015369-72cjogxz 4492 16 bypass bypass VB cord-015369-72cjogxz 4492 17 the the DT cord-015369-72cjogxz 4492 18 problem problem NN cord-015369-72cjogxz 4492 19 of of IN cord-015369-72cjogxz 4492 20 choledocholithiasis choledocholithiasis NNP cord-015369-72cjogxz 4492 21 is be VBZ cord-015369-72cjogxz 4492 22 of of IN cord-015369-72cjogxz 4492 23 increasing increase VBG cord-015369-72cjogxz 4492 24 importance importance NN cord-015369-72cjogxz 4492 25 . . . cord-015369-72cjogxz 4493 1 For for IN cord-015369-72cjogxz 4493 2 anatomical anatomical JJ cord-015369-72cjogxz 4493 3 reasons reason NNS cord-015369-72cjogxz 4493 4 endoscopic endoscopic NNS cord-015369-72cjogxz 4493 5 access access NN cord-015369-72cjogxz 4493 6 to to IN cord-015369-72cjogxz 4493 7 the the DT cord-015369-72cjogxz 4493 8 bile bile NN cord-015369-72cjogxz 4493 9 tract tract NN cord-015369-72cjogxz 4493 10 may may MD cord-015369-72cjogxz 4493 11 prove prove VB cord-015369-72cjogxz 4493 12 difficult difficult JJ cord-015369-72cjogxz 4493 13 or or CC cord-015369-72cjogxz 4493 14 impossible impossible JJ cord-015369-72cjogxz 4493 15 . . . cord-015369-72cjogxz 4494 1 Methods method NNS cord-015369-72cjogxz 4494 2 and and CC cord-015369-72cjogxz 4494 3 results result NNS cord-015369-72cjogxz 4494 4 . . . cord-015369-72cjogxz 4495 1 Four four CD cord-015369-72cjogxz 4495 2 patients patient NNS cord-015369-72cjogxz 4495 3 who who WP cord-015369-72cjogxz 4495 4 presented present VBD cord-015369-72cjogxz 4495 5 symptoms symptom NNS cord-015369-72cjogxz 4495 6 of of IN cord-015369-72cjogxz 4495 7 choldeocholithiasis choldeocholithiasis NN cord-015369-72cjogxz 4495 8 after after IN cord-015369-72cjogxz 4495 9 Roux roux NN cord-015369-72cjogxz 4495 10 - - HYPH cord-015369-72cjogxz 4495 11 en en NNP cord-015369-72cjogxz 4495 12 - - HYPH cord-015369-72cjogxz 4495 13 y y NNP cord-015369-72cjogxz 4495 14 bypass bypass NN cord-015369-72cjogxz 4495 15 were be VBD cord-015369-72cjogxz 4495 16 successfully successfully RB cord-015369-72cjogxz 4495 17 treated treat VBN cord-015369-72cjogxz 4495 18 by by IN cord-015369-72cjogxz 4495 19 laparoscopy laparoscopy RB cord-015369-72cjogxz 4495 20 - - HYPH cord-015369-72cjogxz 4495 21 assisted assist VBN cord-015369-72cjogxz 4495 22 transgastric transgastric JJ cord-015369-72cjogxz 4495 23 ERCP ERCP NNP cord-015369-72cjogxz 4495 24 . . . cord-015369-72cjogxz 4496 1 In in IN cord-015369-72cjogxz 4496 2 2 2 CD cord-015369-72cjogxz 4496 3 cases case NNS cord-015369-72cjogxz 4496 4 this this DT cord-015369-72cjogxz 4496 5 procedure procedure NN cord-015369-72cjogxz 4496 6 was be VBD cord-015369-72cjogxz 4496 7 combined combine VBN cord-015369-72cjogxz 4496 8 with with IN cord-015369-72cjogxz 4496 9 a a DT cord-015369-72cjogxz 4496 10 laparoscopic laparoscopic JJ cord-015369-72cjogxz 4496 11 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 4496 12 . . . cord-015369-72cjogxz 4497 1 There there EX cord-015369-72cjogxz 4497 2 were be VBD cord-015369-72cjogxz 4497 3 no no DT cord-015369-72cjogxz 4497 4 complications complication NNS cord-015369-72cjogxz 4497 5 related relate VBN cord-015369-72cjogxz 4497 6 to to IN cord-015369-72cjogxz 4497 7 the the DT cord-015369-72cjogxz 4497 8 procedures procedure NNS cord-015369-72cjogxz 4497 9 . . . cord-015369-72cjogxz 4498 1 Conclusions conclusion NNS cord-015369-72cjogxz 4498 2 . . . cord-015369-72cjogxz 4499 1 In in IN cord-015369-72cjogxz 4499 2 our -PRON- PRP$ cord-015369-72cjogxz 4499 3 opinion opinion NN cord-015369-72cjogxz 4499 4 ' ' '' cord-015369-72cjogxz 4499 5 ' ' '' cord-015369-72cjogxz 4499 6 reversed reverse VBN cord-015369-72cjogxz 4499 7 - - HYPH cord-015369-72cjogxz 4499 8 NOTES note NNS cord-015369-72cjogxz 4499 9 ' ' POS cord-015369-72cjogxz 4499 10 ' ' '' cord-015369-72cjogxz 4499 11 is be VBZ cord-015369-72cjogxz 4499 12 a a DT cord-015369-72cjogxz 4499 13 safe safe JJ cord-015369-72cjogxz 4499 14 and and CC cord-015369-72cjogxz 4499 15 effective effective JJ cord-015369-72cjogxz 4499 16 way way NN cord-015369-72cjogxz 4499 17 of of IN cord-015369-72cjogxz 4499 18 treating treat VBG cord-015369-72cjogxz 4499 19 choledocholithiasis choledocholithiasis NN cord-015369-72cjogxz 4499 20 in in IN cord-015369-72cjogxz 4499 21 patients patient NNS cord-015369-72cjogxz 4499 22 after after IN cord-015369-72cjogxz 4499 23 Roux roux NN cord-015369-72cjogxz 4499 24 - - HYPH cord-015369-72cjogxz 4499 25 en en NNP cord-015369-72cjogxz 4499 26 - - HYPH cord-015369-72cjogxz 4499 27 y y NNP cord-015369-72cjogxz 4499 28 gastric gastric JJ cord-015369-72cjogxz 4499 29 bypass bypass NN cord-015369-72cjogxz 4499 30 . . . cord-015369-72cjogxz 4500 1 Korrekturoperationen Korrekturoperationen NNP cord-015369-72cjogxz 4500 2 nach nach NN cord-015369-72cjogxz 4500 3 erfolgloser erfolgloser NN cord-015369-72cjogxz 4500 4 Adipositaschirurgie Adipositaschirurgie NNP cord-015369-72cjogxz 4500 5 P. P. NNP cord-015369-72cjogxz 4500 6 Beckerhinn Beckerhinn NNP cord-015369-72cjogxz 4500 7 , , , cord-015369-72cjogxz 4500 8 S. S. NNP cord-015369-72cjogxz 4500 9 Schöppl Schöppl NNP cord-015369-72cjogxz 4500 10 , , , cord-015369-72cjogxz 4500 11 F. F. NNP cord-015369-72cjogxz 4500 12 Hoffer Hoffer NNP cord-015369-72cjogxz 4500 13 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4500 14 . . . cord-015369-72cjogxz 4501 1 Das Das NNP cord-015369-72cjogxz 4501 2 laparoskopisch laparoskopisch NNP cord-015369-72cjogxz 4502 1 implantierte implantierte NNP cord-015369-72cjogxz 4502 2 verstellbare verstellbare NNP cord-015369-72cjogxz 4502 3 Magenband Magenband NNP cord-015369-72cjogxz 4502 4 ( ( -LRB- cord-015369-72cjogxz 4502 5 AGB AGB NNP cord-015369-72cjogxz 4502 6 ) ) -RRB- cord-015369-72cjogxz 4503 1 ist ist NNP cord-015369-72cjogxz 4503 2 der der NNP cord-015369-72cjogxz 4503 3 häufigste häufigste NN cord-015369-72cjogxz 4503 4 bariatrische bariatrische NN cord-015369-72cjogxz 4503 5 Eingriff Eingriff NNP cord-015369-72cjogxz 4503 6 in in IN cord-015369-72cjogxz 4503 7 Europa Europa NNP cord-015369-72cjogxz 4503 8 . . . cord-015369-72cjogxz 4504 1 Langzeit Langzeit NNP cord-015369-72cjogxz 4504 2 - - HYPH cord-015369-72cjogxz 4504 3 Komplikationen Komplikationen NNP cord-015369-72cjogxz 4504 4 wie wie NNP cord-015369-72cjogxz 4504 5 Band Band NNP cord-015369-72cjogxz 4504 6 - - HYPH cord-015369-72cjogxz 4504 7 Slippage Slippage NNP cord-015369-72cjogxz 4504 8 , , , cord-015369-72cjogxz 4505 1 Pouch pouch NN cord-015369-72cjogxz 4505 2 - - HYPH cord-015369-72cjogxz 4505 3 oder oder NN cord-015369-72cjogxz 4505 4 Ö Ö NNP cord-015369-72cjogxz 4505 5 sophagus sophagus NNP cord-015369-72cjogxz 4505 6 - - HYPH cord-015369-72cjogxz 4505 7 Dilatationen Dilatationen NNP cord-015369-72cjogxz 4505 8 und und NNP cord-015369-72cjogxz 4505 9 mangelnder mangelnder NNP cord-015369-72cjogxz 4505 10 Gewichtsverlust Gewichtsverlust NNP cord-015369-72cjogxz 4505 11 erfordern erfordern JJ cord-015369-72cjogxz 4505 12 neuerliche neuerliche NN cord-015369-72cjogxz 4505 13 Operationen Operationen NNP cord-015369-72cjogxz 4505 14 . . . cord-015369-72cjogxz 4506 1 Die die VB cord-015369-72cjogxz 4506 2 offene offene NNP cord-015369-72cjogxz 4506 3 vertikale vertikale NNP cord-015369-72cjogxz 4507 1 Band band NN cord-015369-72cjogxz 4507 2 - - HYPH cord-015369-72cjogxz 4507 3 verstärkte verstärkte NNP cord-015369-72cjogxz 4507 4 Gastroplastik Gastroplastik NNP cord-015369-72cjogxz 4507 5 ( ( -LRB- cord-015369-72cjogxz 4507 6 VBG VBG NNP cord-015369-72cjogxz 4507 7 ) ) -RRB- cord-015369-72cjogxz 4507 8 war war NN cord-015369-72cjogxz 4508 1 eine eine NNP cord-015369-72cjogxz 4508 2 der der NNP cord-015369-72cjogxz 4508 3 beliebtesten beliebtesten NNP cord-015369-72cjogxz 4508 4 Adipositas Adipositas NNP cord-015369-72cjogxz 4508 5 - - HYPH cord-015369-72cjogxz 4508 6 Operationen Operationen NNP cord-015369-72cjogxz 4508 7 der der NN cord-015369-72cjogxz 4508 8 1980er 1980er JJ cord-015369-72cjogxz 4509 1 und und IN cord-015369-72cjogxz 4509 2 1990er 1990er JJ cord-015369-72cjogxz 4509 3 Jahre Jahre NNP cord-015369-72cjogxz 4509 4 . . . cord-015369-72cjogxz 4510 1 Klammernahtrupturen Klammernahtrupturen NNP cord-015369-72cjogxz 4510 2 führten führten NNP cord-015369-72cjogxz 4510 3 wegen wegen NNP cord-015369-72cjogxz 4510 4 neuerlicher neuerlicher NN cord-015369-72cjogxz 4510 5 Gewichtszunahme Gewichtszunahme NNP cord-015369-72cjogxz 4510 6 zu zu NNP cord-015369-72cjogxz 4510 7 Reinterventionen Reinterventionen NNP cord-015369-72cjogxz 4510 8 . . . cord-015369-72cjogxz 4511 1 Der Der NNP cord-015369-72cjogxz 4511 2 Magenbypass Magenbypass NNP cord-015369-72cjogxz 4511 3 ( ( -LRB- cord-015369-72cjogxz 4511 4 RYGBP RYGBP NNP cord-015369-72cjogxz 4511 5 ) ) -RRB- cord-015369-72cjogxz 4512 1 ist ist NNP cord-015369-72cjogxz 4512 2 der der NNP cord-015369-72cjogxz 4512 3 häufigste häufigste NN cord-015369-72cjogxz 4512 4 Eingriff Eingriff NNP cord-015369-72cjogxz 4512 5 nach nach NNP cord-015369-72cjogxz 4512 6 erfolglosen erfolglosen NNP cord-015369-72cjogxz 4512 7 bariatrischen bariatrischen NNP cord-015369-72cjogxz 4512 8 Operationen Operationen NNP cord-015369-72cjogxz 4512 9 . . . cord-015369-72cjogxz 4513 1 Wir Wir NNP cord-015369-72cjogxz 4513 2 untersuchten untersuchten NNP cord-015369-72cjogxz 4513 3 die die VBP cord-015369-72cjogxz 4513 4 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4513 5 nach nach NNP cord-015369-72cjogxz 4513 6 Korrektur Korrektur NNP cord-015369-72cjogxz 4513 7 - - HYPH cord-015369-72cjogxz 4513 8 Operationen Operationen NNP cord-015369-72cjogxz 4513 9 . . . cord-015369-72cjogxz 4514 1 Methodik Methodik NNP cord-015369-72cjogxz 4514 2 . . . cord-015369-72cjogxz 4515 1 Die die VB cord-015369-72cjogxz 4515 2 Daten Daten NNP cord-015369-72cjogxz 4515 3 aller aller FW cord-015369-72cjogxz 4515 4 Patienten Patienten NNP cord-015369-72cjogxz 4515 5 wurden wurden VBD cord-015369-72cjogxz 4515 6 prospektiv prospektiv JJ cord-015369-72cjogxz 4515 7 erfasst erfasst NNP cord-015369-72cjogxz 4515 8 . . . cord-015369-72cjogxz 4516 1 Die die VB cord-015369-72cjogxz 4516 2 postoperativen postoperativen NNP cord-015369-72cjogxz 4517 1 Veränderungen Veränderungen NNP cord-015369-72cjogxz 4517 2 bezü bezü NNP cord-015369-72cjogxz 4517 3 glich glich NNP cord-015369-72cjogxz 4517 4 Gewicht Gewicht NNP cord-015369-72cjogxz 4517 5 , , , cord-015369-72cjogxz 4517 6 Begleiterkrankungen Begleiterkrankungen NNP cord-015369-72cjogxz 4517 7 und und IN cord-015369-72cjogxz 4518 1 Lebensqualität Lebensqualität NNS cord-015369-72cjogxz 4518 2 wurden wurden VBD cord-015369-72cjogxz 4518 3 untersucht untersucht NNP cord-015369-72cjogxz 4518 4 . . . cord-015369-72cjogxz 4519 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4519 2 . . . cord-015369-72cjogxz 4520 1 Zwischen Zwischen NNP cord-015369-72cjogxz 4520 2 2004 2004 CD cord-015369-72cjogxz 4520 3 und und IN cord-015369-72cjogxz 4520 4 2008 2008 CD cord-015369-72cjogxz 4520 5 wurden wurden VBD cord-015369-72cjogxz 4520 6 75 75 CD cord-015369-72cjogxz 4520 7 Operationen Operationen NNP cord-015369-72cjogxz 4521 1 an an DT cord-015369-72cjogxz 4521 2 64 64 CD cord-015369-72cjogxz 4521 3 Frauen frauen NN cord-015369-72cjogxz 4521 4 und und IN cord-015369-72cjogxz 4521 5 10 10 CD cord-015369-72cjogxz 4521 6 Männern Männern NNP cord-015369-72cjogxz 4521 7 nach nach NNP cord-015369-72cjogxz 4521 8 erfolgloser erfolgloser NNP cord-015369-72cjogxz 4521 9 bariatrischer bariatrischer NNP cord-015369-72cjogxz 4521 10 Erst Erst NNP cord-015369-72cjogxz 4521 11 - - HYPH cord-015369-72cjogxz 4521 12 Operation Operation NNP cord-015369-72cjogxz 4521 13 durchgefü durchgefü NNP cord-015369-72cjogxz 4521 14 hrt hrt NNP cord-015369-72cjogxz 4521 15 . . . cord-015369-72cjogxz 4522 1 Das Das NNP cord-015369-72cjogxz 4522 2 Durchschnittsalter Durchschnittsalter NNP cord-015369-72cjogxz 4522 3 betrug betrug NNP cord-015369-72cjogxz 4522 4 zum zum NNP cord-015369-72cjogxz 4522 5 Zeitpunkt Zeitpunkt NNP cord-015369-72cjogxz 4522 6 der der NNP cord-015369-72cjogxz 4522 7 Operation Operation NNP cord-015369-72cjogxz 4523 1 41 41 CD cord-015369-72cjogxz 4523 2 Jahre Jahre NNP cord-015369-72cjogxz 4523 3 , , , cord-015369-72cjogxz 4523 4 der der NNP cord-015369-72cjogxz 4523 5 durchschnittliche durchschnittliche NNP cord-015369-72cjogxz 4523 6 BMI BMI NNP cord-015369-72cjogxz 4524 1 43 43 CD cord-015369-72cjogxz 4524 2 kg kg NNS cord-015369-72cjogxz 4524 3 / / SYM cord-015369-72cjogxz 4524 4 m m NN cord-015369-72cjogxz 4524 5 2 2 CD cord-015369-72cjogxz 4524 6 . . . cord-015369-72cjogxz 4525 1 Die die VB cord-015369-72cjogxz 4525 2 Erstoperationen Erstoperationen NNP cord-015369-72cjogxz 4525 3 waren waren NN cord-015369-72cjogxz 4525 4 in in IN cord-015369-72cjogxz 4525 5 59 59 CD cord-015369-72cjogxz 4525 6 Fällen Fällen NNP cord-015369-72cjogxz 4525 7 ein ein NNP cord-015369-72cjogxz 4525 8 AGB AGB NNP cord-015369-72cjogxz 4525 9 , , , cord-015369-72cjogxz 4525 10 9 9 CD cord-015369-72cjogxz 4525 11 mal mal FW cord-015369-72cjogxz 4525 12 ein ein FW cord-015369-72cjogxz 4525 13 VBG VBG NNP cord-015369-72cjogxz 4525 14 , , , cord-015369-72cjogxz 4525 15 5 5 CD cord-015369-72cjogxz 4525 16 Sleeve Sleeve NNP cord-015369-72cjogxz 4525 17 - - HYPH cord-015369-72cjogxz 4525 18 Gastrektomien Gastrektomien NNP cord-015369-72cjogxz 4525 19 und und IN cord-015369-72cjogxz 4525 20 ein ein NNP cord-015369-72cjogxz 4525 21 Magenschrittmacher Magenschrittmacher NNP cord-015369-72cjogxz 4525 22 . . . cord-015369-72cjogxz 4526 1 Dreimal Dreimal NNP cord-015369-72cjogxz 4526 2 war war NN cord-015369-72cjogxz 4526 3 das das NNP cord-015369-72cjogxz 4526 4 Band Band NNP cord-015369-72cjogxz 4526 5 bereits bereits NNP cord-015369-72cjogxz 4527 1 vor vor NNP cord-015369-72cjogxz 4527 2 der der NNP cord-015369-72cjogxz 4527 3 Korrekturoperation Korrekturoperation NNP cord-015369-72cjogxz 4527 4 entfernt entfernt NNP cord-015369-72cjogxz 4527 5 worden worden NNP cord-015369-72cjogxz 4527 6 . . . cord-015369-72cjogxz 4528 1 55 55 CD cord-015369-72cjogxz 4528 2 Revisionseingriffe Revisionseingriffe NNP cord-015369-72cjogxz 4528 3 wurden wurden NNP cord-015369-72cjogxz 4528 4 laparoskopisch laparoskopisch NNP cord-015369-72cjogxz 4528 5 begonnen begonnen NNP cord-015369-72cjogxz 4528 6 , , , cord-015369-72cjogxz 4528 7 zweimal zweimal NNP cord-015369-72cjogxz 4528 8 musste musste NNP cord-015369-72cjogxz 4528 9 konvertiert konvertiert NNP cord-015369-72cjogxz 4528 10 werden werden NNP cord-015369-72cjogxz 4528 11 . . . cord-015369-72cjogxz 4529 1 45 45 CD cord-015369-72cjogxz 4529 2 mal mal JJ cord-015369-72cjogxz 4529 3 wurde wurde NN cord-015369-72cjogxz 4529 4 nach nach NNP cord-015369-72cjogxz 4529 5 Entfernung Entfernung NNP cord-015369-72cjogxz 4529 6 des des FW cord-015369-72cjogxz 4529 7 Magenbandes Magenbandes NNP cord-015369-72cjogxz 4529 8 in in IN cord-015369-72cjogxz 4529 9 der der NNP cord-015369-72cjogxz 4529 10 selben selben NNP cord-015369-72cjogxz 4530 1 Sitzung Sitzung NNP cord-015369-72cjogxz 4530 2 ein ein NNP cord-015369-72cjogxz 4530 3 RYGBP RYGBP NNP cord-015369-72cjogxz 4530 4 angelegt angelegt RB cord-015369-72cjogxz 4530 5 . . . cord-015369-72cjogxz 4531 1 8 8 CD cord-015369-72cjogxz 4531 2 laparoskopische laparoskopische NNP cord-015369-72cjogxz 4531 3 Sleeve Sleeve NNP cord-015369-72cjogxz 4531 4 - - HYPH cord-015369-72cjogxz 4531 5 Gastrektomien Gastrektomien NNP cord-015369-72cjogxz 4531 6 wurden wurden NNP cord-015369-72cjogxz 4531 7 durchgefü durchgefü NNP cord-015369-72cjogxz 4531 8 hrt hrt NNP cord-015369-72cjogxz 4531 9 , , , cord-015369-72cjogxz 4531 10 dreimal dreimal NNP cord-015369-72cjogxz 4531 11 wurde wurde NNP cord-015369-72cjogxz 4531 12 ein ein NNP cord-015369-72cjogxz 4531 13 neues neues NNP cord-015369-72cjogxz 4531 14 SAGB SAGB NNP cord-015369-72cjogxz 4531 15 eingebracht eingebracht NN cord-015369-72cjogxz 4531 16 , , , cord-015369-72cjogxz 4531 17 drei drei NNP cord-015369-72cjogxz 4531 18 Bänder Bänder NNP cord-015369-72cjogxz 4531 19 konnten konnten NNP cord-015369-72cjogxz 4531 20 repositioniert repositioniert NNP cord-015369-72cjogxz 4531 21 werden werden NNP cord-015369-72cjogxz 4531 22 . . . cord-015369-72cjogxz 4532 1 Revisionspflichtige Revisionspflichtige NNP cord-015369-72cjogxz 4532 2 Komplikationen Komplikationen NNP cord-015369-72cjogxz 4532 3 beobachteten beobachteten IN cord-015369-72cjogxz 4532 4 wir wir NNP cord-015369-72cjogxz 4532 5 bei bei NNP cord-015369-72cjogxz 4532 6 9 9 CD cord-015369-72cjogxz 4532 7 Patienten Patienten NNP cord-015369-72cjogxz 4532 8 ( ( -LRB- cord-015369-72cjogxz 4532 9 13 13 CD cord-015369-72cjogxz 4532 10 % % NN cord-015369-72cjogxz 4532 11 ) ) -RRB- cord-015369-72cjogxz 4532 12 ( ( -LRB- cord-015369-72cjogxz 4532 13 2 2 CD cord-015369-72cjogxz 4532 14 Blutungen Blutungen NNP cord-015369-72cjogxz 4532 15 , , , cord-015369-72cjogxz 4532 16 2 2 CD cord-015369-72cjogxz 4532 17 Trokarhernien Trokarhernien NNP cord-015369-72cjogxz 4532 18 , , , cord-015369-72cjogxz 4532 19 2 2 CD cord-015369-72cjogxz 4532 20 innere innere NNP cord-015369-72cjogxz 4532 21 Hernien Hernien NNP cord-015369-72cjogxz 4532 22 , , , cord-015369-72cjogxz 4532 23 3 3 CD cord-015369-72cjogxz 4532 24 andere andere NN cord-015369-72cjogxz 4532 25 ) ) -RRB- cord-015369-72cjogxz 4532 26 . . . cord-015369-72cjogxz 4533 1 Keine Keine NNP cord-015369-72cjogxz 4533 2 Leckagen Leckagen NNP cord-015369-72cjogxz 4533 3 oder oder NNP cord-015369-72cjogxz 4533 4 Todesfälle Todesfälle NNP cord-015369-72cjogxz 4533 5 traten traten NNP cord-015369-72cjogxz 4533 6 in in IN cord-015369-72cjogxz 4533 7 dieser dieser NNP cord-015369-72cjogxz 4533 8 Serie Serie NNP cord-015369-72cjogxz 4533 9 auf auf NNP cord-015369-72cjogxz 4533 10 . . . cord-015369-72cjogxz 4534 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4534 2 . . . cord-015369-72cjogxz 4535 1 Korrektureingriffe Korrektureingriffe NNP cord-015369-72cjogxz 4535 2 nach nach NN cord-015369-72cjogxz 4535 3 erfolgloser erfolgloser NN cord-015369-72cjogxz 4535 4 Adipositas Adipositas NNP cord-015369-72cjogxz 4535 5 - - HYPH cord-015369-72cjogxz 4535 6 Operation Operation NNP cord-015369-72cjogxz 4535 7 haben haben VBP cord-015369-72cjogxz 4535 8 eine eine NNP cord-015369-72cjogxz 4535 9 höhere höhere FW cord-015369-72cjogxz 4535 10 Komplikationsrate Komplikationsrate NNP cord-015369-72cjogxz 4535 11 als als NNP cord-015369-72cjogxz 4535 12 Erstoperationen Erstoperationen NNP cord-015369-72cjogxz 4535 13 . . . cord-015369-72cjogxz 4536 1 Die die VB cord-015369-72cjogxz 4536 2 guten guten NNP cord-015369-72cjogxz 4536 3 Erfolge Erfolge NNP cord-015369-72cjogxz 4536 4 in in IN cord-015369-72cjogxz 4536 5 Bezug Bezug NNP cord-015369-72cjogxz 4536 6 auf auf NNP cord-015369-72cjogxz 4536 7 die die VBP cord-015369-72cjogxz 4536 8 Gewichtsreduktion Gewichtsreduktion NNP cord-015369-72cjogxz 4536 9 , , , cord-015369-72cjogxz 4536 10 die die VB cord-015369-72cjogxz 4537 1 Verbesserung Verbesserung NNP cord-015369-72cjogxz 4537 2 der der XX cord-015369-72cjogxz 4537 3 assoziierten assoziierten NNP cord-015369-72cjogxz 4537 4 Erkrankungen Erkrankungen NNP cord-015369-72cjogxz 4538 1 und und NNP cord-015369-72cjogxz 4538 2 die die VB cord-015369-72cjogxz 4539 1 Lebensqualität Lebensqualität NNS cord-015369-72cjogxz 4539 2 rechtfertigen rechtfertigen VBP cord-015369-72cjogxz 4539 3 das das NNP cord-015369-72cjogxz 4539 4 etwas etwas NNP cord-015369-72cjogxz 4539 5 erhöhte erhöhte NNP cord-015369-72cjogxz 4539 6 Risiko Risiko NNP cord-015369-72cjogxz 4539 7 . . . cord-015369-72cjogxz 4540 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4540 2 . . . cord-015369-72cjogxz 4541 1 Rund Rund NNP cord-015369-72cjogxz 4541 2 80.000 80.000 CD cord-015369-72cjogxz 4542 1 Ö Ö NNP cord-015369-72cjogxz 4542 2 sterreicherInnen sterreicherInnen NNP cord-015369-72cjogxz 4542 3 leiden leiden NNP cord-015369-72cjogxz 4543 1 unter unter NNP cord-015369-72cjogxz 4543 2 einer einer NNP cord-015369-72cjogxz 4543 3 Adipositas Adipositas NNP cord-015369-72cjogxz 4543 4 permagna permagna NNP cord-015369-72cjogxz 4544 1 ( ( -LRB- cord-015369-72cjogxz 4544 2 Grad Grad NNP cord-015369-72cjogxz 4544 3 III III NNP cord-015369-72cjogxz 4544 4 ) ) -RRB- cord-015369-72cjogxz 4545 1 mit mit NNP cord-015369-72cjogxz 4545 2 einem einem NNP cord-015369-72cjogxz 4545 3 BMI BMI NNP cord-015369-72cjogxz 4545 4 > > XX cord-015369-72cjogxz 4545 5 40 40 CD cord-015369-72cjogxz 4545 6 bei bei NNP cord-015369-72cjogxz 4545 7 steigender steigender NNP cord-015369-72cjogxz 4545 8 Tendenz Tendenz NNP cord-015369-72cjogxz 4545 9 . . . cord-015369-72cjogxz 4546 1 Entsprechend Entsprechend NNP cord-015369-72cjogxz 4546 2 nimmt nimmt NNP cord-015369-72cjogxz 4546 3 die die VBP cord-015369-72cjogxz 4546 4 Anzahl Anzahl NNP cord-015369-72cjogxz 4546 5 der der NNP cord-015369-72cjogxz 4546 6 bariatrischen bariatrischen NNP cord-015369-72cjogxz 4546 7 Operationen Operationen NNP cord-015369-72cjogxz 4546 8 und und IN cord-015369-72cjogxz 4546 9 in in IN cord-015369-72cjogxz 4546 10 weiterer weiterer NNP cord-015369-72cjogxz 4546 11 Folge Folge NNP cord-015369-72cjogxz 4546 12 die die VBP cord-015369-72cjogxz 4546 13 Notwendigkeit Notwendigkeit NNP cord-015369-72cjogxz 4546 14 von von NNP cord-015369-72cjogxz 4546 15 konturverbessernden konturverbessernden VBN cord-015369-72cjogxz 4546 16 Operationen Operationen NNP cord-015369-72cjogxz 4546 17 zu zu NNP cord-015369-72cjogxz 4546 18 . . . cord-015369-72cjogxz 4547 1 Das Das NNP cord-015369-72cjogxz 4547 2 untere untere NNP cord-015369-72cjogxz 4547 3 bzw bzw NNP cord-015369-72cjogxz 4547 4 . . . cord-015369-72cjogxz 4548 1 das das NNP cord-015369-72cjogxz 4548 2 obere obere NNP cord-015369-72cjogxz 4548 3 Bodylift Bodylift NNP cord-015369-72cjogxz 4548 4 bieten bieten NNP cord-015369-72cjogxz 4548 5 die die VBP cord-015369-72cjogxz 4548 6 Möglichkeit Möglichkeit NNP cord-015369-72cjogxz 4548 7 einer einer NNP cord-015369-72cjogxz 4549 1 Straffung Straffung NNP cord-015369-72cjogxz 4549 2 von von NNP cord-015369-72cjogxz 4549 3 Abdomen Abdomen NNP cord-015369-72cjogxz 4549 4 , , , cord-015369-72cjogxz 4549 5 Oberschenkel Oberschenkel NNP cord-015369-72cjogxz 4549 6 , , , cord-015369-72cjogxz 4549 7 Hü Hü NNP cord-015369-72cjogxz 4549 8 fte fte NN cord-015369-72cjogxz 4549 9 , , , cord-015369-72cjogxz 4549 10 Gesäß Gesäß NNP cord-015369-72cjogxz 4550 1 und und NNP cord-015369-72cjogxz 4551 1 Rü Rü NNP cord-015369-72cjogxz 4551 2 cken cken JJ cord-015369-72cjogxz 4551 3 bzw bzw NNP cord-015369-72cjogxz 4551 4 . . . cord-015369-72cjogxz 4552 1 von von NNP cord-015369-72cjogxz 4552 2 oberem oberem NNP cord-015369-72cjogxz 4552 3 Rumpf Rumpf NNP cord-015369-72cjogxz 4552 4 , , , cord-015369-72cjogxz 4552 5 der der NNP cord-015369-72cjogxz 4552 6 Brü Brü NNP cord-015369-72cjogxz 4552 7 ste ste NNP cord-015369-72cjogxz 4552 8 und und IN cord-015369-72cjogxz 4552 9 der der NNP cord-015369-72cjogxz 4552 10 Oberarme Oberarme NNP cord-015369-72cjogxz 4552 11 in in IN cord-015369-72cjogxz 4552 12 einer einer NNP cord-015369-72cjogxz 4552 13 Sitzung Sitzung NNP cord-015369-72cjogxz 4552 14 . . . cord-015369-72cjogxz 4553 1 Methodik Methodik NNP cord-015369-72cjogxz 4553 2 . . . cord-015369-72cjogxz 4554 1 Anhand Anhand NNP cord-015369-72cjogxz 4554 2 von von NNP cord-015369-72cjogxz 4554 3 Fallbeispielen Fallbeispielen NNP cord-015369-72cjogxz 4554 4 werden werden NNP cord-015369-72cjogxz 4554 5 das das NNP cord-015369-72cjogxz 4554 6 perioperative perioperative NNP cord-015369-72cjogxz 4554 7 Management Management NNP cord-015369-72cjogxz 4555 1 und und NNP cord-015369-72cjogxz 4555 2 die die VB cord-015369-72cjogxz 4556 1 einzelnen einzelnen NNP cord-015369-72cjogxz 4556 2 Operationsschritte Operationsschritte NNP cord-015369-72cjogxz 4556 3 eines eines NNPS cord-015369-72cjogxz 4557 1 unteren unteren NNP cord-015369-72cjogxz 4557 2 Bodylifts Bodylifts NNP cord-015369-72cjogxz 4557 3 in in IN cord-015369-72cjogxz 4557 4 der der NNP cord-015369-72cjogxz 4557 5 modifizierten modifizierten NNP cord-015369-72cjogxz 4557 6 Technik Technik NNP cord-015369-72cjogxz 4557 7 nach nach NN cord-015369-72cjogxz 4557 8 Ted Ted NNP cord-015369-72cjogxz 4557 9 Lockwood Lockwood NNP cord-015369-72cjogxz 4557 10 bzw bzw NNP cord-015369-72cjogxz 4557 11 . . . cord-015369-72cjogxz 4558 1 eines eines NNP cord-015369-72cjogxz 4558 2 oberen oberen NNP cord-015369-72cjogxz 4558 3 Bodylifts Bodylifts NNP cord-015369-72cjogxz 4558 4 in in IN cord-015369-72cjogxz 4558 5 der der NNP cord-015369-72cjogxz 4558 6 Technik Technik NNP cord-015369-72cjogxz 4558 7 nach nach NNP cord-015369-72cjogxz 4558 8 Al Al NNP cord-015369-72cjogxz 4558 9 Aly Aly NNP cord-015369-72cjogxz 4558 10 vorgestellt vorgestellt NNP cord-015369-72cjogxz 4558 11 . . . cord-015369-72cjogxz 4559 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4559 2 . . . cord-015369-72cjogxz 4560 1 Bei Bei NNP cord-015369-72cjogxz 4560 2 allen allen NNP cord-015369-72cjogxz 4560 3 Patienten Patienten NNP cord-015369-72cjogxz 4560 4 konnte konnte NNP cord-015369-72cjogxz 4561 1 eine eine NNP cord-015369-72cjogxz 4561 2 deutliche deutliche NNP cord-015369-72cjogxz 4561 3 Verbesserung Verbesserung NNP cord-015369-72cjogxz 4561 4 der der NNP cord-015369-72cjogxz 4561 5 Körperkontur Körperkontur NNP cord-015369-72cjogxz 4561 6 erreicht erreicht NN cord-015369-72cjogxz 4561 7 werden werden NNP cord-015369-72cjogxz 4561 8 . . . cord-015369-72cjogxz 4562 1 Schwerwiegende Schwerwiegende NNP cord-015369-72cjogxz 4562 2 Komplikationen Komplikationen NNP cord-015369-72cjogxz 4562 3 ( ( -LRB- cord-015369-72cjogxz 4562 4 Thrombose Thrombose NNP cord-015369-72cjogxz 4562 5 , , , cord-015369-72cjogxz 4562 6 Pulmonalembolie Pulmonalembolie NNP cord-015369-72cjogxz 4562 7 ) ) -RRB- cord-015369-72cjogxz 4562 8 traten traten NNP cord-015369-72cjogxz 4562 9 nicht nicht NNP cord-015369-72cjogxz 4562 10 auf auf NNP cord-015369-72cjogxz 4562 11 . . . cord-015369-72cjogxz 4563 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4563 2 . . . cord-015369-72cjogxz 4564 1 Das Das NNP cord-015369-72cjogxz 4564 2 Bodylift Bodylift NNP cord-015369-72cjogxz 4564 3 ermöglicht ermöglicht NNP cord-015369-72cjogxz 4564 4 das das NNP cord-015369-72cjogxz 4564 5 gleichzeitige gleichzeitige NNP cord-015369-72cjogxz 4565 1 Straffen Straffen NNP cord-015369-72cjogxz 4565 2 von von NNP cord-015369-72cjogxz 4565 3 mehreren mehreren NNP cord-015369-72cjogxz 4565 4 Körperarealen Körperarealen NNP cord-015369-72cjogxz 4565 5 mit mit NNP cord-015369-72cjogxz 4565 6 fließenden fließenden VBD cord-015369-72cjogxz 4565 7 Konturübergängen Konturübergängen NNP cord-015369-72cjogxz 4565 8 in in IN cord-015369-72cjogxz 4565 9 einer einer NNP cord-015369-72cjogxz 4565 10 Sitzung Sitzung NNP cord-015369-72cjogxz 4565 11 . . . cord-015369-72cjogxz 4566 1 Dies die VBZ cord-015369-72cjogxz 4566 2 führt führt NNP cord-015369-72cjogxz 4566 3 nicht nicht NNP cord-015369-72cjogxz 4566 4 nur nur NNP cord-015369-72cjogxz 4566 5 zu zu NNP cord-015369-72cjogxz 4566 6 einem einem NNP cord-015369-72cjogxz 4566 7 besseren besseren NNP cord-015369-72cjogxz 4566 8 ästhetischen ästhetischen NNP cord-015369-72cjogxz 4566 9 Behandlungsergebnis Behandlungsergebnis NNP cord-015369-72cjogxz 4566 10 , , , cord-015369-72cjogxz 4567 1 als als NNP cord-015369-72cjogxz 4567 2 es es NNP cord-015369-72cjogxz 4567 3 die die VBP cord-015369-72cjogxz 4567 4 isolierten isolierten NNP cord-015369-72cjogxz 4567 5 Straffungen Straffungen NNP cord-015369-72cjogxz 4567 6 der der NNP cord-015369-72cjogxz 4567 7 einzelnen einzelnen NNP cord-015369-72cjogxz 4567 8 Körperareale Körperareale NNP cord-015369-72cjogxz 4567 9 könnten könnten NN cord-015369-72cjogxz 4567 10 . . . cord-015369-72cjogxz 4568 1 Sondern Sondern NNP cord-015369-72cjogxz 4568 2 es es NNP cord-015369-72cjogxz 4568 3 trägt trägt NNP cord-015369-72cjogxz 4569 1 auch auch NNP cord-015369-72cjogxz 4569 2 zu zu NNP cord-015369-72cjogxz 4569 3 einer einer NNP cord-015369-72cjogxz 4569 4 Reduzierung Reduzierung NNP cord-015369-72cjogxz 4569 5 der der NNP cord-015369-72cjogxz 4569 6 sozioökonomischen sozioökonomischen NNP cord-015369-72cjogxz 4569 7 Kosten Kosten NNP cord-015369-72cjogxz 4570 1 durch durch NNP cord-015369-72cjogxz 4570 2 verkürzte verkürzte NNP cord-015369-72cjogxz 4570 3 Spitalsaufenthalte Spitalsaufenthalte NNP cord-015369-72cjogxz 4570 4 und und IN cord-015369-72cjogxz 4570 5 Krankenstände Krankenstände NNP cord-015369-72cjogxz 4571 1 i i PRP cord-015369-72cjogxz 4572 1 m m LS cord-015369-72cjogxz 4572 2 Vergleich Vergleich NNP cord-015369-72cjogxz 4572 3 zu zu NNP cord-015369-72cjogxz 4572 4 Einzelstraffungen Einzelstraffungen NNP cord-015369-72cjogxz 4572 5 bei bei NNP cord-015369-72cjogxz 4572 6 . . . cord-015369-72cjogxz 4573 1 Durch Durch NNP cord-015369-72cjogxz 4573 2 das das NNP cord-015369-72cjogxz 4573 3 standardisierte standardisierte NN cord-015369-72cjogxz 4573 4 Behandlungskonzept Behandlungskonzept NNP cord-015369-72cjogxz 4573 5 lässt lässt NNP cord-015369-72cjogxz 4573 6 sich sich NNP cord-015369-72cjogxz 4573 7 eine eine NNP cord-015369-72cjogxz 4573 8 hohe hohe NNP cord-015369-72cjogxz 4573 9 Patientensicherheit Patientensicherheit NNP cord-015369-72cjogxz 4573 10 und und NNP cord-015369-72cjogxz 4573 11 -zufriedenheit -zufriedenheit NNP cord-015369-72cjogxz 4573 12 erreichen erreichen NNP cord-015369-72cjogxz 4573 13 . . . cord-015369-72cjogxz 4574 1 Integriert Integriert NNP cord-015369-72cjogxz 4574 2 in in IN cord-015369-72cjogxz 4574 3 ein ein NNP cord-015369-72cjogxz 4574 4 interdisziplinäres interdisziplinäre NNS cord-015369-72cjogxz 4575 1 Team team NN cord-015369-72cjogxz 4575 2 aus aus NNP cord-015369-72cjogxz 4575 3 bariatrischen bariatrischen NNP cord-015369-72cjogxz 4575 4 Chirurgen Chirurgen NNP cord-015369-72cjogxz 4575 5 , , , cord-015369-72cjogxz 4575 6 Plastischen Plastischen NNP cord-015369-72cjogxz 4575 7 Chirurgen Chirurgen NNP cord-015369-72cjogxz 4575 8 , , , cord-015369-72cjogxz 4575 9 Internisten Internisten NNP cord-015369-72cjogxz 4575 10 , , , cord-015369-72cjogxz 4575 11 Psychologen Psychologen NNP cord-015369-72cjogxz 4575 12 , , , cord-015369-72cjogxz 4575 13 Ernährungsberatern Ernährungsberatern NNP cord-015369-72cjogxz 4575 14 und und IN cord-015369-72cjogxz 4575 15 Sportmedizinern Sportmedizinern NNP cord-015369-72cjogxz 4575 16 steht steht NNP cord-015369-72cjogxz 4575 17 eine eine NNP cord-015369-72cjogxz 4575 18 solche solche NNP cord-015369-72cjogxz 4575 19 Operation Operation NNP cord-015369-72cjogxz 4575 20 am be VBP cord-015369-72cjogxz 4575 21 Schluss Schluss NNP cord-015369-72cjogxz 4575 22 einer einer NNP cord-015369-72cjogxz 4576 1 langen langen NNP cord-015369-72cjogxz 4576 2 Behandlungsreihe Behandlungsreihe NNP cord-015369-72cjogxz 4577 1 und und IN cord-015369-72cjogxz 4577 2 erleichtert erleichtert NNP cord-015369-72cjogxz 4577 3 dem dem NNP cord-015369-72cjogxz 4577 4 Patient Patient NNP cord-015369-72cjogxz 4577 5 die die VBP cord-015369-72cjogxz 4577 6 Rückkehr Rückkehr NNP cord-015369-72cjogxz 4577 7 in in IN cord-015369-72cjogxz 4577 8 ein ein NNP cord-015369-72cjogxz 4577 9 normales normales NNPS cord-015369-72cjogxz 4577 10 Leben Leben NNP cord-015369-72cjogxz 4577 11 . . . cord-015369-72cjogxz 4578 1 Background background NN cord-015369-72cjogxz 4578 2 . . . cord-015369-72cjogxz 4579 1 Thyroid thyroid JJ cord-015369-72cjogxz 4579 2 autonomy autonomy NN cord-015369-72cjogxz 4579 3 shows show VBZ cord-015369-72cjogxz 4579 4 functional functional JJ cord-015369-72cjogxz 4579 5 and/or and/or CC cord-015369-72cjogxz 4579 6 autonomous autonomous JJ cord-015369-72cjogxz 4579 7 nodular nodular JJ cord-015369-72cjogxz 4579 8 growth growth NN cord-015369-72cjogxz 4579 9 . . . cord-015369-72cjogxz 4580 1 Should Should MD cord-015369-72cjogxz 4580 2 surgical surgical JJ cord-015369-72cjogxz 4580 3 therapy therapy NN cord-015369-72cjogxz 4580 4 remove remove VB cord-015369-72cjogxz 4580 5 affected affected JJ cord-015369-72cjogxz 4580 6 tissue tissue NN cord-015369-72cjogxz 4580 7 radically radically RB cord-015369-72cjogxz 4580 8 or or CC cord-015369-72cjogxz 4580 9 selectively selectively RB cord-015369-72cjogxz 4580 10 , , , cord-015369-72cjogxz 4580 11 with with IN cord-015369-72cjogxz 4580 12 risk risk NN cord-015369-72cjogxz 4580 13 of of IN cord-015369-72cjogxz 4580 14 hypothyroidism hypothyroidism NN cord-015369-72cjogxz 4580 15 or or CC cord-015369-72cjogxz 4580 16 risk risk NN cord-015369-72cjogxz 4580 17 of of IN cord-015369-72cjogxz 4580 18 functional functional JJ cord-015369-72cjogxz 4580 19 / / SYM cord-015369-72cjogxz 4580 20 nodular nodular JJ cord-015369-72cjogxz 4580 21 recurrence recurrence NN cord-015369-72cjogxz 4580 22 . . . cord-015369-72cjogxz 4581 1 Methods method NNS cord-015369-72cjogxz 4581 2 . . . cord-015369-72cjogxz 4582 1 A a DT cord-015369-72cjogxz 4582 2 prospective prospective JJ cord-015369-72cjogxz 4582 3 study study NN cord-015369-72cjogxz 4582 4 was be VBD cord-015369-72cjogxz 4582 5 conducted conduct VBN cord-015369-72cjogxz 4582 6 from from IN cord-015369-72cjogxz 4582 7 1982 1982 CD cord-015369-72cjogxz 4582 8 to to IN cord-015369-72cjogxz 4582 9 1985 1985 CD cord-015369-72cjogxz 4582 10 . . . cord-015369-72cjogxz 4583 1 Pts Pts NNP cord-015369-72cjogxz 4583 2 were be VBD cord-015369-72cjogxz 4583 3 stratified stratify VBN cord-015369-72cjogxz 4583 4 in in IN cord-015369-72cjogxz 4583 5 4 4 CD cord-015369-72cjogxz 4583 6 groups group NNS cord-015369-72cjogxz 4583 7 . . . cord-015369-72cjogxz 4584 1 First first JJ cord-015369-72cjogxz 4584 2 results result NNS cord-015369-72cjogxz 4584 3 in in IN cord-015369-72cjogxz 4584 4 outcome outcome NN cord-015369-72cjogxz 4584 5 were be VBD cord-015369-72cjogxz 4584 6 at at IN cord-015369-72cjogxz 4584 7 12 12 CD cord-015369-72cjogxz 4584 8 months month NNS cord-015369-72cjogxz 4584 9 , , , cord-015369-72cjogxz 4584 10 and and CC cord-015369-72cjogxz 4584 11 after after IN cord-015369-72cjogxz 4584 12 15 15 CD cord-015369-72cjogxz 4584 13 years year NNS cord-015369-72cjogxz 4584 14 . . . cord-015369-72cjogxz 4585 1 Late late JJ cord-015369-72cjogxz 4585 2 results result NNS cord-015369-72cjogxz 4585 3 are be VBP cord-015369-72cjogxz 4585 4 available available JJ cord-015369-72cjogxz 4585 5 25 25 CD cord-015369-72cjogxz 4585 6 years year NNS cord-015369-72cjogxz 4585 7 postoperatively postoperatively RB cord-015369-72cjogxz 4585 8 . . . cord-015369-72cjogxz 4586 1 Results result NNS cord-015369-72cjogxz 4586 2 . . . cord-015369-72cjogxz 4587 1 In in IN cord-015369-72cjogxz 4587 2 standard standard JJ cord-015369-72cjogxz 4587 3 bilateral bilateral JJ cord-015369-72cjogxz 4587 4 radical radical JJ cord-015369-72cjogxz 4587 5 resection resection NN cord-015369-72cjogxz 4587 6 , , , cord-015369-72cjogxz 4587 7 a a DT cord-015369-72cjogxz 4587 8 100 100 CD cord-015369-72cjogxz 4587 9 % % NN cord-015369-72cjogxz 4587 10 need need NN cord-015369-72cjogxz 4587 11 for for IN cord-015369-72cjogxz 4587 12 T4-medication t4-medication NN cord-015369-72cjogxz 4587 13 is be VBZ cord-015369-72cjogxz 4587 14 overt overt JJ cord-015369-72cjogxz 4587 15 , , , cord-015369-72cjogxz 4587 16 after after IN cord-015369-72cjogxz 4587 17 15 15 CD cord-015369-72cjogxz 4587 18 and and CC cord-015369-72cjogxz 4587 19 25 25 CD cord-015369-72cjogxz 4587 20 years year NNS cord-015369-72cjogxz 4587 21 in in IN cord-015369-72cjogxz 4587 22 less less JJR cord-015369-72cjogxz 4587 23 than than IN cord-015369-72cjogxz 4587 24 60 60 CD cord-015369-72cjogxz 4587 25 % % NN cord-015369-72cjogxz 4587 26 , , , cord-015369-72cjogxz 4587 27 with with IN cord-015369-72cjogxz 4587 28 a a DT cord-015369-72cjogxz 4587 29 2 2 CD cord-015369-72cjogxz 4587 30 % % NN cord-015369-72cjogxz 4587 31 risk risk NN cord-015369-72cjogxz 4587 32 of of IN cord-015369-72cjogxz 4587 33 recurrence recurrence NN cord-015369-72cjogxz 4587 34 . . . cord-015369-72cjogxz 4588 1 In in IN cord-015369-72cjogxz 4588 2 selective selective JJ cord-015369-72cjogxz 4588 3 nodule nodule NN cord-015369-72cjogxz 4588 4 removement removement NN cord-015369-72cjogxz 4589 1 a a DT cord-015369-72cjogxz 4589 2 lower low JJR cord-015369-72cjogxz 4589 3 rate rate NN cord-015369-72cjogxz 4589 4 of of IN cord-015369-72cjogxz 4589 5 hypothyroidism hypothyroidism NN cord-015369-72cjogxz 4589 6 with with IN cord-015369-72cjogxz 4589 7 a a DT cord-015369-72cjogxz 4589 8 10 10 CD cord-015369-72cjogxz 4589 9 % % NN cord-015369-72cjogxz 4589 10 risk risk NN cord-015369-72cjogxz 4589 11 of of IN cord-015369-72cjogxz 4589 12 recurrence recurrence NN cord-015369-72cjogxz 4589 13 is be VBZ cord-015369-72cjogxz 4589 14 noted note VBN cord-015369-72cjogxz 4589 15 . . . cord-015369-72cjogxz 4590 1 Conclusions conclusion NNS cord-015369-72cjogxz 4590 2 . . . cord-015369-72cjogxz 4591 1 AFTT AFTT NNP cord-015369-72cjogxz 4591 2 should should MD cord-015369-72cjogxz 4591 3 be be VB cord-015369-72cjogxz 4591 4 treated treat VBN cord-015369-72cjogxz 4591 5 by by IN cord-015369-72cjogxz 4591 6 adequate adequate JJ cord-015369-72cjogxz 4591 7 bilateral bilateral JJ cord-015369-72cjogxz 4591 8 resection resection NN cord-015369-72cjogxz 4591 9 , , , cord-015369-72cjogxz 4591 10 selective selective JJ cord-015369-72cjogxz 4591 11 nodular nodular JJ cord-015369-72cjogxz 4591 12 removement removement NN cord-015369-72cjogxz 4591 13 has have VBZ cord-015369-72cjogxz 4591 14 a a DT cord-015369-72cjogxz 4591 15 high high JJ cord-015369-72cjogxz 4591 16 risk risk NN cord-015369-72cjogxz 4591 17 of of IN cord-015369-72cjogxz 4591 18 functional functional JJ cord-015369-72cjogxz 4591 19 and and CC cord-015369-72cjogxz 4591 20 nodular nodular JJ cord-015369-72cjogxz 4591 21 persistance persistance NN cord-015369-72cjogxz 4591 22 or or CC cord-015369-72cjogxz 4591 23 recurrence recurrence NN cord-015369-72cjogxz 4591 24 . . . cord-015369-72cjogxz 4592 1 Evaluation evaluation NN cord-015369-72cjogxz 4592 2 of of IN cord-015369-72cjogxz 4592 3 parathyroid parathyroid JJ cord-015369-72cjogxz 4592 4 hormone hormone NN cord-015369-72cjogxz 4592 5 screening screening NN cord-015369-72cjogxz 4592 6 before before IN cord-015369-72cjogxz 4592 7 thyreoidectomy thyreoidectomy NN cord-015369-72cjogxz 4592 8 Methodik Methodik NNP cord-015369-72cjogxz 4592 9 . . . cord-015369-72cjogxz 4593 1 Eine Eine NNP cord-015369-72cjogxz 4593 2 perioperative perioperative JJ cord-015369-72cjogxz 4593 3 PTH PTH NNP cord-015369-72cjogxz 4593 4 - - HYPH cord-015369-72cjogxz 4593 5 Bestimmung Bestimmung NNP cord-015369-72cjogxz 4593 6 wurde wurde NN cord-015369-72cjogxz 4593 7 bei bei NNP cord-015369-72cjogxz 4593 8 316 316 CD cord-015369-72cjogxz 4594 1 konsekutiven konsekutiven NNP cord-015369-72cjogxz 4594 2 normocalcämischen normocalcämischen NNP cord-015369-72cjogxz 4594 3 PatientInnen PatientInnen NNP cord-015369-72cjogxz 4594 4 durchgeführt durchgeführt NN cord-015369-72cjogxz 4594 5 . . . cord-015369-72cjogxz 4595 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4595 2 . . . cord-015369-72cjogxz 4596 1 31 31 CD cord-015369-72cjogxz 4596 2 von von NNP cord-015369-72cjogxz 4596 3 316 316 CD cord-015369-72cjogxz 4596 4 Patientinnen Patientinnen NNP cord-015369-72cjogxz 4596 5 ( ( -LRB- cord-015369-72cjogxz 4596 6 9,8 9,8 CD cord-015369-72cjogxz 4596 7 % % NN cord-015369-72cjogxz 4596 8 ) ) -RRB- cord-015369-72cjogxz 4596 9 wiesen wiesen NNP cord-015369-72cjogxz 4596 10 erhöhte erhöhte NNP cord-015369-72cjogxz 4596 11 PTH PTH NNP cord-015369-72cjogxz 4596 12 - - HYPH cord-015369-72cjogxz 4596 13 Spiegel Spiegel NNP cord-015369-72cjogxz 4596 14 auf auf NNP cord-015369-72cjogxz 4596 15 ( ( -LRB- cord-015369-72cjogxz 4596 16 Gruppe Gruppe NNP cord-015369-72cjogxz 4596 17 A A NNP cord-015369-72cjogxz 4596 18 ) ) -RRB- cord-015369-72cjogxz 4596 19 , , , cord-015369-72cjogxz 4596 20 durchschnittlich durchschnittlich NN cord-015369-72cjogxz 4596 21 84,25 84,25 CD cord-015369-72cjogxz 4596 22 pg pg NNP cord-015369-72cjogxz 4596 23 / / SYM cord-015369-72cjogxz 4596 24 ml ml NN cord-015369-72cjogxz 4597 1 ( ( -LRB- cord-015369-72cjogxz 4597 2 Normalbereich Normalbereich NNP cord-015369-72cjogxz 4597 3 11 11 CD cord-015369-72cjogxz 4597 4 - - SYM cord-015369-72cjogxz 4597 5 67 67 CD cord-015369-72cjogxz 4597 6 pg pg NN cord-015369-72cjogxz 4597 7 / / SYM cord-015369-72cjogxz 4597 8 ml ml NN cord-015369-72cjogxz 4597 9 , , , cord-015369-72cjogxz 4598 1 Range range NN cord-015369-72cjogxz 4598 2 67,5 67,5 CD cord-015369-72cjogxz 4598 3 - - SYM cord-015369-72cjogxz 4598 4 134 134 CD cord-015369-72cjogxz 4598 5 ) ) -RRB- cord-015369-72cjogxz 4598 6 , , , cord-015369-72cjogxz 4598 7 bei bei NNP cord-015369-72cjogxz 4598 8 285 285 CD cord-015369-72cjogxz 4599 1 Patientinnen Patientinnen NNP cord-015369-72cjogxz 4599 2 mit mit VBD cord-015369-72cjogxz 4599 3 normalem normalem NNP cord-015369-72cjogxz 4599 4 PTH PTH NNP cord-015369-72cjogxz 4599 5 ( ( -LRB- cord-015369-72cjogxz 4599 6 Gruppe Gruppe NNP cord-015369-72cjogxz 4599 7 B B NNP cord-015369-72cjogxz 4599 8 ) ) -RRB- cord-015369-72cjogxz 4599 9 lag lag VB cord-015369-72cjogxz 4599 10 der der NN cord-015369-72cjogxz 4599 11 Wert Wert NNP cord-015369-72cjogxz 4599 12 bei bei NNP cord-015369-72cjogxz 4599 13 36,90 36,90 CD cord-015369-72cjogxz 4600 1 ( ( -LRB- cord-015369-72cjogxz 4600 2 Range Range NNP cord-015369-72cjogxz 4600 3 12 12 CD cord-015369-72cjogxz 4600 4 , , , cord-015369-72cjogxz 4600 5 7 7 CD cord-015369-72cjogxz 4600 6 ) ) -RRB- cord-015369-72cjogxz 4600 7 . . . cord-015369-72cjogxz 4601 1 Die die VB cord-015369-72cjogxz 4601 2 Ca Ca NNP cord-015369-72cjogxz 4601 3 - - HYPH cord-015369-72cjogxz 4601 4 Werte Werte NNP cord-015369-72cjogxz 4601 5 waren waren NNP cord-015369-72cjogxz 4601 6 in in IN cord-015369-72cjogxz 4601 7 beiden beiden JJ cord-015369-72cjogxz 4601 8 Gruppen Gruppen NNP cord-015369-72cjogxz 4601 9 gleich gleich NNP cord-015369-72cjogxz 4601 10 ( ( -LRB- cord-015369-72cjogxz 4601 11 Gruppe Gruppe NNP cord-015369-72cjogxz 4601 12 A A NNP cord-015369-72cjogxz 4601 13 2,28 2,28 CD cord-015369-72cjogxz 4601 14 mmol mmol NNP cord-015369-72cjogxz 4601 15 / / SYM cord-015369-72cjogxz 4601 16 l l NN cord-015369-72cjogxz 4601 17 , , , cord-015369-72cjogxz 4601 18 Range Range NNP cord-015369-72cjogxz 4601 19 2,06 2,06 CD cord-015369-72cjogxz 4601 20 - - HYPH cord-015369-72cjogxz 4601 21 2,54 2,54 CD cord-015369-72cjogxz 4601 22 , , , cord-015369-72cjogxz 4601 23 Gruppe Gruppe NNP cord-015369-72cjogxz 4601 24 B B NNP cord-015369-72cjogxz 4601 25 2,26 2,26 CD cord-015369-72cjogxz 4601 26 mmol mmol NNP cord-015369-72cjogxz 4601 27 / / SYM cord-015369-72cjogxz 4601 28 l l NN cord-015369-72cjogxz 4601 29 , , , cord-015369-72cjogxz 4601 30 Range Range NNP cord-015369-72cjogxz 4601 31 1,98 1,98 CD cord-015369-72cjogxz 4601 32 - - HYPH cord-015369-72cjogxz 4601 33 2,47 2,47 CD cord-015369-72cjogxz 4601 34 ) ) -RRB- cord-015369-72cjogxz 4601 35 . . . cord-015369-72cjogxz 4602 1 Bei Bei NNP cord-015369-72cjogxz 4602 2 den den NNP cord-015369-72cjogxz 4602 3 31 31 CD cord-015369-72cjogxz 4602 4 Patien Patien NNP cord-015369-72cjogxz 4602 5 - - HYPH cord-015369-72cjogxz 4602 6 tinnen tinnen NNP cord-015369-72cjogxz 4602 7 der der NNP cord-015369-72cjogxz 4602 8 Gruppe Gruppe NNP cord-015369-72cjogxz 4602 9 A A NNP cord-015369-72cjogxz 4602 10 wurden wurden VBD cord-015369-72cjogxz 4602 11 53 53 CD cord-015369-72cjogxz 4602 12 Schilddrü Schilddrü NNP cord-015369-72cjogxz 4602 13 senlappen senlappen NNP cord-015369-72cjogxz 4602 14 operiert operiert NNP cord-015369-72cjogxz 4602 15 . . . cord-015369-72cjogxz 4603 1 69 69 CD cord-015369-72cjogxz 4604 1 ( ( -LRB- cord-015369-72cjogxz 4604 2 von von NNP cord-015369-72cjogxz 4604 3 106 106 CD cord-015369-72cjogxz 4604 4 ) ) -RRB- cord-015369-72cjogxz 4605 1 Nebenschilddrü Nebenschilddrü NNP cord-015369-72cjogxz 4605 2 sen sen NNP cord-015369-72cjogxz 4605 3 konnten konnten NNP cord-015369-72cjogxz 4605 4 exploriert exploriert NNP cord-015369-72cjogxz 4605 5 werden werden NNP cord-015369-72cjogxz 4605 6 , , , cord-015369-72cjogxz 4605 7 68 68 CD cord-015369-72cjogxz 4605 8 ohne ohne NNP cord-015369-72cjogxz 4605 9 pathologischen pathologischen NNP cord-015369-72cjogxz 4605 10 Befund Befund NNP cord-015369-72cjogxz 4605 11 , , , cord-015369-72cjogxz 4605 12 einmal einmal NNP cord-015369-72cjogxz 4605 13 wurde wurde NNP cord-015369-72cjogxz 4605 14 ein ein NNP cord-015369-72cjogxz 4605 15 Nebenschilddrü Nebenschilddrü NNP cord-015369-72cjogxz 4605 16 senadenom senadenom XX cord-015369-72cjogxz 4605 17 als als NNP cord-015369-72cjogxz 4605 18 Ausdruck Ausdruck NNP cord-015369-72cjogxz 4605 19 eines eines NNP cord-015369-72cjogxz 4605 20 primären primären NNP cord-015369-72cjogxz 4605 21 HPT HPT NNP cord-015369-72cjogxz 4605 22 gefunden gefunden NNP cord-015369-72cjogxz 4605 23 . . . cord-015369-72cjogxz 4606 1 Postoperativ Postoperativ NNP cord-015369-72cjogxz 4606 2 wies wy NNS cord-015369-72cjogxz 4606 3 die die VBP cord-015369-72cjogxz 4606 4 Gruppe Gruppe NNP cord-015369-72cjogxz 4606 5 A a DT cord-015369-72cjogxz 4606 6 einen einen JJ cord-015369-72cjogxz 4606 7 durchschnittlichen durchschnittlichen FW cord-015369-72cjogxz 4606 8 PTH PTH NNP cord-015369-72cjogxz 4606 9 - - HYPH cord-015369-72cjogxz 4606 10 Wert Wert NNP cord-015369-72cjogxz 4606 11 von von NNP cord-015369-72cjogxz 4606 12 38,41 38,41 CD cord-015369-72cjogxz 4606 13 pg pg NNP cord-015369-72cjogxz 4606 14 / / SYM cord-015369-72cjogxz 4606 15 ml ml XX cord-015369-72cjogxz 4606 16 bei bei NNP cord-015369-72cjogxz 4606 17 einem einem NNP cord-015369-72cjogxz 4606 18 durchschnittlichem durchschnittlichem NNP cord-015369-72cjogxz 4607 1 Ca Ca NNP cord-015369-72cjogxz 4607 2 - - HYPH cord-015369-72cjogxz 4607 3 Wert Wert NNP cord-015369-72cjogxz 4607 4 von von NNP cord-015369-72cjogxz 4607 5 2,07 2,07 CD cord-015369-72cjogxz 4608 1 ( ( -LRB- cord-015369-72cjogxz 4608 2 Range range NN cord-015369-72cjogxz 4608 3 1,77 1,77 CD cord-015369-72cjogxz 4608 4 - - HYPH cord-015369-72cjogxz 4608 5 2,30 2,30 CD cord-015369-72cjogxz 4608 6 ) ) -RRB- cord-015369-72cjogxz 4608 7 auf auf NNP cord-015369-72cjogxz 4608 8 , , , cord-015369-72cjogxz 4608 9 Gruppe Gruppe NNP cord-015369-72cjogxz 4608 10 B B NNP cord-015369-72cjogxz 4608 11 einen einen NNP cord-015369-72cjogxz 4608 12 durchschnittlichen durchschnittlichen NNP cord-015369-72cjogxz 4608 13 PTH PTH NNP cord-015369-72cjogxz 4608 14 - - HYPH cord-015369-72cjogxz 4608 15 Wert Wert NNP cord-015369-72cjogxz 4608 16 von von NNP cord-015369-72cjogxz 4608 17 23,06 23,06 CD cord-015369-72cjogxz 4608 18 bei bei NNP cord-015369-72cjogxz 4608 19 einem einem NNP cord-015369-72cjogxz 4608 20 durchschnittlichem durchschnittlichem NNP cord-015369-72cjogxz 4609 1 Ca Ca NNP cord-015369-72cjogxz 4609 2 von von NNP cord-015369-72cjogxz 4609 3 2,09 2,09 CD cord-015369-72cjogxz 4610 1 ( ( -LRB- cord-015369-72cjogxz 4610 2 Range range NN cord-015369-72cjogxz 4610 3 1,73 1,73 CD cord-015369-72cjogxz 4610 4 bis bis NNP cord-015369-72cjogxz 4610 5 2,37 2,37 CD cord-015369-72cjogxz 4610 6 ) ) -RRB- cord-015369-72cjogxz 4610 7 . . . cord-015369-72cjogxz 4611 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4611 2 . . . cord-015369-72cjogxz 4612 1 Präoperativ Präoperativ NNP cord-015369-72cjogxz 4612 2 erhöhte erhöhte NNP cord-015369-72cjogxz 4613 1 PTH PTH NNP cord-015369-72cjogxz 4613 2 - - HYPH cord-015369-72cjogxz 4613 3 Spiegel Spiegel NNP cord-015369-72cjogxz 4613 4 bei bei NNP cord-015369-72cjogxz 4613 5 Normocalcämie Normocalcämie NNP cord-015369-72cjogxz 4613 6 sind sind NNP cord-015369-72cjogxz 4613 7 bei bei NNP cord-015369-72cjogxz 4613 8 jedem jedem NNP cord-015369-72cjogxz 4614 1 zehnten zehnten NNP cord-015369-72cjogxz 4615 1 Patienten Patienten NNP cord-015369-72cjogxz 4615 2 zu zu IN cord-015369-72cjogxz 4615 3 finden finden NNP cord-015369-72cjogxz 4615 4 ; ; : cord-015369-72cjogxz 4615 5 dabei dabei NNP cord-015369-72cjogxz 4615 6 liegt liegt NNP cord-015369-72cjogxz 4615 7 nur nur NNP cord-015369-72cjogxz 4615 8 selten selten NNP cord-015369-72cjogxz 4615 9 ein ein NNP cord-015369-72cjogxz 4615 10 normocalcämischer normocalcämischer NN cord-015369-72cjogxz 4615 11 primärer primärer NN cord-015369-72cjogxz 4615 12 Hyperparathyreoidismus Hyperparathyreoidismus NNP cord-015369-72cjogxz 4615 13 vor vor NNP cord-015369-72cjogxz 4615 14 , , , cord-015369-72cjogxz 4615 15 sondern sondern NNP cord-015369-72cjogxz 4615 16 ü ü NNP cord-015369-72cjogxz 4615 17 berwiegend berwiegend NNP cord-015369-72cjogxz 4615 18 eine eine NNP cord-015369-72cjogxz 4615 19 reaktive reaktive NNP cord-015369-72cjogxz 4616 1 Hyperparathyrinämie Hyperparathyrinämie NNP cord-015369-72cjogxz 4616 2 . . . cord-015369-72cjogxz 4617 1 Ein Ein NNP cord-015369-72cjogxz 4617 2 generelles generelle VBZ cord-015369-72cjogxz 4617 3 PTH PTH NNP cord-015369-72cjogxz 4617 4 Screening Screening NNP cord-015369-72cjogxz 4617 5 kann kann NNP cord-015369-72cjogxz 4617 6 daher daher NNP cord-015369-72cjogxz 4617 7 nicht nicht NNP cord-015369-72cjogxz 4617 8 empfohlen empfohlen NNP cord-015369-72cjogxz 4617 9 werden werden NNP cord-015369-72cjogxz 4617 10 , , , cord-015369-72cjogxz 4617 11 es es NNP cord-015369-72cjogxz 4617 12 ist ist FW cord-015369-72cjogxz 4617 13 aber aber NNP cord-015369-72cjogxz 4617 14 sinnvoll sinnvoll NNP cord-015369-72cjogxz 4617 15 , , , cord-015369-72cjogxz 4617 16 wenn wenn NNP cord-015369-72cjogxz 4617 17 das das NNP cord-015369-72cjogxz 4617 18 präoperativ präoperativ NNP cord-015369-72cjogxz 4618 1 obligate obligate VB cord-015369-72cjogxz 4618 2 Calcium Calcium NNP cord-015369-72cjogxz 4619 1 i -PRON- PRP cord-015369-72cjogxz 4619 2 m be VBP cord-015369-72cjogxz 4619 3 oberen oberen NNP cord-015369-72cjogxz 4619 4 Normbereich Normbereich NNP cord-015369-72cjogxz 4619 5 liegt liegt NNP cord-015369-72cjogxz 4619 6 . . . cord-015369-72cjogxz 4620 1 Eine Eine NNP cord-015369-72cjogxz 4620 2 Exploration Exploration NNP cord-015369-72cjogxz 4620 3 der der NNP cord-015369-72cjogxz 4620 4 Nebenschilddrü Nebenschilddrü NNP cord-015369-72cjogxz 4621 1 sen sen NNP cord-015369-72cjogxz 4621 2 ist ist NNP cord-015369-72cjogxz 4622 1 i i PRP cord-015369-72cjogxz 4623 1 m m NNP cord-015369-72cjogxz 4623 2 Rahmen Rahmen NNP cord-015369-72cjogxz 4623 3 der der NNP cord-015369-72cjogxz 4623 4 geplanten geplanten NNP cord-015369-72cjogxz 4623 5 Schilddrü Schilddrü NNP cord-015369-72cjogxz 4623 6 senoperation senoperation NN cord-015369-72cjogxz 4623 7 angezeigt angezeigt NNP cord-015369-72cjogxz 4623 8 , , , cord-015369-72cjogxz 4623 9 eine eine NNP cord-015369-72cjogxz 4623 10 Ausweitung Ausweitung NNP cord-015369-72cjogxz 4623 11 des des FW cord-015369-72cjogxz 4623 12 Eingriffs Eingriffs NNP cord-015369-72cjogxz 4624 1 zur zur NNP cord-015369-72cjogxz 4624 2 4-Drü 4-Drü NNP cord-015369-72cjogxz 4624 3 senexploration senexploration NN cord-015369-72cjogxz 4624 4 , , , cord-015369-72cjogxz 4624 5 , , , cord-015369-72cjogxz 4624 6 , , , cord-015369-72cjogxz 4624 7 en en FW cord-015369-72cjogxz 4624 8 principe principe NNP cord-015369-72cjogxz 4624 9 ' ' '' cord-015369-72cjogxz 4624 10 ' ' `` cord-015369-72cjogxz 4624 11 allerdings allerdings NNP cord-015369-72cjogxz 4624 12 nicht nicht NNP cord-015369-72cjogxz 4624 13 . . . cord-015369-72cjogxz 4625 1 Reoperation reoperation NN cord-015369-72cjogxz 4625 2 in in IN cord-015369-72cjogxz 4625 3 recurrent recurrent JJ cord-015369-72cjogxz 4625 4 goiter goiter NN cord-015369-72cjogxz 4625 5 is be VBZ cord-015369-72cjogxz 4625 6 associated associate VBN cord-015369-72cjogxz 4625 7 with with IN cord-015369-72cjogxz 4625 8 an an DT cord-015369-72cjogxz 4625 9 elevated elevated JJ cord-015369-72cjogxz 4625 10 morbidity morbidity NN cord-015369-72cjogxz 4625 11 predominantly predominantly RB cord-015369-72cjogxz 4625 12 related relate VBN cord-015369-72cjogxz 4625 13 to to IN cord-015369-72cjogxz 4625 14 recurrent recurrent JJ cord-015369-72cjogxz 4625 15 laryngeal laryngeal JJ cord-015369-72cjogxz 4625 16 nerve nerve NN cord-015369-72cjogxz 4625 17 palsy palsy NN cord-015369-72cjogxz 4625 18 between between IN cord-015369-72cjogxz 4625 19 2 2 CD cord-015369-72cjogxz 4625 20 and and CC cord-015369-72cjogxz 4625 21 20 20 CD cord-015369-72cjogxz 4625 22 % % NN cord-015369-72cjogxz 4625 23 . . . cord-015369-72cjogxz 4626 1 A a DT cord-015369-72cjogxz 4626 2 benefit benefit NN cord-015369-72cjogxz 4626 3 of of IN cord-015369-72cjogxz 4626 4 intraoperative intraoperative JJ cord-015369-72cjogxz 4626 5 neuromonitoring neuromonitoring NN cord-015369-72cjogxz 4626 6 ( ( -LRB- cord-015369-72cjogxz 4626 7 IONM IONM NNP cord-015369-72cjogxz 4626 8 ) ) -RRB- cord-015369-72cjogxz 4626 9 in in IN cord-015369-72cjogxz 4626 10 reoperative reoperative JJ cord-015369-72cjogxz 4626 11 surgery surgery NN cord-015369-72cjogxz 4626 12 focusing focus VBG cord-015369-72cjogxz 4626 13 on on IN cord-015369-72cjogxz 4626 14 the the DT cord-015369-72cjogxz 4626 15 recurrent recurrent JJ cord-015369-72cjogxz 4626 16 laryngeal laryngeal JJ cord-015369-72cjogxz 4626 17 nerve nerve NN cord-015369-72cjogxz 4626 18 palsy palsy NN cord-015369-72cjogxz 4626 19 rate rate NN cord-015369-72cjogxz 4626 20 has have VBZ cord-015369-72cjogxz 4626 21 not not RB cord-015369-72cjogxz 4626 22 been be VBN cord-015369-72cjogxz 4626 23 demonstrated demonstrate VBN cord-015369-72cjogxz 4626 24 clearly clearly RB cord-015369-72cjogxz 4626 25 . . . cord-015369-72cjogxz 4627 1 In in IN cord-015369-72cjogxz 4627 2 a a DT cord-015369-72cjogxz 4627 3 retrospective retrospective JJ cord-015369-72cjogxz 4627 4 analysis analysis NN cord-015369-72cjogxz 4627 5 ( ( -LRB- cord-015369-72cjogxz 4627 6 1995 1995 CD cord-015369-72cjogxz 4627 7 ) ) -RRB- cord-015369-72cjogxz 4627 8 ( ( -LRB- cord-015369-72cjogxz 4627 9 1996 1996 CD cord-015369-72cjogxz 4627 10 ) ) -RRB- cord-015369-72cjogxz 4627 11 ( ( -LRB- cord-015369-72cjogxz 4627 12 1997 1997 CD cord-015369-72cjogxz 4627 13 ) ) -RRB- cord-015369-72cjogxz 4627 14 ( ( -LRB- cord-015369-72cjogxz 4627 15 1998 1998 CD cord-015369-72cjogxz 4627 16 ) ) -RRB- cord-015369-72cjogxz 4627 17 ( ( -LRB- cord-015369-72cjogxz 4627 18 1999 1999 CD cord-015369-72cjogxz 4627 19 ) ) -RRB- cord-015369-72cjogxz 4627 20 ( ( -LRB- cord-015369-72cjogxz 4627 21 2000 2000 CD cord-015369-72cjogxz 4627 22 ) ) -RRB- cord-015369-72cjogxz 4627 23 ( ( -LRB- cord-015369-72cjogxz 4627 24 2001 2001 CD cord-015369-72cjogxz 4627 25 ) ) -RRB- cord-015369-72cjogxz 4627 26 ( ( -LRB- cord-015369-72cjogxz 4627 27 2002 2002 CD cord-015369-72cjogxz 4627 28 ) ) -RRB- cord-015369-72cjogxz 4627 29 ( ( -LRB- cord-015369-72cjogxz 4627 30 2003 2003 CD cord-015369-72cjogxz 4627 31 ) ) -RRB- cord-015369-72cjogxz 4627 32 ( ( -LRB- cord-015369-72cjogxz 4627 33 2004 2004 CD cord-015369-72cjogxz 4627 34 ) ) -RRB- cord-015369-72cjogxz 4627 35 ( ( -LRB- cord-015369-72cjogxz 4627 36 2005 2005 CD cord-015369-72cjogxz 4627 37 ) ) -RRB- cord-015369-72cjogxz 4627 38 of of IN cord-015369-72cjogxz 4627 39 430 430 CD cord-015369-72cjogxz 4627 40 nerves nerve NNS cord-015369-72cjogxz 4627 41 at at IN cord-015369-72cjogxz 4627 42 risk risk NN cord-015369-72cjogxz 4627 43 ( ( -LRB- cord-015369-72cjogxz 4627 44 NAR NAR NNP cord-015369-72cjogxz 4627 45 ) ) -RRB- cord-015369-72cjogxz 4627 46 in in IN cord-015369-72cjogxz 4627 47 reoperative reoperative JJ cord-015369-72cjogxz 4627 48 thyroid thyroid NN cord-015369-72cjogxz 4627 49 surgery surgery NN cord-015369-72cjogxz 4627 50 at at IN cord-015369-72cjogxz 4627 51 our -PRON- PRP$ cord-015369-72cjogxz 4627 52 institution institution NN cord-015369-72cjogxz 4627 53 by by IN cord-015369-72cjogxz 4627 54 using use VBG cord-015369-72cjogxz 4627 55 neuromonitoring neuromonitore VBG cord-015369-72cjogxz 4627 56 ( ( -LRB- cord-015369-72cjogxz 4627 57 223 223 CD cord-015369-72cjogxz 4627 58 NAR NAR NNP cord-015369-72cjogxz 4627 59 ) ) -RRB- cord-015369-72cjogxz 4627 60 or or CC cord-015369-72cjogxz 4627 61 visual visual JJ cord-015369-72cjogxz 4627 62 nerve nerve NN cord-015369-72cjogxz 4627 63 identification identification NN cord-015369-72cjogxz 4627 64 ( ( -LRB- cord-015369-72cjogxz 4627 65 207 207 CD cord-015369-72cjogxz 4627 66 NAR NAR NNP cord-015369-72cjogxz 4627 67 ) ) -RRB- cord-015369-72cjogxz 4628 1 transient transient JJ cord-015369-72cjogxz 4628 2 recurrent recurrent JJ cord-015369-72cjogxz 4628 3 laryngeal laryngeal JJ cord-015369-72cjogxz 4628 4 nerve nerve NN cord-015369-72cjogxz 4628 5 palsy palsy NN cord-015369-72cjogxz 4628 6 rate rate NN cord-015369-72cjogxz 4628 7 was be VBD cord-015369-72cjogxz 4628 8 comparable comparable JJ cord-015369-72cjogxz 4628 9 between between IN cord-015369-72cjogxz 4628 10 both both DT cord-015369-72cjogxz 4628 11 groups group NNS cord-015369-72cjogxz 4628 12 ( ( -LRB- cord-015369-72cjogxz 4628 13 11.6 11.6 CD cord-015369-72cjogxz 4628 14 and and CC cord-015369-72cjogxz 4628 15 12.1 12.1 CD cord-015369-72cjogxz 4628 16 % % NN cord-015369-72cjogxz 4628 17 ) ) -RRB- cord-015369-72cjogxz 4628 18 . . . cord-015369-72cjogxz 4629 1 However however RB cord-015369-72cjogxz 4629 2 a a DT cord-015369-72cjogxz 4629 3 clear clear JJ cord-015369-72cjogxz 4629 4 reduction reduction NN cord-015369-72cjogxz 4629 5 in in IN cord-015369-72cjogxz 4629 6 permanent permanent JJ cord-015369-72cjogxz 4629 7 recurrent recurrent JJ cord-015369-72cjogxz 4629 8 laryngeal laryngeal NN cord-015369-72cjogxz 4629 9 nerve nerve NN cord-015369-72cjogxz 4629 10 palsy palsy JJ cord-015369-72cjogxz 4629 11 by by IN cord-015369-72cjogxz 4629 12 using use VBG cord-015369-72cjogxz 4629 13 neuromonitoring neuromonitore VBG cord-015369-72cjogxz 4629 14 from from IN cord-015369-72cjogxz 4629 15 11.2 11.2 CD cord-015369-72cjogxz 4629 16 to to IN cord-015369-72cjogxz 4629 17 4.4 4.4 CD cord-015369-72cjogxz 4629 18 % % NN cord-015369-72cjogxz 4629 19 was be VBD cord-015369-72cjogxz 4629 20 evident evident JJ cord-015369-72cjogxz 4629 21 . . . cord-015369-72cjogxz 4630 1 After after IN cord-015369-72cjogxz 4630 2 standardizing standardize VBG cord-015369-72cjogxz 4630 3 IONM ionm PRP cord-015369-72cjogxz 4630 4 in in IN cord-015369-72cjogxz 4630 5 our -PRON- PRP$ cord-015369-72cjogxz 4630 6 clinic clinic NN cord-015369-72cjogxz 4630 7 , , , cord-015369-72cjogxz 4630 8 we -PRON- PRP cord-015369-72cjogxz 4630 9 started start VBD cord-015369-72cjogxz 4630 10 a a DT cord-015369-72cjogxz 4630 11 prospective prospective JJ cord-015369-72cjogxz 4630 12 study study NN cord-015369-72cjogxz 4630 13 to to TO cord-015369-72cjogxz 4630 14 confirm confirm VB cord-015369-72cjogxz 4630 15 this this DT cord-015369-72cjogxz 4630 16 finding finding NN cord-015369-72cjogxz 4630 17 and and CC cord-015369-72cjogxz 4630 18 to to TO cord-015369-72cjogxz 4630 19 define define VB cord-015369-72cjogxz 4630 20 the the DT cord-015369-72cjogxz 4630 21 influence influence NN cord-015369-72cjogxz 4630 22 of of IN cord-015369-72cjogxz 4630 23 IONM IONM NNP cord-015369-72cjogxz 4630 24 on on IN cord-015369-72cjogxz 4630 25 transient transient JJ cord-015369-72cjogxz 4630 26 recurrent recurrent JJ cord-015369-72cjogxz 4630 27 laryngeal laryngeal JJ cord-015369-72cjogxz 4630 28 nerve nerve NN cord-015369-72cjogxz 4630 29 palsy palsy NN cord-015369-72cjogxz 4630 30 rate rate NN cord-015369-72cjogxz 4630 31 . . . cord-015369-72cjogxz 4631 1 All all DT cord-015369-72cjogxz 4631 2 reoperations reoperation NNS cord-015369-72cjogxz 4631 3 in in IN cord-015369-72cjogxz 4631 4 thyroid thyroid NN cord-015369-72cjogxz 4631 5 diseases disease NNS cord-015369-72cjogxz 4631 6 by by IN cord-015369-72cjogxz 4631 7 using use VBG cord-015369-72cjogxz 4631 8 neuromonitoring neuromonitore VBG cord-015369-72cjogxz 4631 9 ( ( -LRB- cord-015369-72cjogxz 4631 10 63 63 CD cord-015369-72cjogxz 4631 11 NAR NAR NNP cord-015369-72cjogxz 4631 12 ) ) -RRB- cord-015369-72cjogxz 4631 13 from from IN cord-015369-72cjogxz 4631 14 January January NNP cord-015369-72cjogxz 4631 15 2006 2006 CD cord-015369-72cjogxz 4631 16 were be VBD cord-015369-72cjogxz 4631 17 included include VBN cord-015369-72cjogxz 4631 18 in in IN cord-015369-72cjogxz 4631 19 this this DT cord-015369-72cjogxz 4631 20 analysis analysis NN cord-015369-72cjogxz 4631 21 with with IN cord-015369-72cjogxz 4631 22 respect respect NN cord-015369-72cjogxz 4631 23 to to IN cord-015369-72cjogxz 4631 24 the the DT cord-015369-72cjogxz 4631 25 transient transient JJ cord-015369-72cjogxz 4631 26 and and CC cord-015369-72cjogxz 4631 27 permanent permanent JJ cord-015369-72cjogxz 4631 28 recurrent recurrent JJ cord-015369-72cjogxz 4631 29 laryngeal laryngeal JJ cord-015369-72cjogxz 4631 30 nerve nerve NN cord-015369-72cjogxz 4631 31 paralysis paralysis NN cord-015369-72cjogxz 4631 32 rate rate NN cord-015369-72cjogxz 4631 33 . . . cord-015369-72cjogxz 4632 1 The the DT cord-015369-72cjogxz 4632 2 prospective prospective JJ cord-015369-72cjogxz 4632 3 evaluation evaluation NN cord-015369-72cjogxz 4632 4 of of IN cord-015369-72cjogxz 4632 5 63 63 CD cord-015369-72cjogxz 4632 6 NAR NAR NNP cord-015369-72cjogxz 4632 7 in in IN cord-015369-72cjogxz 4632 8 reoperative reoperative JJ cord-015369-72cjogxz 4632 9 thyroid thyroid NN cord-015369-72cjogxz 4632 10 surgery surgery NN cord-015369-72cjogxz 4632 11 shows show VBZ cord-015369-72cjogxz 4632 12 a a DT cord-015369-72cjogxz 4632 13 decreased decrease VBN cord-015369-72cjogxz 4632 14 transient transient JJ cord-015369-72cjogxz 4632 15 ( ( -LRB- cord-015369-72cjogxz 4632 16 6.7 6.7 CD cord-015369-72cjogxz 4632 17 % % NN cord-015369-72cjogxz 4632 18 ) ) -RRB- cord-015369-72cjogxz 4632 19 and and CC cord-015369-72cjogxz 4632 20 permanent permanent JJ cord-015369-72cjogxz 4632 21 ( ( -LRB- cord-015369-72cjogxz 4632 22 1.7 1.7 CD cord-015369-72cjogxz 4632 23 % % NN cord-015369-72cjogxz 4632 24 ) ) -RRB- cord-015369-72cjogxz 4633 1 recurrent recurrent JJ cord-015369-72cjogxz 4633 2 laryngeal laryngeal JJ cord-015369-72cjogxz 4633 3 nerve nerve NN cord-015369-72cjogxz 4633 4 palsy palsy NN cord-015369-72cjogxz 4633 5 rate rate NN cord-015369-72cjogxz 4633 6 by by IN cord-015369-72cjogxz 4633 7 using use VBG cord-015369-72cjogxz 4633 8 IONM IONM NNP cord-015369-72cjogxz 4633 9 . . . cord-015369-72cjogxz 4634 1 IONM IONM NNP cord-015369-72cjogxz 4634 2 decreases decrease VBZ cord-015369-72cjogxz 4634 3 the the DT cord-015369-72cjogxz 4634 4 transient transient JJ cord-015369-72cjogxz 4634 5 and and CC cord-015369-72cjogxz 4634 6 permanent permanent JJ cord-015369-72cjogxz 4634 7 recurrent recurrent JJ cord-015369-72cjogxz 4634 8 laryngeal laryngeal JJ cord-015369-72cjogxz 4634 9 nerve nerve NN cord-015369-72cjogxz 4634 10 palsy palsy NN cord-015369-72cjogxz 4634 11 rate rate NN cord-015369-72cjogxz 4634 12 in in IN cord-015369-72cjogxz 4634 13 reoperative reoperative JJ cord-015369-72cjogxz 4634 14 thyroid thyroid NN cord-015369-72cjogxz 4634 15 surgery surgery NN cord-015369-72cjogxz 4634 16 and and CC cord-015369-72cjogxz 4634 17 should should MD cord-015369-72cjogxz 4634 18 therefore therefore RB cord-015369-72cjogxz 4634 19 be be VB cord-015369-72cjogxz 4634 20 mandatory mandatory JJ cord-015369-72cjogxz 4634 21 . . . cord-015369-72cjogxz 4635 1 Das Das NNP cord-015369-72cjogxz 4635 2 intraoperative intraoperative JJ cord-015369-72cjogxz 4635 3 Neuromonitoring Neuromonitoring NNP cord-015369-72cjogxz 4635 4 ( ( -LRB- cord-015369-72cjogxz 4635 5 IONM IONM NNP cord-015369-72cjogxz 4635 6 ) ) -RRB- cord-015369-72cjogxz 4635 7 wird wird NNP cord-015369-72cjogxz 4635 8 bereits bereits NNPS cord-015369-72cjogxz 4635 9 in in IN cord-015369-72cjogxz 4635 10 zahlreichen zahlreichen NNP cord-015369-72cjogxz 4635 11 Kliniken Kliniken NNP cord-015369-72cjogxz 4635 12 zur zur NNP cord-015369-72cjogxz 4636 1 Identifikation Identifikation NNP cord-015369-72cjogxz 4636 2 des des NNP cord-015369-72cjogxz 4636 3 N. N. NNP cord-015369-72cjogxz 4636 4 laryngeus laryngeus NNP cord-015369-72cjogxz 4636 5 recurrens recurrens NNP cord-015369-72cjogxz 4636 6 ( ( -LRB- cord-015369-72cjogxz 4636 7 NLR NLR NNP cord-015369-72cjogxz 4636 8 ) ) -RRB- cord-015369-72cjogxz 4636 9 eingesetzt eingesetzt VBD cord-015369-72cjogxz 4636 10 . . . cord-015369-72cjogxz 4637 1 Während Während NNP cord-015369-72cjogxz 4637 2 der der NNP cord-015369-72cjogxz 4637 3 der der NNP cord-015369-72cjogxz 4637 4 Präparation Präparation NNP cord-015369-72cjogxz 4637 5 ist ist NN cord-015369-72cjogxz 4637 6 die die VBP cord-015369-72cjogxz 4637 7 Funktionsüberprüfung Funktionsüberprüfung NNP cord-015369-72cjogxz 4637 8 des des FW cord-015369-72cjogxz 4637 9 Nerven Nerven NNP cord-015369-72cjogxz 4637 10 nur nur NNP cord-015369-72cjogxz 4637 11 punktuell punktuell JJ cord-015369-72cjogxz 4637 12 möglich möglich NNP cord-015369-72cjogxz 4637 13 . . . cord-015369-72cjogxz 4638 1 Methodik Methodik NNP cord-015369-72cjogxz 4638 2 . . . cord-015369-72cjogxz 4639 1 Eine Eine NNP cord-015369-72cjogxz 4639 2 neu neu NNP cord-015369-72cjogxz 4639 3 entwickelte entwickelte NNP cord-015369-72cjogxz 4640 1 Vagussonde Vagussonde NNP cord-015369-72cjogxz 4640 2 ( ( -LRB- cord-015369-72cjogxz 4640 3 V3 v3 NN cord-015369-72cjogxz 4640 4 ; ; : cord-015369-72cjogxz 4640 5 Fa Fa NNP cord-015369-72cjogxz 4640 6 . . . cord-015369-72cjogxz 4641 1 Inomed Inomed NNP cord-015369-72cjogxz 4641 2 . . . cord-015369-72cjogxz 4642 1 Teningen Teningen NNP cord-015369-72cjogxz 4642 2 , , , cord-015369-72cjogxz 4642 3 Deutschland Deutschland NNP cord-015369-72cjogxz 4642 4 ) ) -RRB- cord-015369-72cjogxz 4642 5 wird wird NNP cord-015369-72cjogxz 4643 1 vor vor NNP cord-015369-72cjogxz 4643 2 der der NNP cord-015369-72cjogxz 4643 3 Präparation Präparation NNP cord-015369-72cjogxz 4643 4 der der NNP cord-015369-72cjogxz 4643 5 Grenzlamelle Grenzlamelle NNP cord-015369-72cjogxz 4643 6 in in IN cord-015369-72cjogxz 4643 7 der der NNP cord-015369-72cjogxz 4643 8 Gefäßnervenscheide Gefäßnervenscheide NNP cord-015369-72cjogxz 4644 1 zwischen zwischen NNP cord-015369-72cjogxz 4644 2 der der NNP cord-015369-72cjogxz 4644 3 A. A. NNP cord-015369-72cjogxz 4644 4 carotis carotis NNP cord-015369-72cjogxz 4644 5 und und NNP cord-015369-72cjogxz 4644 6 der der NNP cord-015369-72cjogxz 4644 7 V. V. NNP cord-015369-72cjogxz 4644 8 jugularis jugularis NNP cord-015369-72cjogxz 4644 9 in in IN cord-015369-72cjogxz 4644 10 engem engem NNP cord-015369-72cjogxz 4645 1 Kontakt Kontakt NNP cord-015369-72cjogxz 4645 2 zum zum NNP cord-015369-72cjogxz 4645 3 N. N. NNP cord-015369-72cjogxz 4645 4 vagus vagus NNP cord-015369-72cjogxz 4645 5 platziert platziert NNP cord-015369-72cjogxz 4645 6 . . . cord-015369-72cjogxz 4646 1 Die die VB cord-015369-72cjogxz 4646 2 Schwellenwerte Schwellenwerte NNP cord-015369-72cjogxz 4646 3 bis bis NNP cord-015369-72cjogxz 4646 4 zur zur NNP cord-015369-72cjogxz 4646 5 maximalen maximalen NNP cord-015369-72cjogxz 4647 1 Signalstärke Signalstärke NNP cord-015369-72cjogxz 4647 2 der der NN cord-015369-72cjogxz 4647 3 Ableitungen Ableitungen NNP cord-015369-72cjogxz 4647 4 über über NNP cord-015369-72cjogxz 4647 5 die die VBP cord-015369-72cjogxz 4647 6 Tubuselektrode Tubuselektrode NNP cord-015369-72cjogxz 4647 7 werden werden NNP cord-015369-72cjogxz 4647 8 zu zu NNP cord-015369-72cjogxz 4647 9 Beginn Beginn NNP cord-015369-72cjogxz 4648 1 und und IN cord-015369-72cjogxz 4648 2 am be VBP cord-015369-72cjogxz 4648 3 Ende Ende NNP cord-015369-72cjogxz 4648 4 der der NNP cord-015369-72cjogxz 4648 5 Operation Operation NNP cord-015369-72cjogxz 4648 6 ermittelt ermittelt NNS cord-015369-72cjogxz 4648 7 . . . cord-015369-72cjogxz 4649 1 Die die VB cord-015369-72cjogxz 4649 2 Stimulation stimulation NN cord-015369-72cjogxz 4649 3 erfolgt erfolgt NN cord-015369-72cjogxz 4649 4 mit mit JJ cord-015369-72cjogxz 4649 5 einer einer NNP cord-015369-72cjogxz 4649 6 Frequenz Frequenz NNP cord-015369-72cjogxz 4649 7 von von NNP cord-015369-72cjogxz 4650 1 3 3 LS cord-015369-72cjogxz 4650 2 Hz Hz NNP cord-015369-72cjogxz 4650 3 und und IN cord-015369-72cjogxz 4650 4 einer einer NNP cord-015369-72cjogxz 4650 5 Stromstärke Stromstärke NNP cord-015369-72cjogxz 4650 6 unterhalb unterhalb NNP cord-015369-72cjogxz 4650 7 der der NNP cord-015369-72cjogxz 4650 8 maximalen maximalen NNP cord-015369-72cjogxz 4650 9 Signalantwort Signalantwort NNP cord-015369-72cjogxz 4650 10 . . . cord-015369-72cjogxz 4651 1 Die die VB cord-015369-72cjogxz 4652 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4652 2 einer einer NNP cord-015369-72cjogxz 4653 1 konsekutiven konsekutiven NNP cord-015369-72cjogxz 4654 1 Serie Serie NNP cord-015369-72cjogxz 4654 2 von von NNP cord-015369-72cjogxz 4654 3 30 30 CD cord-015369-72cjogxz 4654 4 beidseitigen beidseitigen NNP cord-015369-72cjogxz 4654 5 Resektionen Resektionen NNP cord-015369-72cjogxz 4654 6 ( ( -LRB- cord-015369-72cjogxz 4654 7 n n NN cord-015369-72cjogxz 4654 8 ¼ ¼ CD cord-015369-72cjogxz 4654 9 60 60 CD cord-015369-72cjogxz 4654 10 nerves nerve NNS cord-015369-72cjogxz 4654 11 at at IN cord-015369-72cjogxz 4654 12 risk risk NN cord-015369-72cjogxz 4654 13 ) ) -RRB- cord-015369-72cjogxz 4654 14 werden werden NNP cord-015369-72cjogxz 4654 15 dargestellt dargestellt NNP cord-015369-72cjogxz 4654 16 . . . cord-015369-72cjogxz 4655 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4655 2 . . . cord-015369-72cjogxz 4656 1 Der Der NNP cord-015369-72cjogxz 4656 2 Schwellenwert Schwellenwert NNP cord-015369-72cjogxz 4656 3 zur zur NNP cord-015369-72cjogxz 4656 4 supramaximalen supramaximalen NNP cord-015369-72cjogxz 4656 5 Stimulation stimulation NN cord-015369-72cjogxz 4656 6 lag lag HYPH cord-015369-72cjogxz 4656 7 zwischen zwischen NNP cord-015369-72cjogxz 4656 8 2,5 2,5 CD cord-015369-72cjogxz 4656 9 und und NN cord-015369-72cjogxz 4656 10 4 4 CD cord-015369-72cjogxz 4657 1 mA. mA. NNP cord-015369-72cjogxz 4657 2 Diese Diese NNP cord-015369-72cjogxz 4657 3 Werte Werte NNP cord-015369-72cjogxz 4657 4 unterschieden unterschieden JJ cord-015369-72cjogxz 4657 5 am be VBP cord-015369-72cjogxz 4657 6 Beginn Beginn NNP cord-015369-72cjogxz 4658 1 und und IN cord-015369-72cjogxz 4658 2 am be VBP cord-015369-72cjogxz 4658 3 Ender Ender NNP cord-015369-72cjogxz 4658 4 der der NNP cord-015369-72cjogxz 4658 5 Operation Operation NNP cord-015369-72cjogxz 4659 1 um um UH cord-015369-72cjogxz 4659 2 maximal maximal JJ cord-015369-72cjogxz 4659 3 0,5 0,5 CD cord-015369-72cjogxz 4660 1 mA. mA. NNP cord-015369-72cjogxz 4660 2 Passagere Passagere NNP cord-015369-72cjogxz 4660 3 Recurrensparesen Recurrensparesen NNP cord-015369-72cjogxz 4660 4 wurden wurden VBD cord-015369-72cjogxz 4660 5 in in IN cord-015369-72cjogxz 4660 6 2 2 CD cord-015369-72cjogxz 4660 7 Fällen Fällen NNP cord-015369-72cjogxz 4660 8 beobachtet beobachtet NNP cord-015369-72cjogxz 4660 9 . . . cord-015369-72cjogxz 4661 1 In in IN cord-015369-72cjogxz 4661 2 beiden beiden NNP cord-015369-72cjogxz 4661 3 Fällen Fällen NNP cord-015369-72cjogxz 4661 4 fiel fiel NNP cord-015369-72cjogxz 4661 5 während während NNP cord-015369-72cjogxz 4661 6 der der NNP cord-015369-72cjogxz 4661 7 Präparation Präparation NNP cord-015369-72cjogxz 4661 8 das das NNP cord-015369-72cjogxz 4661 9 Signal Signal NNP cord-015369-72cjogxz 4661 10 des des FW cord-015369-72cjogxz 4661 11 kontinuierlichen kontinuierlichen FW cord-015369-72cjogxz 4661 12 IONM IONM NNP cord-015369-72cjogxz 4661 13 aus aus NNP cord-015369-72cjogxz 4661 14 , , , cord-015369-72cjogxz 4661 15 die die VB cord-015369-72cjogxz 4661 16 Schädigungsstelle Schädigungsstelle NNP cord-015369-72cjogxz 4661 17 konnte konnte NNP cord-015369-72cjogxz 4661 18 bei bei NNP cord-015369-72cjogxz 4661 19 erhaltener erhaltener NNP cord-015369-72cjogxz 4661 20 Kontinuität Kontinuität NNP cord-015369-72cjogxz 4661 21 des des FW cord-015369-72cjogxz 4661 22 Nerven Nerven NNP cord-015369-72cjogxz 4661 23 exakt exakt NNP cord-015369-72cjogxz 4661 24 lokalisiert lokalisiert NNP cord-015369-72cjogxz 4661 25 werden werden NNP cord-015369-72cjogxz 4661 26 . . . cord-015369-72cjogxz 4662 1 In in IN cord-015369-72cjogxz 4662 2 beiden beiden NNP cord-015369-72cjogxz 4663 1 Fällen Fällen NNP cord-015369-72cjogxz 4663 2 zeigte zeigte NNP cord-015369-72cjogxz 4663 3 sich sich NNP cord-015369-72cjogxz 4663 4 ein ein NNP cord-015369-72cjogxz 4663 5 Stimmbandstillstand Stimmbandstillstand NNP cord-015369-72cjogxz 4663 6 unmittelbar unmittelbar NN cord-015369-72cjogxz 4663 7 postoperativ postoperativ NNP cord-015369-72cjogxz 4663 8 , , , cord-015369-72cjogxz 4663 9 eine eine NNP cord-015369-72cjogxz 4663 10 vollständige vollständige NNP cord-015369-72cjogxz 4663 11 Wiederherstellung Wiederherstellung NNP cord-015369-72cjogxz 4663 12 der der NNP cord-015369-72cjogxz 4664 1 Beweglichkeit Beweglichkeit NNP cord-015369-72cjogxz 4664 2 nach nach NNP cord-015369-72cjogxz 4664 3 2 2 CD cord-015369-72cjogxz 4665 1 Tagen Tagen NNP cord-015369-72cjogxz 4665 2 und und IN cord-015369-72cjogxz 4665 3 2 2 CD cord-015369-72cjogxz 4665 4 Wochen Wochen NNP cord-015369-72cjogxz 4665 5 . . . cord-015369-72cjogxz 4666 1 Die die VB cord-015369-72cjogxz 4667 1 Stimulationsdauer Stimulationsdauer NNP cord-015369-72cjogxz 4667 2 des des NNP cord-015369-72cjogxz 4668 1 einzelnen einzelnen NNP cord-015369-72cjogxz 4668 2 Nerven Nerven NNP cord-015369-72cjogxz 4668 3 lag lag VBP cord-015369-72cjogxz 4668 4 intraoperativ intraoperativ NNP cord-015369-72cjogxz 4668 5 zwischen zwischen NNP cord-015369-72cjogxz 4668 6 9 9 CD cord-015369-72cjogxz 4668 7 und und CD cord-015369-72cjogxz 4668 8 23 23 CD cord-015369-72cjogxz 4668 9 Minuten Minuten NNP cord-015369-72cjogxz 4668 10 . . . cord-015369-72cjogxz 4669 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4669 2 . . . cord-015369-72cjogxz 4670 1 Das Das NNP cord-015369-72cjogxz 4670 2 kontinuierliche kontinuierliche NNP cord-015369-72cjogxz 4670 3 IONM IONM NNP cord-015369-72cjogxz 4670 4 scheint scheint NNP cord-015369-72cjogxz 4670 5 Störungen Störungen NNP cord-015369-72cjogxz 4670 6 der der NNP cord-015369-72cjogxz 4670 7 Leitfähigkeit Leitfähigkeit NNP cord-015369-72cjogxz 4670 8 des des FW cord-015369-72cjogxz 4670 9 NLR NLR NNP cord-015369-72cjogxz 4670 10 sehr sehr NNP cord-015369-72cjogxz 4670 11 empfindlich empfindlich NNP cord-015369-72cjogxz 4670 12 anzuzeigen anzuzeigen NNP cord-015369-72cjogxz 4670 13 . . . cord-015369-72cjogxz 4671 1 Konsequenzen Konsequenzen NNS cord-015369-72cjogxz 4671 2 für für RB cord-015369-72cjogxz 4671 3 die die VBP cord-015369-72cjogxz 4671 4 Operationstaktik Operationstaktik NNP cord-015369-72cjogxz 4671 5 müssen müssen NNP cord-015369-72cjogxz 4671 6 in in IN cord-015369-72cjogxz 4671 7 weiteren weiteren NNP cord-015369-72cjogxz 4671 8 Anwendungen Anwendungen NNP cord-015369-72cjogxz 4671 9 evaluiert evaluiert NNP cord-015369-72cjogxz 4671 10 werden werden NNP cord-015369-72cjogxz 4671 11 . . . cord-015369-72cjogxz 4672 1 Aspekte Aspekte NNP cord-015369-72cjogxz 4672 2 der der NNP cord-015369-72cjogxz 4672 3 Sicherheit Sicherheit NNP cord-015369-72cjogxz 4672 4 für für IN cord-015369-72cjogxz 4672 5 den den NNP cord-015369-72cjogxz 4672 6 motorischen motorischen NNP cord-015369-72cjogxz 4672 7 Nerven Nerven NNP cord-015369-72cjogxz 4672 8 durch durch NNP cord-015369-72cjogxz 4672 9 eine eine NNP cord-015369-72cjogxz 4672 10 elektrische elektrische NN cord-015369-72cjogxz 4672 11 Dauerstimulation Dauerstimulation NNP cord-015369-72cjogxz 4672 12 werden werden NNP cord-015369-72cjogxz 4672 13 diskutiert diskutiert NNP cord-015369-72cjogxz 4672 14 . . . cord-015369-72cjogxz 4673 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4673 2 . . . cord-015369-72cjogxz 4674 1 Diagnostik Diagnostik NNP cord-015369-72cjogxz 4674 2 und und IN cord-015369-72cjogxz 4674 3 Therapie Therapie NNP cord-015369-72cjogxz 4674 4 der der NNP cord-015369-72cjogxz 4674 5 Choledocholithiasis Choledocholithiasis NNP cord-015369-72cjogxz 4674 6 werden werden NNP cord-015369-72cjogxz 4674 7 in in IN cord-015369-72cjogxz 4674 8 der der NNP cord-015369-72cjogxz 4674 9 Ä Ä NNP cord-015369-72cjogxz 4674 10 ra ra NN cord-015369-72cjogxz 4675 1 der der NNP cord-015369-72cjogxz 4675 2 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 4676 1 Cholecystektomie Cholecystektomie NNP cord-015369-72cjogxz 4676 2 unterschiedlich unterschiedlich JJ cord-015369-72cjogxz 4676 3 gehandhabt gehandhabt VBN cord-015369-72cjogxz 4676 4 . . . cord-015369-72cjogxz 4677 1 An an DT cord-015369-72cjogxz 4677 2 unserer unserer JJ cord-015369-72cjogxz 4677 3 Abteilung Abteilung NNP cord-015369-72cjogxz 4677 4 sind sind NNP cord-015369-72cjogxz 4677 5 Indikation Indikation NNP cord-015369-72cjogxz 4677 6 und und IN cord-015369-72cjogxz 4677 7 Zeitpunkt Zeitpunkt NNP cord-015369-72cjogxz 4677 8 der der NNP cord-015369-72cjogxz 4677 9 ERCP/ ERCP/ NNP cord-015369-72cjogxz 4678 1 EPT EPT NNP cord-015369-72cjogxz 4678 2 abhängig abhängig NNP cord-015369-72cjogxz 4678 3 von von NNP cord-015369-72cjogxz 4678 4 Anamnese Anamnese NNP cord-015369-72cjogxz 4678 5 , , , cord-015369-72cjogxz 4678 6 Labor Labor NNP cord-015369-72cjogxz 4678 7 , , , cord-015369-72cjogxz 4678 8 Sonographie Sonographie NNP cord-015369-72cjogxz 4678 9 und und IN cord-015369-72cjogxz 4678 10 routinemäßiger routinemäßiger NNP cord-015369-72cjogxz 4678 11 intraoperativer intraoperativer NNP cord-015369-72cjogxz 4678 12 Cholangiographie Cholangiographie NNP cord-015369-72cjogxz 4678 13 . . . cord-015369-72cjogxz 4679 1 Methodik Methodik NNP cord-015369-72cjogxz 4679 2 . . . cord-015369-72cjogxz 4680 1 Zwischen Zwischen NNP cord-015369-72cjogxz 4680 2 1 1 CD cord-015369-72cjogxz 4680 3 . . . cord-015369-72cjogxz 4681 1 1.2003 1.2003 CD cord-015369-72cjogxz 4681 2 und und IN cord-015369-72cjogxz 4681 3 31.12.2008 31.12.2008 CD cord-015369-72cjogxz 4681 4 wurden wurden VBD cord-015369-72cjogxz 4681 5 an an DT cord-015369-72cjogxz 4681 6 unserer unserer JJ cord-015369-72cjogxz 4681 7 Abteilung Abteilung NNP cord-015369-72cjogxz 4681 8 1015 1015 CD cord-015369-72cjogxz 4681 9 laparoskopische laparoskopische NNP cord-015369-72cjogxz 4681 10 Cholecystektomien Cholecystektomien NNP cord-015369-72cjogxz 4681 11 ( ( -LRB- cord-015369-72cjogxz 4681 12 83,1 83,1 CD cord-015369-72cjogxz 4681 13 % % NN cord-015369-72cjogxz 4681 14 aller aller NNP cord-015369-72cjogxz 4681 15 Galleneingriffe Galleneingriffe NNP cord-015369-72cjogxz 4681 16 ) ) -RRB- cord-015369-72cjogxz 4681 17 durchgeführt durchgeführt NN cord-015369-72cjogxz 4681 18 . . . cord-015369-72cjogxz 4682 1 Bei Bei NNP cord-015369-72cjogxz 4682 2 178 178 CD cord-015369-72cjogxz 4683 1 dieser dieser NNP cord-015369-72cjogxz 4683 2 Patienten Patienten NNP cord-015369-72cjogxz 4683 3 ( ( -LRB- cord-015369-72cjogxz 4683 4 17,5 17,5 CD cord-015369-72cjogxz 4683 5 % % NN cord-015369-72cjogxz 4683 6 ) ) -RRB- cord-015369-72cjogxz 4684 1 wurde wurde NNP cord-015369-72cjogxz 4685 1 auch auch NNP cord-015369-72cjogxz 4685 2 eine eine NNP cord-015369-72cjogxz 4685 3 Choledochuspathologie Choledochuspathologie NNP cord-015369-72cjogxz 4685 4 ( ( -LRB- cord-015369-72cjogxz 4685 5 Papillenstenose Papillenstenose NNP cord-015369-72cjogxz 4685 6 , , , cord-015369-72cjogxz 4685 7 Choledocholithiasis Choledocholithiasis NNP cord-015369-72cjogxz 4685 8 ) ) -RRB- cord-015369-72cjogxz 4685 9 diagnostiziert diagnostiziert NNP cord-015369-72cjogxz 4686 1 und und NNP cord-015369-72cjogxz 4687 1 prae- prae- NNP cord-015369-72cjogxz 4687 2 , , , cord-015369-72cjogxz 4687 3 intra intra NNP cord-015369-72cjogxz 4687 4 - - JJ cord-015369-72cjogxz 4687 5 oder oder JJ cord-015369-72cjogxz 4687 6 postoperativ postoperativ JJ cord-015369-72cjogxz 4687 7 mittels mittels NNP cord-015369-72cjogxz 4687 8 ERCP ERCP NNP cord-015369-72cjogxz 4687 9 / / SYM cord-015369-72cjogxz 4687 10 EPT EPT NNP cord-015369-72cjogxz 4687 11 behandelt behandelt NNP cord-015369-72cjogxz 4687 12 . . . cord-015369-72cjogxz 4688 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4688 2 . . . cord-015369-72cjogxz 4689 1 In in IN cord-015369-72cjogxz 4689 2 unserem unserem NNP cord-015369-72cjogxz 4689 3 Krankengut Krankengut NNP cord-015369-72cjogxz 4689 4 hat hat NN cord-015369-72cjogxz 4689 5 sich sich XX cord-015369-72cjogxz 4689 6 die die VBP cord-015369-72cjogxz 4689 7 prae- prae- NNP cord-015369-72cjogxz 4689 8 , , , cord-015369-72cjogxz 4689 9 intra intra JJ cord-015369-72cjogxz 4689 10 - - HYPH cord-015369-72cjogxz 4689 11 und und JJ cord-015369-72cjogxz 4689 12 postoperative postoperative JJ cord-015369-72cjogxz 4689 13 ERCP/ ercp/ XX cord-015369-72cjogxz 4690 1 EPT EPT NNP cord-015369-72cjogxz 4691 1 i i PRP cord-015369-72cjogxz 4692 1 m m LS cord-015369-72cjogxz 4693 1 Rahmen Rahmen NNP cord-015369-72cjogxz 4693 2 der der NNP cord-015369-72cjogxz 4693 3 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 4693 4 Cholecystektomie Cholecystektomie NNP cord-015369-72cjogxz 4693 5 bei bei NNP cord-015369-72cjogxz 4693 6 Cholecysto Cholecysto NNP cord-015369-72cjogxz 4693 7 - - HYPH cord-015369-72cjogxz 4693 8 und und NNP cord-015369-72cjogxz 4693 9 Choledocholithiasis Choledocholithiasis NNP cord-015369-72cjogxz 4693 10 sehr sehr JJ cord-015369-72cjogxz 4693 11 bewährt bewährt NN cord-015369-72cjogxz 4693 12 . . . cord-015369-72cjogxz 4694 1 Die die VB cord-015369-72cjogxz 4694 2 routinemäßige routinemäßige NNP cord-015369-72cjogxz 4694 3 intraoperative intraoperative JJ cord-015369-72cjogxz 4694 4 Cholangiographie Cholangiographie NNP cord-015369-72cjogxz 4694 5 führte führte NN cord-015369-72cjogxz 4694 6 bei bei NNP cord-015369-72cjogxz 4694 7 4,4 4,4 CD cord-015369-72cjogxz 4694 8 % % NN cord-015369-72cjogxz 4695 1 der der NNP cord-015369-72cjogxz 4695 2 Patienten Patienten NNP cord-015369-72cjogxz 4695 3 zur zur NNP cord-015369-72cjogxz 4695 4 Diagnose diagnose VBP cord-015369-72cjogxz 4695 5 und und IN cord-015369-72cjogxz 4695 6 Therapie Therapie NNP cord-015369-72cjogxz 4695 7 unerwarteter unerwarteter NN cord-015369-72cjogxz 4695 8 Choledochuskonkremente Choledochuskonkremente NNP cord-015369-72cjogxz 4695 9 ! ! . cord-015369-72cjogxz 4696 1 Randomized randomized JJ cord-015369-72cjogxz 4696 2 controlled control VBN cord-015369-72cjogxz 4696 3 trial trial NN cord-015369-72cjogxz 4696 4 to to TO cord-015369-72cjogxz 4696 5 assess assess VB cord-015369-72cjogxz 4696 6 feasibility feasibility NN cord-015369-72cjogxz 4696 7 and and CC cord-015369-72cjogxz 4696 8 efficacy efficacy NN cord-015369-72cjogxz 4696 9 of of IN cord-015369-72cjogxz 4696 10 CO co NN cord-015369-72cjogxz 4696 11 2 2 CD cord-015369-72cjogxz 4696 12 insufflation insufflation NN cord-015369-72cjogxz 4696 13 during during IN cord-015369-72cjogxz 4696 14 colonoscopy colonoscopy NN cord-015369-72cjogxz 4696 15 in in IN cord-015369-72cjogxz 4696 16 moderate moderate JJ cord-015369-72cjogxz 4696 17 and and CC cord-015369-72cjogxz 4696 18 deep deep JJ cord-015369-72cjogxz 4696 19 sedated sedated JJ cord-015369-72cjogxz 4696 20 patients patient NNS cord-015369-72cjogxz 4696 21 Background Background NNP cord-015369-72cjogxz 4696 22 . . . cord-015369-72cjogxz 4697 1 Air air NN cord-015369-72cjogxz 4697 2 insufflation insufflation NN cord-015369-72cjogxz 4697 3 during during IN cord-015369-72cjogxz 4697 4 colonoscopy colonoscopy NN cord-015369-72cjogxz 4697 5 is be VBZ cord-015369-72cjogxz 4697 6 the the DT cord-015369-72cjogxz 4697 7 considered consider VBN cord-015369-72cjogxz 4697 8 standard standard JJ cord-015369-72cjogxz 4697 9 method method NN cord-015369-72cjogxz 4697 10 in in IN cord-015369-72cjogxz 4697 11 most most JJS cord-015369-72cjogxz 4697 12 endoscopic endoscopic JJ cord-015369-72cjogxz 4697 13 centers center NNS cord-015369-72cjogxz 4697 14 . . . cord-015369-72cjogxz 4698 1 Notably notably RB cord-015369-72cjogxz 4698 2 , , , cord-015369-72cjogxz 4698 3 several several JJ cord-015369-72cjogxz 4698 4 studies study NNS cord-015369-72cjogxz 4698 5 reported report VBD cord-015369-72cjogxz 4698 6 reduced reduce VBN cord-015369-72cjogxz 4698 7 abdominal abdominal JJ cord-015369-72cjogxz 4698 8 pain pain NN cord-015369-72cjogxz 4698 9 during during IN cord-015369-72cjogxz 4698 10 and and CC cord-015369-72cjogxz 4698 11 after after IN cord-015369-72cjogxz 4698 12 colonoscopy colonoscopy NN cord-015369-72cjogxz 4698 13 by by IN cord-015369-72cjogxz 4698 14 using use VBG cord-015369-72cjogxz 4698 15 CO co NN cord-015369-72cjogxz 4698 16 2 2 CD cord-015369-72cjogxz 4698 17 insufflation insufflation NN cord-015369-72cjogxz 4698 18 in in IN cord-015369-72cjogxz 4698 19 unsedated unsedated JJ cord-015369-72cjogxz 4698 20 as as RB cord-015369-72cjogxz 4698 21 well well RB cord-015369-72cjogxz 4698 22 as as IN cord-015369-72cjogxz 4698 23 light light JJ cord-015369-72cjogxz 4698 24 sedated sedated JJ cord-015369-72cjogxz 4698 25 patients patient NNS cord-015369-72cjogxz 4698 26 . . . cord-015369-72cjogxz 4699 1 The the DT cord-015369-72cjogxz 4699 2 study study NN cord-015369-72cjogxz 4699 3 was be VBD cord-015369-72cjogxz 4699 4 designed design VBN cord-015369-72cjogxz 4699 5 to to TO cord-015369-72cjogxz 4699 6 assess assess VB cord-015369-72cjogxz 4699 7 the the DT cord-015369-72cjogxz 4699 8 feasibility feasibility NN cord-015369-72cjogxz 4699 9 and and CC cord-015369-72cjogxz 4699 10 efficacy efficacy NN cord-015369-72cjogxz 4699 11 of of IN cord-015369-72cjogxz 4699 12 CO CO NNP cord-015369-72cjogxz 4699 13 2 2 CD cord-015369-72cjogxz 4699 14 during during IN cord-015369-72cjogxz 4699 15 and and CC cord-015369-72cjogxz 4699 16 after after IN cord-015369-72cjogxz 4699 17 colonoscopy colonoscopy NN cord-015369-72cjogxz 4699 18 in in IN cord-015369-72cjogxz 4699 19 moderate moderate JJ cord-015369-72cjogxz 4699 20 and and CC cord-015369-72cjogxz 4699 21 deep deep JJ cord-015369-72cjogxz 4699 22 sedated sedated JJ cord-015369-72cjogxz 4699 23 patients patient NNS cord-015369-72cjogxz 4699 24 . . . cord-015369-72cjogxz 4700 1 The the DT cord-015369-72cjogxz 4700 2 secondary secondary JJ cord-015369-72cjogxz 4700 3 endpoint endpoint NN cord-015369-72cjogxz 4700 4 was be VBD cord-015369-72cjogxz 4700 5 to to TO cord-015369-72cjogxz 4700 6 evaluate evaluate VB cord-015369-72cjogxz 4700 7 whether whether IN cord-015369-72cjogxz 4700 8 CO CO NNP cord-015369-72cjogxz 4700 9 2 2 CD cord-015369-72cjogxz 4700 10 is be VBZ cord-015369-72cjogxz 4700 11 able able JJ cord-015369-72cjogxz 4700 12 to to TO cord-015369-72cjogxz 4700 13 enhance enhance VB cord-015369-72cjogxz 4700 14 patient patient NN cord-015369-72cjogxz 4700 15 's 's POS cord-015369-72cjogxz 4700 16 compliance compliance NN cord-015369-72cjogxz 4700 17 to to TO cord-015369-72cjogxz 4700 18 undergo undergo VB cord-015369-72cjogxz 4700 19 colonic colonic JJ cord-015369-72cjogxz 4700 20 cancer cancer NN cord-015369-72cjogxz 4700 21 screening screening NN cord-015369-72cjogxz 4700 22 . . . cord-015369-72cjogxz 4701 1 Methods method NNS cord-015369-72cjogxz 4701 2 . . . cord-015369-72cjogxz 4702 1 Three three CD cord-015369-72cjogxz 4702 2 - - HYPH cord-015369-72cjogxz 4702 3 hundred hundred CD cord-015369-72cjogxz 4702 4 consecutive consecutive JJ cord-015369-72cjogxz 4702 5 patients patient NNS cord-015369-72cjogxz 4702 6 allocated allocate VBN cord-015369-72cjogxz 4702 7 for for IN cord-015369-72cjogxz 4702 8 colonoscopy colonoscopy NN cord-015369-72cjogxz 4702 9 were be VBD cord-015369-72cjogxz 4702 10 randomly randomly RB cord-015369-72cjogxz 4702 11 assigned assign VBN cord-015369-72cjogxz 4702 12 to to IN cord-015369-72cjogxz 4702 13 either either CC cord-015369-72cjogxz 4702 14 CO CO NNP cord-015369-72cjogxz 4702 15 2 2 CD cord-015369-72cjogxz 4702 16 or or CC cord-015369-72cjogxz 4702 17 air air NN cord-015369-72cjogxz 4702 18 insufflation insufflation NN cord-015369-72cjogxz 4702 19 . . . cord-015369-72cjogxz 4703 1 Patients patient NNS cord-015369-72cjogxz 4703 2 were be VBD cord-015369-72cjogxz 4703 3 titrated titrate VBN cord-015369-72cjogxz 4703 4 to to IN cord-015369-72cjogxz 4703 5 a a DT cord-015369-72cjogxz 4703 6 level level NN cord-015369-72cjogxz 4703 7 of of IN cord-015369-72cjogxz 4703 8 deep deep JJ cord-015369-72cjogxz 4703 9 sedation sedation NN cord-015369-72cjogxz 4703 10 by by IN cord-015369-72cjogxz 4703 11 propofol propofol NN cord-015369-72cjogxz 4703 12 alone alone RB cord-015369-72cjogxz 4703 13 or or CC cord-015369-72cjogxz 4703 14 to to TO cord-015369-72cjogxz 4703 15 moderate moderate JJ cord-015369-72cjogxz 4703 16 sedation sedation NN cord-015369-72cjogxz 4703 17 when when WRB cord-015369-72cjogxz 4703 18 combined combine VBN cord-015369-72cjogxz 4703 19 with with IN cord-015369-72cjogxz 4703 20 midazolam midazolam NNP cord-015369-72cjogxz 4703 21 . . . cord-015369-72cjogxz 4704 1 Postinterventional postinterventional JJ cord-015369-72cjogxz 4704 2 pain pain NN cord-015369-72cjogxz 4704 3 and and CC cord-015369-72cjogxz 4704 4 satisfaction satisfaction NN cord-015369-72cjogxz 4704 5 were be VBD cord-015369-72cjogxz 4704 6 registered register VBN cord-015369-72cjogxz 4704 7 by by IN cord-015369-72cjogxz 4704 8 a a DT cord-015369-72cjogxz 4704 9 visual visual JJ cord-015369-72cjogxz 4704 10 analogue analogue NN cord-015369-72cjogxz 4704 11 scale scale NN cord-015369-72cjogxz 4704 12 ( ( -LRB- cord-015369-72cjogxz 4704 13 VAS VAS NNP cord-015369-72cjogxz 4704 14 ) ) -RRB- cord-015369-72cjogxz 4704 15 . . . cord-015369-72cjogxz 4705 1 Colonic colonic JJ cord-015369-72cjogxz 4705 2 cancer cancer NN cord-015369-72cjogxz 4705 3 screening screening NN cord-015369-72cjogxz 4705 4 compliance compliance NN cord-015369-72cjogxz 4705 5 was be VBD cord-015369-72cjogxz 4705 6 questioned question VBN cord-015369-72cjogxz 4705 7 separately separately RB cord-015369-72cjogxz 4705 8 . . . cord-015369-72cjogxz 4706 1 Results result NNS cord-015369-72cjogxz 4706 2 . . . cord-015369-72cjogxz 4707 1 CO co NN cord-015369-72cjogxz 4707 2 2 2 CD cord-015369-72cjogxz 4707 3 insufflation insufflation NN cord-015369-72cjogxz 4707 4 was be VBD cord-015369-72cjogxz 4707 5 used use VBN cord-015369-72cjogxz 4707 6 in in IN cord-015369-72cjogxz 4707 7 157 157 CD cord-015369-72cjogxz 4707 8 patients patient NNS cord-015369-72cjogxz 4707 9 , , , cord-015369-72cjogxz 4707 10 whereas whereas IN cord-015369-72cjogxz 4707 11 in in IN cord-015369-72cjogxz 4707 12 143 143 CD cord-015369-72cjogxz 4707 13 patients patient NNS cord-015369-72cjogxz 4707 14 conventional conventional JJ cord-015369-72cjogxz 4707 15 air air NN cord-015369-72cjogxz 4707 16 was be VBD cord-015369-72cjogxz 4707 17 applied apply VBN cord-015369-72cjogxz 4707 18 during during IN cord-015369-72cjogxz 4707 19 colonoscopy colonoscopy NN cord-015369-72cjogxz 4707 20 . . . cord-015369-72cjogxz 4708 1 Both both DT cord-015369-72cjogxz 4708 2 groups group NNS cord-015369-72cjogxz 4708 3 were be VBD cord-015369-72cjogxz 4708 4 comparable comparable JJ cord-015369-72cjogxz 4708 5 in in IN cord-015369-72cjogxz 4708 6 regard regard NN cord-015369-72cjogxz 4708 7 to to IN cord-015369-72cjogxz 4708 8 age age NN cord-015369-72cjogxz 4708 9 , , , cord-015369-72cjogxz 4708 10 sex sex NN cord-015369-72cjogxz 4708 11 and and CC cord-015369-72cjogxz 4708 12 BMI BMI NNP cord-015369-72cjogxz 4708 13 . . . cord-015369-72cjogxz 4709 1 Neither neither DT cord-015369-72cjogxz 4709 2 major major JJ cord-015369-72cjogxz 4709 3 nor nor CC cord-015369-72cjogxz 4709 4 minor minor JJ cord-015369-72cjogxz 4709 5 complications complication NNS cord-015369-72cjogxz 4709 6 were be VBD cord-015369-72cjogxz 4709 7 observed observe VBN cord-015369-72cjogxz 4709 8 . . . cord-015369-72cjogxz 4710 1 Painsensation Painsensation NNP cord-015369-72cjogxz 4710 2 was be VBD cord-015369-72cjogxz 4710 3 significantly significantly RB cord-015369-72cjogxz 4710 4 lower low JJR cord-015369-72cjogxz 4710 5 in in IN cord-015369-72cjogxz 4710 6 the the DT cord-015369-72cjogxz 4710 7 CO co NN cord-015369-72cjogxz 4710 8 2 2 CD cord-015369-72cjogxz 4710 9 group group NN cord-015369-72cjogxz 4710 10 15 15 CD cord-015369-72cjogxz 4710 11 min min NN cord-015369-72cjogxz 4710 12 , , , cord-015369-72cjogxz 4710 13 30 30 CD cord-015369-72cjogxz 4710 14 min min NN cord-015369-72cjogxz 4710 15 as as RB cord-015369-72cjogxz 4710 16 well well RB cord-015369-72cjogxz 4710 17 as as IN cord-015369-72cjogxz 4710 18 6 6 CD cord-015369-72cjogxz 4710 19 h h NN cord-015369-72cjogxz 4710 20 after after IN cord-015369-72cjogxz 4710 21 colonoscopy colonoscopy NN cord-015369-72cjogxz 4710 22 ( ( -LRB- cord-015369-72cjogxz 4710 23 p p NN cord-015369-72cjogxz 4710 24 < < XX cord-015369-72cjogxz 4710 25 0.01 0.01 CD cord-015369-72cjogxz 4710 26 ) ) -RRB- cord-015369-72cjogxz 4710 27 . . . cord-015369-72cjogxz 4711 1 Twelve twelve CD cord-015369-72cjogxz 4711 2 hours hour NNS cord-015369-72cjogxz 4711 3 after after IN cord-015369-72cjogxz 4711 4 endoscopy endoscopy NN cord-015369-72cjogxz 4711 5 no no DT cord-015369-72cjogxz 4711 6 difference difference NN cord-015369-72cjogxz 4711 7 was be VBD cord-015369-72cjogxz 4711 8 observed observe VBN cord-015369-72cjogxz 4711 9 . . . cord-015369-72cjogxz 4712 1 In in IN cord-015369-72cjogxz 4712 2 contrast contrast NN cord-015369-72cjogxz 4712 3 , , , cord-015369-72cjogxz 4712 4 satisfaction satisfaction NN cord-015369-72cjogxz 4712 5 level level NN cord-015369-72cjogxz 4712 6 did do VBD cord-015369-72cjogxz 4712 7 not not RB cord-015369-72cjogxz 4712 8 show show VB cord-015369-72cjogxz 4712 9 any any DT cord-015369-72cjogxz 4712 10 significant significant JJ cord-015369-72cjogxz 4712 11 difference difference NN cord-015369-72cjogxz 4712 12 . . . cord-015369-72cjogxz 4713 1 Voluntary voluntary JJ cord-015369-72cjogxz 4713 2 colonic colonic JJ cord-015369-72cjogxz 4713 3 cancer cancer NN cord-015369-72cjogxz 4713 4 screening screening NN cord-015369-72cjogxz 4713 5 seemed seem VBD cord-015369-72cjogxz 4713 6 not not RB cord-015369-72cjogxz 4713 7 to to TO cord-015369-72cjogxz 4713 8 be be VB cord-015369-72cjogxz 4713 9 influenced influence VBN cord-015369-72cjogxz 4713 10 by by IN cord-015369-72cjogxz 4713 11 the the DT cord-015369-72cjogxz 4713 12 type type NN cord-015369-72cjogxz 4713 13 of of IN cord-015369-72cjogxz 4713 14 insufflation insufflation NN cord-015369-72cjogxz 4713 15 gas gas NN cord-015369-72cjogxz 4713 16 . . . cord-015369-72cjogxz 4714 1 Conclusions conclusion NNS cord-015369-72cjogxz 4714 2 . . . cord-015369-72cjogxz 4715 1 CO co NN cord-015369-72cjogxz 4715 2 2 2 CD cord-015369-72cjogxz 4715 3 insufflation insufflation NN cord-015369-72cjogxz 4715 4 in in IN cord-015369-72cjogxz 4715 5 deep deep JJ cord-015369-72cjogxz 4715 6 and and CC cord-015369-72cjogxz 4715 7 moderated moderate VBD cord-015369-72cjogxz 4715 8 sedated sedated JJ cord-015369-72cjogxz 4715 9 patients patient NNS cord-015369-72cjogxz 4715 10 during during IN cord-015369-72cjogxz 4715 11 colonoscopy colonoscopy NN cord-015369-72cjogxz 4715 12 significantly significantly RB cord-015369-72cjogxz 4715 13 reduced reduce VBN cord-015369-72cjogxz 4715 14 postinterventional postinterventional JJ cord-015369-72cjogxz 4715 15 abdominal abdominal JJ cord-015369-72cjogxz 4715 16 pain pain NN cord-015369-72cjogxz 4715 17 . . . cord-015369-72cjogxz 4716 1 Interestingly interestingly RB cord-015369-72cjogxz 4716 2 , , , cord-015369-72cjogxz 4716 3 patient patient NNP cord-015369-72cjogxz 4716 4 's 's POS cord-015369-72cjogxz 4716 5 satisfaction satisfaction NN cord-015369-72cjogxz 4716 6 was be VBD cord-015369-72cjogxz 4716 7 equal equal JJ cord-015369-72cjogxz 4716 8 in in IN cord-015369-72cjogxz 4716 9 both both DT cord-015369-72cjogxz 4716 10 groups group NNS cord-015369-72cjogxz 4716 11 . . . cord-015369-72cjogxz 4717 1 Review review NN cord-015369-72cjogxz 4717 2 : : : cord-015369-72cjogxz 4717 3 optimal optimal JJ cord-015369-72cjogxz 4717 4 biopsy biopsy NN cord-015369-72cjogxz 4717 5 protocol protocol NN cord-015369-72cjogxz 4717 6 in in IN cord-015369-72cjogxz 4717 7 GERD GERD NNP cord-015369-72cjogxz 4717 8 patients patient NNS cord-015369-72cjogxz 4717 9 Background Background NNP cord-015369-72cjogxz 4717 10 . . . cord-015369-72cjogxz 4718 1 Endoscopy endoscopy NN cord-015369-72cjogxz 4718 2 in in IN cord-015369-72cjogxz 4718 3 patients patient NNS cord-015369-72cjogxz 4718 4 with with IN cord-015369-72cjogxz 4718 5 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 4718 6 reflux reflux NN cord-015369-72cjogxz 4718 7 disease disease NN cord-015369-72cjogxz 4718 8 ( ( -LRB- cord-015369-72cjogxz 4718 9 GERD GERD NNP cord-015369-72cjogxz 4718 10 ) ) -RRB- cord-015369-72cjogxz 4718 11 aims aim VBZ cord-015369-72cjogxz 4718 12 to to TO cord-015369-72cjogxz 4718 13 assess assess VB cord-015369-72cjogxz 4718 14 presence presence NN cord-015369-72cjogxz 4718 15 or or CC cord-015369-72cjogxz 4718 16 absence absence NN cord-015369-72cjogxz 4718 17 of of IN cord-015369-72cjogxz 4718 18 reflux reflux NN cord-015369-72cjogxz 4718 19 and and CC cord-015369-72cjogxz 4718 20 cancer cancer NN cord-015369-72cjogxz 4718 21 risk risk NN cord-015369-72cjogxz 4718 22 . . . cord-015369-72cjogxz 4719 1 Remains remain VBZ cord-015369-72cjogxz 4719 2 to to TO cord-015369-72cjogxz 4719 3 be be VB cord-015369-72cjogxz 4719 4 questioned question VBN cord-015369-72cjogxz 4719 5 which which WDT cord-015369-72cjogxz 4719 6 biopsy biopsy NN cord-015369-72cjogxz 4719 7 protocol protocol NN cord-015369-72cjogxz 4719 8 adequately adequately RB cord-015369-72cjogxz 4719 9 meets meet VBZ cord-015369-72cjogxz 4719 10 these these DT cord-015369-72cjogxz 4719 11 requirements requirement NNS cord-015369-72cjogxz 4719 12 . . . cord-015369-72cjogxz 4720 1 Methods method NNS cord-015369-72cjogxz 4720 2 . . . cord-015369-72cjogxz 4721 1 Review review VB cord-015369-72cjogxz 4721 2 on on IN cord-015369-72cjogxz 4721 3 a a DT cord-015369-72cjogxz 4721 4 novel novel JJ cord-015369-72cjogxz 4721 5 histopathology histopathology NN cord-015369-72cjogxz 4721 6 based base VBN cord-015369-72cjogxz 4721 7 biopsy biopsy NN cord-015369-72cjogxz 4721 8 protocol protocol NN cord-015369-72cjogxz 4721 9 . . . cord-015369-72cjogxz 4722 1 Results result NNS cord-015369-72cjogxz 4722 2 . . . cord-015369-72cjogxz 4723 1 In in IN cord-015369-72cjogxz 4723 2 keeping keep VBG cord-015369-72cjogxz 4723 3 with with IN cord-015369-72cjogxz 4723 4 recent recent JJ cord-015369-72cjogxz 4723 5 endoscopy endoscopy NN cord-015369-72cjogxz 4723 6 and and CC cord-015369-72cjogxz 4723 7 biopsy biopsy NN cord-015369-72cjogxz 4723 8 studies study NNS cord-015369-72cjogxz 4723 9 coming come VBG cord-015369-72cjogxz 4723 10 from from IN cord-015369-72cjogxz 4723 11 others other NNS cord-015369-72cjogxz 4723 12 and and CC cord-015369-72cjogxz 4723 13 our -PRON- PRP$ cord-015369-72cjogxz 4723 14 group group NN cord-015369-72cjogxz 4723 15 , , , cord-015369-72cjogxz 4723 16 GERD GERD NNP cord-015369-72cjogxz 4723 17 causes cause VBZ cord-015369-72cjogxz 4723 18 a a DT cord-015369-72cjogxz 4723 19 specific specific JJ cord-015369-72cjogxz 4723 20 morphology morphology NN cord-015369-72cjogxz 4723 21 within within IN cord-015369-72cjogxz 4723 22 the the DT cord-015369-72cjogxz 4723 23 distal distal JJ cord-015369-72cjogxz 4723 24 esophagus esophagus NN cord-015369-72cjogxz 4723 25 : : : cord-015369-72cjogxz 4723 26 columnar columnar JJ cord-015369-72cjogxz 4723 27 lined line VBN cord-015369-72cjogxz 4723 28 esophagus esophagu NNS cord-015369-72cjogxz 4723 29 ( ( -LRB- cord-015369-72cjogxz 4723 30 CLE CLE NNP cord-015369-72cjogxz 4723 31 ) ) -RRB- cord-015369-72cjogxz 4723 32 . . . cord-015369-72cjogxz 4724 1 CLE CLE NNP cord-015369-72cjogxz 4724 2 is be VBZ cord-015369-72cjogxz 4724 3 interposed interpose VBN cord-015369-72cjogxz 4724 4 between between IN cord-015369-72cjogxz 4724 5 the the DT cord-015369-72cjogxz 4724 6 squamous squamous JJ cord-015369-72cjogxz 4724 7 lined line VBN cord-015369-72cjogxz 4724 8 esophagus esophagu NNS cord-015369-72cjogxz 4724 9 and and CC cord-015369-72cjogxz 4724 10 the the DT cord-015369-72cjogxz 4724 11 oxyntic oxyntic JJ cord-015369-72cjogxz 4724 12 mucosa mucosa NN cord-015369-72cjogxz 4724 13 of of IN cord-015369-72cjogxz 4724 14 the the DT cord-015369-72cjogxz 4724 15 proximal proximal JJ cord-015369-72cjogxz 4724 16 stomach stomach NN cord-015369-72cjogxz 4724 17 . . . cord-015369-72cjogxz 4725 1 The the DT cord-015369-72cjogxz 4725 2 assessment assessment NN cord-015369-72cjogxz 4725 3 of of IN cord-015369-72cjogxz 4725 4 CLE CLE NNP cord-015369-72cjogxz 4725 5 proofs proof NNS cord-015369-72cjogxz 4725 6 the the DT cord-015369-72cjogxz 4725 7 presence presence NN cord-015369-72cjogxz 4725 8 of of IN cord-015369-72cjogxz 4725 9 reflux reflux NN cord-015369-72cjogxz 4725 10 and and CC cord-015369-72cjogxz 4725 11 includes include VBZ cord-015369-72cjogxz 4725 12 oxyntocardiac oxyntocardiac NN cord-015369-72cjogxz 4725 13 , , , cord-015369-72cjogxz 4725 14 cardiac cardiac JJ cord-015369-72cjogxz 4725 15 mucosa mucosa NN cord-015369-72cjogxz 4725 16 AE AE NNP cord-015369-72cjogxz 4725 17 intestinal intestinal JJ cord-015369-72cjogxz 4725 18 metaplasia metaplasia NN cord-015369-72cjogxz 4725 19 ( ( -LRB- cord-015369-72cjogxz 4725 20 Barrett Barrett NNP cord-015369-72cjogxz 4725 21 's 's POS cord-015369-72cjogxz 4725 22 esophagus esophagus NN cord-015369-72cjogxz 4725 23 ) ) -RRB- cord-015369-72cjogxz 4725 24 . . . cord-015369-72cjogxz 4726 1 Over over IN cord-015369-72cjogxz 4726 2 a a DT cord-015369-72cjogxz 4726 3 sequence sequence NN cord-015369-72cjogxz 4726 4 involving involve VBG cord-015369-72cjogxz 4726 5 low low JJ cord-015369-72cjogxz 4726 6 - - HYPH cord-015369-72cjogxz 4726 7 and and CC cord-015369-72cjogxz 4726 8 high high JJ cord-015369-72cjogxz 4726 9 - - HYPH cord-015369-72cjogxz 4726 10 grade grade NN cord-015369-72cjogxz 4726 11 dysplasia dysplasia NN cord-015369-72cjogxz 4726 12 ( ( -LRB- cord-015369-72cjogxz 4726 13 intraepithelial intraepithelial JJ cord-015369-72cjogxz 4726 14 neoplasia neoplasia NN cord-015369-72cjogxz 4726 15 ) ) -RRB- cord-015369-72cjogxz 4727 1 intestinal intestinal JJ cord-015369-72cjogxz 4727 2 metaplasia metaplasia NNP cord-015369-72cjogxz 4727 3 may may MD cord-015369-72cjogxz 4727 4 progress progress VB cord-015369-72cjogxz 4727 5 towards towards IN cord-015369-72cjogxz 4727 6 esophageal esophageal JJ cord-015369-72cjogxz 4727 7 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 4727 8 ( ( -LRB- cord-015369-72cjogxz 4727 9 0.5 0.5 CD cord-015369-72cjogxz 4727 10 % % NN cord-015369-72cjogxz 4727 11 annual annual JJ cord-015369-72cjogxz 4727 12 risk risk NN cord-015369-72cjogxz 4727 13 ) ) -RRB- cord-015369-72cjogxz 4727 14 . . . cord-015369-72cjogxz 4728 1 Accordingly accordingly RB cord-015369-72cjogxz 4728 2 Barrett Barrett NNP cord-015369-72cjogxz 4728 3 's 's POS cord-015369-72cjogxz 4728 4 esophagus esophagus NN cord-015369-72cjogxz 4728 5 is be VBZ cord-015369-72cjogxz 4728 6 recognized recognize VBN cord-015369-72cjogxz 4728 7 as as IN cord-015369-72cjogxz 4728 8 having have VBG cord-015369-72cjogxz 4728 9 a a DT cord-015369-72cjogxz 4728 10 cancer cancer NN cord-015369-72cjogxz 4728 11 risk risk NN cord-015369-72cjogxz 4728 12 justifying justify VBG cord-015369-72cjogxz 4728 13 endoscopic endoscopic JJ cord-015369-72cjogxz 4728 14 surveillance surveillance NN cord-015369-72cjogxz 4728 15 . . . cord-015369-72cjogxz 4729 1 Based base VBN cord-015369-72cjogxz 4729 2 on on IN cord-015369-72cjogxz 4729 3 the the DT cord-015369-72cjogxz 4729 4 zonation zonation NN cord-015369-72cjogxz 4729 5 of of IN cord-015369-72cjogxz 4729 6 the the DT cord-015369-72cjogxz 4729 7 mucosal mucosal JJ cord-015369-72cjogxz 4729 8 types type NNS cord-015369-72cjogxz 4729 9 within within IN cord-015369-72cjogxz 4729 10 CLE CLE NNP cord-015369-72cjogxz 4729 11 ( ( -LRB- cord-015369-72cjogxz 4729 12 cardiac cardiac JJ cord-015369-72cjogxz 4729 13 mucosa mucosa NN cord-015369-72cjogxz 4729 14 AE AE NNP cord-015369-72cjogxz 4729 15 intestinal intestinal JJ cord-015369-72cjogxz 4729 16 metaplasia metaplasia NN cord-015369-72cjogxz 4729 17 and and CC cord-015369-72cjogxz 4729 18 oxyntocardiac oxyntocardiac NN cord-015369-72cjogxz 4729 19 mucosa mucosa RB cord-015369-72cjogxz 4729 20 favor favor VBP cord-015369-72cjogxz 4729 21 the the DT cord-015369-72cjogxz 4729 22 proximal proximal JJ cord-015369-72cjogxz 4729 23 and and CC cord-015369-72cjogxz 4729 24 distal distal JJ cord-015369-72cjogxz 4729 25 segment segment NN cord-015369-72cjogxz 4729 26 of of IN cord-015369-72cjogxz 4729 27 CLE CLE NNP cord-015369-72cjogxz 4729 28 , , , cord-015369-72cjogxz 4729 29 respectively respectively RB cord-015369-72cjogxz 4729 30 ) ) -RRB- cord-015369-72cjogxz 4729 31 , , , cord-015369-72cjogxz 4729 32 biopsies biopsy NNS cord-015369-72cjogxz 4729 33 obtained obtain VBN cord-015369-72cjogxz 4729 34 from from IN cord-015369-72cjogxz 4729 35 the the DT cord-015369-72cjogxz 4729 36 squa squa NNP cord-015369-72cjogxz 4729 37 - - HYPH cord-015369-72cjogxz 4729 38 mocolumnar mocolumnar NNP cord-015369-72cjogxz 4729 39 junction junction NNP cord-015369-72cjogxz 4729 40 have have VBP cord-015369-72cjogxz 4729 41 the the DT cord-015369-72cjogxz 4729 42 highest high JJS cord-015369-72cjogxz 4729 43 yield yield NN cord-015369-72cjogxz 4729 44 for for IN cord-015369-72cjogxz 4729 45 assessment assessment NN cord-015369-72cjogxz 4729 46 of of IN cord-015369-72cjogxz 4729 47 intestinal intestinal JJ cord-015369-72cjogxz 4729 48 metaplasia metaplasia NN cord-015369-72cjogxz 4729 49 ( ( -LRB- cord-015369-72cjogxz 4729 50 proofing proof VBG cord-015369-72cjogxz 4729 51 reflux reflux NN cord-015369-72cjogxz 4729 52 and and CC cord-015369-72cjogxz 4729 53 cancer cancer NN cord-015369-72cjogxz 4729 54 risk risk NN cord-015369-72cjogxz 4729 55 ) ) -RRB- cord-015369-72cjogxz 4729 56 . . . cord-015369-72cjogxz 4730 1 Thus thus RB cord-015369-72cjogxz 4730 2 the the DT cord-015369-72cjogxz 4730 3 biopsy biopsy NN cord-015369-72cjogxz 4730 4 protocol protocol NN cord-015369-72cjogxz 4730 5 should should MD cord-015369-72cjogxz 4730 6 include include VB cord-015369-72cjogxz 4730 7 at at RB cord-015369-72cjogxz 4730 8 least least RBS cord-015369-72cjogxz 4730 9 4 4 CD cord-015369-72cjogxz 4730 10 quadrant quadrant JJ cord-015369-72cjogxz 4730 11 biopsies biopsy NNS cord-015369-72cjogxz 4730 12 from from IN cord-015369-72cjogxz 4730 13 the the DT cord-015369-72cjogxz 4730 14 squamocolumnar squamocolumnar NNP cord-015369-72cjogxz 4730 15 junction junction NNP cord-015369-72cjogxz 4730 16 and and CC cord-015369-72cjogxz 4730 17 biopsies biopsy NNS cord-015369-72cjogxz 4730 18 obtained obtain VBN cord-015369-72cjogxz 4730 19 at at IN cord-015369-72cjogxz 4730 20 0.5 0.5 CD cord-015369-72cjogxz 4730 21 cm cm NNS cord-015369-72cjogxz 4730 22 increments increment NNS cord-015369-72cjogxz 4730 23 from from IN cord-015369-72cjogxz 4730 24 endoscopically endoscopically RB cord-015369-72cjogxz 4730 25 visible visible JJ cord-015369-72cjogxz 4730 26 tongues tongue NNS cord-015369-72cjogxz 4730 27 or or CC cord-015369-72cjogxz 4730 28 segments segment NNS cord-015369-72cjogxz 4730 29 of of IN cord-015369-72cjogxz 4730 30 CLE CLE NNP cord-015369-72cjogxz 4730 31 . . . cord-015369-72cjogxz 4731 1 Conclusions conclusion NNS cord-015369-72cjogxz 4731 2 . . . cord-015369-72cjogxz 4732 1 Four four CD cord-015369-72cjogxz 4732 2 quadrant quadrant JJ cord-015369-72cjogxz 4732 3 biopsies biopsy NNS cord-015369-72cjogxz 4732 4 obtained obtain VBN cord-015369-72cjogxz 4732 5 from from IN cord-015369-72cjogxz 4732 6 the the DT cord-015369-72cjogxz 4732 7 squamocolumnar squamocolumnar NNP cord-015369-72cjogxz 4732 8 junction junction NNP cord-015369-72cjogxz 4732 9 have have VBP cord-015369-72cjogxz 4732 10 the the DT cord-015369-72cjogxz 4732 11 highest high JJS cord-015369-72cjogxz 4732 12 yield yield NN cord-015369-72cjogxz 4732 13 for for IN cord-015369-72cjogxz 4732 14 the the DT cord-015369-72cjogxz 4732 15 assessment assessment NN cord-015369-72cjogxz 4732 16 of of IN cord-015369-72cjogxz 4732 17 reflux reflux NN cord-015369-72cjogxz 4732 18 and and CC cord-015369-72cjogxz 4732 19 cancer cancer NN cord-015369-72cjogxz 4732 20 risk risk NN cord-015369-72cjogxz 4732 21 and and CC cord-015369-72cjogxz 4732 22 should should MD cord-015369-72cjogxz 4732 23 be be VB cord-015369-72cjogxz 4732 24 included include VBN cord-015369-72cjogxz 4732 25 into into IN cord-015369-72cjogxz 4732 26 the the DT cord-015369-72cjogxz 4732 27 routine routine JJ cord-015369-72cjogxz 4732 28 biopsy biopsy NN cord-015369-72cjogxz 4732 29 protocol protocol NN cord-015369-72cjogxz 4732 30 in in IN cord-015369-72cjogxz 4732 31 GERD GERD NNP cord-015369-72cjogxz 4732 32 patients patient NNS cord-015369-72cjogxz 4732 33 . . . cord-015369-72cjogxz 4733 1 Variceal Variceal NNP cord-015369-72cjogxz 4733 2 bleeding bleed VBG cord-015369-72cjogxz 4733 3 . . . cord-015369-72cjogxz 4734 1 A a DT cord-015369-72cjogxz 4734 2 Danish danish JJ cord-015369-72cjogxz 4734 3 expirience expirience NN cord-015369-72cjogxz 4734 4 with with IN cord-015369-72cjogxz 4734 5 the the DT cord-015369-72cjogxz 4734 6 Ella Ella NNP cord-015369-72cjogxz 4734 7 - - HYPH cord-015369-72cjogxz 4734 8 Danis Danis NNP cord-015369-72cjogxz 4734 9 stent stent NN cord-015369-72cjogxz 4734 10 Gastroenheden Gastroenheden NNP cord-015369-72cjogxz 4734 11 , , , cord-015369-72cjogxz 4734 12 Hvidovre Hvidovre NNP cord-015369-72cjogxz 4734 13 Hospital Hospital NNP cord-015369-72cjogxz 4734 14 , , , cord-015369-72cjogxz 4734 15 Hvidovre Hvidovre NNP cord-015369-72cjogxz 4734 16 , , , cord-015369-72cjogxz 4734 17 Denmark Denmark NNP cord-015369-72cjogxz 4734 18 Background Background NNP cord-015369-72cjogxz 4734 19 . . . cord-015369-72cjogxz 4735 1 Despite despite IN cord-015369-72cjogxz 4735 2 effective effective JJ cord-015369-72cjogxz 4735 3 treatment treatment NN cord-015369-72cjogxz 4735 4 modalities modality NNS cord-015369-72cjogxz 4735 5 such such JJ cord-015369-72cjogxz 4735 6 as as IN cord-015369-72cjogxz 4735 7 vasoactive vasoactive JJ cord-015369-72cjogxz 4735 8 drugs drug NNS cord-015369-72cjogxz 4735 9 , , , cord-015369-72cjogxz 4735 10 banding band VBG cord-015369-72cjogxz 4735 11 therapy therapy NN cord-015369-72cjogxz 4735 12 and and CC cord-015369-72cjogxz 4735 13 sclerotherapy sclerotherapy NNP cord-015369-72cjogxz 4735 14 , , , cord-015369-72cjogxz 4735 15 a a DT cord-015369-72cjogxz 4735 16 fraction fraction NN cord-015369-72cjogxz 4735 17 of of IN cord-015369-72cjogxz 4735 18 the the DT cord-015369-72cjogxz 4735 19 esophageal esophageal JJ cord-015369-72cjogxz 4735 20 varices varix NNS cord-015369-72cjogxz 4735 21 continue continue VBP cord-015369-72cjogxz 4735 22 to to TO cord-015369-72cjogxz 4735 23 bleed bleed VB cord-015369-72cjogxz 4735 24 . . . cord-015369-72cjogxz 4736 1 Until until IN cord-015369-72cjogxz 4736 2 recently recently RB cord-015369-72cjogxz 4736 3 , , , cord-015369-72cjogxz 4736 4 the the DT cord-015369-72cjogxz 4736 5 Sengstaken Sengstaken NNP cord-015369-72cjogxz 4736 6 - - HYPH cord-015369-72cjogxz 4736 7 Blakemore Blakemore NNP cord-015369-72cjogxz 4736 8 tube tube NN cord-015369-72cjogxz 4736 9 has have VBZ cord-015369-72cjogxz 4736 10 been be VBN cord-015369-72cjogxz 4736 11 the the DT cord-015369-72cjogxz 4736 12 method method NN cord-015369-72cjogxz 4736 13 of of IN cord-015369-72cjogxz 4736 14 choice choice NN cord-015369-72cjogxz 4736 15 for for IN cord-015369-72cjogxz 4736 16 those those DT cord-015369-72cjogxz 4736 17 patients patient NNS cord-015369-72cjogxz 4736 18 . . . cord-015369-72cjogxz 4737 1 There there EX cord-015369-72cjogxz 4737 2 are be VBP cord-015369-72cjogxz 4737 3 , , , cord-015369-72cjogxz 4737 4 however however RB cord-015369-72cjogxz 4737 5 , , , cord-015369-72cjogxz 4737 6 numerous numerous JJ cord-015369-72cjogxz 4737 7 disadvantages disadvantage NNS cord-015369-72cjogxz 4737 8 with with IN cord-015369-72cjogxz 4737 9 the the DT cord-015369-72cjogxz 4737 10 tube tube NN cord-015369-72cjogxz 4737 11 . . . cord-015369-72cjogxz 4738 1 Methods method NNS cord-015369-72cjogxz 4738 2 . . . cord-015369-72cjogxz 4739 1 The the DT cord-015369-72cjogxz 4739 2 first first JJ cord-015369-72cjogxz 4739 3 seven seven CD cord-015369-72cjogxz 4739 4 patients patient NNS cord-015369-72cjogxz 4739 5 treated treat VBN cord-015369-72cjogxz 4739 6 with with IN cord-015369-72cjogxz 4739 7 the the DT cord-015369-72cjogxz 4739 8 Ella Ella NNP cord-015369-72cjogxz 4739 9 - - HYPH cord-015369-72cjogxz 4739 10 Danis Danis NNP cord-015369-72cjogxz 4739 11 stent stent NN cord-015369-72cjogxz 4739 12 ( ( -LRB- cord-015369-72cjogxz 4739 13 E e NN cord-015369-72cjogxz 4739 14 - - NN cord-015369-72cjogxz 4739 15 DS DS NNP cord-015369-72cjogxz 4739 16 ) ) -RRB- cord-015369-72cjogxz 4739 17 in in IN cord-015369-72cjogxz 4739 18 our -PRON- PRP$ cord-015369-72cjogxz 4739 19 institution institution NN cord-015369-72cjogxz 4739 20 are be VBP cord-015369-72cjogxz 4739 21 presented present VBN cord-015369-72cjogxz 4739 22 . . . cord-015369-72cjogxz 4740 1 In in IN cord-015369-72cjogxz 4740 2 all all DT cord-015369-72cjogxz 4740 3 patients patient NNS cord-015369-72cjogxz 4740 4 other other JJ cord-015369-72cjogxz 4740 5 methods method NNS cord-015369-72cjogxz 4740 6 to to TO cord-015369-72cjogxz 4740 7 achieve achieve VB cord-015369-72cjogxz 4740 8 bleeding bleed VBG cord-015369-72cjogxz 4740 9 control control NN cord-015369-72cjogxz 4740 10 had have VBD cord-015369-72cjogxz 4740 11 failed fail VBN cord-015369-72cjogxz 4740 12 . . . cord-015369-72cjogxz 4741 1 All all DT cord-015369-72cjogxz 4741 2 patients patient NNS cord-015369-72cjogxz 4741 3 had have VBD cord-015369-72cjogxz 4741 4 alcoholic alcoholic JJ cord-015369-72cjogxz 4741 5 liver liver NN cord-015369-72cjogxz 4741 6 cirrhosis cirrhosis NN cord-015369-72cjogxz 4741 7 . . . cord-015369-72cjogxz 4742 1 Results result NNS cord-015369-72cjogxz 4742 2 . . . cord-015369-72cjogxz 4743 1 In in IN cord-015369-72cjogxz 4743 2 all all DT cord-015369-72cjogxz 4743 3 patients patient NNS cord-015369-72cjogxz 4743 4 the the DT cord-015369-72cjogxz 4743 5 placement placement NN cord-015369-72cjogxz 4743 6 of of IN cord-015369-72cjogxz 4743 7 the the DT cord-015369-72cjogxz 4743 8 E E NNP cord-015369-72cjogxz 4743 9 - - NN cord-015369-72cjogxz 4743 10 DS DS NNP cord-015369-72cjogxz 4743 11 was be VBD cord-015369-72cjogxz 4743 12 uncomplicated uncomplicated JJ cord-015369-72cjogxz 4743 13 and and CC cord-015369-72cjogxz 4743 14 variceal variceal JJ cord-015369-72cjogxz 4743 15 bleeding bleeding NN cord-015369-72cjogxz 4743 16 stopped stop VBD cord-015369-72cjogxz 4743 17 immediately immediately RB cord-015369-72cjogxz 4743 18 . . . cord-015369-72cjogxz 4744 1 The the DT cord-015369-72cjogxz 4744 2 E e NN cord-015369-72cjogxz 4744 3 - - NN cord-015369-72cjogxz 4744 4 DS DS NNP cord-015369-72cjogxz 4744 5 was be VBD cord-015369-72cjogxz 4744 6 in in IN cord-015369-72cjogxz 4744 7 place place NN cord-015369-72cjogxz 4744 8 from from IN cord-015369-72cjogxz 4744 9 5 5 CD cord-015369-72cjogxz 4744 10 to to TO cord-015369-72cjogxz 4744 11 14 14 CD cord-015369-72cjogxz 4744 12 days day NNS cord-015369-72cjogxz 4744 13 . . . cord-015369-72cjogxz 4745 1 The the DT cord-015369-72cjogxz 4745 2 removal removal NN cord-015369-72cjogxz 4745 3 of of IN cord-015369-72cjogxz 4745 4 the the DT cord-015369-72cjogxz 4745 5 stent stent NN cord-015369-72cjogxz 4745 6 was be VBD cord-015369-72cjogxz 4745 7 done do VBN cord-015369-72cjogxz 4745 8 under under IN cord-015369-72cjogxz 4745 9 endoscopic endoscopic JJ cord-015369-72cjogxz 4745 10 control control NN cord-015369-72cjogxz 4745 11 by by IN cord-015369-72cjogxz 4745 12 means mean NNS cord-015369-72cjogxz 4745 13 of of IN cord-015369-72cjogxz 4745 14 an an DT cord-015369-72cjogxz 4745 15 overtube overtube NN cord-015369-72cjogxz 4745 16 and and CC cord-015369-72cjogxz 4745 17 a a DT cord-015369-72cjogxz 4745 18 biopsy biopsy NN cord-015369-72cjogxz 4745 19 -or -or HYPH cord-015369-72cjogxz 4745 20 rotating rotate VBG cord-015369-72cjogxz 4745 21 forceps forceps NNS cord-015369-72cjogxz 4745 22 . . . cord-015369-72cjogxz 4746 1 No no DT cord-015369-72cjogxz 4746 2 complications complication NNS cord-015369-72cjogxz 4746 3 were be VBD cord-015369-72cjogxz 4746 4 encountered encounter VBN cord-015369-72cjogxz 4746 5 . . . cord-015369-72cjogxz 4747 1 Conclusions conclusion NNS cord-015369-72cjogxz 4747 2 . . . cord-015369-72cjogxz 4748 1 The the DT cord-015369-72cjogxz 4748 2 E e NN cord-015369-72cjogxz 4748 3 - - NN cord-015369-72cjogxz 4748 4 DS DS NNP cord-015369-72cjogxz 4748 5 is be VBZ cord-015369-72cjogxz 4748 6 excellent excellent JJ cord-015369-72cjogxz 4748 7 as as IN cord-015369-72cjogxz 4748 8 rescue rescue NN cord-015369-72cjogxz 4748 9 therapy therapy NN cord-015369-72cjogxz 4748 10 in in IN cord-015369-72cjogxz 4748 11 patients patient NNS cord-015369-72cjogxz 4748 12 with with IN cord-015369-72cjogxz 4748 13 bleeding bleed VBG cord-015369-72cjogxz 4748 14 esophageal esophageal JJ cord-015369-72cjogxz 4748 15 varices varix NNS cord-015369-72cjogxz 4748 16 in in IN cord-015369-72cjogxz 4748 17 cases case NNS cord-015369-72cjogxz 4748 18 where where WRB cord-015369-72cjogxz 4748 19 other other JJ cord-015369-72cjogxz 4748 20 treatments treatment NNS cord-015369-72cjogxz 4748 21 have have VBP cord-015369-72cjogxz 4748 22 failed fail VBN cord-015369-72cjogxz 4748 23 . . . cord-015369-72cjogxz 4749 1 Internet internet NN cord-015369-72cjogxz 4749 2 platform platform NN cord-015369-72cjogxz 4749 3 for for IN cord-015369-72cjogxz 4749 4 novel novel JJ cord-015369-72cjogxz 4749 5 GERD GERD NNP cord-015369-72cjogxz 4749 6 management management NN cord-015369-72cjogxz 4749 7 : : : cord-015369-72cjogxz 4749 8 www.iGERD.com www.igerd.com ADD cord-015369-72cjogxz 4749 9 Background Background NNP cord-015369-72cjogxz 4749 10 . . . cord-015369-72cjogxz 4750 1 Currently currently RB cord-015369-72cjogxz 4750 2 a a DT cord-015369-72cjogxz 4750 3 mixture mixture NN cord-015369-72cjogxz 4750 4 of of IN cord-015369-72cjogxz 4750 5 symptoms symptom NNS cord-015369-72cjogxz 4750 6 , , , cord-015369-72cjogxz 4750 7 data datum NNS cord-015369-72cjogxz 4750 8 obtained obtain VBN cord-015369-72cjogxz 4750 9 from from IN cord-015369-72cjogxz 4750 10 endoscopy endoscopy NN cord-015369-72cjogxz 4750 11 , , , cord-015369-72cjogxz 4750 12 histopathology histopathology NN cord-015369-72cjogxz 4750 13 , , , cord-015369-72cjogxz 4750 14 function function NN cord-015369-72cjogxz 4750 15 tests test NNS cord-015369-72cjogxz 4750 16 and and CC cord-015369-72cjogxz 4750 17 radiology radiology NN cord-015369-72cjogxz 4750 18 define define VBP cord-015369-72cjogxz 4750 19 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 4750 20 reflux reflux NN cord-015369-72cjogxz 4750 21 disease disease NN cord-015369-72cjogxz 4750 22 ( ( -LRB- cord-015369-72cjogxz 4750 23 GERD GERD NNP cord-015369-72cjogxz 4750 24 ) ) -RRB- cord-015369-72cjogxz 4750 25 . . . cord-015369-72cjogxz 4751 1 Recently recently RB cord-015369-72cjogxz 4751 2 an an DT cord-015369-72cjogxz 4751 3 histopathology histopathology NN cord-015369-72cjogxz 4751 4 based base VBN cord-015369-72cjogxz 4751 5 concept concept NN cord-015369-72cjogxz 4751 6 for for IN cord-015369-72cjogxz 4751 7 GERD GERD NNP cord-015369-72cjogxz 4751 8 diagnosis diagnosis NN cord-015369-72cjogxz 4751 9 and and CC cord-015369-72cjogxz 4751 10 management management NN cord-015369-72cjogxz 4751 11 has have VBZ cord-015369-72cjogxz 4751 12 been be VBN cord-015369-72cjogxz 4751 13 introduced introduce VBN cord-015369-72cjogxz 4751 14 ( ( -LRB- cord-015369-72cjogxz 4751 15 Paull Paull NNP cord-015369-72cjogxz 4751 16 - - HYPH cord-015369-72cjogxz 4751 17 Chandrasoma Chandrasoma NNP cord-015369-72cjogxz 4751 18 Classification Classification NNP cord-015369-72cjogxz 4751 19 ) ) -RRB- cord-015369-72cjogxz 4751 20 . . . cord-015369-72cjogxz 4752 1 We -PRON- PRP cord-015369-72cjogxz 4752 2 aimed aim VBD cord-015369-72cjogxz 4752 3 to to TO cord-015369-72cjogxz 4752 4 create create VB cord-015369-72cjogxz 4752 5 a a DT cord-015369-72cjogxz 4752 6 platform platform NN cord-015369-72cjogxz 4752 7 for for IN cord-015369-72cjogxz 4752 8 these these DT cord-015369-72cjogxz 4752 9 novel novel JJ cord-015369-72cjogxz 4752 10 developments development NNS cord-015369-72cjogxz 4752 11 . . . cord-015369-72cjogxz 4753 1 Methods method NNS cord-015369-72cjogxz 4753 2 . . . cord-015369-72cjogxz 4754 1 Design design NN cord-015369-72cjogxz 4754 2 of of IN cord-015369-72cjogxz 4754 3 an an DT cord-015369-72cjogxz 4754 4 interactive interactive JJ cord-015369-72cjogxz 4754 5 , , , cord-015369-72cjogxz 4754 6 easy easy JJ cord-015369-72cjogxz 4754 7 to to TO cord-015369-72cjogxz 4754 8 use use VB cord-015369-72cjogxz 4754 9 internet internet NN cord-015369-72cjogxz 4754 10 - - HYPH cord-015369-72cjogxz 4754 11 based base VBN cord-015369-72cjogxz 4754 12 platform platform NN cord-015369-72cjogxz 4754 13 on on IN cord-015369-72cjogxz 4754 14 GERD GERD NNP cord-015369-72cjogxz 4754 15 management management NN cord-015369-72cjogxz 4754 16 for for IN cord-015369-72cjogxz 4754 17 physicians physician NNS cord-015369-72cjogxz 4754 18 and and CC cord-015369-72cjogxz 4754 19 patients patient NNS cord-015369-72cjogxz 4754 20 . . . cord-015369-72cjogxz 4755 1 Results result NNS cord-015369-72cjogxz 4755 2 . . . cord-015369-72cjogxz 4756 1 iGERD iGERD NNP cord-015369-72cjogxz 4756 2 for for IN cord-015369-72cjogxz 4756 3 physicians physician NNS cord-015369-72cjogxz 4756 4 compares compare VBZ cord-015369-72cjogxz 4756 5 the the DT cord-015369-72cjogxz 4756 6 currently currently RB cord-015369-72cjogxz 4756 7 used use VBN cord-015369-72cjogxz 4756 8 concept concept NN cord-015369-72cjogxz 4756 9 with with IN cord-015369-72cjogxz 4756 10 the the DT cord-015369-72cjogxz 4756 11 novel novel NN cord-015369-72cjogxz 4756 12 , , , cord-015369-72cjogxz 4756 13 histopathology histopathology NN cord-015369-72cjogxz 4756 14 based base VBN cord-015369-72cjogxz 4756 15 concept concept NN cord-015369-72cjogxz 4756 16 for for IN cord-015369-72cjogxz 4756 17 GERD GERD NNP cord-015369-72cjogxz 4756 18 diagnosis diagnosis NN cord-015369-72cjogxz 4756 19 and and CC cord-015369-72cjogxz 4756 20 management management NN cord-015369-72cjogxz 4756 21 . . . cord-015369-72cjogxz 4757 1 The the DT cord-015369-72cjogxz 4757 2 information information NN cord-015369-72cjogxz 4757 3 is be VBZ cord-015369-72cjogxz 4757 4 presented present VBN cord-015369-72cjogxz 4757 5 using use VBG cord-015369-72cjogxz 4757 6 text text NN cord-015369-72cjogxz 4757 7 , , , cord-015369-72cjogxz 4757 8 images image NNS cord-015369-72cjogxz 4757 9 , , , cord-015369-72cjogxz 4757 10 slide slide NN cord-015369-72cjogxz 4757 11 shows show NNS cord-015369-72cjogxz 4757 12 and and CC cord-015369-72cjogxz 4757 13 video video NN cord-015369-72cjogxz 4757 14 pod pod NN cord-015369-72cjogxz 4757 15 casts cast VBZ cord-015369-72cjogxz 4757 16 ( ( -LRB- cord-015369-72cjogxz 4757 17 topics topic NNS cord-015369-72cjogxz 4757 18 : : : cord-015369-72cjogxz 4757 19 endoscopy endoscopy NN cord-015369-72cjogxz 4757 20 videos video NNS cord-015369-72cjogxz 4757 21 , , , cord-015369-72cjogxz 4757 22 biopsy biopsy NN cord-015369-72cjogxz 4757 23 protocol protocol NN cord-015369-72cjogxz 4757 24 , , , cord-015369-72cjogxz 4757 25 histopathology histopathology NN cord-015369-72cjogxz 4757 26 , , , cord-015369-72cjogxz 4757 27 manometry manometry NNP cord-015369-72cjogxz 4757 28 , , , cord-015369-72cjogxz 4758 1 pH pH NNP cord-015369-72cjogxz 4758 2 monitoring monitoring NN cord-015369-72cjogxz 4758 3 , , , cord-015369-72cjogxz 4758 4 impedance impedance NN cord-015369-72cjogxz 4758 5 technology technology NN cord-015369-72cjogxz 4758 6 , , , cord-015369-72cjogxz 4758 7 treatment treatment NN cord-015369-72cjogxz 4758 8 algorithms algorithm NNS cord-015369-72cjogxz 4758 9 ) ) -RRB- cord-015369-72cjogxz 4758 10 . . . cord-015369-72cjogxz 4759 1 iGERD iGERD NNP cord-015369-72cjogxz 4759 2 news news NNP cord-015369-72cjogxz 4759 3 summarizes summarize VBZ cord-015369-72cjogxz 4759 4 recently recently RB cord-015369-72cjogxz 4759 5 published publish VBD cord-015369-72cjogxz 4759 6 papers paper NNS cord-015369-72cjogxz 4759 7 on on IN cord-015369-72cjogxz 4759 8 GERD GERD NNP cord-015369-72cjogxz 4759 9 . . . cord-015369-72cjogxz 4760 1 In in IN cord-015369-72cjogxz 4760 2 addition addition NN cord-015369-72cjogxz 4760 3 , , , cord-015369-72cjogxz 4760 4 iGERD iGERD NNP cord-015369-72cjogxz 4760 5 provides provide VBZ cord-015369-72cjogxz 4760 6 patient patient JJ cord-015369-72cjogxz 4760 7 informations information NNS cord-015369-72cjogxz 4760 8 . . . cord-015369-72cjogxz 4761 1 The the DT cord-015369-72cjogxz 4761 2 content content NN cord-015369-72cjogxz 4761 3 is be VBZ cord-015369-72cjogxz 4761 4 monthly monthly RB cord-015369-72cjogxz 4761 5 updated update VBN cord-015369-72cjogxz 4761 6 by by IN cord-015369-72cjogxz 4761 7 members member NNS cord-015369-72cjogxz 4761 8 of of IN cord-015369-72cjogxz 4761 9 the the DT cord-015369-72cjogxz 4761 10 scientific scientific JJ cord-015369-72cjogxz 4761 11 board board NN cord-015369-72cjogxz 4761 12 . . . cord-015369-72cjogxz 4762 1 iGERD iGERD NNP cord-015369-72cjogxz 4762 2 can can MD cord-015369-72cjogxz 4762 3 be be VB cord-015369-72cjogxz 4762 4 followed follow VBN cord-015369-72cjogxz 4762 5 within within IN cord-015369-72cjogxz 4762 6 the the DT cord-015369-72cjogxz 4762 7 internet internet NN cord-015369-72cjogxz 4762 8 ( ( -LRB- cord-015369-72cjogxz 4762 9 www.iGERD.com www.igerd.com ADD cord-015369-72cjogxz 4762 10 ) ) -RRB- cord-015369-72cjogxz 4762 11 or or CC cord-015369-72cjogxz 4762 12 the the DT cord-015369-72cjogxz 4762 13 content content NN cord-015369-72cjogxz 4762 14 can can MD cord-015369-72cjogxz 4762 15 be be VB cord-015369-72cjogxz 4762 16 downloaded download VBN cord-015369-72cjogxz 4762 17 on on IN cord-015369-72cjogxz 4762 18 a a DT cord-015369-72cjogxz 4762 19 personal personal JJ cord-015369-72cjogxz 4762 20 computer computer NN cord-015369-72cjogxz 4762 21 ( ( -LRB- cord-015369-72cjogxz 4762 22 PC pc NN cord-015369-72cjogxz 4762 23 , , , cord-015369-72cjogxz 4762 24 MAC MAC NNP cord-015369-72cjogxz 4762 25 ) ) -RRB- cord-015369-72cjogxz 4762 26 and and CC cord-015369-72cjogxz 4762 27 transferred transfer VBN cord-015369-72cjogxz 4762 28 to to IN cord-015369-72cjogxz 4762 29 iPOD iPOD NNP cord-015369-72cjogxz 4762 30 and and CC cord-015369-72cjogxz 4762 31 iPhone iPhone NNP cord-015369-72cjogxz 4762 32 , , , cord-015369-72cjogxz 4762 33 using use VBG cord-015369-72cjogxz 4762 34 iTunes iTunes NNP cord-015369-72cjogxz 4762 35 . . . cord-015369-72cjogxz 4763 1 With with IN cord-015369-72cjogxz 4763 2 these these DT cord-015369-72cjogxz 4763 3 tools tool NNS cord-015369-72cjogxz 4763 4 videos video NNS cord-015369-72cjogxz 4763 5 and and CC cord-015369-72cjogxz 4763 6 slide slide NN cord-015369-72cjogxz 4763 7 shows show NNS cord-015369-72cjogxz 4763 8 can can MD cord-015369-72cjogxz 4763 9 be be VB cord-015369-72cjogxz 4763 10 followed follow VBN cord-015369-72cjogxz 4763 11 using use VBG cord-015369-72cjogxz 4763 12 the the DT cord-015369-72cjogxz 4763 13 interactive interactive JJ cord-015369-72cjogxz 4763 14 stop stop NN cord-015369-72cjogxz 4763 15 and and CC cord-015369-72cjogxz 4763 16 go go VB cord-015369-72cjogxz 4763 17 function function VB cord-015369-72cjogxz 4763 18 . . . cord-015369-72cjogxz 4764 1 Thus thus RB cord-015369-72cjogxz 4764 2 iGERD iGERD NNP cord-015369-72cjogxz 4764 3 meets meet VBZ cord-015369-72cjogxz 4764 4 the the DT cord-015369-72cjogxz 4764 5 requirements requirement NNS cord-015369-72cjogxz 4764 6 of of IN cord-015369-72cjogxz 4764 7 the the DT cord-015369-72cjogxz 4764 8 present present JJ cord-015369-72cjogxz 4764 9 time time NN cord-015369-72cjogxz 4764 10 : : : cord-015369-72cjogxz 4764 11 actuality actuality NN cord-015369-72cjogxz 4764 12 , , , cord-015369-72cjogxz 4764 13 mobility mobility NN cord-015369-72cjogxz 4764 14 and and CC cord-015369-72cjogxz 4764 15 flexibility flexibility NN cord-015369-72cjogxz 4764 16 . . . cord-015369-72cjogxz 4765 1 Conclusions conclusion NNS cord-015369-72cjogxz 4765 2 . . . cord-015369-72cjogxz 4766 1 iGERD iGERD NNP cord-015369-72cjogxz 4766 2 represents represent VBZ cord-015369-72cjogxz 4766 3 an an DT cord-015369-72cjogxz 4766 4 interactive interactive JJ cord-015369-72cjogxz 4766 5 internet internet NN cord-015369-72cjogxz 4766 6 - - HYPH cord-015369-72cjogxz 4766 7 based base VBN cord-015369-72cjogxz 4766 8 information information NN cord-015369-72cjogxz 4766 9 and and CC cord-015369-72cjogxz 4766 10 e e LS cord-015369-72cjogxz 4766 11 - - JJ cord-015369-72cjogxz 4766 12 learning learn VBG cord-015369-72cjogxz 4766 13 platform platform NN cord-015369-72cjogxz 4766 14 for for IN cord-015369-72cjogxz 4766 15 GERD GERD NNP cord-015369-72cjogxz 4766 16 management management NN cord-015369-72cjogxz 4766 17 designed design VBN cord-015369-72cjogxz 4766 18 for for IN cord-015369-72cjogxz 4766 19 physicians physician NNS cord-015369-72cjogxz 4766 20 and and CC cord-015369-72cjogxz 4766 21 patients patient NNS cord-015369-72cjogxz 4766 22 . . . cord-015369-72cjogxz 4767 1 Temporary temporary JJ cord-015369-72cjogxz 4767 2 placement placement NN cord-015369-72cjogxz 4767 3 of of IN cord-015369-72cjogxz 4767 4 self self NN cord-015369-72cjogxz 4767 5 - - HYPH cord-015369-72cjogxz 4767 6 expanding expand VBG cord-015369-72cjogxz 4767 7 oesophageal oesophageal JJ cord-015369-72cjogxz 4767 8 stents stent NNS cord-015369-72cjogxz 4767 9 as as IN cord-015369-72cjogxz 4767 10 bridging bridge VBG cord-015369-72cjogxz 4767 11 for for IN cord-015369-72cjogxz 4767 12 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 4767 13 therapy therapy NN cord-015369-72cjogxz 4767 14 Background Background NNP cord-015369-72cjogxz 4767 15 . . . cord-015369-72cjogxz 4768 1 Placement placement NN cord-015369-72cjogxz 4768 2 of of IN cord-015369-72cjogxz 4768 3 self self NN cord-015369-72cjogxz 4768 4 - - HYPH cord-015369-72cjogxz 4768 5 expanding expand VBG cord-015369-72cjogxz 4768 6 stents stent NNS cord-015369-72cjogxz 4768 7 is be VBZ cord-015369-72cjogxz 4768 8 the the DT cord-015369-72cjogxz 4768 9 most most RBS cord-015369-72cjogxz 4768 10 commonly commonly RB cord-015369-72cjogxz 4768 11 applied apply VBN cord-015369-72cjogxz 4768 12 palliation palliation NN cord-015369-72cjogxz 4768 13 for for IN cord-015369-72cjogxz 4768 14 dysphagia dysphagia NN cord-015369-72cjogxz 4768 15 in in IN cord-015369-72cjogxz 4768 16 non non JJ cord-015369-72cjogxz 4768 17 - - JJ cord-015369-72cjogxz 4768 18 resectable resectable JJ cord-015369-72cjogxz 4768 19 esophageal esophageal NN cord-015369-72cjogxz 4768 20 or or CC cord-015369-72cjogxz 4768 21 proximal proximal JJ cord-015369-72cjogxz 4768 22 gastric gastric JJ cord-015369-72cjogxz 4768 23 cancer cancer NN cord-015369-72cjogxz 4768 24 ( ( -LRB- cord-015369-72cjogxz 4768 25 AEG AEG NNP cord-015369-72cjogxz 4768 26 II II NNP cord-015369-72cjogxz 4768 27 , , , cord-015369-72cjogxz 4768 28 AEG AEG NNP cord-015369-72cjogxz 4768 29 III III NNP cord-015369-72cjogxz 4768 30 ) ) -RRB- cord-015369-72cjogxz 4768 31 . . . cord-015369-72cjogxz 4769 1 The the DT cord-015369-72cjogxz 4769 2 aim aim NN cord-015369-72cjogxz 4769 3 of of IN cord-015369-72cjogxz 4769 4 this this DT cord-015369-72cjogxz 4769 5 analysis analysis NN cord-015369-72cjogxz 4769 6 was be VBD cord-015369-72cjogxz 4769 7 to to TO cord-015369-72cjogxz 4769 8 assess assess VB cord-015369-72cjogxz 4769 9 the the DT cord-015369-72cjogxz 4769 10 efficacy efficacy NN cord-015369-72cjogxz 4769 11 of of IN cord-015369-72cjogxz 4769 12 temporary temporary JJ cord-015369-72cjogxz 4769 13 stent stent NN cord-015369-72cjogxz 4769 14 placement placement NN cord-015369-72cjogxz 4769 15 for for IN cord-015369-72cjogxz 4769 16 dysphagia dysphagia NN cord-015369-72cjogxz 4769 17 relief relief NN cord-015369-72cjogxz 4769 18 enabling enable VBG cord-015369-72cjogxz 4769 19 neo neo NNP cord-015369-72cjogxz 4769 20 - - HYPH cord-015369-72cjogxz 4769 21 adjuvant adjuvant JJ cord-015369-72cjogxz 4769 22 treatment treatment NN cord-015369-72cjogxz 4769 23 strategies strategy NNS cord-015369-72cjogxz 4769 24 for for IN cord-015369-72cjogxz 4769 25 locally locally RB cord-015369-72cjogxz 4769 26 advanced advanced JJ cord-015369-72cjogxz 4769 27 disease disease NN cord-015369-72cjogxz 4769 28 . . . cord-015369-72cjogxz 4770 1 Methods method NNS cord-015369-72cjogxz 4770 2 . . . cord-015369-72cjogxz 4771 1 Thirty thirty CD cord-015369-72cjogxz 4771 2 - - HYPH cord-015369-72cjogxz 4771 3 eight eight CD cord-015369-72cjogxz 4771 4 patients patient NNS cord-015369-72cjogxz 4771 5 scheduled schedule VBN cord-015369-72cjogxz 4771 6 for for IN cord-015369-72cjogxz 4771 7 neo neo NNP cord-015369-72cjogxz 4771 8 - - HYPH cord-015369-72cjogxz 4771 9 adjuvant adjuvant JJ cord-015369-72cjogxz 4771 10 chemo(radio)therapy chemo(radio)therapy NN cord-015369-72cjogxz 4771 11 for for IN cord-015369-72cjogxz 4771 12 locally locally RB cord-015369-72cjogxz 4771 13 advanced advanced JJ cord-015369-72cjogxz 4771 14 esophageal esophageal JJ cord-015369-72cjogxz 4771 15 cancer cancer NN cord-015369-72cjogxz 4771 16 ( ( -LRB- cord-015369-72cjogxz 4771 17 n n NNP cord-015369-72cjogxz 4771 18 29 29 CD cord-015369-72cjogxz 4771 19 ) ) -RRB- cord-015369-72cjogxz 4771 20 , , , cord-015369-72cjogxz 4771 21 cardia cardia NNP cord-015369-72cjogxz 4771 22 cancer cancer NN cord-015369-72cjogxz 4771 23 ( ( -LRB- cord-015369-72cjogxz 4771 24 AEG AEG NNP cord-015369-72cjogxz 4771 25 II II NNP cord-015369-72cjogxz 4771 26 ; ; : cord-015369-72cjogxz 4771 27 n n NNP cord-015369-72cjogxz 4771 28 ¼ ¼ NNP cord-015369-72cjogxz 4771 29 8) 8) NNP cord-015369-72cjogxz 4771 30 or or CC cord-015369-72cjogxz 4771 31 subcardial subcardial JJ cord-015369-72cjogxz 4771 32 gastric gastric JJ cord-015369-72cjogxz 4771 33 cancer cancer NN cord-015369-72cjogxz 4771 34 ( ( -LRB- cord-015369-72cjogxz 4771 35 AEG AEG NNP cord-015369-72cjogxz 4771 36 III III NNP cord-015369-72cjogxz 4771 37 ; ; : cord-015369-72cjogxz 4771 38 n n NN cord-015369-72cjogxz 4771 39 ¼ ¼ NNP cord-015369-72cjogxz 4771 40 1 1 CD cord-015369-72cjogxz 4771 41 ) ) -RRB- cord-015369-72cjogxz 4771 42 underwent undergo VBD cord-015369-72cjogxz 4771 43 stent stent NN cord-015369-72cjogxz 4771 44 placement placement NN cord-015369-72cjogxz 4771 45 due due IN cord-015369-72cjogxz 4771 46 to to IN cord-015369-72cjogxz 4771 47 severe severe JJ cord-015369-72cjogxz 4771 48 dysphagia dysphagia NN cord-015369-72cjogxz 4771 49 and and CC cord-015369-72cjogxz 4771 50 weight weight NN cord-015369-72cjogxz 4771 51 loss loss NN cord-015369-72cjogxz 4771 52 using use VBG cord-015369-72cjogxz 4771 53 self self NN cord-015369-72cjogxz 4771 54 expanding expand VBG cord-015369-72cjogxz 4771 55 plastic plastic NN cord-015369-72cjogxz 4771 56 stents stent NNS cord-015369-72cjogxz 4771 57 ( ( -LRB- cord-015369-72cjogxz 4771 58 n n CC cord-015369-72cjogxz 4771 59 ¼ ¼ NNP cord-015369-72cjogxz 4771 60 13 13 CD cord-015369-72cjogxz 4771 61 ) ) -RRB- cord-015369-72cjogxz 4771 62 or or CC cord-015369-72cjogxz 4771 63 covered cover VBN cord-015369-72cjogxz 4771 64 metal metal NN cord-015369-72cjogxz 4771 65 stents stent NNS cord-015369-72cjogxz 4771 66 ( ( -LRB- cord-015369-72cjogxz 4771 67 n n CC cord-015369-72cjogxz 4771 68 ¼ ¼ NNP cord-015369-72cjogxz 4771 69 25 25 CD cord-015369-72cjogxz 4771 70 ) ) -RRB- cord-015369-72cjogxz 4771 71 . . . cord-015369-72cjogxz 4772 1 Results result NNS cord-015369-72cjogxz 4772 2 . . . cord-015369-72cjogxz 4773 1 Stent stent NN cord-015369-72cjogxz 4773 2 placement placement NN cord-015369-72cjogxz 4773 3 led lead VBD cord-015369-72cjogxz 4773 4 to to IN cord-015369-72cjogxz 4773 5 an an DT cord-015369-72cjogxz 4773 6 instant instant JJ cord-015369-72cjogxz 4773 7 dysphagia dysphagia NN cord-015369-72cjogxz 4773 8 relief relief NN cord-015369-72cjogxz 4773 9 in in IN cord-015369-72cjogxz 4773 10 37 37 CD cord-015369-72cjogxz 4773 11 ( ( -LRB- cord-015369-72cjogxz 4773 12 97 97 CD cord-015369-72cjogxz 4773 13 % % NN cord-015369-72cjogxz 4773 14 ) ) -RRB- cord-015369-72cjogxz 4773 15 of of IN cord-015369-72cjogxz 4773 16 the the DT cord-015369-72cjogxz 4773 17 38 38 CD cord-015369-72cjogxz 4773 18 patients patient NNS cord-015369-72cjogxz 4773 19 . . . cord-015369-72cjogxz 4774 1 Dysphagia Dysphagia NNP cord-015369-72cjogxz 4774 2 scores score NNS cord-015369-72cjogxz 4774 3 were be VBD cord-015369-72cjogxz 4774 4 reduced reduce VBN cord-015369-72cjogxz 4774 5 from from IN cord-015369-72cjogxz 4774 6 median median JJ cord-015369-72cjogxz 4774 7 3.0 3.0 CD cord-015369-72cjogxz 4774 8 AE AE NNP cord-015369-72cjogxz 4774 9 0.5 0.5 CD cord-015369-72cjogxz 4774 10 before before IN cord-015369-72cjogxz 4774 11 stent stent NN cord-015369-72cjogxz 4774 12 placement placement NN cord-015369-72cjogxz 4774 13 to to IN cord-015369-72cjogxz 4774 14 0.5 0.5 CD cord-015369-72cjogxz 4774 15 AE AE NNP cord-015369-72cjogxz 4774 16 0.8 0.8 CD cord-015369-72cjogxz 4774 17 thereafter thereafter RB cord-015369-72cjogxz 4774 18 . . . cord-015369-72cjogxz 4775 1 Among among IN cord-015369-72cjogxz 4775 2 those those DT cord-015369-72cjogxz 4775 3 38 38 CD cord-015369-72cjogxz 4775 4 patients patient NNS cord-015369-72cjogxz 4775 5 , , , cord-015369-72cjogxz 4775 6 20 20 CD cord-015369-72cjogxz 4775 7 ( ( -LRB- cord-015369-72cjogxz 4775 8 52 52 CD cord-015369-72cjogxz 4775 9 % % NN cord-015369-72cjogxz 4775 10 ) ) -RRB- cord-015369-72cjogxz 4775 11 underwent undergo VBD cord-015369-72cjogxz 4775 12 resection resection NN cord-015369-72cjogxz 4775 13 of of IN cord-015369-72cjogxz 4775 14 the the DT cord-015369-72cjogxz 4775 15 tumor tumor NN cord-015369-72cjogxz 4775 16 after after IN cord-015369-72cjogxz 4775 17 completion completion NN cord-015369-72cjogxz 4775 18 of of IN cord-015369-72cjogxz 4775 19 the the DT cord-015369-72cjogxz 4775 20 neo neo NNP cord-015369-72cjogxz 4775 21 - - HYPH cord-015369-72cjogxz 4775 22 adjuvant adjuvant JJ cord-015369-72cjogxz 4775 23 therapy therapy NN cord-015369-72cjogxz 4775 24 , , , cord-015369-72cjogxz 4775 25 6 6 CD cord-015369-72cjogxz 4775 26 patients patient NNS cord-015369-72cjogxz 4775 27 ( ( -LRB- cord-015369-72cjogxz 4775 28 16 16 CD cord-015369-72cjogxz 4775 29 % % NN cord-015369-72cjogxz 4775 30 ) ) -RRB- cord-015369-72cjogxz 4775 31 underwent undergo VBD cord-015369-72cjogxz 4775 32 primary primary JJ cord-015369-72cjogxz 4775 33 resection resection NN cord-015369-72cjogxz 4775 34 without without IN cord-015369-72cjogxz 4775 35 receiving receive VBG cord-015369-72cjogxz 4775 36 chemotherapy chemotherapy NN cord-015369-72cjogxz 4775 37 and and CC cord-015369-72cjogxz 4775 38 12 12 CD cord-015369-72cjogxz 4775 39 patients patient NNS cord-015369-72cjogxz 4775 40 ( ( -LRB- cord-015369-72cjogxz 4775 41 32 32 CD cord-015369-72cjogxz 4775 42 % % NN cord-015369-72cjogxz 4775 43 ) ) -RRB- cord-015369-72cjogxz 4775 44 had have VBD cord-015369-72cjogxz 4775 45 only only RB cord-015369-72cjogxz 4775 46 chemo(radio)therapy chemo(radio)therapy NN cord-015369-72cjogxz 4775 47 but but CC cord-015369-72cjogxz 4775 48 no no DT cord-015369-72cjogxz 4775 49 surgery surgery NN cord-015369-72cjogxz 4775 50 . . . cord-015369-72cjogxz 4776 1 All all DT cord-015369-72cjogxz 4776 2 of of IN cord-015369-72cjogxz 4776 3 them -PRON- PRP cord-015369-72cjogxz 4776 4 were be VBD cord-015369-72cjogxz 4776 5 exclusively exclusively RB cord-015369-72cjogxz 4776 6 nourished nourish VBN cord-015369-72cjogxz 4776 7 orally orally RB cord-015369-72cjogxz 4776 8 at at IN cord-015369-72cjogxz 4776 9 least least JJS cord-015369-72cjogxz 4776 10 until until IN cord-015369-72cjogxz 4776 11 restaging restaging NN cord-015369-72cjogxz 4776 12 or or CC cord-015369-72cjogxz 4776 13 surgery surgery NN cord-015369-72cjogxz 4776 14 . . . cord-015369-72cjogxz 4777 1 Stent stent NN cord-015369-72cjogxz 4777 2 related related JJ cord-015369-72cjogxz 4777 3 complications complication NNS cord-015369-72cjogxz 4777 4 were be VBD cord-015369-72cjogxz 4777 5 observed observe VBN cord-015369-72cjogxz 4777 6 as as IN cord-015369-72cjogxz 4777 7 perforation perforation NN cord-015369-72cjogxz 4777 8 at at IN cord-015369-72cjogxz 4777 9 stent stent NN cord-015369-72cjogxz 4777 10 placement placement NN cord-015369-72cjogxz 4777 11 ( ( -LRB- cord-015369-72cjogxz 4777 12 n n NNP cord-015369-72cjogxz 4777 13 ¼ ¼ NNP cord-015369-72cjogxz 4777 14 1 1 CD cord-015369-72cjogxz 4777 15 ) ) -RRB- cord-015369-72cjogxz 4777 16 , , , cord-015369-72cjogxz 4777 17 mediastinitis mediastinitis NNP cord-015369-72cjogxz 4777 18 ( ( -LRB- cord-015369-72cjogxz 4777 19 n n NNP cord-015369-72cjogxz 4777 20 ¼ ¼ NNP cord-015369-72cjogxz 4777 21 1 1 CD cord-015369-72cjogxz 4777 22 ) ) -RRB- cord-015369-72cjogxz 4777 23 , , , cord-015369-72cjogxz 4777 24 tracheo tracheo NN cord-015369-72cjogxz 4777 25 - - HYPH cord-015369-72cjogxz 4777 26 esophageal esophageal JJ cord-015369-72cjogxz 4777 27 fistula fistula NN cord-015369-72cjogxz 4777 28 ( ( -LRB- cord-015369-72cjogxz 4777 29 n n NN cord-015369-72cjogxz 4777 30 ¼ ¼ NNP cord-015369-72cjogxz 4777 31 2 2 CD cord-015369-72cjogxz 4777 32 ) ) -RRB- cord-015369-72cjogxz 4777 33 , , , cord-015369-72cjogxz 4777 34 bleeding bleed VBG cord-015369-72cjogxz 4777 35 ( ( -LRB- cord-015369-72cjogxz 4777 36 n n NN cord-015369-72cjogxz 4777 37 ¼ ¼ NNP cord-015369-72cjogxz 4777 38 1 1 CD cord-015369-72cjogxz 4777 39 ) ) -RRB- cord-015369-72cjogxz 4777 40 and and CC cord-015369-72cjogxz 4777 41 jejunal jejunal JJ cord-015369-72cjogxz 4777 42 perforation perforation NN cord-015369-72cjogxz 4777 43 caused cause VBN cord-015369-72cjogxz 4777 44 by by IN cord-015369-72cjogxz 4777 45 a a DT cord-015369-72cjogxz 4777 46 migrated migrate VBN cord-015369-72cjogxz 4777 47 stent stent NN cord-015369-72cjogxz 4777 48 ( ( -LRB- cord-015369-72cjogxz 4777 49 n n NNP cord-015369-72cjogxz 4777 50 ¼ ¼ NNP cord-015369-72cjogxz 4777 51 1 1 CD cord-015369-72cjogxz 4777 52 ) ) -RRB- cord-015369-72cjogxz 4777 53 . . . cord-015369-72cjogxz 4778 1 Four four CD cord-015369-72cjogxz 4778 2 patients patient NNS cord-015369-72cjogxz 4778 3 underwent undergo VBD cord-015369-72cjogxz 4778 4 placement placement NN cord-015369-72cjogxz 4778 5 of of IN cord-015369-72cjogxz 4778 6 a a DT cord-015369-72cjogxz 4778 7 second second JJ cord-015369-72cjogxz 4778 8 stent stent NN cord-015369-72cjogxz 4778 9 and and CC cord-015369-72cjogxz 4778 10 1 1 CD cord-015369-72cjogxz 4778 11 patient patient NN cord-015369-72cjogxz 4778 12 had have VBD cord-015369-72cjogxz 4778 13 bouginage bouginage NN cord-015369-72cjogxz 4778 14 due due IN cord-015369-72cjogxz 4778 15 to to IN cord-015369-72cjogxz 4778 16 stent stent NN cord-015369-72cjogxz 4778 17 migration migration NN cord-015369-72cjogxz 4778 18 ( ( -LRB- cord-015369-72cjogxz 4778 19 n n NN cord-015369-72cjogxz 4778 20 ¼ ¼ NNP cord-015369-72cjogxz 4778 21 5 5 CD cord-015369-72cjogxz 4778 22 ) ) -RRB- cord-015369-72cjogxz 4778 23 . . . cord-015369-72cjogxz 4779 1 Conclusions conclusion NNS cord-015369-72cjogxz 4779 2 . . . cord-015369-72cjogxz 4780 1 Placement placement NN cord-015369-72cjogxz 4780 2 of of IN cord-015369-72cjogxz 4780 3 self self NN cord-015369-72cjogxz 4780 4 - - HYPH cord-015369-72cjogxz 4780 5 expanding expand VBG cord-015369-72cjogxz 4780 6 stents stent NNS cord-015369-72cjogxz 4780 7 is be VBZ cord-015369-72cjogxz 4780 8 highly highly RB cord-015369-72cjogxz 4780 9 effective effective JJ cord-015369-72cjogxz 4780 10 for for IN cord-015369-72cjogxz 4780 11 instant instant JJ cord-015369-72cjogxz 4780 12 dysphagia dysphagia NN cord-015369-72cjogxz 4780 13 relief relief NN cord-015369-72cjogxz 4780 14 enabling enable VBG cord-015369-72cjogxz 4780 15 adequate adequate JJ cord-015369-72cjogxz 4780 16 oral oral JJ cord-015369-72cjogxz 4780 17 nutrition nutrition NN cord-015369-72cjogxz 4780 18 during during IN cord-015369-72cjogxz 4780 19 neo neo NNP cord-015369-72cjogxz 4780 20 - - HYPH cord-015369-72cjogxz 4780 21 adjuvant adjuvant JJ cord-015369-72cjogxz 4780 22 therapy therapy NN cord-015369-72cjogxz 4780 23 , , , cord-015369-72cjogxz 4780 24 but but CC cord-015369-72cjogxz 4780 25 is be VBZ cord-015369-72cjogxz 4780 26 limited limit VBN cord-015369-72cjogxz 4780 27 by by IN cord-015369-72cjogxz 4780 28 a a DT cord-015369-72cjogxz 4780 29 high high JJ cord-015369-72cjogxz 4780 30 re re NN cord-015369-72cjogxz 4780 31 - - NN cord-015369-72cjogxz 4780 32 intervention intervention NN cord-015369-72cjogxz 4780 33 rate rate NN cord-015369-72cjogxz 4780 34 . . . cord-015369-72cjogxz 4781 1 Background background NN cord-015369-72cjogxz 4781 2 . . . cord-015369-72cjogxz 4782 1 Anastomotic anastomotic JJ cord-015369-72cjogxz 4782 2 leak leak NN cord-015369-72cjogxz 4782 3 is be VBZ cord-015369-72cjogxz 4782 4 a a DT cord-015369-72cjogxz 4782 5 potentially potentially RB cord-015369-72cjogxz 4782 6 life life NN cord-015369-72cjogxz 4782 7 - - HYPH cord-015369-72cjogxz 4782 8 threatening threaten VBG cord-015369-72cjogxz 4782 9 complication complication NN cord-015369-72cjogxz 4782 10 after after IN cord-015369-72cjogxz 4782 11 upper upper JJ cord-015369-72cjogxz 4782 12 gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 4782 13 resektions resektion NNS cord-015369-72cjogxz 4782 14 and and CC cord-015369-72cjogxz 4782 15 bariatric bariatric JJ cord-015369-72cjogxz 4782 16 surgery surgery NN cord-015369-72cjogxz 4782 17 requiring require VBG cord-015369-72cjogxz 4782 18 long long RB cord-015369-72cjogxz 4782 19 , , , cord-015369-72cjogxz 4782 20 cost cost NN cord-015369-72cjogxz 4782 21 - - HYPH cord-015369-72cjogxz 4782 22 intensive intensive JJ cord-015369-72cjogxz 4782 23 and and CC cord-015369-72cjogxz 4782 24 frequently frequently RB cord-015369-72cjogxz 4782 25 failed fail VBD cord-015369-72cjogxz 4782 26 treatment treatment NN cord-015369-72cjogxz 4782 27 . . . cord-015369-72cjogxz 4783 1 This this DT cord-015369-72cjogxz 4783 2 study study NN cord-015369-72cjogxz 4783 3 has have VBZ cord-015369-72cjogxz 4783 4 been be VBN cord-015369-72cjogxz 4783 5 undertaken undertake VBN cord-015369-72cjogxz 4783 6 to to TO cord-015369-72cjogxz 4783 7 evaluate evaluate VB cord-015369-72cjogxz 4783 8 , , , cord-015369-72cjogxz 4783 9 whether whether IN cord-015369-72cjogxz 4783 10 endoscopic endoscopic NNS cord-015369-72cjogxz 4783 11 sealing seal VBG cord-015369-72cjogxz 4783 12 with with IN cord-015369-72cjogxz 4783 13 autologous autologous JJ cord-015369-72cjogxz 4783 14 fibrin fibrin NN cord-015369-72cjogxz 4783 15 glue glue NN cord-015369-72cjogxz 4783 16 is be VBZ cord-015369-72cjogxz 4783 17 an an DT cord-015369-72cjogxz 4783 18 effective effective JJ cord-015369-72cjogxz 4783 19 treatment treatment NN cord-015369-72cjogxz 4783 20 for for IN cord-015369-72cjogxz 4783 21 persistent persistent JJ cord-015369-72cjogxz 4783 22 postoperative postoperative JJ cord-015369-72cjogxz 4783 23 fistula fistula NN cord-015369-72cjogxz 4783 24 . . . cord-015369-72cjogxz 4784 1 Methods method NNS cord-015369-72cjogxz 4784 2 . . . cord-015369-72cjogxz 4785 1 Between between IN cord-015369-72cjogxz 4785 2 September September NNP cord-015369-72cjogxz 4785 3 2007 2007 CD cord-015369-72cjogxz 4785 4 and and CC cord-015369-72cjogxz 4785 5 January January NNP cord-015369-72cjogxz 4785 6 2009 2009 CD cord-015369-72cjogxz 4785 7 16 16 CD cord-015369-72cjogxz 4785 8 patients patient NNS cord-015369-72cjogxz 4785 9 who who WP cord-015369-72cjogxz 4785 10 developed develop VBD cord-015369-72cjogxz 4785 11 non non JJ cord-015369-72cjogxz 4785 12 - - JJ cord-015369-72cjogxz 4785 13 healing healing JJ cord-015369-72cjogxz 4785 14 upper upper JJ cord-015369-72cjogxz 4785 15 gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 4785 16 leaks leak NNS cord-015369-72cjogxz 4785 17 after after IN cord-015369-72cjogxz 4785 18 oncologic oncologic NNP cord-015369-72cjogxz 4785 19 ( ( -LRB- cord-015369-72cjogxz 4785 20 n n NN cord-015369-72cjogxz 4785 21 ¼ ¼ NNP cord-015369-72cjogxz 4785 22 4 4 CD cord-015369-72cjogxz 4785 23 ) ) -RRB- cord-015369-72cjogxz 4785 24 and and CC cord-015369-72cjogxz 4785 25 non non JJ cord-015369-72cjogxz 4785 26 - - JJ cord-015369-72cjogxz 4785 27 oncologic oncologic JJ cord-015369-72cjogxz 4785 28 oesophageal oesophageal NN cord-015369-72cjogxz 4785 29 ( ( -LRB- cord-015369-72cjogxz 4785 30 n n NN cord-015369-72cjogxz 4785 31 ¼ ¼ NNP cord-015369-72cjogxz 4785 32 3 3 CD cord-015369-72cjogxz 4785 33 ) ) -RRB- cord-015369-72cjogxz 4785 34 , , , cord-015369-72cjogxz 4785 35 gastric gastric JJ cord-015369-72cjogxz 4785 36 ( ( -LRB- cord-015369-72cjogxz 4785 37 n n NN cord-015369-72cjogxz 4785 38 ¼ ¼ NNP cord-015369-72cjogxz 4785 39 1 1 CD cord-015369-72cjogxz 4785 40 ) ) -RRB- cord-015369-72cjogxz 4785 41 or or CC cord-015369-72cjogxz 4785 42 bariatric bariatric JJ cord-015369-72cjogxz 4785 43 ( ( -LRB- cord-015369-72cjogxz 4785 44 n n NN cord-015369-72cjogxz 4785 45 ¼ ¼ NNP cord-015369-72cjogxz 4785 46 8) 8) NNP cord-015369-72cjogxz 4785 47 surgery surgery NN cord-015369-72cjogxz 4785 48 were be VBD cord-015369-72cjogxz 4785 49 treated treat VBN cord-015369-72cjogxz 4785 50 by by IN cord-015369-72cjogxz 4785 51 endoscopic endoscopic NNS cord-015369-72cjogxz 4785 52 Vivostat Vivostat NNP cord-015369-72cjogxz 4785 53 + + CC cord-015369-72cjogxz 4785 54 autologous autologous JJ cord-015369-72cjogxz 4785 55 fibrin fibrin NN cord-015369-72cjogxz 4785 56 sealing sealing NN cord-015369-72cjogxz 4785 57 . . . cord-015369-72cjogxz 4786 1 Fibrin fibrin NN cord-015369-72cjogxz 4786 2 sealant sealant NN cord-015369-72cjogxz 4786 3 was be VBD cord-015369-72cjogxz 4786 4 applied apply VBN cord-015369-72cjogxz 4786 5 in in IN cord-015369-72cjogxz 4786 6 patients patient NNS cord-015369-72cjogxz 4786 7 without without IN cord-015369-72cjogxz 4786 8 systemic systemic JJ cord-015369-72cjogxz 4786 9 or or CC cord-015369-72cjogxz 4786 10 advanced advanced JJ cord-015369-72cjogxz 4786 11 local local JJ cord-015369-72cjogxz 4786 12 sings sing NNS cord-015369-72cjogxz 4786 13 of of IN cord-015369-72cjogxz 4786 14 infection infection NN cord-015369-72cjogxz 4786 15 with with IN cord-015369-72cjogxz 4786 16 a a DT cord-015369-72cjogxz 4786 17 sufficient sufficient JJ cord-015369-72cjogxz 4786 18 external external JJ cord-015369-72cjogxz 4786 19 drainage drainage NN cord-015369-72cjogxz 4786 20 of of IN cord-015369-72cjogxz 4786 21 leakage leakage NN cord-015369-72cjogxz 4786 22 site site NN cord-015369-72cjogxz 4786 23 . . . cord-015369-72cjogxz 4787 1 Location location NN cord-015369-72cjogxz 4787 2 was be VBD cord-015369-72cjogxz 4787 3 cervical cervical JJ cord-015369-72cjogxz 4787 4 ( ( -LRB- cord-015369-72cjogxz 4787 5 n n NN cord-015369-72cjogxz 4787 6 ¼ ¼ NNP cord-015369-72cjogxz 4787 7 1 1 CD cord-015369-72cjogxz 4787 8 ) ) -RRB- cord-015369-72cjogxz 4787 9 , , , cord-015369-72cjogxz 4787 10 intrathoracic intrathoracic JJ cord-015369-72cjogxz 4787 11 ( ( -LRB- cord-015369-72cjogxz 4787 12 n n NN cord-015369-72cjogxz 4787 13 ¼ ¼ NNP cord-015369-72cjogxz 4787 14 4 4 CD cord-015369-72cjogxz 4787 15 ) ) -RRB- cord-015369-72cjogxz 4787 16 and and CC cord-015369-72cjogxz 4787 17 abdominal abdominal JJ cord-015369-72cjogxz 4787 18 ( ( -LRB- cord-015369-72cjogxz 4787 19 n n NN cord-015369-72cjogxz 4787 20 ¼ ¼ NNP cord-015369-72cjogxz 4787 21 11 11 CD cord-015369-72cjogxz 4787 22 ) ) -RRB- cord-015369-72cjogxz 4787 23 . . . cord-015369-72cjogxz 4788 1 Previous previous JJ cord-015369-72cjogxz 4788 2 leak leak NN cord-015369-72cjogxz 4788 3 treatment treatment NN cord-015369-72cjogxz 4788 4 included include VBD cord-015369-72cjogxz 4788 5 surgery surgery NN cord-015369-72cjogxz 4788 6 , , , cord-015369-72cjogxz 4788 7 external external JJ cord-015369-72cjogxz 4788 8 drainage drainage NN cord-015369-72cjogxz 4788 9 or or CC cord-015369-72cjogxz 4788 10 / / SYM cord-015369-72cjogxz 4788 11 and and CC cord-015369-72cjogxz 4788 12 endoscopic endoscopic NNS cord-015369-72cjogxz 4788 13 stenting stenting NN cord-015369-72cjogxz 4788 14 . . . cord-015369-72cjogxz 4789 1 Endoscopic Endoscopic NNS cord-015369-72cjogxz 4789 2 sealing sealing NN cord-015369-72cjogxz 4789 3 occured occur VBD cord-015369-72cjogxz 4789 4 after after IN cord-015369-72cjogxz 4789 5 a a DT cord-015369-72cjogxz 4789 6 median median JJ cord-015369-72cjogxz 4789 7 interval interval NN cord-015369-72cjogxz 4789 8 of of IN cord-015369-72cjogxz 4789 9 31 31 CD cord-015369-72cjogxz 4789 10 days day NNS cord-015369-72cjogxz 4789 11 ( ( -LRB- cord-015369-72cjogxz 4789 12 range range NNP cord-015369-72cjogxz 4789 13 1 1 CD cord-015369-72cjogxz 4789 14 - - SYM cord-015369-72cjogxz 4789 15 414 414 CD cord-015369-72cjogxz 4789 16 ) ) -RRB- cord-015369-72cjogxz 4789 17 after after IN cord-015369-72cjogxz 4789 18 primary primary JJ cord-015369-72cjogxz 4789 19 surgery surgery NN cord-015369-72cjogxz 4789 20 . . . cord-015369-72cjogxz 4790 1 Results result NNS cord-015369-72cjogxz 4790 2 . . . cord-015369-72cjogxz 4791 1 Fourteen fourteen CD cord-015369-72cjogxz 4791 2 of of IN cord-015369-72cjogxz 4791 3 sixteen sixteen CD cord-015369-72cjogxz 4791 4 patients patient NNS cord-015369-72cjogxz 4791 5 had have VBD cord-015369-72cjogxz 4791 6 complete complete JJ cord-015369-72cjogxz 4791 7 healing healing NN cord-015369-72cjogxz 4791 8 of of IN cord-015369-72cjogxz 4791 9 the the DT cord-015369-72cjogxz 4791 10 anastomotic anastomotic JJ cord-015369-72cjogxz 4791 11 leak leak NN cord-015369-72cjogxz 4791 12 or or CC cord-015369-72cjogxz 4791 13 fistula fistula NN cord-015369-72cjogxz 4791 14 after after IN cord-015369-72cjogxz 4791 15 one one CD cord-015369-72cjogxz 4791 16 ( ( -LRB- cord-015369-72cjogxz 4791 17 7 7 CD cord-015369-72cjogxz 4791 18 patients patient NNS cord-015369-72cjogxz 4791 19 ) ) -RRB- cord-015369-72cjogxz 4791 20 , , , cord-015369-72cjogxz 4791 21 two two CD cord-015369-72cjogxz 4791 22 ( ( -LRB- cord-015369-72cjogxz 4791 23 4 4 CD cord-015369-72cjogxz 4791 24 patients patient NNS cord-015369-72cjogxz 4791 25 ) ) -RRB- cord-015369-72cjogxz 4791 26 , , , cord-015369-72cjogxz 4791 27 tree tree NN cord-015369-72cjogxz 4791 28 ( ( -LRB- cord-015369-72cjogxz 4791 29 2 2 CD cord-015369-72cjogxz 4791 30 patients patient NNS cord-015369-72cjogxz 4791 31 ) ) -RRB- cord-015369-72cjogxz 4791 32 or or CC cord-015369-72cjogxz 4791 33 five five CD cord-015369-72cjogxz 4791 34 ( ( -LRB- cord-015369-72cjogxz 4791 35 1 1 CD cord-015369-72cjogxz 4791 36 patient patient NN cord-015369-72cjogxz 4791 37 ) ) -RRB- cord-015369-72cjogxz 4791 38 sealing seal VBG cord-015369-72cjogxz 4791 39 procedures procedure NNS cord-015369-72cjogxz 4791 40 . . . cord-015369-72cjogxz 4792 1 In in IN cord-015369-72cjogxz 4792 2 six six CD cord-015369-72cjogxz 4792 3 procedures procedure NNS cord-015369-72cjogxz 4792 4 sealing seal VBG cord-015369-72cjogxz 4792 5 was be VBD cord-015369-72cjogxz 4792 6 completed complete VBN cord-015369-72cjogxz 4792 7 by by IN cord-015369-72cjogxz 4792 8 simultaneous simultaneous JJ cord-015369-72cjogxz 4792 9 implantation implantation NN cord-015369-72cjogxz 4792 10 of of IN cord-015369-72cjogxz 4792 11 a a DT cord-015369-72cjogxz 4792 12 stent stent NN cord-015369-72cjogxz 4792 13 . . . cord-015369-72cjogxz 4793 1 In in IN cord-015369-72cjogxz 4793 2 two two CD cord-015369-72cjogxz 4793 3 patients patient NNS cord-015369-72cjogxz 4793 4 treatment treatment NN cord-015369-72cjogxz 4793 5 failed fail VBD cord-015369-72cjogxz 4793 6 and and CC cord-015369-72cjogxz 4793 7 the the DT cord-015369-72cjogxz 4793 8 healing healing NN cord-015369-72cjogxz 4793 9 of of IN cord-015369-72cjogxz 4793 10 the the DT cord-015369-72cjogxz 4793 11 abdominal abdominal JJ cord-015369-72cjogxz 4793 12 fistula fistula NN cord-015369-72cjogxz 4793 13 was be VBD cord-015369-72cjogxz 4793 14 achieved achieve VBN cord-015369-72cjogxz 4793 15 by by IN cord-015369-72cjogxz 4793 16 following follow VBG cord-015369-72cjogxz 4793 17 insertion insertion NN cord-015369-72cjogxz 4793 18 of of IN cord-015369-72cjogxz 4793 19 a a DT cord-015369-72cjogxz 4793 20 stent stent NN cord-015369-72cjogxz 4793 21 on on IN cord-015369-72cjogxz 4793 22 the the DT cord-015369-72cjogxz 4793 23 leakage leakage NN cord-015369-72cjogxz 4793 24 site site NN cord-015369-72cjogxz 4793 25 . . . cord-015369-72cjogxz 4794 1 Conclusions conclusion NNS cord-015369-72cjogxz 4794 2 . . . cord-015369-72cjogxz 4795 1 Autologous autologous JJ cord-015369-72cjogxz 4795 2 fibrin fibrin NN cord-015369-72cjogxz 4795 3 sealing sealing NN cord-015369-72cjogxz 4795 4 could could MD cord-015369-72cjogxz 4795 5 be be VB cord-015369-72cjogxz 4795 6 successfully successfully RB cord-015369-72cjogxz 4795 7 used use VBN cord-015369-72cjogxz 4795 8 for for IN cord-015369-72cjogxz 4795 9 management management NN cord-015369-72cjogxz 4795 10 of of IN cord-015369-72cjogxz 4795 11 persistent persistent JJ cord-015369-72cjogxz 4795 12 upper upper JJ cord-015369-72cjogxz 4795 13 gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 4795 14 fistula fistula NN cord-015369-72cjogxz 4795 15 and and CC cord-015369-72cjogxz 4795 16 promotes promote VBZ cord-015369-72cjogxz 4795 17 healing healing NN cord-015369-72cjogxz 4795 18 . . . cord-015369-72cjogxz 4796 1 Results result NNS cord-015369-72cjogxz 4796 2 after after IN cord-015369-72cjogxz 4796 3 different different JJ cord-015369-72cjogxz 4796 4 treatment treatment NN cord-015369-72cjogxz 4796 5 modalities modality NNS cord-015369-72cjogxz 4796 6 for for IN cord-015369-72cjogxz 4796 7 Achalasia Achalasia NNP cord-015369-72cjogxz 4796 8 Background Background NNP cord-015369-72cjogxz 4796 9 . . . cord-015369-72cjogxz 4797 1 Achalasia Achalasia NNP cord-015369-72cjogxz 4797 2 is be VBZ cord-015369-72cjogxz 4797 3 an an DT cord-015369-72cjogxz 4797 4 esophageal esophageal JJ cord-015369-72cjogxz 4797 5 functional functional JJ cord-015369-72cjogxz 4797 6 disorder disorder NN cord-015369-72cjogxz 4797 7 with with IN cord-015369-72cjogxz 4797 8 esophageal esophageal JJ cord-015369-72cjogxz 4797 9 body body NN cord-015369-72cjogxz 4797 10 amotility amotility NN cord-015369-72cjogxz 4797 11 and and CC cord-015369-72cjogxz 4797 12 impaired impair VBN cord-015369-72cjogxz 4797 13 lower low JJR cord-015369-72cjogxz 4797 14 esophageal esophageal JJ cord-015369-72cjogxz 4797 15 sphincter sphincter NN cord-015369-72cjogxz 4797 16 ( ( -LRB- cord-015369-72cjogxz 4797 17 LES LES NNP cord-015369-72cjogxz 4797 18 ) ) -RRB- cord-015369-72cjogxz 4797 19 relaxation relaxation NN cord-015369-72cjogxz 4797 20 causing cause VBG cord-015369-72cjogxz 4797 21 dysphagia dysphagia NN cord-015369-72cjogxz 4797 22 , , , cord-015369-72cjogxz 4797 23 heartburn heartburn NN cord-015369-72cjogxz 4797 24 and and CC cord-015369-72cjogxz 4797 25 regurgitation regurgitation NN cord-015369-72cjogxz 4797 26 . . . cord-015369-72cjogxz 4798 1 Methods method NNS cord-015369-72cjogxz 4798 2 . . . cord-015369-72cjogxz 4799 1 Retrospective retrospective JJ cord-015369-72cjogxz 4799 2 analysis analysis NN cord-015369-72cjogxz 4799 3 of of IN cord-015369-72cjogxz 4799 4 105 105 CD cord-015369-72cjogxz 4799 5 patients patient NNS cord-015369-72cjogxz 4799 6 with with IN cord-015369-72cjogxz 4799 7 manometrically manometrically RB cord-015369-72cjogxz 4799 8 proven prove VBN cord-015369-72cjogxz 4799 9 achalasia achalasia NN cord-015369-72cjogxz 4799 10 ( ( -LRB- cord-015369-72cjogxz 4799 11 50 50 CD cord-015369-72cjogxz 4799 12 females female NNS cord-015369-72cjogxz 4799 13 ; ; : cord-015369-72cjogxz 4799 14 48 48 CD cord-015369-72cjogxz 4799 15 AE AE NNP cord-015369-72cjogxz 4799 16 19 19 CD cord-015369-72cjogxz 4799 17 years year NNS cord-015369-72cjogxz 4799 18 ) ) -RRB- cord-015369-72cjogxz 4799 19 ( ( -LRB- cord-015369-72cjogxz 4799 20 1995 1995 CD cord-015369-72cjogxz 4799 21 ) ) -RRB- cord-015369-72cjogxz 4799 22 ( ( -LRB- cord-015369-72cjogxz 4799 23 1996 1996 CD cord-015369-72cjogxz 4799 24 ) ) -RRB- cord-015369-72cjogxz 4799 25 ( ( -LRB- cord-015369-72cjogxz 4799 26 1997 1997 CD cord-015369-72cjogxz 4799 27 ) ) -RRB- cord-015369-72cjogxz 4799 28 ( ( -LRB- cord-015369-72cjogxz 4799 29 1998 1998 CD cord-015369-72cjogxz 4799 30 ) ) -RRB- cord-015369-72cjogxz 4799 31 ( ( -LRB- cord-015369-72cjogxz 4799 32 1999 1999 CD cord-015369-72cjogxz 4799 33 ) ) -RRB- cord-015369-72cjogxz 4799 34 ( ( -LRB- cord-015369-72cjogxz 4799 35 2000 2000 CD cord-015369-72cjogxz 4799 36 ) ) -RRB- cord-015369-72cjogxz 4799 37 ( ( -LRB- cord-015369-72cjogxz 4799 38 2001 2001 CD cord-015369-72cjogxz 4799 39 ) ) -RRB- cord-015369-72cjogxz 4799 40 ( ( -LRB- cord-015369-72cjogxz 4799 41 2002 2002 CD cord-015369-72cjogxz 4799 42 ) ) -RRB- cord-015369-72cjogxz 4799 43 ( ( -LRB- cord-015369-72cjogxz 4799 44 2003 2003 CD cord-015369-72cjogxz 4799 45 ) ) -RRB- cord-015369-72cjogxz 4799 46 ( ( -LRB- cord-015369-72cjogxz 4799 47 2004 2004 CD cord-015369-72cjogxz 4799 48 ) ) -RRB- cord-015369-72cjogxz 4799 49 ( ( -LRB- cord-015369-72cjogxz 4799 50 2005 2005 CD cord-015369-72cjogxz 4799 51 ) ) -RRB- cord-015369-72cjogxz 4799 52 ( ( -LRB- cord-015369-72cjogxz 4799 53 2006 2006 CD cord-015369-72cjogxz 4799 54 ) ) -RRB- cord-015369-72cjogxz 4799 55 . . . cord-015369-72cjogxz 4800 1 Management management NN cord-015369-72cjogxz 4800 2 included include VBD cord-015369-72cjogxz 4800 3 primary primary JJ cord-015369-72cjogxz 4800 4 dilatation dilatation NN cord-015369-72cjogxz 4800 5 ( ( -LRB- cord-015369-72cjogxz 4800 6 Stark stark JJ cord-015369-72cjogxz 4800 7 dilator dilator NN cord-015369-72cjogxz 4800 8 ; ; : cord-015369-72cjogxz 4800 9 n n NN cord-015369-72cjogxz 4800 10 ¼ ¼ NNP cord-015369-72cjogxz 4800 11 41 41 CD cord-015369-72cjogxz 4800 12 ) ) -RRB- cord-015369-72cjogxz 4800 13 , , , cord-015369-72cjogxz 4800 14 primary primary JJ cord-015369-72cjogxz 4800 15 laparoscopic laparoscopic JJ cord-015369-72cjogxz 4800 16 myotomy myotomy NN cord-015369-72cjogxz 4800 17 and and CC cord-015369-72cjogxz 4800 18 anterior anterior NNP cord-015369-72cjogxz 4800 19 fundoplication fundoplication NNP cord-015369-72cjogxz 4800 20 ( ( -LRB- cord-015369-72cjogxz 4800 21 n n NN cord-015369-72cjogxz 4800 22 ¼ ¼ NNP cord-015369-72cjogxz 4800 23 11 11 CD cord-015369-72cjogxz 4800 24 ) ) -RRB- cord-015369-72cjogxz 4800 25 , , , cord-015369-72cjogxz 4800 26 secondary secondary JJ cord-015369-72cjogxz 4800 27 myotomy myotomy NN cord-015369-72cjogxz 4800 28 following follow VBG cord-015369-72cjogxz 4800 29 dilatation dilatation NN cord-015369-72cjogxz 4800 30 ( ( -LRB- cord-015369-72cjogxz 4800 31 n n CC cord-015369-72cjogxz 4800 32 ¼ ¼ NNP cord-015369-72cjogxz 4800 33 8) 8) NNP cord-015369-72cjogxz 4800 34 , , , cord-015369-72cjogxz 4800 35 a a DT cord-015369-72cjogxz 4800 36 mix mix NN cord-015369-72cjogxz 4800 37 of of IN cord-015369-72cjogxz 4800 38 botox botox NNP cord-015369-72cjogxz 4800 39 administration administration NN cord-015369-72cjogxz 4800 40 and and CC cord-015369-72cjogxz 4800 41 dilatation dilatation NN cord-015369-72cjogxz 4800 42 ( ( -LRB- cord-015369-72cjogxz 4800 43 n n NN cord-015369-72cjogxz 4800 44 ¼ ¼ NNP cord-015369-72cjogxz 4800 45 9 9 CD cord-015369-72cjogxz 4800 46 ) ) -RRB- cord-015369-72cjogxz 4800 47 and and CC cord-015369-72cjogxz 4800 48 is be VBZ cord-015369-72cjogxz 4800 49 unknown unknown JJ cord-015369-72cjogxz 4800 50 in in IN cord-015369-72cjogxz 4800 51 36 36 CD cord-015369-72cjogxz 4800 52 patients patient NNS cord-015369-72cjogxz 4800 53 . . . cord-015369-72cjogxz 4801 1 Results result NNS cord-015369-72cjogxz 4801 2 . . . cord-015369-72cjogxz 4802 1 Follow follow VB cord-015369-72cjogxz 4802 2 up up RP cord-015369-72cjogxz 4803 1 manometry manometry NNP cord-015369-72cjogxz 4803 2 was be VBD cord-015369-72cjogxz 4803 3 available available JJ cord-015369-72cjogxz 4803 4 in in IN cord-015369-72cjogxz 4803 5 12/41 12/41 CD cord-015369-72cjogxz 4803 6 , , , cord-015369-72cjogxz 4803 7 7/11 7/11 CD cord-015369-72cjogxz 4803 8 and and CC cord-015369-72cjogxz 4803 9 4/7 4/7 CD cord-015369-72cjogxz 4803 10 patients patient NNS cord-015369-72cjogxz 4803 11 after after IN cord-015369-72cjogxz 4803 12 dilatation dilatation NN cord-015369-72cjogxz 4803 13 , , , cord-015369-72cjogxz 4803 14 primary primary JJ cord-015369-72cjogxz 4803 15 and and CC cord-015369-72cjogxz 4803 16 secondary secondary JJ cord-015369-72cjogxz 4803 17 myotomy myotomy NN cord-015369-72cjogxz 4803 18 , , , cord-015369-72cjogxz 4803 19 respectively respectively RB cord-015369-72cjogxz 4803 20 . . . cord-015369-72cjogxz 4804 1 After after IN cord-015369-72cjogxz 4804 2 dilatation dilatation NN cord-015369-72cjogxz 4804 3 LES LES NNP cord-015369-72cjogxz 4804 4 resting rest VBG cord-015369-72cjogxz 4804 5 pressure pressure NN cord-015369-72cjogxz 4804 6 decreased decrease VBD cord-015369-72cjogxz 4804 7 from from IN cord-015369-72cjogxz 4804 8 27.09 27.09 CD cord-015369-72cjogxz 4804 9 ( ( -LRB- cord-015369-72cjogxz 4804 10 22.96 22.96 CD cord-015369-72cjogxz 4804 11 ; ; : cord-015369-72cjogxz 4804 12 31.22 31.22 CD cord-015369-72cjogxz 4804 13 ; ; : cord-015369-72cjogxz 4804 14 95 95 CD cord-015369-72cjogxz 4804 15 % % NN cord-015369-72cjogxz 4804 16 CI CI NNP cord-015369-72cjogxz 4804 17 ) ) -RRB- cord-015369-72cjogxz 4804 18 to to IN cord-015369-72cjogxz 4804 19 18.95 18.95 CD cord-015369-72cjogxz 4804 20 ( ( -LRB- cord-015369-72cjogxz 4804 21 15.13 15.13 CD cord-015369-72cjogxz 4804 22 ; ; : cord-015369-72cjogxz 4804 23 22.7 22.7 CD cord-015369-72cjogxz 4804 24 Conclusions conclusion NNS cord-015369-72cjogxz 4804 25 . . . cord-015369-72cjogxz 4805 1 Primary primary JJ cord-015369-72cjogxz 4805 2 dilatation dilatation NN cord-015369-72cjogxz 4805 3 is be VBZ cord-015369-72cjogxz 4805 4 recommended recommend VBN cord-015369-72cjogxz 4805 5 for for IN cord-015369-72cjogxz 4805 6 Achalasia Achalasia NNP cord-015369-72cjogxz 4805 7 , , , cord-015369-72cjogxz 4805 8 primary primary JJ cord-015369-72cjogxz 4805 9 myotomy myotomy NN cord-015369-72cjogxz 4805 10 may may MD cord-015369-72cjogxz 4805 11 be be VB cord-015369-72cjogxz 4805 12 considered consider VBN cord-015369-72cjogxz 4805 13 in in IN cord-015369-72cjogxz 4805 14 younger young JJR cord-015369-72cjogxz 4805 15 patients patient NNS cord-015369-72cjogxz 4805 16 . . . cord-015369-72cjogxz 4806 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4806 2 . . . cord-015369-72cjogxz 4807 1 Osteosarkome Osteosarkome NNP cord-015369-72cjogxz 4807 2 sind sind NNPS cord-015369-72cjogxz 4807 3 die die VBP cord-015369-72cjogxz 4807 4 häufigsten häufigsten NNP cord-015369-72cjogxz 4807 5 primär primär NNP cord-015369-72cjogxz 4807 6 malignen malignen NNP cord-015369-72cjogxz 4807 7 , , , cord-015369-72cjogxz 4807 8 nicht nicht NNP cord-015369-72cjogxz 4807 9 hämatopoetischen hämatopoetischen NNP cord-015369-72cjogxz 4807 10 Tumoren Tumoren NNP cord-015369-72cjogxz 4807 11 des des NNP cord-015369-72cjogxz 4807 12 Knochens Knochens NNP cord-015369-72cjogxz 4807 13 . . . cord-015369-72cjogxz 4808 1 Ihre Ihre NNP cord-015369-72cjogxz 4808 2 Inzidenz Inzidenz NNP cord-015369-72cjogxz 4808 3 beträgt beträgt NN cord-015369-72cjogxz 4808 4 0,3 0,3 CD cord-015369-72cjogxz 4808 5 - - HYPH cord-015369-72cjogxz 4808 6 0,5 0,5 CD cord-015369-72cjogxz 4808 7 pro pro NN cord-015369-72cjogxz 4808 8 100.000 100.000 CD cord-015369-72cjogxz 4808 9 Einwohner Einwohner NNP cord-015369-72cjogxz 4808 10 pro pro JJ cord-015369-72cjogxz 4808 11 Jahr Jahr NNP cord-015369-72cjogxz 4808 12 . . . cord-015369-72cjogxz 4809 1 Während Während NNP cord-015369-72cjogxz 4809 2 die die VBP cord-015369-72cjogxz 4810 1 Ä ä NN cord-015369-72cjogxz 4810 2 tiologie tiologie NN cord-015369-72cjogxz 4810 3 primärer primärer NN cord-015369-72cjogxz 4810 4 Osteosarkome Osteosarkome NNP cord-015369-72cjogxz 4810 5 unklar unklar NNP cord-015369-72cjogxz 4811 1 ist ist NNP cord-015369-72cjogxz 4811 2 , , , cord-015369-72cjogxz 4811 3 können können NNP cord-015369-72cjogxz 4811 4 prädisponierende prädisponierende NNP cord-015369-72cjogxz 4812 1 Faktoren Faktoren NNP cord-015369-72cjogxz 4812 2 wie wie XX cord-015369-72cjogxz 4812 3 vorangegangene vorangegangene NNP cord-015369-72cjogxz 4813 1 Bestrahlung Bestrahlung NNP cord-015369-72cjogxz 4813 2 oder oder NNP cord-015369-72cjogxz 4814 1 Paget Paget NNP cord-015369-72cjogxz 4814 2 's 's POS cord-015369-72cjogxz 4814 3 disease disease NN cord-015369-72cjogxz 4814 4 sekundäre sekundäre NNP cord-015369-72cjogxz 4814 5 Osteosarkome Osteosarkome NNP cord-015369-72cjogxz 4814 6 ( ( -LRB- cord-015369-72cjogxz 4814 7 mit-)verursachen mit-)verursachen NNP cord-015369-72cjogxz 4814 8 . . . cord-015369-72cjogxz 4815 1 Das Das NNP cord-015369-72cjogxz 4815 2 Ziel Ziel NNP cord-015369-72cjogxz 4815 3 der der NN cord-015369-72cjogxz 4815 4 vorliegenden vorliegenden VBN cord-015369-72cjogxz 4815 5 Studie Studie NNP cord-015369-72cjogxz 4815 6 waren waren NNP cord-015369-72cjogxz 4815 7 die die VBP cord-015369-72cjogxz 4816 1 Berechnung Berechnung NNP cord-015369-72cjogxz 4816 2 der der NNP cord-015369-72cjogxz 4816 3 Inzidenz Inzidenz NNP cord-015369-72cjogxz 4816 4 für für IN cord-015369-72cjogxz 4816 5 Ö Ö NNP cord-015369-72cjogxz 4816 6 sterreich sterreich NN cord-015369-72cjogxz 4816 7 sowie sowie XX cord-015369-72cjogxz 4816 8 eine eine NNP cord-015369-72cjogxz 4817 1 Analyse Analyse NNP cord-015369-72cjogxz 4817 2 möglicher möglicher NNP cord-015369-72cjogxz 4817 3 Trends Trends NNP cord-015369-72cjogxz 4817 4 während während NNP cord-015369-72cjogxz 4817 5 der der NNP cord-015369-72cjogxz 4817 6 letzten letzten NNP cord-015369-72cjogxz 4817 7 20 20 CD cord-015369-72cjogxz 4817 8 Jahre Jahre NNP cord-015369-72cjogxz 4817 9 . . . cord-015369-72cjogxz 4818 1 Methodik Methodik NNP cord-015369-72cjogxz 4818 2 . . . cord-015369-72cjogxz 4819 1 Die Die NNP cord-015369-72cjogxz 4819 2 Autoren Autoren NNP cord-015369-72cjogxz 4819 3 führten führten NNP cord-015369-72cjogxz 4820 1 eine eine NNP cord-015369-72cjogxz 4820 2 retrospektive retrospektive NNP cord-015369-72cjogxz 4820 3 populationsbasierende populationsbasierende NNP cord-015369-72cjogxz 4820 4 Analyse Analyse NNP cord-015369-72cjogxz 4820 5 der der NNP cord-015369-72cjogxz 4820 6 Inzidenz Inzidenz NNP cord-015369-72cjogxz 4820 7 von von NNP cord-015369-72cjogxz 4820 8 Osteosarkomen Osteosarkomen NNP cord-015369-72cjogxz 4820 9 in in IN cord-015369-72cjogxz 4820 10 Ö Ö NNP cord-015369-72cjogxz 4820 11 sterreich sterreich NNP cord-015369-72cjogxz 4820 12 während während NNP cord-015369-72cjogxz 4820 13 der der NNP cord-015369-72cjogxz 4820 14 letzten letzten NNP cord-015369-72cjogxz 4821 1 21 21 CD cord-015369-72cjogxz 4821 2 Jahre Jahre NNP cord-015369-72cjogxz 4821 3 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4821 4 . . . cord-015369-72cjogxz 4822 1 Präoperatives Präoperatives NNP cord-015369-72cjogxz 4822 2 Serum Serum NNP cord-015369-72cjogxz 4822 3 - - HYPH cord-015369-72cjogxz 4822 4 CRP CRP NNP cord-015369-72cjogxz 4822 5 konnte konnte NN cord-015369-72cjogxz 4822 6 bereits bereits NNP cord-015369-72cjogxz 4822 7 für für NNP cord-015369-72cjogxz 4823 1 viele viele NNP cord-015369-72cjogxz 4823 2 Neoplasien Neoplasien NNP cord-015369-72cjogxz 4823 3 als als NN cord-015369-72cjogxz 4823 4 signifikanter signifikanter NN cord-015369-72cjogxz 4823 5 Prognosefaktor Prognosefaktor NNP cord-015369-72cjogxz 4823 6 nachgewiesen nachgewiesen NNP cord-015369-72cjogxz 4823 7 werden werden NNP cord-015369-72cjogxz 4823 8 . . . cord-015369-72cjogxz 4824 1 Für Für NNP cord-015369-72cjogxz 4824 2 das das NNP cord-015369-72cjogxz 4824 3 Osteosarkom Osteosarkom NNP cord-015369-72cjogxz 4824 4 konnte konnte NNP cord-015369-72cjogxz 4824 5 bislang bislang NNP cord-015369-72cjogxz 4824 6 kein kein NNP cord-015369-72cjogxz 4824 7 serologischer serologischer NNP cord-015369-72cjogxz 4825 1 Parameter parameter NN cord-015369-72cjogxz 4825 2 als als NN cord-015369-72cjogxz 4825 3 eindeutiger eindeutig JJR cord-015369-72cjogxz 4826 1 Prädiktor Prädiktor NNP cord-015369-72cjogxz 4826 2 identifiziert identifiziert NNP cord-015369-72cjogxz 4826 3 werden werden NNP cord-015369-72cjogxz 4826 4 . . . cord-015369-72cjogxz 4827 1 Ziel Ziel NNP cord-015369-72cjogxz 4827 2 dieser dieser NNP cord-015369-72cjogxz 4827 3 Studie Studie NNP cord-015369-72cjogxz 4827 4 war war NN cord-015369-72cjogxz 4827 5 es es NNP cord-015369-72cjogxz 4827 6 , , , cord-015369-72cjogxz 4827 7 die die VB cord-015369-72cjogxz 4827 8 prognostische prognostische NNP cord-015369-72cjogxz 4827 9 Bedeutung Bedeutung NNP cord-015369-72cjogxz 4827 10 des des FW cord-015369-72cjogxz 4827 11 präoperativen präoperativen NNP cord-015369-72cjogxz 4827 12 Serum Serum NNP cord-015369-72cjogxz 4827 13 - - HYPH cord-015369-72cjogxz 4827 14 CRP CRP NNP cord-015369-72cjogxz 4827 15 bei bei NNP cord-015369-72cjogxz 4827 16 Patienten Patienten NNP cord-015369-72cjogxz 4827 17 mit mit NNP cord-015369-72cjogxz 4827 18 Osteosarkom Osteosarkom NNP cord-015369-72cjogxz 4827 19 zu zu NNP cord-015369-72cjogxz 4827 20 untersuchen untersuchen NNP cord-015369-72cjogxz 4827 21 . . . cord-015369-72cjogxz 4828 1 Methodik Methodik NNP cord-015369-72cjogxz 4828 2 . . . cord-015369-72cjogxz 4829 1 Aus Aus NNP cord-015369-72cjogxz 4829 2 dem dem NNP cord-015369-72cjogxz 4829 3 prospektiven prospektiven NNP cord-015369-72cjogxz 4829 4 Wiener Wiener NNP cord-015369-72cjogxz 4829 5 Geschwulstregister Geschwulstregister NNP cord-015369-72cjogxz 4829 6 konnten konnten NNP cord-015369-72cjogxz 4829 7 87 87 CD cord-015369-72cjogxz 4830 1 an an DT cord-015369-72cjogxz 4830 2 einem einem NNP cord-015369-72cjogxz 4830 3 Osteosarkom Osteosarkom NNP cord-015369-72cjogxz 4830 4 erkrankte erkrankte NNP cord-015369-72cjogxz 4830 5 Patienten Patienten NNP cord-015369-72cjogxz 4830 6 ( ( -LRB- cord-015369-72cjogxz 4830 7 43 43 CD cord-015369-72cjogxz 4830 8 Frauen frauen NN cord-015369-72cjogxz 4830 9 und und IN cord-015369-72cjogxz 4831 1 44 44 CD cord-015369-72cjogxz 4831 2 Männer männer JJ cord-015369-72cjogxz 4831 3 mit mit XX cord-015369-72cjogxz 4831 4 einem einem NNP cord-015369-72cjogxz 4831 5 Durchschnittsalter Durchschnittsalter NNP cord-015369-72cjogxz 4831 6 von von NNP cord-015369-72cjogxz 4831 7 20,4 20,4 CD cord-015369-72cjogxz 4831 8 Jahren Jahren NNP cord-015369-72cjogxz 4831 9 ) ) -RRB- cord-015369-72cjogxz 4831 10 mit mit NNP cord-015369-72cjogxz 4831 11 vollständiger vollständiger NN cord-015369-72cjogxz 4831 12 Dokumentation Dokumentation NNP cord-015369-72cjogxz 4831 13 der der NNP cord-015369-72cjogxz 4832 1 prä prä UH cord-015369-72cjogxz 4832 2 - - HYPH cord-015369-72cjogxz 4832 3 und und NNP cord-015369-72cjogxz 4832 4 postoperativen postoperativen NNP cord-015369-72cjogxz 4832 5 CRP CRP NNP cord-015369-72cjogxz 4832 6 - - HYPH cord-015369-72cjogxz 4832 7 Werte Werte NNP cord-015369-72cjogxz 4832 8 und und IN cord-015369-72cjogxz 4832 9 nach nach NNP cord-015369-72cjogxz 4832 10 Ausschluß Ausschluß NNP cord-015369-72cjogxz 4833 1 einer einer NNP cord-015369-72cjogxz 4833 2 begleitenden begleitenden NNP cord-015369-72cjogxz 4833 3 Infektion Infektion NNP cord-015369-72cjogxz 4833 4 hinsichtlich hinsichtlich NN cord-015369-72cjogxz 4833 5 ihres ihre NNS cord-015369-72cjogxz 4833 6 Gesamtüberlebens Gesamtüberlebens NNP cord-015369-72cjogxz 4833 7 und und XX cord-015369-72cjogxz 4834 1 ihrer ihrer JJ cord-015369-72cjogxz 4834 2 Infektionsrate Infektionsrate NNP cord-015369-72cjogxz 4835 1 i i PRP cord-015369-72cjogxz 4836 1 m m NNP cord-015369-72cjogxz 4836 2 Rahmen Rahmen NNP cord-015369-72cjogxz 4836 3 einer einer NNP cord-015369-72cjogxz 4836 4 retrospektiven retrospektiven NNP cord-015369-72cjogxz 4837 1 Datenbankanalysenachuntersucht Datenbankanalysenachuntersucht NNP cord-015369-72cjogxz 4837 2 werden werden NNP cord-015369-72cjogxz 4837 3 . . . cord-015369-72cjogxz 4838 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4838 2 . . . cord-015369-72cjogxz 4839 1 Der Der NNP cord-015369-72cjogxz 4839 2 präoperative präoperative NNP cord-015369-72cjogxz 4839 3 CRP CRP NNP cord-015369-72cjogxz 4839 4 - - HYPH cord-015369-72cjogxz 4839 5 Wert Wert NNP cord-015369-72cjogxz 4839 6 betrug betrug NNP cord-015369-72cjogxz 4839 7 durchschnittlich durchschnittlich NNP cord-015369-72cjogxz 4840 1 0,73 0,73 CD cord-015369-72cjogxz 4841 1 mg mg NNP cord-015369-72cjogxz 4841 2 / / SYM cord-015369-72cjogxz 4841 3 dL dl NN cord-015369-72cjogxz 4842 1 ( ( -LRB- cord-015369-72cjogxz 4842 2 0,0 0,0 NFP cord-015369-72cjogxz 4843 1 bis bis NNP cord-015369-72cjogxz 4843 2 8,5 8,5 NNP cord-015369-72cjogxz 4843 3 ) ) -RRB- cord-015369-72cjogxz 4843 4 und und NNP cord-015369-72cjogxz 4843 5 korrelierte korrelierte NNP cord-015369-72cjogxz 4843 6 signifikant signifikant NNP cord-015369-72cjogxz 4843 7 mit mit NNP cord-015369-72cjogxz 4843 8 Gesamtüberleben Gesamtüberleben NNP cord-015369-72cjogxz 4843 9 , , , cord-015369-72cjogxz 4843 10 Operationsalter Operationsalter NNP cord-015369-72cjogxz 4843 11 und und IN cord-015369-72cjogxz 4843 12 histologischem histologischem NNP cord-015369-72cjogxz 4843 13 Subtyp Subtyp NNP cord-015369-72cjogxz 4843 14 , , , cord-015369-72cjogxz 4843 15 nicht nicht NNP cord-015369-72cjogxz 4843 16 jedoch jedoch NNP cord-015369-72cjogxz 4843 17 mit mit NNP cord-015369-72cjogxz 4843 18 Geschlecht Geschlecht NNP cord-015369-72cjogxz 4843 19 , , , cord-015369-72cjogxz 4843 20 Tumor tumor NN cord-015369-72cjogxz 4843 21 - - HYPH cord-015369-72cjogxz 4843 22 Grading grading NN cord-015369-72cjogxz 4843 23 , , , cord-015369-72cjogxz 4843 24 Ansprechrate Ansprechrate NNP cord-015369-72cjogxz 4843 25 auf auf NN cord-015369-72cjogxz 4843 26 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 4843 27 nach nach NNP cord-015369-72cjogxz 4843 28 Salzer Salzer NNP cord-015369-72cjogxz 4843 29 - - HYPH cord-015369-72cjogxz 4843 30 Kuntschik Kuntschik NNP cord-015369-72cjogxz 4843 31 , , , cord-015369-72cjogxz 4843 32 Metastasierungsrate Metastasierungsrate NNP cord-015369-72cjogxz 4843 33 und und IN cord-015369-72cjogxz 4843 34 postoperativer postoperativer NNP cord-015369-72cjogxz 4843 35 Infektionsrate Infektionsrate NNP cord-015369-72cjogxz 4843 36 . . . cord-015369-72cjogxz 4844 1 Patienten Patienten NNP cord-015369-72cjogxz 4844 2 mit mit VBP cord-015369-72cjogxz 4844 3 parostalem parostalem NNP cord-015369-72cjogxz 4845 1 Osteosarkom Osteosarkom NNP cord-015369-72cjogxz 4845 2 zeigten zeigten NNP cord-015369-72cjogxz 4845 3 signifikant signifikant NNP cord-015369-72cjogxz 4845 4 höhere höhere NNP cord-015369-72cjogxz 4845 5 CRP CRP NNP cord-015369-72cjogxz 4845 6 - - HYPH cord-015369-72cjogxz 4845 7 Werte Werte NNP cord-015369-72cjogxz 4845 8 als als NN cord-015369-72cjogxz 4845 9 in in IN cord-015369-72cjogxz 4845 10 Fällen Fällen NNP cord-015369-72cjogxz 4845 11 von von NNP cord-015369-72cjogxz 4845 12 klassischen klassischen NNP cord-015369-72cjogxz 4845 13 Osteosarkomen Osteosarkomen NNP cord-015369-72cjogxz 4845 14 . . . cord-015369-72cjogxz 4846 1 In in IN cord-015369-72cjogxz 4847 1 der der NNP cord-015369-72cjogxz 4847 2 multivariaten multivariaten NNP cord-015369-72cjogxz 4847 3 Analyse Analyse NNP cord-015369-72cjogxz 4847 4 hatten hatten NNP cord-015369-72cjogxz 4848 1 sowohl sowohl NNP cord-015369-72cjogxz 4848 2 Alter Alter NNP cord-015369-72cjogxz 4848 3 als als NNP cord-015369-72cjogxz 4848 4 auch auch NNP cord-015369-72cjogxz 4848 5 der der NNP cord-015369-72cjogxz 4848 6 präoperative präoperative NNP cord-015369-72cjogxz 4849 1 CRP CRP NNP cord-015369-72cjogxz 4849 2 - - HYPH cord-015369-72cjogxz 4849 3 Wert Wert NNP cord-015369-72cjogxz 4849 4 einen einen JJ cord-015369-72cjogxz 4849 5 signifikanten signifikanten NN cord-015369-72cjogxz 4849 6 Einfluß Einfluß NNP cord-015369-72cjogxz 4849 7 auf auf NNP cord-015369-72cjogxz 4849 8 das das NNP cord-015369-72cjogxz 4849 9 Gesamtü Gesamtü NNP cord-015369-72cjogxz 4849 10 berleben berleben NN cord-015369-72cjogxz 4849 11 . . . cord-015369-72cjogxz 4850 1 Patienten Patienten NNP cord-015369-72cjogxz 4850 2 mit mit XX cord-015369-72cjogxz 4850 3 präoperativen präoperativen VBN cord-015369-72cjogxz 4851 1 CRP CRP NNP cord-015369-72cjogxz 4851 2 - - HYPH cord-015369-72cjogxz 4851 3 Werten Werten NNP cord-015369-72cjogxz 4851 4 < < XX cord-015369-72cjogxz 4851 5 1 1 CD cord-015369-72cjogxz 4852 1 mg mg NNP cord-015369-72cjogxz 4852 2 / / SYM cord-015369-72cjogxz 4852 3 dL dl NN cord-015369-72cjogxz 4852 4 zeigten zeigten NNP cord-015369-72cjogxz 4853 1 ein ein NNP cord-015369-72cjogxz 4853 2 5-Jahresgesamtü 5-Jahresgesamtü NNP cord-015369-72cjogxz 4853 3 berleben berleben NN cord-015369-72cjogxz 4853 4 von von NNP cord-015369-72cjogxz 4853 5 70 70 CD cord-015369-72cjogxz 4853 6 % % NN cord-015369-72cjogxz 4853 7 gegenü gegenü NN cord-015369-72cjogxz 4853 8 ber ber NNP cord-015369-72cjogxz 4854 1 43 43 CD cord-015369-72cjogxz 4854 2 % % NN cord-015369-72cjogxz 4854 3 fü fü IN cord-015369-72cjogxz 4855 1 r r LS cord-015369-72cjogxz 4855 2 Patienten Patienten NNP cord-015369-72cjogxz 4855 3 mit mit NNP cord-015369-72cjogxz 4855 4 CRP CRP NNP cord-015369-72cjogxz 4855 5 - - HYPH cord-015369-72cjogxz 4855 6 Werten Werten NNP cord-015369-72cjogxz 4856 1 > > XX cord-015369-72cjogxz 4857 1 1 1 CD cord-015369-72cjogxz 4857 2 mg/ mg/ NN cord-015369-72cjogxz 4858 1 dL. dL. NNP cord-015369-72cjogxz 4858 2 Präoperatives Präoperatives NNP cord-015369-72cjogxz 4859 1 Serum serum NN cord-015369-72cjogxz 4859 2 - - HYPH cord-015369-72cjogxz 4859 3 CRP CRP NNP cord-015369-72cjogxz 4859 4 war war NN cord-015369-72cjogxz 4859 5 sowohl sowohl NNP cord-015369-72cjogxz 4859 6 ohne ohne NNP cord-015369-72cjogxz 4859 7 als als NNP cord-015369-72cjogxz 4859 8 auch auch NNP cord-015369-72cjogxz 4859 9 mit mit NNP cord-015369-72cjogxz 4859 10 Landmark Landmark NNP cord-015369-72cjogxz 4859 11 - - HYPH cord-015369-72cjogxz 4859 12 Analyse Analyse NNP cord-015369-72cjogxz 4859 13 kein kein NNP cord-015369-72cjogxz 4859 14 Prognosefaktor Prognosefaktor NNP cord-015369-72cjogxz 4859 15 fü fü IN cord-015369-72cjogxz 4860 1 r r LS cord-015369-72cjogxz 4860 2 Protheseninfektion Protheseninfektion NNP cord-015369-72cjogxz 4860 3 bei bei NNP cord-015369-72cjogxz 4860 4 60 60 CD cord-015369-72cjogxz 4860 5 Patienten Patienten NNP cord-015369-72cjogxz 4860 6 , , , cord-015369-72cjogxz 4860 7 die die VBP cord-015369-72cjogxz 4860 8 mit mit NNP cord-015369-72cjogxz 4860 9 Tumorporthesen Tumorporthesen NNP cord-015369-72cjogxz 4860 10 versorgt versorgt NN cord-015369-72cjogxz 4860 11 waren waren NNP cord-015369-72cjogxz 4860 12 . . . cord-015369-72cjogxz 4861 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4861 2 . . . cord-015369-72cjogxz 4862 1 Präoperatives Präoperatives NNP cord-015369-72cjogxz 4862 2 Serum Serum NNP cord-015369-72cjogxz 4862 3 - - HYPH cord-015369-72cjogxz 4862 4 CRP crp NN cord-015369-72cjogxz 4863 1 ist ist NNP cord-015369-72cjogxz 4863 2 ein ein NNP cord-015369-72cjogxz 4863 3 unabhängiger unabhängiger NNP cord-015369-72cjogxz 4863 4 Prädiktor Prädiktor NNP cord-015369-72cjogxz 4863 5 für für IN cord-015369-72cjogxz 4863 6 das das NNP cord-015369-72cjogxz 4863 7 Gesamtüberleben Gesamtüberleben NNP cord-015369-72cjogxz 4863 8 bei bei NNP cord-015369-72cjogxz 4863 9 Patienten Patienten NNP cord-015369-72cjogxz 4863 10 mit mit NNP cord-015369-72cjogxz 4863 11 Osteosarkom Osteosarkom NNP cord-015369-72cjogxz 4863 12 . . . cord-015369-72cjogxz 4864 1 Inwiefern Inwiefern NNP cord-015369-72cjogxz 4864 2 es es XX cord-015369-72cjogxz 4864 3 in in IN cord-015369-72cjogxz 4864 4 diesem diesem JJ cord-015369-72cjogxz 4864 5 Zusammenhang Zusammenhang NNP cord-015369-72cjogxz 4864 6 auch auch NNP cord-015369-72cjogxz 4864 7 einen einen NNP cord-015369-72cjogxz 4864 8 Prädiktor Prädiktor NNP cord-015369-72cjogxz 4864 9 für für IN cord-015369-72cjogxz 4864 10 das das NNP cord-015369-72cjogxz 4864 11 Chemotherapieansprechen Chemotherapieansprechen NNP cord-015369-72cjogxz 4864 12 darstellt darstellt NNP cord-015369-72cjogxz 4865 1 und und NNP cord-015369-72cjogxz 4866 1 welche welche NNP cord-015369-72cjogxz 4866 2 prognostische prognostische NNP cord-015369-72cjogxz 4866 3 Rolle Rolle NNP cord-015369-72cjogxz 4866 4 dem dem NNP cord-015369-72cjogxz 4866 5 Protheseninfekt Protheseninfekt NNP cord-015369-72cjogxz 4866 6 zukommt zukommt NNP cord-015369-72cjogxz 4866 7 , , , cord-015369-72cjogxz 4866 8 erfordert erfordert NNP cord-015369-72cjogxz 4866 9 aufgrund aufgrund NNP cord-015369-72cjogxz 4866 10 der der NNP cord-015369-72cjogxz 4866 11 geringen geringen NNP cord-015369-72cjogxz 4866 12 Inzidenz Inzidenz NNP cord-015369-72cjogxz 4867 1 größere größere NNP cord-015369-72cjogxz 4867 2 Datenbankanalysen Datenbankanalysen NNP cord-015369-72cjogxz 4867 3 i -PRON- PRP cord-015369-72cjogxz 4867 4 m be VBP cord-015369-72cjogxz 4867 5 Rahmen Rahmen NNP cord-015369-72cjogxz 4867 6 von von NNP cord-015369-72cjogxz 4867 7 Multicenter Multicenter NNP cord-015369-72cjogxz 4867 8 - - HYPH cord-015369-72cjogxz 4867 9 Studien Studien NNP cord-015369-72cjogxz 4867 10 . . . cord-015369-72cjogxz 4868 1 Methodik Methodik NNP cord-015369-72cjogxz 4868 2 . . . cord-015369-72cjogxz 4869 1 Alle Alle NNP cord-015369-72cjogxz 4870 1 gemeldeten gemeldeten NNP cord-015369-72cjogxz 4871 1 Fälle Fälle NNP cord-015369-72cjogxz 4871 2 von von NNP cord-015369-72cjogxz 4871 3 Weichteilsarkomen Weichteilsarkomen NNP cord-015369-72cjogxz 4871 4 ( ( -LRB- cord-015369-72cjogxz 4871 5 entsprechend entsprechend NNP cord-015369-72cjogxz 4871 6 der der NNP cord-015369-72cjogxz 4871 7 Standard Standard NNP cord-015369-72cjogxz 4871 8 Intnernational Intnernational NNP cord-015369-72cjogxz 4871 9 Classification Classification NNP cord-015369-72cjogxz 4871 10 of of IN cord-015369-72cjogxz 4871 11 Diseases Diseases NNPS cord-015369-72cjogxz 4871 12 for for IN cord-015369-72cjogxz 4871 13 Oncology Oncology NNP cord-015369-72cjogxz 4871 14 , , , cord-015369-72cjogxz 4871 15 ICD ICD NNP cord-015369-72cjogxz 4871 16 - - HYPH cord-015369-72cjogxz 4871 17 O-3 O-3 NNP cord-015369-72cjogxz 4871 18 ) ) -RRB- cord-015369-72cjogxz 4872 1 aus aus NNP cord-015369-72cjogxz 4872 2 dem dem NNP cord-015369-72cjogxz 4872 3 Krebsregister Krebsregister NNP cord-015369-72cjogxz 4872 4 der der NNP cord-015369-72cjogxz 4872 5 Statistik Statistik NNP cord-015369-72cjogxz 4872 6 Austria Austria NNP cord-015369-72cjogxz 4872 7 wurden wurden VBD cord-015369-72cjogxz 4872 8 in in IN cord-015369-72cjogxz 4872 9 unseren unseren NNP cord-015369-72cjogxz 4872 10 Datensatz Datensatz NNP cord-015369-72cjogxz 4872 11 aufgenommen aufgenommen VBP cord-015369-72cjogxz 4872 12 und und XX cord-015369-72cjogxz 4873 1 die die VB cord-015369-72cjogxz 4873 2 altersstandardisierte altersstandardisierte NNP cord-015369-72cjogxz 4873 3 Inzidenz Inzidenz NNP cord-015369-72cjogxz 4873 4 , , , cord-015369-72cjogxz 4873 5 Alters alter VBZ cord-015369-72cjogxz 4873 6 - - : cord-015369-72cjogxz 4873 7 und und NNP cord-015369-72cjogxz 4873 8 Geschlechtsverteilung Geschlechtsverteilung NNP cord-015369-72cjogxz 4873 9 sowie sowie CD cord-015369-72cjogxz 4873 10 geographische geographische NN cord-015369-72cjogxz 4873 11 Unterschiede Unterschiede NNP cord-015369-72cjogxz 4873 12 analysiert analysiert NN cord-015369-72cjogxz 4873 13 . . . cord-015369-72cjogxz 4874 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4874 2 . . . cord-015369-72cjogxz 4875 1 Insgesamt Insgesamt NNP cord-015369-72cjogxz 4875 2 wurden wurden VBD cord-015369-72cjogxz 4875 3 5333 5333 CD cord-015369-72cjogxz 4875 4 Fälle Fälle NNP cord-015369-72cjogxz 4875 5 registriert registriert NNP cord-015369-72cjogxz 4875 6 , , , cord-015369-72cjogxz 4875 7 mit mit NNP cord-015369-72cjogxz 4875 8 einem einem NNP cord-015369-72cjogxz 4875 9 Verhältnis Verhältnis NNP cord-015369-72cjogxz 4875 10 Männer Männer NNP cord-015369-72cjogxz 4875 11 / / SYM cord-015369-72cjogxz 4875 12 Frauen Frauen NNP cord-015369-72cjogxz 4875 13 von von NNP cord-015369-72cjogxz 4875 14 0,8 0,8 CD cord-015369-72cjogxz 4875 15 . . . cord-015369-72cjogxz 4876 1 Die die VB cord-015369-72cjogxz 4876 2 häufigsten häufigsten NNP cord-015369-72cjogxz 4876 3 Entitäten Entitäten NNP cord-015369-72cjogxz 4876 4 waren waren VBD cord-015369-72cjogxz 4876 5 : : : cord-015369-72cjogxz 4876 6 Sarkom Sarkom NNP cord-015369-72cjogxz 4876 7 ( ( -LRB- cord-015369-72cjogxz 4876 8 NOS NOS NNP cord-015369-72cjogxz 4876 9 ) ) -RRB- cord-015369-72cjogxz 4876 10 ( ( -LRB- cord-015369-72cjogxz 4876 11 36 36 CD cord-015369-72cjogxz 4876 12 % % NN cord-015369-72cjogxz 4876 13 ) ) -RRB- cord-015369-72cjogxz 4876 14 , , , cord-015369-72cjogxz 4876 15 Leiomyosarkom Leiomyosarkom NNP cord-015369-72cjogxz 4876 16 ( ( -LRB- cord-015369-72cjogxz 4876 17 24 24 CD cord-015369-72cjogxz 4876 18 % % NN cord-015369-72cjogxz 4876 19 ) ) -RRB- cord-015369-72cjogxz 4876 20 , , , cord-015369-72cjogxz 4876 21 Liposarkom Liposarkom NNP cord-015369-72cjogxz 4876 22 ( ( -LRB- cord-015369-72cjogxz 4876 23 12 12 CD cord-015369-72cjogxz 4876 24 % % NN cord-015369-72cjogxz 4876 25 ) ) -RRB- cord-015369-72cjogxz 4877 1 , , , cord-015369-72cjogxz 4877 2 Malignes Malignes NNP cord-015369-72cjogxz 4877 3 Fibröses Fibröses NNP cord-015369-72cjogxz 4877 4 Histiozytom Histiozytom NNP cord-015369-72cjogxz 4877 5 ( ( -LRB- cord-015369-72cjogxz 4877 6 MFH MFH NNP cord-015369-72cjogxz 4877 7 , , , cord-015369-72cjogxz 4877 8 9 9 CD cord-015369-72cjogxz 4877 9 % % NN cord-015369-72cjogxz 4877 10 ) ) -RRB- cord-015369-72cjogxz 4877 11 und und RB cord-015369-72cjogxz 4878 1 Fibrosarkom Fibrosarkom NNP cord-015369-72cjogxz 4878 2 ( ( -LRB- cord-015369-72cjogxz 4878 3 5 5 CD cord-015369-72cjogxz 4878 4 % % NN cord-015369-72cjogxz 4878 5 ) ) -RRB- cord-015369-72cjogxz 4878 6 . . . cord-015369-72cjogxz 4879 1 Die die VB cord-015369-72cjogxz 4879 2 durchschnittliche durchschnittliche NN cord-015369-72cjogxz 4879 3 altersstandardisierte altersstandardisierte NNS cord-015369-72cjogxz 4879 4 Inzidenzrate Inzidenzrate NNP cord-015369-72cjogxz 4879 5 lag lag VBP cord-015369-72cjogxz 4879 6 bei bei NNP cord-015369-72cjogxz 4879 7 2,4/100.000 2,4/100.000 CD cord-015369-72cjogxz 4879 8 / / SYM cord-015369-72cjogxz 4879 9 Jahr Jahr NNP cord-015369-72cjogxz 4879 10 . . . cord-015369-72cjogxz 4880 1 Die die VB cord-015369-72cjogxz 4880 2 Analyse Analyse NNP cord-015369-72cjogxz 4880 3 der der NNP cord-015369-72cjogxz 4880 4 jährlichen jährlichen NNP cord-015369-72cjogxz 4880 5 sowie sowie NNP cord-015369-72cjogxz 4880 6 über über NNP cord-015369-72cjogxz 4880 7 drei drei NNP cord-015369-72cjogxz 4880 8 Jahre Jahre NNP cord-015369-72cjogxz 4880 9 gemittelten gemittelten NNP cord-015369-72cjogxz 4880 10 Inzidenzen Inzidenzen NNP cord-015369-72cjogxz 4880 11 ergab ergab NN cord-015369-72cjogxz 4880 12 keinen keinen NNP cord-015369-72cjogxz 4880 13 Anstieg Anstieg NNP cord-015369-72cjogxz 4880 14 der der NNP cord-015369-72cjogxz 4880 15 Inzidenzraten Inzidenzraten NNP cord-015369-72cjogxz 4880 16 ( ( -LRB- cord-015369-72cjogxz 4880 17 jährlicher jährlicher NNP cord-015369-72cjogxz 4880 18 Gradient Gradient NNP cord-015369-72cjogxz 4880 19 : : : cord-015369-72cjogxz 4880 20 À0,0025 À0,0025 NNP cord-015369-72cjogxz 4880 21 ) ) -RRB- cord-015369-72cjogxz 4880 22 . . . cord-015369-72cjogxz 4881 1 I -PRON- PRP cord-015369-72cjogxz 4881 2 m be VBP cord-015369-72cjogxz 4881 3 Bundesländervergleich Bundesländervergleich NNP cord-015369-72cjogxz 4881 4 zeigten zeigten XX cord-015369-72cjogxz 4881 5 sich sich NNP cord-015369-72cjogxz 4881 6 regionale regionale NNP cord-015369-72cjogxz 4881 7 Unterschiede Unterschiede NNP cord-015369-72cjogxz 4881 8 , , , cord-015369-72cjogxz 4881 9 mit mit NNP cord-015369-72cjogxz 4881 10 der der NNP cord-015369-72cjogxz 4881 11 höchsten höchsten NNP cord-015369-72cjogxz 4881 12 Inzidenzrate Inzidenzrate NNP cord-015369-72cjogxz 4881 13 in in IN cord-015369-72cjogxz 4881 14 Tirol Tirol NNP cord-015369-72cjogxz 4882 1 ( ( -LRB- cord-015369-72cjogxz 4882 2 3,2/100.000 3,2/100.000 CD cord-015369-72cjogxz 4882 3 / / SYM cord-015369-72cjogxz 4882 4 Jahr Jahr NNP cord-015369-72cjogxz 4882 5 ) ) -RRB- cord-015369-72cjogxz 4882 6 . . . cord-015369-72cjogxz 4883 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4883 2 Musculoskeletal musculoskeletal JJ cord-015369-72cjogxz 4883 3 tumours tumour NNS cord-015369-72cjogxz 4883 4 are be VBP cord-015369-72cjogxz 4883 5 rare rare JJ cord-015369-72cjogxz 4883 6 with with IN cord-015369-72cjogxz 4883 7 an an DT cord-015369-72cjogxz 4883 8 incidence incidence NN cord-015369-72cjogxz 4883 9 of of IN cord-015369-72cjogxz 4883 10 3 3 CD cord-015369-72cjogxz 4883 11 - - SYM cord-015369-72cjogxz 4883 12 4 4 CD cord-015369-72cjogxz 4883 13 patients patient NNS cord-015369-72cjogxz 4883 14 / / SYM cord-015369-72cjogxz 4883 15 year/1 year/1 NNP cord-015369-72cjogxz 4883 16 million million CD cord-015369-72cjogxz 4883 17 . . . cord-015369-72cjogxz 4884 1 Before before IN cord-015369-72cjogxz 4884 2 any any DT cord-015369-72cjogxz 4884 3 imaging imaging NN cord-015369-72cjogxz 4884 4 procedure procedure NN cord-015369-72cjogxz 4884 5 clinical clinical JJ cord-015369-72cjogxz 4884 6 assessment assessment NN cord-015369-72cjogxz 4884 7 has have VBZ cord-015369-72cjogxz 4884 8 to to TO cord-015369-72cjogxz 4884 9 be be VB cord-015369-72cjogxz 4884 10 carried carry VBN cord-015369-72cjogxz 4884 11 out out RP cord-015369-72cjogxz 4884 12 . . . cord-015369-72cjogxz 4885 1 The the DT cord-015369-72cjogxz 4885 2 first first JJ cord-015369-72cjogxz 4885 3 pitfall pitfall NN cord-015369-72cjogxz 4885 4 is be VBZ cord-015369-72cjogxz 4885 5 a a DT cord-015369-72cjogxz 4885 6 delayed delay VBN cord-015369-72cjogxz 4885 7 diagnosis diagnosis NN cord-015369-72cjogxz 4885 8 . . . cord-015369-72cjogxz 4886 1 Bone bone NN cord-015369-72cjogxz 4886 2 tumours tumour NNS cord-015369-72cjogxz 4886 3 are be VBP cord-015369-72cjogxz 4886 4 often often RB cord-015369-72cjogxz 4886 5 accompanied accompany VBN cord-015369-72cjogxz 4886 6 with with IN cord-015369-72cjogxz 4886 7 early early JJ cord-015369-72cjogxz 4886 8 pain pain NN cord-015369-72cjogxz 4886 9 and and CC cord-015369-72cjogxz 4886 10 swelling swelling NN cord-015369-72cjogxz 4886 11 and and CC cord-015369-72cjogxz 4886 12 these these DT cord-015369-72cjogxz 4886 13 symptoms symptom NNS cord-015369-72cjogxz 4886 14 lead lead VBP cord-015369-72cjogxz 4886 15 the the DT cord-015369-72cjogxz 4886 16 patient patient NN cord-015369-72cjogxz 4886 17 and and CC cord-015369-72cjogxz 4886 18 the the DT cord-015369-72cjogxz 4886 19 physician physician NN cord-015369-72cjogxz 4886 20 to to TO cord-015369-72cjogxz 4886 21 perform perform VB cord-015369-72cjogxz 4886 22 further further JJ cord-015369-72cjogxz 4886 23 investigation investigation NN cord-015369-72cjogxz 4886 24 . . . cord-015369-72cjogxz 4887 1 For for IN cord-015369-72cjogxz 4887 2 soft soft JJ cord-015369-72cjogxz 4887 3 tissue tissue NN cord-015369-72cjogxz 4887 4 sarcomas sarcoma NNS cord-015369-72cjogxz 4887 5 , , , cord-015369-72cjogxz 4887 6 especially especially RB cord-015369-72cjogxz 4887 7 for for IN cord-015369-72cjogxz 4887 8 the the DT cord-015369-72cjogxz 4887 9 retroperitoneal retroperitoneal JJ cord-015369-72cjogxz 4887 10 localisation localisation NN cord-015369-72cjogxz 4887 11 , , , cord-015369-72cjogxz 4887 12 first first JJ cord-015369-72cjogxz 4887 13 symptoms symptom NNS cord-015369-72cjogxz 4887 14 lack lack VBP cord-015369-72cjogxz 4887 15 or or CC cord-015369-72cjogxz 4887 16 are be VBP cord-015369-72cjogxz 4887 17 noticed notice VBN cord-015369-72cjogxz 4887 18 after after IN cord-015369-72cjogxz 4887 19 the the DT cord-015369-72cjogxz 4887 20 tumour tumour NN cord-015369-72cjogxz 4887 21 has have VBZ cord-015369-72cjogxz 4887 22 achieved achieve VBN cord-015369-72cjogxz 4887 23 an an DT cord-015369-72cjogxz 4887 24 important important JJ cord-015369-72cjogxz 4887 25 extension extension NN cord-015369-72cjogxz 4887 26 . . . cord-015369-72cjogxz 4888 1 Another another DT cord-015369-72cjogxz 4888 2 important important JJ cord-015369-72cjogxz 4888 3 pitfall pitfall NN cord-015369-72cjogxz 4888 4 is be VBZ cord-015369-72cjogxz 4888 5 the the DT cord-015369-72cjogxz 4888 6 diagnosis diagnosis NN cord-015369-72cjogxz 4888 7 ' ' '' cord-015369-72cjogxz 4888 8 ' ' `` cord-015369-72cjogxz 4888 9 haematoma haematoma NN cord-015369-72cjogxz 4888 10 ' ' '' cord-015369-72cjogxz 4888 11 ' ' '' cord-015369-72cjogxz 4888 12 . . . cord-015369-72cjogxz 4889 1 Every every DT cord-015369-72cjogxz 4889 2 tumour tumour NN cord-015369-72cjogxz 4889 3 has have VBZ cord-015369-72cjogxz 4889 4 to to TO cord-015369-72cjogxz 4889 5 be be VB cord-015369-72cjogxz 4889 6 considered consider VBN cord-015369-72cjogxz 4889 7 as as RB cord-015369-72cjogxz 4889 8 malign malign JJ cord-015369-72cjogxz 4889 9 until until IN cord-015369-72cjogxz 4889 10 malignancy malignancy NN cord-015369-72cjogxz 4889 11 is be VBZ cord-015369-72cjogxz 4889 12 excluded exclude VBN cord-015369-72cjogxz 4889 13 in in IN cord-015369-72cjogxz 4889 14 further further JJ cord-015369-72cjogxz 4889 15 imaging imaging NN cord-015369-72cjogxz 4889 16 investigation investigation NN cord-015369-72cjogxz 4889 17 . . . cord-015369-72cjogxz 4890 1 There there EX cord-015369-72cjogxz 4890 2 is be VBZ cord-015369-72cjogxz 4890 3 a a DT cord-015369-72cjogxz 4890 4 number number NN cord-015369-72cjogxz 4890 5 of of IN cord-015369-72cjogxz 4890 6 frequently frequently RB cord-015369-72cjogxz 4890 7 encountered encounter VBN cord-015369-72cjogxz 4890 8 and and CC cord-015369-72cjogxz 4890 9 management management NN cord-015369-72cjogxz 4890 10 pitfalls pitfall NNS cord-015369-72cjogxz 4890 11 in in IN cord-015369-72cjogxz 4890 12 the the DT cord-015369-72cjogxz 4890 13 diagnosis diagnosis NN cord-015369-72cjogxz 4890 14 of of IN cord-015369-72cjogxz 4890 15 musculoskeletal musculoskeletal JJ cord-015369-72cjogxz 4890 16 tumours tumour NNS cord-015369-72cjogxz 4890 17 and and CC cord-015369-72cjogxz 4890 18 limits limit NNS cord-015369-72cjogxz 4890 19 in in IN cord-015369-72cjogxz 4890 20 the the DT cord-015369-72cjogxz 4890 21 diagnostic diagnostic JJ cord-015369-72cjogxz 4890 22 possibilities possibility NNS cord-015369-72cjogxz 4890 23 even even RB cord-015369-72cjogxz 4890 24 for for IN cord-015369-72cjogxz 4890 25 an an DT cord-015369-72cjogxz 4890 26 experienced experienced JJ cord-015369-72cjogxz 4890 27 physicians physician NNS cord-015369-72cjogxz 4890 28 . . . cord-015369-72cjogxz 4891 1 Interpretation interpretation NN cord-015369-72cjogxz 4891 2 of of IN cord-015369-72cjogxz 4891 3 an an DT cord-015369-72cjogxz 4891 4 MRI MRI NNP cord-015369-72cjogxz 4891 5 of of IN cord-015369-72cjogxz 4891 6 a a DT cord-015369-72cjogxz 4891 7 suspected suspect VBN cord-015369-72cjogxz 4891 8 neoplasm neoplasm NN cord-015369-72cjogxz 4891 9 can can MD cord-015369-72cjogxz 4891 10 be be VB cord-015369-72cjogxz 4891 11 extremely extremely RB cord-015369-72cjogxz 4891 12 difficult difficult JJ cord-015369-72cjogxz 4891 13 . . . cord-015369-72cjogxz 4892 1 This this DT cord-015369-72cjogxz 4892 2 reveals reveal VBZ cord-015369-72cjogxz 4892 3 how how WRB cord-015369-72cjogxz 4892 4 important important JJ cord-015369-72cjogxz 4892 5 an an DT cord-015369-72cjogxz 4892 6 interdisciplinary interdisciplinary JJ cord-015369-72cjogxz 4892 7 approach approach NN cord-015369-72cjogxz 4892 8 , , , cord-015369-72cjogxz 4892 9 for for IN cord-015369-72cjogxz 4892 10 the the DT cord-015369-72cjogxz 4892 11 example example NN cord-015369-72cjogxz 4892 12 the the DT cord-015369-72cjogxz 4892 13 tumour tumour NN cord-015369-72cjogxz 4892 14 board board NN cord-015369-72cjogxz 4892 15 , , , cord-015369-72cjogxz 4892 16 in in IN cord-015369-72cjogxz 4892 17 the the DT cord-015369-72cjogxz 4892 18 diagnosis diagnosis NN cord-015369-72cjogxz 4892 19 is be VBZ cord-015369-72cjogxz 4892 20 . . . cord-015369-72cjogxz 4893 1 The the DT cord-015369-72cjogxz 4893 2 final final JJ cord-015369-72cjogxz 4893 3 diagnostic diagnostic JJ cord-015369-72cjogxz 4893 4 skill skill NN cord-015369-72cjogxz 4893 5 is be VBZ cord-015369-72cjogxz 4893 6 the the DT cord-015369-72cjogxz 4893 7 adequate adequate JJ cord-015369-72cjogxz 4893 8 biopsy biopsy NN cord-015369-72cjogxz 4893 9 . . . cord-015369-72cjogxz 4894 1 Biopsy Biopsy NNP cord-015369-72cjogxz 4894 2 is be VBZ cord-015369-72cjogxz 4894 3 the the DT cord-015369-72cjogxz 4894 4 key key JJ cord-015369-72cjogxz 4894 5 step step NN cord-015369-72cjogxz 4894 6 in in IN cord-015369-72cjogxz 4894 7 the the DT cord-015369-72cjogxz 4894 8 diagnosis diagnosis NN cord-015369-72cjogxz 4894 9 of of IN cord-015369-72cjogxz 4894 10 musculoskeletal musculoskeletal JJ cord-015369-72cjogxz 4894 11 tumours tumour NNS cord-015369-72cjogxz 4894 12 . . . cord-015369-72cjogxz 4895 1 Possible possible JJ cord-015369-72cjogxz 4895 2 pitfalls pitfall NNS cord-015369-72cjogxz 4895 3 are be VBP cord-015369-72cjogxz 4895 4 : : : cord-015369-72cjogxz 4895 5 the the DT cord-015369-72cjogxz 4895 6 suspected suspect VBN cord-015369-72cjogxz 4895 7 lesion lesion NN cord-015369-72cjogxz 4895 8 missed miss VBN cord-015369-72cjogxz 4895 9 , , , cord-015369-72cjogxz 4895 10 the the DT cord-015369-72cjogxz 4895 11 biopsy biopsy NN cord-015369-72cjogxz 4895 12 is be VBZ cord-015369-72cjogxz 4895 13 done do VBN cord-015369-72cjogxz 4895 14 of of IN cord-015369-72cjogxz 4895 15 the the DT cord-015369-72cjogxz 4895 16 reactive reactive JJ cord-015369-72cjogxz 4895 17 zone zone NN cord-015369-72cjogxz 4895 18 of of IN cord-015369-72cjogxz 4895 19 the the DT cord-015369-72cjogxz 4895 20 tumour tumour NN cord-015369-72cjogxz 4895 21 is be VBZ cord-015369-72cjogxz 4895 22 and and CC cord-015369-72cjogxz 4895 23 the the DT cord-015369-72cjogxz 4895 24 sampling sampling NN cord-015369-72cjogxz 4895 25 error error NN cord-015369-72cjogxz 4895 26 . . . cord-015369-72cjogxz 4896 1 Inadequate inadequate JJ cord-015369-72cjogxz 4896 2 approach approach NN cord-015369-72cjogxz 4896 3 and and CC cord-015369-72cjogxz 4896 4 surgical surgical JJ cord-015369-72cjogxz 4896 5 technique technique NN cord-015369-72cjogxz 4896 6 of of IN cord-015369-72cjogxz 4896 7 the the DT cord-015369-72cjogxz 4896 8 biopsy biopsy NN cord-015369-72cjogxz 4896 9 can can MD cord-015369-72cjogxz 4896 10 complicate complicate VB cord-015369-72cjogxz 4896 11 the the DT cord-015369-72cjogxz 4896 12 tumour tumour NN cord-015369-72cjogxz 4896 13 resection resection NN cord-015369-72cjogxz 4896 14 or or CC cord-015369-72cjogxz 4896 15 even even RB cord-015369-72cjogxz 4896 16 make make VB cord-015369-72cjogxz 4896 17 a a DT cord-015369-72cjogxz 4896 18 limb limb NN cord-015369-72cjogxz 4896 19 spearing spear VBG cord-015369-72cjogxz 4896 20 procedure procedure NN cord-015369-72cjogxz 4896 21 impossible impossible JJ cord-015369-72cjogxz 4896 22 and and CC cord-015369-72cjogxz 4896 23 necessitate necessitate VBP cord-015369-72cjogxz 4896 24 amputation amputation NN cord-015369-72cjogxz 4896 25 to to TO cord-015369-72cjogxz 4896 26 obtain obtain VB cord-015369-72cjogxz 4896 27 adequate adequate JJ cord-015369-72cjogxz 4896 28 resection resection NN cord-015369-72cjogxz 4896 29 margins margin NNS cord-015369-72cjogxz 4896 30 . . . cord-015369-72cjogxz 4897 1 This this DT cord-015369-72cjogxz 4897 2 workout workout NN cord-015369-72cjogxz 4897 3 reviews review VBZ cord-015369-72cjogxz 4897 4 various various JJ cord-015369-72cjogxz 4897 5 errors error NNS cord-015369-72cjogxz 4897 6 in in IN cord-015369-72cjogxz 4897 7 the the DT cord-015369-72cjogxz 4897 8 diagnosis diagnosis NN cord-015369-72cjogxz 4897 9 of of IN cord-015369-72cjogxz 4897 10 bone bone NN cord-015369-72cjogxz 4897 11 tumours tumour NNS cord-015369-72cjogxz 4897 12 , , , cord-015369-72cjogxz 4897 13 soft soft JJ cord-015369-72cjogxz 4897 14 tissue tissue NN cord-015369-72cjogxz 4897 15 sarcomas sarcoma NNS cord-015369-72cjogxz 4897 16 and and CC cord-015369-72cjogxz 4897 17 metastasis metastasis NN cord-015369-72cjogxz 4897 18 and and CC cord-015369-72cjogxz 4897 19 points point VBZ cord-015369-72cjogxz 4897 20 out out RP cord-015369-72cjogxz 4897 21 how how WRB cord-015369-72cjogxz 4897 22 important important JJ cord-015369-72cjogxz 4897 23 biopsy biopsy NN cord-015369-72cjogxz 4897 24 is be VBZ cord-015369-72cjogxz 4897 25 . . . cord-015369-72cjogxz 4898 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4898 2 . . . cord-015369-72cjogxz 4899 1 Das Das NNP cord-015369-72cjogxz 4899 2 Ö Ö NNP cord-015369-72cjogxz 4899 3 sophaguskarzinom sophaguskarzinom NNP cord-015369-72cjogxz 4899 4 wird wird NNP cord-015369-72cjogxz 4899 5 häufig häufig NNP cord-015369-72cjogxz 4899 6 in in IN cord-015369-72cjogxz 4899 7 einem einem NNP cord-015369-72cjogxz 4899 8 Stadium Stadium NNP cord-015369-72cjogxz 4899 9 festgestellt festgestellt NNP cord-015369-72cjogxz 4899 10 , , , cord-015369-72cjogxz 4899 11 in in IN cord-015369-72cjogxz 4899 12 dem dem NNP cord-015369-72cjogxz 4899 13 lediglich lediglich NNP cord-015369-72cjogxz 4899 14 Palliation Palliation NNP cord-015369-72cjogxz 4899 15 möglich möglich NN cord-015369-72cjogxz 4899 16 ist ist NN cord-015369-72cjogxz 4899 17 . . . cord-015369-72cjogxz 4900 1 Hier Hier NNP cord-015369-72cjogxz 4900 2 liegt liegt NNP cord-015369-72cjogxz 4900 3 der der NNP cord-015369-72cjogxz 4900 4 Hauptfokus Hauptfokus NNP cord-015369-72cjogxz 4901 1 an an DT cord-015369-72cjogxz 4901 2 der der NN cord-015369-72cjogxz 4901 3 Wiederherstellung Wiederherstellung NNP cord-015369-72cjogxz 4901 4 der der NNP cord-015369-72cjogxz 4901 5 Schluckfunktion Schluckfunktion NNP cord-015369-72cjogxz 4901 6 , , , cord-015369-72cjogxz 4901 7 manchmal manchmal NNP cord-015369-72cjogxz 4901 8 ist ist NNP cord-015369-72cjogxz 4901 9 auch auch NNP cord-015369-72cjogxz 4901 10 die die VBP cord-015369-72cjogxz 4901 11 Abdichtung Abdichtung NNP cord-015369-72cjogxz 4901 12 einer einer NNP cord-015369-72cjogxz 4901 13 ösophagotrachealen ösophagotrachealen NNP cord-015369-72cjogxz 4902 1 und/ und/ LS cord-015369-72cjogxz 4903 1 oder oder NNP cord-015369-72cjogxz 4903 2 -bronchialen -bronchialen NNP cord-015369-72cjogxz 4903 3 Fistel Fistel NNP cord-015369-72cjogxz 4903 4 notwendig notwendig NNP cord-015369-72cjogxz 4903 5 . . . cord-015369-72cjogxz 4904 1 Ziel Ziel NNP cord-015369-72cjogxz 4904 2 des des FW cord-015369-72cjogxz 4904 3 eingeladenen eingeladenen NN cord-015369-72cjogxz 4905 1 Vortrages Vortrages NNP cord-015369-72cjogxz 4905 2 ist ist NNP cord-015369-72cjogxz 4905 3 es es XX cord-015369-72cjogxz 4905 4 , , , cord-015369-72cjogxz 4906 1 einen einen NNP cord-015369-72cjogxz 4906 2 Ü Ü NNP cord-015369-72cjogxz 4906 3 berblick berblick NNP cord-015369-72cjogxz 4906 4 über über NNP cord-015369-72cjogxz 4906 5 die die VBP cord-015369-72cjogxz 4907 1 endoskopischen endoskopischen NNP cord-015369-72cjogxz 4907 2 Palliationsmöglichkeiten Palliationsmöglichkeiten NNP cord-015369-72cjogxz 4907 3 zu zu NNP cord-015369-72cjogxz 4907 4 geben geben NNP cord-015369-72cjogxz 4907 5 . . . cord-015369-72cjogxz 4908 1 Methodik Methodik NNP cord-015369-72cjogxz 4908 2 . . . cord-015369-72cjogxz 4909 1 Zusammenfassung Zusammenfassung NNP cord-015369-72cjogxz 4909 2 publizierter publizierter NN cord-015369-72cjogxz 4910 1 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 4911 1 und und IN cord-015369-72cjogxz 4911 2 eigener eigener NNP cord-015369-72cjogxz 4911 3 Daten Daten NNP cord-015369-72cjogxz 4911 4 bezüglich bezüglich NNP cord-015369-72cjogxz 4911 5 der der NNP cord-015369-72cjogxz 4911 6 endoskopischen endoskopischen NNP cord-015369-72cjogxz 4911 7 Palliation Palliation NNP cord-015369-72cjogxz 4911 8 beim beim NNP cord-015369-72cjogxz 4911 9 inoperablen inoperablen NNP cord-015369-72cjogxz 4911 10 Ö Ö NNP cord-015369-72cjogxz 4911 11 sophaguskarzinom sophaguskarzinom NNP cord-015369-72cjogxz 4912 1 ( ( -LRB- cord-015369-72cjogxz 4912 2 Ablative Ablative NNP cord-015369-72cjogxz 4912 3 und und IN cord-015369-72cjogxz 4912 4 lumenerweiternde lumenerweiternde NNP cord-015369-72cjogxz 4912 5 Techniken Techniken NNP cord-015369-72cjogxz 4912 6 , , , cord-015369-72cjogxz 4912 7 Ö Ö NNP cord-015369-72cjogxz 4912 8 sophagusstents sophagusstents NNP cord-015369-72cjogxz 4912 9 , , , cord-015369-72cjogxz 4912 10 PEG PEG NNP cord-015369-72cjogxz 4912 11 ) ) -RRB- cord-015369-72cjogxz 4912 12 . . . cord-015369-72cjogxz 4913 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4913 2 . . . cord-015369-72cjogxz 4914 1 In in IN cord-015369-72cjogxz 4914 2 Ausarbeitung Ausarbeitung NNP cord-015369-72cjogxz 4914 3 ( ( -LRB- cord-015369-72cjogxz 4914 4 eingeladener eingeladener NNP cord-015369-72cjogxz 4914 5 Vortrag Vortrag NNP cord-015369-72cjogxz 4914 6 ) ) -RRB- cord-015369-72cjogxz 4914 7 . . . cord-015369-72cjogxz 4915 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 4915 2 . . . cord-015369-72cjogxz 4916 1 Bei Bei NNP cord-015369-72cjogxz 4916 2 der der NNP cord-015369-72cjogxz 4917 1 Mehrzahl Mehrzahl NNS cord-015369-72cjogxz 4917 2 der der VBP cord-015369-72cjogxz 4918 1 Patienten Patienten NNP cord-015369-72cjogxz 4918 2 sollte sollte NNP cord-015369-72cjogxz 4919 1 eine eine NNP cord-015369-72cjogxz 4919 2 weitgehend weitgehend NNP cord-015369-72cjogxz 4919 3 unabhängige unabhängige NNP cord-015369-72cjogxz 4919 4 Schluckpalliation Schluckpalliation NNP cord-015369-72cjogxz 4919 5 zu zu NNP cord-015369-72cjogxz 4919 6 erreichen erreichen NNP cord-015369-72cjogxz 4919 7 sein sein NNP cord-015369-72cjogxz 4919 8 . . . cord-015369-72cjogxz 4920 1 Probleme Probleme NNP cord-015369-72cjogxz 4920 2 ergeben ergeben NNP cord-015369-72cjogxz 4920 3 sich sich NNP cord-015369-72cjogxz 4920 4 vor vor NNP cord-015369-72cjogxz 4921 1 allem allem NNP cord-015369-72cjogxz 4921 2 bei bei NNP cord-015369-72cjogxz 4921 3 hohem hohem NNP cord-015369-72cjogxz 4921 4 Tumorsitz Tumorsitz NNP cord-015369-72cjogxz 4921 5 und und NNP cord-015369-72cjogxz 4921 6 bei bei NNP cord-015369-72cjogxz 4921 7 bestehender bestehender NNP cord-015369-72cjogxz 4921 8 ösophagotrachealer ösophagotrachealer NNP cord-015369-72cjogxz 4921 9 oder oder NNP cord-015369-72cjogxz 4921 10 -bronchialer -bronchialer NNP cord-015369-72cjogxz 4921 11 Fistel Fistel NNP cord-015369-72cjogxz 4921 12 . . . cord-015369-72cjogxz 4922 1 Implikation Implikation NNP cord-015369-72cjogxz 4922 2 Gefäßmedizin Gefäßmedizin NNP cord-015369-72cjogxz 4922 3 -Gastroenterologie -Gastroenterologie VBG cord-015369-72cjogxz 4922 4 und und IN cord-015369-72cjogxz 4922 5 Chirurgie Chirurgie NNP cord-015369-72cjogxz 4922 6 Österreichische Österreichische NNP cord-015369-72cjogxz 4922 7 Gesellschaft Gesellschaft NNP cord-015369-72cjogxz 4923 1 für für NNP cord-015369-72cjogxz 4923 2 Gefäßchirurgie Gefäßchirurgie NNP cord-015369-72cjogxz 4923 3 , , , cord-015369-72cjogxz 4923 4 Wien Wien NNP cord-015369-72cjogxz 4923 5 , , , cord-015369-72cjogxz 4923 6 Austria Austria NNP cord-015369-72cjogxz 4924 1 Die die VB cord-015369-72cjogxz 4924 2 zunehmende zunehmende NNP cord-015369-72cjogxz 4924 3 Spezialisierung Spezialisierung NNP cord-015369-72cjogxz 4925 1 und und IN cord-015369-72cjogxz 4925 2 zum zum NNP cord-015369-72cjogxz 4925 3 Teil Teil NNP cord-015369-72cjogxz 4925 4 freiwillige freiwillige NNP cord-015369-72cjogxz 4926 1 Isolation isolation NN cord-015369-72cjogxz 4926 2 der der NNP cord-015369-72cjogxz 4926 3 Fachgebiete Fachgebiete NNP cord-015369-72cjogxz 4926 4 der der NNP cord-015369-72cjogxz 4926 5 Medizin Medizin NNP cord-015369-72cjogxz 4926 6 , , , cord-015369-72cjogxz 4926 7 führt führt NNP cord-015369-72cjogxz 4926 8 dazu dazu NNP cord-015369-72cjogxz 4926 9 , , , cord-015369-72cjogxz 4926 10 dass dass NNP cord-015369-72cjogxz 4926 11 die die VBP cord-015369-72cjogxz 4926 12 Auswirkungen Auswirkungen NNP cord-015369-72cjogxz 4926 13 der der NNP cord-015369-72cjogxz 4926 14 Entwicklungen Entwicklungen NNP cord-015369-72cjogxz 4926 15 eines eine NNS cord-015369-72cjogxz 4927 1 Fachgebietes Fachgebietes NNP cord-015369-72cjogxz 4927 2 von von NNP cord-015369-72cjogxz 4927 3 den den NNP cord-015369-72cjogxz 4928 1 übrigen übrigen NNP cord-015369-72cjogxz 4928 2 Fächern Fächern NNP cord-015369-72cjogxz 4928 3 nicht nicht NNP cord-015369-72cjogxz 4928 4 mehr mehr NNP cord-015369-72cjogxz 4928 5 wahrgenommen wahrgenommen NNP cord-015369-72cjogxz 4929 1 werden werden NNP cord-015369-72cjogxz 4929 2 , , , cord-015369-72cjogxz 4929 3 sodass sodass NNP cord-015369-72cjogxz 4930 1 Folgen Folgen NNP cord-015369-72cjogxz 4930 2 einer einer NNP cord-015369-72cjogxz 4931 1 Therapie Therapie NNP cord-015369-72cjogxz 4931 2 oder oder NNP cord-015369-72cjogxz 4932 1 Prophylaxe Prophylaxe NNP cord-015369-72cjogxz 4932 2 nicht nicht FW cord-015369-72cjogxz 4932 3 richtig richtig NNP cord-015369-72cjogxz 4932 4 erkannt erkannt JJ cord-015369-72cjogxz 4932 5 und und IN cord-015369-72cjogxz 4932 6 damit damit NNP cord-015369-72cjogxz 4932 7 auch auch NNP cord-015369-72cjogxz 4932 8 nicht nicht NNP cord-015369-72cjogxz 4932 9 richtig richtig NNP cord-015369-72cjogxz 4932 10 behandelt behandelt NNP cord-015369-72cjogxz 4932 11 werden werden NNP cord-015369-72cjogxz 4932 12 . . . cord-015369-72cjogxz 4933 1 Bedauerlicherweise Bedauerlicherweise NNP cord-015369-72cjogxz 4933 2 führt führt NNP cord-015369-72cjogxz 4933 3 die die VB cord-015369-72cjogxz 4933 4 Isolierung Isolierung NNP cord-015369-72cjogxz 4933 5 der der NNP cord-015369-72cjogxz 4933 6 Fächer Fächer NNP cord-015369-72cjogxz 4933 7 auch auch JJ cord-015369-72cjogxz 4933 8 dazu dazu NNP cord-015369-72cjogxz 4933 9 , , , cord-015369-72cjogxz 4933 10 Therapieempfehlungen Therapieempfehlungen NNP cord-015369-72cjogxz 4933 11 ohne ohne NNP cord-015369-72cjogxz 4933 12 Rücksichtnahme Rücksichtnahme NNP cord-015369-72cjogxz 4933 13 auf auf NNP cord-015369-72cjogxz 4933 14 , , , cord-015369-72cjogxz 4933 15 nicht nicht NNP cord-015369-72cjogxz 4933 16 unmittelbar unmittelbar NNP cord-015369-72cjogxz 4933 17 zugehörende zugehörende NNP cord-015369-72cjogxz 4933 18 Organsysteme Organsysteme NNP cord-015369-72cjogxz 4933 19 , , , cord-015369-72cjogxz 4933 20 zu zu NNP cord-015369-72cjogxz 4933 21 erlassen erlassen NNP cord-015369-72cjogxz 4933 22 . . . cord-015369-72cjogxz 4934 1 Ö Ö NNP cord-015369-72cjogxz 4934 2 konomische konomische NNP cord-015369-72cjogxz 4934 3 Interessen Interessen NNP cord-015369-72cjogxz 4934 4 des des NNP cord-015369-72cjogxz 4934 5 Medizinalhandels Medizinalhandels NNP cord-015369-72cjogxz 4934 6 fördern fördern NNP cord-015369-72cjogxz 4935 1 mitunter mitunter NNP cord-015369-72cjogxz 4935 2 diese diese NNP cord-015369-72cjogxz 4935 3 Entwicklung Entwicklung NNP cord-015369-72cjogxz 4935 4 . . . cord-015369-72cjogxz 4936 1 In in IN cord-015369-72cjogxz 4936 2 dem dem NNP cord-015369-72cjogxz 4936 3 Referat Referat NNP cord-015369-72cjogxz 4936 4 wird wird NNP cord-015369-72cjogxz 4936 5 versucht versucht NNP cord-015369-72cjogxz 4936 6 , , , cord-015369-72cjogxz 4936 7 einerseits einerseit VBZ cord-015369-72cjogxz 4936 8 auf auf NNP cord-015369-72cjogxz 4936 9 die die VBP cord-015369-72cjogxz 4936 10 Komplikationen Komplikationen NNP cord-015369-72cjogxz 4936 11 , , , cord-015369-72cjogxz 4936 12 die die VB cord-015369-72cjogxz 4936 13 sich sich NNP cord-015369-72cjogxz 4936 14 in in IN cord-015369-72cjogxz 4936 15 Konsequenz Konsequenz NNP cord-015369-72cjogxz 4936 16 moderner modern JJR cord-015369-72cjogxz 4936 17 interventioneller interventioneller NN cord-015369-72cjogxz 4936 18 endovaskulärer endovaskulärer NNP cord-015369-72cjogxz 4936 19 Techniken Techniken NNP cord-015369-72cjogxz 4936 20 oder oder NNP cord-015369-72cjogxz 4936 21 sogenannter sogenannter NN cord-015369-72cjogxz 4936 22 Hybridtechniken Hybridtechniken NNP cord-015369-72cjogxz 4936 23 ergeben ergeben NNP cord-015369-72cjogxz 4936 24 können können NNP cord-015369-72cjogxz 4936 25 , , , cord-015369-72cjogxz 4936 26 hinzuweisen hinzuweisen NNP cord-015369-72cjogxz 4936 27 . . . cord-015369-72cjogxz 4937 1 Mit Mit NNP cord-015369-72cjogxz 4937 2 diesen diesen NNP cord-015369-72cjogxz 4937 3 Komplikationen Komplikationen NNP cord-015369-72cjogxz 4938 1 sind sind NNP cord-015369-72cjogxz 4939 1 gewöhnlich gewöhnlich NNP cord-015369-72cjogxz 4939 2 primär primär NNP cord-015369-72cjogxz 4940 1 Gastroenterologen Gastroenterologen NNP cord-015369-72cjogxz 4940 2 und und IN cord-015369-72cjogxz 4940 3 Viszeralchirurgen Viszeralchirurgen NNP cord-015369-72cjogxz 4940 4 konfrontiert konfrontiert NNP cord-015369-72cjogxz 4940 5 . . . cord-015369-72cjogxz 4941 1 Eine Eine NNP cord-015369-72cjogxz 4941 2 verzögerte verzögerte NNS cord-015369-72cjogxz 4941 3 richtige richtige NNP cord-015369-72cjogxz 4941 4 Reaktion Reaktion NNP cord-015369-72cjogxz 4941 5 auf auf NNP cord-015369-72cjogxz 4941 6 die die VBP cord-015369-72cjogxz 4941 7 ersten ersten NNP cord-015369-72cjogxz 4941 8 Symptome Symptome NNP cord-015369-72cjogxz 4941 9 verschlechtert verschlechtert NN cord-015369-72cjogxz 4941 10 die die VB cord-015369-72cjogxz 4941 11 Prognose Prognose NNP cord-015369-72cjogxz 4941 12 der der NN cord-015369-72cjogxz 4941 13 betroffenen betroffenen NNP cord-015369-72cjogxz 4942 1 Patienten Patienten NNP cord-015369-72cjogxz 4942 2 drastisch drastisch NNP cord-015369-72cjogxz 4942 3 , , , cord-015369-72cjogxz 4942 4 daher daher NNP cord-015369-72cjogxz 4942 5 ist ist NNP cord-015369-72cjogxz 4942 6 es es FW cord-015369-72cjogxz 4942 7 essenziell essenziell NNP cord-015369-72cjogxz 4942 8 , , , cord-015369-72cjogxz 4942 9 die die VB cord-015369-72cjogxz 4942 10 möglichen möglichen NNP cord-015369-72cjogxz 4942 11 unerwünschten unerwünschten VBN cord-015369-72cjogxz 4943 1 Folgen Folgen NNP cord-015369-72cjogxz 4943 2 endovaskulärer endovaskulärer NN cord-015369-72cjogxz 4943 3 Gefäßprothesen Gefäßprothesen NNP cord-015369-72cjogxz 4943 4 oder oder NN cord-015369-72cjogxz 4943 5 Stents Stents NNPS cord-015369-72cjogxz 4943 6 zu zu NNP cord-015369-72cjogxz 4943 7 kennen kennen NNP cord-015369-72cjogxz 4943 8 . . . cord-015369-72cjogxz 4944 1 Andererseits Andererseits NNP cord-015369-72cjogxz 4944 2 führen führen NNP cord-015369-72cjogxz 4944 3 gelegentlich gelegentlich NNP cord-015369-72cjogxz 4944 4 auch auch NNP cord-015369-72cjogxz 4944 5 gastroenterologische gastroenterologische NNP cord-015369-72cjogxz 4945 1 und und NNP cord-015369-72cjogxz 4946 1 viszeralchirurgische viszeralchirurgische NNP cord-015369-72cjogxz 4946 2 interventionelle interventionelle NNP cord-015369-72cjogxz 4947 1 Verfahren Verfahren NNP cord-015369-72cjogxz 4947 2 zu zu NNP cord-015369-72cjogxz 4947 3 nachhaltigen nachhaltigen NNP cord-015369-72cjogxz 4947 4 gefäßchirurgischen gefäßchirurgischen NNP cord-015369-72cjogxz 4947 5 Problemen Problemen NNP cord-015369-72cjogxz 4947 6 . . . cord-015369-72cjogxz 4948 1 Ein Ein NNP cord-015369-72cjogxz 4948 2 gemeinsamer gemeinsamer NNP cord-015369-72cjogxz 4949 1 Kongress Kongress NNP cord-015369-72cjogxz 4949 2 ist ist NN cord-015369-72cjogxz 4949 3 die die VBP cord-015369-72cjogxz 4949 4 beste beste NNP cord-015369-72cjogxz 4949 5 Gelegenheit Gelegenheit NNP cord-015369-72cjogxz 4949 6 fachübergreifend fachübergreifend NN cord-015369-72cjogxz 4950 1 konsensuell konsensuell NNP cord-015369-72cjogxz 4950 2 diese diese NNP cord-015369-72cjogxz 4950 3 Probleme Probleme NNP cord-015369-72cjogxz 4950 4 zu zu NNP cord-015369-72cjogxz 4950 5 diskutieren diskutieren FW cord-015369-72cjogxz 4950 6 . . . cord-015369-72cjogxz 4951 1 I -PRON- PRP cord-015369-72cjogxz 4952 1 m m NNP cord-015369-72cjogxz 4952 2 zweiten zweiten NNP cord-015369-72cjogxz 4952 3 Teil Teil NNP cord-015369-72cjogxz 4952 4 des des FW cord-015369-72cjogxz 4952 5 Referates Referates NNP cord-015369-72cjogxz 4952 6 wird wird NNP cord-015369-72cjogxz 4952 7 die die VBP cord-015369-72cjogxz 4952 8 prophylaktische prophylaktische NN cord-015369-72cjogxz 4952 9 cardio cardio JJ cord-015369-72cjogxz 4952 10 - - HYPH cord-015369-72cjogxz 4952 11 vasculäre vasculäre NN cord-015369-72cjogxz 4952 12 gerinnungshemmende gerinnungshemmende NNP cord-015369-72cjogxz 4952 13 Medikation Medikation NNP cord-015369-72cjogxz 4952 14 kritisch kritisch NNP cord-015369-72cjogxz 4952 15 betrachtet betrachtet NNP cord-015369-72cjogxz 4952 16 . . . cord-015369-72cjogxz 4953 1 Der Der NNP cord-015369-72cjogxz 4953 2 ü ü NN cord-015369-72cjogxz 4953 3 berbordenden berbordenden NNP cord-015369-72cjogxz 4953 4 Zahl Zahl NNP cord-015369-72cjogxz 4953 5 der der NNP cord-015369-72cjogxz 4953 6 Publikationen Publikationen NNP cord-015369-72cjogxz 4953 7 , , , cord-015369-72cjogxz 4953 8 die die VBP cord-015369-72cjogxz 4953 9 sich sich NNP cord-015369-72cjogxz 4953 10 mit mit NNP cord-015369-72cjogxz 4953 11 den den NNP cord-015369-72cjogxz 4953 12 Vorteilen Vorteilen NNP cord-015369-72cjogxz 4953 13 der der NNP cord-015369-72cjogxz 4953 14 gerinnungshemmenden gerinnungshemmenden NNP cord-015369-72cjogxz 4953 15 Medikation Medikation NNP cord-015369-72cjogxz 4953 16 befassen befassen NNP cord-015369-72cjogxz 4953 17 , , , cord-015369-72cjogxz 4953 18 steht steht NNP cord-015369-72cjogxz 4953 19 nur nur NNP cord-015369-72cjogxz 4953 20 eine eine NNP cord-015369-72cjogxz 4953 21 verschwindend verschwindend NNP cord-015369-72cjogxz 4953 22 kleine kleine NNP cord-015369-72cjogxz 4953 23 Zahl Zahl NNP cord-015369-72cjogxz 4953 24 jener jener NNP cord-015369-72cjogxz 4953 25 Publikationen Publikationen NNP cord-015369-72cjogxz 4953 26 gegenü gegenü NN cord-015369-72cjogxz 4953 27 ber ber NNP cord-015369-72cjogxz 4953 28 , , , cord-015369-72cjogxz 4954 1 die die VBP cord-015369-72cjogxz 4954 2 auf auf NNP cord-015369-72cjogxz 4954 3 die die VB cord-015369-72cjogxz 4954 4 adverse adverse JJ cord-015369-72cjogxz 4954 5 events event NNS cord-015369-72cjogxz 4954 6 , , , cord-015369-72cjogxz 4954 7 letalen letalen VBN cord-015369-72cjogxz 4954 8 Blutungen Blutungen NNP cord-015369-72cjogxz 4954 9 und und IN cord-015369-72cjogxz 4954 10 Gefahren Gefahren NNP cord-015369-72cjogxz 4954 11 hinweisen hinweisen NNP cord-015369-72cjogxz 4954 12 , , , cord-015369-72cjogxz 4955 1 mit mit NNP cord-015369-72cjogxz 4955 2 denen denen NNP cord-015369-72cjogxz 4955 3 vor vor NNP cord-015369-72cjogxz 4955 4 allem allem NNP cord-015369-72cjogxz 4955 5 die die VB cord-015369-72cjogxz 4955 6 Gastroenterologen Gastroenterologen NNP cord-015369-72cjogxz 4955 7 , , , cord-015369-72cjogxz 4955 8 Chirurgen Chirurgen NNP cord-015369-72cjogxz 4955 9 und und IN cord-015369-72cjogxz 4955 10 Gefäßchirurgen Gefäßchirurgen NNP cord-015369-72cjogxz 4955 11 konfrontiert konfrontiert NNP cord-015369-72cjogxz 4955 12 sind sind NNP cord-015369-72cjogxz 4955 13 . . . cord-015369-72cjogxz 4956 1 Kaum Kaum NNP cord-015369-72cjogxz 4956 2 eine eine NNP cord-015369-72cjogxz 4956 3 gastroenterolgische gastroenterolgische NNP cord-015369-72cjogxz 4956 4 , , , cord-015369-72cjogxz 4956 5 oder oder NNP cord-015369-72cjogxz 4956 6 chirurgische chirurgische NNP cord-015369-72cjogxz 4956 7 Abteilung Abteilung NNP cord-015369-72cjogxz 4956 8 hat hat NN cord-015369-72cjogxz 4957 1 jedoch jedoch NNP cord-015369-72cjogxz 4957 2 so so RB cord-015369-72cjogxz 4958 1 eine eine NNP cord-015369-72cjogxz 4958 2 große große NNP cord-015369-72cjogxz 4958 3 Fallzahl Fallzahl NNP cord-015369-72cjogxz 4958 4 prophylaktischmedikamentös prophylaktischmedikamentö NNS cord-015369-72cjogxz 4958 5 bedingter bedingter NN cord-015369-72cjogxz 4958 6 Blutungen Blutungen NNP cord-015369-72cjogxz 4958 7 , , , cord-015369-72cjogxz 4959 1 dass dass NNP cord-015369-72cjogxz 4959 2 eine eine NNP cord-015369-72cjogxz 4959 3 wissenschaftlich wissenschaftlich NNP cord-015369-72cjogxz 4959 4 gewichtige gewichtige NNP cord-015369-72cjogxz 4959 5 Arbeit Arbeit NNP cord-015369-72cjogxz 4959 6 entstehen entstehen NNP cord-015369-72cjogxz 4959 7 kann kann NNP cord-015369-72cjogxz 4959 8 . . . cord-015369-72cjogxz 4960 1 Nach Nach NNP cord-015369-72cjogxz 4960 2 Schätzungen Schätzungen NNP cord-015369-72cjogxz 4960 3 gibt gibt NNP cord-015369-72cjogxz 4960 4 es es NNP cord-015369-72cjogxz 4960 5 jährlich jährlich NNP cord-015369-72cjogxz 4960 6 weltweit weltweit NNP cord-015369-72cjogxz 4960 7 50.000 50.000 CD cord-015369-72cjogxz 4961 1 Tote tote NN cord-015369-72cjogxz 4961 2 als als NN cord-015369-72cjogxz 4961 3 Folge folge NN cord-015369-72cjogxz 4961 4 der der NN cord-015369-72cjogxz 4961 5 immer immer NNP cord-015369-72cjogxz 4961 6 einschneidender einschneidender NN cord-015369-72cjogxz 4961 7 in in IN cord-015369-72cjogxz 4961 8 das das NNP cord-015369-72cjogxz 4961 9 Gerinnungssystem Gerinnungssystem NNP cord-015369-72cjogxz 4961 10 eingreifenden eingreifenden NNP cord-015369-72cjogxz 4961 11 prophylaktischen prophylaktischen NNP cord-015369-72cjogxz 4961 12 Maßnahmen Maßnahmen NNP cord-015369-72cjogxz 4961 13 . . . cord-015369-72cjogxz 4962 1 Wie Wie NNP cord-015369-72cjogxz 4962 2 gehen gehen NNP cord-015369-72cjogxz 4962 3 Gastroenterologen Gastroenterologen NNP cord-015369-72cjogxz 4963 1 und und IN cord-015369-72cjogxz 4963 2 Chirurgen Chirurgen NNP cord-015369-72cjogxz 4963 3 mit mit NNP cord-015369-72cjogxz 4963 4 Patienten Patienten NNP cord-015369-72cjogxz 4964 1 um um UH cord-015369-72cjogxz 4964 2 , , , cord-015369-72cjogxz 4964 3 die die VB cord-015369-72cjogxz 4964 4 einer einer NNP cord-015369-72cjogxz 4965 1 dringenden dringenden NNP cord-015369-72cjogxz 4965 2 Intervention Intervention NNP cord-015369-72cjogxz 4965 3 bedü bedü NNP cord-015369-72cjogxz 4965 4 rfen rfen NNP cord-015369-72cjogxz 4965 5 und und NNP cord-015369-72cjogxz 4965 6 wegen wegen NNP cord-015369-72cjogxz 4965 7 eines eines NNP cord-015369-72cjogxz 4965 8 drug drug NN cord-015369-72cjogxz 4965 9 - - HYPH cord-015369-72cjogxz 4965 10 eluting elute VBG cord-015369-72cjogxz 4965 11 stents stent NNS cord-015369-72cjogxz 4965 12 eine eine NNP cord-015369-72cjogxz 4965 13 Kombination Kombination NNP cord-015369-72cjogxz 4965 14 dreier dreier NNP cord-015369-72cjogxz 4965 15 gerinnungshemmender gerinnungshemmender NN cord-015369-72cjogxz 4965 16 Medikamente Medikamente NNP cord-015369-72cjogxz 4965 17 einnehmen einnehmen NN cord-015369-72cjogxz 4965 18 mü mü NNS cord-015369-72cjogxz 4965 19 ssen ssen NNP cord-015369-72cjogxz 4965 20 , , , cord-015369-72cjogxz 4965 21 da da NNP cord-015369-72cjogxz 4965 22 es es NNP cord-015369-72cjogxz 4965 23 beim beim NNP cord-015369-72cjogxz 4965 24 Absetzen Absetzen NNP cord-015369-72cjogxz 4965 25 dieser dieser NNP cord-015369-72cjogxz 4965 26 Therapie Therapie NNP cord-015369-72cjogxz 4965 27 i i CD cord-015369-72cjogxz 4966 1 m m LS cord-015369-72cjogxz 4967 1 ersten ersten NNP cord-015369-72cjogxz 4967 2 Jahr Jahr NNP cord-015369-72cjogxz 4967 3 nach nach NNP cord-015369-72cjogxz 4967 4 Stentimplantation Stentimplantation NNP cord-015369-72cjogxz 4968 1 mit mit NNP cord-015369-72cjogxz 4968 2 großer großer JJ cord-015369-72cjogxz 4968 3 Wahrscheinlichkeit Wahrscheinlichkeit NNP cord-015369-72cjogxz 4968 4 zu zu XX cord-015369-72cjogxz 4969 1 einem einem NNP cord-015369-72cjogxz 4969 2 Sofortverschluss Sofortverschluss NNP cord-015369-72cjogxz 4969 3 und und XX cord-015369-72cjogxz 4970 1 damit damit NNP cord-015369-72cjogxz 4970 2 zu zu NNP cord-015369-72cjogxz 4971 1 einem einem NNP cord-015369-72cjogxz 4971 2 Infarkt Infarkt NNP cord-015369-72cjogxz 4971 3 Background Background NNP cord-015369-72cjogxz 4971 4 . . . cord-015369-72cjogxz 4972 1 In in IN cord-015369-72cjogxz 4972 2 2007 2007 CD cord-015369-72cjogxz 4972 3 , , , cord-015369-72cjogxz 4972 4 a a DT cord-015369-72cjogxz 4972 5 survey survey NN cord-015369-72cjogxz 4972 6 answered answer VBN cord-015369-72cjogxz 4972 7 by by IN cord-015369-72cjogxz 4972 8 667 667 CD cord-015369-72cjogxz 4972 9 members member NNS cord-015369-72cjogxz 4972 10 of of IN cord-015369-72cjogxz 4972 11 the the DT cord-015369-72cjogxz 4972 12 Austrian Austrian NNP cord-015369-72cjogxz 4972 13 Society Society NNP cord-015369-72cjogxz 4972 14 of of IN cord-015369-72cjogxz 4972 15 Surgery Surgery NNP cord-015369-72cjogxz 4972 16 revealed reveal VBD cord-015369-72cjogxz 4972 17 severe severe JJ cord-015369-72cjogxz 4972 18 problems problem NNS cord-015369-72cjogxz 4972 19 in in IN cord-015369-72cjogxz 4972 20 the the DT cord-015369-72cjogxz 4972 21 working work VBG cord-015369-72cjogxz 4972 22 conditions condition NNS cord-015369-72cjogxz 4972 23 and and CC cord-015369-72cjogxz 4972 24 a a DT cord-015369-72cjogxz 4972 25 serious serious JJ cord-015369-72cjogxz 4972 26 concern concern NN cord-015369-72cjogxz 4972 27 on on IN cord-015369-72cjogxz 4972 28 trainee trainee NN cord-015369-72cjogxz 4972 29 shortage shortage NN cord-015369-72cjogxz 4972 30 in in IN cord-015369-72cjogxz 4972 31 surgical surgical JJ cord-015369-72cjogxz 4972 32 disciplines discipline NNS cord-015369-72cjogxz 4972 33 . . . cord-015369-72cjogxz 4973 1 Methods method NNS cord-015369-72cjogxz 4973 2 . . . cord-015369-72cjogxz 4974 1 Our -PRON- PRP$ cord-015369-72cjogxz 4974 2 results result NNS cord-015369-72cjogxz 4974 3 are be VBP cord-015369-72cjogxz 4974 4 compared compare VBN cord-015369-72cjogxz 4974 5 to to IN cord-015369-72cjogxz 4974 6 those those DT cord-015369-72cjogxz 4974 7 of of IN cord-015369-72cjogxz 4974 8 a a DT cord-015369-72cjogxz 4974 9 recent recent JJ cord-015369-72cjogxz 4974 10 survey survey NN cord-015369-72cjogxz 4974 11 in in IN cord-015369-72cjogxz 4974 12 the the DT cord-015369-72cjogxz 4974 13 United United NNP cord-015369-72cjogxz 4974 14 States States NNP cord-015369-72cjogxz 4974 15 ( ( -LRB- cord-015369-72cjogxz 4974 16 mailed mail VBN cord-015369-72cjogxz 4974 17 to to IN cord-015369-72cjogxz 4974 18 all all DT cord-015369-72cjogxz 4974 19 surgeons surgeon NNS cord-015369-72cjogxz 4974 20 certified certify VBN cord-015369-72cjogxz 4974 21 by by IN cord-015369-72cjogxz 4974 22 the the DT cord-015369-72cjogxz 4974 23 American American NNP cord-015369-72cjogxz 4974 24 Board Board NNP cord-015369-72cjogxz 4974 25 of of IN cord-015369-72cjogxz 4974 26 Surgery Surgery NNP cord-015369-72cjogxz 4974 27 in in IN cord-015369-72cjogxz 4974 28 1988 1988 CD cord-015369-72cjogxz 4974 29 Surgery surgery NN cord-015369-72cjogxz 4974 30 in in IN cord-015369-72cjogxz 4974 31 , , , cord-015369-72cjogxz 4974 32 1992 1992 CD cord-015369-72cjogxz 4974 33 Surgery surgery NN cord-015369-72cjogxz 4974 34 in in IN cord-015369-72cjogxz 4974 35 , , , cord-015369-72cjogxz 4974 36 1996 1996 CD cord-015369-72cjogxz 4974 37 Surgery surgery NN cord-015369-72cjogxz 4974 38 in in RP cord-015369-72cjogxz 4974 39 , , , cord-015369-72cjogxz 4974 40 2000 2000 CD cord-015369-72cjogxz 4974 41 Surgery surgery NN cord-015369-72cjogxz 4974 42 in in IN cord-015369-72cjogxz 4974 43 and and CC cord-015369-72cjogxz 4974 44 2004 2004 CD cord-015369-72cjogxz 4974 45 895 895 CD cord-015369-72cjogxz 4974 46 respondents respondent NNS cord-015369-72cjogxz 4974 47 ; ; , cord-015369-72cjogxz 4974 48 presented present VBN cord-015369-72cjogxz 4974 49 at at IN cord-015369-72cjogxz 4974 50 the the DT cord-015369-72cjogxz 4974 51 American American NNP cord-015369-72cjogxz 4974 52 College College NNP cord-015369-72cjogxz 4974 53 of of IN cord-015369-72cjogxz 4974 54 Surgeons Surgeons NNPS cord-015369-72cjogxz 4974 55 94th 94th JJ cord-015369-72cjogxz 4974 56 Annual Annual NNP cord-015369-72cjogxz 4974 57 Clinical Clinical NNP cord-015369-72cjogxz 4974 58 Congress Congress NNP cord-015369-72cjogxz 4974 59 by by IN cord-015369-72cjogxz 4974 60 Kathrin Kathrin NNP cord-015369-72cjogxz 4974 61 M. M. NNP cord-015369-72cjogxz 4974 62 Troppmann Troppmann NNP cord-015369-72cjogxz 4974 63 ) ) -RRB- cord-015369-72cjogxz 4974 64 . . . cord-015369-72cjogxz 4975 1 Results result NNS cord-015369-72cjogxz 4975 2 . . . cord-015369-72cjogxz 4976 1 Both both DT cord-015369-72cjogxz 4976 2 surveys survey NNS cord-015369-72cjogxz 4976 3 comprised comprise VBD cord-015369-72cjogxz 4976 4 more more JJR cord-015369-72cjogxz 4976 5 than than IN cord-015369-72cjogxz 4976 6 twenty twenty CD cord-015369-72cjogxz 4976 7 questions question NNS cord-015369-72cjogxz 4976 8 each each DT cord-015369-72cjogxz 4976 9 ; ; : cord-015369-72cjogxz 4976 10 only only RB cord-015369-72cjogxz 4976 11 selected select VBN cord-015369-72cjogxz 4976 12 examples example NNS cord-015369-72cjogxz 4976 13 can can MD cord-015369-72cjogxz 4976 14 be be VB cord-015369-72cjogxz 4976 15 given give VBN cord-015369-72cjogxz 4976 16 in in IN cord-015369-72cjogxz 4976 17 this this DT cord-015369-72cjogxz 4976 18 abstract abstract NN cord-015369-72cjogxz 4976 19 . . . cord-015369-72cjogxz 4977 1 In in IN cord-015369-72cjogxz 4977 2 the the DT cord-015369-72cjogxz 4977 3 U.S. U.S. NNP cord-015369-72cjogxz 4977 4 survey survey NN cord-015369-72cjogxz 4977 5 , , , cord-015369-72cjogxz 4977 6 the the DT cord-015369-72cjogxz 4977 7 leading lead VBG cord-015369-72cjogxz 4977 8 areas area NNS cord-015369-72cjogxz 4977 9 requiring require VBG cord-015369-72cjogxz 4977 10 improvement improvement NN cord-015369-72cjogxz 4977 11 in in IN cord-015369-72cjogxz 4977 12 surgeons surgeon NNS cord-015369-72cjogxz 4977 13 ' ' POS cord-015369-72cjogxz 4977 14 quality quality NN cord-015369-72cjogxz 4977 15 of of IN cord-015369-72cjogxz 4977 16 life life NN cord-015369-72cjogxz 4977 17 were be VBD cord-015369-72cjogxz 4977 18 reimbursement reimbursement NN cord-015369-72cjogxz 4977 19 ( ( -LRB- cord-015369-72cjogxz 4977 20 93 93 CD cord-015369-72cjogxz 4977 21 % % NN cord-015369-72cjogxz 4977 22 ) ) -RRB- cord-015369-72cjogxz 4977 23 , , , cord-015369-72cjogxz 4977 24 litigation litigation NN cord-015369-72cjogxz 4977 25 ( ( -LRB- cord-015369-72cjogxz 4977 26 92 92 CD cord-015369-72cjogxz 4977 27 % % NN cord-015369-72cjogxz 4977 28 ) ) -RRB- cord-015369-72cjogxz 4977 29 and and CC cord-015369-72cjogxz 4977 30 emergency emergency NN cord-015369-72cjogxz 4977 31 calls call NNS cord-015369-72cjogxz 4977 32 ( ( -LRB- cord-015369-72cjogxz 4977 33 76 76 CD cord-015369-72cjogxz 4977 34 % % NN cord-015369-72cjogxz 4977 35 ) ) -RRB- cord-015369-72cjogxz 4977 36 . . . cord-015369-72cjogxz 4978 1 In in IN cord-015369-72cjogxz 4978 2 our -PRON- PRP$ cord-015369-72cjogxz 4978 3 survey survey NN cord-015369-72cjogxz 4978 4 , , , cord-015369-72cjogxz 4978 5 a a DT cord-015369-72cjogxz 4978 6 clear clear JJ cord-015369-72cjogxz 4978 7 majority majority NN cord-015369-72cjogxz 4978 8 worked work VBD cord-015369-72cjogxz 4978 9 60 60 CD cord-015369-72cjogxz 4978 10 - - SYM cord-015369-72cjogxz 4978 11 80 80 CD cord-015369-72cjogxz 4978 12 h h NN cord-015369-72cjogxz 4978 13 per per IN cord-015369-72cjogxz 4978 14 week week NN cord-015369-72cjogxz 4978 15 or or CC cord-015369-72cjogxz 4978 16 more more JJR cord-015369-72cjogxz 4978 17 , , , cord-015369-72cjogxz 4978 18 in in IN cord-015369-72cjogxz 4978 19 the the DT cord-015369-72cjogxz 4978 20 U.S. U.S. NNP cord-015369-72cjogxz 4979 1 the the DT cord-015369-72cjogxz 4979 2 average average JJ cord-015369-72cjogxz 4979 3 respondent respondent NN cord-015369-72cjogxz 4979 4 worked work VBD cord-015369-72cjogxz 4979 5 a a DT cord-015369-72cjogxz 4979 6 median median NN cord-015369-72cjogxz 4979 7 of of IN cord-015369-72cjogxz 4979 8 64 64 CD cord-015369-72cjogxz 4979 9 h h NN cord-015369-72cjogxz 4979 10 a a DT cord-015369-72cjogxz 4979 11 week week NN cord-015369-72cjogxz 4979 12 , , , cord-015369-72cjogxz 4979 13 but but CC cord-015369-72cjogxz 4979 14 regarded regard VBD cord-015369-72cjogxz 4979 15 50 50 CD cord-015369-72cjogxz 4979 16 h h NN cord-015369-72cjogxz 4979 17 per per IN cord-015369-72cjogxz 4979 18 week week NN cord-015369-72cjogxz 4979 19 as as IN cord-015369-72cjogxz 4979 20 ideal ideal JJ cord-015369-72cjogxz 4979 21 . . . cord-015369-72cjogxz 4980 1 In in IN cord-015369-72cjogxz 4980 2 our -PRON- PRP$ cord-015369-72cjogxz 4980 3 survey survey NN cord-015369-72cjogxz 4980 4 , , , cord-015369-72cjogxz 4980 5 only only RB cord-015369-72cjogxz 4980 6 18 18 CD cord-015369-72cjogxz 4980 7 % % NN cord-015369-72cjogxz 4980 8 were be VBD cord-015369-72cjogxz 4980 9 satisfied satisfied JJ cord-015369-72cjogxz 4980 10 with with IN cord-015369-72cjogxz 4980 11 payment payment NN cord-015369-72cjogxz 4980 12 , , , cord-015369-72cjogxz 4980 13 in in IN cord-015369-72cjogxz 4980 14 the the DT cord-015369-72cjogxz 4980 15 U.S. U.S. NNP cord-015369-72cjogxz 4980 16 26 26 CD cord-015369-72cjogxz 4980 17 % % NN cord-015369-72cjogxz 4980 18 were be VBD cord-015369-72cjogxz 4980 19 content content JJ cord-015369-72cjogxz 4980 20 with with IN cord-015369-72cjogxz 4980 21 their -PRON- PRP$ cord-015369-72cjogxz 4980 22 reimbursement reimbursement NN cord-015369-72cjogxz 4980 23 with with IN cord-015369-72cjogxz 4980 24 respect respect NN cord-015369-72cjogxz 4980 25 to to IN cord-015369-72cjogxz 4980 26 the the DT cord-015369-72cjogxz 4980 27 total total JJ cord-015369-72cjogxz 4980 28 number number NN cord-015369-72cjogxz 4980 29 of of IN cord-015369-72cjogxz 4980 30 hours hour NNS cord-015369-72cjogxz 4980 31 worked work VBD cord-015369-72cjogxz 4980 32 , , , cord-015369-72cjogxz 4980 33 but but CC cord-015369-72cjogxz 4980 34 only only RB cord-015369-72cjogxz 4980 35 16 16 CD cord-015369-72cjogxz 4980 36 % % NN cord-015369-72cjogxz 4980 37 were be VBD cord-015369-72cjogxz 4980 38 satisfied satisfied JJ cord-015369-72cjogxz 4980 39 in in IN cord-015369-72cjogxz 4980 40 view view NN cord-015369-72cjogxz 4980 41 of of IN cord-015369-72cjogxz 4980 42 their -PRON- PRP$ cord-015369-72cjogxz 4980 43 unpredictable unpredictable JJ cord-015369-72cjogxz 4980 44 schedule schedule NN cord-015369-72cjogxz 4980 45 and and CC cord-015369-72cjogxz 4980 46 14 14 CD cord-015369-72cjogxz 4980 47 % % NN cord-015369-72cjogxz 4980 48 when when WRB cord-015369-72cjogxz 4980 49 considering consider VBG cord-015369-72cjogxz 4980 50 their -PRON- PRP$ cord-015369-72cjogxz 4980 51 responsibility responsibility NN cord-015369-72cjogxz 4980 52 for for IN cord-015369-72cjogxz 4980 53 patients patient NNS cord-015369-72cjogxz 4980 54 ' ' POS cord-015369-72cjogxz 4980 55 health health NN cord-015369-72cjogxz 4980 56 and and CC cord-015369-72cjogxz 4980 57 lives life NNS cord-015369-72cjogxz 4980 58 . . . cord-015369-72cjogxz 4981 1 Conclusions conclusion NNS cord-015369-72cjogxz 4981 2 . . . cord-015369-72cjogxz 4982 1 Although although IN cord-015369-72cjogxz 4982 2 circumstances circumstance NNS cord-015369-72cjogxz 4982 3 vary vary VBP cord-015369-72cjogxz 4982 4 , , , cord-015369-72cjogxz 4982 5 the the DT cord-015369-72cjogxz 4982 6 results result NNS cord-015369-72cjogxz 4982 7 of of IN cord-015369-72cjogxz 4982 8 these these DT cord-015369-72cjogxz 4982 9 two two CD cord-015369-72cjogxz 4982 10 surveys survey NNS cord-015369-72cjogxz 4982 11 show show VBP cord-015369-72cjogxz 4982 12 that that IN cord-015369-72cjogxz 4982 13 many many JJ cord-015369-72cjogxz 4982 14 pressing press VBG cord-015369-72cjogxz 4982 15 questions question NNS cord-015369-72cjogxz 4982 16 are be VBP cord-015369-72cjogxz 4982 17 the the DT cord-015369-72cjogxz 4982 18 same same JJ cord-015369-72cjogxz 4982 19 and and CC cord-015369-72cjogxz 4982 20 must must MD cord-015369-72cjogxz 4982 21 be be VB cord-015369-72cjogxz 4982 22 tackled tackle VBN cord-015369-72cjogxz 4982 23 in in IN cord-015369-72cjogxz 4982 24 order order NN cord-015369-72cjogxz 4982 25 to to TO cord-015369-72cjogxz 4982 26 overcome overcome VB cord-015369-72cjogxz 4982 27 the the DT cord-015369-72cjogxz 4982 28 prevailing prevail VBG cord-015369-72cjogxz 4982 29 problems problem NNS cord-015369-72cjogxz 4982 30 in in IN cord-015369-72cjogxz 4982 31 working work VBG cord-015369-72cjogxz 4982 32 conditions condition NNS cord-015369-72cjogxz 4982 33 and and CC cord-015369-72cjogxz 4982 34 the the DT cord-015369-72cjogxz 4982 35 threat threat NN cord-015369-72cjogxz 4982 36 of of IN cord-015369-72cjogxz 4982 37 trainee trainee NN cord-015369-72cjogxz 4982 38 shortage shortage NN cord-015369-72cjogxz 4982 39 / / SYM cord-015369-72cjogxz 4982 40 resident resident JJ cord-015369-72cjogxz 4982 41 attrition attrition NN cord-015369-72cjogxz 4982 42 in in IN cord-015369-72cjogxz 4982 43 surgical surgical JJ cord-015369-72cjogxz 4982 44 disciplines discipline NNS cord-015369-72cjogxz 4982 45 . . . cord-015369-72cjogxz 4983 1 Working working NN cord-015369-72cjogxz 4983 2 models model NNS cord-015369-72cjogxz 4983 3 in in IN cord-015369-72cjogxz 4983 4 surgery surgery NN cord-015369-72cjogxz 4983 5 Grundlagen Grundlagen NNP cord-015369-72cjogxz 4983 6 . . . cord-015369-72cjogxz 4984 1 In in IN cord-015369-72cjogxz 4984 2 den den NNP cord-015369-72cjogxz 4984 3 letzten letzten NNP cord-015369-72cjogxz 4984 4 Jahren Jahren NNP cord-015369-72cjogxz 4984 5 gelang gelang NNP cord-015369-72cjogxz 4984 6 es es NNP cord-015369-72cjogxz 4984 7 deutliche deutliche NNP cord-015369-72cjogxz 4984 8 Fortschritte Fortschritte NNP cord-015369-72cjogxz 4984 9 in in IN cord-015369-72cjogxz 4984 10 der der NN cord-015369-72cjogxz 4984 11 personalisierten personalisierten NNP cord-015369-72cjogxz 4984 12 Krebstherapie Krebstherapie NNP cord-015369-72cjogxz 4984 13 zu zu NNP cord-015369-72cjogxz 4984 14 erzielen erzielen NNP cord-015369-72cjogxz 4984 15 . . . cord-015369-72cjogxz 4985 1 Praediktive Praediktive NNP cord-015369-72cjogxz 4985 2 Marker Marker NNP cord-015369-72cjogxz 4985 3 wurden wurden NNS cord-015369-72cjogxz 4985 4 entdeckt entdeckt NNS cord-015369-72cjogxz 4985 5 die die VBP cord-015369-72cjogxz 4986 1 bei bei NNP cord-015369-72cjogxz 4986 2 manchen manchen NNP cord-015369-72cjogxz 4986 3 Patienten Patienten NNP cord-015369-72cjogxz 4986 4 ein ein NNP cord-015369-72cjogxz 4987 1 Ansprechen Ansprechen NNP cord-015369-72cjogxz 4987 2 auf auf NNP cord-015369-72cjogxz 4987 3 eine eine NNP cord-015369-72cjogxz 4987 4 bestimmte bestimmte JJ cord-015369-72cjogxz 4987 5 Therapie Therapie NNP cord-015369-72cjogxz 4987 6 erwarten erwarten NNP cord-015369-72cjogxz 4987 7 lassen lassen NNP cord-015369-72cjogxz 4987 8 bzw bzw NNP cord-015369-72cjogxz 4987 9 . . . cord-015369-72cjogxz 4988 1 anderen anderen NNP cord-015369-72cjogxz 4988 2 Patienten Patienten NNP cord-015369-72cjogxz 4988 3 eine eine NNP cord-015369-72cjogxz 4988 4 sinnlose sinnlose NNPS cord-015369-72cjogxz 4988 5 , , , cord-015369-72cjogxz 4988 6 teure teure NN cord-015369-72cjogxz 4988 7 und und NNP cord-015369-72cjogxz 4988 8 belastende belastende NNP cord-015369-72cjogxz 4988 9 Therapie Therapie NNP cord-015369-72cjogxz 4988 10 ersparen ersparen NNP cord-015369-72cjogxz 4988 11 . . . cord-015369-72cjogxz 4989 1 Aber Aber NNP cord-015369-72cjogxz 4989 2 auch auch NNP cord-015369-72cjogxz 4989 3 mit mit NNP cord-015369-72cjogxz 4989 4 bildgebenden bildgebenden VBD cord-015369-72cjogxz 4989 5 Verfahren Verfahren NNP cord-015369-72cjogxz 4989 6 ist ist NNP cord-015369-72cjogxz 4989 7 eine eine NNP cord-015369-72cjogxz 4989 8 Beurteilung Beurteilung NNP cord-015369-72cjogxz 4989 9 des des NNP cord-015369-72cjogxz 4989 10 Therapiansprechens Therapiansprechens NNP cord-015369-72cjogxz 4989 11 möglich möglich NN cord-015369-72cjogxz 4989 12 geworden geworden NN cord-015369-72cjogxz 4989 13 . . . cord-015369-72cjogxz 4990 1 Die die VB cord-015369-72cjogxz 4990 2 Auswirkungen Auswirkungen NNP cord-015369-72cjogxz 4990 3 dieser dieser NNP cord-015369-72cjogxz 4990 4 Entwicklungen Entwicklungen NNP cord-015369-72cjogxz 4990 5 auf auf NNP cord-015369-72cjogxz 4990 6 die die NNP cord-015369-72cjogxz 4990 7 onkologische onkologische NN cord-015369-72cjogxz 4991 1 Chirurgie Chirurgie NNP cord-015369-72cjogxz 4991 2 werden werden NNP cord-015369-72cjogxz 4991 3 diskutiert diskutiert NNP cord-015369-72cjogxz 4991 4 . . . cord-015369-72cjogxz 4992 1 Methodik Methodik NNP cord-015369-72cjogxz 4992 2 . . . cord-015369-72cjogxz 4993 1 Die die VB cord-015369-72cjogxz 4993 2 wissenschaftliche wissenschaftliche JJ cord-015369-72cjogxz 4993 3 Literatur Literatur NNP cord-015369-72cjogxz 4994 1 und und NNP cord-015369-72cjogxz 4994 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4994 3 entsprechender entsprechender NNP cord-015369-72cjogxz 4995 1 Studien Studien NNP cord-015369-72cjogxz 4995 2 werden werden NNP cord-015369-72cjogxz 4995 3 evaluiert evaluiert NNP cord-015369-72cjogxz 4996 1 und und NNP cord-015369-72cjogxz 4997 1 i -PRON- PRP cord-015369-72cjogxz 4997 2 m be VBP cord-015369-72cjogxz 4997 3 Kontext Kontext NNP cord-015369-72cjogxz 4997 4 der der NNP cord-015369-72cjogxz 4997 5 eigenen eigenen NNP cord-015369-72cjogxz 4998 1 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 4998 2 beurteilt beurteilt NNP cord-015369-72cjogxz 4998 3 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 4998 4 . . . cord-015369-72cjogxz 4999 1 Es Es NNP cord-015369-72cjogxz 4999 2 gibt gibt NNP cord-015369-72cjogxz 4999 3 zahlreiche zahlreiche NNP cord-015369-72cjogxz 4999 4 Ansätze Ansätze NNP cord-015369-72cjogxz 4999 5 um um UH cord-015369-72cjogxz 4999 6 das das NNP cord-015369-72cjogxz 4999 7 Therapieansprechen Therapieansprechen NNP cord-015369-72cjogxz 4999 8 für für IN cord-015369-72cjogxz 4999 9 den den NNP cord-015369-72cjogxz 4999 10 einzelnen einzelnen NNP cord-015369-72cjogxz 4999 11 Patienten Patienten NNP cord-015369-72cjogxz 4999 12 vorherzusagen vorherzusagen NN cord-015369-72cjogxz 4999 13 . . . cord-015369-72cjogxz 5000 1 Dies die VBZ cord-015369-72cjogxz 5000 2 gilt gilt NN cord-015369-72cjogxz 5000 3 für für FW cord-015369-72cjogxz 5000 4 vor vor NNP cord-015369-72cjogxz 5000 5 allem allem NNP cord-015369-72cjogxz 5000 6 für für NNP cord-015369-72cjogxz 5000 7 systemische systemische NNP cord-015369-72cjogxz 5001 1 ( ( -LRB- cord-015369-72cjogxz 5001 2 neoadjuvante neoadjuvante NNP cord-015369-72cjogxz 5001 3 , , , cord-015369-72cjogxz 5001 4 adjuvante adjuvante NNP cord-015369-72cjogxz 5001 5 oder oder NNP cord-015369-72cjogxz 5001 6 palliative palliative NNP cord-015369-72cjogxz 5001 7 ) ) -RRB- cord-015369-72cjogxz 5002 1 Therapien Therapien NNP cord-015369-72cjogxz 5002 2 aber aber NNP cord-015369-72cjogxz 5002 3 auch auch NNP cord-015369-72cjogxz 5002 4 für für NNP cord-015369-72cjogxz 5002 5 die die VBP cord-015369-72cjogxz 5002 6 Strahlentherapie Strahlentherapie NNP cord-015369-72cjogxz 5002 7 . . . cord-015369-72cjogxz 5003 1 Die die VB cord-015369-72cjogxz 5003 2 Bedeutung Bedeutung NNP cord-015369-72cjogxz 5003 3 für für IN cord-015369-72cjogxz 5003 4 den den NNP cord-015369-72cjogxz 5003 5 rein rein NNP cord-015369-72cjogxz 5003 6 chirurgischen chirurgischen NNP cord-015369-72cjogxz 5004 1 Teil Teil NNP cord-015369-72cjogxz 5004 2 des des FW cord-015369-72cjogxz 5004 3 multidisziplinären multidisziplinären NNP cord-015369-72cjogxz 5004 4 Managements management NNS cord-015369-72cjogxz 5004 5 dieser dieser NNP cord-015369-72cjogxz 5004 6 Patienten Patienten NNP cord-015369-72cjogxz 5004 7 ist ist NNP cord-015369-72cjogxz 5004 8 allerdings allerdings NNP cord-015369-72cjogxz 5004 9 limitiert limitiert JJ cord-015369-72cjogxz 5004 10 . . . cord-015369-72cjogxz 5005 1 Dabei Dabei NNP cord-015369-72cjogxz 5005 2 sind sind NNP cord-015369-72cjogxz 5006 1 unterschiedliche unterschiedliche NNP cord-015369-72cjogxz 5006 2 Entscheidungen Entscheidungen NNP cord-015369-72cjogxz 5006 3 zu zu NNP cord-015369-72cjogxz 5006 4 treffen treffen NNP cord-015369-72cjogxz 5006 5 , , , cord-015369-72cjogxz 5006 6 für für NNP cord-015369-72cjogxz 5006 7 Patienten Patienten NNP cord-015369-72cjogxz 5006 8 die die VBP cord-015369-72cjogxz 5006 9 mit mit NNP cord-015369-72cjogxz 5006 10 primär primär NNP cord-015369-72cjogxz 5006 11 unresektablen unresektablen NNP cord-015369-72cjogxz 5006 12 Tumoren Tumoren NNP cord-015369-72cjogxz 5006 13 behandelt behandelt NNP cord-015369-72cjogxz 5006 14 werden werden NNP cord-015369-72cjogxz 5007 1 und und IN cord-015369-72cjogxz 5007 2 resektabel resektabel NNP cord-015369-72cjogxz 5007 3 werden werden NNP cord-015369-72cjogxz 5007 4 , , , cord-015369-72cjogxz 5007 5 für für NNP cord-015369-72cjogxz 5007 6 Patienten Patienten NNP cord-015369-72cjogxz 5008 1 die die VB cord-015369-72cjogxz 5008 2 unter unter NNP cord-015369-72cjogxz 5008 3 einer einer JJ cord-015369-72cjogxz 5008 4 neoadjuvanten neoadjuvanten NNP cord-015369-72cjogxz 5008 5 Therapie Therapie NNP cord-015369-72cjogxz 5008 6 progredient progredient NN cord-015369-72cjogxz 5008 7 sind sind NNP cord-015369-72cjogxz 5008 8 und und XX cord-015369-72cjogxz 5009 1 Patienten Patienten NNP cord-015369-72cjogxz 5009 2 mit mit NNP cord-015369-72cjogxz 5009 3 bereits bereits NNP cord-015369-72cjogxz 5009 4 primär primär NNP cord-015369-72cjogxz 5010 1 resektablen resektablen NNP cord-015369-72cjogxz 5010 2 Tumor Tumor NNP cord-015369-72cjogxz 5010 3 die die VBP cord-015369-72cjogxz 5010 4 einen einen FW cord-015369-72cjogxz 5010 5 guten guten JJ cord-015369-72cjogxz 5010 6 Respose Respose NNP cord-015369-72cjogxz 5010 7 auf auf NNP cord-015369-72cjogxz 5010 8 eine eine NNP cord-015369-72cjogxz 5010 9 neoadjuvante neoadjuvante FW cord-015369-72cjogxz 5010 10 Therapie Therapie NNP cord-015369-72cjogxz 5010 11 zeigen zeigen NNP cord-015369-72cjogxz 5010 12 . . . cord-015369-72cjogxz 5011 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 5011 2 . . . cord-015369-72cjogxz 5012 1 Die die VB cord-015369-72cjogxz 5012 2 individualisierte individualisierte NNS cord-015369-72cjogxz 5012 3 onkologische onkologische NN cord-015369-72cjogxz 5012 4 Therapie Therapie NNP cord-015369-72cjogxz 5012 5 ist ist NN cord-015369-72cjogxz 5012 6 von von NNP cord-015369-72cjogxz 5012 7 eminenter eminent JJR cord-015369-72cjogxz 5012 8 Bedeutung Bedeutung NNP cord-015369-72cjogxz 5012 9 für für IN cord-015369-72cjogxz 5012 10 die die VBP cord-015369-72cjogxz 5012 11 Behandlung Behandlung NNP cord-015369-72cjogxz 5012 12 unserer unserer NNP cord-015369-72cjogxz 5012 13 Patienten Patienten NNP cord-015369-72cjogxz 5012 14 hinsichtlich hinsichtlich NNP cord-015369-72cjogxz 5013 1 Vermeidung Vermeidung NNP cord-015369-72cjogxz 5013 2 unnotwendiger unnotwendiger NN cord-015369-72cjogxz 5014 1 Nebenwirkungen Nebenwirkungen NNP cord-015369-72cjogxz 5014 2 und und IN cord-015369-72cjogxz 5014 3 sinnloser sinnloser NNP cord-015369-72cjogxz 5014 4 und und IN cord-015369-72cjogxz 5014 5 teurer teurer NNP cord-015369-72cjogxz 5014 6 Therapien Therapien NNP cord-015369-72cjogxz 5014 7 bzw bzw NNP cord-015369-72cjogxz 5014 8 . . . cord-015369-72cjogxz 5015 1 für für NNP cord-015369-72cjogxz 5015 2 das das NNP cord-015369-72cjogxz 5015 3 gesamte gesamte NNP cord-015369-72cjogxz 5015 4 onkologischem onkologischem NNP cord-015369-72cjogxz 5015 5 Management Management NNP cord-015369-72cjogxz 5015 6 . . . cord-015369-72cjogxz 5016 1 Für Für NNP cord-015369-72cjogxz 5016 2 die die VBP cord-015369-72cjogxz 5016 3 Chirurgie Chirurgie NNP cord-015369-72cjogxz 5016 4 ergeben ergeben NNP cord-015369-72cjogxz 5016 5 sich sich NNP cord-015369-72cjogxz 5016 6 außer außer NNP cord-015369-72cjogxz 5017 1 i -PRON- PRP cord-015369-72cjogxz 5017 2 m be VBP cord-015369-72cjogxz 5017 3 Rahmen Rahmen NNP cord-015369-72cjogxz 5017 4 der der NNP cord-015369-72cjogxz 5017 5 multidisziplinären multidisziplinären NNP cord-015369-72cjogxz 5017 6 Planung Planung NNP cord-015369-72cjogxz 5017 7 derzeit derzeit NNP cord-015369-72cjogxz 5017 8 noch noch NNP cord-015369-72cjogxz 5017 9 wenig wenig NNP cord-015369-72cjogxz 5017 10 Konsequenzen Konsequenzen NNP cord-015369-72cjogxz 5017 11 . . . cord-015369-72cjogxz 5018 1 Anforderungen Anforderungen NNP cord-015369-72cjogxz 5018 2 an an DT cord-015369-72cjogxz 5018 3 die die NN cord-015369-72cjogxz 5019 1 Chirurgie Chirurgie NNP cord-015369-72cjogxz 5019 2 durch durch NNP cord-015369-72cjogxz 5019 3 Individualisierung Individualisierung NNP cord-015369-72cjogxz 5019 4 der der NN cord-015369-72cjogxz 5019 5 Therapie Therapie NNP cord-015369-72cjogxz 5019 6 mittels mittels NNP cord-015369-72cjogxz 5019 7 Genexpressionsanalyse Genexpressionsanalyse NNP cord-015369-72cjogxz 5020 1 beim beim NNP cord-015369-72cjogxz 5020 2 Mammakarzinom Mammakarzinom NNP cord-015369-72cjogxz 5020 3 Die die VB cord-015369-72cjogxz 5021 1 Chirurgie Chirurgie NNP cord-015369-72cjogxz 5021 2 i -PRON- PRP cord-015369-72cjogxz 5021 3 m be VBP cord-015369-72cjogxz 5022 1 zentralen zentralen NNP cord-015369-72cjogxz 5022 2 case case NN cord-015369-72cjogxz 5023 1 management management NN cord-015369-72cjogxz 5023 2 bei bei NNP cord-015369-72cjogxz 5023 3 der der NNP cord-015369-72cjogxz 5023 4 Behandlung Behandlung NNP cord-015369-72cjogxz 5023 5 des des NNP cord-015369-72cjogxz 5024 1 Mammakarzinoms Mammakarzinoms NNP cord-015369-72cjogxz 5024 2 steht steht NNP cord-015369-72cjogxz 5024 3 neuen neuen JJ cord-015369-72cjogxz 5025 1 und und NNP cord-015369-72cjogxz 5025 2 wachsenden wachsenden NNP cord-015369-72cjogxz 5025 3 Anforderungen Anforderungen NNP cord-015369-72cjogxz 5025 4 gegenüber gegenüber NNP cord-015369-72cjogxz 5025 5 . . . cord-015369-72cjogxz 5026 1 Die die VB cord-015369-72cjogxz 5026 2 individualisierte individualisierte NNS cord-015369-72cjogxz 5026 3 Therapie Therapie NNP cord-015369-72cjogxz 5026 4 hat hat NN cord-015369-72cjogxz 5026 5 mit mit NNP cord-015369-72cjogxz 5026 6 Bestimmung Bestimmung NNP cord-015369-72cjogxz 5026 7 von von NNP cord-015369-72cjogxz 5026 8 Hormonrezeptoren Hormonrezeptoren NNP cord-015369-72cjogxz 5026 9 und und IN cord-015369-72cjogxz 5027 1 Her2 Her2 NNP cord-015369-72cjogxz 5027 2 / / SYM cord-015369-72cjogxz 5027 3 neu neu NNP cord-015369-72cjogxz 5027 4 - - HYPH cord-015369-72cjogxz 5027 5 Status Status NNP cord-015369-72cjogxz 5027 6 erst erst RB cord-015369-72cjogxz 5027 7 begonnen begonnen '' cord-015369-72cjogxz 5027 8 -in -in . cord-015369-72cjogxz 5028 1 den den NNP cord-015369-72cjogxz 5028 2 letzten letzten NNP cord-015369-72cjogxz 5028 3 Jahren Jahren NNP cord-015369-72cjogxz 5028 4 haben haben NNP cord-015369-72cjogxz 5028 5 Techniken Techniken NNP cord-015369-72cjogxz 5028 6 wie wie NNP cord-015369-72cjogxz 5028 7 Genexpressionsanalysen Genexpressionsanalysen NNP cord-015369-72cjogxz 5028 8 die die VBP cord-015369-72cjogxz 5029 1 Erstellung Erstellung NNP cord-015369-72cjogxz 5029 2 einer einer NNP cord-015369-72cjogxz 5029 3 individuellen individuellen VBD cord-015369-72cjogxz 5029 4 und und IN cord-015369-72cjogxz 5029 5 besseren besseren NNP cord-015369-72cjogxz 5029 6 Prognose Prognose NNP cord-015369-72cjogxz 5029 7 als als NNP cord-015369-72cjogxz 5029 8 mit mit NNP cord-015369-72cjogxz 5029 9 klassischen klassischen NNP cord-015369-72cjogxz 5029 10 klinisch klinisch NNP cord-015369-72cjogxz 5029 11 - - HYPH cord-015369-72cjogxz 5029 12 pathologischen pathologischen NNP cord-015369-72cjogxz 5029 13 Parametern Parametern NNP cord-015369-72cjogxz 5029 14 ermöglicht ermöglicht NNP cord-015369-72cjogxz 5029 15 . . . cord-015369-72cjogxz 5030 1 Genexpressionsanalysen Genexpressionsanalysen NNP cord-015369-72cjogxz 5030 2 werden werden NNP cord-015369-72cjogxz 5030 3 in in IN cord-015369-72cjogxz 5030 4 vielen vielen NNP cord-015369-72cjogxz 5030 5 Institutionen Institutionen NNP cord-015369-72cjogxz 5030 6 bereits bereits NNP cord-015369-72cjogxz 5030 7 routinemäßig routinemäßig NNP cord-015369-72cjogxz 5030 8 durchgefü durchgefü NNP cord-015369-72cjogxz 5031 1 hrt hrt NNP cord-015369-72cjogxz 5031 2 und und NNP cord-015369-72cjogxz 5031 3 wurden wurden NNP cord-015369-72cjogxz 5031 4 zum zum NNP cord-015369-72cjogxz 5031 5 Teil Teil NNP cord-015369-72cjogxz 5031 6 bereits bereits NNP cord-015369-72cjogxz 5031 7 in in IN cord-015369-72cjogxz 5031 8 Therapierichtlinien Therapierichtlinien NNP cord-015369-72cjogxz 5031 9 integriert integriert NNP cord-015369-72cjogxz 5032 1 ( ( -LRB- cord-015369-72cjogxz 5032 2 NCCN NCCN NNP cord-015369-72cjogxz 5032 3 þ þ NNP cord-015369-72cjogxz 5032 4 ASCO ASCO NNP cord-015369-72cjogxz 5032 5 - - HYPH cord-015369-72cjogxz 5032 6 guidelines guideline NNS cord-015369-72cjogxz 5032 7 ) ) -RRB- cord-015369-72cjogxz 5032 8 . . . cord-015369-72cjogxz 5033 1 Die die VB cord-015369-72cjogxz 5033 2 Indikationen Indikationen NNP cord-015369-72cjogxz 5034 1 fü fü IN cord-015369-72cjogxz 5034 2 r r NNP cord-015369-72cjogxz 5034 3 diese diese NNP cord-015369-72cjogxz 5034 4 Tests Tests NNP cord-015369-72cjogxz 5034 5 werden werden NNP cord-015369-72cjogxz 5034 6 jetzt jetzt NNP cord-015369-72cjogxz 5034 7 zunehmend zunehmend NNP cord-015369-72cjogxz 5034 8 erweitert erweitert NNP cord-015369-72cjogxz 5034 9 : : : cord-015369-72cjogxz 5035 1 während während NNP cord-015369-72cjogxz 5035 2 einerseits einerseits NNP cord-015369-72cjogxz 5035 3 auch auch NNP cord-015369-72cjogxz 5035 4 diejenigen diejenigen NNP cord-015369-72cjogxz 5035 5 kleinen kleinen NNP cord-015369-72cjogxz 5035 6 Tumoren Tumoren NNP cord-015369-72cjogxz 5035 7 , , , cord-015369-72cjogxz 5035 8 welche welche NNP cord-015369-72cjogxz 5035 9 metastasieren metastasieren NNP cord-015369-72cjogxz 5036 1 können können NNP cord-015369-72cjogxz 5036 2 , , , cord-015369-72cjogxz 5036 3 z. z. NNP cord-015369-72cjogxz 5037 1 B. B. NNP cord-015369-72cjogxz 5037 2 durch durch NNP cord-015369-72cjogxz 5037 3 das das NNP cord-015369-72cjogxz 5037 4 70-Genexpressionsprofil 70-genexpressionsprofil CD cord-015369-72cjogxz 5037 5 MammaPrint MammaPrint NNP cord-015369-72cjogxz 5037 6 identifiziert identifiziert NN cord-015369-72cjogxz 5038 1 und und IN cord-015369-72cjogxz 5038 2 einer einer NNP cord-015369-72cjogxz 5039 1 notwendigen notwendigen NNP cord-015369-72cjogxz 5039 2 adjuvanten adjuvanten NNP cord-015369-72cjogxz 5039 3 Therapie Therapie NNP cord-015369-72cjogxz 5039 4 zugefü zugefü NNP cord-015369-72cjogxz 5039 5 hrt hrt NNP cord-015369-72cjogxz 5039 6 werden werden NNP cord-015369-72cjogxz 5039 7 können können NNP cord-015369-72cjogxz 5040 1 , , , cord-015369-72cjogxz 5040 2 gibt gibt NNP cord-015369-72cjogxz 5040 3 es es NNP cord-015369-72cjogxz 5040 4 andererseits andererseits NNP cord-015369-72cjogxz 5040 5 auch auch NNP cord-015369-72cjogxz 5040 6 in in IN cord-015369-72cjogxz 5040 7 Hochrisikogruppen Hochrisikogruppen NNP cord-015369-72cjogxz 5040 8 wie wie XX cord-015369-72cjogxz 5040 9 Her2-positiven her2-positiven XX cord-015369-72cjogxz 5041 1 Karzinomen Karzinomen NNP cord-015369-72cjogxz 5041 2 einen einen NNP cord-015369-72cjogxz 5041 3 Teil Teil NNP cord-015369-72cjogxz 5041 4 mit mit NNP cord-015369-72cjogxz 5041 5 guter guter NNP cord-015369-72cjogxz 5041 6 Prognose Prognose NNP cord-015369-72cjogxz 5041 7 , , , cord-015369-72cjogxz 5041 8 der der NNP cord-015369-72cjogxz 5041 9 vielleicht vielleicht NNP cord-015369-72cjogxz 5041 10 kei kei NNP cord-015369-72cjogxz 5041 11 - - HYPH cord-015369-72cjogxz 5041 12 ner ner NNP cord-015369-72cjogxz 5041 13 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 5041 14 bedarf bedarf NN cord-015369-72cjogxz 5041 15 . . . cord-015369-72cjogxz 5042 1 Diese Diese NNP cord-015369-72cjogxz 5042 2 Multigenassays Multigenassays NNP cord-015369-72cjogxz 5042 3 erweisen erweisen NNP cord-015369-72cjogxz 5042 4 sind sind NNP cord-015369-72cjogxz 5042 5 nicht nicht NNP cord-015369-72cjogxz 5042 6 nur nur NNP cord-015369-72cjogxz 5042 7 als als CD cord-015369-72cjogxz 5042 8 prognostisch prognostisch NNP cord-015369-72cjogxz 5042 9 , , , cord-015369-72cjogxz 5042 10 sondern sondern NNP cord-015369-72cjogxz 5042 11 zunehmend zunehmend NNP cord-015369-72cjogxz 5042 12 auch auch NNP cord-015369-72cjogxz 5042 13 als als NNP cord-015369-72cjogxz 5042 14 prädiktiv prädiktiv NNP cord-015369-72cjogxz 5043 1 fü fü IN cord-015369-72cjogxz 5043 2 r r NNP cord-015369-72cjogxz 5043 3 das das NNP cord-015369-72cjogxz 5043 4 Ansprechen Ansprechen NNP cord-015369-72cjogxz 5043 5 auf auf NNP cord-015369-72cjogxz 5043 6 ( ( -LRB- cord-015369-72cjogxz 5043 7 neo)adjuvante neo)adjuvante RB cord-015369-72cjogxz 5044 1 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 5045 1 und und NNP cord-015369-72cjogxz 5045 2 wir wir NNP cord-015369-72cjogxz 5045 3 wissen wissen NNP cord-015369-72cjogxz 5045 4 immer immer NNP cord-015369-72cjogxz 5045 5 mehr mehr NNP cord-015369-72cjogxz 5045 6 , , , cord-015369-72cjogxz 5045 7 wer wer NNP cord-015369-72cjogxz 5045 8 von von NNP cord-015369-72cjogxz 5045 9 welcher welcher NNP cord-015369-72cjogxz 5045 10 Therapie Therapie NNP cord-015369-72cjogxz 5045 11 profitiert profitiert NNP cord-015369-72cjogxz 5045 12 , , , cord-015369-72cjogxz 5045 13 was be VBD cord-015369-72cjogxz 5045 14 essentiell essentiell NNP cord-015369-72cjogxz 5045 15 sein sein NNP cord-015369-72cjogxz 5045 16 wird wird NNP cord-015369-72cjogxz 5045 17 fü fü NNP cord-015369-72cjogxz 5046 1 r r LS cord-015369-72cjogxz 5046 2 die die VB cord-015369-72cjogxz 5047 1 notwendige notwendige NNP cord-015369-72cjogxz 5047 2 Kosteneindämmung Kosteneindämmung NNP cord-015369-72cjogxz 5047 3 und und IN cord-015369-72cjogxz 5047 4 Vermeidung Vermeidung NNP cord-015369-72cjogxz 5047 5 von von NNP cord-015369-72cjogxz 5047 6 unnötigen unnötigen NN cord-015369-72cjogxz 5047 7 Nebenwirkungen Nebenwirkungen NNP cord-015369-72cjogxz 5047 8 . . . cord-015369-72cjogxz 5048 1 In in IN cord-015369-72cjogxz 5048 2 der der NNP cord-015369-72cjogxz 5048 3 Chirurgie Chirurgie NNP cord-015369-72cjogxz 5048 4 verändert verändert NNP cord-015369-72cjogxz 5048 5 sich sich NNP cord-015369-72cjogxz 5048 6 die die VB cord-015369-72cjogxz 5049 1 Logistik Logistik NNP cord-015369-72cjogxz 5049 2 von von NNP cord-015369-72cjogxz 5049 3 Diagnostik Diagnostik NNP cord-015369-72cjogxz 5049 4 und und NNP cord-015369-72cjogxz 5049 5 Therapie Therapie NNP cord-015369-72cjogxz 5049 6 grundlegend grundlegend NNP cord-015369-72cjogxz 5049 7 . . . cord-015369-72cjogxz 5050 1 Die die VB cord-015369-72cjogxz 5050 2 Schaffung Schaffung NNP cord-015369-72cjogxz 5050 3 strukturierter strukturierter NN cord-015369-72cjogxz 5050 4 Tumorbanken Tumorbanken NNP cord-015369-72cjogxz 5050 5 wird wird NNP cord-015369-72cjogxz 5050 6 notwendig notwendig NNP cord-015369-72cjogxz 5050 7 , , , cord-015369-72cjogxz 5050 8 wobei wobei NNP cord-015369-72cjogxz 5050 9 präoperative präoperative NNP cord-015369-72cjogxz 5051 1 Planung Planung NNP cord-015369-72cjogxz 5051 2 und und IN cord-015369-72cjogxz 5051 3 Operation Operation NNP cord-015369-72cjogxz 5051 4 die die VBP cord-015369-72cjogxz 5051 5 ersten ersten NNP cord-015369-72cjogxz 5051 6 wichtigen wichtigen JJ cord-015369-72cjogxz 5051 7 Schritte Schritte NNP cord-015369-72cjogxz 5051 8 darstellen darstellen NNS cord-015369-72cjogxz 5051 9 . . . cord-015369-72cjogxz 5052 1 In in IN cord-015369-72cjogxz 5052 2 Hochrisikosituationen Hochrisikosituationen NNP cord-015369-72cjogxz 5052 3 laut laut NNP cord-015369-72cjogxz 5052 4 Genexpressionsanalyse Genexpressionsanalyse NNP cord-015369-72cjogxz 5052 5 ist ist VBP cord-015369-72cjogxz 5052 6 eine eine NNP cord-015369-72cjogxz 5052 7 optimierte optimierte NN cord-015369-72cjogxz 5052 8 Lokalbehandlung Lokalbehandlung NNP cord-015369-72cjogxz 5052 9 essentiell essentiell NNP cord-015369-72cjogxz 5052 10 und und NNP cord-015369-72cjogxz 5052 11 bei bei NNP cord-015369-72cjogxz 5052 12 hoher hoher NNP cord-015369-72cjogxz 5053 1 Wahrscheinlichkeit Wahrscheinlichkeit NNP cord-015369-72cjogxz 5053 2 auf auf NN cord-015369-72cjogxz 5053 3 pathologische pathologische NN cord-015369-72cjogxz 5053 4 Komplettremission Komplettremission NNP cord-015369-72cjogxz 5053 5 eine eine JJ cord-015369-72cjogxz 5053 6 präzise präzise NN cord-015369-72cjogxz 5053 7 prätherapeutische prätherapeutische NN cord-015369-72cjogxz 5053 8 Markierung Markierung NNP cord-015369-72cjogxz 5053 9 des des NNP cord-015369-72cjogxz 5053 10 Tumors Tumors NNP cord-015369-72cjogxz 5053 11 . . . cord-015369-72cjogxz 5054 1 Die die VB cord-015369-72cjogxz 5054 2 Resultate Resultate NNP cord-015369-72cjogxz 5054 3 dieser dieser NNP cord-015369-72cjogxz 5054 4 Genexpressionsanalysen Genexpressionsanalysen NNP cord-015369-72cjogxz 5054 5 bringen bringen VBP cord-015369-72cjogxz 5054 6 eine eine NNP cord-015369-72cjogxz 5054 7 individualisierte individualisierte NNS cord-015369-72cjogxz 5054 8 adjuvante adjuvante NNP cord-015369-72cjogxz 5054 9 Chemo Chemo NNP cord-015369-72cjogxz 5054 10 - - HYPH cord-015369-72cjogxz 5054 11 und und NNP cord-015369-72cjogxz 5054 12 / / SYM cord-015369-72cjogxz 5054 13 oder oder NNP cord-015369-72cjogxz 5054 14 Hormontherapie Hormontherapie NNP cord-015369-72cjogxz 5054 15 mit mit NNP cord-015369-72cjogxz 5054 16 sich sich NNP cord-015369-72cjogxz 5054 17 . . . cord-015369-72cjogxz 5055 1 Jede(r Jede(r NNP cord-015369-72cjogxz 5055 2 ) ) -RRB- cord-015369-72cjogxz 5056 1 ChirurgIn ChirurgIn NNP cord-015369-72cjogxz 5056 2 muss muss NNP cord-015369-72cjogxz 5056 3 sich sich NNP cord-015369-72cjogxz 5056 4 mit mit NNP cord-015369-72cjogxz 5056 5 Möglichkeiten Möglichkeiten NNP cord-015369-72cjogxz 5056 6 und und XX cord-015369-72cjogxz 5057 1 Grenzen Grenzen NNP cord-015369-72cjogxz 5057 2 dieser dieser NNP cord-015369-72cjogxz 5057 3 revolutionären revolutionären NNP cord-015369-72cjogxz 5057 4 Techniken Techniken NNP cord-015369-72cjogxz 5057 5 befassen befassen NNP cord-015369-72cjogxz 5057 6 , , , cord-015369-72cjogxz 5057 7 um um UH cord-015369-72cjogxz 5057 8 weiterhin weiterhin NNP cord-015369-72cjogxz 5057 9 integrativ integrativ NNP cord-015369-72cjogxz 5057 10 i i PRP cord-015369-72cjogxz 5058 1 m m NNP cord-015369-72cjogxz 5058 2 Tumorboard Tumorboard NNP cord-015369-72cjogxz 5058 3 die die VBP cord-015369-72cjogxz 5058 4 besten besten NNP cord-015369-72cjogxz 5059 1 Entscheidungen Entscheidungen NNP cord-015369-72cjogxz 5059 2 fü fü IN cord-015369-72cjogxz 5059 3 r r NN cord-015369-72cjogxz 5059 4 unsere unsere JJ cord-015369-72cjogxz 5059 5 Patientinnen Patientinnen NNP cord-015369-72cjogxz 5059 6 treffen treffen NNP cord-015369-72cjogxz 5059 7 zu zu NNP cord-015369-72cjogxz 5059 8 können können NNP cord-015369-72cjogxz 5059 9 . . . cord-015369-72cjogxz 5060 1 Background background NN cord-015369-72cjogxz 5060 2 . . . cord-015369-72cjogxz 5061 1 Peritoneal peritoneal JJ cord-015369-72cjogxz 5061 2 carcinomatosis carcinomatosis NN cord-015369-72cjogxz 5061 3 defines define VBZ cord-015369-72cjogxz 5061 4 tumor tumor NN cord-015369-72cjogxz 5061 5 dissemination dissemination NN cord-015369-72cjogxz 5061 6 onto onto IN cord-015369-72cjogxz 5061 7 the the DT cord-015369-72cjogxz 5061 8 peritoneal peritoneal JJ cord-015369-72cjogxz 5061 9 surface surface NN cord-015369-72cjogxz 5061 10 . . . cord-015369-72cjogxz 5062 1 Hyperthermic Hyperthermic NNP cord-015369-72cjogxz 5062 2 intraperitoneal intraperitoneal JJ cord-015369-72cjogxz 5062 3 chemotherapy chemotherapy NN cord-015369-72cjogxz 5062 4 ( ( -LRB- cord-015369-72cjogxz 5062 5 HIPEC HIPEC NNP cord-015369-72cjogxz 5062 6 ) ) -RRB- cord-015369-72cjogxz 5063 1 after after IN cord-015369-72cjogxz 5063 2 cytoreductive cytoreductive NNP cord-015369-72cjogxz 5063 3 surgery surgery NN cord-015369-72cjogxz 5063 4 seems seem VBZ cord-015369-72cjogxz 5063 5 becoming become VBG cord-015369-72cjogxz 5063 6 the the DT cord-015369-72cjogxz 5063 7 standard standard JJ cord-015369-72cjogxz 5063 8 treatment treatment NN cord-015369-72cjogxz 5063 9 in in IN cord-015369-72cjogxz 5063 10 peritoneal peritoneal JJ cord-015369-72cjogxz 5063 11 carcinomatosis carcinomatosis NN cord-015369-72cjogxz 5063 12 avoiding avoid VBG cord-015369-72cjogxz 5063 13 the the DT cord-015369-72cjogxz 5063 14 risk risk NN cord-015369-72cjogxz 5063 15 of of IN cord-015369-72cjogxz 5063 16 tumor tumor NN cord-015369-72cjogxz 5063 17 cell cell NN cord-015369-72cjogxz 5063 18 inoculation inoculation NN cord-015369-72cjogxz 5063 19 after after IN cord-015369-72cjogxz 5063 20 surgery surgery NN cord-015369-72cjogxz 5063 21 . . . cord-015369-72cjogxz 5064 1 Subsequent subsequent JJ cord-015369-72cjogxz 5064 2 adhesion adhesion NN cord-015369-72cjogxz 5064 3 of of IN cord-015369-72cjogxz 5064 4 free free JJ cord-015369-72cjogxz 5064 5 tumor tumor NN cord-015369-72cjogxz 5064 6 cells cell NNS cord-015369-72cjogxz 5064 7 to to IN cord-015369-72cjogxz 5064 8 human human JJ cord-015369-72cjogxz 5064 9 peritoneal peritoneal NN cord-015369-72cjogxz 5064 10 mesothelial mesothelial JJ cord-015369-72cjogxz 5064 11 cells cell NNS cord-015369-72cjogxz 5064 12 ( ( -LRB- cord-015369-72cjogxz 5064 13 HMCs HMCs NNP cord-015369-72cjogxz 5064 14 ) ) -RRB- cord-015369-72cjogxz 5064 15 -the -the NFP cord-015369-72cjogxz 5064 16 first first JJ cord-015369-72cjogxz 5064 17 line line NN cord-015369-72cjogxz 5064 18 defense defense NN cord-015369-72cjogxz 5064 19 within within IN cord-015369-72cjogxz 5064 20 the the DT cord-015369-72cjogxz 5064 21 abdominal abdominal JJ cord-015369-72cjogxz 5064 22 cavity cavity NN cord-015369-72cjogxz 5064 23 -might -might : cord-015369-72cjogxz 5064 24 lead lead NN cord-015369-72cjogxz 5064 25 to to IN cord-015369-72cjogxz 5064 26 the the DT cord-015369-72cjogxz 5064 27 formation formation NN cord-015369-72cjogxz 5064 28 of of IN cord-015369-72cjogxz 5064 29 intraabdominal intraabdominal JJ cord-015369-72cjogxz 5064 30 metastases metastasis NNS cord-015369-72cjogxz 5064 31 . . . cord-015369-72cjogxz 5065 1 We -PRON- PRP cord-015369-72cjogxz 5065 2 investigated investigate VBD cord-015369-72cjogxz 5065 3 within within IN cord-015369-72cjogxz 5065 4 an an DT cord-015369-72cjogxz 5065 5 invitro invitro JJ cord-015369-72cjogxz 5065 6 - - HYPH cord-015369-72cjogxz 5065 7 model model VB cord-015369-72cjogxz 5065 8 the the DT cord-015369-72cjogxz 5065 9 blockage blockage NN cord-015369-72cjogxz 5065 10 of of IN cord-015369-72cjogxz 5065 11 tumor tumor NN cord-015369-72cjogxz 5065 12 cell cell NN cord-015369-72cjogxz 5065 13 adhesion adhesion NN cord-015369-72cjogxz 5065 14 by by IN cord-015369-72cjogxz 5065 15 Simvastatin Simvastatin NNP cord-015369-72cjogxz 5065 16 ( ( -LRB- cord-015369-72cjogxz 5065 17 SIM SIM NNP cord-015369-72cjogxz 5065 18 ) ) -RRB- cord-015369-72cjogxz 5065 19 , , , cord-015369-72cjogxz 5065 20 an an DT cord-015369-72cjogxz 5065 21 inhibitor inhibitor NN cord-015369-72cjogxz 5065 22 of of IN cord-015369-72cjogxz 5065 23 the the DT cord-015369-72cjogxz 5065 24 3-hydroxy-3-methylglutaryl 3-hydroxy-3-methylglutaryl CD cord-015369-72cjogxz 5066 1 ( ( -LRB- cord-015369-72cjogxz 5066 2 HMG HMG NNP cord-015369-72cjogxz 5066 3 ) ) -RRB- cord-015369-72cjogxz 5066 4 Coenzyme Coenzyme VBZ cord-015369-72cjogxz 5066 5 A a DT cord-015369-72cjogxz 5066 6 reductase reductase NN cord-015369-72cjogxz 5066 7 . . . cord-015369-72cjogxz 5067 1 Methods method NNS cord-015369-72cjogxz 5067 2 . . . cord-015369-72cjogxz 5068 1 HMCs HMCs NNP cord-015369-72cjogxz 5068 2 were be VBD cord-015369-72cjogxz 5068 3 isolated isolate VBN cord-015369-72cjogxz 5068 4 by by IN cord-015369-72cjogxz 5068 5 enzymatic enzymatic JJ cord-015369-72cjogxz 5068 6 disaggregation disaggregation NN cord-015369-72cjogxz 5068 7 from from IN cord-015369-72cjogxz 5068 8 human human JJ cord-015369-72cjogxz 5068 9 Omentum Omentum NNP cord-015369-72cjogxz 5068 10 majus majus NN cord-015369-72cjogxz 5068 11 and and CC cord-015369-72cjogxz 5068 12 expanded expand VBN cord-015369-72cjogxz 5068 13 in in IN cord-015369-72cjogxz 5068 14 vitro vitro FW cord-015369-72cjogxz 5068 15 . . . cord-015369-72cjogxz 5069 1 Confluent Confluent NNP cord-015369-72cjogxz 5069 2 HMC HMC NNP cord-015369-72cjogxz 5069 3 - - HYPH cord-015369-72cjogxz 5069 4 monolayers monolayer NNS cord-015369-72cjogxz 5069 5 were be VBD cord-015369-72cjogxz 5069 6 incubated incubate VBN cord-015369-72cjogxz 5069 7 with with IN cord-015369-72cjogxz 5069 8 fluorescent fluorescent JJ cord-015369-72cjogxz 5069 9 labelled label VBN cord-015369-72cjogxz 5069 10 tumor tumor NN cord-015369-72cjogxz 5069 11 cells cell NNS cord-015369-72cjogxz 5069 12 in in IN cord-015369-72cjogxz 5069 13 the the DT cord-015369-72cjogxz 5069 14 presence presence NN cord-015369-72cjogxz 5069 15 or or CC cord-015369-72cjogxz 5069 16 absence absence NN cord-015369-72cjogxz 5069 17 of of IN cord-015369-72cjogxz 5069 18 SIM SIM NNP cord-015369-72cjogxz 5069 19 . . . cord-015369-72cjogxz 5070 1 In in IN cord-015369-72cjogxz 5070 2 time time NN cord-015369-72cjogxz 5070 3 course course NN cord-015369-72cjogxz 5070 4 experiments experiment NNS cord-015369-72cjogxz 5070 5 , , , cord-015369-72cjogxz 5070 6 adhesion adhesion NN cord-015369-72cjogxz 5070 7 of of IN cord-015369-72cjogxz 5070 8 SKOV-3 SKOV-3 NNP cord-015369-72cjogxz 5070 9 ( ( -LRB- cord-015369-72cjogxz 5070 10 ovarian ovarian JJ cord-015369-72cjogxz 5070 11 tumor tumor NN cord-015369-72cjogxz 5070 12 ) ) -RRB- cord-015369-72cjogxz 5070 13 and and CC cord-015369-72cjogxz 5070 14 HT-29 HT-29 NNP cord-015369-72cjogxz 5070 15 ( ( -LRB- cord-015369-72cjogxz 5070 16 colorectal colorectal JJ cord-015369-72cjogxz 5070 17 tumor tumor NN cord-015369-72cjogxz 5070 18 ) ) -RRB- cord-015369-72cjogxz 5070 19 cells cell NNS cord-015369-72cjogxz 5070 20 to to IN cord-015369-72cjogxz 5070 21 HMCs hmc NNS cord-015369-72cjogxz 5070 22 were be VBD cord-015369-72cjogxz 5070 23 determined determine VBN cord-015369-72cjogxz 5070 24 either either CC cord-015369-72cjogxz 5070 25 by by IN cord-015369-72cjogxz 5070 26 fluorescence fluorescence NN cord-015369-72cjogxz 5070 27 microscopy microscopy NNS cord-015369-72cjogxz 5070 28 or or CC cord-015369-72cjogxz 5070 29 reader reader NN cord-015369-72cjogxz 5070 30 . . . cord-015369-72cjogxz 5071 1 Results result NNS cord-015369-72cjogxz 5071 2 . . . cord-015369-72cjogxz 5072 1 Simvastatin Simvastatin NNP cord-015369-72cjogxz 5072 2 reduced reduce VBD cord-015369-72cjogxz 5072 3 the the DT cord-015369-72cjogxz 5072 4 number number NN cord-015369-72cjogxz 5072 5 of of IN cord-015369-72cjogxz 5072 6 adherent adherent JJ cord-015369-72cjogxz 5072 7 SKOV-3 SKOV-3 NNP cord-015369-72cjogxz 5072 8 and and CC cord-015369-72cjogxz 5072 9 HT29 HT29 NNP cord-015369-72cjogxz 5072 10 cells cell NNS cord-015369-72cjogxz 5072 11 to to IN cord-015369-72cjogxz 5072 12 HMCs HMCs NNP cord-015369-72cjogxz 5072 13 significantly significantly RB cord-015369-72cjogxz 5072 14 . . . cord-015369-72cjogxz 5073 1 At at IN cord-015369-72cjogxz 5073 2 concentrations concentration NNS cord-015369-72cjogxz 5073 3 ranging range VBG cord-015369-72cjogxz 5073 4 from from IN cord-015369-72cjogxz 5073 5 2.5 2.5 CD cord-015369-72cjogxz 5073 6 to to TO cord-015369-72cjogxz 5073 7 10 10 CD cord-015369-72cjogxz 5073 8 mM mm CD cord-015369-72cjogxz 5073 9 , , , cord-015369-72cjogxz 5073 10 Simvastatin Simvastatin NNP cord-015369-72cjogxz 5073 11 reduced reduce VBD cord-015369-72cjogxz 5073 12 the the DT cord-015369-72cjogxz 5073 13 adherence adherence NN cord-015369-72cjogxz 5073 14 of of IN cord-015369-72cjogxz 5073 15 tumor tumor NN cord-015369-72cjogxz 5073 16 cells cell NNS cord-015369-72cjogxz 5073 17 to to IN cord-015369-72cjogxz 5073 18 HMCs hmc NNS cord-015369-72cjogxz 5073 19 up up IN cord-015369-72cjogxz 5073 20 to to TO cord-015369-72cjogxz 5073 21 60 60 CD cord-015369-72cjogxz 5073 22 % % NN cord-015369-72cjogxz 5073 23 . . . cord-015369-72cjogxz 5074 1 Conclusions conclusion NNS cord-015369-72cjogxz 5074 2 . . . cord-015369-72cjogxz 5075 1 Our -PRON- PRP$ cord-015369-72cjogxz 5075 2 findings finding NNS cord-015369-72cjogxz 5075 3 suggest suggest VBP cord-015369-72cjogxz 5075 4 that that IN cord-015369-72cjogxz 5075 5 Simvastatin Simvastatin NNP cord-015369-72cjogxz 5075 6 might may MD cord-015369-72cjogxz 5075 7 be be VB cord-015369-72cjogxz 5075 8 a a DT cord-015369-72cjogxz 5075 9 novel novel JJ cord-015369-72cjogxz 5075 10 therapeutic therapeutic JJ cord-015369-72cjogxz 5075 11 approach approach NN cord-015369-72cjogxz 5075 12 in in IN cord-015369-72cjogxz 5075 13 order order NN cord-015369-72cjogxz 5075 14 to to TO cord-015369-72cjogxz 5075 15 reduce reduce VB cord-015369-72cjogxz 5075 16 the the DT cord-015369-72cjogxz 5075 17 risk risk NN cord-015369-72cjogxz 5075 18 of of IN cord-015369-72cjogxz 5075 19 peritoneal peritoneal JJ cord-015369-72cjogxz 5075 20 metastasis metastasis NN cord-015369-72cjogxz 5075 21 due due JJ cord-015369-72cjogxz 5075 22 to to IN cord-015369-72cjogxz 5075 23 tumor tumor NN cord-015369-72cjogxz 5075 24 cell cell NN cord-015369-72cjogxz 5075 25 dissemination dissemination NN cord-015369-72cjogxz 5075 26 during during IN cord-015369-72cjogxz 5075 27 cytoreductive cytoreductive JJ cord-015369-72cjogxz 5075 28 surgery surgery NN cord-015369-72cjogxz 5075 29 . . . cord-015369-72cjogxz 5076 1 Further further JJ cord-015369-72cjogxz 5076 2 investigations investigation NNS cord-015369-72cjogxz 5076 3 also also RB cord-015369-72cjogxz 5076 4 have have VBP cord-015369-72cjogxz 5076 5 to to TO cord-015369-72cjogxz 5076 6 include include VB cord-015369-72cjogxz 5076 7 the the DT cord-015369-72cjogxz 5076 8 mechanism mechanism NN cord-015369-72cjogxz 5076 9 on on IN cord-015369-72cjogxz 5076 10 the the DT cord-015369-72cjogxz 5076 11 molecular molecular JJ cord-015369-72cjogxz 5076 12 level level NN cord-015369-72cjogxz 5076 13 . . . cord-015369-72cjogxz 5077 1 Einleitung Einleitung NNP cord-015369-72cjogxz 5077 2 HER-2 HER-2 NNP cord-015369-72cjogxz 5077 3 / / SYM cord-015369-72cjogxz 5077 4 neu neu NNP cord-015369-72cjogxz 5077 5 ( ( -LRB- cord-015369-72cjogxz 5077 6 c c NNP cord-015369-72cjogxz 5077 7 - - : cord-015369-72cjogxz 5077 8 erbB2 erbb2 ADD cord-015369-72cjogxz 5077 9 ) ) -RRB- cord-015369-72cjogxz 5078 1 Ü Ü NNP cord-015369-72cjogxz 5078 2 berexpression berexpression NNP cord-015369-72cjogxz 5079 1 ist ist NNP cord-015369-72cjogxz 5079 2 assoziiert assoziiert NNP cord-015369-72cjogxz 5079 3 mit mit NNP cord-015369-72cjogxz 5079 4 einem einem NNP cord-015369-72cjogxz 5079 5 höheren höheren NNP cord-015369-72cjogxz 5079 6 angiogenetischen angiogenetischen , cord-015369-72cjogxz 5079 7 Potential Potential NNP cord-015369-72cjogxz 5079 8 und und XX cord-015369-72cjogxz 5079 9 einer einer NNP cord-015369-72cjogxz 5080 1 erhöhten erhöhten NNP cord-015369-72cjogxz 5080 2 Expression Expression NNP cord-015369-72cjogxz 5080 3 des des FW cord-015369-72cjogxz 5080 4 vaskulären vaskulären NN cord-015369-72cjogxz 5081 1 Wachstumsfaktors Wachstumsfaktors NNP cord-015369-72cjogxz 5081 2 VEGF VEGF NNP cord-015369-72cjogxz 5081 3 beim beim NNP cord-015369-72cjogxz 5081 4 Mammakarzinom Mammakarzinom NNP cord-015369-72cjogxz 5081 5 . . . cord-015369-72cjogxz 5082 1 Vorklinische Vorklinische NNP cord-015369-72cjogxz 5082 2 Studien Studien NNP cord-015369-72cjogxz 5082 3 haben haben NNP cord-015369-72cjogxz 5082 4 gezeigt gezeigt NNP cord-015369-72cjogxz 5082 5 , , , cord-015369-72cjogxz 5083 1 dass dass NNP cord-015369-72cjogxz 5083 2 HER-2 HER-2 NNP cord-015369-72cjogxz 5083 3 / / SYM cord-015369-72cjogxz 5083 4 neu neu NNP cord-015369-72cjogxz 5083 5 eventuell eventuell FW cord-015369-72cjogxz 5083 6 eine eine NNP cord-015369-72cjogxz 5084 1 zusätzliche zusätzliche NNP cord-015369-72cjogxz 5084 2 Rolle Rolle NNP cord-015369-72cjogxz 5084 3 bei bei NNP cord-015369-72cjogxz 5084 4 der der NNP cord-015369-72cjogxz 5084 5 Regulierung Regulierung NNP cord-015369-72cjogxz 5084 6 der der NNP cord-015369-72cjogxz 5084 7 Expression Expression NNP cord-015369-72cjogxz 5084 8 des des FW cord-015369-72cjogxz 5084 9 lymphatischen lymphatischen NNP cord-015369-72cjogxz 5084 10 Wachstumsfaktors Wachstumsfaktors NNP cord-015369-72cjogxz 5084 11 ( ( -LRB- cord-015369-72cjogxz 5084 12 VEGF VEGF NNP cord-015369-72cjogxz 5084 13 - - HYPH cord-015369-72cjogxz 5084 14 C C NNP cord-015369-72cjogxz 5084 15 ) ) -RRB- cord-015369-72cjogxz 5084 16 und und NNP cord-015369-72cjogxz 5084 17 damit damit NNP cord-015369-72cjogxz 5084 18 bei bei NNP cord-015369-72cjogxz 5084 19 der der NNP cord-015369-72cjogxz 5084 20 lymphatischen lymphatischen NNP cord-015369-72cjogxz 5084 21 Metastasierung Metastasierung NNP cord-015369-72cjogxz 5084 22 spielt spielt NNP cord-015369-72cjogxz 5084 23 . . . cord-015369-72cjogxz 5085 1 Sinn Sinn NNP cord-015369-72cjogxz 5085 2 dieser dieser NNP cord-015369-72cjogxz 5085 3 Studie Studie NNP cord-015369-72cjogxz 5085 4 , , , cord-015369-72cjogxz 5085 5 war war NN cord-015369-72cjogxz 5085 6 es es XX cord-015369-72cjogxz 5085 7 diesen diesen NNP cord-015369-72cjogxz 5085 8 Zusammenhang Zusammenhang NNP cord-015369-72cjogxz 5085 9 zwischen zwischen NNP cord-015369-72cjogxz 5085 10 der der NNP cord-015369-72cjogxz 5085 11 HER-2 HER-2 NNP cord-015369-72cjogxz 5085 12 / / SYM cord-015369-72cjogxz 5085 13 neu neu NNP cord-015369-72cjogxz 5085 14 Expression Expression NNP cord-015369-72cjogxz 5085 15 , , , cord-015369-72cjogxz 5085 16 der der NNP cord-015369-72cjogxz 5085 17 Expression expression NN cord-015369-72cjogxz 5085 18 des des NN cord-015369-72cjogxz 5086 1 lymphatischen lymphatischen NNP cord-015369-72cjogxz 5086 2 Wachstumsfaktors Wachstumsfaktors NNP cord-015369-72cjogxz 5086 3 VEGF VEGF NNP cord-015369-72cjogxz 5086 4 - - HYPH cord-015369-72cjogxz 5086 5 C C NNP cord-015369-72cjogxz 5086 6 , , , cord-015369-72cjogxz 5086 7 dem dem NNP cord-015369-72cjogxz 5086 8 Ausmaß Ausmaß NNP cord-015369-72cjogxz 5086 9 des des FW cord-015369-72cjogxz 5086 10 lymphangiogenetischen lymphangiogenetischen NNP cord-015369-72cjogxz 5086 11 Potentials Potentials NNPS cord-015369-72cjogxz 5086 12 ( ( -LRB- cord-015369-72cjogxz 5086 13 LMVD LMVD NNP cord-015369-72cjogxz 5086 14 ) ) -RRB- cord-015369-72cjogxz 5086 15 sowie sowie NNP cord-015369-72cjogxz 5086 16 der der NNP cord-015369-72cjogxz 5086 17 spezifischen spezifischen NNP cord-015369-72cjogxz 5086 18 lymphogenen lymphogenen NNP cord-015369-72cjogxz 5086 19 Invasion Invasion NNP cord-015369-72cjogxz 5086 20 ( ( -LRB- cord-015369-72cjogxz 5086 21 LVI LVI NNP cord-015369-72cjogxz 5086 22 ) ) -RRB- cord-015369-72cjogxz 5086 23 in in IN cord-015369-72cjogxz 5086 24 einem einem NNP cord-015369-72cjogxz 5086 25 Kollektiv Kollektiv NNP cord-015369-72cjogxz 5086 26 von von NNP cord-015369-72cjogxz 5086 27 150 150 CD cord-015369-72cjogxz 5087 1 lymphknoten lymphknoten NNP cord-015369-72cjogxz 5087 2 - - HYPH cord-015369-72cjogxz 5087 3 positiven positiven NNP cord-015369-72cjogxz 5087 4 Mammakarzinomen Mammakarzinomen NNP cord-015369-72cjogxz 5087 5 zu zu NNP cord-015369-72cjogxz 5087 6 ü ü NNP cord-015369-72cjogxz 5087 7 berprü berprü NNP cord-015369-72cjogxz 5087 8 fen fen NNP cord-015369-72cjogxz 5087 9 . . . cord-015369-72cjogxz 5088 1 Methodik Methodik NNP cord-015369-72cjogxz 5088 2 Immunhistochemie Immunhistochemie NNP cord-015369-72cjogxz 5088 3 und und IN cord-015369-72cjogxz 5089 1 Insitu Insitu NNP cord-015369-72cjogxz 5089 2 - - HYPH cord-015369-72cjogxz 5089 3 Hybridisierung Hybridisierung NNP cord-015369-72cjogxz 5090 1 fü fü IN cord-015369-72cjogxz 5091 1 r r LS cord-015369-72cjogxz 5091 2 VEGF VEGF NNP cord-015369-72cjogxz 5091 3 - - HYPH cord-015369-72cjogxz 5091 4 C C NNP cord-015369-72cjogxz 5092 1 , , , cord-015369-72cjogxz 5092 2 den den NNP cord-015369-72cjogxz 5092 3 lymphatischen lymphatischen NNP cord-015369-72cjogxz 5092 4 Endothelzellmarker Endothelzellmarker NNP cord-015369-72cjogxz 5092 5 Podoplanin Podoplanin NNP cord-015369-72cjogxz 5092 6 sowie sowie XX cord-015369-72cjogxz 5093 1 fü fü IN cord-015369-72cjogxz 5094 1 r r NNP cord-015369-72cjogxz 5094 2 HER-2 HER-2 NNP cord-015369-72cjogxz 5094 3 / / SYM cord-015369-72cjogxz 5094 4 neu neu NNP cord-015369-72cjogxz 5094 5 wurden wurden NNP cord-015369-72cjogxz 5095 1 durchgefü durchgefü NNP cord-015369-72cjogxz 5095 2 hrt hrt NNP cord-015369-72cjogxz 5095 3 . . . cord-015369-72cjogxz 5096 1 Weiters weiter NNS cord-015369-72cjogxz 5096 2 wurde wurde VBD cord-015369-72cjogxz 5096 3 eine eine NNP cord-015369-72cjogxz 5097 1 HER-2 HER-2 NNP cord-015369-72cjogxz 5097 2 / / SYM cord-015369-72cjogxz 5097 3 neu neu NNP cord-015369-72cjogxz 5097 4 FISH FISH NNP cord-015369-72cjogxz 5098 1 Analyse Analyse NNP cord-015369-72cjogxz 5098 2 bei bei NNP cord-015369-72cjogxz 5098 3 allen allen NNP cord-015369-72cjogxz 5098 4 150 150 CD cord-015369-72cjogxz 5098 5 Karzinompräparaten Karzinompräparaten NNP cord-015369-72cjogxz 5098 6 angewendet angewendet NNP cord-015369-72cjogxz 5098 7 . . . cord-015369-72cjogxz 5099 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 5099 2 LMVD LMVD NNP cord-015369-72cjogxz 5099 3 korrelierte korrelierte NNP cord-015369-72cjogxz 5099 4 signifikant signifikant NNP cord-015369-72cjogxz 5099 5 mit mit NNP cord-015369-72cjogxz 5099 6 LVI LVI NNP cord-015369-72cjogxz 5099 7 ( ( -LRB- cord-015369-72cjogxz 5099 8 p p NN cord-015369-72cjogxz 5099 9 0.005 0.005 CD cord-015369-72cjogxz 5099 10 ) ) -RRB- cord-015369-72cjogxz 5100 1 und und NNP cord-015369-72cjogxz 5101 1 der der NNP cord-015369-72cjogxz 5101 2 VEGF VEGF NNP cord-015369-72cjogxz 5101 3 - - HYPH cord-015369-72cjogxz 5101 4 C C NNP cord-015369-72cjogxz 5101 5 Expression expression NN cord-015369-72cjogxz 5101 6 ( ( -LRB- cord-015369-72cjogxz 5101 7 p p NN cord-015369-72cjogxz 5101 8 ¼ ¼ CD cord-015369-72cjogxz 5101 9 0.014 0.014 CD cord-015369-72cjogxz 5101 10 ) ) -RRB- cord-015369-72cjogxz 5101 11 . . . cord-015369-72cjogxz 5102 1 Weiters Weiters NNP cord-015369-72cjogxz 5102 2 konnte konnte NNP cord-015369-72cjogxz 5103 1 eine eine NNP cord-015369-72cjogxz 5103 2 positive positive JJ cord-015369-72cjogxz 5103 3 , , , cord-015369-72cjogxz 5103 4 statistisch statistisch NNP cord-015369-72cjogxz 5103 5 signifikante signifikante NNP cord-015369-72cjogxz 5103 6 Korrelation Korrelation NNP cord-015369-72cjogxz 5103 7 zwischen zwischen NNP cord-015369-72cjogxz 5103 8 der der NNP cord-015369-72cjogxz 5103 9 HER-2 HER-2 NNP cord-015369-72cjogxz 5103 10 / / SYM cord-015369-72cjogxz 5103 11 neu neu NNP cord-015369-72cjogxz 5103 12 - - HYPH cord-015369-72cjogxz 5103 13 und und NNP cord-015369-72cjogxz 5103 14 VEGF VEGF NNP cord-015369-72cjogxz 5103 15 - - HYPH cord-015369-72cjogxz 5103 16 C C NNP cord-015369-72cjogxz 5103 17 Proteinexpression Proteinexpression NNP cord-015369-72cjogxz 5103 18 gefunden gefunden NN cord-015369-72cjogxz 5103 19 werden werden NNP cord-015369-72cjogxz 5104 1 ( ( -LRB- cord-015369-72cjogxz 5104 2 p p NN cord-015369-72cjogxz 5104 3 ¼ ¼ CD cord-015369-72cjogxz 5104 4 0.015 0.015 CD cord-015369-72cjogxz 5104 5 ) ) -RRB- cord-015369-72cjogxz 5104 6 . . . cord-015369-72cjogxz 5105 1 Patienten Patienten NNP cord-015369-72cjogxz 5105 2 , , , cord-015369-72cjogxz 5105 3 deren deren NNP cord-015369-72cjogxz 5105 4 Tumore Tumore NNP cord-015369-72cjogxz 5106 1 eine eine NNP cord-015369-72cjogxz 5106 2 höhere höhere NNP cord-015369-72cjogxz 5107 1 HER-2 HER-2 NNP cord-015369-72cjogxz 5107 2 / / SYM cord-015369-72cjogxz 5107 3 neu neu NNP cord-015369-72cjogxz 5107 4 Expression Expression NNP cord-015369-72cjogxz 5107 5 aufwiesen aufwiesen NNP cord-015369-72cjogxz 5107 6 , , , cord-015369-72cjogxz 5108 1 exprimierten exprimierten NNP cord-015369-72cjogxz 5108 2 auch auch NNP cord-015369-72cjogxz 5108 3 signifikant signifikant NNP cord-015369-72cjogxz 5108 4 mehr mehr NNP cord-015369-72cjogxz 5108 5 VEGF VEGF NNP cord-015369-72cjogxz 5108 6 - - HYPH cord-015369-72cjogxz 5108 7 C C NNP cord-015369-72cjogxz 5109 1 und und NNP cord-015369-72cjogxz 5109 2 wiesen wiesen NNP cord-015369-72cjogxz 5109 3 ein ein NNP cord-015369-72cjogxz 5109 4 höheres höheres NNP cord-015369-72cjogxz 5109 5 lymphangiogenetisches lymphangiogenetisches NNP cord-015369-72cjogxz 5110 1 Potential potential JJ cord-015369-72cjogxz 5110 2 ( ( -LRB- cord-015369-72cjogxz 5110 3 LMVD LMVD NNP cord-015369-72cjogxz 5110 4 ) ) -RRB- cord-015369-72cjogxz 5110 5 auf auf NNP cord-015369-72cjogxz 5110 6 . . . cord-015369-72cjogxz 5111 1 Diskussion Diskussion NNP cord-015369-72cjogxz 5111 2 Unsere Unsere NNP cord-015369-72cjogxz 5112 1 Daten Daten NNP cord-015369-72cjogxz 5113 1 geben geben NNP cord-015369-72cjogxz 5113 2 den den NNP cord-015369-72cjogxz 5113 3 ersten ersten NNP cord-015369-72cjogxz 5114 1 Hinweis Hinweis NNP cord-015369-72cjogxz 5114 2 auf auf NNP cord-015369-72cjogxz 5114 3 einen einen NNP cord-015369-72cjogxz 5114 4 klinisch klinisch NNP cord-015369-72cjogxz 5114 5 relevanten relevanten NNP cord-015369-72cjogxz 5114 6 Zusammenhang Zusammenhang NNP cord-015369-72cjogxz 5114 7 zwischen zwischen NNP cord-015369-72cjogxz 5114 8 VEGF VEGF NNP cord-015369-72cjogxz 5114 9 - - HYPH cord-015369-72cjogxz 5114 10 C C NNP cord-015369-72cjogxz 5114 11 und und NN cord-015369-72cjogxz 5115 1 HER-2 HER-2 NNP cord-015369-72cjogxz 5115 2 / / SYM cord-015369-72cjogxz 5115 3 neu neu NNP cord-015369-72cjogxz 5115 4 beim beim NNP cord-015369-72cjogxz 5116 1 lymphknotenpositiven lymphknotenpositiven NNP cord-015369-72cjogxz 5116 2 Brustkrebs Brustkrebs NNP cord-015369-72cjogxz 5116 3 und und IN cord-015369-72cjogxz 5116 4 damit damit NNP cord-015369-72cjogxz 5116 5 einen einen NNP cord-015369-72cjogxz 5116 6 direkten direkten NNP cord-015369-72cjogxz 5116 7 Zusammenhang Zusammenhang NNP cord-015369-72cjogxz 5116 8 zwischen zwischen NNP cord-015369-72cjogxz 5116 9 dem dem NNP cord-015369-72cjogxz 5116 10 Ausmaß Ausmaß NNP cord-015369-72cjogxz 5116 11 einer einer NNP cord-015369-72cjogxz 5117 1 HER-2 HER-2 NNP cord-015369-72cjogxz 5117 2 / / SYM cord-015369-72cjogxz 5117 3 neu neu NNP cord-015369-72cjogxz 5117 4 Expression expression NN cord-015369-72cjogxz 5117 5 und und XX cord-015369-72cjogxz 5118 1 dem dem NNP cord-015369-72cjogxz 5118 2 lymphatischen lymphatischen NNP cord-015369-72cjogxz 5118 3 Metastasierungspotentials Metastasierungspotentials NNP cord-015369-72cjogxz 5118 4 beim beim NNP cord-015369-72cjogxz 5118 5 Mammakarzinom Mammakarzinom NNP cord-015369-72cjogxz 5118 6 ab ab NNP cord-015369-72cjogxz 5118 7 . . . cord-015369-72cjogxz 5119 1 Diese Diese NNP cord-015369-72cjogxz 5120 1 Daten Daten NNP cord-015369-72cjogxz 5120 2 unterstü unterstü NN cord-015369-72cjogxz 5121 1 tzen tzen NNS cord-015369-72cjogxz 5121 2 die die VBP cord-015369-72cjogxz 5121 3 Bedeutung Bedeutung NNP cord-015369-72cjogxz 5121 4 des des NNP cord-015369-72cjogxz 5121 5 HER-2 HER-2 NNP cord-015369-72cjogxz 5121 6 / / SYM cord-015369-72cjogxz 5121 7 neus neus NNP cord-015369-72cjogxz 5121 8 als als NNP cord-015369-72cjogxz 5121 9 Konduktor Konduktor NNP cord-015369-72cjogxz 5121 10 eines eines NNPS cord-015369-72cjogxz 5122 1 aggressiven aggressiven NNP cord-015369-72cjogxz 5123 1 Phenotyps Phenotyps NNP cord-015369-72cjogxz 5123 2 beim beim NNP cord-015369-72cjogxz 5123 3 Mammakarzinom Mammakarzinom NNP cord-015369-72cjogxz 5123 4 und und IN cord-015369-72cjogxz 5123 5 liefern liefern NNP cord-015369-72cjogxz 5123 6 mögliche mögliche NNP cord-015369-72cjogxz 5124 1 Hinweise Hinweise NNP cord-015369-72cjogxz 5125 1 auf auf NNP cord-015369-72cjogxz 5126 1 die die VB cord-015369-72cjogxz 5127 1 Wirkungsweise Wirkungsweise NNP cord-015369-72cjogxz 5127 2 assoziierter assoziierter NNP cord-015369-72cjogxz 5127 3 Therapien Therapien NNP cord-015369-72cjogxz 5128 1 wie wie NNP cord-015369-72cjogxz 5128 2 dem dem NNP cord-015369-72cjogxz 5128 3 trastuzumab trastuzumab NNPS cord-015369-72cjogxz 5128 4 ( ( -LRB- cord-015369-72cjogxz 5128 5 Herceptin Herceptin NNP cord-015369-72cjogxz 5128 6 ) ) -RRB- cord-015369-72cjogxz 5128 7 . . . cord-015369-72cjogxz 5129 1 Background background NN cord-015369-72cjogxz 5129 2 . . . cord-015369-72cjogxz 5130 1 GERD GERD NNP cord-015369-72cjogxz 5130 2 affects affect VBZ cord-015369-72cjogxz 5130 3 up up IN cord-015369-72cjogxz 5130 4 to to TO cord-015369-72cjogxz 5130 5 40 40 CD cord-015369-72cjogxz 5130 6 % % NN cord-015369-72cjogxz 5130 7 of of IN cord-015369-72cjogxz 5130 8 the the DT cord-015369-72cjogxz 5130 9 population population NN cord-015369-72cjogxz 5130 10 in in IN cord-015369-72cjogxz 5130 11 the the DT cord-015369-72cjogxz 5130 12 western western JJ cord-015369-72cjogxz 5130 13 world world NN cord-015369-72cjogxz 5130 14 . . . cord-015369-72cjogxz 5131 1 Despite despite IN cord-015369-72cjogxz 5131 2 morphological morphological JJ cord-015369-72cjogxz 5131 3 changes change NNS cord-015369-72cjogxz 5131 4 in in IN cord-015369-72cjogxz 5131 5 the the DT cord-015369-72cjogxz 5131 6 esophagus esophagus NN cord-015369-72cjogxz 5131 7 , , , cord-015369-72cjogxz 5131 8 GERD GERD NNP cord-015369-72cjogxz 5131 9 causes cause VBZ cord-015369-72cjogxz 5131 10 significant significant JJ cord-015369-72cjogxz 5131 11 impairment impairment NN cord-015369-72cjogxz 5131 12 of of IN cord-015369-72cjogxz 5131 13 the the DT cord-015369-72cjogxz 5131 14 quality quality NN cord-015369-72cjogxz 5131 15 of of IN cord-015369-72cjogxz 5131 16 life life NN cord-015369-72cjogxz 5131 17 ( ( -LRB- cord-015369-72cjogxz 5131 18 QOL QOL NNP cord-015369-72cjogxz 5131 19 ) ) -RRB- cord-015369-72cjogxz 5131 20 . . . cord-015369-72cjogxz 5132 1 We -PRON- PRP cord-015369-72cjogxz 5132 2 aimed aim VBD cord-015369-72cjogxz 5132 3 to to TO cord-015369-72cjogxz 5132 4 identify identify VB cord-015369-72cjogxz 5132 5 the the DT cord-015369-72cjogxz 5132 6 QOL QOL NNP cord-015369-72cjogxz 5132 7 in in IN cord-015369-72cjogxz 5132 8 patients patient NNS cord-015369-72cjogxz 5132 9 with with IN cord-015369-72cjogxz 5132 10 GERD GERD NNP cord-015369-72cjogxz 5132 11 and and CC cord-015369-72cjogxz 5132 12 to to TO cord-015369-72cjogxz 5132 13 assess assess VB cord-015369-72cjogxz 5132 14 the the DT cord-015369-72cjogxz 5132 15 midterm midterm NN cord-015369-72cjogxz 5132 16 effect effect NN cord-015369-72cjogxz 5132 17 of of IN cord-015369-72cjogxz 5132 18 treatment treatment NN cord-015369-72cjogxz 5132 19 on on IN cord-015369-72cjogxz 5132 20 the the DT cord-015369-72cjogxz 5132 21 QOL QOL NNP cord-015369-72cjogxz 5132 22 - - HYPH cord-015369-72cjogxz 5132 23 scores score NNS cord-015369-72cjogxz 5132 24 . . . cord-015369-72cjogxz 5133 1 In in IN cord-015369-72cjogxz 5133 2 addition addition NN cord-015369-72cjogxz 5133 3 we -PRON- PRP cord-015369-72cjogxz 5133 4 aimed aim VBD cord-015369-72cjogxz 5133 5 to to TO cord-015369-72cjogxz 5133 6 compare compare VB cord-015369-72cjogxz 5133 7 data datum NNS cord-015369-72cjogxz 5133 8 obtained obtain VBN cord-015369-72cjogxz 5133 9 by by IN cord-015369-72cjogxz 5133 10 esophageal esophageal JJ cord-015369-72cjogxz 5133 11 function function NN cord-015369-72cjogxz 5133 12 tests test NNS cord-015369-72cjogxz 5133 13 ( ( -LRB- cord-015369-72cjogxz 5133 14 EFT EFT NNP cord-015369-72cjogxz 5133 15 ) ) -RRB- cord-015369-72cjogxz 5133 16 between between IN cord-015369-72cjogxz 5133 17 the the DT cord-015369-72cjogxz 5133 18 two two CD cord-015369-72cjogxz 5133 19 groups group NNS cord-015369-72cjogxz 5133 20 and and CC cord-015369-72cjogxz 5133 21 with with IN cord-015369-72cjogxz 5133 22 pre pre JJ cord-015369-72cjogxz 5133 23 - - JJ cord-015369-72cjogxz 5133 24 interventional interventional JJ cord-015369-72cjogxz 5133 25 QOL qol NN cord-015369-72cjogxz 5133 26 - - HYPH cord-015369-72cjogxz 5133 27 scores score NNS cord-015369-72cjogxz 5133 28 . . . cord-015369-72cjogxz 5134 1 Methods method NNS cord-015369-72cjogxz 5134 2 . . . cord-015369-72cjogxz 5135 1 Ninty ninty CD cord-015369-72cjogxz 5135 2 - - HYPH cord-015369-72cjogxz 5135 3 seven seven CD cord-015369-72cjogxz 5135 4 patients patient NNS cord-015369-72cjogxz 5135 5 with with IN cord-015369-72cjogxz 5135 6 GERD GERD NNP cord-015369-72cjogxz 5135 7 symptoms symptom NNS cord-015369-72cjogxz 5135 8 underwent undergo VBD cord-015369-72cjogxz 5135 9 esophageal esophageal JJ cord-015369-72cjogxz 5135 10 manometry manometry NN cord-015369-72cjogxz 5135 11 and and CC cord-015369-72cjogxz 5135 12 24 24 CD cord-015369-72cjogxz 5135 13 h h NN cord-015369-72cjogxz 5135 14 pH ph NN cord-015369-72cjogxz 5135 15 - - HYPH cord-015369-72cjogxz 5135 16 monitoring monitoring NN cord-015369-72cjogxz 5135 17 or or CC cord-015369-72cjogxz 5135 18 combined combine VBN cord-015369-72cjogxz 5135 19 pH ph NN cord-015369-72cjogxz 5135 20 - - HYPH cord-015369-72cjogxz 5135 21 multichannel multichannel JJ cord-015369-72cjogxz 5135 22 - - HYPH cord-015369-72cjogxz 5135 23 intraluminal intraluminal JJ cord-015369-72cjogxz 5135 24 - - HYPH cord-015369-72cjogxz 5135 25 impedance impedance NN cord-015369-72cjogxz 5135 26 . . . cord-015369-72cjogxz 5136 1 The the DT cord-015369-72cjogxz 5136 2 patients patient NNS cord-015369-72cjogxz 5136 3 received receive VBD cord-015369-72cjogxz 5136 4 either either CC cord-015369-72cjogxz 5136 5 medical medical JJ cord-015369-72cjogxz 5136 6 or or CC cord-015369-72cjogxz 5136 7 surgical surgical JJ cord-015369-72cjogxz 5136 8 treatment treatment NN cord-015369-72cjogxz 5136 9 . . . cord-015369-72cjogxz 5137 1 QOL QOL NNP cord-015369-72cjogxz 5137 2 was be VBD cord-015369-72cjogxz 5137 3 assessed assess VBN cord-015369-72cjogxz 5137 4 using use VBG cord-015369-72cjogxz 5137 5 the the DT cord-015369-72cjogxz 5137 6 German german JJ cord-015369-72cjogxz 5137 7 version version NN cord-015369-72cjogxz 5137 8 of of IN cord-015369-72cjogxz 5137 9 the the DT cord-015369-72cjogxz 5137 10 SF SF NNP cord-015369-72cjogxz 5137 11 36 36 CD cord-015369-72cjogxz 5137 12 . . . cord-015369-72cjogxz 5138 1 Results result NNS cord-015369-72cjogxz 5138 2 . . . cord-015369-72cjogxz 5139 1 Significantly significantly RB cord-015369-72cjogxz 5139 2 lower low JJR cord-015369-72cjogxz 5139 3 pre pre JJ cord-015369-72cjogxz 5139 4 - - JJ cord-015369-72cjogxz 5139 5 interventional interventional JJ cord-015369-72cjogxz 5139 6 SF SF NNP cord-015369-72cjogxz 5139 7 36 36 CD cord-015369-72cjogxz 5139 8 scores score NNS cord-015369-72cjogxz 5139 9 were be VBD cord-015369-72cjogxz 5139 10 found find VBN cord-015369-72cjogxz 5139 11 for for IN cord-015369-72cjogxz 5139 12 3 3 CD cord-015369-72cjogxz 5139 13 of of IN cord-015369-72cjogxz 5139 14 the the DT cord-015369-72cjogxz 5139 15 8 8 CD cord-015369-72cjogxz 5139 16 dimensions dimension NNS cord-015369-72cjogxz 5139 17 compared compare VBN cord-015369-72cjogxz 5139 18 with with IN cord-015369-72cjogxz 5139 19 the the DT cord-015369-72cjogxz 5139 20 published publish VBN cord-015369-72cjogxz 5139 21 normative normative JJ cord-015369-72cjogxz 5139 22 data datum NNS cord-015369-72cjogxz 5139 23 for for IN cord-015369-72cjogxz 5139 24 the the DT cord-015369-72cjogxz 5139 25 general general JJ cord-015369-72cjogxz 5139 26 US US NNP cord-015369-72cjogxz 5139 27 population population NN cord-015369-72cjogxz 5139 28 . . . cord-015369-72cjogxz 5140 1 Conservative conservative JJ cord-015369-72cjogxz 5140 2 treatment treatment NN cord-015369-72cjogxz 5140 3 could could MD cord-015369-72cjogxz 5140 4 not not RB cord-015369-72cjogxz 5140 5 improve improve VB cord-015369-72cjogxz 5140 6 patients patient NNS cord-015369-72cjogxz 5140 7 QOL QOL NNP cord-015369-72cjogxz 5140 8 whereas whereas IN cord-015369-72cjogxz 5140 9 surgery surgery NN cord-015369-72cjogxz 5140 10 significantly significantly RB cord-015369-72cjogxz 5140 11 improved improve VBD cord-015369-72cjogxz 5140 12 the the DT cord-015369-72cjogxz 5140 13 score score NN cord-015369-72cjogxz 5140 14 for for IN cord-015369-72cjogxz 5140 15 bodily bodily JJ cord-015369-72cjogxz 5140 16 pain pain NN cord-015369-72cjogxz 5140 17 . . . cord-015369-72cjogxz 5141 1 After after IN cord-015369-72cjogxz 5141 2 1 1 CD cord-015369-72cjogxz 5141 3 year year NN cord-015369-72cjogxz 5141 4 significantly significantly RB cord-015369-72cjogxz 5141 5 better well JJR cord-015369-72cjogxz 5141 6 scores score NNS cord-015369-72cjogxz 5141 7 for for IN cord-015369-72cjogxz 5141 8 5 5 CD cord-015369-72cjogxz 5141 9 dimensions dimension NNS cord-015369-72cjogxz 5141 10 were be VBD cord-015369-72cjogxz 5141 11 found find VBN cord-015369-72cjogxz 5141 12 in in IN cord-015369-72cjogxz 5141 13 the the DT cord-015369-72cjogxz 5141 14 surgical surgical JJ cord-015369-72cjogxz 5141 15 group group NN cord-015369-72cjogxz 5141 16 . . . cord-015369-72cjogxz 5142 1 For for IN cord-015369-72cjogxz 5142 2 2 2 CD cord-015369-72cjogxz 5142 3 of of IN cord-015369-72cjogxz 5142 4 the the DT cord-015369-72cjogxz 5142 5 3 3 CD cord-015369-72cjogxz 5142 6 chosen choose VBN cord-015369-72cjogxz 5142 7 EFT EFT NNP cord-015369-72cjogxz 5142 8 - - HYPH cord-015369-72cjogxz 5142 9 categories category NNS cord-015369-72cjogxz 5142 10 the the DT cord-015369-72cjogxz 5142 11 surgical surgical JJ cord-015369-72cjogxz 5142 12 group group NN cord-015369-72cjogxz 5142 13 showed show VBD cord-015369-72cjogxz 5142 14 significantly significantly RB cord-015369-72cjogxz 5142 15 worse bad JJR cord-015369-72cjogxz 5142 16 values value NNS cord-015369-72cjogxz 5142 17 . . . cord-015369-72cjogxz 5143 1 When when WRB cord-015369-72cjogxz 5143 2 comparing compare VBG cord-015369-72cjogxz 5143 3 SF SF NNP cord-015369-72cjogxz 5143 4 36 36 CD cord-015369-72cjogxz 5143 5 scores score NNS cord-015369-72cjogxz 5143 6 with with IN cord-015369-72cjogxz 5143 7 data datum NNS cord-015369-72cjogxz 5143 8 obtained obtain VBN cord-015369-72cjogxz 5143 9 by by IN cord-015369-72cjogxz 5143 10 EFT EFT NNP cord-015369-72cjogxz 5143 11 no no DT cord-015369-72cjogxz 5143 12 significant significant JJ cord-015369-72cjogxz 5143 13 differences difference NNS cord-015369-72cjogxz 5143 14 in in IN cord-015369-72cjogxz 5143 15 the the DT cord-015369-72cjogxz 5143 16 QOL QOL NNP cord-015369-72cjogxz 5143 17 between between IN cord-015369-72cjogxz 5143 18 patients patient NNS cord-015369-72cjogxz 5143 19 with with IN cord-015369-72cjogxz 5143 20 normal normal JJ cord-015369-72cjogxz 5143 21 values value NNS cord-015369-72cjogxz 5143 22 and and CC cord-015369-72cjogxz 5143 23 those those DT cord-015369-72cjogxz 5143 24 with with IN cord-015369-72cjogxz 5143 25 abnormal abnormal JJ cord-015369-72cjogxz 5143 26 findings finding NNS cord-015369-72cjogxz 5143 27 were be VBD cord-015369-72cjogxz 5143 28 found find VBN cord-015369-72cjogxz 5143 29 . . . cord-015369-72cjogxz 5144 1 Conclusions conclusion NNS cord-015369-72cjogxz 5144 2 . . . cord-015369-72cjogxz 5145 1 QOL QOL NNP cord-015369-72cjogxz 5145 2 represents represent VBZ cord-015369-72cjogxz 5145 3 a a DT cord-015369-72cjogxz 5145 4 reliable reliable JJ cord-015369-72cjogxz 5145 5 tool tool NN cord-015369-72cjogxz 5145 6 for for IN cord-015369-72cjogxz 5145 7 assessment assessment NN cord-015369-72cjogxz 5145 8 of of IN cord-015369-72cjogxz 5145 9 severity severity NN cord-015369-72cjogxz 5145 10 of of IN cord-015369-72cjogxz 5145 11 disease disease NN cord-015369-72cjogxz 5145 12 and and CC cord-015369-72cjogxz 5145 13 outcome outcome NN cord-015369-72cjogxz 5145 14 following follow VBG cord-015369-72cjogxz 5145 15 therapy therapy NN cord-015369-72cjogxz 5145 16 in in IN cord-015369-72cjogxz 5145 17 persons person NNS cord-015369-72cjogxz 5145 18 with with IN cord-015369-72cjogxz 5145 19 GERD GERD NNP cord-015369-72cjogxz 5145 20 . . . cord-015369-72cjogxz 5146 1 Regarding regard VBG cord-015369-72cjogxz 5146 2 patients patient NNS cord-015369-72cjogxz 5146 3 QOL QOL NNP cord-015369-72cjogxz 5146 4 surgical surgical JJ cord-015369-72cjogxz 5146 5 treatment treatment NN cord-015369-72cjogxz 5146 6 seems seem VBZ cord-015369-72cjogxz 5146 7 superior superior JJ cord-015369-72cjogxz 5146 8 to to IN cord-015369-72cjogxz 5146 9 conservative conservative JJ cord-015369-72cjogxz 5146 10 treatment treatment NN cord-015369-72cjogxz 5146 11 . . . cord-015369-72cjogxz 5147 1 Der Der NNP cord-015369-72cjogxz 5147 2 Hiatus hiatus NN cord-015369-72cjogxz 5148 1 Ösophageuswie Ösophageuswie NNP cord-015369-72cjogxz 5148 2 groß groß NNP cord-015369-72cjogxz 5149 1 ist ist NNP cord-015369-72cjogxz 5150 1 er er UH cord-015369-72cjogxz 5150 2 wirklich wirklich NNP cord-015369-72cjogxz 5150 3 ? ? . cord-015369-72cjogxz 5151 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 5151 2 . . . cord-015369-72cjogxz 5152 1 Es Es NNP cord-015369-72cjogxz 5152 2 wurden wurden VBD cord-015369-72cjogxz 5152 3 24 24 CD cord-015369-72cjogxz 5152 4 Männer Männer NNPS cord-015369-72cjogxz 5152 5 und und IN cord-015369-72cjogxz 5152 6 26 26 CD cord-015369-72cjogxz 5152 7 Frauen Frauen NNP cord-015369-72cjogxz 5152 8 obduziert obduziert RB cord-015369-72cjogxz 5152 9 . . . cord-015369-72cjogxz 5153 1 Mittleres mittlere NNS cord-015369-72cjogxz 5153 2 Alter alter VBP cord-015369-72cjogxz 5153 3 : : : cord-015369-72cjogxz 5153 4 74 74 CD cord-015369-72cjogxz 5153 5 J J NNP cord-015369-72cjogxz 5153 6 ( ( -LRB- cord-015369-72cjogxz 5153 7 range range VBP cord-015369-72cjogxz 5153 8 40 40 CD cord-015369-72cjogxz 5153 9 - - SYM cord-015369-72cjogxz 5153 10 90 90 CD cord-015369-72cjogxz 5153 11 J J NNP cord-015369-72cjogxz 5153 12 ) ) -RRB- cord-015369-72cjogxz 5153 13 . . . cord-015369-72cjogxz 5154 1 Gewicht Gewicht NNP cord-015369-72cjogxz 5154 2 : : : cord-015369-72cjogxz 5154 3 71 71 CD cord-015369-72cjogxz 5154 4 kg kg NNS cord-015369-72cjogxz 5155 1 ( ( -LRB- cord-015369-72cjogxz 5155 2 range range VB cord-015369-72cjogxz 5155 3 40 40 CD cord-015369-72cjogxz 5155 4 - - SYM cord-015369-72cjogxz 5155 5 120 120 CD cord-015369-72cjogxz 5155 6 kg kg NNS cord-015369-72cjogxz 5155 7 ) ) -RRB- cord-015369-72cjogxz 5155 8 , , , cord-015369-72cjogxz 5155 9 Größe Größe NNP cord-015369-72cjogxz 5155 10 1 1 CD cord-015369-72cjogxz 5155 11 , , , cord-015369-72cjogxz 5155 12 68 68 CD cord-015369-72cjogxz 5155 13 m m NN cord-015369-72cjogxz 5155 14 ( ( -LRB- cord-015369-72cjogxz 5155 15 range range NNP cord-015369-72cjogxz 5155 16 1 1 CD cord-015369-72cjogxz 5155 17 , , , cord-015369-72cjogxz 5155 18 83 83 CD cord-015369-72cjogxz 5155 19 m m NNP cord-015369-72cjogxz 5155 20 ) ) -RRB- cord-015369-72cjogxz 5155 21 , , , cord-015369-72cjogxz 5155 22 BMI BMI NNP cord-015369-72cjogxz 5155 23 25 25 CD cord-015369-72cjogxz 5155 24 , , , cord-015369-72cjogxz 5155 25 2 2 CD cord-015369-72cjogxz 5155 26 ( ( -LRB- cord-015369-72cjogxz 5155 27 range range NNP cord-015369-72cjogxz 5155 28 13 13 CD cord-015369-72cjogxz 5155 29 , , , cord-015369-72cjogxz 5155 30 1 1 CD cord-015369-72cjogxz 5155 31 ) ) -RRB- cord-015369-72cjogxz 5155 32 . . . cord-015369-72cjogxz 5156 1 Thoraxumfang Thoraxumfang NNP cord-015369-72cjogxz 5156 2 1 1 CD cord-015369-72cjogxz 5156 3 , , , cord-015369-72cjogxz 5156 4 01 01 CD cord-015369-72cjogxz 5156 5 m m NN cord-015369-72cjogxz 5156 6 ( ( -LRB- cord-015369-72cjogxz 5156 7 range range NNP cord-015369-72cjogxz 5156 8 0 0 CD cord-015369-72cjogxz 5156 9 , , , cord-015369-72cjogxz 5156 10 78 78 CD cord-015369-72cjogxz 5156 11 m m NN cord-015369-72cjogxz 5156 12 ) ) -RRB- cord-015369-72cjogxz 5156 13 . . . cord-015369-72cjogxz 5157 1 Die die VB cord-015369-72cjogxz 5157 2 mittlere mittlere RB cord-015369-72cjogxz 5158 1 HSA HSA NNP cord-015369-72cjogxz 5158 2 betrug betrug NNP cord-015369-72cjogxz 5158 3 5,84 5,84 NNP cord-015369-72cjogxz 5158 4 cm cm NNP cord-015369-72cjogxz 5158 5 2 2 CD cord-015369-72cjogxz 5159 1 ( ( -LRB- cord-015369-72cjogxz 5159 2 range range NNP cord-015369-72cjogxz 5159 3 3,62 3,62 NNP cord-015369-72cjogxz 5159 4 - - HYPH cord-015369-72cjogxz 5159 5 9,56 9,56 CD cord-015369-72cjogxz 5159 6 cm cm NNS cord-015369-72cjogxz 5159 7 2 2 CD cord-015369-72cjogxz 5159 8 ) ) -RRB- cord-015369-72cjogxz 5159 9 . . . cord-015369-72cjogxz 5160 1 Bei Bei NNP cord-015369-72cjogxz 5160 2 allen allen NNP cord-015369-72cjogxz 5160 3 Leichen Leichen NNP cord-015369-72cjogxz 5160 4 war war NN cord-015369-72cjogxz 5160 5 die die VBP cord-015369-72cjogxz 5160 6 Z Z NNP cord-015369-72cjogxz 5160 7 - - HYPH cord-015369-72cjogxz 5160 8 Linie Linie NNP cord-015369-72cjogxz 5160 9 intraabdominal intraabdominal JJ cord-015369-72cjogxz 5160 10 , , , cord-015369-72cjogxz 5160 11 der der NNP cord-015369-72cjogxz 5160 12 Abstand Abstand NNP cord-015369-72cjogxz 5160 13 zum zum NNP cord-015369-72cjogxz 5161 1 HiS his PRP$ cord-015369-72cjogxz 5161 2 Winkel Winkel NNP cord-015369-72cjogxz 5161 3 betrug betrug NNP cord-015369-72cjogxz 5161 4 i -PRON- PRP cord-015369-72cjogxz 5161 5 m be VBP cord-015369-72cjogxz 5161 6 mittel mittel NNP cord-015369-72cjogxz 5161 7 3 3 CD cord-015369-72cjogxz 5161 8 cm cm NNP cord-015369-72cjogxz 5161 9 ( ( -LRB- cord-015369-72cjogxz 5161 10 range range NNP cord-015369-72cjogxz 5161 11 1,2 1,2 CD cord-015369-72cjogxz 5161 12 - - SYM cord-015369-72cjogxz 5161 13 4,8 4,8 CD cord-015369-72cjogxz 5161 14 cm cm NNS cord-015369-72cjogxz 5161 15 ) ) -RRB- cord-015369-72cjogxz 5161 16 . . . cord-015369-72cjogxz 5162 1 Der Der NNP cord-015369-72cjogxz 5162 2 linke linke NN cord-015369-72cjogxz 5162 3 und und XX cord-015369-72cjogxz 5163 1 rechte rechte NNP cord-015369-72cjogxz 5163 2 Zwerchfellschenkel Zwerchfellschenkel NNP cord-015369-72cjogxz 5163 3 war war NN cord-015369-72cjogxz 5163 4 bei bei NNP cord-015369-72cjogxz 5163 5 allen allen NNP cord-015369-72cjogxz 5163 6 exakt exakt NNP cord-015369-72cjogxz 5163 7 gleich gleich NNP cord-015369-72cjogxz 5163 8 lang lang NNP cord-015369-72cjogxz 5163 9 , , , cord-015369-72cjogxz 5164 1 i -PRON- PRP cord-015369-72cjogxz 5164 2 m be VBP cord-015369-72cjogxz 5164 3 Mittel Mittel NNP cord-015369-72cjogxz 5164 4 3,6 3,6 CD cord-015369-72cjogxz 5164 5 cm cm NN cord-015369-72cjogxz 5164 6 ( ( -LRB- cord-015369-72cjogxz 5165 1 range range VBP cord-015369-72cjogxz 5165 2 2,7 2,7 CD cord-015369-72cjogxz 5165 3 - - HYPH cord-015369-72cjogxz 5165 4 4,6 4,6 CD cord-015369-72cjogxz 5165 5 cm cm NNS cord-015369-72cjogxz 5165 6 ) ) -RRB- cord-015369-72cjogxz 5165 7 , , , cord-015369-72cjogxz 5165 8 der der NNP cord-015369-72cjogxz 5165 9 Querdurchmesser Querdurchmesser NNP cord-015369-72cjogxz 5165 10 ( ( -LRB- cord-015369-72cjogxz 5165 11 Segment Segment NNP cord-015369-72cjogxz 5165 12 der der NNP cord-015369-72cjogxz 5165 13 Ö Ö NNP cord-015369-72cjogxz 5165 14 ffnung ffnung NNP cord-015369-72cjogxz 5165 15 ) ) -RRB- cord-015369-72cjogxz 5166 1 i i PRP cord-015369-72cjogxz 5167 1 m m LS cord-015369-72cjogxz 5168 1 Mittel Mittel NNP cord-015369-72cjogxz 5168 2 2,4 2,4 CD cord-015369-72cjogxz 5168 3 cm cm NNP cord-015369-72cjogxz 5169 1 ( ( -LRB- cord-015369-72cjogxz 5169 2 range range NNP cord-015369-72cjogxz 5169 3 1,7 1,7 NNP cord-015369-72cjogxz 5169 4 - - HYPH cord-015369-72cjogxz 5169 5 4,0 4,0 CD cord-015369-72cjogxz 5169 6 cm cm NNP cord-015369-72cjogxz 5169 7 ) ) -RRB- cord-015369-72cjogxz 5169 8 . . . cord-015369-72cjogxz 5170 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 5170 2 . . . cord-015369-72cjogxz 5171 1 Der Der NNP cord-015369-72cjogxz 5171 2 durchschnittliche durchschnittliche NN cord-015369-72cjogxz 5171 3 Hiatusflächeninhalt Hiatusflächeninhalt NNP cord-015369-72cjogxz 5171 4 beträgt beträgt NN cord-015369-72cjogxz 5172 1 5,84 5,84 NNP cord-015369-72cjogxz 5172 2 cm cm NNP cord-015369-72cjogxz 5172 3 2 2 CD cord-015369-72cjogxz 5172 4 . . . cord-015369-72cjogxz 5173 1 Er er UH cord-015369-72cjogxz 5173 2 ist ist NNP cord-015369-72cjogxz 5173 3 direkt direkt NN cord-015369-72cjogxz 5173 4 proportional proportional NN cord-015369-72cjogxz 5173 5 dem dem NNP cord-015369-72cjogxz 5173 6 Thoraxumfang Thoraxumfang NNP cord-015369-72cjogxz 5173 7 und und XX cord-015369-72cjogxz 5174 1 unabhängig unabhängig NNPS cord-015369-72cjogxz 5174 2 von von NNP cord-015369-72cjogxz 5174 3 Größe Größe NNP cord-015369-72cjogxz 5174 4 , , , cord-015369-72cjogxz 5174 5 Gewicht Gewicht NNP cord-015369-72cjogxz 5174 6 , , , cord-015369-72cjogxz 5174 7 BMI BMI NNP cord-015369-72cjogxz 5174 8 und und IN cord-015369-72cjogxz 5174 9 Geschlecht Geschlecht NNP cord-015369-72cjogxz 5174 10 . . . cord-015369-72cjogxz 5175 1 Background background NN cord-015369-72cjogxz 5175 2 . . . cord-015369-72cjogxz 5176 1 In in IN cord-015369-72cjogxz 5176 2 patients patient NNS cord-015369-72cjogxz 5176 3 with with IN cord-015369-72cjogxz 5176 4 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 5176 5 reflux reflux NN cord-015369-72cjogxz 5176 6 disease disease NN cord-015369-72cjogxz 5176 7 ( ( -LRB- cord-015369-72cjogxz 5176 8 GERD GERD NNP cord-015369-72cjogxz 5176 9 ) ) -RRB- cord-015369-72cjogxz 5177 1 esophageal esophageal JJ cord-015369-72cjogxz 5177 2 acid acid NN cord-015369-72cjogxz 5177 3 exposure exposure NN cord-015369-72cjogxz 5177 4 is be VBZ cord-015369-72cjogxz 5177 5 assessed assess VBN cord-015369-72cjogxz 5177 6 with with IN cord-015369-72cjogxz 5177 7 a a DT cord-015369-72cjogxz 5177 8 pH pH NNP cord-015369-72cjogxz 5177 9 probe probe NN cord-015369-72cjogxz 5177 10 placed place VBD cord-015369-72cjogxz 5177 11 5 5 CD cord-015369-72cjogxz 5177 12 cm cm NNS cord-015369-72cjogxz 5177 13 above above IN cord-015369-72cjogxz 5177 14 the the DT cord-015369-72cjogxz 5177 15 manometric manometric JJ cord-015369-72cjogxz 5177 16 lower low JJR cord-015369-72cjogxz 5177 17 esophageal esophageal JJ cord-015369-72cjogxz 5177 18 sphincter sphincter NN cord-015369-72cjogxz 5177 19 ( ( -LRB- cord-015369-72cjogxz 5177 20 LES LES NNP cord-015369-72cjogxz 5177 21 ) ) -RRB- cord-015369-72cjogxz 5177 22 . . . cord-015369-72cjogxz 5178 1 We -PRON- PRP cord-015369-72cjogxz 5178 2 compared compare VBD cord-015369-72cjogxz 5178 3 acid acid JJ cord-015369-72cjogxz 5178 4 exposure exposure NN cord-015369-72cjogxz 5178 5 within within IN cord-015369-72cjogxz 5178 6 and and CC cord-015369-72cjogxz 5178 7 5 5 CD cord-015369-72cjogxz 5178 8 cm cm NNS cord-015369-72cjogxz 5178 9 above above IN cord-015369-72cjogxz 5178 10 the the DT cord-015369-72cjogxz 5178 11 LES LES NNP cord-015369-72cjogxz 5178 12 . . . cord-015369-72cjogxz 5179 1 Methods method NNS cord-015369-72cjogxz 5179 2 . . . cord-015369-72cjogxz 5180 1 Between between IN cord-015369-72cjogxz 5180 2 11/2006 11/2006 CD cord-015369-72cjogxz 5180 3 and and CC cord-015369-72cjogxz 5180 4 12/2008 12/2008 CD cord-015369-72cjogxz 5180 5 , , , cord-015369-72cjogxz 5180 6 178 178 CD cord-015369-72cjogxz 5180 7 patients patient NNS cord-015369-72cjogxz 5180 8 with with IN cord-015369-72cjogxz 5180 9 GERD GERD NNP cord-015369-72cjogxz 5180 10 symptoms symptom NNS cord-015369-72cjogxz 5180 11 ( ( -LRB- cord-015369-72cjogxz 5180 12 45.2 45.2 CD cord-015369-72cjogxz 5180 13 % % NN cord-015369-72cjogxz 5180 14 females female NNS cord-015369-72cjogxz 5180 15 ; ; : cord-015369-72cjogxz 5180 16 age age NN cord-015369-72cjogxz 5180 17 47.4 47.4 CD cord-015369-72cjogxz 5180 18 AE AE NNP cord-015369-72cjogxz 5180 19 15 15 CD cord-015369-72cjogxz 5180 20 years year NNS cord-015369-72cjogxz 5180 21 ) ) -RRB- cord-015369-72cjogxz 5180 22 underwent undergo VBD cord-015369-72cjogxz 5180 23 multilevel multilevel NN cord-015369-72cjogxz 5180 24 pH ph NN cord-015369-72cjogxz 5180 25 monitoring monitoring NN cord-015369-72cjogxz 5180 26 ( ( -LRB- cord-015369-72cjogxz 5180 27 10 10 CD cord-015369-72cjogxz 5180 28 days day NNS cord-015369-72cjogxz 5180 29 off off IN cord-015369-72cjogxz 5180 30 antisecretory antisecretory NNP cord-015369-72cjogxz 5180 31 therapy therapy NN cord-015369-72cjogxz 5180 32 ) ) -RRB- cord-015369-72cjogxz 5180 33 with with IN cord-015369-72cjogxz 5180 34 a a DT cord-015369-72cjogxz 5180 35 catheter catheter NN cord-015369-72cjogxz 5180 36 including include VBG cord-015369-72cjogxz 5180 37 pH pH NNP cord-015369-72cjogxz 5180 38 probes probe NNS cord-015369-72cjogxz 5180 39 5 5 CD cord-015369-72cjogxz 5180 40 cm cm NNS cord-015369-72cjogxz 5180 41 above above IN cord-015369-72cjogxz 5180 42 ( ( -LRB- cord-015369-72cjogxz 5180 43 level level NN cord-015369-72cjogxz 5180 44 þ5 þ5 NNP cord-015369-72cjogxz 5180 45 ) ) -RRB- cord-015369-72cjogxz 5180 46 , , , cord-015369-72cjogxz 5180 47 at at IN cord-015369-72cjogxz 5180 48 ( ( -LRB- cord-015369-72cjogxz 5180 49 level level NN cord-015369-72cjogxz 5180 50 0 0 CD cord-015369-72cjogxz 5180 51 ) ) -RRB- cord-015369-72cjogxz 5180 52 and and CC cord-015369-72cjogxz 5180 53 1.2 1.2 CD cord-015369-72cjogxz 5180 54 cm cm NNS cord-015369-72cjogxz 5180 55 distal distal JJ cord-015369-72cjogxz 5180 56 ( ( -LRB- cord-015369-72cjogxz 5180 57 level level NN cord-015369-72cjogxz 5180 58 À1.2 À1.2 NNP cord-015369-72cjogxz 5180 59 ) ) -RRB- cord-015369-72cjogxz 5180 60 to to IN cord-015369-72cjogxz 5180 61 the the DT cord-015369-72cjogxz 5180 62 proximal proximal JJ cord-015369-72cjogxz 5180 63 LES LES NNP cord-015369-72cjogxz 5180 64 - - HYPH cord-015369-72cjogxz 5180 65 limit limit NN cord-015369-72cjogxz 5180 66 ; ; : cord-015369-72cjogxz 5180 67 % % NN cord-015369-72cjogxz 5180 68 time time NN cord-015369-72cjogxz 5180 69 pH ph NN cord-015369-72cjogxz 5180 70 < < XX cord-015369-72cjogxz 5180 71 4.0 4.0 CD cord-015369-72cjogxz 5180 72 ( ( -LRB- cord-015369-72cjogxz 5180 73 5 5 CD cord-015369-72cjogxz 5180 74 cm cm NNS cord-015369-72cjogxz 5180 75 above above IN cord-015369-72cjogxz 5180 76 LES LES NNP cord-015369-72cjogxz 5180 77 ) ) -RRB- cord-015369-72cjogxz 5181 1 < < XX cord-015369-72cjogxz 5181 2 4.2 4.2 CD cord-015369-72cjogxz 5181 3 % % NN cord-015369-72cjogxz 5181 4 was be VBD cord-015369-72cjogxz 5181 5 considered consider VBN cord-015369-72cjogxz 5181 6 normal normal JJ cord-015369-72cjogxz 5181 7 . . . cord-015369-72cjogxz 5182 1 LES LES NNP cord-015369-72cjogxz 5182 2 length length NN cord-015369-72cjogxz 5182 3 was be VBD cord-015369-72cjogxz 5182 4 > > NFP cord-015369-72cjogxz 5182 5 2 2 CD cord-015369-72cjogxz 5182 6 cm cm NNS cord-015369-72cjogxz 5182 7 in in IN cord-015369-72cjogxz 5182 8 all all DT cord-015369-72cjogxz 5182 9 patients patient NNS cord-015369-72cjogxz 5182 10 . . . cord-015369-72cjogxz 5183 1 Results result NNS cord-015369-72cjogxz 5183 2 . . . cord-015369-72cjogxz 5184 1 5 5 CD cord-015369-72cjogxz 5184 2 cm cm NNS cord-015369-72cjogxz 5184 3 above above IN cord-015369-72cjogxz 5184 4 the the DT cord-015369-72cjogxz 5184 5 LES LES NNP cord-015369-72cjogxz 5184 6 , , , cord-015369-72cjogxz 5184 7 119 119 CD cord-015369-72cjogxz 5184 8 ( ( -LRB- cord-015369-72cjogxz 5184 9 66.9 66.9 CD cord-015369-72cjogxz 5184 10 % % NN cord-015369-72cjogxz 5184 11 ) ) -RRB- cord-015369-72cjogxz 5184 12 and and CC cord-015369-72cjogxz 5184 13 59 59 CD cord-015369-72cjogxz 5184 14 ( ( -LRB- cord-015369-72cjogxz 5184 15 33.1 33.1 CD cord-015369-72cjogxz 5184 16 % % NN cord-015369-72cjogxz 5184 17 ) ) -RRB- cord-015369-72cjogxz 5184 18 patients patient NNS cord-015369-72cjogxz 5184 19 ( ( -LRB- cord-015369-72cjogxz 5184 20 no no DT cord-015369-72cjogxz 5184 21 age age NN cord-015369-72cjogxz 5184 22 difference difference NN cord-015369-72cjogxz 5184 23 , , , cord-015369-72cjogxz 5184 24 p p NN cord-015369-72cjogxz 5184 25 ¼ ¼ CD cord-015369-72cjogxz 5184 26 0.104 0.104 CD cord-015369-72cjogxz 5184 27 ) ) -RRB- cord-015369-72cjogxz 5184 28 had have VBD cord-015369-72cjogxz 5184 29 normal normal JJ cord-015369-72cjogxz 5184 30 and and CC cord-015369-72cjogxz 5184 31 abnormal abnormal JJ cord-015369-72cjogxz 5184 32 acid acid NN cord-015369-72cjogxz 5184 33 exposure exposure NN cord-015369-72cjogxz 5184 34 , , , cord-015369-72cjogxz 5184 35 respectively respectively RB cord-015369-72cjogxz 5184 36 . . . cord-015369-72cjogxz 5185 1 More More JJR cord-015369-72cjogxz 5185 2 women woman NNS cord-015369-72cjogxz 5185 3 had have VBD cord-015369-72cjogxz 5185 4 normal normal JJ cord-015369-72cjogxz 5185 5 acid acid NN cord-015369-72cjogxz 5185 6 exposure exposure NN cord-015369-72cjogxz 5185 7 ( ( -LRB- cord-015369-72cjogxz 5185 8 75 75 CD cord-015369-72cjogxz 5185 9 % % NN cord-015369-72cjogxz 5185 10 vs. vs. IN cord-015369-72cjogxz 5185 11 56.4 56.4 CD cord-015369-72cjogxz 5185 12 % % NN cord-015369-72cjogxz 5185 13 ; ; : cord-015369-72cjogxz 5185 14 p p NN cord-015369-72cjogxz 5185 15 ¼ ¼ CD cord-015369-72cjogxz 5185 16 0.009 0.009 CD cord-015369-72cjogxz 5185 17 ) ) -RRB- cord-015369-72cjogxz 5185 18 . . . cord-015369-72cjogxz 5186 1 In in IN cord-015369-72cjogxz 5186 2 those those DT cord-015369-72cjogxz 5186 3 with with IN cord-015369-72cjogxz 5186 4 normal normal JJ cord-015369-72cjogxz 5186 5 acid acid NN cord-015369-72cjogxz 5186 6 exposure exposure NN cord-015369-72cjogxz 5186 7 , , , cord-015369-72cjogxz 5186 8 time time NN cord-015369-72cjogxz 5186 9 pH pH NNP cord-015369-72cjogxz 5186 10 Conclusions Conclusions NNP cord-015369-72cjogxz 5186 11 . . . cord-015369-72cjogxz 5187 1 Acid acid JJ cord-015369-72cjogxz 5187 2 exposure exposure NN cord-015369-72cjogxz 5187 3 is be VBZ cord-015369-72cjogxz 5187 4 maximal maximal JJ cord-015369-72cjogxz 5187 5 within within IN cord-015369-72cjogxz 5187 6 the the DT cord-015369-72cjogxz 5187 7 LES LES NNP cord-015369-72cjogxz 5187 8 and and CC cord-015369-72cjogxz 5187 9 may may MD cord-015369-72cjogxz 5187 10 explain explain VB cord-015369-72cjogxz 5187 11 why why WRB cord-015369-72cjogxz 5187 12 reflux reflux NN cord-015369-72cjogxz 5187 13 is be VBZ cord-015369-72cjogxz 5187 14 missed miss VBN cord-015369-72cjogxz 5187 15 by by IN cord-015369-72cjogxz 5187 16 probe probe NN cord-015369-72cjogxz 5187 17 placement placement NN cord-015369-72cjogxz 5187 18 5 5 CD cord-015369-72cjogxz 5187 19 cm cm NNS cord-015369-72cjogxz 5187 20 above above IN cord-015369-72cjogxz 5187 21 the the DT cord-015369-72cjogxz 5187 22 LES LES NNP cord-015369-72cjogxz 5187 23 . . . cord-015369-72cjogxz 5188 1 Normative normative JJ cord-015369-72cjogxz 5188 2 values value NNS cord-015369-72cjogxz 5188 3 or or CC cord-015369-72cjogxz 5188 4 Multilevel Multilevel NNP cord-015369-72cjogxz 5188 5 pH ph NN cord-015369-72cjogxz 5188 6 monitoring monitor VBG cord-015369-72cjogxz 5188 7 from from IN cord-015369-72cjogxz 5188 8 asymptomatic asymptomatic JJ cord-015369-72cjogxz 5188 9 persons person NNS cord-015369-72cjogxz 5188 10 are be VBP cord-015369-72cjogxz 5188 11 required require VBN cord-015369-72cjogxz 5188 12 . . . cord-015369-72cjogxz 5189 1 Stellenwert Stellenwert NNP cord-015369-72cjogxz 5189 2 der der NNP cord-015369-72cjogxz 5189 3 ösophagealen ösophagealen NNP cord-015369-72cjogxz 5189 4 kombinierten kombinierten NNP cord-015369-72cjogxz 5190 1 24 24 CD cord-015369-72cjogxz 5190 2 h h NNP cord-015369-72cjogxz 5190 3 - - HYPH cord-015369-72cjogxz 5190 4 Impedanz Impedanz NNP cord-015369-72cjogxz 5190 5 - - HYPH cord-015369-72cjogxz 5190 6 pH pH NNP cord-015369-72cjogxz 5190 7 - - HYPH cord-015369-72cjogxz 5190 8 Metrie Metrie NNP cord-015369-72cjogxz 5190 9 zur zur NNP cord-015369-72cjogxz 5190 10 Refluxdetektion Refluxdetektion NNP cord-015369-72cjogxz 5190 11 bei bei NNP cord-015369-72cjogxz 5190 12 pH pH NNP cord-015369-72cjogxz 5190 13 - - HYPH cord-015369-72cjogxz 5190 14 Metrie Metrie NNP cord-015369-72cjogxz 5190 15 negativen negativen VBD cord-015369-72cjogxz 5190 16 Patienten Patienten NNP cord-015369-72cjogxz 5190 17 Grundlagen Grundlagen NNP cord-015369-72cjogxz 5190 18 . . . cord-015369-72cjogxz 5191 1 Die die VB cord-015369-72cjogxz 5191 2 ösophageale ösophageale JJ cord-015369-72cjogxz 5191 3 24-Stunden 24-stunden CD cord-015369-72cjogxz 5191 4 - - HYPH cord-015369-72cjogxz 5191 5 pH pH NNP cord-015369-72cjogxz 5191 6 - - HYPH cord-015369-72cjogxz 5191 7 Metrie Metrie NNP cord-015369-72cjogxz 5191 8 gilt gilt NN cord-015369-72cjogxz 5191 9 als als NN cord-015369-72cjogxz 5192 1 Gold gold JJ cord-015369-72cjogxz 5192 2 - - HYPH cord-015369-72cjogxz 5192 3 Standard standard NN cord-015369-72cjogxz 5192 4 zur zur NNP cord-015369-72cjogxz 5192 5 Abklärung Abklärung NNP cord-015369-72cjogxz 5193 1 der der NNP cord-015369-72cjogxz 5194 1 Gastro gastro JJ cord-015369-72cjogxz 5194 2 - - HYPH cord-015369-72cjogxz 5194 3 ösophagealen ösophagealen JJ cord-015369-72cjogxz 5194 4 Refluxkrankheit Refluxkrankheit NNP cord-015369-72cjogxz 5194 5 ( ( -LRB- cord-015369-72cjogxz 5194 6 GERD GERD NNP cord-015369-72cjogxz 5194 7 ) ) -RRB- cord-015369-72cjogxz 5194 8 . . . cord-015369-72cjogxz 5195 1 Sie Sie NNP cord-015369-72cjogxz 5195 2 vermag vermag NNP cord-015369-72cjogxz 5195 3 allerdings allerdings NNP cord-015369-72cjogxz 5196 1 nur nur NNP cord-015369-72cjogxz 5196 2 saure saure NNP cord-015369-72cjogxz 5197 1 Refluxe Refluxe NNP cord-015369-72cjogxz 5197 2 zu zu NNP cord-015369-72cjogxz 5197 3 detektieren detektieren NNP cord-015369-72cjogxz 5197 4 ( ( -LRB- cord-015369-72cjogxz 5198 1 pH pH NNP cord-015369-72cjogxz 5198 2 < < XX cord-015369-72cjogxz 5198 3 4 4 CD cord-015369-72cjogxz 5198 4 ) ) -RRB- cord-015369-72cjogxz 5198 5 . . . cord-015369-72cjogxz 5199 1 Neuerdings Neuerdings NNP cord-015369-72cjogxz 5199 2 wird wird NNP cord-015369-72cjogxz 5199 3 die die VBP cord-015369-72cjogxz 5200 1 Diagnostik Diagnostik NNP cord-015369-72cjogxz 5200 2 zunehmend zunehmend NNP cord-015369-72cjogxz 5200 3 um um UH cord-015369-72cjogxz 5200 4 die die VB cord-015369-72cjogxz 5200 5 ösophageale ösophageale NN cord-015369-72cjogxz 5200 6 kombinierte kombinierte NNP cord-015369-72cjogxz 5200 7 24 24 CD cord-015369-72cjogxz 5200 8 h h NNP cord-015369-72cjogxz 5200 9 - - HYPH cord-015369-72cjogxz 5200 10 Impedanz Impedanz NNP cord-015369-72cjogxz 5200 11 - - HYPH cord-015369-72cjogxz 5200 12 pH pH NNP cord-015369-72cjogxz 5200 13 - - HYPH cord-015369-72cjogxz 5200 14 Metrie Metrie NNP cord-015369-72cjogxz 5200 15 erweitert erweitert NN cord-015369-72cjogxz 5200 16 , , , cord-015369-72cjogxz 5200 17 mit mit NNP cord-015369-72cjogxz 5200 18 der der NNP cord-015369-72cjogxz 5200 19 auch auch NNP cord-015369-72cjogxz 5200 20 schwach schwach NNP cord-015369-72cjogxz 5200 21 saure saure NNP cord-015369-72cjogxz 5200 22 oder oder NNP cord-015369-72cjogxz 5200 23 nicht nicht NNP cord-015369-72cjogxz 5200 24 saure saure NNP cord-015369-72cjogxz 5201 1 Refluxe Refluxe NNP cord-015369-72cjogxz 5201 2 registrierbar registrierbar NN cord-015369-72cjogxz 5201 3 sind sind NNP cord-015369-72cjogxz 5201 4 . . . cord-015369-72cjogxz 5202 1 Wieviele Wieviele NNP cord-015369-72cjogxz 5202 2 Refluxpatienten Refluxpatienten NNP cord-015369-72cjogxz 5202 3 bisher bisher NN cord-015369-72cjogxz 5202 4 mit mit NNP cord-015369-72cjogxz 5202 5 der der NNP cord-015369-72cjogxz 5202 6 alleinigen alleinigen NNP cord-015369-72cjogxz 5203 1 24-Stunden 24-stunden CD cord-015369-72cjogxz 5203 2 - - HYPH cord-015369-72cjogxz 5203 3 pH pH NNP cord-015369-72cjogxz 5203 4 - - HYPH cord-015369-72cjogxz 5203 5 Metrie Metrie NNP cord-015369-72cjogxz 5203 6 unentdeckt unentdeckt NNS cord-015369-72cjogxz 5203 7 blieben blieben NNP cord-015369-72cjogxz 5203 8 , , , cord-015369-72cjogxz 5203 9 ist ist NNP cord-015369-72cjogxz 5203 10 unklar unklar NNP cord-015369-72cjogxz 5204 1 und und NNP cord-015369-72cjogxz 5205 1 soll soll NNP cord-015369-72cjogxz 5205 2 durch durch NNP cord-015369-72cjogxz 5205 3 die die VBP cord-015369-72cjogxz 5205 4 vorliegende vorliegende NNP cord-015369-72cjogxz 5205 5 Studie Studie NNP cord-015369-72cjogxz 5205 6 berechnet berechnet NNP cord-015369-72cjogxz 5205 7 werden werden NNP cord-015369-72cjogxz 5205 8 . . . cord-015369-72cjogxz 5206 1 Methodik Methodik NNP cord-015369-72cjogxz 5206 2 . . . cord-015369-72cjogxz 5207 1 Retrospektive Retrospektive NNP cord-015369-72cjogxz 5207 2 Analyse Analyse NNP cord-015369-72cjogxz 5207 3 aller aller FW cord-015369-72cjogxz 5207 4 Patienten Patienten NNP cord-015369-72cjogxz 5207 5 , , , cord-015369-72cjogxz 5207 6 bei bei NNP cord-015369-72cjogxz 5207 7 welchen welchen NNP cord-015369-72cjogxz 5207 8 zur zur NNP cord-015369-72cjogxz 5207 9 GERD GERD NNP cord-015369-72cjogxz 5207 10 - - HYPH cord-015369-72cjogxz 5207 11 Abklärung Abklärung NNP cord-015369-72cjogxz 5207 12 u.a u.a NNP cord-015369-72cjogxz 5207 13 . . NNP cord-015369-72cjogxz 5207 14 eine eine NNP cord-015369-72cjogxz 5207 15 ösophageale ösophageale NNP cord-015369-72cjogxz 5207 16 kombinierte kombinierte NNP cord-015369-72cjogxz 5207 17 24 24 CD cord-015369-72cjogxz 5207 18 Stunden Stunden NNP cord-015369-72cjogxz 5207 19 Impedanz Impedanz NNP cord-015369-72cjogxz 5207 20 - - HYPH cord-015369-72cjogxz 5207 21 pH pH NNP cord-015369-72cjogxz 5207 22 - - HYPH cord-015369-72cjogxz 5207 23 Metrie Metrie NNP cord-015369-72cjogxz 5207 24 durchgeführt durchgeführt NN cord-015369-72cjogxz 5207 25 wurde wurde NNP cord-015369-72cjogxz 5207 26 . . . cord-015369-72cjogxz 5208 1 Verwendet Verwendet NNP cord-015369-72cjogxz 5209 1 wurde wurde NNP cord-015369-72cjogxz 5209 2 ein ein NNP cord-015369-72cjogxz 5209 3 ComforTec ComforTec NNP cord-015369-72cjogxz 5209 4 + + CC cord-015369-72cjogxz 5210 1 MII MII NNP cord-015369-72cjogxz 5210 2 / / SYM cord-015369-72cjogxz 5210 3 pH pH NNP cord-015369-72cjogxz 5210 4 Katheter Katheter NNP cord-015369-72cjogxz 5210 5 ( ( -LRB- cord-015369-72cjogxz 5210 6 Fa Fa NNP cord-015369-72cjogxz 5210 7 . . . cord-015369-72cjogxz 5211 1 Sandhill Sandhill NNP cord-015369-72cjogxz 5211 2 Scientific Scientific NNP cord-015369-72cjogxz 5211 3 , , , cord-015369-72cjogxz 5211 4 Inc Inc NNP cord-015369-72cjogxz 5211 5 ; ; : cord-015369-72cjogxz 5211 6 Nr Nr NNP cord-015369-72cjogxz 5211 7 . . . cord-015369-72cjogxz 5212 1 ZAN ZAN NNP cord-015369-72cjogxz 5212 2 - - HYPH cord-015369-72cjogxz 5212 3 BS-01 BS-01 NNP cord-015369-72cjogxz 5212 4 ) ) -RRB- cord-015369-72cjogxz 5212 5 mit mit NNP cord-015369-72cjogxz 5212 6 einem einem NNP cord-015369-72cjogxz 5212 7 pH pH NNP cord-015369-72cjogxz 5212 8 - - HYPH cord-015369-72cjogxz 5212 9 Sensor Sensor NNP cord-015369-72cjogxz 5212 10 bei bei NNP cord-015369-72cjogxz 5212 11 0 0 CD cord-015369-72cjogxz 5212 12 cm cm NNS cord-015369-72cjogxz 5212 13 , , , cord-015369-72cjogxz 5212 14 sowie sowie NNP cord-015369-72cjogxz 5212 15 5 5 CD cord-015369-72cjogxz 5212 16 Ringelektroden Ringelektroden NNP cord-015369-72cjogxz 5212 17 bei bei NNP cord-015369-72cjogxz 5212 18 drei drei NNP cord-015369-72cjogxz 5212 19 , , , cord-015369-72cjogxz 5212 20 sieben sieben NNP cord-015369-72cjogxz 5212 21 , , , cord-015369-72cjogxz 5212 22 neun neun NNP cord-015369-72cjogxz 5212 23 , , , cord-015369-72cjogxz 5212 24 fünfzehn fünfzehn NNP cord-015369-72cjogxz 5212 25 und und IN cord-015369-72cjogxz 5212 26 siebzehn siebzehn NN cord-015369-72cjogxz 5212 27 Zentimetern Zentimetern NNP cord-015369-72cjogxz 5212 28 von von NNP cord-015369-72cjogxz 5212 29 der der NNP cord-015369-72cjogxz 5212 30 Sondenspitze Sondenspitze NNP cord-015369-72cjogxz 5212 31 . . . cord-015369-72cjogxz 5213 1 Vor Vor NNP cord-015369-72cjogxz 5213 2 Platzierung Platzierung NNP cord-015369-72cjogxz 5213 3 der der NNP cord-015369-72cjogxz 5213 4 Impedanzsonde Impedanzsonde NNP cord-015369-72cjogxz 5213 5 wurde wurde VBD cord-015369-72cjogxz 5213 6 eine eine NNP cord-015369-72cjogxz 5213 7 Ö Ö NNP cord-015369-72cjogxz 5213 8 sophagusmanometrie sophagusmanometrie NN cord-015369-72cjogxz 5213 9 durchgeführt durchgeführt NN cord-015369-72cjogxz 5213 10 , , , cord-015369-72cjogxz 5213 11 u.a u.a NNP cord-015369-72cjogxz 5213 12 . . NNP cord-015369-72cjogxz 5213 13 zur zur NNP cord-015369-72cjogxz 5213 14 Längen Längen NNP cord-015369-72cjogxz 5213 15 - - HYPH cord-015369-72cjogxz 5213 16 und und NNP cord-015369-72cjogxz 5213 17 Lagebestimmeng Lagebestimmeng NNP cord-015369-72cjogxz 5213 18 des des FW cord-015369-72cjogxz 5213 19 LES LES NNP cord-015369-72cjogxz 5213 20 . . . cord-015369-72cjogxz 5214 1 Die Die NNP cord-015369-72cjogxz 5214 2 Platzierung Platzierung NNP cord-015369-72cjogxz 5214 3 des des NNP cord-015369-72cjogxz 5215 1 pH pH NNP cord-015369-72cjogxz 5215 2 - - HYPH cord-015369-72cjogxz 5215 3 Sensors Sensors NNP cord-015369-72cjogxz 5215 4 erfolgte erfolgte NN cord-015369-72cjogxz 5215 5 dann dann NNP cord-015369-72cjogxz 5216 1 5 5 CD cord-015369-72cjogxz 5216 2 cm cm NNS cord-015369-72cjogxz 5216 3 über über NNP cord-015369-72cjogxz 5216 4 dem dem NNP cord-015369-72cjogxz 5216 5 Oberrand Oberrand NNP cord-015369-72cjogxz 5216 6 des des FW cord-015369-72cjogxz 5216 7 LES LES NNP cord-015369-72cjogxz 5216 8 . . . cord-015369-72cjogxz 5217 1 Die die VB cord-015369-72cjogxz 5217 2 Auswertung Auswertung NNP cord-015369-72cjogxz 5217 3 erfolgte erfolgte NN cord-015369-72cjogxz 5217 4 computerunterstützt computerunterstützt VBN cord-015369-72cjogxz 5217 5 ( ( -LRB- cord-015369-72cjogxz 5217 6 , , , cord-015369-72cjogxz 5217 7 , , , cord-015369-72cjogxz 5217 8 BioVIEW bioview VB cord-015369-72cjogxz 5217 9 + + CC cord-015369-72cjogxz 5217 10 '' '' '' cord-015369-72cjogxz 5217 11 , , , cord-015369-72cjogxz 5217 12 Version Version NNP cord-015369-72cjogxz 5217 13 Z00 Z00 NNP cord-015369-72cjogxz 5217 14 - - HYPH cord-015369-72cjogxz 5217 15 0145 0145 CD cord-015369-72cjogxz 5217 16 ; ; . cord-015369-72cjogxz 5218 1 Sandhill Sandhill NNP cord-015369-72cjogxz 5218 2 Scientific Scientific NNP cord-015369-72cjogxz 5218 3 , , , cord-015369-72cjogxz 5218 4 Inc. Inc. NNP cord-015369-72cjogxz 5218 5 ) ) -RRB- cord-015369-72cjogxz 5218 6 Die Die NNP cord-015369-72cjogxz 5218 7 Messdauer Messdauer NNP cord-015369-72cjogxz 5218 8 betrug betrug NNP cord-015369-72cjogxz 5218 9 jeweils jeweils NNP cord-015369-72cjogxz 5218 10 23 23 CD cord-015369-72cjogxz 5218 11 Stunden Stunden NNP cord-015369-72cjogxz 5218 12 . . . cord-015369-72cjogxz 5219 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 5219 2 . . . cord-015369-72cjogxz 5220 1 Es Es NNP cord-015369-72cjogxz 5220 2 wurden wurden VBD cord-015369-72cjogxz 5220 3 159 159 CD cord-015369-72cjogxz 5220 4 kombinierte kombinierte NNS cord-015369-72cjogxz 5220 5 24 24 CD cord-015369-72cjogxz 5220 6 Stunden Stunden NNP cord-015369-72cjogxz 5220 7 Impedanz Impedanz NNP cord-015369-72cjogxz 5220 8 - - HYPH cord-015369-72cjogxz 5220 9 pH pH NNP cord-015369-72cjogxz 5220 10 - - HYPH cord-015369-72cjogxz 5220 11 Metrien Metrien NNP cord-015369-72cjogxz 5220 12 durchgeführt durchgeführt NN cord-015369-72cjogxz 5220 13 . . . cord-015369-72cjogxz 5221 1 Bei Bei NNP cord-015369-72cjogxz 5221 2 107 107 CD cord-015369-72cjogxz 5222 1 Patienten Patienten NNP cord-015369-72cjogxz 5222 2 ( ( -LRB- cord-015369-72cjogxz 5222 3 67,3 67,3 CD cord-015369-72cjogxz 5222 4 % % NN cord-015369-72cjogxz 5222 5 ) ) -RRB- cord-015369-72cjogxz 5222 6 lag lag NN cord-015369-72cjogxz 5222 7 der der NNP cord-015369-72cjogxz 5222 8 DeMeester DeMeester NNP cord-015369-72cjogxz 5222 9 - - HYPH cord-015369-72cjogxz 5222 10 Score Score NNP cord-015369-72cjogxz 5222 11 i -PRON- PRP cord-015369-72cjogxz 5222 12 m be VBP cord-015369-72cjogxz 5222 13 Normbereich Normbereich NNP cord-015369-72cjogxz 5222 14 ( ( -LRB- cord-015369-72cjogxz 5222 15 < < XX cord-015369-72cjogxz 5222 16 14,7 14,7 CD cord-015369-72cjogxz 5222 17 ) ) -RRB- cord-015369-72cjogxz 5222 18 . . . cord-015369-72cjogxz 5223 1 Dreizehn Dreizehn NNP cord-015369-72cjogxz 5223 2 dieser dieser NNP cord-015369-72cjogxz 5224 1 Patienten Patienten NNP cord-015369-72cjogxz 5224 2 mit mit VBP cord-015369-72cjogxz 5224 3 physiologischem physiologischem NNP cord-015369-72cjogxz 5224 4 DeMeester DeMeester NNP cord-015369-72cjogxz 5224 5 - - HYPH cord-015369-72cjogxz 5224 6 Score score NN cord-015369-72cjogxz 5224 7 zeigten zeigten XX cord-015369-72cjogxz 5224 8 eine eine NNP cord-015369-72cjogxz 5224 9 pathologische pathologische NN cord-015369-72cjogxz 5224 10 Anzahl Anzahl NNP cord-015369-72cjogxz 5225 1 von von NNP cord-015369-72cjogxz 5226 1 > > XX cord-015369-72cjogxz 5227 1 73 73 CD cord-015369-72cjogxz 5227 2 Refluxen Refluxen NNP cord-015369-72cjogxz 5227 3 in in IN cord-015369-72cjogxz 5227 4 24 24 CD cord-015369-72cjogxz 5227 5 Stunden Stunden NNP cord-015369-72cjogxz 5227 6 ( ( -LRB- cord-015369-72cjogxz 5227 7 12,1 12,1 CD cord-015369-72cjogxz 5227 8 % % NN cord-015369-72cjogxz 5227 9 ; ; : cord-015369-72cjogxz 5227 10 das das NNP cord-015369-72cjogxz 5227 11 entspricht entspricht NNP cord-015369-72cjogxz 5227 12 8,2 8,2 CD cord-015369-72cjogxz 5227 13 % % NN cord-015369-72cjogxz 5227 14 der der NNP cord-015369-72cjogxz 5227 15 gesamten gesamten NNP cord-015369-72cjogxz 5227 16 Patientenpopulation Patientenpopulation NNP cord-015369-72cjogxz 5227 17 ) ) -RRB- cord-015369-72cjogxz 5227 18 . . . cord-015369-72cjogxz 5228 1 D.h D.h NNP cord-015369-72cjogxz 5228 2 . . NNP cord-015369-72cjogxz 5228 3 , , , cord-015369-72cjogxz 5228 4 bei bei NNP cord-015369-72cjogxz 5228 5 8,2 8,2 CD cord-015369-72cjogxz 5228 6 % % NN cord-015369-72cjogxz 5228 7 der der NNP cord-015369-72cjogxz 5228 8 Patienten Patienten NNP cord-015369-72cjogxz 5228 9 wurde wurde VBD cord-015369-72cjogxz 5228 10 eine eine NNP cord-015369-72cjogxz 5229 1 pathologische pathologische NNP cord-015369-72cjogxz 5229 2 Refluxaktivität Refluxaktivität NNP cord-015369-72cjogxz 5229 3 durch durch NNP cord-015369-72cjogxz 5230 1 eine eine NNP cord-015369-72cjogxz 5230 2 alleinige alleinige NNP cord-015369-72cjogxz 5230 3 24 24 CD cord-015369-72cjogxz 5230 4 h h NNP cord-015369-72cjogxz 5230 5 - - HYPH cord-015369-72cjogxz 5230 6 pH pH NNP cord-015369-72cjogxz 5230 7 - - HYPH cord-015369-72cjogxz 5230 8 Metrie Metrie NNP cord-015369-72cjogxz 5230 9 nicht nicht NNP cord-015369-72cjogxz 5230 10 erfasst erfasst NNP cord-015369-72cjogxz 5230 11 . . . cord-015369-72cjogxz 5231 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 5231 2 . . . cord-015369-72cjogxz 5232 1 Bei Bei NNP cord-015369-72cjogxz 5232 2 Vorliegen Vorliegen NNP cord-015369-72cjogxz 5232 3 einer einer NNP cord-015369-72cjogxz 5232 4 unauffälligen unauffälligen NNP cord-015369-72cjogxz 5232 5 ösophagealen ösophagealen NNP cord-015369-72cjogxz 5233 1 24 24 CD cord-015369-72cjogxz 5233 2 h h NN cord-015369-72cjogxz 5233 3 - - HYPH cord-015369-72cjogxz 5233 4 pH pH NNP cord-015369-72cjogxz 5233 5 Metrie Metrie NNP cord-015369-72cjogxz 5233 6 sollte sollte NNP cord-015369-72cjogxz 5233 7 , , , cord-015369-72cjogxz 5233 8 wenn wenn NNP cord-015369-72cjogxz 5233 9 verfü verfü NNP cord-015369-72cjogxz 5233 10 gbar gbar NNP cord-015369-72cjogxz 5233 11 , , , cord-015369-72cjogxz 5233 12 noch noch NNP cord-015369-72cjogxz 5233 13 eine eine NNP cord-015369-72cjogxz 5233 14 ösophageale ösophageale NNP cord-015369-72cjogxz 5234 1 24 24 CD cord-015369-72cjogxz 5234 2 h h NNP cord-015369-72cjogxz 5234 3 - - HYPH cord-015369-72cjogxz 5234 4 Impedanzmessung Impedanzmessung NNP cord-015369-72cjogxz 5234 5 angeschlossen angeschlossen NNP cord-015369-72cjogxz 5234 6 werden werden NNP cord-015369-72cjogxz 5234 7 , , , cord-015369-72cjogxz 5235 1 um um UH cord-015369-72cjogxz 5235 2 weitere weitere NNP cord-015369-72cjogxz 5235 3 8,2 8,2 CD cord-015369-72cjogxz 5235 4 % % NN cord-015369-72cjogxz 5235 5 der der NNP cord-015369-72cjogxz 5235 6 Patienten Patienten NNP cord-015369-72cjogxz 5236 1 vor vor NNP cord-015369-72cjogxz 5236 2 einer einer NNP cord-015369-72cjogxz 5236 3 möglichen möglichen NNP cord-015369-72cjogxz 5236 4 Fehldiagnose Fehldiagnose NNP cord-015369-72cjogxz 5236 5 zu zu NNP cord-015369-72cjogxz 5236 6 bewahren bewahren NN cord-015369-72cjogxz 5236 7 . . . cord-015369-72cjogxz 5237 1 Reflux reflux NN cord-015369-72cjogxz 5237 2 characteristics characteristic NNS cord-015369-72cjogxz 5237 3 and and CC cord-015369-72cjogxz 5237 4 symptoms symptom NNS cord-015369-72cjogxz 5237 5 off off RB cord-015369-72cjogxz 5237 6 and and CC cord-015369-72cjogxz 5237 7 on on IN cord-015369-72cjogxz 5237 8 proton proton NN cord-015369-72cjogxz 5237 9 pump pump NN cord-015369-72cjogxz 5237 10 inhibitor inhibitor NN cord-015369-72cjogxz 5237 11 medication medication NN cord-015369-72cjogxz 5237 12 : : : cord-015369-72cjogxz 5237 13 An an DT cord-015369-72cjogxz 5237 14 impedance impedance NN cord-015369-72cjogxz 5237 15 - - HYPH cord-015369-72cjogxz 5237 16 pH ph NN cord-015369-72cjogxz 5237 17 - - HYPH cord-015369-72cjogxz 5237 18 study study NN cord-015369-72cjogxz 5237 19 in in IN cord-015369-72cjogxz 5237 20 50 50 CD cord-015369-72cjogxz 5237 21 patients patient NNS cord-015369-72cjogxz 5237 22 with with IN cord-015369-72cjogxz 5237 23 gastroesopheal gastroesopheal NN cord-015369-72cjogxz 5237 24 reflux reflux NN cord-015369-72cjogxz 5237 25 disease disease NN cord-015369-72cjogxz 5237 26 Background Background NNP cord-015369-72cjogxz 5237 27 . . . cord-015369-72cjogxz 5238 1 The the DT cord-015369-72cjogxz 5238 2 influence influence NN cord-015369-72cjogxz 5238 3 of of IN cord-015369-72cjogxz 5238 4 proton proton NN cord-015369-72cjogxz 5238 5 pump pump NN cord-015369-72cjogxz 5238 6 inhibitor inhibitor NN cord-015369-72cjogxz 5238 7 ( ( -LRB- cord-015369-72cjogxz 5238 8 PPI PPI NNP cord-015369-72cjogxz 5238 9 ) ) -RRB- cord-015369-72cjogxz 5238 10 medication medication NN cord-015369-72cjogxz 5238 11 on on IN cord-015369-72cjogxz 5238 12 results result NNS cord-015369-72cjogxz 5238 13 of of IN cord-015369-72cjogxz 5238 14 multichannel multichannel JJ cord-015369-72cjogxz 5238 15 intraluminal intraluminal JJ cord-015369-72cjogxz 5238 16 impedance impedance NN cord-015369-72cjogxz 5238 17 and and CC cord-015369-72cjogxz 5238 18 pH ph NN cord-015369-72cjogxz 5238 19 monitoring monitoring NN cord-015369-72cjogxz 5238 20 ( ( -LRB- cord-015369-72cjogxz 5238 21 MII MII NNP cord-015369-72cjogxz 5238 22 - - HYPH cord-015369-72cjogxz 5238 23 pH pH NNP cord-015369-72cjogxz 5238 24 ) ) -RRB- cord-015369-72cjogxz 5238 25 is be VBZ cord-015369-72cjogxz 5238 26 controversial controversial JJ cord-015369-72cjogxz 5238 27 . . . cord-015369-72cjogxz 5239 1 Aim aim VB cord-015369-72cjogxz 5239 2 of of IN cord-015369-72cjogxz 5239 3 this this DT cord-015369-72cjogxz 5239 4 study study NN cord-015369-72cjogxz 5239 5 was be VBD cord-015369-72cjogxz 5239 6 to to TO cord-015369-72cjogxz 5239 7 investigate investigate VB cord-015369-72cjogxz 5239 8 the the DT cord-015369-72cjogxz 5239 9 effect effect NN cord-015369-72cjogxz 5239 10 of of IN cord-015369-72cjogxz 5239 11 esomeprazole esomeprazole NN cord-015369-72cjogxz 5239 12 40 40 CD cord-015369-72cjogxz 5239 13 mg mg NN cord-015369-72cjogxz 5239 14 bid bid NN cord-015369-72cjogxz 5239 15 on on IN cord-015369-72cjogxz 5239 16 MII MII NNP cord-015369-72cjogxz 5239 17 - - HYPH cord-015369-72cjogxz 5239 18 pH pH NNP cord-015369-72cjogxz 5239 19 results result NNS cord-015369-72cjogxz 5239 20 . . . cord-015369-72cjogxz 5240 1 Methods method NNS cord-015369-72cjogxz 5240 2 . . . cord-015369-72cjogxz 5241 1 Fifty fifty CD cord-015369-72cjogxz 5241 2 patients patient NNS cord-015369-72cjogxz 5241 3 ( ( -LRB- cord-015369-72cjogxz 5241 4 24 24 CD cord-015369-72cjogxz 5241 5 f f NNP cord-015369-72cjogxz 5241 6 , , , cord-015369-72cjogxz 5241 7 46.7a 46.7a CD cord-015369-72cjogxz 5241 8 , , , cord-015369-72cjogxz 5241 9 range range VBP cord-015369-72cjogxz 5241 10 20 20 CD cord-015369-72cjogxz 5241 11 - - HYPH cord-015369-72cjogxz 5241 12 66a 66a NN cord-015369-72cjogxz 5241 13 ) ) -RRB- cord-015369-72cjogxz 5241 14 with with IN cord-015369-72cjogxz 5241 15 heartburn heartburn NN cord-015369-72cjogxz 5241 16 or or CC cord-015369-72cjogxz 5241 17 regurgitation regurgitation NN cord-015369-72cjogxz 5241 18 underwent undergo VBD cord-015369-72cjogxz 5241 19 24 24 CD cord-015369-72cjogxz 5241 20 h h NN cord-015369-72cjogxz 5241 21 MII MII NNP cord-015369-72cjogxz 5241 22 - - HYPH cord-015369-72cjogxz 5241 23 pH pH NNP cord-015369-72cjogxz 5241 24 off off RP cord-015369-72cjogxz 5242 1 ( ( -LRB- cord-015369-72cjogxz 5242 2 PPI PPI NNP cord-015369-72cjogxz 5242 3 paused pause VBD cord-015369-72cjogxz 5242 4 for for IN cord-015369-72cjogxz 5242 5 10 10 CD cord-015369-72cjogxz 5242 6 days day NNS cord-015369-72cjogxz 5242 7 ) ) -RRB- cord-015369-72cjogxz 5242 8 and and CC cord-015369-72cjogxz 5242 9 on on IN cord-015369-72cjogxz 5242 10 PPI PPI NNP cord-015369-72cjogxz 5242 11 ( ( -LRB- cord-015369-72cjogxz 5242 12 Esomeprazole Esomeprazole NNP cord-015369-72cjogxz 5242 13 40 40 CD cord-015369-72cjogxz 5242 14 mg mg NNP cord-015369-72cjogxz 5242 15 bid bid NN cord-015369-72cjogxz 5242 16 for for IN cord-015369-72cjogxz 5242 17 14 14 CD cord-015369-72cjogxz 5242 18 days day NNS cord-015369-72cjogxz 5242 19 ) ) -RRB- cord-015369-72cjogxz 5242 20 . . . cord-015369-72cjogxz 5243 1 Patients patient NNS cord-015369-72cjogxz 5243 2 recorded record VBD cord-015369-72cjogxz 5243 3 symptoms symptom NNS cord-015369-72cjogxz 5243 4 , , , cord-015369-72cjogxz 5243 5 meals meal NNS cord-015369-72cjogxz 5243 6 and and CC cord-015369-72cjogxz 5243 7 recumbent recumbent JJ cord-015369-72cjogxz 5243 8 periods period NNS cord-015369-72cjogxz 5243 9 . . . cord-015369-72cjogxz 5244 1 Tracings tracing NNS cord-015369-72cjogxz 5244 2 were be VBD cord-015369-72cjogxz 5244 3 automatically automatically RB cord-015369-72cjogxz 5244 4 analyzed analyze VBN cord-015369-72cjogxz 5244 5 and and CC cord-015369-72cjogxz 5244 6 manually manually RB cord-015369-72cjogxz 5244 7 reviewed review VBN cord-015369-72cjogxz 5244 8 . . . cord-015369-72cjogxz 5245 1 Variables variable NNS cord-015369-72cjogxz 5245 2 for for IN cord-015369-72cjogxz 5245 3 comparison comparison NN cord-015369-72cjogxz 5245 4 were be VBD cord-015369-72cjogxz 5245 5 number number NN cord-015369-72cjogxz 5245 6 of of IN cord-015369-72cjogxz 5245 7 acid acid NN cord-015369-72cjogxz 5245 8 and and CC cord-015369-72cjogxz 5245 9 nonacid nonacid JJ cord-015369-72cjogxz 5245 10 refluxes refluxes NNP cord-015369-72cjogxz 5245 11 , , , cord-015369-72cjogxz 5245 12 heartburn heartburn NN cord-015369-72cjogxz 5245 13 and and CC cord-015369-72cjogxz 5245 14 regurgitation regurgitation NN cord-015369-72cjogxz 5245 15 episodes episode NNS cord-015369-72cjogxz 5245 16 and and CC cord-015369-72cjogxz 5245 17 symptom symptom NN cord-015369-72cjogxz 5245 18 to to IN cord-015369-72cjogxz 5245 19 reflux reflux NN cord-015369-72cjogxz 5245 20 correlation correlation NN cord-015369-72cjogxz 5245 21 by by IN cord-015369-72cjogxz 5245 22 symptom symptom NN cord-015369-72cjogxz 5245 23 index index NN cord-015369-72cjogxz 5245 24 ( ( -LRB- cord-015369-72cjogxz 5245 25 SI SI NNP cord-015369-72cjogxz 5245 26 ) ) -RRB- cord-015369-72cjogxz 5245 27 . . . cord-015369-72cjogxz 5246 1 Results result NNS cord-015369-72cjogxz 5246 2 . . . cord-015369-72cjogxz 5247 1 See see VB cord-015369-72cjogxz 5247 2 Tables table NNS cord-015369-72cjogxz 5247 3 1 1 CD cord-015369-72cjogxz 5247 4 and and CC cord-015369-72cjogxz 5247 5 2 2 CD cord-015369-72cjogxz 5247 6 . . . cord-015369-72cjogxz 5248 1 Conclusions conclusion NNS cord-015369-72cjogxz 5248 2 . . . cord-015369-72cjogxz 5249 1 Esomeprazole Esomeprazole NNP cord-015369-72cjogxz 5249 2 40 40 CD cord-015369-72cjogxz 5249 3 mg mg NN cord-015369-72cjogxz 5249 4 bid bid NN cord-015369-72cjogxz 5249 5 resulted result VBD cord-015369-72cjogxz 5249 6 in in IN cord-015369-72cjogxz 5249 7 significantly significantly RB cord-015369-72cjogxz 5249 8 lower low JJR cord-015369-72cjogxz 5249 9 numbers number NNS cord-015369-72cjogxz 5249 10 of of IN cord-015369-72cjogxz 5249 11 acid acid NN cord-015369-72cjogxz 5249 12 but but CC cord-015369-72cjogxz 5249 13 not not RB cord-015369-72cjogxz 5249 14 total total JJ cord-015369-72cjogxz 5249 15 number number NN cord-015369-72cjogxz 5249 16 of of IN cord-015369-72cjogxz 5249 17 refluxes refluxes NNP cord-015369-72cjogxz 5249 18 . . . cord-015369-72cjogxz 5250 1 Peristant peristant JJ cord-015369-72cjogxz 5250 2 regurgitation regurgitation NN cord-015369-72cjogxz 5250 3 on on IN cord-015369-72cjogxz 5250 4 medication medication NN cord-015369-72cjogxz 5250 5 was be VBD cord-015369-72cjogxz 5250 6 more more RBR cord-015369-72cjogxz 5250 7 frequent frequent JJ cord-015369-72cjogxz 5250 8 than than IN cord-015369-72cjogxz 5250 9 persistant persistant JJ cord-015369-72cjogxz 5250 10 heartburn heartburn NN cord-015369-72cjogxz 5250 11 . . . cord-015369-72cjogxz 5251 1 On on IN cord-015369-72cjogxz 5251 2 PPI PPI NNP cord-015369-72cjogxz 5251 3 reflux reflux NN cord-015369-72cjogxz 5251 4 monitoring monitoring NN cord-015369-72cjogxz 5251 5 has have VBZ cord-015369-72cjogxz 5251 6 a a DT cord-015369-72cjogxz 5251 7 lower low JJR cord-015369-72cjogxz 5251 8 diag diag NN cord-015369-72cjogxz 5251 9 - - HYPH cord-015369-72cjogxz 5251 10 nostic nostic JJ cord-015369-72cjogxz 5251 11 yield yield NN cord-015369-72cjogxz 5251 12 , , , cord-015369-72cjogxz 5251 13 but but CC cord-015369-72cjogxz 5251 14 contains contain VBZ cord-015369-72cjogxz 5251 15 more more RBR cord-015369-72cjogxz 5251 16 clinically clinically RB cord-015369-72cjogxz 5251 17 useful useful JJ cord-015369-72cjogxz 5251 18 information information NN cord-015369-72cjogxz 5251 19 in in IN cord-015369-72cjogxz 5251 20 patients patient NNS cord-015369-72cjogxz 5251 21 with with IN cord-015369-72cjogxz 5251 22 symptoms symptom NNS cord-015369-72cjogxz 5251 23 persisting persist VBG cord-015369-72cjogxz 5251 24 on on IN cord-015369-72cjogxz 5251 25 PPI PPI NNP cord-015369-72cjogxz 5251 26 medication medication NN cord-015369-72cjogxz 5251 27 . . . cord-015369-72cjogxz 5252 1 The the DT cord-015369-72cjogxz 5252 2 incidence incidence NN cord-015369-72cjogxz 5252 3 of of IN cord-015369-72cjogxz 5252 4 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 5252 5 reflux reflux NN cord-015369-72cjogxz 5252 6 after after IN cord-015369-72cjogxz 5252 7 transthoracic transthoracic NNP cord-015369-72cjogxz 5252 8 esophagocardiomyotomy esophagocardiomyotomy NNP cord-015369-72cjogxz 5252 9 without without IN cord-015369-72cjogxz 5252 10 fundoplication fundoplication NN cord-015369-72cjogxz 5252 11 : : : cord-015369-72cjogxz 5252 12 a a DT cord-015369-72cjogxz 5252 13 long long JJ cord-015369-72cjogxz 5252 14 term term NN cord-015369-72cjogxz 5252 15 follow follow NN cord-015369-72cjogxz 5252 16 - - HYPH cord-015369-72cjogxz 5252 17 up up NN cord-015369-72cjogxz 5252 18 Background Background NNP cord-015369-72cjogxz 5252 19 . . . cord-015369-72cjogxz 5253 1 Evaluation evaluation NN cord-015369-72cjogxz 5253 2 of of IN cord-015369-72cjogxz 5253 3 the the DT cord-015369-72cjogxz 5253 4 long long JJ cord-015369-72cjogxz 5253 5 term term NN cord-015369-72cjogxz 5253 6 results result NNS cord-015369-72cjogxz 5253 7 of of IN cord-015369-72cjogxz 5253 8 Heller Heller NNP cord-015369-72cjogxz 5253 9 's 's POS cord-015369-72cjogxz 5253 10 myotomy myotomy NN cord-015369-72cjogxz 5253 11 performed perform VBD cord-015369-72cjogxz 5253 12 over over IN cord-015369-72cjogxz 5253 13 a a DT cord-015369-72cjogxz 5253 14 lateral lateral JJ cord-015369-72cjogxz 5253 15 thoracotomy thoracotomy NN cord-015369-72cjogxz 5253 16 without without IN cord-015369-72cjogxz 5253 17 additional additional JJ cord-015369-72cjogxz 5253 18 fundoplication fundoplication NN cord-015369-72cjogxz 5253 19 . . . cord-015369-72cjogxz 5254 1 Methods method NNS cord-015369-72cjogxz 5254 2 . . . cord-015369-72cjogxz 5255 1 Fourty fourty CD cord-015369-72cjogxz 5255 2 patients patient NNS cord-015369-72cjogxz 5255 3 ( ( -LRB- cord-015369-72cjogxz 5255 4 17 17 CD cord-015369-72cjogxz 5255 5 males male NNS cord-015369-72cjogxz 5255 6 , , , cord-015369-72cjogxz 5255 7 23 23 CD cord-015369-72cjogxz 5255 8 females female NNS cord-015369-72cjogxz 5255 9 ; ; : cord-015369-72cjogxz 5255 10 mean mean VB cord-015369-72cjogxz 5255 11 age age NN cord-015369-72cjogxz 5255 12 43.2 43.2 CD cord-015369-72cjogxz 5255 13 years year NNS cord-015369-72cjogxz 5255 14 ; ; : cord-015369-72cjogxz 5255 15 range range NN cord-015369-72cjogxz 5255 16 : : : cord-015369-72cjogxz 5255 17 14 14 CD cord-015369-72cjogxz 5255 18 - - SYM cord-015369-72cjogxz 5255 19 63 63 CD cord-015369-72cjogxz 5255 20 years year NNS cord-015369-72cjogxz 5255 21 ) ) -RRB- cord-015369-72cjogxz 5255 22 were be VBD cord-015369-72cjogxz 5255 23 operated operate VBN cord-015369-72cjogxz 5255 24 between between IN cord-015369-72cjogxz 5255 25 1985 1985 CD cord-015369-72cjogxz 5255 26 and and CC cord-015369-72cjogxz 5255 27 2000 2000 CD cord-015369-72cjogxz 5255 28 . . . cord-015369-72cjogxz 5256 1 Preoperative preoperative JJ cord-015369-72cjogxz 5256 2 evaluation evaluation NN cord-015369-72cjogxz 5256 3 included include VBD cord-015369-72cjogxz 5256 4 clinical clinical JJ cord-015369-72cjogxz 5256 5 scoring scoring NN cord-015369-72cjogxz 5256 6 of of IN cord-015369-72cjogxz 5256 7 symptoms symptom NNS cord-015369-72cjogxz 5256 8 , , , cord-015369-72cjogxz 5256 9 esophagogram esophagogram NNP cord-015369-72cjogxz 5256 10 , , , cord-015369-72cjogxz 5256 11 endoscopy endoscopy NNP cord-015369-72cjogxz 5256 12 , , , cord-015369-72cjogxz 5256 13 manometry manometry NN cord-015369-72cjogxz 5256 14 and and CC cord-015369-72cjogxz 5256 15 24-hours 24-hours CD cord-015369-72cjogxz 5256 16 ph ph NNP cord-015369-72cjogxz 5256 17 - - HYPH cord-015369-72cjogxz 5256 18 metry metry NNP cord-015369-72cjogxz 5256 19 . . . cord-015369-72cjogxz 5257 1 At at IN cord-015369-72cjogxz 5257 2 the the DT cord-015369-72cjogxz 5257 3 follow follow NN cord-015369-72cjogxz 5257 4 - - HYPH cord-015369-72cjogxz 5257 5 up up NN cord-015369-72cjogxz 5257 6 investigation investigation NN cord-015369-72cjogxz 5257 7 , , , cord-015369-72cjogxz 5257 8 the the DT cord-015369-72cjogxz 5257 9 preoperative preoperative JJ cord-015369-72cjogxz 5257 10 evaluation evaluation NN cord-015369-72cjogxz 5257 11 was be VBD cord-015369-72cjogxz 5257 12 repeated repeat VBN cord-015369-72cjogxz 5257 13 in in IN cord-015369-72cjogxz 5257 14 all all DT cord-015369-72cjogxz 5257 15 patients patient NNS cord-015369-72cjogxz 5257 16 , , , cord-015369-72cjogxz 5257 17 adding add VBG cord-015369-72cjogxz 5257 18 a a DT cord-015369-72cjogxz 5257 19 histological histological JJ cord-015369-72cjogxz 5257 20 workup workup NN cord-015369-72cjogxz 5257 21 of of IN cord-015369-72cjogxz 5257 22 the the DT cord-015369-72cjogxz 5257 23 distal distal JJ cord-015369-72cjogxz 5257 24 esophageal esophageal JJ cord-015369-72cjogxz 5257 25 mucosa mucosa NN cord-015369-72cjogxz 5257 26 . . . cord-015369-72cjogxz 5258 1 The the DT cord-015369-72cjogxz 5258 2 mean mean JJ cord-015369-72cjogxz 5258 3 duration duration NN cord-015369-72cjogxz 5258 4 of of IN cord-015369-72cjogxz 5258 5 follow follow NN cord-015369-72cjogxz 5258 6 - - HYPH cord-015369-72cjogxz 5258 7 up up NN cord-015369-72cjogxz 5258 8 after after IN cord-015369-72cjogxz 5258 9 surgery surgery NN cord-015369-72cjogxz 5258 10 was be VBD cord-015369-72cjogxz 5258 11 10.3 10.3 CD cord-015369-72cjogxz 5258 12 years year NNS cord-015369-72cjogxz 5258 13 , , , cord-015369-72cjogxz 5258 14 ranging range VBG cord-015369-72cjogxz 5258 15 from from IN cord-015369-72cjogxz 5258 16 3 3 CD cord-015369-72cjogxz 5258 17 to to TO cord-015369-72cjogxz 5258 18 16 16 CD cord-015369-72cjogxz 5258 19 years year NNS cord-015369-72cjogxz 5258 20 . . . cord-015369-72cjogxz 5259 1 Results result NNS cord-015369-72cjogxz 5259 2 . . . cord-015369-72cjogxz 5260 1 The the DT cord-015369-72cjogxz 5260 2 clinical clinical JJ cord-015369-72cjogxz 5260 3 scores score NNS cord-015369-72cjogxz 5260 4 improved improve VBD cord-015369-72cjogxz 5260 5 significantly significantly RB cord-015369-72cjogxz 5260 6 : : : cord-015369-72cjogxz 5260 7 Excellent excellent JJ cord-015369-72cjogxz 5260 8 relief relief NN cord-015369-72cjogxz 5260 9 from from IN cord-015369-72cjogxz 5260 10 dysphagia dysphagia NN cord-015369-72cjogxz 5260 11 was be VBD cord-015369-72cjogxz 5260 12 present present JJ cord-015369-72cjogxz 5260 13 in in IN cord-015369-72cjogxz 5260 14 86 86 CD cord-015369-72cjogxz 5260 15 % % NN cord-015369-72cjogxz 5260 16 , , , cord-015369-72cjogxz 5260 17 little little JJ cord-015369-72cjogxz 5260 18 or or CC cord-015369-72cjogxz 5260 19 no no DT cord-015369-72cjogxz 5260 20 regurgitation regurgitation NN cord-015369-72cjogxz 5260 21 was be VBD cord-015369-72cjogxz 5260 22 found find VBN cord-015369-72cjogxz 5260 23 in in IN cord-015369-72cjogxz 5260 24 79 79 CD cord-015369-72cjogxz 5260 25 % % NN cord-015369-72cjogxz 5260 26 , , , cord-015369-72cjogxz 5260 27 little little JJ cord-015369-72cjogxz 5260 28 or or CC cord-015369-72cjogxz 5260 29 no no DT cord-015369-72cjogxz 5260 30 retrosternal retrosternal JJ cord-015369-72cjogxz 5260 31 spasms spasm NNS cord-015369-72cjogxz 5260 32 were be VBD cord-015369-72cjogxz 5260 33 reported report VBN cord-015369-72cjogxz 5260 34 by by IN cord-015369-72cjogxz 5260 35 72 72 CD cord-015369-72cjogxz 5260 36 % % NN cord-015369-72cjogxz 5260 37 of of IN cord-015369-72cjogxz 5260 38 the the DT cord-015369-72cjogxz 5260 39 patients patient NNS cord-015369-72cjogxz 5260 40 . . . cord-015369-72cjogxz 5261 1 Esophagogram Esophagogram NNP cord-015369-72cjogxz 5261 2 showed show VBD cord-015369-72cjogxz 5261 3 an an DT cord-015369-72cjogxz 5261 4 overall overall JJ cord-015369-72cjogxz 5261 5 esophageal esophageal JJ cord-015369-72cjogxz 5261 6 dilatation dilatation NN cord-015369-72cjogxz 5261 7 in in IN cord-015369-72cjogxz 5261 8 all all DT cord-015369-72cjogxz 5261 9 patients patient NNS cord-015369-72cjogxz 5261 10 but but CC cord-015369-72cjogxz 5261 11 no no DT cord-015369-72cjogxz 5261 12 significant significant JJ cord-015369-72cjogxz 5261 13 obstruction obstruction NN cord-015369-72cjogxz 5261 14 at at IN cord-015369-72cjogxz 5261 15 the the DT cord-015369-72cjogxz 5261 16 esophagogastric esophagogastric NNP cord-015369-72cjogxz 5261 17 junction junction NN cord-015369-72cjogxz 5261 18 . . . cord-015369-72cjogxz 5262 1 Endoscopically endoscopically RB cord-015369-72cjogxz 5262 2 , , , cord-015369-72cjogxz 5262 3 2.5 2.5 CD cord-015369-72cjogxz 5262 4 % % NN cord-015369-72cjogxz 5262 5 had have VBD cord-015369-72cjogxz 5262 6 candida candida NN cord-015369-72cjogxz 5262 7 - - HYPH cord-015369-72cjogxz 5262 8 esophagitis esophagitis NN cord-015369-72cjogxz 5262 9 , , , cord-015369-72cjogxz 5262 10 5 5 CD cord-015369-72cjogxz 5262 11 % % NN cord-015369-72cjogxz 5262 12 showed show VBD cord-015369-72cjogxz 5262 13 signs sign NNS cord-015369-72cjogxz 5262 14 of of IN cord-015369-72cjogxz 5262 15 a a DT cord-015369-72cjogxz 5262 16 GERD GERD NNP cord-015369-72cjogxz 5262 17 I I NNP cord-015369-72cjogxz 5262 18 , , , cord-015369-72cjogxz 5262 19 92.5 92.5 CD cord-015369-72cjogxz 5262 20 % % NN cord-015369-72cjogxz 5262 21 had have VBD cord-015369-72cjogxz 5262 22 a a DT cord-015369-72cjogxz 5262 23 macroscopically macroscopically RB cord-015369-72cjogxz 5262 24 insuspect insuspect JJ cord-015369-72cjogxz 5262 25 esophageal esophageal JJ cord-015369-72cjogxz 5262 26 mucosa mucosa NN cord-015369-72cjogxz 5262 27 . . . cord-015369-72cjogxz 5263 1 Histologically histologically RB cord-015369-72cjogxz 5263 2 , , , cord-015369-72cjogxz 5263 3 53 53 CD cord-015369-72cjogxz 5263 4 % % NN cord-015369-72cjogxz 5263 5 showed show VBD cord-015369-72cjogxz 5263 6 a a DT cord-015369-72cjogxz 5263 7 mild mild JJ cord-015369-72cjogxz 5263 8 chronic chronic JJ cord-015369-72cjogxz 5263 9 inflammation inflammation NN cord-015369-72cjogxz 5263 10 . . . cord-015369-72cjogxz 5264 1 Manometry Manometry NNP cord-015369-72cjogxz 5264 2 demonstrated demonstrate VBD cord-015369-72cjogxz 5264 3 distinct distinct JJ cord-015369-72cjogxz 5264 4 hypomotility hypomotility NN cord-015369-72cjogxz 5264 5 of of IN cord-015369-72cjogxz 5264 6 the the DT cord-015369-72cjogxz 5264 7 esophagus esophagus NN cord-015369-72cjogxz 5264 8 in in IN cord-015369-72cjogxz 5264 9 all all DT cord-015369-72cjogxz 5264 10 cases case NNS cord-015369-72cjogxz 5264 11 , , , cord-015369-72cjogxz 5264 12 yet yet CC cord-015369-72cjogxz 5264 13 no no DT cord-015369-72cjogxz 5264 14 elevated elevated JJ cord-015369-72cjogxz 5264 15 pressure pressure NN cord-015369-72cjogxz 5264 16 of of IN cord-015369-72cjogxz 5264 17 the the DT cord-015369-72cjogxz 5264 18 lower low JJR cord-015369-72cjogxz 5264 19 sphincter sphincter NN cord-015369-72cjogxz 5264 20 ; ; : cord-015369-72cjogxz 5264 21 pH pH NNP cord-015369-72cjogxz 5264 22 - - HYPH cord-015369-72cjogxz 5264 23 metry metry NNP cord-015369-72cjogxz 5264 24 showed show VBD cord-015369-72cjogxz 5264 25 moderate moderate JJ cord-015369-72cjogxz 5264 26 reflux reflux NN cord-015369-72cjogxz 5264 27 in in IN cord-015369-72cjogxz 5264 28 46 46 CD cord-015369-72cjogxz 5264 29 % % NN cord-015369-72cjogxz 5264 30 . . . cord-015369-72cjogxz 5265 1 Conclusions conclusion NNS cord-015369-72cjogxz 5265 2 . . . cord-015369-72cjogxz 5266 1 Transthoracic Transthoracic NNP cord-015369-72cjogxz 5266 2 cardiomyotomy cardiomyotomy NN cord-015369-72cjogxz 5266 3 is be VBZ cord-015369-72cjogxz 5266 4 a a DT cord-015369-72cjogxz 5266 5 valid valid JJ cord-015369-72cjogxz 5266 6 method method NN cord-015369-72cjogxz 5266 7 for for IN cord-015369-72cjogxz 5266 8 the the DT cord-015369-72cjogxz 5266 9 treatment treatment NN cord-015369-72cjogxz 5266 10 of of IN cord-015369-72cjogxz 5266 11 achalasia achalasia NNP cord-015369-72cjogxz 5266 12 , , , cord-015369-72cjogxz 5266 13 but but CC cord-015369-72cjogxz 5266 14 it -PRON- PRP cord-015369-72cjogxz 5266 15 will will MD cord-015369-72cjogxz 5266 16 not not RB cord-015369-72cjogxz 5266 17 improve improve VB cord-015369-72cjogxz 5266 18 the the DT cord-015369-72cjogxz 5266 19 esophageal esophageal JJ cord-015369-72cjogxz 5266 20 motility motility NN cord-015369-72cjogxz 5266 21 , , , cord-015369-72cjogxz 5266 22 which which WDT cord-015369-72cjogxz 5266 23 slowly slowly RB cord-015369-72cjogxz 5266 24 deterioriates deterioriate VBZ cord-015369-72cjogxz 5266 25 in in IN cord-015369-72cjogxz 5266 26 these these DT cord-015369-72cjogxz 5266 27 cases case NNS cord-015369-72cjogxz 5266 28 . . . cord-015369-72cjogxz 5267 1 The the DT cord-015369-72cjogxz 5267 2 patient patient NN cord-015369-72cjogxz 5267 3 's 's POS cord-015369-72cjogxz 5267 4 subjective subjective JJ cord-015369-72cjogxz 5267 5 assessment assessment NN cord-015369-72cjogxz 5267 6 of of IN cord-015369-72cjogxz 5267 7 the the DT cord-015369-72cjogxz 5267 8 postoperative postoperative JJ cord-015369-72cjogxz 5267 9 result result NN cord-015369-72cjogxz 5267 10 was be VBD cord-015369-72cjogxz 5267 11 positive positive JJ cord-015369-72cjogxz 5267 12 in in IN cord-015369-72cjogxz 5267 13 the the DT cord-015369-72cjogxz 5267 14 majority majority NN cord-015369-72cjogxz 5267 15 of of IN cord-015369-72cjogxz 5267 16 cases case NNS cord-015369-72cjogxz 5267 17 . . . cord-015369-72cjogxz 5268 1 Although although IN cord-015369-72cjogxz 5268 2 fundoplication fundoplication NN cord-015369-72cjogxz 5268 3 was be VBD cord-015369-72cjogxz 5268 4 not not RB cord-015369-72cjogxz 5268 5 done do VBN cord-015369-72cjogxz 5268 6 in in IN cord-015369-72cjogxz 5268 7 any any DT cord-015369-72cjogxz 5268 8 of of IN cord-015369-72cjogxz 5268 9 these these DT cord-015369-72cjogxz 5268 10 patients patient NNS cord-015369-72cjogxz 5268 11 , , , cord-015369-72cjogxz 5268 12 none none NN cord-015369-72cjogxz 5268 13 of of IN cord-015369-72cjogxz 5268 14 them -PRON- PRP cord-015369-72cjogxz 5268 15 showed show VBD cord-015369-72cjogxz 5268 16 signs sign NNS cord-015369-72cjogxz 5268 17 of of IN cord-015369-72cjogxz 5268 18 clinically clinically RB cord-015369-72cjogxz 5268 19 relevant relevant JJ cord-015369-72cjogxz 5268 20 reflux reflux NN cord-015369-72cjogxz 5268 21 . . . cord-015369-72cjogxz 5269 1 Methods method NNS cord-015369-72cjogxz 5269 2 . . . cord-015369-72cjogxz 5270 1 Review review VB cord-015369-72cjogxz 5270 2 on on IN cord-015369-72cjogxz 5270 3 the the DT cord-015369-72cjogxz 5270 4 dilated dilated JJ cord-015369-72cjogxz 5270 5 end end NN cord-015369-72cjogxz 5270 6 stage stage NN cord-015369-72cjogxz 5270 7 esophagus esophagus NN cord-015369-72cjogxz 5270 8 . . . cord-015369-72cjogxz 5271 1 Results result NNS cord-015369-72cjogxz 5271 2 . . . cord-015369-72cjogxz 5272 1 Anatomy anatomy NN cord-015369-72cjogxz 5272 2 and and CC cord-015369-72cjogxz 5272 3 biopsy biopsy NN cord-015369-72cjogxz 5272 4 studies study NNS cord-015369-72cjogxz 5272 5 in in IN cord-015369-72cjogxz 5272 6 GERD GERD NNP cord-015369-72cjogxz 5272 7 patients patient NNS cord-015369-72cjogxz 5272 8 revealed reveal VBD cord-015369-72cjogxz 5272 9 the the DT cord-015369-72cjogxz 5272 10 presence presence NN cord-015369-72cjogxz 5272 11 of of IN cord-015369-72cjogxz 5272 12 CLE CLE NNP cord-015369-72cjogxz 5272 13 within within IN cord-015369-72cjogxz 5272 14 the the DT cord-015369-72cjogxz 5272 15 proximal proximal JJ cord-015369-72cjogxz 5272 16 portion portion NN cord-015369-72cjogxz 5272 17 of of IN cord-015369-72cjogxz 5272 18 the the DT cord-015369-72cjogxz 5272 19 endoscopically endoscopically RB cord-015369-72cjogxz 5272 20 visible visible JJ cord-015369-72cjogxz 5272 21 gastric gastric JJ cord-015369-72cjogxz 5272 22 type type NN cord-015369-72cjogxz 5272 23 folds fold VBZ cord-015369-72cjogxz 5272 24 over over IN cord-015369-72cjogxz 5272 25 a a DT cord-015369-72cjogxz 5272 26 length length NN cord-015369-72cjogxz 5272 27 ranging range VBG cord-015369-72cjogxz 5272 28 from from IN cord-015369-72cjogxz 5272 29 < < XX cord-015369-72cjogxz 5272 30 0.5 0.5 CD cord-015369-72cjogxz 5272 31 to to IN cord-015369-72cjogxz 5272 32 2.8 2.8 CD cord-015369-72cjogxz 5272 33 cm cm NNS cord-015369-72cjogxz 5272 34 , , , cord-015369-72cjogxz 5272 35 where where WRB cord-015369-72cjogxz 5272 36 CLE CLE NNP cord-015369-72cjogxz 5272 37 ( ( -LRB- cord-015369-72cjogxz 5272 38 cardiac cardiac JJ cord-015369-72cjogxz 5272 39 mucosa mucosa NN cord-015369-72cjogxz 5272 40 AE AE NNP cord-015369-72cjogxz 5272 41 intestinal intestinal JJ cord-015369-72cjogxz 5272 42 metaplasia metaplasia NN cord-015369-72cjogxz 5272 43 , , , cord-015369-72cjogxz 5272 44 oxyntocardiac oxyntocardiac NN cord-015369-72cjogxz 5272 45 mucosa mucosa NN cord-015369-72cjogxz 5272 46 ) ) -RRB- cord-015369-72cjogxz 5272 47 transitioned transition VBD cord-015369-72cjogxz 5272 48 towards towards IN cord-015369-72cjogxz 5272 49 the the DT cord-015369-72cjogxz 5272 50 oxyntic oxyntic JJ cord-015369-72cjogxz 5272 51 mucosa mucosa NN cord-015369-72cjogxz 5272 52 of of IN cord-015369-72cjogxz 5272 53 the the DT cord-015369-72cjogxz 5272 54 proximal proximal JJ cord-015369-72cjogxz 5272 55 stomach stomach NN cord-015369-72cjogxz 5272 56 , , , cord-015369-72cjogxz 5272 57 irrespective irrespective RB cord-015369-72cjogxz 5272 58 of of IN cord-015369-72cjogxz 5272 59 the the DT cord-015369-72cjogxz 5272 60 presence presence NN cord-015369-72cjogxz 5272 61 or or CC cord-015369-72cjogxz 5272 62 absence absence NN cord-015369-72cjogxz 5272 63 of of IN cord-015369-72cjogxz 5272 64 endoscopically endoscopically RB cord-015369-72cjogxz 5272 65 visible visible JJ cord-015369-72cjogxz 5272 66 CLE cle NN cord-015369-72cjogxz 5272 67 within within IN cord-015369-72cjogxz 5272 68 the the DT cord-015369-72cjogxz 5272 69 tubular tubular JJ cord-015369-72cjogxz 5272 70 esophagus esophagu NNS cord-015369-72cjogxz 5272 71 . . . cord-015369-72cjogxz 5273 1 Fusion fusion NN cord-015369-72cjogxz 5273 2 of of IN cord-015369-72cjogxz 5273 3 histopathology histopathology NN cord-015369-72cjogxz 5273 4 and and CC cord-015369-72cjogxz 5273 5 function function NN cord-015369-72cjogxz 5273 6 test test NN cord-015369-72cjogxz 5273 7 data datum NNS cord-015369-72cjogxz 5273 8 indicated indicate VBD cord-015369-72cjogxz 5273 9 that that IN cord-015369-72cjogxz 5273 10 this this DT cord-015369-72cjogxz 5273 11 condition condition NN cord-015369-72cjogxz 5273 12 results result VBZ cord-015369-72cjogxz 5273 13 from from IN cord-015369-72cjogxz 5273 14 a a DT cord-015369-72cjogxz 5273 15 mechanism mechanism NN cord-015369-72cjogxz 5273 16 involving involve VBG cord-015369-72cjogxz 5273 17 gastric gastric JJ cord-015369-72cjogxz 5273 18 distention distention NN cord-015369-72cjogxz 5273 19 induced induce VBN cord-015369-72cjogxz 5273 20 damage damage NN cord-015369-72cjogxz 5273 21 of of IN cord-015369-72cjogxz 5273 22 the the DT cord-015369-72cjogxz 5273 23 lower low JJR cord-015369-72cjogxz 5273 24 esophageal esophageal JJ cord-015369-72cjogxz 5273 25 sphincter sphincter NN cord-015369-72cjogxz 5273 26 causing cause VBG cord-015369-72cjogxz 5273 27 reflux reflux NN cord-015369-72cjogxz 5273 28 , , , cord-015369-72cjogxz 5273 29 damage damage NN cord-015369-72cjogxz 5273 30 and and CC cord-015369-72cjogxz 5273 31 columnar columnar JJ cord-015369-72cjogxz 5273 32 metaplasia metaplasia NN cord-015369-72cjogxz 5273 33 with with IN cord-015369-72cjogxz 5273 34 proximal proximal JJ cord-015369-72cjogxz 5273 35 dislocation dislocation NN cord-015369-72cjogxz 5273 36 of of IN cord-015369-72cjogxz 5273 37 the the DT cord-015369-72cjogxz 5273 38 squamocolumnar squamocolumnar NNP cord-015369-72cjogxz 5273 39 junction junction NNP cord-015369-72cjogxz 5273 40 . . . cord-015369-72cjogxz 5274 1 Loss loss NN cord-015369-72cjogxz 5274 2 of of IN cord-015369-72cjogxz 5274 3 sphincter sphincter NN cord-015369-72cjogxz 5274 4 function function NN cord-015369-72cjogxz 5274 5 causes cause VBZ cord-015369-72cjogxz 5274 6 gastric gastric JJ cord-015369-72cjogxz 5274 7 type type NN cord-015369-72cjogxz 5274 8 folding folding NN cord-015369-72cjogxz 5274 9 of of IN cord-015369-72cjogxz 5274 10 the the DT cord-015369-72cjogxz 5274 11 CLE CLE NNP cord-015369-72cjogxz 5274 12 thus thus RB cord-015369-72cjogxz 5274 13 giving give VBG cord-015369-72cjogxz 5274 14 it -PRON- PRP cord-015369-72cjogxz 5274 15 a a DT cord-015369-72cjogxz 5274 16 gastric gastric JJ cord-015369-72cjogxz 5274 17 type type NN cord-015369-72cjogxz 5274 18 appearance appearance NN cord-015369-72cjogxz 5274 19 during during IN cord-015369-72cjogxz 5274 20 endoscopy endoscopy NN cord-015369-72cjogxz 5274 21 . . . cord-015369-72cjogxz 5275 1 This this DT cord-015369-72cjogxz 5275 2 is be VBZ cord-015369-72cjogxz 5275 3 the the DT cord-015369-72cjogxz 5275 4 dilated dilated JJ cord-015369-72cjogxz 5275 5 end end NN cord-015369-72cjogxz 5275 6 stage stage NN cord-015369-72cjogxz 5275 7 esophagus esophagus NN cord-015369-72cjogxz 5275 8 , , , cord-015369-72cjogxz 5275 9 which which WDT cord-015369-72cjogxz 5275 10 is be VBZ cord-015369-72cjogxz 5275 11 frequently frequently RB cord-015369-72cjogxz 5275 12 taken take VBN cord-015369-72cjogxz 5275 13 for for IN cord-015369-72cjogxz 5275 14 hiatal hiatal JJ cord-015369-72cjogxz 5275 15 hernia hernia NN cord-015369-72cjogxz 5275 16 during during IN cord-015369-72cjogxz 5275 17 endoscopy endoscopy NN cord-015369-72cjogxz 5275 18 and and CC cord-015369-72cjogxz 5275 19 may may MD cord-015369-72cjogxz 5275 20 cause cause VB cord-015369-72cjogxz 5275 21 the the DT cord-015369-72cjogxz 5275 22 formation formation NN cord-015369-72cjogxz 5275 23 of of IN cord-015369-72cjogxz 5275 24 the the DT cord-015369-72cjogxz 5275 25 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 5275 26 of of IN cord-015369-72cjogxz 5275 27 the the DT cord-015369-72cjogxz 5275 28 cardia cardia NNP cord-015369-72cjogxz 5275 29 ( ( -LRB- cord-015369-72cjogxz 5275 30 Siewert siewert JJ cord-015369-72cjogxz 5275 31 type type NN cord-015369-72cjogxz 5275 32 II II NNP cord-015369-72cjogxz 5275 33 ) ) -RRB- cord-015369-72cjogxz 5275 34 . . . cord-015369-72cjogxz 5276 1 Conclusions conclusion NNS cord-015369-72cjogxz 5276 2 . . . cord-015369-72cjogxz 5277 1 In in IN cord-015369-72cjogxz 5277 2 GERD GERD NNP cord-015369-72cjogxz 5277 3 patients patient NNS cord-015369-72cjogxz 5277 4 , , , cord-015369-72cjogxz 5277 5 endoscopy endoscopy NN cord-015369-72cjogxz 5277 6 without without IN cord-015369-72cjogxz 5277 7 biopsy biopsy NN cord-015369-72cjogxz 5277 8 sampling sampling NN cord-015369-72cjogxz 5277 9 of of IN cord-015369-72cjogxz 5277 10 the the DT cord-015369-72cjogxz 5277 11 proximal proximal JJ cord-015369-72cjogxz 5277 12 portion portion NN cord-015369-72cjogxz 5277 13 of of IN cord-015369-72cjogxz 5277 14 the the DT cord-015369-72cjogxz 5277 15 endoscopically endoscopically RB cord-015369-72cjogxz 5277 16 visible visible JJ cord-015369-72cjogxz 5277 17 gastric gastric JJ cord-015369-72cjogxz 5277 18 type type NN cord-015369-72cjogxz 5277 19 folds fold NNS cord-015369-72cjogxz 5277 20 misses miss VBZ cord-015369-72cjogxz 5277 21 the the DT cord-015369-72cjogxz 5277 22 dilated dilated JJ cord-015369-72cjogxz 5277 23 end end NN cord-015369-72cjogxz 5277 24 stage stage NN cord-015369-72cjogxz 5277 25 esophagus esophagus NN cord-015369-72cjogxz 5277 26 . . . cord-015369-72cjogxz 5278 1 Differentiation differentiation NN cord-015369-72cjogxz 5278 2 of of IN cord-015369-72cjogxz 5278 3 the the DT cord-015369-72cjogxz 5278 4 dilated dilated JJ cord-015369-72cjogxz 5278 5 end end NN cord-015369-72cjogxz 5278 6 stage stage NN cord-015369-72cjogxz 5278 7 esophagus esophagus NN cord-015369-72cjogxz 5278 8 from from IN cord-015369-72cjogxz 5278 9 proximal proximal JJ cord-015369-72cjogxz 5278 10 stomach stomach NN cord-015369-72cjogxz 5278 11 ( ( -LRB- cord-015369-72cjogxz 5278 12 hernia hernia NN cord-015369-72cjogxz 5278 13 ) ) -RRB- cord-015369-72cjogxz 5278 14 requires require VBZ cord-015369-72cjogxz 5278 15 the the DT cord-015369-72cjogxz 5278 16 histopathology histopathology NN cord-015369-72cjogxz 5278 17 of of IN cord-015369-72cjogxz 5278 18 biopsies biopsy NNS cord-015369-72cjogxz 5278 19 . . . cord-015369-72cjogxz 5279 1 Background background NN cord-015369-72cjogxz 5279 2 . . . cord-015369-72cjogxz 5280 1 Differences difference NNS cord-015369-72cjogxz 5280 2 in in IN cord-015369-72cjogxz 5280 3 the the DT cord-015369-72cjogxz 5280 4 prevalence prevalence NN cord-015369-72cjogxz 5280 5 of of IN cord-015369-72cjogxz 5280 6 the the DT cord-015369-72cjogxz 5280 7 morphologic morphologic JJ cord-015369-72cjogxz 5280 8 manifestations manifestation NNS cord-015369-72cjogxz 5280 9 of of IN cord-015369-72cjogxz 5280 10 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 5280 11 reflux reflux NN cord-015369-72cjogxz 5280 12 disease disease NN cord-015369-72cjogxz 5280 13 ( ( -LRB- cord-015369-72cjogxz 5280 14 GERD GERD NNP cord-015369-72cjogxz 5280 15 ) ) -RRB- cord-015369-72cjogxz 5280 16 , , , cord-015369-72cjogxz 5280 17 columnar columnar JJ cord-015369-72cjogxz 5280 18 lined line VBN cord-015369-72cjogxz 5280 19 esophagus esophagu NNS cord-015369-72cjogxz 5280 20 ( ( -LRB- cord-015369-72cjogxz 5280 21 CLE CLE NNP cord-015369-72cjogxz 5280 22 ) ) -RRB- cord-015369-72cjogxz 5280 23 and and CC cord-015369-72cjogxz 5280 24 Barrett Barrett NNP cord-015369-72cjogxz 5280 25 's 's POS cord-015369-72cjogxz 5280 26 esophagus esophagu NNS cord-015369-72cjogxz 5280 27 ( ( -LRB- cord-015369-72cjogxz 5281 1 BE be VB cord-015369-72cjogxz 5281 2 ; ; : cord-015369-72cjogxz 5281 3 0.5 0.5 CD cord-015369-72cjogxz 5281 4 % % NN cord-015369-72cjogxz 5281 5 annual annual JJ cord-015369-72cjogxz 5281 6 cancer cancer NN cord-015369-72cjogxz 5281 7 risk risk NN cord-015369-72cjogxz 5281 8 ) ) -RRB- cord-015369-72cjogxz 5281 9 in in IN cord-015369-72cjogxz 5281 10 those those DT cord-015369-72cjogxz 5281 11 with with IN cord-015369-72cjogxz 5281 12 and and CC cord-015369-72cjogxz 5281 13 without without IN cord-015369-72cjogxz 5281 14 GERD GERD NNP cord-015369-72cjogxz 5281 15 symptoms symptom NNS cord-015369-72cjogxz 5281 16 is be VBZ cord-015369-72cjogxz 5281 17 not not RB cord-015369-72cjogxz 5281 18 known know VBN cord-015369-72cjogxz 5281 19 . . . cord-015369-72cjogxz 5282 1 Methods method NNS cord-015369-72cjogxz 5282 2 . . . cord-015369-72cjogxz 5283 1 Esophagogastroduodenoscopy Esophagogastroduodenoscopy NNP cord-015369-72cjogxz 5283 2 ( ( -LRB- cord-015369-72cjogxz 5283 3 EGD EGD NNP cord-015369-72cjogxz 5283 4 ) ) -RRB- cord-015369-72cjogxz 5283 5 with with IN cord-015369-72cjogxz 5283 6 multi multi JJ cord-015369-72cjogxz 5283 7 level level NN cord-015369-72cjogxz 5283 8 biopsies biopsy NNS cord-015369-72cjogxz 5283 9 from from IN cord-015369-72cjogxz 5283 10 the the DT cord-015369-72cjogxz 5283 11 esophagogastric esophagogastric NNP cord-015369-72cjogxz 5283 12 junction junction NNP cord-015369-72cjogxz 5283 13 ( ( -LRB- cord-015369-72cjogxz 5283 14 1.0 1.0 CD cord-015369-72cjogxz 5283 15 cm cm NNS cord-015369-72cjogxz 5283 16 , , , cord-015369-72cjogxz 5283 17 0.5 0.5 CD cord-015369-72cjogxz 5283 18 cm cm NNS cord-015369-72cjogxz 5283 19 above above RB cord-015369-72cjogxz 5283 20 , , , cord-015369-72cjogxz 5283 21 at at IN cord-015369-72cjogxz 5283 22 and and CC cord-015369-72cjogxz 5283 23 0.5 0.5 CD cord-015369-72cjogxz 5283 24 cm cm NNS cord-015369-72cjogxz 5283 25 , , , cord-015369-72cjogxz 5283 26 1.0 1.0 CD cord-015369-72cjogxz 5283 27 cm cm NNS cord-015369-72cjogxz 5283 28 distal distal JJ cord-015369-72cjogxz 5283 29 to to IN cord-015369-72cjogxz 5283 30 the the DT cord-015369-72cjogxz 5283 31 level level NN cord-015369-72cjogxz 5283 32 of of IN cord-015369-72cjogxz 5283 33 the the DT cord-015369-72cjogxz 5283 34 rise rise NN cord-015369-72cjogxz 5283 35 of of IN cord-015369-72cjogxz 5283 36 the the DT cord-015369-72cjogxz 5283 37 gastric gastric JJ cord-015369-72cjogxz 5283 38 folds fold NNS cord-015369-72cjogxz 5283 39 ) ) -RRB- cord-015369-72cjogxz 5283 40 was be VBD cord-015369-72cjogxz 5283 41 prospectively prospectively RB cord-015369-72cjogxz 5283 42 conducted conduct VBN cord-015369-72cjogxz 5283 43 in in IN cord-015369-72cjogxz 5283 44 asymptomatic asymptomatic JJ cord-015369-72cjogxz 5283 45 patients patient NNS cord-015369-72cjogxz 5283 46 ( ( -LRB- cord-015369-72cjogxz 5283 47 controls control NNS cord-015369-72cjogxz 5283 48 ; ; : cord-015369-72cjogxz 5283 49 n n NN cord-015369-72cjogxz 5283 50 ¼ ¼ NNP cord-015369-72cjogxz 5283 51 81 81 CD cord-015369-72cjogxz 5283 52 ; ; : cord-015369-72cjogxz 5283 53 25.5 25.5 CD cord-015369-72cjogxz 5283 54 % % NN cord-015369-72cjogxz 5283 55 ) ) -RRB- cord-015369-72cjogxz 5283 56 and and CC cord-015369-72cjogxz 5283 57 GERD GERD NNP cord-015369-72cjogxz 5283 58 patients patient NNS cord-015369-72cjogxz 5283 59 ( ( -LRB- cord-015369-72cjogxz 5283 60 n n CC cord-015369-72cjogxz 5283 61 ¼ ¼ NNP cord-015369-72cjogxz 5283 62 237 237 CD cord-015369-72cjogxz 5283 63 ; ; : cord-015369-72cjogxz 5283 64 74.5 74.5 CD cord-015369-72cjogxz 5283 65 % % NN cord-015369-72cjogxz 5283 66 ) ) -RRB- cord-015369-72cjogxz 5283 67 ; ; : cord-015369-72cjogxz 5283 68 aged age VBN cord-015369-72cjogxz 5283 69 between between IN cord-015369-72cjogxz 5283 70 17 17 CD cord-015369-72cjogxz 5283 71 - - SYM cord-015369-72cjogxz 5283 72 84 84 CD cord-015369-72cjogxz 5283 73 years year NNS cord-015369-72cjogxz 5283 74 ( ( -LRB- cord-015369-72cjogxz 5283 75 50 50 CD cord-015369-72cjogxz 5283 76 AE AE NNP cord-015369-72cjogxz 5283 77 14.6 14.6 CD cord-015369-72cjogxz 5283 78 ) ) -RRB- cord-015369-72cjogxz 5283 79 and and CC cord-015369-72cjogxz 5283 80 55.6 55.6 CD cord-015369-72cjogxz 5283 81 % % NN cord-015369-72cjogxz 5283 82 females female NNS cord-015369-72cjogxz 5283 83 . . . cord-015369-72cjogxz 5284 1 Columnar columnar JJ cord-015369-72cjogxz 5284 2 lining lining NN cord-015369-72cjogxz 5284 3 above above IN cord-015369-72cjogxz 5284 4 the the DT cord-015369-72cjogxz 5284 5 level level NN cord-015369-72cjogxz 5284 6 of of IN cord-015369-72cjogxz 5284 7 the the DT cord-015369-72cjogxz 5284 8 rise rise NN cord-015369-72cjogxz 5284 9 of of IN cord-015369-72cjogxz 5284 10 the the DT cord-015369-72cjogxz 5284 11 gastric gastric JJ cord-015369-72cjogxz 5284 12 folds fold NNS cord-015369-72cjogxz 5284 13 was be VBD cord-015369-72cjogxz 5284 14 categorized categorize VBN cord-015369-72cjogxz 5284 15 as as IN cord-015369-72cjogxz 5284 16 endoscopically endoscopically RB cord-015369-72cjogxz 5284 17 visible visible JJ cord-015369-72cjogxz 5284 18 CLE cle NN cord-015369-72cjogxz 5284 19 ( ( -LRB- cord-015369-72cjogxz 5284 20 CLEv CLEv NNP cord-015369-72cjogxz 5284 21 ) ) -RRB- cord-015369-72cjogxz 5284 22 . . . cord-015369-72cjogxz 5285 1 Histopathology Histopathology NNP cord-015369-72cjogxz 5285 2 of of IN cord-015369-72cjogxz 5285 3 CLE CLE NNP cord-015369-72cjogxz 5285 4 included include VBD cord-015369-72cjogxz 5285 5 cardiac cardiac JJ cord-015369-72cjogxz 5285 6 mucosa mucosa NN cord-015369-72cjogxz 5285 7 AE AE NNP cord-015369-72cjogxz 5285 8 intestinal intestinal JJ cord-015369-72cjogxz 5285 9 metaplasia metaplasia NN cord-015369-72cjogxz 5285 10 ( ( -LRB- cord-015369-72cjogxz 5285 11 ¼BE ¼be UH cord-015369-72cjogxz 5285 12 ) ) -RRB- cord-015369-72cjogxz 5285 13 and and CC cord-015369-72cjogxz 5285 14 oxntocardiac oxntocardiac NN cord-015369-72cjogxz 5285 15 mucosa mucosa NN cord-015369-72cjogxz 5285 16 ; ; . cord-015369-72cjogxz 5286 1 squamous squamous JJ cord-015369-72cjogxz 5286 2 epithelium epithelium NN cord-015369-72cjogxz 5286 3 and and CC cord-015369-72cjogxz 5286 4 oxyntic oxyntic JJ cord-015369-72cjogxz 5286 5 mucosa mucosa NN cord-015369-72cjogxz 5286 6 ( ( -LRB- cord-015369-72cjogxz 5286 7 OM OM NNP cord-015369-72cjogxz 5286 8 ) ) -RRB- cord-015369-72cjogxz 5286 9 were be VBD cord-015369-72cjogxz 5286 10 considered consider VBN cord-015369-72cjogxz 5286 11 as as IN cord-015369-72cjogxz 5286 12 normal normal JJ cord-015369-72cjogxz 5286 13 lining lining NN cord-015369-72cjogxz 5286 14 of of IN cord-015369-72cjogxz 5286 15 the the DT cord-015369-72cjogxz 5286 16 esophagus esophagus NN cord-015369-72cjogxz 5286 17 and and CC cord-015369-72cjogxz 5286 18 the the DT cord-015369-72cjogxz 5286 19 proximal proximal JJ cord-015369-72cjogxz 5286 20 stomach stomach NN cord-015369-72cjogxz 5286 21 . . . cord-015369-72cjogxz 5287 1 Prevalence prevalence NN cord-015369-72cjogxz 5287 2 of of IN cord-015369-72cjogxz 5287 3 CLEv clev NN cord-015369-72cjogxz 5287 4 and and CC cord-015369-72cjogxz 5287 5 histopathology histopathology NN cord-015369-72cjogxz 5287 6 proven prove VBN cord-015369-72cjogxz 5287 7 CLE CLE NNP cord-015369-72cjogxz 5287 8 was be VBD cord-015369-72cjogxz 5287 9 compared compare VBN cord-015369-72cjogxz 5287 10 between between IN cord-015369-72cjogxz 5287 11 controls control NNS cord-015369-72cjogxz 5287 12 and and CC cord-015369-72cjogxz 5287 13 GERD GERD NNP cord-015369-72cjogxz 5287 14 patients patient NNS cord-015369-72cjogxz 5287 15 . . . cord-015369-72cjogxz 5288 1 Results result NNS cord-015369-72cjogxz 5288 2 . . . cord-015369-72cjogxz 5289 1 There there EX cord-015369-72cjogxz 5289 2 were be VBD cord-015369-72cjogxz 5289 3 no no DT cord-015369-72cjogxz 5289 4 significant significant JJ cord-015369-72cjogxz 5289 5 age- age- NN cord-015369-72cjogxz 5290 1 , , , cord-015369-72cjogxz 5290 2 gender gender NN cord-015369-72cjogxz 5290 3 - - HYPH cord-015369-72cjogxz 5290 4 differences difference NNS cord-015369-72cjogxz 5290 5 between between IN cord-015369-72cjogxz 5290 6 the the DT cord-015369-72cjogxz 5290 7 groups group NNS cord-015369-72cjogxz 5290 8 ( ( -LRB- cord-015369-72cjogxz 5290 9 p p NN cord-015369-72cjogxz 5290 10 > > XX cord-015369-72cjogxz 5290 11 0.05 0.05 CD cord-015369-72cjogxz 5290 12 ) ) -RRB- cord-015369-72cjogxz 5290 13 . . . cord-015369-72cjogxz 5291 1 Prevalence prevalence NN cord-015369-72cjogxz 5291 2 of of IN cord-015369-72cjogxz 5291 3 CLEv clev NN cord-015369-72cjogxz 5291 4 ( ( -LRB- cord-015369-72cjogxz 5291 5 p p NN cord-015369-72cjogxz 5291 6 ¼ ¼ NNP cord-015369-72cjogxz 5291 7 0.083 0.083 CD cord-015369-72cjogxz 5291 8 ) ) -RRB- cord-015369-72cjogxz 5291 9 , , , cord-015369-72cjogxz 5291 10 histopathology histopathology NN cord-015369-72cjogxz 5291 11 proven prove VBN cord-015369-72cjogxz 5291 12 CLE CLE NNP cord-015369-72cjogxz 5291 13 ( ( -LRB- cord-015369-72cjogxz 5291 14 p p NN cord-015369-72cjogxz 5291 15 > > XX cord-015369-72cjogxz 5291 16 0.999 0.999 CD cord-015369-72cjogxz 5291 17 ) ) -RRB- cord-015369-72cjogxz 5292 1 , , , cord-015369-72cjogxz 5292 2 CLE CLE NNP cord-015369-72cjogxz 5292 3 length length NN cord-015369-72cjogxz 5293 1 ( ( -LRB- cord-015369-72cjogxz 5293 2 p p NN cord-015369-72cjogxz 5293 3 ¼ ¼ NNP cord-015369-72cjogxz 5293 4 0.321 0.321 CD cord-015369-72cjogxz 5293 5 ) ) -RRB- cord-015369-72cjogxz 5294 1 and and CC cord-015369-72cjogxz 5294 2 intestinal intestinal JJ cord-015369-72cjogxz 5294 3 metaplasia metaplasia NN cord-015369-72cjogxz 5295 1 ( ( -LRB- cord-015369-72cjogxz 5295 2 controls control VBZ cord-015369-72cjogxz 5295 3 : : : cord-015369-72cjogxz 5295 4 13.6 13.6 CD cord-015369-72cjogxz 5295 5 % % NN cord-015369-72cjogxz 5295 6 ; ; : cord-015369-72cjogxz 5295 7 GERD GERD NNP cord-015369-72cjogxz 5295 8 : : : cord-015369-72cjogxz 5295 9 20.7 20.7 CD cord-015369-72cjogxz 5295 10 % % NN cord-015369-72cjogxz 5295 11 ; ; : cord-015369-72cjogxz 5295 12 p p NN cord-015369-72cjogxz 5295 13 ¼ ¼ CD cord-015369-72cjogxz 5295 14 0.159 0.159 CD cord-015369-72cjogxz 5295 15 ) ) -RRB- cord-015369-72cjogxz 5295 16 was be VBD cord-015369-72cjogxz 5295 17 indifferent indifferent JJ cord-015369-72cjogxz 5295 18 between between IN cord-015369-72cjogxz 5295 19 controls control NNS cord-015369-72cjogxz 5295 20 and and CC cord-015369-72cjogxz 5295 21 GERD GERD NNP cord-015369-72cjogxz 5295 22 patients patient NNS cord-015369-72cjogxz 5295 23 . . . cord-015369-72cjogxz 5296 1 Dysplasia dysplasia NN cord-015369-72cjogxz 5296 2 and and CC cord-015369-72cjogxz 5296 3 cancer cancer NN cord-015369-72cjogxz 5296 4 have have VBP cord-015369-72cjogxz 5296 5 not not RB cord-015369-72cjogxz 5296 6 been be VBN cord-015369-72cjogxz 5296 7 assessed assess VBN cord-015369-72cjogxz 5296 8 . . . cord-015369-72cjogxz 5297 1 Conclusions conclusion NNS cord-015369-72cjogxz 5297 2 . . . cord-015369-72cjogxz 5298 1 The the DT cord-015369-72cjogxz 5298 2 prevalence prevalence NN cord-015369-72cjogxz 5298 3 of of IN cord-015369-72cjogxz 5298 4 CLE CLE NNP cord-015369-72cjogxz 5298 5 and and CC cord-015369-72cjogxz 5298 6 Barrett Barrett NNP cord-015369-72cjogxz 5298 7 's 's POS cord-015369-72cjogxz 5298 8 esophagus esophagus NN cord-015369-72cjogxz 5298 9 was be VBD cord-015369-72cjogxz 5298 10 comparable comparable JJ cord-015369-72cjogxz 5298 11 in in IN cord-015369-72cjogxz 5298 12 patients patient NNS cord-015369-72cjogxz 5298 13 with with IN cord-015369-72cjogxz 5298 14 and and CC cord-015369-72cjogxz 5298 15 without without IN cord-015369-72cjogxz 5298 16 GERD GERD NNP cord-015369-72cjogxz 5298 17 symptoms symptom NNS cord-015369-72cjogxz 5298 18 . . . cord-015369-72cjogxz 5299 1 Our -PRON- PRP$ cord-015369-72cjogxz 5299 2 findings finding NNS cord-015369-72cjogxz 5299 3 may may MD cord-015369-72cjogxz 5299 4 justify justify VB cord-015369-72cjogxz 5299 5 to to TO cord-015369-72cjogxz 5299 6 consider consider VB cord-015369-72cjogxz 5299 7 screening screen VBG cord-015369-72cjogxz 5299 8 endoscopy endoscopy NN cord-015369-72cjogxz 5299 9 for for IN cord-015369-72cjogxz 5299 10 Barrett Barrett NNP cord-015369-72cjogxz 5299 11 's 's POS cord-015369-72cjogxz 5299 12 esophagus esophagus NN cord-015369-72cjogxz 5299 13 . . . cord-015369-72cjogxz 5300 1 The the DT cord-015369-72cjogxz 5300 2 aim aim NN cord-015369-72cjogxz 5300 3 was be VBD cord-015369-72cjogxz 5300 4 to to TO cord-015369-72cjogxz 5300 5 evaluate evaluate VB cord-015369-72cjogxz 5300 6 long long JJ cord-015369-72cjogxz 5300 7 - - HYPH cord-015369-72cjogxz 5300 8 term term NN cord-015369-72cjogxz 5300 9 results result NNS cord-015369-72cjogxz 5300 10 of of IN cord-015369-72cjogxz 5300 11 revascularization revascularization NN cord-015369-72cjogxz 5300 12 in in IN cord-015369-72cjogxz 5300 13 significant significant JJ cord-015369-72cjogxz 5300 14 coronary coronary JJ cord-015369-72cjogxz 5300 15 artery artery NN cord-015369-72cjogxz 5300 16 disease disease NN cord-015369-72cjogxz 5300 17 ( ( -LRB- cord-015369-72cjogxz 5300 18 CAV CAV NNP cord-015369-72cjogxz 5300 19 ) ) -RRB- cord-015369-72cjogxz 5300 20 . . . cord-015369-72cjogxz 5301 1 The the DT cord-015369-72cjogxz 5301 2 group group NN cord-015369-72cjogxz 5301 3 contained contain VBD cord-015369-72cjogxz 5301 4 55 55 CD cord-015369-72cjogxz 5301 5 patients patient NNS cord-015369-72cjogxz 5301 6 ( ( -LRB- cord-015369-72cjogxz 5301 7 89 89 CD cord-015369-72cjogxz 5301 8 % % NN cord-015369-72cjogxz 5301 9 male male NN cord-015369-72cjogxz 5301 10 ) ) -RRB- cord-015369-72cjogxz 5301 11 . . . cord-015369-72cjogxz 5302 1 The the DT cord-015369-72cjogxz 5302 2 mean mean JJ cord-015369-72cjogxz 5302 3 HTX HTX NNP cord-015369-72cjogxz 5302 4 age age NN cord-015369-72cjogxz 5302 5 was be VBD cord-015369-72cjogxz 5302 6 47 47 CD cord-015369-72cjogxz 5302 7 AE AE NNP cord-015369-72cjogxz 5302 8 10 10 CD cord-015369-72cjogxz 5302 9 yrs yrs NN cord-015369-72cjogxz 5302 10 ( ( -LRB- cord-015369-72cjogxz 5302 11 range range NN cord-015369-72cjogxz 5302 12 from from IN cord-015369-72cjogxz 5302 13 20 20 CD cord-015369-72cjogxz 5302 14 to to TO cord-015369-72cjogxz 5302 15 65 65 CD cord-015369-72cjogxz 5302 16 yrs yrs NN cord-015369-72cjogxz 5302 17 ) ) -RRB- cord-015369-72cjogxz 5302 18 . . . cord-015369-72cjogxz 5303 1 The the DT cord-015369-72cjogxz 5303 2 mean mean JJ cord-015369-72cjogxz 5303 3 donor donor NN cord-015369-72cjogxz 5303 4 age age NN cord-015369-72cjogxz 5303 5 was be VBD cord-015369-72cjogxz 5303 6 33 33 CD cord-015369-72cjogxz 5303 7 AE AE NNP cord-015369-72cjogxz 5303 8 11 11 CD cord-015369-72cjogxz 5303 9 years year NNS cord-015369-72cjogxz 5303 10 . . . cord-015369-72cjogxz 5304 1 The the DT cord-015369-72cjogxz 5304 2 mean mean JJ cord-015369-72cjogxz 5304 3 follow follow NN cord-015369-72cjogxz 5304 4 - - HYPH cord-015369-72cjogxz 5304 5 up up NN cord-015369-72cjogxz 5304 6 time time NN cord-015369-72cjogxz 5304 7 after after IN cord-015369-72cjogxz 5304 8 revascularization revascularization NN cord-015369-72cjogxz 5304 9 was be VBD cord-015369-72cjogxz 5304 10 72 72 CD cord-015369-72cjogxz 5304 11 AE AE NNP cord-015369-72cjogxz 5304 12 36 36 CD cord-015369-72cjogxz 5304 13 months month NNS cord-015369-72cjogxz 5304 14 . . . cord-015369-72cjogxz 5305 1 The the DT cord-015369-72cjogxz 5305 2 cumulative cumulative JJ cord-015369-72cjogxz 5305 3 incidence incidence NN cord-015369-72cjogxz 5305 4 of of IN cord-015369-72cjogxz 5305 5 significant significant JJ cord-015369-72cjogxz 5305 6 focal focal JJ cord-015369-72cjogxz 5305 7 CAV CAV NNP cord-015369-72cjogxz 5305 8 was be VBD cord-015369-72cjogxz 5305 9 5 5 CD cord-015369-72cjogxz 5305 10 % % NN cord-015369-72cjogxz 5305 11 . . . cord-015369-72cjogxz 5306 1 The the DT cord-015369-72cjogxz 5306 2 mean mean JJ cord-015369-72cjogxz 5306 3 time time NN cord-015369-72cjogxz 5306 4 to to IN cord-015369-72cjogxz 5306 5 development development NN cord-015369-72cjogxz 5306 6 of of IN cord-015369-72cjogxz 5306 7 significant significant JJ cord-015369-72cjogxz 5306 8 focal focal JJ cord-015369-72cjogxz 5306 9 CAV CAV NNP cord-015369-72cjogxz 5306 10 was be VBD cord-015369-72cjogxz 5306 11 92 92 CD cord-015369-72cjogxz 5306 12 AE AE NNP cord-015369-72cjogxz 5306 13 36 36 CD cord-015369-72cjogxz 5306 14 months month NNS cord-015369-72cjogxz 5306 15 ( ( -LRB- cord-015369-72cjogxz 5306 16 range range VBP cord-015369-72cjogxz 5306 17 from from IN cord-015369-72cjogxz 5306 18 2 2 CD cord-015369-72cjogxz 5306 19 months month NNS cord-015369-72cjogxz 5306 20 to to IN cord-015369-72cjogxz 5306 21 16 16 CD cord-015369-72cjogxz 5306 22 years year NNS cord-015369-72cjogxz 5306 23 ) ) -RRB- cord-015369-72cjogxz 5306 24 . . . cord-015369-72cjogxz 5307 1 A a DT cord-015369-72cjogxz 5307 2 total total NN cord-015369-72cjogxz 5307 3 of of IN cord-015369-72cjogxz 5307 4 164 164 CD cord-015369-72cjogxz 5307 5 lesions lesion NNS cord-015369-72cjogxz 5307 6 were be VBD cord-015369-72cjogxz 5307 7 treated treat VBN cord-015369-72cjogxz 5307 8 . . . cord-015369-72cjogxz 5308 1 Balloon balloon NN cord-015369-72cjogxz 5308 2 angioplasty angioplasty NN cord-015369-72cjogxz 5308 3 was be VBD cord-015369-72cjogxz 5308 4 performed perform VBN cord-015369-72cjogxz 5308 5 45 45 CD cord-015369-72cjogxz 5308 6 times time NNS cord-015369-72cjogxz 5308 7 ( ( -LRB- cord-015369-72cjogxz 5308 8 27.4 27.4 CD cord-015369-72cjogxz 5308 9 % % NN cord-015369-72cjogxz 5308 10 ) ) -RRB- cord-015369-72cjogxz 5308 11 . . . cord-015369-72cjogxz 5309 1 A a DT cord-015369-72cjogxz 5309 2 total total NN cord-015369-72cjogxz 5309 3 of of IN cord-015369-72cjogxz 5309 4 46 46 CD cord-015369-72cjogxz 5309 5 ( ( -LRB- cord-015369-72cjogxz 5309 6 28.0 28.0 CD cord-015369-72cjogxz 5309 7 % % NN cord-015369-72cjogxz 5309 8 ) ) -RRB- cord-015369-72cjogxz 5309 9 bare bare JJ cord-015369-72cjogxz 5309 10 metal metal NN cord-015369-72cjogxz 5309 11 stents stent NNS cord-015369-72cjogxz 5309 12 ( ( -LRB- cord-015369-72cjogxz 5309 13 BMS BMS NNP cord-015369-72cjogxz 5309 14 ) ) -RRB- cord-015369-72cjogxz 5309 15 and and CC cord-015369-72cjogxz 5309 16 73 73 CD cord-015369-72cjogxz 5309 17 ( ( -LRB- cord-015369-72cjogxz 5309 18 44.5 44.5 CD cord-015369-72cjogxz 5309 19 % % NN cord-015369-72cjogxz 5309 20 ) ) -RRB- cord-015369-72cjogxz 5309 21 drug drug NN cord-015369-72cjogxz 5309 22 eluting elute VBG cord-015369-72cjogxz 5309 23 stents stent NNS cord-015369-72cjogxz 5309 24 ( ( -LRB- cord-015369-72cjogxz 5309 25 DES DES NNP cord-015369-72cjogxz 5309 26 ) ) -RRB- cord-015369-72cjogxz 5309 27 were be VBD cord-015369-72cjogxz 5309 28 implanted implant VBN cord-015369-72cjogxz 5309 29 . . . cord-015369-72cjogxz 5310 1 Five five CD cord-015369-72cjogxz 5310 2 patients patient NNS cord-015369-72cjogxz 5310 3 underwent undergo VBD cord-015369-72cjogxz 5310 4 coronary coronary JJ cord-015369-72cjogxz 5310 5 bypass bypass NN cord-015369-72cjogxz 5310 6 graft graft NN cord-015369-72cjogxz 5310 7 surgery surgery NN cord-015369-72cjogxz 5310 8 . . . cord-015369-72cjogxz 5311 1 Forty forty CD cord-015369-72cjogxz 5311 2 four four CD cord-015369-72cjogxz 5311 3 percent percent NN cord-015369-72cjogxz 5311 4 of of IN cord-015369-72cjogxz 5311 5 restenosis restenosis NN cord-015369-72cjogxz 5311 6 manifested manifest VBN cord-015369-72cjogxz 5311 7 in in IN cord-015369-72cjogxz 5311 8 the the DT cord-015369-72cjogxz 5311 9 first first JJ cord-015369-72cjogxz 5311 10 6 6 CD cord-015369-72cjogxz 5311 11 months month NNS cord-015369-72cjogxz 5311 12 after after IN cord-015369-72cjogxz 5311 13 intervention intervention NN cord-015369-72cjogxz 5311 14 . . . cord-015369-72cjogxz 5312 1 Restenosis Restenosis NNP cord-015369-72cjogxz 5312 2 was be VBD cord-015369-72cjogxz 5312 3 diagnosed diagnose VBN cord-015369-72cjogxz 5312 4 during during IN cord-015369-72cjogxz 5312 5 the the DT cord-015369-72cjogxz 5312 6 long long JJ cord-015369-72cjogxz 5312 7 - - HYPH cord-015369-72cjogxz 5312 8 term term NN cord-015369-72cjogxz 5312 9 follow follow NN cord-015369-72cjogxz 5312 10 - - HYPH cord-015369-72cjogxz 5312 11 up up NN cord-015369-72cjogxz 5312 12 time time NN cord-015369-72cjogxz 5312 13 in in IN cord-015369-72cjogxz 5312 14 26.26 26.26 CD cord-015369-72cjogxz 5312 15 % % NN cord-015369-72cjogxz 5312 16 LAD lad NN cord-015369-72cjogxz 5312 17 , , , cord-015369-72cjogxz 5312 18 22.89 22.89 CD cord-015369-72cjogxz 5312 19 % % NN cord-015369-72cjogxz 5312 20 in in IN cord-015369-72cjogxz 5312 21 CX CX NNP cord-015369-72cjogxz 5312 22 and and CC cord-015369-72cjogxz 5312 23 12.99 12.99 CD cord-015369-72cjogxz 5312 24 % % NN cord-015369-72cjogxz 5312 25 in in IN cord-015369-72cjogxz 5312 26 RCA RCA NNP cord-015369-72cjogxz 5312 27 stents stent NNS cord-015369-72cjogxz 5312 28 . . . cord-015369-72cjogxz 5313 1 Within within IN cord-015369-72cjogxz 5313 2 the the DT cord-015369-72cjogxz 5313 3 first first JJ cord-015369-72cjogxz 5313 4 6 6 CD cord-015369-72cjogxz 5313 5 months month NNS cord-015369-72cjogxz 5313 6 after after IN cord-015369-72cjogxz 5313 7 intervention intervention NN cord-015369-72cjogxz 5313 8 the the DT cord-015369-72cjogxz 5313 9 mean mean JJ cord-015369-72cjogxz 5313 10 restenosis restenosis NN cord-015369-72cjogxz 5313 11 rate rate NN cord-015369-72cjogxz 5313 12 in in IN cord-015369-72cjogxz 5313 13 bare bare JJ cord-015369-72cjogxz 5313 14 metal metal NN cord-015369-72cjogxz 5313 15 stents stent NNS cord-015369-72cjogxz 5313 16 counted count VBD cord-015369-72cjogxz 5313 17 9 9 CD cord-015369-72cjogxz 5313 18 % % NN cord-015369-72cjogxz 5313 19 and and CC cord-015369-72cjogxz 5313 20 in in IN cord-015369-72cjogxz 5313 21 DES DES NNP cord-015369-72cjogxz 5313 22 7 7 CD cord-015369-72cjogxz 5313 23 % % NN cord-015369-72cjogxz 5313 24 . . . cord-015369-72cjogxz 5314 1 After after IN cord-015369-72cjogxz 5314 2 36 36 CD cord-015369-72cjogxz 5314 3 months month NNS cord-015369-72cjogxz 5314 4 72.2 72.2 CD cord-015369-72cjogxz 5314 5 % % NN cord-015369-72cjogxz 5314 6 of of IN cord-015369-72cjogxz 5314 7 stented stented JJ cord-015369-72cjogxz 5314 8 lesions lesion NNS cord-015369-72cjogxz 5314 9 remained remain VBD cord-015369-72cjogxz 5314 10 patent patent NN cord-015369-72cjogxz 5314 11 ( ( -LRB- cord-015369-72cjogxz 5314 12 63.2 63.2 CD cord-015369-72cjogxz 5314 13 % % NN cord-015369-72cjogxz 5314 14 BMS BMS NNP cord-015369-72cjogxz 5314 15 vs. vs. IN cord-015369-72cjogxz 5314 16 78.1 78.1 CD cord-015369-72cjogxz 5314 17 % % NN cord-015369-72cjogxz 5314 18 DES DES NNP cord-015369-72cjogxz 5314 19 ) ) -RRB- cord-015369-72cjogxz 5314 20 . . . cord-015369-72cjogxz 5315 1 Diabetes diabetes NN cord-015369-72cjogxz 5315 2 mellitus mellitus NN cord-015369-72cjogxz 5315 3 turned turn VBD cord-015369-72cjogxz 5315 4 out out RP cord-015369-72cjogxz 5315 5 to to TO cord-015369-72cjogxz 5315 6 be be VB cord-015369-72cjogxz 5315 7 the the DT cord-015369-72cjogxz 5315 8 only only JJ cord-015369-72cjogxz 5315 9 independent independent JJ cord-015369-72cjogxz 5315 10 predictor predictor NN cord-015369-72cjogxz 5315 11 for for IN cord-015369-72cjogxz 5315 12 early early JJ cord-015369-72cjogxz 5315 13 restenosis restenosis NN cord-015369-72cjogxz 5315 14 . . . cord-015369-72cjogxz 5316 1 The the DT cord-015369-72cjogxz 5316 2 cumulative cumulative JJ cord-015369-72cjogxz 5316 3 incidence incidence NN cord-015369-72cjogxz 5316 4 of of IN cord-015369-72cjogxz 5316 5 CAV CAV NNP cord-015369-72cjogxz 5316 6 is be VBZ cord-015369-72cjogxz 5316 7 low low JJ cord-015369-72cjogxz 5316 8 . . . cord-015369-72cjogxz 5317 1 LAD LAD NNP cord-015369-72cjogxz 5317 2 is be VBZ cord-015369-72cjogxz 5317 3 affected affect VBN cord-015369-72cjogxz 5317 4 by by IN cord-015369-72cjogxz 5317 5 the the DT cord-015369-72cjogxz 5317 6 highest high JJS cord-015369-72cjogxz 5317 7 rate rate NN cord-015369-72cjogxz 5317 8 of of IN cord-015369-72cjogxz 5317 9 restenosis restenosis NN cord-015369-72cjogxz 5317 10 . . . cord-015369-72cjogxz 5318 1 Intervention intervention NN cord-015369-72cjogxz 5318 2 of of IN cord-015369-72cjogxz 5318 3 focal focal JJ cord-015369-72cjogxz 5318 4 lesions lesion NNS cord-015369-72cjogxz 5318 5 in in IN cord-015369-72cjogxz 5318 6 CAV CAV NNP cord-015369-72cjogxz 5318 7 patients patient NNS cord-015369-72cjogxz 5318 8 is be VBZ cord-015369-72cjogxz 5318 9 feasible feasible JJ cord-015369-72cjogxz 5318 10 and and CC cord-015369-72cjogxz 5318 11 effective effective JJ cord-015369-72cjogxz 5318 12 as as IN cord-015369-72cjogxz 5318 13 it -PRON- PRP cord-015369-72cjogxz 5318 14 is be VBZ cord-015369-72cjogxz 5318 15 in in IN cord-015369-72cjogxz 5318 16 non non JJ cord-015369-72cjogxz 5318 17 - - JJ cord-015369-72cjogxz 5318 18 transplant transplant JJ cord-015369-72cjogxz 5318 19 coronary coronary JJ cord-015369-72cjogxz 5318 20 artery artery NN cord-015369-72cjogxz 5318 21 disease disease NN cord-015369-72cjogxz 5318 22 . . . cord-015369-72cjogxz 5319 1 A a DT cord-015369-72cjogxz 5319 2 trend trend NN cord-015369-72cjogxz 5319 3 towards towards IN cord-015369-72cjogxz 5319 4 improved improved JJ cord-015369-72cjogxz 5319 5 patency patency NN cord-015369-72cjogxz 5319 6 with with IN cord-015369-72cjogxz 5319 7 DES DES NNP cord-015369-72cjogxz 5319 8 could could MD cord-015369-72cjogxz 5319 9 be be VB cord-015369-72cjogxz 5319 10 observed observe VBN cord-015369-72cjogxz 5319 11 . . . cord-015369-72cjogxz 5320 1 Background background NN cord-015369-72cjogxz 5320 2 . . . cord-015369-72cjogxz 5321 1 This this DT cord-015369-72cjogxz 5321 2 study study NN cord-015369-72cjogxz 5321 3 was be VBD cord-015369-72cjogxz 5321 4 designed design VBN cord-015369-72cjogxz 5321 5 to to TO cord-015369-72cjogxz 5321 6 determine determine VB cord-015369-72cjogxz 5321 7 the the DT cord-015369-72cjogxz 5321 8 posttransplant posttransplant NN cord-015369-72cjogxz 5321 9 outcome outcome NN cord-015369-72cjogxz 5321 10 of of IN cord-015369-72cjogxz 5321 11 elective elective JJ cord-015369-72cjogxz 5321 12 , , , cord-015369-72cjogxz 5321 13 LVAD LVAD NNP cord-015369-72cjogxz 5321 14 and and CC cord-015369-72cjogxz 5321 15 urgent urgent JJ cord-015369-72cjogxz 5321 16 patients patient NNS cord-015369-72cjogxz 5321 17 undergoing undergo VBG cord-015369-72cjogxz 5321 18 cardiac cardiac JJ cord-015369-72cjogxz 5321 19 transplantation transplantation NN cord-015369-72cjogxz 5321 20 . . . cord-015369-72cjogxz 5322 1 Methods method NNS cord-015369-72cjogxz 5322 2 . . . cord-015369-72cjogxz 5323 1 The the DT cord-015369-72cjogxz 5323 2 post post JJ cord-015369-72cjogxz 5323 3 - - JJ cord-015369-72cjogxz 5323 4 transplant transplant JJ cord-015369-72cjogxz 5323 5 outcome outcome NN cord-015369-72cjogxz 5323 6 of of IN cord-015369-72cjogxz 5323 7 485 485 CD cord-015369-72cjogxz 5323 8 elective elective NN cord-015369-72cjogxz 5323 9 , , , cord-015369-72cjogxz 5323 10 64 64 CD cord-015369-72cjogxz 5323 11 LVAD LVAD NNP cord-015369-72cjogxz 5323 12 ( ( -LRB- cord-015369-72cjogxz 5323 13 DeBakey DeBakey NNP cord-015369-72cjogxz 5323 14 , , , cord-015369-72cjogxz 5323 15 Duraheart Duraheart NNP cord-015369-72cjogxz 5323 16 , , , cord-015369-72cjogxz 5323 17 Heartware Heartware NNP cord-015369-72cjogxz 5323 18 LVAD LVAD NNP cord-015369-72cjogxz 5323 19 ) ) -RRB- cord-015369-72cjogxz 5323 20 and and CC cord-015369-72cjogxz 5323 21 43 43 CD cord-015369-72cjogxz 5323 22 urgent urgent JJ cord-015369-72cjogxz 5323 23 patients patient NNS cord-015369-72cjogxz 5323 24 ( ( -LRB- cord-015369-72cjogxz 5323 25 HU HU NNP cord-015369-72cjogxz 5323 26 ) ) -RRB- cord-015369-72cjogxz 5323 27 undergoing undergo VBG cord-015369-72cjogxz 5323 28 cardiac cardiac JJ cord-015369-72cjogxz 5323 29 transplantation transplantation NN cord-015369-72cjogxz 5323 30 between between IN cord-015369-72cjogxz 5323 31 1998 1998 CD cord-015369-72cjogxz 5323 32 and and CC cord-015369-72cjogxz 5323 33 2008 2008 CD cord-015369-72cjogxz 5323 34 was be VBD cord-015369-72cjogxz 5323 35 retrospectively retrospectively RB cord-015369-72cjogxz 5323 36 analyzed analyze VBN cord-015369-72cjogxz 5323 37 . . . cord-015369-72cjogxz 5324 1 Survival survival NN cord-015369-72cjogxz 5324 2 , , , cord-015369-72cjogxz 5324 3 incidence incidence NN cord-015369-72cjogxz 5324 4 of of IN cord-015369-72cjogxz 5324 5 rejection rejection NN cord-015369-72cjogxz 5324 6 , , , cord-015369-72cjogxz 5324 7 severe severe JJ cord-015369-72cjogxz 5324 8 infections infection NNS cord-015369-72cjogxz 5324 9 , , , cord-015369-72cjogxz 5324 10 CMV cmv NN cord-015369-72cjogxz 5324 11 - - HYPH cord-015369-72cjogxz 5324 12 disease disease NN cord-015369-72cjogxz 5324 13 and and CC cord-015369-72cjogxz 5324 14 graft graft NN cord-015369-72cjogxz 5324 15 vasculopathy vasculopathy NNP cord-015369-72cjogxz 5324 16 ( ( -LRB- cord-015369-72cjogxz 5324 17 CAV CAV NNP cord-015369-72cjogxz 5324 18 ) ) -RRB- cord-015369-72cjogxz 5324 19 were be VBD cord-015369-72cjogxz 5324 20 compared compare VBN cord-015369-72cjogxz 5324 21 . . . cord-015369-72cjogxz 5325 1 All all DT cord-015369-72cjogxz 5325 2 patients patient NNS cord-015369-72cjogxz 5325 3 received receive VBD cord-015369-72cjogxz 5325 4 immunosuppressive immunosuppressive JJ cord-015369-72cjogxz 5325 5 therapy therapy NN cord-015369-72cjogxz 5325 6 consisting consist VBG cord-015369-72cjogxz 5325 7 of of IN cord-015369-72cjogxz 5325 8 thymoglobuline thymoglobuline NN cord-015369-72cjogxz 5325 9 , , , cord-015369-72cjogxz 5325 10 Tac Tac NNP cord-015369-72cjogxz 5325 11 / / SYM cord-015369-72cjogxz 5325 12 Cyclo Cyclo NNP cord-015369-72cjogxz 5325 13 þ þ NNP cord-015369-72cjogxz 5325 14 MMF mmf NN cord-015369-72cjogxz 5325 15 / / SYM cord-015369-72cjogxz 5325 16 Evl Evl NNP cord-015369-72cjogxz 5325 17 and and CC cord-015369-72cjogxz 5325 18 low low JJ cord-015369-72cjogxz 5325 19 dose dose NN cord-015369-72cjogxz 5325 20 steroids steroid NNS cord-015369-72cjogxz 5325 21 . . . cord-015369-72cjogxz 5326 1 Kaplan Kaplan NNP cord-015369-72cjogxz 5326 2 - - HYPH cord-015369-72cjogxz 5326 3 Meier Meier NNP cord-015369-72cjogxz 5326 4 analysis analysis NN cord-015369-72cjogxz 5326 5 was be VBD cord-015369-72cjogxz 5326 6 performed perform VBN cord-015369-72cjogxz 5326 7 to to TO cord-015369-72cjogxz 5326 8 test test VB cord-015369-72cjogxz 5326 9 differences difference NNS cord-015369-72cjogxz 5326 10 between between IN cord-015369-72cjogxz 5326 11 the the DT cord-015369-72cjogxz 5326 12 groups group NNS cord-015369-72cjogxz 5326 13 . . . cord-015369-72cjogxz 5327 1 Results result NNS cord-015369-72cjogxz 5327 2 . . . cord-015369-72cjogxz 5328 1 Patients patient NNS cord-015369-72cjogxz 5328 2 in in IN cord-015369-72cjogxz 5328 3 the the DT cord-015369-72cjogxz 5328 4 three three CD cord-015369-72cjogxz 5328 5 groups group NNS cord-015369-72cjogxz 5328 6 were be VBD cord-015369-72cjogxz 5328 7 comparable comparable JJ cord-015369-72cjogxz 5328 8 with with IN cord-015369-72cjogxz 5328 9 regard regard NN cord-015369-72cjogxz 5328 10 to to IN cord-015369-72cjogxz 5328 11 primary primary JJ cord-015369-72cjogxz 5328 12 disease disease NN cord-015369-72cjogxz 5328 13 . . . cord-015369-72cjogxz 5329 1 Urgent urgent JJ cord-015369-72cjogxz 5329 2 patients patient NNS cord-015369-72cjogxz 5329 3 were be VBD cord-015369-72cjogxz 5329 4 younger young JJR cord-015369-72cjogxz 5329 5 ( ( -LRB- cord-015369-72cjogxz 5329 6 42 42 CD cord-015369-72cjogxz 5329 7 AE AE NNP cord-015369-72cjogxz 5329 8 16yrs 16yrs NNP cord-015369-72cjogxz 5329 9 ) ) -RRB- cord-015369-72cjogxz 5329 10 than than IN cord-015369-72cjogxz 5329 11 elective elective JJ cord-015369-72cjogxz 5329 12 ( ( -LRB- cord-015369-72cjogxz 5329 13 52 52 CD cord-015369-72cjogxz 5329 14 AE AE NNP cord-015369-72cjogxz 5329 15 13yrs 13yrs NNP cord-015369-72cjogxz 5329 16 ) ) -RRB- cord-015369-72cjogxz 5329 17 and and CC cord-015369-72cjogxz 5329 18 LVAD LVAD NNP cord-015369-72cjogxz 5329 19 ( ( -LRB- cord-015369-72cjogxz 5329 20 50 50 CD cord-015369-72cjogxz 5329 21 AE AE NNP cord-015369-72cjogxz 5329 22 11yrs 11yrs NNP cord-015369-72cjogxz 5329 23 ) ) -RRB- cord-015369-72cjogxz 5329 24 patients patient NNS cord-015369-72cjogxz 5329 25 ( ( -LRB- cord-015369-72cjogxz 5329 26 p p NN cord-015369-72cjogxz 5329 27 < < XX cord-015369-72cjogxz 5329 28 0.001 0.001 CD cord-015369-72cjogxz 5329 29 ) ) -RRB- cord-015369-72cjogxz 5329 30 . . . cord-015369-72cjogxz 5330 1 Actuarial actuarial JJ cord-015369-72cjogxz 5330 2 survival survival NN cord-015369-72cjogxz 5330 3 of of IN cord-015369-72cjogxz 5330 4 elective elective JJ cord-015369-72cjogxz 5330 5 ( ( -LRB- cord-015369-72cjogxz 5330 6 80 80 CD cord-015369-72cjogxz 5330 7 % % NN cord-015369-72cjogxz 5330 8 , , , cord-015369-72cjogxz 5330 9 75 75 CD cord-015369-72cjogxz 5330 10 % % NN cord-015369-72cjogxz 5330 11 , , , cord-015369-72cjogxz 5330 12 72 72 CD cord-015369-72cjogxz 5330 13 % % NN cord-015369-72cjogxz 5330 14 ) ) -RRB- cord-015369-72cjogxz 5330 15 , , , cord-015369-72cjogxz 5330 16 LVAD LVAD NNP cord-015369-72cjogxz 5330 17 ( ( -LRB- cord-015369-72cjogxz 5330 18 84 84 CD cord-015369-72cjogxz 5330 19 % % NN cord-015369-72cjogxz 5330 20 , , , cord-015369-72cjogxz 5330 21 77 77 CD cord-015369-72cjogxz 5330 22 % % NN cord-015369-72cjogxz 5330 23 , , , cord-015369-72cjogxz 5330 24 71 71 CD cord-015369-72cjogxz 5330 25 % % NN cord-015369-72cjogxz 5330 26 ) ) -RRB- cord-015369-72cjogxz 5330 27 and and CC cord-015369-72cjogxz 5330 28 HU HU NNP cord-015369-72cjogxz 5330 29 ( ( -LRB- cord-015369-72cjogxz 5330 30 81 81 CD cord-015369-72cjogxz 5330 31 % % NN cord-015369-72cjogxz 5330 32 , , , cord-015369-72cjogxz 5330 33 78 78 CD cord-015369-72cjogxz 5330 34 % % NN cord-015369-72cjogxz 5330 35 , , , cord-015369-72cjogxz 5330 36 71 71 CD cord-015369-72cjogxz 5330 37 % % NN cord-015369-72cjogxz 5330 38 ) ) -RRB- cord-015369-72cjogxz 5330 39 patients patient NNS cord-015369-72cjogxz 5330 40 was be VBD cord-015369-72cjogxz 5330 41 comparable comparable JJ cord-015369-72cjogxz 5330 42 1 1 CD cord-015369-72cjogxz 5330 43 , , , cord-015369-72cjogxz 5330 44 3 3 CD cord-015369-72cjogxz 5330 45 and and CC cord-015369-72cjogxz 5330 46 5 5 CD cord-015369-72cjogxz 5330 47 years year NNS cord-015369-72cjogxz 5330 48 post post JJ cord-015369-72cjogxz 5330 49 - - NN cord-015369-72cjogxz 5330 50 transplant transplant JJ cord-015369-72cjogxz 5330 51 ( ( -LRB- cord-015369-72cjogxz 5330 52 log log NN cord-015369-72cjogxz 5330 53 - - HYPH cord-015369-72cjogxz 5330 54 rank rank NN cord-015369-72cjogxz 5330 55 0.671 0.671 CD cord-015369-72cjogxz 5330 56 ) ) -RRB- cord-015369-72cjogxz 5330 57 . . . cord-015369-72cjogxz 5331 1 Furthermore furthermore RB cord-015369-72cjogxz 5331 2 , , , cord-015369-72cjogxz 5331 3 freedom freedom NN cord-015369-72cjogxz 5331 4 from from IN cord-015369-72cjogxz 5331 5 rejection rejection NN cord-015369-72cjogxz 5331 6 episodes episode NNS cord-015369-72cjogxz 5331 7 ( ( -LRB- cord-015369-72cjogxz 5331 8 elective elective JJ cord-015369-72cjogxz 5331 9 : : : cord-015369-72cjogxz 5331 10 91 91 CD cord-015369-72cjogxz 5331 11 % % NN cord-015369-72cjogxz 5331 12 , , , cord-015369-72cjogxz 5331 13 90 90 CD cord-015369-72cjogxz 5331 14 % % NN cord-015369-72cjogxz 5331 15 , , , cord-015369-72cjogxz 5331 16 90 90 CD cord-015369-72cjogxz 5331 17 % % NN cord-015369-72cjogxz 5331 18 , , , cord-015369-72cjogxz 5331 19 LVAD LVAD NNP cord-015369-72cjogxz 5331 20 : : : cord-015369-72cjogxz 5331 21 90 90 CD cord-015369-72cjogxz 5331 22 % % NN cord-015369-72cjogxz 5331 23 , , , cord-015369-72cjogxz 5331 24 90 90 CD cord-015369-72cjogxz 5331 25 % % NN cord-015369-72cjogxz 5331 26 , , , cord-015369-72cjogxz 5331 27 90 90 CD cord-015369-72cjogxz 5331 28 % % NN cord-015369-72cjogxz 5331 29 , , , cord-015369-72cjogxz 5331 30 HU HU NNP cord-015369-72cjogxz 5331 31 : : : cord-015369-72cjogxz 5331 32 93 93 CD cord-015369-72cjogxz 5331 33 % % NN cord-015369-72cjogxz 5331 34 , , , cord-015369-72cjogxz 5331 35 93 93 CD cord-015369-72cjogxz 5331 36 % % NN cord-015369-72cjogxz 5331 37 , , , cord-015369-72cjogxz 5331 38 93 93 CD cord-015369-72cjogxz 5331 39 % % NN cord-015369-72cjogxz 5331 40 ; ; : cord-015369-72cjogxz 5331 41 log log NN cord-015369-72cjogxz 5331 42 - - HYPH cord-015369-72cjogxz 5331 43 rank rank NN cord-015369-72cjogxz 5331 44 0.991 0.991 CD cord-015369-72cjogxz 5331 45 ) ) -RRB- cord-015369-72cjogxz 5331 46 , , , cord-015369-72cjogxz 5331 47 severe severe JJ cord-015369-72cjogxz 5331 48 infections infection NNS cord-015369-72cjogxz 5331 49 ( ( -LRB- cord-015369-72cjogxz 5331 50 elective elective JJ cord-015369-72cjogxz 5331 51 : : : cord-015369-72cjogxz 5331 52 73 73 CD cord-015369-72cjogxz 5331 53 % % NN cord-015369-72cjogxz 5331 54 , , , cord-015369-72cjogxz 5331 55 68 68 CD cord-015369-72cjogxz 5331 56 % % NN cord-015369-72cjogxz 5331 57 , , , cord-015369-72cjogxz 5331 58 67 67 CD cord-015369-72cjogxz 5331 59 % % NN cord-015369-72cjogxz 5331 60 , , , cord-015369-72cjogxz 5331 61 LVAD LVAD NNP cord-015369-72cjogxz 5331 62 : : : cord-015369-72cjogxz 5331 63 84 84 CD cord-015369-72cjogxz 5331 64 % % NN cord-015369-72cjogxz 5331 65 , , , cord-015369-72cjogxz 5331 66 82 82 CD cord-015369-72cjogxz 5331 67 % % NN cord-015369-72cjogxz 5331 68 , , , cord-015369-72cjogxz 5331 69 82 82 CD cord-015369-72cjogxz 5331 70 , , , cord-015369-72cjogxz 5331 71 HU HU NNP cord-015369-72cjogxz 5331 72 : : : cord-015369-72cjogxz 5331 73 73 73 CD cord-015369-72cjogxz 5331 74 % % NN cord-015369-72cjogxz 5331 75 , , , cord-015369-72cjogxz 5331 76 73 73 CD cord-015369-72cjogxz 5331 77 % % NN cord-015369-72cjogxz 5331 78 , , , cord-015369-72cjogxz 5331 79 70 70 CD cord-015369-72cjogxz 5331 80 % % NN cord-015369-72cjogxz 5331 81 ; ; : cord-015369-72cjogxz 5331 82 log log NN cord-015369-72cjogxz 5331 83 - - HYPH cord-015369-72cjogxz 5331 84 rank rank NN cord-015369-72cjogxz 5331 85 0.118 0.118 CD cord-015369-72cjogxz 5331 86 ) ) -RRB- cord-015369-72cjogxz 5331 87 , , , cord-015369-72cjogxz 5331 88 CMV CMV NNP cord-015369-72cjogxz 5331 89 disease disease NN cord-015369-72cjogxz 5331 90 ( ( -LRB- cord-015369-72cjogxz 5331 91 elective elective JJ cord-015369-72cjogxz 5331 92 : : : cord-015369-72cjogxz 5331 93 91 91 CD cord-015369-72cjogxz 5331 94 % % NN cord-015369-72cjogxz 5331 95 , , , cord-015369-72cjogxz 5331 96 90 90 CD cord-015369-72cjogxz 5331 97 % % NN cord-015369-72cjogxz 5331 98 , , , cord-015369-72cjogxz 5331 99 90 90 CD cord-015369-72cjogxz 5331 100 % % NN cord-015369-72cjogxz 5331 101 , , , cord-015369-72cjogxz 5331 102 LVAD:92 LVAD:92 NNP cord-015369-72cjogxz 5331 103 % % NN cord-015369-72cjogxz 5331 104 , , , cord-015369-72cjogxz 5331 105 92 92 CD cord-015369-72cjogxz 5331 106 % % NN cord-015369-72cjogxz 5331 107 , , , cord-015369-72cjogxz 5331 108 92 92 CD cord-015369-72cjogxz 5331 109 % % NN cord-015369-72cjogxz 5331 110 , , , cord-015369-72cjogxz 5331 111 HU HU NNP cord-015369-72cjogxz 5331 112 : : : cord-015369-72cjogxz 5331 113 86 86 CD cord-015369-72cjogxz 5331 114 % % NN cord-015369-72cjogxz 5331 115 , , , cord-015369-72cjogxz 5331 116 86 86 CD cord-015369-72cjogxz 5331 117 % % NN cord-015369-72cjogxz 5331 118 , , , cord-015369-72cjogxz 5331 119 86 86 CD cord-015369-72cjogxz 5331 120 % % NN cord-015369-72cjogxz 5331 121 ; ; : cord-015369-72cjogxz 5331 122 log log NN cord-015369-72cjogxz 5331 123 - - HYPH cord-015369-72cjogxz 5331 124 rank rank NN cord-015369-72cjogxz 5331 125 0.415 0.415 CD cord-015369-72cjogxz 5331 126 ) ) -RRB- cord-015369-72cjogxz 5331 127 and and CC cord-015369-72cjogxz 5331 128 CAV CAV NNP cord-015369-72cjogxz 5331 129 ( ( -LRB- cord-015369-72cjogxz 5331 130 elective elective NNP cord-015369-72cjogxz 5331 131 : : : cord-015369-72cjogxz 5331 132 97 97 CD cord-015369-72cjogxz 5331 133 % % NN cord-015369-72cjogxz 5331 134 , , , cord-015369-72cjogxz 5331 135 92 92 CD cord-015369-72cjogxz 5331 136 % % NN cord-015369-72cjogxz 5331 137 , , , cord-015369-72cjogxz 5331 138 85 85 CD cord-015369-72cjogxz 5331 139 % % NN cord-015369-72cjogxz 5331 140 , , , cord-015369-72cjogxz 5331 141 LVAD LVAD NNP cord-015369-72cjogxz 5331 142 : : : cord-015369-72cjogxz 5331 143 96 96 CD cord-015369-72cjogxz 5331 144 % % NN cord-015369-72cjogxz 5331 145 , , , cord-015369-72cjogxz 5331 146 89 89 CD cord-015369-72cjogxz 5331 147 % % NN cord-015369-72cjogxz 5331 148 , , , cord-015369-72cjogxz 5331 149 83 83 CD cord-015369-72cjogxz 5331 150 % % NN cord-015369-72cjogxz 5331 151 , , , cord-015369-72cjogxz 5331 152 HU HU NNP cord-015369-72cjogxz 5331 153 : : : cord-015369-72cjogxz 5331 154 94 94 CD cord-015369-72cjogxz 5331 155 % % NN cord-015369-72cjogxz 5331 156 , , , cord-015369-72cjogxz 5331 157 82 82 CD cord-015369-72cjogxz 5331 158 % % NN cord-015369-72cjogxz 5331 159 , , , cord-015369-72cjogxz 5331 160 82 82 CD cord-015369-72cjogxz 5331 161 % % NN cord-015369-72cjogxz 5331 162 ; ; : cord-015369-72cjogxz 5331 163 log log NN cord-015369-72cjogxz 5331 164 - - HYPH cord-015369-72cjogxz 5331 165 rank rank NN cord-015369-72cjogxz 5331 166 0.317 0.317 CD cord-015369-72cjogxz 5331 167 ) ) -RRB- cord-015369-72cjogxz 5331 168 was be VBD cord-015369-72cjogxz 5331 169 comparable comparable JJ cord-015369-72cjogxz 5331 170 between between IN cord-015369-72cjogxz 5331 171 elective elective NN cord-015369-72cjogxz 5331 172 , , , cord-015369-72cjogxz 5331 173 LVAD LVAD NNP cord-015369-72cjogxz 5331 174 and and CC cord-015369-72cjogxz 5331 175 HU HU NNP cord-015369-72cjogxz 5331 176 patients patient NNS cord-015369-72cjogxz 5331 177 1 1 CD cord-015369-72cjogxz 5331 178 , , , cord-015369-72cjogxz 5331 179 3 3 CD cord-015369-72cjogxz 5331 180 , , , cord-015369-72cjogxz 5331 181 and and CC cord-015369-72cjogxz 5331 182 5 5 CD cord-015369-72cjogxz 5331 183 years year NNS cord-015369-72cjogxz 5331 184 posttransplant posttransplant JJ cord-015369-72cjogxz 5331 185 . . . cord-015369-72cjogxz 5332 1 Conclusions conclusion NNS cord-015369-72cjogxz 5332 2 . . . cord-015369-72cjogxz 5333 1 Despite despite IN cord-015369-72cjogxz 5333 2 the the DT cord-015369-72cjogxz 5333 3 increased increase VBN cord-015369-72cjogxz 5333 4 risk risk NN cord-015369-72cjogxz 5333 5 of of IN cord-015369-72cjogxz 5333 6 LVAD LVAD NNP cord-015369-72cjogxz 5333 7 and and CC cord-015369-72cjogxz 5333 8 urgent urgent JJ cord-015369-72cjogxz 5333 9 patients patient NNS cord-015369-72cjogxz 5333 10 post post JJ cord-015369-72cjogxz 5333 11 - - JJ cord-015369-72cjogxz 5333 12 transplant transplant JJ cord-015369-72cjogxz 5333 13 outcome outcome NN cord-015369-72cjogxz 5333 14 is be VBZ cord-015369-72cjogxz 5333 15 excellent excellent JJ cord-015369-72cjogxz 5333 16 and and CC cord-015369-72cjogxz 5333 17 compares compare VBZ cord-015369-72cjogxz 5333 18 to to IN cord-015369-72cjogxz 5333 19 elective elective JJ cord-015369-72cjogxz 5333 20 patients patient NNS cord-015369-72cjogxz 5333 21 . . . cord-015369-72cjogxz 5334 1 The the DT cord-015369-72cjogxz 5334 2 low low JJ cord-015369-72cjogxz 5334 3 incidence incidence NN cord-015369-72cjogxz 5334 4 of of IN cord-015369-72cjogxz 5334 5 rejections rejection NNS cord-015369-72cjogxz 5334 6 and and CC cord-015369-72cjogxz 5334 7 CAV CAV NNP cord-015369-72cjogxz 5334 8 underlines underline VBZ cord-015369-72cjogxz 5334 9 the the DT cord-015369-72cjogxz 5334 10 importance importance NN cord-015369-72cjogxz 5334 11 of of IN cord-015369-72cjogxz 5334 12 induction induction NN cord-015369-72cjogxz 5334 13 therapy therapy NN cord-015369-72cjogxz 5334 14 and and CC cord-015369-72cjogxz 5334 15 individualized individualized JJ cord-015369-72cjogxz 5334 16 immunosuppression immunosuppression NN cord-015369-72cjogxz 5334 17 . . . cord-015369-72cjogxz 5335 1 Background background NN cord-015369-72cjogxz 5335 2 . . . cord-015369-72cjogxz 5336 1 PGD PGD NNP cord-015369-72cjogxz 5336 2 is be VBZ cord-015369-72cjogxz 5336 3 a a DT cord-015369-72cjogxz 5336 4 major major JJ cord-015369-72cjogxz 5336 5 cause cause NN cord-015369-72cjogxz 5336 6 of of IN cord-015369-72cjogxz 5336 7 morbidity morbidity NN cord-015369-72cjogxz 5336 8 and and CC cord-015369-72cjogxz 5336 9 death death NN cord-015369-72cjogxz 5336 10 early early RB cord-015369-72cjogxz 5336 11 after after IN cord-015369-72cjogxz 5336 12 cardiac cardiac JJ cord-015369-72cjogxz 5336 13 transplantation transplantation NN cord-015369-72cjogxz 5336 14 . . . cord-015369-72cjogxz 5337 1 Extracorporeal extracorporeal JJ cord-015369-72cjogxz 5337 2 membrane membrane NN cord-015369-72cjogxz 5337 3 oxygenation oxygenation NN cord-015369-72cjogxz 5337 4 ( ( -LRB- cord-015369-72cjogxz 5337 5 ECMO ECMO NNP cord-015369-72cjogxz 5337 6 ) ) -RRB- cord-015369-72cjogxz 5337 7 is be VBZ cord-015369-72cjogxz 5337 8 a a DT cord-015369-72cjogxz 5337 9 mechanical mechanical JJ cord-015369-72cjogxz 5337 10 support support NN cord-015369-72cjogxz 5337 11 system system NN cord-015369-72cjogxz 5337 12 to to TO cord-015369-72cjogxz 5337 13 support support VB cord-015369-72cjogxz 5337 14 hemodynamics hemodynamic NNS cord-015369-72cjogxz 5337 15 in in IN cord-015369-72cjogxz 5337 16 case case NN cord-015369-72cjogxz 5337 17 of of IN cord-015369-72cjogxz 5337 18 acute acute JJ cord-015369-72cjogxz 5337 19 heart heart NN cord-015369-72cjogxz 5337 20 failure failure NN cord-015369-72cjogxz 5337 21 . . . cord-015369-72cjogxz 5338 1 The the DT cord-015369-72cjogxz 5338 2 aim aim NN cord-015369-72cjogxz 5338 3 of of IN cord-015369-72cjogxz 5338 4 this this DT cord-015369-72cjogxz 5338 5 study study NN cord-015369-72cjogxz 5338 6 was be VBD cord-015369-72cjogxz 5338 7 to to TO cord-015369-72cjogxz 5338 8 evaluate evaluate VB cord-015369-72cjogxz 5338 9 ECMO ECMO NNP cord-015369-72cjogxz 5338 10 as as IN cord-015369-72cjogxz 5338 11 support support NN cord-015369-72cjogxz 5338 12 system system NN cord-015369-72cjogxz 5338 13 for for IN cord-015369-72cjogxz 5338 14 PGD PGD NNP cord-015369-72cjogxz 5338 15 . . . cord-015369-72cjogxz 5339 1 Methods method NNS cord-015369-72cjogxz 5339 2 . . . cord-015369-72cjogxz 5340 1 Between between IN cord-015369-72cjogxz 5340 2 2000 2000 CD cord-015369-72cjogxz 5340 3 and and CC cord-015369-72cjogxz 5340 4 2008 2008 CD cord-015369-72cjogxz 5340 5 59 59 CD cord-015369-72cjogxz 5340 6 out out IN cord-015369-72cjogxz 5340 7 of of IN cord-015369-72cjogxz 5340 8 425 425 CD cord-015369-72cjogxz 5340 9 ( ( -LRB- cord-015369-72cjogxz 5340 10 14 14 CD cord-015369-72cjogxz 5340 11 % % NN cord-015369-72cjogxz 5340 12 ) ) -RRB- cord-015369-72cjogxz 5340 13 patients patient NNS cord-015369-72cjogxz 5340 14 , , , cord-015369-72cjogxz 5340 15 who who WP cord-015369-72cjogxz 5340 16 underwent undergo VBD cord-015369-72cjogxz 5340 17 cardiac cardiac JJ cord-015369-72cjogxz 5340 18 transplantation transplantation NN cord-015369-72cjogxz 5340 19 , , , cord-015369-72cjogxz 5340 20 experienced experience VBD cord-015369-72cjogxz 5340 21 PGD PGD NNP cord-015369-72cjogxz 5340 22 and and CC cord-015369-72cjogxz 5340 23 received receive VBD cord-015369-72cjogxz 5340 24 ECMO ECMO NNP cord-015369-72cjogxz 5340 25 support support NN cord-015369-72cjogxz 5340 26 . . . cord-015369-72cjogxz 5341 1 Survival survival NN cord-015369-72cjogxz 5341 2 , , , cord-015369-72cjogxz 5341 3 rate rate NN cord-015369-72cjogxz 5341 4 of of IN cord-015369-72cjogxz 5341 5 recovery recovery NN cord-015369-72cjogxz 5341 6 and and CC cord-015369-72cjogxz 5341 7 complications complication NNS cord-015369-72cjogxz 5341 8 were be VBD cord-015369-72cjogxz 5341 9 analysed analyse VBN cord-015369-72cjogxz 5341 10 . . . cord-015369-72cjogxz 5342 1 Results result NNS cord-015369-72cjogxz 5342 2 . . . cord-015369-72cjogxz 5343 1 Overall overall JJ cord-015369-72cjogxz 5343 2 survival survival NN cord-015369-72cjogxz 5343 3 was be VBD cord-015369-72cjogxz 5343 4 41 41 CD cord-015369-72cjogxz 5343 5 % % NN cord-015369-72cjogxz 5343 6 after after IN cord-015369-72cjogxz 5343 7 100 100 CD cord-015369-72cjogxz 5343 8 weeks week NNS cord-015369-72cjogxz 5343 9 follow follow VBP cord-015369-72cjogxz 5343 10 up up RP cord-015369-72cjogxz 5343 11 . . . cord-015369-72cjogxz 5344 1 44 44 CD cord-015369-72cjogxz 5344 2 patients patient NNS cord-015369-72cjogxz 5344 3 ( ( -LRB- cord-015369-72cjogxz 5344 4 74.6 74.6 CD cord-015369-72cjogxz 5344 5 % % NN cord-015369-72cjogxz 5344 6 ) ) -RRB- cord-015369-72cjogxz 5344 7 could could MD cord-015369-72cjogxz 5344 8 be be VB cord-015369-72cjogxz 5344 9 weaned wean VBN cord-015369-72cjogxz 5344 10 from from IN cord-015369-72cjogxz 5344 11 ECMO ECMO NNP cord-015369-72cjogxz 5344 12 and and CC cord-015369-72cjogxz 5344 13 in in IN cord-015369-72cjogxz 5344 14 - - HYPH cord-015369-72cjogxz 5344 15 hospital hospital NN cord-015369-72cjogxz 5344 16 survival survival NN cord-015369-72cjogxz 5344 17 of of IN cord-015369-72cjogxz 5344 18 these these DT cord-015369-72cjogxz 5344 19 patients patient NNS cord-015369-72cjogxz 5344 20 was be VBD cord-015369-72cjogxz 5344 21 55 55 CD cord-015369-72cjogxz 5344 22 % % NN cord-015369-72cjogxz 5344 23 . . . cord-015369-72cjogxz 5345 1 Duration duration NN cord-015369-72cjogxz 5345 2 of of IN cord-015369-72cjogxz 5345 3 ECMO ECMO NNP cord-015369-72cjogxz 5345 4 support support NN cord-015369-72cjogxz 5345 5 was be VBD cord-015369-72cjogxz 5345 6 4 4 CD cord-015369-72cjogxz 5345 7 days day NNS cord-015369-72cjogxz 5345 8 . . . cord-015369-72cjogxz 5346 1 Early early JJ cord-015369-72cjogxz 5346 2 experience experience NN cord-015369-72cjogxz 5346 3 ( ( -LRB- cord-015369-72cjogxz 5346 4 2000 2000 CD cord-015369-72cjogxz 5346 5 ) ) -RRB- cord-015369-72cjogxz 5346 6 ( ( -LRB- cord-015369-72cjogxz 5346 7 2001 2001 CD cord-015369-72cjogxz 5346 8 ) ) -RRB- cord-015369-72cjogxz 5346 9 ( ( -LRB- cord-015369-72cjogxz 5346 10 2002 2002 CD cord-015369-72cjogxz 5346 11 ) ) -RRB- cord-015369-72cjogxz 5346 12 ( ( -LRB- cord-015369-72cjogxz 5346 13 2003 2003 CD cord-015369-72cjogxz 5346 14 ) ) -RRB- cord-015369-72cjogxz 5346 15 with with IN cord-015369-72cjogxz 5346 16 ECMO ECMO NNP cord-015369-72cjogxz 5346 17 was be VBD cord-015369-72cjogxz 5346 18 significantly significantly RB cord-015369-72cjogxz 5346 19 worse bad JJR cord-015369-72cjogxz 5346 20 ( ( -LRB- cord-015369-72cjogxz 5346 21 survival survival NN cord-015369-72cjogxz 5346 22 : : : cord-015369-72cjogxz 5346 23 20 20 CD cord-015369-72cjogxz 5346 24 % % NN cord-015369-72cjogxz 5346 25 vs. vs. CC cord-015369-72cjogxz 5346 26 50 50 CD cord-015369-72cjogxz 5346 27 % % NN cord-015369-72cjogxz 5346 28 ; ; : cord-015369-72cjogxz 5346 29 p p NN cord-015369-72cjogxz 5346 30 ¼ ¼ CD cord-015369-72cjogxz 5346 31 0.001 0.001 CD cord-015369-72cjogxz 5346 32 ) ) -RRB- cord-015369-72cjogxz 5346 33 than than IN cord-015369-72cjogxz 5346 34 later later JJ cord-015369-72cjogxz 5346 35 experience experience NN cord-015369-72cjogxz 5346 36 ( ( -LRB- cord-015369-72cjogxz 5346 37 2004 2004 CD cord-015369-72cjogxz 5346 38 - - SYM cord-015369-72cjogxz 5346 39 08 08 CD cord-015369-72cjogxz 5346 40 ) ) -RRB- cord-015369-72cjogxz 5346 41 . . . cord-015369-72cjogxz 5347 1 Overall overall JJ cord-015369-72cjogxz 5347 2 complication complication NN cord-015369-72cjogxz 5347 3 rate rate NN cord-015369-72cjogxz 5347 4 was be VBD cord-015369-72cjogxz 5347 5 68 68 CD cord-015369-72cjogxz 5347 6 % % NN cord-015369-72cjogxz 5347 7 . . . cord-015369-72cjogxz 5348 1 Most Most JJS cord-015369-72cjogxz 5348 2 frequent frequent JJ cord-015369-72cjogxz 5348 3 complications complication NNS cord-015369-72cjogxz 5348 4 were be VBD cord-015369-72cjogxz 5348 5 bleeding bleed VBG cord-015369-72cjogxz 5348 6 ( ( -LRB- cord-015369-72cjogxz 5348 7 n n NN cord-015369-72cjogxz 5348 8 ¼ ¼ NNP cord-015369-72cjogxz 5348 9 16 16 CD cord-015369-72cjogxz 5348 10 , , , cord-015369-72cjogxz 5348 11 27 27 CD cord-015369-72cjogxz 5348 12 % % NN cord-015369-72cjogxz 5348 13 ; ; , cord-015369-72cjogxz 5348 14 cannulation cannulation NN cord-015369-72cjogxz 5348 15 area area NN cord-015369-72cjogxz 5348 16 ( ( -LRB- cord-015369-72cjogxz 5348 17 n n NN cord-015369-72cjogxz 5348 18 ¼ ¼ NNP cord-015369-72cjogxz 5348 19 9 9 CD cord-015369-72cjogxz 5348 20 ) ) -RRB- cord-015369-72cjogxz 5348 21 and and CC cord-015369-72cjogxz 5348 22 hematothorax hematothorax NNP cord-015369-72cjogxz 5348 23 ( ( -LRB- cord-015369-72cjogxz 5348 24 n n NNP cord-015369-72cjogxz 5348 25 ¼ ¼ NNP cord-015369-72cjogxz 5348 26 7 7 CD cord-015369-72cjogxz 5348 27 ) ) -RRB- cord-015369-72cjogxz 5348 28 ) ) -RRB- cord-015369-72cjogxz 5348 29 and and CC cord-015369-72cjogxz 5348 30 infections infection NNS cord-015369-72cjogxz 5348 31 ( ( -LRB- cord-015369-72cjogxz 5348 32 n n CC cord-015369-72cjogxz 5348 33 ¼ ¼ NNP cord-015369-72cjogxz 5348 34 11 11 CD cord-015369-72cjogxz 5348 35 , , , cord-015369-72cjogxz 5348 36 18 18 CD cord-015369-72cjogxz 5348 37 % % NN cord-015369-72cjogxz 5348 38 ) ) -RRB- cord-015369-72cjogxz 5348 39 , , , cord-015369-72cjogxz 5348 40 ( ( -LRB- cord-015369-72cjogxz 5348 41 others other NNS cord-015369-72cjogxz 5348 42 : : : cord-015369-72cjogxz 5348 43 schreib schreib NNP cord-015369-72cjogxz 5348 44 eventuell eventuell NNP cord-015369-72cjogxz 5348 45 alle alle NNP cord-015369-72cjogxz 5348 46 in in IN cord-015369-72cjogxz 5348 47 klammer klammer NNP cord-015369-72cjogxz 5348 48 nach nach NNP cord-015369-72cjogxz 5348 49 ' ' `` cord-015369-72cjogxz 5348 50 others other NNS cord-015369-72cjogxz 5348 51 ' ' '' cord-015369-72cjogxz 5349 1 auf auf NNP cord-015369-72cjogxz 5350 1 und und NNP cord-015369-72cjogxz 5350 2 die die VB cord-015369-72cjogxz 5351 1 gesamtzahl gesamtzahl NNS cord-015369-72cjogxz 5352 1 und und IN cord-015369-72cjogxz 5352 2 % % NN cord-015369-72cjogxz 5352 3 dazu dazu NNP cord-015369-72cjogxz 5352 4 , , , cord-015369-72cjogxz 5352 5 oder oder NNP cord-015369-72cjogxz 5352 6 ganz ganz NNP cord-015369-72cjogxz 5352 7 weglassen weglassen NNP cord-015369-72cjogxz 5352 8 ) ) -RRB- cord-015369-72cjogxz 5353 1 Time time NN cord-015369-72cjogxz 5353 2 of of IN cord-015369-72cjogxz 5353 3 ECMO ECMO NNP cord-015369-72cjogxz 5353 4 implantation implantation NN cord-015369-72cjogxz 5353 5 had have VBD cord-015369-72cjogxz 5353 6 no no DT cord-015369-72cjogxz 5353 7 impact impact NN cord-015369-72cjogxz 5353 8 on on IN cord-015369-72cjogxz 5353 9 patient patient JJ cord-015369-72cjogxz 5353 10 survival survival NN cord-015369-72cjogxz 5353 11 ( ( -LRB- cord-015369-72cjogxz 5353 12 problems problem NNS cord-015369-72cjogxz 5353 13 during during IN cord-015369-72cjogxz 5353 14 weaning wean VBG cord-015369-72cjogxz 5353 15 off off RP cord-015369-72cjogxz 5353 16 bypass bypass NN cord-015369-72cjogxz 5353 17 : : : cord-015369-72cjogxz 5353 18 66 66 CD cord-015369-72cjogxz 5353 19 % % NN cord-015369-72cjogxz 5353 20 ; ; , cord-015369-72cjogxz 5353 21 inability inability NN cord-015369-72cjogxz 5353 22 to to TO cord-015369-72cjogxz 5353 23 wean wean VB cord-015369-72cjogxz 5353 24 off off RP cord-015369-72cjogxz 5353 25 bypass bypass NN cord-015369-72cjogxz 5353 26 : : : cord-015369-72cjogxz 5353 27 40 40 CD cord-015369-72cjogxz 5353 28 % % NN cord-015369-72cjogxz 5353 29 , , , cord-015369-72cjogxz 5353 30 sudden sudden JJ cord-015369-72cjogxz 5353 31 PGD PGD NNP cord-015369-72cjogxz 5353 32 in in IN cord-015369-72cjogxz 5353 33 ICU ICU NNP cord-015369-72cjogxz 5353 34 : : : cord-015369-72cjogxz 5353 35 30 30 CD cord-015369-72cjogxz 5353 36 % % NN cord-015369-72cjogxz 5353 37 ; ; : cord-015369-72cjogxz 5353 38 p p NN cord-015369-72cjogxz 5353 39 ¼ ¼ CD cord-015369-72cjogxz 5353 40 0.101 0.101 CD cord-015369-72cjogxz 5353 41 ) ) -RRB- cord-015369-72cjogxz 5354 1 Conclusions conclusion NNS cord-015369-72cjogxz 5354 2 . . . cord-015369-72cjogxz 5355 1 ECMO ECMO NNP cord-015369-72cjogxz 5355 2 is be VBZ cord-015369-72cjogxz 5355 3 a a DT cord-015369-72cjogxz 5355 4 valuable valuable JJ cord-015369-72cjogxz 5355 5 tool tool NN cord-015369-72cjogxz 5355 6 to to TO cord-015369-72cjogxz 5355 7 overcome overcome VB cord-015369-72cjogxz 5355 8 PGD PGD NNP cord-015369-72cjogxz 5355 9 after after IN cord-015369-72cjogxz 5355 10 cardiac cardiac JJ cord-015369-72cjogxz 5355 11 transplantation transplantation NN cord-015369-72cjogxz 5355 12 . . . cord-015369-72cjogxz 5356 1 Bigger big JJR cord-015369-72cjogxz 5356 2 experience experience NN cord-015369-72cjogxz 5356 3 improves improve VBZ cord-015369-72cjogxz 5356 4 results result NNS cord-015369-72cjogxz 5356 5 significantly significantly RB cord-015369-72cjogxz 5356 6 . . . cord-015369-72cjogxz 5357 1 However however RB cord-015369-72cjogxz 5357 2 , , , cord-015369-72cjogxz 5357 3 complications complication NNS cord-015369-72cjogxz 5357 4 can can MD cord-015369-72cjogxz 5357 5 occur occur VB cord-015369-72cjogxz 5357 6 and and CC cord-015369-72cjogxz 5357 7 proper proper JJ cord-015369-72cjogxz 5357 8 management management NN cord-015369-72cjogxz 5357 9 is be VBZ cord-015369-72cjogxz 5357 10 of of IN cord-015369-72cjogxz 5357 11 uttermost uttermost JJ cord-015369-72cjogxz 5357 12 importance importance NN cord-015369-72cjogxz 5357 13 . . . cord-015369-72cjogxz 5358 1 The the DT cord-015369-72cjogxz 5358 2 aim aim NN cord-015369-72cjogxz 5358 3 of of IN cord-015369-72cjogxz 5358 4 the the DT cord-015369-72cjogxz 5358 5 study study NN cord-015369-72cjogxz 5358 6 was be VBD cord-015369-72cjogxz 5358 7 to to TO cord-015369-72cjogxz 5358 8 evaluate evaluate VB cord-015369-72cjogxz 5358 9 the the DT cord-015369-72cjogxz 5358 10 pattern pattern NN cord-015369-72cjogxz 5358 11 of of IN cord-015369-72cjogxz 5358 12 brain brain NN cord-015369-72cjogxz 5358 13 natriuretic natriuretic JJ cord-015369-72cjogxz 5358 14 peptide peptide NN cord-015369-72cjogxz 5358 15 ( ( -LRB- cord-015369-72cjogxz 5358 16 BNP BNP NNP cord-015369-72cjogxz 5358 17 ) ) -RRB- cord-015369-72cjogxz 5358 18 concentration concentration NN cord-015369-72cjogxz 5358 19 in in IN cord-015369-72cjogxz 5358 20 heart heart NN cord-015369-72cjogxz 5358 21 transplant transplant NN cord-015369-72cjogxz 5358 22 ( ( -LRB- cord-015369-72cjogxz 5358 23 HTX HTX NNP cord-015369-72cjogxz 5358 24 ) ) -RRB- cord-015369-72cjogxz 5358 25 recipients recipient NNS cord-015369-72cjogxz 5358 26 and and CC cord-015369-72cjogxz 5358 27 its -PRON- PRP$ cord-015369-72cjogxz 5358 28 relation relation NN cord-015369-72cjogxz 5358 29 to to IN cord-015369-72cjogxz 5358 30 the the DT cord-015369-72cjogxz 5358 31 degree degree NN cord-015369-72cjogxz 5358 32 of of IN cord-015369-72cjogxz 5358 33 significant significant JJ cord-015369-72cjogxz 5358 34 transplant transplant NN cord-015369-72cjogxz 5358 35 coronary coronary JJ cord-015369-72cjogxz 5358 36 artery artery NN cord-015369-72cjogxz 5358 37 disease disease NN cord-015369-72cjogxz 5358 38 ( ( -LRB- cord-015369-72cjogxz 5358 39 CAV CAV NNP cord-015369-72cjogxz 5358 40 Background Background NNP cord-015369-72cjogxz 5358 41 . . . cord-015369-72cjogxz 5359 1 Minimally minimally RB cord-015369-72cjogxz 5359 2 invasive invasive JJ cord-015369-72cjogxz 5359 3 follicular follicular JJ cord-015369-72cjogxz 5359 4 thyroid thyroid NN cord-015369-72cjogxz 5359 5 carcinoma carcinoma NN cord-015369-72cjogxz 5359 6 ( ( -LRB- cord-015369-72cjogxz 5359 7 MIFTC MIFTC NNP cord-015369-72cjogxz 5359 8 ) ) -RRB- cord-015369-72cjogxz 5359 9 is be VBZ cord-015369-72cjogxz 5359 10 defined define VBN cord-015369-72cjogxz 5359 11 to to TO cord-015369-72cjogxz 5359 12 be be VB cord-015369-72cjogxz 5359 13 an an DT cord-015369-72cjogxz 5359 14 encapsulated encapsulate VBN cord-015369-72cjogxz 5359 15 tumor tumor NN cord-015369-72cjogxz 5359 16 demonstrating demonstrate VBG cord-015369-72cjogxz 5359 17 limited limited JJ cord-015369-72cjogxz 5359 18 unequivocal unequivocal JJ cord-015369-72cjogxz 5359 19 vascular vascular NN cord-015369-72cjogxz 5359 20 and/or and/or CC cord-015369-72cjogxz 5359 21 capsular capsular JJ cord-015369-72cjogxz 5359 22 invasion invasion NN cord-015369-72cjogxz 5359 23 . . . cord-015369-72cjogxz 5360 1 Considering consider VBG cord-015369-72cjogxz 5360 2 the the DT cord-015369-72cjogxz 5360 3 indolent indolent JJ cord-015369-72cjogxz 5360 4 behavior behavior NN cord-015369-72cjogxz 5360 5 of of IN cord-015369-72cjogxz 5360 6 these these DT cord-015369-72cjogxz 5360 7 tumors tumor NNS cord-015369-72cjogxz 5360 8 the the DT cord-015369-72cjogxz 5360 9 necessity necessity NN cord-015369-72cjogxz 5360 10 of of IN cord-015369-72cjogxz 5360 11 a a DT cord-015369-72cjogxz 5360 12 radical radical JJ cord-015369-72cjogxz 5360 13 treatment treatment NN cord-015369-72cjogxz 5360 14 with with IN cord-015369-72cjogxz 5360 15 routine routine JJ cord-015369-72cjogxz 5360 16 lymph lymph NN cord-015369-72cjogxz 5360 17 node node NN cord-015369-72cjogxz 5360 18 dissection dissection NN cord-015369-72cjogxz 5360 19 is be VBZ cord-015369-72cjogxz 5360 20 questionable questionable JJ cord-015369-72cjogxz 5360 21 . . . cord-015369-72cjogxz 5361 1 Methods method NNS cord-015369-72cjogxz 5361 2 . . . cord-015369-72cjogxz 5362 1 We -PRON- PRP cord-015369-72cjogxz 5362 2 evaluated evaluate VBD cord-015369-72cjogxz 5362 3 our -PRON- PRP$ cord-015369-72cjogxz 5362 4 data datum NNS cord-015369-72cjogxz 5362 5 in in IN cord-015369-72cjogxz 5362 6 2 2 CD cord-015369-72cjogxz 5362 7 periods period NNS cord-015369-72cjogxz 5362 8 of of IN cord-015369-72cjogxz 5362 9 time time NN cord-015369-72cjogxz 5362 10 focusing focus VBG cord-015369-72cjogxz 5362 11 on on IN cord-015369-72cjogxz 5362 12 the the DT cord-015369-72cjogxz 5362 13 necessity necessity NN cord-015369-72cjogxz 5362 14 of of IN cord-015369-72cjogxz 5362 15 lymph lymph NN cord-015369-72cjogxz 5362 16 node node NN cord-015369-72cjogxz 5362 17 dissection dissection NN cord-015369-72cjogxz 5362 18 in in IN cord-015369-72cjogxz 5362 19 MIFTC MIFTC NNP cord-015369-72cjogxz 5362 20 : : : cord-015369-72cjogxz 5363 1 In in IN cord-015369-72cjogxz 5363 2 the the DT cord-015369-72cjogxz 5363 3 first first JJ cord-015369-72cjogxz 5363 4 period period NN cord-015369-72cjogxz 5363 5 from from IN cord-015369-72cjogxz 5363 6 1985 1985 CD cord-015369-72cjogxz 5363 7 to to IN cord-015369-72cjogxz 5363 8 1998 1998 CD cord-015369-72cjogxz 5363 9 our -PRON- PRP$ cord-015369-72cjogxz 5363 10 pathologists pathologist NNS cord-015369-72cjogxz 5363 11 reviewed review VBD cord-015369-72cjogxz 5363 12 all all DT cord-015369-72cjogxz 5363 13 fol fol NNP cord-015369-72cjogxz 5363 14 - - HYPH cord-015369-72cjogxz 5363 15 licular licular JJ cord-015369-72cjogxz 5363 16 thyroid thyroid NN cord-015369-72cjogxz 5363 17 carcinomas carcinoma NNS cord-015369-72cjogxz 5363 18 ( ( -LRB- cord-015369-72cjogxz 5363 19 FTC FTC NNP cord-015369-72cjogxz 5363 20 ) ) -RRB- cord-015369-72cjogxz 5363 21 and and CC cord-015369-72cjogxz 5363 22 identified identify VBD cord-015369-72cjogxz 5363 23 those those DT cord-015369-72cjogxz 5363 24 tumors tumor NNS cord-015369-72cjogxz 5363 25 appropriate appropriate JJ cord-015369-72cjogxz 5363 26 to to IN cord-015369-72cjogxz 5363 27 the the DT cord-015369-72cjogxz 5363 28 criteria criterion NNS cord-015369-72cjogxz 5363 29 used use VBN cord-015369-72cjogxz 5363 30 for for IN cord-015369-72cjogxz 5363 31 diagnoses diagnosis NNS cord-015369-72cjogxz 5363 32 of of IN cord-015369-72cjogxz 5363 33 MIFTC MIFTC NNP cord-015369-72cjogxz 5363 34 . . . cord-015369-72cjogxz 5364 1 The the DT cord-015369-72cjogxz 5364 2 patients patient NNS cord-015369-72cjogxz 5364 3 were be VBD cord-015369-72cjogxz 5364 4 followed follow VBN cord-015369-72cjogxz 5364 5 for for IN cord-015369-72cjogxz 5364 6 11.6 11.6 CD cord-015369-72cjogxz 5364 7 years year NNS cord-015369-72cjogxz 5364 8 on on IN cord-015369-72cjogxz 5364 9 average average JJ cord-015369-72cjogxz 5364 10 . . . cord-015369-72cjogxz 5365 1 In in IN cord-015369-72cjogxz 5365 2 the the DT cord-015369-72cjogxz 5365 3 second second JJ cord-015369-72cjogxz 5365 4 period period NN cord-015369-72cjogxz 5365 5 from from IN cord-015369-72cjogxz 5365 6 1999 1999 CD cord-015369-72cjogxz 5365 7 to to IN cord-015369-72cjogxz 5365 8 2008 2008 CD cord-015369-72cjogxz 5366 1 we -PRON- PRP cord-015369-72cjogxz 5366 2 observed observe VBD cord-015369-72cjogxz 5366 3 all all DT cord-015369-72cjogxz 5366 4 FTCs ftc NNS cord-015369-72cjogxz 5366 5 demonstrating demonstrate VBG cord-015369-72cjogxz 5366 6 lymph lymph NN cord-015369-72cjogxz 5366 7 node node NN cord-015369-72cjogxz 5366 8 involvement involvement NN cord-015369-72cjogxz 5366 9 . . . cord-015369-72cjogxz 5367 1 Results result NNS cord-015369-72cjogxz 5367 2 . . . cord-015369-72cjogxz 5368 1 In in IN cord-015369-72cjogxz 5368 2 the the DT cord-015369-72cjogxz 5368 3 first first JJ cord-015369-72cjogxz 5368 4 group group NN cord-015369-72cjogxz 5368 5 of of IN cord-015369-72cjogxz 5368 6 43 43 CD cord-015369-72cjogxz 5368 7 patients patient NNS cord-015369-72cjogxz 5368 8 affected affect VBN cord-015369-72cjogxz 5368 9 with with IN cord-015369-72cjogxz 5368 10 MIFTC MIFTC NNP cord-015369-72cjogxz 5369 1 no no DT cord-015369-72cjogxz 5369 2 lymph lymph NN cord-015369-72cjogxz 5369 3 node node NN cord-015369-72cjogxz 5369 4 metastases metastasis NNS cord-015369-72cjogxz 5369 5 could could MD cord-015369-72cjogxz 5369 6 be be VB cord-015369-72cjogxz 5369 7 detected detect VBN cord-015369-72cjogxz 5369 8 neither neither CC cord-015369-72cjogxz 5369 9 at at IN cord-015369-72cjogxz 5369 10 time time NN cord-015369-72cjogxz 5369 11 of of IN cord-015369-72cjogxz 5369 12 diagnosis diagnosis NN cord-015369-72cjogxz 5369 13 nor nor CC cord-015369-72cjogxz 5369 14 during during IN cord-015369-72cjogxz 5369 15 follow follow NN cord-015369-72cjogxz 5369 16 - - HYPH cord-015369-72cjogxz 5369 17 up up RP cord-015369-72cjogxz 5369 18 time time NN cord-015369-72cjogxz 5369 19 . . . cord-015369-72cjogxz 5370 1 No no DT cord-015369-72cjogxz 5370 2 distant distant JJ cord-015369-72cjogxz 5370 3 metastases metastasis NNS cord-015369-72cjogxz 5370 4 or or CC cord-015369-72cjogxz 5370 5 recurrent recurrent JJ cord-015369-72cjogxz 5370 6 diseases disease NNS cord-015369-72cjogxz 5370 7 were be VBD cord-015369-72cjogxz 5370 8 observed observe VBN cord-015369-72cjogxz 5370 9 . . . cord-015369-72cjogxz 5371 1 The the DT cord-015369-72cjogxz 5371 2 few few JJ cord-015369-72cjogxz 5371 3 tumors tumor NNS cord-015369-72cjogxz 5371 4 of of IN cord-015369-72cjogxz 5371 5 the the DT cord-015369-72cjogxz 5371 6 second second JJ cord-015369-72cjogxz 5371 7 period period NN cord-015369-72cjogxz 5371 8 inducing induce VBG cord-015369-72cjogxz 5371 9 lymph lymph NN cord-015369-72cjogxz 5371 10 node node NN cord-015369-72cjogxz 5371 11 metastases metastasis NNS cord-015369-72cjogxz 5371 12 were be VBD cord-015369-72cjogxz 5371 13 all all DT cord-015369-72cjogxz 5371 14 of of IN cord-015369-72cjogxz 5371 15 widely widely RB cord-015369-72cjogxz 5371 16 invasive invasive JJ cord-015369-72cjogxz 5371 17 pattern pattern NN cord-015369-72cjogxz 5371 18 of of IN cord-015369-72cjogxz 5371 19 growth growth NN cord-015369-72cjogxz 5371 20 , , , cord-015369-72cjogxz 5371 21 none none NN cord-015369-72cjogxz 5371 22 of of IN cord-015369-72cjogxz 5371 23 them -PRON- PRP cord-015369-72cjogxz 5371 24 was be VBD cord-015369-72cjogxz 5371 25 minimally minimally RB cord-015369-72cjogxz 5371 26 invasive invasive JJ cord-015369-72cjogxz 5371 27 . . . cord-015369-72cjogxz 5372 1 Conclusions conclusion NNS cord-015369-72cjogxz 5372 2 . . . cord-015369-72cjogxz 5373 1 Lymph lymph NN cord-015369-72cjogxz 5373 2 node node NN cord-015369-72cjogxz 5373 3 involvement involvement NN cord-015369-72cjogxz 5373 4 is be VBZ cord-015369-72cjogxz 5373 5 generally generally RB cord-015369-72cjogxz 5373 6 rare rare JJ cord-015369-72cjogxz 5373 7 in in IN cord-015369-72cjogxz 5373 8 FTC FTC NNP cord-015369-72cjogxz 5373 9 . . . cord-015369-72cjogxz 5374 1 The the DT cord-015369-72cjogxz 5374 2 absence absence NN cord-015369-72cjogxz 5374 3 of of IN cord-015369-72cjogxz 5374 4 lymph lymph NN cord-015369-72cjogxz 5374 5 node node NN cord-015369-72cjogxz 5374 6 metastases metastasis NNS cord-015369-72cjogxz 5374 7 in in IN cord-015369-72cjogxz 5374 8 our -PRON- PRP$ cord-015369-72cjogxz 5374 9 series series NN cord-015369-72cjogxz 5374 10 suggests suggest VBZ cord-015369-72cjogxz 5374 11 no no DT cord-015369-72cjogxz 5374 12 need need NN cord-015369-72cjogxz 5374 13 for for IN cord-015369-72cjogxz 5374 14 lymphadenectomy lymphadenectomy NN cord-015369-72cjogxz 5374 15 in in IN cord-015369-72cjogxz 5374 16 MIFTC MIFTC NNP cord-015369-72cjogxz 5374 17 . . . cord-015369-72cjogxz 5375 1 We -PRON- PRP cord-015369-72cjogxz 5375 2 present present VBP cord-015369-72cjogxz 5375 3 an an DT cord-015369-72cjogxz 5375 4 unusual unusual JJ cord-015369-72cjogxz 5375 5 case case NN cord-015369-72cjogxz 5375 6 of of IN cord-015369-72cjogxz 5375 7 a a DT cord-015369-72cjogxz 5375 8 metastatic metastatic JJ cord-015369-72cjogxz 5375 9 thyroid thyroid NN cord-015369-72cjogxz 5375 10 tumor tumor NN cord-015369-72cjogxz 5375 11 , , , cord-015369-72cjogxz 5375 12 of of IN cord-015369-72cjogxz 5375 13 which which WDT cord-015369-72cjogxz 5375 14 the the DT cord-015369-72cjogxz 5375 15 primary primary JJ cord-015369-72cjogxz 5375 16 cancer cancer NN cord-015369-72cjogxz 5375 17 was be VBD cord-015369-72cjogxz 5375 18 an an DT cord-015369-72cjogxz 5375 19 infiltrative infiltrative JJ cord-015369-72cjogxz 5375 20 high high JJ cord-015369-72cjogxz 5375 21 grade grade NN cord-015369-72cjogxz 5375 22 transitional transitional JJ cord-015369-72cjogxz 5375 23 cell cell NN cord-015369-72cjogxz 5375 24 carcinoma carcinoma NN cord-015369-72cjogxz 5375 25 of of IN cord-015369-72cjogxz 5375 26 the the DT cord-015369-72cjogxz 5375 27 urinary urinary JJ cord-015369-72cjogxz 5375 28 bladder bladder NN cord-015369-72cjogxz 5375 29 . . . cord-015369-72cjogxz 5376 1 The the DT cord-015369-72cjogxz 5376 2 time time NN cord-015369-72cjogxz 5376 3 from from IN cord-015369-72cjogxz 5376 4 the the DT cord-015369-72cjogxz 5376 5 diagnosis diagnosis NN cord-015369-72cjogxz 5376 6 of of IN cord-015369-72cjogxz 5376 7 primary primary JJ cord-015369-72cjogxz 5376 8 tumor tumor NN cord-015369-72cjogxz 5376 9 to to IN cord-015369-72cjogxz 5376 10 metastasis metastasis NN cord-015369-72cjogxz 5376 11 was be VBD cord-015369-72cjogxz 5376 12 13 13 CD cord-015369-72cjogxz 5376 13 months month NNS cord-015369-72cjogxz 5376 14 . . . cord-015369-72cjogxz 5377 1 The the DT cord-015369-72cjogxz 5377 2 appearance appearance NN cord-015369-72cjogxz 5377 3 of of IN cord-015369-72cjogxz 5377 4 the the DT cord-015369-72cjogxz 5377 5 thyroid thyroid NN cord-015369-72cjogxz 5377 6 metastasis metastasis NN cord-015369-72cjogxz 5377 7 was be VBD cord-015369-72cjogxz 5377 8 like like IN cord-015369-72cjogxz 5377 9 a a DT cord-015369-72cjogxz 5377 10 primary primary JJ cord-015369-72cjogxz 5377 11 thyroid thyroid NN cord-015369-72cjogxz 5377 12 disease disease NN cord-015369-72cjogxz 5377 13 . . . cord-015369-72cjogxz 5378 1 Diagnosis diagnosis NN cord-015369-72cjogxz 5378 2 of of IN cord-015369-72cjogxz 5378 3 thyroid thyroid NN cord-015369-72cjogxz 5378 4 metastasis metastasis NN cord-015369-72cjogxz 5378 5 as as IN cord-015369-72cjogxz 5378 6 a a DT cord-015369-72cjogxz 5378 7 consequence consequence NN cord-015369-72cjogxz 5378 8 of of IN cord-015369-72cjogxz 5378 9 urinary urinary JJ cord-015369-72cjogxz 5378 10 bladder bladder NN cord-015369-72cjogxz 5378 11 carcinoma carcinoma NN cord-015369-72cjogxz 5378 12 was be VBD cord-015369-72cjogxz 5378 13 confirmed confirm VBN cord-015369-72cjogxz 5378 14 by by IN cord-015369-72cjogxz 5378 15 intraoperative intraoperative JJ cord-015369-72cjogxz 5378 16 biopsy biopsy NN cord-015369-72cjogxz 5378 17 , , , cord-015369-72cjogxz 5378 18 histopathological histopathological JJ cord-015369-72cjogxz 5378 19 and and CC cord-015369-72cjogxz 5378 20 immunohistochemical immunohistochemical JJ cord-015369-72cjogxz 5378 21 findings finding NNS cord-015369-72cjogxz 5378 22 . . . cord-015369-72cjogxz 5379 1 The the DT cord-015369-72cjogxz 5379 2 treatment treatment NN cord-015369-72cjogxz 5379 3 consisted consist VBD cord-015369-72cjogxz 5379 4 of of IN cord-015369-72cjogxz 5379 5 radical radical JJ cord-015369-72cjogxz 5379 6 thyroidectomy thyroidectomy NN cord-015369-72cjogxz 5379 7 in in IN cord-015369-72cjogxz 5379 8 addition addition NN cord-015369-72cjogxz 5379 9 to to IN cord-015369-72cjogxz 5379 10 systemic systemic JJ cord-015369-72cjogxz 5379 11 adjuvant adjuvant JJ cord-015369-72cjogxz 5379 12 chemotherapy chemotherapy NN cord-015369-72cjogxz 5379 13 . . . cord-015369-72cjogxz 5380 1 Report report NN cord-015369-72cjogxz 5380 2 after after IN cord-015369-72cjogxz 5380 3 1-year 1-year CD cord-015369-72cjogxz 5380 4 follow follow VBP cord-015369-72cjogxz 5380 5 up up RP cord-015369-72cjogxz 5380 6 . . . cord-015369-72cjogxz 5381 1 Diagnosis diagnosis NN cord-015369-72cjogxz 5381 2 of of IN cord-015369-72cjogxz 5381 3 Hashimoto Hashimoto NNP cord-015369-72cjogxz 5381 4 's 's POS cord-015369-72cjogxz 5381 5 thyroiditis thyroiditis NN cord-015369-72cjogxz 5381 6 : : : cord-015369-72cjogxz 5381 7 Discrepancy discrepancy NN cord-015369-72cjogxz 5381 8 between between IN cord-015369-72cjogxz 5381 9 preoperative preoperative JJ cord-015369-72cjogxz 5381 10 antiTPO antiTPO NNS cord-015369-72cjogxz 5381 11 - - HYPH cord-015369-72cjogxz 5381 12 autoantibodies autoantibody NNS cord-015369-72cjogxz 5381 13 and and CC cord-015369-72cjogxz 5381 14 histological histological JJ cord-015369-72cjogxz 5381 15 grading grading NN cord-015369-72cjogxz 5381 16 in in IN cord-015369-72cjogxz 5381 17 thyroid thyroid NN cord-015369-72cjogxz 5381 18 tissue tissue NN cord-015369-72cjogxz 5381 19 Methodik Methodik NNP cord-015369-72cjogxz 5381 20 . . . cord-015369-72cjogxz 5382 1 Bei Bei NNP cord-015369-72cjogxz 5382 2 320 320 CD cord-015369-72cjogxz 5383 1 konsekutiven konsekutiven NNP cord-015369-72cjogxz 5383 2 weiblichen weiblichen NNP cord-015369-72cjogxz 5383 3 Patienten Patienten NNP cord-015369-72cjogxz 5383 4 wurden wurden VBD cord-015369-72cjogxz 5383 5 vor vor NNP cord-015369-72cjogxz 5383 6 der der NNP cord-015369-72cjogxz 5383 7 Schilddrüsenoperation Schilddrüsenoperation NNP cord-015369-72cjogxz 5383 8 prospektiv prospektiv JJ cord-015369-72cjogxz 5384 1 präoperative präoperative NNP cord-015369-72cjogxz 5384 2 anti anti JJ cord-015369-72cjogxz 5384 3 - - JJ cord-015369-72cjogxz 5384 4 TPO TPO NNP cord-015369-72cjogxz 5384 5 - - HYPH cord-015369-72cjogxz 5384 6 Bestimmungen Bestimmungen NNP cord-015369-72cjogxz 5384 7 durchgeführt durchgeführt NN cord-015369-72cjogxz 5384 8 und und IN cord-015369-72cjogxz 5384 9 bei bei NNP cord-015369-72cjogxz 5384 10 der der NNP cord-015369-72cjogxz 5384 11 histologischen histologischen NNP cord-015369-72cjogxz 5384 12 Aufarbeitung Aufarbeitung NNP cord-015369-72cjogxz 5384 13 speziell speziell NNP cord-015369-72cjogxz 5384 14 auf auf NNP cord-015369-72cjogxz 5384 15 die die VBP cord-015369-72cjogxz 5384 16 Bewertung Bewertung NNP cord-015369-72cjogxz 5384 17 der der NNP cord-015369-72cjogxz 5385 1 lymphozytären lymphozytären NNP cord-015369-72cjogxz 5385 2 Infiltration Infiltration NNP cord-015369-72cjogxz 5385 3 und und NNP cord-015369-72cjogxz 5385 4 der der NNP cord-015369-72cjogxz 5385 5 Graduierung Graduierung NNP cord-015369-72cjogxz 5385 6 ( ( -LRB- cord-015369-72cjogxz 5385 7 Grad Grad NNP cord-015369-72cjogxz 5385 8 1 1 CD cord-015369-72cjogxz 5385 9 - - SYM cord-015369-72cjogxz 5385 10 4 4 CD cord-015369-72cjogxz 5385 11 ) ) -RRB- cord-015369-72cjogxz 5385 12 geachtet geachtet NNP cord-015369-72cjogxz 5385 13 . . . cord-015369-72cjogxz 5386 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 5386 2 . . . cord-015369-72cjogxz 5387 1 55 55 CD cord-015369-72cjogxz 5387 2 von von NNP cord-015369-72cjogxz 5387 3 320 320 CD cord-015369-72cjogxz 5388 1 ( ( -LRB- cord-015369-72cjogxz 5388 2 17,2 17,2 CD cord-015369-72cjogxz 5388 3 % % NN cord-015369-72cjogxz 5388 4 ) ) -RRB- cord-015369-72cjogxz 5389 1 Patienten Patienten NNP cord-015369-72cjogxz 5389 2 wiesen wiesen NNP cord-015369-72cjogxz 5389 3 präoperativ präoperativ NNP cord-015369-72cjogxz 5389 4 erhöhte erhöhte NNP cord-015369-72cjogxz 5390 1 antiTPO antiTPO NNP cord-015369-72cjogxz 5390 2 - - : cord-015369-72cjogxz 5390 3 Spiegel Spiegel NNP cord-015369-72cjogxz 5390 4 auf auf NNP cord-015369-72cjogxz 5390 5 , , , cord-015369-72cjogxz 5390 6 130 130 CD cord-015369-72cjogxz 5390 7 von von NNP cord-015369-72cjogxz 5390 8 320 320 CD cord-015369-72cjogxz 5390 9 ( ( -LRB- cord-015369-72cjogxz 5390 10 40,6 40,6 CD cord-015369-72cjogxz 5390 11 % % NN cord-015369-72cjogxz 5390 12 ) ) -RRB- cord-015369-72cjogxz 5391 1 histologische histologische NN cord-015369-72cjogxz 5391 2 Zeichen Zeichen NNP cord-015369-72cjogxz 5391 3 einer einer NNP cord-015369-72cjogxz 5391 4 Thyreoiditis Thyreoiditis NNP cord-015369-72cjogxz 5391 5 . . . cord-015369-72cjogxz 5392 1 Bei Bei NNP cord-015369-72cjogxz 5392 2 den den NNP cord-015369-72cjogxz 5393 1 antiTPO antiTPO NNP cord-015369-72cjogxz 5393 2 - - HYPH cord-015369-72cjogxz 5393 3 positiven positiven NNP cord-015369-72cjogxz 5393 4 Patienten Patienten NNP cord-015369-72cjogxz 5393 5 wiesen wiesen VBD cord-015369-72cjogxz 5393 6 10 10 CD cord-015369-72cjogxz 5393 7 Grad Grad NNP cord-015369-72cjogxz 5393 8 1 1 CD cord-015369-72cjogxz 5393 9 , , , cord-015369-72cjogxz 5393 10 26 26 CD cord-015369-72cjogxz 5393 11 Grad Grad NNP cord-015369-72cjogxz 5393 12 2 2 CD cord-015369-72cjogxz 5393 13 , , , cord-015369-72cjogxz 5393 14 4 4 CD cord-015369-72cjogxz 5393 15 Grad grad NN cord-015369-72cjogxz 5393 16 3 3 CD cord-015369-72cjogxz 5394 1 und und IN cord-015369-72cjogxz 5394 2 10 10 CD cord-015369-72cjogxz 5394 3 Grad Grad NNP cord-015369-72cjogxz 5394 4 4 4 CD cord-015369-72cjogxz 5394 5 auf auf NNP cord-015369-72cjogxz 5394 6 , , , cord-015369-72cjogxz 5394 7 5 5 CD cord-015369-72cjogxz 5394 8 zeigten zeigten NNP cord-015369-72cjogxz 5394 9 keine keine NNP cord-015369-72cjogxz 5394 10 lymphozytäre lymphozytäre NNP cord-015369-72cjogxz 5394 11 Infiltration Infiltration NNP cord-015369-72cjogxz 5394 12 . . . cord-015369-72cjogxz 5395 1 Bei Bei NNP cord-015369-72cjogxz 5395 2 jenen jenen NNP cord-015369-72cjogxz 5395 3 80 80 CD cord-015369-72cjogxz 5395 4 Patienten Patienten NNP cord-015369-72cjogxz 5395 5 mit mit VBP cord-015369-72cjogxz 5395 6 his -PRON- PRP$ cord-015369-72cjogxz 5395 7 - - HYPH cord-015369-72cjogxz 5395 8 tologischen tologischen NNP cord-015369-72cjogxz 5396 1 Entzündungszeichen Entzündungszeichen NNP cord-015369-72cjogxz 5396 2 ohne ohne NNP cord-015369-72cjogxz 5397 1 pathologischem pathologischem NNP cord-015369-72cjogxz 5398 1 antiTPO antiTPO NNP cord-015369-72cjogxz 5398 2 - - HYPH cord-015369-72cjogxz 5398 3 Spiegel Spiegel NNP cord-015369-72cjogxz 5398 4 wurde wurde NN cord-015369-72cjogxz 5398 5 Grad Grad NNP cord-015369-72cjogxz 5398 6 1 1 CD cord-015369-72cjogxz 5398 7 in in IN cord-015369-72cjogxz 5398 8 62 62 CD cord-015369-72cjogxz 5398 9 , , , cord-015369-72cjogxz 5398 10 Grad Grad NNP cord-015369-72cjogxz 5398 11 2 2 CD cord-015369-72cjogxz 5398 12 in in IN cord-015369-72cjogxz 5398 13 17 17 CD cord-015369-72cjogxz 5399 1 und und IN cord-015369-72cjogxz 5399 2 Grad Grad NNP cord-015369-72cjogxz 5399 3 3 3 CD cord-015369-72cjogxz 5399 4 in in IN cord-015369-72cjogxz 5399 5 1 1 CD cord-015369-72cjogxz 5399 6 Fällen Fällen NNP cord-015369-72cjogxz 5399 7 gefunden gefunden NN cord-015369-72cjogxz 5399 8 , , , cord-015369-72cjogxz 5399 9 kein kein NNP cord-015369-72cjogxz 5399 10 Patient Patient NNP cord-015369-72cjogxz 5399 11 wies wies NNP cord-015369-72cjogxz 5399 12 Grad Grad NNP cord-015369-72cjogxz 5399 13 4 4 CD cord-015369-72cjogxz 5399 14 auf auf NNS cord-015369-72cjogxz 5399 15 . . . cord-015369-72cjogxz 5400 1 Der Der NNP cord-015369-72cjogxz 5400 2 Schweregrad Schweregrad NNP cord-015369-72cjogxz 5400 3 der der NN cord-015369-72cjogxz 5400 4 Thyreoiditis Thyreoiditis NNP cord-015369-72cjogxz 5400 5 zeigte zeigte XX cord-015369-72cjogxz 5401 1 eine eine NNP cord-015369-72cjogxz 5401 2 signifikante signifikante NNP cord-015369-72cjogxz 5401 3 positive positive JJ cord-015369-72cjogxz 5401 4 Korrelation Korrelation NNP cord-015369-72cjogxz 5402 1 ( ( -LRB- cord-015369-72cjogxz 5402 2 p p NN cord-015369-72cjogxz 5402 3 < < XX cord-015369-72cjogxz 5402 4 0,01 0,01 XX cord-015369-72cjogxz 5402 5 ; ; : cord-015369-72cjogxz 5402 6 r r NNP cord-015369-72cjogxz 5402 7 ¼ ¼ NNP cord-015369-72cjogxz 5402 8 0,579 0,579 CD cord-015369-72cjogxz 5402 9 ) ) -RRB- cord-015369-72cjogxz 5402 10 mit mit NNP cord-015369-72cjogxz 5402 11 der der NNP cord-015369-72cjogxz 5402 12 Höhe Höhe NNP cord-015369-72cjogxz 5402 13 der der NNP cord-015369-72cjogxz 5402 14 antiTPO antiTPO NNP cord-015369-72cjogxz 5402 15 - - HYPH cord-015369-72cjogxz 5402 16 Spiegel Spiegel NNP cord-015369-72cjogxz 5402 17 . . . cord-015369-72cjogxz 5403 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 5403 2 . . . cord-015369-72cjogxz 5404 1 Nur nur UH cord-015369-72cjogxz 5405 1 40 40 CD cord-015369-72cjogxz 5405 2 % % NN cord-015369-72cjogxz 5405 3 der der NNP cord-015369-72cjogxz 5405 4 histologisch histologisch NNP cord-015369-72cjogxz 5405 5 verifizierten verifizierten NNP cord-015369-72cjogxz 5406 1 Thyreoiditis Thyreoiditis NNP cord-015369-72cjogxz 5406 2 - - HYPH cord-015369-72cjogxz 5406 3 Patienten Patienten NNP cord-015369-72cjogxz 5406 4 konnten konnten NNP cord-015369-72cjogxz 5407 1 präoperativ präoperativ NNP cord-015369-72cjogxz 5408 1 durch durch NNP cord-015369-72cjogxz 5408 2 serologische serologische NNP cord-015369-72cjogxz 5409 1 antiTPO antiTPO NNP cord-015369-72cjogxz 5409 2 - - HYPH cord-015369-72cjogxz 5409 3 Bestimmung Bestimmung NNP cord-015369-72cjogxz 5409 4 erkannt erkannt JJ cord-015369-72cjogxz 5409 5 werden werden NNP cord-015369-72cjogxz 5409 6 . . . cord-015369-72cjogxz 5410 1 Die die VB cord-015369-72cjogxz 5410 2 Daten Daten NNP cord-015369-72cjogxz 5410 3 zeigen zeigen NNP cord-015369-72cjogxz 5410 4 , , , cord-015369-72cjogxz 5410 5 dass dass NNP cord-015369-72cjogxz 5410 6 speziell speziell NNP cord-015369-72cjogxz 5410 7 die die VBP cord-015369-72cjogxz 5411 1 milden milden NNP cord-015369-72cjogxz 5411 2 Verlaufsformen Verlaufsformen NNP cord-015369-72cjogxz 5411 3 der der NNP cord-015369-72cjogxz 5411 4 Thyreoiditis Thyreoiditis NNP cord-015369-72cjogxz 5411 5 Hashimoto Hashimoto NNP cord-015369-72cjogxz 5412 1 serologisch serologisch NNP cord-015369-72cjogxz 5412 2 nicht nicht NNP cord-015369-72cjogxz 5412 3 verlässlich verlässlich NNP cord-015369-72cjogxz 5413 1 zu zu NNP cord-015369-72cjogxz 5413 2 diagnostizieren diagnostizieren NNP cord-015369-72cjogxz 5413 3 sind sind NNP cord-015369-72cjogxz 5413 4 . . . cord-015369-72cjogxz 5414 1 Late late JJ cord-015369-72cjogxz 5414 2 onset onset NN cord-015369-72cjogxz 5414 3 paralysis paralysis NN cord-015369-72cjogxz 5414 4 of of IN cord-015369-72cjogxz 5414 5 the the DT cord-015369-72cjogxz 5414 6 recurrent recurrent JJ cord-015369-72cjogxz 5414 7 laryngeal laryngeal NN cord-015369-72cjogxz 5414 8 nerve nerve NN cord-015369-72cjogxz 5414 9 after after IN cord-015369-72cjogxz 5414 10 thyroidectomya thyroidectomya NN cord-015369-72cjogxz 5414 11 rare rare JJ cord-015369-72cjogxz 5414 12 phenomenon phenomenon NN cord-015369-72cjogxz 5414 13 Grundlagen Grundlagen NNP cord-015369-72cjogxz 5414 14 . . . cord-015369-72cjogxz 5415 1 Nach Nach NNP cord-015369-72cjogxz 5415 2 postoperativ postoperativ JJ cord-015369-72cjogxz 5415 3 regulärer regulärer NN cord-015369-72cjogxz 5415 4 Stimmbandfunktion Stimmbandfunktion NNP cord-015369-72cjogxz 5415 5 kann kann NNP cord-015369-72cjogxz 5415 6 es es NNP cord-015369-72cjogxz 5415 7 in in IN cord-015369-72cjogxz 5415 8 seltenen seltenen NNP cord-015369-72cjogxz 5415 9 Fällen Fällen NNP cord-015369-72cjogxz 5415 10 auch auch NNP cord-015369-72cjogxz 5416 1 erst erst NNP cord-015369-72cjogxz 5417 1 i -PRON- PRP cord-015369-72cjogxz 5417 2 m be VBP cord-015369-72cjogxz 5417 3 spätpostoperativen spätpostoperativen NNP cord-015369-72cjogxz 5418 1 Verlauf Verlauf NNP cord-015369-72cjogxz 5418 2 zum zum VBP cord-015369-72cjogxz 5418 3 Auftreten Auftreten NNP cord-015369-72cjogxz 5419 1 einer einer NNP cord-015369-72cjogxz 5419 2 Recurrensparese Recurrensparese NNP cord-015369-72cjogxz 5419 3 kommen kommen NNP cord-015369-72cjogxz 5419 4 . . . cord-015369-72cjogxz 5420 1 Da Da NNP cord-015369-72cjogxz 5420 2 dieses dieses NNP cord-015369-72cjogxz 5420 3 Phänomen Phänomen NNP cord-015369-72cjogxz 5420 4 in in IN cord-015369-72cjogxz 5420 5 der der NNP cord-015369-72cjogxz 5420 6 Literatur Literatur NNP cord-015369-72cjogxz 5420 7 nur nur NNP cord-015369-72cjogxz 5420 8 kasuistisch kasuistisch NNP cord-015369-72cjogxz 5420 9 beschrieben beschrieben NNP cord-015369-72cjogxz 5420 10 ist ist NNP cord-015369-72cjogxz 5420 11 , , , cord-015369-72cjogxz 5420 12 wird wird NNP cord-015369-72cjogxz 5420 13 hier hier NNP cord-015369-72cjogxz 5420 14 über über NNP cord-015369-72cjogxz 5420 15 eine eine NNP cord-015369-72cjogxz 5420 16 Patientenserie Patientenserie NNP cord-015369-72cjogxz 5420 17 berichtet berichtet NNP cord-015369-72cjogxz 5420 18 . . . cord-015369-72cjogxz 5421 1 Methodik Methodik NNP cord-015369-72cjogxz 5421 2 . . . cord-015369-72cjogxz 5422 1 Vor Vor NNP cord-015369-72cjogxz 5422 2 und und IN cord-015369-72cjogxz 5422 3 nach nach NNP cord-015369-72cjogxz 5422 4 Schilddrüsenoperation Schilddrüsenoperation NNP cord-015369-72cjogxz 5422 5 wird wird NNP cord-015369-72cjogxz 5422 6 standardisiert standardisiert NNP cord-015369-72cjogxz 5423 1 eine eine NNP cord-015369-72cjogxz 5423 2 laryngologische laryngologische NN cord-015369-72cjogxz 5423 3 Untersuchung Untersuchung NNP cord-015369-72cjogxz 5423 4 an an DT cord-015369-72cjogxz 5423 5 der der NN cord-015369-72cjogxz 5423 6 eigenen eigenen NNP cord-015369-72cjogxz 5424 1 HNO HNO NNP cord-015369-72cjogxz 5424 2 - - HYPH cord-015369-72cjogxz 5424 3 Ambulanz Ambulanz NNP cord-015369-72cjogxz 5424 4 durchgeführt durchgeführt NN cord-015369-72cjogxz 5424 5 . . . cord-015369-72cjogxz 5425 1 Jene Jene NNP cord-015369-72cjogxz 5425 2 Patientin Patientin NNP cord-015369-72cjogxz 5425 3 , , , cord-015369-72cjogxz 5425 4 die die VB cord-015369-72cjogxz 5425 5 unsere unsere NNP cord-015369-72cjogxz 5425 6 Abteilung Abteilung NNP cord-015369-72cjogxz 5425 7 -nach -nach NNP cord-015369-72cjogxz 5425 8 unauffälligem unauffälligem NNS cord-015369-72cjogxz 5426 1 postoperativen postoperativen NNP cord-015369-72cjogxz 5426 2 HNO HNO NNP cord-015369-72cjogxz 5426 3 - - HYPH cord-015369-72cjogxz 5426 4 Befund Befund NNP cord-015369-72cjogxz 5426 5 - - HYPH cord-015369-72cjogxz 5426 6 wegen wegen NNP cord-015369-72cjogxz 5426 7 spätpostoperativ spätpostoperativ NN cord-015369-72cjogxz 5426 8 einsetzender einsetzender NNP cord-015369-72cjogxz 5426 9 Stimmstörung Stimmstörung NNP cord-015369-72cjogxz 5426 10 aufsuchen aufsuchen NNP cord-015369-72cjogxz 5426 11 , , , cord-015369-72cjogxz 5426 12 wurden wurden NNP cord-015369-72cjogxz 5426 13 analysiert analysiert NNP cord-015369-72cjogxz 5426 14 . . . cord-015369-72cjogxz 5427 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 5427 2 Background Background NNP cord-015369-72cjogxz 5427 3 . . . cord-015369-72cjogxz 5428 1 Objective objective JJ cord-015369-72cjogxz 5428 2 cosmetic cosmetic JJ cord-015369-72cjogxz 5428 3 analyses analysis NNS cord-015369-72cjogxz 5428 4 are be VBP cord-015369-72cjogxz 5428 5 important important JJ cord-015369-72cjogxz 5428 6 to to TO cord-015369-72cjogxz 5428 7 reproducibly reproducibly RB cord-015369-72cjogxz 5428 8 evaluate evaluate VB cord-015369-72cjogxz 5428 9 the the DT cord-015369-72cjogxz 5428 10 cosmetic cosmetic JJ cord-015369-72cjogxz 5428 11 outcome outcome NN cord-015369-72cjogxz 5428 12 after after IN cord-015369-72cjogxz 5428 13 breast breast NN cord-015369-72cjogxz 5428 14 surgery surgery NN cord-015369-72cjogxz 5428 15 and and CC cord-015369-72cjogxz 5428 16 radiotherapy radiotherapy NN cord-015369-72cjogxz 5428 17 . . . cord-015369-72cjogxz 5429 1 So so RB cord-015369-72cjogxz 5429 2 far far RB cord-015369-72cjogxz 5429 3 , , , cord-015369-72cjogxz 5429 4 only only RB cord-015369-72cjogxz 5429 5 subjective subjective JJ cord-015369-72cjogxz 5429 6 irreproducible irreproducible JJ cord-015369-72cjogxz 5429 7 scores score NNS cord-015369-72cjogxz 5429 8 have have VBP cord-015369-72cjogxz 5429 9 been be VBN cord-015369-72cjogxz 5429 10 used use VBN cord-015369-72cjogxz 5429 11 such such JJ cord-015369-72cjogxz 5429 12 as as IN cord-015369-72cjogxz 5429 13 the the DT cord-015369-72cjogxz 5429 14 Harris Harris NNP cord-015369-72cjogxz 5429 15 scale scale NN cord-015369-72cjogxz 5429 16 . . . cord-015369-72cjogxz 5430 1 We -PRON- PRP cord-015369-72cjogxz 5430 2 have have VBP cord-015369-72cjogxz 5430 3 developed develop VBN cord-015369-72cjogxz 5430 4 an an DT cord-015369-72cjogxz 5430 5 objective objective JJ cord-015369-72cjogxz 5430 6 tool tool NN cord-015369-72cjogxz 5430 7 to to TO cord-015369-72cjogxz 5430 8 reproducible reproducible JJ cord-015369-72cjogxz 5430 9 analyse analyse VB cord-015369-72cjogxz 5430 10 digital digital JJ cord-015369-72cjogxz 5430 11 pictures picture NNS cord-015369-72cjogxz 5430 12 , , , cord-015369-72cjogxz 5430 13 the the DT cord-015369-72cjogxz 5430 14 ' ' '' cord-015369-72cjogxz 5430 15 ' ' `` cord-015369-72cjogxz 5430 16 breast breast NN cord-015369-72cjogxz 5430 17 analysing analysing NN cord-015369-72cjogxz 5430 18 tool tool NN cord-015369-72cjogxz 5430 19 ' ' '' cord-015369-72cjogxz 5430 20 ' ' '' cord-015369-72cjogxz 5430 21 ( ( -LRB- cord-015369-72cjogxz 5430 22 BAT bat NN cord-015369-72cjogxz 5430 23 ) ) -RRB- cord-015369-72cjogxz 5430 24 . . . cord-015369-72cjogxz 5431 1 The the DT cord-015369-72cjogxz 5431 2 aim aim NN cord-015369-72cjogxz 5431 3 of of IN cord-015369-72cjogxz 5431 4 this this DT cord-015369-72cjogxz 5431 5 study study NN cord-015369-72cjogxz 5431 6 was be VBD cord-015369-72cjogxz 5431 7 to to TO cord-015369-72cjogxz 5431 8 compare compare VB cord-015369-72cjogxz 5431 9 subjective subjective JJ cord-015369-72cjogxz 5431 10 with with IN cord-015369-72cjogxz 5431 11 objective objective JJ cord-015369-72cjogxz 5431 12 breast breast NN cord-015369-72cjogxz 5431 13 cosmesis cosmesis NNP cord-015369-72cjogxz 5431 14 scores score NNS cord-015369-72cjogxz 5431 15 . . . cord-015369-72cjogxz 5432 1 Methods method NNS cord-015369-72cjogxz 5432 2 . . . cord-015369-72cjogxz 5433 1 Digital Digital NNP cord-015369-72cjogxz 5433 2 pictures picture NNS cord-015369-72cjogxz 5433 3 ( ( -LRB- cord-015369-72cjogxz 5433 4 frontal frontal JJ cord-015369-72cjogxz 5433 5 view view NN cord-015369-72cjogxz 5433 6 ) ) -RRB- cord-015369-72cjogxz 5433 7 from from IN cord-015369-72cjogxz 5433 8 129 129 CD cord-015369-72cjogxz 5433 9 breast breast NN cord-015369-72cjogxz 5433 10 cancer cancer NN cord-015369-72cjogxz 5433 11 patients patient NNS cord-015369-72cjogxz 5433 12 ( ( -LRB- cord-015369-72cjogxz 5433 13 60 60 CD cord-015369-72cjogxz 5433 14 from from IN cord-015369-72cjogxz 5433 15 Porto Porto NNP cord-015369-72cjogxz 5433 16 and and CC cord-015369-72cjogxz 5433 17 69 69 CD cord-015369-72cjogxz 5433 18 from from IN cord-015369-72cjogxz 5433 19 Vienna Vienna NNP cord-015369-72cjogxz 5433 20 ) ) -RRB- cord-015369-72cjogxz 5434 1 after after IN cord-015369-72cjogxz 5434 2 breast breast NN cord-015369-72cjogxz 5434 3 conserving conserve VBG cord-015369-72cjogxz 5434 4 therapy therapy NN cord-015369-72cjogxz 5434 5 and and CC cord-015369-72cjogxz 5434 6 radiotherapy radiotherapy NN cord-015369-72cjogxz 5434 7 were be VBD cord-015369-72cjogxz 5434 8 analyzed analyze VBN cord-015369-72cjogxz 5434 9 with with IN cord-015369-72cjogxz 5434 10 the the DT cord-015369-72cjogxz 5434 11 above above JJ cord-015369-72cjogxz 5434 12 described describe VBN cord-015369-72cjogxz 5434 13 software software NN cord-015369-72cjogxz 5434 14 . . . cord-015369-72cjogxz 5435 1 All all DT cord-015369-72cjogxz 5435 2 calculations calculation NNS cord-015369-72cjogxz 5435 3 were be VBD cord-015369-72cjogxz 5435 4 transferred transfer VBN cord-015369-72cjogxz 5435 5 to to IN cord-015369-72cjogxz 5435 6 a a DT cord-015369-72cjogxz 5435 7 breast breast NN cord-015369-72cjogxz 5435 8 symmetry symmetry NN cord-015369-72cjogxz 5435 9 index index NN cord-015369-72cjogxz 5435 10 ( ( -LRB- cord-015369-72cjogxz 5435 11 BSI BSI NNP cord-015369-72cjogxz 5435 12 ) ) -RRB- cord-015369-72cjogxz 5435 13 ranging range VBG cord-015369-72cjogxz 5435 14 between between IN cord-015369-72cjogxz 5435 15 0 0 NFP cord-015369-72cjogxz 5435 16 ( ( -LRB- cord-015369-72cjogxz 5435 17 excellent excellent JJ cord-015369-72cjogxz 5435 18 cosm cosm NN cord-015369-72cjogxz 5435 19 - - HYPH cord-015369-72cjogxz 5435 20 esis esis NNP cord-015369-72cjogxz 5435 21 ) ) -RRB- cord-015369-72cjogxz 5435 22 and and CC cord-015369-72cjogxz 5435 23 11 11 CD cord-015369-72cjogxz 5435 24 ( ( -LRB- cord-015369-72cjogxz 5435 25 bad bad JJ cord-015369-72cjogxz 5435 26 cosmesis cosmesis NNP cord-015369-72cjogxz 5435 27 ) ) -RRB- cord-015369-72cjogxz 5435 28 . . . cord-015369-72cjogxz 5436 1 The the DT cord-015369-72cjogxz 5436 2 same same JJ cord-015369-72cjogxz 5436 3 pictures picture NNS cord-015369-72cjogxz 5436 4 were be VBD cord-015369-72cjogxz 5436 5 analyzed analyze VBN cord-015369-72cjogxz 5436 6 by by IN cord-015369-72cjogxz 5436 7 10 10 CD cord-015369-72cjogxz 5436 8 experts expert NNS cord-015369-72cjogxz 5436 9 ( ( -LRB- cord-015369-72cjogxz 5436 10 surgeons surgeon NNS cord-015369-72cjogxz 5436 11 ) ) -RRB- cord-015369-72cjogxz 5436 12 and and CC cord-015369-72cjogxz 5436 13 8 8 CD cord-015369-72cjogxz 5436 14 non non NNS cord-015369-72cjogxz 5436 15 - - NNS cord-015369-72cjogxz 5436 16 experts expert NNS cord-015369-72cjogxz 5436 17 ( ( -LRB- cord-015369-72cjogxz 5436 18 students student NNS cord-015369-72cjogxz 5436 19 ) ) -RRB- cord-015369-72cjogxz 5436 20 using use VBG cord-015369-72cjogxz 5436 21 the the DT cord-015369-72cjogxz 5436 22 Harris Harris NNP cord-015369-72cjogxz 5436 23 scale scale NN cord-015369-72cjogxz 5436 24 ( ( -LRB- cord-015369-72cjogxz 5436 25 subjective subjective JJ cord-015369-72cjogxz 5436 26 score score NN cord-015369-72cjogxz 5436 27 from from IN cord-015369-72cjogxz 5436 28 1 1 CD cord-015369-72cjogxz 5436 29 to to IN cord-015369-72cjogxz 5436 30 4 4 CD cord-015369-72cjogxz 5436 31 ; ; : cord-015369-72cjogxz 5436 32 excellent excellent JJ cord-015369-72cjogxz 5436 33 , , , cord-015369-72cjogxz 5436 34 good good JJ cord-015369-72cjogxz 5436 35 , , , cord-015369-72cjogxz 5436 36 fair fair JJ cord-015369-72cjogxz 5436 37 and and CC cord-015369-72cjogxz 5436 38 poor poor JJ cord-015369-72cjogxz 5436 39 cosmesis cosmesis NNP cord-015369-72cjogxz 5436 40 ) ) -RRB- cord-015369-72cjogxz 5436 41 . . . cord-015369-72cjogxz 5437 1 These these DT cord-015369-72cjogxz 5437 2 subjective subjective JJ cord-015369-72cjogxz 5437 3 scores score NNS cord-015369-72cjogxz 5437 4 were be VBD cord-015369-72cjogxz 5437 5 correlated correlate VBN cord-015369-72cjogxz 5437 6 with with IN cord-015369-72cjogxz 5437 7 the the DT cord-015369-72cjogxz 5437 8 objective objective JJ cord-015369-72cjogxz 5437 9 scores score NNS cord-015369-72cjogxz 5437 10 from from IN cord-015369-72cjogxz 5437 11 the the DT cord-015369-72cjogxz 5437 12 BAT bat NN cord-015369-72cjogxz 5437 13 software software NN cord-015369-72cjogxz 5437 14 using use VBG cord-015369-72cjogxz 5437 15 the the DT cord-015369-72cjogxz 5437 16 Pearson Pearson NNP cord-015369-72cjogxz 5437 17 correlation correlation NN cord-015369-72cjogxz 5437 18 test test NN cord-015369-72cjogxz 5437 19 . . . cord-015369-72cjogxz 5438 1 Results result NNS cord-015369-72cjogxz 5438 2 . . . cord-015369-72cjogxz 5439 1 All all DT cord-015369-72cjogxz 5439 2 subjective subjective JJ cord-015369-72cjogxz 5439 3 scores score NNS cord-015369-72cjogxz 5439 4 significantly significantly RB cord-015369-72cjogxz 5439 5 ( ( -LRB- cord-015369-72cjogxz 5439 6 p p NN cord-015369-72cjogxz 5439 7 < < XX cord-015369-72cjogxz 5439 8 0.05 0.05 CD cord-015369-72cjogxz 5439 9 ) ) -RRB- cord-015369-72cjogxz 5439 10 correlated correlate VBD cord-015369-72cjogxz 5439 11 with with IN cord-015369-72cjogxz 5439 12 the the DT cord-015369-72cjogxz 5439 13 BAT bat NN cord-015369-72cjogxz 5439 14 score score NN cord-015369-72cjogxz 5439 15 with with IN cord-015369-72cjogxz 5439 16 a a DT cord-015369-72cjogxz 5439 17 Pearson Pearson NNP cord-015369-72cjogxz 5439 18 correlation correlation NN cord-015369-72cjogxz 5439 19 coefficient coefficient NN cord-015369-72cjogxz 5439 20 of of IN cord-015369-72cjogxz 5439 21 0.716 0.716 CD cord-015369-72cjogxz 5439 22 ( ( -LRB- cord-015369-72cjogxz 5439 23 non non NNS cord-015369-72cjogxz 5439 24 - - NNS cord-015369-72cjogxz 5439 25 experts expert NNS cord-015369-72cjogxz 5439 26 ) ) -RRB- cord-015369-72cjogxz 5439 27 , , , cord-015369-72cjogxz 5439 28 0.697 0.697 CD cord-015369-72cjogxz 5439 29 ( ( -LRB- cord-015369-72cjogxz 5439 30 experts expert NNS cord-015369-72cjogxz 5439 31 ) ) -RRB- cord-015369-72cjogxz 5439 32 and and CC cord-015369-72cjogxz 5439 33 0.719 0.719 CD cord-015369-72cjogxz 5440 1 ( ( -LRB- cord-015369-72cjogxz 5440 2 overall overall RB cord-015369-72cjogxz 5440 3 ) ) -RRB- cord-015369-72cjogxz 5440 4 . . . cord-015369-72cjogxz 5441 1 Conclusion conclusion NN cord-015369-72cjogxz 5441 2 : : : cord-015369-72cjogxz 5442 1 The the DT cord-015369-72cjogxz 5442 2 technical technical JJ cord-015369-72cjogxz 5442 3 modifications modification NNS cord-015369-72cjogxz 5442 4 of of IN cord-015369-72cjogxz 5442 5 the the DT cord-015369-72cjogxz 5442 6 BAT bat NN cord-015369-72cjogxz 5442 7 - - HYPH cord-015369-72cjogxz 5442 8 software software NN cord-015369-72cjogxz 5442 9 have have VBP cord-015369-72cjogxz 5442 10 lead lead NN cord-015369-72cjogxz 5442 11 to to IN cord-015369-72cjogxz 5442 12 the the DT cord-015369-72cjogxz 5442 13 achievement achievement NN cord-015369-72cjogxz 5442 14 of of IN cord-015369-72cjogxz 5442 15 accurate accurate JJ cord-015369-72cjogxz 5442 16 and and CC cord-015369-72cjogxz 5442 17 reliable reliable JJ cord-015369-72cjogxz 5442 18 results result NNS cord-015369-72cjogxz 5442 19 . . . cord-015369-72cjogxz 5443 1 This this DT cord-015369-72cjogxz 5443 2 qualifies qualify VBZ cord-015369-72cjogxz 5443 3 the the DT cord-015369-72cjogxz 5443 4 use use NN cord-015369-72cjogxz 5443 5 of of IN cord-015369-72cjogxz 5443 6 BAT bat NN cord-015369-72cjogxz 5443 7 in in IN cord-015369-72cjogxz 5443 8 prospective prospective JJ cord-015369-72cjogxz 5443 9 and and CC cord-015369-72cjogxz 5443 10 retrospective retrospective JJ cord-015369-72cjogxz 5443 11 trials trial NNS cord-015369-72cjogxz 5443 12 on on IN cord-015369-72cjogxz 5443 13 breast breast NN cord-015369-72cjogxz 5443 14 cosmesis cosmesis NNP cord-015369-72cjogxz 5443 15 . . . cord-015369-72cjogxz 5444 1 offen offen NNP cord-015369-72cjogxz 5444 2 - - HYPH cord-015369-72cjogxz 5444 3 chirurgische chirurgische NNP cord-015369-72cjogxz 5444 4 Intervention Intervention NNP cord-015369-72cjogxz 5444 5 mit mit NNP cord-015369-72cjogxz 5444 6 hohem hohem NNP cord-015369-72cjogxz 5444 7 Komplikationspotential Komplikationspotential NNP cord-015369-72cjogxz 5444 8 und und IN cord-015369-72cjogxz 5444 9 langem langem VBP cord-015369-72cjogxz 5444 10 Krankenhausaufenthalt Krankenhausaufenthalt NNP cord-015369-72cjogxz 5444 11 zu zu NNP cord-015369-72cjogxz 5444 12 vermeiden vermeiden NNP cord-015369-72cjogxz 5444 13 . . . cord-015369-72cjogxz 5445 1 Local local JJ cord-015369-72cjogxz 5445 2 hyperthermia hyperthermia NN cord-015369-72cjogxz 5445 3 combined combine VBN cord-015369-72cjogxz 5445 4 with with IN cord-015369-72cjogxz 5445 5 external external JJ cord-015369-72cjogxz 5445 6 radiation radiation NN cord-015369-72cjogxz 5445 7 therapy therapy NN cord-015369-72cjogxz 5445 8 as as IN cord-015369-72cjogxz 5445 9 anti anti NNP cord-015369-72cjogxz 5445 10 cancertreatment cancertreatment NN cord-015369-72cjogxz 5445 11 in in IN cord-015369-72cjogxz 5445 12 recurrent recurrent JJ cord-015369-72cjogxz 5445 13 breast breast NN cord-015369-72cjogxz 5445 14 cancer cancer NN cord-015369-72cjogxz 5445 15 Hyperthermia hyperthermia NN cord-015369-72cjogxz 5445 16 combined combine VBN cord-015369-72cjogxz 5445 17 with with IN cord-015369-72cjogxz 5445 18 radiation radiation NN cord-015369-72cjogxz 5445 19 therapy therapy NN cord-015369-72cjogxz 5445 20 has have VBZ cord-015369-72cjogxz 5445 21 been be VBN cord-015369-72cjogxz 5445 22 confirmed confirm VBN cord-015369-72cjogxz 5445 23 in in IN cord-015369-72cjogxz 5445 24 several several JJ cord-015369-72cjogxz 5445 25 randomised randomised JJ cord-015369-72cjogxz 5445 26 studies study NNS cord-015369-72cjogxz 5445 27 to to TO cord-015369-72cjogxz 5445 28 be be VB cord-015369-72cjogxz 5445 29 more more RBR cord-015369-72cjogxz 5445 30 effective effective JJ cord-015369-72cjogxz 5445 31 than than IN cord-015369-72cjogxz 5445 32 radiation radiation NN cord-015369-72cjogxz 5445 33 therapy therapy NN cord-015369-72cjogxz 5445 34 alone alone RB cord-015369-72cjogxz 5445 35 in in IN cord-015369-72cjogxz 5445 36 various various JJ cord-015369-72cjogxz 5445 37 cancers cancer NNS cord-015369-72cjogxz 5445 38 . . . cord-015369-72cjogxz 5446 1 We -PRON- PRP cord-015369-72cjogxz 5446 2 evaluated evaluate VBD cord-015369-72cjogxz 5446 3 the the DT cord-015369-72cjogxz 5446 4 potential potential JJ cord-015369-72cjogxz 5446 5 synergistic synergistic JJ cord-015369-72cjogxz 5446 6 effect effect NN cord-015369-72cjogxz 5446 7 of of IN cord-015369-72cjogxz 5446 8 local local JJ cord-015369-72cjogxz 5446 9 hyperthermia hyperthermia NN cord-015369-72cjogxz 5446 10 and and CC cord-015369-72cjogxz 5446 11 conventional conventional JJ cord-015369-72cjogxz 5446 12 external external JJ cord-015369-72cjogxz 5446 13 beam beam NN cord-015369-72cjogxz 5446 14 radiation radiation NN cord-015369-72cjogxz 5446 15 . . . cord-015369-72cjogxz 5447 1 We -PRON- PRP cord-015369-72cjogxz 5447 2 used use VBD cord-015369-72cjogxz 5447 3 a a DT cord-015369-72cjogxz 5447 4 wave wave NN cord-015369-72cjogxz 5447 5 - - HYPH cord-015369-72cjogxz 5447 6 guide guide NN cord-015369-72cjogxz 5447 7 applicator applicator NN cord-015369-72cjogxz 5447 8 ( ( -LRB- cord-015369-72cjogxz 5447 9 BSD BSD NNP cord-015369-72cjogxz 5447 10 ) ) -RRB- cord-015369-72cjogxz 5447 11 with with IN cord-015369-72cjogxz 5447 12 a a DT cord-015369-72cjogxz 5447 13 typical typical JJ cord-015369-72cjogxz 5447 14 emitting emit VBG cord-015369-72cjogxz 5447 15 diameter diameter NN cord-015369-72cjogxz 5447 16 of of IN cord-015369-72cjogxz 5447 17 15 15 CD cord-015369-72cjogxz 5447 18 cm cm NNS cord-015369-72cjogxz 5447 19 and and CC cord-015369-72cjogxz 5447 20 a a DT cord-015369-72cjogxz 5447 21 frequency frequency NN cord-015369-72cjogxz 5447 22 of of IN cord-015369-72cjogxz 5447 23 150 150 CD cord-015369-72cjogxz 5447 24 - - SYM cord-015369-72cjogxz 5447 25 430 430 CD cord-015369-72cjogxz 5447 26 MHz MHz NNS cord-015369-72cjogxz 5447 27 with with IN cord-015369-72cjogxz 5447 28 a a DT cord-015369-72cjogxz 5447 29 therapeutic therapeutic JJ cord-015369-72cjogxz 5447 30 depth depth NN cord-015369-72cjogxz 5447 31 of of IN cord-015369-72cjogxz 5447 32 3 3 CD cord-015369-72cjogxz 5447 33 cm cm NNS cord-015369-72cjogxz 5447 34 . . . cord-015369-72cjogxz 5448 1 Hyperthermia hyperthermia NN cord-015369-72cjogxz 5448 2 was be VBD cord-015369-72cjogxz 5448 3 performed perform VBN cord-015369-72cjogxz 5448 4 for for IN cord-015369-72cjogxz 5448 5 60 60 CD cord-015369-72cjogxz 5448 6 min min NN cord-015369-72cjogxz 5448 7 for for IN cord-015369-72cjogxz 5448 8 at at IN cord-015369-72cjogxz 5448 9 total total NN cord-015369-72cjogxz 5448 10 of of IN cord-015369-72cjogxz 5448 11 six six CD cord-015369-72cjogxz 5448 12 sessions session NNS cord-015369-72cjogxz 5448 13 , , , cord-015369-72cjogxz 5448 14 twice twice RB cord-015369-72cjogxz 5448 15 weekly weekly NN cord-015369-72cjogxz 5448 16 , , , cord-015369-72cjogxz 5448 17 the the DT cord-015369-72cjogxz 5448 18 temperature temperature NN cord-015369-72cjogxz 5448 19 was be VBD cord-015369-72cjogxz 5448 20 exactly exactly RB cord-015369-72cjogxz 5448 21 calibrated calibrate VBN cord-015369-72cjogxz 5448 22 between between IN cord-015369-72cjogxz 5448 23 40 40 CD cord-015369-72cjogxz 5448 24 and and CC cord-015369-72cjogxz 5448 25 43 43 CD cord-015369-72cjogxz 5448 26 C. c. NN cord-015369-72cjogxz 5449 1 Immediately immediately RB cord-015369-72cjogxz 5449 2 after after IN cord-015369-72cjogxz 5449 3 hyperthermia hyperthermia NN cord-015369-72cjogxz 5449 4 external external JJ cord-015369-72cjogxz 5449 5 radiation radiation NN cord-015369-72cjogxz 5449 6 with with IN cord-015369-72cjogxz 5449 7 60 60 CD cord-015369-72cjogxz 5449 8 Gy Gy NNP cord-015369-72cjogxz 5449 9 was be VBD cord-015369-72cjogxz 5449 10 applied apply VBN cord-015369-72cjogxz 5449 11 in in IN cord-015369-72cjogxz 5449 12 a a DT cord-015369-72cjogxz 5449 13 daily daily JJ cord-015369-72cjogxz 5449 14 fraction fraction NN cord-015369-72cjogxz 5449 15 of of IN cord-015369-72cjogxz 5449 16 1.5 1.5 CD cord-015369-72cjogxz 5449 17 Gy Gy NNP cord-015369-72cjogxz 5449 18 . . . cord-015369-72cjogxz 5450 1 No no DT cord-015369-72cjogxz 5450 2 major major JJ cord-015369-72cjogxz 5450 3 side side NN cord-015369-72cjogxz 5450 4 effects effect NNS cord-015369-72cjogxz 5450 5 were be VBD cord-015369-72cjogxz 5450 6 observed observe VBN cord-015369-72cjogxz 5450 7 during during IN cord-015369-72cjogxz 5450 8 hyperthermia hyperthermia NN cord-015369-72cjogxz 5450 9 . . . cord-015369-72cjogxz 5451 1 12 12 CD cord-015369-72cjogxz 5451 2 patients patient NNS cord-015369-72cjogxz 5451 3 were be VBD cord-015369-72cjogxz 5451 4 treated treat VBN cord-015369-72cjogxz 5451 5 and and CC cord-015369-72cjogxz 5451 6 followed follow VBN cord-015369-72cjogxz 5451 7 for for IN cord-015369-72cjogxz 5451 8 during during IN cord-015369-72cjogxz 5451 9 2 2 CD cord-015369-72cjogxz 5451 10 - - SYM cord-015369-72cjogxz 5451 11 12 12 CD cord-015369-72cjogxz 5451 12 months month NNS cord-015369-72cjogxz 5451 13 . . . cord-015369-72cjogxz 5452 1 Ten ten CD cord-015369-72cjogxz 5452 2 of of IN cord-015369-72cjogxz 5452 3 the the DT cord-015369-72cjogxz 5452 4 tumours tumour NNS cord-015369-72cjogxz 5452 5 responded respond VBD cord-015369-72cjogxz 5452 6 to to IN cord-015369-72cjogxz 5452 7 the the DT cord-015369-72cjogxz 5452 8 treatment treatment NN cord-015369-72cjogxz 5452 9 ( ( -LRB- cord-015369-72cjogxz 5452 10 3 3 CD cord-015369-72cjogxz 5452 11 CR cr NN cord-015369-72cjogxz 5452 12 , , , cord-015369-72cjogxz 5452 13 7PR 7pr CD cord-015369-72cjogxz 5452 14 ) ) -RRB- cord-015369-72cjogxz 5452 15 , , , cord-015369-72cjogxz 5452 16 two two CD cord-015369-72cjogxz 5452 17 patients patient NNS cord-015369-72cjogxz 5452 18 died die VBD cord-015369-72cjogxz 5452 19 of of IN cord-015369-72cjogxz 5452 20 distant distant JJ cord-015369-72cjogxz 5452 21 metastases metastasis NNS cord-015369-72cjogxz 5452 22 within within IN cord-015369-72cjogxz 5452 23 one one CD cord-015369-72cjogxz 5452 24 year year NN cord-015369-72cjogxz 5452 25 . . . cord-015369-72cjogxz 5453 1 Local local JJ cord-015369-72cjogxz 5453 2 hyperthermia hyperthermia NN cord-015369-72cjogxz 5453 3 combined combine VBN cord-015369-72cjogxz 5453 4 with with IN cord-015369-72cjogxz 5453 5 conventional conventional JJ cord-015369-72cjogxz 5453 6 radiation radiation NN cord-015369-72cjogxz 5453 7 therapy therapy NN cord-015369-72cjogxz 5453 8 may may MD cord-015369-72cjogxz 5453 9 be be VB cord-015369-72cjogxz 5453 10 useful useful JJ cord-015369-72cjogxz 5453 11 tool tool NN cord-015369-72cjogxz 5453 12 to to TO cord-015369-72cjogxz 5453 13 promote promote VB cord-015369-72cjogxz 5453 14 tumor tumor NN cord-015369-72cjogxz 5453 15 regression regression NN cord-015369-72cjogxz 5453 16 and and CC cord-015369-72cjogxz 5453 17 the the DT cord-015369-72cjogxz 5453 18 local local JJ cord-015369-72cjogxz 5453 19 recurrence recurrence NN cord-015369-72cjogxz 5453 20 - - HYPH cord-015369-72cjogxz 5453 21 free free JJ cord-015369-72cjogxz 5453 22 survival survival NN cord-015369-72cjogxz 5453 23 in in IN cord-015369-72cjogxz 5453 24 cases case NNS cord-015369-72cjogxz 5453 25 of of IN cord-015369-72cjogxz 5453 26 recurrance recurrance NN cord-015369-72cjogxz 5453 27 breast breast NN cord-015369-72cjogxz 5453 28 cancer cancer NN cord-015369-72cjogxz 5453 29 . . . cord-015369-72cjogxz 5454 1 We -PRON- PRP cord-015369-72cjogxz 5454 2 conclude conclude VBP cord-015369-72cjogxz 5454 3 that that IN cord-015369-72cjogxz 5454 4 hyperthermia hyperthermia NN cord-015369-72cjogxz 5454 5 and and CC cord-015369-72cjogxz 5454 6 radiation radiation NN cord-015369-72cjogxz 5454 7 therapy therapy NN cord-015369-72cjogxz 5454 8 is be VBZ cord-015369-72cjogxz 5454 9 effective effective JJ cord-015369-72cjogxz 5454 10 in in IN cord-015369-72cjogxz 5454 11 treatment treatment NN cord-015369-72cjogxz 5454 12 breast breast NN cord-015369-72cjogxz 5454 13 cancer cancer NN cord-015369-72cjogxz 5454 14 treatment treatment NN cord-015369-72cjogxz 5454 15 and and CC cord-015369-72cjogxz 5454 16 should should MD cord-015369-72cjogxz 5454 17 be be VB cord-015369-72cjogxz 5454 18 used use VBN cord-015369-72cjogxz 5454 19 in in IN cord-015369-72cjogxz 5454 20 selected select VBN cord-015369-72cjogxz 5454 21 cancer cancer NN cord-015369-72cjogxz 5454 22 patients patient NNS cord-015369-72cjogxz 5454 23 . . . cord-015369-72cjogxz 5455 1 Sentinel Sentinel NNP cord-015369-72cjogxz 5455 2 - - HYPH cord-015369-72cjogxz 5455 3 Node Node NNP cord-015369-72cjogxz 5455 4 biopsy biopsy NN cord-015369-72cjogxz 5455 5 und und IN cord-015369-72cjogxz 5456 1 Lymphatic Lymphatic NNP cord-015369-72cjogxz 5456 2 Mapping Mapping NNP cord-015369-72cjogxz 5456 3 von von NNP cord-015369-72cjogxz 5456 4 malignen malignen NNP cord-015369-72cjogxz 5457 1 Tumoren Tumoren NNP cord-015369-72cjogxz 5457 2 mittels mittel NNS cord-015369-72cjogxz 5457 3 eines eines NNP cord-015369-72cjogxz 5457 4 Fluoreszenz Fluoreszenz NNP cord-015369-72cjogxz 5457 5 - - HYPH cord-015369-72cjogxz 5457 6 Tracers Tracers NNP cord-015369-72cjogxz 5457 7 ( ( -LRB- cord-015369-72cjogxz 5457 8 ICG ICG NNP cord-015369-72cjogxz 5457 9 ) ) -RRB- cord-015369-72cjogxz 5457 10 _SP cord-015369-72cjogxz 5458 1 The the DT cord-015369-72cjogxz 5458 2 potential potential NN cord-015369-72cjogxz 5458 3 of of IN cord-015369-72cjogxz 5458 4 plasma plasma NN cord-015369-72cjogxz 5458 5 proteomics proteomic NNS cord-015369-72cjogxz 5458 6 in in IN cord-015369-72cjogxz 5458 7 predicting predict VBG cord-015369-72cjogxz 5458 8 response response NN cord-015369-72cjogxz 5458 9 to to IN cord-015369-72cjogxz 5458 10 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 5458 11 chemotherapy chemotherapy NN cord-015369-72cjogxz 5458 12 in in IN cord-015369-72cjogxz 5458 13 breast breast NN cord-015369-72cjogxz 5458 14 cancer cancer NN cord-015369-72cjogxz 5458 15 patients patient NNS cord-015369-72cjogxz 5458 16 using use VBG cord-015369-72cjogxz 5458 17 2D 2d JJ cord-015369-72cjogxz 5458 18 - - HYPH cord-015369-72cjogxz 5458 19 DIGE DIGE NNP cord-015369-72cjogxz 5458 20 Resistance Resistance NNP cord-015369-72cjogxz 5458 21 to to IN cord-015369-72cjogxz 5458 22 chemotherapy chemotherapy NN cord-015369-72cjogxz 5458 23 is be VBZ cord-015369-72cjogxz 5458 24 still still RB cord-015369-72cjogxz 5458 25 a a DT cord-015369-72cjogxz 5458 26 major major JJ cord-015369-72cjogxz 5458 27 problem problem NN cord-015369-72cjogxz 5458 28 in in IN cord-015369-72cjogxz 5458 29 oncology oncology NN cord-015369-72cjogxz 5458 30 . . . cord-015369-72cjogxz 5459 1 Especially especially RB cord-015369-72cjogxz 5459 2 for for IN cord-015369-72cjogxz 5459 3 hormone hormone NN cord-015369-72cjogxz 5459 4 receptor receptor NN cord-015369-72cjogxz 5459 5 negative negative JJ cord-015369-72cjogxz 5459 6 tumours tumour NNS cord-015369-72cjogxz 5459 7 there there EX cord-015369-72cjogxz 5459 8 are be VBP cord-015369-72cjogxz 5459 9 no no DT cord-015369-72cjogxz 5459 10 biomarkers biomarker NNS cord-015369-72cjogxz 5459 11 available available JJ cord-015369-72cjogxz 5459 12 which which WDT cord-015369-72cjogxz 5459 13 identify identify VBP cord-015369-72cjogxz 5459 14 patients patient NNS cord-015369-72cjogxz 5459 15 who who WP cord-015369-72cjogxz 5459 16 will will MD cord-015369-72cjogxz 5459 17 not not RB cord-015369-72cjogxz 5459 18 profit profit VB cord-015369-72cjogxz 5459 19 from from IN cord-015369-72cjogxz 5459 20 treatment treatment NN cord-015369-72cjogxz 5459 21 . . . cord-015369-72cjogxz 5460 1 Such such JJ cord-015369-72cjogxz 5460 2 a a DT cord-015369-72cjogxz 5460 3 selection selection NN cord-015369-72cjogxz 5460 4 would would MD cord-015369-72cjogxz 5460 5 allow allow VB cord-015369-72cjogxz 5460 6 for for IN cord-015369-72cjogxz 5460 7 a a DT cord-015369-72cjogxz 5460 8 switch switch NN cord-015369-72cjogxz 5460 9 to to IN cord-015369-72cjogxz 5460 10 another another DT cord-015369-72cjogxz 5460 11 more more RBR cord-015369-72cjogxz 5460 12 effective effective JJ cord-015369-72cjogxz 5460 13 chemotherapeutic chemotherapeutic JJ cord-015369-72cjogxz 5460 14 regimen regimen NN cord-015369-72cjogxz 5460 15 for for IN cord-015369-72cjogxz 5460 16 these these DT cord-015369-72cjogxz 5460 17 patients patient NNS cord-015369-72cjogxz 5460 18 . . . cord-015369-72cjogxz 5461 1 Chemotherapy chemotherapy NN cord-015369-72cjogxz 5461 2 not not RB cord-015369-72cjogxz 5461 3 only only RB cord-015369-72cjogxz 5461 4 leads lead VBZ cord-015369-72cjogxz 5461 5 to to IN cord-015369-72cjogxz 5461 6 the the DT cord-015369-72cjogxz 5461 7 destruction destruction NN cord-015369-72cjogxz 5461 8 of of IN cord-015369-72cjogxz 5461 9 tumour tumour NN cord-015369-72cjogxz 5461 10 cells cell NNS cord-015369-72cjogxz 5461 11 , , , cord-015369-72cjogxz 5461 12 but but CC cord-015369-72cjogxz 5461 13 also also RB cord-015369-72cjogxz 5461 14 affects affect VBZ cord-015369-72cjogxz 5461 15 actively actively RB cord-015369-72cjogxz 5461 16 proliferating proliferate VBG cord-015369-72cjogxz 5461 17 healthy healthy JJ cord-015369-72cjogxz 5461 18 tissues tissue NNS cord-015369-72cjogxz 5461 19 as as RB cord-015369-72cjogxz 5461 20 well well RB cord-015369-72cjogxz 5461 21 as as IN cord-015369-72cjogxz 5461 22 the the DT cord-015369-72cjogxz 5461 23 immune immune JJ cord-015369-72cjogxz 5461 24 system system NN cord-015369-72cjogxz 5461 25 . . . cord-015369-72cjogxz 5462 1 As as IN cord-015369-72cjogxz 5462 2 shown show VBN cord-015369-72cjogxz 5462 3 in in IN cord-015369-72cjogxz 5462 4 another another DT cord-015369-72cjogxz 5462 5 abstract abstract NN cord-015369-72cjogxz 5462 6 of of IN cord-015369-72cjogxz 5462 7 our -PRON- PRP$ cord-015369-72cjogxz 5462 8 group group NN cord-015369-72cjogxz 5462 9 , , , cord-015369-72cjogxz 5462 10 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 5462 11 chemotherapy chemotherapy NN cord-015369-72cjogxz 5462 12 of of IN cord-015369-72cjogxz 5462 13 breast breast NN cord-015369-72cjogxz 5462 14 cancer cancer NN cord-015369-72cjogxz 5462 15 patients patient NNS cord-015369-72cjogxz 5462 16 with with IN cord-015369-72cjogxz 5462 17 epirubicin epirubicin NNS cord-015369-72cjogxz 5462 18 and and CC cord-015369-72cjogxz 5462 19 docetaxel docetaxel JJ cord-015369-72cjogxz 5462 20 leads lead VBZ cord-015369-72cjogxz 5462 21 to to IN cord-015369-72cjogxz 5462 22 expression expression NN cord-015369-72cjogxz 5462 23 changes change NNS cord-015369-72cjogxz 5462 24 of of IN cord-015369-72cjogxz 5462 25 distinct distinct JJ cord-015369-72cjogxz 5462 26 plasma plasma NN cord-015369-72cjogxz 5462 27 proteins protein NNS cord-015369-72cjogxz 5462 28 within within IN cord-015369-72cjogxz 5462 29 2 2 CD cord-015369-72cjogxz 5462 30 days day NNS cord-015369-72cjogxz 5462 31 . . . cord-015369-72cjogxz 5463 1 Based base VBN cord-015369-72cjogxz 5463 2 on on IN cord-015369-72cjogxz 5463 3 these these DT cord-015369-72cjogxz 5463 4 results result NNS cord-015369-72cjogxz 5463 5 , , , cord-015369-72cjogxz 5463 6 we -PRON- PRP cord-015369-72cjogxz 5463 7 investigated investigate VBD cord-015369-72cjogxz 5463 8 whether whether IN cord-015369-72cjogxz 5463 9 such such JJ cord-015369-72cjogxz 5463 10 changes change NNS cord-015369-72cjogxz 5463 11 can can MD cord-015369-72cjogxz 5463 12 be be VB cord-015369-72cjogxz 5463 13 correlated correlate VBN cord-015369-72cjogxz 5463 14 with with IN cord-015369-72cjogxz 5463 15 the the DT cord-015369-72cjogxz 5463 16 final final JJ cord-015369-72cjogxz 5463 17 response response NN cord-015369-72cjogxz 5463 18 to to IN cord-015369-72cjogxz 5463 19 chemotherapeutic chemotherapeutic JJ cord-015369-72cjogxz 5463 20 treatment treatment NN cord-015369-72cjogxz 5463 21 assessed assess VBN cord-015369-72cjogxz 5463 22 12 12 CD cord-015369-72cjogxz 5463 23 weeks week NNS cord-015369-72cjogxz 5463 24 later later RB cord-015369-72cjogxz 5463 25 . . . cord-015369-72cjogxz 5464 1 Therefore therefore RB cord-015369-72cjogxz 5464 2 , , , cord-015369-72cjogxz 5464 3 plasma plasma NN cord-015369-72cjogxz 5464 4 was be VBD cord-015369-72cjogxz 5464 5 prepared prepare VBN cord-015369-72cjogxz 5464 6 from from IN cord-015369-72cjogxz 5464 7 23 23 CD cord-015369-72cjogxz 5464 8 breast breast NN cord-015369-72cjogxz 5464 9 cancer cancer NN cord-015369-72cjogxz 5464 10 patients patient NNS cord-015369-72cjogxz 5464 11 before before IN cord-015369-72cjogxz 5464 12 and and CC cord-015369-72cjogxz 5464 13 2 2 CD cord-015369-72cjogxz 5464 14 - - SYM cord-015369-72cjogxz 5464 15 4 4 CD cord-015369-72cjogxz 5464 16 days day NNS cord-015369-72cjogxz 5464 17 after after IN cord-015369-72cjogxz 5464 18 receiving receive VBG cord-015369-72cjogxz 5464 19 the the DT cord-015369-72cjogxz 5464 20 first first JJ cord-015369-72cjogxz 5464 21 course course NN cord-015369-72cjogxz 5464 22 of of IN cord-015369-72cjogxz 5464 23 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 5464 24 chemotherapy chemotherapy NN cord-015369-72cjogxz 5464 25 . . . cord-015369-72cjogxz 5465 1 After after IN cord-015369-72cjogxz 5465 2 the the DT cord-015369-72cjogxz 5465 3 removal removal NN cord-015369-72cjogxz 5465 4 of of IN cord-015369-72cjogxz 5465 5 12 12 CD cord-015369-72cjogxz 5465 6 major major JJ cord-015369-72cjogxz 5465 7 abundant abundant JJ cord-015369-72cjogxz 5465 8 plasma plasma NN cord-015369-72cjogxz 5465 9 proteins protein NNS cord-015369-72cjogxz 5465 10 by by IN cord-015369-72cjogxz 5465 11 affinity affinity NN cord-015369-72cjogxz 5465 12 chromatography chromatography NN cord-015369-72cjogxz 5465 13 , , , cord-015369-72cjogxz 5465 14 proteomic proteomic JJ cord-015369-72cjogxz 5465 15 analysis analysis NN cord-015369-72cjogxz 5465 16 was be VBD cord-015369-72cjogxz 5465 17 performed perform VBN cord-015369-72cjogxz 5465 18 using use VBG cord-015369-72cjogxz 5465 19 2D 2d NN cord-015369-72cjogxz 5465 20 - - HYPH cord-015369-72cjogxz 5465 21 DIGE DIGE NNP cord-015369-72cjogxz 5465 22 . . . cord-015369-72cjogxz 5466 1 Eight eight CD cord-015369-72cjogxz 5466 2 out out IN cord-015369-72cjogxz 5466 3 of of IN cord-015369-72cjogxz 5466 4 577 577 CD cord-015369-72cjogxz 5466 5 protein protein NN cord-015369-72cjogxz 5466 6 spots spot NNS cord-015369-72cjogxz 5466 7 showed show VBD cord-015369-72cjogxz 5466 8 a a DT cord-015369-72cjogxz 5466 9 higher high JJR cord-015369-72cjogxz 5466 10 chemotherapy chemotherapy NN cord-015369-72cjogxz 5466 11 - - HYPH cord-015369-72cjogxz 5466 12 induced induce VBN cord-015369-72cjogxz 5466 13 increase increase NN cord-015369-72cjogxz 5466 14 in in IN cord-015369-72cjogxz 5466 15 expression expression NN cord-015369-72cjogxz 5466 16 ( ( -LRB- cord-015369-72cjogxz 5466 17 p p NN cord-015369-72cjogxz 5466 18 < < XX cord-015369-72cjogxz 5466 19 0.05 0.05 CD cord-015369-72cjogxz 5466 20 ) ) -RRB- cord-015369-72cjogxz 5466 21 in in IN cord-015369-72cjogxz 5466 22 responders responder NNS cord-015369-72cjogxz 5466 23 ( ( -LRB- cord-015369-72cjogxz 5466 24 n n CC cord-015369-72cjogxz 5466 25 ¼ ¼ NNP cord-015369-72cjogxz 5466 26 16 16 CD cord-015369-72cjogxz 5466 27 ) ) -RRB- cord-015369-72cjogxz 5466 28 compared compare VBN cord-015369-72cjogxz 5466 29 to to IN cord-015369-72cjogxz 5466 30 non non JJ cord-015369-72cjogxz 5466 31 - - NNS cord-015369-72cjogxz 5466 32 responders responder NNS cord-015369-72cjogxz 5466 33 ( ( -LRB- cord-015369-72cjogxz 5466 34 n n CC cord-015369-72cjogxz 5466 35 ¼ ¼ NNP cord-015369-72cjogxz 5466 36 7 7 CD cord-015369-72cjogxz 5466 37 ) ) -RRB- cord-015369-72cjogxz 5466 38 , , , cord-015369-72cjogxz 5466 39 whereas whereas IN cord-015369-72cjogxz 5466 40 one one CD cord-015369-72cjogxz 5466 41 protein protein NN cord-015369-72cjogxz 5466 42 behaved behave VBD cord-015369-72cjogxz 5466 43 vice vice NN cord-015369-72cjogxz 5466 44 versa versa RB cord-015369-72cjogxz 5466 45 . . . cord-015369-72cjogxz 5467 1 These these DT cord-015369-72cjogxz 5467 2 proteins protein NNS cord-015369-72cjogxz 5467 3 might may MD cord-015369-72cjogxz 5467 4 be be VB cord-015369-72cjogxz 5467 5 useful useful JJ cord-015369-72cjogxz 5467 6 in in IN cord-015369-72cjogxz 5467 7 future future NN cord-015369-72cjogxz 5467 8 for for IN cord-015369-72cjogxz 5467 9 an an DT cord-015369-72cjogxz 5467 10 early early JJ cord-015369-72cjogxz 5467 11 identification identification NN cord-015369-72cjogxz 5467 12 of of IN cord-015369-72cjogxz 5467 13 those those DT cord-015369-72cjogxz 5467 14 patients patient NNS cord-015369-72cjogxz 5467 15 who who WP cord-015369-72cjogxz 5467 16 will will MD cord-015369-72cjogxz 5467 17 not not RB cord-015369-72cjogxz 5467 18 benefit benefit VB cord-015369-72cjogxz 5467 19 from from IN cord-015369-72cjogxz 5467 20 this this DT cord-015369-72cjogxz 5467 21 kind kind NN cord-015369-72cjogxz 5467 22 of of IN cord-015369-72cjogxz 5467 23 treatment treatment NN cord-015369-72cjogxz 5467 24 . . . cord-015369-72cjogxz 5468 1 For for IN cord-015369-72cjogxz 5468 2 further further JJ cord-015369-72cjogxz 5468 3 investigation investigation NN cord-015369-72cjogxz 5468 4 these these DT cord-015369-72cjogxz 5468 5 protein protein NN cord-015369-72cjogxz 5468 6 spots spot NNS cord-015369-72cjogxz 5468 7 will will MD cord-015369-72cjogxz 5468 8 be be VB cord-015369-72cjogxz 5468 9 identified identify VBN cord-015369-72cjogxz 5468 10 by by IN cord-015369-72cjogxz 5468 11 mass mass NN cord-015369-72cjogxz 5468 12 spectrometry spectrometry NN cord-015369-72cjogxz 5468 13 and and CC cord-015369-72cjogxz 5468 14 for for IN cord-015369-72cjogxz 5468 15 verification verification NN cord-015369-72cjogxz 5468 16 of of IN cord-015369-72cjogxz 5468 17 the the DT cord-015369-72cjogxz 5468 18 2D 2d JJ cord-015369-72cjogxz 5468 19 - - HYPH cord-015369-72cjogxz 5468 20 DIGE dige NN cord-015369-72cjogxz 5468 21 results result NNS cord-015369-72cjogxz 5468 22 quantitative quantitative JJ cord-015369-72cjogxz 5468 23 1D 1d CD cord-015369-72cjogxz 5468 24 Western western JJ cord-015369-72cjogxz 5468 25 blots blot NNS cord-015369-72cjogxz 5468 26 are be VBP cord-015369-72cjogxz 5468 27 planned plan VBN cord-015369-72cjogxz 5468 28 . . . cord-015369-72cjogxz 5469 1 Background background NN cord-015369-72cjogxz 5469 2 . . . cord-015369-72cjogxz 5470 1 DeMeester DeMeester NNP cord-015369-72cjogxz 5470 2 's 's POS cord-015369-72cjogxz 5470 3 composite composite JJ cord-015369-72cjogxz 5470 4 score score NN cord-015369-72cjogxz 5470 5 ( ( -LRB- cord-015369-72cjogxz 5470 6 CS CS NNP cord-015369-72cjogxz 5470 7 ) ) -RRB- cord-015369-72cjogxz 5470 8 is be VBZ cord-015369-72cjogxz 5470 9 a a DT cord-015369-72cjogxz 5470 10 convenient convenient JJ cord-015369-72cjogxz 5470 11 parameter parameter NN cord-015369-72cjogxz 5470 12 to to TO cord-015369-72cjogxz 5470 13 assess assess VB cord-015369-72cjogxz 5470 14 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 5470 15 reflux reflux NN cord-015369-72cjogxz 5470 16 activity activity NN cord-015369-72cjogxz 5470 17 by by IN cord-015369-72cjogxz 5470 18 24 24 CD cord-015369-72cjogxz 5470 19 h h NN cord-015369-72cjogxz 5470 20 pH ph NN cord-015369-72cjogxz 5470 21 - - HYPH cord-015369-72cjogxz 5470 22 monitoring monitoring NN cord-015369-72cjogxz 5470 23 . . . cord-015369-72cjogxz 5471 1 Ingestion ingestion NN cord-015369-72cjogxz 5471 2 of of IN cord-015369-72cjogxz 5471 3 acidic acidic JJ cord-015369-72cjogxz 5471 4 foods food NNS cord-015369-72cjogxz 5471 5 has have VBZ cord-015369-72cjogxz 5471 6 been be VBN cord-015369-72cjogxz 5471 7 reported report VBN cord-015369-72cjogxz 5471 8 to to TO cord-015369-72cjogxz 5471 9 compromise compromise VB cord-015369-72cjogxz 5471 10 the the DT cord-015369-72cjogxz 5471 11 reliability reliability NN cord-015369-72cjogxz 5471 12 of of IN cord-015369-72cjogxz 5471 13 this this DT cord-015369-72cjogxz 5471 14 parameter parameter NN cord-015369-72cjogxz 5471 15 . . . cord-015369-72cjogxz 5472 1 Aim aim VB cord-015369-72cjogxz 5472 2 of of IN cord-015369-72cjogxz 5472 3 this this DT cord-015369-72cjogxz 5472 4 study study NN cord-015369-72cjogxz 5472 5 was be VBD cord-015369-72cjogxz 5472 6 to to TO cord-015369-72cjogxz 5472 7 evaluate evaluate VB cord-015369-72cjogxz 5472 8 the the DT cord-015369-72cjogxz 5472 9 impact impact NN cord-015369-72cjogxz 5472 10 of of IN cord-015369-72cjogxz 5472 11 meals meal NNS cord-015369-72cjogxz 5472 12 on on IN cord-015369-72cjogxz 5472 13 CS CS NNP cord-015369-72cjogxz 5472 14 . . . cord-015369-72cjogxz 5472 15 Methods method NNS cord-015369-72cjogxz 5472 16 . . . cord-015369-72cjogxz 5473 1 In in IN cord-015369-72cjogxz 5473 2 a a DT cord-015369-72cjogxz 5473 3 100 100 CD cord-015369-72cjogxz 5473 4 consecutive consecutive JJ cord-015369-72cjogxz 5473 5 pH ph NN cord-015369-72cjogxz 5473 6 - - HYPH cord-015369-72cjogxz 5473 7 studies study NNS cord-015369-72cjogxz 5473 8 exclusion exclusion NN cord-015369-72cjogxz 5473 9 of of IN cord-015369-72cjogxz 5473 10 meals meal NNS cord-015369-72cjogxz 5473 11 resulted result VBD cord-015369-72cjogxz 5473 12 in in IN cord-015369-72cjogxz 5473 13 CS CS NNP cord-015369-72cjogxz 5473 14 values value NNS cord-015369-72cjogxz 5473 15 3.3 3.3 CD cord-015369-72cjogxz 5473 16 higher high JJR cord-015369-72cjogxz 5473 17 to to IN cord-015369-72cjogxz 5473 18 3.7 3.7 CD cord-015369-72cjogxz 5473 19 lower low JJR cord-015369-72cjogxz 5473 20 than than IN cord-015369-72cjogxz 5473 21 including include VBG cord-015369-72cjogxz 5473 22 meals meal NNS cord-015369-72cjogxz 5473 23 . . . cord-015369-72cjogxz 5474 1 The the DT cord-015369-72cjogxz 5474 2 range range NN cord-015369-72cjogxz 5474 3 of of IN cord-015369-72cjogxz 5474 4 differences difference NNS cord-015369-72cjogxz 5474 5 ( ( -LRB- cord-015369-72cjogxz 5474 6 CS CS NNP cord-015369-72cjogxz 5474 7 11.0 11.0 CD cord-015369-72cjogxz 5474 8 - - HYPH cord-015369-72cjogxz 5474 9 18.0 18.0 CD cord-015369-72cjogxz 5474 10 ) ) -RRB- cord-015369-72cjogxz 5474 11 was be VBD cord-015369-72cjogxz 5474 12 used use VBN cord-015369-72cjogxz 5474 13 as as IN cord-015369-72cjogxz 5474 14 a a DT cord-015369-72cjogxz 5474 15 reference reference NN cord-015369-72cjogxz 5474 16 for for IN cord-015369-72cjogxz 5474 17 selection selection NN cord-015369-72cjogxz 5474 18 of of IN cord-015369-72cjogxz 5474 19 risk risk NN cord-015369-72cjogxz 5474 20 group group NN cord-015369-72cjogxz 5474 21 to to TO cord-015369-72cjogxz 5474 22 cross cross VB cord-015369-72cjogxz 5474 23 the the DT cord-015369-72cjogxz 5474 24 cut cut VB cord-015369-72cjogxz 5474 25 - - HYPH cord-015369-72cjogxz 5474 26 off off RP cord-015369-72cjogxz 5474 27 value value NN cord-015369-72cjogxz 5474 28 when when WRB cord-015369-72cjogxz 5474 29 analyzed analyze VBN cord-015369-72cjogxz 5474 30 without without IN cord-015369-72cjogxz 5474 31 meals meal NNS cord-015369-72cjogxz 5474 32 . . . cord-015369-72cjogxz 5475 1 Results result NNS cord-015369-72cjogxz 5475 2 . . . cord-015369-72cjogxz 5476 1 79 79 CD cord-015369-72cjogxz 5476 2 of of IN cord-015369-72cjogxz 5476 3 515 515 CD cord-015369-72cjogxz 5476 4 patients patient NNS cord-015369-72cjogxz 5476 5 with with IN cord-015369-72cjogxz 5476 6 clinical clinical JJ cord-015369-72cjogxz 5476 7 signs sign NNS cord-015369-72cjogxz 5476 8 of of IN cord-015369-72cjogxz 5476 9 GERD GERD NNP cord-015369-72cjogxz 5476 10 who who WP cord-015369-72cjogxz 5476 11 underwent undergo VBD cord-015369-72cjogxz 5476 12 pH pH NNP cord-015369-72cjogxz 5476 13 monitoring monitoring NN cord-015369-72cjogxz 5476 14 during during IN cord-015369-72cjogxz 5476 15 one one CD cord-015369-72cjogxz 5476 16 year year NN cord-015369-72cjogxz 5476 17 , , , cord-015369-72cjogxz 5476 18 had have VBD cord-015369-72cjogxz 5476 19 a a DT cord-015369-72cjogxz 5476 20 CS CS NNP cord-015369-72cjogxz 5476 21 11.0 11.0 CD cord-015369-72cjogxz 5476 22 - - HYPH cord-015369-72cjogxz 5476 23 18.0 18.0 CD cord-015369-72cjogxz 5476 24 and and CC cord-015369-72cjogxz 5476 25 their -PRON- PRP$ cord-015369-72cjogxz 5476 26 studies study NNS cord-015369-72cjogxz 5476 27 were be VBD cord-015369-72cjogxz 5476 28 reanalyzed reanalyze VBN cord-015369-72cjogxz 5476 29 . . . cord-015369-72cjogxz 5477 1 Median median JJ cord-015369-72cjogxz 5477 2 CS CS NNP cord-015369-72cjogxz 5477 3 was be VBD cord-015369-72cjogxz 5477 4 14.7 14.7 CD cord-015369-72cjogxz 5477 5 ( ( -LRB- cord-015369-72cjogxz 5477 6 12.5 12.5 CD cord-015369-72cjogxz 5477 7 - - HYPH cord-015369-72cjogxz 5477 8 16.5 16.5 CD cord-015369-72cjogxz 5477 9 ) ) -RRB- cord-015369-72cjogxz 5477 10 including include VBG cord-015369-72cjogxz 5477 11 and and CC cord-015369-72cjogxz 5477 12 14.5 14.5 CD cord-015369-72cjogxz 5477 13 ( ( -LRB- cord-015369-72cjogxz 5477 14 12.4 12.4 CD cord-015369-72cjogxz 5477 15 - - SYM cord-015369-72cjogxz 5477 16 16.6 16.6 CD cord-015369-72cjogxz 5477 17 ) ) -RRB- cord-015369-72cjogxz 5477 18 excluding exclude VBG cord-015369-72cjogxz 5477 19 meals meal NNS cord-015369-72cjogxz 5477 20 . . . cord-015369-72cjogxz 5478 1 In in IN cord-015369-72cjogxz 5478 2 eleven eleven CD cord-015369-72cjogxz 5478 3 patients patient NNS cord-015369-72cjogxz 5478 4 the the DT cord-015369-72cjogxz 5478 5 cut cut NN cord-015369-72cjogxz 5478 6 - - HYPH cord-015369-72cjogxz 5478 7 off off NN cord-015369-72cjogxz 5478 8 was be VBD cord-015369-72cjogxz 5478 9 crossed cross VBN cord-015369-72cjogxz 5478 10 depending depend VBG cord-015369-72cjogxz 5478 11 on on IN cord-015369-72cjogxz 5478 12 analysis analysis NN cord-015369-72cjogxz 5478 13 type type NN cord-015369-72cjogxz 5478 14 . . . cord-015369-72cjogxz 5479 1 Multivariate multivariate JJ cord-015369-72cjogxz 5479 2 logistic logistic JJ cord-015369-72cjogxz 5479 3 regression regression NN cord-015369-72cjogxz 5479 4 including include VBG cord-015369-72cjogxz 5479 5 gender gender NN cord-015369-72cjogxz 5479 6 , , , cord-015369-72cjogxz 5479 7 oesophageal oesophageal JJ cord-015369-72cjogxz 5479 8 motility motility NN cord-015369-72cjogxz 5479 9 , , , cord-015369-72cjogxz 5479 10 recumbent recumbent JJ cord-015369-72cjogxz 5479 11 periods period NNS cord-015369-72cjogxz 5479 12 , , , cord-015369-72cjogxz 5479 13 meals meal NNS cord-015369-72cjogxz 5479 14 ' ' POS cord-015369-72cjogxz 5479 15 duration duration NN cord-015369-72cjogxz 5479 16 and and CC cord-015369-72cjogxz 5479 17 number number NN cord-015369-72cjogxz 5479 18 of of IN cord-015369-72cjogxz 5479 19 acidic acidic JJ cord-015369-72cjogxz 5479 20 foods food NNS cord-015369-72cjogxz 5479 21 / / SYM cord-015369-72cjogxz 5479 22 beverages beverage NNS cord-015369-72cjogxz 5479 23 were be VBD cord-015369-72cjogxz 5479 24 performed perform VBN cord-015369-72cjogxz 5479 25 to to TO cord-015369-72cjogxz 5479 26 identify identify VB cord-015369-72cjogxz 5479 27 risk risk NN cord-015369-72cjogxz 5479 28 factors factor NNS cord-015369-72cjogxz 5479 29 for for IN cord-015369-72cjogxz 5479 30 changing change VBG cord-015369-72cjogxz 5479 31 CS CS NNP cord-015369-72cjogxz 5479 32 interpretation interpretation NN cord-015369-72cjogxz 5479 33 . . . cord-015369-72cjogxz 5480 1 Prolonged prolonged JJ cord-015369-72cjogxz 5480 2 meal meal NN cord-015369-72cjogxz 5480 3 duration duration NN cord-015369-72cjogxz 5480 4 significantly significantly RB cord-015369-72cjogxz 5480 5 contributed contribute VBD cord-015369-72cjogxz 5480 6 to to IN cord-015369-72cjogxz 5480 7 changing change VBG cord-015369-72cjogxz 5480 8 from from IN cord-015369-72cjogxz 5480 9 normal normal JJ cord-015369-72cjogxz 5480 10 to to IN cord-015369-72cjogxz 5480 11 abnormal abnormal JJ cord-015369-72cjogxz 5480 12 score score NN cord-015369-72cjogxz 5480 13 ( ( -LRB- cord-015369-72cjogxz 5480 14 OR or CC cord-015369-72cjogxz 5480 15 3.64 3.64 CD cord-015369-72cjogxz 5480 16 ; ; : cord-015369-72cjogxz 5480 17 95 95 CD cord-015369-72cjogxz 5480 18 % % NN cord-015369-72cjogxz 5480 19 CI CI NNP cord-015369-72cjogxz 5480 20 1.09 1.09 CD cord-015369-72cjogxz 5480 21 - - SYM cord-015369-72cjogxz 5480 22 12.2 12.2 CD cord-015369-72cjogxz 5480 23 , , , cord-015369-72cjogxz 5480 24 p p NN cord-015369-72cjogxz 5480 25 ¼ ¼ CD cord-015369-72cjogxz 5480 26 0.037 0.037 CD cord-015369-72cjogxz 5480 27 ) ) -RRB- cord-015369-72cjogxz 5480 28 . . . cord-015369-72cjogxz 5481 1 The the DT cord-015369-72cjogxz 5481 2 number number NN cord-015369-72cjogxz 5481 3 of of IN cord-015369-72cjogxz 5481 4 acidic acidic JJ cord-015369-72cjogxz 5481 5 foods food NNS cord-015369-72cjogxz 5481 6 consumed consume VBN cord-015369-72cjogxz 5481 7 significantly significantly RB cord-015369-72cjogxz 5481 8 raised raise VBD cord-015369-72cjogxz 5481 9 the the DT cord-015369-72cjogxz 5481 10 probability probability NN cord-015369-72cjogxz 5481 11 to to TO cord-015369-72cjogxz 5481 12 change change VB cord-015369-72cjogxz 5481 13 from from IN cord-015369-72cjogxz 5481 14 abnormal abnormal JJ cord-015369-72cjogxz 5481 15 to to IN cord-015369-72cjogxz 5481 16 normal normal JJ cord-015369-72cjogxz 5481 17 score score NN cord-015369-72cjogxz 5481 18 when when WRB cord-015369-72cjogxz 5481 19 meal meal NN cord-015369-72cjogxz 5481 20 periods period NNS cord-015369-72cjogxz 5481 21 were be VBD cord-015369-72cjogxz 5481 22 excluded exclude VBN cord-015369-72cjogxz 5481 23 ( ( -LRB- cord-015369-72cjogxz 5481 24 OR or CC cord-015369-72cjogxz 5481 25 1.37 1.37 CD cord-015369-72cjogxz 5481 26 ; ; : cord-015369-72cjogxz 5481 27 95 95 CD cord-015369-72cjogxz 5481 28 % % NN cord-015369-72cjogxz 5481 29 CI CI NNP cord-015369-72cjogxz 5481 30 1.01 1.01 CD cord-015369-72cjogxz 5481 31 - - SYM cord-015369-72cjogxz 5481 32 1.86 1.86 CD cord-015369-72cjogxz 5481 33 , , , cord-015369-72cjogxz 5481 34 p p NN cord-015369-72cjogxz 5481 35 ¼ ¼ CD cord-015369-72cjogxz 5481 36 0.04 0.04 CD cord-015369-72cjogxz 5481 37 ) ) -RRB- cord-015369-72cjogxz 5481 38 . . . cord-015369-72cjogxz 5482 1 Conclusions conclusion NNS cord-015369-72cjogxz 5482 2 . . . cord-015369-72cjogxz 5483 1 The the DT cord-015369-72cjogxz 5483 2 exclusion exclusion NN cord-015369-72cjogxz 5483 3 of of IN cord-015369-72cjogxz 5483 4 meal meal NN cord-015369-72cjogxz 5483 5 periods period NNS cord-015369-72cjogxz 5483 6 from from IN cord-015369-72cjogxz 5483 7 24 24 CD cord-015369-72cjogxz 5483 8 h h NN cord-015369-72cjogxz 5483 9 pHmonitoring phmonitoring NN cord-015369-72cjogxz 5483 10 rarely rarely RB cord-015369-72cjogxz 5483 11 resulted result VBD cord-015369-72cjogxz 5483 12 in in IN cord-015369-72cjogxz 5483 13 a a DT cord-015369-72cjogxz 5483 14 different different JJ cord-015369-72cjogxz 5483 15 interpretation interpretation NN cord-015369-72cjogxz 5483 16 of of IN cord-015369-72cjogxz 5483 17 CS CS NNP cord-015369-72cjogxz 5483 18 . . . cord-015369-72cjogxz 5484 1 Ingestion ingestion NN cord-015369-72cjogxz 5484 2 of of IN cord-015369-72cjogxz 5484 3 acidic acidic JJ cord-015369-72cjogxz 5484 4 foods food NNS cord-015369-72cjogxz 5484 5 / / SYM cord-015369-72cjogxz 5484 6 beverages beverage NNS cord-015369-72cjogxz 5484 7 and and CC cord-015369-72cjogxz 5484 8 long long JJ cord-015369-72cjogxz 5484 9 meal meal NN cord-015369-72cjogxz 5484 10 periods period NNS cord-015369-72cjogxz 5484 11 were be VBD cord-015369-72cjogxz 5484 12 identified identify VBN cord-015369-72cjogxz 5484 13 as as IN cord-015369-72cjogxz 5484 14 counteracting counteract VBG cord-015369-72cjogxz 5484 15 independent independent JJ cord-015369-72cjogxz 5484 16 risk risk NN cord-015369-72cjogxz 5484 17 factors factor NNS cord-015369-72cjogxz 5484 18 for for IN cord-015369-72cjogxz 5484 19 crossing cross VBG cord-015369-72cjogxz 5484 20 the the DT cord-015369-72cjogxz 5484 21 cut cut VB cord-015369-72cjogxz 5484 22 - - HYPH cord-015369-72cjogxz 5484 23 off off RP cord-015369-72cjogxz 5484 24 value value NN cord-015369-72cjogxz 5484 25 . . . cord-015369-72cjogxz 5485 1 Colokutane Colokutane NNP cord-015369-72cjogxz 5485 2 Fistel Fistel NNP cord-015369-72cjogxz 5485 3 nach nach NN cord-015369-72cjogxz 5485 4 PEG PEG NNP cord-015369-72cjogxz 5485 5 - - HYPH cord-015369-72cjogxz 5485 6 Anlage Anlage NNP cord-015369-72cjogxz 5485 7 mittels mittels NNP cord-015369-72cjogxz 5485 8 Introducer Introducer NNP cord-015369-72cjogxz 5485 9 - - HYPH cord-015369-72cjogxz 5485 10 Technik Technik NNP cord-015369-72cjogxz 5485 11 mit mit NNP cord-015369-72cjogxz 5485 12 Gastropexie Gastropexie NNP cord-015369-72cjogxz 5485 13 Background Background NNP cord-015369-72cjogxz 5485 14 . . . cord-015369-72cjogxz 5486 1 With with IN cord-015369-72cjogxz 5486 2 a a DT cord-015369-72cjogxz 5486 3 part part NN cord-015369-72cjogxz 5486 4 of of IN cord-015369-72cjogxz 5486 5 1 1 CD cord-015369-72cjogxz 5486 6 percent percent NN cord-015369-72cjogxz 5486 7 of of IN cord-015369-72cjogxz 5486 8 all all DT cord-015369-72cjogxz 5486 9 malignant malignant JJ cord-015369-72cjogxz 5486 10 gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 5486 11 lesions lesion NNS cord-015369-72cjogxz 5486 12 and and CC cord-015369-72cjogxz 5486 13 an an DT cord-015369-72cjogxz 5486 14 incidence incidence NN cord-015369-72cjogxz 5486 15 of of IN cord-015369-72cjogxz 5486 16 1 1 CD cord-015369-72cjogxz 5486 17 - - SYM cord-015369-72cjogxz 5486 18 2 2 CD cord-015369-72cjogxz 5486 19 new new JJ cord-015369-72cjogxz 5486 20 diseases disease NNS cord-015369-72cjogxz 5486 21 referring refer VBG cord-015369-72cjogxz 5486 22 to to IN cord-015369-72cjogxz 5486 23 100 100 CD cord-015369-72cjogxz 5486 24 000 000 CD cord-015369-72cjogxz 5486 25 persons person NNS cord-015369-72cjogxz 5486 26 , , , cord-015369-72cjogxz 5486 27 gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 5486 28 stromal stromal JJ cord-015369-72cjogxz 5486 29 tumors tumor NNS cord-015369-72cjogxz 5486 30 ( ( -LRB- cord-015369-72cjogxz 5486 31 GIST GIST NNP cord-015369-72cjogxz 5486 32 ) ) -RRB- cord-015369-72cjogxz 5486 33 are be VBP cord-015369-72cjogxz 5486 34 rather rather RB cord-015369-72cjogxz 5486 35 rare rare JJ cord-015369-72cjogxz 5486 36 . . . cord-015369-72cjogxz 5487 1 Nevertheless nevertheless RB cord-015369-72cjogxz 5487 2 the the DT cord-015369-72cjogxz 5487 3 number number NN cord-015369-72cjogxz 5487 4 of of IN cord-015369-72cjogxz 5487 5 cases case NNS cord-015369-72cjogxz 5487 6 is be VBZ cord-015369-72cjogxz 5487 7 increasing increase VBG cord-015369-72cjogxz 5487 8 , , , cord-015369-72cjogxz 5487 9 belonging belong VBG cord-015369-72cjogxz 5487 10 to to IN cord-015369-72cjogxz 5487 11 better well JJR cord-015369-72cjogxz 5487 12 endoscopic endoscopic NNS cord-015369-72cjogxz 5487 13 and and CC cord-015369-72cjogxz 5487 14 radiological radiological JJ cord-015369-72cjogxz 5487 15 methods method NNS cord-015369-72cjogxz 5487 16 , , , cord-015369-72cjogxz 5487 17 but but CC cord-015369-72cjogxz 5487 18 also also RB cord-015369-72cjogxz 5487 19 because because IN cord-015369-72cjogxz 5487 20 of of IN cord-015369-72cjogxz 5487 21 the the DT cord-015369-72cjogxz 5487 22 better well JJR cord-015369-72cjogxz 5487 23 knowledgement knowledgement NNP cord-015369-72cjogxz 5487 24 in in IN cord-015369-72cjogxz 5487 25 histopathologic histopathologic NNP cord-015369-72cjogxz 5487 26 and and CC cord-015369-72cjogxz 5487 27 moleculargenetic moleculargenetic JJ cord-015369-72cjogxz 5487 28 examinations examination NNS cord-015369-72cjogxz 5487 29 . . . cord-015369-72cjogxz 5488 1 Methods method NNS cord-015369-72cjogxz 5488 2 . . . cord-015369-72cjogxz 5489 1 In in IN cord-015369-72cjogxz 5489 2 2008 2008 CD cord-015369-72cjogxz 5489 3 a a DT cord-015369-72cjogxz 5489 4 group group NN cord-015369-72cjogxz 5489 5 of of IN cord-015369-72cjogxz 5489 6 two two CD cord-015369-72cjogxz 5489 7 surgeons surgeon NNS cord-015369-72cjogxz 5489 8 and and CC cord-015369-72cjogxz 5489 9 two two CD cord-015369-72cjogxz 5489 10 oncologists oncologist NNS cord-015369-72cjogxz 5489 11 , , , cord-015369-72cjogxz 5489 12 started start VBD cord-015369-72cjogxz 5489 13 to to TO cord-015369-72cjogxz 5489 14 discuss discuss VB cord-015369-72cjogxz 5489 15 about about IN cord-015369-72cjogxz 5489 16 a a DT cord-015369-72cjogxz 5489 17 national national JJ cord-015369-72cjogxz 5489 18 registration registration NN cord-015369-72cjogxz 5489 19 of of IN cord-015369-72cjogxz 5489 20 patients patient NNS cord-015369-72cjogxz 5489 21 suffering suffer VBG cord-015369-72cjogxz 5489 22 from from IN cord-015369-72cjogxz 5489 23 GIST GIST NNP cord-015369-72cjogxz 5489 24 in in IN cord-015369-72cjogxz 5489 25 Austria Austria NNP cord-015369-72cjogxz 5489 26 . . . cord-015369-72cjogxz 5490 1 Criterions criterion NNS cord-015369-72cjogxz 5490 2 for for IN cord-015369-72cjogxz 5490 3 registration registration NN cord-015369-72cjogxz 5490 4 were be VBD cord-015369-72cjogxz 5490 5 discussed discuss VBN cord-015369-72cjogxz 5490 6 and and CC cord-015369-72cjogxz 5490 7 fixed fix VBN cord-015369-72cjogxz 5490 8 up up RP cord-015369-72cjogxz 5490 9 in in IN cord-015369-72cjogxz 5490 10 a a DT cord-015369-72cjogxz 5490 11 sheet sheet NN cord-015369-72cjogxz 5490 12 . . . cord-015369-72cjogxz 5491 1 Also also RB cord-015369-72cjogxz 5491 2 an an DT cord-015369-72cjogxz 5491 3 informed informed JJ cord-015369-72cjogxz 5491 4 consent consent NN cord-015369-72cjogxz 5491 5 for for IN cord-015369-72cjogxz 5491 6 the the DT cord-015369-72cjogxz 5491 7 patients patient NNS cord-015369-72cjogxz 5491 8 registration registration NN cord-015369-72cjogxz 5491 9 was be VBD cord-015369-72cjogxz 5491 10 conceived conceive VBN cord-015369-72cjogxz 5491 11 . . . cord-015369-72cjogxz 5492 1 Our -PRON- PRP$ cord-015369-72cjogxz 5492 2 concept concept NN cord-015369-72cjogxz 5492 3 , , , cord-015369-72cjogxz 5492 4 aims aim VBZ cord-015369-72cjogxz 5492 5 and and CC cord-015369-72cjogxz 5492 6 visions vision NNS cord-015369-72cjogxz 5492 7 were be VBD cord-015369-72cjogxz 5492 8 presented present VBN cord-015369-72cjogxz 5492 9 at at IN cord-015369-72cjogxz 5492 10 the the DT cord-015369-72cjogxz 5492 11 commission commission NNP cord-015369-72cjogxz 5492 12 of of IN cord-015369-72cjogxz 5492 13 ethics ethic NNS cord-015369-72cjogxz 5492 14 in in IN cord-015369-72cjogxz 5492 15 lower low JJR cord-015369-72cjogxz 5492 16 Austria Austria NNP cord-015369-72cjogxz 5492 17 , , , cord-015369-72cjogxz 5492 18 and and CC cord-015369-72cjogxz 5492 19 a a DT cord-015369-72cjogxz 5492 20 positive positive JJ cord-015369-72cjogxz 5492 21 votum votum NN cord-015369-72cjogxz 5492 22 was be VBD cord-015369-72cjogxz 5492 23 given give VBN cord-015369-72cjogxz 5492 24 at at IN cord-015369-72cjogxz 5492 25 the the DT cord-015369-72cjogxz 5492 26 end end NN cord-015369-72cjogxz 5492 27 of of IN cord-015369-72cjogxz 5492 28 2008 2008 CD cord-015369-72cjogxz 5492 29 . . . cord-015369-72cjogxz 5493 1 So so RB cord-015369-72cjogxz 5493 2 we -PRON- PRP cord-015369-72cjogxz 5493 3 started start VBD cord-015369-72cjogxz 5493 4 our -PRON- PRP$ cord-015369-72cjogxz 5493 5 official official JJ cord-015369-72cjogxz 5493 6 work work NN cord-015369-72cjogxz 5493 7 at at IN cord-015369-72cjogxz 5493 8 the the DT cord-015369-72cjogxz 5493 9 first first JJ cord-015369-72cjogxz 5493 10 of of IN cord-015369-72cjogxz 5493 11 January January NNP cord-015369-72cjogxz 5493 12 2009 2009 CD cord-015369-72cjogxz 5493 13 . . . cord-015369-72cjogxz 5494 1 Results result NNS cord-015369-72cjogxz 5494 2 . . . cord-015369-72cjogxz 5495 1 As as IN cord-015369-72cjogxz 5495 2 well well RB cord-015369-72cjogxz 5495 3 the the DT cord-015369-72cjogxz 5495 4 oncologist oncologist NN cord-015369-72cjogxz 5495 5 team team NN cord-015369-72cjogxz 5495 6 as as IN cord-015369-72cjogxz 5495 7 the the DT cord-015369-72cjogxz 5495 8 surgeon surgeon NN cord-015369-72cjogxz 5495 9 group group NN cord-015369-72cjogxz 5495 10 contacted contact VBD cord-015369-72cjogxz 5495 11 as as IN cord-015369-72cjogxz 5495 12 much much JJ cord-015369-72cjogxz 5495 13 centres centre NNS cord-015369-72cjogxz 5495 14 as as IN cord-015369-72cjogxz 5495 15 possible possible JJ cord-015369-72cjogxz 5495 16 by by IN cord-015369-72cjogxz 5495 17 phone phone NN cord-015369-72cjogxz 5495 18 call call NN cord-015369-72cjogxz 5495 19 or or CC cord-015369-72cjogxz 5495 20 by by IN cord-015369-72cjogxz 5495 21 letter letter NN cord-015369-72cjogxz 5495 22 , , , cord-015369-72cjogxz 5495 23 inviting invite VBG cord-015369-72cjogxz 5495 24 them -PRON- PRP cord-015369-72cjogxz 5495 25 to to TO cord-015369-72cjogxz 5495 26 support support VB cord-015369-72cjogxz 5495 27 the the DT cord-015369-72cjogxz 5495 28 registry registry NN cord-015369-72cjogxz 5495 29 by by IN cord-015369-72cjogxz 5495 30 bringing bring VBG cord-015369-72cjogxz 5495 31 in in RP cord-015369-72cjogxz 5495 32 their -PRON- PRP$ cord-015369-72cjogxz 5495 33 data datum NNS cord-015369-72cjogxz 5495 34 . . . cord-015369-72cjogxz 5496 1 In in IN cord-015369-72cjogxz 5496 2 a a DT cord-015369-72cjogxz 5496 3 short short JJ cord-015369-72cjogxz 5496 4 time time NN cord-015369-72cjogxz 5496 5 about about RB cord-015369-72cjogxz 5496 6 30 30 CD cord-015369-72cjogxz 5496 7 centres centre NNS cord-015369-72cjogxz 5496 8 and and CC cord-015369-72cjogxz 5496 9 also also RB cord-015369-72cjogxz 5496 10 the the DT cord-015369-72cjogxz 5496 11 contact contact NN cord-015369-72cjogxz 5496 12 persons person NNS cord-015369-72cjogxz 5496 13 were be VBD cord-015369-72cjogxz 5496 14 registered register VBN cord-015369-72cjogxz 5496 15 . . . cord-015369-72cjogxz 5497 1 In in IN cord-015369-72cjogxz 5497 2 a a DT cord-015369-72cjogxz 5497 3 second second JJ cord-015369-72cjogxz 5497 4 announcement announcement NN cord-015369-72cjogxz 5497 5 we -PRON- PRP cord-015369-72cjogxz 5497 6 want want VBP cord-015369-72cjogxz 5497 7 to to TO cord-015369-72cjogxz 5497 8 enlarge enlarge VB cord-015369-72cjogxz 5497 9 this this DT cord-015369-72cjogxz 5497 10 number number NN cord-015369-72cjogxz 5497 11 in in IN cord-015369-72cjogxz 5497 12 order order NN cord-015369-72cjogxz 5497 13 to to TO cord-015369-72cjogxz 5497 14 get get VB cord-015369-72cjogxz 5497 15 better well JJR cord-015369-72cjogxz 5497 16 results result NNS cord-015369-72cjogxz 5497 17 . . . cord-015369-72cjogxz 5498 1 Conclusions conclusion NNS cord-015369-72cjogxz 5498 2 . . . cord-015369-72cjogxz 5499 1 GIST gist NN cord-015369-72cjogxz 5499 2 registry registry NN cord-015369-72cjogxz 5499 3 was be VBD cord-015369-72cjogxz 5499 4 started start VBN cord-015369-72cjogxz 5499 5 to to TO cord-015369-72cjogxz 5499 6 find find VB cord-015369-72cjogxz 5499 7 out out RP cord-015369-72cjogxz 5499 8 incidence incidence NN cord-015369-72cjogxz 5499 9 of of IN cord-015369-72cjogxz 5499 10 disease disease NN cord-015369-72cjogxz 5499 11 , , , cord-015369-72cjogxz 5499 12 but but CC cord-015369-72cjogxz 5499 13 also also RB cord-015369-72cjogxz 5499 14 the the DT cord-015369-72cjogxz 5499 15 way way NN cord-015369-72cjogxz 5499 16 of of IN cord-015369-72cjogxz 5499 17 diagnosis diagnosis NN cord-015369-72cjogxz 5499 18 and and CC cord-015369-72cjogxz 5499 19 therapy therapy NN cord-015369-72cjogxz 5499 20 in in IN cord-015369-72cjogxz 5499 21 patients patient NNS cord-015369-72cjogxz 5499 22 in in IN cord-015369-72cjogxz 5499 23 Austria Austria NNP cord-015369-72cjogxz 5499 24 . . . cord-015369-72cjogxz 5500 1 Do do VBP cord-015369-72cjogxz 5500 2 we -PRON- PRP cord-015369-72cjogxz 5500 3 have have VB cord-015369-72cjogxz 5500 4 similar similar JJ cord-015369-72cjogxz 5500 5 strategies strategy NNS cord-015369-72cjogxz 5500 6 in in IN cord-015369-72cjogxz 5500 7 the the DT cord-015369-72cjogxz 5500 8 ( ( -LRB- cord-015369-72cjogxz 5500 9 neo- neo- NN cord-015369-72cjogxz 5500 10 ) ) -RRB- cord-015369-72cjogxz 5500 11 adjuvant adjuvant JJ cord-015369-72cjogxz 5500 12 setting setting NN cord-015369-72cjogxz 5500 13 and and CC cord-015369-72cjogxz 5500 14 in in IN cord-015369-72cjogxz 5500 15 treating treat VBG cord-015369-72cjogxz 5500 16 metastatic metastatic JJ cord-015369-72cjogxz 5500 17 ore ore NN cord-015369-72cjogxz 5500 18 advanced advanced JJ cord-015369-72cjogxz 5500 19 disease disease NN cord-015369-72cjogxz 5500 20 or or CC cord-015369-72cjogxz 5500 21 not not RB cord-015369-72cjogxz 5500 22 ? ? . cord-015369-72cjogxz 5501 1 Colonic colonic JJ cord-015369-72cjogxz 5501 2 retrosternal retrosternal JJ cord-015369-72cjogxz 5501 3 esophagoplasty esophagoplasty NN cord-015369-72cjogxz 5501 4 in in IN cord-015369-72cjogxz 5501 5 young young JJ cord-015369-72cjogxz 5501 6 children child NNS cord-015369-72cjogxz 5501 7 with with IN cord-015369-72cjogxz 5501 8 pure pure JJ cord-015369-72cjogxz 5501 9 esophageal esophageal JJ cord-015369-72cjogxz 5501 10 atresia atresia NN cord-015369-72cjogxz 5501 11 R. R. NNP cord-015369-72cjogxz 5501 12 Kovalskyy Kovalskyy NNP cord-015369-72cjogxz 5501 13 1 1 CD cord-015369-72cjogxz 5501 14 , , , cord-015369-72cjogxz 5501 15 A. A. NNP cord-015369-72cjogxz 5501 16 Kuzyk Kuzyk NNP cord-015369-72cjogxz 5501 17 2 2 CD cord-015369-72cjogxz 5501 18 , , , cord-015369-72cjogxz 5501 19 O. O. NNP cord-015369-72cjogxz 5501 20 Leniv Leniv NNP cord-015369-72cjogxz 5501 21 1 1 CD cord-015369-72cjogxz 5501 22 , , , cord-015369-72cjogxz 5501 23 I. I. NNP cord-015369-72cjogxz 5501 24 Avramenko Avramenko NNP cord-015369-72cjogxz 5501 25 1 1 CD cord-015369-72cjogxz 5501 26 1 1 CD cord-015369-72cjogxz 5501 27 Lviv Lviv NNP cord-015369-72cjogxz 5501 28 Regional Regional NNP cord-015369-72cjogxz 5501 29 Children Children NNPS cord-015369-72cjogxz 5501 30 Hospital Hospital NNP cord-015369-72cjogxz 5501 31 ' ' POS cord-015369-72cjogxz 5501 32 ' ' `` cord-015369-72cjogxz 5501 33 OHMATDYT OHMATDYT NNP cord-015369-72cjogxz 5501 34 ' ' '' cord-015369-72cjogxz 5501 35 ' ' '' cord-015369-72cjogxz 5501 36 , , , cord-015369-72cjogxz 5501 37 Department Department NNP cord-015369-72cjogxz 5501 38 of of IN cord-015369-72cjogxz 5501 39 Pediatric Pediatric NNP cord-015369-72cjogxz 5501 40 Surgery Surgery NNP cord-015369-72cjogxz 5501 41 , , , cord-015369-72cjogxz 5501 42 Lviv Lviv NNP cord-015369-72cjogxz 5501 43 , , , cord-015369-72cjogxz 5501 44 Ukraine Ukraine NNP cord-015369-72cjogxz 5501 45 ; ; , cord-015369-72cjogxz 5501 46 2 2 CD cord-015369-72cjogxz 5501 47 Department Department NNP cord-015369-72cjogxz 5501 48 of of IN cord-015369-72cjogxz 5501 49 Pediatric Pediatric NNP cord-015369-72cjogxz 5501 50 Surgery Surgery NNP cord-015369-72cjogxz 5501 51 , , , cord-015369-72cjogxz 5501 52 Lviv Lviv NNP cord-015369-72cjogxz 5501 53 National National NNP cord-015369-72cjogxz 5501 54 Medical Medical NNP cord-015369-72cjogxz 5501 55 University University NNP cord-015369-72cjogxz 5501 56 , , , cord-015369-72cjogxz 5501 57 Lviv Lviv NNP cord-015369-72cjogxz 5501 58 , , , cord-015369-72cjogxz 5501 59 Ukraine Ukraine NNP cord-015369-72cjogxz 5501 60 Background Background NNP cord-015369-72cjogxz 5501 61 . . . cord-015369-72cjogxz 5502 1 Pure pure JJ cord-015369-72cjogxz 5502 2 esophageal esophageal JJ cord-015369-72cjogxz 5502 3 atresia atresia NN cord-015369-72cjogxz 5502 4 is be VBZ cord-015369-72cjogxz 5502 5 observed observe VBN cord-015369-72cjogxz 5502 6 in in IN cord-015369-72cjogxz 5502 7 8 8 CD cord-015369-72cjogxz 5502 8 - - SYM cord-015369-72cjogxz 5502 9 12 12 CD cord-015369-72cjogxz 5502 10 % % NN cord-015369-72cjogxz 5502 11 of of IN cord-015369-72cjogxz 5502 12 the the DT cord-015369-72cjogxz 5502 13 newborn newborn NN cord-015369-72cjogxz 5502 14 with with IN cord-015369-72cjogxz 5502 15 the the DT cord-015369-72cjogxz 5502 16 mentioned mention VBN cord-015369-72cjogxz 5502 17 pathology pathology NN cord-015369-72cjogxz 5502 18 . . . cord-015369-72cjogxz 5503 1 There there EX cord-015369-72cjogxz 5503 2 is be VBZ cord-015369-72cjogxz 5503 3 still still RB cord-015369-72cjogxz 5503 4 a a DT cord-015369-72cjogxz 5503 5 search search NN cord-015369-72cjogxz 5503 6 for for IN cord-015369-72cjogxz 5503 7 the the DT cord-015369-72cjogxz 5503 8 optimal optimal JJ cord-015369-72cjogxz 5503 9 problem problem NN cord-015369-72cjogxz 5503 10 solving solve VBG cord-015369-72cjogxz 5503 11 of of IN cord-015369-72cjogxz 5503 12 the the DT cord-015369-72cjogxz 5503 13 esophagus esophagus NN cord-015369-72cjogxz 5503 14 patency patency NN cord-015369-72cjogxz 5503 15 correction correction NN cord-015369-72cjogxz 5503 16 in in IN cord-015369-72cjogxz 5503 17 such such JJ cord-015369-72cjogxz 5503 18 patients patient NNS cord-015369-72cjogxz 5503 19 . . . cord-015369-72cjogxz 5504 1 This this DT cord-015369-72cjogxz 5504 2 concerns concern VBZ cord-015369-72cjogxz 5504 3 both both CC cord-015369-72cjogxz 5504 4 the the DT cord-015369-72cjogxz 5504 5 choice choice NN cord-015369-72cjogxz 5504 6 of of IN cord-015369-72cjogxz 5504 7 methods method NNS cord-015369-72cjogxz 5504 8 and and CC cord-015369-72cjogxz 5504 9 the the DT cord-015369-72cjogxz 5504 10 age age NN cord-015369-72cjogxz 5504 11 of of IN cord-015369-72cjogxz 5504 12 the the DT cord-015369-72cjogxz 5504 13 children child NNS cord-015369-72cjogxz 5504 14 . . . cord-015369-72cjogxz 5505 1 Methods method NNS cord-015369-72cjogxz 5505 2 . . . cord-015369-72cjogxz 5506 1 Since since IN cord-015369-72cjogxz 5506 2 1989 1989 CD cord-015369-72cjogxz 5506 3 till till IN cord-015369-72cjogxz 5506 4 2007 2007 CD cord-015369-72cjogxz 5506 5 11 11 CD cord-015369-72cjogxz 5506 6 colonic colonic JJ cord-015369-72cjogxz 5506 7 retrosternal retrosternal JJ cord-015369-72cjogxz 5506 8 esophagoplasty esophagoplasty NNP cord-015369-72cjogxz 5506 9 have have VBP cord-015369-72cjogxz 5506 10 been be VBN cord-015369-72cjogxz 5506 11 done do VBN cord-015369-72cjogxz 5506 12 . . . cord-015369-72cjogxz 5507 1 The the DT cord-015369-72cjogxz 5507 2 newborns newborn NNS cord-015369-72cjogxz 5507 3 weight weight NN cord-015369-72cjogxz 5507 4 was be VBD cord-015369-72cjogxz 5507 5 2400 2400 CD cord-015369-72cjogxz 5507 6 - - SYM cord-015369-72cjogxz 5507 7 2850 2850 CD cord-015369-72cjogxz 5507 8 g. g. NNP cord-015369-72cjogxz 5507 9 7 7 CD cord-015369-72cjogxz 5507 10 children child NNS cord-015369-72cjogxz 5507 11 - - HYPH cord-015369-72cjogxz 5507 12 born bear VBN cord-015369-72cjogxz 5507 13 prematurely prematurely RB cord-015369-72cjogxz 5507 14 . . . cord-015369-72cjogxz 5508 1 9 9 CD cord-015369-72cjogxz 5508 2 newborns newborn NNS cord-015369-72cjogxz 5508 3 had have VBD cord-015369-72cjogxz 5508 4 pneumonia pneumonia NN cord-015369-72cjogxz 5508 5 . . . cord-015369-72cjogxz 5509 1 Diastases diastasis NNS cord-015369-72cjogxz 5509 2 between between IN cord-015369-72cjogxz 5509 3 the the DT cord-015369-72cjogxz 5509 4 esophagus esophagus NN cord-015369-72cjogxz 5509 5 segments segment NNS cord-015369-72cjogxz 5509 6 equaled equal VBD cord-015369-72cjogxz 5509 7 6 6 CD cord-015369-72cjogxz 5509 8 - - SYM cord-015369-72cjogxz 5509 9 7 7 CD cord-015369-72cjogxz 5509 10 cm cm NN cord-015369-72cjogxz 5509 11 . . . cord-015369-72cjogxz 5510 1 At at IN cord-015369-72cjogxz 5510 2 the the DT cord-015369-72cjogxz 5510 3 moment moment NN cord-015369-72cjogxz 5510 4 of of IN cord-015369-72cjogxz 5510 5 operation operation NN cord-015369-72cjogxz 5510 6 the the DT cord-015369-72cjogxz 5510 7 children child NNS cord-015369-72cjogxz 5510 8 were be VBD cord-015369-72cjogxz 5510 9 of of IN cord-015369-72cjogxz 5510 10 4 4 CD cord-015369-72cjogxz 5510 11 - - SYM cord-015369-72cjogxz 5510 12 16 16 CD cord-015369-72cjogxz 5510 13 weeks week NNS cord-015369-72cjogxz 5510 14 old old JJ cord-015369-72cjogxz 5510 15 . . . cord-015369-72cjogxz 5511 1 Body body NN cord-015369-72cjogxz 5511 2 weight weight NN cord-015369-72cjogxz 5511 3 was be VBD cord-015369-72cjogxz 5511 4 3100 3100 CD cord-015369-72cjogxz 5511 5 - - SYM cord-015369-72cjogxz 5511 6 4500 4500 CD cord-015369-72cjogxz 5511 7 g. g. NN cord-015369-72cjogxz 5512 1 During during IN cord-015369-72cjogxz 5512 2 the the DT cord-015369-72cjogxz 5512 3 first first JJ cord-015369-72cjogxz 5512 4 three three CD cord-015369-72cjogxz 5512 5 weeks week NNS cord-015369-72cjogxz 5512 6 the the DT cord-015369-72cjogxz 5512 7 newborns newborn NNS cord-015369-72cjogxz 5512 8 had have VBD cord-015369-72cjogxz 5512 9 the the DT cord-015369-72cjogxz 5512 10 distal distal JJ cord-015369-72cjogxz 5512 11 esophagostomy esophagostomy NN cord-015369-72cjogxz 5512 12 in in IN cord-015369-72cjogxz 5512 13 the the DT cord-015369-72cjogxz 5512 14 necks neck NNS cord-015369-72cjogxz 5512 15 and and CC cord-015369-72cjogxz 5512 16 gastrostomy gastrostomy NN cord-015369-72cjogxz 5512 17 . . . cord-015369-72cjogxz 5513 1 When when WRB cord-015369-72cjogxz 5513 2 the the DT cord-015369-72cjogxz 5513 3 weight weight NN cord-015369-72cjogxz 5513 4 was be VBD cord-015369-72cjogxz 5513 5 stably stably RB cord-015369-72cjogxz 5513 6 increasing increase VBG cord-015369-72cjogxz 5513 7 , , , cord-015369-72cjogxz 5513 8 the the DT cord-015369-72cjogxz 5513 9 patients patient NNS cord-015369-72cjogxz 5513 10 had have VBD cord-015369-72cjogxz 5513 11 a a DT cord-015369-72cjogxz 5513 12 laparotomy laparotomy NN cord-015369-72cjogxz 5513 13 , , , cord-015369-72cjogxz 5513 14 the the DT cord-015369-72cjogxz 5513 15 segment segment NN cord-015369-72cjogxz 5513 16 of of IN cord-015369-72cjogxz 5513 17 colon colon NN cord-015369-72cjogxz 5513 18 was be VBD cord-015369-72cjogxz 5513 19 chosen choose VBN cord-015369-72cjogxz 5513 20 for for IN cord-015369-72cjogxz 5513 21 transplantation transplantation NN cord-015369-72cjogxz 5513 22 . . . cord-015369-72cjogxz 5514 1 Usually usually RB cord-015369-72cjogxz 5514 2 it -PRON- PRP cord-015369-72cjogxz 5514 3 was be VBD cord-015369-72cjogxz 5514 4 a a DT cord-015369-72cjogxz 5514 5 colon colon NN cord-015369-72cjogxz 5514 6 transversum transversum NN cord-015369-72cjogxz 5514 7 and and CC cord-015369-72cjogxz 5514 8 a a DT cord-015369-72cjogxz 5514 9 part part NN cord-015369-72cjogxz 5514 10 of of IN cord-015369-72cjogxz 5514 11 colon colon NN cord-015369-72cjogxz 5514 12 descendens descenden NNS cord-015369-72cjogxz 5514 13 with with IN cord-015369-72cjogxz 5514 14 a. a. NN cord-015369-72cjogxz 5514 15 colica colica NNP cord-015369-72cjogxz 5514 16 sinistra sinistra NNP cord-015369-72cjogxz 5514 17 . . . cord-015369-72cjogxz 5515 1 Transplant transplant NN cord-015369-72cjogxz 5515 2 was be VBD cord-015369-72cjogxz 5515 3 put put VBN cord-015369-72cjogxz 5515 4 behind behind IN cord-015369-72cjogxz 5515 5 the the DT cord-015369-72cjogxz 5515 6 stomach stomach NN cord-015369-72cjogxz 5515 7 and and CC cord-015369-72cjogxz 5515 8 located locate VBN cord-015369-72cjogxz 5515 9 retrosternally retrosternally RB cord-015369-72cjogxz 5515 10 in in IN cord-015369-72cjogxz 5515 11 anterior anterior JJ cord-015369-72cjogxz 5515 12 mediastinum mediastinum FW cord-015369-72cjogxz 5515 13 . . . cord-015369-72cjogxz 5516 1 Proximal proximal JJ cord-015369-72cjogxz 5516 2 transplant transplant NN cord-015369-72cjogxz 5516 3 ending ending NN cord-015369-72cjogxz 5516 4 was be VBD cord-015369-72cjogxz 5516 5 sewed sew VBN cord-015369-72cjogxz 5516 6 in in IN cord-015369-72cjogxz 5516 7 the the DT cord-015369-72cjogxz 5516 8 anterior anterior JJ cord-015369-72cjogxz 5516 9 wall wall NN cord-015369-72cjogxz 5516 10 of of IN cord-015369-72cjogxz 5516 11 stomach stomach NN cord-015369-72cjogxz 5516 12 , , , cord-015369-72cjogxz 5516 13 distal distal JJ cord-015369-72cjogxz 5516 14 - - : cord-015369-72cjogxz 5516 15 was be VBD cord-015369-72cjogxz 5516 16 delivered deliver VBN cord-015369-72cjogxz 5516 17 to to IN cord-015369-72cjogxz 5516 18 the the DT cord-015369-72cjogxz 5516 19 neck neck NN cord-015369-72cjogxz 5516 20 next next JJ cord-015369-72cjogxz 5516 21 to to IN cord-015369-72cjogxz 5516 22 esophagostoma esophagostoma NNP cord-015369-72cjogxz 5516 23 , , , cord-015369-72cjogxz 5516 24 in in IN cord-015369-72cjogxz 5516 25 2 2 CD cord-015369-72cjogxz 5516 26 - - SYM cord-015369-72cjogxz 5516 27 3 3 CD cord-015369-72cjogxz 5516 28 weeks week NNS cord-015369-72cjogxz 5516 29 - - : cord-015369-72cjogxz 5516 30 the the DT cord-015369-72cjogxz 5516 31 anastomosis anastomosis NN cord-015369-72cjogxz 5516 32 with with IN cord-015369-72cjogxz 5516 33 esophagus esophagus NN cord-015369-72cjogxz 5516 34 . . . cord-015369-72cjogxz 5517 1 Results result NNS cord-015369-72cjogxz 5517 2 . . . cord-015369-72cjogxz 5518 1 Four four CD cord-015369-72cjogxz 5518 2 patients patient NNS cord-015369-72cjogxz 5518 3 had have VBD cord-015369-72cjogxz 5518 4 an an DT cord-015369-72cjogxz 5518 5 anastomotic anastomotic JJ cord-015369-72cjogxz 5518 6 breakdown breakdown NN cord-015369-72cjogxz 5518 7 in in IN cord-015369-72cjogxz 5518 8 the the DT cord-015369-72cjogxz 5518 9 neck neck NN cord-015369-72cjogxz 5518 10 . . . cord-015369-72cjogxz 5519 1 Two two CD cord-015369-72cjogxz 5519 2 of of IN cord-015369-72cjogxz 5519 3 them -PRON- PRP cord-015369-72cjogxz 5519 4 had have VBD cord-015369-72cjogxz 5519 5 the the DT cord-015369-72cjogxz 5519 6 repeated repeat VBN cord-015369-72cjogxz 5519 7 cervical cervical JJ cord-015369-72cjogxz 5519 8 anastomosis anastomosis NN cord-015369-72cjogxz 5519 9 , , , cord-015369-72cjogxz 5519 10 the the DT cord-015369-72cjogxz 5519 11 others other NNS cord-015369-72cjogxz 5519 12 had have VBD cord-015369-72cjogxz 5519 13 fistula fistula NN cord-015369-72cjogxz 5519 14 , , , cord-015369-72cjogxz 5519 15 which which WDT cord-015369-72cjogxz 5519 16 closed close VBD cord-015369-72cjogxz 5519 17 by by IN cord-015369-72cjogxz 5519 18 itself -PRON- PRP cord-015369-72cjogxz 5519 19 . . . cord-015369-72cjogxz 5520 1 The the DT cord-015369-72cjogxz 5520 2 children child NNS cord-015369-72cjogxz 5520 3 had have VBD cord-015369-72cjogxz 5520 4 a a DT cord-015369-72cjogxz 5520 5 good good JJ cord-015369-72cjogxz 5520 6 passage passage NN cord-015369-72cjogxz 5520 7 in in IN cord-015369-72cjogxz 5520 8 the the DT cord-015369-72cjogxz 5520 9 transplant transplant NN cord-015369-72cjogxz 5520 10 . . . cord-015369-72cjogxz 5521 1 Conclusions conclusion NNS cord-015369-72cjogxz 5521 2 . . . cord-015369-72cjogxz 5522 1 To to TO cord-015369-72cjogxz 5522 2 treat treat VB cord-015369-72cjogxz 5522 3 the the DT cord-015369-72cjogxz 5522 4 children child NNS cord-015369-72cjogxz 5522 5 with with IN cord-015369-72cjogxz 5522 6 pure pure JJ cord-015369-72cjogxz 5522 7 esophageal esophageal JJ cord-015369-72cjogxz 5522 8 atresia atresia NN cord-015369-72cjogxz 5522 9 without without IN cord-015369-72cjogxz 5522 10 fistula fistula NN cord-015369-72cjogxz 5522 11 it -PRON- PRP cord-015369-72cjogxz 5522 12 is be VBZ cord-015369-72cjogxz 5522 13 possible possible JJ cord-015369-72cjogxz 5522 14 to to TO cord-015369-72cjogxz 5522 15 use use VB cord-015369-72cjogxz 5522 16 successfully successfully RB cord-015369-72cjogxz 5522 17 colonic colonic JJ cord-015369-72cjogxz 5522 18 retrosternal retrosternal JJ cord-015369-72cjogxz 5522 19 esophagoplasty esophagoplasty NN cord-015369-72cjogxz 5522 20 in in IN cord-015369-72cjogxz 5522 21 the the DT cord-015369-72cjogxz 5522 22 early early JJ cord-015369-72cjogxz 5522 23 age age NN cord-015369-72cjogxz 5522 24 . . . cord-015369-72cjogxz 5523 1 Background background NN cord-015369-72cjogxz 5523 2 . . . cord-015369-72cjogxz 5524 1 Gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 5524 2 reflux reflux NN cord-015369-72cjogxz 5524 3 disease disease NN cord-015369-72cjogxz 5524 4 is be VBZ cord-015369-72cjogxz 5524 5 associated associate VBN cord-015369-72cjogxz 5524 6 with with IN cord-015369-72cjogxz 5524 7 columnar columnar JJ cord-015369-72cjogxz 5524 8 lined line VBN cord-015369-72cjogxz 5524 9 esophagus esophagu NNS cord-015369-72cjogxz 5524 10 ( ( -LRB- cord-015369-72cjogxz 5524 11 CLE CLE NNP cord-015369-72cjogxz 5524 12 ) ) -RRB- cord-015369-72cjogxz 5524 13 . . . cord-015369-72cjogxz 5525 1 We -PRON- PRP cord-015369-72cjogxz 5525 2 aim aim VBP cord-015369-72cjogxz 5525 3 to to TO cord-015369-72cjogxz 5525 4 summarize summarize VB cord-015369-72cjogxz 5525 5 the the DT cord-015369-72cjogxz 5525 6 novel novel JJ cord-015369-72cjogxz 5525 7 developments development NNS cord-015369-72cjogxz 5525 8 regarding regard VBG cord-015369-72cjogxz 5525 9 our -PRON- PRP$ cord-015369-72cjogxz 5525 10 understanding understanding NN cord-015369-72cjogxz 5525 11 of of IN cord-015369-72cjogxz 5525 12 CLE CLE NNP cord-015369-72cjogxz 5525 13 . . . cord-015369-72cjogxz 5526 1 Methods method NNS cord-015369-72cjogxz 5526 2 . . . cord-015369-72cjogxz 5527 1 Review Review NNP cord-015369-72cjogxz 5527 2 of of IN cord-015369-72cjogxz 5527 3 the the DT cord-015369-72cjogxz 5527 4 recent recent JJ cord-015369-72cjogxz 5527 5 literature literature NN cord-015369-72cjogxz 5527 6 ( ( -LRB- cord-015369-72cjogxz 5527 7 2006 2006 CD cord-015369-72cjogxz 5527 8 - - SYM cord-015369-72cjogxz 5527 9 2009 2009 CD cord-015369-72cjogxz 5527 10 ) ) -RRB- cord-015369-72cjogxz 5527 11 on on IN cord-015369-72cjogxz 5527 12 CLE CLE NNP cord-015369-72cjogxz 5527 13 . . . cord-015369-72cjogxz 5528 1 Results result NNS cord-015369-72cjogxz 5528 2 . . . cord-015369-72cjogxz 5529 1 Gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 5529 2 reflux reflux NN cord-015369-72cjogxz 5529 3 causes cause VBZ cord-015369-72cjogxz 5529 4 damage damage NN cord-015369-72cjogxz 5529 5 and and CC cord-015369-72cjogxz 5529 6 columnar columnar JJ cord-015369-72cjogxz 5529 7 metaplasia metaplasia NN cord-015369-72cjogxz 5529 8 of of IN cord-015369-72cjogxz 5529 9 the the DT cord-015369-72cjogxz 5529 10 squamous squamous JJ cord-015369-72cjogxz 5529 11 mucosa mucosa NN cord-015369-72cjogxz 5529 12 of of IN cord-015369-72cjogxz 5529 13 the the DT cord-015369-72cjogxz 5529 14 esophagus esophagus NN cord-015369-72cjogxz 5529 15 resulting result VBG cord-015369-72cjogxz 5529 16 in in IN cord-015369-72cjogxz 5529 17 the the DT cord-015369-72cjogxz 5529 18 formation formation NN cord-015369-72cjogxz 5529 19 of of IN cord-015369-72cjogxz 5529 20 columnar columnar JJ cord-015369-72cjogxz 5529 21 lined line VBN cord-015369-72cjogxz 5529 22 esophagus esophagu NNS cord-015369-72cjogxz 5529 23 ( ( -LRB- cord-015369-72cjogxz 5529 24 CLE CLE NNP cord-015369-72cjogxz 5529 25 ) ) -RRB- cord-015369-72cjogxz 5529 26 . . . cord-015369-72cjogxz 5530 1 Recent recent JJ cord-015369-72cjogxz 5530 2 evidence evidence NN cord-015369-72cjogxz 5530 3 indicates indicate VBZ cord-015369-72cjogxz 5530 4 that that IN cord-015369-72cjogxz 5530 5 CLE CLE NNP cord-015369-72cjogxz 5530 6 results result NNS cord-015369-72cjogxz 5530 7 from from IN cord-015369-72cjogxz 5530 8 refluxinduced refluxinduced JJ cord-015369-72cjogxz 5530 9 genetic genetic JJ cord-015369-72cjogxz 5530 10 changes change NNS cord-015369-72cjogxz 5530 11 within within IN cord-015369-72cjogxz 5530 12 the the DT cord-015369-72cjogxz 5530 13 stem stem NN cord-015369-72cjogxz 5530 14 cells cell NNS cord-015369-72cjogxz 5530 15 of of IN cord-015369-72cjogxz 5530 16 the the DT cord-015369-72cjogxz 5530 17 esophageal esophageal JJ cord-015369-72cjogxz 5530 18 epithelium epithelium NN cord-015369-72cjogxz 5530 19 inducing induce VBG cord-015369-72cjogxz 5530 20 the the DT cord-015369-72cjogxz 5530 21 switch switch NN cord-015369-72cjogxz 5530 22 from from IN cord-015369-72cjogxz 5530 23 squamous squamous JJ cord-015369-72cjogxz 5530 24 to to IN cord-015369-72cjogxz 5530 25 cardiac cardiac JJ cord-015369-72cjogxz 5530 26 mucosa mucosa JJ cord-015369-72cjogxz 5530 27 ( ( -LRB- cord-015369-72cjogxz 5530 28 CM CM NNP cord-015369-72cjogxz 5530 29 ) ) -RRB- cord-015369-72cjogxz 5530 30 mediated mediate VBN cord-015369-72cjogxz 5530 31 via via IN cord-015369-72cjogxz 5530 32 bone bone NN cord-015369-72cjogxz 5530 33 morphogenetic morphogenetic JJ cord-015369-72cjogxz 5530 34 protein protein NN cord-015369-72cjogxz 5530 35 4 4 CD cord-015369-72cjogxz 5530 36 . . . cord-015369-72cjogxz 5531 1 CM CM NNP cord-015369-72cjogxz 5531 2 may may MD cord-015369-72cjogxz 5531 3 progress progress VB cord-015369-72cjogxz 5531 4 towards towards IN cord-015369-72cjogxz 5531 5 oxyntocardiac oxyntocardiac NN cord-015369-72cjogxz 5531 6 mucosa mucosa JJ cord-015369-72cjogxz 5531 7 ( ( -LRB- cord-015369-72cjogxz 5531 8 OCM OCM NNP cord-015369-72cjogxz 5531 9 ) ) -RRB- cord-015369-72cjogxz 5531 10 by by IN cord-015369-72cjogxz 5531 11 inclusion inclusion NN cord-015369-72cjogxz 5531 12 of of IN cord-015369-72cjogxz 5531 13 parietal parietal JJ cord-015369-72cjogxz 5531 14 cells cell NNS cord-015369-72cjogxz 5531 15 ( ( -LRB- cord-015369-72cjogxz 5531 16 mediated mediate VBN cord-015369-72cjogxz 5531 17 via via IN cord-015369-72cjogxz 5531 18 sonic sonic JJ cord-015369-72cjogxz 5531 19 hedge hedge NN cord-015369-72cjogxz 5531 20 hog hog NN cord-015369-72cjogxz 5531 21 , , , cord-015369-72cjogxz 5531 22 SSH ssh NN cord-015369-72cjogxz 5531 23 , , , cord-015369-72cjogxz 5531 24 promoting promote VBG cord-015369-72cjogxz 5531 25 parietal parietal JJ cord-015369-72cjogxz 5531 26 cell cell NN cord-015369-72cjogxz 5531 27 maturation maturation NN cord-015369-72cjogxz 5531 28 ) ) -RRB- cord-015369-72cjogxz 5531 29 or or CC cord-015369-72cjogxz 5531 30 to to TO cord-015369-72cjogxz 5531 31 intestinal intestinal VB cord-015369-72cjogxz 5531 32 metaplasia metaplasia NN cord-015369-72cjogxz 5531 33 ( ( -LRB- cord-015369-72cjogxz 5531 34 IM im RB cord-015369-72cjogxz 5531 35 ¼ ¼ NNP cord-015369-72cjogxz 5531 36 Barrett Barrett NNP cord-015369-72cjogxz 5531 37 's 's POS cord-015369-72cjogxz 5531 38 esophagus esophagus NN cord-015369-72cjogxz 5531 39 ) ) -RRB- cord-015369-72cjogxz 5531 40 by by IN cord-015369-72cjogxz 5531 41 inclusion inclusion NN cord-015369-72cjogxz 5531 42 of of IN cord-015369-72cjogxz 5531 43 goblet goblet NN cord-015369-72cjogxz 5531 44 cells cell NNS cord-015369-72cjogxz 5531 45 ( ( -LRB- cord-015369-72cjogxz 5531 46 mediated mediate VBN cord-015369-72cjogxz 5531 47 via via IN cord-015369-72cjogxz 5531 48 Cdx2 Cdx2 NNP cord-015369-72cjogxz 5531 49 ) ) -RRB- cord-015369-72cjogxz 5531 50 . . . cord-015369-72cjogxz 5532 1 SHH SHH NNP cord-015369-72cjogxz 5532 2 and and CC cord-015369-72cjogxz 5532 3 Cdx2 Cdx2 NNP cord-015369-72cjogxz 5532 4 pathway pathway NN cord-015369-72cjogxz 5532 5 is be VBZ cord-015369-72cjogxz 5532 6 stimulated stimulate VBN cord-015369-72cjogxz 5532 7 by by IN cord-015369-72cjogxz 5532 8 acidic acidic JJ cord-015369-72cjogxz 5532 9 and and CC cord-015369-72cjogxz 5532 10 alkaline alkaline JJ cord-015369-72cjogxz 5532 11 pH ph NN cord-015369-72cjogxz 5532 12 , , , cord-015369-72cjogxz 5532 13 respectively respectively RB cord-015369-72cjogxz 5532 14 . . . cord-015369-72cjogxz 5533 1 Thus thus RB cord-015369-72cjogxz 5533 2 the the DT cord-015369-72cjogxz 5533 3 proximal proximal JJ cord-015369-72cjogxz 5533 4 location location NN cord-015369-72cjogxz 5533 5 of of IN cord-015369-72cjogxz 5533 6 intestinal intestinal JJ cord-015369-72cjogxz 5533 7 metaplasia metaplasia NN cord-015369-72cjogxz 5533 8 within within IN cord-015369-72cjogxz 5533 9 a a DT cord-015369-72cjogxz 5533 10 given give VBN cord-015369-72cjogxz 5533 11 CLE cle NN cord-015369-72cjogxz 5533 12 segment segment NN cord-015369-72cjogxz 5533 13 is be VBZ cord-015369-72cjogxz 5533 14 considered consider VBN cord-015369-72cjogxz 5533 15 to to TO cord-015369-72cjogxz 5533 16 reflect reflect VB cord-015369-72cjogxz 5533 17 the the DT cord-015369-72cjogxz 5533 18 pH pH NNP cord-015369-72cjogxz 5533 19 gradient gradient NN cord-015369-72cjogxz 5533 20 with with IN cord-015369-72cjogxz 5533 21 acidic acidic JJ cord-015369-72cjogxz 5533 22 and and CC cord-015369-72cjogxz 5533 23 alkaline alkaline JJ cord-015369-72cjogxz 5533 24 pH ph NN cord-015369-72cjogxz 5533 25 in in IN cord-015369-72cjogxz 5533 26 the the DT cord-015369-72cjogxz 5533 27 distal distal JJ cord-015369-72cjogxz 5533 28 and and CC cord-015369-72cjogxz 5533 29 proximal proximal JJ cord-015369-72cjogxz 5533 30 CLE CLE NNP cord-015369-72cjogxz 5533 31 segment segment NN cord-015369-72cjogxz 5533 32 , , , cord-015369-72cjogxz 5533 33 respectively respectively RB cord-015369-72cjogxz 5533 34 . . . cord-015369-72cjogxz 5534 1 While while IN cord-015369-72cjogxz 5534 2 SHH SHH NNP cord-015369-72cjogxz 5534 3 mediated mediate VBD cord-015369-72cjogxz 5534 4 OCM OCM NNP cord-015369-72cjogxz 5534 5 does do VBZ cord-015369-72cjogxz 5534 6 not not RB cord-015369-72cjogxz 5534 7 progress progress VB cord-015369-72cjogxz 5534 8 towards towards IN cord-015369-72cjogxz 5534 9 intestinal intestinal JJ cord-015369-72cjogxz 5534 10 metaplasia metaplasia NN cord-015369-72cjogxz 5534 11 and and CC cord-015369-72cjogxz 5534 12 cancer cancer NN cord-015369-72cjogxz 5534 13 , , , cord-015369-72cjogxz 5534 14 the the DT cord-015369-72cjogxz 5534 15 Cdx2 Cdx2 NNP cord-015369-72cjogxz 5534 16 pathway pathway NN cord-015369-72cjogxz 5534 17 favors favor VBZ cord-015369-72cjogxz 5534 18 progression progression NN cord-015369-72cjogxz 5534 19 of of IN cord-015369-72cjogxz 5534 20 intestinal intestinal JJ cord-015369-72cjogxz 5534 21 metaplasia metaplasia NN cord-015369-72cjogxz 5534 22 towards towards IN cord-015369-72cjogxz 5534 23 dysplasia dysplasia NN cord-015369-72cjogxz 5534 24 and and CC cord-015369-72cjogxz 5534 25 cancer cancer NN cord-015369-72cjogxz 5534 26 . . . cord-015369-72cjogxz 5535 1 Expression expression NN cord-015369-72cjogxz 5535 2 of of IN cord-015369-72cjogxz 5535 3 Cdx2 Cdx2 NNP cord-015369-72cjogxz 5535 4 within within IN cord-015369-72cjogxz 5535 5 CLE CLE NNP cord-015369-72cjogxz 5535 6 is be VBZ cord-015369-72cjogxz 5535 7 reduced reduce VBN cord-015369-72cjogxz 5535 8 to to TO cord-015369-72cjogxz 5535 9 control control VB cord-015369-72cjogxz 5535 10 values value NNS cord-015369-72cjogxz 5535 11 following follow VBG cord-015369-72cjogxz 5535 12 elimination elimination NN cord-015369-72cjogxz 5535 13 of of IN cord-015369-72cjogxz 5535 14 reflux reflux NN cord-015369-72cjogxz 5535 15 after after IN cord-015369-72cjogxz 5535 16 an an DT cord-015369-72cjogxz 5535 17 effective effective JJ cord-015369-72cjogxz 5535 18 anti anti JJ cord-015369-72cjogxz 5535 19 reflux reflux NN cord-015369-72cjogxz 5535 20 surgery surgery NN cord-015369-72cjogxz 5535 21 . . . cord-015369-72cjogxz 5536 1 Conclusions conclusion NNS cord-015369-72cjogxz 5536 2 . . . cord-015369-72cjogxz 5537 1 CLE CLE NNP cord-015369-72cjogxz 5537 2 results result VBZ cord-015369-72cjogxz 5537 3 from from IN cord-015369-72cjogxz 5537 4 milieu milieu NN cord-015369-72cjogxz 5537 5 - - HYPH cord-015369-72cjogxz 5537 6 dependent dependent JJ cord-015369-72cjogxz 5537 7 esophageal esophageal JJ cord-015369-72cjogxz 5537 8 epithelial epithelial JJ cord-015369-72cjogxz 5537 9 stem stem NN cord-015369-72cjogxz 5537 10 cell cell NN cord-015369-72cjogxz 5537 11 changes change NNS cord-015369-72cjogxz 5537 12 activated activate VBN cord-015369-72cjogxz 5537 13 during during IN cord-015369-72cjogxz 5537 14 gastroesophageal gastroesophageal JJ cord-015369-72cjogxz 5537 15 reflux reflux NN cord-015369-72cjogxz 5537 16 . . . cord-015369-72cjogxz 5538 1 These these DT cord-015369-72cjogxz 5538 2 findings finding NNS cord-015369-72cjogxz 5538 3 are be VBP cord-015369-72cjogxz 5538 4 suggested suggest VBN cord-015369-72cjogxz 5538 5 to to TO cord-015369-72cjogxz 5538 6 explain explain VB cord-015369-72cjogxz 5538 7 why why WRB cord-015369-72cjogxz 5538 8 antireflux antireflux NNP cord-015369-72cjogxz 5538 9 surgery surgery NN cord-015369-72cjogxz 5538 10 favors favor VBZ cord-015369-72cjogxz 5538 11 regression regression NN cord-015369-72cjogxz 5538 12 of of IN cord-015369-72cjogxz 5538 13 Barrett Barrett NNP cord-015369-72cjogxz 5538 14 's 's POS cord-015369-72cjogxz 5538 15 esophagus esophagus NN cord-015369-72cjogxz 5538 16 . . . cord-015369-72cjogxz 5539 1 Successful successful JJ cord-015369-72cjogxz 5539 2 interdisciplinary interdisciplinary JJ cord-015369-72cjogxz 5539 3 management management NN cord-015369-72cjogxz 5539 4 of of IN cord-015369-72cjogxz 5539 5 2 2 CD cord-015369-72cjogxz 5539 6 simultaneous simultaneous JJ cord-015369-72cjogxz 5539 7 mesenchymal mesenchymal JJ cord-015369-72cjogxz 5539 8 tumor tumor NN cord-015369-72cjogxz 5539 9 manifestations manifestation NNS cord-015369-72cjogxz 5539 10 with with IN cord-015369-72cjogxz 5539 11 synchronous synchronous JJ cord-015369-72cjogxz 5539 12 resectionrare resectionrare NN cord-015369-72cjogxz 5539 13 and and CC cord-015369-72cjogxz 5539 14 challenging challenging JJ cord-015369-72cjogxz 5539 15 combination combination NN cord-015369-72cjogxz 5539 16 of of IN cord-015369-72cjogxz 5539 17 a a DT cord-015369-72cjogxz 5539 18 gastric gastric JJ cord-015369-72cjogxz 5539 19 ' ' '' cord-015369-72cjogxz 5539 20 ' ' '' cord-015369-72cjogxz 5539 21 high high JJ cord-015369-72cjogxz 5539 22 - - HYPH cord-015369-72cjogxz 5539 23 risk risk NN cord-015369-72cjogxz 5539 24 ' ' '' cord-015369-72cjogxz 5539 25 ' ' '' cord-015369-72cjogxz 5539 26 GIST gist NN cord-015369-72cjogxz 5539 27 and and CC cord-015369-72cjogxz 5539 28 retroperitoneal retroperitoneal JJ cord-015369-72cjogxz 5539 29 liposarcoma liposarcoma NNP cord-015369-72cjogxz 5539 30 Methodik Methodik NNP cord-015369-72cjogxz 5539 31 . . . cord-015369-72cjogxz 5540 1 Anhand Anhand NNP cord-015369-72cjogxz 5540 2 eines eine NNS cord-015369-72cjogxz 5541 1 außergewöhnlichen außergewöhnlichen NNP cord-015369-72cjogxz 5541 2 exemplarischen exemplarischen NNP cord-015369-72cjogxz 5541 3 Fallberichtes Fallberichtes NNP cord-015369-72cjogxz 5541 4 wird wird NNP cord-015369-72cjogxz 5541 5 eine eine NNP cord-015369-72cjogxz 5542 1 47-jährige 47-jährige CD cord-015369-72cjogxz 5542 2 Patientin Patientin NNP cord-015369-72cjogxz 5542 3 mit mit NNP cord-015369-72cjogxz 5542 4 einem einem NNP cord-015369-72cjogxz 5542 5 GIST GIST NNP cord-015369-72cjogxz 5543 1 an an DT cord-015369-72cjogxz 5543 2 der der NN cord-015369-72cjogxz 5543 3 kleinen kleinen NNP cord-015369-72cjogxz 5543 4 Magenkurvatur Magenkurvatur NNP cord-015369-72cjogxz 5543 5 und und IN cord-015369-72cjogxz 5543 6 einem einem NNP cord-015369-72cjogxz 5543 7 monströsen monströsen NNP cord-015369-72cjogxz 5543 8 retroperitonealem retroperitonealem NNP cord-015369-72cjogxz 5544 1 Liposarkom Liposarkom NNP cord-015369-72cjogxz 5544 2 links link NNS cord-015369-72cjogxz 5544 3 - - : cord-015369-72cjogxz 5544 4 abdominal abdominal JJ cord-015369-72cjogxz 5544 5 mit mit NNP cord-015369-72cjogxz 5544 6 Infiltration Infiltration NNP cord-015369-72cjogxz 5544 7 der der NNP cord-015369-72cjogxz 5544 8 linken linken NNP cord-015369-72cjogxz 5544 9 Niere Niere NNP cord-015369-72cjogxz 5544 10 dargestellt dargestellt NNP cord-015369-72cjogxz 5544 11 . . . cord-015369-72cjogxz 5545 1 Der Der NNP cord-015369-72cjogxz 5545 2 GIST GIST NNP cord-015369-72cjogxz 5545 3 wurde wurde NN cord-015369-72cjogxz 5545 4 durch durch NNP cord-015369-72cjogxz 5545 5 eine eine NNP cord-015369-72cjogxz 5545 6 tangentiale tangentiale NN cord-015369-72cjogxz 5546 1 Magenwandteilresektion Magenwandteilresektion NNP cord-015369-72cjogxz 5546 2 und und IN cord-015369-72cjogxz 5546 3 das das NNP cord-015369-72cjogxz 5546 4 Liposarkom Liposarkom NNP cord-015369-72cjogxz 5546 5 in in IN cord-015369-72cjogxz 5546 6 toto toto NNP cord-015369-72cjogxz 5546 7 zusammen zusammen NNP cord-015369-72cjogxz 5546 8 mit mit NNP cord-015369-72cjogxz 5546 9 der der NNP cord-015369-72cjogxz 5546 10 linken linken NNP cord-015369-72cjogxz 5547 1 Niere Niere NNP cord-015369-72cjogxz 5547 2 aufgrund aufgrund NNP cord-015369-72cjogxz 5547 3 der der NNP cord-015369-72cjogxz 5547 4 Tumorinfiltration Tumorinfiltration NNP cord-015369-72cjogxz 5547 5 entfernt entfernt NNP cord-015369-72cjogxz 5547 6 . . . cord-015369-72cjogxz 5548 1 I -PRON- PRP cord-015369-72cjogxz 5548 2 m be VBP cord-015369-72cjogxz 5548 3 Anschluss Anschluss NNP cord-015369-72cjogxz 5548 4 folgte folgte IN cord-015369-72cjogxz 5548 5 eine eine NN cord-015369-72cjogxz 5548 6 kombinierte kombinierte NN cord-015369-72cjogxz 5548 7 Radiochemotherapie Radiochemotherapie NNP cord-015369-72cjogxz 5549 1 für für IN cord-015369-72cjogxz 5549 2 das das NNP cord-015369-72cjogxz 5549 3 Liposarkom Liposarkom NNP cord-015369-72cjogxz 5549 4 . . . cord-015369-72cjogxz 5550 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 5550 2 . . . cord-015369-72cjogxz 5551 1 Beide Beide NNP cord-015369-72cjogxz 5551 2 Tumoren Tumoren NNP cord-015369-72cjogxz 5551 3 wurden wurden VBD cord-015369-72cjogxz 5551 4 weitestgehend weitestgehend NN cord-015369-72cjogxz 5551 5 komplett komplett NNP cord-015369-72cjogxz 5551 6 entfernt entfernt NNP cord-015369-72cjogxz 5551 7 . . . cord-015369-72cjogxz 5552 1 Der Der NNP cord-015369-72cjogxz 5552 2 technisch technisch NNP cord-015369-72cjogxz 5552 3 schwierige schwierige NNP cord-015369-72cjogxz 5552 4 Eingriff Eingriff NNP cord-015369-72cjogxz 5552 5 sowie sowie NNP cord-015369-72cjogxz 5552 6 der der NNP cord-015369-72cjogxz 5552 7 postoperative postoperative JJ cord-015369-72cjogxz 5552 8 Verlauf Verlauf NNP cord-015369-72cjogxz 5552 9 gestalteten gestalteten NNP cord-015369-72cjogxz 5552 10 sich sich NNP cord-015369-72cjogxz 5552 11 komplikationslos komplikationslos NNP cord-015369-72cjogxz 5552 12 . . . cord-015369-72cjogxz 5553 1 Histologisch Histologisch NNP cord-015369-72cjogxz 5553 2 wurde wurde NN cord-015369-72cjogxz 5553 3 beim beim NNP cord-015369-72cjogxz 5553 4 Magenwandtumor Magenwandtumor NNP cord-015369-72cjogxz 5553 5 die die VBP cord-015369-72cjogxz 5553 6 R0-Resektion r0-resektion NN cord-015369-72cjogxz 5553 7 bestätigt bestätigt NNP cord-015369-72cjogxz 5553 8 und und NNP cord-015369-72cjogxz 5554 1 dieser dieser NNP cord-015369-72cjogxz 5554 2 aufgrund aufgrund NNP cord-015369-72cjogxz 5554 3 seiner seiner NNP cord-015369-72cjogxz 5555 1 Größe(6,5 größe(6,5 NN cord-015369-72cjogxz 5556 1 cm cm NNP cord-015369-72cjogxz 5556 2 Durchmesser Durchmesser NNP cord-015369-72cjogxz 5556 3 ) ) -RRB- cord-015369-72cjogxz 5557 1 und und NNP cord-015369-72cjogxz 5558 1 einer einer NNP cord-015369-72cjogxz 5558 2 mitotischen mitotischen NNP cord-015369-72cjogxz 5558 3 Aktivität(6 Aktivität(6 NNP cord-015369-72cjogxz 5558 4 Mitosen/50 Mitosen/50 NNP cord-015369-72cjogxz 5558 5 HPF HPF NNP cord-015369-72cjogxz 5558 6 ) ) -RRB- cord-015369-72cjogxz 5558 7 als als NNP cord-015369-72cjogxz 5558 8 , , , cord-015369-72cjogxz 5558 9 , , , cord-015369-72cjogxz 5558 10 high high RB cord-015369-72cjogxz 5558 11 - - HYPH cord-015369-72cjogxz 5558 12 risk''-GIST risk''-GIST NNP cord-015369-72cjogxz 5558 13 eingeordnet eingeordnet NN cord-015369-72cjogxz 5558 14 . . . cord-015369-72cjogxz 5559 1 Die die VB cord-015369-72cjogxz 5560 1 Neoplasie Neoplasie NNP cord-015369-72cjogxz 5560 2 des des FW cord-015369-72cjogxz 5560 3 linken linken NNP cord-015369-72cjogxz 5560 4 Retroperitoneums Retroperitoneums NNP cord-015369-72cjogxz 5560 5 wurde wurde NNP cord-015369-72cjogxz 5560 6 als als CD cord-015369-72cjogxz 5560 7 myofibroblastisch myofibroblastisch NNP cord-015369-72cjogxz 5560 8 - - HYPH cord-015369-72cjogxz 5560 9 dedifferenziertes dedifferenzierte NNS cord-015369-72cjogxz 5561 1 Liposarkom Liposarkom NNP cord-015369-72cjogxz 5561 2 ( ( -LRB- cord-015369-72cjogxz 5561 3 Grad Grad NNP cord-015369-72cjogxz 5561 4 2 2 CD cord-015369-72cjogxz 5561 5 nach nach NNP cord-015369-72cjogxz 5561 6 Coindre Coindre NNP cord-015369-72cjogxz 5561 7 ) ) -RRB- cord-015369-72cjogxz 5561 8 mit mit NNP cord-015369-72cjogxz 5561 9 dem dem NNP cord-015369-72cjogxz 5561 10 Tumorstadium Tumorstadium NNP cord-015369-72cjogxz 5561 11 pT2b pt2b NN cord-015369-72cjogxz 5561 12 G2 G2 NNP cord-015369-72cjogxz 5561 13 R1 R1 NNP cord-015369-72cjogxz 5562 1 i i PRP cord-015369-72cjogxz 5563 1 m m NNP cord-015369-72cjogxz 5563 2 Sinne Sinne NNP cord-015369-72cjogxz 5563 3 eines eine NNS cord-015369-72cjogxz 5564 1 unabhängigen unabhängigen NNP cord-015369-72cjogxz 5564 2 mesenchymalen mesenchymalen NNP cord-015369-72cjogxz 5564 3 Zweitmalignoms Zweitmalignoms NNP cord-015369-72cjogxz 5564 4 klassifiziert klassifiziert NN cord-015369-72cjogxz 5564 5 und und RB cord-015369-72cjogxz 5565 1 damit damit NNP cord-015369-72cjogxz 5565 2 ein ein NNP cord-015369-72cjogxz 5565 3 Metastasierungsgeschehen Metastasierungsgeschehen NNP cord-015369-72cjogxz 5565 4 ausschloss ausschloss NNP cord-015369-72cjogxz 5565 5 . . . cord-015369-72cjogxz 5566 1 Bei Bei NNP cord-015369-72cjogxz 5566 2 histologisch histologisch NNP cord-015369-72cjogxz 5566 3 gesicherter gesicherter NNP cord-015369-72cjogxz 5566 4 R1-Resektion R1-Resektion NNP cord-015369-72cjogxz 5566 5 des des NNP cord-015369-72cjogxz 5566 6 Liposarkoms Liposarkoms NNP cord-015369-72cjogxz 5566 7 erfolgten erfolgten NNP cord-015369-72cjogxz 5566 8 postoperativ postoperativ NNP cord-015369-72cjogxz 5566 9 eine eine NNP cord-015369-72cjogxz 5566 10 additive additive NN cord-015369-72cjogxz 5567 1 Radiochemotherapie Radiochemotherapie NNP cord-015369-72cjogxz 5567 2 nach nach NN cord-015369-72cjogxz 5567 3 VAIA VAIA NNP cord-015369-72cjogxz 5567 4 - - HYPH cord-015369-72cjogxz 5567 5 Protokoll Protokoll NNP cord-015369-72cjogxz 5567 6 ( ( -LRB- cord-015369-72cjogxz 5568 1 Adriamycin Adriamycin NNS cord-015369-72cjogxz 5568 2 , , , cord-015369-72cjogxz 5568 3 Ifosfamid Ifosfamid NNP cord-015369-72cjogxz 5568 4 , , , cord-015369-72cjogxz 5568 5 Vincristin Vincristin NNP cord-015369-72cjogxz 5568 6 ) ) -RRB- cord-015369-72cjogxz 5568 7 und und RB cord-015369-72cjogxz 5569 1 eine eine NNP cord-015369-72cjogxz 5569 2 Bestrahlung Bestrahlung NNP cord-015369-72cjogxz 5569 3 des des NNP cord-015369-72cjogxz 5569 4 retroperitonealen retroperitonealen NN cord-015369-72cjogxz 5570 1 Tumorbettes Tumorbettes NNP cord-015369-72cjogxz 5570 2 von von NNP cord-015369-72cjogxz 5570 3 46,6 46,6 CD cord-015369-72cjogxz 5570 4 Gy Gy NNP cord-015369-72cjogxz 5570 5 Gesamtdosis Gesamtdosis NNP cord-015369-72cjogxz 5570 6 . . . cord-015369-72cjogxz 5571 1 In in IN cord-015369-72cjogxz 5571 2 der der NN cord-015369-72cjogxz 5571 3 radioonkologischen radioonkologischen NNP cord-015369-72cjogxz 5572 1 Verlaufskontrolle Verlaufskontrolle NNP cord-015369-72cjogxz 5572 2 nach nach NNP cord-015369-72cjogxz 5572 3 6 6 CD cord-015369-72cjogxz 5572 4 Jahren Jahren NNP cord-015369-72cjogxz 5572 5 zeigte zeigte NNP cord-015369-72cjogxz 5572 6 sich sich NNP cord-015369-72cjogxz 5572 7 kein kein NNP cord-015369-72cjogxz 5572 8 Anhalt Anhalt NNP cord-015369-72cjogxz 5572 9 für für IN cord-015369-72cjogxz 5572 10 ein ein NNP cord-015369-72cjogxz 5572 11 Tumorrezidiv Tumorrezidiv NNP cord-015369-72cjogxz 5572 12 . . . cord-015369-72cjogxz 5573 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 5573 2 . . . cord-015369-72cjogxz 5574 1 Die die VB cord-015369-72cjogxz 5574 2 komplette komplette NNP cord-015369-72cjogxz 5574 3 Tumorresektion Tumorresektion NNP cord-015369-72cjogxz 5574 4 stellt stellt NNP cord-015369-72cjogxz 5574 5 die die VBP cord-015369-72cjogxz 5574 6 Therapie Therapie NNP cord-015369-72cjogxz 5574 7 der der NNP cord-015369-72cjogxz 5574 8 Wahl Wahl NNP cord-015369-72cjogxz 5574 9 bei bei NNP cord-015369-72cjogxz 5574 10 mesenchymalen mesenchymalen NNP cord-015369-72cjogxz 5575 1 Tumoren Tumoren NNP cord-015369-72cjogxz 5575 2 dar dar NNP cord-015369-72cjogxz 5575 3 ( ( -LRB- cord-015369-72cjogxz 5575 4 Ziel Ziel NNP cord-015369-72cjogxz 5575 5 : : : cord-015369-72cjogxz 5575 6 R0 R0 NNP cord-015369-72cjogxz 5575 7 ) ) -RRB- cord-015369-72cjogxz 5575 8 . . . cord-015369-72cjogxz 5576 1 Je Je NNP cord-015369-72cjogxz 5576 2 nach nach NNP cord-015369-72cjogxz 5576 3 histologischer histologischer NNP cord-015369-72cjogxz 5576 4 Tumorklassifikation Tumorklassifikation NNP cord-015369-72cjogxz 5576 5 und und NNP cord-015369-72cjogxz 5576 6 -sensitivität -sensitivität CD cord-015369-72cjogxz 5576 7 bzw bzw NNP cord-015369-72cjogxz 5576 8 . . . cord-015369-72cjogxz 5577 1 Resektionsstatus Resektionsstatus NNP cord-015369-72cjogxz 5577 2 ist ist FW cord-015369-72cjogxz 5577 3 eine eine NNP cord-015369-72cjogxz 5577 4 nachfolgende nachfolgende FW cord-015369-72cjogxz 5577 5 Radiatio Radiatio NNP cord-015369-72cjogxz 5577 6 und und XX cord-015369-72cjogxz 5578 1 oder oder NNP cord-015369-72cjogxz 5578 2 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 5578 3 erforderlich erforderlich NNP cord-015369-72cjogxz 5578 4 , , , cord-015369-72cjogxz 5578 5 was be VBD cord-015369-72cjogxz 5578 6 i -PRON- PRP cord-015369-72cjogxz 5578 7 m be VBP cord-015369-72cjogxz 5578 8 vorliegenden vorliegenden NNP cord-015369-72cjogxz 5578 9 Fall Fall NNP cord-015369-72cjogxz 5578 10 trotz trotz NNP cord-015369-72cjogxz 5578 11 R1-Resektion R1-Resektion NNP cord-015369-72cjogxz 5578 12 des des NNP cord-015369-72cjogxz 5578 13 Liposarkoms Liposarkoms NNP cord-015369-72cjogxz 5578 14 und und IN cord-015369-72cjogxz 5578 15 , , , cord-015369-72cjogxz 5578 16 , , , cord-015369-72cjogxz 5578 17 high high JJ cord-015369-72cjogxz 5578 18 risk''-GIST risk''-GIST NNP cord-015369-72cjogxz 5578 19 eine eine NNP cord-015369-72cjogxz 5578 20 bisher bisher NNP cord-015369-72cjogxz 5579 1 6jährige 6jährige CD cord-015369-72cjogxz 5579 2 tumorfreie tumorfreie NNP cord-015369-72cjogxz 5579 3 Ü Ü NNP cord-015369-72cjogxz 5579 4 berlebenszeit berlebenszeit NNP cord-015369-72cjogxz 5579 5 ermöglichte ermöglichte NNP cord-015369-72cjogxz 5579 6 . . . cord-015369-72cjogxz 5580 1 Schlüsselwörter Schlüsselwörter NNP cord-015369-72cjogxz 5580 2 . . . cord-015369-72cjogxz 5581 1 GIST GIST NNP cord-015369-72cjogxz 5581 2 , , , cord-015369-72cjogxz 5581 3 Liposarkom Liposarkom NNP cord-015369-72cjogxz 5581 4 , , , cord-015369-72cjogxz 5581 5 Radiatio Radiatio NNP cord-015369-72cjogxz 5581 6 , , , cord-015369-72cjogxz 5581 7 VAIA VAIA NNP cord-015369-72cjogxz 5581 8 - - HYPH cord-015369-72cjogxz 5581 9 Protokoll Protokoll NNP cord-015369-72cjogxz 5581 10 . . . cord-015369-72cjogxz 5582 1 Surgical surgical JJ cord-015369-72cjogxz 5582 2 aspects aspect NNS cord-015369-72cjogxz 5582 3 of of IN cord-015369-72cjogxz 5582 4 pneumatosis pneumatosis NN cord-015369-72cjogxz 5582 5 cystoides cystoides NNP cord-015369-72cjogxz 5582 6 intestinalis intestinalis NNP cord-015369-72cjogxz 5582 7 : : : cord-015369-72cjogxz 5583 1 report report NN cord-015369-72cjogxz 5583 2 of of IN cord-015369-72cjogxz 5583 3 two two CD cord-015369-72cjogxz 5583 4 cases case NNS cord-015369-72cjogxz 5583 5 E. E. NNP cord-015369-72cjogxz 5583 6 Schröpfer Schröpfer NNP cord-015369-72cjogxz 5583 7 , , , cord-015369-72cjogxz 5583 8 L. L. NNP cord-015369-72cjogxz 5583 9 Scheele Scheele NNP cord-015369-72cjogxz 5583 10 , , , cord-015369-72cjogxz 5583 11 C. C. NNP cord-015369-72cjogxz 5583 12 Wichelmann Wichelmann NNP cord-015369-72cjogxz 5583 13 , , , cord-015369-72cjogxz 5583 14 C. C. NNP cord-015369-72cjogxz 5583 15 T. T. NNP cord-015369-72cjogxz 5583 16 Germer Germer NNP cord-015369-72cjogxz 5583 17 , , , cord-015369-72cjogxz 5584 1 T. T. NNP cord-015369-72cjogxz 5584 2 Meyer Meyer NNP cord-015369-72cjogxz 5584 3 Univ.-Klinik Univ.-Klinik NNP cord-015369-72cjogxz 5584 4 Würzburg Würzburg NNP cord-015369-72cjogxz 5584 5 , , , cord-015369-72cjogxz 5584 6 Würzburg Würzburg NNP cord-015369-72cjogxz 5584 7 , , , cord-015369-72cjogxz 5585 1 Germany Germany NNP cord-015369-72cjogxz 5585 2 Pneumatosis Pneumatosis NNP cord-015369-72cjogxz 5585 3 cystoides cystoide VBZ cord-015369-72cjogxz 5585 4 intestinalis intestinalis NNP cord-015369-72cjogxz 5585 5 ( ( -LRB- cord-015369-72cjogxz 5585 6 PCI PCI NNP cord-015369-72cjogxz 5585 7 ) ) -RRB- cord-015369-72cjogxz 5585 8 is be VBZ cord-015369-72cjogxz 5585 9 a a DT cord-015369-72cjogxz 5585 10 rare rare JJ cord-015369-72cjogxz 5585 11 disease disease NN cord-015369-72cjogxz 5585 12 usually usually RB cord-015369-72cjogxz 5585 13 caused cause VBN cord-015369-72cjogxz 5585 14 by by IN cord-015369-72cjogxz 5585 15 an an DT cord-015369-72cjogxz 5585 16 underlying underlying JJ cord-015369-72cjogxz 5585 17 condition condition NN cord-015369-72cjogxz 5585 18 . . . cord-015369-72cjogxz 5586 1 It -PRON- PRP cord-015369-72cjogxz 5586 2 is be VBZ cord-015369-72cjogxz 5586 3 defined define VBN cord-015369-72cjogxz 5586 4 as as IN cord-015369-72cjogxz 5586 5 air air NN cord-015369-72cjogxz 5586 6 filled fill VBN cord-015369-72cjogxz 5586 7 cysts cyst NNS cord-015369-72cjogxz 5586 8 within within IN cord-015369-72cjogxz 5586 9 the the DT cord-015369-72cjogxz 5586 10 wall wall NN cord-015369-72cjogxz 5586 11 of of IN cord-015369-72cjogxz 5586 12 the the DT cord-015369-72cjogxz 5586 13 gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 5586 14 tract tract NN cord-015369-72cjogxz 5586 15 . . . cord-015369-72cjogxz 5587 1 The the DT cord-015369-72cjogxz 5587 2 true true JJ cord-015369-72cjogxz 5587 3 incidence incidence NN cord-015369-72cjogxz 5587 4 is be VBZ cord-015369-72cjogxz 5587 5 unknown unknown JJ cord-015369-72cjogxz 5587 6 , , , cord-015369-72cjogxz 5587 7 PCI PCI NNP cord-015369-72cjogxz 5587 8 is be VBZ cord-015369-72cjogxz 5587 9 often often RB cord-015369-72cjogxz 5587 10 an an DT cord-015369-72cjogxz 5587 11 incidental incidental JJ cord-015369-72cjogxz 5587 12 finding finding NN cord-015369-72cjogxz 5587 13 on on IN cord-015369-72cjogxz 5587 14 radiographs radiograph NNS cord-015369-72cjogxz 5587 15 . . . cord-015369-72cjogxz 5588 1 We -PRON- PRP cord-015369-72cjogxz 5588 2 report report VBP cord-015369-72cjogxz 5588 3 on on IN cord-015369-72cjogxz 5588 4 two two CD cord-015369-72cjogxz 5588 5 different different JJ cord-015369-72cjogxz 5588 6 cases case NNS cord-015369-72cjogxz 5588 7 of of IN cord-015369-72cjogxz 5588 8 pneumatosis pneumatosis NN cord-015369-72cjogxz 5588 9 cystoides cystoides NNP cord-015369-72cjogxz 5588 10 intestinalis intestinalis NNP cord-015369-72cjogxz 5588 11 . . . cord-015369-72cjogxz 5589 1 Both both DT cord-015369-72cjogxz 5589 2 patients patient NNS cord-015369-72cjogxz 5589 3 underwent undergo VBD cord-015369-72cjogxz 5589 4 surgical surgical JJ cord-015369-72cjogxz 5589 5 treatment treatment NN cord-015369-72cjogxz 5589 6 in in IN cord-015369-72cjogxz 5589 7 our -PRON- PRP$ cord-015369-72cjogxz 5589 8 department department NN cord-015369-72cjogxz 5589 9 . . . cord-015369-72cjogxz 5590 1 The the DT cord-015369-72cjogxz 5590 2 first first JJ cord-015369-72cjogxz 5590 3 patient patient NN cord-015369-72cjogxz 5590 4 , , , cord-015369-72cjogxz 5590 5 a a DT cord-015369-72cjogxz 5590 6 17 17 CD cord-015369-72cjogxz 5590 7 year year NN cord-015369-72cjogxz 5590 8 old old JJ cord-015369-72cjogxz 5590 9 white white JJ cord-015369-72cjogxz 5590 10 European european JJ cord-015369-72cjogxz 5590 11 girl girl NN cord-015369-72cjogxz 5590 12 , , , cord-015369-72cjogxz 5590 13 with with IN cord-015369-72cjogxz 5590 14 Down Down NNP cord-015369-72cjogxz 5590 15 syndrome syndrome NN cord-015369-72cjogxz 5590 16 and and CC cord-015369-72cjogxz 5590 17 leucopenia leucopenia NNP cord-015369-72cjogxz 5590 18 due due JJ cord-015369-72cjogxz 5590 19 to to IN cord-015369-72cjogxz 5590 20 chemotherapy chemotherapy NN cord-015369-72cjogxz 5590 21 for for IN cord-015369-72cjogxz 5590 22 acute acute JJ cord-015369-72cjogxz 5590 23 lymphatic lymphatic JJ cord-015369-72cjogxz 5590 24 leukemia leukemia NN cord-015369-72cjogxz 5590 25 was be VBD cord-015369-72cjogxz 5590 26 admitted admit VBN cord-015369-72cjogxz 5590 27 to to IN cord-015369-72cjogxz 5590 28 our -PRON- PRP$ cord-015369-72cjogxz 5590 29 surgical surgical JJ cord-015369-72cjogxz 5590 30 department department NN cord-015369-72cjogxz 5590 31 with with IN cord-015369-72cjogxz 5590 32 acute acute JJ cord-015369-72cjogxz 5590 33 septic septic JJ cord-015369-72cjogxz 5590 34 conditions condition NNS cord-015369-72cjogxz 5590 35 and and CC cord-015369-72cjogxz 5590 36 air air NN cord-015369-72cjogxz 5590 37 filled fill VBN cord-015369-72cjogxz 5590 38 cysts cyst NNS cord-015369-72cjogxz 5590 39 in in IN cord-015369-72cjogxz 5590 40 the the DT cord-015369-72cjogxz 5590 41 intestine intestine NN cord-015369-72cjogxz 5590 42 wall wall NN cord-015369-72cjogxz 5590 43 . . . cord-015369-72cjogxz 5591 1 Explorative explorative JJ cord-015369-72cjogxz 5591 2 laparotomy laparotomy NN cord-015369-72cjogxz 5591 3 revealed reveal VBD cord-015369-72cjogxz 5591 4 acute acute JJ cord-015369-72cjogxz 5591 5 ischemia ischemia NN cord-015369-72cjogxz 5591 6 of of IN cord-015369-72cjogxz 5591 7 the the DT cord-015369-72cjogxz 5591 8 right right JJ cord-015369-72cjogxz 5591 9 colon colon NN cord-015369-72cjogxz 5591 10 and and CC cord-015369-72cjogxz 5591 11 resection resection NN cord-015369-72cjogxz 5591 12 of of IN cord-015369-72cjogxz 5591 13 the the DT cord-015369-72cjogxz 5591 14 affected affect VBN cord-015369-72cjogxz 5591 15 intestine intestine NN cord-015369-72cjogxz 5591 16 was be VBD cord-015369-72cjogxz 5591 17 performed perform VBN cord-015369-72cjogxz 5591 18 . . . cord-015369-72cjogxz 5592 1 After after IN cord-015369-72cjogxz 5592 2 a a DT cord-015369-72cjogxz 5592 3 short short JJ cord-015369-72cjogxz 5592 4 interval interval NN cord-015369-72cjogxz 5592 5 in in IN cord-015369-72cjogxz 5592 6 the the DT cord-015369-72cjogxz 5592 7 intensive intensive JJ cord-015369-72cjogxz 5592 8 care care NN cord-015369-72cjogxz 5592 9 unit unit NN cord-015369-72cjogxz 5592 10 the the DT cord-015369-72cjogxz 5592 11 patient patient NN cord-015369-72cjogxz 5592 12 was be VBD cord-015369-72cjogxz 5592 13 referred refer VBN cord-015369-72cjogxz 5592 14 to to IN cord-015369-72cjogxz 5592 15 the the DT cord-015369-72cjogxz 5592 16 pediatric pediatric JJ cord-015369-72cjogxz 5592 17 department department NN cord-015369-72cjogxz 5592 18 . . . cord-015369-72cjogxz 5593 1 The the DT cord-015369-72cjogxz 5593 2 second second JJ cord-015369-72cjogxz 5593 3 patient patient NN cord-015369-72cjogxz 5593 4 , , , cord-015369-72cjogxz 5593 5 a a DT cord-015369-72cjogxz 5593 6 79-year 79-year JJ cord-015369-72cjogxz 5593 7 old old JJ cord-015369-72cjogxz 5593 8 , , , cord-015369-72cjogxz 5593 9 white white JJ cord-015369-72cjogxz 5593 10 European european JJ cord-015369-72cjogxz 5593 11 man man NN cord-015369-72cjogxz 5593 12 with with IN cord-015369-72cjogxz 5593 13 urothelial urothelial JJ cord-015369-72cjogxz 5593 14 carcinoma carcinoma NN cord-015369-72cjogxz 5593 15 of of IN cord-015369-72cjogxz 5593 16 the the DT cord-015369-72cjogxz 5593 17 bladder bladder NN cord-015369-72cjogxz 5593 18 and and CC cord-015369-72cjogxz 5593 19 carcinoma carcinoma NN cord-015369-72cjogxz 5593 20 of of IN cord-015369-72cjogxz 5593 21 the the DT cord-015369-72cjogxz 5593 22 prostate prostate NN cord-015369-72cjogxz 5593 23 underwent undergo VBD cord-015369-72cjogxz 5593 24 radical radical JJ cord-015369-72cjogxz 5593 25 cysto cysto NN cord-015369-72cjogxz 5593 26 - - HYPH cord-015369-72cjogxz 5593 27 prostatectomy prostatectomy NN cord-015369-72cjogxz 5593 28 in in IN cord-015369-72cjogxz 5593 29 the the DT cord-015369-72cjogxz 5593 30 department department NNP cord-015369-72cjogxz 5593 31 of of IN cord-015369-72cjogxz 5593 32 urology urology NNP cord-015369-72cjogxz 5593 33 . . . cord-015369-72cjogxz 5594 1 After after IN cord-015369-72cjogxz 5594 2 several several JJ cord-015369-72cjogxz 5594 3 operations operation NNS cord-015369-72cjogxz 5594 4 due due JJ cord-015369-72cjogxz 5594 5 to to IN cord-015369-72cjogxz 5594 6 obstruction obstruction NN cord-015369-72cjogxz 5594 7 of of IN cord-015369-72cjogxz 5594 8 the the DT cord-015369-72cjogxz 5594 9 right right JJ cord-015369-72cjogxz 5594 10 common common JJ cord-015369-72cjogxz 5594 11 iliac iliac NN cord-015369-72cjogxz 5594 12 artery artery NN cord-015369-72cjogxz 5594 13 the the DT cord-015369-72cjogxz 5594 14 patient patient NN cord-015369-72cjogxz 5594 15 presented present VBD cord-015369-72cjogxz 5594 16 an an DT cord-015369-72cjogxz 5594 17 acute acute JJ cord-015369-72cjogxz 5594 18 abdomen abdomen NN cord-015369-72cjogxz 5594 19 and and CC cord-015369-72cjogxz 5594 20 computer computer NN cord-015369-72cjogxz 5594 21 tomography tomography NN cord-015369-72cjogxz 5594 22 revealed reveal VBD cord-015369-72cjogxz 5594 23 pneumatosis pneumatosis NNP cord-015369-72cjogxz 5594 24 intestinalis intestinalis NNP cord-015369-72cjogxz 5594 25 and and CC cord-015369-72cjogxz 5594 26 ileus ileus NNP cord-015369-72cjogxz 5594 27 of of IN cord-015369-72cjogxz 5594 28 the the DT cord-015369-72cjogxz 5594 29 colon colon NN cord-015369-72cjogxz 5594 30 . . . cord-015369-72cjogxz 5595 1 Only only RB cord-015369-72cjogxz 5595 2 adhesiolysis adhesiolysis NNP cord-015369-72cjogxz 5595 3 was be VBD cord-015369-72cjogxz 5595 4 performed perform VBN cord-015369-72cjogxz 5595 5 and and CC cord-015369-72cjogxz 5595 6 the the DT cord-015369-72cjogxz 5595 7 patient patient NN cord-015369-72cjogxz 5595 8 was be VBD cord-015369-72cjogxz 5595 9 discharged discharge VBN cord-015369-72cjogxz 5595 10 into into IN cord-015369-72cjogxz 5595 11 rehabilitation rehabilitation NN cord-015369-72cjogxz 5595 12 a a DT cord-015369-72cjogxz 5595 13 few few JJ cord-015369-72cjogxz 5595 14 weeks week NNS cord-015369-72cjogxz 5595 15 after after RB cord-015369-72cjogxz 5595 16 . . . cord-015369-72cjogxz 5596 1 Patients patient NNS cord-015369-72cjogxz 5596 2 with with IN cord-015369-72cjogxz 5596 3 the the DT cord-015369-72cjogxz 5596 4 radiographic radiographic JJ cord-015369-72cjogxz 5596 5 diagnosis diagnosis NN cord-015369-72cjogxz 5596 6 of of IN cord-015369-72cjogxz 5596 7 PCI PCI NNP cord-015369-72cjogxz 5596 8 should should MD cord-015369-72cjogxz 5596 9 receive receive VB cord-015369-72cjogxz 5596 10 a a DT cord-015369-72cjogxz 5596 11 thorough thorough JJ cord-015369-72cjogxz 5596 12 history history NN cord-015369-72cjogxz 5596 13 and and CC cord-015369-72cjogxz 5596 14 physical physical JJ cord-015369-72cjogxz 5596 15 examination examination NN cord-015369-72cjogxz 5596 16 . . . cord-015369-72cjogxz 5597 1 We -PRON- PRP cord-015369-72cjogxz 5597 2 discuss discuss VBP cord-015369-72cjogxz 5597 3 the the DT cord-015369-72cjogxz 5597 4 surgical surgical JJ cord-015369-72cjogxz 5597 5 management management NN cord-015369-72cjogxz 5597 6 of of IN cord-015369-72cjogxz 5597 7 PCI PCI NNP cord-015369-72cjogxz 5597 8 according accord VBG cord-015369-72cjogxz 5597 9 to to IN cord-015369-72cjogxz 5597 10 literature literature NN cord-015369-72cjogxz 5597 11 and and CC cord-015369-72cjogxz 5597 12 developed develop VBD cord-015369-72cjogxz 5597 13 an an DT cord-015369-72cjogxz 5597 14 algorithm algorithm NN cord-015369-72cjogxz 5597 15 . . . cord-015369-72cjogxz 5598 1 GastroIntestinale GastroIntestinale NNP cord-015369-72cjogxz 5598 2 Stromatumore Stromatumore NNP cord-015369-72cjogxz 5598 3 ( ( -LRB- cord-015369-72cjogxz 5598 4 GIST GIST NNP cord-015369-72cjogxz 5598 5 ) ) -RRB- cord-015369-72cjogxz 5598 6 : : : cord-015369-72cjogxz 5599 1 Modifizierte Modifizierte NNP cord-015369-72cjogxz 5599 2 therapeutische therapeutische IN cord-015369-72cjogxz 5599 3 Strategien Strategien NNP cord-015369-72cjogxz 5600 1 durch durch NNP cord-015369-72cjogxz 5600 2 PET PET NNP cord-015369-72cjogxz 5600 3 / / SYM cord-015369-72cjogxz 5600 4 CT CT NNP cord-015369-72cjogxz 5600 5 Background Background NNP cord-015369-72cjogxz 5600 6 . . . cord-015369-72cjogxz 5601 1 The the DT cord-015369-72cjogxz 5601 2 liver liver NN cord-015369-72cjogxz 5601 3 is be VBZ cord-015369-72cjogxz 5601 4 a a DT cord-015369-72cjogxz 5601 5 frequent frequent JJ cord-015369-72cjogxz 5601 6 site site NN cord-015369-72cjogxz 5601 7 for for IN cord-015369-72cjogxz 5601 8 metastases metastasis NNS cord-015369-72cjogxz 5601 9 of of IN cord-015369-72cjogxz 5601 10 colorectal colorectal JJ cord-015369-72cjogxz 5601 11 cancer cancer NN cord-015369-72cjogxz 5601 12 . . . cord-015369-72cjogxz 5602 1 Due due IN cord-015369-72cjogxz 5602 2 to to IN cord-015369-72cjogxz 5602 3 new new JJ cord-015369-72cjogxz 5602 4 chemotherapy chemotherapy NN cord-015369-72cjogxz 5602 5 agents agent NNS cord-015369-72cjogxz 5602 6 , , , cord-015369-72cjogxz 5602 7 strategies strategy NNS cord-015369-72cjogxz 5602 8 and and CC cord-015369-72cjogxz 5602 9 targeted target VBN cord-015369-72cjogxz 5602 10 agents agent NNS cord-015369-72cjogxz 5602 11 response response NN cord-015369-72cjogxz 5602 12 rates rate NNS cord-015369-72cjogxz 5602 13 and and CC cord-015369-72cjogxz 5602 14 respectability respectability NN cord-015369-72cjogxz 5602 15 rates rate NNS cord-015369-72cjogxz 5602 16 have have VBP cord-015369-72cjogxz 5602 17 improved improve VBN cord-015369-72cjogxz 5602 18 . . . cord-015369-72cjogxz 5603 1 Moreover moreover RB cord-015369-72cjogxz 5603 2 , , , cord-015369-72cjogxz 5603 3 some some DT cord-015369-72cjogxz 5603 4 patients patient NNS cord-015369-72cjogxz 5603 5 with with IN cord-015369-72cjogxz 5603 6 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 5603 7 chemotherapy chemotherapy NN cord-015369-72cjogxz 5603 8 have have VBP cord-015369-72cjogxz 5603 9 complete complete JJ cord-015369-72cjogxz 5603 10 response response NN cord-015369-72cjogxz 5603 11 of of IN cord-015369-72cjogxz 5603 12 the the DT cord-015369-72cjogxz 5603 13 liver liver NN cord-015369-72cjogxz 5603 14 tumors tumor NNS cord-015369-72cjogxz 5603 15 and and CC cord-015369-72cjogxz 5603 16 the the DT cord-015369-72cjogxz 5603 17 lesions lesion NNS cord-015369-72cjogxz 5603 18 are be VBP cord-015369-72cjogxz 5603 19 no no RB cord-015369-72cjogxz 5603 20 longer long RBR cord-015369-72cjogxz 5603 21 visible visible JJ cord-015369-72cjogxz 5603 22 by by IN cord-015369-72cjogxz 5603 23 preoperative preoperative JJ cord-015369-72cjogxz 5603 24 CT CT NNP cord-015369-72cjogxz 5603 25 - - HYPH cord-015369-72cjogxz 5603 26 scan scan NN cord-015369-72cjogxz 5603 27 or or CC cord-015369-72cjogxz 5603 28 intraoperatively intraoperatively NN cord-015369-72cjogxz 5603 29 . . . cord-015369-72cjogxz 5604 1 Methods method NNS cord-015369-72cjogxz 5604 2 . . . cord-015369-72cjogxz 5605 1 We -PRON- PRP cord-015369-72cjogxz 5605 2 report report VBP cord-015369-72cjogxz 5605 3 a a DT cord-015369-72cjogxz 5605 4 case case NN cord-015369-72cjogxz 5605 5 of of IN cord-015369-72cjogxz 5605 6 a a DT cord-015369-72cjogxz 5605 7 50 50 CD cord-015369-72cjogxz 5605 8 years year NNS cord-015369-72cjogxz 5605 9 old old JJ cord-015369-72cjogxz 5605 10 female female NN cord-015369-72cjogxz 5605 11 who who WP cord-015369-72cjogxz 5605 12 underwent undergo VBD cord-015369-72cjogxz 5605 13 right right JJ cord-015369-72cjogxz 5605 14 hemicolectomy hemicolectomy NN cord-015369-72cjogxz 5605 15 for for IN cord-015369-72cjogxz 5605 16 caecal caecal JJ cord-015369-72cjogxz 5605 17 cancer cancer NN cord-015369-72cjogxz 5605 18 in in IN cord-015369-72cjogxz 5605 19 an an DT cord-015369-72cjogxz 5605 20 outside outside JJ cord-015369-72cjogxz 5605 21 hospital hospital NN cord-015369-72cjogxz 5605 22 . . . cord-015369-72cjogxz 5606 1 Owing owe VBG cord-015369-72cjogxz 5606 2 to to IN cord-015369-72cjogxz 5606 3 synchronous synchronous JJ cord-015369-72cjogxz 5606 4 liver liver NN cord-015369-72cjogxz 5606 5 metastasis metastasis NN cord-015369-72cjogxz 5606 6 in in IN cord-015369-72cjogxz 5606 7 segment segment NN cord-015369-72cjogxz 5606 8 IV IV NNP cord-015369-72cjogxz 5606 9 b b NNP cord-015369-72cjogxz 5606 10 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 5606 11 chemotherapy chemotherapy NN cord-015369-72cjogxz 5606 12 was be VBD cord-015369-72cjogxz 5606 13 administered administer VBN cord-015369-72cjogxz 5606 14 . . . cord-015369-72cjogxz 5607 1 Follow follow VB cord-015369-72cjogxz 5607 2 - - HYPH cord-015369-72cjogxz 5607 3 up up RP cord-015369-72cjogxz 5607 4 CTscan CTscan NNP cord-015369-72cjogxz 5607 5 revealed reveal VBD cord-015369-72cjogxz 5607 6 complete complete JJ cord-015369-72cjogxz 5607 7 response response NN cord-015369-72cjogxz 5607 8 and and CC cord-015369-72cjogxz 5607 9 no no DT cord-015369-72cjogxz 5607 10 tumor tumor NN cord-015369-72cjogxz 5607 11 was be VBD cord-015369-72cjogxz 5607 12 visible visible JJ cord-015369-72cjogxz 5607 13 in in IN cord-015369-72cjogxz 5607 14 the the DT cord-015369-72cjogxz 5607 15 liver liver NN cord-015369-72cjogxz 5607 16 . . . cord-015369-72cjogxz 5608 1 Patient Patient NNP cord-015369-72cjogxz 5608 2 was be VBD cord-015369-72cjogxz 5608 3 then then RB cord-015369-72cjogxz 5608 4 referred refer VBN cord-015369-72cjogxz 5608 5 to to IN cord-015369-72cjogxz 5608 6 our -PRON- PRP$ cord-015369-72cjogxz 5608 7 center center NN cord-015369-72cjogxz 5608 8 for for IN cord-015369-72cjogxz 5608 9 further further JJ cord-015369-72cjogxz 5608 10 investigations investigation NNS cord-015369-72cjogxz 5608 11 . . . cord-015369-72cjogxz 5609 1 Results result NNS cord-015369-72cjogxz 5609 2 . . . cord-015369-72cjogxz 5610 1 CT CT NNP cord-015369-72cjogxz 5610 2 - - HYPH cord-015369-72cjogxz 5610 3 scan scan NNP cord-015369-72cjogxz 5610 4 and and CC cord-015369-72cjogxz 5610 5 MRI MRI NNP cord-015369-72cjogxz 5610 6 showed show VBD cord-015369-72cjogxz 5610 7 no no DT cord-015369-72cjogxz 5610 8 visible visible JJ cord-015369-72cjogxz 5610 9 tumor tumor NN cord-015369-72cjogxz 5610 10 . . . cord-015369-72cjogxz 5611 1 With with IN cord-015369-72cjogxz 5611 2 the the DT cord-015369-72cjogxz 5611 3 aid aid NN cord-015369-72cjogxz 5611 4 of of IN cord-015369-72cjogxz 5611 5 the the DT cord-015369-72cjogxz 5611 6 CT CT NNP cord-015369-72cjogxz 5611 7 - - HYPH cord-015369-72cjogxz 5611 8 scan scan NN cord-015369-72cjogxz 5611 9 before before IN cord-015369-72cjogxz 5611 10 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 5611 11 chemotherapy chemotherapy NN cord-015369-72cjogxz 5611 12 the the DT cord-015369-72cjogxz 5611 13 tumor tumor NN cord-015369-72cjogxz 5611 14 was be VBD cord-015369-72cjogxz 5611 15 measured measure VBN cord-015369-72cjogxz 5611 16 out out RP cord-015369-72cjogxz 5611 17 and and CC cord-015369-72cjogxz 5611 18 preoperatively preoperatively RB cord-015369-72cjogxz 5611 19 a a DT cord-015369-72cjogxz 5611 20 CT CT NNP cord-015369-72cjogxz 5611 21 - - HYPH cord-015369-72cjogxz 5611 22 guided guide VBN cord-015369-72cjogxz 5611 23 hook hook NN cord-015369-72cjogxz 5611 24 - - HYPH cord-015369-72cjogxz 5611 25 wire wire NN cord-015369-72cjogxz 5611 26 was be VBD cord-015369-72cjogxz 5611 27 placed place VBN cord-015369-72cjogxz 5611 28 at at IN cord-015369-72cjogxz 5611 29 the the DT cord-015369-72cjogxz 5611 30 position position NN cord-015369-72cjogxz 5611 31 of of IN cord-015369-72cjogxz 5611 32 the the DT cord-015369-72cjogxz 5611 33 presumptive presumptive JJ cord-015369-72cjogxz 5611 34 lesion lesion NN cord-015369-72cjogxz 5611 35 . . . cord-015369-72cjogxz 5612 1 Afterwards afterwards RB cord-015369-72cjogxz 5612 2 the the DT cord-015369-72cjogxz 5612 3 patient patient NN cord-015369-72cjogxz 5612 4 was be VBD cord-015369-72cjogxz 5612 5 brought bring VBN cord-015369-72cjogxz 5612 6 into into IN cord-015369-72cjogxz 5612 7 the the DT cord-015369-72cjogxz 5612 8 operating operating NN cord-015369-72cjogxz 5612 9 room room NN cord-015369-72cjogxz 5612 10 and and CC cord-015369-72cjogxz 5612 11 an an DT cord-015369-72cjogxz 5612 12 atypical atypical JJ cord-015369-72cjogxz 5612 13 liver liver NN cord-015369-72cjogxz 5612 14 segment segment NN cord-015369-72cjogxz 5612 15 resection resection NN cord-015369-72cjogxz 5612 16 around around IN cord-015369-72cjogxz 5612 17 the the DT cord-015369-72cjogxz 5612 18 pike pike NN cord-015369-72cjogxz 5612 19 of of IN cord-015369-72cjogxz 5612 20 the the DT cord-015369-72cjogxz 5612 21 wire wire NN cord-015369-72cjogxz 5612 22 was be VBD cord-015369-72cjogxz 5612 23 performed perform VBN cord-015369-72cjogxz 5612 24 . . . cord-015369-72cjogxz 5613 1 The the DT cord-015369-72cjogxz 5613 2 operative operative JJ cord-015369-72cjogxz 5613 3 and and CC cord-015369-72cjogxz 5613 4 postoperative postoperative JJ cord-015369-72cjogxz 5613 5 course course NN cord-015369-72cjogxz 5613 6 was be VBD cord-015369-72cjogxz 5613 7 uneventful uneventful JJ cord-015369-72cjogxz 5613 8 . . . cord-015369-72cjogxz 5614 1 The the DT cord-015369-72cjogxz 5614 2 histologic histologic JJ cord-015369-72cjogxz 5614 3 specimen specimen NN cord-015369-72cjogxz 5614 4 was be VBD cord-015369-72cjogxz 5614 5 tumor tumor NN cord-015369-72cjogxz 5614 6 - - HYPH cord-015369-72cjogxz 5614 7 free free JJ cord-015369-72cjogxz 5614 8 also also RB cord-015369-72cjogxz 5614 9 presenting present VBG cord-015369-72cjogxz 5614 10 complete complete JJ cord-015369-72cjogxz 5614 11 pathologic pathologic JJ cord-015369-72cjogxz 5614 12 response response NN cord-015369-72cjogxz 5614 13 . . . cord-015369-72cjogxz 5615 1 After after IN cord-015369-72cjogxz 5615 2 close close JJ cord-015369-72cjogxz 5615 3 follow follow NN cord-015369-72cjogxz 5615 4 - - HYPH cord-015369-72cjogxz 5615 5 up up NN cord-015369-72cjogxz 5615 6 of of IN cord-015369-72cjogxz 5615 7 9 9 CD cord-015369-72cjogxz 5615 8 months month NNS cord-015369-72cjogxz 5615 9 the the DT cord-015369-72cjogxz 5615 10 patient patient NN cord-015369-72cjogxz 5615 11 is be VBZ cord-015369-72cjogxz 5615 12 free free JJ cord-015369-72cjogxz 5615 13 of of IN cord-015369-72cjogxz 5615 14 tumor tumor NN cord-015369-72cjogxz 5615 15 . . . cord-015369-72cjogxz 5616 1 Conclusions conclusion NNS cord-015369-72cjogxz 5616 2 . . . cord-015369-72cjogxz 5617 1 Our -PRON- PRP$ cord-015369-72cjogxz 5617 2 approach approach NN cord-015369-72cjogxz 5617 3 with with IN cord-015369-72cjogxz 5617 4 the the DT cord-015369-72cjogxz 5617 5 CT CT NNP cord-015369-72cjogxz 5617 6 - - HYPH cord-015369-72cjogxz 5617 7 guided guide VBN cord-015369-72cjogxz 5617 8 wire wire NN cord-015369-72cjogxz 5617 9 marking marking NN cord-015369-72cjogxz 5617 10 could could MD cord-015369-72cjogxz 5617 11 potentially potentially RB cord-015369-72cjogxz 5617 12 be be VB cord-015369-72cjogxz 5617 13 a a DT cord-015369-72cjogxz 5617 14 way way NN cord-015369-72cjogxz 5617 15 to to TO cord-015369-72cjogxz 5617 16 remove remove VB cord-015369-72cjogxz 5617 17 colorectal colorectal JJ cord-015369-72cjogxz 5617 18 liver liver NN cord-015369-72cjogxz 5617 19 metastases metastasis NNS cord-015369-72cjogxz 5617 20 with with IN cord-015369-72cjogxz 5617 21 complete complete JJ cord-015369-72cjogxz 5617 22 response response NN cord-015369-72cjogxz 5617 23 to to IN cord-015369-72cjogxz 5617 24 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 5617 25 chemotherapy chemotherapy NN cord-015369-72cjogxz 5617 26 . . . cord-015369-72cjogxz 5618 1 To to TO cord-015369-72cjogxz 5618 2 leave leave VB cord-015369-72cjogxz 5618 3 lesions lesion NNS cord-015369-72cjogxz 5618 4 in in IN cord-015369-72cjogxz 5618 5 place place NN cord-015369-72cjogxz 5618 6 which which WDT cord-015369-72cjogxz 5618 7 are be VBP cord-015369-72cjogxz 5618 8 not not RB cord-015369-72cjogxz 5618 9 visible visible JJ cord-015369-72cjogxz 5618 10 could could MD cord-015369-72cjogxz 5618 11 not not RB cord-015369-72cjogxz 5618 12 be be VB cord-015369-72cjogxz 5618 13 the the DT cord-015369-72cjogxz 5618 14 goal goal NN cord-015369-72cjogxz 5618 15 , , , cord-015369-72cjogxz 5618 16 only only RB cord-015369-72cjogxz 5618 17 a a DT cord-015369-72cjogxz 5618 18 curative curative JJ cord-015369-72cjogxz 5618 19 resection resection NN cord-015369-72cjogxz 5618 20 which which WDT cord-015369-72cjogxz 5618 21 removes remove VBZ cord-015369-72cjogxz 5618 22 all all DT cord-015369-72cjogxz 5618 23 metastases metastasis NNS cord-015369-72cjogxz 5618 24 should should MD cord-015369-72cjogxz 5618 25 be be VB cord-015369-72cjogxz 5618 26 the the DT cord-015369-72cjogxz 5618 27 aim aim NN cord-015369-72cjogxz 5618 28 . . . cord-015369-72cjogxz 5619 1 Rechtsseitiger Rechtsseitiger NNP cord-015369-72cjogxz 5619 2 Oberbauchschmerz Oberbauchschmerz NNP cord-015369-72cjogxz 5619 3 -Ein -ein NN cord-015369-72cjogxz 5619 4 klarer klarer NNP cord-015369-72cjogxz 5619 5 Fall fall VB cord-015369-72cjogxz 5619 6 ? ? . cord-015369-72cjogxz 5620 1 Background background NN cord-015369-72cjogxz 5620 2 . . . cord-015369-72cjogxz 5621 1 Breast breast NN cord-015369-72cjogxz 5621 2 cancer cancer NN cord-015369-72cjogxz 5621 3 metastases metastasis NNS cord-015369-72cjogxz 5621 4 to to IN cord-015369-72cjogxz 5621 5 the the DT cord-015369-72cjogxz 5621 6 liver liver NN cord-015369-72cjogxz 5621 7 are be VBP cord-015369-72cjogxz 5621 8 associated associate VBN cord-015369-72cjogxz 5621 9 with with IN cord-015369-72cjogxz 5621 10 a a DT cord-015369-72cjogxz 5621 11 poor poor JJ cord-015369-72cjogxz 5621 12 prognosis prognosis NN cord-015369-72cjogxz 5621 13 . . . cord-015369-72cjogxz 5622 1 In in IN cord-015369-72cjogxz 5622 2 contrast contrast NN cord-015369-72cjogxz 5622 3 to to IN cord-015369-72cjogxz 5622 4 colorectal colorectal JJ cord-015369-72cjogxz 5622 5 metastases metastasis NNS cord-015369-72cjogxz 5622 6 , , , cord-015369-72cjogxz 5622 7 there there EX cord-015369-72cjogxz 5622 8 are be VBP cord-015369-72cjogxz 5622 9 as as RB cord-015369-72cjogxz 5622 10 yet yet RB cord-015369-72cjogxz 5622 11 no no DT cord-015369-72cjogxz 5622 12 established establish VBN cord-015369-72cjogxz 5622 13 guidelines guideline NNS cord-015369-72cjogxz 5622 14 for for IN cord-015369-72cjogxz 5622 15 liver liver NN cord-015369-72cjogxz 5622 16 surgery surgery NN cord-015369-72cjogxz 5622 17 for for IN cord-015369-72cjogxz 5622 18 breast breast NN cord-015369-72cjogxz 5622 19 cancer cancer NN cord-015369-72cjogxz 5622 20 secondaries secondary NNS cord-015369-72cjogxz 5622 21 . . . cord-015369-72cjogxz 5623 1 Methods method NNS cord-015369-72cjogxz 5623 2 . . . cord-015369-72cjogxz 5624 1 Our -PRON- PRP$ cord-015369-72cjogxz 5624 2 retrospective retrospective JJ cord-015369-72cjogxz 5624 3 study study NN cord-015369-72cjogxz 5624 4 compared compare VBD cord-015369-72cjogxz 5624 5 14 14 CD cord-015369-72cjogxz 5624 6 patients patient NNS cord-015369-72cjogxz 5624 7 with with IN cord-015369-72cjogxz 5624 8 an an DT cord-015369-72cjogxz 5624 9 average average JJ cord-015369-72cjogxz 5624 10 age age NN cord-015369-72cjogxz 5624 11 of of IN cord-015369-72cjogxz 5624 12 55.4 55.4 CD cord-015369-72cjogxz 5624 13 years year NNS cord-015369-72cjogxz 5625 1 ( ( -LRB- cord-015369-72cjogxz 5625 2 range range NN cord-015369-72cjogxz 5625 3 35 35 CD cord-015369-72cjogxz 5625 4 - - SYM cord-015369-72cjogxz 5625 5 81 81 CD cord-015369-72cjogxz 5625 6 years year NNS cord-015369-72cjogxz 5625 7 ) ) -RRB- cord-015369-72cjogxz 5625 8 who who WP cord-015369-72cjogxz 5625 9 underwent undergo VBD cord-015369-72cjogxz 5625 10 hepatic hepatic JJ cord-015369-72cjogxz 5625 11 resection resection NN cord-015369-72cjogxz 5625 12 . . . cord-015369-72cjogxz 5626 1 Both both DT cord-015369-72cjogxz 5626 2 solitary solitary JJ cord-015369-72cjogxz 5626 3 and and CC cord-015369-72cjogxz 5626 4 multiple multiple JJ cord-015369-72cjogxz 5626 5 liver liver NN cord-015369-72cjogxz 5626 6 metastases metastasis NNS cord-015369-72cjogxz 5626 7 that that WDT cord-015369-72cjogxz 5626 8 seemed seem VBD cord-015369-72cjogxz 5626 9 to to TO cord-015369-72cjogxz 5626 10 be be VB cord-015369-72cjogxz 5626 11 resectable resectable JJ cord-015369-72cjogxz 5626 12 by by IN cord-015369-72cjogxz 5626 13 R0 R0 NNP cord-015369-72cjogxz 5626 14 were be VBD cord-015369-72cjogxz 5626 15 treated treat VBN cord-015369-72cjogxz 5626 16 . . . cord-015369-72cjogxz 5627 1 Six six CD cord-015369-72cjogxz 5627 2 patients patient NNS cord-015369-72cjogxz 5627 3 underwent undergo VBD cord-015369-72cjogxz 5627 4 chemotherapy chemotherapy NN cord-015369-72cjogxz 5627 5 before before IN cord-015369-72cjogxz 5627 6 and and CC cord-015369-72cjogxz 5627 7 8 8 CD cord-015369-72cjogxz 5627 8 patients patient NNS cord-015369-72cjogxz 5627 9 after after IN cord-015369-72cjogxz 5627 10 the the DT cord-015369-72cjogxz 5627 11 liver liver NN cord-015369-72cjogxz 5627 12 resection resection NN cord-015369-72cjogxz 5627 13 . . . cord-015369-72cjogxz 5628 1 Nine nine CD cord-015369-72cjogxz 5628 2 women woman NNS cord-015369-72cjogxz 5628 3 received receive VBD cord-015369-72cjogxz 5628 4 hormone hormone NN cord-015369-72cjogxz 5628 5 treatment treatment NN cord-015369-72cjogxz 5628 6 , , , cord-015369-72cjogxz 5628 7 3 3 CD cord-015369-72cjogxz 5628 8 before before RB cord-015369-72cjogxz 5628 9 and and CC cord-015369-72cjogxz 5628 10 6 6 CD cord-015369-72cjogxz 5628 11 after after IN cord-015369-72cjogxz 5628 12 liver liver NN cord-015369-72cjogxz 5628 13 surgery surgery NN cord-015369-72cjogxz 5628 14 . . . cord-015369-72cjogxz 5629 1 Results result NNS cord-015369-72cjogxz 5629 2 . . . cord-015369-72cjogxz 5630 1 We -PRON- PRP cord-015369-72cjogxz 5630 2 performed perform VBD cord-015369-72cjogxz 5630 3 6 6 CD cord-015369-72cjogxz 5630 4 major major JJ cord-015369-72cjogxz 5630 5 ( ( -LRB- cord-015369-72cjogxz 5630 6 hemihepatectomy hemihepatectomy NN cord-015369-72cjogxz 5630 7 or or CC cord-015369-72cjogxz 5630 8 more more JJR cord-015369-72cjogxz 5630 9 than than IN cord-015369-72cjogxz 5630 10 3 3 CD cord-015369-72cjogxz 5630 11 segments segment NNS cord-015369-72cjogxz 5630 12 of of IN cord-015369-72cjogxz 5630 13 the the DT cord-015369-72cjogxz 5630 14 liver liver NN cord-015369-72cjogxz 5630 15 ) ) -RRB- cord-015369-72cjogxz 5630 16 and and CC cord-015369-72cjogxz 5630 17 8 8 CD cord-015369-72cjogxz 5630 18 Minor minor JJ cord-015369-72cjogxz 5630 19 ( ( -LRB- cord-015369-72cjogxz 5630 20 less less JJR cord-015369-72cjogxz 5630 21 than than IN cord-015369-72cjogxz 5630 22 3 3 CD cord-015369-72cjogxz 5630 23 segments segment NNS cord-015369-72cjogxz 5630 24 ) ) -RRB- cord-015369-72cjogxz 5630 25 resections resection NNS cord-015369-72cjogxz 5630 26 . . . cord-015369-72cjogxz 5631 1 The the DT cord-015369-72cjogxz 5631 2 median median JJ cord-015369-72cjogxz 5631 3 interval interval NN cord-015369-72cjogxz 5631 4 between between IN cord-015369-72cjogxz 5631 5 primary primary JJ cord-015369-72cjogxz 5631 6 operation operation NN cord-015369-72cjogxz 5631 7 and and CC cord-015369-72cjogxz 5631 8 liver liver NN cord-015369-72cjogxz 5631 9 resection resection NN cord-015369-72cjogxz 5631 10 was be VBD cord-015369-72cjogxz 5631 11 1.8 1.8 CD cord-015369-72cjogxz 5631 12 years year NNS cord-015369-72cjogxz 5632 1 ( ( -LRB- cord-015369-72cjogxz 5632 2 range range NN cord-015369-72cjogxz 5632 3 4 4 CD cord-015369-72cjogxz 5632 4 months month NNS cord-015369-72cjogxz 5632 5 to to IN cord-015369-72cjogxz 5632 6 9 9 CD cord-015369-72cjogxz 5632 7 years year NNS cord-015369-72cjogxz 5632 8 ) ) -RRB- cord-015369-72cjogxz 5632 9 . . . cord-015369-72cjogxz 5633 1 Fifty fifty CD cord-015369-72cjogxz 5633 2 percent percent NN cord-015369-72cjogxz 5633 3 of of IN cord-015369-72cjogxz 5633 4 the the DT cord-015369-72cjogxz 5633 5 women woman NNS cord-015369-72cjogxz 5633 6 had have VBD cord-015369-72cjogxz 5633 7 a a DT cord-015369-72cjogxz 5633 8 solitary solitary JJ cord-015369-72cjogxz 5633 9 metastasis metastasis NN cord-015369-72cjogxz 5633 10 with with IN cord-015369-72cjogxz 5633 11 a a DT cord-015369-72cjogxz 5633 12 median median JJ cord-015369-72cjogxz 5633 13 size size NN cord-015369-72cjogxz 5633 14 of of IN cord-015369-72cjogxz 5633 15 3 3 CD cord-015369-72cjogxz 5633 16 cm cm NNS cord-015369-72cjogxz 5633 17 . . . cord-015369-72cjogxz 5634 1 There there EX cord-015369-72cjogxz 5634 2 were be VBD cord-015369-72cjogxz 5634 3 liver liver NN cord-015369-72cjogxz 5634 4 secondaries secondary NNS cord-015369-72cjogxz 5634 5 in in IN cord-015369-72cjogxz 5634 6 both both DT cord-015369-72cjogxz 5634 7 lobes lobe NNS cord-015369-72cjogxz 5634 8 in in IN cord-015369-72cjogxz 5634 9 6 6 CD cord-015369-72cjogxz 5634 10 patients patient NNS cord-015369-72cjogxz 5634 11 and and CC cord-015369-72cjogxz 5634 12 in in IN cord-015369-72cjogxz 5634 13 one one CD cord-015369-72cjogxz 5634 14 lobe lobe NN cord-015369-72cjogxz 5634 15 in in IN cord-015369-72cjogxz 5634 16 8 8 CD cord-015369-72cjogxz 5634 17 . . . cord-015369-72cjogxz 5635 1 No no DT cord-015369-72cjogxz 5635 2 patient patient NN cord-015369-72cjogxz 5635 3 died die VBD cord-015369-72cjogxz 5635 4 after after IN cord-015369-72cjogxz 5635 5 liver liver NN cord-015369-72cjogxz 5635 6 resection resection NN cord-015369-72cjogxz 5635 7 . . . cord-015369-72cjogxz 5636 1 Five five CD cord-015369-72cjogxz 5636 2 of of IN cord-015369-72cjogxz 5636 3 the the DT cord-015369-72cjogxz 5636 4 women woman NNS cord-015369-72cjogxz 5636 5 had have VBD cord-015369-72cjogxz 5636 6 a a DT cord-015369-72cjogxz 5636 7 liver liver NN cord-015369-72cjogxz 5636 8 recurrence recurrence NN cord-015369-72cjogxz 5636 9 . . . cord-015369-72cjogxz 5637 1 The the DT cord-015369-72cjogxz 5637 2 3-and 3-and CD cord-015369-72cjogxz 5637 3 5-year 5-year CD cord-015369-72cjogxz 5637 4 survival survival NN cord-015369-72cjogxz 5637 5 rates rate NNS cord-015369-72cjogxz 5637 6 were be VBD cord-015369-72cjogxz 5637 7 calculated calculate VBN cord-015369-72cjogxz 5637 8 as as IN cord-015369-72cjogxz 5637 9 50 50 CD cord-015369-72cjogxz 5637 10 % % NN cord-015369-72cjogxz 5637 11 and and CC cord-015369-72cjogxz 5637 12 20 20 CD cord-015369-72cjogxz 5637 13 % % NN cord-015369-72cjogxz 5637 14 , , , cord-015369-72cjogxz 5637 15 respectively respectively RB cord-015369-72cjogxz 5637 16 . . . cord-015369-72cjogxz 5638 1 Conclusions conclusion NNS cord-015369-72cjogxz 5638 2 . . . cord-015369-72cjogxz 5639 1 For for IN cord-015369-72cjogxz 5639 2 selected select VBN cord-015369-72cjogxz 5639 3 patients patient NNS cord-015369-72cjogxz 5639 4 with with IN cord-015369-72cjogxz 5639 5 liver liver NN cord-015369-72cjogxz 5639 6 secondaries secondary NNS cord-015369-72cjogxz 5639 7 from from IN cord-015369-72cjogxz 5639 8 breast breast NN cord-015369-72cjogxz 5639 9 cancer cancer NN cord-015369-72cjogxz 5639 10 , , , cord-015369-72cjogxz 5639 11 surgical surgical JJ cord-015369-72cjogxz 5639 12 resection resection NN cord-015369-72cjogxz 5639 13 in in IN cord-015369-72cjogxz 5639 14 combination combination NN cord-015369-72cjogxz 5639 15 with with IN cord-015369-72cjogxz 5639 16 chemotherapy chemotherapy NN cord-015369-72cjogxz 5639 17 can can MD cord-015369-72cjogxz 5639 18 be be VB cord-015369-72cjogxz 5639 19 a a DT cord-015369-72cjogxz 5639 20 safe safe JJ cord-015369-72cjogxz 5639 21 option option NN cord-015369-72cjogxz 5639 22 with with IN cord-015369-72cjogxz 5639 23 low low JJ cord-015369-72cjogxz 5639 24 morbidity morbidity NN cord-015369-72cjogxz 5639 25 and and CC cord-015369-72cjogxz 5639 26 mortality mortality NN cord-015369-72cjogxz 5639 27 . . . cord-015369-72cjogxz 5640 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 5640 2 . . . cord-015369-72cjogxz 5641 1 Innerhalb Innerhalb NNP cord-015369-72cjogxz 5641 2 der der NN cord-015369-72cjogxz 5641 3 neoadjuvanten neoadjuvanten NNP cord-015369-72cjogxz 5641 4 Avastin Avastin NNP cord-015369-72cjogxz 5641 5 Therapie Therapie NNP cord-015369-72cjogxz 5641 6 stiegen stiegen NNP cord-015369-72cjogxz 5641 7 TEMs TEMs NNPS cord-015369-72cjogxz 5641 8 und und IN cord-015369-72cjogxz 5641 9 CECs CECs NNP cord-015369-72cjogxz 5641 10 signifikant signifikant VBP cord-015369-72cjogxz 5641 11 an an DT cord-015369-72cjogxz 5641 12 ( ( -LRB- cord-015369-72cjogxz 5641 13 p p NN cord-015369-72cjogxz 5641 14 ¼ ¼ NNP cord-015369-72cjogxz 5641 15 0,036 0,036 CD cord-015369-72cjogxz 5641 16 bzw bzw NNP cord-015369-72cjogxz 5641 17 . . . cord-015369-72cjogxz 5642 1 p p NN cord-015369-72cjogxz 5642 2 ¼ ¼ NNP cord-015369-72cjogxz 5642 3 0,025 0,025 CD cord-015369-72cjogxz 5642 4 ) ) -RRB- cord-015369-72cjogxz 5642 5 . . . cord-015369-72cjogxz 5643 1 Ebenso Ebenso NNP cord-015369-72cjogxz 5644 1 beobachteten beobachteten NNP cord-015369-72cjogxz 5645 1 wir wir NNP cord-015369-72cjogxz 5646 1 i i PRP cord-015369-72cjogxz 5647 1 m m LS cord-015369-72cjogxz 5647 2 VEGF VEGF NNP cord-015369-72cjogxz 5647 3 Verlauf Verlauf NNP cord-015369-72cjogxz 5648 1 einen einen NNP cord-015369-72cjogxz 5648 2 rapiden rapiden JJ cord-015369-72cjogxz 5648 3 Anstieg Anstieg NNP cord-015369-72cjogxz 5648 4 ( ( -LRB- cord-015369-72cjogxz 5649 1 p p NNP cord-015369-72cjogxz 5649 2 ¼ ¼ NNP cord-015369-72cjogxz 5649 3 0,012 0,012 CD cord-015369-72cjogxz 5649 4 ) ) -RRB- cord-015369-72cjogxz 5650 1 , , , cord-015369-72cjogxz 5650 2 der der NNP cord-015369-72cjogxz 5650 3 einem einem NNP cord-015369-72cjogxz 5650 4 deutlichen deutlichen NNP cord-015369-72cjogxz 5650 5 CEA CEA NNP cord-015369-72cjogxz 5650 6 Abfall Abfall NNP cord-015369-72cjogxz 5650 7 gegenüberstand gegenüberstand NNP cord-015369-72cjogxz 5650 8 . . . cord-015369-72cjogxz 5651 1 In in IN cord-015369-72cjogxz 5651 2 der der NNP cord-015369-72cjogxz 5651 3 adjuvanten adjuvanten NNP cord-015369-72cjogxz 5651 4 Therapie Therapie NNP cord-015369-72cjogxz 5651 5 war war NN cord-015369-72cjogxz 5651 6 wiederum wiederum NNP cord-015369-72cjogxz 5651 7 ein ein NNP cord-015369-72cjogxz 5651 8 vergleichbarer vergleichbarer NN cord-015369-72cjogxz 5651 9 VEGF VEGF NNP cord-015369-72cjogxz 5651 10 Anstieg Anstieg NNP cord-015369-72cjogxz 5651 11 ( ( -LRB- cord-015369-72cjogxz 5651 12 p p NN cord-015369-72cjogxz 5651 13 ¼ ¼ NNP cord-015369-72cjogxz 5651 14 0,043 0,043 CD cord-015369-72cjogxz 5651 15 ) ) -RRB- cord-015369-72cjogxz 5652 1 zu zu NNP cord-015369-72cjogxz 5652 2 beobachten beobachten NNP cord-015369-72cjogxz 5652 3 , , , cord-015369-72cjogxz 5652 4 wohingegen wohingegen NNP cord-015369-72cjogxz 5652 5 sich sich NNP cord-015369-72cjogxz 5652 6 sowohl sowohl NNP cord-015369-72cjogxz 5652 7 CECs CECs NNP cord-015369-72cjogxz 5652 8 und und IN cord-015369-72cjogxz 5652 9 TEMs TEMs NNPS cord-015369-72cjogxz 5652 10 als als NNP cord-015369-72cjogxz 5652 11 auch auch NNP cord-015369-72cjogxz 5652 12 CEA CEA NNP cord-015369-72cjogxz 5652 13 kaum kaum NNP cord-015369-72cjogxz 5652 14 veränderten veränderten NNP cord-015369-72cjogxz 5652 15 . . . cord-015369-72cjogxz 5653 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 5653 2 . . . cord-015369-72cjogxz 5654 1 Der Der NNP cord-015369-72cjogxz 5654 2 VEGF VEGF NNP cord-015369-72cjogxz 5654 3 Anstieg Anstieg NNP cord-015369-72cjogxz 5654 4 unter unter JJ cord-015369-72cjogxz 5654 5 neoadjuvanter neoadjuvanter NN cord-015369-72cjogxz 5654 6 und und RB cord-015369-72cjogxz 5654 7 adjuvanter adjuvanter NNP cord-015369-72cjogxz 5654 8 Therapie Therapie NNP cord-015369-72cjogxz 5654 9 scheint scheint NNP cord-015369-72cjogxz 5654 10 den den NNP cord-015369-72cjogxz 5655 1 Einfluss Einfluss NNP cord-015369-72cjogxz 5655 2 von von NNP cord-015369-72cjogxz 5655 3 Avastin Avastin NNP cord-015369-72cjogxz 5655 4 auf auf NNP cord-015369-72cjogxz 5655 5 die die VBP cord-015369-72cjogxz 5655 6 systemische systemische JJ cord-015369-72cjogxz 5655 7 Angiogenesebalance Angiogenesebalance NNP cord-015369-72cjogxz 5655 8 widerzuspiegeln widerzuspiegeln NN cord-015369-72cjogxz 5655 9 . . . cord-015369-72cjogxz 5656 1 Dies die VBZ cord-015369-72cjogxz 5656 2 steht steht NNP cord-015369-72cjogxz 5656 3 dem dem NNP cord-015369-72cjogxz 5656 4 ausschließlich ausschließlich NNP cord-015369-72cjogxz 5656 5 in in IN cord-015369-72cjogxz 5656 6 der der NNP cord-015369-72cjogxz 5656 7 neoadjuvanten neoadjuvanten NNP cord-015369-72cjogxz 5656 8 Therapie Therapie NNP cord-015369-72cjogxz 5656 9 auftretenden auftretenden VBD cord-015369-72cjogxz 5656 10 Anstieg Anstieg NNP cord-015369-72cjogxz 5656 11 der der NNP cord-015369-72cjogxz 5656 12 CECs CECs NNP cord-015369-72cjogxz 5657 1 und und IN cord-015369-72cjogxz 5657 2 TEMs TEMs NNPS cord-015369-72cjogxz 5657 3 gegenüber gegenüber NNP cord-015369-72cjogxz 5657 4 , , , cord-015369-72cjogxz 5657 5 welcher welcher NNP cord-015369-72cjogxz 5657 6 nach nach NNP cord-015369-72cjogxz 5657 7 Tumorresektion Tumorresektion NNP cord-015369-72cjogxz 5657 8 nicht nicht NNP cord-015369-72cjogxz 5657 9 mehr mehr NNP cord-015369-72cjogxz 5657 10 zu zu NNP cord-015369-72cjogxz 5657 11 beobachten beobachten NNP cord-015369-72cjogxz 5657 12 ist ist NNP cord-015369-72cjogxz 5657 13 . . . cord-015369-72cjogxz 5658 1 Die die VB cord-015369-72cjogxz 5658 2 vorliegenden vorliegenden NNP cord-015369-72cjogxz 5658 3 Daten Daten NNP cord-015369-72cjogxz 5658 4 deuten deuten NNP cord-015369-72cjogxz 5658 5 darauf darauf NNP cord-015369-72cjogxz 5658 6 hin hin NNP cord-015369-72cjogxz 5658 7 , , , cord-015369-72cjogxz 5658 8 dass dass NNP cord-015369-72cjogxz 5659 1 die die VB cord-015369-72cjogxz 5660 1 Angiogenese Angiogenese NNP cord-015369-72cjogxz 5660 2 assoziierten assoziierten VBD cord-015369-72cjogxz 5660 3 Zellpopulationen Zellpopulationen NNP cord-015369-72cjogxz 5660 4 mit mit NNP cord-015369-72cjogxz 5660 5 der der NNP cord-015369-72cjogxz 5660 6 Tumormasse Tumormasse NNP cord-015369-72cjogxz 5660 7 in in IN cord-015369-72cjogxz 5660 8 Zusammenhang Zusammenhang NNP cord-015369-72cjogxz 5660 9 stehen stehen NNP cord-015369-72cjogxz 5660 10 , , , cord-015369-72cjogxz 5660 11 sich sich NNP cord-015369-72cjogxz 5660 12 unter unter NNP cord-015369-72cjogxz 5660 13 Therapie Therapie NNP cord-015369-72cjogxz 5660 14 signifikant signifikant NN cord-015369-72cjogxz 5660 15 verändern verändern NNP cord-015369-72cjogxz 5660 16 und und NNP cord-015369-72cjogxz 5660 17 daher daher NNP cord-015369-72cjogxz 5660 18 ein ein NNP cord-015369-72cjogxz 5660 19 Potenzial Potenzial NNP cord-015369-72cjogxz 5661 1 i -PRON- PRP cord-015369-72cjogxz 5661 2 m be VBP cord-015369-72cjogxz 5661 3 Monitoring Monitoring NNP cord-015369-72cjogxz 5661 4 der der NNP cord-015369-72cjogxz 5661 5 kombinierten kombinierten NNP cord-015369-72cjogxz 5661 6 Avastin Avastin NNP cord-015369-72cjogxz 5661 7 - - HYPH cord-015369-72cjogxz 5661 8 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 5661 9 besitzen besitzen NNS cord-015369-72cjogxz 5661 10 . . . cord-015369-72cjogxz 5662 1 Rescue rescue NN cord-015369-72cjogxz 5662 2 approach approach NN cord-015369-72cjogxz 5662 3 for for IN cord-015369-72cjogxz 5662 4 unexpected unexpected JJ cord-015369-72cjogxz 5662 5 portal portal JJ cord-015369-72cjogxz 5662 6 vein vein NN cord-015369-72cjogxz 5662 7 thrombosis thrombosis NN cord-015369-72cjogxz 5662 8 during during IN cord-015369-72cjogxz 5662 9 orthotopic orthotopic JJ cord-015369-72cjogxz 5662 10 liver liver NN cord-015369-72cjogxz 5662 11 transplantation transplantation NN cord-015369-72cjogxz 5662 12 D. D. NNP cord-015369-72cjogxz 5662 13 Kniepeiss Kniepeiss NNP cord-015369-72cjogxz 5662 14 , , , cord-015369-72cjogxz 5662 15 H. H. NNP cord-015369-72cjogxz 5662 16 Müller Müller NNP cord-015369-72cjogxz 5662 17 , , , cord-015369-72cjogxz 5662 18 D. D. NNP cord-015369-72cjogxz 5662 19 Wagner Wagner NNP cord-015369-72cjogxz 5662 20 , , , cord-015369-72cjogxz 5662 21 E. E. NNP cord-015369-72cjogxz 5662 22 Jakoby Jakoby NNP cord-015369-72cjogxz 5662 23 , , , cord-015369-72cjogxz 5662 24 S. S. NNP cord-015369-72cjogxz 5662 25 Schaffellner Schaffellner NNP cord-015369-72cjogxz 5662 26 , , , cord-015369-72cjogxz 5662 27 F. F. NNP cord-015369-72cjogxz 5662 28 Iberer Iberer NNP cord-015369-72cjogxz 5662 29 , , , cord-015369-72cjogxz 5662 30 K. K. NNP cord-015369-72cjogxz 5662 31 Tscheliessnigg Tscheliessnigg NNP cord-015369-72cjogxz 5662 32 Thanks thank NNS cord-015369-72cjogxz 5662 33 to to IN cord-015369-72cjogxz 5662 34 innovative innovative JJ cord-015369-72cjogxz 5662 35 surgical surgical JJ cord-015369-72cjogxz 5662 36 techniques technique NNS cord-015369-72cjogxz 5662 37 , , , cord-015369-72cjogxz 5662 38 portal portal JJ cord-015369-72cjogxz 5662 39 venous venous JJ cord-015369-72cjogxz 5662 40 thrombosis thrombosis NN cord-015369-72cjogxz 5662 41 no no RB cord-015369-72cjogxz 5662 42 longer long RBR cord-015369-72cjogxz 5662 43 is be VBZ cord-015369-72cjogxz 5662 44 a a DT cord-015369-72cjogxz 5662 45 contraindication contraindication NN cord-015369-72cjogxz 5662 46 for for IN cord-015369-72cjogxz 5662 47 liver liver NN cord-015369-72cjogxz 5662 48 transplantation transplantation NN cord-015369-72cjogxz 5662 49 . . . cord-015369-72cjogxz 5663 1 In in IN cord-015369-72cjogxz 5663 2 case case NN cord-015369-72cjogxz 5663 3 of of IN cord-015369-72cjogxz 5663 4 extensive extensive JJ cord-015369-72cjogxz 5663 5 portal portal NN cord-015369-72cjogxz 5663 6 and and CC cord-015369-72cjogxz 5663 7 mesenteric mesenteric JJ cord-015369-72cjogxz 5663 8 venous venous JJ cord-015369-72cjogxz 5663 9 thrombosis thrombosis NN cord-015369-72cjogxz 5663 10 , , , cord-015369-72cjogxz 5663 11 cavoportal cavoportal NNP cord-015369-72cjogxz 5663 12 hemitransposition hemitransposition NNP cord-015369-72cjogxz 5663 13 has have VBZ cord-015369-72cjogxz 5663 14 been be VBN cord-015369-72cjogxz 5663 15 described describe VBN cord-015369-72cjogxz 5663 16 as as IN cord-015369-72cjogxz 5663 17 a a DT cord-015369-72cjogxz 5663 18 salvage salvage NN cord-015369-72cjogxz 5663 19 technique technique NN cord-015369-72cjogxz 5663 20 but but CC cord-015369-72cjogxz 5663 21 experience experience NN cord-015369-72cjogxz 5663 22 is be VBZ cord-015369-72cjogxz 5663 23 still still RB cord-015369-72cjogxz 5663 24 limited limited JJ cord-015369-72cjogxz 5663 25 and and CC cord-015369-72cjogxz 5663 26 there there EX cord-015369-72cjogxz 5663 27 is be VBZ cord-015369-72cjogxz 5663 28 a a DT cord-015369-72cjogxz 5663 29 high high JJ cord-015369-72cjogxz 5663 30 risk risk NN cord-015369-72cjogxz 5663 31 of of IN cord-015369-72cjogxz 5663 32 serious serious JJ cord-015369-72cjogxz 5663 33 complications complication NNS cord-015369-72cjogxz 5663 34 . . . cord-015369-72cjogxz 5664 1 We -PRON- PRP cord-015369-72cjogxz 5664 2 present present VBP cord-015369-72cjogxz 5664 3 an an DT cord-015369-72cjogxz 5664 4 alternative alternative JJ cord-015369-72cjogxz 5664 5 management management NN cord-015369-72cjogxz 5664 6 of of IN cord-015369-72cjogxz 5664 7 portal portal JJ cord-015369-72cjogxz 5664 8 vein vein NN cord-015369-72cjogxz 5664 9 thrombosis thrombosis NN cord-015369-72cjogxz 5664 10 during during IN cord-015369-72cjogxz 5664 11 liver liver NN cord-015369-72cjogxz 5664 12 transplantation transplantation NN cord-015369-72cjogxz 5664 13 . . . cord-015369-72cjogxz 5665 1 A a DT cord-015369-72cjogxz 5665 2 61-year 61-year JJ cord-015369-72cjogxz 5665 3 - - HYPH cord-015369-72cjogxz 5665 4 old old JJ cord-015369-72cjogxz 5665 5 man man NN cord-015369-72cjogxz 5665 6 with with IN cord-015369-72cjogxz 5665 7 liver liver NN cord-015369-72cjogxz 5665 8 cirrhosis cirrhosis NN cord-015369-72cjogxz 5665 9 underwent undergo VBD cord-015369-72cjogxz 5665 10 liver liver NN cord-015369-72cjogxz 5665 11 transplantation transplantation NN cord-015369-72cjogxz 5665 12 . . . cord-015369-72cjogxz 5666 1 Although although IN cord-015369-72cjogxz 5666 2 preoperative preoperative JJ cord-015369-72cjogxz 5666 3 Doppler Doppler NNP cord-015369-72cjogxz 5666 4 ultrasound ultrasound NN cord-015369-72cjogxz 5666 5 showed show VBD cord-015369-72cjogxz 5666 6 portal portal JJ cord-015369-72cjogxz 5666 7 perfusion perfusion NN cord-015369-72cjogxz 5666 8 , , , cord-015369-72cjogxz 5666 9 severe severe JJ cord-015369-72cjogxz 5666 10 portal portal JJ cord-015369-72cjogxz 5666 11 vein vein NN cord-015369-72cjogxz 5666 12 thrombosis thrombosis NN cord-015369-72cjogxz 5666 13 was be VBD cord-015369-72cjogxz 5666 14 found find VBN cord-015369-72cjogxz 5666 15 during during IN cord-015369-72cjogxz 5666 16 transplantation transplantation NN cord-015369-72cjogxz 5666 17 . . . cord-015369-72cjogxz 5667 1 Obviously obviously RB cord-015369-72cjogxz 5667 2 , , , cord-015369-72cjogxz 5667 3 the the DT cord-015369-72cjogxz 5667 4 flow flow NN cord-015369-72cjogxz 5667 5 of of IN cord-015369-72cjogxz 5667 6 one one CD cord-015369-72cjogxz 5667 7 variceal variceal JJ cord-015369-72cjogxz 5667 8 vein vein NN cord-015369-72cjogxz 5667 9 located locate VBN cord-015369-72cjogxz 5667 10 cranial cranial NN cord-015369-72cjogxz 5667 11 to to IN cord-015369-72cjogxz 5667 12 the the DT cord-015369-72cjogxz 5667 13 hepatic hepatic JJ cord-015369-72cjogxz 5667 14 artery artery NN cord-015369-72cjogxz 5667 15 was be VBD cord-015369-72cjogxz 5667 16 interpreted interpret VBN cord-015369-72cjogxz 5667 17 as as IN cord-015369-72cjogxz 5667 18 portal portal JJ cord-015369-72cjogxz 5667 19 vein vein NN cord-015369-72cjogxz 5667 20 flow flow NN cord-015369-72cjogxz 5667 21 in in IN cord-015369-72cjogxz 5667 22 the the DT cord-015369-72cjogxz 5667 23 pretransplant pretransplant JJ cord-015369-72cjogxz 5667 24 ultrasound ultrasound NN cord-015369-72cjogxz 5667 25 examination examination NN cord-015369-72cjogxz 5667 26 . . . cord-015369-72cjogxz 5668 1 As as IN cord-015369-72cjogxz 5668 2 a a DT cord-015369-72cjogxz 5668 3 salvage salvage NN cord-015369-72cjogxz 5668 4 measure measure NN cord-015369-72cjogxz 5668 5 , , , cord-015369-72cjogxz 5668 6 the the DT cord-015369-72cjogxz 5668 7 variceal variceal JJ cord-015369-72cjogxz 5668 8 collateral collateral NN cord-015369-72cjogxz 5668 9 vein vein NN cord-015369-72cjogxz 5668 10 was be VBD cord-015369-72cjogxz 5668 11 used use VBN cord-015369-72cjogxz 5668 12 for for IN cord-015369-72cjogxz 5668 13 portal portal JJ cord-015369-72cjogxz 5668 14 end end NN cord-015369-72cjogxz 5668 15 - - HYPH cord-015369-72cjogxz 5668 16 to to IN cord-015369-72cjogxz 5668 17 - - HYPH cord-015369-72cjogxz 5668 18 end end NN cord-015369-72cjogxz 5668 19 anastomosis anastomosis NN cord-015369-72cjogxz 5668 20 . . . cord-015369-72cjogxz 5669 1 Postoperatively postoperatively RB cord-015369-72cjogxz 5669 2 , , , cord-015369-72cjogxz 5669 3 primary primary JJ cord-015369-72cjogxz 5669 4 graft graft NN cord-015369-72cjogxz 5669 5 function function NN cord-015369-72cjogxz 5669 6 was be VBD cord-015369-72cjogxz 5669 7 acceptable acceptable JJ cord-015369-72cjogxz 5669 8 and and CC cord-015369-72cjogxz 5669 9 improved improved JJ cord-015369-72cjogxz 5669 10 day day NN cord-015369-72cjogxz 5669 11 by by IN cord-015369-72cjogxz 5669 12 day day NN cord-015369-72cjogxz 5669 13 . . . cord-015369-72cjogxz 5670 1 Moderate moderate JJ cord-015369-72cjogxz 5670 2 renal renal JJ cord-015369-72cjogxz 5670 3 failure failure NN cord-015369-72cjogxz 5670 4 as as IN cord-015369-72cjogxz 5670 5 defined define VBN cord-015369-72cjogxz 5670 6 by by IN cord-015369-72cjogxz 5670 7 the the DT cord-015369-72cjogxz 5670 8 K K NNP cord-015369-72cjogxz 5670 9 / / SYM cord-015369-72cjogxz 5670 10 DOQI DOQI NNP cord-015369-72cjogxz 5670 11 - - HYPH cord-015369-72cjogxz 5670 12 guidelines guideline NNS cord-015369-72cjogxz 5670 13 improved improve VBN cord-015369-72cjogxz 5670 14 gradually gradually RB cord-015369-72cjogxz 5670 15 and and CC cord-015369-72cjogxz 5670 16 dialysis dialysis NN cord-015369-72cjogxz 5670 17 was be VBD cord-015369-72cjogxz 5670 18 never never RB cord-015369-72cjogxz 5670 19 indicated indicate VBN cord-015369-72cjogxz 5670 20 . . . cord-015369-72cjogxz 5671 1 Persistent persistent JJ cord-015369-72cjogxz 5671 2 ascites ascite NNS cord-015369-72cjogxz 5671 3 required require VBD cord-015369-72cjogxz 5671 4 repeated repeat VBD cord-015369-72cjogxz 5671 5 paracentesis paracentesi NNS cord-015369-72cjogxz 5671 6 during during IN cord-015369-72cjogxz 5671 7 the the DT cord-015369-72cjogxz 5671 8 first first JJ cord-015369-72cjogxz 5671 9 month month NN cord-015369-72cjogxz 5671 10 after after IN cord-015369-72cjogxz 5671 11 liver liver NN cord-015369-72cjogxz 5671 12 transplantation transplantation NN cord-015369-72cjogxz 5671 13 but but CC cord-015369-72cjogxz 5671 14 medical medical JJ cord-015369-72cjogxz 5671 15 treatment treatment NN cord-015369-72cjogxz 5671 16 sufficed suffice VBD cord-015369-72cjogxz 5671 17 thereafter thereafter RB cord-015369-72cjogxz 5671 18 . . . cord-015369-72cjogxz 5672 1 Six six CD cord-015369-72cjogxz 5672 2 months month NNS cord-015369-72cjogxz 5672 3 after after IN cord-015369-72cjogxz 5672 4 transplantation transplantation NN cord-015369-72cjogxz 5672 5 the the DT cord-015369-72cjogxz 5672 6 patient patient NN cord-015369-72cjogxz 5672 7 has have VBZ cord-015369-72cjogxz 5672 8 normal normal JJ cord-015369-72cjogxz 5672 9 liver liver NN cord-015369-72cjogxz 5672 10 function function NN cord-015369-72cjogxz 5672 11 and and CC cord-015369-72cjogxz 5672 12 adequate adequate JJ cord-015369-72cjogxz 5672 13 renal renal JJ cord-015369-72cjogxz 5672 14 function function NN cord-015369-72cjogxz 5672 15 . . . cord-015369-72cjogxz 5673 1 Colour Colour NNP cord-015369-72cjogxz 5673 2 Doppler Doppler NNP cord-015369-72cjogxz 5673 3 ultrasound ultrasound NN cord-015369-72cjogxz 5673 4 shows show VBZ cord-015369-72cjogxz 5673 5 normal normal JJ cord-015369-72cjogxz 5673 6 flow flow NN cord-015369-72cjogxz 5673 7 in in IN cord-015369-72cjogxz 5673 8 all all DT cord-015369-72cjogxz 5673 9 vessels vessel NNS cord-015369-72cjogxz 5673 10 . . . cord-015369-72cjogxz 5674 1 There there EX cord-015369-72cjogxz 5674 2 are be VBP cord-015369-72cjogxz 5674 3 no no DT cord-015369-72cjogxz 5674 4 ultrasonographic ultrasonographic JJ cord-015369-72cjogxz 5674 5 signs sign NNS cord-015369-72cjogxz 5674 6 of of IN cord-015369-72cjogxz 5674 7 ascites ascite NNS cord-015369-72cjogxz 5674 8 and and CC cord-015369-72cjogxz 5674 9 diuretics diuretic NNS cord-015369-72cjogxz 5674 10 are be VBP cord-015369-72cjogxz 5674 11 not not RB cord-015369-72cjogxz 5674 12 required require VBN cord-015369-72cjogxz 5674 13 . . . cord-015369-72cjogxz 5675 1 We -PRON- PRP cord-015369-72cjogxz 5675 2 conclude conclude VBP cord-015369-72cjogxz 5675 3 that that IN cord-015369-72cjogxz 5675 4 when when WRB cord-015369-72cjogxz 5675 5 there there EX cord-015369-72cjogxz 5675 6 is be VBZ cord-015369-72cjogxz 5675 7 portal portal JJ cord-015369-72cjogxz 5675 8 vein vein NN cord-015369-72cjogxz 5675 9 thrombosis thrombosis NN cord-015369-72cjogxz 5675 10 , , , cord-015369-72cjogxz 5675 11 a a DT cord-015369-72cjogxz 5675 12 collateral collateral JJ cord-015369-72cjogxz 5675 13 vein vein NN cord-015369-72cjogxz 5675 14 of of IN cord-015369-72cjogxz 5675 15 sufficient sufficient JJ cord-015369-72cjogxz 5675 16 calibre calibre NN cord-015369-72cjogxz 5675 17 in in IN cord-015369-72cjogxz 5675 18 the the DT cord-015369-72cjogxz 5675 19 hilum hilum NN cord-015369-72cjogxz 5675 20 can can MD cord-015369-72cjogxz 5675 21 be be VB cord-015369-72cjogxz 5675 22 used use VBN cord-015369-72cjogxz 5675 23 if if IN cord-015369-72cjogxz 5675 24 present present JJ cord-015369-72cjogxz 5675 25 for for IN cord-015369-72cjogxz 5675 26 portal portal JJ cord-015369-72cjogxz 5675 27 vein vein NN cord-015369-72cjogxz 5675 28 anastomosis anastomosis NN cord-015369-72cjogxz 5675 29 . . . cord-015369-72cjogxz 5676 1 In in IN cord-015369-72cjogxz 5676 2 our -PRON- PRP$ cord-015369-72cjogxz 5676 3 case case NN cord-015369-72cjogxz 5676 4 the the DT cord-015369-72cjogxz 5676 5 surgical surgical JJ cord-015369-72cjogxz 5676 6 procedure procedure NN cord-015369-72cjogxz 5676 7 was be VBD cord-015369-72cjogxz 5676 8 uneventful uneventful JJ cord-015369-72cjogxz 5676 9 ; ; : cord-015369-72cjogxz 5676 10 postoperative postoperative JJ cord-015369-72cjogxz 5676 11 complications complication NNS cord-015369-72cjogxz 5676 12 were be VBD cord-015369-72cjogxz 5676 13 not not RB cord-015369-72cjogxz 5676 14 serious serious JJ cord-015369-72cjogxz 5676 15 and and CC cord-015369-72cjogxz 5676 16 were be VBD cord-015369-72cjogxz 5676 17 controllable controllable JJ cord-015369-72cjogxz 5676 18 with with IN cord-015369-72cjogxz 5676 19 medical medical JJ cord-015369-72cjogxz 5676 20 therapy therapy NN cord-015369-72cjogxz 5676 21 . . . cord-015369-72cjogxz 5677 1 An an DT cord-015369-72cjogxz 5677 2 in in IN cord-015369-72cjogxz 5677 3 - - HYPH cord-015369-72cjogxz 5677 4 vitro vitro FW cord-015369-72cjogxz 5677 5 role role NN cord-015369-72cjogxz 5677 6 of of IN cord-015369-72cjogxz 5677 7 mTOR mTOR NNP cord-015369-72cjogxz 5677 8 proteins protein NNS cord-015369-72cjogxz 5677 9 in in IN cord-015369-72cjogxz 5677 10 the the DT cord-015369-72cjogxz 5677 11 protection protection NN cord-015369-72cjogxz 5677 12 of of IN cord-015369-72cjogxz 5677 13 HCV HCV NNP cord-015369-72cjogxz 5677 14 infected infect VBN cord-015369-72cjogxz 5677 15 cells cell NNS cord-015369-72cjogxz 5677 16 from from IN cord-015369-72cjogxz 5677 17 apoptosis apoptosis NN cord-015369-72cjogxz 5677 18 has have VBZ cord-015369-72cjogxz 5677 19 been be VBN cord-015369-72cjogxz 5677 20 proven prove VBN cord-015369-72cjogxz 5677 21 . . . cord-015369-72cjogxz 5678 1 The the DT cord-015369-72cjogxz 5678 2 aim aim NN cord-015369-72cjogxz 5678 3 of of IN cord-015369-72cjogxz 5678 4 this this DT cord-015369-72cjogxz 5678 5 cohort cohort NN cord-015369-72cjogxz 5678 6 study study NN cord-015369-72cjogxz 5678 7 was be VBD cord-015369-72cjogxz 5678 8 to to TO cord-015369-72cjogxz 5678 9 evaluate evaluate VB cord-015369-72cjogxz 5678 10 the the DT cord-015369-72cjogxz 5678 11 effect effect NN cord-015369-72cjogxz 5678 12 of of IN cord-015369-72cjogxz 5678 13 Sirolimus Sirolimus NNP cord-015369-72cjogxz 5678 14 as as IN cord-015369-72cjogxz 5678 15 mTOR mTOR NNP cord-015369-72cjogxz 5678 16 inhibitor inhibitor NN cord-015369-72cjogxz 5678 17 on on IN cord-015369-72cjogxz 5678 18 Hepatitis Hepatitis NNP cord-015369-72cjogxz 5678 19 C C NNP cord-015369-72cjogxz 5678 20 recurrence recurrence NN cord-015369-72cjogxz 5678 21 in in IN cord-015369-72cjogxz 5678 22 liver liver NN cord-015369-72cjogxz 5678 23 recipients recipient NNS cord-015369-72cjogxz 5678 24 . . . cord-015369-72cjogxz 5679 1 Hepatitis Hepatitis NNP cord-015369-72cjogxz 5679 2 C C NNP cord-015369-72cjogxz 5679 3 virus virus NN cord-015369-72cjogxz 5679 4 positive positive JJ cord-015369-72cjogxz 5679 5 patients patient NNS cord-015369-72cjogxz 5679 6 were be VBD cord-015369-72cjogxz 5679 7 followed follow VBN cord-015369-72cjogxz 5679 8 up up RP cord-015369-72cjogxz 5679 9 prospectively prospectively RB cord-015369-72cjogxz 5679 10 regarding regard VBG cord-015369-72cjogxz 5679 11 transaminases transaminase NNS cord-015369-72cjogxz 5679 12 , , , cord-015369-72cjogxz 5679 13 immunosuppressive immunosuppressive JJ cord-015369-72cjogxz 5679 14 target target NN cord-015369-72cjogxz 5679 15 levels level NNS cord-015369-72cjogxz 5679 16 , , , cord-015369-72cjogxz 5679 17 HCV HCV NNP cord-015369-72cjogxz 5679 18 RNA RNA NNP cord-015369-72cjogxz 5679 19 and and CC cord-015369-72cjogxz 5679 20 influence influence NN cord-015369-72cjogxz 5679 21 of of IN cord-015369-72cjogxz 5679 22 donor donor NN cord-015369-72cjogxz 5679 23 and and CC cord-015369-72cjogxz 5679 24 recipient recipient NN cord-015369-72cjogxz 5679 25 factors factor NNS cord-015369-72cjogxz 5679 26 on on IN cord-015369-72cjogxz 5679 27 viral viral JJ cord-015369-72cjogxz 5679 28 recurrence recurrence NN cord-015369-72cjogxz 5679 29 and and CC cord-015369-72cjogxz 5679 30 survival survival NN cord-015369-72cjogxz 5679 31 . . . cord-015369-72cjogxz 5680 1 Viral viral JJ cord-015369-72cjogxz 5680 2 recurrence recurrence NN cord-015369-72cjogxz 5680 3 was be VBD cord-015369-72cjogxz 5680 4 defined define VBN cord-015369-72cjogxz 5680 5 as as IN cord-015369-72cjogxz 5680 6 elevated elevated JJ cord-015369-72cjogxz 5680 7 liver liver NN cord-015369-72cjogxz 5680 8 enzymes enzyme NNS cord-015369-72cjogxz 5680 9 combined combine VBN cord-015369-72cjogxz 5680 10 with with IN cord-015369-72cjogxz 5680 11 active active JJ cord-015369-72cjogxz 5680 12 hepatitis hepatitis NN cord-015369-72cjogxz 5680 13 defined define VBN cord-015369-72cjogxz 5680 14 as as IN cord-015369-72cjogxz 5680 15 increasing increase VBG cord-015369-72cjogxz 5680 16 viral viral JJ cord-015369-72cjogxz 5680 17 load load NN cord-015369-72cjogxz 5680 18 and/or and/or CC cord-015369-72cjogxz 5680 19 biopsy biopsy NN cord-015369-72cjogxz 5680 20 proven prove VBN cord-015369-72cjogxz 5680 21 HCV HCV NNP cord-015369-72cjogxz 5680 22 relapse relapse NN cord-015369-72cjogxz 5680 23 in in IN cord-015369-72cjogxz 5680 24 the the DT cord-015369-72cjogxz 5680 25 transplanted transplanted JJ cord-015369-72cjogxz 5680 26 organ organ NN cord-015369-72cjogxz 5680 27 . . . cord-015369-72cjogxz 5681 1 67 67 CD cord-015369-72cjogxz 5681 2 HCV HCV NNP cord-015369-72cjogxz 5681 3 - - HYPH cord-015369-72cjogxz 5681 4 positive positive JJ cord-015369-72cjogxz 5681 5 patients patient NNS cord-015369-72cjogxz 5681 6 were be VBD cord-015369-72cjogxz 5681 7 included include VBN cord-015369-72cjogxz 5681 8 39 39 CD cord-015369-72cjogxz 5681 9 received receive VBD cord-015369-72cjogxz 5681 10 a a DT cord-015369-72cjogxz 5681 11 Sirolimus Sirolimus NNP cord-015369-72cjogxz 5681 12 including include VBG cord-015369-72cjogxz 5681 13 regimen regimen NN cord-015369-72cjogxz 5681 14 , , , cord-015369-72cjogxz 5681 15 18 18 CD cord-015369-72cjogxz 5681 16 patients patient NNS cord-015369-72cjogxz 5681 17 stayed stay VBD cord-015369-72cjogxz 5681 18 on on IN cord-015369-72cjogxz 5681 19 calcineurininhibitors calcineurininhibitor NNS cord-015369-72cjogxz 5681 20 . . . cord-015369-72cjogxz 5682 1 Sirolimus Sirolimus NNP cord-015369-72cjogxz 5682 2 patients patient NNS cord-015369-72cjogxz 5682 3 showed show VBD cord-015369-72cjogxz 5682 4 a a DT cord-015369-72cjogxz 5682 5 significant significant JJ cord-015369-72cjogxz 5682 6 decrease decrease NN cord-015369-72cjogxz 5682 7 in in IN cord-015369-72cjogxz 5682 8 the the DT cord-015369-72cjogxz 5682 9 HCV HCV NNP cord-015369-72cjogxz 5682 10 PCR PCR NNP cord-015369-72cjogxz 5682 11 levels level NNS cord-015369-72cjogxz 5682 12 ( ( -LRB- cord-015369-72cjogxz 5682 13 p p NN cord-015369-72cjogxz 5682 14 < < XX cord-015369-72cjogxz 5682 15 0,05 0,05 NNP cord-015369-72cjogxz 5682 16 ) ) -RRB- cord-015369-72cjogxz 5682 17 . . . cord-015369-72cjogxz 5683 1 Survival survival NN cord-015369-72cjogxz 5683 2 of of IN cord-015369-72cjogxz 5683 3 the the DT cord-015369-72cjogxz 5683 4 Sirolimus Sirolimus NNP cord-015369-72cjogxz 5683 5 patients patient NNS cord-015369-72cjogxz 5683 6 was be VBD cord-015369-72cjogxz 5683 7 significantly significantly RB cord-015369-72cjogxz 5683 8 higher high JJR cord-015369-72cjogxz 5683 9 ( ( -LRB- cord-015369-72cjogxz 5683 10 p p NN cord-015369-72cjogxz 5683 11 < < XX cord-015369-72cjogxz 5683 12 0,03 0,03 NFP cord-015369-72cjogxz 5683 13 ) ) -RRB- cord-015369-72cjogxz 5683 14 as as IN cord-015369-72cjogxz 5683 15 compared compare VBN cord-015369-72cjogxz 5683 16 to to IN cord-015369-72cjogxz 5683 17 the the DT cord-015369-72cjogxz 5683 18 other other JJ cord-015369-72cjogxz 5683 19 patient patient JJ cord-015369-72cjogxz 5683 20 cohort cohort NN cord-015369-72cjogxz 5683 21 . . . cord-015369-72cjogxz 5684 1 Sirolimus Sirolimus NNP cord-015369-72cjogxz 5684 2 has have VBZ cord-015369-72cjogxz 5684 3 shown show VBN cord-015369-72cjogxz 5684 4 to to TO cord-015369-72cjogxz 5684 5 be be VB cord-015369-72cjogxz 5684 6 a a DT cord-015369-72cjogxz 5684 7 potent potent JJ cord-015369-72cjogxz 5684 8 immunosuppressive immunosuppressive JJ cord-015369-72cjogxz 5684 9 agent agent NN cord-015369-72cjogxz 5684 10 for for IN cord-015369-72cjogxz 5684 11 patients patient NNS cord-015369-72cjogxz 5684 12 after after IN cord-015369-72cjogxz 5684 13 liver liver NN cord-015369-72cjogxz 5684 14 transplantation transplantation NN cord-015369-72cjogxz 5684 15 . . . cord-015369-72cjogxz 5685 1 Nothing nothing NN cord-015369-72cjogxz 5685 2 is be VBZ cord-015369-72cjogxz 5685 3 known know VBN cord-015369-72cjogxz 5685 4 about about IN cord-015369-72cjogxz 5685 5 its -PRON- PRP$ cord-015369-72cjogxz 5685 6 effect effect NN cord-015369-72cjogxz 5685 7 on on IN cord-015369-72cjogxz 5685 8 HCV HCV NNP cord-015369-72cjogxz 5685 9 . . . cord-015369-72cjogxz 5686 1 This this DT cord-015369-72cjogxz 5686 2 analysis analysis NN cord-015369-72cjogxz 5686 3 suggests suggest VBZ cord-015369-72cjogxz 5686 4 a a DT cord-015369-72cjogxz 5686 5 potential potential NN cord-015369-72cjogxz 5686 6 of of IN cord-015369-72cjogxz 5686 7 Sirolimus Sirolimus NNP cord-015369-72cjogxz 5686 8 to to TO cord-015369-72cjogxz 5686 9 be be VB cord-015369-72cjogxz 5686 10 evaluated evaluate VBN cord-015369-72cjogxz 5686 11 as as RB cord-015369-72cjogxz 5686 12 immunosuppressant immunosuppressant JJ cord-015369-72cjogxz 5686 13 for for IN cord-015369-72cjogxz 5686 14 HCV HCV NNP cord-015369-72cjogxz 5686 15 positive positive JJ cord-015369-72cjogxz 5686 16 liver liver NN cord-015369-72cjogxz 5686 17 transplant transplant NN cord-015369-72cjogxz 5686 18 candidates candidate NNS cord-015369-72cjogxz 5686 19 to to TO cord-015369-72cjogxz 5686 20 suppress suppress VB cord-015369-72cjogxz 5686 21 viral viral JJ cord-015369-72cjogxz 5686 22 recurrence recurrence NN cord-015369-72cjogxz 5686 23 . . . cord-015369-72cjogxz 5687 1 Langerhans Langerhans NNP cord-015369-72cjogxz 5687 2 ' ' POS cord-015369-72cjogxz 5687 3 cell cell NN cord-015369-72cjogxz 5687 4 sarcoma sarcoma NN cord-015369-72cjogxz 5687 5 of of IN cord-015369-72cjogxz 5687 6 the the DT cord-015369-72cjogxz 5687 7 spleensurprising spleensurprising NN cord-015369-72cjogxz 5687 8 diagnosis diagnosis NN cord-015369-72cjogxz 5687 9 of of IN cord-015369-72cjogxz 5687 10 a a DT cord-015369-72cjogxz 5687 11 very very RB cord-015369-72cjogxz 5687 12 rare rare JJ cord-015369-72cjogxz 5687 13 tumor tumor NN cord-015369-72cjogxz 5687 14 entity entity NN cord-015369-72cjogxz 5687 15 during during IN cord-015369-72cjogxz 5687 16 the the DT cord-015369-72cjogxz 5687 17 septic septic JJ cord-015369-72cjogxz 5687 18 course course NN cord-015369-72cjogxz 5687 19 of of IN cord-015369-72cjogxz 5687 20 a a DT cord-015369-72cjogxz 5687 21 patient patient JJ cord-015369-72cjogxz 5687 22 Background background NN cord-015369-72cjogxz 5687 23 . . . cord-015369-72cjogxz 5688 1 CCC CCC NNP cord-015369-72cjogxz 5688 2 is be VBZ cord-015369-72cjogxz 5688 3 a a DT cord-015369-72cjogxz 5688 4 rare rare JJ cord-015369-72cjogxz 5688 5 tumor tumor NN cord-015369-72cjogxz 5688 6 disease disease NN cord-015369-72cjogxz 5688 7 in in IN cord-015369-72cjogxz 5688 8 Western Western NNP cord-015369-72cjogxz 5688 9 Europe Europe NNP cord-015369-72cjogxz 5688 10 with with IN cord-015369-72cjogxz 5688 11 a a DT cord-015369-72cjogxz 5688 12 poor poor JJ cord-015369-72cjogxz 5688 13 prognosis prognosis NN cord-015369-72cjogxz 5688 14 . . . cord-015369-72cjogxz 5689 1 These these DT cord-015369-72cjogxz 5689 2 tumors tumor NNS cord-015369-72cjogxz 5689 3 develop develop VBP cord-015369-72cjogxz 5689 4 from from IN cord-015369-72cjogxz 5689 5 cells cell NNS cord-015369-72cjogxz 5689 6 of of IN cord-015369-72cjogxz 5689 7 the the DT cord-015369-72cjogxz 5689 8 bile bile NN cord-015369-72cjogxz 5689 9 duct duct NN cord-015369-72cjogxz 5689 10 epithelia epithelium NNS cord-015369-72cjogxz 5689 11 and and CC cord-015369-72cjogxz 5689 12 can can MD cord-015369-72cjogxz 5689 13 appear appear VB cord-015369-72cjogxz 5689 14 in in IN cord-015369-72cjogxz 5689 15 several several JJ cord-015369-72cjogxz 5689 16 locations location NNS cord-015369-72cjogxz 5689 17 along along IN cord-015369-72cjogxz 5689 18 the the DT cord-015369-72cjogxz 5689 19 biliary biliary JJ cord-015369-72cjogxz 5689 20 tract tract NN cord-015369-72cjogxz 5689 21 . . . cord-015369-72cjogxz 5690 1 Methods method NNS cord-015369-72cjogxz 5690 2 . . . cord-015369-72cjogxz 5691 1 Between between IN cord-015369-72cjogxz 5691 2 1998 1998 CD cord-015369-72cjogxz 5691 3 and and CC cord-015369-72cjogxz 5691 4 2008 2008 CD cord-015369-72cjogxz 5691 5 a a DT cord-015369-72cjogxz 5691 6 total total NN cord-015369-72cjogxz 5691 7 of of IN cord-015369-72cjogxz 5691 8 215 215 CD cord-015369-72cjogxz 5691 9 Patients patient NNS cord-015369-72cjogxz 5691 10 were be VBD cord-015369-72cjogxz 5691 11 reported report VBN cord-015369-72cjogxz 5691 12 at at IN cord-015369-72cjogxz 5691 13 our -PRON- PRP$ cord-015369-72cjogxz 5691 14 surgical surgical JJ cord-015369-72cjogxz 5691 15 department department NN cord-015369-72cjogxz 5691 16 because because IN cord-015369-72cjogxz 5691 17 of of IN cord-015369-72cjogxz 5691 18 malign malign JJ cord-015369-72cjogxz 5691 19 bile bile NN cord-015369-72cjogxz 5691 20 duct duct NN cord-015369-72cjogxz 5691 21 tumor tumor NN cord-015369-72cjogxz 5691 22 . . . cord-015369-72cjogxz 5692 1 116 116 CD cord-015369-72cjogxz 5692 2 Patients patient NNS cord-015369-72cjogxz 5692 3 with with IN cord-015369-72cjogxz 5692 4 histologically histologically RB cord-015369-72cjogxz 5692 5 confirmed confirm VBN cord-015369-72cjogxz 5692 6 Cholangiocarcinoma Cholangiocarcinoma NNP cord-015369-72cjogxz 5692 7 were be VBD cord-015369-72cjogxz 5692 8 included include VBN cord-015369-72cjogxz 5692 9 in in IN cord-015369-72cjogxz 5692 10 this this DT cord-015369-72cjogxz 5692 11 study study NN cord-015369-72cjogxz 5692 12 . . . cord-015369-72cjogxz 5693 1 Gall gall NN cord-015369-72cjogxz 5693 2 bladder bladder NN cord-015369-72cjogxz 5693 3 and and CC cord-015369-72cjogxz 5693 4 papillary papillary JJ cord-015369-72cjogxz 5693 5 cancer cancer NN cord-015369-72cjogxz 5693 6 were be VBD cord-015369-72cjogxz 5693 7 excluded exclude VBN cord-015369-72cjogxz 5693 8 . . . cord-015369-72cjogxz 5694 1 Patients patient NNS cord-015369-72cjogxz 5694 2 were be VBD cord-015369-72cjogxz 5694 3 classified classify VBN cord-015369-72cjogxz 5694 4 into into IN cord-015369-72cjogxz 5694 5 3 3 CD cord-015369-72cjogxz 5694 6 groupsintrahepatic groupsintrahepatic NN cord-015369-72cjogxz 5694 7 , , , cord-015369-72cjogxz 5694 8 perihilar perihilar JJ cord-015369-72cjogxz 5694 9 and and CC cord-015369-72cjogxz 5694 10 distal distal RB cord-015369-72cjogxz 5694 11 - - HYPH cord-015369-72cjogxz 5694 12 based base VBN cord-015369-72cjogxz 5694 13 on on IN cord-015369-72cjogxz 5694 14 the the DT cord-015369-72cjogxz 5694 15 tumor tumor NN cord-015369-72cjogxz 5694 16 classification classification NN cord-015369-72cjogxz 5694 17 established establish VBN cord-015369-72cjogxz 5694 18 by by IN cord-015369-72cjogxz 5694 19 the the DT cord-015369-72cjogxz 5694 20 John John NNP cord-015369-72cjogxz 5694 21 Hopkins Hopkins NNP cord-015369-72cjogxz 5694 22 Hospital Hospital NNP cord-015369-72cjogxz 5694 23 . . . cord-015369-72cjogxz 5695 1 Data datum NNS cord-015369-72cjogxz 5695 2 was be VBD cord-015369-72cjogxz 5695 3 obtained obtain VBN cord-015369-72cjogxz 5695 4 retrospectively retrospectively RB cord-015369-72cjogxz 5695 5 from from IN cord-015369-72cjogxz 5695 6 the the DT cord-015369-72cjogxz 5695 7 surgical surgical JJ cord-015369-72cjogxz 5695 8 , , , cord-015369-72cjogxz 5695 9 histopathological histopathological JJ cord-015369-72cjogxz 5695 10 and and CC cord-015369-72cjogxz 5695 11 clinical clinical JJ cord-015369-72cjogxz 5695 12 records record NNS cord-015369-72cjogxz 5695 13 of of IN cord-015369-72cjogxz 5695 14 the the DT cord-015369-72cjogxz 5695 15 patients patient NNS cord-015369-72cjogxz 5695 16 . . . cord-015369-72cjogxz 5696 1 Results result NNS cord-015369-72cjogxz 5696 2 . . . cord-015369-72cjogxz 5697 1 Out out IN cord-015369-72cjogxz 5697 2 of of IN cord-015369-72cjogxz 5697 3 the the DT cord-015369-72cjogxz 5697 4 116 116 CD cord-015369-72cjogxz 5697 5 Patients patient NNS cord-015369-72cjogxz 5697 6 31 31 CD cord-015369-72cjogxz 5697 7 suffered suffer VBD cord-015369-72cjogxz 5697 8 from from IN cord-015369-72cjogxz 5697 9 an an DT cord-015369-72cjogxz 5697 10 intrahepatic intrahepatic JJ cord-015369-72cjogxz 5697 11 ( ( -LRB- cord-015369-72cjogxz 5697 12 27 27 CD cord-015369-72cjogxz 5697 13 % % NN cord-015369-72cjogxz 5697 14 ) ) -RRB- cord-015369-72cjogxz 5697 15 , , , cord-015369-72cjogxz 5697 16 33 33 CD cord-015369-72cjogxz 5697 17 a a DT cord-015369-72cjogxz 5697 18 perihilar perihilar NN cord-015369-72cjogxz 5697 19 ( ( -LRB- cord-015369-72cjogxz 5697 20 28 28 CD cord-015369-72cjogxz 5697 21 % % NN cord-015369-72cjogxz 5697 22 ) ) -RRB- cord-015369-72cjogxz 5697 23 and and CC cord-015369-72cjogxz 5697 24 52 52 CD cord-015369-72cjogxz 5697 25 a a DT cord-015369-72cjogxz 5697 26 distal distal JJ cord-015369-72cjogxz 5697 27 CCC CCC NNP cord-015369-72cjogxz 5697 28 ( ( -LRB- cord-015369-72cjogxz 5697 29 45 45 CD cord-015369-72cjogxz 5697 30 % % NN cord-015369-72cjogxz 5697 31 ) ) -RRB- cord-015369-72cjogxz 5697 32 . . . cord-015369-72cjogxz 5698 1 The the DT cord-015369-72cjogxz 5698 2 overall overall JJ cord-015369-72cjogxz 5698 3 resectability resectability NN cord-015369-72cjogxz 5698 4 rate rate NN cord-015369-72cjogxz 5698 5 was be VBD cord-015369-72cjogxz 5698 6 53 53 CD cord-015369-72cjogxz 5698 7 % % NN cord-015369-72cjogxz 5698 8 ( ( -LRB- cord-015369-72cjogxz 5698 9 51 51 CD cord-015369-72cjogxz 5698 10 % % NN cord-015369-72cjogxz 5698 11 intrahepatic intrahepatic JJ cord-015369-72cjogxz 5698 12 , , , cord-015369-72cjogxz 5698 13 27 27 CD cord-015369-72cjogxz 5698 14 % % NN cord-015369-72cjogxz 5698 15 perihilar perihilar NN cord-015369-72cjogxz 5698 16 and and CC cord-015369-72cjogxz 5698 17 78 78 CD cord-015369-72cjogxz 5698 18 % % NN cord-015369-72cjogxz 5698 19 distal distal JJ cord-015369-72cjogxz 5698 20 ) ) -RRB- cord-015369-72cjogxz 5698 21 . . . cord-015369-72cjogxz 5699 1 The the DT cord-015369-72cjogxz 5699 2 overall overall JJ cord-015369-72cjogxz 5699 3 perioperative perioperative JJ cord-015369-72cjogxz 5699 4 mortality mortality NN cord-015369-72cjogxz 5699 5 rate rate NN cord-015369-72cjogxz 5699 6 was be VBD cord-015369-72cjogxz 5699 7 17 17 CD cord-015369-72cjogxz 5699 8 % % NN cord-015369-72cjogxz 5699 9 ( ( -LRB- cord-015369-72cjogxz 5699 10 11 11 CD cord-015369-72cjogxz 5699 11 % % NN cord-015369-72cjogxz 5699 12 , , , cord-015369-72cjogxz 5699 13 21 21 CD cord-015369-72cjogxz 5699 14 % % NN cord-015369-72cjogxz 5699 15 and and CC cord-015369-72cjogxz 5699 16 15 15 CD cord-015369-72cjogxz 5699 17 % % NN cord-015369-72cjogxz 5699 18 respectively respectively RB cord-015369-72cjogxz 5699 19 ) ) -RRB- cord-015369-72cjogxz 5699 20 . . . cord-015369-72cjogxz 5700 1 The the DT cord-015369-72cjogxz 5700 2 1- 1- NNP cord-015369-72cjogxz 5700 3 , , , cord-015369-72cjogxz 5700 4 3-and 3-and CD cord-015369-72cjogxz 5700 5 5-year 5-year CD cord-015369-72cjogxz 5700 6 survival survival NN cord-015369-72cjogxz 5700 7 rates rate NNS cord-015369-72cjogxz 5700 8 in in IN cord-015369-72cjogxz 5700 9 all all DT cord-015369-72cjogxz 5700 10 groups group NNS cord-015369-72cjogxz 5700 11 after after IN cord-015369-72cjogxz 5700 12 curative curative JJ cord-015369-72cjogxz 5700 13 resection resection NN cord-015369-72cjogxz 5700 14 were be VBD cord-015369-72cjogxz 5700 15 73 73 CD cord-015369-72cjogxz 5700 16 % % NN cord-015369-72cjogxz 5700 17 , , , cord-015369-72cjogxz 5700 18 71 71 CD cord-015369-72cjogxz 5700 19 % % NN cord-015369-72cjogxz 5700 20 and and CC cord-015369-72cjogxz 5700 21 60 60 CD cord-015369-72cjogxz 5700 22 % % NN cord-015369-72cjogxz 5700 23 ; ; : cord-015369-72cjogxz 5700 24 20 20 CD cord-015369-72cjogxz 5700 25 % % NN cord-015369-72cjogxz 5700 26 , , , cord-015369-72cjogxz 5700 27 35 35 CD cord-015369-72cjogxz 5700 28 % % NN cord-015369-72cjogxz 5700 29 and and CC cord-015369-72cjogxz 5700 30 15 15 CD cord-015369-72cjogxz 5700 31 % % NN cord-015369-72cjogxz 5700 32 ; ; , cord-015369-72cjogxz 5700 33 and and CC cord-015369-72cjogxz 5700 34 finally finally RB cord-015369-72cjogxz 5700 35 13 13 CD cord-015369-72cjogxz 5700 36 % % NN cord-015369-72cjogxz 5700 37 , , , cord-015369-72cjogxz 5700 38 14 14 CD cord-015369-72cjogxz 5700 39 % % NN cord-015369-72cjogxz 5700 40 and and CC cord-015369-72cjogxz 5700 41 10 10 CD cord-015369-72cjogxz 5700 42 % % NN cord-015369-72cjogxz 5700 43 . . . cord-015369-72cjogxz 5701 1 The the DT cord-015369-72cjogxz 5701 2 overall overall JJ cord-015369-72cjogxz 5701 3 recurrence recurrence NN cord-015369-72cjogxz 5701 4 rate rate NN cord-015369-72cjogxz 5701 5 was be VBD cord-015369-72cjogxz 5701 6 61 61 CD cord-015369-72cjogxz 5701 7 % % NN cord-015369-72cjogxz 5701 8 . . . cord-015369-72cjogxz 5702 1 Conclusions conclusion NNS cord-015369-72cjogxz 5702 2 . . . cord-015369-72cjogxz 5703 1 Cholangiocarcinoma Cholangiocarcinoma NNP cord-015369-72cjogxz 5703 2 is be VBZ cord-015369-72cjogxz 5703 3 a a DT cord-015369-72cjogxz 5703 4 malign malign JJ cord-015369-72cjogxz 5703 5 tumor tumor NN cord-015369-72cjogxz 5703 6 disease disease NN cord-015369-72cjogxz 5703 7 with with IN cord-015369-72cjogxz 5703 8 poor poor JJ cord-015369-72cjogxz 5703 9 prognosis prognosis NN cord-015369-72cjogxz 5703 10 . . . cord-015369-72cjogxz 5704 1 Tumor tumor NN cord-015369-72cjogxz 5704 2 location location NN cord-015369-72cjogxz 5704 3 has have VBZ cord-015369-72cjogxz 5704 4 a a DT cord-015369-72cjogxz 5704 5 decisive decisive JJ cord-015369-72cjogxz 5704 6 influence influence NN cord-015369-72cjogxz 5704 7 on on IN cord-015369-72cjogxz 5704 8 the the DT cord-015369-72cjogxz 5704 9 resectability resectability NN cord-015369-72cjogxz 5704 10 rate rate NN cord-015369-72cjogxz 5704 11 and and CC cord-015369-72cjogxz 5704 12 determines determine VBZ cord-015369-72cjogxz 5704 13 therefore therefore RB cord-015369-72cjogxz 5704 14 the the DT cord-015369-72cjogxz 5704 15 prognosis prognosis NN cord-015369-72cjogxz 5704 16 of of IN cord-015369-72cjogxz 5704 17 the the DT cord-015369-72cjogxz 5704 18 patient patient NN cord-015369-72cjogxz 5704 19 . . . cord-015369-72cjogxz 5705 1 However however RB cord-015369-72cjogxz 5705 2 , , , cord-015369-72cjogxz 5705 3 when when WRB cord-015369-72cjogxz 5705 4 resectability resectability NN cord-015369-72cjogxz 5705 5 is be VBZ cord-015369-72cjogxz 5705 6 provided provide VBN cord-015369-72cjogxz 5705 7 in in IN cord-015369-72cjogxz 5705 8 all all DT cord-015369-72cjogxz 5705 9 groups group NNS cord-015369-72cjogxz 5705 10 , , , cord-015369-72cjogxz 5705 11 location location NN cord-015369-72cjogxz 5705 12 has have VBZ cord-015369-72cjogxz 5705 13 no no DT cord-015369-72cjogxz 5705 14 effect effect NN cord-015369-72cjogxz 5705 15 on on IN cord-015369-72cjogxz 5705 16 the the DT cord-015369-72cjogxz 5705 17 prognosis prognosis NN cord-015369-72cjogxz 5705 18 . . . cord-015369-72cjogxz 5706 1 Das Das NNP cord-015369-72cjogxz 5706 2 J123-Ganzkörperszintigramm J123-Ganzkörperszintigramm NNP cord-015369-72cjogxz 5707 1 ( ( -LRB- cord-015369-72cjogxz 5707 2 GK GK NNP cord-015369-72cjogxz 5707 3 ) ) -RRB- cord-015369-72cjogxz 5707 4 ergab ergab VBD cord-015369-72cjogxz 5707 5 multiple multiple JJ cord-015369-72cjogxz 5707 6 Speicherungen Speicherungen NNP cord-015369-72cjogxz 5707 7 in in IN cord-015369-72cjogxz 5707 8 der der NNP cord-015369-72cjogxz 5707 9 SD SD NNP cord-015369-72cjogxz 5707 10 - - HYPH cord-015369-72cjogxz 5707 11 Loge Loge NNP cord-015369-72cjogxz 5707 12 und und IN cord-015369-72cjogxz 5707 13 der der NNP cord-015369-72cjogxz 5707 14 oberen oberen NNP cord-015369-72cjogxz 5707 15 Thoraxapertur Thoraxapertur NNP cord-015369-72cjogxz 5707 16 , , , cord-015369-72cjogxz 5707 17 einem einem NNP cord-015369-72cjogxz 5707 18 Rezidiv Rezidiv NNP cord-015369-72cjogxz 5707 19 entsprechend entsprechend NN cord-015369-72cjogxz 5707 20 . . . cord-015369-72cjogxz 5708 1 Weiters Weiters NNP cord-015369-72cjogxz 5708 2 wurden wurden XX cord-015369-72cjogxz 5709 1 i -PRON- PRP cord-015369-72cjogxz 5709 2 m be VBP cord-015369-72cjogxz 5709 3 Abdomen Abdomen NNP cord-015369-72cjogxz 5709 4 mehrere mehrere NNP cord-015369-72cjogxz 5709 5 Speicherherde Speicherherde NNP cord-015369-72cjogxz 5709 6 erkannt erkannt NNP cord-015369-72cjogxz 5709 7 , , , cord-015369-72cjogxz 5709 8 die die VBP cord-015369-72cjogxz 5709 9 sich sich NNP cord-015369-72cjogxz 5709 10 i -PRON- PRP cord-015369-72cjogxz 5709 11 m be VBP cord-015369-72cjogxz 5709 12 SPECT SPECT NNP cord-015369-72cjogxz 5709 13 / / SYM cord-015369-72cjogxz 5709 14 CT CT NNP cord-015369-72cjogxz 5709 15 in in IN cord-015369-72cjogxz 5709 16 der der NNP cord-015369-72cjogxz 5709 17 Leber Leber NNP cord-015369-72cjogxz 5709 18 lokalisieren lokalisieren NNP cord-015369-72cjogxz 5709 19 ließen ließen NNP cord-015369-72cjogxz 5709 20 . . . cord-015369-72cjogxz 5710 1 Die die VB cord-015369-72cjogxz 5711 1 Sonographie Sonographie NNP cord-015369-72cjogxz 5711 2 bestätigte bestätigte NN cord-015369-72cjogxz 5711 3 den den NNP cord-015369-72cjogxz 5711 4 Verdacht Verdacht NNP cord-015369-72cjogxz 5711 5 auf auf NNP cord-015369-72cjogxz 5711 6 Lebermetastasen Lebermetastasen NNP cord-015369-72cjogxz 5711 7 und und IN cord-015369-72cjogxz 5711 8 auf auf NNP cord-015369-72cjogxz 5711 9 einen einen NNP cord-015369-72cjogxz 5711 10 weiteren weiteren NNP cord-015369-72cjogxz 5711 11 , , , cord-015369-72cjogxz 5712 1 paracaval paracaval NNP cord-015369-72cjogxz 5712 2 liegenden liegenden NNP cord-015369-72cjogxz 5712 3 Herd Herd NNP cord-015369-72cjogxz 5712 4 ( ( -LRB- cord-015369-72cjogxz 5712 5 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 5712 6 ) ) -RRB- cord-015369-72cjogxz 5712 7 . . . cord-015369-72cjogxz 5713 1 Aufgrund Aufgrund NNP cord-015369-72cjogxz 5713 2 des des FW cord-015369-72cjogxz 5713 3 massiv massiv NN cord-015369-72cjogxz 5714 1 erhöhten erhöhten NNP cord-015369-72cjogxz 5714 2 Tg Tg NNP cord-015369-72cjogxz 5714 3 - - HYPH cord-015369-72cjogxz 5714 4 Wertes Wertes NNP cord-015369-72cjogxz 5714 5 und und IN cord-015369-72cjogxz 5714 6 der der NNP cord-015369-72cjogxz 5714 7 deutlichen deutlichen NNP cord-015369-72cjogxz 5714 8 Speicherung Speicherung NNP cord-015369-72cjogxz 5715 1 i -PRON- PRP cord-015369-72cjogxz 5715 2 m be VBP cord-015369-72cjogxz 5715 3 123J 123j CD cord-015369-72cjogxz 5716 1 -GK -gk UH cord-015369-72cjogxz 5716 2 - - JJ cord-015369-72cjogxz 5716 3 Scan scan JJ cord-015369-72cjogxz 5716 4 wurde wurde NN cord-015369-72cjogxz 5716 5 eine eine NNP cord-015369-72cjogxz 5716 6 weitere weitere JJ cord-015369-72cjogxz 5716 7 hochdosierte hochdosierte NNP cord-015369-72cjogxz 5716 8 RJT RJT NNP cord-015369-72cjogxz 5716 9 ( ( -LRB- cord-015369-72cjogxz 5716 10 7800 7800 CD cord-015369-72cjogxz 5716 11 MBq MBq NNS cord-015369-72cjogxz 5716 12 ) ) -RRB- cord-015369-72cjogxz 5717 1 unter unter JJ cord-015369-72cjogxz 5717 2 exogener exogen JJR cord-015369-72cjogxz 5717 3 TSH TSH NNP cord-015369-72cjogxz 5717 4 - - HYPH cord-015369-72cjogxz 5717 5 Stimulation stimulation NN cord-015369-72cjogxz 5717 6 veranlasst veranlasst NN cord-015369-72cjogxz 5717 7 . . . cord-015369-72cjogxz 5718 1 Posttherapeutisch Posttherapeutisch NNP cord-015369-72cjogxz 5718 2 fanden fanden NNP cord-015369-72cjogxz 5718 3 sich sich NNP cord-015369-72cjogxz 5718 4 analog analog NNP cord-015369-72cjogxz 5719 1 zum zum NNP cord-015369-72cjogxz 5719 2 diagnostischen diagnostischen NNP cord-015369-72cjogxz 5720 1 Jod Jod NNP cord-015369-72cjogxz 5720 2 - - HYPH cord-015369-72cjogxz 5720 3 Scan scan JJ cord-015369-72cjogxz 5720 4 deutliche deutliche NN cord-015369-72cjogxz 5721 1 Anreicherungen Anreicherungen NNP cord-015369-72cjogxz 5722 1 i -PRON- PRP cord-015369-72cjogxz 5722 2 m be VBP cord-015369-72cjogxz 5723 1 Hals Hals NNP cord-015369-72cjogxz 5723 2 - - HYPH cord-015369-72cjogxz 5723 3 und und NNP cord-015369-72cjogxz 5724 1 Abdomen Abdomen NNP cord-015369-72cjogxz 5725 1 i i PRP cord-015369-72cjogxz 5726 1 m m LS cord-015369-72cjogxz 5727 1 Sinne Sinne NNP cord-015369-72cjogxz 5727 2 von von NNP cord-015369-72cjogxz 5727 3 Jod Jod NNP cord-015369-72cjogxz 5727 4 - - HYPH cord-015369-72cjogxz 5727 5 aviden aviden NNP cord-015369-72cjogxz 5727 6 Speicherherden Speicherherden NNP cord-015369-72cjogxz 5727 7 . . . cord-015369-72cjogxz 5728 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 5728 2 . . . cord-015369-72cjogxz 5729 1 Dieser Dieser NNP cord-015369-72cjogxz 5729 2 Fallbericht Fallbericht NNP cord-015369-72cjogxz 5729 3 demonstriert demonstriert NN cord-015369-72cjogxz 5729 4 , , , cord-015369-72cjogxz 5729 5 dass dass NNP cord-015369-72cjogxz 5729 6 bei bei NNP cord-015369-72cjogxz 5729 7 der der NNP cord-015369-72cjogxz 5729 8 Nachsorge Nachsorge NNP cord-015369-72cjogxz 5729 9 eines eines NNP cord-015369-72cjogxz 5729 10 FTC FTC NNP cord-015369-72cjogxz 5730 1 an an DT cord-015369-72cjogxz 5730 2 sehr sehr JJ cord-015369-72cjogxz 5730 3 selten selten NNP cord-015369-72cjogxz 5730 4 vorkommende vorkommende NNP cord-015369-72cjogxz 5731 1 Tumorlokalisationen Tumorlokalisationen NNP cord-015369-72cjogxz 5731 2 wie wie NNP cord-015369-72cjogxz 5731 3 Lebermetastasen Lebermetastasen NNP cord-015369-72cjogxz 5731 4 gedacht gedacht NNP cord-015369-72cjogxz 5731 5 werden werden NNP cord-015369-72cjogxz 5731 6 sollte sollte NNP cord-015369-72cjogxz 5731 7 . . . cord-015369-72cjogxz 5732 1 Zum Zum NNP cord-015369-72cjogxz 5732 2 anderen anderen NNP cord-015369-72cjogxz 5732 3 zeigt zeigt NNP cord-015369-72cjogxz 5732 4 dieser dieser NNP cord-015369-72cjogxz 5732 5 Fall Fall NNP cord-015369-72cjogxz 5732 6 auch auch NNP cord-015369-72cjogxz 5732 7 , , , cord-015369-72cjogxz 5732 8 dass dass NNP cord-015369-72cjogxz 5732 9 anatomische anatomische NNP cord-015369-72cjogxz 5732 10 Besonderheiten Besonderheiten NNP cord-015369-72cjogxz 5733 1 i i PRP cord-015369-72cjogxz 5734 1 m m NNP cord-015369-72cjogxz 5734 2 Rahmen Rahmen NNP cord-015369-72cjogxz 5734 3 medizinischer medizinischer NNP cord-015369-72cjogxz 5735 1 Interventionen Interventionen NNP cord-015369-72cjogxz 5735 2 ( ( -LRB- cord-015369-72cjogxz 5735 3 z. z. NNP cord-015369-72cjogxz 5736 1 B. B. NNP cord-015369-72cjogxz 5736 2 Tracheostoma Tracheostoma NNP cord-015369-72cjogxz 5736 3 , , , cord-015369-72cjogxz 5736 4 PEG PEG NNP cord-015369-72cjogxz 5736 5 - - HYPH cord-015369-72cjogxz 5736 6 Sonden Sonden NNP cord-015369-72cjogxz 5736 7 , , , cord-015369-72cjogxz 5736 8 div div NNP cord-015369-72cjogxz 5736 9 . . . cord-015369-72cjogxz 5737 1 Katheter Katheter NNP cord-015369-72cjogxz 5737 2 , , , cord-015369-72cjogxz 5737 3 etc etc FW cord-015369-72cjogxz 5737 4 . . . cord-015369-72cjogxz 5737 5 ) ) -RRB- cord-015369-72cjogxz 5737 6 , , , cord-015369-72cjogxz 5737 7 pathologische pathologische NNP cord-015369-72cjogxz 5737 8 Speicherungen Speicherungen NNP cord-015369-72cjogxz 5737 9 maskieren maskieren NNP cord-015369-72cjogxz 5737 10 können können NNP cord-015369-72cjogxz 5737 11 . . . cord-015369-72cjogxz 5738 1 Hier Hier NNP cord-015369-72cjogxz 5738 2 stellt stellt NNP cord-015369-72cjogxz 5738 3 die die VBP cord-015369-72cjogxz 5739 1 anatomisch anatomisch NNP cord-015369-72cjogxz 5739 2 / / SYM cord-015369-72cjogxz 5739 3 metabolische metabolische NN cord-015369-72cjogxz 5739 4 Bildgebung Bildgebung NNP cord-015369-72cjogxz 5739 5 mittels mittels NNP cord-015369-72cjogxz 5739 6 SPECT SPECT NNP cord-015369-72cjogxz 5739 7 / / SYM cord-015369-72cjogxz 5739 8 CT CT NNP cord-015369-72cjogxz 5739 9 ein ein NNP cord-015369-72cjogxz 5739 10 probates probate NNS cord-015369-72cjogxz 5739 11 Mittel Mittel NNP cord-015369-72cjogxz 5740 1 für für NNP cord-015369-72cjogxz 5740 2 die die VBP cord-015369-72cjogxz 5740 3 Differentialdiagnose Differentialdiagnose NNP cord-015369-72cjogxz 5740 4 dar dar NNP cord-015369-72cjogxz 5740 5 . . . cord-015369-72cjogxz 5741 1 Chemotherapeutic chemotherapeutic JJ cord-015369-72cjogxz 5741 2 treatment treatment NN cord-015369-72cjogxz 5741 3 of of IN cord-015369-72cjogxz 5741 4 cancer cancer NN cord-015369-72cjogxz 5741 5 patients patient NNS cord-015369-72cjogxz 5741 6 is be VBZ cord-015369-72cjogxz 5741 7 aimed aim VBN cord-015369-72cjogxz 5741 8 at at IN cord-015369-72cjogxz 5741 9 eradication eradication NN cord-015369-72cjogxz 5741 10 of of IN cord-015369-72cjogxz 5741 11 the the DT cord-015369-72cjogxz 5741 12 tumor tumor NN cord-015369-72cjogxz 5741 13 . . . cord-015369-72cjogxz 5742 1 In in IN cord-015369-72cjogxz 5742 2 the the DT cord-015369-72cjogxz 5742 3 recent recent JJ cord-015369-72cjogxz 5742 4 years year NNS cord-015369-72cjogxz 5742 5 it -PRON- PRP cord-015369-72cjogxz 5742 6 became become VBD cord-015369-72cjogxz 5742 7 clear clear JJ cord-015369-72cjogxz 5742 8 that that IN cord-015369-72cjogxz 5742 9 also also RB cord-015369-72cjogxz 5742 10 the the DT cord-015369-72cjogxz 5742 11 immune immune JJ cord-015369-72cjogxz 5742 12 system system NN cord-015369-72cjogxz 5742 13 contributes contribute VBZ cord-015369-72cjogxz 5742 14 substantially substantially RB cord-015369-72cjogxz 5742 15 the the DT cord-015369-72cjogxz 5742 16 removal removal NN cord-015369-72cjogxz 5742 17 of of IN cord-015369-72cjogxz 5742 18 tumor tumor NN cord-015369-72cjogxz 5742 19 cells cell NNS cord-015369-72cjogxz 5742 20 . . . cord-015369-72cjogxz 5743 1 Tumor tumor NN cord-015369-72cjogxz 5743 2 infiltrating infiltrate VBG cord-015369-72cjogxz 5743 3 leukocytes leukocyte NNS cord-015369-72cjogxz 5743 4 , , , cord-015369-72cjogxz 5743 5 however however RB cord-015369-72cjogxz 5743 6 , , , cord-015369-72cjogxz 5743 7 are be VBP cord-015369-72cjogxz 5743 8 commonly commonly RB cord-015369-72cjogxz 5743 9 suppressed suppress VBN cord-015369-72cjogxz 5743 10 by by IN cord-015369-72cjogxz 5743 11 the the DT cord-015369-72cjogxz 5743 12 tumor tumor NN cord-015369-72cjogxz 5743 13 in in IN cord-015369-72cjogxz 5743 14 their -PRON- PRP$ cord-015369-72cjogxz 5743 15 function function NN cord-015369-72cjogxz 5743 16 which which WDT cord-015369-72cjogxz 5743 17 reduces reduce VBZ cord-015369-72cjogxz 5743 18 the the DT cord-015369-72cjogxz 5743 19 success success NN cord-015369-72cjogxz 5743 20 of of IN cord-015369-72cjogxz 5743 21 a a DT cord-015369-72cjogxz 5743 22 chemotherapeutic chemotherapeutic JJ cord-015369-72cjogxz 5743 23 treatment treatment NN cord-015369-72cjogxz 5743 24 . . . cord-015369-72cjogxz 5744 1 In in IN cord-015369-72cjogxz 5744 2 a a DT cord-015369-72cjogxz 5744 3 recently recently RB cord-015369-72cjogxz 5744 4 published publish VBN cord-015369-72cjogxz 5744 5 study study NN cord-015369-72cjogxz 5744 6 we -PRON- PRP cord-015369-72cjogxz 5744 7 demonstrated demonstrate VBD cord-015369-72cjogxz 5744 8 that that IN cord-015369-72cjogxz 5744 9 replication replication NN cord-015369-72cjogxz 5744 10 defective defective JJ cord-015369-72cjogxz 5744 11 Influenza Influenza NNP cord-015369-72cjogxz 5744 12 A A NNP cord-015369-72cjogxz 5744 13 vaccine vaccine NN cord-015369-72cjogxz 5744 14 virus virus NN cord-015369-72cjogxz 5744 15 mutant mutant NN cord-015369-72cjogxz 5744 16 delNS1 delNS1 NNS cord-015369-72cjogxz 5744 17 is be VBZ cord-015369-72cjogxz 5744 18 able able JJ cord-015369-72cjogxz 5744 19 to to TO cord-015369-72cjogxz 5744 20 boost boost VB cord-015369-72cjogxz 5744 21 the the DT cord-015369-72cjogxz 5744 22 cytotoxic cytotoxic JJ cord-015369-72cjogxz 5744 23 response response NN cord-015369-72cjogxz 5744 24 of of IN cord-015369-72cjogxz 5744 25 peripheral peripheral JJ cord-015369-72cjogxz 5744 26 blood blood NN cord-015369-72cjogxz 5744 27 mononuclear mononuclear NN cord-015369-72cjogxz 5744 28 cells cell NNS cord-015369-72cjogxz 5744 29 ( ( -LRB- cord-015369-72cjogxz 5744 30 PBMC PBMC NNP cord-015369-72cjogxz 5744 31 's 's POS cord-015369-72cjogxz 5744 32 ) ) -RRB- cord-015369-72cjogxz 5744 33 to to TO cord-015369-72cjogxz 5744 34 tumor tumor NN cord-015369-72cjogxz 5744 35 cells cell NNS cord-015369-72cjogxz 5744 36 '' '' '' cord-015369-72cjogxz 5745 1 in in FW cord-015369-72cjogxz 5745 2 vitro vitro FW cord-015369-72cjogxz 5745 3 ' ' '' cord-015369-72cjogxz 5745 4 ' ' '' cord-015369-72cjogxz 5745 5 . . . cord-015369-72cjogxz 5746 1 Here here RB cord-015369-72cjogxz 5746 2 we -PRON- PRP cord-015369-72cjogxz 5746 3 investigated investigate VBD cord-015369-72cjogxz 5746 4 whether whether IN cord-015369-72cjogxz 5746 5 such such PDT cord-015369-72cjogxz 5746 6 a a DT cord-015369-72cjogxz 5746 7 treatment treatment NN cord-015369-72cjogxz 5746 8 could could MD cord-015369-72cjogxz 5746 9 be be VB cord-015369-72cjogxz 5746 10 used use VBN cord-015369-72cjogxz 5746 11 to to TO cord-015369-72cjogxz 5746 12 overcome overcome VB cord-015369-72cjogxz 5746 13 an an DT cord-015369-72cjogxz 5746 14 immunosuppressive immunosuppressive JJ cord-015369-72cjogxz 5746 15 state state NN cord-015369-72cjogxz 5746 16 of of IN cord-015369-72cjogxz 5746 17 PBMC PBMC NNP cord-015369-72cjogxz 5746 18 's 's POS cord-015369-72cjogxz 5746 19 . . . cord-015369-72cjogxz 5747 1 PBMC PBMC NNP cord-015369-72cjogxz 5747 2 's 's POS cord-015369-72cjogxz 5747 3 from from IN cord-015369-72cjogxz 5747 4 3 3 CD cord-015369-72cjogxz 5747 5 healthy healthy JJ cord-015369-72cjogxz 5747 6 volunteers volunteer NNS cord-015369-72cjogxz 5747 7 were be VBD cord-015369-72cjogxz 5747 8 treated treat VBN cord-015369-72cjogxz 5747 9 with with IN cord-015369-72cjogxz 5747 10 LPS LPS NNP cord-015369-72cjogxz 5747 11 for for IN cord-015369-72cjogxz 5747 12 24 24 CD cord-015369-72cjogxz 5747 13 h. h. NN cord-015369-72cjogxz 5748 1 This this DT cord-015369-72cjogxz 5748 2 is be VBZ cord-015369-72cjogxz 5748 3 known know VBN cord-015369-72cjogxz 5748 4 to to TO cord-015369-72cjogxz 5748 5 promote promote VB cord-015369-72cjogxz 5748 6 formation formation NN cord-015369-72cjogxz 5748 7 of of IN cord-015369-72cjogxz 5748 8 unreactive unreactive JJ cord-015369-72cjogxz 5748 9 M2-Macrophages m2-macrophage NNS cord-015369-72cjogxz 5748 10 . . . cord-015369-72cjogxz 5749 1 Then then RB cord-015369-72cjogxz 5749 2 those those DT cord-015369-72cjogxz 5749 3 PBMC PBMC NNP cord-015369-72cjogxz 5749 4 's 's POS cord-015369-72cjogxz 5749 5 where where WRB cord-015369-72cjogxz 5749 6 added add VBN cord-015369-72cjogxz 5749 7 to to IN cord-015369-72cjogxz 5749 8 MCF-7 MCF-7 NNP cord-015369-72cjogxz 5749 9 and and CC cord-015369-72cjogxz 5749 10 PANC1 PANC1 NNP cord-015369-72cjogxz 5749 11 tumor tumor NN cord-015369-72cjogxz 5749 12 cells cell NNS cord-015369-72cjogxz 5749 13 in in IN cord-015369-72cjogxz 5749 14 presence presence NN cord-015369-72cjogxz 5749 15 or or CC cord-015369-72cjogxz 5749 16 absence absence NN cord-015369-72cjogxz 5749 17 of of IN cord-015369-72cjogxz 5749 18 chemotherapeutic chemotherapeutic JJ cord-015369-72cjogxz 5749 19 drugs drug NNS cord-015369-72cjogxz 5749 20 ( ( -LRB- cord-015369-72cjogxz 5749 21 Gemcitabine Gemcitabine NNP cord-015369-72cjogxz 5749 22 and and CC cord-015369-72cjogxz 5749 23 Cisplatin Cisplatin NNP cord-015369-72cjogxz 5749 24 ) ) -RRB- cord-015369-72cjogxz 5749 25 . . . cord-015369-72cjogxz 5750 1 LPS LPS NNP cord-015369-72cjogxz 5750 2 - - HYPH cord-015369-72cjogxz 5750 3 treated treat VBN cord-015369-72cjogxz 5750 4 PBMC PBMC NNP cord-015369-72cjogxz 5750 5 's 's POS cord-015369-72cjogxz 5750 6 showed show VBD cord-015369-72cjogxz 5750 7 a a DT cord-015369-72cjogxz 5750 8 significant significant JJ cord-015369-72cjogxz 5750 9 lower low JJR cord-015369-72cjogxz 5750 10 cytotoxic cytotoxic JJ cord-015369-72cjogxz 5750 11 effect effect NN cord-015369-72cjogxz 5750 12 on on IN cord-015369-72cjogxz 5750 13 tumor tumor NN cord-015369-72cjogxz 5750 14 cells cell NNS cord-015369-72cjogxz 5750 15 in in IN cord-015369-72cjogxz 5750 16 comparison comparison NN cord-015369-72cjogxz 5750 17 to to IN cord-015369-72cjogxz 5750 18 untreated untreated JJ cord-015369-72cjogxz 5750 19 cells cell NNS cord-015369-72cjogxz 5750 20 . . . cord-015369-72cjogxz 5751 1 This this DT cord-015369-72cjogxz 5751 2 effect effect NN cord-015369-72cjogxz 5751 3 was be VBD cord-015369-72cjogxz 5751 4 detectable detectable JJ cord-015369-72cjogxz 5751 5 with with IN cord-015369-72cjogxz 5751 6 and and CC cord-015369-72cjogxz 5751 7 without without IN cord-015369-72cjogxz 5751 8 chemotherapy chemotherapy NN cord-015369-72cjogxz 5751 9 . . . cord-015369-72cjogxz 5752 1 Pre pre JJ cord-015369-72cjogxz 5752 2 - - NN cord-015369-72cjogxz 5752 3 incubation incubation JJ cord-015369-72cjogxz 5752 4 with with IN cord-015369-72cjogxz 5752 5 delNS1 delNS1 NNS cord-015369-72cjogxz 5752 6 boosted boost VBD cord-015369-72cjogxz 5752 7 the the DT cord-015369-72cjogxz 5752 8 cytotoxic cytotoxic JJ cord-015369-72cjogxz 5752 9 capacity capacity NN cord-015369-72cjogxz 5752 10 of of IN cord-015369-72cjogxz 5752 11 PBMC PBMC NNP cord-015369-72cjogxz 5752 12 's 's POS cord-015369-72cjogxz 5752 13 and and CC cord-015369-72cjogxz 5752 14 abolished abolish VBD cord-015369-72cjogxz 5752 15 the the DT cord-015369-72cjogxz 5752 16 effect effect NN cord-015369-72cjogxz 5752 17 of of IN cord-015369-72cjogxz 5752 18 LPS LPS NNP cord-015369-72cjogxz 5752 19 - - HYPH cord-015369-72cjogxz 5752 20 pretreatment pretreatment NN cord-015369-72cjogxz 5752 21 . . . cord-015369-72cjogxz 5753 1 These these DT cord-015369-72cjogxz 5753 2 data datum NNS cord-015369-72cjogxz 5753 3 indicate indicate VBP cord-015369-72cjogxz 5753 4 that that IN cord-015369-72cjogxz 5753 5 pretreatment pretreatment NN cord-015369-72cjogxz 5753 6 of of IN cord-015369-72cjogxz 5753 7 patients patient NNS cord-015369-72cjogxz 5753 8 leukocytes leukocyte NNS cord-015369-72cjogxz 5753 9 with with IN cord-015369-72cjogxz 5753 10 delNS1 delNS1 NNS cord-015369-72cjogxz 5753 11 might may MD cord-015369-72cjogxz 5753 12 be be VB cord-015369-72cjogxz 5753 13 useful useful JJ cord-015369-72cjogxz 5753 14 to to TO cord-015369-72cjogxz 5753 15 increase increase VB cord-015369-72cjogxz 5753 16 the the DT cord-015369-72cjogxz 5753 17 effect effect NN cord-015369-72cjogxz 5753 18 of of IN cord-015369-72cjogxz 5753 19 chemotherapy chemotherapy NN cord-015369-72cjogxz 5753 20 . . . cord-015369-72cjogxz 5754 1 Background background NN cord-015369-72cjogxz 5754 2 . . . cord-015369-72cjogxz 5755 1 Pancreatic pancreatic JJ cord-015369-72cjogxz 5755 2 necrosis necrosis NN cord-015369-72cjogxz 5755 3 is be VBZ cord-015369-72cjogxz 5755 4 a a DT cord-015369-72cjogxz 5755 5 serious serious JJ cord-015369-72cjogxz 5755 6 complication complication NN cord-015369-72cjogxz 5755 7 of of IN cord-015369-72cjogxz 5755 8 acute acute JJ cord-015369-72cjogxz 5755 9 pancreatitis pancreatitis NN cord-015369-72cjogxz 5755 10 . . . cord-015369-72cjogxz 5756 1 The the DT cord-015369-72cjogxz 5756 2 identification identification NN cord-015369-72cjogxz 5756 3 of of IN cord-015369-72cjogxz 5756 4 laboratory laboratory NN cord-015369-72cjogxz 5756 5 tests test NNS cord-015369-72cjogxz 5756 6 to to TO cord-015369-72cjogxz 5756 7 detect detect VB cord-015369-72cjogxz 5756 8 subjects subject NNS cord-015369-72cjogxz 5756 9 at at IN cord-015369-72cjogxz 5756 10 risk risk NN cord-015369-72cjogxz 5756 11 of of IN cord-015369-72cjogxz 5756 12 pancreatic pancreatic JJ cord-015369-72cjogxz 5756 13 necrosis necrosis NN cord-015369-72cjogxz 5756 14 may may MD cord-015369-72cjogxz 5756 15 direct direct VB cord-015369-72cjogxz 5756 16 management management NN cord-015369-72cjogxz 5756 17 and and CC cord-015369-72cjogxz 5756 18 improve improve VB cord-015369-72cjogxz 5756 19 outcome outcome NN cord-015369-72cjogxz 5756 20 . . . cord-015369-72cjogxz 5757 1 Soluble soluble JJ cord-015369-72cjogxz 5757 2 thrombomodulin thrombomodulin NNP cord-015369-72cjogxz 5757 3 ( ( -LRB- cord-015369-72cjogxz 5757 4 sTM sTM NNP cord-015369-72cjogxz 5757 5 ) ) -RRB- cord-015369-72cjogxz 5757 6 has have VBZ cord-015369-72cjogxz 5757 7 been be VBN cord-015369-72cjogxz 5757 8 identified identify VBN cord-015369-72cjogxz 5757 9 as as IN cord-015369-72cjogxz 5757 10 a a DT cord-015369-72cjogxz 5757 11 marker marker NN cord-015369-72cjogxz 5757 12 of of IN cord-015369-72cjogxz 5757 13 poor poor JJ cord-015369-72cjogxz 5757 14 prognosis prognosis NN cord-015369-72cjogxz 5757 15 in in IN cord-015369-72cjogxz 5757 16 the the DT cord-015369-72cjogxz 5757 17 critically critically RB cord-015369-72cjogxz 5757 18 ill ill JJ cord-015369-72cjogxz 5757 19 . . . cord-015369-72cjogxz 5758 1 Circulating circulate VBG cord-015369-72cjogxz 5758 2 ( ( -LRB- cord-015369-72cjogxz 5758 3 cell cell NN cord-015369-72cjogxz 5758 4 - - HYPH cord-015369-72cjogxz 5758 5 free free JJ cord-015369-72cjogxz 5758 6 ) ) -RRB- cord-015369-72cjogxz 5758 7 DNA dna NN cord-015369-72cjogxz 5758 8 in in IN cord-015369-72cjogxz 5758 9 serum serum NN cord-015369-72cjogxz 5758 10 or or CC cord-015369-72cjogxz 5758 11 plasma plasma NN cord-015369-72cjogxz 5758 12 has have VBZ cord-015369-72cjogxz 5758 13 been be VBN cord-015369-72cjogxz 5758 14 investigated investigate VBN cord-015369-72cjogxz 5758 15 as as IN cord-015369-72cjogxz 5758 16 a a DT cord-015369-72cjogxz 5758 17 non non JJ cord-015369-72cjogxz 5758 18 - - JJ cord-015369-72cjogxz 5758 19 invasive invasive JJ cord-015369-72cjogxz 5758 20 diagnostic diagnostic JJ cord-015369-72cjogxz 5758 21 tool tool NN cord-015369-72cjogxz 5758 22 in in IN cord-015369-72cjogxz 5758 23 a a DT cord-015369-72cjogxz 5758 24 variety variety NN cord-015369-72cjogxz 5758 25 of of IN cord-015369-72cjogxz 5758 26 clinical clinical JJ cord-015369-72cjogxz 5758 27 conditions condition NNS cord-015369-72cjogxz 5758 28 . . . cord-015369-72cjogxz 5759 1 Methods method NNS cord-015369-72cjogxz 5759 2 . . . cord-015369-72cjogxz 5760 1 We -PRON- PRP cord-015369-72cjogxz 5760 2 studied study VBD cord-015369-72cjogxz 5760 3 44 44 CD cord-015369-72cjogxz 5760 4 patients patient NNS cord-015369-72cjogxz 5760 5 with with IN cord-015369-72cjogxz 5760 6 acute acute JJ cord-015369-72cjogxz 5760 7 pancreatitis pancreatitis NN cord-015369-72cjogxz 5760 8 ( ( -LRB- cord-015369-72cjogxz 5760 9 18 18 CD cord-015369-72cjogxz 5760 10 -mild -mild SYM cord-015369-72cjogxz 5760 11 , , , cord-015369-72cjogxz 5760 12 26 26 CD cord-015369-72cjogxz 5760 13 -severe -severe NN cord-015369-72cjogxz 5760 14 ) ) -RRB- cord-015369-72cjogxz 5760 15 . . . cord-015369-72cjogxz 5761 1 A a DT cord-015369-72cjogxz 5761 2 thrombomodulin thrombomodulin NN cord-015369-72cjogxz 5761 3 level level NN cord-015369-72cjogxz 5761 4 was be VBD cord-015369-72cjogxz 5761 5 determined determine VBN cord-015369-72cjogxz 5761 6 by by IN cord-015369-72cjogxz 5761 7 ELISA ELISA NNP cord-015369-72cjogxz 5761 8 . . . cord-015369-72cjogxz 5762 1 Serum serum NN cord-015369-72cjogxz 5762 2 creatinine creatinine NN cord-015369-72cjogxz 5762 3 was be VBD cord-015369-72cjogxz 5762 4 analyzed analyze VBN cord-015369-72cjogxz 5762 5 on on IN cord-015369-72cjogxz 5762 6 Biochemical Biochemical NNP cord-015369-72cjogxz 5762 7 Analyzer Analyzer NNP cord-015369-72cjogxz 5762 8 . . . cord-015369-72cjogxz 5763 1 DNA DNA NNP cord-015369-72cjogxz 5763 2 was be VBD cord-015369-72cjogxz 5763 3 calculated calculate VBN cord-015369-72cjogxz 5763 4 by by IN cord-015369-72cjogxz 5763 5 real real JJ cord-015369-72cjogxz 5763 6 time time NN cord-015369-72cjogxz 5763 7 PCR PCR NNP cord-015369-72cjogxz 5763 8 . . . cord-015369-72cjogxz 5764 1 The the DT cord-015369-72cjogxz 5764 2 degree degree NN cord-015369-72cjogxz 5764 3 of of IN cord-015369-72cjogxz 5764 4 pancreatic pancreatic JJ cord-015369-72cjogxz 5764 5 necrosis necrosis NN cord-015369-72cjogxz 5764 6 was be VBD cord-015369-72cjogxz 5764 7 classified classify VBN cord-015369-72cjogxz 5764 8 by by IN cord-015369-72cjogxz 5764 9 CT CT NNP cord-015369-72cjogxz 5764 10 Balthazar Balthazar NNP cord-015369-72cjogxz 5764 11 criterion criterion NN cord-015369-72cjogxz 5764 12 . . . cord-015369-72cjogxz 5765 1 Results result NNS cord-015369-72cjogxz 5765 2 . . . cord-015369-72cjogxz 5766 1 The the DT cord-015369-72cjogxz 5766 2 levels level NNS cord-015369-72cjogxz 5766 3 TM TM NNP cord-015369-72cjogxz 5766 4 , , , cord-015369-72cjogxz 5766 5 free free JJ cord-015369-72cjogxz 5766 6 DNA dna NN cord-015369-72cjogxz 5766 7 and and CC cord-015369-72cjogxz 5766 8 creatinine creatinine NN cord-015369-72cjogxz 5766 9 of of IN cord-015369-72cjogxz 5766 10 the the DT cord-015369-72cjogxz 5766 11 severe severe JJ cord-015369-72cjogxz 5766 12 acute acute JJ cord-015369-72cjogxz 5766 13 pancreatitis pancreatitis NN cord-015369-72cjogxz 5766 14 group group NN cord-015369-72cjogxz 5766 15 were be VBD cord-015369-72cjogxz 5766 16 significantly significantly RB cord-015369-72cjogxz 5766 17 higher high JJR cord-015369-72cjogxz 5766 18 . . . cord-015369-72cjogxz 5767 1 Free free JJ cord-015369-72cjogxz 5767 2 serum serum NN cord-015369-72cjogxz 5767 3 DNA dna NN cord-015369-72cjogxz 5767 4 was be VBD cord-015369-72cjogxz 5767 5 in in IN cord-015369-72cjogxz 5767 6 correlation correlation NN cord-015369-72cjogxz 5767 7 with with IN cord-015369-72cjogxz 5767 8 the the DT cord-015369-72cjogxz 5767 9 extent extent NN cord-015369-72cjogxz 5767 10 of of IN cord-015369-72cjogxz 5767 11 pancreatic pancreatic JJ cord-015369-72cjogxz 5767 12 necrosis necrosis NN cord-015369-72cjogxz 5767 13 . . . cord-015369-72cjogxz 5768 1 Increase increase VB cord-015369-72cjogxz 5768 2 in in IN cord-015369-72cjogxz 5768 3 creatinine creatinine NN cord-015369-72cjogxz 5768 4 within within IN cord-015369-72cjogxz 5768 5 the the DT cord-015369-72cjogxz 5768 6 first first JJ cord-015369-72cjogxz 5768 7 48 48 CD cord-015369-72cjogxz 5768 8 h h NN cord-015369-72cjogxz 5768 9 is be VBZ cord-015369-72cjogxz 5768 10 strongly strongly RB cord-015369-72cjogxz 5768 11 associated associate VBN cord-015369-72cjogxz 5768 12 with with IN cord-015369-72cjogxz 5768 13 the the DT cord-015369-72cjogxz 5768 14 development development NN cord-015369-72cjogxz 5768 15 of of IN cord-015369-72cjogxz 5768 16 pancreatic pancreatic JJ cord-015369-72cjogxz 5768 17 necroses necrose NNS cord-015369-72cjogxz 5768 18 . . . cord-015369-72cjogxz 5769 1 Pearson Pearson NNP cord-015369-72cjogxz 5769 2 correlation correlation NN cord-015369-72cjogxz 5769 3 coefficient coefficient NN cord-015369-72cjogxz 5769 4 between between IN cord-015369-72cjogxz 5769 5 the the DT cord-015369-72cjogxz 5769 6 degree degree NN cord-015369-72cjogxz 5769 7 of of IN cord-015369-72cjogxz 5769 8 necrosis necrosis NN cord-015369-72cjogxz 5769 9 and and CC cord-015369-72cjogxz 5769 10 TM TM NNP cord-015369-72cjogxz 5769 11 values value NNS cord-015369-72cjogxz 5769 12 and and CC cord-015369-72cjogxz 5769 13 between between IN cord-015369-72cjogxz 5769 14 the the DT cord-015369-72cjogxz 5769 15 APACHE APACHE NNP cord-015369-72cjogxz 5769 16 II II NNP cord-015369-72cjogxz 5769 17 score score NN cord-015369-72cjogxz 5769 18 and and CC cord-015369-72cjogxz 5769 19 TM TM NNP cord-015369-72cjogxz 5769 20 values value NNS cord-015369-72cjogxz 5769 21 was be VBD cord-015369-72cjogxz 5769 22 statistic statistic NN cord-015369-72cjogxz 5769 23 significant significant JJ cord-015369-72cjogxz 5769 24 . . . cord-015369-72cjogxz 5770 1 Conclusions conclusion NNS cord-015369-72cjogxz 5770 2 . . . cord-015369-72cjogxz 5771 1 The the DT cord-015369-72cjogxz 5771 2 plasma plasma NN cord-015369-72cjogxz 5771 3 TM TM NNP cord-015369-72cjogxz 5771 4 , , , cord-015369-72cjogxz 5771 5 free free JJ cord-015369-72cjogxz 5771 6 DNA DNA NNP cord-015369-72cjogxz 5771 7 may may MD cord-015369-72cjogxz 5771 8 use use VB cord-015369-72cjogxz 5771 9 for for IN cord-015369-72cjogxz 5771 10 identify identify VB cord-015369-72cjogxz 5771 11 pancreatic pancreatic JJ cord-015369-72cjogxz 5771 12 necrosis necrosis NN cord-015369-72cjogxz 5771 13 . . . cord-015369-72cjogxz 5772 1 High high JJ cord-015369-72cjogxz 5772 2 level level NN cord-015369-72cjogxz 5772 3 of of IN cord-015369-72cjogxz 5772 4 creatinine creatinine NN cord-015369-72cjogxz 5772 5 within within IN cord-015369-72cjogxz 5772 6 the the DT cord-015369-72cjogxz 5772 7 first first JJ cord-015369-72cjogxz 5772 8 48 48 CD cord-015369-72cjogxz 5772 9 h h NNP cord-015369-72cjogxz 5772 10 indicates indicate VBZ cord-015369-72cjogxz 5772 11 a a DT cord-015369-72cjogxz 5772 12 high high JJ cord-015369-72cjogxz 5772 13 risk risk NN cord-015369-72cjogxz 5772 14 of of IN cord-015369-72cjogxz 5772 15 pancreatic pancreatic JJ cord-015369-72cjogxz 5772 16 necrosis necrosis NN cord-015369-72cjogxz 5772 17 in in IN cord-015369-72cjogxz 5772 18 patients patient NNS cord-015369-72cjogxz 5772 19 with with IN cord-015369-72cjogxz 5772 20 acute acute JJ cord-015369-72cjogxz 5772 21 pancreatitis pancreatitis NN cord-015369-72cjogxz 5772 22 . . . cord-015369-72cjogxz 5773 1 Need need VB cord-015369-72cjogxz 5773 2 an an DT cord-015369-72cjogxz 5773 3 aggressive aggressive JJ cord-015369-72cjogxz 5773 4 surgical surgical JJ cord-015369-72cjogxz 5773 5 approach approach NN cord-015369-72cjogxz 5773 6 fpr fpr NN cord-015369-72cjogxz 5773 7 management management NN cord-015369-72cjogxz 5773 8 of of IN cord-015369-72cjogxz 5773 9 giant giant JJ cord-015369-72cjogxz 5773 10 cystic cystic JJ cord-015369-72cjogxz 5773 11 pancreas pancreas NN cord-015369-72cjogxz 5773 12 neoplasm neoplasm NN cord-015369-72cjogxz 5773 13 ? ? . cord-015369-72cjogxz 5774 1 Resection resection NN cord-015369-72cjogxz 5774 2 or or CC cord-015369-72cjogxz 5774 3 palliation palliation NN cord-015369-72cjogxz 5774 4 ? ? . cord-015369-72cjogxz 5775 1 S. S. NNP cord-015369-72cjogxz 5775 2 Dubecz Dubecz NNP cord-015369-72cjogxz 5775 3 , , , cord-015369-72cjogxz 5775 4 H. H. NNP cord-015369-72cjogxz 5775 5 Heuberger Heuberger NNP cord-015369-72cjogxz 5775 6 , , , cord-015369-72cjogxz 5775 7 M. M. NNP cord-015369-72cjogxz 5775 8 Prager Prager NNP cord-015369-72cjogxz 5775 9 , , , cord-015369-72cjogxz 5775 10 H. H. NNP cord-015369-72cjogxz 5775 11 Hudler Hudler NNP cord-015369-72cjogxz 5775 12 , , , cord-015369-72cjogxz 5775 13 P. P. NNP cord-015369-72cjogxz 5775 14 Hoffmann Hoffmann NNP cord-015369-72cjogxz 5775 15 , , , cord-015369-72cjogxz 5775 16 K. K. NNP cord-015369-72cjogxz 5775 17 Vetter Vetter NNP cord-015369-72cjogxz 5776 1 The the DT cord-015369-72cjogxz 5776 2 histologically histologically RB cord-015369-72cjogxz 5776 3 unproven unproven JJ cord-015369-72cjogxz 5776 4 giant giant JJ cord-015369-72cjogxz 5776 5 cystic cystic JJ cord-015369-72cjogxz 5776 6 pancreas pancreas NN cord-015369-72cjogxz 5776 7 malignancy malignancy NN cord-015369-72cjogxz 5776 8 is be VBZ cord-015369-72cjogxz 5776 9 a a DT cord-015369-72cjogxz 5776 10 common common JJ cord-015369-72cjogxz 5776 11 problem problem NN cord-015369-72cjogxz 5776 12 for for IN cord-015369-72cjogxz 5776 13 the the DT cord-015369-72cjogxz 5776 14 diagnostic diagnostic JJ cord-015369-72cjogxz 5776 15 team team NN cord-015369-72cjogxz 5776 16 and and CC cord-015369-72cjogxz 5776 17 the the DT cord-015369-72cjogxz 5776 18 surgery surgery NN cord-015369-72cjogxz 5776 19 also also RB cord-015369-72cjogxz 5776 20 . . . cord-015369-72cjogxz 5777 1 His -PRON- PRP$ cord-015369-72cjogxz 5777 2 histological histological JJ cord-015369-72cjogxz 5777 3 confirmation confirmation NN cord-015369-72cjogxz 5777 4 at at IN cord-015369-72cjogxz 5777 5 the the DT cord-015369-72cjogxz 5777 6 asymptomatic asymptomatic JJ cord-015369-72cjogxz 5777 7 neoplasm neoplasm NN cord-015369-72cjogxz 5777 8 are be VBP cord-015369-72cjogxz 5777 9 more more RBR cord-015369-72cjogxz 5777 10 important important JJ cord-015369-72cjogxz 5777 11 the the DT cord-015369-72cjogxz 5777 12 differentiation differentiation NN cord-015369-72cjogxz 5777 13 between between IN cord-015369-72cjogxz 5777 14 of of IN cord-015369-72cjogxz 5777 15 benign benign JJ cord-015369-72cjogxz 5777 16 or or CC cord-015369-72cjogxz 5777 17 malignant malignant JJ cord-015369-72cjogxz 5777 18 desaeses desaese NNS cord-015369-72cjogxz 5777 19 . . . cord-015369-72cjogxz 5778 1 In in IN cord-015369-72cjogxz 5778 2 a a DT cord-015369-72cjogxz 5778 3 rare rare JJ cord-015369-72cjogxz 5778 4 situations situation NNS cord-015369-72cjogxz 5778 5 , , , cord-015369-72cjogxz 5778 6 like like IN cord-015369-72cjogxz 5778 7 the the DT cord-015369-72cjogxz 5778 8 presented present VBN cord-015369-72cjogxz 5778 9 case case NN cord-015369-72cjogxz 5778 10 , , , cord-015369-72cjogxz 5778 11 an an DT cord-015369-72cjogxz 5778 12 extremely extremely RB cord-015369-72cjogxz 5778 13 rare rare JJ cord-015369-72cjogxz 5778 14 malignant malignant JJ cord-015369-72cjogxz 5778 15 tumors tumor NNS cord-015369-72cjogxz 5778 16 ( ( -LRB- cord-015369-72cjogxz 5778 17 acinar acinar JJ cord-015369-72cjogxz 5778 18 cell cell NN cord-015369-72cjogxz 5778 19 carcinoma carcinoma NN cord-015369-72cjogxz 5778 20 ) ) -RRB- cord-015369-72cjogxz 5778 21 can can MD cord-015369-72cjogxz 5778 22 be be VB cord-015369-72cjogxz 5778 23 resected resect VBN cord-015369-72cjogxz 5778 24 without without IN cord-015369-72cjogxz 5778 25 any any DT cord-015369-72cjogxz 5778 26 preoperative preoperative JJ cord-015369-72cjogxz 5778 27 confirmation confirmation NN cord-015369-72cjogxz 5778 28 . . . cord-015369-72cjogxz 5779 1 A a DT cord-015369-72cjogxz 5779 2 73 73 CD cord-015369-72cjogxz 5779 3 year year NN cord-015369-72cjogxz 5779 4 old old JJ cord-015369-72cjogxz 5779 5 man man NN cord-015369-72cjogxz 5779 6 presented present VBN cord-015369-72cjogxz 5779 7 with with IN cord-015369-72cjogxz 5779 8 loss loss NN cord-015369-72cjogxz 5779 9 of of IN cord-015369-72cjogxz 5779 10 appetit appetit NNP cord-015369-72cjogxz 5779 11 , , , cord-015369-72cjogxz 5779 12 history history NN cord-015369-72cjogxz 5779 13 with with IN cord-015369-72cjogxz 5779 14 icterus icterus NN cord-015369-72cjogxz 5779 15 and and CC cord-015369-72cjogxz 5779 16 changes change NNS cord-015369-72cjogxz 5779 17 in in IN cord-015369-72cjogxz 5779 18 bowel bowel NN cord-015369-72cjogxz 5779 19 habits habit NNS cord-015369-72cjogxz 5779 20 and and CC cord-015369-72cjogxz 5779 21 negative negative JJ cord-015369-72cjogxz 5779 22 value value NN cord-015369-72cjogxz 5779 23 with with IN cord-015369-72cjogxz 5779 24 tumour tumour NN cord-015369-72cjogxz 5779 25 markers marker NNS cord-015369-72cjogxz 5779 26 . . . cord-015369-72cjogxz 5780 1 The the DT cord-015369-72cjogxz 5780 2 praeop praeop NN cord-015369-72cjogxz 5780 3 . . . cord-015369-72cjogxz 5781 1 investigations investigation NNS cord-015369-72cjogxz 5781 2 were be VBD cord-015369-72cjogxz 5781 3 the the DT cord-015369-72cjogxz 5781 4 follows follow NNS cord-015369-72cjogxz 5781 5 ( ( -LRB- cord-015369-72cjogxz 5781 6 CT CT NNP cord-015369-72cjogxz 5781 7 : : : cord-015369-72cjogxz 5781 8 8 8 CD cord-015369-72cjogxz 5781 9 cm cm NN cord-015369-72cjogxz 5781 10 large large JJ cord-015369-72cjogxz 5781 11 inhomogen inhomogen NNP cord-015369-72cjogxz 5781 12 pancreashead pancreashead NNP cord-015369-72cjogxz 5781 13 tumour tumour NN cord-015369-72cjogxz 5781 14 , , , cord-015369-72cjogxz 5781 15 with with IN cord-015369-72cjogxz 5781 16 well well RB cord-015369-72cjogxz 5781 17 anhancing anhancing NN cord-015369-72cjogxz 5781 18 wall wall NN cord-015369-72cjogxz 5781 19 , , , cord-015369-72cjogxz 5781 20 without without IN cord-015369-72cjogxz 5781 21 liver liver NN cord-015369-72cjogxz 5781 22 and and CC cord-015369-72cjogxz 5781 23 LN ln NN cord-015369-72cjogxz 5781 24 metastases metastasis NNS cord-015369-72cjogxz 5781 25 , , , cord-015369-72cjogxz 5781 26 ERCP ERCP NNP cord-015369-72cjogxz 5781 27 : : : cord-015369-72cjogxz 5781 28 cysticmucinous cysticmucinous JJ cord-015369-72cjogxz 5781 29 giant giant JJ cord-015369-72cjogxz 5781 30 tumour tumour NN cord-015369-72cjogxz 5781 31 in in IN cord-015369-72cjogxz 5781 32 the the DT cord-015369-72cjogxz 5781 33 papilla papilla NN cord-015369-72cjogxz 5781 34 region region NN cord-015369-72cjogxz 5781 35 , , , cord-015369-72cjogxz 5781 36 with with IN cord-015369-72cjogxz 5781 37 double double JJ cord-015369-72cjogxz 5781 38 duct duct NN cord-015369-72cjogxz 5781 39 occlusion occlusion NN cord-015369-72cjogxz 5781 40 , , , cord-015369-72cjogxz 5781 41 bileduct bileduct NN cord-015369-72cjogxz 5781 42 stanting stanting NN cord-015369-72cjogxz 5781 43 was be VBD cord-015369-72cjogxz 5781 44 not not RB cord-015369-72cjogxz 5781 45 available available JJ cord-015369-72cjogxz 5781 46 , , , cord-015369-72cjogxz 5781 47 Histology histology NN cord-015369-72cjogxz 5781 48 : : : cord-015369-72cjogxz 5781 49 any any DT cord-015369-72cjogxz 5781 50 praeop praeop NN cord-015369-72cjogxz 5781 51 . . . cord-015369-72cjogxz 5782 1 biopsy biopsy NNP cord-015369-72cjogxz 5782 2 was be VBD cord-015369-72cjogxz 5782 3 notmalignant notmalignant NN cord-015369-72cjogxz 5782 4 ) ) -RRB- cord-015369-72cjogxz 5782 5 . . . cord-015369-72cjogxz 5783 1 At at IN cord-015369-72cjogxz 5783 2 the the DT cord-015369-72cjogxz 5783 3 exploration exploration NN cord-015369-72cjogxz 5783 4 we -PRON- PRP cord-015369-72cjogxz 5783 5 found find VBD cord-015369-72cjogxz 5783 6 a a DT cord-015369-72cjogxz 5783 7 large large JJ cord-015369-72cjogxz 5783 8 cystic cystic JJ cord-015369-72cjogxz 5783 9 tumour tumour NN cord-015369-72cjogxz 5783 10 in in IN cord-015369-72cjogxz 5783 11 the the DT cord-015369-72cjogxz 5783 12 pancreashead pancreashead NN cord-015369-72cjogxz 5783 13 without without IN cord-015369-72cjogxz 5783 14 propagation propagation NN cord-015369-72cjogxz 5783 15 to to IN cord-015369-72cjogxz 5783 16 the the DT cord-015369-72cjogxz 5783 17 great great JJ cord-015369-72cjogxz 5783 18 wessels wessels NNPS cord-015369-72cjogxz 5783 19 : : : cord-015369-72cjogxz 5783 20 the the DT cord-015369-72cjogxz 5783 21 frozen frozen JJ cord-015369-72cjogxz 5783 22 histology histology NN cord-015369-72cjogxz 5783 23 was be VBD cord-015369-72cjogxz 5783 24 also also RB cord-015369-72cjogxz 5783 25 negative negative JJ cord-015369-72cjogxz 5783 26 . . . cord-015369-72cjogxz 5784 1 Instead instead RB cord-015369-72cjogxz 5784 2 of of IN cord-015369-72cjogxz 5784 3 originally originally RB cord-015369-72cjogxz 5784 4 planed plane VBN cord-015369-72cjogxz 5784 5 palliation palliation NN cord-015369-72cjogxz 5784 6 we -PRON- PRP cord-015369-72cjogxz 5784 7 performed perform VBD cord-015369-72cjogxz 5784 8 a a DT cord-015369-72cjogxz 5784 9 Whipple Whipple NNP cord-015369-72cjogxz 5784 10 operation operation NN cord-015369-72cjogxz 5784 11 . . . cord-015369-72cjogxz 5785 1 The the DT cord-015369-72cjogxz 5785 2 early early JJ cord-015369-72cjogxz 5785 3 and and CC cord-015369-72cjogxz 5785 4 postoperative postoperative JJ cord-015369-72cjogxz 5785 5 period period NN cord-015369-72cjogxz 5785 6 was be VBD cord-015369-72cjogxz 5785 7 also also RB cord-015369-72cjogxz 5785 8 complicationsfree complicationsfree JJ cord-015369-72cjogxz 5785 9 ( ( -LRB- cord-015369-72cjogxz 5785 10 6 6 CD cord-015369-72cjogxz 5785 11 month month NN cord-015369-72cjogxz 5785 12 follow follow NN cord-015369-72cjogxz 5785 13 - - HYPH cord-015369-72cjogxz 5785 14 up up NN cord-015369-72cjogxz 5785 15 ) ) -RRB- cord-015369-72cjogxz 5785 16 . . . cord-015369-72cjogxz 5786 1 We -PRON- PRP cord-015369-72cjogxz 5786 2 demonstrating demonstrate VBG cord-015369-72cjogxz 5786 3 in in IN cord-015369-72cjogxz 5786 4 details detail NNS cord-015369-72cjogxz 5786 5 the the DT cord-015369-72cjogxz 5786 6 macro- macro- NN cord-015369-72cjogxz 5786 7 , , , cord-015369-72cjogxz 5786 8 and and CC cord-015369-72cjogxz 5786 9 microscopic microscopic JJ cord-015369-72cjogxz 5786 10 path path NN cord-015369-72cjogxz 5786 11 investigations investigation NNS cord-015369-72cjogxz 5786 12 ( ( -LRB- cord-015369-72cjogxz 5786 13 pancreastumor pancreastumor NN cord-015369-72cjogxz 5786 14 with with IN cord-015369-72cjogxz 5786 15 central central JJ cord-015369-72cjogxz 5786 16 haemorrhage haemorrhage NN cord-015369-72cjogxz 5786 17 and and CC cord-015369-72cjogxz 5786 18 necrosis necrosis NN cord-015369-72cjogxz 5786 19 , , , cord-015369-72cjogxz 5786 20 solid solid JJ cord-015369-72cjogxz 5786 21 tubulo tubulo JJ cord-015369-72cjogxz 5786 22 - - HYPH cord-015369-72cjogxz 5786 23 cribriform cribriform NN cord-015369-72cjogxz 5786 24 tissue tissue NN cord-015369-72cjogxz 5786 25 , , , cord-015369-72cjogxz 5786 26 cells cell NNS cord-015369-72cjogxz 5786 27 with with IN cord-015369-72cjogxz 5786 28 hyperchromatic hyperchromatic JJ cord-015369-72cjogxz 5786 29 nuclei nucleus NNS cord-015369-72cjogxz 5786 30 and and CC cord-015369-72cjogxz 5786 31 granular granular JJ cord-015369-72cjogxz 5786 32 , , , cord-015369-72cjogxz 5786 33 with with IN cord-015369-72cjogxz 5786 34 PAS pas NN cord-015369-72cjogxz 5786 35 pos pos NN cord-015369-72cjogxz 5786 36 cytoplasm cytoplasm NN cord-015369-72cjogxz 5786 37 , , , cord-015369-72cjogxz 5786 38 with with IN cord-015369-72cjogxz 5786 39 few few JJ cord-015369-72cjogxz 5786 40 cells cell NNS cord-015369-72cjogxz 5786 41 are be VBP cord-015369-72cjogxz 5786 42 reactive reactive JJ cord-015369-72cjogxz 5786 43 with with IN cord-015369-72cjogxz 5786 44 Chromogranine Chromogranine NNP cord-015369-72cjogxz 5786 45 and and CC cord-015369-72cjogxz 5786 46 Synaptophysine Synaptophysine NNP cord-015369-72cjogxz 5786 47 ) ) -RRB- cord-015369-72cjogxz 5786 48 . . . cord-015369-72cjogxz 5787 1 Also also RB cord-015369-72cjogxz 5787 2 demonstrating demonstrate VBG cord-015369-72cjogxz 5787 3 the the DT cord-015369-72cjogxz 5787 4 literature literature NN cord-015369-72cjogxz 5787 5 of of IN cord-015369-72cjogxz 5787 6 the the DT cord-015369-72cjogxz 5787 7 this this DT cord-015369-72cjogxz 5787 8 very very RB cord-015369-72cjogxz 5787 9 rare rare JJ cord-015369-72cjogxz 5787 10 pancreas pancreas NN cord-015369-72cjogxz 5787 11 malignancy malignancy NN cord-015369-72cjogxz 5787 12 . . . cord-015369-72cjogxz 5788 1 It -PRON- PRP cord-015369-72cjogxz 5788 2 seems seem VBZ cord-015369-72cjogxz 5788 3 to to TO cord-015369-72cjogxz 5788 4 be be VB cord-015369-72cjogxz 5788 5 possible possible JJ cord-015369-72cjogxz 5788 6 to to TO cord-015369-72cjogxz 5788 7 achieve achieve VB cord-015369-72cjogxz 5788 8 a a DT cord-015369-72cjogxz 5788 9 curative curative JJ cord-015369-72cjogxz 5788 10 result result NN cord-015369-72cjogxz 5788 11 with with IN cord-015369-72cjogxz 5788 12 an an DT cord-015369-72cjogxz 5788 13 aggressive aggressive JJ cord-015369-72cjogxz 5788 14 surgical surgical JJ cord-015369-72cjogxz 5788 15 approach approach NN cord-015369-72cjogxz 5788 16 at at IN cord-015369-72cjogxz 5788 17 older old JJR cord-015369-72cjogxz 5788 18 patient patient NN cord-015369-72cjogxz 5788 19 also also RB cord-015369-72cjogxz 5788 20 with with IN cord-015369-72cjogxz 5788 21 a a DT cord-015369-72cjogxz 5788 22 giant giant JJ cord-015369-72cjogxz 5788 23 benign benign JJ cord-015369-72cjogxz 5788 24 or or CC cord-015369-72cjogxz 5788 25 semimalignant semimalignant JJ cord-015369-72cjogxz 5788 26 pancreas pancreas NN cord-015369-72cjogxz 5788 27 neoplasm neoplasm NN cord-015369-72cjogxz 5788 28 . . . cord-015369-72cjogxz 5789 1 Minimally minimally RB cord-015369-72cjogxz 5789 2 invasive invasive JJ cord-015369-72cjogxz 5789 3 methods method NNS cord-015369-72cjogxz 5789 4 and and CC cord-015369-72cjogxz 5789 5 surgery surgery NN cord-015369-72cjogxz 5789 6 at at IN cord-015369-72cjogxz 5789 7 the the DT cord-015369-72cjogxz 5789 8 management management NN cord-015369-72cjogxz 5789 9 of of IN cord-015369-72cjogxz 5789 10 pancreatic pancreatic JJ cord-015369-72cjogxz 5789 11 pseudocyst pseudocyst NN cord-015369-72cjogxz 5789 12 Methods method NNS cord-015369-72cjogxz 5789 13 . . . cord-015369-72cjogxz 5790 1 Two two CD cord-015369-72cjogxz 5790 2 hundred hundred CD cord-015369-72cjogxz 5790 3 and and CC cord-015369-72cjogxz 5790 4 forty forty CD cord-015369-72cjogxz 5790 5 - - HYPH cord-015369-72cjogxz 5790 6 seven seven CD cord-015369-72cjogxz 5790 7 patients patient NNS cord-015369-72cjogxz 5790 8 were be VBD cord-015369-72cjogxz 5790 9 undergo undergo JJ cord-015369-72cjogxz 5790 10 to to TO cord-015369-72cjogxz 5790 11 percutaneous percutaneous JJ cord-015369-72cjogxz 5790 12 puncture puncture NN cord-015369-72cjogxz 5790 13 of of IN cord-015369-72cjogxz 5790 14 PPC ppc NN cord-015369-72cjogxz 5790 15 under under IN cord-015369-72cjogxz 5790 16 ultrasonographic ultrasonographic JJ cord-015369-72cjogxz 5790 17 guidance guidance NN cord-015369-72cjogxz 5790 18 resulted result VBD cord-015369-72cjogxz 5790 19 in in IN cord-015369-72cjogxz 5790 20 drainage drainage NN cord-015369-72cjogxz 5790 21 in in IN cord-015369-72cjogxz 5790 22 63 63 CD cord-015369-72cjogxz 5790 23 patients patient NNS cord-015369-72cjogxz 5790 24 . . . cord-015369-72cjogxz 5791 1 Transpapillary Transpapillary NNP cord-015369-72cjogxz 5791 2 and and CC cord-015369-72cjogxz 5791 3 transmural transmural NNP cord-015369-72cjogxz 5791 4 approaches approach NNS cord-015369-72cjogxz 5791 5 for for IN cord-015369-72cjogxz 5791 6 endoscopic endoscopic JJ cord-015369-72cjogxz 5791 7 internal internal JJ cord-015369-72cjogxz 5791 8 drainage drainage NN cord-015369-72cjogxz 5791 9 were be VBD cord-015369-72cjogxz 5791 10 used use VBN cord-015369-72cjogxz 5791 11 in in IN cord-015369-72cjogxz 5791 12 12 12 CD cord-015369-72cjogxz 5791 13 and and CC cord-015369-72cjogxz 5791 14 62 62 CD cord-015369-72cjogxz 5791 15 patients patient NNS cord-015369-72cjogxz 5791 16 , , , cord-015369-72cjogxz 5791 17 respectively respectively RB cord-015369-72cjogxz 5791 18 . . . cord-015369-72cjogxz 5792 1 Sixty sixty CD cord-015369-72cjogxz 5792 2 - - HYPH cord-015369-72cjogxz 5792 3 eight eight CD cord-015369-72cjogxz 5792 4 patients patient NNS cord-015369-72cjogxz 5792 5 were be VBD cord-015369-72cjogxz 5792 6 undergo undergo JJ cord-015369-72cjogxz 5792 7 to to IN cord-015369-72cjogxz 5792 8 opened open VBN cord-015369-72cjogxz 5792 9 surgery surgery NN cord-015369-72cjogxz 5792 10 : : : cord-015369-72cjogxz 5792 11 internal internal JJ cord-015369-72cjogxz 5792 12 ( ( -LRB- cord-015369-72cjogxz 5792 13 39 39 CD cord-015369-72cjogxz 5792 14 ) ) -RRB- cord-015369-72cjogxz 5792 15 or or CC cord-015369-72cjogxz 5792 16 external external JJ cord-015369-72cjogxz 5792 17 ( ( -LRB- cord-015369-72cjogxz 5792 18 18 18 CD cord-015369-72cjogxz 5792 19 ) ) -RRB- cord-015369-72cjogxz 5792 20 drainage drainage NN cord-015369-72cjogxz 5792 21 of of IN cord-015369-72cjogxz 5792 22 PPC PPC NNP cord-015369-72cjogxz 5792 23 , , , cord-015369-72cjogxz 5792 24 distal distal JJ cord-015369-72cjogxz 5792 25 pancreatectomy pancreatectomy NN cord-015369-72cjogxz 5792 26 with with IN cord-015369-72cjogxz 5792 27 cystectomy cystectomy NN cord-015369-72cjogxz 5792 28 ( ( -LRB- cord-015369-72cjogxz 5792 29 9 9 CD cord-015369-72cjogxz 5792 30 ) ) -RRB- cord-015369-72cjogxz 5792 31 , , , cord-015369-72cjogxz 5792 32 enucleation enucleation NN cord-015369-72cjogxz 5792 33 of of IN cord-015369-72cjogxz 5792 34 the the DT cord-015369-72cjogxz 5792 35 cyst cyst NN cord-015369-72cjogxz 5792 36 ( ( -LRB- cord-015369-72cjogxz 5792 37 2 2 CD cord-015369-72cjogxz 5792 38 ) ) -RRB- cord-015369-72cjogxz 5792 39 . . . cord-015369-72cjogxz 5793 1 Results result NNS cord-015369-72cjogxz 5793 2 . . . cord-015369-72cjogxz 5794 1 PPC PPC NNP cord-015369-72cjogxz 5794 2 have have VBP cord-015369-72cjogxz 5794 3 been be VBN cord-015369-72cjogxz 5794 4 disappeared disappear VBN cord-015369-72cjogxz 5794 5 after after IN cord-015369-72cjogxz 5794 6 percutaneous percutaneous JJ cord-015369-72cjogxz 5794 7 procedures procedure NNS cord-015369-72cjogxz 5794 8 in in IN cord-015369-72cjogxz 5794 9 22.6 22.6 CD cord-015369-72cjogxz 5794 10 % % NN cord-015369-72cjogxz 5794 11 patients patient NNS cord-015369-72cjogxz 5794 12 with with IN cord-015369-72cjogxz 5794 13 mature mature JJ cord-015369-72cjogxz 5794 14 and and CC cord-015369-72cjogxz 5794 15 in in IN cord-015369-72cjogxz 5794 16 68.2 68.2 CD cord-015369-72cjogxz 5794 17 % % NN cord-015369-72cjogxz 5794 18 patients patient NNS cord-015369-72cjogxz 5794 19 with with IN cord-015369-72cjogxz 5794 20 immature immature JJ cord-015369-72cjogxz 5794 21 PPC ppc NN cord-015369-72cjogxz 5794 22 . . . cord-015369-72cjogxz 5795 1 Total total JJ cord-015369-72cjogxz 5795 2 success success NN cord-015369-72cjogxz 5795 3 rate rate NN cord-015369-72cjogxz 5795 4 of of IN cord-015369-72cjogxz 5795 5 endoscopic endoscopic JJ cord-015369-72cjogxz 5795 6 drainage drainage NN cord-015369-72cjogxz 5795 7 of of IN cord-015369-72cjogxz 5795 8 PPC PPC NNP cord-015369-72cjogxz 5795 9 was be VBD cord-015369-72cjogxz 5795 10 93,5 93,5 CD cord-015369-72cjogxz 5795 11 % % NN cord-015369-72cjogxz 5795 12 . . . cord-015369-72cjogxz 5796 1 Four four CD cord-015369-72cjogxz 5796 2 patients patient NNS cord-015369-72cjogxz 5796 3 after after IN cord-015369-72cjogxz 5796 4 surgery surgery NN cord-015369-72cjogxz 5796 5 have have VBP cord-015369-72cjogxz 5796 6 died die VBN cord-015369-72cjogxz 5796 7 ( ( -LRB- cord-015369-72cjogxz 5796 8 6.0 6.0 CD cord-015369-72cjogxz 5796 9 % % NN cord-015369-72cjogxz 5796 10 ) ) -RRB- cord-015369-72cjogxz 5796 11 because because IN cord-015369-72cjogxz 5796 12 of of IN cord-015369-72cjogxz 5796 13 bleeding bleeding NN cord-015369-72cjogxz 5796 14 , , , cord-015369-72cjogxz 5796 15 abscess abscess NN cord-015369-72cjogxz 5796 16 and and CC cord-015369-72cjogxz 5796 17 retroperitoneal retroperitoneal JJ cord-015369-72cjogxz 5796 18 phlegmon phlegmon NN cord-015369-72cjogxz 5796 19 . . . cord-015369-72cjogxz 5797 1 Obtained obtain VBN cord-015369-72cjogxz 5797 2 results result NNS cord-015369-72cjogxz 5797 3 and and CC cord-015369-72cjogxz 5797 4 experience experience NN cord-015369-72cjogxz 5797 5 let let VB cord-015369-72cjogxz 5797 6 us -PRON- PRP cord-015369-72cjogxz 5797 7 to to TO cord-015369-72cjogxz 5797 8 propose propose VB cord-015369-72cjogxz 5797 9 the the DT cord-015369-72cjogxz 5797 10 algorithm algorithm NN cord-015369-72cjogxz 5797 11 for for IN cord-015369-72cjogxz 5797 12 the the DT cord-015369-72cjogxz 5797 13 management management NN cord-015369-72cjogxz 5797 14 of of IN cord-015369-72cjogxz 5797 15 PPC PPC NNP cord-015369-72cjogxz 5797 16 . . . cord-015369-72cjogxz 5798 1 Conclusions conclusion NNS cord-015369-72cjogxz 5798 2 . . . cord-015369-72cjogxz 5799 1 Both both DT cord-015369-72cjogxz 5799 2 percutaneous percutaneous JJ cord-015369-72cjogxz 5799 3 and and CC cord-015369-72cjogxz 5799 4 endoscopic endoscopic JJ cord-015369-72cjogxz 5799 5 methods method NNS cord-015369-72cjogxz 5799 6 are be VBP cord-015369-72cjogxz 5799 7 good good JJ cord-015369-72cjogxz 5799 8 minimally minimally RB cord-015369-72cjogxz 5799 9 invasive invasive JJ cord-015369-72cjogxz 5799 10 alternatives alternative NNS cord-015369-72cjogxz 5799 11 for for IN cord-015369-72cjogxz 5799 12 surgery surgery NN cord-015369-72cjogxz 5799 13 in in IN cord-015369-72cjogxz 5799 14 selected select VBN cord-015369-72cjogxz 5799 15 patients patient NNS cord-015369-72cjogxz 5799 16 , , , cord-015369-72cjogxz 5799 17 but but CC cord-015369-72cjogxz 5799 18 percutaneous percutaneous JJ cord-015369-72cjogxz 5799 19 procedures procedure NNS cord-015369-72cjogxz 5799 20 result result VBP cord-015369-72cjogxz 5799 21 in in IN cord-015369-72cjogxz 5799 22 higher high JJR cord-015369-72cjogxz 5799 23 morbidity morbidity NN cord-015369-72cjogxz 5799 24 and and CC cord-015369-72cjogxz 5799 25 longer long JJR cord-015369-72cjogxz 5799 26 hospital hospital NN cord-015369-72cjogxz 5799 27 stay stay NN cord-015369-72cjogxz 5799 28 . . . cord-015369-72cjogxz 5800 1 The the DT cord-015369-72cjogxz 5800 2 number number NN cord-015369-72cjogxz 5800 3 of of IN cord-015369-72cjogxz 5800 4 successful successful JJ cord-015369-72cjogxz 5800 5 laparoscopic laparoscopic JJ cord-015369-72cjogxz 5800 6 common common JJ cord-015369-72cjogxz 5800 7 bile bile NN cord-015369-72cjogxz 5800 8 duct duct NN cord-015369-72cjogxz 5800 9 exploration exploration NN cord-015369-72cjogxz 5800 10 in in IN cord-015369-72cjogxz 5800 11 patients patient NNS cord-015369-72cjogxz 5800 12 with with IN cord-015369-72cjogxz 5800 13 acute acute JJ cord-015369-72cjogxz 5800 14 cholecystitis cholecystitis NN cord-015369-72cjogxz 5800 15 range range NN cord-015369-72cjogxz 5800 16 from from IN cord-015369-72cjogxz 5800 17 34 34 CD cord-015369-72cjogxz 5800 18 % % NN cord-015369-72cjogxz 5800 19 to to TO cord-015369-72cjogxz 5800 20 98 98 CD cord-015369-72cjogxz 5800 21 % % NN cord-015369-72cjogxz 5800 22 because because IN cord-015369-72cjogxz 5800 23 of of IN cord-015369-72cjogxz 5800 24 changes change NNS cord-015369-72cjogxz 5800 25 of of IN cord-015369-72cjogxz 5800 26 hepatoduodenal hepatoduodenal JJ cord-015369-72cjogxz 5800 27 ligament ligament NN cord-015369-72cjogxz 5800 28 anatomy anatomy NN cord-015369-72cjogxz 5800 29 . . . cord-015369-72cjogxz 5801 1 Background background NN cord-015369-72cjogxz 5801 2 . . . cord-015369-72cjogxz 5802 1 The the DT cord-015369-72cjogxz 5802 2 purpose purpose NN cord-015369-72cjogxz 5802 3 of of IN cord-015369-72cjogxz 5802 4 study study NN cord-015369-72cjogxz 5802 5 was be VBD cord-015369-72cjogxz 5802 6 to to TO cord-015369-72cjogxz 5802 7 prognosticate prognosticate VB cord-015369-72cjogxz 5802 8 possible possible JJ cord-015369-72cjogxz 5802 9 difficulties difficulty NNS cord-015369-72cjogxz 5802 10 and and CC cord-015369-72cjogxz 5802 11 problems problem NNS cord-015369-72cjogxz 5802 12 for for IN cord-015369-72cjogxz 5802 13 laparoscopic laparoscopic JJ cord-015369-72cjogxz 5802 14 choledochoscopy choledochoscopy NN cord-015369-72cjogxz 5802 15 and and CC cord-015369-72cjogxz 5802 16 bile bile NN cord-015369-72cjogxz 5802 17 duct duct NN cord-015369-72cjogxz 5802 18 clearance clearance NN cord-015369-72cjogxz 5802 19 in in IN cord-015369-72cjogxz 5802 20 patients patient NNS cord-015369-72cjogxz 5802 21 with with IN cord-015369-72cjogxz 5802 22 acute acute JJ cord-015369-72cjogxz 5802 23 cholecystitis cholecystitis NN cord-015369-72cjogxz 5802 24 . . . cord-015369-72cjogxz 5803 1 Methods method NNS cord-015369-72cjogxz 5803 2 . . . cord-015369-72cjogxz 5804 1 1460 1460 CD cord-015369-72cjogxz 5804 2 patients patient NNS cord-015369-72cjogxz 5804 3 underwent undergo VBD cord-015369-72cjogxz 5804 4 to to IN cord-015369-72cjogxz 5804 5 laparoscopic laparoscopic JJ cord-015369-72cjogxz 5804 6 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 5804 7 because because IN cord-015369-72cjogxz 5804 8 of of IN cord-015369-72cjogxz 5804 9 acute acute JJ cord-015369-72cjogxz 5804 10 calculous calculous JJ cord-015369-72cjogxz 5804 11 cholecystitis cholecystitis NN cord-015369-72cjogxz 5804 12 . . . cord-015369-72cjogxz 5805 1 By by IN cord-015369-72cjogxz 5805 2 usage usage NN cord-015369-72cjogxz 5805 3 of of IN cord-015369-72cjogxz 5805 4 blood blood NN cord-015369-72cjogxz 5805 5 tests test NNS cord-015369-72cjogxz 5805 6 , , , cord-015369-72cjogxz 5805 7 ultrasonography ultrasonography NN cord-015369-72cjogxz 5805 8 , , , cord-015369-72cjogxz 5805 9 X x NN cord-015369-72cjogxz 5805 10 - - NN cord-015369-72cjogxz 5805 11 ray ray JJ cord-015369-72cjogxz 5805 12 examination examination NN cord-015369-72cjogxz 5805 13 of of IN cord-015369-72cjogxz 5805 14 the the DT cord-015369-72cjogxz 5805 15 gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 5805 16 tract tract NN cord-015369-72cjogxz 5805 17 , , , cord-015369-72cjogxz 5805 18 CT CT NNP cord-015369-72cjogxz 5805 19 , , , cord-015369-72cjogxz 5805 20 MRI MRI NNP cord-015369-72cjogxz 5805 21 , , , cord-015369-72cjogxz 5805 22 endoscopy endoscopy NN cord-015369-72cjogxz 5805 23 in in IN cord-015369-72cjogxz 5805 24 264 264 CD cord-015369-72cjogxz 5805 25 ( ( -LRB- cord-015369-72cjogxz 5805 26 18.1 18.1 CD cord-015369-72cjogxz 5805 27 % % NN cord-015369-72cjogxz 5805 28 ) ) -RRB- cord-015369-72cjogxz 5806 1 patients patient NNS cord-015369-72cjogxz 5806 2 choledocholithiasis choledocholithiasis NNP cord-015369-72cjogxz 5806 3 , , , cord-015369-72cjogxz 5807 1 stenosis stenosis NN cord-015369-72cjogxz 5807 2 of of IN cord-015369-72cjogxz 5807 3 Vater Vater NNP cord-015369-72cjogxz 5807 4 's 's POS cord-015369-72cjogxz 5807 5 papilla papilla NN cord-015369-72cjogxz 5807 6 or or CC cord-015369-72cjogxz 5807 7 peripapillary peripapillary JJ cord-015369-72cjogxz 5807 8 diverticulum diverticulum NN cord-015369-72cjogxz 5807 9 were be VBD cord-015369-72cjogxz 5807 10 revealed reveal VBN cord-015369-72cjogxz 5807 11 and and CC cord-015369-72cjogxz 5807 12 they -PRON- PRP cord-015369-72cjogxz 5807 13 underwent undergo VBD cord-015369-72cjogxz 5807 14 pre pre JJ cord-015369-72cjogxz 5807 15 - - JJ cord-015369-72cjogxz 5807 16 or or CC cord-015369-72cjogxz 5807 17 intraoperative intraoperative JJ cord-015369-72cjogxz 5807 18 common common JJ cord-015369-72cjogxz 5807 19 bile bile NN cord-015369-72cjogxz 5807 20 duct duct NN cord-015369-72cjogxz 5807 21 ( ( -LRB- cord-015369-72cjogxz 5807 22 CBD CBD NNP cord-015369-72cjogxz 5807 23 ) ) -RRB- cord-015369-72cjogxz 5807 24 exploration exploration NN cord-015369-72cjogxz 5807 25 . . . cord-015369-72cjogxz 5808 1 Results result NNS cord-015369-72cjogxz 5808 2 . . . cord-015369-72cjogxz 5809 1 Prognostic prognostic JJ cord-015369-72cjogxz 5809 2 factors factor NNS cord-015369-72cjogxz 5809 3 for for IN cord-015369-72cjogxz 5809 4 difficult difficult JJ cord-015369-72cjogxz 5809 5 and/or and/or CC cord-015369-72cjogxz 5809 6 failed fail VBD cord-015369-72cjogxz 5809 7 laparoscopic laparoscopic JJ cord-015369-72cjogxz 5809 8 CBD CBD NNP cord-015369-72cjogxz 5809 9 exploration exploration NN cord-015369-72cjogxz 5809 10 were be VBD cord-015369-72cjogxz 5809 11 hard hard JJ cord-015369-72cjogxz 5809 12 masses masse NNS cord-015369-72cjogxz 5809 13 in in IN cord-015369-72cjogxz 5809 14 the the DT cord-015369-72cjogxz 5809 15 hepatoduodenal hepatoduodenal JJ cord-015369-72cjogxz 5809 16 ligament ligament NN cord-015369-72cjogxz 5809 17 ( ( -LRB- cord-015369-72cjogxz 5809 18 ultrasonographical ultrasonographical NNP cord-015369-72cjogxz 5809 19 echopositive echopositive NNP cord-015369-72cjogxz 5809 20 paravesicular paravesicular NNP cord-015369-72cjogxz 5809 21 masses masse NNS cord-015369-72cjogxz 5809 22 close close JJ cord-015369-72cjogxz 5809 23 to to IN cord-015369-72cjogxz 5809 24 the the DT cord-015369-72cjogxz 5809 25 gall gall NN cord-015369-72cjogxz 5809 26 bladder bladder NN cord-015369-72cjogxz 5809 27 neck neck NN cord-015369-72cjogxz 5809 28 and/or and/or CC cord-015369-72cjogxz 5809 29 hyperechogenic hyperechogenic JJ cord-015369-72cjogxz 5809 30 strips strip NNS cord-015369-72cjogxz 5809 31 , , , cord-015369-72cjogxz 5809 32 that that IN cord-015369-72cjogxz 5809 33 usually usually RB cord-015369-72cjogxz 5809 34 occurs occur VBZ cord-015369-72cjogxz 5809 35 in in IN cord-015369-72cjogxz 5809 36 7 7 CD cord-015369-72cjogxz 5809 37 - - SYM cord-015369-72cjogxz 5809 38 10 10 CD cord-015369-72cjogxz 5809 39 days day NNS cord-015369-72cjogxz 5809 40 after after IN cord-015369-72cjogxz 5809 41 onset onset NN cord-015369-72cjogxz 5809 42 of of IN cord-015369-72cjogxz 5809 43 acute acute JJ cord-015369-72cjogxz 5809 44 cholecystitis cholecystitis NN cord-015369-72cjogxz 5809 45 ) ) -RRB- cord-015369-72cjogxz 5809 46 , , , cord-015369-72cjogxz 5809 47 paravesical paravesical JJ cord-015369-72cjogxz 5809 48 abscesses abscess NNS cord-015369-72cjogxz 5809 49 , , , cord-015369-72cjogxz 5809 50 thick thick JJ cord-015369-72cjogxz 5809 51 ( ( -LRB- cord-015369-72cjogxz 5809 52 1.5 1.5 CD cord-015369-72cjogxz 5809 53 mm mm NNS cord-015369-72cjogxz 5809 54 and and CC cord-015369-72cjogxz 5809 55 more more JJR cord-015369-72cjogxz 5809 56 ) ) -RRB- cord-015369-72cjogxz 5809 57 wall wall NN cord-015369-72cjogxz 5809 58 of of IN cord-015369-72cjogxz 5809 59 CBD CBD NNP cord-015369-72cjogxz 5809 60 , , , cord-015369-72cjogxz 5809 61 multiple multiple JJ cord-015369-72cjogxz 5809 62 stones stone NNS cord-015369-72cjogxz 5809 63 in in IN cord-015369-72cjogxz 5809 64 the the DT cord-015369-72cjogxz 5809 65 CBD CBD NNP cord-015369-72cjogxz 5809 66 , , , cord-015369-72cjogxz 5809 67 large large JJ cord-015369-72cjogxz 5809 68 stones stone NNS cord-015369-72cjogxz 5809 69 that that WDT cord-015369-72cjogxz 5809 70 completely completely RB cord-015369-72cjogxz 5809 71 filling fill VBG cord-015369-72cjogxz 5809 72 up up RP cord-015369-72cjogxz 5809 73 the the DT cord-015369-72cjogxz 5809 74 CBD CBD NNP cord-015369-72cjogxz 5809 75 , , , cord-015369-72cjogxz 5809 76 peripapillary peripapillary JJ cord-015369-72cjogxz 5809 77 diverticulum diverticulum NN cord-015369-72cjogxz 5809 78 , , , cord-015369-72cjogxz 5809 79 sludge sludge NN cord-015369-72cjogxz 5809 80 with with IN cord-015369-72cjogxz 5809 81 microcholelithiasis microcholelithiasis NN cord-015369-72cjogxz 5809 82 . . . cord-015369-72cjogxz 5810 1 14 14 CD cord-015369-72cjogxz 5810 2 ( ( -LRB- cord-015369-72cjogxz 5810 3 5.3 5.3 CD cord-015369-72cjogxz 5810 4 % % NN cord-015369-72cjogxz 5810 5 ) ) -RRB- cord-015369-72cjogxz 5810 6 patients patient NNS cord-015369-72cjogxz 5810 7 had have VBD cord-015369-72cjogxz 5810 8 conversion conversion NN cord-015369-72cjogxz 5810 9 because because IN cord-015369-72cjogxz 5810 10 of of IN cord-015369-72cjogxz 5810 11 problems problem NNS cord-015369-72cjogxz 5810 12 with with IN cord-015369-72cjogxz 5810 13 CBD CBD NNP cord-015369-72cjogxz 5810 14 exploration exploration NN cord-015369-72cjogxz 5810 15 . . . cord-015369-72cjogxz 5811 1 Conclusions conclusion NNS cord-015369-72cjogxz 5811 2 . . . cord-015369-72cjogxz 5812 1 Laparoscopic laparoscopic JJ cord-015369-72cjogxz 5812 2 cholecystectomy cholecystectomy NN cord-015369-72cjogxz 5812 3 with with IN cord-015369-72cjogxz 5812 4 CBD CBD NNP cord-015369-72cjogxz 5812 5 exploration exploration NN cord-015369-72cjogxz 5812 6 and and CC cord-015369-72cjogxz 5812 7 stone stone NN cord-015369-72cjogxz 5812 8 extraction extraction NN cord-015369-72cjogxz 5812 9 is be VBZ cord-015369-72cjogxz 5812 10 the the DT cord-015369-72cjogxz 5812 11 method method NN cord-015369-72cjogxz 5812 12 of of IN cord-015369-72cjogxz 5812 13 choice choice NN cord-015369-72cjogxz 5812 14 in in IN cord-015369-72cjogxz 5812 15 the the DT cord-015369-72cjogxz 5812 16 treatment treatment NN cord-015369-72cjogxz 5812 17 of of IN cord-015369-72cjogxz 5812 18 patients patient NNS cord-015369-72cjogxz 5812 19 with with IN cord-015369-72cjogxz 5812 20 acute acute JJ cord-015369-72cjogxz 5812 21 cholecystitis cholecystitis NN cord-015369-72cjogxz 5812 22 complicated complicate VBN cord-015369-72cjogxz 5812 23 with with IN cord-015369-72cjogxz 5812 24 choledocholithiasis choledocholithiasis NNP cord-015369-72cjogxz 5812 25 . . . cord-015369-72cjogxz 5813 1 In in IN cord-015369-72cjogxz 5813 2 patients patient NNS cord-015369-72cjogxz 5813 3 with with IN cord-015369-72cjogxz 5813 4 predicted predict VBN cord-015369-72cjogxz 5813 5 difficult difficult JJ cord-015369-72cjogxz 5813 6 laparoscopic laparoscopic JJ cord-015369-72cjogxz 5813 7 CBD CBD NNP cord-015369-72cjogxz 5813 8 exploration exploration NN cord-015369-72cjogxz 5813 9 the the DT cord-015369-72cjogxz 5813 10 preoperative preoperative JJ cord-015369-72cjogxz 5813 11 endoscopic endoscopic JJ cord-015369-72cjogxz 5813 12 retrograde retrograde JJ cord-015369-72cjogxz 5813 13 resolution resolution NN cord-015369-72cjogxz 5813 14 of of IN cord-015369-72cjogxz 5813 15 intracholedocheal intracholedocheal NN cord-015369-72cjogxz 5813 16 problems problem NNS cord-015369-72cjogxz 5813 17 is be VBZ cord-015369-72cjogxz 5813 18 favourable favourable JJ cord-015369-72cjogxz 5813 19 . . . cord-015369-72cjogxz 5814 1 Operative operative JJ cord-015369-72cjogxz 5814 2 treatment treatment NN cord-015369-72cjogxz 5814 3 of of IN cord-015369-72cjogxz 5814 4 pancreatic pancreatic JJ cord-015369-72cjogxz 5814 5 cancer cancer NN cord-015369-72cjogxz 5814 6 : : : cord-015369-72cjogxz 5814 7 our -PRON- PRP$ cord-015369-72cjogxz 5814 8 experience experience NN cord-015369-72cjogxz 5814 9 Y. Y. NNP cord-015369-72cjogxz 5814 10 I. I. NNP cord-015369-72cjogxz 5814 11 Havrysh Havrysh NNP cord-015369-72cjogxz 5814 12 1 1 CD cord-015369-72cjogxz 5814 13 , , , cord-015369-72cjogxz 5814 14 Y. Y. NNP cord-015369-72cjogxz 5814 15 I. i. NN cord-015369-72cjogxz 5814 16 Shavarow Shavarow NNP cord-015369-72cjogxz 5814 17 1 1 CD cord-015369-72cjogxz 5814 18 , , , cord-015369-72cjogxz 5814 19 M. M. NNP cord-015369-72cjogxz 5814 20 P. P. NNP cord-015369-72cjogxz 5814 21 Pavlovskyy Pavlovskyy NNP cord-015369-72cjogxz 5814 22 2 2 CD cord-015369-72cjogxz 5815 1 , , , cord-015369-72cjogxz 5815 2 A. a. NN cord-015369-72cjogxz 5815 3 T. T. NNP cord-015369-72cjogxz 5815 4 Chykaylo Chykaylo NNP cord-015369-72cjogxz 5815 5 1 1 CD cord-015369-72cjogxz 5815 6 1 1 CD cord-015369-72cjogxz 5815 7 Lviv Lviv NNP cord-015369-72cjogxz 5815 8 Regional Regional NNP cord-015369-72cjogxz 5815 9 Hospital Hospital NNP cord-015369-72cjogxz 5815 10 , , , cord-015369-72cjogxz 5815 11 Lviv Lviv NNP cord-015369-72cjogxz 5815 12 , , , cord-015369-72cjogxz 5815 13 Ukraine Ukraine NNP cord-015369-72cjogxz 5815 14 ; ; : cord-015369-72cjogxz 5815 15 2 2 CD cord-015369-72cjogxz 5815 16 Lviv Lviv NNP cord-015369-72cjogxz 5815 17 Medical Medical NNP cord-015369-72cjogxz 5815 18 University University NNP cord-015369-72cjogxz 5815 19 , , , cord-015369-72cjogxz 5815 20 Lviv Lviv NNP cord-015369-72cjogxz 5815 21 , , , cord-015369-72cjogxz 5815 22 Ukraine Ukraine NNP cord-015369-72cjogxz 5816 1 In in IN cord-015369-72cjogxz 5816 2 our -PRON- PRP$ cord-015369-72cjogxz 5816 3 surgical surgical JJ cord-015369-72cjogxz 5816 4 department department NN cord-015369-72cjogxz 5816 5 from from IN cord-015369-72cjogxz 5816 6 1997 1997 CD cord-015369-72cjogxz 5816 7 to to IN cord-015369-72cjogxz 5816 8 2008 2008 CD cord-015369-72cjogxz 5817 1 we -PRON- PRP cord-015369-72cjogxz 5817 2 treatment treatment NN cord-015369-72cjogxz 5817 3 252 252 CD cord-015369-72cjogxz 5817 4 patients patient NNS cord-015369-72cjogxz 5817 5 with with IN cord-015369-72cjogxz 5817 6 cancer cancer NN cord-015369-72cjogxz 5817 7 of of IN cord-015369-72cjogxz 5817 8 pancreas pancrea NNS cord-015369-72cjogxz 5817 9 . . . cord-015369-72cjogxz 5818 1 We -PRON- PRP cord-015369-72cjogxz 5818 2 executed execute VBD cord-015369-72cjogxz 5818 3 : : : cord-015369-72cjogxz 5818 4 52 52 CD cord-015369-72cjogxz 5819 1 Whiplle Whiplle NNP cord-015369-72cjogxz 5819 2 procedure,16 procedure,16 XX cord-015369-72cjogxz 5820 1 left left NNP cord-015369-72cjogxz 5820 2 pancreatectomies pancreatectomy NNS cord-015369-72cjogxz 5820 3 , , , cord-015369-72cjogxz 5820 4 126 126 CD cord-015369-72cjogxz 5820 5 palliative palliative JJ cord-015369-72cjogxz 5820 6 operations operation NNS cord-015369-72cjogxz 5820 7 , , , cord-015369-72cjogxz 5820 8 58 58 CD cord-015369-72cjogxz 5820 9 patients patient NNS cord-015369-72cjogxz 5820 10 were be VBD cord-015369-72cjogxz 5820 11 not not RB cord-015369-72cjogxz 5820 12 operated operate VBN cord-015369-72cjogxz 5820 13 . . . cord-015369-72cjogxz 5821 1 We -PRON- PRP cord-015369-72cjogxz 5821 2 diagnosed diagnose VBD cord-015369-72cjogxz 5821 3 invasion invasion NN cord-015369-72cjogxz 5821 4 of of IN cord-015369-72cjogxz 5821 5 pancreatic pancreatic JJ cord-015369-72cjogxz 5821 6 tumors tumor NNS cord-015369-72cjogxz 5821 7 into into IN cord-015369-72cjogxz 5821 8 Colon colon NN cord-015369-72cjogxz 5821 9 in in IN cord-015369-72cjogxz 5821 10 3 3 CD cord-015369-72cjogxz 5821 11 patients patient NNS cord-015369-72cjogxz 5821 12 , , , cord-015369-72cjogxz 5821 13 into into IN cord-015369-72cjogxz 5821 14 Stomach stomach NN cord-015369-72cjogxz 5821 15 -3 -3 NNP cord-015369-72cjogxz 5821 16 , , , cord-015369-72cjogxz 5821 17 into into IN cord-015369-72cjogxz 5821 18 V. V. NNP cord-015369-72cjogxz 5821 19 Portal Portal NNP cord-015369-72cjogxz 5821 20 -2 -2 NNP cord-015369-72cjogxz 5821 21 , , , cord-015369-72cjogxz 5821 22 into into IN cord-015369-72cjogxz 5821 23 Hepatic hepatic JJ cord-015369-72cjogxz 5821 24 artery artery NN cord-015369-72cjogxz 5821 25 -1 -1 NN cord-015369-72cjogxz 5821 26 . . . cord-015369-72cjogxz 5822 1 From from IN cord-015369-72cjogxz 5822 2 52 52 CD cord-015369-72cjogxz 5822 3 patients patient NNS cord-015369-72cjogxz 5822 4 for for IN cord-015369-72cjogxz 5822 5 which which WDT cord-015369-72cjogxz 5822 6 one one NN cord-015369-72cjogxz 5822 7 was be VBD cord-015369-72cjogxz 5822 8 executed execute VBN cord-015369-72cjogxz 5822 9 Whiplle Whiplle NNP cord-015369-72cjogxz 5822 10 procedure procedure NN cord-015369-72cjogxz 5822 11 : : : cord-015369-72cjogxz 5822 12 male-39 male-39 NNP cord-015369-72cjogxz 5822 13 , , , cord-015369-72cjogxz 5822 14 female-13 female-13 CD cord-015369-72cjogxz 5822 15 . . . cord-015369-72cjogxz 5823 1 Age age NN cord-015369-72cjogxz 5823 2 was be VBD cord-015369-72cjogxz 5823 3 from from IN cord-015369-72cjogxz 5823 4 28 28 CD cord-015369-72cjogxz 5823 5 to to TO cord-015369-72cjogxz 5823 6 74 74 CD cord-015369-72cjogxz 5823 7 years year NNS cord-015369-72cjogxz 5823 8 . . . cord-015369-72cjogxz 5824 1 We -PRON- PRP cord-015369-72cjogxz 5824 2 observed observe VBD cord-015369-72cjogxz 5824 3 mechanical mechanical JJ cord-015369-72cjogxz 5824 4 icterus icterus NN cord-015369-72cjogxz 5824 5 in in IN cord-015369-72cjogxz 5824 6 34 34 CD cord-015369-72cjogxz 5824 7 patients patient NNS cord-015369-72cjogxz 5824 8 . . . cord-015369-72cjogxz 5825 1 We -PRON- PRP cord-015369-72cjogxz 5825 2 used use VBD cord-015369-72cjogxz 5825 3 bilio bilio JJ cord-015369-72cjogxz 5825 4 - - HYPH cord-015369-72cjogxz 5825 5 enteric enteric JJ cord-015369-72cjogxz 5825 6 anastomosis anastomosis NN cord-015369-72cjogxz 5825 7 as as IN cord-015369-72cjogxz 5825 8 first first JJ cord-015369-72cjogxz 5825 9 stage stage NN cord-015369-72cjogxz 5825 10 of of IN cord-015369-72cjogxz 5825 11 the the DT cord-015369-72cjogxz 5825 12 operation operation NN cord-015369-72cjogxz 5825 13 in in IN cord-015369-72cjogxz 5825 14 8 8 CD cord-015369-72cjogxz 5825 15 patients patient NNS cord-015369-72cjogxz 5825 16 and and CC cord-015369-72cjogxz 5825 17 conduction conduction NN cord-015369-72cjogxz 5825 18 of of IN cord-015369-72cjogxz 5825 19 stent stent NN cord-015369-72cjogxz 5825 20 implants implant NNS cord-015369-72cjogxz 5825 21 in in IN cord-015369-72cjogxz 5825 22 16 16 CD cord-015369-72cjogxz 5825 23 patients patient NNS cord-015369-72cjogxz 5825 24 . . . cord-015369-72cjogxz 5826 1 We -PRON- PRP cord-015369-72cjogxz 5826 2 performed perform VBD cord-015369-72cjogxz 5826 3 Pancreatectomy Pancreatectomy NNP cord-015369-72cjogxz 5826 4 Whiplle Whiplle NNP cord-015369-72cjogxz 5826 5 in in IN cord-015369-72cjogxz 5826 6 two two CD cord-015369-72cjogxz 5826 7 stages stage NNS cord-015369-72cjogxz 5826 8 : : : cord-015369-72cjogxz 5826 9 1 1 CD cord-015369-72cjogxz 5826 10 -resectional -resectional JJ cord-015369-72cjogxz 5826 11 stage stage NN cord-015369-72cjogxz 5826 12 , , , cord-015369-72cjogxz 5826 13 2 2 CD cord-015369-72cjogxz 5826 14 -reconstructional -reconstructional JJ cord-015369-72cjogxz 5826 15 stage stage NN cord-015369-72cjogxz 5826 16 . . . cord-015369-72cjogxz 5827 1 Conduct conduct VB cord-015369-72cjogxz 5827 2 a a DT cord-015369-72cjogxz 5827 3 reconstruction reconstruction NN cord-015369-72cjogxz 5827 4 on on IN cord-015369-72cjogxz 5827 5 the the DT cord-015369-72cjogxz 5827 6 isolated isolate VBN cord-015369-72cjogxz 5827 7 loops loop NNS cord-015369-72cjogxz 5827 8 for for IN cord-015369-72cjogxz 5828 1 Roux roux NN cord-015369-72cjogxz 5828 2 - - HYPH cord-015369-72cjogxz 5828 3 en en NN cord-015369-72cjogxz 5828 4 - - HYPH cord-015369-72cjogxz 5828 5 Y. y. NN cord-015369-72cjogxz 5828 6 We -PRON- PRP cord-015369-72cjogxz 5828 7 made make VBD cord-015369-72cjogxz 5828 8 drainage drainage NN cord-015369-72cjogxz 5828 9 outside outside RB cord-015369-72cjogxz 5828 10 of of IN cord-015369-72cjogxz 5828 11 common common JJ cord-015369-72cjogxz 5828 12 bile bile NN cord-015369-72cjogxz 5828 13 duck duck NN cord-015369-72cjogxz 5828 14 and and CC cord-015369-72cjogxz 5828 15 pancreatic pancreatic JJ cord-015369-72cjogxz 5828 16 duck duck NN cord-015369-72cjogxz 5828 17 . . . cord-015369-72cjogxz 5829 1 We -PRON- PRP cord-015369-72cjogxz 5829 2 imposed impose VBD cord-015369-72cjogxz 5829 3 anastomosis anastomosis NN cord-015369-72cjogxz 5829 4 by by IN cord-015369-72cjogxz 5829 5 single single JJ cord-015369-72cjogxz 5829 6 - - HYPH cord-015369-72cjogxz 5829 7 row row NN cord-015369-72cjogxz 5829 8 knotty knotty JJ cord-015369-72cjogxz 5829 9 suture suture NN cord-015369-72cjogxz 5829 10 : : : cord-015369-72cjogxz 5829 11 bilioenteric bilioenteric JJ cord-015369-72cjogxz 5829 12 , , , cord-015369-72cjogxz 5829 13 gastro gastro JJ cord-015369-72cjogxz 5829 14 - - HYPH cord-015369-72cjogxz 5829 15 enteric enteric JJ cord-015369-72cjogxz 5829 16 , , , cord-015369-72cjogxz 5829 17 pancreato pancreato NN cord-015369-72cjogxz 5829 18 - - HYPH cord-015369-72cjogxz 5829 19 enteric enteric JJ cord-015369-72cjogxz 5829 20 , , , cord-015369-72cjogxz 5829 21 entero entero NNP cord-015369-72cjogxz 5829 22 - - HYPH cord-015369-72cjogxz 5829 23 enteric enteric JJ cord-015369-72cjogxz 5829 24 . . . cord-015369-72cjogxz 5830 1 Post post JJ cord-015369-72cjogxz 5830 2 operative operative JJ cord-015369-72cjogxz 5830 3 complications complication NNS cord-015369-72cjogxz 5830 4 : : : cord-015369-72cjogxz 5830 5 bleeding bleed VBG cord-015369-72cjogxz 5830 6 in in IN cord-015369-72cjogxz 5830 7 8 8 CD cord-015369-72cjogxz 5830 8 patients patient NNS cord-015369-72cjogxz 5830 9 , , , cord-015369-72cjogxz 5830 10 acute acute JJ cord-015369-72cjogxz 5830 11 pancreatitis pancreatitis NN cord-015369-72cjogxz 5830 12 in in IN cord-015369-72cjogxz 5830 13 7 7 CD cord-015369-72cjogxz 5830 14 patients patient NNS cord-015369-72cjogxz 5830 15 , , , cord-015369-72cjogxz 5830 16 peritonitis peritonitis NN cord-015369-72cjogxz 5830 17 in in IN cord-015369-72cjogxz 5830 18 6 6 CD cord-015369-72cjogxz 5830 19 patients patient NNS cord-015369-72cjogxz 5830 20 . . . cord-015369-72cjogxz 5831 1 We -PRON- PRP cord-015369-72cjogxz 5831 2 observed observe VBD cord-015369-72cjogxz 5831 3 incapability incapability NN cord-015369-72cjogxz 5831 4 of of IN cord-015369-72cjogxz 5831 5 stitches stitch NNS cord-015369-72cjogxz 5831 6 of of IN cord-015369-72cjogxz 5831 7 pancreato pancreato NN cord-015369-72cjogxz 5831 8 - - HYPH cord-015369-72cjogxz 5831 9 enteric enteric JJ cord-015369-72cjogxz 5831 10 anastomosis anastomosis NN cord-015369-72cjogxz 5831 11 in in IN cord-015369-72cjogxz 5831 12 a a DT cord-015369-72cjogxz 5831 13 4 4 CD cord-015369-72cjogxz 5831 14 patients patient NNS cord-015369-72cjogxz 5831 15 . . . cord-015369-72cjogxz 5832 1 We -PRON- PRP cord-015369-72cjogxz 5832 2 performed perform VBD cord-015369-72cjogxz 5832 3 relaparotomy relaparotomy NN cord-015369-72cjogxz 5832 4 in in IN cord-015369-72cjogxz 5832 5 12 12 CD cord-015369-72cjogxz 5832 6 patients patient NNS cord-015369-72cjogxz 5832 7 . . . cord-015369-72cjogxz 5833 1 Died die VBN cord-015369-72cjogxz 5833 2 -6 -6 JJ cord-015369-72cjogxz 5833 3 patients patient NNS cord-015369-72cjogxz 5833 4 : : : cord-015369-72cjogxz 5833 5 2 2 CD cord-015369-72cjogxz 5833 6 patients patient NNS cord-015369-72cjogxz 5833 7 died die VBD cord-015369-72cjogxz 5833 8 in in IN cord-015369-72cjogxz 5833 9 result result NN cord-015369-72cjogxz 5833 10 of of IN cord-015369-72cjogxz 5833 11 postoperative postoperative JJ cord-015369-72cjogxz 5833 12 bleeding bleeding NN cord-015369-72cjogxz 5833 13 , , , cord-015369-72cjogxz 5833 14 2 2 CD cord-015369-72cjogxz 5833 15 patients patient NNS cord-015369-72cjogxz 5833 16 -from -from JJ cord-015369-72cjogxz 5833 17 acute acute JJ cord-015369-72cjogxz 5833 18 pancreatitis pancreatitis NN cord-015369-72cjogxz 5833 19 , , , cord-015369-72cjogxz 5833 20 2 2 CD cord-015369-72cjogxz 5833 21 patients patient NNS cord-015369-72cjogxz 5833 22 -after -aft JJR cord-015369-72cjogxz 5833 23 peritonitis peritonitis NN cord-015369-72cjogxz 5833 24 . . . cord-015369-72cjogxz 5834 1 Life life NN cord-015369-72cjogxz 5834 2 duration duration NN cord-015369-72cjogxz 5834 3 of of IN cord-015369-72cjogxz 5834 4 our -PRON- PRP$ cord-015369-72cjogxz 5834 5 patients patient NNS cord-015369-72cjogxz 5834 6 after after IN cord-015369-72cjogxz 5834 7 operation operation NN cord-015369-72cjogxz 5834 8 : : : cord-015369-72cjogxz 5834 9 died die VBD cord-015369-72cjogxz 5834 10 till till IN cord-015369-72cjogxz 5834 11 1 1 CD cord-015369-72cjogxz 5834 12 year year NN cord-015369-72cjogxz 5834 13 6 6 CD cord-015369-72cjogxz 5834 14 persons person NNS cord-015369-72cjogxz 5834 15 , , , cord-015369-72cjogxz 5834 16 died die VBD cord-015369-72cjogxz 5834 17 till till IN cord-015369-72cjogxz 5834 18 3 3 CD cord-015369-72cjogxz 5834 19 years year NNS cord-015369-72cjogxz 5834 20 14 14 CD cord-015369-72cjogxz 5834 21 persons person NNS cord-015369-72cjogxz 5834 22 , , , cord-015369-72cjogxz 5834 23 lived live VBD cord-015369-72cjogxz 5834 24 more more JJR cord-015369-72cjogxz 5834 25 than than IN cord-015369-72cjogxz 5834 26 5 5 CD cord-015369-72cjogxz 5834 27 years year NNS cord-015369-72cjogxz 5834 28 8 8 CD cord-015369-72cjogxz 5834 29 persons person NNS cord-015369-72cjogxz 5834 30 , , , cord-015369-72cjogxz 5834 31 lived live VBD cord-015369-72cjogxz 5834 32 more more JJR cord-015369-72cjogxz 5834 33 than than IN cord-015369-72cjogxz 5834 34 10 10 CD cord-015369-72cjogxz 5834 35 years year NNS cord-015369-72cjogxz 5834 36 3 3 CD cord-015369-72cjogxz 5834 37 patients patient NNS cord-015369-72cjogxz 5834 38 . . . cord-015369-72cjogxz 5835 1 Endoscopic endoscopic JJ cord-015369-72cjogxz 5835 2 papillectomy papillectomy NN cord-015369-72cjogxz 5835 3 is be VBZ cord-015369-72cjogxz 5835 4 feasible feasible JJ cord-015369-72cjogxz 5835 5 and and CC cord-015369-72cjogxz 5835 6 safe safe JJ cord-015369-72cjogxz 5835 7 in in IN cord-015369-72cjogxz 5835 8 suspicious suspicious JJ cord-015369-72cjogxz 5835 9 lesions lesion NNS cord-015369-72cjogxz 5835 10 of of IN cord-015369-72cjogxz 5835 11 the the DT cord-015369-72cjogxz 5835 12 papilla papilla NN cord-015369-72cjogxz 5835 13 of of IN cord-015369-72cjogxz 5835 14 Vater Vater NNP cord-015369-72cjogxz 5835 15 ( ( -LRB- cord-015369-72cjogxz 5835 16 case case NN cord-015369-72cjogxz 5835 17 series series NN cord-015369-72cjogxz 5835 18 of of IN cord-015369-72cjogxz 5835 19 54 54 CD cord-015369-72cjogxz 5835 20 patients patient NNS cord-015369-72cjogxz 5835 21 ) ) -RRB- cord-015369-72cjogxz 5836 1 Diabetic diabetic JJ cord-015369-72cjogxz 5836 2 gastroparesis gastroparesis NN cord-015369-72cjogxz 5836 3 ( ( -LRB- cord-015369-72cjogxz 5836 4 DGP DGP NNP cord-015369-72cjogxz 5836 5 ) ) -RRB- cord-015369-72cjogxz 5836 6 represents represent VBZ cord-015369-72cjogxz 5836 7 a a DT cord-015369-72cjogxz 5836 8 chronic chronic JJ cord-015369-72cjogxz 5836 9 gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 5836 10 disorder disorder NN cord-015369-72cjogxz 5836 11 defined define VBN cord-015369-72cjogxz 5836 12 by by IN cord-015369-72cjogxz 5836 13 delayed delay VBN cord-015369-72cjogxz 5836 14 gastric gastric JJ cord-015369-72cjogxz 5836 15 emptying emptying NN cord-015369-72cjogxz 5836 16 in in IN cord-015369-72cjogxz 5836 17 the the DT cord-015369-72cjogxz 5836 18 absence absence NN cord-015369-72cjogxz 5836 19 of of IN cord-015369-72cjogxz 5836 20 mechanical mechanical JJ cord-015369-72cjogxz 5836 21 obstruction obstruction NN cord-015369-72cjogxz 5836 22 . . . cord-015369-72cjogxz 5837 1 Following follow VBG cord-015369-72cjogxz 5837 2 successful successful JJ cord-015369-72cjogxz 5837 3 pancreas pancreas NN cord-015369-72cjogxz 5837 4 transplantation transplantation NN cord-015369-72cjogxz 5837 5 DGP DGP NNP cord-015369-72cjogxz 5837 6 remains remain VBZ cord-015369-72cjogxz 5837 7 a a DT cord-015369-72cjogxz 5837 8 major major JJ cord-015369-72cjogxz 5837 9 concern concern NN cord-015369-72cjogxz 5837 10 in in IN cord-015369-72cjogxz 5837 11 one one CD cord-015369-72cjogxz 5837 12 third third NN cord-015369-72cjogxz 5837 13 of of IN cord-015369-72cjogxz 5837 14 these these DT cord-015369-72cjogxz 5837 15 patients patient NNS cord-015369-72cjogxz 5837 16 . . . cord-015369-72cjogxz 5838 1 Here here RB cord-015369-72cjogxz 5838 2 we -PRON- PRP cord-015369-72cjogxz 5838 3 report report VBP cord-015369-72cjogxz 5838 4 on on IN cord-015369-72cjogxz 5838 5 the the DT cord-015369-72cjogxz 5838 6 application application NN cord-015369-72cjogxz 5838 7 of of IN cord-015369-72cjogxz 5838 8 intrapyloric intrapyloric NNP cord-015369-72cjogxz 5838 9 injection injection NN cord-015369-72cjogxz 5838 10 of of IN cord-015369-72cjogxz 5838 11 botulinum botulinum NN cord-015369-72cjogxz 5838 12 toxin toxin NN cord-015369-72cjogxz 5838 13 A a NN cord-015369-72cjogxz 5838 14 ( ( -LRB- cord-015369-72cjogxz 5838 15 BoTox BoTox NNP cord-015369-72cjogxz 5838 16 ) ) -RRB- cord-015369-72cjogxz 5838 17 in in IN cord-015369-72cjogxz 5838 18 six six CD cord-015369-72cjogxz 5838 19 pancreas pancreas NN cord-015369-72cjogxz 5838 20 recipients recipient NNS cord-015369-72cjogxz 5838 21 . . . cord-015369-72cjogxz 5839 1 All all DT cord-015369-72cjogxz 5839 2 six six CD cord-015369-72cjogxz 5839 3 patients patient NNS cord-015369-72cjogxz 5839 4 ( ( -LRB- cord-015369-72cjogxz 5839 5 four four CD cord-015369-72cjogxz 5839 6 males male NNS cord-015369-72cjogxz 5839 7 ) ) -RRB- cord-015369-72cjogxz 5839 8 with with IN cord-015369-72cjogxz 5839 9 stable stable JJ cord-015369-72cjogxz 5839 10 graft graft NN cord-015369-72cjogxz 5839 11 function function NN cord-015369-72cjogxz 5839 12 suffered suffer VBN cord-015369-72cjogxz 5839 13 from from IN cord-015369-72cjogxz 5839 14 severe severe JJ cord-015369-72cjogxz 5839 15 and and CC cord-015369-72cjogxz 5839 16 persistent persistent JJ cord-015369-72cjogxz 5839 17 gastroparesis gastroparesis NN cord-015369-72cjogxz 5839 18 . . . cord-015369-72cjogxz 5840 1 Symptoms symptom NNS cord-015369-72cjogxz 5840 2 of of IN cord-015369-72cjogxz 5840 3 gastroparesis gastroparesis NN cord-015369-72cjogxz 5840 4 were be VBD cord-015369-72cjogxz 5840 5 quantified quantify VBN cord-015369-72cjogxz 5840 6 by by IN cord-015369-72cjogxz 5840 7 the the DT cord-015369-72cjogxz 5840 8 Patient Patient NNP cord-015369-72cjogxz 5840 9 - - HYPH cord-015369-72cjogxz 5840 10 Assessment Assessment NNP cord-015369-72cjogxz 5840 11 - - HYPH cord-015369-72cjogxz 5840 12 of of IN cord-015369-72cjogxz 5840 13 - - HYPH cord-015369-72cjogxz 5840 14 Gastrointestinal gastrointestinal JJ cord-015369-72cjogxz 5840 15 - - HYPH cord-015369-72cjogxz 5840 16 Symptom symptom NN cord-015369-72cjogxz 5840 17 ( ( -LRB- cord-015369-72cjogxz 5840 18 PAGI PAGI NNP cord-015369-72cjogxz 5840 19 - - HYPH cord-015369-72cjogxz 5840 20 Sym Sym NNP cord-015369-72cjogxz 5840 21 # # $ cord-015369-72cjogxz 5840 22 ) ) -RRB- cord-015369-72cjogxz 5840 23 Severity Severity NNP cord-015369-72cjogxz 5840 24 - - HYPH cord-015369-72cjogxz 5840 25 Index Index NNP cord-015369-72cjogxz 5840 26 before before IN cord-015369-72cjogxz 5840 27 injection injection NN cord-015369-72cjogxz 5840 28 and and CC cord-015369-72cjogxz 5840 29 during during IN cord-015369-72cjogxz 5840 30 follow follow NN cord-015369-72cjogxz 5840 31 - - HYPH cord-015369-72cjogxz 5840 32 up up NN cord-015369-72cjogxz 5840 33 . . . cord-015369-72cjogxz 5841 1 Likewise likewise RB cord-015369-72cjogxz 5841 2 Quality quality NN cord-015369-72cjogxz 5841 3 - - HYPH cord-015369-72cjogxz 5841 4 of of IN cord-015369-72cjogxz 5841 5 - - HYPH cord-015369-72cjogxz 5841 6 Life life NN cord-015369-72cjogxz 5841 7 was be VBD cord-015369-72cjogxz 5841 8 assessed assess VBN cord-015369-72cjogxz 5841 9 ( ( -LRB- cord-015369-72cjogxz 5841 10 PAGI PAGI NNP cord-015369-72cjogxz 5841 11 - - HYPH cord-015369-72cjogxz 5841 12 QoL qol NN cord-015369-72cjogxz 5841 13 # # NN cord-015369-72cjogxz 5841 14 ) ) -RRB- cord-015369-72cjogxz 5841 15 . . . cord-015369-72cjogxz 5842 1 Total total JJ cord-015369-72cjogxz 5842 2 score score NN cord-015369-72cjogxz 5842 3 varies vary VBZ cord-015369-72cjogxz 5842 4 from from IN cord-015369-72cjogxz 5842 5 0 0 CD cord-015369-72cjogxz 5842 6 to to IN cord-015369-72cjogxz 5842 7 5 5 CD cord-015369-72cjogxz 5842 8 . . . cord-015369-72cjogxz 5843 1 To to TO cord-015369-72cjogxz 5843 2 exclude exclude VB cord-015369-72cjogxz 5843 3 other other JJ cord-015369-72cjogxz 5843 4 possible possible JJ cord-015369-72cjogxz 5843 5 underlying underlying JJ cord-015369-72cjogxz 5843 6 causes cause NNS cord-015369-72cjogxz 5843 7 gastric gastric JJ cord-015369-72cjogxz 5843 8 emptying emptying NN cord-015369-72cjogxz 5843 9 was be VBD cord-015369-72cjogxz 5843 10 determined determine VBN cord-015369-72cjogxz 5843 11 by by IN cord-015369-72cjogxz 5843 12 X x NN cord-015369-72cjogxz 5843 13 - - NN cord-015369-72cjogxz 5843 14 ray ray NN cord-015369-72cjogxz 5843 15 and and CC cord-015369-72cjogxz 5843 16 scintigraphic scintigraphic JJ cord-015369-72cjogxz 5843 17 examination examination NN cord-015369-72cjogxz 5843 18 prior prior RB cord-015369-72cjogxz 5843 19 to to IN cord-015369-72cjogxz 5843 20 treatment treatment NN cord-015369-72cjogxz 5843 21 . . . cord-015369-72cjogxz 5844 1 BoToxtherapy BoToxtherapy NNP cord-015369-72cjogxz 5844 2 consisted consist VBD cord-015369-72cjogxz 5844 3 of of IN cord-015369-72cjogxz 5844 4 100U 100u CD cord-015369-72cjogxz 5844 5 injected inject VBN cord-015369-72cjogxz 5844 6 equally equally RB cord-015369-72cjogxz 5844 7 distributed distribute VBN cord-015369-72cjogxz 5844 8 over over IN cord-015369-72cjogxz 5844 9 the the DT cord-015369-72cjogxz 5844 10 four four CD cord-015369-72cjogxz 5844 11 quadrants quadrant NNS cord-015369-72cjogxz 5844 12 of of IN cord-015369-72cjogxz 5844 13 the the DT cord-015369-72cjogxz 5844 14 pylorus pylorus NN cord-015369-72cjogxz 5844 15 . . . cord-015369-72cjogxz 5845 1 Control Control NNP cord-015369-72cjogxz 5845 2 X X NNP cord-015369-72cjogxz 5845 3 - - NN cord-015369-72cjogxz 5845 4 ray ray NNP cord-015369-72cjogxz 5845 5 was be VBD cord-015369-72cjogxz 5845 6 performed perform VBN cord-015369-72cjogxz 5845 7 24 24 CD cord-015369-72cjogxz 5845 8 h h NN cord-015369-72cjogxz 5845 9 later later RB cord-015369-72cjogxz 5845 10 . . . cord-015369-72cjogxz 5846 1 Clear clear JJ cord-015369-72cjogxz 5846 2 effects effect NNS cord-015369-72cjogxz 5846 3 were be VBD cord-015369-72cjogxz 5846 4 evident evident JJ cord-015369-72cjogxz 5846 5 within within IN cord-015369-72cjogxz 5846 6 two two CD cord-015369-72cjogxz 5846 7 weeks week NNS cord-015369-72cjogxz 5846 8 following follow VBG cord-015369-72cjogxz 5846 9 BoTox BoTox NNP cord-015369-72cjogxz 5846 10 - - HYPH cord-015369-72cjogxz 5846 11 injection injection NN cord-015369-72cjogxz 5846 12 in in IN cord-015369-72cjogxz 5846 13 all all DT cord-015369-72cjogxz 5846 14 patients patient NNS cord-015369-72cjogxz 5846 15 . . . cord-015369-72cjogxz 5847 1 While while IN cord-015369-72cjogxz 5847 2 the the DT cord-015369-72cjogxz 5847 3 mean mean JJ cord-015369-72cjogxz 5847 4 symptom symptom NN cord-015369-72cjogxz 5847 5 score score NN cord-015369-72cjogxz 5847 6 before before IN cord-015369-72cjogxz 5847 7 BoTox BoTox NNP cord-015369-72cjogxz 5847 8 - - HYPH cord-015369-72cjogxz 5847 9 application application NN cord-015369-72cjogxz 5847 10 was be VBD cord-015369-72cjogxz 5847 11 3.5 3.5 CD cord-015369-72cjogxz 5847 12 ( ( -LRB- cord-015369-72cjogxz 5847 13 range range VBP cord-015369-72cjogxz 5847 14 2.9 2.9 CD cord-015369-72cjogxz 5847 15 - - SYM cord-015369-72cjogxz 5847 16 4.5 4.5 CD cord-015369-72cjogxz 5847 17 ) ) -RRB- cord-015369-72cjogxz 5847 18 early early RB cord-015369-72cjogxz 5847 19 after after IN cord-015369-72cjogxz 5847 20 treatment treatment NN cord-015369-72cjogxz 5848 1 it -PRON- PRP cord-015369-72cjogxz 5848 2 decreased decrease VBD cord-015369-72cjogxz 5848 3 to to IN cord-015369-72cjogxz 5848 4 0.7 0.7 CD cord-015369-72cjogxz 5848 5 ( ( -LRB- cord-015369-72cjogxz 5848 6 0.3 0.3 CD cord-015369-72cjogxz 5848 7 - - SYM cord-015369-72cjogxz 5848 8 2 2 CD cord-015369-72cjogxz 5848 9 ) ) -RRB- cord-015369-72cjogxz 5848 10 . . . cord-015369-72cjogxz 5849 1 Similarly similarly RB cord-015369-72cjogxz 5849 2 mean mean VB cord-015369-72cjogxz 5850 1 PAGI PAGI NNP cord-015369-72cjogxz 5850 2 - - HYPH cord-015369-72cjogxz 5850 3 QoL#-Index qol#-index NN cord-015369-72cjogxz 5850 4 decreased decrease VBD cord-015369-72cjogxz 5850 5 from from IN cord-015369-72cjogxz 5850 6 2.5 2.5 CD cord-015369-72cjogxz 5850 7 ( ( -LRB- cord-015369-72cjogxz 5850 8 1.6 1.6 CD cord-015369-72cjogxz 5850 9 - - SYM cord-015369-72cjogxz 5850 10 3.2 3.2 CD cord-015369-72cjogxz 5850 11 ) ) -RRB- cord-015369-72cjogxz 5850 12 to to IN cord-015369-72cjogxz 5850 13 1.1 1.1 CD cord-015369-72cjogxz 5850 14 ( ( -LRB- cord-015369-72cjogxz 5850 15 0 0 CD cord-015369-72cjogxz 5850 16 - - SYM cord-015369-72cjogxz 5850 17 2.8 2.8 CD cord-015369-72cjogxz 5850 18 ) ) -RRB- cord-015369-72cjogxz 5850 19 . . . cord-015369-72cjogxz 5851 1 Two two CD cord-015369-72cjogxz 5851 2 patients patient NNS cord-015369-72cjogxz 5851 3 required require VBD cord-015369-72cjogxz 5851 4 a a DT cord-015369-72cjogxz 5851 5 second second JJ cord-015369-72cjogxz 5851 6 injection injection NN cord-015369-72cjogxz 5851 7 due due IN cord-015369-72cjogxz 5851 8 to to IN cord-015369-72cjogxz 5851 9 recurrent recurrent JJ cord-015369-72cjogxz 5851 10 symptoms symptom NNS cord-015369-72cjogxz 5851 11 . . . cord-015369-72cjogxz 5852 1 No no DT cord-015369-72cjogxz 5852 2 adverse adverse JJ cord-015369-72cjogxz 5852 3 events event NNS cord-015369-72cjogxz 5852 4 were be VBD cord-015369-72cjogxz 5852 5 observed observe VBN cord-015369-72cjogxz 5852 6 . . . cord-015369-72cjogxz 5853 1 After after IN cord-015369-72cjogxz 5853 2 a a DT cord-015369-72cjogxz 5853 3 follow follow NN cord-015369-72cjogxz 5853 4 - - HYPH cord-015369-72cjogxz 5853 5 up up NN cord-015369-72cjogxz 5853 6 of of IN cord-015369-72cjogxz 5853 7 457.7 457.7 CD cord-015369-72cjogxz 5853 8 days day NNS cord-015369-72cjogxz 5853 9 ( ( -LRB- cord-015369-72cjogxz 5853 10 65 65 CD cord-015369-72cjogxz 5853 11 - - SYM cord-015369-72cjogxz 5853 12 694 694 CD cord-015369-72cjogxz 5853 13 ) ) -RRB- cord-015369-72cjogxz 5853 14 five five CD cord-015369-72cjogxz 5853 15 of of IN cord-015369-72cjogxz 5853 16 six six CD cord-015369-72cjogxz 5853 17 patients patient NNS cord-015369-72cjogxz 5853 18 experience experience VBP cord-015369-72cjogxz 5853 19 substantial substantial JJ cord-015369-72cjogxz 5853 20 improvements improvement NNS cord-015369-72cjogxz 5853 21 in in IN cord-015369-72cjogxz 5853 22 DGP DGP NNP cord-015369-72cjogxz 5853 23 symptoms symptom NNS cord-015369-72cjogxz 5853 24 and and CC cord-015369-72cjogxz 5853 25 four four CD cord-015369-72cjogxz 5853 26 report report NN cord-015369-72cjogxz 5853 27 considerable considerable JJ cord-015369-72cjogxz 5853 28 amelioration amelioration NN cord-015369-72cjogxz 5853 29 of of IN cord-015369-72cjogxz 5853 30 their -PRON- PRP$ cord-015369-72cjogxz 5853 31 Quality quality NN cord-015369-72cjogxz 5853 32 - - HYPH cord-015369-72cjogxz 5853 33 of of IN cord-015369-72cjogxz 5853 34 - - HYPH cord-015369-72cjogxz 5853 35 Life life NN cord-015369-72cjogxz 5853 36 . . . cord-015369-72cjogxz 5854 1 Intrapyloric Intrapyloric NNP cord-015369-72cjogxz 5854 2 BoTox BoTox NNP cord-015369-72cjogxz 5854 3 - - HYPH cord-015369-72cjogxz 5854 4 injection injection NN cord-015369-72cjogxz 5854 5 should should MD cord-015369-72cjogxz 5854 6 be be VB cord-015369-72cjogxz 5854 7 considered consider VBN cord-015369-72cjogxz 5854 8 in in IN cord-015369-72cjogxz 5854 9 pancreas pancreas NN cord-015369-72cjogxz 5854 10 transplant transplant NN cord-015369-72cjogxz 5854 11 recipients recipient NNS cord-015369-72cjogxz 5854 12 suffering suffer VBG cord-015369-72cjogxz 5854 13 from from IN cord-015369-72cjogxz 5854 14 severe severe JJ cord-015369-72cjogxz 5854 15 DGF dgf NN cord-015369-72cjogxz 5854 16 if if IN cord-015369-72cjogxz 5854 17 they -PRON- PRP cord-015369-72cjogxz 5854 18 are be VBP cord-015369-72cjogxz 5854 19 refractory refractory JJ cord-015369-72cjogxz 5854 20 to to IN cord-015369-72cjogxz 5854 21 prokinetic prokinetic JJ cord-015369-72cjogxz 5854 22 and and CC cord-015369-72cjogxz 5854 23 anti anti JJ cord-015369-72cjogxz 5854 24 - - JJ cord-015369-72cjogxz 5854 25 emetic emetic JJ cord-015369-72cjogxz 5854 26 medication medication NN cord-015369-72cjogxz 5854 27 . . . cord-015369-72cjogxz 5855 1 # # $ cord-015369-72cjogxz 5855 2 2002 2002 CD cord-015369-72cjogxz 5855 3 Johnson&Johnson Johnson&Johnson NNP cord-015369-72cjogxz 5855 4 Pharmaceutical Pharmaceutical NNP cord-015369-72cjogxz 5855 5 Services Services NNP cord-015369-72cjogxz 5855 6 , , , cord-015369-72cjogxz 5855 7 LLC LLC NNP cord-015369-72cjogxz 5855 8 . . . cord-015369-72cjogxz 5856 1 Abscess abscess NN cord-015369-72cjogxz 5856 2 in in IN cord-015369-72cjogxz 5856 3 abdominal abdominal JJ cord-015369-72cjogxz 5856 4 wall wall NN cord-015369-72cjogxz 5856 5 containing contain VBG cord-015369-72cjogxz 5856 6 calculus calculus NN cord-015369-72cjogxz 5856 7 -Cholecystocutaneous -cholecystocutaneous JJ cord-015369-72cjogxz 5856 8 fistula fistula NN cord-015369-72cjogxz 5856 9 secondary secondary JJ cord-015369-72cjogxz 5856 10 to to IN cord-015369-72cjogxz 5856 11 perforation perforation NN cord-015369-72cjogxz 5856 12 of of IN cord-015369-72cjogxz 5856 13 gall gall NN cord-015369-72cjogxz 5856 14 bladder bladder NN cord-015369-72cjogxz 5856 15 : : : cord-015369-72cjogxz 5856 16 a a DT cord-015369-72cjogxz 5856 17 case case NN cord-015369-72cjogxz 5856 18 report report NN cord-015369-72cjogxz 5856 19 Background Background NNP cord-015369-72cjogxz 5856 20 . . . cord-015369-72cjogxz 5857 1 Complications complication NNS cord-015369-72cjogxz 5857 2 of of IN cord-015369-72cjogxz 5857 3 calculus calculus NN cord-015369-72cjogxz 5857 4 cholecystitis cholecystitis NN cord-015369-72cjogxz 5857 5 include include VBP cord-015369-72cjogxz 5857 6 abscess abscess NN cord-015369-72cjogxz 5857 7 up up IN cord-015369-72cjogxz 5857 8 to to IN cord-015369-72cjogxz 5857 9 perforation perforation NN cord-015369-72cjogxz 5857 10 of of IN cord-015369-72cjogxz 5857 11 gallbladder gallbladder NN cord-015369-72cjogxz 5857 12 , , , cord-015369-72cjogxz 5857 13 which which WDT cord-015369-72cjogxz 5857 14 has have VBZ cord-015369-72cjogxz 5857 15 been be VBN cord-015369-72cjogxz 5857 16 classified classify VBN cord-015369-72cjogxz 5857 17 into into IN cord-015369-72cjogxz 5857 18 acute acute JJ cord-015369-72cjogxz 5857 19 ( ( -LRB- cord-015369-72cjogxz 5857 20 free free JJ cord-015369-72cjogxz 5857 21 perforation perforation NN cord-015369-72cjogxz 5857 22 : : : cord-015369-72cjogxz 5857 23 type type NN cord-015369-72cjogxz 5857 24 1 1 CD cord-015369-72cjogxz 5857 25 ) ) -RRB- cord-015369-72cjogxz 5857 26 , , , cord-015369-72cjogxz 5857 27 subacute subacute JJ cord-015369-72cjogxz 5857 28 ( ( -LRB- cord-015369-72cjogxz 5857 29 abscess abscess NN cord-015369-72cjogxz 5857 30 walled wall VBN cord-015369-72cjogxz 5857 31 off off RP cord-015369-72cjogxz 5857 32 by by IN cord-015369-72cjogxz 5857 33 adhesions adhesion NNS cord-015369-72cjogxz 5857 34 : : : cord-015369-72cjogxz 5857 35 type type NN cord-015369-72cjogxz 5857 36 2 2 CD cord-015369-72cjogxz 5857 37 ) ) -RRB- cord-015369-72cjogxz 5857 38 and and CC cord-015369-72cjogxz 5857 39 chronic chronic JJ cord-015369-72cjogxz 5857 40 ( ( -LRB- cord-015369-72cjogxz 5857 41 fistuleous fistuleous JJ cord-015369-72cjogxz 5857 42 communication communication NN cord-015369-72cjogxz 5857 43 in in IN cord-015369-72cjogxz 5857 44 other other JJ cord-015369-72cjogxz 5857 45 viscus viscus NN cord-015369-72cjogxz 5857 46 : : : cord-015369-72cjogxz 5858 1 type type NNP cord-015369-72cjogxz 5858 2 3 3 CD cord-015369-72cjogxz 5858 3 ) ) -RRB- cord-015369-72cjogxz 5858 4 perforation perforation NN cord-015369-72cjogxz 5858 5 refering refer VBG cord-015369-72cjogxz 5858 6 to to IN cord-015369-72cjogxz 5858 7 modified modify VBN cord-015369-72cjogxz 5858 8 Niemeiers Niemeiers NNP cord-015369-72cjogxz 5858 9 classification classification NN cord-015369-72cjogxz 5858 10 . . . cord-015369-72cjogxz 5859 1 Primary primary JJ cord-015369-72cjogxz 5859 2 manifestation manifestation NN cord-015369-72cjogxz 5859 3 of of IN cord-015369-72cjogxz 5859 4 chronic chronic JJ cord-015369-72cjogxz 5859 5 perforated perforated JJ cord-015369-72cjogxz 5859 6 gallbladder gallbladder NN cord-015369-72cjogxz 5859 7 could could MD cord-015369-72cjogxz 5859 8 be be VB cord-015369-72cjogxz 5859 9 presented present VBN cord-015369-72cjogxz 5859 10 as as IN cord-015369-72cjogxz 5859 11 cholecystocutaneous cholecystocutaneous JJ cord-015369-72cjogxz 5859 12 abscess abscess NN cord-015369-72cjogxz 5859 13 / / SYM cord-015369-72cjogxz 5859 14 fistula fistula NN cord-015369-72cjogxz 5859 15 extremely extremely RB cord-015369-72cjogxz 5859 16 infrequent infrequent JJ cord-015369-72cjogxz 5859 17 , , , cord-015369-72cjogxz 5859 18 whereas whereas IN cord-015369-72cjogxz 5859 19 fistula fistula NN cord-015369-72cjogxz 5859 20 in in IN cord-015369-72cjogxz 5859 21 general general JJ cord-015369-72cjogxz 5859 22 occurs occur VBZ cord-015369-72cjogxz 5859 23 in in IN cord-015369-72cjogxz 5859 24 less less JJR cord-015369-72cjogxz 5859 25 than than IN cord-015369-72cjogxz 5859 26 1 1 CD cord-015369-72cjogxz 5859 27 % % NN cord-015369-72cjogxz 5859 28 of of IN cord-015369-72cjogxz 5859 29 patients patient NNS cord-015369-72cjogxz 5859 30 with with IN cord-015369-72cjogxz 5859 31 biliary biliary JJ cord-015369-72cjogxz 5859 32 calculus calculus NN cord-015369-72cjogxz 5859 33 ( ( -LRB- cord-015369-72cjogxz 5859 34 most most RBS cord-015369-72cjogxz 5859 35 likely likely JJ cord-015369-72cjogxz 5859 36 cholecystoduodenal cholecystoduodenal JJ cord-015369-72cjogxz 5859 37 > > XX cord-015369-72cjogxz 5859 38 50 50 CD cord-015369-72cjogxz 5859 39 % % NN cord-015369-72cjogxz 5859 40 ) ) -RRB- cord-015369-72cjogxz 5859 41 . . . cord-015369-72cjogxz 5860 1 Methods method NNS cord-015369-72cjogxz 5860 2 . . . cord-015369-72cjogxz 5861 1 We -PRON- PRP cord-015369-72cjogxz 5861 2 encountered encounter VBD cord-015369-72cjogxz 5861 3 a a DT cord-015369-72cjogxz 5861 4 84 84 CD cord-015369-72cjogxz 5861 5 years year NNS cord-015369-72cjogxz 5861 6 old old JJ cord-015369-72cjogxz 5861 7 patient patient NN cord-015369-72cjogxz 5861 8 presenting present VBG cord-015369-72cjogxz 5861 9 with with IN cord-015369-72cjogxz 5861 10 swelling swell VBG cord-015369-72cjogxz 5861 11 at at IN cord-015369-72cjogxz 5861 12 right right JJ cord-015369-72cjogxz 5861 13 upper upper JJ cord-015369-72cjogxz 5861 14 abdomen abdomen NN cord-015369-72cjogxz 5861 15 with with IN cord-015369-72cjogxz 5861 16 slightly slightly RB cord-015369-72cjogxz 5861 17 elevated elevated JJ cord-015369-72cjogxz 5861 18 WBC WBC NNP cord-015369-72cjogxz 5861 19 and and CC cord-015369-72cjogxz 5861 20 normal normal JJ cord-015369-72cjogxz 5861 21 liver liver NN cord-015369-72cjogxz 5861 22 function function NN cord-015369-72cjogxz 5861 23 test test NN cord-015369-72cjogxz 5861 24 , , , cord-015369-72cjogxz 5861 25 sonography sonography NN cord-015369-72cjogxz 5861 26 and and CC cord-015369-72cjogxz 5861 27 CT CT NNP cord-015369-72cjogxz 5861 28 - - HYPH cord-015369-72cjogxz 5861 29 scan scan NNP cord-015369-72cjogxz 5861 30 confirmed confirm VBD cord-015369-72cjogxz 5861 31 abscess abscess NN cord-015369-72cjogxz 5861 32 and and CC cord-015369-72cjogxz 5861 33 gallbladder gallbladder NN cord-015369-72cjogxz 5861 34 adherent adherent JJ cord-015369-72cjogxz 5861 35 to to IN cord-015369-72cjogxz 5861 36 abdominal abdominal JJ cord-015369-72cjogxz 5861 37 wall wall NN cord-015369-72cjogxz 5861 38 . . . cord-015369-72cjogxz 5862 1 After after IN cord-015369-72cjogxz 5862 2 cutaneous cutaneous JJ cord-015369-72cjogxz 5862 3 drainage drainage NN cord-015369-72cjogxz 5862 4 with with IN cord-015369-72cjogxz 5862 5 spilling spilling NN cord-015369-72cjogxz 5862 6 of of IN cord-015369-72cjogxz 5862 7 calculus calculus NN cord-015369-72cjogxz 5862 8 and and CC cord-015369-72cjogxz 5862 9 conditioning conditioning NN cord-015369-72cjogxz 5862 10 with with IN cord-015369-72cjogxz 5862 11 antibiotics antibiotic NNS cord-015369-72cjogxz 5862 12 preoperatively preoperatively NN cord-015369-72cjogxz 5862 13 secondary secondary JJ cord-015369-72cjogxz 5862 14 laparoscopic laparoscopic NNP cord-015369-72cjogxz 5862 15 cholecystectomie cholecystectomie NNP cord-015369-72cjogxz 5862 16 and and CC cord-015369-72cjogxz 5862 17 fistulectomie fistulectomie NNP cord-015369-72cjogxz 5862 18 were be VBD cord-015369-72cjogxz 5862 19 performed perform VBN cord-015369-72cjogxz 5862 20 . . . cord-015369-72cjogxz 5863 1 Conclusions conclusion NNS cord-015369-72cjogxz 5863 2 . . . cord-015369-72cjogxz 5864 1 In in IN cord-015369-72cjogxz 5864 2 contrary contrary JJ cord-015369-72cjogxz 5864 3 to to IN cord-015369-72cjogxz 5864 4 frequent frequent JJ cord-015369-72cjogxz 5864 5 cholecystocutaneous cholecystocutaneous JJ cord-015369-72cjogxz 5864 6 fistulas fistula NNS cord-015369-72cjogxz 5864 7 in in IN cord-015369-72cjogxz 5864 8 former former JJ cord-015369-72cjogxz 5864 9 times time NNS cord-015369-72cjogxz 5864 10 , , , cord-015369-72cjogxz 5864 11 abscess abscess NN cord-015369-72cjogxz 5864 12 in in IN cord-015369-72cjogxz 5864 13 abdominal abdominal JJ cord-015369-72cjogxz 5864 14 wall wall NN cord-015369-72cjogxz 5864 15 as as IN cord-015369-72cjogxz 5864 16 a a DT cord-015369-72cjogxz 5864 17 result result NN cord-015369-72cjogxz 5864 18 of of IN cord-015369-72cjogxz 5864 19 perforation perforation NN cord-015369-72cjogxz 5864 20 in in IN cord-015369-72cjogxz 5864 21 calculus calculus NN cord-015369-72cjogxz 5864 22 cholecystitis cholecystitis NN cord-015369-72cjogxz 5864 23 is be VBZ cord-015369-72cjogxz 5864 24 a a DT cord-015369-72cjogxz 5864 25 rare rare JJ cord-015369-72cjogxz 5864 26 entity entity NN cord-015369-72cjogxz 5864 27 nowadays nowadays RB cord-015369-72cjogxz 5864 28 due due IN cord-015369-72cjogxz 5864 29 to to IN cord-015369-72cjogxz 5864 30 the the DT cord-015369-72cjogxz 5864 31 advent advent NN cord-015369-72cjogxz 5864 32 of of IN cord-015369-72cjogxz 5864 33 sonography sonography NN cord-015369-72cjogxz 5864 34 , , , cord-015369-72cjogxz 5864 35 antibiotics antibiotic NNS cord-015369-72cjogxz 5864 36 and and CC cord-015369-72cjogxz 5864 37 early early JJ cord-015369-72cjogxz 5864 38 surgical surgical JJ cord-015369-72cjogxz 5864 39 treatment treatment NN cord-015369-72cjogxz 5864 40 of of IN cord-015369-72cjogxz 5864 41 biliary biliary JJ cord-015369-72cjogxz 5864 42 tract tract NN cord-015369-72cjogxz 5864 43 disease disease NN cord-015369-72cjogxz 5864 44 . . . cord-015369-72cjogxz 5865 1 Diagnosis diagnosis NN cord-015369-72cjogxz 5865 2 of of IN cord-015369-72cjogxz 5865 3 cholecystocutaneous cholecystocutaneous JJ cord-015369-72cjogxz 5865 4 abscess abscess NN cord-015369-72cjogxz 5865 5 or or CC cord-015369-72cjogxz 5865 6 fistula fistula NN cord-015369-72cjogxz 5865 7 might may MD cord-015369-72cjogxz 5865 8 be be VB cord-015369-72cjogxz 5865 9 difficult difficult JJ cord-015369-72cjogxz 5865 10 due due IN cord-015369-72cjogxz 5865 11 to to IN cord-015369-72cjogxz 5865 12 the the DT cord-015369-72cjogxz 5865 13 lack lack NN cord-015369-72cjogxz 5865 14 of of IN cord-015369-72cjogxz 5865 15 clinical clinical JJ cord-015369-72cjogxz 5865 16 specifity specifity NN cord-015369-72cjogxz 5865 17 . . . cord-015369-72cjogxz 5866 1 Anyway anyway UH cord-015369-72cjogxz 5866 2 it -PRON- PRP cord-015369-72cjogxz 5866 3 should should MD cord-015369-72cjogxz 5866 4 be be VB cord-015369-72cjogxz 5866 5 considered consider VBN cord-015369-72cjogxz 5866 6 and and CC cord-015369-72cjogxz 5866 7 kept keep VBN cord-015369-72cjogxz 5866 8 in in IN cord-015369-72cjogxz 5866 9 mind mind NN cord-015369-72cjogxz 5866 10 as as IN cord-015369-72cjogxz 5866 11 important important JJ cord-015369-72cjogxz 5866 12 differential differential JJ cord-015369-72cjogxz 5866 13 diagnosis diagnosis NN cord-015369-72cjogxz 5866 14 , , , cord-015369-72cjogxz 5866 15 therefore therefore RB cord-015369-72cjogxz 5866 16 be be VB cord-015369-72cjogxz 5866 17 affirmed affirm VBN cord-015369-72cjogxz 5866 18 aided aid VBN cord-015369-72cjogxz 5866 19 by by IN cord-015369-72cjogxz 5866 20 fistulogram fistulogram NNP cord-015369-72cjogxz 5866 21 , , , cord-015369-72cjogxz 5866 22 accurate accurate JJ cord-015369-72cjogxz 5866 23 ultrasonographic ultrasonographic JJ cord-015369-72cjogxz 5866 24 and and CC cord-015369-72cjogxz 5866 25 CT CT NNP cord-015369-72cjogxz 5866 26 - - HYPH cord-015369-72cjogxz 5866 27 scanfindings scanfinding NNS cord-015369-72cjogxz 5866 28 and and CC cord-015369-72cjogxz 5866 29 clinched clinch VBD cord-015369-72cjogxz 5866 30 with with IN cord-015369-72cjogxz 5866 31 findings finding NNS cord-015369-72cjogxz 5866 32 of of IN cord-015369-72cjogxz 5866 33 bilious bilious JJ cord-015369-72cjogxz 5866 34 fluid fluid NN cord-015369-72cjogxz 5866 35 on on IN cord-015369-72cjogxz 5866 36 drainage drainage NN cord-015369-72cjogxz 5866 37 . . . cord-015369-72cjogxz 5867 1 Increased increase VBN cord-015369-72cjogxz 5867 2 preoperative preoperative JJ cord-015369-72cjogxz 5867 3 awareness awareness NN cord-015369-72cjogxz 5867 4 for for IN cord-015369-72cjogxz 5867 5 diagnosis diagnosis NN cord-015369-72cjogxz 5867 6 of of IN cord-015369-72cjogxz 5867 7 this this DT cord-015369-72cjogxz 5867 8 condition condition NN cord-015369-72cjogxz 5867 9 as as RB cord-015369-72cjogxz 5867 10 well well RB cord-015369-72cjogxz 5867 11 as as IN cord-015369-72cjogxz 5867 12 percutaneous percutaneous JJ cord-015369-72cjogxz 5867 13 drainage drainage NN cord-015369-72cjogxz 5867 14 prior prior RB cord-015369-72cjogxz 5867 15 to to IN cord-015369-72cjogxz 5867 16 subsequent subsequent JJ cord-015369-72cjogxz 5867 17 surgical surgical JJ cord-015369-72cjogxz 5867 18 intervention intervention NN cord-015369-72cjogxz 5867 19 will will MD cord-015369-72cjogxz 5867 20 diminish diminish VB cord-015369-72cjogxz 5867 21 rate rate NN cord-015369-72cjogxz 5867 22 of of IN cord-015369-72cjogxz 5867 23 morbidity morbidity NN cord-015369-72cjogxz 5867 24 and and CC cord-015369-72cjogxz 5867 25 mortality mortality NN cord-015369-72cjogxz 5867 26 of of IN cord-015369-72cjogxz 5867 27 the the DT cord-015369-72cjogxz 5867 28 disease disease NN cord-015369-72cjogxz 5867 29 . . . cord-015369-72cjogxz 5868 1 Background background NN cord-015369-72cjogxz 5868 2 . . . cord-015369-72cjogxz 5869 1 Acute acute JJ cord-015369-72cjogxz 5869 2 sigmoid sigmoid JJ cord-015369-72cjogxz 5869 3 diverticulitis diverticulitis NN cord-015369-72cjogxz 5869 4 is be VBZ cord-015369-72cjogxz 5869 5 a a DT cord-015369-72cjogxz 5869 6 very very RB cord-015369-72cjogxz 5869 7 frequent frequent JJ cord-015369-72cjogxz 5869 8 disease disease NN cord-015369-72cjogxz 5869 9 in in IN cord-015369-72cjogxz 5869 10 western western JJ cord-015369-72cjogxz 5869 11 and and CC cord-015369-72cjogxz 5869 12 industrialized industrialized JJ cord-015369-72cjogxz 5869 13 countries country NNS cord-015369-72cjogxz 5869 14 . . . cord-015369-72cjogxz 5870 1 Immunosuppressed immunosuppressed JJ cord-015369-72cjogxz 5870 2 patients patient NNS cord-015369-72cjogxz 5870 3 show show VBP cord-015369-72cjogxz 5870 4 an an DT cord-015369-72cjogxz 5870 5 increased increase VBN cord-015369-72cjogxz 5870 6 incidence incidence NN cord-015369-72cjogxz 5870 7 of of IN cord-015369-72cjogxz 5870 8 complicated complicated JJ cord-015369-72cjogxz 5870 9 diverticulitis diverticulitis NN cord-015369-72cjogxz 5870 10 and and CC cord-015369-72cjogxz 5870 11 a a DT cord-015369-72cjogxz 5870 12 high high JJ cord-015369-72cjogxz 5870 13 risk risk NN cord-015369-72cjogxz 5870 14 of of IN cord-015369-72cjogxz 5870 15 colonic colonic JJ cord-015369-72cjogxz 5870 16 perforation perforation NN cord-015369-72cjogxz 5870 17 . . . cord-015369-72cjogxz 5871 1 The the DT cord-015369-72cjogxz 5871 2 clinical clinical JJ cord-015369-72cjogxz 5871 3 presentation presentation NN cord-015369-72cjogxz 5871 4 can can MD cord-015369-72cjogxz 5871 5 range range VB cord-015369-72cjogxz 5871 6 from from IN cord-015369-72cjogxz 5871 7 non non JJ cord-015369-72cjogxz 5871 8 - - JJ cord-015369-72cjogxz 5871 9 specific specific JJ cord-015369-72cjogxz 5871 10 signs sign NNS cord-015369-72cjogxz 5871 11 of of IN cord-015369-72cjogxz 5871 12 abdominal abdominal JJ cord-015369-72cjogxz 5871 13 discomfort discomfort NN cord-015369-72cjogxz 5871 14 with with IN cord-015369-72cjogxz 5871 15 delayed delayed JJ cord-015369-72cjogxz 5871 16 diagnosis diagnosis NN cord-015369-72cjogxz 5871 17 of of IN cord-015369-72cjogxz 5871 18 perforation perforation NN cord-015369-72cjogxz 5871 19 to to IN cord-015369-72cjogxz 5871 20 life life NN cord-015369-72cjogxz 5871 21 - - HYPH cord-015369-72cjogxz 5871 22 threatening threaten VBG cord-015369-72cjogxz 5871 23 abdominal abdominal JJ cord-015369-72cjogxz 5871 24 sepsis sepsis NN cord-015369-72cjogxz 5871 25 . . . cord-015369-72cjogxz 5872 1 The the DT cord-015369-72cjogxz 5872 2 standard standard JJ cord-015369-72cjogxz 5872 3 surgical surgical JJ cord-015369-72cjogxz 5872 4 management management NN cord-015369-72cjogxz 5872 5 mainly mainly RB cord-015369-72cjogxz 5872 6 consists consist VBZ cord-015369-72cjogxz 5872 7 of of IN cord-015369-72cjogxz 5872 8 Hartmann Hartmann NNP cord-015369-72cjogxz 5872 9 procedure procedure NN cord-015369-72cjogxz 5872 10 or or CC cord-015369-72cjogxz 5872 11 primary primary JJ cord-015369-72cjogxz 5872 12 anastomosis anastomosis NN cord-015369-72cjogxz 5872 13 , , , cord-015369-72cjogxz 5872 14 but but CC cord-015369-72cjogxz 5872 15 is be VBZ cord-015369-72cjogxz 5872 16 still still RB cord-015369-72cjogxz 5872 17 very very RB cord-015369-72cjogxz 5872 18 controversial controversial JJ cord-015369-72cjogxz 5872 19 due due IN cord-015369-72cjogxz 5872 20 to to IN cord-015369-72cjogxz 5872 21 high high JJ cord-015369-72cjogxz 5872 22 morbidity morbidity NN cord-015369-72cjogxz 5872 23 and and CC cord-015369-72cjogxz 5872 24 mortality mortality NN cord-015369-72cjogxz 5872 25 in in IN cord-015369-72cjogxz 5872 26 both both DT cord-015369-72cjogxz 5872 27 cases case NNS cord-015369-72cjogxz 5872 28 . . . cord-015369-72cjogxz 5873 1 We -PRON- PRP cord-015369-72cjogxz 5873 2 present present VBP cord-015369-72cjogxz 5873 3 four four CD cord-015369-72cjogxz 5873 4 case case NN cord-015369-72cjogxz 5873 5 reports report NNS cord-015369-72cjogxz 5873 6 from from IN cord-015369-72cjogxz 5873 7 our -PRON- PRP$ cord-015369-72cjogxz 5873 8 department department NN cord-015369-72cjogxz 5873 9 with with IN cord-015369-72cjogxz 5873 10 a a DT cord-015369-72cjogxz 5873 11 short short JJ cord-015369-72cjogxz 5873 12 review review NN cord-015369-72cjogxz 5873 13 of of IN cord-015369-72cjogxz 5873 14 literature literature NN cord-015369-72cjogxz 5873 15 . . . cord-015369-72cjogxz 5874 1 Methods method NNS cord-015369-72cjogxz 5874 2 . . . cord-015369-72cjogxz 5875 1 Between between IN cord-015369-72cjogxz 5875 2 2000 2000 CD cord-015369-72cjogxz 5875 3 and and CC cord-015369-72cjogxz 5875 4 2008 2008 CD cord-015369-72cjogxz 5875 5 four four CD cord-015369-72cjogxz 5875 6 patients patient NNS cord-015369-72cjogxz 5875 7 after after IN cord-015369-72cjogxz 5875 8 organ organ NN cord-015369-72cjogxz 5875 9 transplantation transplantation NN cord-015369-72cjogxz 5875 10 ( ( -LRB- cord-015369-72cjogxz 5875 11 lung lung NN cord-015369-72cjogxz 5875 12 Â â CD cord-015369-72cjogxz 5875 13 2 2 CD cord-015369-72cjogxz 5875 14 , , , cord-015369-72cjogxz 5875 15 kidney kidney NN cord-015369-72cjogxz 5875 16 , , , cord-015369-72cjogxz 5875 17 liver liver NN cord-015369-72cjogxz 5875 18 ) ) -RRB- cord-015369-72cjogxz 5875 19 were be VBD cord-015369-72cjogxz 5875 20 admitted admit VBN cord-015369-72cjogxz 5875 21 to to IN cord-015369-72cjogxz 5875 22 the the DT cord-015369-72cjogxz 5875 23 department department NN cord-015369-72cjogxz 5875 24 of of IN cord-015369-72cjogxz 5875 25 surgery surgery NN cord-015369-72cjogxz 5875 26 for for IN cord-015369-72cjogxz 5875 27 acute acute JJ cord-015369-72cjogxz 5875 28 sigmoid sigmoid JJ cord-015369-72cjogxz 5875 29 divertculitis divertculitis NN cord-015369-72cjogxz 5875 30 with with IN cord-015369-72cjogxz 5875 31 free free JJ cord-015369-72cjogxz 5875 32 perforation perforation NN cord-015369-72cjogxz 5875 33 ( ( -LRB- cord-015369-72cjogxz 5875 34 4 4 CD cord-015369-72cjogxz 5875 35 male male JJ cord-015369-72cjogxz 5875 36 patients patient NNS cord-015369-72cjogxz 5875 37 ; ; : cord-015369-72cjogxz 5875 38 median median JJ cord-015369-72cjogxz 5875 39 age age NN cord-015369-72cjogxz 5875 40 65 65 CD cord-015369-72cjogxz 5875 41 , , , cord-015369-72cjogxz 5875 42 range range VBP cord-015369-72cjogxz 5875 43 35 35 CD cord-015369-72cjogxz 5875 44 - - CD cord-015369-72cjogxz 5875 45 87 87 CD cord-015369-72cjogxz 5875 46 ) ) -RRB- cord-015369-72cjogxz 5875 47 . . . cord-015369-72cjogxz 5876 1 Two two CD cord-015369-72cjogxz 5876 2 patients patient NNS cord-015369-72cjogxz 5876 3 underwent undergo VBD cord-015369-72cjogxz 5876 4 a a DT cord-015369-72cjogxz 5876 5 Hartmann Hartmann NNP cord-015369-72cjogxz 5876 6 procedure procedure NN cord-015369-72cjogxz 5876 7 , , , cord-015369-72cjogxz 5876 8 two two CD cord-015369-72cjogxz 5876 9 patients patient NNS cord-015369-72cjogxz 5876 10 had have VBD cord-015369-72cjogxz 5876 11 a a DT cord-015369-72cjogxz 5876 12 primary primary JJ cord-015369-72cjogxz 5876 13 anastomosis anastomosis NN cord-015369-72cjogxz 5876 14 . . . cord-015369-72cjogxz 5877 1 Results result NNS cord-015369-72cjogxz 5877 2 . . . cord-015369-72cjogxz 5878 1 The the DT cord-015369-72cjogxz 5878 2 time time NN cord-015369-72cjogxz 5878 3 interval interval NN cord-015369-72cjogxz 5878 4 between between IN cord-015369-72cjogxz 5878 5 transplantation transplantation NN cord-015369-72cjogxz 5878 6 and and CC cord-015369-72cjogxz 5878 7 perforation perforation NN cord-015369-72cjogxz 5878 8 ranged range VBN cord-015369-72cjogxz 5878 9 between between IN cord-015369-72cjogxz 5878 10 7 7 CD cord-015369-72cjogxz 5878 11 months month NNS cord-015369-72cjogxz 5878 12 and and CC cord-015369-72cjogxz 5878 13 12 12 CD cord-015369-72cjogxz 5878 14 years year NNS cord-015369-72cjogxz 5878 15 with with IN cord-015369-72cjogxz 5878 16 two two CD cord-015369-72cjogxz 5878 17 patients patient NNS cord-015369-72cjogxz 5878 18 having have VBG cord-015369-72cjogxz 5878 19 a a DT cord-015369-72cjogxz 5878 20 history history NN cord-015369-72cjogxz 5878 21 of of IN cord-015369-72cjogxz 5878 22 diverticulitis diverticulitis NN cord-015369-72cjogxz 5878 23 . . . cord-015369-72cjogxz 5879 1 A a DT cord-015369-72cjogxz 5879 2 dehiscence dehiscence NN cord-015369-72cjogxz 5879 3 after after IN cord-015369-72cjogxz 5879 4 laparotomy laparotomy NN cord-015369-72cjogxz 5879 5 and and CC cord-015369-72cjogxz 5879 6 an an DT cord-015369-72cjogxz 5879 7 anastomotic anastomotic JJ cord-015369-72cjogxz 5879 8 leakage leakage NN cord-015369-72cjogxz 5879 9 required require VBN cord-015369-72cjogxz 5879 10 revisional revisional JJ cord-015369-72cjogxz 5879 11 surgery surgery NN cord-015369-72cjogxz 5879 12 in in IN cord-015369-72cjogxz 5879 13 two two CD cord-015369-72cjogxz 5879 14 patients patient NNS cord-015369-72cjogxz 5879 15 . . . cord-015369-72cjogxz 5880 1 Postoperative postoperative JJ cord-015369-72cjogxz 5880 2 morbidity morbidity NN cord-015369-72cjogxz 5880 3 included include VBD cord-015369-72cjogxz 5880 4 acute acute JJ cord-015369-72cjogxz 5880 5 rejection rejection NN cord-015369-72cjogxz 5880 6 , , , cord-015369-72cjogxz 5880 7 pneumonia pneumonia NN cord-015369-72cjogxz 5880 8 and and CC cord-015369-72cjogxz 5880 9 acute acute JJ cord-015369-72cjogxz 5880 10 renal renal JJ cord-015369-72cjogxz 5880 11 failure failure NN cord-015369-72cjogxz 5880 12 . . . cord-015369-72cjogxz 5881 1 Two two CD cord-015369-72cjogxz 5881 2 patients patient NNS cord-015369-72cjogxz 5881 3 died die VBD cord-015369-72cjogxz 5881 4 with with IN cord-015369-72cjogxz 5881 5 MODS mods NN cord-015369-72cjogxz 5881 6 following follow VBG cord-015369-72cjogxz 5881 7 pneumonia pneumonia NN cord-015369-72cjogxz 5881 8 and and CC cord-015369-72cjogxz 5881 9 acute acute JJ cord-015369-72cjogxz 5881 10 rejection rejection NN cord-015369-72cjogxz 5881 11 ( ( -LRB- cord-015369-72cjogxz 5881 12 bilateral bilateral JJ cord-015369-72cjogxz 5881 13 lung lung NN cord-015369-72cjogxz 5881 14 transplantation transplantation NN cord-015369-72cjogxz 5881 15 ) ) -RRB- cord-015369-72cjogxz 5881 16 . . . cord-015369-72cjogxz 5882 1 Conclusions conclusion NNS cord-015369-72cjogxz 5882 2 . . . cord-015369-72cjogxz 5883 1 Sigmoid sigmoid JJ cord-015369-72cjogxz 5883 2 perforation perforation NN cord-015369-72cjogxz 5883 3 in in IN cord-015369-72cjogxz 5883 4 transplant transplant NN cord-015369-72cjogxz 5883 5 recipients recipient NNS cord-015369-72cjogxz 5883 6 is be VBZ cord-015369-72cjogxz 5883 7 a a DT cord-015369-72cjogxz 5883 8 rare rare JJ cord-015369-72cjogxz 5883 9 , , , cord-015369-72cjogxz 5883 10 but but CC cord-015369-72cjogxz 5883 11 life life NN cord-015369-72cjogxz 5883 12 - - HYPH cord-015369-72cjogxz 5883 13 threatening threaten VBG cord-015369-72cjogxz 5883 14 event event NN cord-015369-72cjogxz 5883 15 with with IN cord-015369-72cjogxz 5883 16 a a DT cord-015369-72cjogxz 5883 17 high high JJ cord-015369-72cjogxz 5883 18 mortality mortality NN cord-015369-72cjogxz 5883 19 . . . cord-015369-72cjogxz 5884 1 Elective elective JJ cord-015369-72cjogxz 5884 2 surgical surgical JJ cord-015369-72cjogxz 5884 3 interventions intervention NNS cord-015369-72cjogxz 5884 4 should should MD cord-015369-72cjogxz 5884 5 be be VB cord-015369-72cjogxz 5884 6 considered consider VBN cord-015369-72cjogxz 5884 7 in in IN cord-015369-72cjogxz 5884 8 patients patient NNS cord-015369-72cjogxz 5884 9 with with IN cord-015369-72cjogxz 5884 10 high high JJ cord-015369-72cjogxz 5884 11 risk risk NN cord-015369-72cjogxz 5884 12 of of IN cord-015369-72cjogxz 5884 13 perforation perforation NN cord-015369-72cjogxz 5884 14 ( ( -LRB- cord-015369-72cjogxz 5884 15 history history NN cord-015369-72cjogxz 5884 16 of of IN cord-015369-72cjogxz 5884 17 diverticulitis diverticulitis NN cord-015369-72cjogxz 5884 18 , , , cord-015369-72cjogxz 5884 19 steroid steroid NN cord-015369-72cjogxz 5884 20 immunosuppression immunosuppression NN cord-015369-72cjogxz 5884 21 and and CC cord-015369-72cjogxz 5884 22 heart heart NN cord-015369-72cjogxz 5884 23 / / SYM cord-015369-72cjogxz 5884 24 lung lung NN cord-015369-72cjogxz 5884 25 transplantation transplantation NN cord-015369-72cjogxz 5884 26 ) ) -RRB- cord-015369-72cjogxz 5884 27 . . . cord-015369-72cjogxz 5885 1 Außergewöhnlicher Außergewöhnlicher NNP cord-015369-72cjogxz 5885 2 Kasus Kasus NNP cord-015369-72cjogxz 5885 3 der der NNP cord-015369-72cjogxz 5885 4 Ausbildung Ausbildung NNP cord-015369-72cjogxz 5885 5 von von NNP cord-015369-72cjogxz 5885 6 kolorektalen kolorektalen NNP cord-015369-72cjogxz 5885 7 Karzinomen Karzinomen NNP cord-015369-72cjogxz 5885 8 an an DT cord-015369-72cjogxz 5885 9 4 4 CD cord-015369-72cjogxz 5885 10 Lokalisationen Lokalisationen NNP cord-015369-72cjogxz 5885 11 bei bei NNP cord-015369-72cjogxz 5885 12 Pancolitis Pancolitis NNP cord-015369-72cjogxz 5885 13 ulcerosa ulcerosa NNP cord-015369-72cjogxz 5885 14 eines eines NNP cord-015369-72cjogxz 5886 1 jungen jungen NNP cord-015369-72cjogxz 5886 2 Patienten Patienten NNP cord-015369-72cjogxz 5886 3 Es Es NNP cord-015369-72cjogxz 5887 1 ist ist NNP cord-015369-72cjogxz 5887 2 hinreichend hinreichend NNP cord-015369-72cjogxz 5887 3 bekannt bekannt NNP cord-015369-72cjogxz 5887 4 , , , cord-015369-72cjogxz 5887 5 dass dass NNP cord-015369-72cjogxz 5887 6 die die VBP cord-015369-72cjogxz 5887 7 Colitis Colitis NNP cord-015369-72cjogxz 5887 8 ulcerosa ulcerosa NN cord-015369-72cjogxz 5888 1 als als NNP cord-015369-72cjogxz 5888 2 Präkanzerose Präkanzerose NNP cord-015369-72cjogxz 5889 1 für für NNP cord-015369-72cjogxz 5889 2 die die VBP cord-015369-72cjogxz 5889 3 Generation Generation NNP cord-015369-72cjogxz 5889 4 eines eines NNP cord-015369-72cjogxz 5889 5 Colonkarzinoms Colonkarzinoms NNP cord-015369-72cjogxz 5889 6 gilt gilt NN cord-015369-72cjogxz 5889 7 . . . cord-015369-72cjogxz 5890 1 Bei Bei NNP cord-015369-72cjogxz 5890 2 einem einem NNP cord-015369-72cjogxz 5891 1 36-jährigen 36-jährigen CD cord-015369-72cjogxz 5891 2 Patienten Patienten NNP cord-015369-72cjogxz 5891 3 wurde wurde NNP cord-015369-72cjogxz 5892 1 i -PRON- PRP cord-015369-72cjogxz 5892 2 m be VBP cord-015369-72cjogxz 5892 3 Rahmen Rahmen NNP cord-015369-72cjogxz 5892 4 einer einer NNP cord-015369-72cjogxz 5892 5 Koloskopie Koloskopie NNP cord-015369-72cjogxz 5892 6 wegen wegen NNP cord-015369-72cjogxz 5892 7 persistierender persistierender NNP cord-015369-72cjogxz 5892 8 Abdominalbeschwerden Abdominalbeschwerden NNP cord-015369-72cjogxz 5892 9 eine eine NNP cord-015369-72cjogxz 5892 10 Pancolitis Pancolitis NNP cord-015369-72cjogxz 5892 11 ulcerosa ulcerosa NNP cord-015369-72cjogxz 5892 12 diagnostiziert diagnostiziert NNP cord-015369-72cjogxz 5892 13 , , , cord-015369-72cjogxz 5892 14 die die VB cord-015369-72cjogxz 5892 15 außerdem außerdem NNP cord-015369-72cjogxz 5892 16 intraepitheliale intraepitheliale NNP cord-015369-72cjogxz 5892 17 Neoplasien Neoplasien NNP cord-015369-72cjogxz 5892 18 nachwies nachwie NNS cord-015369-72cjogxz 5892 19 . . . cord-015369-72cjogxz 5893 1 Erkrankungsassoziierte Erkrankungsassoziierte NNP cord-015369-72cjogxz 5893 2 Incompliance Incompliance NNP cord-015369-72cjogxz 5893 3 mit mit NNP cord-015369-72cjogxz 5893 4 temporärer temporärer NN cord-015369-72cjogxz 5893 5 Therapieablehnung Therapieablehnung NNP cord-015369-72cjogxz 5893 6 für für IN cord-015369-72cjogxz 5893 7 1 1 CD cord-015369-72cjogxz 5893 8 Jahr Jahr NNP cord-015369-72cjogxz 5893 9 führte führte NN cord-015369-72cjogxz 5894 1 zu zu NNP cord-015369-72cjogxz 5894 2 einer einer NNP cord-015369-72cjogxz 5894 3 beträchtlichen beträchtlichen NNP cord-015369-72cjogxz 5894 4 Verzögerung Verzögerung NNP cord-015369-72cjogxz 5894 5 der der NNP cord-015369-72cjogxz 5894 6 indizierten indizierten NNP cord-015369-72cjogxz 5894 7 Proktokolektomie Proktokolektomie NNP cord-015369-72cjogxz 5894 8 , , , cord-015369-72cjogxz 5894 9 die die VB cord-015369-72cjogxz 5894 10 letztlich letztlich NNP cord-015369-72cjogxz 5894 11 ein ein NNP cord-015369-72cjogxz 5894 12 inzidentelles inzidentelles NNPS cord-015369-72cjogxz 5894 13 , , , cord-015369-72cjogxz 5894 14 simultanes simultanes NNP cord-015369-72cjogxz 5894 15 kolorektales kolorektales NNP cord-015369-72cjogxz 5894 16 Karzinom Karzinom NNP cord-015369-72cjogxz 5895 1 an an DT cord-015369-72cjogxz 5895 2 4 4 CD cord-015369-72cjogxz 5895 3 Lokalisationen Lokalisationen NNP cord-015369-72cjogxz 5895 4 ergab ergab NNP cord-015369-72cjogxz 5895 5 [ [ -LRB- cord-015369-72cjogxz 5895 6 4 4 CD cord-015369-72cjogxz 5895 7 Â â NN cord-015369-72cjogxz 5895 8 pT3c pt3c CD cord-015369-72cjogxz 5895 9 pN1 pn1 NN cord-015369-72cjogxz 5895 10 ( ( -LRB- cord-015369-72cjogxz 5895 11 2/104 2/104 CD cord-015369-72cjogxz 5895 12 ) ) -RRB- cord-015369-72cjogxz 5895 13 M0 m0 NN cord-015369-72cjogxz 5895 14 ] ] -RRB- cord-015369-72cjogxz 5895 15 . . . cord-015369-72cjogxz 5896 1 Eine Eine NNP cord-015369-72cjogxz 5896 2 adjuvante adjuvante JJ cord-015369-72cjogxz 5896 3 Radiochemotherapie Radiochemotherapie NNP cord-015369-72cjogxz 5896 4 konnte konnte NNP cord-015369-72cjogxz 5896 5 aufgrund aufgrund NNP cord-015369-72cjogxz 5896 6 von von NNP cord-015369-72cjogxz 5896 7 Wundheilungsstörungen Wundheilungsstörungen NNP cord-015369-72cjogxz 5896 8 und und IN cord-015369-72cjogxz 5896 9 Nebenwirkungen Nebenwirkungen NNP cord-015369-72cjogxz 5896 10 nur nur NNP cord-015369-72cjogxz 5896 11 verzögert verzögert NNP cord-015369-72cjogxz 5897 1 und und NNP cord-015369-72cjogxz 5897 2 nicht nicht NNP cord-015369-72cjogxz 5897 3 zeitgerecht zeitgerecht NNP cord-015369-72cjogxz 5897 4 durchgeführt durchgeführt NNP cord-015369-72cjogxz 5898 1 werden werden NNP cord-015369-72cjogxz 5898 2 . . . cord-015369-72cjogxz 5899 1 Der Der NNP cord-015369-72cjogxz 5899 2 Patient Patient NNP cord-015369-72cjogxz 5899 3 war war NN cord-015369-72cjogxz 5899 4 9 9 CD cord-015369-72cjogxz 5899 5 Monate Monate NNP cord-015369-72cjogxz 5899 6 postoperativ postoperativ JJ cord-015369-72cjogxz 5899 7 rezidivfrei rezidivfrei NNS cord-015369-72cjogxz 5899 8 , , , cord-015369-72cjogxz 5899 9 erlag erlag NNP cord-015369-72cjogxz 5899 10 jedoch jedoch NNP cord-015369-72cjogxz 5900 1 i -PRON- PRP cord-015369-72cjogxz 5900 2 m be VBP cord-015369-72cjogxz 5900 3 Verlauf Verlauf NNP cord-015369-72cjogxz 5900 4 nach nach NN cord-015369-72cjogxz 5900 5 einer einer NNP cord-015369-72cjogxz 5900 6 Notoperation Notoperation NNP cord-015369-72cjogxz 5900 7 bei bei NNP cord-015369-72cjogxz 5900 8 Bridenileus Bridenileus NNP cord-015369-72cjogxz 5900 9 einer einer JJ cord-015369-72cjogxz 5900 10 Sepsis sepsis NN cord-015369-72cjogxz 5900 11 . . . cord-015369-72cjogxz 5901 1 Trotz Trotz NNP cord-015369-72cjogxz 5901 2 bekannter bekannter NN cord-015369-72cjogxz 5901 3 Prädisposition Prädisposition NNP cord-015369-72cjogxz 5901 4 bei bei NNP cord-015369-72cjogxz 5901 5 Colitis colitis NN cord-015369-72cjogxz 5902 1 ulcerosa ulcerosa NNP cord-015369-72cjogxz 5902 2 ist ist NNP cord-015369-72cjogxz 5902 3 die die VB cord-015369-72cjogxz 5903 1 Ausbildung Ausbildung NNP cord-015369-72cjogxz 5903 2 eines eine NNS cord-015369-72cjogxz 5904 1 kolorektalen kolorektalen NNP cord-015369-72cjogxz 5904 2 Karzinoms Karzinoms NNP cord-015369-72cjogxz 5905 1 noch noch NNP cord-015369-72cjogxz 5905 2 immer immer NNP cord-015369-72cjogxz 5906 1 ein ein NNP cord-015369-72cjogxz 5906 2 relevantes relevantes NNP cord-015369-72cjogxz 5906 3 pathogenetisches pathogenetisches NNP cord-015369-72cjogxz 5907 1 Geschehen geschehen NN cord-015369-72cjogxz 5907 2 i -PRON- PRP cord-015369-72cjogxz 5907 3 m be VBP cord-015369-72cjogxz 5907 4 Krankheitsverlauf Krankheitsverlauf NNP cord-015369-72cjogxz 5907 5 . . . cord-015369-72cjogxz 5908 1 Insbesondere Insbesondere NNP cord-015369-72cjogxz 5908 2 können können NNP cord-015369-72cjogxz 5908 3 Diagnoseverzögerung Diagnoseverzögerung NNP cord-015369-72cjogxz 5908 4 und und IN cord-015369-72cjogxz 5908 5 Incompliance Incompliance NNP cord-015369-72cjogxz 5908 6 das das NNP cord-015369-72cjogxz 5908 7 Risiko Risiko NNP cord-015369-72cjogxz 5908 8 der der NNP cord-015369-72cjogxz 5908 9 Manifestation Manifestation NNP cord-015369-72cjogxz 5908 10 maligner maligner NN cord-015369-72cjogxz 5908 11 Läsionen Läsionen NNP cord-015369-72cjogxz 5908 12 , , , cord-015369-72cjogxz 5908 13 wie wie UH cord-015369-72cjogxz 5908 14 i -PRON- PRP cord-015369-72cjogxz 5908 15 m be VBP cord-015369-72cjogxz 5908 16 vorliegenden vorliegenden NNP cord-015369-72cjogxz 5908 17 Fall Fall NNP cord-015369-72cjogxz 5908 18 mit mit NNP cord-015369-72cjogxz 5908 19 multiplen multiplen NNP cord-015369-72cjogxz 5908 20 Karzinomen Karzinomen NNP cord-015369-72cjogxz 5908 21 , , , cord-015369-72cjogxz 5908 22 deutlich deutlich NNP cord-015369-72cjogxz 5908 23 erhöhen erhöhen NNP cord-015369-72cjogxz 5908 24 und und IN cord-015369-72cjogxz 5908 25 zu zu NNP cord-015369-72cjogxz 5908 26 vermeidbar vermeidbar NNP cord-015369-72cjogxz 5908 27 schweren schweren NNP cord-015369-72cjogxz 5908 28 Ausmaßen Ausmaßen NNP cord-015369-72cjogxz 5908 29 mit mit VBD cord-015369-72cjogxz 5908 30 sekundären sekundären JJ cord-015369-72cjogxz 5908 31 Krankheitsbildern Krankheitsbildern NNP cord-015369-72cjogxz 5908 32 führen führen NNP cord-015369-72cjogxz 5908 33 . . . cord-015369-72cjogxz 5909 1 Mit Mit NNP cord-015369-72cjogxz 5909 2 diesem diesem NNP cord-015369-72cjogxz 5909 3 aussergewöhnlichen aussergewöhnlichen NNP cord-015369-72cjogxz 5909 4 Fallbericht Fallbericht NNP cord-015369-72cjogxz 5909 5 wird wird NNP cord-015369-72cjogxz 5909 6 herausgehoben herausgehoben NNP cord-015369-72cjogxz 5909 7 , , , cord-015369-72cjogxz 5909 8 dass dass NNP cord-015369-72cjogxz 5909 9 aufgrund aufgrund NNP cord-015369-72cjogxz 5909 10 multilokulären multilokulären NNP cord-015369-72cjogxz 5909 11 , , , cord-015369-72cjogxz 5909 12 lokal lokal NNP cord-015369-72cjogxz 5909 13 fortgeschrittenen fortgeschrittenen NNP cord-015369-72cjogxz 5909 14 ( ( -LRB- cord-015369-72cjogxz 5909 15 Nþ Nþ NNP cord-015369-72cjogxz 5909 16 ) ) -RRB- cord-015369-72cjogxz 5909 17 Tumorstadiums Tumorstadiums NNP cord-015369-72cjogxz 5909 18 trotz trotz NNP cord-015369-72cjogxz 5909 19 erfolgreicher erfolgreicher NNP cord-015369-72cjogxz 5909 20 Operation Operation NNP cord-015369-72cjogxz 5909 21 und und IN cord-015369-72cjogxz 5909 22 stadiengerechter stadiengerechter NNP cord-015369-72cjogxz 5909 23 adjuvanter adjuvanter NNP cord-015369-72cjogxz 5909 24 Therapie Therapie NNP cord-015369-72cjogxz 5910 1 eine eine NNP cord-015369-72cjogxz 5910 2 engmaschige engmaschige NNP cord-015369-72cjogxz 5910 3 onkochirurgische onkochirurgische NNP cord-015369-72cjogxz 5911 1 Verlaufsbeobachtung Verlaufsbeobachtung NNP cord-015369-72cjogxz 5911 2 und und IN cord-015369-72cjogxz 5911 3 frühe frühe RB cord-015369-72cjogxz 5911 4 Inrervention Inrervention NNP cord-015369-72cjogxz 5911 5 bei bei NNP cord-015369-72cjogxz 5911 6 erhöhtem erhöhtem NNP cord-015369-72cjogxz 5912 1 Rezidivrisiko Rezidivrisiko NNP cord-015369-72cjogxz 5912 2 dringend dringend VBD cord-015369-72cjogxz 5912 3 verfolgt verfolgt NNP cord-015369-72cjogxz 5912 4 werden werden NNP cord-015369-72cjogxz 5912 5 muss muss NNP cord-015369-72cjogxz 5912 6 . . . cord-015369-72cjogxz 5913 1 Das Das NNP cord-015369-72cjogxz 5913 2 primäre primäre NNP cord-015369-72cjogxz 5913 3 amelanotische amelanotische NNP cord-015369-72cjogxz 5913 4 Melanom Melanom NNP cord-015369-72cjogxz 5913 5 des des NNP cord-015369-72cjogxz 5913 6 Rektums Rektums NNP cord-015369-72cjogxz 5913 7 Background Background NNP cord-015369-72cjogxz 5913 8 . . . cord-015369-72cjogxz 5914 1 A a DT cord-015369-72cjogxz 5914 2 new new JJ cord-015369-72cjogxz 5914 3 surgical surgical JJ cord-015369-72cjogxz 5914 4 technique technique NN cord-015369-72cjogxz 5914 5 , , , cord-015369-72cjogxz 5914 6 the the DT cord-015369-72cjogxz 5914 7 Perineal Perineal NNP cord-015369-72cjogxz 5914 8 Stapled Stapled NNP cord-015369-72cjogxz 5914 9 Prolapse Prolapse NNP cord-015369-72cjogxz 5914 10 resection resection NN cord-015369-72cjogxz 5914 11 ( ( -LRB- cord-015369-72cjogxz 5914 12 PSP PSP NNP cord-015369-72cjogxz 5914 13 ) ) -RRB- cord-015369-72cjogxz 5914 14 , , , cord-015369-72cjogxz 5914 15 for for IN cord-015369-72cjogxz 5914 16 external external JJ cord-015369-72cjogxz 5914 17 rectal rectal JJ cord-015369-72cjogxz 5914 18 prolapse prolapse NN cord-015369-72cjogxz 5914 19 was be VBD cord-015369-72cjogxz 5914 20 introduced introduce VBN cord-015369-72cjogxz 5914 21 by by IN cord-015369-72cjogxz 5914 22 a a DT cord-015369-72cjogxz 5914 23 feasibility feasibility NN cord-015369-72cjogxz 5914 24 study study NN cord-015369-72cjogxz 5914 25 in in IN cord-015369-72cjogxz 5914 26 2008 2008 CD cord-015369-72cjogxz 5914 27 . . . cord-015369-72cjogxz 5915 1 This this DT cord-015369-72cjogxz 5915 2 study study NN cord-015369-72cjogxz 5915 3 now now RB cord-015369-72cjogxz 5915 4 presents present VBZ cord-015369-72cjogxz 5915 5 the the DT cord-015369-72cjogxz 5915 6 first first JJ cord-015369-72cjogxz 5915 7 results result NNS cord-015369-72cjogxz 5915 8 of of IN cord-015369-72cjogxz 5915 9 a a DT cord-015369-72cjogxz 5915 10 larger large JJR cord-015369-72cjogxz 5915 11 patients patient NNS cord-015369-72cjogxz 5915 12 number number NN cord-015369-72cjogxz 5915 13 with with IN cord-015369-72cjogxz 5915 14 functional functional JJ cord-015369-72cjogxz 5915 15 outcome outcome NN cord-015369-72cjogxz 5915 16 in in IN cord-015369-72cjogxz 5915 17 a a DT cord-015369-72cjogxz 5915 18 midterm midterm NN cord-015369-72cjogxz 5915 19 follow follow NN cord-015369-72cjogxz 5915 20 - - HYPH cord-015369-72cjogxz 5915 21 up up NN cord-015369-72cjogxz 5915 22 . . . cord-015369-72cjogxz 5916 1 Methods method NNS cord-015369-72cjogxz 5916 2 . . . cord-015369-72cjogxz 5917 1 From from IN cord-015369-72cjogxz 5917 2 July July NNP cord-015369-72cjogxz 5917 3 2007 2007 CD cord-015369-72cjogxz 5917 4 to to IN cord-015369-72cjogxz 5917 5 December December NNP cord-015369-72cjogxz 5917 6 2008 2008 CD cord-015369-72cjogxz 5917 7 the the DT cord-015369-72cjogxz 5917 8 PSP PSP NNP cord-015369-72cjogxz 5917 9 was be VBD cord-015369-72cjogxz 5917 10 performed perform VBN cord-015369-72cjogxz 5917 11 on on IN cord-015369-72cjogxz 5917 12 28 28 CD cord-015369-72cjogxz 5917 13 patients patient NNS cord-015369-72cjogxz 5917 14 with with IN cord-015369-72cjogxz 5917 15 external external JJ cord-015369-72cjogxz 5917 16 rectal rectal JJ cord-015369-72cjogxz 5917 17 prolapse prolapse NN cord-015369-72cjogxz 5917 18 . . . cord-015369-72cjogxz 5918 1 The the DT cord-015369-72cjogxz 5918 2 prolapse prolapse NN cord-015369-72cjogxz 5918 3 was be VBD cord-015369-72cjogxz 5918 4 completely completely RB cord-015369-72cjogxz 5918 5 pulled pull VBN cord-015369-72cjogxz 5918 6 out out RP cord-015369-72cjogxz 5918 7 and and CC cord-015369-72cjogxz 5918 8 then then RB cord-015369-72cjogxz 5918 9 axially axially RB cord-015369-72cjogxz 5918 10 cut cut VBD cord-015369-72cjogxz 5918 11 open open JJ cord-015369-72cjogxz 5918 12 at at IN cord-015369-72cjogxz 5918 13 three three CD cord-015369-72cjogxz 5918 14 o'clock o'clock NN cord-015369-72cjogxz 5918 15 in in IN cord-015369-72cjogxz 5918 16 lithotomy lithotomy NN cord-015369-72cjogxz 5918 17 position position NN cord-015369-72cjogxz 5918 18 with with IN cord-015369-72cjogxz 5918 19 a a DT cord-015369-72cjogxz 5918 20 straight straight JJ cord-015369-72cjogxz 5918 21 stapler stapler NN cord-015369-72cjogxz 5918 22 . . . cord-015369-72cjogxz 5919 1 Finally finally RB cord-015369-72cjogxz 5919 2 the the DT cord-015369-72cjogxz 5919 3 prolapse prolapse NN cord-015369-72cjogxz 5919 4 was be VBD cord-015369-72cjogxz 5919 5 stepwise stepwise RB cord-015369-72cjogxz 5919 6 resected resect VBN cord-015369-72cjogxz 5919 7 with with IN cord-015369-72cjogxz 5919 8 the the DT cord-015369-72cjogxz 5919 9 curved curved JJ cord-015369-72cjogxz 5919 10 Contour Contour NNP cord-015369-72cjogxz 5919 11 + + CC cord-015369-72cjogxz 5919 12 Transtar Transtar NNP cord-015369-72cjogxz 5919 13 TM TM NNP cord-015369-72cjogxz 5919 14 stapler stapler NN cord-015369-72cjogxz 5919 15 at at IN cord-015369-72cjogxz 5919 16 prolapses prolapse NNS cord-015369-72cjogxz 5919 17 ' ' POS cord-015369-72cjogxz 5919 18 uptake uptake NN cord-015369-72cjogxz 5919 19 . . . cord-015369-72cjogxz 5920 1 Perioperative perioperative JJ cord-015369-72cjogxz 5920 2 morbidity morbidity NN cord-015369-72cjogxz 5920 3 and and CC cord-015369-72cjogxz 5920 4 functional functional JJ cord-015369-72cjogxz 5920 5 outcome outcome NN cord-015369-72cjogxz 5920 6 was be VBD cord-015369-72cjogxz 5920 7 prospectively prospectively RB cord-015369-72cjogxz 5920 8 documented document VBN cord-015369-72cjogxz 5920 9 by by IN cord-015369-72cjogxz 5920 10 different different JJ cord-015369-72cjogxz 5920 11 scores score NNS cord-015369-72cjogxz 5920 12 . . . cord-015369-72cjogxz 5921 1 Results result NNS cord-015369-72cjogxz 5921 2 . . . cord-015369-72cjogxz 5922 1 In in IN cord-015369-72cjogxz 5922 2 all all DT cord-015369-72cjogxz 5922 3 28 28 CD cord-015369-72cjogxz 5922 4 patients patient NNS cord-015369-72cjogxz 5922 5 , , , cord-015369-72cjogxz 5922 6 median median JJ cord-015369-72cjogxz 5922 7 age age NN cord-015369-72cjogxz 5922 8 82 82 CD cord-015369-72cjogxz 5922 9 years year NNS cord-015369-72cjogxz 5922 10 ( ( -LRB- cord-015369-72cjogxz 5922 11 range range VBP cord-015369-72cjogxz 5922 12 26 26 CD cord-015369-72cjogxz 5922 13 - - SYM cord-015369-72cjogxz 5922 14 93 93 CD cord-015369-72cjogxz 5922 15 ) ) -RRB- cord-015369-72cjogxz 5922 16 , , , cord-015369-72cjogxz 5922 17 PSP PSP NNP cord-015369-72cjogxz 5922 18 was be VBD cord-015369-72cjogxz 5922 19 performed perform VBN cord-015369-72cjogxz 5922 20 with with IN cord-015369-72cjogxz 5922 21 no no DT cord-015369-72cjogxz 5922 22 intraoperative intraoperative JJ cord-015369-72cjogxz 5922 23 complications complication NNS cord-015369-72cjogxz 5922 24 . . . cord-015369-72cjogxz 5923 1 14 14 CD cord-015369-72cjogxz 5923 2 % % NN cord-015369-72cjogxz 5923 3 postoperative postoperative JJ cord-015369-72cjogxz 5923 4 complications complication NNS cord-015369-72cjogxz 5923 5 occurred occur VBD cord-015369-72cjogxz 5923 6 , , , cord-015369-72cjogxz 5923 7 two two CD cord-015369-72cjogxz 5923 8 patients patient NNS cord-015369-72cjogxz 5923 9 had have VBD cord-015369-72cjogxz 5923 10 a a DT cord-015369-72cjogxz 5923 11 first first JJ cord-015369-72cjogxz 5923 12 degree degree NN cord-015369-72cjogxz 5923 13 complication complication NN cord-015369-72cjogxz 5923 14 ( ( -LRB- cord-015369-72cjogxz 5923 15 ¼ ¼ FW cord-015369-72cjogxz 5923 16 no no DT cord-015369-72cjogxz 5923 17 specific specific JJ cord-015369-72cjogxz 5923 18 treatment treatment NN cord-015369-72cjogxz 5923 19 necessary necessary JJ cord-015369-72cjogxz 5923 20 ) ) -RRB- cord-015369-72cjogxz 5923 21 , , , cord-015369-72cjogxz 5923 22 one one CD cord-015369-72cjogxz 5923 23 patient patient NN cord-015369-72cjogxz 5923 24 a a DT cord-015369-72cjogxz 5923 25 second second JJ cord-015369-72cjogxz 5923 26 degree degree NN cord-015369-72cjogxz 5923 27 ( ( -LRB- cord-015369-72cjogxz 5923 28 ¼ ¼ FW cord-015369-72cjogxz 5923 29 need need VB cord-015369-72cjogxz 5923 30 special special JJ cord-015369-72cjogxz 5923 31 medication medication NN cord-015369-72cjogxz 5923 32 ) ) -RRB- cord-015369-72cjogxz 5923 33 and and CC cord-015369-72cjogxz 5923 34 one one CD cord-015369-72cjogxz 5923 35 a a DT cord-015369-72cjogxz 5923 36 third third JJ cord-015369-72cjogxz 5923 37 degree degree NN cord-015369-72cjogxz 5923 38 ( ( -LRB- cord-015369-72cjogxz 5923 39 ¼ ¼ NNP cord-015369-72cjogxz 5923 40 interventional interventional JJ cord-015369-72cjogxz 5923 41 treatment treatment NN cord-015369-72cjogxz 5923 42 necessary necessary JJ cord-015369-72cjogxz 5923 43 ) ) -RRB- cord-015369-72cjogxz 5923 44 . . . cord-015369-72cjogxz 5924 1 No no DT cord-015369-72cjogxz 5924 2 mortality mortality NN cord-015369-72cjogxz 5924 3 . . . cord-015369-72cjogxz 5925 1 The the DT cord-015369-72cjogxz 5925 2 median median JJ cord-015369-72cjogxz 5925 3 operation operation NN cord-015369-72cjogxz 5925 4 time time NN cord-015369-72cjogxz 5925 5 was be VBD cord-015369-72cjogxz 5925 6 31 31 CD cord-015369-72cjogxz 5925 7 min min NN cord-015369-72cjogxz 5925 8 , , , cord-015369-72cjogxz 5925 9 the the DT cord-015369-72cjogxz 5925 10 median median JJ cord-015369-72cjogxz 5925 11 hospital hospital NN cord-015369-72cjogxz 5925 12 stay stay NN cord-015369-72cjogxz 5925 13 6 6 CD cord-015369-72cjogxz 5925 14 days day NNS cord-015369-72cjogxz 5925 15 ( ( -LRB- cord-015369-72cjogxz 5925 16 2 2 CD cord-015369-72cjogxz 5925 17 - - SYM cord-015369-72cjogxz 5925 18 29 29 CD cord-015369-72cjogxz 5925 19 ) ) -RRB- cord-015369-72cjogxz 5925 20 . . . cord-015369-72cjogxz 5926 1 In in IN cord-015369-72cjogxz 5926 2 two two CD cord-015369-72cjogxz 5926 3 patients patient NNS cord-015369-72cjogxz 5926 4 a a DT cord-015369-72cjogxz 5926 5 reccurence reccurence NN cord-015369-72cjogxz 5926 6 of of IN cord-015369-72cjogxz 5926 7 the the DT cord-015369-72cjogxz 5926 8 prolapse prolapse NN cord-015369-72cjogxz 5926 9 was be VBD cord-015369-72cjogxz 5926 10 observed observe VBN cord-015369-72cjogxz 5926 11 ( ( -LRB- cord-015369-72cjogxz 5926 12 7 7 CD cord-015369-72cjogxz 5926 13 % % NN cord-015369-72cjogxz 5926 14 ) ) -RRB- cord-015369-72cjogxz 5926 15 and and CC cord-015369-72cjogxz 5926 16 treated treat VBN cord-015369-72cjogxz 5926 17 with with IN cord-015369-72cjogxz 5926 18 a a DT cord-015369-72cjogxz 5926 19 second second JJ cord-015369-72cjogxz 5926 20 PSP PSP NNP cord-015369-72cjogxz 5926 21 procedure procedure NN cord-015369-72cjogxz 5926 22 . . . cord-015369-72cjogxz 5927 1 Functional functional JJ cord-015369-72cjogxz 5927 2 result result NN cord-015369-72cjogxz 5927 3 of of IN cord-015369-72cjogxz 5927 4 25 25 CD cord-015369-72cjogxz 5927 5 of of IN cord-015369-72cjogxz 5927 6 28 28 CD cord-015369-72cjogxz 5927 7 ( ( -LRB- cord-015369-72cjogxz 5927 8 89 89 CD cord-015369-72cjogxz 5927 9 % % NN cord-015369-72cjogxz 5927 10 ) ) -RRB- cord-015369-72cjogxz 5927 11 of of IN cord-015369-72cjogxz 5927 12 the the DT cord-015369-72cjogxz 5927 13 patients patient NNS cord-015369-72cjogxz 5927 14 were be VBD cord-015369-72cjogxz 5927 15 available available JJ cord-015369-72cjogxz 5927 16 after after IN cord-015369-72cjogxz 5927 17 a a DT cord-015369-72cjogxz 5927 18 median median JJ cord-015369-72cjogxz 5927 19 time time NN cord-015369-72cjogxz 5927 20 of of IN cord-015369-72cjogxz 5927 21 9 9 CD cord-015369-72cjogxz 5927 22 months month NNS cord-015369-72cjogxz 5927 23 ( ( -LRB- cord-015369-72cjogxz 5927 24 1 1 CD cord-015369-72cjogxz 5927 25 - - SYM cord-015369-72cjogxz 5927 26 17 17 CD cord-015369-72cjogxz 5927 27 ) ) -RRB- cord-015369-72cjogxz 5928 1 The the DT cord-015369-72cjogxz 5928 2 median median JJ cord-015369-72cjogxz 5928 3 reduction reduction NN cord-015369-72cjogxz 5928 4 of of IN cord-015369-72cjogxz 5928 5 the the DT cord-015369-72cjogxz 5928 6 Wexner Wexner NNP cord-015369-72cjogxz 5928 7 score score NN cord-015369-72cjogxz 5928 8 was be VBD cord-015369-72cjogxz 5928 9 from from IN cord-015369-72cjogxz 5928 10 17 17 CD cord-015369-72cjogxz 5928 11 ( ( -LRB- cord-015369-72cjogxz 5928 12 8 8 CD cord-015369-72cjogxz 5928 13 - - SYM cord-015369-72cjogxz 5928 14 20 20 CD cord-015369-72cjogxz 5928 15 ) ) -RRB- cord-015369-72cjogxz 5928 16 before before IN cord-015369-72cjogxz 5928 17 surgery surgery NN cord-015369-72cjogxz 5928 18 to to IN cord-015369-72cjogxz 5928 19 0.5 0.5 CD cord-015369-72cjogxz 5928 20 ( ( -LRB- cord-015369-72cjogxz 5928 21 0 0 CD cord-015369-72cjogxz 5928 22 - - SYM cord-015369-72cjogxz 5928 23 14 14 CD cord-015369-72cjogxz 5928 24 ) ) -RRB- cord-015369-72cjogxz 5928 25 postoperatively postoperatively RB cord-015369-72cjogxz 5928 26 , , , cord-015369-72cjogxz 5928 27 p p NN cord-015369-72cjogxz 5928 28 < < XX cord-015369-72cjogxz 5928 29 0.0001 0.0001 CD cord-015369-72cjogxz 5928 30 . . . cord-015369-72cjogxz 5929 1 Conclusions conclusion NNS cord-015369-72cjogxz 5929 2 . . . cord-015369-72cjogxz 5930 1 The the DT cord-015369-72cjogxz 5930 2 PSP PSP NNP cord-015369-72cjogxz 5930 3 is be VBZ cord-015369-72cjogxz 5930 4 an an DT cord-015369-72cjogxz 5930 5 elegant elegant JJ cord-015369-72cjogxz 5930 6 , , , cord-015369-72cjogxz 5930 7 fast fast JJ cord-015369-72cjogxz 5930 8 and and CC cord-015369-72cjogxz 5930 9 safe safe JJ cord-015369-72cjogxz 5930 10 procedure procedure NN cord-015369-72cjogxz 5930 11 , , , cord-015369-72cjogxz 5930 12 with with IN cord-015369-72cjogxz 5930 13 good good JJ cord-015369-72cjogxz 5930 14 functional functional JJ cord-015369-72cjogxz 5930 15 results result NNS cord-015369-72cjogxz 5930 16 . . . cord-015369-72cjogxz 5931 1 Colorectal colorectal JJ cord-015369-72cjogxz 5931 2 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 5931 3 in in IN cord-015369-72cjogxz 5931 4 heart heart NN cord-015369-72cjogxz 5931 5 transplant transplant NN cord-015369-72cjogxz 5931 6 recipients recipient NNS cord-015369-72cjogxz 5931 7 Background Background NNP cord-015369-72cjogxz 5931 8 . . . cord-015369-72cjogxz 5932 1 Conflicting conflicting JJ cord-015369-72cjogxz 5932 2 data datum NNS cord-015369-72cjogxz 5932 3 exist exist VBP cord-015369-72cjogxz 5932 4 whether whether IN cord-015369-72cjogxz 5932 5 patients patient NNS cord-015369-72cjogxz 5932 6 undergoing undergo VBG cord-015369-72cjogxz 5932 7 heart heart NN cord-015369-72cjogxz 5932 8 transplantation transplantation NN cord-015369-72cjogxz 5932 9 ( ( -LRB- cord-015369-72cjogxz 5932 10 HTX HTX NNP cord-015369-72cjogxz 5932 11 ) ) -RRB- cord-015369-72cjogxz 5932 12 are be VBP cord-015369-72cjogxz 5932 13 at at IN cord-015369-72cjogxz 5932 14 increased increase VBN cord-015369-72cjogxz 5932 15 risk risk NN cord-015369-72cjogxz 5932 16 for for IN cord-015369-72cjogxz 5932 17 developing develop VBG cord-015369-72cjogxz 5932 18 colorectal colorectal JJ cord-015369-72cjogxz 5932 19 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 5932 20 ( ( -LRB- cord-015369-72cjogxz 5932 21 CRC CRC NNP cord-015369-72cjogxz 5932 22 ) ) -RRB- cord-015369-72cjogxz 5932 23 . . . cord-015369-72cjogxz 5933 1 Specifically specifically RB cord-015369-72cjogxz 5933 2 , , , cord-015369-72cjogxz 5933 3 data datum NNS cord-015369-72cjogxz 5933 4 on on IN cord-015369-72cjogxz 5933 5 the the DT cord-015369-72cjogxz 5933 6 age age NN cord-015369-72cjogxz 5933 7 matched match VBN cord-015369-72cjogxz 5933 8 incidence incidence NN cord-015369-72cjogxz 5933 9 are be VBP cord-015369-72cjogxz 5933 10 rare rare JJ cord-015369-72cjogxz 5933 11 . . . cord-015369-72cjogxz 5934 1 Methods method NNS cord-015369-72cjogxz 5934 2 . . . cord-015369-72cjogxz 5935 1 The the DT cord-015369-72cjogxz 5935 2 Vienna Vienna NNP cord-015369-72cjogxz 5935 3 heart heart NN cord-015369-72cjogxz 5935 4 transplant transplant NN cord-015369-72cjogxz 5935 5 database database NN cord-015369-72cjogxz 5935 6 was be VBD cord-015369-72cjogxz 5935 7 queried query VBN cord-015369-72cjogxz 5935 8 to to TO cord-015369-72cjogxz 5935 9 configure configure VB cord-015369-72cjogxz 5935 10 a a DT cord-015369-72cjogxz 5935 11 list list NN cord-015369-72cjogxz 5935 12 of of IN cord-015369-72cjogxz 5935 13 eligible eligible JJ cord-015369-72cjogxz 5935 14 patients patient NNS cord-015369-72cjogxz 5935 15 . . . cord-015369-72cjogxz 5936 1 Exclusion exclusion NN cord-015369-72cjogxz 5936 2 criteria criterion NNS cord-015369-72cjogxz 5936 3 included include VBD cord-015369-72cjogxz 5936 4 : : : cord-015369-72cjogxz 5936 5 age age NN cord-015369-72cjogxz 5936 6 less less JJR cord-015369-72cjogxz 5936 7 than than IN cord-015369-72cjogxz 5936 8 35 35 CD cord-015369-72cjogxz 5936 9 years year NNS cord-015369-72cjogxz 5936 10 at at IN cord-015369-72cjogxz 5936 11 the the DT cord-015369-72cjogxz 5936 12 time time NN cord-015369-72cjogxz 5936 13 of of IN cord-015369-72cjogxz 5936 14 transplant transplant NN cord-015369-72cjogxz 5936 15 , , , cord-015369-72cjogxz 5936 16 diagnosis diagnosis NN cord-015369-72cjogxz 5936 17 of of IN cord-015369-72cjogxz 5936 18 colorectal colorectal JJ cord-015369-72cjogxz 5936 19 cancer cancer NN cord-015369-72cjogxz 5936 20 or or CC cord-015369-72cjogxz 5936 21 patient patient NN cord-015369-72cjogxz 5936 22 death death NN cord-015369-72cjogxz 5936 23 less less JJR cord-015369-72cjogxz 5936 24 than than IN cord-015369-72cjogxz 5936 25 12 12 CD cord-015369-72cjogxz 5936 26 month month NN cord-015369-72cjogxz 5936 27 posttransplant posttransplant NN cord-015369-72cjogxz 5936 28 , , , cord-015369-72cjogxz 5936 29 and and CC cord-015369-72cjogxz 5936 30 pretransplant pretransplant JJ cord-015369-72cjogxz 5936 31 history history NN cord-015369-72cjogxz 5936 32 of of IN cord-015369-72cjogxz 5936 33 colorectal colorectal JJ cord-015369-72cjogxz 5936 34 cancer cancer NN cord-015369-72cjogxz 5936 35 . . . cord-015369-72cjogxz 5937 1 Results result NNS cord-015369-72cjogxz 5937 2 . . . cord-015369-72cjogxz 5938 1 A a DT cord-015369-72cjogxz 5938 2 total total NN cord-015369-72cjogxz 5938 3 of of IN cord-015369-72cjogxz 5938 4 959 959 CD cord-015369-72cjogxz 5938 5 patients patient NNS cord-015369-72cjogxz 5938 6 with with IN cord-015369-72cjogxz 5938 7 HTX HTX NNP cord-015369-72cjogxz 5938 8 were be VBD cord-015369-72cjogxz 5938 9 eligible eligible JJ cord-015369-72cjogxz 5938 10 for for IN cord-015369-72cjogxz 5938 11 analysis analysis NN cord-015369-72cjogxz 5938 12 from from IN cord-015369-72cjogxz 5938 13 03/1984 03/1984 CD cord-015369-72cjogxz 5938 14 through through IN cord-015369-72cjogxz 5938 15 12/2007 12/2007 CD cord-015369-72cjogxz 5938 16 . . . cord-015369-72cjogxz 5939 1 The the DT cord-015369-72cjogxz 5939 2 mean mean JJ cord-015369-72cjogxz 5939 3 follow follow NN cord-015369-72cjogxz 5939 4 - - HYPH cord-015369-72cjogxz 5939 5 up up NN cord-015369-72cjogxz 5939 6 was be VBD cord-015369-72cjogxz 5939 7 7.2 7.2 CD cord-015369-72cjogxz 5939 8 years year NNS cord-015369-72cjogxz 5939 9 . . . cord-015369-72cjogxz 5940 1 We -PRON- PRP cord-015369-72cjogxz 5940 2 identified identify VBD cord-015369-72cjogxz 5940 3 11 11 CD cord-015369-72cjogxz 5940 4 cases case NNS cord-015369-72cjogxz 5940 5 of of IN cord-015369-72cjogxz 5940 6 CRC CRC NNP cord-015369-72cjogxz 5940 7 . . . cord-015369-72cjogxz 5941 1 Nine nine CD cord-015369-72cjogxz 5941 2 of of IN cord-015369-72cjogxz 5941 3 those those DT cord-015369-72cjogxz 5941 4 patients patient NNS cord-015369-72cjogxz 5941 5 were be VBD cord-015369-72cjogxz 5941 6 between between IN cord-015369-72cjogxz 5941 7 55 55 CD cord-015369-72cjogxz 5941 8 and and CC cord-015369-72cjogxz 5941 9 64 64 CD cord-015369-72cjogxz 5941 10 years year NNS cord-015369-72cjogxz 5941 11 of of IN cord-015369-72cjogxz 5941 12 age age NN cord-015369-72cjogxz 5941 13 at at IN cord-015369-72cjogxz 5941 14 diagnosis diagnosis NN cord-015369-72cjogxz 5941 15 of of IN cord-015369-72cjogxz 5941 16 CRC CRC NNP cord-015369-72cjogxz 5941 17 . . . cord-015369-72cjogxz 5942 1 Thus thus RB cord-015369-72cjogxz 5942 2 , , , cord-015369-72cjogxz 5942 3 the the DT cord-015369-72cjogxz 5942 4 incidence incidence NN cord-015369-72cjogxz 5942 5 of of IN cord-015369-72cjogxz 5942 6 CRC CRC NNP cord-015369-72cjogxz 5942 7 in in IN cord-015369-72cjogxz 5942 8 HTX HTX NNP cord-015369-72cjogxz 5942 9 recipients recipient NNS cord-015369-72cjogxz 5942 10 in in IN cord-015369-72cjogxz 5942 11 this this DT cord-015369-72cjogxz 5942 12 age age NN cord-015369-72cjogxz 5942 13 groups group NNS cord-015369-72cjogxz 5942 14 is be VBZ cord-015369-72cjogxz 5942 15 1.67/ 1.67/ CD cord-015369-72cjogxz 5942 16 1000 1000 CD cord-015369-72cjogxz 5942 17 , , , cord-015369-72cjogxz 5942 18 which which WDT cord-015369-72cjogxz 5942 19 is be VBZ cord-015369-72cjogxz 5942 20 9-fold 9-fold CD cord-015369-72cjogxz 5942 21 higher high JJR cord-015369-72cjogxz 5942 22 than than IN cord-015369-72cjogxz 5942 23 the the DT cord-015369-72cjogxz 5942 24 incidence incidence NN cord-015369-72cjogxz 5942 25 in in IN cord-015369-72cjogxz 5942 26 the the DT cord-015369-72cjogxz 5942 27 general general JJ cord-015369-72cjogxz 5942 28 Austrian austrian JJ cord-015369-72cjogxz 5942 29 population population NN cord-015369-72cjogxz 5942 30 for for IN cord-015369-72cjogxz 5942 31 CRC CRC NNP cord-015369-72cjogxz 5942 32 in in IN cord-015369-72cjogxz 5942 33 this this DT cord-015369-72cjogxz 5942 34 age age NN cord-015369-72cjogxz 5942 35 group group NN cord-015369-72cjogxz 5942 36 . . . cord-015369-72cjogxz 5943 1 The the DT cord-015369-72cjogxz 5943 2 latter latter JJ cord-015369-72cjogxz 5943 3 is be VBZ cord-015369-72cjogxz 5943 4 0.19/ 0.19/ CD cord-015369-72cjogxz 5943 5 1000 1000 CD cord-015369-72cjogxz 5943 6 , , , cord-015369-72cjogxz 5943 7 derived derive VBN cord-015369-72cjogxz 5943 8 from from IN cord-015369-72cjogxz 5943 9 Statistic Statistic NNP cord-015369-72cjogxz 5943 10 Austria Austria NNP cord-015369-72cjogxz 5943 11 . . . cord-015369-72cjogxz 5944 1 There there EX cord-015369-72cjogxz 5944 2 was be VBD cord-015369-72cjogxz 5944 3 no no DT cord-015369-72cjogxz 5944 4 difference difference NN cord-015369-72cjogxz 5944 5 in in IN cord-015369-72cjogxz 5944 6 the the DT cord-015369-72cjogxz 5944 7 incidence incidence NN cord-015369-72cjogxz 5944 8 of of IN cord-015369-72cjogxz 5944 9 CRC CRC NNP cord-015369-72cjogxz 5944 10 in in IN cord-015369-72cjogxz 5944 11 other other JJ cord-015369-72cjogxz 5944 12 age age NN cord-015369-72cjogxz 5944 13 groups group NNS cord-015369-72cjogxz 5944 14 between between IN cord-015369-72cjogxz 5944 15 the the DT cord-015369-72cjogxz 5944 16 Austrian austrian JJ cord-015369-72cjogxz 5944 17 population population NN cord-015369-72cjogxz 5944 18 and and CC cord-015369-72cjogxz 5944 19 HTX HTX NNP cord-015369-72cjogxz 5944 20 recipients recipient NNS cord-015369-72cjogxz 5944 21 . . . cord-015369-72cjogxz 5945 1 Median median JJ cord-015369-72cjogxz 5945 2 time time NN cord-015369-72cjogxz 5945 3 from from IN cord-015369-72cjogxz 5945 4 transplant transplant NN cord-015369-72cjogxz 5945 5 to to IN cord-015369-72cjogxz 5945 6 cancer cancer NN cord-015369-72cjogxz 5945 7 diagnosis diagnosis NN cord-015369-72cjogxz 5945 8 was be VBD cord-015369-72cjogxz 5945 9 7.3 7.3 CD cord-015369-72cjogxz 5945 10 years year NNS cord-015369-72cjogxz 5945 11 . . . cord-015369-72cjogxz 5946 1 The the DT cord-015369-72cjogxz 5946 2 median median JJ cord-015369-72cjogxz 5946 3 survival survival NN cord-015369-72cjogxz 5946 4 postcancer postcancer NN cord-015369-72cjogxz 5946 5 diagnosis diagnosis NN cord-015369-72cjogxz 5946 6 was be VBD cord-015369-72cjogxz 5946 7 3.9 3.9 CD cord-015369-72cjogxz 5946 8 years year NNS cord-015369-72cjogxz 5946 9 . . . cord-015369-72cjogxz 5947 1 Conclusions conclusion NNS cord-015369-72cjogxz 5947 2 . . . cord-015369-72cjogxz 5948 1 With with IN cord-015369-72cjogxz 5948 2 the the DT cord-015369-72cjogxz 5948 3 limitation limitation NN cord-015369-72cjogxz 5948 4 of of IN cord-015369-72cjogxz 5948 5 small small JJ cord-015369-72cjogxz 5948 6 numbers number NNS cord-015369-72cjogxz 5948 7 of of IN cord-015369-72cjogxz 5948 8 HTX HTX NNP cord-015369-72cjogxz 5948 9 recipients recipient NNS cord-015369-72cjogxz 5948 10 and and CC cord-015369-72cjogxz 5948 11 CRC CRC NNP cord-015369-72cjogxz 5948 12 available available JJ cord-015369-72cjogxz 5948 13 in in IN cord-015369-72cjogxz 5948 14 our -PRON- PRP$ cord-015369-72cjogxz 5948 15 study study NN cord-015369-72cjogxz 5948 16 , , , cord-015369-72cjogxz 5948 17 the the DT cord-015369-72cjogxz 5948 18 incidence incidence NN cord-015369-72cjogxz 5948 19 of of IN cord-015369-72cjogxz 5948 20 colorectal colorectal JJ cord-015369-72cjogxz 5948 21 adenocarcinoma adenocarcinoma NN cord-015369-72cjogxz 5948 22 in in IN cord-015369-72cjogxz 5948 23 heart heart NN cord-015369-72cjogxz 5948 24 transplant transplant NN cord-015369-72cjogxz 5948 25 recipients recipient NNS cord-015369-72cjogxz 5948 26 from from IN cord-015369-72cjogxz 5948 27 55 55 CD cord-015369-72cjogxz 5948 28 to to TO cord-015369-72cjogxz 5948 29 65 65 CD cord-015369-72cjogxz 5948 30 years year NNS cord-015369-72cjogxz 5948 31 appears appear VBZ cord-015369-72cjogxz 5948 32 to to TO cord-015369-72cjogxz 5948 33 be be VB cord-015369-72cjogxz 5948 34 markedly markedly RB cord-015369-72cjogxz 5948 35 increased increase VBN cord-015369-72cjogxz 5948 36 than than IN cord-015369-72cjogxz 5948 37 the the DT cord-015369-72cjogxz 5948 38 general general JJ cord-015369-72cjogxz 5948 39 population population NN cord-015369-72cjogxz 5948 40 . . . cord-015369-72cjogxz 5949 1 Our -PRON- PRP$ cord-015369-72cjogxz 5949 2 data datum NNS cord-015369-72cjogxz 5949 3 warrant warrant VBP cord-015369-72cjogxz 5949 4 an an DT cord-015369-72cjogxz 5949 5 intensified intensify VBN cord-015369-72cjogxz 5949 6 CRC crc NN cord-015369-72cjogxz 5949 7 screening screening NN cord-015369-72cjogxz 5949 8 program program NN cord-015369-72cjogxz 5949 9 for for IN cord-015369-72cjogxz 5949 10 HTX HTX NNP cord-015369-72cjogxz 5949 11 recipients recipient NNS cord-015369-72cjogxz 5949 12 in in IN cord-015369-72cjogxz 5949 13 this this DT cord-015369-72cjogxz 5949 14 age age NN cord-015369-72cjogxz 5949 15 group group NN cord-015369-72cjogxz 5949 16 . . . cord-015369-72cjogxz 5950 1 There there EX cord-015369-72cjogxz 5950 2 is be VBZ cord-015369-72cjogxz 5950 3 growing grow VBG cord-015369-72cjogxz 5950 4 evidence evidence NN cord-015369-72cjogxz 5950 5 that that IN cord-015369-72cjogxz 5950 6 chemotherapeutics chemotherapeutic NNS cord-015369-72cjogxz 5950 7 induce induce VBP cord-015369-72cjogxz 5950 8 an an DT cord-015369-72cjogxz 5950 9 inflammatory inflammatory JJ cord-015369-72cjogxz 5950 10 response response NN cord-015369-72cjogxz 5950 11 during during IN cord-015369-72cjogxz 5950 12 the the DT cord-015369-72cjogxz 5950 13 very very RB cord-015369-72cjogxz 5950 14 first first JJ cord-015369-72cjogxz 5950 15 course course NN cord-015369-72cjogxz 5950 16 of of IN cord-015369-72cjogxz 5950 17 treatment treatment NN cord-015369-72cjogxz 5950 18 . . . cord-015369-72cjogxz 5951 1 We -PRON- PRP cord-015369-72cjogxz 5951 2 investigated investigate VBD cord-015369-72cjogxz 5951 3 the the DT cord-015369-72cjogxz 5951 4 diagnostic diagnostic JJ cord-015369-72cjogxz 5951 5 history history NN cord-015369-72cjogxz 5951 6 of of IN cord-015369-72cjogxz 5951 7 patient patient NN cord-015369-72cjogxz 5951 8 with with IN cord-015369-72cjogxz 5951 9 either either CC cord-015369-72cjogxz 5951 10 breast breast NN cord-015369-72cjogxz 5951 11 or or CC cord-015369-72cjogxz 5951 12 colon colon NN cord-015369-72cjogxz 5951 13 cancer cancer NN cord-015369-72cjogxz 5951 14 . . . cord-015369-72cjogxz 5952 1 Due due IN cord-015369-72cjogxz 5952 2 to to IN cord-015369-72cjogxz 5952 3 their -PRON- PRP$ cord-015369-72cjogxz 5952 4 underlying underlying JJ cord-015369-72cjogxz 5952 5 disease disease NN cord-015369-72cjogxz 5952 6 they -PRON- PRP cord-015369-72cjogxz 5952 7 receive receive VBP cord-015369-72cjogxz 5952 8 different different JJ cord-015369-72cjogxz 5952 9 regimes regime NNS cord-015369-72cjogxz 5952 10 of of IN cord-015369-72cjogxz 5952 11 chemotherapeutic chemotherapeutic JJ cord-015369-72cjogxz 5952 12 treatment treatment NN cord-015369-72cjogxz 5952 13 . . . cord-015369-72cjogxz 5953 1 Our -PRON- PRP$ cord-015369-72cjogxz 5953 2 standard standard JJ cord-015369-72cjogxz 5953 3 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 5953 4 treatment treatment NN cord-015369-72cjogxz 5953 5 of of IN cord-015369-72cjogxz 5953 6 breast breast NN cord-015369-72cjogxz 5953 7 cancer cancer NN cord-015369-72cjogxz 5953 8 is be VBZ cord-015369-72cjogxz 5953 9 epirubicin epirubicin NNS cord-015369-72cjogxz 5953 10 and and CC cord-015369-72cjogxz 5953 11 docetaxel docetaxel JJ cord-015369-72cjogxz 5953 12 whereas whereas IN cord-015369-72cjogxz 5953 13 patients patient NNS cord-015369-72cjogxz 5953 14 suffering suffer VBG cord-015369-72cjogxz 5953 15 from from IN cord-015369-72cjogxz 5953 16 colon colon NN cord-015369-72cjogxz 5953 17 cancer cancer NN cord-015369-72cjogxz 5953 18 receive receive VBP cord-015369-72cjogxz 5953 19 oxaliplatin oxaliplatin NNP cord-015369-72cjogxz 5953 20 , , , cord-015369-72cjogxz 5953 21 irinotecan irinotecan NNP cord-015369-72cjogxz 5953 22 and and CC cord-015369-72cjogxz 5953 23 5-Fluoruracil 5-fluoruracil CD cord-015369-72cjogxz 5953 24 . . . cord-015369-72cjogxz 5954 1 We -PRON- PRP cord-015369-72cjogxz 5954 2 hypothesize hypothesize VBP cord-015369-72cjogxz 5954 3 that that IN cord-015369-72cjogxz 5954 4 chemotherapeutic chemotherapeutic JJ cord-015369-72cjogxz 5954 5 treatment treatment NN cord-015369-72cjogxz 5954 6 should should MD cord-015369-72cjogxz 5954 7 be be VB cord-015369-72cjogxz 5954 8 mirrored mirror VBN cord-015369-72cjogxz 5954 9 within within IN cord-015369-72cjogxz 5954 10 the the DT cord-015369-72cjogxz 5954 11 blood blood NN cord-015369-72cjogxz 5954 12 plasma plasma NN cord-015369-72cjogxz 5954 13 proteome proteome NN cord-015369-72cjogxz 5954 14 . . . cord-015369-72cjogxz 5955 1 For for IN cord-015369-72cjogxz 5955 2 this this DT cord-015369-72cjogxz 5955 3 reason reason NN cord-015369-72cjogxz 5955 4 , , , cord-015369-72cjogxz 5955 5 blood blood NN cord-015369-72cjogxz 5955 6 was be VBD cord-015369-72cjogxz 5955 7 taken take VBN cord-015369-72cjogxz 5955 8 from from IN cord-015369-72cjogxz 5955 9 both both DT cord-015369-72cjogxz 5955 10 groups group NNS cord-015369-72cjogxz 5955 11 on on IN cord-015369-72cjogxz 5955 12 the the DT cord-015369-72cjogxz 5955 13 day day NN cord-015369-72cjogxz 5955 14 before before IN cord-015369-72cjogxz 5955 15 and and CC cord-015369-72cjogxz 5955 16 2 2 CD cord-015369-72cjogxz 5955 17 - - SYM cord-015369-72cjogxz 5955 18 4 4 CD cord-015369-72cjogxz 5955 19 days day NNS cord-015369-72cjogxz 5955 20 after after IN cord-015369-72cjogxz 5955 21 receiving receive VBG cord-015369-72cjogxz 5955 22 the the DT cord-015369-72cjogxz 5955 23 first first JJ cord-015369-72cjogxz 5955 24 course course NN cord-015369-72cjogxz 5955 25 of of IN cord-015369-72cjogxz 5955 26 chemotherapy chemotherapy NN cord-015369-72cjogxz 5955 27 . . . cord-015369-72cjogxz 5956 1 Plasma plasma NN cord-015369-72cjogxz 5956 2 proteomic proteomic JJ cord-015369-72cjogxz 5956 3 analysis analysis NN cord-015369-72cjogxz 5956 4 using use VBG cord-015369-72cjogxz 5956 5 2D 2D NNP cord-015369-72cjogxz 5956 6 - - HYPH cord-015369-72cjogxz 5956 7 Differential differential NN cord-015369-72cjogxz 5956 8 in in IN cord-015369-72cjogxz 5956 9 gel gel NN cord-015369-72cjogxz 5956 10 electrophoresis electrophoresis NN cord-015369-72cjogxz 5956 11 ( ( -LRB- cord-015369-72cjogxz 5956 12 DIGE DIGE NNP cord-015369-72cjogxz 5956 13 ) ) -RRB- cord-015369-72cjogxz 5956 14 was be VBD cord-015369-72cjogxz 5956 15 performed perform VBN cord-015369-72cjogxz 5956 16 . . . cord-015369-72cjogxz 5957 1 Differentially differentially RB cord-015369-72cjogxz 5957 2 expressed express VBN cord-015369-72cjogxz 5957 3 proteins protein NNS cord-015369-72cjogxz 5957 4 were be VBD cord-015369-72cjogxz 5957 5 identified identify VBN cord-015369-72cjogxz 5957 6 by by IN cord-015369-72cjogxz 5957 7 mass mass NN cord-015369-72cjogxz 5957 8 spectrometry spectrometry NN cord-015369-72cjogxz 5957 9 . . . cord-015369-72cjogxz 5958 1 Using use VBG cord-015369-72cjogxz 5958 2 investigations investigation NNS cord-015369-72cjogxz 5958 3 of of IN cord-015369-72cjogxz 5958 4 plasma plasma NN cord-015369-72cjogxz 5958 5 proteome proteome NN cord-015369-72cjogxz 5958 6 analysis analysis NN cord-015369-72cjogxz 5958 7 we -PRON- PRP cord-015369-72cjogxz 5958 8 validated validate VBD cord-015369-72cjogxz 5958 9 our -PRON- PRP$ cord-015369-72cjogxz 5958 10 findings finding NNS cord-015369-72cjogxz 5958 11 using use VBG cord-015369-72cjogxz 5958 12 Western western JJ cord-015369-72cjogxz 5958 13 blot blot NN cord-015369-72cjogxz 5958 14 . . . cord-015369-72cjogxz 5959 1 Twenty twenty CD cord-015369-72cjogxz 5959 2 - - HYPH cord-015369-72cjogxz 5959 3 six six CD cord-015369-72cjogxz 5959 4 out out IN cord-015369-72cjogxz 5959 5 of of IN cord-015369-72cjogxz 5959 6 577 577 CD cord-015369-72cjogxz 5959 7 protein protein NN cord-015369-72cjogxz 5959 8 spots spot NNS cord-015369-72cjogxz 5959 9 showed show VBD cord-015369-72cjogxz 5959 10 a a DT cord-015369-72cjogxz 5959 11 more more JJR cord-015369-72cjogxz 5959 12 than than IN cord-015369-72cjogxz 5959 13 1.4 1.4 CD cord-015369-72cjogxz 5959 14 fold fold NN cord-015369-72cjogxz 5959 15 ( ( -LRB- cord-015369-72cjogxz 5959 16 p p NN cord-015369-72cjogxz 5959 17 < < XX cord-015369-72cjogxz 5959 18 0.05 0.05 CD cord-015369-72cjogxz 5959 19 ) ) -RRB- cord-015369-72cjogxz 5959 20 change change NN cord-015369-72cjogxz 5959 21 within within IN cord-015369-72cjogxz 5959 22 4 4 CD cord-015369-72cjogxz 5959 23 days day NNS cord-015369-72cjogxz 5959 24 of of IN cord-015369-72cjogxz 5959 25 chemotherapy chemotherapy NN cord-015369-72cjogxz 5959 26 , , , cord-015369-72cjogxz 5959 27 including include VBG cord-015369-72cjogxz 5959 28 complement complement NN cord-015369-72cjogxz 5959 29 factors factor NNS cord-015369-72cjogxz 5959 30 C1 C1 NNP cord-015369-72cjogxz 5959 31 , , , cord-015369-72cjogxz 5959 32 C3 C3 NNP cord-015369-72cjogxz 5959 33 and and CC cord-015369-72cjogxz 5959 34 C4 C4 NNP cord-015369-72cjogxz 5959 35 , , , cord-015369-72cjogxz 5959 36 alpha2HS alpha2hs JJ cord-015369-72cjogxz 5959 37 glycoprotein glycoprotein NN cord-015369-72cjogxz 5959 38 and and CC cord-015369-72cjogxz 5959 39 alpha alpha NN cord-015369-72cjogxz 5959 40 1-anti 1-anti CD cord-015369-72cjogxz 5959 41 chymotrypsin chymotrypsin NN cord-015369-72cjogxz 5959 42 in in IN cord-015369-72cjogxz 5959 43 the the DT cord-015369-72cjogxz 5959 44 breast breast NN cord-015369-72cjogxz 5959 45 cancer cancer NN cord-015369-72cjogxz 5959 46 collective collective NN cord-015369-72cjogxz 5959 47 . . . cord-015369-72cjogxz 5960 1 In in IN cord-015369-72cjogxz 5960 2 contrast contrast NN cord-015369-72cjogxz 5960 3 , , , cord-015369-72cjogxz 5960 4 in in IN cord-015369-72cjogxz 5960 5 colon colon NN cord-015369-72cjogxz 5960 6 cancer cancer NN cord-015369-72cjogxz 5960 7 patients patient NNS cord-015369-72cjogxz 5960 8 the the DT cord-015369-72cjogxz 5960 9 expression expression NN cord-015369-72cjogxz 5960 10 level level NN cord-015369-72cjogxz 5960 11 of of IN cord-015369-72cjogxz 5960 12 only only RB cord-015369-72cjogxz 5960 13 5 5 CD cord-015369-72cjogxz 5960 14 out out IN cord-015369-72cjogxz 5960 15 of of IN cord-015369-72cjogxz 5960 16 471 471 CD cord-015369-72cjogxz 5960 17 proteins protein NNS cord-015369-72cjogxz 5960 18 was be VBD cord-015369-72cjogxz 5960 19 affected affect VBN cord-015369-72cjogxz 5960 20 by by IN cord-015369-72cjogxz 5960 21 the the DT cord-015369-72cjogxz 5960 22 treatment treatment NN cord-015369-72cjogxz 5960 23 . . . cord-015369-72cjogxz 5961 1 Future future JJ cord-015369-72cjogxz 5961 2 investigations investigation NNS cord-015369-72cjogxz 5961 3 will will MD cord-015369-72cjogxz 5961 4 show show VB cord-015369-72cjogxz 5961 5 whether whether IN cord-015369-72cjogxz 5961 6 this this DT cord-015369-72cjogxz 5961 7 difference difference NN cord-015369-72cjogxz 5961 8 in in IN cord-015369-72cjogxz 5961 9 the the DT cord-015369-72cjogxz 5961 10 treatment treatment NN cord-015369-72cjogxz 5961 11 induced induce VBD cord-015369-72cjogxz 5961 12 protein protein NN cord-015369-72cjogxz 5961 13 expression expression NN cord-015369-72cjogxz 5961 14 changes change NNS cord-015369-72cjogxz 5961 15 were be VBD cord-015369-72cjogxz 5961 16 related relate VBN cord-015369-72cjogxz 5961 17 on on IN cord-015369-72cjogxz 5961 18 different different JJ cord-015369-72cjogxz 5961 19 chemotherapeutic chemotherapeutic JJ cord-015369-72cjogxz 5961 20 treatment treatment NN cord-015369-72cjogxz 5961 21 or or CC cord-015369-72cjogxz 5961 22 different different JJ cord-015369-72cjogxz 5961 23 patient patient NN cord-015369-72cjogxz 5961 24 collective collective NN cord-015369-72cjogxz 5961 25 . . . cord-015369-72cjogxz 5962 1 Lösliches Lösliches NNP cord-015369-72cjogxz 5962 2 Cytokeratin Cytokeratin NNP cord-015369-72cjogxz 5962 3 18-M65-hat 18-m65-hat CD cord-015369-72cjogxz 5963 1 Potential potential JJ cord-015369-72cjogxz 5963 2 als als NN cord-015369-72cjogxz 5964 1 postoperativer postoperativer NNP cord-015369-72cjogxz 5964 2 Surrogate Surrogate NNP cord-015369-72cjogxz 5964 3 Marker Marker NNP cord-015369-72cjogxz 5964 4 für für IN cord-015369-72cjogxz 5964 5 den den NNP cord-015369-72cjogxz 5964 6 Nachweis Nachweis NNP cord-015369-72cjogxz 5964 7 einer einer NNP cord-015369-72cjogxz 5964 8 systemischen systemischen NNS cord-015369-72cjogxz 5965 1 Erkrankung Erkrankung NNP cord-015369-72cjogxz 5965 2 beim beim NNP cord-015369-72cjogxz 5965 3 kolorektalen kolorektalen NNP cord-015369-72cjogxz 5965 4 Karzinom Karzinom NNP cord-015369-72cjogxz 5965 5 Bei Bei NNP cord-015369-72cjogxz 5965 6 einem einem NNP cord-015369-72cjogxz 5965 7 81 81 CD cord-015369-72cjogxz 5965 8 Jahre Jahre NNP cord-015369-72cjogxz 5965 9 alten alten NNP cord-015369-72cjogxz 5965 10 männlichen männlichen NNP cord-015369-72cjogxz 5965 11 Patienten Patienten NNP cord-015369-72cjogxz 5965 12 trat trat NN cord-015369-72cjogxz 5966 1 nach nach NNP cord-015369-72cjogxz 5966 2 einer einer NNP cord-015369-72cjogxz 5966 3 notwendigen notwendigen NNP cord-015369-72cjogxz 5966 4 parenteralen parenteralen NNP cord-015369-72cjogxz 5966 5 Infusionstherapie Infusionstherapie NNP cord-015369-72cjogxz 5966 6 am be VBP cord-015369-72cjogxz 5966 7 Handrücken Handrücken NNP cord-015369-72cjogxz 5966 8 eine eine NNP cord-015369-72cjogxz 5966 9 Phlegmone Phlegmone NNP cord-015369-72cjogxz 5966 10 auf auf NNP cord-015369-72cjogxz 5966 11 , , , cord-015369-72cjogxz 5966 12 die die VBP cord-015369-72cjogxz 5966 13 primär primär NNP cord-015369-72cjogxz 5966 14 unbehandelt unbehandelt NNP cord-015369-72cjogxz 5966 15 blieb blieb NNP cord-015369-72cjogxz 5966 16 . . . cord-015369-72cjogxz 5967 1 Es Es NNP cord-015369-72cjogxz 5967 2 kam kam NNP cord-015369-72cjogxz 5967 3 jedoch jedoch NNP cord-015369-72cjogxz 5967 4 zu zu NNP cord-015369-72cjogxz 5967 5 einem einem NNP cord-015369-72cjogxz 5967 6 Fortschreiten Fortschreiten NNP cord-015369-72cjogxz 5967 7 der der NNP cord-015369-72cjogxz 5967 8 Infektion Infektion NNP cord-015369-72cjogxz 5967 9 . . . cord-015369-72cjogxz 5968 1 Schließlich Schließlich NNP cord-015369-72cjogxz 5968 2 musste musste NNP cord-015369-72cjogxz 5969 1 eine eine NNP cord-015369-72cjogxz 5969 2 Incision Incision NNP cord-015369-72cjogxz 5969 3 durchgeführt durchgeführt NN cord-015369-72cjogxz 5969 4 werden werden NNP cord-015369-72cjogxz 5969 5 , , , cord-015369-72cjogxz 5969 6 trotz trotz NNP cord-015369-72cjogxz 5969 7 der der NNP cord-015369-72cjogxz 5969 8 Incision Incision NNP cord-015369-72cjogxz 5970 1 kam kam NNP cord-015369-72cjogxz 5970 2 es es NNP cord-015369-72cjogxz 5971 1 jedoch jedoch NNP cord-015369-72cjogxz 5971 2 zu zu NNP cord-015369-72cjogxz 5972 1 einem einem NNP cord-015369-72cjogxz 5972 2 handtellergroßen handtellergroßen NNP cord-015369-72cjogxz 5972 3 Hautdefekt Hautdefekt NNP cord-015369-72cjogxz 5972 4 am be VBP cord-015369-72cjogxz 5973 1 Handrücken Handrücken NNP cord-015369-72cjogxz 5973 2 rechts rechts NNP cord-015369-72cjogxz 5973 3 mit mit NNP cord-015369-72cjogxz 5973 4 konsekutivem konsekutivem NNP cord-015369-72cjogxz 5973 5 Abriss Abriss NNP cord-015369-72cjogxz 5973 6 sämtlicher sämtlicher NNP cord-015369-72cjogxz 5973 7 Strecksehnen Strecksehnen NNP cord-015369-72cjogxz 5973 8 . . . cord-015369-72cjogxz 5974 1 Der Der NNP cord-015369-72cjogxz 5974 2 Patient Patient NNP cord-015369-72cjogxz 5974 3 war war NN cord-015369-72cjogxz 5974 4 in in IN cord-015369-72cjogxz 5974 5 stark stark JJ cord-015369-72cjogxz 5974 6 reduziertem reduziertem NN cord-015369-72cjogxz 5974 7 Allgemeinzustand Allgemeinzustand NNP cord-015369-72cjogxz 5975 1 ( ( -LRB- cord-015369-72cjogxz 5975 2 Zustand Zustand NNP cord-015369-72cjogxz 5975 3 nach nach NNP cord-015369-72cjogxz 5975 4 Beckenfraktur Beckenfraktur NNP cord-015369-72cjogxz 5975 5 , , , cord-015369-72cjogxz 5975 6 postantibiotische postantibiotische NNP cord-015369-72cjogxz 5975 7 Enterocollitis Enterocollitis NNP cord-015369-72cjogxz 5975 8 , , , cord-015369-72cjogxz 5975 9 Demenz Demenz NNP cord-015369-72cjogxz 5975 10 ) ) -RRB- cord-015369-72cjogxz 5975 11 . . . cord-015369-72cjogxz 5976 1 Trotz Trotz NNP cord-015369-72cjogxz 5976 2 des des FW cord-015369-72cjogxz 5976 3 schlechten schlechten NNP cord-015369-72cjogxz 5976 4 Allgemeinzustandes Allgemeinzustandes NNP cord-015369-72cjogxz 5976 5 musste musste NNP cord-015369-72cjogxz 5977 1 eine eine NNP cord-015369-72cjogxz 5977 2 Rekonstruktion Rekonstruktion NNP cord-015369-72cjogxz 5977 3 der der NNP cord-015369-72cjogxz 5977 4 Sehnen Sehnen NNP cord-015369-72cjogxz 5977 5 und und IN cord-015369-72cjogxz 5977 6 Deckung Deckung NNP cord-015369-72cjogxz 5977 7 des des FW cord-015369-72cjogxz 5977 8 Hautdefektes Hautdefektes NNP cord-015369-72cjogxz 5977 9 durchgeführt durchgeführt NN cord-015369-72cjogxz 5978 1 werden werden NNP cord-015369-72cjogxz 5978 2 , , , cord-015369-72cjogxz 5978 3 da da NNP cord-015369-72cjogxz 5978 4 sonst sonst NNP cord-015369-72cjogxz 5978 5 der der NNP cord-015369-72cjogxz 5978 6 Patient Patient NNP cord-015369-72cjogxz 5978 7 in in IN cord-015369-72cjogxz 5978 8 weiterer weiterer NNP cord-015369-72cjogxz 5978 9 Folge Folge NNP cord-015369-72cjogxz 5978 10 sich sich NNP cord-015369-72cjogxz 5978 11 selbständig selbständig NNP cord-015369-72cjogxz 5979 1 nicht nicht NNP cord-015369-72cjogxz 5979 2 mehr mehr NNP cord-015369-72cjogxz 5979 3 versorgen versorgen NNP cord-015369-72cjogxz 5979 4 hätte hätte NNP cord-015369-72cjogxz 5979 5 können können NNP cord-015369-72cjogxz 5979 6 . . . cord-015369-72cjogxz 5980 1 Es Es NNP cord-015369-72cjogxz 5980 2 erfolgte erfolgte NN cord-015369-72cjogxz 5980 3 in in IN cord-015369-72cjogxz 5980 4 vitaler vitaler NNP cord-015369-72cjogxz 5980 5 Indikation Indikation NNP cord-015369-72cjogxz 5980 6 die die VBP cord-015369-72cjogxz 5980 7 Rekonstruktion Rekonstruktion NNP cord-015369-72cjogxz 5980 8 sämtlicher sämtlicher NN cord-015369-72cjogxz 5981 1 Strecksehnen Strecksehnen NNP cord-015369-72cjogxz 5981 2 durch durch NNP cord-015369-72cjogxz 5981 3 Strecksehnenplastik Strecksehnenplastik NNP cord-015369-72cjogxz 5982 1 und und NNP cord-015369-72cjogxz 5982 2 die die VB cord-015369-72cjogxz 5983 1 Deckung Deckung NNP cord-015369-72cjogxz 5983 2 des des FW cord-015369-72cjogxz 5983 3 Hautdefektes Hautdefektes NNP cord-015369-72cjogxz 5983 4 durch durch NNP cord-015369-72cjogxz 5983 5 einen einen JJ cord-015369-72cjogxz 5983 6 gestillten gestillten JJ cord-015369-72cjogxz 5983 7 Hautlappen Hautlappen NNP cord-015369-72cjogxz 5983 8 . . . cord-015369-72cjogxz 5984 1 Gleichzeitig Gleichzeitig NNP cord-015369-72cjogxz 5984 2 musste musste NNP cord-015369-72cjogxz 5985 1 eine eine NNP cord-015369-72cjogxz 5985 2 antibiotische antibiotische NNP cord-015369-72cjogxz 5985 3 Therapie Therapie NNP cord-015369-72cjogxz 5985 4 mit mit NNP cord-015369-72cjogxz 5985 5 Metronidacol Metronidacol NNP cord-015369-72cjogxz 5985 6 durchgeführt durchgeführt NN cord-015369-72cjogxz 5985 7 werden werden NNP cord-015369-72cjogxz 5985 8 . . . cord-015369-72cjogxz 5986 1 Es Es NNP cord-015369-72cjogxz 5986 2 erfolgte erfolgte NN cord-015369-72cjogxz 5986 3 anschließend anschließend NN cord-015369-72cjogxz 5987 1 eine eine NNP cord-015369-72cjogxz 5987 2 Ruhigstellung Ruhigstellung NNP cord-015369-72cjogxz 5987 3 und und NNP cord-015369-72cjogxz 5987 4 durch durch NNP cord-015369-72cjogxz 5987 5 diese diese NNP cord-015369-72cjogxz 5987 6 Therapie Therapie NNP cord-015369-72cjogxz 5987 7 konnte konnte NNP cord-015369-72cjogxz 5987 8 eine eine NNP cord-015369-72cjogxz 5988 1 völlige völlige NNP cord-015369-72cjogxz 5988 2 Wiederherstellung Wiederherstellung NNP cord-015369-72cjogxz 5988 3 der der NNP cord-015369-72cjogxz 5988 4 Handfunktion Handfunktion NNP cord-015369-72cjogxz 5988 5 erzielt erzielt NNS cord-015369-72cjogxz 5988 6 werden werden NNP cord-015369-72cjogxz 5988 7 . . . cord-015369-72cjogxz 5989 1 Zusätzlich Zusätzlich NNP cord-015369-72cjogxz 5989 2 kam kam NNP cord-015369-72cjogxz 5989 3 es es XX cord-015369-72cjogxz 5989 4 zu zu NNP cord-015369-72cjogxz 5989 5 einer einer NNP cord-015369-72cjogxz 5990 1 Besserung Besserung NNP cord-015369-72cjogxz 5990 2 des des NNP cord-015369-72cjogxz 5990 3 Allgemeinzustandes Allgemeinzustandes NNP cord-015369-72cjogxz 5990 4 und und NNP cord-015369-72cjogxz 5990 5 der der NNP cord-015369-72cjogxz 5990 6 Patient Patient NNP cord-015369-72cjogxz 5990 7 kann kann NNP cord-015369-72cjogxz 5990 8 sich sich NNP cord-015369-72cjogxz 5990 9 nun nun NNP cord-015369-72cjogxz 5990 10 selbst selbst NNP cord-015369-72cjogxz 5990 11 versorgen versorgen NNP cord-015369-72cjogxz 5990 12 . . . cord-015369-72cjogxz 5991 1 Es Es NNP cord-015369-72cjogxz 5991 2 wird wird NNP cord-015369-72cjogxz 5991 3 auf auf NNP cord-015369-72cjogxz 5991 4 die die VBP cord-015369-72cjogxz 5992 1 Therapie Therapie NNP cord-015369-72cjogxz 5992 2 und und NNP cord-015369-72cjogxz 5992 3 auf auf NNP cord-015369-72cjogxz 5992 4 die die VBP cord-015369-72cjogxz 5993 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 5993 2 eingegangen eingegangen NNP cord-015369-72cjogxz 5993 3 . . . cord-015369-72cjogxz 5994 1 Neuropathien Neuropathien NNP cord-015369-72cjogxz 5994 2 der der NNP cord-015369-72cjogxz 5994 3 oberen oberen NNP cord-015369-72cjogxz 5995 1 Extremität Extremität NNP cord-015369-72cjogxz 5995 2 präsentieren präsentieren NNP cord-015369-72cjogxz 5995 3 klinisch klinisch NNP cord-015369-72cjogxz 5996 1 oft oft NNP cord-015369-72cjogxz 5996 2 mit mit NNP cord-015369-72cjogxz 5996 3 sehr sehr NNP cord-015369-72cjogxz 5996 4 ähnlichen ähnlichen NNP cord-015369-72cjogxz 5996 5 Symptomen Symptomen NNP cord-015369-72cjogxz 5996 6 , , , cord-015369-72cjogxz 5996 7 obwohl obwohl NNP cord-015369-72cjogxz 5996 8 oft oft VBD cord-015369-72cjogxz 5996 9 sehr sehr JJ cord-015369-72cjogxz 5996 10 unterschiedliche unterschiedliche NN cord-015369-72cjogxz 5996 11 Ä Ä NNP cord-015369-72cjogxz 5996 12 tiologien tiologien NNP cord-015369-72cjogxz 5996 13 zu zu NNP cord-015369-72cjogxz 5996 14 einem einem NNP cord-015369-72cjogxz 5996 15 eng eng NNP cord-015369-72cjogxz 5996 16 gefassten gefassten NNP cord-015369-72cjogxz 5996 17 klinischen klinischen NNP cord-015369-72cjogxz 5996 18 Zustandsbild Zustandsbild NNP cord-015369-72cjogxz 5996 19 gefü gefü NN cord-015369-72cjogxz 5996 20 hrt hrt NNP cord-015369-72cjogxz 5996 21 haben haben NNP cord-015369-72cjogxz 5996 22 können können NNP cord-015369-72cjogxz 5996 23 . . . cord-015369-72cjogxz 5997 1 Dies die VBZ cord-015369-72cjogxz 5997 2 kann kann NNP cord-015369-72cjogxz 5997 3 entweder entweder NNP cord-015369-72cjogxz 5997 4 zu zu NNP cord-015369-72cjogxz 5997 5 einer einer NNP cord-015369-72cjogxz 5997 6 glatten glatten NNP cord-015369-72cjogxz 5998 1 Fehldiagnose Fehldiagnose NNP cord-015369-72cjogxz 5998 2 und und IN cord-015369-72cjogxz 5998 3 entsprechender entsprechender NN cord-015369-72cjogxz 5998 4 Fehlbehandlung Fehlbehandlung NNP cord-015369-72cjogxz 5999 1 fü fü IN cord-015369-72cjogxz 6000 1 hren hren NNP cord-015369-72cjogxz 6000 2 oder oder NNP cord-015369-72cjogxz 6000 3 den den NNP cord-015369-72cjogxz 6000 4 behandelnden behandelnden NNP cord-015369-72cjogxz 6000 5 Arzt Arzt NNP cord-015369-72cjogxz 6000 6 in in IN cord-015369-72cjogxz 6000 7 ein ein NNP cord-015369-72cjogxz 6000 8 diagnostisches diagnostisches NNP cord-015369-72cjogxz 6000 9 Dilemma Dilemma NNP cord-015369-72cjogxz 6000 10 bringen bringen NNP cord-015369-72cjogxz 6000 11 . . . cord-015369-72cjogxz 6001 1 Bei Bei NNP cord-015369-72cjogxz 6001 2 einer einer NNP cord-015369-72cjogxz 6002 1 klaren klaren NNP cord-015369-72cjogxz 6002 2 Anamnese Anamnese NNP cord-015369-72cjogxz 6002 3 , , , cord-015369-72cjogxz 6002 4 welche welche NNP cord-015369-72cjogxz 6002 5 eine eine NNP cord-015369-72cjogxz 6002 6 mechanische mechanische NNP cord-015369-72cjogxz 6002 7 Ursache Ursache NNP cord-015369-72cjogxz 6002 8 , , , cord-015369-72cjogxz 6002 9 wie wie NNP cord-015369-72cjogxz 6002 10 Trauma Trauma NNP cord-015369-72cjogxz 6002 11 oder oder NN cord-015369-72cjogxz 6002 12 chronische chronische NNP cord-015369-72cjogxz 6002 13 Kompression Kompression NNP cord-015369-72cjogxz 6002 14 nahe nahe NNP cord-015369-72cjogxz 6002 15 legt legt NNP cord-015369-72cjogxz 6002 16 , , , cord-015369-72cjogxz 6002 17 ist ist NNP cord-015369-72cjogxz 6002 18 natürlich natürlich NNP cord-015369-72cjogxz 6002 19 die die VBP cord-015369-72cjogxz 6002 20 Therapie Therapie NNP cord-015369-72cjogxz 6002 21 klar klar NNP cord-015369-72cjogxz 6002 22 vorgegeben vorgegeben NNP cord-015369-72cjogxz 6002 23 . . . cord-015369-72cjogxz 6003 1 Bei Bei NNP cord-015369-72cjogxz 6003 2 Patienten Patienten NNP cord-015369-72cjogxz 6003 3 mit mit XX cord-015369-72cjogxz 6004 1 unklarer unklarer NNP cord-015369-72cjogxz 6004 2 Ä Ä NNP cord-015369-72cjogxz 6004 3 tiologie tiologie NNP cord-015369-72cjogxz 6005 1 und und NNP cord-015369-72cjogxz 6006 1 klinischer klinischer NNP cord-015369-72cjogxz 6006 2 Präsentation Präsentation NNP cord-015369-72cjogxz 6006 3 sollte sollte NNP cord-015369-72cjogxz 6006 4 auch auch NNP cord-015369-72cjogxz 6006 5 an an DT cord-015369-72cjogxz 6006 6 den den NN cord-015369-72cjogxz 6006 7 seltenen seltenen NNP cord-015369-72cjogxz 6006 8 Fall Fall NNP cord-015369-72cjogxz 6006 9 einer einer NNP cord-015369-72cjogxz 6006 10 isolierten isolierten NNP cord-015369-72cjogxz 6006 11 Neuritis Neuritis NNP cord-015369-72cjogxz 6006 12 gedacht gedacht NNP cord-015369-72cjogxz 6006 13 werden werden NNP cord-015369-72cjogxz 6006 14 . . . cord-015369-72cjogxz 6007 1 Diese Diese NNP cord-015369-72cjogxz 6007 2 spontan spontan NNP cord-015369-72cjogxz 6007 3 auftretenden auftretenden VBD cord-015369-72cjogxz 6007 4 Lähmungen Lähmungen NNP cord-015369-72cjogxz 6007 5 können können NNP cord-015369-72cjogxz 6007 6 auf auf NNP cord-015369-72cjogxz 6007 7 unterschiedlicher unterschiedlicher NNP cord-015369-72cjogxz 6008 1 Höhe Höhe NNP cord-015369-72cjogxz 6008 2 des des NNP cord-015369-72cjogxz 6008 3 Armnervengeflechtes Armnervengeflechtes NNPS cord-015369-72cjogxz 6008 4 und und XX cord-015369-72cjogxz 6009 1 den den NNP cord-015369-72cjogxz 6009 2 entsprechenden entsprechenden NNP cord-015369-72cjogxz 6009 3 Armnerven Armnerven NNP cord-015369-72cjogxz 6009 4 auftreten auftreten NNP cord-015369-72cjogxz 6010 1 und und IN cord-015369-72cjogxz 6010 2 dem dem NNP cord-015369-72cjogxz 6010 3 Unerfahrenen Unerfahrenen NNP cord-015369-72cjogxz 6010 4 als als NN cord-015369-72cjogxz 6010 5 typische typische NNP cord-015369-72cjogxz 6010 6 Nervenkompressionskasuistik Nervenkompressionskasuistik NNP cord-015369-72cjogxz 6010 7 imponieren imponieren NNP cord-015369-72cjogxz 6010 8 . . . cord-015369-72cjogxz 6011 1 Bei Bei NNP cord-015369-72cjogxz 6011 2 genauer genauer NNP cord-015369-72cjogxz 6011 3 Begutachtung Begutachtung NNP cord-015369-72cjogxz 6011 4 zeigt zeigt NNP cord-015369-72cjogxz 6011 5 sich sich NNP cord-015369-72cjogxz 6012 1 jedoch jedoch NNP cord-015369-72cjogxz 6012 2 eine eine NNP cord-015369-72cjogxz 6012 3 spontan spontan NNP cord-015369-72cjogxz 6013 1 aufgetretene aufgetretene NNP cord-015369-72cjogxz 6013 2 rein rein NNP cord-015369-72cjogxz 6013 3 motorische motorische NNP cord-015369-72cjogxz 6013 4 Lähmung Lähmung NNP cord-015369-72cjogxz 6013 5 mit mit NNP cord-015369-72cjogxz 6013 6 entsprechender entsprechender NNP cord-015369-72cjogxz 6014 1 Anamnese Anamnese NNP cord-015369-72cjogxz 6014 2 und und IN cord-015369-72cjogxz 6015 1 typischen typischen NNP cord-015369-72cjogxz 6015 2 Prodroma Prodroma NNP cord-015369-72cjogxz 6015 3 . . . cord-015369-72cjogxz 6016 1 Die die VB cord-015369-72cjogxz 6017 1 Elektroneurographie Elektroneurographie NNP cord-015369-72cjogxz 6017 2 zeigt zeigt NNP cord-015369-72cjogxz 6017 3 eine eine NNP cord-015369-72cjogxz 6017 4 deutlich deutlich NNP cord-015369-72cjogxz 6017 5 erniedrigte erniedrigte NNP cord-015369-72cjogxz 6017 6 SPA SPA NNP cord-015369-72cjogxz 6017 7 mit mit NNP cord-015369-72cjogxz 6017 8 Denervationspotentialen Denervationspotentialen NNP cord-015369-72cjogxz 6017 9 als als NN cord-015369-72cjogxz 6017 10 Reflexion reflexion NN cord-015369-72cjogxz 6017 11 der der NN cord-015369-72cjogxz 6017 12 rein rein NN cord-015369-72cjogxz 6018 1 axonalen axonalen NNP cord-015369-72cjogxz 6018 2 Schädigung Schädigung NNP cord-015369-72cjogxz 6018 3 des des FW cord-015369-72cjogxz 6018 4 motorischen motorischen NNP cord-015369-72cjogxz 6018 5 Systems Systems NNP cord-015369-72cjogxz 6018 6 . . . cord-015369-72cjogxz 6019 1 In in IN cord-015369-72cjogxz 6019 2 diesem diesem JJ cord-015369-72cjogxz 6019 3 Bericht Bericht NNP cord-015369-72cjogxz 6019 4 werden werden NNP cord-015369-72cjogxz 6020 1 wir wir NNP cord-015369-72cjogxz 6020 2 die die VBP cord-015369-72cjogxz 6020 3 typische typische NNP cord-015369-72cjogxz 6020 4 Klinik Klinik NNP cord-015369-72cjogxz 6020 5 der der NNP cord-015369-72cjogxz 6020 6 häufigsten häufigsten NNP cord-015369-72cjogxz 6020 7 Neuritiden Neuritiden NNP cord-015369-72cjogxz 6020 8 der der NNP cord-015369-72cjogxz 6020 9 oberen oberen NNP cord-015369-72cjogxz 6020 10 Extremität Extremität NNP cord-015369-72cjogxz 6020 11 und und IN cord-015369-72cjogxz 6020 12 deren deren NNP cord-015369-72cjogxz 6020 13 Therapie Therapie NNP cord-015369-72cjogxz 6020 14 anhand anhand NNP cord-015369-72cjogxz 6020 15 von von NNP cord-015369-72cjogxz 6020 16 Fallbeispielen Fallbeispielen NNP cord-015369-72cjogxz 6020 17 präsentieren präsentieren NNP cord-015369-72cjogxz 6021 1 und und IN cord-015369-72cjogxz 6021 2 einen einen NNP cord-015369-72cjogxz 6021 3 diagnostischen diagnostischen NNP cord-015369-72cjogxz 6021 4 und und IN cord-015369-72cjogxz 6021 5 therapeutischen therapeutischen NNP cord-015369-72cjogxz 6021 6 Algorithmus Algorithmus NNP cord-015369-72cjogxz 6021 7 vorstellen vorstellen NNP cord-015369-72cjogxz 6021 8 . . . cord-015369-72cjogxz 6022 1 Die die VB cord-015369-72cjogxz 6022 2 zweizeitige zweizeitige NNP cord-015369-72cjogxz 6022 3 Beugesehnenrekonstruktion Beugesehnenrekonstruktion NNP cord-015369-72cjogxz 6022 4 C. C. NNP cord-015369-72cjogxz 6022 5 Pazourek Pazourek NNP cord-015369-72cjogxz 6022 6 , , , cord-015369-72cjogxz 6022 7 U. U. NNP cord-015369-72cjogxz 6022 8 Mildner Mildner NNP cord-015369-72cjogxz 6022 9 - - HYPH cord-015369-72cjogxz 6022 10 Deutschmann Deutschmann NNP cord-015369-72cjogxz 6022 11 , , , cord-015369-72cjogxz 6022 12 P. P. NNP cord-015369-72cjogxz 6022 13 Aspalter Aspalter NNP cord-015369-72cjogxz 6022 14 , , , cord-015369-72cjogxz 6022 15 A. A. NNP cord-015369-72cjogxz 6022 16 Pachucki Pachucki NNP cord-015369-72cjogxz 6022 17 LK LK NNP cord-015369-72cjogxz 6022 18 Mostviertel Mostviertel NNP cord-015369-72cjogxz 6022 19 Amstetten Amstetten NNP cord-015369-72cjogxz 6022 20 , , , cord-015369-72cjogxz 6022 21 Amstetten Amstetten NNP cord-015369-72cjogxz 6022 22 , , , cord-015369-72cjogxz 6022 23 Austria Austria NNP cord-015369-72cjogxz 6022 24 Wir Wir NNP cord-015369-72cjogxz 6022 25 zeigen zeigen NNP cord-015369-72cjogxz 6023 1 an an DT cord-015369-72cjogxz 6023 2 mehreren mehreren NNP cord-015369-72cjogxz 6023 3 Fallbeispielen Fallbeispielen NNP cord-015369-72cjogxz 6023 4 einen einen NNP cord-015369-72cjogxz 6023 5 Algorithmus Algorithmus NNP cord-015369-72cjogxz 6023 6 zur zur NNP cord-015369-72cjogxz 6023 7 Rekonstruktion Rekonstruktion NNP cord-015369-72cjogxz 6023 8 von von NNP cord-015369-72cjogxz 6023 9 Beugesehnen Beugesehnen NNP cord-015369-72cjogxz 6023 10 der der NNP cord-015369-72cjogxz 6023 11 Hand Hand NNP cord-015369-72cjogxz 6024 1 sowie sowie NNP cord-015369-72cjogxz 6024 2 deren deren NNP cord-015369-72cjogxz 6024 3 Sehnenscheiden Sehnenscheiden NNP cord-015369-72cjogxz 6024 4 und und XX cord-015369-72cjogxz 6025 1 Ringbänder Ringbänder NNP cord-015369-72cjogxz 6026 1 i -PRON- PRP cord-015369-72cjogxz 6026 2 m be VBP cord-015369-72cjogxz 6026 3 Rahmen Rahmen NNP cord-015369-72cjogxz 6026 4 eines eines NNP cord-015369-72cjogxz 6026 5 zweizeitigen zweizeitigen NNP cord-015369-72cjogxz 6026 6 Verfahrens Verfahrens NNP cord-015369-72cjogxz 6026 7 unter unter NNP cord-015369-72cjogxz 6026 8 intermittiernder intermittiernder NNP cord-015369-72cjogxz 6026 9 Verwendung Verwendung NNP cord-015369-72cjogxz 6026 10 eines eines CC cord-015369-72cjogxz 6026 11 Silastikstabes Silastikstabes NNP cord-015369-72cjogxz 6026 12 . . . cord-015369-72cjogxz 6027 1 Wir Wir NNP cord-015369-72cjogxz 6027 2 gehen gehen NNP cord-015369-72cjogxz 6027 3 auf auf NNP cord-015369-72cjogxz 6027 4 einzelne einzelne NNP cord-015369-72cjogxz 6028 1 Indikationen Indikationen NNP cord-015369-72cjogxz 6028 2 ein ein VBP cord-015369-72cjogxz 6028 3 und und IN cord-015369-72cjogxz 6028 4 entwickeln entwickeln NNP cord-015369-72cjogxz 6028 5 in in IN cord-015369-72cjogxz 6028 6 der der NNP cord-015369-72cjogxz 6028 7 Folge Folge NNP cord-015369-72cjogxz 6028 8 ein ein NNP cord-015369-72cjogxz 6028 9 Schema schema NN cord-015369-72cjogxz 6028 10 zum zum NNP cord-015369-72cjogxz 6028 11 zeitlichen zeitlichen NNP cord-015369-72cjogxz 6028 12 Ablauf Ablauf NNP cord-015369-72cjogxz 6028 13 . . . cord-015369-72cjogxz 6029 1 Die die VB cord-015369-72cjogxz 6029 2 Op Op NNP cord-015369-72cjogxz 6029 3 - - HYPH cord-015369-72cjogxz 6029 4 Technik Technik NNP cord-015369-72cjogxz 6029 5 wird wird NNP cord-015369-72cjogxz 6029 6 beschrieben beschrieben NNP cord-015369-72cjogxz 6029 7 , , , cord-015369-72cjogxz 6029 8 ebenso ebenso NNP cord-015369-72cjogxz 6029 9 wie wie NNP cord-015369-72cjogxz 6029 10 zu zu NNP cord-015369-72cjogxz 6029 11 gewährtigende gewährtigende NNP cord-015369-72cjogxz 6029 12 Komplikationen Komplikationen NNP cord-015369-72cjogxz 6029 13 . . . cord-015369-72cjogxz 6030 1 Visceral visceral JJ cord-015369-72cjogxz 6030 2 heme heme NN cord-015369-72cjogxz 6030 3 oxygenase-1 oxygenase-1 NNP cord-015369-72cjogxz 6030 4 expression expression NN cord-015369-72cjogxz 6030 5 is be VBZ cord-015369-72cjogxz 6030 6 determined determine VBN cord-015369-72cjogxz 6030 7 by by IN cord-015369-72cjogxz 6030 8 hip hip NN cord-015369-72cjogxz 6030 9 to to IN cord-015369-72cjogxz 6030 10 waist waist NN cord-015369-72cjogxz 6030 11 ratio ratio NN cord-015369-72cjogxz 6030 12 and and CC cord-015369-72cjogxz 6030 13 linked link VBN cord-015369-72cjogxz 6030 14 to to IN cord-015369-72cjogxz 6030 15 insulin insulin NN cord-015369-72cjogxz 6030 16 sensitivity sensitivity NN cord-015369-72cjogxz 6030 17 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6030 18 . . . cord-015369-72cjogxz 6031 1 Das Das NNP cord-015369-72cjogxz 6031 2 diffuse diffuse NN cord-015369-72cjogxz 6031 3 intravaskuläre intravaskuläre NNP cord-015369-72cjogxz 6031 4 B b NN cord-015369-72cjogxz 6032 1 -Zell -Zell NNP cord-015369-72cjogxz 6032 2 - - HYPH cord-015369-72cjogxz 6032 3 Lymphom Lymphom NNP cord-015369-72cjogxz 6033 1 ( ( -LRB- cord-015369-72cjogxz 6033 2 IVL IVL NNP cord-015369-72cjogxz 6033 3 ) ) -RRB- cord-015369-72cjogxz 6033 4 ist ist NNP cord-015369-72cjogxz 6033 5 eine eine NNP cord-015369-72cjogxz 6033 6 seltene seltene NNP cord-015369-72cjogxz 6033 7 , , , cord-015369-72cjogxz 6033 8 maligne maligne NNP cord-015369-72cjogxz 6033 9 Erkrankung Erkrankung NNP cord-015369-72cjogxz 6033 10 , , , cord-015369-72cjogxz 6033 11 charakterisiert charakterisiert NNP cord-015369-72cjogxz 6033 12 durch durch NNP cord-015369-72cjogxz 6033 13 eine eine NNP cord-015369-72cjogxz 6033 14 intravaskuläre intravaskuläre NNP cord-015369-72cjogxz 6033 15 Proliferation Proliferation NNP cord-015369-72cjogxz 6033 16 von von NNP cord-015369-72cjogxz 6033 17 Lymphomzellen Lymphomzellen NNP cord-015369-72cjogxz 6033 18 mit mit NNP cord-015369-72cjogxz 6033 19 konsekutiven konsekutiven NNP cord-015369-72cjogxz 6033 20 Thrombosen Thrombosen NNP cord-015369-72cjogxz 6033 21 der der NNP cord-015369-72cjogxz 6033 22 Kapillaren Kapillaren NNP cord-015369-72cjogxz 6033 23 und und IN cord-015369-72cjogxz 6033 24 kleinen kleinen NNP cord-015369-72cjogxz 6033 25 Gefässe Gefässe NNP cord-015369-72cjogxz 6033 26 mit mit NNP cord-015369-72cjogxz 6033 27 nachgeschalteten nachgeschalteten JJ cord-015369-72cjogxz 6033 28 nachgeschalteten nachgeschalteten NNP cord-015369-72cjogxz 6033 29 Organischämien Organischämien NNP cord-015369-72cjogxz 6033 30 . . . cord-015369-72cjogxz 6034 1 Jedes Jedes NNP cord-015369-72cjogxz 6035 1 Organsystem Organsystem NNP cord-015369-72cjogxz 6035 2 kann kann NNP cord-015369-72cjogxz 6035 3 davon davon NNP cord-015369-72cjogxz 6035 4 betroffen betroffen NNP cord-015369-72cjogxz 6035 5 sein sein NNP cord-015369-72cjogxz 6035 6 , , , cord-015369-72cjogxz 6035 7 die die VB cord-015369-72cjogxz 6035 8 Diagnosestellung Diagnosestellung NNP cord-015369-72cjogxz 6035 9 erfolgt erfolgt NNP cord-015369-72cjogxz 6035 10 ausschließlich ausschließlich NNP cord-015369-72cjogxz 6035 11 histologisch histologisch NN cord-015369-72cjogxz 6035 12 . . . cord-015369-72cjogxz 6036 1 Eine Eine NNP cord-015369-72cjogxz 6036 2 49 49 CD cord-015369-72cjogxz 6036 3 jährige jährige NN cord-015369-72cjogxz 6036 4 Patientin Patientin NNP cord-015369-72cjogxz 6036 5 zeigte zeigte NNP cord-015369-72cjogxz 6036 6 seit seit NNP cord-015369-72cjogxz 6036 7 drei drei NNP cord-015369-72cjogxz 6037 1 Monaten Monaten NNP cord-015369-72cjogxz 6037 2 B B NNP cord-015369-72cjogxz 6037 3 - - HYPH cord-015369-72cjogxz 6037 4 Symptomatik Symptomatik NNP cord-015369-72cjogxz 6037 5 mit mit NNP cord-015369-72cjogxz 6037 6 Fieberschüben Fieberschüben NNP cord-015369-72cjogxz 6037 7 bis bis NN cord-015369-72cjogxz 6037 8 zu zu XX cord-015369-72cjogxz 6038 1 40 40 CD cord-015369-72cjogxz 6038 2 C C NNP cord-015369-72cjogxz 6038 3 , , , cord-015369-72cjogxz 6038 4 Reizhusten Reizhusten NNP cord-015369-72cjogxz 6038 5 und und IN cord-015369-72cjogxz 6038 6 Müdigkeit Müdigkeit NNP cord-015369-72cjogxz 6038 7 . . . cord-015369-72cjogxz 6039 1 Zusätzlich Zusätzlich NNP cord-015369-72cjogxz 6039 2 lagen lagen NNP cord-015369-72cjogxz 6040 1 eine eine NNP cord-015369-72cjogxz 6040 2 Hepatosplenomegalie Hepatosplenomegalie NNP cord-015369-72cjogxz 6040 3 mit mit NNP cord-015369-72cjogxz 6040 4 Hypoperfusion Hypoperfusion NNP cord-015369-72cjogxz 6040 5 der der NNP cord-015369-72cjogxz 6040 6 Milz Milz NNP cord-015369-72cjogxz 6040 7 , , , cord-015369-72cjogxz 6040 8 erhöhte erhöhte NNP cord-015369-72cjogxz 6040 9 Entzündungsparameter Entzündungsparameter NNP cord-015369-72cjogxz 6040 10 mit mit NNP cord-015369-72cjogxz 6040 11 Anämie Anämie NNP cord-015369-72cjogxz 6040 12 , , , cord-015369-72cjogxz 6040 13 sowie sowie NNP cord-015369-72cjogxz 6040 14 eine eine NNP cord-015369-72cjogxz 6040 15 HSV HSV NNP cord-015369-72cjogxz 6040 16 - - HYPH cord-015369-72cjogxz 6040 17 Infektion Infektion NNP cord-015369-72cjogxz 6040 18 und und IN cord-015369-72cjogxz 6040 19 ein ein NN cord-015369-72cjogxz 6040 20 pulmonaler pulmonaler NN cord-015369-72cjogxz 6040 21 Hypertonus Hypertonus NNP cord-015369-72cjogxz 6040 22 vor vor NNP cord-015369-72cjogxz 6040 23 . . . cord-015369-72cjogxz 6041 1 Methodik Methodik NNP cord-015369-72cjogxz 6041 2 . . . cord-015369-72cjogxz 6042 1 I -PRON- PRP cord-015369-72cjogxz 6042 2 m be VBP cord-015369-72cjogxz 6042 3 Thorax Thorax NNP cord-015369-72cjogxz 6042 4 - - HYPH cord-015369-72cjogxz 6042 5 CT CT NNP cord-015369-72cjogxz 6042 6 wurden wurden NNS cord-015369-72cjogxz 6042 7 konfluierende konfluierende NNP cord-015369-72cjogxz 6042 8 Infiltrate Infiltrate NNP cord-015369-72cjogxz 6042 9 in in IN cord-015369-72cjogxz 6042 10 beiden beiden NNP cord-015369-72cjogxz 6042 11 Oberlappen Oberlappen NNP cord-015369-72cjogxz 6042 12 und und IN cord-015369-72cjogxz 6042 13 in in IN cord-015369-72cjogxz 6042 14 den den NNP cord-015369-72cjogxz 6042 15 apikalen apikalen NNP cord-015369-72cjogxz 6043 1 Unterlappenanteilen Unterlappenanteilen NNP cord-015369-72cjogxz 6043 2 verifiziert verifiziert NNP cord-015369-72cjogxz 6044 1 , , , cord-015369-72cjogxz 6044 2 i -PRON- PRP cord-015369-72cjogxz 6044 3 m be VBP cord-015369-72cjogxz 6044 4 PET PET NNP cord-015369-72cjogxz 6044 5 - - HYPH cord-015369-72cjogxz 6044 6 Scan scan JJ cord-015369-72cjogxz 6044 7 fand fand NN cord-015369-72cjogxz 6044 8 sich sich NNP cord-015369-72cjogxz 6044 9 kein kein NNP cord-015369-72cjogxz 6044 10 pathologischer pathologischer NNP cord-015369-72cjogxz 6044 11 FDG FDG NNP cord-015369-72cjogxz 6044 12 - - HYPH cord-015369-72cjogxz 6044 13 Uptake Uptake NNP cord-015369-72cjogxz 6044 14 . . . cord-015369-72cjogxz 6045 1 Aufgrund Aufgrund NNP cord-015369-72cjogxz 6045 2 von von NNP cord-015369-72cjogxz 6045 3 Candida Candida NNP cord-015369-72cjogxz 6045 4 albicans albican NNS cord-015369-72cjogxz 6046 1 i i PRP cord-015369-72cjogxz 6047 1 m m LS cord-015369-72cjogxz 6048 1 Tracheobronchialsekret Tracheobronchialsekret NNP cord-015369-72cjogxz 6048 2 bestand bestand NNP cord-015369-72cjogxz 6048 3 der der NNP cord-015369-72cjogxz 6048 4 Verdacht Verdacht NNP cord-015369-72cjogxz 6048 5 einer einer NNP cord-015369-72cjogxz 6048 6 pulmonalen pulmonalen NN cord-015369-72cjogxz 6048 7 Mykose Mykose NNP cord-015369-72cjogxz 6048 8 . . . cord-015369-72cjogxz 6049 1 Zur Zur NNP cord-015369-72cjogxz 6049 2 histologischen histologischen NNP cord-015369-72cjogxz 6049 3 Diagnostik Diagnostik NNP cord-015369-72cjogxz 6049 4 erfolgte erfolgte NN cord-015369-72cjogxz 6049 5 eine eine XX cord-015369-72cjogxz 6050 1 thorakoskopische thorakoskopische NNP cord-015369-72cjogxz 6050 2 Keilresektion Keilresektion NNP cord-015369-72cjogxz 6051 1 i -PRON- PRP cord-015369-72cjogxz 6051 2 m be VBP cord-015369-72cjogxz 6051 3 Segment Segment NNP cord-015369-72cjogxz 6051 4 1 1 CD cord-015369-72cjogxz 6051 5 rechts recht NNS cord-015369-72cjogxz 6051 6 . . . cord-015369-72cjogxz 6052 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6052 2 . . . cord-015369-72cjogxz 6053 1 Histologisch Histologisch NNP cord-015369-72cjogxz 6053 2 zeigte zeigte NNP cord-015369-72cjogxz 6054 1 sich sich NNP cord-015369-72cjogxz 6054 2 ein ein NNP cord-015369-72cjogxz 6054 3 diffuses diffuse VBZ cord-015369-72cjogxz 6054 4 intravaskuläres intravaskuläres NNP cord-015369-72cjogxz 6055 1 großzelliges großzelliges NNP cord-015369-72cjogxz 6055 2 B B NNP cord-015369-72cjogxz 6055 3 - - HYPH cord-015369-72cjogxz 6055 4 Zell Zell NNP cord-015369-72cjogxz 6055 5 - - HYPH cord-015369-72cjogxz 6055 6 Lymphom Lymphom NNP cord-015369-72cjogxz 6055 7 mit mit NNP cord-015369-72cjogxz 6055 8 Lambda Lambda NNP cord-015369-72cjogxz 6055 9 - - HYPH cord-015369-72cjogxz 6055 10 Positivität Positivität NNP cord-015369-72cjogxz 6055 11 , , , cord-015369-72cjogxz 6055 12 positiver positiver NNP cord-015369-72cjogxz 6055 13 immunhistochemischer immunhistochemischer NNP cord-015369-72cjogxz 6056 1 Reaktion Reaktion NNP cord-015369-72cjogxz 6056 2 auf auf NNP cord-015369-72cjogxz 6057 1 VEGFR2 VEGFR2 NNP cord-015369-72cjogxz 6058 1 und und NNP cord-015369-72cjogxz 6059 1 VEGFR3 vegfr3 XX cord-015369-72cjogxz 6059 2 , , , cord-015369-72cjogxz 6059 3 sowie sowie JJ cord-015369-72cjogxz 6059 4 CD CD NNP cord-015369-72cjogxz 6059 5 5-Koexpression 5-Koexpression NNP cord-015369-72cjogxz 6059 6 . . . cord-015369-72cjogxz 6060 1 Typischerweise Typischerweise NNP cord-015369-72cjogxz 6060 2 wiesen wiesen NNS cord-015369-72cjogxz 6060 3 die die VBP cord-015369-72cjogxz 6060 4 Arteriolen Arteriolen NNP cord-015369-72cjogxz 6060 5 , , , cord-015369-72cjogxz 6061 1 Venolen Venolen NNP cord-015369-72cjogxz 6061 2 und und IN cord-015369-72cjogxz 6061 3 kleinen kleinen NNP cord-015369-72cjogxz 6061 4 peripheren peripheren NNP cord-015369-72cjogxz 6062 1 Gefässe Gefässe NNP cord-015369-72cjogxz 6062 2 eine eine JJ cord-015369-72cjogxz 6062 3 vollständige vollständige NN cord-015369-72cjogxz 6063 1 Thrombosierung Thrombosierung NNP cord-015369-72cjogxz 6063 2 durch durch NNP cord-015369-72cjogxz 6063 3 Tumorzellen Tumorzellen NNP cord-015369-72cjogxz 6063 4 auf auf NNP cord-015369-72cjogxz 6063 5 . . . cord-015369-72cjogxz 6064 1 Die die VB cord-015369-72cjogxz 6064 2 Patientin Patientin NNP cord-015369-72cjogxz 6064 3 entwickelte entwickelte NNP cord-015369-72cjogxz 6064 4 peri peri JJ cord-015369-72cjogxz 6064 5 - - HYPH cord-015369-72cjogxz 6064 6 operativ operativ JJ cord-015369-72cjogxz 6064 7 ein ein FW cord-015369-72cjogxz 6064 8 SIRS SIRS NNP cord-015369-72cjogxz 6064 9 - - HYPH cord-015369-72cjogxz 6064 10 artiges artige NNS cord-015369-72cjogxz 6064 11 Bild Bild NNP cord-015369-72cjogxz 6064 12 mit mit NNP cord-015369-72cjogxz 6064 13 nicht nicht NNP cord-015369-72cjogxz 6064 14 beherrschbarer beherrschbarer NNP cord-015369-72cjogxz 6064 15 Sepsis Sepsis NNP cord-015369-72cjogxz 6064 16 , , , cord-015369-72cjogxz 6064 17 welche welche NNP cord-015369-72cjogxz 6064 18 den den NNP cord-015369-72cjogxz 6064 19 sofortigen sofortigen NNP cord-015369-72cjogxz 6064 20 Beginn Beginn NNP cord-015369-72cjogxz 6065 1 einer einer NNP cord-015369-72cjogxz 6065 2 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 6065 3 nicht nicht NNP cord-015369-72cjogxz 6065 4 zuließ zuließ NNP cord-015369-72cjogxz 6065 5 . . . cord-015369-72cjogxz 6066 1 Sie Sie NNP cord-015369-72cjogxz 6066 2 verstarb verstarb NNP cord-015369-72cjogxz 6066 3 am be VBP cord-015369-72cjogxz 6066 4 9 9 CD cord-015369-72cjogxz 6066 5 . . . cord-015369-72cjogxz 6067 1 postoperativen postoperativen NNP cord-015369-72cjogxz 6068 1 Tag tag VB cord-015369-72cjogxz 6068 2 an an DT cord-015369-72cjogxz 6068 3 den den JJ cord-015369-72cjogxz 6068 4 Folgen Folgen NNP cord-015369-72cjogxz 6068 5 des des NNP cord-015369-72cjogxz 6068 6 Multiorganversagens Multiorganversagens NNP cord-015369-72cjogxz 6068 7 . . . cord-015369-72cjogxz 6069 1 In in IN cord-015369-72cjogxz 6069 2 der der NNP cord-015369-72cjogxz 6069 3 Obduktion Obduktion NNP cord-015369-72cjogxz 6069 4 fanden fanden NNP cord-015369-72cjogxz 6069 5 sich sich NNP cord-015369-72cjogxz 6069 6 als als NNP cord-015369-72cjogxz 6069 7 Ursache Ursache NNP cord-015369-72cjogxz 6069 8 des des NNP cord-015369-72cjogxz 6069 9 MOV MOV NNP cord-015369-72cjogxz 6069 10 Tumorzellembolien Tumorzellembolien NNP cord-015369-72cjogxz 6069 11 in in IN cord-015369-72cjogxz 6069 12 allen allen NNP cord-015369-72cjogxz 6069 13 parenchymatösen parenchymatösen NNP cord-015369-72cjogxz 6069 14 Organen Organen NNP cord-015369-72cjogxz 6069 15 . . . cord-015369-72cjogxz 6070 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6070 2 . . . cord-015369-72cjogxz 6071 1 Das Das NNP cord-015369-72cjogxz 6071 2 diffuse diffuse NN cord-015369-72cjogxz 6071 3 intravaskuläre intravaskuläre NNP cord-015369-72cjogxz 6071 4 B b NN cord-015369-72cjogxz 6072 1 -Zell -Zell NNP cord-015369-72cjogxz 6072 2 Lymphom Lymphom NNP cord-015369-72cjogxz 6072 3 zeigt zeigt NNP cord-015369-72cjogxz 6073 1 i -PRON- PRP cord-015369-72cjogxz 6073 2 m be VBP cord-015369-72cjogxz 6073 3 Vergleich Vergleich NNP cord-015369-72cjogxz 6073 4 zur zur NNP cord-015369-72cjogxz 6073 5 kutanen kutanen NNP cord-015369-72cjogxz 6073 6 Manifestationsform Manifestationsform NNP cord-015369-72cjogxz 6074 1 eine eine NNP cord-015369-72cjogxz 6074 2 extrem extrem JJ cord-015369-72cjogxz 6074 3 ungünstige ungünstige NNP cord-015369-72cjogxz 6074 4 Prognose Prognose NNP cord-015369-72cjogxz 6074 5 . . . cord-015369-72cjogxz 6075 1 Das Das NNP cord-015369-72cjogxz 6075 2 Ü Ü NNP cord-015369-72cjogxz 6076 1 berleben berleben NNP cord-015369-72cjogxz 6076 2 ist ist NNP cord-015369-72cjogxz 6077 1 wesentlich wesentlich NNP cord-015369-72cjogxz 6078 1 von von NNP cord-015369-72cjogxz 6078 2 der der NNP cord-015369-72cjogxz 6079 1 frühzeitigen frühzeitigen NNP cord-015369-72cjogxz 6079 2 Diagnose diagnose VBP cord-015369-72cjogxz 6079 3 und und IN cord-015369-72cjogxz 6079 4 dem dem NNP cord-015369-72cjogxz 6079 5 sofortigen sofortigen NNP cord-015369-72cjogxz 6079 6 Therapiebeginn Therapiebeginn NNP cord-015369-72cjogxz 6079 7 abhängig abhängig NNS cord-015369-72cjogxz 6079 8 . . . cord-015369-72cjogxz 6080 1 Bei Bei NNP cord-015369-72cjogxz 6080 2 ischämischen ischämischen NNP cord-015369-72cjogxz 6080 3 Organläsionen Organläsionen NNP cord-015369-72cjogxz 6080 4 in in IN cord-015369-72cjogxz 6080 5 Verbindung Verbindung NNP cord-015369-72cjogxz 6080 6 mit mit NNP cord-015369-72cjogxz 6080 7 Fieber Fieber NNP cord-015369-72cjogxz 6080 8 sollte sollte NNP cord-015369-72cjogxz 6080 9 daher daher NNP cord-015369-72cjogxz 6080 10 immer immer NNP cord-015369-72cjogxz 6081 1 an an DT cord-015369-72cjogxz 6081 2 das das NNP cord-015369-72cjogxz 6081 3 Vorliegen Vorliegen NNP cord-015369-72cjogxz 6081 4 eines eines NNPS cord-015369-72cjogxz 6081 5 intravaskulären intravaskulären NNP cord-015369-72cjogxz 6081 6 Lymphoms Lymphoms NNP cord-015369-72cjogxz 6081 7 gedacht gedacht NNP cord-015369-72cjogxz 6081 8 werden werden NNP cord-015369-72cjogxz 6081 9 . . . cord-015369-72cjogxz 6082 1 Die Die NNP cord-015369-72cjogxz 6082 2 Auswirkung Auswirkung NNP cord-015369-72cjogxz 6082 3 von von NNP cord-015369-72cjogxz 6082 4 präoperativem präoperativem NNP cord-015369-72cjogxz 6083 1 Aufwärmen Aufwärmen NNP cord-015369-72cjogxz 6083 2 auf auf NNP cord-015369-72cjogxz 6084 1 die die VB cord-015369-72cjogxz 6085 1 Performance performance NN cord-015369-72cjogxz 6085 2 von von NNP cord-015369-72cjogxz 6085 3 unerfahrenen unerfahrenen NNP cord-015369-72cjogxz 6086 1 und und IN cord-015369-72cjogxz 6086 2 erfahrenen erfahrenen NNP cord-015369-72cjogxz 6086 3 Chirurgen Chirurgen NNP cord-015369-72cjogxz 6086 4 bei bei NNP cord-015369-72cjogxz 6086 5 der der NNP cord-015369-72cjogxz 6086 6 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 6086 7 Cholezystektomie Cholezystektomie NNP cord-015369-72cjogxz 6086 8 Das Das NNP cord-015369-72cjogxz 6086 9 Aufwärmen Aufwärmen NNP cord-015369-72cjogxz 6087 1 vor vor NNP cord-015369-72cjogxz 6087 2 der der NNP cord-015369-72cjogxz 6087 3 eigentlichen eigentlichen NN cord-015369-72cjogxz 6087 4 Tätigkeit Tätigkeit NNP cord-015369-72cjogxz 6087 5 gehört gehört NNP cord-015369-72cjogxz 6087 6 in in IN cord-015369-72cjogxz 6087 7 vielen vielen NNP cord-015369-72cjogxz 6087 8 Bereichen Bereichen NNP cord-015369-72cjogxz 6087 9 , , , cord-015369-72cjogxz 6087 10 etwa etwa NNP cord-015369-72cjogxz 6087 11 dem dem NNP cord-015369-72cjogxz 6087 12 Spitzensport Spitzensport NNP cord-015369-72cjogxz 6087 13 oder oder NNP cord-015369-72cjogxz 6087 14 der der NNP cord-015369-72cjogxz 6087 15 Fliegerei Fliegerei NNP cord-015369-72cjogxz 6087 16 , , , cord-015369-72cjogxz 6087 17 zur zur NNP cord-015369-72cjogxz 6087 18 täglichen täglichen NNP cord-015369-72cjogxz 6087 19 Routine Routine NNP cord-015369-72cjogxz 6087 20 . . . cord-015369-72cjogxz 6088 1 Wir Wir NNP cord-015369-72cjogxz 6088 2 haben haben NNP cord-015369-72cjogxz 6088 3 die die VBP cord-015369-72cjogxz 6088 4 Auswirkung Auswirkung NNP cord-015369-72cjogxz 6088 5 von von NNP cord-015369-72cjogxz 6088 6 präoperativem präoperativem NN cord-015369-72cjogxz 6088 7 Aufwärmen Aufwärmen NNP cord-015369-72cjogxz 6088 8 an an DT cord-015369-72cjogxz 6088 9 einem einem NNP cord-015369-72cjogxz 6088 10 Laparoskopie Laparoskopie NNP cord-015369-72cjogxz 6089 1 -Simulator -Simulator : cord-015369-72cjogxz 6089 2 auf auf NNP cord-015369-72cjogxz 6089 3 die die VBP cord-015369-72cjogxz 6090 1 Operationsergebnisse Operationsergebnisse NNP cord-015369-72cjogxz 6090 2 bei bei NNP cord-015369-72cjogxz 6090 3 einer einer NNP cord-015369-72cjogxz 6090 4 laparoskopischen laparoskopischen NNP cord-015369-72cjogxz 6090 5 Cholezystektomie Cholezystektomie NNP cord-015369-72cjogxz 6090 6 , , , cord-015369-72cjogxz 6090 7 sowohl sowohl NNP cord-015369-72cjogxz 6090 8 fü fü IN cord-015369-72cjogxz 6090 9 r r NNP cord-015369-72cjogxz 6090 10 junge junge NNP cord-015369-72cjogxz 6090 11 als als NN cord-015369-72cjogxz 6091 1 auch auch NNP cord-015369-72cjogxz 6091 2 erfahrene erfahrene NNP cord-015369-72cjogxz 6091 3 Chirurgen Chirurgen NNP cord-015369-72cjogxz 6091 4 , , , cord-015369-72cjogxz 6091 5 untersucht untersucht NNP cord-015369-72cjogxz 6091 6 . . . cord-015369-72cjogxz 6092 1 6 6 CD cord-015369-72cjogxz 6092 2 Chirurgen Chirurgen NNP cord-015369-72cjogxz 6092 3 ( ( -LRB- cord-015369-72cjogxz 6092 4 3 3 CD cord-015369-72cjogxz 6092 5 mit mit NNP cord-015369-72cjogxz 6092 6 über über NNP cord-015369-72cjogxz 6092 7 10 10 CD cord-015369-72cjogxz 6092 8 jähriger jähriger NN cord-015369-72cjogxz 6092 9 Dienstzeit Dienstzeit NNP cord-015369-72cjogxz 6092 10 , , , cord-015369-72cjogxz 6092 11 3 3 CD cord-015369-72cjogxz 6092 12 am be VBP cord-015369-72cjogxz 6092 13 Beginn Beginn NNP cord-015369-72cjogxz 6092 14 ihrer ihrer JJ cord-015369-72cjogxz 6092 15 Ausbildung Ausbildung NNP cord-015369-72cjogxz 6092 16 ) ) -RRB- cord-015369-72cjogxz 6093 1 führten führten NNP cord-015369-72cjogxz 6093 2 jeweils jeweils NNP cord-015369-72cjogxz 6094 1 2 2 LS cord-015369-72cjogxz 6094 2 Cholezystektomien Cholezystektomien NNP cord-015369-72cjogxz 6094 3 an an DT cord-015369-72cjogxz 6094 4 einem einem JJ cord-015369-72cjogxz 6094 5 Tübinger Tübinger NNP cord-015369-72cjogxz 6094 6 Boxtrainer Boxtrainer NNP cord-015369-72cjogxz 6094 7 , , , cord-015369-72cjogxz 6094 8 mit mit NNP cord-015369-72cjogxz 6094 9 beziehungsweise beziehungsweise NNP cord-015369-72cjogxz 6094 10 ohne ohne NNP cord-015369-72cjogxz 6094 11 15 15 CD cord-015369-72cjogxz 6094 12 Minütigen Minütigen NNP cord-015369-72cjogxz 6094 13 präoperativem präoperativem NNP cord-015369-72cjogxz 6094 14 Aufwärmen Aufwärmen NNP cord-015369-72cjogxz 6095 1 an an DT cord-015369-72cjogxz 6095 2 einem einem NNP cord-015369-72cjogxz 6095 3 Laparoskopie Laparoskopie NNP cord-015369-72cjogxz 6096 1 -Simulator -Simulator : cord-015369-72cjogxz 6097 1 ( ( -LRB- cord-015369-72cjogxz 6097 2 LapSim LapSim NNP cord-015369-72cjogxz 6097 3 , , , cord-015369-72cjogxz 6097 4 Surgical Surgical NNP cord-015369-72cjogxz 6097 5 Science Science NNP cord-015369-72cjogxz 6097 6 ) ) -RRB- cord-015369-72cjogxz 6097 7 , , , cord-015369-72cjogxz 6097 8 durch durch NNP cord-015369-72cjogxz 6097 9 . . . cord-015369-72cjogxz 6098 1 In in IN cord-015369-72cjogxz 6098 2 das das NNP cord-015369-72cjogxz 6098 3 Ergebnis Ergebnis NNP cord-015369-72cjogxz 6098 4 flossen flossen NNP cord-015369-72cjogxz 6098 5 die die VBP cord-015369-72cjogxz 6098 6 Operationszeit Operationszeit NNP cord-015369-72cjogxz 6098 7 , , , cord-015369-72cjogxz 6098 8 die die VB cord-015369-72cjogxz 6098 9 Anzahl Anzahl NNP cord-015369-72cjogxz 6098 10 der der NNP cord-015369-72cjogxz 6098 11 Instrumentenwechsel Instrumentenwechsel NNP cord-015369-72cjogxz 6098 12 , , , cord-015369-72cjogxz 6098 13 die die VBP cord-015369-72cjogxz 6098 14 der der NNP cord-015369-72cjogxz 6098 15 Leberschäden Leberschäden NNP cord-015369-72cjogxz 6098 16 und und IN cord-015369-72cjogxz 6098 17 jene jene NNP cord-015369-72cjogxz 6098 18 der der NNP cord-015369-72cjogxz 6098 19 Gallelecks Gallelecks NNP cord-015369-72cjogxz 6098 20 ein ein NNP cord-015369-72cjogxz 6098 21 . . . cord-015369-72cjogxz 6099 1 Es Es NNP cord-015369-72cjogxz 6099 2 zeigte zeigte NNP cord-015369-72cjogxz 6099 3 sich sich NNP cord-015369-72cjogxz 6099 4 , , , cord-015369-72cjogxz 6099 5 dass dass NNP cord-015369-72cjogxz 6099 6 die die VBP cord-015369-72cjogxz 6099 7 jungen jungen NNP cord-015369-72cjogxz 6099 8 Chirurgen Chirurgen NNP cord-015369-72cjogxz 6099 9 bei bei NNP cord-015369-72cjogxz 6099 10 allen allen NNP cord-015369-72cjogxz 6099 11 Parametern Parametern NNP cord-015369-72cjogxz 6099 12 , , , cord-015369-72cjogxz 6100 1 bis bis NNP cord-015369-72cjogxz 6100 2 auf auf NNP cord-015369-72cjogxz 6100 3 die die VBP cord-015369-72cjogxz 6101 1 Anzahl Anzahl NNP cord-015369-72cjogxz 6101 2 der der NNP cord-015369-72cjogxz 6101 3 Instrumentenwechsel Instrumentenwechsel NNP cord-015369-72cjogxz 6101 4 von von NNP cord-015369-72cjogxz 6101 5 präoperativem präoperativem NNP cord-015369-72cjogxz 6102 1 Aufwärmen Aufwärmen NNP cord-015369-72cjogxz 6102 2 profitierten profitierten NNP cord-015369-72cjogxz 6102 3 . . . cord-015369-72cjogxz 6103 1 Bei Bei NNP cord-015369-72cjogxz 6103 2 den den NNP cord-015369-72cjogxz 6103 3 erfahrenen erfahrenen NNP cord-015369-72cjogxz 6103 4 Chirurgen Chirurgen NNP cord-015369-72cjogxz 6103 5 hingegen hingegen NNP cord-015369-72cjogxz 6103 6 zeigte zeigte NNP cord-015369-72cjogxz 6103 7 sich sich NNP cord-015369-72cjogxz 6104 1 ein ein NNP cord-015369-72cjogxz 6104 2 anderes anderes NNP cord-015369-72cjogxz 6104 3 Bild Bild NNP cord-015369-72cjogxz 6104 4 : : : cord-015369-72cjogxz 6104 5 Sie Sie NNP cord-015369-72cjogxz 6104 6 benötigten benötigten NNP cord-015369-72cjogxz 6104 7 zwar zwar NNP cord-015369-72cjogxz 6104 8 in in IN cord-015369-72cjogxz 6104 9 beiden beiden JJ cord-015369-72cjogxz 6104 10 Gruppen Gruppen NNP cord-015369-72cjogxz 6104 11 gleich gleich NNP cord-015369-72cjogxz 6104 12 lang lang NNP cord-015369-72cjogxz 6105 1 , , , cord-015369-72cjogxz 6105 2 wechselten wechselten NNP cord-015369-72cjogxz 6105 3 die die VBP cord-015369-72cjogxz 6106 1 Instrumente Instrumente NNP cord-015369-72cjogxz 6106 2 gleich gleich NNP cord-015369-72cjogxz 6107 1 oft oft NNP cord-015369-72cjogxz 6107 2 und und IN cord-015369-72cjogxz 6107 3 es es NNP cord-015369-72cjogxz 6107 4 kam kam NNP cord-015369-72cjogxz 6107 5 zu zu NNP cord-015369-72cjogxz 6107 6 gleich gleich NNP cord-015369-72cjogxz 6107 7 vielen vielen NNP cord-015369-72cjogxz 6107 8 Leberschäden Leberschäden NNP cord-015369-72cjogxz 6107 9 , , , cord-015369-72cjogxz 6107 10 allerdings allerdings NNP cord-015369-72cjogxz 6107 11 kam kam NNP cord-015369-72cjogxz 6107 12 es es NNP cord-015369-72cjogxz 6107 13 in in IN cord-015369-72cjogxz 6107 14 der der NNP cord-015369-72cjogxz 6107 15 Gruppe Gruppe NNP cord-015369-72cjogxz 6107 16 mit mit NNP cord-015369-72cjogxz 6107 17 präoperativem präoperativem NNP cord-015369-72cjogxz 6108 1 Aufwärmen Aufwärmen NNP cord-015369-72cjogxz 6108 2 zu zu NNP cord-015369-72cjogxz 6108 3 mehr mehr NNP cord-015369-72cjogxz 6108 4 Gallelecks Gallelecks NNPS cord-015369-72cjogxz 6108 5 . . . cord-015369-72cjogxz 6109 1 Präoperatives Präoperatives NNP cord-015369-72cjogxz 6109 2 Aufwärmen Aufwärmen NNP cord-015369-72cjogxz 6109 3 scheint scheint NNP cord-015369-72cjogxz 6109 4 einen einen JJ cord-015369-72cjogxz 6109 5 positiven positiven JJ cord-015369-72cjogxz 6109 6 Einfluss Einfluss NNP cord-015369-72cjogxz 6109 7 auf auf NNS cord-015369-72cjogxz 6109 8 die die JJ cord-015369-72cjogxz 6110 1 Operationsperfomance operationsperfomance NN cord-015369-72cjogxz 6110 2 von von NNP cord-015369-72cjogxz 6110 3 jungen jungen NNP cord-015369-72cjogxz 6110 4 Chirurgen Chirurgen NNP cord-015369-72cjogxz 6110 5 zu zu NNP cord-015369-72cjogxz 6110 6 haben haben NNP cord-015369-72cjogxz 6110 7 . . . cord-015369-72cjogxz 6111 1 Sie Sie NNP cord-015369-72cjogxz 6111 2 profitieren profitieren NNP cord-015369-72cjogxz 6111 3 in in IN cord-015369-72cjogxz 6111 4 Hinblick Hinblick NNP cord-015369-72cjogxz 6111 5 auf auf NNP cord-015369-72cjogxz 6111 6 die die VBP cord-015369-72cjogxz 6111 7 Operationszeit Operationszeit NNP cord-015369-72cjogxz 6111 8 , , , cord-015369-72cjogxz 6111 9 die die VBP cord-015369-72cjogxz 6111 10 Anzahl Anzahl NNP cord-015369-72cjogxz 6111 11 von von NNP cord-015369-72cjogxz 6111 12 Gallelecks Gallelecks NNP cord-015369-72cjogxz 6111 13 und und IN cord-015369-72cjogxz 6111 14 Leberschäden Leberschäden NNP cord-015369-72cjogxz 6111 15 . . . cord-015369-72cjogxz 6112 1 Erfahrene Erfahrene NNP cord-015369-72cjogxz 6112 2 Chirurgen Chirurgen NNP cord-015369-72cjogxz 6112 3 hingegen hingegen NNP cord-015369-72cjogxz 6112 4 scheinen scheinen NNP cord-015369-72cjogxz 6112 5 von von NNP cord-015369-72cjogxz 6112 6 präoperativem präoperativem NNP cord-015369-72cjogxz 6113 1 Aufwärmen Aufwärmen NNP cord-015369-72cjogxz 6113 2 nicht nicht NNP cord-015369-72cjogxz 6113 3 zu zu NNP cord-015369-72cjogxz 6113 4 profitieren profitieren NNP cord-015369-72cjogxz 6113 5 . . . cord-015369-72cjogxz 6114 1 Quality quality NN cord-015369-72cjogxz 6114 2 of of IN cord-015369-72cjogxz 6114 3 life life NN cord-015369-72cjogxz 6114 4 after after IN cord-015369-72cjogxz 6114 5 sympathetic sympathetic JJ cord-015369-72cjogxz 6114 6 block block NN cord-015369-72cjogxz 6114 7 at at IN cord-015369-72cjogxz 6114 8 T3 T3 NNP cord-015369-72cjogxz 6114 9 for for IN cord-015369-72cjogxz 6114 10 facial facial JJ cord-015369-72cjogxz 6114 11 hyperhidrosis hyperhidrosis NN cord-015369-72cjogxz 6114 12 : : : cord-015369-72cjogxz 6114 13 results result NNS cord-015369-72cjogxz 6114 14 of of IN cord-015369-72cjogxz 6114 15 a a DT cord-015369-72cjogxz 6114 16 disease disease NN cord-015369-72cjogxz 6114 17 - - HYPH cord-015369-72cjogxz 6114 18 specific specific JJ cord-015369-72cjogxz 6114 19 evaluation evaluation NN cord-015369-72cjogxz 6114 20 Background background NN cord-015369-72cjogxz 6114 21 . . . cord-015369-72cjogxz 6115 1 Endoscopic endoscopic JJ cord-015369-72cjogxz 6115 2 thoracic thoracic JJ cord-015369-72cjogxz 6115 3 sympathectomy sympathectomy NN cord-015369-72cjogxz 6115 4 at at IN cord-015369-72cjogxz 6115 5 the the DT cord-015369-72cjogxz 6115 6 2nd 2nd JJ cord-015369-72cjogxz 6115 7 thoracic thoracic JJ cord-015369-72cjogxz 6115 8 ganglion ganglion NN cord-015369-72cjogxz 6115 9 ( ( -LRB- cord-015369-72cjogxz 6115 10 T2 T2 NNP cord-015369-72cjogxz 6115 11 ) ) -RRB- cord-015369-72cjogxz 6115 12 is be VBZ cord-015369-72cjogxz 6115 13 the the DT cord-015369-72cjogxz 6115 14 treatment treatment NN cord-015369-72cjogxz 6115 15 of of IN cord-015369-72cjogxz 6115 16 choice choice NN cord-015369-72cjogxz 6115 17 for for IN cord-015369-72cjogxz 6115 18 patients patient NNS cord-015369-72cjogxz 6115 19 with with IN cord-015369-72cjogxz 6115 20 erythrophobia erythrophobia NN cord-015369-72cjogxz 6115 21 according accord VBG cord-015369-72cjogxz 6115 22 to to IN cord-015369-72cjogxz 6115 23 the the DT cord-015369-72cjogxz 6115 24 Lin Lin NNP cord-015369-72cjogxz 6115 25 Telaranta Telaranta NNP cord-015369-72cjogxz 6115 26 classification classification NN cord-015369-72cjogxz 6115 27 . . . cord-015369-72cjogxz 6116 1 Unfortunately unfortunately RB cord-015369-72cjogxz 6116 2 , , , cord-015369-72cjogxz 6116 3 the the DT cord-015369-72cjogxz 6116 4 incidence incidence NN cord-015369-72cjogxz 6116 5 of of IN cord-015369-72cjogxz 6116 6 compensatory compensatory JJ cord-015369-72cjogxz 6116 7 sweating sweating NN cord-015369-72cjogxz 6116 8 ( ( -LRB- cord-015369-72cjogxz 6116 9 CS CS NNP cord-015369-72cjogxz 6116 10 ) ) -RRB- cord-015369-72cjogxz 6116 11 was be VBD cord-015369-72cjogxz 6116 12 reported report VBN cord-015369-72cjogxz 6116 13 to to TO cord-015369-72cjogxz 6116 14 be be VB cord-015369-72cjogxz 6116 15 higher high JJR cord-015369-72cjogxz 6116 16 in in IN cord-015369-72cjogxz 6116 17 case case NN cord-015369-72cjogxz 6116 18 of of IN cord-015369-72cjogxz 6116 19 T2 T2 NNP cord-015369-72cjogxz 6116 20 sympathectomy sympathectomy NN cord-015369-72cjogxz 6116 21 . . . cord-015369-72cjogxz 6117 1 Therefore therefore RB cord-015369-72cjogxz 6117 2 , , , cord-015369-72cjogxz 6117 3 clip clip NN cord-015369-72cjogxz 6117 4 application application NN cord-015369-72cjogxz 6117 5 ( ( -LRB- cord-015369-72cjogxz 6117 6 endoscopic endoscopic JJ cord-015369-72cjogxz 6117 7 sympathetic sympathetic JJ cord-015369-72cjogxz 6117 8 block block NN cord-015369-72cjogxz 6117 9 , , , cord-015369-72cjogxz 6117 10 ESB ESB NNP cord-015369-72cjogxz 6117 11 ) ) -RRB- cord-015369-72cjogxz 6117 12 has have VBZ cord-015369-72cjogxz 6117 13 been be VBN cord-015369-72cjogxz 6117 14 introduced introduce VBN cord-015369-72cjogxz 6117 15 as as IN cord-015369-72cjogxz 6117 16 it -PRON- PRP cord-015369-72cjogxz 6117 17 provides provide VBZ cord-015369-72cjogxz 6117 18 potential potential JJ cord-015369-72cjogxz 6117 19 reversibility reversibility NN cord-015369-72cjogxz 6117 20 . . . cord-015369-72cjogxz 6118 1 The the DT cord-015369-72cjogxz 6118 2 aim aim NN cord-015369-72cjogxz 6118 3 of of IN cord-015369-72cjogxz 6118 4 the the DT cord-015369-72cjogxz 6118 5 study study NN cord-015369-72cjogxz 6118 6 was be VBD cord-015369-72cjogxz 6118 7 to to TO cord-015369-72cjogxz 6118 8 analyze analyze VB cord-015369-72cjogxz 6118 9 the the DT cord-015369-72cjogxz 6118 10 outcome outcome NN cord-015369-72cjogxz 6118 11 of of IN cord-015369-72cjogxz 6118 12 patients patient NNS cord-015369-72cjogxz 6118 13 treated treat VBN cord-015369-72cjogxz 6118 14 by by IN cord-015369-72cjogxz 6118 15 ESB ESB NNP cord-015369-72cjogxz 6118 16 at at IN cord-015369-72cjogxz 6118 17 T2 T2 NNP cord-015369-72cjogxz 6118 18 with with IN cord-015369-72cjogxz 6118 19 special special JJ cord-015369-72cjogxz 6118 20 emphasis emphasis NN cord-015369-72cjogxz 6118 21 on on IN cord-015369-72cjogxz 6118 22 the the DT cord-015369-72cjogxz 6118 23 severity severity NN cord-015369-72cjogxz 6118 24 of of IN cord-015369-72cjogxz 6118 25 CS CS NNP cord-015369-72cjogxz 6118 26 . . . cord-015369-72cjogxz 6118 27 Methods method NNS cord-015369-72cjogxz 6118 28 . . . cord-015369-72cjogxz 6119 1 Between between IN cord-015369-72cjogxz 6119 2 2002 2002 CD cord-015369-72cjogxz 6119 3 and and CC cord-015369-72cjogxz 6119 4 2009 2009 CD cord-015369-72cjogxz 6119 5 47 47 CD cord-015369-72cjogxz 6119 6 patients patient NNS cord-015369-72cjogxz 6119 7 ( ( -LRB- cord-015369-72cjogxz 6119 8 mean mean VB cord-015369-72cjogxz 6119 9 age age NN cord-015369-72cjogxz 6119 10 37 37 CD cord-015369-72cjogxz 6119 11 AE AE NNP cord-015369-72cjogxz 6119 12 11 11 CD cord-015369-72cjogxz 6119 13 years year NNS cord-015369-72cjogxz 6119 14 ) ) -RRB- cord-015369-72cjogxz 6119 15 prospectively prospectively RB cord-015369-72cjogxz 6119 16 underwent undergo VBD cord-015369-72cjogxz 6119 17 94 94 CD cord-015369-72cjogxz 6119 18 procedures procedure NNS cord-015369-72cjogxz 6119 19 . . . cord-015369-72cjogxz 6120 1 Satisfaction satisfaction NN cord-015369-72cjogxz 6120 2 rates rate NNS cord-015369-72cjogxz 6120 3 and and CC cord-015369-72cjogxz 6120 4 visual visual JJ cord-015369-72cjogxz 6120 5 analogue analogue NN cord-015369-72cjogxz 6120 6 scales scale NNS cord-015369-72cjogxz 6120 7 ( ( -LRB- cord-015369-72cjogxz 6120 8 VAS VAS NNP cord-015369-72cjogxz 6120 9 ) ) -RRB- cord-015369-72cjogxz 6120 10 from from IN cord-015369-72cjogxz 6120 11 0 0 LS cord-015369-72cjogxz 6120 12 ( ( -LRB- cord-015369-72cjogxz 6120 13 no no DT cord-015369-72cjogxz 6120 14 symptoms symptom NNS cord-015369-72cjogxz 6120 15 ) ) -RRB- cord-015369-72cjogxz 6120 16 to to IN cord-015369-72cjogxz 6120 17 10 10 CD cord-015369-72cjogxz 6120 18 ( ( -LRB- cord-015369-72cjogxz 6120 19 maximal maximal JJ cord-015369-72cjogxz 6120 20 symptoms symptom NNS cord-015369-72cjogxz 6120 21 ) ) -RRB- cord-015369-72cjogxz 6120 22 have have VBP cord-015369-72cjogxz 6120 23 been be VBN cord-015369-72cjogxz 6120 24 evaluated evaluate VBN cord-015369-72cjogxz 6120 25 . . . cord-015369-72cjogxz 6121 1 Mean mean VB cord-015369-72cjogxz 6121 2 follow follow VB cord-015369-72cjogxz 6121 3 up up RP cord-015369-72cjogxz 6121 4 was be VBD cord-015369-72cjogxz 6121 5 62.7 62.7 CD cord-015369-72cjogxz 6121 6 AE AE NNP cord-015369-72cjogxz 6121 7 12.7 12.7 CD cord-015369-72cjogxz 6121 8 months month NNS cord-015369-72cjogxz 6121 9 obtainable obtainable JJ cord-015369-72cjogxz 6121 10 from from IN cord-015369-72cjogxz 6121 11 all all DT cord-015369-72cjogxz 6121 12 patients patient NNS cord-015369-72cjogxz 6121 13 . . . cord-015369-72cjogxz 6122 1 Results result NNS cord-015369-72cjogxz 6122 2 . . . cord-015369-72cjogxz 6123 1 The the DT cord-015369-72cjogxz 6123 2 preoperative preoperative JJ cord-015369-72cjogxz 6123 3 VAS vas NN cord-015369-72cjogxz 6123 4 scores score NNS cord-015369-72cjogxz 6123 5 ameliorated ameliorate VBD cord-015369-72cjogxz 6123 6 from from IN cord-015369-72cjogxz 6123 7 8.9 8.9 CD cord-015369-72cjogxz 6123 8 AE AE NNP cord-015369-72cjogxz 6123 9 1.5 1.5 CD cord-015369-72cjogxz 6123 10 to to IN cord-015369-72cjogxz 6123 11 1.7 1.7 CD cord-015369-72cjogxz 6123 12 AE AE NNP cord-015369-72cjogxz 6123 13 0.4 0.4 CD cord-015369-72cjogxz 6123 14 six six CD cord-015369-72cjogxz 6123 15 weeks week NNS cord-015369-72cjogxz 6123 16 after after IN cord-015369-72cjogxz 6123 17 operation operation NN cord-015369-72cjogxz 6123 18 and and CC cord-015369-72cjogxz 6123 19 remained remain VBD cord-015369-72cjogxz 6123 20 stable stable JJ cord-015369-72cjogxz 6123 21 during during IN cord-015369-72cjogxz 6123 22 follow follow NN cord-015369-72cjogxz 6123 23 up up RP cord-015369-72cjogxz 6123 24 ( ( -LRB- cord-015369-72cjogxz 6123 25 p p NN cord-015369-72cjogxz 6123 26 < < XX cord-015369-72cjogxz 6123 27 0.01 0.01 CD cord-015369-72cjogxz 6123 28 ) ) -RRB- cord-015369-72cjogxz 6123 29 . . . cord-015369-72cjogxz 6124 1 37 37 CD cord-015369-72cjogxz 6124 2 patients patient NNS cord-015369-72cjogxz 6124 3 ( ( -LRB- cord-015369-72cjogxz 6124 4 78.7 78.7 CD cord-015369-72cjogxz 6124 5 % % NN cord-015369-72cjogxz 6124 6 ) ) -RRB- cord-015369-72cjogxz 6124 7 were be VBD cord-015369-72cjogxz 6124 8 free free JJ cord-015369-72cjogxz 6124 9 of of IN cord-015369-72cjogxz 6124 10 symptoms symptom NNS cord-015369-72cjogxz 6124 11 , , , cord-015369-72cjogxz 6124 12 8 8 CD cord-015369-72cjogxz 6124 13 ( ( -LRB- cord-015369-72cjogxz 6124 14 17.0 17.0 CD cord-015369-72cjogxz 6124 15 % % NN cord-015369-72cjogxz 6124 16 ) ) -RRB- cord-015369-72cjogxz 6124 17 improved improve VBN cord-015369-72cjogxz 6124 18 , , , cord-015369-72cjogxz 6124 19 whereas whereas IN cord-015369-72cjogxz 6124 20 unchanged unchanged JJ cord-015369-72cjogxz 6124 21 blushing blush VBG cord-015369-72cjogxz 6124 22 was be VBD cord-015369-72cjogxz 6124 23 found find VBN cord-015369-72cjogxz 6124 24 in in IN cord-015369-72cjogxz 6124 25 2 2 CD cord-015369-72cjogxz 6124 26 patients patient NNS cord-015369-72cjogxz 6124 27 ( ( -LRB- cord-015369-72cjogxz 6124 28 4.3 4.3 CD cord-015369-72cjogxz 6124 29 % % NN cord-015369-72cjogxz 6124 30 ) ) -RRB- cord-015369-72cjogxz 6124 31 . . . cord-015369-72cjogxz 6125 1 CS CS NNP cord-015369-72cjogxz 6125 2 was be VBD cord-015369-72cjogxz 6125 3 observed observe VBN cord-015369-72cjogxz 6125 4 in in IN cord-015369-72cjogxz 6125 5 20 20 CD cord-015369-72cjogxz 6125 6 patients patient NNS cord-015369-72cjogxz 6125 7 ( ( -LRB- cord-015369-72cjogxz 6125 8 42.6 42.6 CD cord-015369-72cjogxz 6125 9 % % NN cord-015369-72cjogxz 6125 10 ) ) -RRB- cord-015369-72cjogxz 6125 11 with with IN cord-015369-72cjogxz 6125 12 a a DT cord-015369-72cjogxz 6125 13 mean mean JJ cord-015369-72cjogxz 6125 14 VAS VAS NNP cord-015369-72cjogxz 6125 15 score score NN cord-015369-72cjogxz 6125 16 of of IN cord-015369-72cjogxz 6125 17 7.1 7.1 CD cord-015369-72cjogxz 6125 18 AE AE NNP cord-015369-72cjogxz 6125 19 2.0 2.0 CD cord-015369-72cjogxz 6125 20 at at IN cord-015369-72cjogxz 6125 21 follow follow VB cord-015369-72cjogxz 6125 22 up up RP cord-015369-72cjogxz 6125 23 . . . cord-015369-72cjogxz 6126 1 Twelve twelve CD cord-015369-72cjogxz 6126 2 patients patient NNS cord-015369-72cjogxz 6126 3 ( ( -LRB- cord-015369-72cjogxz 6126 4 25.5 25.5 CD cord-015369-72cjogxz 6126 5 % % NN cord-015369-72cjogxz 6126 6 ) ) -RRB- cord-015369-72cjogxz 6126 7 rated rate VBN cord-015369-72cjogxz 6126 8 CS CS NNP cord-015369-72cjogxz 6126 9 as as RB cord-015369-72cjogxz 6126 10 severe severe JJ cord-015369-72cjogxz 6126 11 and and CC cord-015369-72cjogxz 6126 12 another another DT cord-015369-72cjogxz 6126 13 2 2 CD cord-015369-72cjogxz 6126 14 patients patient NNS cord-015369-72cjogxz 6126 15 ( ( -LRB- cord-015369-72cjogxz 6126 16 4.3 4.3 CD cord-015369-72cjogxz 6126 17 % % NN cord-015369-72cjogxz 6126 18 ) ) -RRB- cord-015369-72cjogxz 6126 19 as as RB cord-015369-72cjogxz 6126 20 unbearable unbearable JJ cord-015369-72cjogxz 6126 21 . . . cord-015369-72cjogxz 6127 1 Two two CD cord-015369-72cjogxz 6127 2 patients patient NNS cord-015369-72cjogxz 6127 3 underwent undergo VBD cord-015369-72cjogxz 6127 4 clip clip NN cord-015369-72cjogxz 6127 5 removal removal NN cord-015369-72cjogxz 6127 6 with with IN cord-015369-72cjogxz 6127 7 improvement improvement NN cord-015369-72cjogxz 6127 8 of of IN cord-015369-72cjogxz 6127 9 CS CS NNP cord-015369-72cjogxz 6127 10 . . . cord-015369-72cjogxz 6128 1 Overall overall RB cord-015369-72cjogxz 6128 2 , , , cord-015369-72cjogxz 6128 3 93.6 93.6 CD cord-015369-72cjogxz 6128 4 % % NN cord-015369-72cjogxz 6128 5 would would MD cord-015369-72cjogxz 6128 6 recommend recommend VB cord-015369-72cjogxz 6128 7 this this DT cord-015369-72cjogxz 6128 8 surgical surgical JJ cord-015369-72cjogxz 6128 9 procedure procedure NN cord-015369-72cjogxz 6128 10 . . . cord-015369-72cjogxz 6129 1 Conclusions conclusion NNS cord-015369-72cjogxz 6129 2 . . . cord-015369-72cjogxz 6130 1 ESB ESB NNP cord-015369-72cjogxz 6130 2 at at IN cord-015369-72cjogxz 6130 3 the the DT cord-015369-72cjogxz 6130 4 2nd 2nd JJ cord-015369-72cjogxz 6130 5 ganglion ganglion NN cord-015369-72cjogxz 6130 6 presents present VBZ cord-015369-72cjogxz 6130 7 satisfying satisfy VBG cord-015369-72cjogxz 6130 8 postoperative postoperative JJ cord-015369-72cjogxz 6130 9 results result NNS cord-015369-72cjogxz 6130 10 for for IN cord-015369-72cjogxz 6130 11 the the DT cord-015369-72cjogxz 6130 12 vast vast JJ cord-015369-72cjogxz 6130 13 majority majority NN cord-015369-72cjogxz 6130 14 of of IN cord-015369-72cjogxz 6130 15 erythrophobic erythrophobic NNP cord-015369-72cjogxz 6130 16 patients patient NNS cord-015369-72cjogxz 6130 17 . . . cord-015369-72cjogxz 6131 1 Furthermore furthermore RB cord-015369-72cjogxz 6131 2 , , , cord-015369-72cjogxz 6131 3 clip clip NN cord-015369-72cjogxz 6131 4 removal removal NN cord-015369-72cjogxz 6131 5 offers offer VBZ cord-015369-72cjogxz 6131 6 reversibility reversibility NN cord-015369-72cjogxz 6131 7 of of IN cord-015369-72cjogxz 6131 8 unbearable unbearable JJ cord-015369-72cjogxz 6131 9 side side NN cord-015369-72cjogxz 6131 10 effects effect NNS cord-015369-72cjogxz 6131 11 as as IN cord-015369-72cjogxz 6131 12 CS CS NNP cord-015369-72cjogxz 6131 13 mainly mainly RB cord-015369-72cjogxz 6131 14 embarrasses embarrass VBZ cord-015369-72cjogxz 6131 15 patients patient NNS cord-015369-72cjogxz 6131 16 ' ' POS cord-015369-72cjogxz 6131 17 quality quality NN cord-015369-72cjogxz 6131 18 of of IN cord-015369-72cjogxz 6131 19 life life NN cord-015369-72cjogxz 6131 20 and and CC cord-015369-72cjogxz 6131 21 satisfaction satisfaction NN cord-015369-72cjogxz 6131 22 . . . cord-015369-72cjogxz 6132 1 Experiences experience NNS cord-015369-72cjogxz 6132 2 of of IN cord-015369-72cjogxz 6132 3 using use VBG cord-015369-72cjogxz 6132 4 V.A.C. V.A.C. NNP cord-015369-72cjogxz 6132 5 in in IN cord-015369-72cjogxz 6132 6 the the DT cord-015369-72cjogxz 6132 7 treatment treatment NN cord-015369-72cjogxz 6132 8 of of IN cord-015369-72cjogxz 6132 9 a a DT cord-015369-72cjogxz 6132 10 complicated complicated JJ cord-015369-72cjogxz 6132 11 , , , cord-015369-72cjogxz 6132 12 recurring recur VBG cord-015369-72cjogxz 6132 13 fistula fistula NN cord-015369-72cjogxz 6132 14 on on IN cord-015369-72cjogxz 6132 15 the the DT cord-015369-72cjogxz 6132 16 small small JJ cord-015369-72cjogxz 6132 17 intestine intestine NN cord-015369-72cjogxz 6132 18 after after IN cord-015369-72cjogxz 6132 19 severe severe JJ cord-015369-72cjogxz 6132 20 peritonitis peritonitis NN cord-015369-72cjogxz 6132 21 P. P. NNP cord-015369-72cjogxz 6132 22 Metzger Metzger NNP cord-015369-72cjogxz 6132 23 , , , cord-015369-72cjogxz 6132 24 M. M. NNP cord-015369-72cjogxz 6132 25 Bergmann Bergmann NNP cord-015369-72cjogxz 6132 26 , , , cord-015369-72cjogxz 6132 27 P. P. NNP cord-015369-72cjogxz 6132 28 Herbst Herbst NNP cord-015369-72cjogxz 6132 29 , , , cord-015369-72cjogxz 6132 30 H. H. NNP cord-015369-72cjogxz 6132 31 Rola Rola NNP cord-015369-72cjogxz 6132 32 , , , cord-015369-72cjogxz 6132 33 F. F. NNP cord-015369-72cjogxz 6132 34 Messenbäck Messenbäck NNP cord-015369-72cjogxz 6132 35 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6132 36 . . . cord-015369-72cjogxz 6133 1 Da Da NNP cord-015369-72cjogxz 6133 2 es es NNP cord-015369-72cjogxz 6133 3 kaum kaum NNP cord-015369-72cjogxz 6133 4 möglich möglich NNP cord-015369-72cjogxz 6134 1 ist ist NNP cord-015369-72cjogxz 6135 1 unterschiedliche unterschiedliche NN cord-015369-72cjogxz 6135 2 Wunden Wunden NNP cord-015369-72cjogxz 6135 3 miteinander miteinander NNP cord-015369-72cjogxz 6136 1 zu zu NNP cord-015369-72cjogxz 6136 2 vergleichen vergleichen NNP cord-015369-72cjogxz 6136 3 konnte konnte NNP cord-015369-72cjogxz 6136 4 kein kein NNP cord-015369-72cjogxz 6136 5 signifikanter signifikanter NNP cord-015369-72cjogxz 6136 6 Unterschied Unterschied NNP cord-015369-72cjogxz 6136 7 zwischen zwischen NNP cord-015369-72cjogxz 6136 8 den den NN cord-015369-72cjogxz 6136 9 einzelnen einzelnen NNP cord-015369-72cjogxz 6136 10 Systemen Systemen NNP cord-015369-72cjogxz 6136 11 gefunden gefunden NN cord-015369-72cjogxz 6136 12 werden werden NNP cord-015369-72cjogxz 6136 13 . . . cord-015369-72cjogxz 6137 1 Auch Auch NNP cord-015369-72cjogxz 6137 2 bei bei NNP cord-015369-72cjogxz 6137 3 gleichartigen gleichartigen NNP cord-015369-72cjogxz 6137 4 Wunden Wunden NNP cord-015369-72cjogxz 6137 5 , , , cord-015369-72cjogxz 6137 6 bei bei NNP cord-015369-72cjogxz 6137 7 demselben demselben NNP cord-015369-72cjogxz 6137 8 Patienten Patienten NNP cord-015369-72cjogxz 6137 9 konnte konnte NNP cord-015369-72cjogxz 6137 10 kein kein NNP cord-015369-72cjogxz 6137 11 wesentlicher wesentlicher NN cord-015369-72cjogxz 6137 12 Vorteil Vorteil NNP cord-015369-72cjogxz 6137 13 eines eines NNP cord-015369-72cjogxz 6137 14 spezifischen spezifischen NNP cord-015369-72cjogxz 6137 15 Systems Systems NNPS cord-015369-72cjogxz 6137 16 herausgearbeitet herausgearbeitet NNP cord-015369-72cjogxz 6137 17 werden werden NNP cord-015369-72cjogxz 6137 18 . . . cord-015369-72cjogxz 6138 1 Die die VB cord-015369-72cjogxz 6138 2 Unterschiede Unterschiede NNP cord-015369-72cjogxz 6138 3 beschränken beschränken VBD cord-015369-72cjogxz 6138 4 sich sich NNP cord-015369-72cjogxz 6138 5 somit somit NNP cord-015369-72cjogxz 6138 6 auf auf NNP cord-015369-72cjogxz 6138 7 Bedienerfreundlichkeit Bedienerfreundlichkeit NNP cord-015369-72cjogxz 6138 8 , , , cord-015369-72cjogxz 6138 9 Schmerzmanagement Schmerzmanagement NNP cord-015369-72cjogxz 6138 10 , , , cord-015369-72cjogxz 6139 1 Patientenkomfort Patientenkomfort NNP cord-015369-72cjogxz 6139 2 und und IN cord-015369-72cjogxz 6140 1 auf auf NNP cord-015369-72cjogxz 6140 2 die die VBP cord-015369-72cjogxz 6140 3 Kostenfrage Kostenfrage NNP cord-015369-72cjogxz 6140 4 . . . cord-015369-72cjogxz 6141 1 Background background NN cord-015369-72cjogxz 6141 2 . . . cord-015369-72cjogxz 6142 1 Around around RB cord-015369-72cjogxz 6142 2 one one CD cord-015369-72cjogxz 6142 3 percent percent NN cord-015369-72cjogxz 6142 4 of of IN cord-015369-72cjogxz 6142 5 people people NNS cord-015369-72cjogxz 6142 6 in in IN cord-015369-72cjogxz 6142 7 industrialised industrialised JJ cord-015369-72cjogxz 6142 8 countries country NNS cord-015369-72cjogxz 6142 9 will will MD cord-015369-72cjogxz 6142 10 suffer suffer VB cord-015369-72cjogxz 6142 11 from from IN cord-015369-72cjogxz 6142 12 a a DT cord-015369-72cjogxz 6142 13 leg leg NN cord-015369-72cjogxz 6142 14 ulcer ulcer NN cord-015369-72cjogxz 6142 15 at at IN cord-015369-72cjogxz 6142 16 some some DT cord-015369-72cjogxz 6142 17 time time NN cord-015369-72cjogxz 6142 18 . . . cord-015369-72cjogxz 6143 1 The the DT cord-015369-72cjogxz 6143 2 majority majority NN cord-015369-72cjogxz 6143 3 of of IN cord-015369-72cjogxz 6143 4 these these DT cord-015369-72cjogxz 6143 5 leg leg NN cord-015369-72cjogxz 6143 6 ulcers ulcer NNS cord-015369-72cjogxz 6143 7 are be VBP cord-015369-72cjogxz 6143 8 due due JJ cord-015369-72cjogxz 6143 9 to to IN cord-015369-72cjogxz 6143 10 venous venous JJ cord-015369-72cjogxz 6143 11 problems problem NNS cord-015369-72cjogxz 6143 12 and and CC cord-015369-72cjogxz 6143 13 are be VBP cord-015369-72cjogxz 6143 14 so so RB cord-015369-72cjogxz 6143 15 called call VBN cord-015369-72cjogxz 6143 16 venous venous JJ cord-015369-72cjogxz 6143 17 ulcers ulcer NNS cord-015369-72cjogxz 6143 18 . . . cord-015369-72cjogxz 6144 1 The the DT cord-015369-72cjogxz 6144 2 main main JJ cord-015369-72cjogxz 6144 3 treatment treatment NN cord-015369-72cjogxz 6144 4 has have VBZ cord-015369-72cjogxz 6144 5 been be VBN cord-015369-72cjogxz 6144 6 a a DT cord-015369-72cjogxz 6144 7 firm firm JJ cord-015369-72cjogxz 6144 8 compression compression NN cord-015369-72cjogxz 6144 9 and and CC cord-015369-72cjogxz 6144 10 classical classical JJ cord-015369-72cjogxz 6144 11 wound wound NN cord-015369-72cjogxz 6144 12 dressings dressing NNS cord-015369-72cjogxz 6144 13 . . . cord-015369-72cjogxz 6145 1 Additional additional JJ cord-015369-72cjogxz 6145 2 methods method NNS cord-015369-72cjogxz 6145 3 like like IN cord-015369-72cjogxz 6145 4 vacuum vacuum NN cord-015369-72cjogxz 6145 5 assisted assist VBN cord-015369-72cjogxz 6145 6 closure closure NN cord-015369-72cjogxz 6145 7 ( ( -LRB- cord-015369-72cjogxz 6145 8 V.A.C. V.A.C. NNP cord-015369-72cjogxz 6145 9 ) ) -RRB- cord-015369-72cjogxz 6145 10 are be VBP cord-015369-72cjogxz 6145 11 established establish VBN cord-015369-72cjogxz 6145 12 in in IN cord-015369-72cjogxz 6145 13 the the DT cord-015369-72cjogxz 6145 14 management management NN cord-015369-72cjogxz 6145 15 of of IN cord-015369-72cjogxz 6145 16 acute acute JJ cord-015369-72cjogxz 6145 17 and and CC cord-015369-72cjogxz 6145 18 chronic chronic JJ cord-015369-72cjogxz 6145 19 wounds wound NNS cord-015369-72cjogxz 6145 20 . . . cord-015369-72cjogxz 6146 1 We -PRON- PRP cord-015369-72cjogxz 6146 2 report report VBP cord-015369-72cjogxz 6146 3 on on IN cord-015369-72cjogxz 6146 4 a a DT cord-015369-72cjogxz 6146 5 case case NN cord-015369-72cjogxz 6146 6 where where WRB cord-015369-72cjogxz 6146 7 V.A.C. V.A.C. NNP cord-015369-72cjogxz 6146 8 was be VBD cord-015369-72cjogxz 6146 9 used use VBN cord-015369-72cjogxz 6146 10 in in IN cord-015369-72cjogxz 6146 11 a a DT cord-015369-72cjogxz 6146 12 66-years 66-years CD cord-015369-72cjogxz 6146 13 old old JJ cord-015369-72cjogxz 6146 14 female female JJ cord-015369-72cjogxz 6146 15 patient patient NN cord-015369-72cjogxz 6146 16 with with IN cord-015369-72cjogxz 6146 17 severe severe JJ cord-015369-72cjogxz 6146 18 sepsis sepsis NN cord-015369-72cjogxz 6146 19 . . . cord-015369-72cjogxz 6147 1 Methods method NNS cord-015369-72cjogxz 6147 2 . . . cord-015369-72cjogxz 6148 1 The the DT cord-015369-72cjogxz 6148 2 patient patient NN cord-015369-72cjogxz 6148 3 was be VBD cord-015369-72cjogxz 6148 4 transferred transfer VBN cord-015369-72cjogxz 6148 5 to to IN cord-015369-72cjogxz 6148 6 our -PRON- PRP$ cord-015369-72cjogxz 6148 7 hospital hospital NN cord-015369-72cjogxz 6148 8 with with IN cord-015369-72cjogxz 6148 9 a a DT cord-015369-72cjogxz 6148 10 haemorrhagic haemorrhagic JJ cord-015369-72cjogxz 6148 11 shock shock NN cord-015369-72cjogxz 6148 12 due due IN cord-015369-72cjogxz 6148 13 to to IN cord-015369-72cjogxz 6148 14 a a DT cord-015369-72cjogxz 6148 15 bleeding bleeding NN cord-015369-72cjogxz 6148 16 of of IN cord-015369-72cjogxz 6148 17 a a DT cord-015369-72cjogxz 6148 18 giant giant JJ cord-015369-72cjogxz 6148 19 septic septic JJ cord-015369-72cjogxz 6148 20 venous venous JJ cord-015369-72cjogxz 6148 21 leg leg NN cord-015369-72cjogxz 6148 22 ulcer ulcer NN cord-015369-72cjogxz 6148 23 . . . cord-015369-72cjogxz 6149 1 We -PRON- PRP cord-015369-72cjogxz 6149 2 performed perform VBD cord-015369-72cjogxz 6149 3 haemostasis haemostasis NN cord-015369-72cjogxz 6149 4 and and CC cord-015369-72cjogxz 6149 5 initial initial JJ cord-015369-72cjogxz 6149 6 necrectomy necrectomy NN cord-015369-72cjogxz 6149 7 under under IN cord-015369-72cjogxz 6149 8 high high JJ cord-015369-72cjogxz 6149 9 dose dose NN cord-015369-72cjogxz 6149 10 antibiotic antibiotic JJ cord-015369-72cjogxz 6149 11 therapy therapy NN cord-015369-72cjogxz 6149 12 followed follow VBN cord-015369-72cjogxz 6149 13 by by IN cord-015369-72cjogxz 6149 14 two two CD cord-015369-72cjogxz 6149 15 weeks week NNS cord-015369-72cjogxz 6149 16 V.A.C. V.A.C. NNP cord-015369-72cjogxz 6149 17 therapy therapy NN cord-015369-72cjogxz 6149 18 . . . cord-015369-72cjogxz 6150 1 In in IN cord-015369-72cjogxz 6150 2 two two CD cord-015369-72cjogxz 6150 3 consequent consequent JJ cord-015369-72cjogxz 6150 4 operations operation NNS cord-015369-72cjogxz 6150 5 we -PRON- PRP cord-015369-72cjogxz 6150 6 performed perform VBD cord-015369-72cjogxz 6150 7 mesh mesh NN cord-015369-72cjogxz 6150 8 grafting grafting NN cord-015369-72cjogxz 6150 9 of of IN cord-015369-72cjogxz 6150 10 the the DT cord-015369-72cjogxz 6150 11 defect defect NN cord-015369-72cjogxz 6150 12 . . . cord-015369-72cjogxz 6151 1 Results result NNS cord-015369-72cjogxz 6151 2 . . . cord-015369-72cjogxz 6152 1 Grafts graft NNS cord-015369-72cjogxz 6152 2 showed show VBD cord-015369-72cjogxz 6152 3 complete complete JJ cord-015369-72cjogxz 6152 4 take take NN cord-015369-72cjogxz 6152 5 - - HYPH cord-015369-72cjogxz 6152 6 rate rate NN cord-015369-72cjogxz 6152 7 . . . cord-015369-72cjogxz 6153 1 After after IN cord-015369-72cjogxz 6153 2 a a DT cord-015369-72cjogxz 6153 3 total total JJ cord-015369-72cjogxz 6153 4 stay stay NN cord-015369-72cjogxz 6153 5 of of IN cord-015369-72cjogxz 6153 6 two two CD cord-015369-72cjogxz 6153 7 months month NNS cord-015369-72cjogxz 6153 8 the the DT cord-015369-72cjogxz 6153 9 patient patient NN cord-015369-72cjogxz 6153 10 was be VBD cord-015369-72cjogxz 6153 11 discharged discharge VBN cord-015369-72cjogxz 6153 12 from from IN cord-015369-72cjogxz 6153 13 hospital hospital NN cord-015369-72cjogxz 6153 14 in in IN cord-015369-72cjogxz 6153 15 good good JJ cord-015369-72cjogxz 6153 16 condition condition NN cord-015369-72cjogxz 6153 17 and and CC cord-015369-72cjogxz 6153 18 with with IN cord-015369-72cjogxz 6153 19 totally totally RB cord-015369-72cjogxz 6153 20 healed heal VBN cord-015369-72cjogxz 6153 21 ulcer ulcer NN cord-015369-72cjogxz 6153 22 . . . cord-015369-72cjogxz 6154 1 Conclusions conclusion NNS cord-015369-72cjogxz 6154 2 . . . cord-015369-72cjogxz 6155 1 V.A.C. V.A.C. NNP cord-015369-72cjogxz 6155 2 therapy therapy NN cord-015369-72cjogxz 6155 3 was be VBD cord-015369-72cjogxz 6155 4 rapidly rapidly RB cord-015369-72cjogxz 6155 5 efficacious efficacious JJ cord-015369-72cjogxz 6155 6 in in IN cord-015369-72cjogxz 6155 7 cleaning clean VBG cord-015369-72cjogxz 6155 8 the the DT cord-015369-72cjogxz 6155 9 wound wound NN cord-015369-72cjogxz 6155 10 , , , cord-015369-72cjogxz 6155 11 promoting promote VBG cord-015369-72cjogxz 6155 12 angiogenesis angiogenesis NN cord-015369-72cjogxz 6155 13 and and CC cord-015369-72cjogxz 6155 14 the the DT cord-015369-72cjogxz 6155 15 formation formation NN cord-015369-72cjogxz 6155 16 of of IN cord-015369-72cjogxz 6155 17 healthy healthy JJ cord-015369-72cjogxz 6155 18 tissue tissue NN cord-015369-72cjogxz 6155 19 . . . cord-015369-72cjogxz 6156 1 Negative negative JJ cord-015369-72cjogxz 6156 2 - - HYPH cord-015369-72cjogxz 6156 3 pressure pressure NN cord-015369-72cjogxz 6156 4 wound wound NN cord-015369-72cjogxz 6156 5 treatment treatment NN cord-015369-72cjogxz 6156 6 may may MD cord-015369-72cjogxz 6156 7 accelerate accelerate VB cord-015369-72cjogxz 6156 8 closure closure NN cord-015369-72cjogxz 6156 9 of of IN cord-015369-72cjogxz 6156 10 large large JJ cord-015369-72cjogxz 6156 11 leg leg NN cord-015369-72cjogxz 6156 12 wounds wound NNS cord-015369-72cjogxz 6156 13 even even RB cord-015369-72cjogxz 6156 14 in in IN cord-015369-72cjogxz 6156 15 septic septic JJ cord-015369-72cjogxz 6156 16 ulcers ulcer NNS cord-015369-72cjogxz 6156 17 . . . cord-015369-72cjogxz 6157 1 A a DT cord-015369-72cjogxz 6157 2 close close JJ cord-015369-72cjogxz 6157 3 monitoring monitoring NN cord-015369-72cjogxz 6157 4 in in IN cord-015369-72cjogxz 6157 5 these these DT cord-015369-72cjogxz 6157 6 patients patient NNS cord-015369-72cjogxz 6157 7 is be VBZ cord-015369-72cjogxz 6157 8 mandatory mandatory JJ cord-015369-72cjogxz 6157 9 . . . cord-015369-72cjogxz 6158 1 In in IN cord-015369-72cjogxz 6158 2 such such JJ cord-015369-72cjogxz 6158 3 situations situation NNS cord-015369-72cjogxz 6158 4 V.A.C. V.A.C. NNP cord-015369-72cjogxz 6158 5 can can MD cord-015369-72cjogxz 6158 6 be be VB cord-015369-72cjogxz 6158 7 seen see VBN cord-015369-72cjogxz 6158 8 as as IN cord-015369-72cjogxz 6158 9 a a DT cord-015369-72cjogxz 6158 10 salvage salvage NN cord-015369-72cjogxz 6158 11 procedure procedure NN cord-015369-72cjogxz 6158 12 to to TO cord-015369-72cjogxz 6158 13 avoid avoid VB cord-015369-72cjogxz 6158 14 amputation amputation NN cord-015369-72cjogxz 6158 15 of of IN cord-015369-72cjogxz 6158 16 the the DT cord-015369-72cjogxz 6158 17 lower low JJR cord-015369-72cjogxz 6158 18 extremity extremity NN cord-015369-72cjogxz 6158 19 and and CC cord-015369-72cjogxz 6158 20 to to TO cord-015369-72cjogxz 6158 21 maintain maintain VB cord-015369-72cjogxz 6158 22 patients patient NNS cord-015369-72cjogxz 6158 23 ' ' POS cord-015369-72cjogxz 6158 24 quality quality NN cord-015369-72cjogxz 6158 25 of of IN cord-015369-72cjogxz 6158 26 life life NN cord-015369-72cjogxz 6158 27 . . . cord-015369-72cjogxz 6159 1 Further further JJ cord-015369-72cjogxz 6159 2 reports report NNS cord-015369-72cjogxz 6159 3 in in IN cord-015369-72cjogxz 6159 4 large large JJ cord-015369-72cjogxz 6159 5 series serie NNS cord-015369-72cjogxz 6159 6 are be VBP cord-015369-72cjogxz 6159 7 necessary necessary JJ cord-015369-72cjogxz 6159 8 to to TO cord-015369-72cjogxz 6159 9 confirm confirm VB cord-015369-72cjogxz 6159 10 our -PRON- PRP$ cord-015369-72cjogxz 6159 11 results result NNS cord-015369-72cjogxz 6159 12 . . . cord-015369-72cjogxz 6160 1 Schwerste Schwerste NNP cord-015369-72cjogxz 6160 2 Arm Arm NNP cord-015369-72cjogxz 6160 3 - - HYPH cord-015369-72cjogxz 6160 4 und und NNP cord-015369-72cjogxz 6160 5 Brustbandphlegmone Brustbandphlegmone NNP cord-015369-72cjogxz 6160 6 nach nach NNP cord-015369-72cjogxz 6160 7 Insektenstich Insektenstich NNP cord-015369-72cjogxz 6160 8 : : : cord-015369-72cjogxz 6161 1 Behandlungskonzept Behandlungskonzept NNP cord-015369-72cjogxz 6161 2 offene offene NNP cord-015369-72cjogxz 6161 3 Wundbehandlung Wundbehandlung NNP cord-015369-72cjogxz 6161 4 nach nach NNP cord-015369-72cjogxz 6161 5 Eröffnung Eröffnung NNP cord-015369-72cjogxz 6162 1 sämtlicher sämtlicher NNP cord-015369-72cjogxz 6162 2 Nervenengstellen Nervenengstellen NNP cord-015369-72cjogxz 6162 3 und und XX cord-015369-72cjogxz 6163 1 Debridement Debridement NNP cord-015369-72cjogxz 6163 2 der der NNP cord-015369-72cjogxz 6164 1 nekrotischen nekrotischen NNP cord-015369-72cjogxz 6165 1 Gewebe Gewebe NNP cord-015369-72cjogxz 6165 2 A. a. NN cord-015369-72cjogxz 6165 3 Obiltschnig Obiltschnig NNP cord-015369-72cjogxz 6165 4 Bei Bei NNP cord-015369-72cjogxz 6166 1 einem einem NNP cord-015369-72cjogxz 6167 1 immunsupprimierten immunsupprimierten NNP cord-015369-72cjogxz 6167 2 Patienten Patienten NNP cord-015369-72cjogxz 6167 3 kam kam NNP cord-015369-72cjogxz 6168 1 es es NNP cord-015369-72cjogxz 6168 2 nach nach NNP cord-015369-72cjogxz 6168 3 einem einem NNP cord-015369-72cjogxz 6168 4 Insektenstich Insektenstich NNP cord-015369-72cjogxz 6168 5 am be VBP cord-015369-72cjogxz 6168 6 Ellbogen Ellbogen NNP cord-015369-72cjogxz 6168 7 zu zu NNP cord-015369-72cjogxz 6168 8 einer einer NNP cord-015369-72cjogxz 6168 9 massivsten massivsten NNP cord-015369-72cjogxz 6168 10 rasch rasch NNP cord-015369-72cjogxz 6168 11 auftretenden auftretenden NNP cord-015369-72cjogxz 6168 12 Phlegmone Phlegmone NNP cord-015369-72cjogxz 6168 13 des des FW cord-015369-72cjogxz 6168 14 gesamten gesamten NNP cord-015369-72cjogxz 6168 15 Arms Arms NNP cord-015369-72cjogxz 6168 16 und und NNP cord-015369-72cjogxz 6168 17 der der NNP cord-015369-72cjogxz 6168 18 Brustwand Brustwand NNP cord-015369-72cjogxz 6168 19 . . . cord-015369-72cjogxz 6169 1 Der Der NNP cord-015369-72cjogxz 6169 2 Patient Patient NNP cord-015369-72cjogxz 6169 3 wurde wurde NN cord-015369-72cjogxz 6169 4 zur zur NNP cord-015369-72cjogxz 6169 5 Therapie Therapie NNP cord-015369-72cjogxz 6169 6 ins ins NNP cord-015369-72cjogxz 6169 7 Zentralkrankenhaus Zentralkrankenhaus NNP cord-015369-72cjogxz 6169 8 eingeliefert eingeliefert NN cord-015369-72cjogxz 6169 9 . . . cord-015369-72cjogxz 6170 1 Es Es NNP cord-015369-72cjogxz 6170 2 hätte hätte NNP cord-015369-72cjogxz 6170 3 primär primär NNP cord-015369-72cjogxz 6170 4 nur nur NNP cord-015369-72cjogxz 6170 5 eine eine NNP cord-015369-72cjogxz 6170 6 Exarticulation Exarticulation NNP cord-015369-72cjogxz 6171 1 i -PRON- PRP cord-015369-72cjogxz 6171 2 m be VBP cord-015369-72cjogxz 6171 3 Bereich Bereich NNP cord-015369-72cjogxz 6171 4 des des NNP cord-015369-72cjogxz 6172 1 rechten rechten NNP cord-015369-72cjogxz 6172 2 Schultergelenkes Schultergelenkes NNP cord-015369-72cjogxz 6172 3 durchgeführt durchgeführt NN cord-015369-72cjogxz 6172 4 werden werden NNP cord-015369-72cjogxz 6172 5 können können NNP cord-015369-72cjogxz 6172 6 . . . cord-015369-72cjogxz 6173 1 Hier Hier NNP cord-015369-72cjogxz 6173 2 wäre wäre NNP cord-015369-72cjogxz 6173 3 die die VBP cord-015369-72cjogxz 6173 4 Hautdeckung Hautdeckung NNP cord-015369-72cjogxz 6173 5 jedoch jedoch NNP cord-015369-72cjogxz 6173 6 immens immens NNP cord-015369-72cjogxz 6173 7 schwierig schwierig NNP cord-015369-72cjogxz 6173 8 gewesen gewesen NNP cord-015369-72cjogxz 6173 9 . . . cord-015369-72cjogxz 6174 1 Aus Aus NNP cord-015369-72cjogxz 6174 2 diesem diesem JJ cord-015369-72cjogxz 6174 3 Grund Grund NNP cord-015369-72cjogxz 6174 4 wurde wurde NN cord-015369-72cjogxz 6174 5 primär primär NNP cord-015369-72cjogxz 6174 6 eine eine NNP cord-015369-72cjogxz 6174 7 ausgedehnte ausgedehnte NNP cord-015369-72cjogxz 6175 1 Nekrektomie Nekrektomie NNP cord-015369-72cjogxz 6176 1 i -PRON- PRP cord-015369-72cjogxz 6176 2 m be VBP cord-015369-72cjogxz 6176 3 Bereich Bereich NNP cord-015369-72cjogxz 6176 4 des des NNP cord-015369-72cjogxz 6176 5 gesamten gesamten NNP cord-015369-72cjogxz 6176 6 Armes Armes NNP cord-015369-72cjogxz 6176 7 durchgeführt durchgeführt NN cord-015369-72cjogxz 6176 8 . . . cord-015369-72cjogxz 6177 1 Zusätzlich Zusätzlich NNP cord-015369-72cjogxz 6177 2 die die VBP cord-015369-72cjogxz 6177 3 Eröffnung Eröffnung NNP cord-015369-72cjogxz 6177 4 sämtlicher sämtlicher NNP cord-015369-72cjogxz 6177 5 Nervenengstellen Nervenengstellen NNP cord-015369-72cjogxz 6177 6 in in IN cord-015369-72cjogxz 6177 7 der der NNP cord-015369-72cjogxz 6177 8 Höhe Höhe NNP cord-015369-72cjogxz 6177 9 des des FW cord-015369-72cjogxz 6177 10 Handgelenkes Handgelenkes NNP cord-015369-72cjogxz 6177 11 , , , cord-015369-72cjogxz 6177 12 des des FW cord-015369-72cjogxz 6177 13 Ellbogengelenkes Ellbogengelenkes NNP cord-015369-72cjogxz 6177 14 und und XX cord-015369-72cjogxz 6177 15 in in IN cord-015369-72cjogxz 6177 16 der der NNP cord-015369-72cjogxz 6177 17 Axilla Axilla NNP cord-015369-72cjogxz 6177 18 . . . cord-015369-72cjogxz 6178 1 Postoperativ postoperativ JJ cord-015369-72cjogxz 6178 2 wurden wurden NNS cord-015369-72cjogxz 6178 3 die die VBP cord-015369-72cjogxz 6178 4 Vitalparameter Vitalparameter NNP cord-015369-72cjogxz 6178 5 in in IN cord-015369-72cjogxz 6178 6 der der NNP cord-015369-72cjogxz 6178 7 Intensivstation Intensivstation NNP cord-015369-72cjogxz 6178 8 überwacht überwacht NN cord-015369-72cjogxz 6178 9 und und NNP cord-015369-72cjogxz 6178 10 eine eine NNP cord-015369-72cjogxz 6178 11 gezielte gezielte NNP cord-015369-72cjogxz 6178 12 Antibiose Antibiose NNP cord-015369-72cjogxz 6178 13 durchgeführt durchgeführt NN cord-015369-72cjogxz 6178 14 . . . cord-015369-72cjogxz 6179 1 Mit Mit NNP cord-015369-72cjogxz 6179 2 unterstützenden unterstützenden NNP cord-015369-72cjogxz 6179 3 Hilfsmaßnahmen Hilfsmaßnahmen NNP cord-015369-72cjogxz 6179 4 ( ( -LRB- cord-015369-72cjogxz 6179 5 Niere Niere NNP cord-015369-72cjogxz 6179 6 , , , cord-015369-72cjogxz 6179 7 Lunge Lunge NNP cord-015369-72cjogxz 6179 8 ) ) -RRB- cord-015369-72cjogxz 6179 9 konnte konnte NNP cord-015369-72cjogxz 6179 10 eine eine NNP cord-015369-72cjogxz 6179 11 Normalisierung Normalisierung NNP cord-015369-72cjogxz 6179 12 der der NNP cord-015369-72cjogxz 6179 13 entzündlichen entzündlichen NNP cord-015369-72cjogxz 6179 14 Parameter Parameter NNP cord-015369-72cjogxz 6179 15 erreicht erreicht NNP cord-015369-72cjogxz 6179 16 werden werden NNP cord-015369-72cjogxz 6179 17 . . . cord-015369-72cjogxz 6180 1 Die die VB cord-015369-72cjogxz 6180 2 Nachbehandlung Nachbehandlung NNP cord-015369-72cjogxz 6180 3 der der NNP cord-015369-72cjogxz 6180 4 Hand Hand NNP cord-015369-72cjogxz 6180 5 erfolgte erfolgte NN cord-015369-72cjogxz 6180 6 offen offen NNP cord-015369-72cjogxz 6180 7 . . . cord-015369-72cjogxz 6181 1 Es Es NNP cord-015369-72cjogxz 6181 2 erfolgten erfolgten NNP cord-015369-72cjogxz 6181 3 keine keine NNP cord-015369-72cjogxz 6181 4 Hauttransplantationen Hauttransplantationen NNP cord-015369-72cjogxz 6181 5 , , , cord-015369-72cjogxz 6181 6 sondern sondern NNP cord-015369-72cjogxz 6181 7 nur nur NNP cord-015369-72cjogxz 6181 8 die die VBP cord-015369-72cjogxz 6181 9 offene offene NNP cord-015369-72cjogxz 6181 10 Wundbehandlung Wundbehandlung NNP cord-015369-72cjogxz 6181 11 . . . cord-015369-72cjogxz 6182 1 Mit Mit NNP cord-015369-72cjogxz 6182 2 dieser dieser NNP cord-015369-72cjogxz 6182 3 Behandlung Behandlung NNP cord-015369-72cjogxz 6183 1 ( ( -LRB- cord-015369-72cjogxz 6183 2 Waschung Waschung NNP cord-015369-72cjogxz 6183 3 -Lokalmaßnahmen -Lokalmaßnahmen NNPS cord-015369-72cjogxz 6183 4 ) ) -RRB- cord-015369-72cjogxz 6183 5 konnte konnte NNP cord-015369-72cjogxz 6183 6 ein ein NNP cord-015369-72cjogxz 6183 7 völliger völliger NN cord-015369-72cjogxz 6183 8 Verschluss Verschluss NNP cord-015369-72cjogxz 6183 9 der der NNP cord-015369-72cjogxz 6183 10 Wunde Wunde NNP cord-015369-72cjogxz 6183 11 erreicht erreicht NN cord-015369-72cjogxz 6183 12 werden werden NNP cord-015369-72cjogxz 6184 1 und und NNP cord-015369-72cjogxz 6184 2 es es NNP cord-015369-72cjogxz 6184 3 wurde wurde NNP cord-015369-72cjogxz 6185 1 auch auch NNP cord-015369-72cjogxz 6185 2 die die VBP cord-015369-72cjogxz 6185 3 Funktion Funktion NNP cord-015369-72cjogxz 6185 4 der der NN cord-015369-72cjogxz 6185 5 Hand Hand NNP cord-015369-72cjogxz 6185 6 wiederhergestellt wiederhergestellt JJS cord-015369-72cjogxz 6185 7 . . . cord-015369-72cjogxz 6186 1 Anhand Anhand NNP cord-015369-72cjogxz 6186 2 dieses dieses NNP cord-015369-72cjogxz 6186 3 Fallbeispieles Fallbeispieles NNP cord-015369-72cjogxz 6186 4 sollte sollte NNP cord-015369-72cjogxz 6186 5 eben eben NNP cord-015369-72cjogxz 6186 6 die die VBP cord-015369-72cjogxz 6186 7 offene offene NNP cord-015369-72cjogxz 6186 8 Wundbehandlung Wundbehandlung NNP cord-015369-72cjogxz 6186 9 bei bei NNP cord-015369-72cjogxz 6186 10 Infektionen Infektionen NNP cord-015369-72cjogxz 6187 1 auch auch NNP cord-015369-72cjogxz 6187 2 mit mit NNP cord-015369-72cjogxz 6187 3 Eröffnung Eröffnung NNP cord-015369-72cjogxz 6187 4 der der NNP cord-015369-72cjogxz 6187 5 Nervenengstellen Nervenengstellen NNP cord-015369-72cjogxz 6188 1 diskutiert diskutiert NNP cord-015369-72cjogxz 6188 2 werden werden NNP cord-015369-72cjogxz 6188 3 . . . cord-015369-72cjogxz 6189 1 Methods method NNS cord-015369-72cjogxz 6189 2 . . . cord-015369-72cjogxz 6190 1 A a DT cord-015369-72cjogxz 6190 2 retrospective retrospective JJ cord-015369-72cjogxz 6190 3 review review NN cord-015369-72cjogxz 6190 4 was be VBD cord-015369-72cjogxz 6190 5 performed perform VBN cord-015369-72cjogxz 6190 6 on on IN cord-015369-72cjogxz 6190 7 1601 1601 CD cord-015369-72cjogxz 6190 8 patients patient NNS cord-015369-72cjogxz 6190 9 , , , cord-015369-72cjogxz 6190 10 who who WP cord-015369-72cjogxz 6190 11 suffered suffer VBD cord-015369-72cjogxz 6190 12 a a DT cord-015369-72cjogxz 6190 13 bite bite NN cord-015369-72cjogxz 6190 14 injury injury NN cord-015369-72cjogxz 6190 15 during during IN cord-015369-72cjogxz 6190 16 January January NNP cord-015369-72cjogxz 6190 17 1992 1992 CD cord-015369-72cjogxz 6190 18 to to IN cord-015369-72cjogxz 6190 19 December December NNP cord-015369-72cjogxz 6190 20 2008 2008 CD cord-015369-72cjogxz 6190 21 . . . cord-015369-72cjogxz 6191 1 There there EX cord-015369-72cjogxz 6191 2 were be VBD cord-015369-72cjogxz 6191 3 881 881 CD cord-015369-72cjogxz 6191 4 males male NNS cord-015369-72cjogxz 6191 5 and and CC cord-015369-72cjogxz 6191 6 720 720 CD cord-015369-72cjogxz 6191 7 females female NNS cord-015369-72cjogxz 6191 8 , , , cord-015369-72cjogxz 6191 9 average average JJ cord-015369-72cjogxz 6191 10 age age NN cord-015369-72cjogxz 6191 11 of of IN cord-015369-72cjogxz 6191 12 7.2 7.2 CD cord-015369-72cjogxz 6191 13 years year NNS cord-015369-72cjogxz 6191 14 ( ( -LRB- cord-015369-72cjogxz 6191 15 range range VBP cord-015369-72cjogxz 6191 16 0 0 CD cord-015369-72cjogxz 6191 17 - - SYM cord-015369-72cjogxz 6191 18 18 18 CD cord-015369-72cjogxz 6191 19 years year NNS cord-015369-72cjogxz 6191 20 ) ) -RRB- cord-015369-72cjogxz 6191 21 . . . cord-015369-72cjogxz 6192 1 The the DT cord-015369-72cjogxz 6192 2 most most RBS cord-015369-72cjogxz 6192 3 frequent frequent JJ cord-015369-72cjogxz 6192 4 site site NN cord-015369-72cjogxz 6192 5 of of IN cord-015369-72cjogxz 6192 6 injury injury NN cord-015369-72cjogxz 6192 7 were be VBD cord-015369-72cjogxz 6192 8 the the DT cord-015369-72cjogxz 6192 9 face face NN cord-015369-72cjogxz 6192 10 and and CC cord-015369-72cjogxz 6192 11 the the DT cord-015369-72cjogxz 6192 12 upper upper JJ cord-015369-72cjogxz 6192 13 extremities extremity NNS cord-015369-72cjogxz 6192 14 , , , cord-015369-72cjogxz 6192 15 more more JJR cord-015369-72cjogxz 6192 16 than than IN cord-015369-72cjogxz 6192 17 half half NN cord-015369-72cjogxz 6192 18 of of IN cord-015369-72cjogxz 6192 19 the the DT cord-015369-72cjogxz 6192 20 victims victim NNS cord-015369-72cjogxz 6192 21 were be VBD cord-015369-72cjogxz 6192 22 bitten bite VBN cord-015369-72cjogxz 6192 23 by by IN cord-015369-72cjogxz 6192 24 their -PRON- PRP$ cord-015369-72cjogxz 6192 25 pets pet NNS cord-015369-72cjogxz 6192 26 . . . cord-015369-72cjogxz 6193 1 Bite bite NN cord-015369-72cjogxz 6193 2 injuries injury NNS cord-015369-72cjogxz 6193 3 ranged range VBD cord-015369-72cjogxz 6193 4 from from IN cord-015369-72cjogxz 6193 5 relatively relatively RB cord-015369-72cjogxz 6193 6 minor minor JJ cord-015369-72cjogxz 6193 7 wounds wound NNS cord-015369-72cjogxz 6193 8 to to IN cord-015369-72cjogxz 6193 9 major major JJ cord-015369-72cjogxz 6193 10 injuries injury NNS cord-015369-72cjogxz 6193 11 , , , cord-015369-72cjogxz 6193 12 that that WDT cord-015369-72cjogxz 6193 13 included include VBD cord-015369-72cjogxz 6193 14 open open JJ cord-015369-72cjogxz 6193 15 fractures fracture NNS cord-015369-72cjogxz 6193 16 , , , cord-015369-72cjogxz 6193 17 nerve nerve NN cord-015369-72cjogxz 6193 18 and and CC cord-015369-72cjogxz 6193 19 tendon tendon NN cord-015369-72cjogxz 6193 20 laceration laceration NN cord-015369-72cjogxz 6193 21 or or CC cord-015369-72cjogxz 6193 22 loss loss NN cord-015369-72cjogxz 6193 23 of of IN cord-015369-72cjogxz 6193 24 tissue tissue NN cord-015369-72cjogxz 6193 25 . . . cord-015369-72cjogxz 6194 1 The the DT cord-015369-72cjogxz 6194 2 incidence incidence NN cord-015369-72cjogxz 6194 3 of of IN cord-015369-72cjogxz 6194 4 dog dog NN cord-015369-72cjogxz 6194 5 - - HYPH cord-015369-72cjogxz 6194 6 bites bite NNS cord-015369-72cjogxz 6194 7 is be VBZ cord-015369-72cjogxz 6194 8 higher high JJR cord-015369-72cjogxz 6194 9 in in IN cord-015369-72cjogxz 6194 10 young young JJ cord-015369-72cjogxz 6194 11 children child NNS cord-015369-72cjogxz 6194 12 , , , cord-015369-72cjogxz 6194 13 involving involve VBG cord-015369-72cjogxz 6194 14 the the DT cord-015369-72cjogxz 6194 15 head head NN cord-015369-72cjogxz 6194 16 , , , cord-015369-72cjogxz 6194 17 face face NN cord-015369-72cjogxz 6194 18 or or CC cord-015369-72cjogxz 6194 19 neck neck NN cord-015369-72cjogxz 6194 20 . . . cord-015369-72cjogxz 6195 1 In in IN cord-015369-72cjogxz 6195 2 two two CD cord-015369-72cjogxz 6195 3 - - HYPH cord-015369-72cjogxz 6195 4 thirds third NNS cord-015369-72cjogxz 6195 5 of of IN cord-015369-72cjogxz 6195 6 cat cat NN cord-015369-72cjogxz 6195 7 bites bite VBZ cord-015369-72cjogxz 6195 8 the the DT cord-015369-72cjogxz 6195 9 upper upper JJ cord-015369-72cjogxz 6195 10 extremities extremity NNS cord-015369-72cjogxz 6195 11 were be VBD cord-015369-72cjogxz 6195 12 effected effect VBN cord-015369-72cjogxz 6195 13 , , , cord-015369-72cjogxz 6195 14 usually usually RB cord-015369-72cjogxz 6195 15 the the DT cord-015369-72cjogxz 6195 16 hands hand NNS cord-015369-72cjogxz 6195 17 and and CC cord-015369-72cjogxz 6195 18 fingers finger NNS cord-015369-72cjogxz 6195 19 . . . cord-015369-72cjogxz 6196 1 10 10 CD cord-015369-72cjogxz 6196 2 - - SYM cord-015369-72cjogxz 6196 3 50 50 CD cord-015369-72cjogxz 6196 4 % % NN cord-015369-72cjogxz 6196 5 of of IN cord-015369-72cjogxz 6196 6 human human JJ cord-015369-72cjogxz 6196 7 bite bite NN cord-015369-72cjogxz 6196 8 wounds wound NNS cord-015369-72cjogxz 6196 9 , , , cord-015369-72cjogxz 6196 10 concerning concern VBG cord-015369-72cjogxz 6196 11 the the DT cord-015369-72cjogxz 6196 12 middle middle JJ cord-015369-72cjogxz 6196 13 hand hand NN cord-015369-72cjogxz 6196 14 , , , cord-015369-72cjogxz 6196 15 resulted result VBD cord-015369-72cjogxz 6196 16 in in IN cord-015369-72cjogxz 6196 17 an an DT cord-015369-72cjogxz 6196 18 infection infection NN cord-015369-72cjogxz 6196 19 . . . cord-015369-72cjogxz 6197 1 Details detail NNS cord-015369-72cjogxz 6197 2 of of IN cord-015369-72cjogxz 6197 3 their -PRON- PRP$ cord-015369-72cjogxz 6197 4 injury injury NN cord-015369-72cjogxz 6197 5 treatment treatment NN cord-015369-72cjogxz 6197 6 and and CC cord-015369-72cjogxz 6197 7 outcome outcome NN cord-015369-72cjogxz 6197 8 were be VBD cord-015369-72cjogxz 6197 9 recorded record VBN cord-015369-72cjogxz 6197 10 . . . cord-015369-72cjogxz 6198 1 Results result NNS cord-015369-72cjogxz 6198 2 . . . cord-015369-72cjogxz 6199 1 There there EX cord-015369-72cjogxz 6199 2 were be VBD cord-015369-72cjogxz 6199 3 43 43 CD cord-015369-72cjogxz 6199 4 cases case NNS cord-015369-72cjogxz 6199 5 of of IN cord-015369-72cjogxz 6199 6 primary primary JJ cord-015369-72cjogxz 6199 7 infection infection NN cord-015369-72cjogxz 6199 8 within within IN cord-015369-72cjogxz 6199 9 12 12 CD cord-015369-72cjogxz 6199 10 h h NN cord-015369-72cjogxz 6199 11 after after IN cord-015369-72cjogxz 6199 12 the the DT cord-015369-72cjogxz 6199 13 bite bite NN cord-015369-72cjogxz 6199 14 injury injury NN cord-015369-72cjogxz 6199 15 and and CC cord-015369-72cjogxz 6199 16 103 103 CD cord-015369-72cjogxz 6199 17 cases case NNS cord-015369-72cjogxz 6199 18 of of IN cord-015369-72cjogxz 6199 19 delayed delay VBN cord-015369-72cjogxz 6199 20 infection infection NN cord-015369-72cjogxz 6199 21 ( ( -LRB- cord-015369-72cjogxz 6199 22 12 12 CD cord-015369-72cjogxz 6199 23 - - SYM cord-015369-72cjogxz 6199 24 72 72 CD cord-015369-72cjogxz 6199 25 h h NN cord-015369-72cjogxz 6199 26 after after IN cord-015369-72cjogxz 6199 27 bite bite NN cord-015369-72cjogxz 6199 28 injury injury NN cord-015369-72cjogxz 6199 29 ) ) -RRB- cord-015369-72cjogxz 6199 30 . . . cord-015369-72cjogxz 6200 1 Thirty thirty CD cord-015369-72cjogxz 6200 2 - - HYPH cord-015369-72cjogxz 6200 3 two two CD cord-015369-72cjogxz 6200 4 patients patient NNS cord-015369-72cjogxz 6200 5 required require VBD cord-015369-72cjogxz 6200 6 surgery surgery NN cord-015369-72cjogxz 6200 7 like like IN cord-015369-72cjogxz 6200 8 debridement debridement NN cord-015369-72cjogxz 6200 9 of of IN cord-015369-72cjogxz 6200 10 devitalized devitalized JJ cord-015369-72cjogxz 6200 11 tissue tissue NN cord-015369-72cjogxz 6200 12 to to TO cord-015369-72cjogxz 6200 13 minimize minimize VB cord-015369-72cjogxz 6200 14 the the DT cord-015369-72cjogxz 6200 15 wound wound NN cord-015369-72cjogxz 6200 16 infection infection NN cord-015369-72cjogxz 6200 17 after after IN cord-015369-72cjogxz 6200 18 thorough thorough JJ cord-015369-72cjogxz 6200 19 disinfection disinfection NN cord-015369-72cjogxz 6200 20 and and CC cord-015369-72cjogxz 6200 21 intravenous intravenous JJ cord-015369-72cjogxz 6200 22 antibiotic antibiotic JJ cord-015369-72cjogxz 6200 23 therapy therapy NN cord-015369-72cjogxz 6200 24 . . . cord-015369-72cjogxz 6201 1 Conclusions conclusion NNS cord-015369-72cjogxz 6201 2 . . . cord-015369-72cjogxz 6202 1 The the DT cord-015369-72cjogxz 6202 2 aim aim NN cord-015369-72cjogxz 6202 3 of of IN cord-015369-72cjogxz 6202 4 immediate immediate JJ cord-015369-72cjogxz 6202 5 surgical surgical JJ cord-015369-72cjogxz 6202 6 repair repair NN cord-015369-72cjogxz 6202 7 is be VBZ cord-015369-72cjogxz 6202 8 to to TO cord-015369-72cjogxz 6202 9 obtain obtain VB cord-015369-72cjogxz 6202 10 a a DT cord-015369-72cjogxz 6202 11 satisfactory satisfactory JJ cord-015369-72cjogxz 6202 12 cosmetic cosmetic JJ cord-015369-72cjogxz 6202 13 result result NN cord-015369-72cjogxz 6202 14 with with IN cord-015369-72cjogxz 6202 15 a a DT cord-015369-72cjogxz 6202 16 minimal minimal JJ cord-015369-72cjogxz 6202 17 risk risk NN cord-015369-72cjogxz 6202 18 of of IN cord-015369-72cjogxz 6202 19 wound wound NN cord-015369-72cjogxz 6202 20 infection infection NN cord-015369-72cjogxz 6202 21 . . . cord-015369-72cjogxz 6203 1 Antibiotic antibiotic JJ cord-015369-72cjogxz 6203 2 prophylaxis prophylaxis NN cord-015369-72cjogxz 6203 3 makes make VBZ cord-015369-72cjogxz 6203 4 sense sense NN cord-015369-72cjogxz 6203 5 in in IN cord-015369-72cjogxz 6203 6 immunsuprimized immunsuprimized JJ cord-015369-72cjogxz 6203 7 patients patient NNS cord-015369-72cjogxz 6203 8 , , , cord-015369-72cjogxz 6203 9 children child NNS cord-015369-72cjogxz 6203 10 up up IN cord-015369-72cjogxz 6203 11 to to TO cord-015369-72cjogxz 6203 12 two two CD cord-015369-72cjogxz 6203 13 years year NNS cord-015369-72cjogxz 6203 14 , , , cord-015369-72cjogxz 6203 15 bite bite NN cord-015369-72cjogxz 6203 16 injuries injury NNS cord-015369-72cjogxz 6203 17 of of IN cord-015369-72cjogxz 6203 18 the the DT cord-015369-72cjogxz 6203 19 head head NN cord-015369-72cjogxz 6203 20 , , , cord-015369-72cjogxz 6203 21 face face NN cord-015369-72cjogxz 6203 22 , , , cord-015369-72cjogxz 6203 23 hands hand NNS cord-015369-72cjogxz 6203 24 and and CC cord-015369-72cjogxz 6203 25 fingers finger NNS cord-015369-72cjogxz 6203 26 , , , cord-015369-72cjogxz 6203 27 and and CC cord-015369-72cjogxz 6203 28 feet foot NNS cord-015369-72cjogxz 6203 29 . . . cord-015369-72cjogxz 6204 1 Background background NN cord-015369-72cjogxz 6204 2 . . . cord-015369-72cjogxz 6205 1 We -PRON- PRP cord-015369-72cjogxz 6205 2 report report VBP cord-015369-72cjogxz 6205 3 on on IN cord-015369-72cjogxz 6205 4 three three CD cord-015369-72cjogxz 6205 5 diabetic diabetic JJ cord-015369-72cjogxz 6205 6 foot foot NN cord-015369-72cjogxz 6205 7 patients patient NNS cord-015369-72cjogxz 6205 8 suffering suffer VBG cord-015369-72cjogxz 6205 9 from from IN cord-015369-72cjogxz 6205 10 verrucous verrucous JJ cord-015369-72cjogxz 6205 11 skin skin NN cord-015369-72cjogxz 6205 12 lesions lesion NNS cord-015369-72cjogxz 6205 13 . . . cord-015369-72cjogxz 6206 1 All all DT cord-015369-72cjogxz 6206 2 patients patient NNS cord-015369-72cjogxz 6206 3 were be VBD cord-015369-72cjogxz 6206 4 suffering suffer VBG cord-015369-72cjogxz 6206 5 from from IN cord-015369-72cjogxz 6206 6 neuropathy neuropathy NN cord-015369-72cjogxz 6206 7 and and CC cord-015369-72cjogxz 6206 8 other other JJ cord-015369-72cjogxz 6206 9 complications complication NNS cord-015369-72cjogxz 6206 10 . . . cord-015369-72cjogxz 6207 1 In in IN cord-015369-72cjogxz 6207 2 two two CD cord-015369-72cjogxz 6207 3 patients patient NNS cord-015369-72cjogxz 6207 4 partial partial JJ cord-015369-72cjogxz 6207 5 forefoot forefoot NN cord-015369-72cjogxz 6207 6 amputation amputation NN cord-015369-72cjogxz 6207 7 had have VBD cord-015369-72cjogxz 6207 8 been be VBN cord-015369-72cjogxz 6207 9 performed perform VBN cord-015369-72cjogxz 6207 10 before before RB cord-015369-72cjogxz 6207 11 , , , cord-015369-72cjogxz 6207 12 followed follow VBN cord-015369-72cjogxz 6207 13 by by IN cord-015369-72cjogxz 6207 14 split split NN cord-015369-72cjogxz 6207 15 thickness thickness NN cord-015369-72cjogxz 6207 16 skin skin NN cord-015369-72cjogxz 6207 17 grafting grafting NN cord-015369-72cjogxz 6207 18 . . . cord-015369-72cjogxz 6208 1 One one CD cord-015369-72cjogxz 6208 2 patient patient NN cord-015369-72cjogxz 6208 3 developed develop VBD cord-015369-72cjogxz 6208 4 atypical atypical JJ cord-015369-72cjogxz 6208 5 malum malum NN cord-015369-72cjogxz 6208 6 perforans perforan NNS cord-015369-72cjogxz 6208 7 with with IN cord-015369-72cjogxz 6208 8 verrucous verrucous NNP cord-015369-72cjogxz 6208 9 surface surface NN cord-015369-72cjogxz 6208 10 with with IN cord-015369-72cjogxz 6208 11 a a DT cord-015369-72cjogxz 6208 12 pea pea NN cord-015369-72cjogxz 6208 13 - - HYPH cord-015369-72cjogxz 6208 14 sized sized JJ cord-015369-72cjogxz 6208 15 ulcer ulcer NN cord-015369-72cjogxz 6208 16 embedded embed VBN cord-015369-72cjogxz 6208 17 in in IN cord-015369-72cjogxz 6208 18 macerated macerated JJ cord-015369-72cjogxz 6208 19 horny horny JJ cord-015369-72cjogxz 6208 20 material material NN cord-015369-72cjogxz 6208 21 over over IN cord-015369-72cjogxz 6208 22 the the DT cord-015369-72cjogxz 6208 23 first first JJ cord-015369-72cjogxz 6208 24 metatarsal metatarsal NN cord-015369-72cjogxz 6208 25 head head NN cord-015369-72cjogxz 6208 26 . . . cord-015369-72cjogxz 6209 1 Methods method NNS cord-015369-72cjogxz 6209 2 . . . cord-015369-72cjogxz 6210 1 In in IN cord-015369-72cjogxz 6210 2 all all DT cord-015369-72cjogxz 6210 3 three three CD cord-015369-72cjogxz 6210 4 patients patient NNS cord-015369-72cjogxz 6210 5 verrucous verrucous JJ cord-015369-72cjogxz 6210 6 carcinoma carcinoma NN cord-015369-72cjogxz 6210 7 of of IN cord-015369-72cjogxz 6210 8 the the DT cord-015369-72cjogxz 6210 9 skin skin NN cord-015369-72cjogxz 6210 10 was be VBD cord-015369-72cjogxz 6210 11 suspected suspect VBN cord-015369-72cjogxz 6210 12 . . . cord-015369-72cjogxz 6211 1 Clinical clinical JJ cord-015369-72cjogxz 6211 2 findings finding NNS cord-015369-72cjogxz 6211 3 showed show VBD cord-015369-72cjogxz 6211 4 slowly slowly RB cord-015369-72cjogxz 6211 5 developing develop VBG cord-015369-72cjogxz 6211 6 cauliflower cauliflower NN cord-015369-72cjogxz 6211 7 - - HYPH cord-015369-72cjogxz 6211 8 like like JJ cord-015369-72cjogxz 6211 9 warty warty JJ cord-015369-72cjogxz 6211 10 tumours tumour NNS cord-015369-72cjogxz 6211 11 with with IN cord-015369-72cjogxz 6211 12 deep deep JJ cord-015369-72cjogxz 6211 13 sinuses sinus NNS cord-015369-72cjogxz 6211 14 and and CC cord-015369-72cjogxz 6211 15 foul foul JJ cord-015369-72cjogxz 6211 16 smelling smell VBG cord-015369-72cjogxz 6211 17 thick thick JJ cord-015369-72cjogxz 6211 18 greasy greasy JJ cord-015369-72cjogxz 6211 19 material material NN cord-015369-72cjogxz 6211 20 . . . cord-015369-72cjogxz 6212 1 Punch punch NN cord-015369-72cjogxz 6212 2 biopsies biopsy NNS cord-015369-72cjogxz 6212 3 , , , cord-015369-72cjogxz 6212 4 respectively respectively RB cord-015369-72cjogxz 6212 5 histological histological JJ cord-015369-72cjogxz 6212 6 examination examination NN cord-015369-72cjogxz 6212 7 of of IN cord-015369-72cjogxz 6212 8 derided deride VBN cord-015369-72cjogxz 6212 9 tissue tissue NN cord-015369-72cjogxz 6212 10 were be VBD cord-015369-72cjogxz 6212 11 performed perform VBN cord-015369-72cjogxz 6212 12 . . . cord-015369-72cjogxz 6213 1 In in IN cord-015369-72cjogxz 6213 2 all all DT cord-015369-72cjogxz 6213 3 patients patient NNS cord-015369-72cjogxz 6213 4 histological histological JJ cord-015369-72cjogxz 6213 5 findings finding NNS cord-015369-72cjogxz 6213 6 showed show VBD cord-015369-72cjogxz 6213 7 verrucous verrucous JJ cord-015369-72cjogxz 6213 8 carcinoma carcinoma NN cord-015369-72cjogxz 6213 9 . . . cord-015369-72cjogxz 6214 1 Results result NNS cord-015369-72cjogxz 6214 2 . . . cord-015369-72cjogxz 6215 1 Two two CD cord-015369-72cjogxz 6215 2 patients patient NNS cord-015369-72cjogxz 6215 3 were be VBD cord-015369-72cjogxz 6215 4 simultaneously simultaneously RB cord-015369-72cjogxz 6215 5 suffering suffer VBG cord-015369-72cjogxz 6215 6 from from IN cord-015369-72cjogxz 6215 7 deep deep JJ cord-015369-72cjogxz 6215 8 neuropathic neuropathic JJ cord-015369-72cjogxz 6215 9 ulcers ulcer NNS cord-015369-72cjogxz 6215 10 and and CC cord-015369-72cjogxz 6215 11 underlying underlying JJ cord-015369-72cjogxz 6215 12 osteomyelitis osteomyelitis NN cord-015369-72cjogxz 6215 13 requiring require VBG cord-015369-72cjogxz 6215 14 surgical surgical JJ cord-015369-72cjogxz 6215 15 intervention intervention NN cord-015369-72cjogxz 6215 16 . . . cord-015369-72cjogxz 6216 1 Transmetatarsal Transmetatarsal NNP cord-015369-72cjogxz 6216 2 amputation amputation NN cord-015369-72cjogxz 6216 3 was be VBD cord-015369-72cjogxz 6216 4 performed perform VBN cord-015369-72cjogxz 6216 5 to to TO cord-015369-72cjogxz 6216 6 heal heal VB cord-015369-72cjogxz 6216 7 osteomyelitis osteomyelitis NN cord-015369-72cjogxz 6216 8 and and CC cord-015369-72cjogxz 6216 9 to to TO cord-015369-72cjogxz 6216 10 obtain obtain VB cord-015369-72cjogxz 6216 11 a a DT cord-015369-72cjogxz 6216 12 stable stable JJ cord-015369-72cjogxz 6216 13 weightbearing weightbearing NN cord-015369-72cjogxz 6216 14 foot foot NN cord-015369-72cjogxz 6216 15 stump stump NN cord-015369-72cjogxz 6216 16 . . . cord-015369-72cjogxz 6217 1 In in IN cord-015369-72cjogxz 6217 2 one one CD cord-015369-72cjogxz 6217 3 patient patient JJ cord-015369-72cjogxz 6217 4 deep deep JJ cord-015369-72cjogxz 6217 5 ulcer ulcer NN cord-015369-72cjogxz 6217 6 debridement debridement NN cord-015369-72cjogxz 6217 7 was be VBD cord-015369-72cjogxz 6217 8 performed perform VBN cord-015369-72cjogxz 6217 9 followed follow VBN cord-015369-72cjogxz 6217 10 by by IN cord-015369-72cjogxz 6217 11 offloading offload VBG cord-015369-72cjogxz 6217 12 . . . cord-015369-72cjogxz 6218 1 Healing healing NN cord-015369-72cjogxz 6218 2 was be VBD cord-015369-72cjogxz 6218 3 achieved achieve VBN cord-015369-72cjogxz 6218 4 in in IN cord-015369-72cjogxz 6218 5 all all DT cord-015369-72cjogxz 6218 6 patients patient NNS cord-015369-72cjogxz 6218 7 . . . cord-015369-72cjogxz 6219 1 Final final JJ cord-015369-72cjogxz 6219 2 histological histological JJ cord-015369-72cjogxz 6219 3 findings finding NNS cord-015369-72cjogxz 6219 4 showed show VBD cord-015369-72cjogxz 6219 5 pseudoepitheliomatous pseudoepitheliomatous JJ cord-015369-72cjogxz 6219 6 hyperplasia hyperplasia NN cord-015369-72cjogxz 6219 7 with with IN cord-015369-72cjogxz 6219 8 focal focal JJ cord-015369-72cjogxz 6219 9 papillomatosis papillomatosis NN cord-015369-72cjogxz 6219 10 according accord VBG cord-015369-72cjogxz 6219 11 to to IN cord-015369-72cjogxz 6219 12 papillomatosis papillomatosis NNP cord-015369-72cjogxz 6219 13 cutis cutis NNP cord-015369-72cjogxz 6219 14 carcinoides carcinoides NNP cord-015369-72cjogxz 6219 15 , , , cord-015369-72cjogxz 6219 16 in in IN cord-015369-72cjogxz 6219 17 case case NN cord-015369-72cjogxz 6219 18 of of IN cord-015369-72cjogxz 6219 19 diabetic diabetic JJ cord-015369-72cjogxz 6219 20 neuropathy neuropathy NN cord-015369-72cjogxz 6219 21 called call VBN cord-015369-72cjogxz 6219 22 VSLDN VSLDN NNP cord-015369-72cjogxz 6219 23 ( ( -LRB- cord-015369-72cjogxz 6219 24 verrucous verrucous JJ cord-015369-72cjogxz 6219 25 skin skin NN cord-015369-72cjogxz 6219 26 like like IN cord-015369-72cjogxz 6219 27 lesions lesion NNS cord-015369-72cjogxz 6219 28 in in IN cord-015369-72cjogxz 6219 29 diabetic diabetic JJ cord-015369-72cjogxz 6219 30 neuropathy neuropathy NN cord-015369-72cjogxz 6219 31 ) ) -RRB- cord-015369-72cjogxz 6219 32 . . . cord-015369-72cjogxz 6220 1 Conclusions conclusion NNS cord-015369-72cjogxz 6220 2 . . . cord-015369-72cjogxz 6221 1 VSLDN VSLDN NNP cord-015369-72cjogxz 6221 2 and and CC cord-015369-72cjogxz 6221 3 diabetic diabetic JJ cord-015369-72cjogxz 6221 4 foot foot NN cord-015369-72cjogxz 6221 5 ulcers ulcer NNS cord-015369-72cjogxz 6221 6 are be VBP cord-015369-72cjogxz 6221 7 closely closely RB cord-015369-72cjogxz 6221 8 related relate VBN cord-015369-72cjogxz 6221 9 in in IN cord-015369-72cjogxz 6221 10 their -PRON- PRP$ cord-015369-72cjogxz 6221 11 aetiology aetiology NN cord-015369-72cjogxz 6221 12 and and CC cord-015369-72cjogxz 6221 13 pathogenesis pathogenesis NN cord-015369-72cjogxz 6221 14 , , , cord-015369-72cjogxz 6221 15 whereas whereas IN cord-015369-72cjogxz 6221 16 therapeutic therapeutic JJ cord-015369-72cjogxz 6221 17 strategy strategy NN cord-015369-72cjogxz 6221 18 has have VBZ cord-015369-72cjogxz 6221 19 not not RB cord-015369-72cjogxz 6221 20 yet yet RB cord-015369-72cjogxz 6221 21 been be VBN cord-015369-72cjogxz 6221 22 established establish VBN cord-015369-72cjogxz 6221 23 . . . cord-015369-72cjogxz 6222 1 In in IN cord-015369-72cjogxz 6222 2 case case NN cord-015369-72cjogxz 6222 3 of of IN cord-015369-72cjogxz 6222 4 accompanying accompany VBG cord-015369-72cjogxz 6222 5 osteomyelitis osteomyelitis NN cord-015369-72cjogxz 6222 6 required require VBD cord-015369-72cjogxz 6222 7 surgical surgical JJ cord-015369-72cjogxz 6222 8 procedure procedure NN cord-015369-72cjogxz 6222 9 enables enable VBZ cord-015369-72cjogxz 6222 10 histological histological JJ cord-015369-72cjogxz 6222 11 exclusion exclusion NN cord-015369-72cjogxz 6222 12 of of IN cord-015369-72cjogxz 6222 13 verrucous verrucous JJ cord-015369-72cjogxz 6222 14 carcinoma carcinoma NN cord-015369-72cjogxz 6222 15 . . . cord-015369-72cjogxz 6223 1 In in IN cord-015369-72cjogxz 6223 2 case case NN cord-015369-72cjogxz 6223 3 of of IN cord-015369-72cjogxz 6223 4 lacking lack VBG cord-015369-72cjogxz 6223 5 surgical surgical JJ cord-015369-72cjogxz 6223 6 indication indication NN cord-015369-72cjogxz 6223 7 , , , cord-015369-72cjogxz 6223 8 offloading offloading NN cord-015369-72cjogxz 6223 9 , , , cord-015369-72cjogxz 6223 10 professional professional JJ cord-015369-72cjogxz 6223 11 foot foot NN cord-015369-72cjogxz 6223 12 care care NN cord-015369-72cjogxz 6223 13 and and CC cord-015369-72cjogxz 6223 14 compression compression NN cord-015369-72cjogxz 6223 15 to to TO cord-015369-72cjogxz 6223 16 avoid avoid VB cord-015369-72cjogxz 6223 17 friction friction NN cord-015369-72cjogxz 6223 18 is be VBZ cord-015369-72cjogxz 6223 19 the the DT cord-015369-72cjogxz 6223 20 main main JJ cord-015369-72cjogxz 6223 21 strategy strategy NN cord-015369-72cjogxz 6223 22 for for IN cord-015369-72cjogxz 6223 23 therapy therapy NN cord-015369-72cjogxz 6223 24 and and CC cord-015369-72cjogxz 6223 25 prevention prevention NN cord-015369-72cjogxz 6223 26 of of IN cord-015369-72cjogxz 6223 27 VSLDN VSLDN NNP cord-015369-72cjogxz 6223 28 . . . cord-015369-72cjogxz 6224 1 Survived survive VBN cord-015369-72cjogxz 6224 2 suicide suicide NN cord-015369-72cjogxz 6224 3 shooting shoot VBG cord-015369-72cjogxz 6224 4 through through IN cord-015369-72cjogxz 6224 5 the the DT cord-015369-72cjogxz 6224 6 cavities cavity NNS cord-015369-72cjogxz 6224 7 of of IN cord-015369-72cjogxz 6224 8 pleura pleura NN cord-015369-72cjogxz 6224 9 , , , cord-015369-72cjogxz 6224 10 pericard pericard NN cord-015369-72cjogxz 6224 11 and and CC cord-015369-72cjogxz 6224 12 peritoneum peritoneum NNP cord-015369-72cjogxz 6224 13 auch auch NNP cord-015369-72cjogxz 6224 14 wenn wenn NNP cord-015369-72cjogxz 6224 15 die die VBP cord-015369-72cjogxz 6224 16 retrograde retrograde JJ cord-015369-72cjogxz 6225 1 Kontrastfüllung Kontrastfüllung NNP cord-015369-72cjogxz 6225 2 i -PRON- PRP cord-015369-72cjogxz 6225 3 m be VBP cord-015369-72cjogxz 6225 4 CT CT NNP cord-015369-72cjogxz 6225 5 nicht nicht NNP cord-015369-72cjogxz 6225 6 diagnostisch diagnostisch NNP cord-015369-72cjogxz 6225 7 ist ist NNP cord-015369-72cjogxz 6225 8 ! ! . cord-015369-72cjogxz 6226 1 Die die VB cord-015369-72cjogxz 6226 2 Laparoskopie Laparoskopie NNP cord-015369-72cjogxz 6226 3 bietet bietet NNP cord-015369-72cjogxz 6226 4 sich sich NNP cord-015369-72cjogxz 6226 5 sowohl sowohl NNP cord-015369-72cjogxz 6226 6 diagnostisch diagnostisch NNP cord-015369-72cjogxz 6227 1 wie wie NNP cord-015369-72cjogxz 6227 2 therapeutisch therapeutisch NNP cord-015369-72cjogxz 6228 1 an an DT cord-015369-72cjogxz 6229 1 und und IN cord-015369-72cjogxz 6229 2 ist ist NNP cord-015369-72cjogxz 6229 3 möglicherweise möglicherweise NNP cord-015369-72cjogxz 6229 4 dem dem NNP cord-015369-72cjogxz 6229 5 offenen offenen NNP cord-015369-72cjogxz 6229 6 Verfahren Verfahren NNP cord-015369-72cjogxz 6229 7 vorzuziehen vorzuziehen NNP cord-015369-72cjogxz 6229 8 . . . cord-015369-72cjogxz 6230 1 Außergewöhnlicher Außergewöhnlicher NNP cord-015369-72cjogxz 6230 2 Fall Fall NNP cord-015369-72cjogxz 6230 3 eines eine NNS cord-015369-72cjogxz 6231 1 Dermatofibrosarcoma Dermatofibrosarcoma NNP cord-015369-72cjogxz 6231 2 protuberans protuberan NNS cord-015369-72cjogxz 6232 1 -Ein -Ein NFP cord-015369-72cjogxz 6232 2 Fallbeispiel Fallbeispiel NNP cord-015369-72cjogxz 6232 3 mit mit VBD cord-015369-72cjogxz 6232 4 Literaturübersicht Literaturübersicht NNP cord-015369-72cjogxz 6232 5 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6232 6 . . . cord-015369-72cjogxz 6233 1 Das Das NNP cord-015369-72cjogxz 6233 2 Dermatofibrosarcoma Dermatofibrosarcoma NNP cord-015369-72cjogxz 6233 3 protuberans protuberan NNS cord-015369-72cjogxz 6233 4 ( ( -LRB- cord-015369-72cjogxz 6233 5 DFSP DFSP NNP cord-015369-72cjogxz 6233 6 ) ) -RRB- cord-015369-72cjogxz 6234 1 ist ist NNP cord-015369-72cjogxz 6234 2 ein ein NNP cord-015369-72cjogxz 6234 3 mesenchymaler mesenchymaler NNP cord-015369-72cjogxz 6234 4 maligner maligner NNP cord-015369-72cjogxz 6234 5 Tumor Tumor NNP cord-015369-72cjogxz 6234 6 , , , cord-015369-72cjogxz 6234 7 der der NNP cord-015369-72cjogxz 6234 8 nur nur NNP cord-015369-72cjogxz 6234 9 selten selten NNP cord-015369-72cjogxz 6234 10 metastasiert metastasiert NNP cord-015369-72cjogxz 6235 1 und und NNP cord-015369-72cjogxz 6235 2 durch durch NNP cord-015369-72cjogxz 6235 3 eine eine NNP cord-015369-72cjogxz 6235 4 oftmals oftmal NNS cord-015369-72cjogxz 6235 5 späte späte JJ cord-015369-72cjogxz 6235 6 Diagnosestellung Diagnosestellung NNP cord-015369-72cjogxz 6236 1 und und NNP cord-015369-72cjogxz 6237 1 langsam langsam NNP cord-015369-72cjogxz 6237 2 infiltrativem infiltrativem NNP cord-015369-72cjogxz 6237 3 Wachstum Wachstum NNP cord-015369-72cjogxz 6237 4 gekennzeichnet gekennzeichnet NN cord-015369-72cjogxz 6237 5 ist ist NN cord-015369-72cjogxz 6237 6 . . . cord-015369-72cjogxz 6238 1 Die die VB cord-015369-72cjogxz 6238 2 Resektion Resektion NNP cord-015369-72cjogxz 6238 3 mit mit NNP cord-015369-72cjogxz 6238 4 einem einem NNP cord-015369-72cjogxz 6238 5 ungenü ungenü NNP cord-015369-72cjogxz 6238 6 genden genden NNP cord-015369-72cjogxz 6238 7 Sicherheitsabstand Sicherheitsabstand NNP cord-015369-72cjogxz 6238 8 resultiert resultiert NN cord-015369-72cjogxz 6238 9 in in IN cord-015369-72cjogxz 6238 10 einem einem NNP cord-015369-72cjogxz 6238 11 Lokalrezidiv Lokalrezidiv NNP cord-015369-72cjogxz 6238 12 . . . cord-015369-72cjogxz 6239 1 Berichte Berichte NNP cord-015369-72cjogxz 6239 2 ü ü . cord-015369-72cjogxz 6240 1 ber ber NNP cord-015369-72cjogxz 6241 1 DFSP DFSP NNP cord-015369-72cjogxz 6242 1 sind sind NNP cord-015369-72cjogxz 6242 2 selten selten NNP cord-015369-72cjogxz 6242 3 aufgrund aufgrund NNP cord-015369-72cjogxz 6242 4 der der NNP cord-015369-72cjogxz 6242 5 geringen geringen NNP cord-015369-72cjogxz 6243 1 Inzidenz Inzidenz NNP cord-015369-72cjogxz 6243 2 von von NNP cord-015369-72cjogxz 6244 1 weniger weniger NNP cord-015369-72cjogxz 6244 2 als als NNP cord-015369-72cjogxz 6244 3 0.1 0.1 CD cord-015369-72cjogxz 6244 4 % % NN cord-015369-72cjogxz 6244 5 aller aller NNP cord-015369-72cjogxz 6244 6 Malignome Malignome NNP cord-015369-72cjogxz 6244 7 . . . cord-015369-72cjogxz 6245 1 In in IN cord-015369-72cjogxz 6245 2 der der NN cord-015369-72cjogxz 6245 3 vorliegenden vorliegenden VBN cord-015369-72cjogxz 6245 4 Arbeit Arbeit NNP cord-015369-72cjogxz 6245 5 wird wird NNP cord-015369-72cjogxz 6245 6 die die VBP cord-015369-72cjogxz 6245 7 Bedeutung Bedeutung NNP cord-015369-72cjogxz 6245 8 eines eines NNP cord-015369-72cjogxz 6246 1 ausreichenden ausreichenden NNP cord-015369-72cjogxz 6247 1 Sicherheitsabstands sicherheitsabstand NNS cord-015369-72cjogxz 6248 1 zur zur NNP cord-015369-72cjogxz 6249 1 Vermeidung Vermeidung NNP cord-015369-72cjogxz 6249 2 eines eines NNP cord-015369-72cjogxz 6250 1 Lokalrezidivs Lokalrezidivs NNP cord-015369-72cjogxz 6250 2 aufgezeigt aufgezeigt NNP cord-015369-72cjogxz 6250 3 . . . cord-015369-72cjogxz 6251 1 Methodik Methodik NNP cord-015369-72cjogxz 6251 2 . . . cord-015369-72cjogxz 6252 1 Ein Ein NNP cord-015369-72cjogxz 6252 2 36-jähriger 36-jähriger CD cord-015369-72cjogxz 6252 3 Patient Patient NNP cord-015369-72cjogxz 6252 4 stellte stellte NNP cord-015369-72cjogxz 6252 5 sich sich NNP cord-015369-72cjogxz 6252 6 mit mit NNP cord-015369-72cjogxz 6252 7 einem einem NNP cord-015369-72cjogxz 6252 8 an an DT cord-015369-72cjogxz 6252 9 Grösse Grösse NNP cord-015369-72cjogxz 6252 10 zunehmenden zunehmenden NNP cord-015369-72cjogxz 6252 11 Knoten Knoten NNP cord-015369-72cjogxz 6252 12 medial medial JJ cord-015369-72cjogxz 6252 13 des des FW cord-015369-72cjogxz 6252 14 linken linken FW cord-015369-72cjogxz 6252 15 Schulterblattes Schulterblattes NNP cord-015369-72cjogxz 6252 16 vor vor NNP cord-015369-72cjogxz 6252 17 . . . cord-015369-72cjogxz 6253 1 Klinisch Klinisch NNP cord-015369-72cjogxz 6253 2 zeigte zeigte NNP cord-015369-72cjogxz 6253 3 sich sich NNP cord-015369-72cjogxz 6253 4 ein ein NNP cord-015369-72cjogxz 6253 5 6 6 CD cord-015369-72cjogxz 6253 6 Â â NN cord-015369-72cjogxz 6253 7 8 8 CD cord-015369-72cjogxz 6253 8 cm cm NNS cord-015369-72cjogxz 6253 9 großer großer NNP cord-015369-72cjogxz 6253 10 , , , cord-015369-72cjogxz 6253 11 derber derber NNP cord-015369-72cjogxz 6253 12 , , , cord-015369-72cjogxz 6254 1 subkutan subkutan NNP cord-015369-72cjogxz 6254 2 liegender liegender NNP cord-015369-72cjogxz 6254 3 Knoten Knoten NNP cord-015369-72cjogxz 6254 4 , , , cord-015369-72cjogxz 6254 5 der der NN cord-015369-72cjogxz 6254 6 gut gut NN cord-015369-72cjogxz 6254 7 verschieblich verschieblich NNP cord-015369-72cjogxz 6254 8 , , , cord-015369-72cjogxz 6254 9 leicht leicht NNP cord-015369-72cjogxz 6254 10 überwärmt überwärmt NNP cord-015369-72cjogxz 6254 11 und und IN cord-015369-72cjogxz 6254 12 hämangiom hämangiom RB cord-015369-72cjogxz 6254 13 - - HYPH cord-015369-72cjogxz 6254 14 artig artig JJ cord-015369-72cjogxz 6254 15 imponierte imponierte NNS cord-015369-72cjogxz 6254 16 . . . cord-015369-72cjogxz 6255 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6255 2 . . . cord-015369-72cjogxz 6256 1 Die die VB cord-015369-72cjogxz 6256 2 klinischen klinischen NNP cord-015369-72cjogxz 6256 3 Befunde Befunde NNP cord-015369-72cjogxz 6256 4 ergaben ergaben NN cord-015369-72cjogxz 6256 5 den den NNP cord-015369-72cjogxz 6256 6 Verdacht Verdacht NNP cord-015369-72cjogxz 6256 7 auf auf NNP cord-015369-72cjogxz 6256 8 ein ein NNP cord-015369-72cjogxz 6256 9 Atherom Atherom NNP cord-015369-72cjogxz 6256 10 . . . cord-015369-72cjogxz 6257 1 Daraufhin Daraufhin NNP cord-015369-72cjogxz 6257 2 erfolgte erfolgte NN cord-015369-72cjogxz 6257 3 eine eine NN cord-015369-72cjogxz 6257 4 spindelförmige spindelförmige FW cord-015369-72cjogxz 6257 5 Exzision Exzision NNP cord-015369-72cjogxz 6257 6 . . . cord-015369-72cjogxz 6258 1 Intraoperativ intraoperativ JJ cord-015369-72cjogxz 6258 2 präsentierte präsentierte NN cord-015369-72cjogxz 6258 3 sich sich NNP cord-015369-72cjogxz 6259 1 ein ein NNP cord-015369-72cjogxz 6259 2 kugelig kugelig NNP cord-015369-72cjogxz 6259 3 - - HYPH cord-015369-72cjogxz 6259 4 glattes glattes NNP cord-015369-72cjogxz 6259 5 , , , cord-015369-72cjogxz 6259 6 prall prall NNP cord-015369-72cjogxz 6259 7 - - HYPH cord-015369-72cjogxz 6259 8 elastisches elastische NNS cord-015369-72cjogxz 6259 9 , , , cord-015369-72cjogxz 6260 1 gräuliches gräuliches NNP cord-015369-72cjogxz 6260 2 und und XX cord-015369-72cjogxz 6261 1 hämorrhagisches hämorrhagisches NNP cord-015369-72cjogxz 6261 2 Gebilde Gebilde NNP cord-015369-72cjogxz 6261 3 . . . cord-015369-72cjogxz 6262 1 Auf Auf NNP cord-015369-72cjogxz 6262 2 Grund Grund NNP cord-015369-72cjogxz 6262 3 der der NNP cord-015369-72cjogxz 6262 4 für für NNP cord-015369-72cjogxz 6263 1 ein ein NNP cord-015369-72cjogxz 6263 2 Atherom Atherom NNP cord-015369-72cjogxz 6264 1 untypischen untypischen NNP cord-015369-72cjogxz 6265 1 Befunde Befunde NNP cord-015369-72cjogxz 6265 2 wurde wurde VBD cord-015369-72cjogxz 6265 3 eine eine NNP cord-015369-72cjogxz 6265 4 histologische histologische NNP cord-015369-72cjogxz 6265 5 Untersuchung Untersuchung NNP cord-015369-72cjogxz 6265 6 veranlasst veranlasst NNP cord-015369-72cjogxz 6265 7 . . . cord-015369-72cjogxz 6266 1 Diese Diese NNP cord-015369-72cjogxz 6266 2 zeigte zeigte NNP cord-015369-72cjogxz 6266 3 ein ein NNP cord-015369-72cjogxz 6266 4 unvollständig unvollständig NNP cord-015369-72cjogxz 6266 5 exzidiertes exzidiertes NNP cord-015369-72cjogxz 6266 6 DFSP DFSP NNP cord-015369-72cjogxz 6266 7 . . . cord-015369-72cjogxz 6267 1 Es Es NNP cord-015369-72cjogxz 6267 2 erfolgte erfolgte NN cord-015369-72cjogxz 6267 3 die die VBP cord-015369-72cjogxz 6267 4 empfohlene empfohlene NN cord-015369-72cjogxz 6268 1 Nachresektion Nachresektion NNP cord-015369-72cjogxz 6268 2 mit mit NNP cord-015369-72cjogxz 6268 3 einem einem NNP cord-015369-72cjogxz 6268 4 Sicherheitsabstand Sicherheitsabstand NNP cord-015369-72cjogxz 6268 5 von von NNP cord-015369-72cjogxz 6268 6 2 2 CD cord-015369-72cjogxz 6268 7 cm cm NN cord-015369-72cjogxz 6268 8 mit mit NNP cord-015369-72cjogxz 6268 9 der der NNP cord-015369-72cjogxz 6268 10 histologischen histologischen NNP cord-015369-72cjogxz 6268 11 Dokumentation Dokumentation NNP cord-015369-72cjogxz 6268 12 der der NNP cord-015369-72cjogxz 6268 13 radikalen radikalen NNP cord-015369-72cjogxz 6268 14 Exzision Exzision NNP cord-015369-72cjogxz 6268 15 . . . cord-015369-72cjogxz 6269 1 I -PRON- PRP cord-015369-72cjogxz 6269 2 m be VBP cord-015369-72cjogxz 6269 3 bisherigen bisherigen NNP cord-015369-72cjogxz 6269 4 Verlauf Verlauf NNP cord-015369-72cjogxz 6269 5 keine keine NN cord-015369-72cjogxz 6269 6 Hinweise Hinweise NNP cord-015369-72cjogxz 6269 7 auf auf NNP cord-015369-72cjogxz 6269 8 ein ein NNP cord-015369-72cjogxz 6269 9 Lokalrezidiv Lokalrezidiv NNP cord-015369-72cjogxz 6269 10 . . . cord-015369-72cjogxz 6270 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6270 2 . . . cord-015369-72cjogxz 6271 1 Hinter Hinter NNP cord-015369-72cjogxz 6271 2 der der NNP cord-015369-72cjogxz 6271 3 Verdachtsdiagnose Verdachtsdiagnose NNP cord-015369-72cjogxz 6271 4 eines eine NNS cord-015369-72cjogxz 6272 1 Atheroms Atheroms NNP cord-015369-72cjogxz 6272 2 kann kann NNP cord-015369-72cjogxz 6272 3 sich sich NNP cord-015369-72cjogxz 6272 4 seltenerweise seltenerweise NNP cord-015369-72cjogxz 6272 5 ein ein NNP cord-015369-72cjogxz 6272 6 DFSP DFSP NNP cord-015369-72cjogxz 6272 7 verstecken verstecken NNP cord-015369-72cjogxz 6272 8 . . . cord-015369-72cjogxz 6273 1 Die die VB cord-015369-72cjogxz 6273 2 histologische histologische NN cord-015369-72cjogxz 6273 3 Untersuchung Untersuchung NNP cord-015369-72cjogxz 6273 4 eines eines NNP cord-015369-72cjogxz 6273 5 Resektates Resektates NNPS cord-015369-72cjogxz 6273 6 mit mit NNP cord-015369-72cjogxz 6273 7 , , , cord-015369-72cjogxz 6273 8 , , , cord-015369-72cjogxz 6273 9 auffälligem auffälligem FW cord-015369-72cjogxz 6273 10 ' ' '' cord-015369-72cjogxz 6273 11 ' ' '' cord-015369-72cjogxz 6274 1 Aspekt aspekt JJ cord-015369-72cjogxz 6274 2 ist ist NNP cord-015369-72cjogxz 6274 3 ein ein NN cord-015369-72cjogxz 6274 4 chirurgischer chirurgischer NN cord-015369-72cjogxz 6274 5 Grundsatz Grundsatz NNP cord-015369-72cjogxz 6274 6 . . . cord-015369-72cjogxz 6275 1 Nur nur UH cord-015369-72cjogxz 6276 1 so so RB cord-015369-72cjogxz 6276 2 kann kann NNP cord-015369-72cjogxz 6276 3 ein ein NNP cord-015369-72cjogxz 6276 4 rezidivfreies rezidivfreie VBZ cord-015369-72cjogxz 6276 5 Ü Ü NNP cord-015369-72cjogxz 6276 6 berleben berleben NN cord-015369-72cjogxz 6276 7 erreicht erreicht NNP cord-015369-72cjogxz 6276 8 werden werden NNP cord-015369-72cjogxz 6276 9 und und XX cord-015369-72cjogxz 6277 1 exzessive exzessive NNP cord-015369-72cjogxz 6277 2 Resektionen Resektionen NNP cord-015369-72cjogxz 6277 3 mit mit NNP cord-015369-72cjogxz 6277 4 plastisch plastisch NNP cord-015369-72cjogxz 6277 5 - - HYPH cord-015369-72cjogxz 6277 6 chirurgischer chirurgischer NNP cord-015369-72cjogxz 6278 1 Deckung Deckung NNP cord-015369-72cjogxz 6278 2 vermieden vermieden JJ cord-015369-72cjogxz 6278 3 werden werden NNP cord-015369-72cjogxz 6278 4 . . . cord-015369-72cjogxz 6279 1 Hydrogen hydrogen NN cord-015369-72cjogxz 6279 2 sulphide sulphide NN cord-015369-72cjogxz 6279 3 is be VBZ cord-015369-72cjogxz 6279 4 a a DT cord-015369-72cjogxz 6279 5 colourless colourless JJ cord-015369-72cjogxz 6279 6 , , , cord-015369-72cjogxz 6279 7 highly highly RB cord-015369-72cjogxz 6279 8 toxic toxic JJ cord-015369-72cjogxz 6279 9 , , , cord-015369-72cjogxz 6279 10 flammable flammable JJ cord-015369-72cjogxz 6279 11 and and CC cord-015369-72cjogxz 6279 12 mucosal mucosal JJ cord-015369-72cjogxz 6279 13 irritating irritating JJ cord-015369-72cjogxz 6279 14 gas gas NN cord-015369-72cjogxz 6279 15 which which WDT cord-015369-72cjogxz 6279 16 mainly mainly RB cord-015369-72cjogxz 6279 17 originates originate VBZ cord-015369-72cjogxz 6279 18 during during IN cord-015369-72cjogxz 6279 19 breakdown breakdown NN cord-015369-72cjogxz 6279 20 of of IN cord-015369-72cjogxz 6279 21 organic organic JJ cord-015369-72cjogxz 6279 22 matter matter NN cord-015369-72cjogxz 6279 23 in in IN cord-015369-72cjogxz 6279 24 the the DT cord-015369-72cjogxz 6279 25 absence absence NN cord-015369-72cjogxz 6279 26 of of IN cord-015369-72cjogxz 6279 27 oxygen oxygen NN cord-015369-72cjogxz 6279 28 . . . cord-015369-72cjogxz 6280 1 After after IN cord-015369-72cjogxz 6280 2 inhalation inhalation NN cord-015369-72cjogxz 6280 3 hydrogen hydrogen NN cord-015369-72cjogxz 6280 4 sulphide sulphide NN cord-015369-72cjogxz 6280 5 binds bind VBZ cord-015369-72cjogxz 6280 6 to to IN cord-015369-72cjogxz 6280 7 the the DT cord-015369-72cjogxz 6280 8 mitochondrial mitochondrial JJ cord-015369-72cjogxz 6280 9 respiratory respiratory JJ cord-015369-72cjogxz 6280 10 enzyme enzyme NN cord-015369-72cjogxz 6280 11 preventing prevent VBG cord-015369-72cjogxz 6280 12 oxydative oxydative JJ cord-015369-72cjogxz 6280 13 phosphorylation phosphorylation NN cord-015369-72cjogxz 6280 14 , , , cord-015369-72cjogxz 6280 15 thereby thereby RB cord-015369-72cjogxz 6280 16 causing cause VBG cord-015369-72cjogxz 6280 17 reversible reversible JJ cord-015369-72cjogxz 6280 18 inhibition inhibition NN cord-015369-72cjogxz 6280 19 of of IN cord-015369-72cjogxz 6280 20 aerobic aerobic JJ cord-015369-72cjogxz 6280 21 metabolism metabolism NN cord-015369-72cjogxz 6280 22 and and CC cord-015369-72cjogxz 6280 23 cellular cellular JJ cord-015369-72cjogxz 6280 24 anoxia anoxia NN cord-015369-72cjogxz 6280 25 . . . cord-015369-72cjogxz 6281 1 The the DT cord-015369-72cjogxz 6281 2 therapeutic therapeutic JJ cord-015369-72cjogxz 6281 3 use use NN cord-015369-72cjogxz 6281 4 of of IN cord-015369-72cjogxz 6281 5 hyperbaric hyperbaric NN cord-015369-72cjogxz 6281 6 oxygen oxygen NN cord-015369-72cjogxz 6281 7 for for IN cord-015369-72cjogxz 6281 8 hydrogen hydrogen NN cord-015369-72cjogxz 6281 9 sulphide sulphide NN cord-015369-72cjogxz 6281 10 intoxication intoxication NN cord-015369-72cjogxz 6281 11 is be VBZ cord-015369-72cjogxz 6281 12 not not RB cord-015369-72cjogxz 6281 13 standardised standardised JJ cord-015369-72cjogxz 6281 14 and and CC cord-015369-72cjogxz 6281 15 its -PRON- PRP$ cord-015369-72cjogxz 6281 16 use use NN cord-015369-72cjogxz 6281 17 is be VBZ cord-015369-72cjogxz 6281 18 still still RB cord-015369-72cjogxz 6281 19 controversial controversial JJ cord-015369-72cjogxz 6281 20 . . . cord-015369-72cjogxz 6282 1 21 21 CD cord-015369-72cjogxz 6282 2 victims victim NNS cord-015369-72cjogxz 6282 3 of of IN cord-015369-72cjogxz 6282 4 occupational occupational JJ cord-015369-72cjogxz 6282 5 hydrogen hydrogen NN cord-015369-72cjogxz 6282 6 sulphide sulphide NN cord-015369-72cjogxz 6282 7 intoxication intoxication NN cord-015369-72cjogxz 6282 8 were be VBD cord-015369-72cjogxz 6282 9 referred refer VBN cord-015369-72cjogxz 6282 10 to to IN cord-015369-72cjogxz 6282 11 our -PRON- PRP$ cord-015369-72cjogxz 6282 12 centre centre NN cord-015369-72cjogxz 6282 13 between between IN cord-015369-72cjogxz 6282 14 3/2006 3/2006 CD cord-015369-72cjogxz 6282 15 and and CC cord-015369-72cjogxz 6282 16 9/ 9/ CD cord-015369-72cjogxz 6282 17 2007 2007 CD cord-015369-72cjogxz 6282 18 . . . cord-015369-72cjogxz 6283 1 Before before IN cord-015369-72cjogxz 6283 2 admission admission NN cord-015369-72cjogxz 6283 3 , , , cord-015369-72cjogxz 6283 4 100 100 CD cord-015369-72cjogxz 6283 5 % % NN cord-015369-72cjogxz 6283 6 oxygen oxygen NN cord-015369-72cjogxz 6283 7 had have VBD cord-015369-72cjogxz 6283 8 been be VBN cord-015369-72cjogxz 6283 9 was be VBD cord-015369-72cjogxz 6283 10 given give VBN cord-015369-72cjogxz 6283 11 by by IN cord-015369-72cjogxz 6283 12 mask mask NN cord-015369-72cjogxz 6283 13 ( ( -LRB- cord-015369-72cjogxz 6283 14 n n NN cord-015369-72cjogxz 6283 15 ¼ ¼ NNP cord-015369-72cjogxz 6283 16 15 15 CD cord-015369-72cjogxz 6283 17 ) ) -RRB- cord-015369-72cjogxz 6283 18 or or CC cord-015369-72cjogxz 6283 19 by by IN cord-015369-72cjogxz 6283 20 endo endo JJ cord-015369-72cjogxz 6283 21 - - HYPH cord-015369-72cjogxz 6283 22 tracheal tracheal JJ cord-015369-72cjogxz 6283 23 tube tube NN cord-015369-72cjogxz 6283 24 ( ( -LRB- cord-015369-72cjogxz 6283 25 n n NN cord-015369-72cjogxz 6283 26 ¼ ¼ NNP cord-015369-72cjogxz 6283 27 6 6 CD cord-015369-72cjogxz 6283 28 ) ) -RRB- cord-015369-72cjogxz 6283 29 . . . cord-015369-72cjogxz 6284 1 Two two CD cord-015369-72cjogxz 6284 2 patients patient NNS cord-015369-72cjogxz 6284 3 had have VBD cord-015369-72cjogxz 6284 4 been be VBN cord-015369-72cjogxz 6284 5 resuscitated resuscitate VBN cord-015369-72cjogxz 6284 6 at at IN cord-015369-72cjogxz 6284 7 the the DT cord-015369-72cjogxz 6284 8 site site NN cord-015369-72cjogxz 6284 9 of of IN cord-015369-72cjogxz 6284 10 the the DT cord-015369-72cjogxz 6284 11 accident accident NN cord-015369-72cjogxz 6284 12 , , , cord-015369-72cjogxz 6284 13 in in IN cord-015369-72cjogxz 6284 14 the the DT cord-015369-72cjogxz 6284 15 six six CD cord-015369-72cjogxz 6284 16 severe severe JJ cord-015369-72cjogxz 6284 17 cases case NNS cord-015369-72cjogxz 6284 18 4-Dimethylaminophenol 4-dimethylaminophenol CD cord-015369-72cjogxz 6284 19 was be VBD cord-015369-72cjogxz 6284 20 administered administer VBN cord-015369-72cjogxz 6284 21 as as IN cord-015369-72cjogxz 6284 22 antidotal antidotal JJ cord-015369-72cjogxz 6284 23 therapy therapy NN cord-015369-72cjogxz 6284 24 . . . cord-015369-72cjogxz 6285 1 Hyperbaric hyperbaric NN cord-015369-72cjogxz 6285 2 oxygenation oxygenation NN cord-015369-72cjogxz 6285 3 was be VBD cord-015369-72cjogxz 6285 4 done do VBN cord-015369-72cjogxz 6285 5 immediately immediately RB cord-015369-72cjogxz 6285 6 after after IN cord-015369-72cjogxz 6285 7 admission admission NN cord-015369-72cjogxz 6285 8 in in IN cord-015369-72cjogxz 6285 9 all all DT cord-015369-72cjogxz 6285 10 21 21 CD cord-015369-72cjogxz 6285 11 patients patient NNS cord-015369-72cjogxz 6285 12 by by IN cord-015369-72cjogxz 6285 13 using use VBG cord-015369-72cjogxz 6285 14 the the DT cord-015369-72cjogxz 6285 15 schedule schedule NN cord-015369-72cjogxz 6285 16 otherwise otherwise RB cord-015369-72cjogxz 6285 17 applied apply VBD cord-015369-72cjogxz 6285 18 in in IN cord-015369-72cjogxz 6285 19 carbon carbon NN cord-015369-72cjogxz 6285 20 monoxide monoxide NN cord-015369-72cjogxz 6285 21 - - HYPH cord-015369-72cjogxz 6285 22 intoxication intoxication NN cord-015369-72cjogxz 6285 23 . . . cord-015369-72cjogxz 6286 1 2 2 CD cord-015369-72cjogxz 6286 2 out out IN cord-015369-72cjogxz 6286 3 of of IN cord-015369-72cjogxz 6286 4 21 21 CD cord-015369-72cjogxz 6286 5 patients patient NNS cord-015369-72cjogxz 6286 6 ( ( -LRB- cord-015369-72cjogxz 6286 7 9.5 9.5 CD cord-015369-72cjogxz 6286 8 % % NN cord-015369-72cjogxz 6286 9 ) ) -RRB- cord-015369-72cjogxz 6286 10 died die VBD cord-015369-72cjogxz 6286 11 of of IN cord-015369-72cjogxz 6286 12 irreversible irreversible JJ cord-015369-72cjogxz 6286 13 cerebral cerebral JJ cord-015369-72cjogxz 6286 14 ischemia ischemia NN cord-015369-72cjogxz 6286 15 or or CC cord-015369-72cjogxz 6286 16 pulmonary pulmonary JJ cord-015369-72cjogxz 6286 17 edema edema NN cord-015369-72cjogxz 6286 18 , , , cord-015369-72cjogxz 6286 19 respectively respectively RB cord-015369-72cjogxz 6286 20 . . . cord-015369-72cjogxz 6287 1 The the DT cord-015369-72cjogxz 6287 2 remaining remain VBG cord-015369-72cjogxz 6287 3 19 19 CD cord-015369-72cjogxz 6287 4 patients patient NNS cord-015369-72cjogxz 6287 5 recovered recover VBN cord-015369-72cjogxz 6287 6 without without IN cord-015369-72cjogxz 6287 7 any any DT cord-015369-72cjogxz 6287 8 neurological neurological JJ cord-015369-72cjogxz 6287 9 sequelae sequela NNS cord-015369-72cjogxz 6287 10 and and CC cord-015369-72cjogxz 6287 11 were be VBD cord-015369-72cjogxz 6287 12 discharged discharge VBN cord-015369-72cjogxz 6287 13 for for IN cord-015369-72cjogxz 6287 14 outpatient outpatient NN cord-015369-72cjogxz 6287 15 care care NN cord-015369-72cjogxz 6287 16 after after IN cord-015369-72cjogxz 6287 17 a a DT cord-015369-72cjogxz 6287 18 median median NN cord-015369-72cjogxz 6287 19 of of IN cord-015369-72cjogxz 6287 20 2.8 2.8 CD cord-015369-72cjogxz 6287 21 days day NNS cord-015369-72cjogxz 6287 22 ( ( -LRB- cord-015369-72cjogxz 6287 23 range range VBP cord-015369-72cjogxz 6287 24 1 1 CD cord-015369-72cjogxz 6287 25 - - SYM cord-015369-72cjogxz 6287 26 12 12 CD cord-015369-72cjogxz 6287 27 days day NNS cord-015369-72cjogxz 6287 28 ) ) -RRB- cord-015369-72cjogxz 6287 29 . . . cord-015369-72cjogxz 6288 1 No no DT cord-015369-72cjogxz 6288 2 antidote antidote NN cord-015369-72cjogxz 6288 3 - - HYPH cord-015369-72cjogxz 6288 4 related relate VBN cord-015369-72cjogxz 6288 5 adverse adverse JJ cord-015369-72cjogxz 6288 6 effects effect NNS cord-015369-72cjogxz 6288 7 were be VBD cord-015369-72cjogxz 6288 8 observed observe VBN cord-015369-72cjogxz 6288 9 . . . cord-015369-72cjogxz 6289 1 In in IN cord-015369-72cjogxz 6289 2 hydrogen hydrogen NN cord-015369-72cjogxz 6289 3 sulphide sulphide NN cord-015369-72cjogxz 6289 4 intoxication intoxication NN cord-015369-72cjogxz 6289 5 hyperbaric hyperbaric NN cord-015369-72cjogxz 6289 6 oxygenation oxygenation NN cord-015369-72cjogxz 6289 7 ensures ensure VBZ cord-015369-72cjogxz 6289 8 quick quick JJ cord-015369-72cjogxz 6289 9 re re NN cord-015369-72cjogxz 6289 10 - - NN cord-015369-72cjogxz 6289 11 oxygenation oxygenation NN cord-015369-72cjogxz 6289 12 and and CC cord-015369-72cjogxz 6289 13 counteracts counteract VBZ cord-015369-72cjogxz 6289 14 the the DT cord-015369-72cjogxz 6289 15 decrement decrement NN cord-015369-72cjogxz 6289 16 in in IN cord-015369-72cjogxz 6289 17 oxygen oxygen NN cord-015369-72cjogxz 6289 18 carriage carriage NN cord-015369-72cjogxz 6289 19 caused cause VBN cord-015369-72cjogxz 6289 20 by by IN cord-015369-72cjogxz 6289 21 methemoglobinemia methemoglobinemia NN cord-015369-72cjogxz 6289 22 due due IN cord-015369-72cjogxz 6289 23 to to IN cord-015369-72cjogxz 6289 24 antidoteadministration antidoteadministration NN cord-015369-72cjogxz 6289 25 . . . cord-015369-72cjogxz 6290 1 In in IN cord-015369-72cjogxz 6290 2 our -PRON- PRP$ cord-015369-72cjogxz 6290 3 experience experience NN cord-015369-72cjogxz 6290 4 , , , cord-015369-72cjogxz 6290 5 hyperbaric hyperbaric NN cord-015369-72cjogxz 6290 6 oxygenation oxygenation NN cord-015369-72cjogxz 6290 7 alone alone RB cord-015369-72cjogxz 6290 8 or or CC cord-015369-72cjogxz 6290 9 in in IN cord-015369-72cjogxz 6290 10 combination combination NN cord-015369-72cjogxz 6290 11 with with IN cord-015369-72cjogxz 6290 12 4-Dimethylaminophenol 4-dimethylaminophenol CD cord-015369-72cjogxz 6290 13 therapy therapy NN cord-015369-72cjogxz 6290 14 proved prove VBD cord-015369-72cjogxz 6290 15 a a DT cord-015369-72cjogxz 6290 16 safe safe JJ cord-015369-72cjogxz 6290 17 tool tool NN cord-015369-72cjogxz 6290 18 in in IN cord-015369-72cjogxz 6290 19 the the DT cord-015369-72cjogxz 6290 20 management management NN cord-015369-72cjogxz 6290 21 of of IN cord-015369-72cjogxz 6290 22 mild mild JJ cord-015369-72cjogxz 6290 23 or or CC cord-015369-72cjogxz 6290 24 severe severe JJ cord-015369-72cjogxz 6290 25 hydrogen hydrogen NN cord-015369-72cjogxz 6290 26 sulphide sulphide NN cord-015369-72cjogxz 6290 27 intoxication intoxication NN cord-015369-72cjogxz 6290 28 , , , cord-015369-72cjogxz 6290 29 respectively respectively RB cord-015369-72cjogxz 6290 30 . . . cord-015369-72cjogxz 6291 1 Influence influence NN cord-015369-72cjogxz 6291 2 of of IN cord-015369-72cjogxz 6291 3 a a DT cord-015369-72cjogxz 6291 4 new new JJ cord-015369-72cjogxz 6291 5 self self NN cord-015369-72cjogxz 6291 6 - - HYPH cord-015369-72cjogxz 6291 7 fixing fix VBG cord-015369-72cjogxz 6291 8 hernia hernia NN cord-015369-72cjogxz 6291 9 mesh mesh NN cord-015369-72cjogxz 6291 10 on on IN cord-015369-72cjogxz 6291 11 the the DT cord-015369-72cjogxz 6291 12 ductus ductus NN cord-015369-72cjogxz 6291 13 deferens deferen NNS cord-015369-72cjogxz 6291 14 in in IN cord-015369-72cjogxz 6291 15 the the DT cord-015369-72cjogxz 6291 16 rat rat NN cord-015369-72cjogxz 6291 17 model model NN cord-015369-72cjogxz 6291 18 _SP cord-015369-72cjogxz 6291 19 Inferior Inferior NNP cord-015369-72cjogxz 6291 20 vena vena FW cord-015369-72cjogxz 6291 21 cava cava NN cord-015369-72cjogxz 6291 22 - - HYPH cord-015369-72cjogxz 6291 23 associated associate VBN cord-015369-72cjogxz 6291 24 tumor tumor NN cord-015369-72cjogxz 6291 25 lesionschallenging lesionschallenge VBG cord-015369-72cjogxz 6291 26 vascularsurgical vascularsurgical JJ cord-015369-72cjogxz 6291 27 management management NN cord-015369-72cjogxz 6291 28 in in IN cord-015369-72cjogxz 6291 29 a a DT cord-015369-72cjogxz 6291 30 representative representative JJ cord-015369-72cjogxz 6291 31 case case NN cord-015369-72cjogxz 6291 32 series series NN cord-015369-72cjogxz 6291 33 of of IN cord-015369-72cjogxz 6291 34 14 14 CD cord-015369-72cjogxz 6291 35 patients patient NNS cord-015369-72cjogxz 6291 36 Methodik Methodik NNP cord-015369-72cjogxz 6291 37 . . . cord-015369-72cjogxz 6292 1 Anhand Anhand NNP cord-015369-72cjogxz 6292 2 einer einer NNP cord-015369-72cjogxz 6292 3 außergewöhnlichen außergewöhnlichen VBZ cord-015369-72cjogxz 6292 4 Kasuistik Kasuistik NNP cord-015369-72cjogxz 6292 5 wird wird NNP cord-015369-72cjogxz 6292 6 die die VBP cord-015369-72cjogxz 6292 7 seltene seltene JJ cord-015369-72cjogxz 6292 8 Konstellation Konstellation NNP cord-015369-72cjogxz 6292 9 eines eine NNS cord-015369-72cjogxz 6293 1 abdominalen abdominalen NNP cord-015369-72cjogxz 6293 2 fibromyxoiden fibromyxoiden NNP cord-015369-72cjogxz 6293 3 Sarkoms Sarkoms NNP cord-015369-72cjogxz 6293 4 mit mit NNP cord-015369-72cjogxz 6293 5 nicht nicht NNP cord-015369-72cjogxz 6293 6 vorbeschriebener vorbeschriebener NNP cord-015369-72cjogxz 6293 7 Manifestation Manifestation NNP cord-015369-72cjogxz 6293 8 i -PRON- PRP cord-015369-72cjogxz 6293 9 m be VBP cord-015369-72cjogxz 6293 10 greisen greisen NNP cord-015369-72cjogxz 6293 11 Lebensalter Lebensalter NNP cord-015369-72cjogxz 6293 12 , , , cord-015369-72cjogxz 6294 1 wesentliche wesentliche NNP cord-015369-72cjogxz 6294 2 Aspekte Aspekte NNP cord-015369-72cjogxz 6294 3 des des NNP cord-015369-72cjogxz 6295 1 perioperativen perioperativen NNP cord-015369-72cjogxz 6295 2 diagnostischen diagnostischen NNP cord-015369-72cjogxz 6296 1 und und IN cord-015369-72cjogxz 6296 2 therapeutischen therapeutischen NNP cord-015369-72cjogxz 6296 3 Managements management NNS cord-015369-72cjogxz 6296 4 dargestellt dargestellt NNP cord-015369-72cjogxz 6296 5 und und IN cord-015369-72cjogxz 6296 6 ins in NNS cord-015369-72cjogxz 6297 1 Verhältnis Verhältnis NNP cord-015369-72cjogxz 6297 2 zu zu NNP cord-015369-72cjogxz 6297 3 verfügbaren verfügbaren NNP cord-015369-72cjogxz 6297 4 Literaturangaben Literaturangaben NNP cord-015369-72cjogxz 6297 5 gesetzt gesetzt NN cord-015369-72cjogxz 6297 6 . . . cord-015369-72cjogxz 6298 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6298 2 . . . cord-015369-72cjogxz 6299 1 Eine Eine NNP cord-015369-72cjogxz 6299 2 88-jährige 88-jährige CD cord-015369-72cjogxz 6299 3 multimorbide multimorbide NN cord-015369-72cjogxz 6300 1 Patientin Patientin NNP cord-015369-72cjogxz 6300 2 fiel fiel NNP cord-015369-72cjogxz 6300 3 durch durch NNP cord-015369-72cjogxz 6300 4 erhebliche erhebliche NNP cord-015369-72cjogxz 6300 5 Obstipationneigung Obstipationneigung NNP cord-015369-72cjogxz 6300 6 mit mit NNP cord-015369-72cjogxz 6300 7 Subileus Subileus NNP cord-015369-72cjogxz 6300 8 auf auf NNP cord-015369-72cjogxz 6300 9 ( ( -LRB- cord-015369-72cjogxz 6300 10 Nebenerkrankungen Nebenerkrankungen NNP cord-015369-72cjogxz 6300 11 : : : cord-015369-72cjogxz 6300 12 Z.n Z.n NNP cord-015369-72cjogxz 6300 13 . . . cord-015369-72cjogxz 6301 1 Lungenembolie Lungenembolie NNP cord-015369-72cjogxz 6301 2 , , , cord-015369-72cjogxz 6301 3 Diabetes diabetes NN cord-015369-72cjogxz 6301 4 , , , cord-015369-72cjogxz 6301 5 KHK KHK NNP cord-015369-72cjogxz 6301 6 , , , cord-015369-72cjogxz 6301 7 Hypertonie Hypertonie NNP cord-015369-72cjogxz 6301 8 , , , cord-015369-72cjogxz 6301 9 beginnend beginnend NNP cord-015369-72cjogxz 6301 10 dekompensierende dekompensierende NNP cord-015369-72cjogxz 6301 11 chronische chronische NNP cord-015369-72cjogxz 6301 12 Niereninsuffizienz Niereninsuffizienz NNP cord-015369-72cjogxz 6301 13 ) ) -RRB- cord-015369-72cjogxz 6301 14 . . . cord-015369-72cjogxz 6302 1 Anamnestisch Anamnestisch NNP cord-015369-72cjogxz 6302 2 Z.n Z.n NNP cord-015369-72cjogxz 6302 3 . . . cord-015369-72cjogxz 6303 1 Punktion punktion NN cord-015369-72cjogxz 6303 2 unklarer unklarer NN cord-015369-72cjogxz 6303 3 Lebertumorläsion Lebertumorläsion NNP cord-015369-72cjogxz 6303 4 6 6 CD cord-015369-72cjogxz 6303 5 Jahre Jahre NNP cord-015369-72cjogxz 6303 6 zuvor zuvor NNP cord-015369-72cjogxz 6304 1 ( ( -LRB- cord-015369-72cjogxz 6304 2 Histologie Histologie NNP cord-015369-72cjogxz 6304 3 : : : cord-015369-72cjogxz 6304 4 sklerosiertes sklerosierte NNS cord-015369-72cjogxz 6304 5 Hämangiom)-klinisch hämangiom)-klinisch XX cord-015369-72cjogxz 6304 6 monströse monströse XX cord-015369-72cjogxz 6305 1 Resistenz Resistenz NNP cord-015369-72cjogxz 6305 2 i -PRON- PRP cord-015369-72cjogxz 6305 3 m be VBP cord-015369-72cjogxz 6305 4 Mittelbauch Mittelbauch NNP cord-015369-72cjogxz 6305 5 . . . cord-015369-72cjogxz 6306 1 Sonographie Sonographie NNP cord-015369-72cjogxz 6306 2 und und IN cord-015369-72cjogxz 6306 3 CT CT NNP cord-015369-72cjogxz 6306 4 : : : cord-015369-72cjogxz 6307 1 Monströse Monströse NNP cord-015369-72cjogxz 6307 2 teils teils NNP cord-015369-72cjogxz 6307 3 zystisch zystisch NNP cord-015369-72cjogxz 6307 4 , , , cord-015369-72cjogxz 6307 5 teils teils NNP cord-015369-72cjogxz 6307 6 mit mit NNP cord-015369-72cjogxz 6307 7 liquiden liquiden NNP cord-015369-72cjogxz 6307 8 Anteilen Anteilen NNP cord-015369-72cjogxz 6307 9 bzw bzw NNP cord-015369-72cjogxz 6307 10 . . . cord-015369-72cjogxz 6308 1 solide solide NNP cord-015369-72cjogxz 6308 2 imponierende imponierende NNP cord-015369-72cjogxz 6309 1 Tumorläsion Tumorläsion NNP cord-015369-72cjogxz 6309 2 zwischen zwischen NNP cord-015369-72cjogxz 6309 3 Leber Leber NNP cord-015369-72cjogxz 6309 4 und und IN cord-015369-72cjogxz 6309 5 Magen Magen NNP cord-015369-72cjogxz 6309 6 ohne ohne NNP cord-015369-72cjogxz 6309 7 Organzugehörigkeit Organzugehörigkeit NNP cord-015369-72cjogxz 6309 8 ; ; : cord-015369-72cjogxz 6310 1 angiographisch angiographisch NNP cord-015369-72cjogxz 6311 1 keine keine NNP cord-015369-72cjogxz 6311 2 pathologischen pathologischen NNP cord-015369-72cjogxz 6311 3 Tumorgefäße Tumorgefäße NNP cord-015369-72cjogxz 6311 4 ( ( -LRB- cord-015369-72cjogxz 6311 5 venöse venöse NNP cord-015369-72cjogxz 6311 6 Abflussbehinderung Abflussbehinderung NNP cord-015369-72cjogxz 6311 7 ) ) -RRB- cord-015369-72cjogxz 6311 8 . . . cord-015369-72cjogxz 6312 1 Die die VB cord-015369-72cjogxz 6312 2 transcutane transcutane NNP cord-015369-72cjogxz 6312 3 FNP FNP NNP cord-015369-72cjogxz 6312 4 erbrachte erbrachte NNS cord-015369-72cjogxz 6312 5 keine keine NNP cord-015369-72cjogxz 6312 6 Diagnosesicherung Diagnosesicherung NNP cord-015369-72cjogxz 6312 7 . . . cord-015369-72cjogxz 6313 1 Therapeutisch Therapeutisch NNP cord-015369-72cjogxz 6313 2 wurde wurde VBD cord-015369-72cjogxz 6313 3 eine eine NNP cord-015369-72cjogxz 6313 4 Tumorexstirpation Tumorexstirpation NNP cord-015369-72cjogxz 6313 5 in in IN cord-015369-72cjogxz 6313 6 toto toto NNP cord-015369-72cjogxz 6313 7 mit mit NNP cord-015369-72cjogxz 6313 8 Resektion Resektion NNP cord-015369-72cjogxz 6313 9 des des NNP cord-015369-72cjogxz 6313 10 Omentum Omentum NNP cord-015369-72cjogxz 6313 11 majus majus NN cord-015369-72cjogxz 6314 1 und und NNP cord-015369-72cjogxz 6315 1 atypischer atypischer NNP cord-015369-72cjogxz 6315 2 Leberresektion Leberresektion NNP cord-015369-72cjogxz 6316 1 i -PRON- PRP cord-015369-72cjogxz 6316 2 m be VBP cord-015369-72cjogxz 6316 3 Segment segment NN cord-015369-72cjogxz 6316 4 3 3 CD cord-015369-72cjogxz 6316 5 ausgeführt ausgeführt NN cord-015369-72cjogxz 6316 6 . . . cord-015369-72cjogxz 6317 1 Nach Nach NNP cord-015369-72cjogxz 6317 2 histomorphologischem histomorphologischem NNP cord-015369-72cjogxz 6318 1 Aspekt Aspekt NNP cord-015369-72cjogxz 6318 2 von von NNP cord-015369-72cjogxz 6318 3 Leberkapsel Leberkapsel NNP cord-015369-72cjogxz 6318 4 ausgegangenes ausgegangenes NNP cord-015369-72cjogxz 6318 5 , , , cord-015369-72cjogxz 6318 6 niedrig niedrig NNP cord-015369-72cjogxz 6318 7 malignes malignes NNPS cord-015369-72cjogxz 6318 8 Sarkom Sarkom NNP cord-015369-72cjogxz 6318 9 ( ( -LRB- cord-015369-72cjogxz 6318 10 Durchmesser Durchmesser NNP cord-015369-72cjogxz 6318 11 : : : cord-015369-72cjogxz 6318 12 25 25 CD cord-015369-72cjogxz 6318 13 cm cm NNS cord-015369-72cjogxz 6318 14 ; ; : cord-015369-72cjogxz 6318 15 Gewicht gewicht NN cord-015369-72cjogxz 6318 16 : : : cord-015369-72cjogxz 6318 17 2,350 2,350 CD cord-015369-72cjogxz 6318 18 g g NN cord-015369-72cjogxz 6318 19 ) ) -RRB- cord-015369-72cjogxz 6318 20 . . . cord-015369-72cjogxz 6319 1 Keine Keine NNP cord-015369-72cjogxz 6319 2 Leberinfiltration Leberinfiltration NNP cord-015369-72cjogxz 6319 3 , , , cord-015369-72cjogxz 6319 4 ü ü NN cord-015369-72cjogxz 6320 1 berwiegend berwiegend NNP cord-015369-72cjogxz 6320 2 myxoider myxoider NNP cord-015369-72cjogxz 6320 3 Background Background NNP cord-015369-72cjogxz 6320 4 , , , cord-015369-72cjogxz 6320 5 spindelzellige spindelzellige NNP cord-015369-72cjogxz 6320 6 , , , cord-015369-72cjogxz 6320 7 teils teils NNP cord-015369-72cjogxz 6320 8 pleomorphe pleomorphe NNP cord-015369-72cjogxz 6320 9 Tumorzellen Tumorzellen NNP cord-015369-72cjogxz 6320 10 mit mit NNP cord-015369-72cjogxz 6320 11 Hyperchromasie Hyperchromasie NNP cord-015369-72cjogxz 6320 12 , , , cord-015369-72cjogxz 6320 13 faseriges faserige VBZ cord-015369-72cjogxz 6320 14 Stroma Stroma NNP cord-015369-72cjogxz 6320 15 ( ( -LRB- cord-015369-72cjogxz 6320 16 Immunhistochemisch Immunhistochemisch NNP cord-015369-72cjogxz 6320 17 : : : cord-015369-72cjogxz 6320 18 glattmuskuläres glattmuskuläres NNP cord-015369-72cjogxz 6320 19 Aktin Aktin NNP cord-015369-72cjogxz 6320 20 : : : cord-015369-72cjogxz 6321 1 þ þ LS cord-015369-72cjogxz 6321 2 ; ; . cord-015369-72cjogxz 6322 1 Desmin Desmin NNP cord-015369-72cjogxz 6322 2 / / SYM cord-015369-72cjogxz 6322 3 S100 S100 NNP cord-015369-72cjogxz 6322 4 / / SYM cord-015369-72cjogxz 6322 5 Ö Ö NNP cord-015369-72cjogxz 6322 6 strogen strogen NN cord-015369-72cjogxz 6322 7 - - HYPH cord-015369-72cjogxz 6322 8 und und NNP cord-015369-72cjogxz 6323 1 Progesteronrezeptor Progesteronrezeptor NNP cord-015369-72cjogxz 6323 2 / / SYM cord-015369-72cjogxz 6323 3 CD31 CD31 NNP cord-015369-72cjogxz 6323 4 / / SYM cord-015369-72cjogxz 6323 5 CD34 CD34 NNP cord-015369-72cjogxz 6323 6 / / SYM cord-015369-72cjogxz 6323 7 CD117 cd117 NN cord-015369-72cjogxz 6324 1 : : : cord-015369-72cjogxz 6324 2 Negativ Negativ NNP cord-015369-72cjogxz 6324 3 ) ) -RRB- cord-015369-72cjogxz 6324 4 . . . cord-015369-72cjogxz 6325 1 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 6325 2 tumorfrei tumorfrei NN cord-015369-72cjogxz 6325 3 . . . cord-015369-72cjogxz 6326 1 14 14 CD cord-015369-72cjogxz 6326 2 Monate Monate NNP cord-015369-72cjogxz 6326 3 nach nach NNP cord-015369-72cjogxz 6326 4 Tumorresektion Tumorresektion NNP cord-015369-72cjogxz 6326 5 war war NN cord-015369-72cjogxz 6326 6 kein kein NN cord-015369-72cjogxz 6326 7 Tumorrezidiv Tumorrezidiv NNP cord-015369-72cjogxz 6326 8 zu zu NNP cord-015369-72cjogxz 6326 9 verzeichnen verzeichnen NNP cord-015369-72cjogxz 6326 10 . . . cord-015369-72cjogxz 6327 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6327 2 . . . cord-015369-72cjogxz 6328 1 Der Der NNP cord-015369-72cjogxz 6328 2 bisher bisher NN cord-015369-72cjogxz 6328 3 älteste älteste NN cord-015369-72cjogxz 6328 4 berichtete berichtete NNP cord-015369-72cjogxz 6328 5 Patient Patient NNP cord-015369-72cjogxz 6328 6 ist ist NNP cord-015369-72cjogxz 6328 7 78 78 CD cord-015369-72cjogxz 6328 8 Jahre Jahre NNP cord-015369-72cjogxz 6328 9 alt alt NN cord-015369-72cjogxz 6328 10 . . . cord-015369-72cjogxz 6329 1 Der Der NNP cord-015369-72cjogxz 6329 2 vorliegende vorliegende NNP cord-015369-72cjogxz 6329 3 Fall Fall NNP cord-015369-72cjogxz 6329 4 steht steht NNP cord-015369-72cjogxz 6329 5 also also RB cord-015369-72cjogxz 6329 6 , , , cord-015369-72cjogxz 6329 7 insbesondere insbesondere NNP cord-015369-72cjogxz 6330 1 i -PRON- PRP cord-015369-72cjogxz 6330 2 m be VBP cord-015369-72cjogxz 6330 3 Hinblick Hinblick NNP cord-015369-72cjogxz 6330 4 auf auf NNP cord-015369-72cjogxz 6330 5 das das NNP cord-015369-72cjogxz 6330 6 fortgeschrittene fortgeschrittene NNP cord-015369-72cjogxz 6330 7 Alter Alter NNP cord-015369-72cjogxz 6330 8 der der NNP cord-015369-72cjogxz 6330 9 Patientin Patientin NNP cord-015369-72cjogxz 6330 10 und und TO cord-015369-72cjogxz 6330 11 die die VBP cord-015369-72cjogxz 6330 12 Lokalisation Lokalisation NNP cord-015369-72cjogxz 6330 13 eine eine NNP cord-015369-72cjogxz 6330 14 ausgesprochene ausgesprochene NN cord-015369-72cjogxz 6330 15 Rarität Rarität NNP cord-015369-72cjogxz 6330 16 dar dar NNP cord-015369-72cjogxz 6330 17 . . . cord-015369-72cjogxz 6331 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6331 2 . . . cord-015369-72cjogxz 6332 1 Die die VB cord-015369-72cjogxz 6332 2 elektrische elektrische NN cord-015369-72cjogxz 6333 1 Impedanz Impedanz NNP cord-015369-72cjogxz 6333 2 - - HYPH cord-015369-72cjogxz 6333 3 Tomographie Tomographie NNP cord-015369-72cjogxz 6333 4 ( ( -LRB- cord-015369-72cjogxz 6333 5 EIT EIT NNP cord-015369-72cjogxz 6333 6 ) ) -RRB- cord-015369-72cjogxz 6333 7 stellt stellt NNP cord-015369-72cjogxz 6333 8 eine eine NNP cord-015369-72cjogxz 6333 9 nicht nicht FW cord-015369-72cjogxz 6333 10 invasive invasive JJ cord-015369-72cjogxz 6333 11 Methode Methode NNP cord-015369-72cjogxz 6333 12 zur zur NNP cord-015369-72cjogxz 6333 13 Darstellung Darstellung NNP cord-015369-72cjogxz 6333 14 der der NN cord-015369-72cjogxz 6333 15 lokalen lokalen NNP cord-015369-72cjogxz 6333 16 Lungenventilation Lungenventilation NNP cord-015369-72cjogxz 6333 17 sowie sowie NNP cord-015369-72cjogxz 6333 18 der der NNP cord-015369-72cjogxz 6333 19 Lungenwasserverteilung Lungenwasserverteilung NNP cord-015369-72cjogxz 6333 20 dar dar NNP cord-015369-72cjogxz 6333 21 . . . cord-015369-72cjogxz 6334 1 Intrapulmonale Intrapulmonale NNP cord-015369-72cjogxz 6334 2 Flüssigkeitsverschiebungen Flüssigkeitsverschiebungen NNP cord-015369-72cjogxz 6334 3 können können NNP cord-015369-72cjogxz 6334 4 beobachtet beobachtet NNP cord-015369-72cjogxz 6334 5 werden werden NNP cord-015369-72cjogxz 6334 6 bei bei NNP cord-015369-72cjogxz 6334 7 Lageveränderungen Lageveränderungen NNP cord-015369-72cjogxz 6334 8 des des NNP cord-015369-72cjogxz 6334 9 Körpers Körpers NNP cord-015369-72cjogxz 6335 1 oder oder NNP cord-015369-72cjogxz 6335 2 als als NNP cord-015369-72cjogxz 6335 3 pathologische pathologische NN cord-015369-72cjogxz 6335 4 Veränderungen Veränderungen NNP cord-015369-72cjogxz 6336 1 wie wie NNP cord-015369-72cjogxz 6336 2 sie sie NNP cord-015369-72cjogxz 6336 3 zum zum NNP cord-015369-72cjogxz 6336 4 Beispiel Beispiel NNP cord-015369-72cjogxz 6336 5 i -PRON- PRP cord-015369-72cjogxz 6336 6 m be VBP cord-015369-72cjogxz 6336 7 Rahmen Rahmen NNP cord-015369-72cjogxz 6336 8 eines eines NNPS cord-015369-72cjogxz 6336 9 Lungenödems Lungenödems NNPS cord-015369-72cjogxz 6336 10 auftreten auftreten NN cord-015369-72cjogxz 6336 11 . . . cord-015369-72cjogxz 6337 1 Interessanterweise Interessanterweise NNP cord-015369-72cjogxz 6337 2 kann kann NNP cord-015369-72cjogxz 6337 3 auch auch NNP cord-015369-72cjogxz 6337 4 ein ein NNP cord-015369-72cjogxz 6337 5 direkter direkter NNP cord-015369-72cjogxz 6337 6 Einfuß Einfuß NNP cord-015369-72cjogxz 6337 7 der der NNP cord-015369-72cjogxz 6337 8 regionalen regionalen NNP cord-015369-72cjogxz 6338 1 Lungenventilation lungenventilation NN cord-015369-72cjogxz 6338 2 zur zur NNP cord-015369-72cjogxz 6338 3 Lage Lage NNP cord-015369-72cjogxz 6338 4 des des NNP cord-015369-72cjogxz 6338 5 Körpers Körpers NNP cord-015369-72cjogxz 6339 1 i -PRON- PRP cord-015369-72cjogxz 6339 2 m be VBP cord-015369-72cjogxz 6339 3 Raum Raum NNP cord-015369-72cjogxz 6339 4 dargestellt dargestellt NN cord-015369-72cjogxz 6339 5 werden werden NNP cord-015369-72cjogxz 6339 6 . . . cord-015369-72cjogxz 6340 1 Weiters Weiters NNP cord-015369-72cjogxz 6340 2 zeigten zeigten NNP cord-015369-72cjogxz 6341 1 mehrere mehrere NNP cord-015369-72cjogxz 6341 2 Studien Studien NNP cord-015369-72cjogxz 6341 3 das das NNP cord-015369-72cjogxz 6341 4 Lungenteile Lungenteile NNP cord-015369-72cjogxz 6341 5 die die VBP cord-015369-72cjogxz 6341 6 unter unter NNP cord-015369-72cjogxz 6341 7 einem einem NNP cord-015369-72cjogxz 6341 8 höheren höheren NNP cord-015369-72cjogxz 6342 1 mechanischen mechanischen NNP cord-015369-72cjogxz 6342 2 Stress Stress NNP cord-015369-72cjogxz 6342 3 stehen stehen NNP cord-015369-72cjogxz 6342 4 besser besser NNP cord-015369-72cjogxz 6342 5 ventiliert ventiliert NNP cord-015369-72cjogxz 6342 6 werden werden NNP cord-015369-72cjogxz 6342 7 als als NNP cord-015369-72cjogxz 6342 8 die die VBP cord-015369-72cjogxz 6343 1 restlichen restlichen NNP cord-015369-72cjogxz 6343 2 Lungenregionen Lungenregionen NNP cord-015369-72cjogxz 6343 3 . . . cord-015369-72cjogxz 6344 1 Methodik Methodik NNP cord-015369-72cjogxz 6344 2 . . . cord-015369-72cjogxz 6345 1 Die die VB cord-015369-72cjogxz 6345 2 Messungen Messungen NNP cord-015369-72cjogxz 6345 3 wurden wurden VBD cord-015369-72cjogxz 6345 4 an an DT cord-015369-72cjogxz 6345 5 6 6 CD cord-015369-72cjogxz 6345 6 gesunden gesunden JJ cord-015369-72cjogxz 6345 7 männlichen männlichen NNP cord-015369-72cjogxz 6345 8 Probanden Probanden NNP cord-015369-72cjogxz 6345 9 durchgeführt durchgeführt NN cord-015369-72cjogxz 6345 10 mithilfe mithilfe NNP cord-015369-72cjogxz 6345 11 des des NNP cord-015369-72cjogxz 6345 12 , , , cord-015369-72cjogxz 6345 13 , , , cord-015369-72cjogxz 6345 14 multichannel multichannel JJ cord-015369-72cjogxz 6345 15 impedance impedance NN cord-015369-72cjogxz 6345 16 spectroscope spectroscope NN cord-015369-72cjogxz 6345 17 MXS1 MXS1 NNP cord-015369-72cjogxz 6345 18 ( ( -LRB- cord-015369-72cjogxz 6345 19 Osypka Osypka NNP cord-015369-72cjogxz 6345 20 Medical Medical NNP cord-015369-72cjogxz 6345 21 Gmbh Gmbh NNP cord-015369-72cjogxz 6345 22 ) ) -RRB- cord-015369-72cjogxz 6345 23 . . . cord-015369-72cjogxz 6346 1 Für Für NNP cord-015369-72cjogxz 6346 2 die die VBP cord-015369-72cjogxz 6347 1 Dauer Dauer NNP cord-015369-72cjogxz 6347 2 der der NNP cord-015369-72cjogxz 6347 3 Messung Messung NNP cord-015369-72cjogxz 6347 4 wurden wurden NNS cord-015369-72cjogxz 6347 5 die die VBP cord-015369-72cjogxz 6347 6 Probanden Probanden NNP cord-015369-72cjogxz 6347 7 in in IN cord-015369-72cjogxz 6347 8 ein ein NNP cord-015369-72cjogxz 6347 9 rotierendes rotierende VBZ cord-015369-72cjogxz 6347 10 Bett Bett NNP cord-015369-72cjogxz 6347 11 ( ( -LRB- cord-015369-72cjogxz 6347 12 RotoRest RotoRest NNP cord-015369-72cjogxz 6347 13 -KCI -KCI NNP cord-015369-72cjogxz 6347 14 Austria Austria NNP cord-015369-72cjogxz 6347 15 Gmbh)platziert Gmbh)platziert NNP cord-015369-72cjogxz 6347 16 mit mit NNP cord-015369-72cjogxz 6347 17 einer einer NNP cord-015369-72cjogxz 6347 18 kontinuierlichen kontinuierlichen NNP cord-015369-72cjogxz 6347 19 Rotationsgeschwindigkeit Rotationsgeschwindigkeit NNP cord-015369-72cjogxz 6347 20 von von NNP cord-015369-72cjogxz 6347 21 annähernd annähernd NNP cord-015369-72cjogxz 6347 22 30 30 CD cord-015369-72cjogxz 6347 23 pro pro JJ cord-015369-72cjogxz 6347 24 Minute minute NN cord-015369-72cjogxz 6347 25 . . . cord-015369-72cjogxz 6348 1 Die die VB cord-015369-72cjogxz 6348 2 Messungen Messungen NNP cord-015369-72cjogxz 6348 3 beinhalteten beinhalteten NNP cord-015369-72cjogxz 6348 4 die die NN cord-015369-72cjogxz 6348 5 waagrechte waagrechte NNS cord-015369-72cjogxz 6349 1 Position Position NNP cord-015369-72cjogxz 6349 2 sowie sowie NNP cord-015369-72cjogxz 6349 3 einen einen NNP cord-015369-72cjogxz 6349 4 62 62 CD cord-015369-72cjogxz 6350 1 Schwenk Schwenk NNP cord-015369-72cjogxz 6350 2 jeweils jeweil NNS cord-015369-72cjogxz 6351 1 nach nach NNP cord-015369-72cjogxz 6351 2 links links NNP cord-015369-72cjogxz 6351 3 und und IN cord-015369-72cjogxz 6351 4 rechts rechts NNP cord-015369-72cjogxz 6351 5 und und NNP cord-015369-72cjogxz 6351 6 endeten endeten NNP cord-015369-72cjogxz 6351 7 wieder wieder NNP cord-015369-72cjogxz 6351 8 in in IN cord-015369-72cjogxz 6351 9 der der NNP cord-015369-72cjogxz 6351 10 Waagrechten Waagrechten NNP cord-015369-72cjogxz 6352 1 für für NNP cord-015369-72cjogxz 6352 2 5 5 CD cord-015369-72cjogxz 6352 3 Minuten Minuten NNP cord-015369-72cjogxz 6352 4 . . . cord-015369-72cjogxz 6353 1 Mittels Mittels NNP cord-015369-72cjogxz 6353 2 Image image NN cord-015369-72cjogxz 6353 3 -Rekonstruktion -rekonstruktion NN cord-015369-72cjogxz 6353 4 konnte konnte NNP cord-015369-72cjogxz 6353 5 der der NNP cord-015369-72cjogxz 6353 6 Zeitpunkt Zeitpunkt NNP cord-015369-72cjogxz 6353 7 der der NNP cord-015369-72cjogxz 6353 8 Ventilation Ventilation NNP cord-015369-72cjogxz 6353 9 verschiedener verschiedener NNP cord-015369-72cjogxz 6353 10 Areale Areale NNP cord-015369-72cjogxz 6353 11 dann dann NNP cord-015369-72cjogxz 6353 12 bildlich bildlich NNP cord-015369-72cjogxz 6353 13 dargestellt dargestellt NNP cord-015369-72cjogxz 6353 14 werden werden NNP cord-015369-72cjogxz 6353 15 . . . cord-015369-72cjogxz 6354 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6354 2 . . . cord-015369-72cjogxz 6355 1 Bei Bei NNP cord-015369-72cjogxz 6355 2 allen allen NNP cord-015369-72cjogxz 6355 3 6 6 CD cord-015369-72cjogxz 6355 4 Probanden Probanden NNP cord-015369-72cjogxz 6355 5 konnte konnte NNP cord-015369-72cjogxz 6355 6 bewiesen bewiesen NNP cord-015369-72cjogxz 6355 7 werden werden NNP cord-015369-72cjogxz 6355 8 das das NNP cord-015369-72cjogxz 6355 9 immer immer NNP cord-015369-72cjogxz 6355 10 der der NNP cord-015369-72cjogxz 6355 11 mechanisch mechanisch NNP cord-015369-72cjogxz 6355 12 am be VBP cord-015369-72cjogxz 6355 13 stärksten stärksten NNP cord-015369-72cjogxz 6355 14 belastete belastete NNP cord-015369-72cjogxz 6355 15 Lungenabschnitt Lungenabschnitt NNP cord-015369-72cjogxz 6356 1 ( ( -LRB- cord-015369-72cjogxz 6356 2 Linksrotation linksrotation NN cord-015369-72cjogxz 6356 3 -linke -linke HYPH cord-015369-72cjogxz 6356 4 Lunge lunge VB cord-015369-72cjogxz 6356 5 , , , cord-015369-72cjogxz 6356 6 Rechtsrotation Rechtsrotation NNP cord-015369-72cjogxz 6356 7 - - HYPH cord-015369-72cjogxz 6356 8 rechte rechte NNP cord-015369-72cjogxz 6356 9 Lunge Lunge NNP cord-015369-72cjogxz 6356 10 , , , cord-015369-72cjogxz 6356 11 Waagrechte Waagrechte NNP cord-015369-72cjogxz 6356 12 -posteriore -posteriore HYPH cord-015369-72cjogxz 6356 13 Lungenabschnitte Lungenabschnitte NNP cord-015369-72cjogxz 6356 14 ) ) -RRB- cord-015369-72cjogxz 6357 1 bevorzugt bevorzugt NNP cord-015369-72cjogxz 6357 2 ventiliert ventiliert NNP cord-015369-72cjogxz 6357 3 werden werden NNP cord-015369-72cjogxz 6357 4 . . . cord-015369-72cjogxz 6358 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6358 2 . . . cord-015369-72cjogxz 6359 1 Die die VB cord-015369-72cjogxz 6359 2 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6359 3 dieser dieser NNP cord-015369-72cjogxz 6359 4 Studie Studie NNP cord-015369-72cjogxz 6359 5 zeigen zeigen NNP cord-015369-72cjogxz 6359 6 das das NNP cord-015369-72cjogxz 6359 7 EIT EIT NNP cord-015369-72cjogxz 6359 8 zukünftig zukünftig NN cord-015369-72cjogxz 6359 9 als als NN cord-015369-72cjogxz 6359 10 ausgezeichnete ausgezeichnete NN cord-015369-72cjogxz 6359 11 nicht nicht NNP cord-015369-72cjogxz 6359 12 invasive invasive JJ cord-015369-72cjogxz 6359 13 Untersuchungsmethode Untersuchungsmethode NNP cord-015369-72cjogxz 6359 14 zur zur NNP cord-015369-72cjogxz 6359 15 Beurteilung Beurteilung NNP cord-015369-72cjogxz 6359 16 der der NNP cord-015369-72cjogxz 6359 17 Lungenventilation Lungenventilation NNP cord-015369-72cjogxz 6359 18 dient dient NNP cord-015369-72cjogxz 6359 19 . . . cord-015369-72cjogxz 6360 1 Mögliche Mögliche NNP cord-015369-72cjogxz 6360 2 Einsatzorte Einsatzorte NNP cord-015369-72cjogxz 6360 3 wären wären XX cord-015369-72cjogxz 6360 4 zum zum NNP cord-015369-72cjogxz 6360 5 Beispiel Beispiel NNP cord-015369-72cjogxz 6360 6 Intensivstationen Intensivstationen NNP cord-015369-72cjogxz 6360 7 , , , cord-015369-72cjogxz 6360 8 wo wo MD cord-015369-72cjogxz 6360 9 auf auf VB cord-015369-72cjogxz 6360 10 relativ relativ JJ cord-015369-72cjogxz 6360 11 einfache einfache JJ cord-015369-72cjogxz 6360 12 Weise Weise NNP cord-015369-72cjogxz 6360 13 der der NN cord-015369-72cjogxz 6360 14 Erfolg Erfolg NNP cord-015369-72cjogxz 6361 1 von von NNP cord-015369-72cjogxz 6361 2 kinetischen kinetischen NNP cord-015369-72cjogxz 6361 3 Therapien Therapien NNP cord-015369-72cjogxz 6361 4 verifiziert verifiziert NN cord-015369-72cjogxz 6361 5 werden werden NNP cord-015369-72cjogxz 6361 6 kann kann NNP cord-015369-72cjogxz 6361 7 . . . cord-015369-72cjogxz 6362 1 Background background NN cord-015369-72cjogxz 6362 2 . . . cord-015369-72cjogxz 6363 1 Lichtenstein Lichtenstein NNP cord-015369-72cjogxz 6363 2 hernioplasty hernioplasty NNP cord-015369-72cjogxz 6363 3 is be VBZ cord-015369-72cjogxz 6363 4 a a DT cord-015369-72cjogxz 6363 5 very very RB cord-015369-72cjogxz 6363 6 common common JJ cord-015369-72cjogxz 6363 7 technique technique NN cord-015369-72cjogxz 6363 8 for for IN cord-015369-72cjogxz 6363 9 repairing repair VBG cord-015369-72cjogxz 6363 10 an an DT cord-015369-72cjogxz 6363 11 inguinal inguinal JJ cord-015369-72cjogxz 6363 12 hernia hernia NN cord-015369-72cjogxz 6363 13 and and CC cord-015369-72cjogxz 6363 14 foreign foreign JJ cord-015369-72cjogxz 6363 15 body body NN cord-015369-72cjogxz 6363 16 reaction reaction NN cord-015369-72cjogxz 6363 17 after after IN cord-015369-72cjogxz 6363 18 mesh mesh NN cord-015369-72cjogxz 6363 19 implantation implantation NN cord-015369-72cjogxz 6363 20 is be VBZ cord-015369-72cjogxz 6363 21 a a DT cord-015369-72cjogxz 6363 22 very very RB cord-015369-72cjogxz 6363 23 rare rare JJ cord-015369-72cjogxz 6363 24 complication complication NN cord-015369-72cjogxz 6363 25 . . . cord-015369-72cjogxz 6364 1 Case case NN cord-015369-72cjogxz 6364 2 report report NN cord-015369-72cjogxz 6364 3 . . . cord-015369-72cjogxz 6365 1 A a DT cord-015369-72cjogxz 6365 2 68-year 68-year JJ cord-015369-72cjogxz 6365 3 - - HYPH cord-015369-72cjogxz 6365 4 old old JJ cord-015369-72cjogxz 6365 5 patient patient NN cord-015369-72cjogxz 6365 6 with with IN cord-015369-72cjogxz 6365 7 an an DT cord-015369-72cjogxz 6365 8 inguinal inguinal JJ cord-015369-72cjogxz 6365 9 hernia hernia NN cord-015369-72cjogxz 6365 10 came come VBD cord-015369-72cjogxz 6365 11 to to IN cord-015369-72cjogxz 6365 12 our -PRON- PRP$ cord-015369-72cjogxz 6365 13 department department NN cord-015369-72cjogxz 6365 14 . . . cord-015369-72cjogxz 6366 1 We -PRON- PRP cord-015369-72cjogxz 6366 2 did do VBD cord-015369-72cjogxz 6366 3 a a DT cord-015369-72cjogxz 6366 4 Lichtenstein Lichtenstein NNP cord-015369-72cjogxz 6366 5 hernia hernia NN cord-015369-72cjogxz 6366 6 repair repair NN cord-015369-72cjogxz 6366 7 with with IN cord-015369-72cjogxz 6366 8 a a DT cord-015369-72cjogxz 6366 9 Paritex Paritex NNP cord-015369-72cjogxz 6366 10 Polyester Polyester NNP cord-015369-72cjogxz 6366 11 Mesh Mesh NNP cord-015369-72cjogxz 6366 12 ( ( -LRB- cord-015369-72cjogxz 6366 13 14.9 14.9 CD cord-015369-72cjogxz 6366 14 cm cm NNS cord-015369-72cjogxz 6366 15 ) ) -RRB- cord-015369-72cjogxz 6366 16 . . . cord-015369-72cjogxz 6367 1 Five five CD cord-015369-72cjogxz 6367 2 months month NNS cord-015369-72cjogxz 6367 3 later later RB cord-015369-72cjogxz 6367 4 the the DT cord-015369-72cjogxz 6367 5 patient patient NN cord-015369-72cjogxz 6367 6 came come VBD cord-015369-72cjogxz 6367 7 again again RB cord-015369-72cjogxz 6367 8 because because IN cord-015369-72cjogxz 6367 9 of of IN cord-015369-72cjogxz 6367 10 right right JJ cord-015369-72cjogxz 6367 11 inguinal inguinal JJ cord-015369-72cjogxz 6367 12 pain pain NN cord-015369-72cjogxz 6367 13 and and CC cord-015369-72cjogxz 6367 14 swelling swelling NN cord-015369-72cjogxz 6367 15 . . . cord-015369-72cjogxz 6368 1 Ultrasonography Ultrasonography NNP cord-015369-72cjogxz 6368 2 and and CC cord-015369-72cjogxz 6368 3 a a DT cord-015369-72cjogxz 6368 4 CT CT NNP cord-015369-72cjogxz 6368 5 - - HYPH cord-015369-72cjogxz 6368 6 scan scan NN cord-015369-72cjogxz 6368 7 were be VBD cord-015369-72cjogxz 6368 8 done do VBN cord-015369-72cjogxz 6368 9 . . . cord-015369-72cjogxz 6369 1 It -PRON- PRP cord-015369-72cjogxz 6369 2 showed show VBD cord-015369-72cjogxz 6369 3 three three CD cord-015369-72cjogxz 6369 4 liquid liquid JJ cord-015369-72cjogxz 6369 5 formations formation NNS cord-015369-72cjogxz 6369 6 in in IN cord-015369-72cjogxz 6369 7 the the DT cord-015369-72cjogxz 6369 8 right right JJ cord-015369-72cjogxz 6369 9 inguinal inguinal JJ cord-015369-72cjogxz 6369 10 region region NN cord-015369-72cjogxz 6369 11 . . . cord-015369-72cjogxz 6370 1 Blood blood NN cord-015369-72cjogxz 6370 2 test test NN cord-015369-72cjogxz 6370 3 showed show VBD cord-015369-72cjogxz 6370 4 signs sign NNS cord-015369-72cjogxz 6370 5 of of IN cord-015369-72cjogxz 6370 6 a a DT cord-015369-72cjogxz 6370 7 moderate moderate JJ cord-015369-72cjogxz 6370 8 inflamation inflamation NN cord-015369-72cjogxz 6370 9 , , , cord-015369-72cjogxz 6370 10 no no DT cord-015369-72cjogxz 6370 11 feaver feaver NN cord-015369-72cjogxz 6370 12 . . . cord-015369-72cjogxz 6371 1 We -PRON- PRP cord-015369-72cjogxz 6371 2 described describe VBD cord-015369-72cjogxz 6371 3 Antibiotics Antibiotics NNP cord-015369-72cjogxz 6371 4 and and CC cord-015369-72cjogxz 6371 5 NSAR NSAR NNP cord-015369-72cjogxz 6371 6 . . . cord-015369-72cjogxz 6372 1 A a DT cord-015369-72cjogxz 6372 2 few few JJ cord-015369-72cjogxz 6372 3 days day NNS cord-015369-72cjogxz 6372 4 later later RB cord-015369-72cjogxz 6372 5 we -PRON- PRP cord-015369-72cjogxz 6372 6 did do VBD cord-015369-72cjogxz 6372 7 a a DT cord-015369-72cjogxz 6372 8 punction punction NN cord-015369-72cjogxz 6372 9 which which WDT cord-015369-72cjogxz 6372 10 showed show VBD cord-015369-72cjogxz 6372 11 pus pus NN cord-015369-72cjogxz 6372 12 . . . cord-015369-72cjogxz 6373 1 A a DT cord-015369-72cjogxz 6373 2 reoperation reoperation NN cord-015369-72cjogxz 6373 3 was be VBD cord-015369-72cjogxz 6373 4 performed perform VBN cord-015369-72cjogxz 6373 5 . . . cord-015369-72cjogxz 6374 1 An an DT cord-015369-72cjogxz 6374 2 abscess abscess NN cord-015369-72cjogxz 6374 3 formation formation NN cord-015369-72cjogxz 6374 4 subcutaneously subcutaneously RB cord-015369-72cjogxz 6374 5 was be VBD cord-015369-72cjogxz 6374 6 laid lay VBN cord-015369-72cjogxz 6374 7 open open JJ cord-015369-72cjogxz 6374 8 . . . cord-015369-72cjogxz 6375 1 The the DT cord-015369-72cjogxz 6375 2 smear smear NN cord-015369-72cjogxz 6375 3 culture culture NN cord-015369-72cjogxz 6375 4 was be VBD cord-015369-72cjogxz 6375 5 steril steril JJ cord-015369-72cjogxz 6375 6 . . . cord-015369-72cjogxz 6376 1 During during IN cord-015369-72cjogxz 6376 2 the the DT cord-015369-72cjogxz 6376 3 first first JJ cord-015369-72cjogxz 6376 4 month month NN cord-015369-72cjogxz 6376 5 post post NN cord-015369-72cjogxz 6376 6 operation operation NN cord-015369-72cjogxz 6376 7 the the DT cord-015369-72cjogxz 6376 8 patient patient NN cord-015369-72cjogxz 6376 9 felt feel VBD cord-015369-72cjogxz 6376 10 well well RB cord-015369-72cjogxz 6376 11 , , , cord-015369-72cjogxz 6376 12 but but CC cord-015369-72cjogxz 6376 13 there there EX cord-015369-72cjogxz 6376 14 was be VBD cord-015369-72cjogxz 6376 15 still still RB cord-015369-72cjogxz 6376 16 serous serous JJ cord-015369-72cjogxz 6376 17 secretion secretion NN cord-015369-72cjogxz 6376 18 from from IN cord-015369-72cjogxz 6376 19 a a DT cord-015369-72cjogxz 6376 20 fistulous fistulous JJ cord-015369-72cjogxz 6376 21 tract tract NN cord-015369-72cjogxz 6376 22 . . . cord-015369-72cjogxz 6377 1 Two two CD cord-015369-72cjogxz 6377 2 and and CC cord-015369-72cjogxz 6377 3 a a DT cord-015369-72cjogxz 6377 4 half half NN cord-015369-72cjogxz 6377 5 months month NNS cord-015369-72cjogxz 6377 6 post post NN cord-015369-72cjogxz 6377 7 operation operation NN cord-015369-72cjogxz 6378 1 an an DT cord-015369-72cjogxz 6378 2 MRI MRI NNP cord-015369-72cjogxz 6378 3 Scan Scan NNP cord-015369-72cjogxz 6378 4 was be VBD cord-015369-72cjogxz 6378 5 performed perform VBN cord-015369-72cjogxz 6378 6 which which WDT cord-015369-72cjogxz 6378 7 showed show VBD cord-015369-72cjogxz 6378 8 a a DT cord-015369-72cjogxz 6378 9 abscess abscess NN cord-015369-72cjogxz 6378 10 formation formation NN cord-015369-72cjogxz 6378 11 involving involve VBG cord-015369-72cjogxz 6378 12 the the DT cord-015369-72cjogxz 6378 13 inguinal inguinal JJ cord-015369-72cjogxz 6378 14 canal canal NN cord-015369-72cjogxz 6378 15 . . . cord-015369-72cjogxz 6379 1 At at IN cord-015369-72cjogxz 6379 2 re re NN cord-015369-72cjogxz 6379 3 - - NN cord-015369-72cjogxz 6379 4 operation operation NN cord-015369-72cjogxz 6379 5 we -PRON- PRP cord-015369-72cjogxz 6379 6 found find VBD cord-015369-72cjogxz 6379 7 serous serous JJ cord-015369-72cjogxz 6379 8 fluid fluid NN cord-015369-72cjogxz 6379 9 , , , cord-015369-72cjogxz 6379 10 an an DT cord-015369-72cjogxz 6379 11 intact intact JJ cord-015369-72cjogxz 6379 12 mesh mesh NN cord-015369-72cjogxz 6379 13 surrounded surround VBN cord-015369-72cjogxz 6379 14 by by IN cord-015369-72cjogxz 6379 15 inflamated inflamated JJ cord-015369-72cjogxz 6379 16 tissue tissue NN cord-015369-72cjogxz 6379 17 . . . cord-015369-72cjogxz 6380 1 We -PRON- PRP cord-015369-72cjogxz 6380 2 removed remove VBD cord-015369-72cjogxz 6380 3 the the DT cord-015369-72cjogxz 6380 4 mesh mesh NN cord-015369-72cjogxz 6380 5 , , , cord-015369-72cjogxz 6380 6 a a DT cord-015369-72cjogxz 6380 7 Bassini Bassini NNP cord-015369-72cjogxz 6380 8 's 's POS cord-015369-72cjogxz 6380 9 procedure procedure NN cord-015369-72cjogxz 6380 10 was be VBD cord-015369-72cjogxz 6380 11 performed perform VBN cord-015369-72cjogxz 6380 12 and and CC cord-015369-72cjogxz 6380 13 the the DT cord-015369-72cjogxz 6380 14 patient patient NN cord-015369-72cjogxz 6380 15 got get VBD cord-015369-72cjogxz 6380 16 antibiotics antibiotic NNS cord-015369-72cjogxz 6380 17 . . . cord-015369-72cjogxz 6381 1 In in IN cord-015369-72cjogxz 6381 2 the the DT cord-015369-72cjogxz 6381 3 smear smear NN cord-015369-72cjogxz 6381 4 culture culture NN cord-015369-72cjogxz 6381 5 we -PRON- PRP cord-015369-72cjogxz 6381 6 could could MD cord-015369-72cjogxz 6381 7 n't not RB cord-015369-72cjogxz 6381 8 find find VB cord-015369-72cjogxz 6381 9 any any DT cord-015369-72cjogxz 6381 10 microorganismus microorganismus NN cord-015369-72cjogxz 6381 11 . . . cord-015369-72cjogxz 6382 1 Histologically histologically RB cord-015369-72cjogxz 6382 2 a a DT cord-015369-72cjogxz 6382 3 chronic chronic JJ cord-015369-72cjogxz 6382 4 granulomatous granulomatous JJ cord-015369-72cjogxz 6382 5 foreign foreign JJ cord-015369-72cjogxz 6382 6 body body NN cord-015369-72cjogxz 6382 7 reaction reaction NN cord-015369-72cjogxz 6382 8 was be VBD cord-015369-72cjogxz 6382 9 found find VBN cord-015369-72cjogxz 6382 10 . . . cord-015369-72cjogxz 6383 1 The the DT cord-015369-72cjogxz 6383 2 finding finding NN cord-015369-72cjogxz 6383 3 was be VBD cord-015369-72cjogxz 6383 4 a a DT cord-015369-72cjogxz 6383 5 proof proof NN cord-015369-72cjogxz 6383 6 for for IN cord-015369-72cjogxz 6383 7 a a DT cord-015369-72cjogxz 6383 8 foreign foreign JJ cord-015369-72cjogxz 6383 9 body body NN cord-015369-72cjogxz 6383 10 reaction reaction NN cord-015369-72cjogxz 6383 11 . . . cord-015369-72cjogxz 6384 1 In in IN cord-015369-72cjogxz 6384 2 the the DT cord-015369-72cjogxz 6384 3 following follow VBG cord-015369-72cjogxz 6384 4 controlls controll NNS cord-015369-72cjogxz 6384 5 the the DT cord-015369-72cjogxz 6384 6 patient patient NN cord-015369-72cjogxz 6384 7 did do VBD cord-015369-72cjogxz 6384 8 n't not RB cord-015369-72cjogxz 6384 9 have have VB cord-015369-72cjogxz 6384 10 any any DT cord-015369-72cjogxz 6384 11 further further JJ cord-015369-72cjogxz 6384 12 problems problem NNS cord-015369-72cjogxz 6384 13 . . . cord-015369-72cjogxz 6385 1 Methods method NNS cord-015369-72cjogxz 6385 2 . . . cord-015369-72cjogxz 6386 1 We -PRON- PRP cord-015369-72cjogxz 6386 2 report report VBP cord-015369-72cjogxz 6386 3 on on IN cord-015369-72cjogxz 6386 4 two two CD cord-015369-72cjogxz 6386 5 patients patient NNS cord-015369-72cjogxz 6386 6 , , , cord-015369-72cjogxz 6386 7 who who WP cord-015369-72cjogxz 6386 8 developed develop VBD cord-015369-72cjogxz 6386 9 massive massive JJ cord-015369-72cjogxz 6386 10 postoperative postoperative JJ cord-015369-72cjogxz 6386 11 PE PE NNP cord-015369-72cjogxz 6386 12 and and CC cord-015369-72cjogxz 6386 13 received receive VBD cord-015369-72cjogxz 6386 14 sildenafil sildenafil NN cord-015369-72cjogxz 6386 15 as as IN cord-015369-72cjogxz 6386 16 an an DT cord-015369-72cjogxz 6386 17 adjuct adjuct NN cord-015369-72cjogxz 6386 18 to to IN cord-015369-72cjogxz 6386 19 thrombolytic thrombolytic NN cord-015369-72cjogxz 6386 20 therapy therapy NN cord-015369-72cjogxz 6386 21 . . . cord-015369-72cjogxz 6387 1 Results result NNS cord-015369-72cjogxz 6387 2 . . . cord-015369-72cjogxz 6388 1 The the DT cord-015369-72cjogxz 6388 2 first first JJ cord-015369-72cjogxz 6388 3 patient patient NN cord-015369-72cjogxz 6388 4 underwent undergo VBD cord-015369-72cjogxz 6388 5 gastric gastric JJ cord-015369-72cjogxz 6388 6 wedge wedge NN cord-015369-72cjogxz 6388 7 resection resection NN cord-015369-72cjogxz 6388 8 for for IN cord-015369-72cjogxz 6388 9 a a DT cord-015369-72cjogxz 6388 10 large large JJ cord-015369-72cjogxz 6388 11 perforated perforated JJ cord-015369-72cjogxz 6388 12 gastric gastric JJ cord-015369-72cjogxz 6388 13 ulcer ulcer NN cord-015369-72cjogxz 6388 14 after after IN cord-015369-72cjogxz 6388 15 initiation initiation NN cord-015369-72cjogxz 6388 16 of of IN cord-015369-72cjogxz 6388 17 interferon interferon NN cord-015369-72cjogxz 6388 18 / / SYM cord-015369-72cjogxz 6388 19 stroid stroid NNP cord-015369-72cjogxz 6388 20 therapy therapy NN cord-015369-72cjogxz 6388 21 for for IN cord-015369-72cjogxz 6388 22 multiple multiple JJ cord-015369-72cjogxz 6388 23 sclerosis sclerosis NN cord-015369-72cjogxz 6388 24 . . . cord-015369-72cjogxz 6389 1 On on IN cord-015369-72cjogxz 6389 2 the the DT cord-015369-72cjogxz 6389 3 evening evening NN cord-015369-72cjogxz 6389 4 after after IN cord-015369-72cjogxz 6389 5 discharge discharge NN cord-015369-72cjogxz 6389 6 , , , cord-015369-72cjogxz 6389 7 she -PRON- PRP cord-015369-72cjogxz 6389 8 was be VBD cord-015369-72cjogxz 6389 9 admitted admit VBN cord-015369-72cjogxz 6389 10 to to IN cord-015369-72cjogxz 6389 11 the the DT cord-015369-72cjogxz 6389 12 emergency emergency NN cord-015369-72cjogxz 6389 13 room room NN cord-015369-72cjogxz 6389 14 with with IN cord-015369-72cjogxz 6389 15 acute acute JJ cord-015369-72cjogxz 6389 16 dyspnea dyspnea NN cord-015369-72cjogxz 6389 17 and and CC cord-015369-72cjogxz 6389 18 cardiac cardiac JJ cord-015369-72cjogxz 6389 19 failure failure NN cord-015369-72cjogxz 6389 20 and and CC cord-015369-72cjogxz 6389 21 diagnosed diagnose VBN cord-015369-72cjogxz 6389 22 with with IN cord-015369-72cjogxz 6389 23 massive massive JJ cord-015369-72cjogxz 6389 24 PE pe NN cord-015369-72cjogxz 6389 25 . . . cord-015369-72cjogxz 6390 1 She -PRON- PRP cord-015369-72cjogxz 6390 2 underwent undergo VBD cord-015369-72cjogxz 6390 3 mechanic mechanic NN cord-015369-72cjogxz 6390 4 - - HYPH cord-015369-72cjogxz 6390 5 pharmacological pharmacological JJ cord-015369-72cjogxz 6390 6 clot clot NN cord-015369-72cjogxz 6390 7 fragmentation fragmentation NN cord-015369-72cjogxz 6390 8 ( ( -LRB- cord-015369-72cjogxz 6390 9 Angio angio NN cord-015369-72cjogxz 6390 10 - - HYPH cord-015369-72cjogxz 6390 11 jet jet NN cord-015369-72cjogxz 6390 12 device device NN cord-015369-72cjogxz 6390 13 in in IN cord-015369-72cjogxz 6390 14 conjunction conjunction NN cord-015369-72cjogxz 6390 15 with with IN cord-015369-72cjogxz 6390 16 TPA TPA NNP cord-015369-72cjogxz 6390 17 using use VBG cord-015369-72cjogxz 6390 18 the the DT cord-015369-72cjogxz 6390 19 power power NN cord-015369-72cjogxz 6390 20 pulse pulse NN cord-015369-72cjogxz 6390 21 technique technique NN cord-015369-72cjogxz 6390 22 ) ) -RRB- cord-015369-72cjogxz 6390 23 . . . cord-015369-72cjogxz 6391 1 On on IN cord-015369-72cjogxz 6391 2 the the DT cord-015369-72cjogxz 6391 3 intensive intensive JJ cord-015369-72cjogxz 6391 4 care care NN cord-015369-72cjogxz 6391 5 unit unit NN cord-015369-72cjogxz 6391 6 , , , cord-015369-72cjogxz 6391 7 oral oral JJ cord-015369-72cjogxz 6391 8 sildenafil sildenafil NNP cord-015369-72cjogxz 6391 9 was be VBD cord-015369-72cjogxz 6391 10 started start VBN cord-015369-72cjogxz 6391 11 ( ( -LRB- cord-015369-72cjogxz 6391 12 50 50 CD cord-015369-72cjogxz 6391 13 mg mg NNS cord-015369-72cjogxz 6391 14 twice twice RB cord-015369-72cjogxz 6391 15 daily daily JJ cord-015369-72cjogxz 6391 16 ) ) -RRB- cord-015369-72cjogxz 6391 17 , , , cord-015369-72cjogxz 6391 18 which which WDT cord-015369-72cjogxz 6391 19 resulted result VBD cord-015369-72cjogxz 6391 20 in in IN cord-015369-72cjogxz 6391 21 significant significant JJ cord-015369-72cjogxz 6391 22 improvement improvement NN cord-015369-72cjogxz 6391 23 of of IN cord-015369-72cjogxz 6391 24 right right JJ cord-015369-72cjogxz 6391 25 heart heart NN cord-015369-72cjogxz 6391 26 failure failure NN cord-015369-72cjogxz 6391 27 . . . cord-015369-72cjogxz 6392 1 The the DT cord-015369-72cjogxz 6392 2 patient patient NN cord-015369-72cjogxz 6392 3 suffered suffer VBD cord-015369-72cjogxz 6392 4 renal renal JJ cord-015369-72cjogxz 6392 5 and and CC cord-015369-72cjogxz 6392 6 hepatic hepatic JJ cord-015369-72cjogxz 6392 7 failure failure NN cord-015369-72cjogxz 6392 8 , , , cord-015369-72cjogxz 6392 9 however however RB cord-015369-72cjogxz 6392 10 , , , cord-015369-72cjogxz 6392 11 ultimately ultimately RB cord-015369-72cjogxz 6392 12 recovered recover VBD cord-015369-72cjogxz 6392 13 with with IN cord-015369-72cjogxz 6392 14 restored restore VBN cord-015369-72cjogxz 6392 15 organ organ NN cord-015369-72cjogxz 6392 16 function function NN cord-015369-72cjogxz 6392 17 . . . cord-015369-72cjogxz 6393 1 She -PRON- PRP cord-015369-72cjogxz 6393 2 is be VBZ cord-015369-72cjogxz 6393 3 well well JJ cord-015369-72cjogxz 6393 4 and and CC cord-015369-72cjogxz 6393 5 alive alive JJ cord-015369-72cjogxz 6393 6 after after IN cord-015369-72cjogxz 6393 7 more more JJR cord-015369-72cjogxz 6393 8 than than IN cord-015369-72cjogxz 6393 9 one one CD cord-015369-72cjogxz 6393 10 year year NN cord-015369-72cjogxz 6393 11 . . . cord-015369-72cjogxz 6394 1 The the DT cord-015369-72cjogxz 6394 2 second second JJ cord-015369-72cjogxz 6394 3 patient patient NN cord-015369-72cjogxz 6394 4 developed develop VBD cord-015369-72cjogxz 6394 5 acute acute JJ cord-015369-72cjogxz 6394 6 PE PE NNP cord-015369-72cjogxz 6394 7 four four CD cord-015369-72cjogxz 6394 8 days day NNS cord-015369-72cjogxz 6394 9 after after IN cord-015369-72cjogxz 6394 10 liver liver NN cord-015369-72cjogxz 6394 11 transplantation transplantation NN cord-015369-72cjogxz 6394 12 for for IN cord-015369-72cjogxz 6394 13 primary primary JJ cord-015369-72cjogxz 6394 14 biliary biliary JJ cord-015369-72cjogxz 6394 15 cirrhosis cirrhosis NN cord-015369-72cjogxz 6394 16 . . . cord-015369-72cjogxz 6395 1 She -PRON- PRP cord-015369-72cjogxz 6395 2 was be VBD cord-015369-72cjogxz 6395 3 treated treat VBN cord-015369-72cjogxz 6395 4 with with IN cord-015369-72cjogxz 6395 5 systemic systemic JJ cord-015369-72cjogxz 6395 6 thrombolysis thrombolysis NN cord-015369-72cjogxz 6395 7 . . . cord-015369-72cjogxz 6396 1 Application Application NNP cord-015369-72cjogxz 6396 2 of of IN cord-015369-72cjogxz 6396 3 sildenafil sildenafil NN cord-015369-72cjogxz 6396 4 resulted result VBD cord-015369-72cjogxz 6396 5 in in IN cord-015369-72cjogxz 6396 6 significant significant JJ cord-015369-72cjogxz 6396 7 improvement improvement NN cord-015369-72cjogxz 6396 8 in in IN cord-015369-72cjogxz 6396 9 cardiac cardiac JJ cord-015369-72cjogxz 6396 10 output output NN cord-015369-72cjogxz 6396 11 and and CC cord-015369-72cjogxz 6396 12 right right JJ cord-015369-72cjogxz 6396 13 heart heart NN cord-015369-72cjogxz 6396 14 failure failure NN cord-015369-72cjogxz 6396 15 which which WDT cord-015369-72cjogxz 6396 16 caused cause VBD cord-015369-72cjogxz 6396 17 congestion congestion NN cord-015369-72cjogxz 6396 18 of of IN cord-015369-72cjogxz 6396 19 the the DT cord-015369-72cjogxz 6396 20 liver liver NN cord-015369-72cjogxz 6396 21 allograft allograft NN cord-015369-72cjogxz 6396 22 . . . cord-015369-72cjogxz 6397 1 She -PRON- PRP cord-015369-72cjogxz 6397 2 later later RB cord-015369-72cjogxz 6397 3 developed develop VBD cord-015369-72cjogxz 6397 4 Takotsubo Takotsubo NNP cord-015369-72cjogxz 6397 5 cardiomyopathy cardiomyopathy NN cord-015369-72cjogxz 6397 6 and and CC cord-015369-72cjogxz 6397 7 renal renal JJ cord-015369-72cjogxz 6397 8 failure failure NN cord-015369-72cjogxz 6397 9 , , , cord-015369-72cjogxz 6397 10 however however RB cord-015369-72cjogxz 6397 11 , , , cord-015369-72cjogxz 6397 12 recovered recover VBD cord-015369-72cjogxz 6397 13 from from IN cord-015369-72cjogxz 6397 14 these these DT cord-015369-72cjogxz 6397 15 complications complication NNS cord-015369-72cjogxz 6397 16 and and CC cord-015369-72cjogxz 6397 17 is be VBZ cord-015369-72cjogxz 6397 18 alive alive JJ cord-015369-72cjogxz 6397 19 with with IN cord-015369-72cjogxz 6397 20 good good JJ cord-015369-72cjogxz 6397 21 graft graft NN cord-015369-72cjogxz 6397 22 function function NN cord-015369-72cjogxz 6397 23 after after IN cord-015369-72cjogxz 6397 24 10 10 CD cord-015369-72cjogxz 6397 25 months month NNS cord-015369-72cjogxz 6397 26 . . . cord-015369-72cjogxz 6398 1 Conclusions conclusion NNS cord-015369-72cjogxz 6398 2 . . . cord-015369-72cjogxz 6399 1 Although although IN cord-015369-72cjogxz 6399 2 the the DT cord-015369-72cjogxz 6399 3 two two CD cord-015369-72cjogxz 6399 4 cases case NNS cord-015369-72cjogxz 6399 5 suggest suggest VBP cord-015369-72cjogxz 6399 6 that that IN cord-015369-72cjogxz 6399 7 sildenafil sildenafil NN cord-015369-72cjogxz 6399 8 may may MD cord-015369-72cjogxz 6399 9 be be VB cord-015369-72cjogxz 6399 10 a a DT cord-015369-72cjogxz 6399 11 useful useful JJ cord-015369-72cjogxz 6399 12 pharmacologic pharmacologic JJ cord-015369-72cjogxz 6399 13 intervention intervention NN cord-015369-72cjogxz 6399 14 in in IN cord-015369-72cjogxz 6399 15 acute acute JJ cord-015369-72cjogxz 6399 16 massive massive JJ cord-015369-72cjogxz 6399 17 postoperative postoperative JJ cord-015369-72cjogxz 6399 18 PE PE NNP cord-015369-72cjogxz 6399 19 , , , cord-015369-72cjogxz 6399 20 a a DT cord-015369-72cjogxz 6399 21 controlled control VBN cord-015369-72cjogxz 6399 22 trial trial NN cord-015369-72cjogxz 6399 23 is be VBZ cord-015369-72cjogxz 6399 24 necssary necssary JJ cord-015369-72cjogxz 6399 25 to to TO cord-015369-72cjogxz 6399 26 confirm confirm VB cord-015369-72cjogxz 6399 27 our -PRON- PRP$ cord-015369-72cjogxz 6399 28 findings finding NNS cord-015369-72cjogxz 6399 29 . . . cord-015369-72cjogxz 6400 1 Chirurgische Chirurgische NNP cord-015369-72cjogxz 6400 2 Therapie Therapie NNP cord-015369-72cjogxz 6400 3 des des FW cord-015369-72cjogxz 6400 4 katamenialen katamenialen NNP cord-015369-72cjogxz 6400 5 Pneumothorax Pneumothorax NNP cord-015369-72cjogxz 6400 6 W. W. NNP cord-015369-72cjogxz 6400 7 Kolb Kolb NNP cord-015369-72cjogxz 6400 8 , , , cord-015369-72cjogxz 6400 9 R. R. NNP cord-015369-72cjogxz 6400 10 Kuster Kuster NNP cord-015369-72cjogxz 6400 11 , , , cord-015369-72cjogxz 6400 12 W. W. NNP cord-015369-72cjogxz 6400 13 Nagel Nagel NNP cord-015369-72cjogxz 6400 14 Klinik Klinik NNP cord-015369-72cjogxz 6400 15 für für IN cord-015369-72cjogxz 6400 16 Chirurgie Chirurgie NNP cord-015369-72cjogxz 6400 17 , , , cord-015369-72cjogxz 6400 18 St. St. NNP cord-015369-72cjogxz 6400 19 Gallen Gallen NNP cord-015369-72cjogxz 6400 20 , , , cord-015369-72cjogxz 6400 21 Switzerland Switzerland NNP cord-015369-72cjogxz 6400 22 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6400 23 . . . cord-015369-72cjogxz 6401 1 Der Der NNP cord-015369-72cjogxz 6401 2 katameniale katameniale NNP cord-015369-72cjogxz 6402 1 Pneumothorax pneumothorax NN cord-015369-72cjogxz 6402 2 ist ist NNP cord-015369-72cjogxz 6402 3 eine eine NNP cord-015369-72cjogxz 6402 4 seltene seltene JJ cord-015369-72cjogxz 6402 5 Ursache Ursache NNP cord-015369-72cjogxz 6402 6 eines eines NNP cord-015369-72cjogxz 6402 7 Spontanpneumothorax Spontanpneumothorax NNP cord-015369-72cjogxz 6402 8 , , , cord-015369-72cjogxz 6402 9 der der NNP cord-015369-72cjogxz 6402 10 durch durch NNP cord-015369-72cjogxz 6402 11 eine eine NNP cord-015369-72cjogxz 6402 12 abdominale abdominale NNP cord-015369-72cjogxz 6402 13 bzw bzw NNP cord-015369-72cjogxz 6402 14 . . . cord-015369-72cjogxz 6403 1 thorakale thorakale NNP cord-015369-72cjogxz 6403 2 Endometriose Endometriose NNP cord-015369-72cjogxz 6403 3 verursacht verursacht NN cord-015369-72cjogxz 6403 4 wird wird NNP cord-015369-72cjogxz 6403 5 . . . cord-015369-72cjogxz 6404 1 Methodik Methodik NNP cord-015369-72cjogxz 6404 2 . . . cord-015369-72cjogxz 6405 1 Wir Wir NNP cord-015369-72cjogxz 6405 2 berichten berichten NNP cord-015369-72cjogxz 6405 3 ü ü NNP cord-015369-72cjogxz 6406 1 ber ber NNP cord-015369-72cjogxz 6406 2 drei drei NNP cord-015369-72cjogxz 6406 3 Patientinnen Patientinnen NNP cord-015369-72cjogxz 6406 4 , , , cord-015369-72cjogxz 6406 5 die die VBP cord-015369-72cjogxz 6406 6 aufgrund aufgrund NNP cord-015369-72cjogxz 6406 7 eines eine NNS cord-015369-72cjogxz 6407 1 rezidivierenden rezidivierenden NNP cord-015369-72cjogxz 6407 2 mensassoziierten mensassoziierten NNP cord-015369-72cjogxz 6407 3 rechtsseitigen rechtsseitigen NNP cord-015369-72cjogxz 6407 4 Spontanpneumothorax Spontanpneumothorax NNP cord-015369-72cjogxz 6408 1 an an DT cord-015369-72cjogxz 6408 2 unserer unserer JJ cord-015369-72cjogxz 6408 3 Klinik Klinik NNP cord-015369-72cjogxz 6408 4 behandelt behandelt NNP cord-015369-72cjogxz 6408 5 wurden wurden VBD cord-015369-72cjogxz 6408 6 . . . cord-015369-72cjogxz 6409 1 In in IN cord-015369-72cjogxz 6409 2 der der NNP cord-015369-72cjogxz 6409 3 Vergangenheit Vergangenheit NNP cord-015369-72cjogxz 6409 4 waren waren VBD cord-015369-72cjogxz 6409 5 zwei zwei NNP cord-015369-72cjogxz 6409 6 Patientinnen Patientinnen NNP cord-015369-72cjogxz 6409 7 bereits bereits NNP cord-015369-72cjogxz 6409 8 thorakoskopisch thorakoskopisch NNP cord-015369-72cjogxz 6409 9 mittels mittels NNP cord-015369-72cjogxz 6409 10 einer einer NNP cord-015369-72cjogxz 6409 11 Lungenspitzenwedgeresektion Lungenspitzenwedgeresektion NNP cord-015369-72cjogxz 6409 12 behandelt behandelt NNP cord-015369-72cjogxz 6409 13 worden worden NNP cord-015369-72cjogxz 6409 14 . . . cord-015369-72cjogxz 6410 1 Aktuell Aktuell NNP cord-015369-72cjogxz 6410 2 erfolgte erfolgte NN cord-015369-72cjogxz 6410 3 bei bei NNP cord-015369-72cjogxz 6410 4 allen allen NNP cord-015369-72cjogxz 6410 5 drei drei NNP cord-015369-72cjogxz 6410 6 Patientinnen Patientinnen NNP cord-015369-72cjogxz 6410 7 zunächst zunächst NNP cord-015369-72cjogxz 6411 1 eine eine NNP cord-015369-72cjogxz 6411 2 diagnostische diagnostische IN cord-015369-72cjogxz 6411 3 Thorakoskopie Thorakoskopie NNP cord-015369-72cjogxz 6411 4 zur zur NNP cord-015369-72cjogxz 6411 5 Diagnosesicherung Diagnosesicherung NNP cord-015369-72cjogxz 6411 6 . . . cord-015369-72cjogxz 6412 1 In in IN cord-015369-72cjogxz 6412 2 allen allen NNP cord-015369-72cjogxz 6412 3 Fällen Fällen NNP cord-015369-72cjogxz 6412 4 erfolgte erfolgte NN cord-015369-72cjogxz 6412 5 bei bei NNP cord-015369-72cjogxz 6412 6 ausgedehntem ausgedehntem NNP cord-015369-72cjogxz 6413 1 Befall befall VB cord-015369-72cjogxz 6413 2 des des FW cord-015369-72cjogxz 6413 3 Zwerchfelles Zwerchfelles NNP cord-015369-72cjogxz 6414 1 eine eine NNP cord-015369-72cjogxz 6414 2 Zwerchfellteilresektion Zwerchfellteilresektion NNP cord-015369-72cjogxz 6414 3 ü ü NN cord-015369-72cjogxz 6414 4 ber ber NNP cord-015369-72cjogxz 6414 5 eine eine NNP cord-015369-72cjogxz 6415 1 rechtsseitige rechtsseitige NNP cord-015369-72cjogxz 6415 2 Thorakotomie Thorakotomie NNP cord-015369-72cjogxz 6415 3 , , , cord-015369-72cjogxz 6415 4 in in IN cord-015369-72cjogxz 6415 5 einem einem NNP cord-015369-72cjogxz 6415 6 Fall Fall NNP cord-015369-72cjogxz 6415 7 erfolgte erfolgte NN cord-015369-72cjogxz 6415 8 die die VBP cord-015369-72cjogxz 6415 9 Implantation implantation NN cord-015369-72cjogxz 6415 10 eines eine NNS cord-015369-72cjogxz 6416 1 Kunststoffnetzes Kunststoffnetzes NNP cord-015369-72cjogxz 6416 2 zur zur NNP cord-015369-72cjogxz 6416 3 Defektdeckung Defektdeckung NNP cord-015369-72cjogxz 6416 4 . . . cord-015369-72cjogxz 6417 1 Die die VB cord-015369-72cjogxz 6417 2 Operationen Operationen NNP cord-015369-72cjogxz 6417 3 verliefen verliefen NNP cord-015369-72cjogxz 6417 4 durchwegs durchwegs NNP cord-015369-72cjogxz 6417 5 komplikationslos komplikationslos NNP cord-015369-72cjogxz 6417 6 . . . cord-015369-72cjogxz 6418 1 Histologisch Histologisch NNP cord-015369-72cjogxz 6418 2 konnte konnte NNP cord-015369-72cjogxz 6418 3 bei bei NNP cord-015369-72cjogxz 6418 4 allen allen NNP cord-015369-72cjogxz 6418 5 Patientinnen Patientinnen NNP cord-015369-72cjogxz 6418 6 anhand anhand NNP cord-015369-72cjogxz 6418 7 des des NNP cord-015369-72cjogxz 6418 8 Operationspräparates Operationspräparates NNP cord-015369-72cjogxz 6418 9 die die VBP cord-015369-72cjogxz 6418 10 präoperativ präoperativ JJ cord-015369-72cjogxz 6418 11 gestellte gestellte NNP cord-015369-72cjogxz 6419 1 Diagnose diagnose VB cord-015369-72cjogxz 6419 2 eines eine NNS cord-015369-72cjogxz 6419 3 katamenialen katamenialen NNP cord-015369-72cjogxz 6419 4 Pneumothorax Pneumothorax NNP cord-015369-72cjogxz 6419 5 bestätigt bestätigt NNP cord-015369-72cjogxz 6419 6 werden werden NNP cord-015369-72cjogxz 6419 7 . . . cord-015369-72cjogxz 6420 1 Postoperativ Postoperativ NNP cord-015369-72cjogxz 6420 2 wurde wurde VBD cord-015369-72cjogxz 6420 3 eine eine NNP cord-015369-72cjogxz 6420 4 konservative konservative FW cord-015369-72cjogxz 6420 5 Therapie Therapie NNP cord-015369-72cjogxz 6420 6 mit mit NNP cord-015369-72cjogxz 6420 7 Ovulationshemmern Ovulationshemmern NNP cord-015369-72cjogxz 6420 8 begonnen begonnen VBD cord-015369-72cjogxz 6420 9 bzw bzw NNP cord-015369-72cjogxz 6420 10 . . . cord-015369-72cjogxz 6421 1 fortgesetzt fortgesetzt NNP cord-015369-72cjogxz 6421 2 . . . cord-015369-72cjogxz 6422 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6422 2 . . . cord-015369-72cjogxz 6423 1 I -PRON- PRP cord-015369-72cjogxz 6423 2 m be VBP cord-015369-72cjogxz 6423 3 Rahmen Rahmen NNP cord-015369-72cjogxz 6423 4 der der NN cord-015369-72cjogxz 6423 5 Nachbeobachtungszeit Nachbeobachtungszeit NNP cord-015369-72cjogxz 6423 6 von von NNP cord-015369-72cjogxz 6423 7 nunmehr nunmehr NNP cord-015369-72cjogxz 6423 8 24 24 CD cord-015369-72cjogxz 6423 9 Monaten Monaten NNP cord-015369-72cjogxz 6423 10 ist ist NN cord-015369-72cjogxz 6423 11 bei bei NNP cord-015369-72cjogxz 6423 12 einer einer NNP cord-015369-72cjogxz 6423 13 Patientin Patientin NNP cord-015369-72cjogxz 6423 14 nach nach NNP cord-015369-72cjogxz 6423 15 Pausieren Pausieren NNP cord-015369-72cjogxz 6423 16 des des NNP cord-015369-72cjogxz 6424 1 Ovulationshemmers Ovulationshemmers NNP cord-015369-72cjogxz 6424 2 ein ein VBP cord-015369-72cjogxz 6425 1 neuerliches neuerliches NNP cord-015369-72cjogxz 6425 2 Rezidiv Rezidiv NNP cord-015369-72cjogxz 6425 3 eines eines NNP cord-015369-72cjogxz 6426 1 Spontanpneumothorax Spontanpneumothorax NNP cord-015369-72cjogxz 6426 2 aufgetreten aufgetreten VBD cord-015369-72cjogxz 6426 3 , , , cord-015369-72cjogxz 6426 4 welches welches NNP cord-015369-72cjogxz 6426 5 durch durch NNP cord-015369-72cjogxz 6426 6 Einlage Einlage NNP cord-015369-72cjogxz 6426 7 einer einer NNP cord-015369-72cjogxz 6426 8 Thoraxdrainage Thoraxdrainage NNP cord-015369-72cjogxz 6426 9 behandelt behandelt NNP cord-015369-72cjogxz 6426 10 werden werden NNP cord-015369-72cjogxz 6426 11 musste musste NNP cord-015369-72cjogxz 6426 12 . . . cord-015369-72cjogxz 6427 1 Die die VB cord-015369-72cjogxz 6427 2 beiden beiden NNP cord-015369-72cjogxz 6428 1 anderen anderen NNP cord-015369-72cjogxz 6428 2 Patientinnen Patientinnen NNP cord-015369-72cjogxz 6428 3 sind sind NNP cord-015369-72cjogxz 6428 4 beschwerde beschwerde NNP cord-015369-72cjogxz 6428 5 - - HYPH cord-015369-72cjogxz 6428 6 und und RB cord-015369-72cjogxz 6428 7 rezidivfrei rezidivfrei NN cord-015369-72cjogxz 6428 8 . . . cord-015369-72cjogxz 6429 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6429 2 . . . cord-015369-72cjogxz 6430 1 Benigne Benigne NNP cord-015369-72cjogxz 6430 2 fibröse fibröse NNP cord-015369-72cjogxz 6431 1 Tumore Tumore NNP cord-015369-72cjogxz 6431 2 der der NNP cord-015369-72cjogxz 6431 3 Pleura Pleura NNP cord-015369-72cjogxz 6431 4 sind sind NNP cord-015369-72cjogxz 6431 5 in in IN cord-015369-72cjogxz 6431 6 der der NNP cord-015369-72cjogxz 6431 7 Literatur Literatur NNP cord-015369-72cjogxz 6431 8 kaum kaum NNP cord-015369-72cjogxz 6431 9 beschrieben beschrieben NNP cord-015369-72cjogxz 6431 10 . . . cord-015369-72cjogxz 6432 1 Zu Zu NNP cord-015369-72cjogxz 6432 2 70 70 CD cord-015369-72cjogxz 6432 3 % % NN cord-015369-72cjogxz 6432 4 gehen gehen NNP cord-015369-72cjogxz 6432 5 diese diese NNP cord-015369-72cjogxz 6432 6 von von NNP cord-015369-72cjogxz 6432 7 der der NNP cord-015369-72cjogxz 6432 8 viszeralen viszeralen NNP cord-015369-72cjogxz 6432 9 Pleura Pleura NNP cord-015369-72cjogxz 6432 10 aus aus NNP cord-015369-72cjogxz 6432 11 . . . cord-015369-72cjogxz 6433 1 Methodik Methodik NNP cord-015369-72cjogxz 6433 2 . . . cord-015369-72cjogxz 6434 1 An an DT cord-015369-72cjogxz 6434 2 der der NNP cord-015369-72cjogxz 6434 3 Abteilung Abteilung NNP cord-015369-72cjogxz 6434 4 für für IN cord-015369-72cjogxz 6434 5 Herz Herz NNP cord-015369-72cjogxz 6434 6 - - HYPH cord-015369-72cjogxz 6434 7 Thorax Thorax NNP cord-015369-72cjogxz 6434 8 - - HYPH cord-015369-72cjogxz 6434 9 und und NNP cord-015369-72cjogxz 6434 10 Gefäßchirugie Gefäßchirugie NNP cord-015369-72cjogxz 6435 1 i i PRP cord-015369-72cjogxz 6436 1 m m LS cord-015369-72cjogxz 6436 2 LKH LKH NNP cord-015369-72cjogxz 6436 3 Klagenfurt Klagenfurt NNP cord-015369-72cjogxz 6437 1 wurde wurde NNP cord-015369-72cjogxz 6437 2 2008 2008 CD cord-015369-72cjogxz 6438 1 ein ein NNP cord-015369-72cjogxz 6439 1 64 64 CD cord-015369-72cjogxz 6439 2 jähriger jähriger NN cord-015369-72cjogxz 6439 3 männlicher männlicher NNP cord-015369-72cjogxz 6439 4 Patient Patient NNP cord-015369-72cjogxz 6439 5 aufgrund aufgrund NNP cord-015369-72cjogxz 6439 6 rezidivierender rezidivierender VBP cord-015369-72cjogxz 6439 7 Pleuraergüsse Pleuraergüsse NNP cord-015369-72cjogxz 6439 8 rechts rechts NN cord-015369-72cjogxz 6439 9 bei bei NNP cord-015369-72cjogxz 6439 10 bekanntem bekanntem NNP cord-015369-72cjogxz 6439 11 Zwerchfellhochstand Zwerchfellhochstand NNP cord-015369-72cjogxz 6439 12 rechts rechts NNP cord-015369-72cjogxz 6439 13 vorgestellt vorgestellt NNP cord-015369-72cjogxz 6439 14 . . . cord-015369-72cjogxz 6440 1 Klinisch Klinisch NNP cord-015369-72cjogxz 6440 2 präsentierte präsentierte NNP cord-015369-72cjogxz 6440 3 sich sich NNP cord-015369-72cjogxz 6440 4 der der NNP cord-015369-72cjogxz 6440 5 Patient Patient NNP cord-015369-72cjogxz 6440 6 mit mit NNP cord-015369-72cjogxz 6440 7 geringer geringer NN cord-015369-72cjogxz 6440 8 Dyspnoe Dyspnoe NNP cord-015369-72cjogxz 6440 9 ( ( -LRB- cord-015369-72cjogxz 6440 10 NYHA NYHA NNP cord-015369-72cjogxz 6440 11 II II NNP cord-015369-72cjogxz 6440 12 ) ) -RRB- cord-015369-72cjogxz 6441 1 nach nach NNP cord-015369-72cjogxz 6441 2 bereits bereits NNP cord-015369-72cjogxz 6442 1 erfolgten erfolgten NNP cord-015369-72cjogxz 6442 2 mehrmaligen mehrmaligen NNP cord-015369-72cjogxz 6442 3 Pleurapunktionen Pleurapunktionen NNP cord-015369-72cjogxz 6442 4 , , , cord-015369-72cjogxz 6442 5 welche welche NNP cord-015369-72cjogxz 6442 6 in in IN cord-015369-72cjogxz 6442 7 der der NNP cord-015369-72cjogxz 6442 8 zytolgischen zytolgischen NNP cord-015369-72cjogxz 6442 9 Diagnostik Diagnostik NNP cord-015369-72cjogxz 6442 10 keine keine NNP cord-015369-72cjogxz 6442 11 Besonderheiten Besonderheiten NNP cord-015369-72cjogxz 6442 12 zeigten zeigten NNP cord-015369-72cjogxz 6442 13 . . . cord-015369-72cjogxz 6443 1 Ein Ein NNP cord-015369-72cjogxz 6443 2 durchgeführtes durchgeführte NNS cord-015369-72cjogxz 6444 1 PET pet JJ cord-015369-72cjogxz 6444 2 CT CT NNP cord-015369-72cjogxz 6444 3 ergab ergab NN cord-015369-72cjogxz 6444 4 keinen keinen NNP cord-015369-72cjogxz 6444 5 keinen keinen NNP cord-015369-72cjogxz 6444 6 pathologischen pathologischen NNP cord-015369-72cjogxz 6444 7 FDG FDG NNP cord-015369-72cjogxz 6444 8 Uptake Uptake NNP cord-015369-72cjogxz 6444 9 , , , cord-015369-72cjogxz 6444 10 allerdings allerdings NNP cord-015369-72cjogxz 6444 11 eine eine NNP cord-015369-72cjogxz 6444 12 Raumforderung Raumforderung NNP cord-015369-72cjogxz 6444 13 beziehungsweise beziehungsweise NNP cord-015369-72cjogxz 6445 1 ein ein NNP cord-015369-72cjogxz 6445 2 fragliches fragliches NNP cord-015369-72cjogxz 6446 1 Hämatom Hämatom NNP cord-015369-72cjogxz 6447 1 i i PRP cord-015369-72cjogxz 6448 1 m m LS cord-015369-72cjogxz 6449 1 Bereich Bereich NNP cord-015369-72cjogxz 6449 2 des des FW cord-015369-72cjogxz 6449 3 rechten rechten NNP cord-015369-72cjogxz 6450 1 Lungenunterlappens Lungenunterlappens NNP cord-015369-72cjogxz 6450 2 sowie sowie NNP cord-015369-72cjogxz 6450 3 den den NN cord-015369-72cjogxz 6450 4 bekannten bekannten NNP cord-015369-72cjogxz 6450 5 Erguss Erguss NNP cord-015369-72cjogxz 6450 6 . . . cord-015369-72cjogxz 6451 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6451 2 . . . cord-015369-72cjogxz 6452 1 Zur Zur NNP cord-015369-72cjogxz 6452 2 weiteren weiteren NNP cord-015369-72cjogxz 6452 3 Abklärung Abklärung NNP cord-015369-72cjogxz 6452 4 führten führten NNP cord-015369-72cjogxz 6453 1 wir wir NNP cord-015369-72cjogxz 6453 2 eine eine NNP cord-015369-72cjogxz 6454 1 Videoassistierte Videoassistierte NNP cord-015369-72cjogxz 6454 2 Thorakoskopie Thorakoskopie NNP cord-015369-72cjogxz 6454 3 ( ( -LRB- cord-015369-72cjogxz 6454 4 VAT VAT NNP cord-015369-72cjogxz 6454 5 ) ) -RRB- cord-015369-72cjogxz 6454 6 durch durch NNP cord-015369-72cjogxz 6454 7 . . . cord-015369-72cjogxz 6455 1 Nach Nach NNP cord-015369-72cjogxz 6455 2 endoskopischer endoskopischer NNP cord-015369-72cjogxz 6455 3 Absaugung Absaugung NNP cord-015369-72cjogxz 6455 4 der der NNP cord-015369-72cjogxz 6455 5 Flüssigkeit Flüssigkeit NNP cord-015369-72cjogxz 6455 6 konnte konnte NNP cord-015369-72cjogxz 6455 7 ein ein NNP cord-015369-72cjogxz 6455 8 solitärer solitärer NN cord-015369-72cjogxz 6455 9 Tumor Tumor NNP cord-015369-72cjogxz 6455 10 , , , cord-015369-72cjogxz 6455 11 ausgehend ausgehend NNP cord-015369-72cjogxz 6455 12 vom vom NNP cord-015369-72cjogxz 6455 13 rechten rechten NNP cord-015369-72cjogxz 6455 14 Lungenunterlappen Lungenunterlappen NNP cord-015369-72cjogxz 6455 15 identifiziert identifiziert NNP cord-015369-72cjogxz 6455 16 werden werden NNP cord-015369-72cjogxz 6455 17 . . . cord-015369-72cjogxz 6456 1 Die die VB cord-015369-72cjogxz 6456 2 Resektion Resektion NNP cord-015369-72cjogxz 6456 3 gestaltete gestaltete NN cord-015369-72cjogxz 6456 4 sich sich NNP cord-015369-72cjogxz 6456 5 technisch technisch NNP cord-015369-72cjogxz 6456 6 einfach einfach NNP cord-015369-72cjogxz 6456 7 . . . cord-015369-72cjogxz 6457 1 Der Der NNP cord-015369-72cjogxz 6457 2 pathologische pathologische NN cord-015369-72cjogxz 6458 1 Befund Befund NNP cord-015369-72cjogxz 6458 2 zeigte zeigte NNP cord-015369-72cjogxz 6458 3 einen einen JJ cord-015369-72cjogxz 6458 4 fibrösen fibrösen NNP cord-015369-72cjogxz 6458 5 Pleuratumor Pleuratumor NNP cord-015369-72cjogxz 6458 6 ohne ohne NNP cord-015369-72cjogxz 6458 7 Malignität Malignität NNP cord-015369-72cjogxz 6459 1 ausgehend ausgehend NNP cord-015369-72cjogxz 6459 2 von von NNP cord-015369-72cjogxz 6459 3 der der NNP cord-015369-72cjogxz 6460 1 Pleura Pleura NNP cord-015369-72cjogxz 6460 2 viszeralis viszeralis NNP cord-015369-72cjogxz 6460 3 mit mit NNP cord-015369-72cjogxz 6460 4 einer einer NNP cord-015369-72cjogxz 6460 5 Größenausdehnung Größenausdehnung NNP cord-015369-72cjogxz 6460 6 von von NNP cord-015369-72cjogxz 6460 7 10,5:8,5:5,5 10,5:8,5:5,5 CD cord-015369-72cjogxz 6460 8 cm cm NNS cord-015369-72cjogxz 6460 9 . . . cord-015369-72cjogxz 6461 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6461 2 . . . cord-015369-72cjogxz 6462 1 Benigne Benigne NNP cord-015369-72cjogxz 6462 2 fibröse fibröse NNP cord-015369-72cjogxz 6463 1 Tumoren Tumoren NNP cord-015369-72cjogxz 6463 2 der der NNP cord-015369-72cjogxz 6463 3 Pleura Pleura NNP cord-015369-72cjogxz 6463 4 sind sind NNP cord-015369-72cjogxz 6463 5 selten selten NNP cord-015369-72cjogxz 6463 6 . . . cord-015369-72cjogxz 6464 1 Eine Eine NNP cord-015369-72cjogxz 6464 2 chirurgische chirurgische NN cord-015369-72cjogxz 6464 3 Resektion Resektion NNP cord-015369-72cjogxz 6464 4 sollte sollte NNP cord-015369-72cjogxz 6464 5 angestrebt angestrebt NNP cord-015369-72cjogxz 6464 6 werden werden NNP cord-015369-72cjogxz 6464 7 , , , cord-015369-72cjogxz 6464 8 Rezidive Rezidive NNP cord-015369-72cjogxz 6464 9 werden werden NNP cord-015369-72cjogxz 6464 10 kaum kaum NNP cord-015369-72cjogxz 6464 11 beschrieben beschrieben NNP cord-015369-72cjogxz 6464 12 . . . cord-015369-72cjogxz 6465 1 Indikation Indikation NNP cord-015369-72cjogxz 6465 2 zur zur NNP cord-015369-72cjogxz 6466 1 onkologischen onkologischen NNP cord-015369-72cjogxz 6467 1 Resektion Resektion NNP cord-015369-72cjogxz 6467 2 und und IN cord-015369-72cjogxz 6467 3 Lymphknotendissektion Lymphknotendissektion NNP cord-015369-72cjogxz 6467 4 bei bei NNP cord-015369-72cjogxz 6467 5 ACTHsezernierendem ACTHsezernierendem NNP cord-015369-72cjogxz 6467 6 NET NET NNP cord-015369-72cjogxz 6467 7 der der NN cord-015369-72cjogxz 6467 8 Lunge Lunge NNP cord-015369-72cjogxz 6467 9 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6467 10 . . . cord-015369-72cjogxz 6468 1 Nach Nach NNP cord-015369-72cjogxz 6468 2 histologischem histologischem NNP cord-015369-72cjogxz 6469 1 Nachweis Nachweis NNP cord-015369-72cjogxz 6469 2 eines eine NNS cord-015369-72cjogxz 6469 3 ACTHexprimierenden acthexprimierenden JJ cord-015369-72cjogxz 6469 4 malignen malignen NNP cord-015369-72cjogxz 6470 1 neuroendokrinen neuroendokrinen NNP cord-015369-72cjogxz 6470 2 Tumors Tumors NNPS cord-015369-72cjogxz 6470 3 mittels mittels NNPS cord-015369-72cjogxz 6470 4 thorakoskopischer thorakoskopischer XX cord-015369-72cjogxz 6471 1 Lungen Lungen NNP cord-015369-72cjogxz 6471 2 - - HYPH cord-015369-72cjogxz 6471 3 Wedgeresektion Wedgeresektion NNP cord-015369-72cjogxz 6471 4 wird wird NNP cord-015369-72cjogxz 6471 5 die die VBP cord-015369-72cjogxz 6472 1 Indikation Indikation NNP cord-015369-72cjogxz 6472 2 zur zur NNP cord-015369-72cjogxz 6473 1 onkologischen onkologischen NNP cord-015369-72cjogxz 6473 2 Lungenresektion Lungenresektion NNP cord-015369-72cjogxz 6473 3 mit mit NNP cord-015369-72cjogxz 6473 4 mediastinaler mediastinaler NNP cord-015369-72cjogxz 6474 1 Lymphadenektomie Lymphadenektomie NNP cord-015369-72cjogxz 6474 2 anhand anhand NNP cord-015369-72cjogxz 6474 3 eines eines NNP cord-015369-72cjogxz 6474 4 Fallberichtes Fallberichtes NNP cord-015369-72cjogxz 6474 5 diskutiert diskutiert NNP cord-015369-72cjogxz 6474 6 . . . cord-015369-72cjogxz 6475 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6475 2 . . . cord-015369-72cjogxz 6476 1 Ein Ein NNP cord-015369-72cjogxz 6476 2 29 29 CD cord-015369-72cjogxz 6476 3 jähriger jähriger NN cord-015369-72cjogxz 6476 4 Patient Patient NNP cord-015369-72cjogxz 6476 5 mit mit NNP cord-015369-72cjogxz 6476 6 dem dem NNP cord-015369-72cjogxz 6476 7 klassischen klassischen NNP cord-015369-72cjogxz 6476 8 Bild Bild NNP cord-015369-72cjogxz 6477 1 eines eines NNP cord-015369-72cjogxz 6477 2 zentralen zentralen NNP cord-015369-72cjogxz 6478 1 Morbus Morbus NNP cord-015369-72cjogxz 6478 2 Cushing Cushing NNP cord-015369-72cjogxz 6478 3 wies wies NNP cord-015369-72cjogxz 6478 4 bei bei NNP cord-015369-72cjogxz 6478 5 unauffälliger unauffälliger NNP cord-015369-72cjogxz 6479 1 craniocerebraler craniocerebraler NNP cord-015369-72cjogxz 6479 2 Magnetresonanztomographie Magnetresonanztomographie NNP cord-015369-72cjogxz 6479 3 in in IN cord-015369-72cjogxz 6479 4 der der NNP cord-015369-72cjogxz 6479 5 thora thora NNP cord-015369-72cjogxz 6480 1 -duced -duced JJ cord-015369-72cjogxz 6480 2 by by IN cord-015369-72cjogxz 6480 3 pulmonary pulmonary JJ cord-015369-72cjogxz 6480 4 vascular vascular JJ cord-015369-72cjogxz 6480 5 endothelial endothelial JJ cord-015369-72cjogxz 6480 6 cells cell NNS cord-015369-72cjogxz 6480 7 , , , cord-015369-72cjogxz 6480 8 playing play VBG cord-015369-72cjogxz 6480 9 a a DT cord-015369-72cjogxz 6480 10 role role NN cord-015369-72cjogxz 6480 11 in in IN cord-015369-72cjogxz 6480 12 the the DT cord-015369-72cjogxz 6480 13 pathophysiology pathophysiology NN cord-015369-72cjogxz 6480 14 of of IN cord-015369-72cjogxz 6480 15 pulmonary pulmonary JJ cord-015369-72cjogxz 6480 16 edema edema NN cord-015369-72cjogxz 6480 17 . . . cord-015369-72cjogxz 6481 1 Whether whether IN cord-015369-72cjogxz 6481 2 pretransplant pretransplant JJ cord-015369-72cjogxz 6481 3 pulmonary pulmonary JJ cord-015369-72cjogxz 6481 4 tissue tissue NN cord-015369-72cjogxz 6482 1 ET-1 ET-1 NNP cord-015369-72cjogxz 6482 2 mRNA mRNA NNP cord-015369-72cjogxz 6482 3 could could MD cord-015369-72cjogxz 6482 4 predict predict VB cord-015369-72cjogxz 6482 5 PGD PGD NNP cord-015369-72cjogxz 6482 6 in in IN cord-015369-72cjogxz 6482 7 LTX LTX NNP cord-015369-72cjogxz 6482 8 is be VBZ cord-015369-72cjogxz 6482 9 unknown unknown JJ cord-015369-72cjogxz 6482 10 . . . cord-015369-72cjogxz 6483 1 ET-1 ET-1 NNP cord-015369-72cjogxz 6483 2 mRNA mRNA NNP cord-015369-72cjogxz 6483 3 expression expression NN cord-015369-72cjogxz 6483 4 was be VBD cord-015369-72cjogxz 6483 5 examined examine VBN cord-015369-72cjogxz 6483 6 by by IN cord-015369-72cjogxz 6483 7 real real JJ cord-015369-72cjogxz 6483 8 time time NN cord-015369-72cjogxz 6483 9 RT RT NNP cord-015369-72cjogxz 6483 10 - - HYPH cord-015369-72cjogxz 6483 11 PCR PCR NNP cord-015369-72cjogxz 6483 12 in in IN cord-015369-72cjogxz 6483 13 lung lung NN cord-015369-72cjogxz 6483 14 tissue tissue NN cord-015369-72cjogxz 6483 15 biopsies biopsy NNS cord-015369-72cjogxz 6483 16 of of IN cord-015369-72cjogxz 6483 17 50 50 CD cord-015369-72cjogxz 6483 18 donors donor NNS cord-015369-72cjogxz 6483 19 ( ( -LRB- cord-015369-72cjogxz 6483 20 mean mean VB cord-015369-72cjogxz 6483 21 age age NN cord-015369-72cjogxz 6483 22 39 39 CD cord-015369-72cjogxz 6483 23 AE AE NNP cord-015369-72cjogxz 6483 24 13 13 CD cord-015369-72cjogxz 6483 25 years year NNS cord-015369-72cjogxz 6483 26 ) ) -RRB- cord-015369-72cjogxz 6483 27 and and CC cord-015369-72cjogxz 6483 28 recipients recipient NNS cord-015369-72cjogxz 6483 29 ( ( -LRB- cord-015369-72cjogxz 6483 30 mean mean VB cord-015369-72cjogxz 6483 31 age age NN cord-015369-72cjogxz 6483 32 48 48 CD cord-015369-72cjogxz 6483 33 AE AE NNP cord-015369-72cjogxz 6483 34 13 13 CD cord-015369-72cjogxz 6483 35 years year NNS cord-015369-72cjogxz 6483 36 ) ) -RRB- cord-015369-72cjogxz 6483 37 obtained obtain VBN cord-015369-72cjogxz 6483 38 shortly shortly RB cord-015369-72cjogxz 6483 39 before before IN cord-015369-72cjogxz 6483 40 LTX LTX NNP cord-015369-72cjogxz 6483 41 . . . cord-015369-72cjogxz 6484 1 The the DT cord-015369-72cjogxz 6484 2 mean mean JJ cord-015369-72cjogxz 6484 3 ischemic ischemic JJ cord-015369-72cjogxz 6484 4 time time NN cord-015369-72cjogxz 6484 5 of of IN cord-015369-72cjogxz 6484 6 the the DT cord-015369-72cjogxz 6484 7 graft graft NN cord-015369-72cjogxz 6484 8 was be VBD cord-015369-72cjogxz 6484 9 295 295 CD cord-015369-72cjogxz 6484 10 AE AE NNP cord-015369-72cjogxz 6484 11 59 59 CD cord-015369-72cjogxz 6484 12 Minutes minute NNS cord-015369-72cjogxz 6484 13 . . . cord-015369-72cjogxz 6485 1 The the DT cord-015369-72cjogxz 6485 2 underlying underlie VBG cord-015369-72cjogxz 6485 3 disease disease NN cord-015369-72cjogxz 6485 4 in in IN cord-015369-72cjogxz 6485 5 recipients recipient NNS cord-015369-72cjogxz 6485 6 was be VBD cord-015369-72cjogxz 6485 7 chronic chronic JJ cord-015369-72cjogxz 6485 8 obstructive obstructive JJ cord-015369-72cjogxz 6485 9 pulmonary pulmonary JJ cord-015369-72cjogxz 6485 10 disease disease NN cord-015369-72cjogxz 6485 11 ( ( -LRB- cord-015369-72cjogxz 6485 12 n n NN cord-015369-72cjogxz 6485 13 ¼ ¼ NNP cord-015369-72cjogxz 6485 14 28 28 CD cord-015369-72cjogxz 6485 15 ) ) -RRB- cord-015369-72cjogxz 6485 16 , , , cord-015369-72cjogxz 6485 17 cystic cystic JJ cord-015369-72cjogxz 6485 18 fibrosis fibrosis NN cord-015369-72cjogxz 6485 19 ( ( -LRB- cord-015369-72cjogxz 6485 20 n n NNP cord-015369-72cjogxz 6485 21 ¼ ¼ NNP cord-015369-72cjogxz 6485 22 9 9 CD cord-015369-72cjogxz 6485 23 ) ) -RRB- cord-015369-72cjogxz 6485 24 , , , cord-015369-72cjogxz 6485 25 emphysema emphysema NN cord-015369-72cjogxz 6485 26 ( ( -LRB- cord-015369-72cjogxz 6485 27 n n NN cord-015369-72cjogxz 6485 28 ¼ ¼ NNP cord-015369-72cjogxz 6485 29 9 9 CD cord-015369-72cjogxz 6485 30 ) ) -RRB- cord-015369-72cjogxz 6485 31 , , , cord-015369-72cjogxz 6485 32 primary primary JJ cord-015369-72cjogxz 6485 33 pulmonary pulmonary JJ cord-015369-72cjogxz 6485 34 hypertension hypertension NN cord-015369-72cjogxz 6485 35 ( ( -LRB- cord-015369-72cjogxz 6485 36 n n NNP cord-015369-72cjogxz 6485 37 ¼ ¼ NNP cord-015369-72cjogxz 6485 38 1 1 CD cord-015369-72cjogxz 6485 39 ) ) -RRB- cord-015369-72cjogxz 6485 40 and and CC cord-015369-72cjogxz 6485 41 retransplantation retransplantation NNP cord-015369-72cjogxz 6485 42 ( ( -LRB- cord-015369-72cjogxz 6485 43 n n CC cord-015369-72cjogxz 6485 44 ¼ ¼ NNP cord-015369-72cjogxz 6485 45 3 3 CD cord-015369-72cjogxz 6485 46 ) ) -RRB- cord-015369-72cjogxz 6485 47 . . . cord-015369-72cjogxz 6486 1 In in IN cord-015369-72cjogxz 6486 2 28 28 CD cord-015369-72cjogxz 6486 3 % % NN cord-015369-72cjogxz 6486 4 of of IN cord-015369-72cjogxz 6486 5 patients patient NNS cord-015369-72cjogxz 6486 6 , , , cord-015369-72cjogxz 6486 7 PGD PGD NNP cord-015369-72cjogxz 6486 8 was be VBD cord-015369-72cjogxz 6486 9 diagnosed diagnose VBN cord-015369-72cjogxz 6486 10 and and CC cord-015369-72cjogxz 6486 11 scored score VBN cord-015369-72cjogxz 6486 12 by by IN cord-015369-72cjogxz 6486 13 oxygenation oxygenation NN cord-015369-72cjogxz 6486 14 and and CC cord-015369-72cjogxz 6486 15 radiological radiological JJ cord-015369-72cjogxz 6486 16 characteristics characteristic NNS cord-015369-72cjogxz 6486 17 according accord VBG cord-015369-72cjogxz 6486 18 to to IN cord-015369-72cjogxz 6486 19 ISHLT ISHLT NNP cord-015369-72cjogxz 6486 20 guidelines guideline NNS cord-015369-72cjogxz 6486 21 . . . cord-015369-72cjogxz 6487 1 Expression expression NN cord-015369-72cjogxz 6487 2 levels level NNS cord-015369-72cjogxz 6487 3 of of IN cord-015369-72cjogxz 6487 4 ET-1 ET-1 NNP cord-015369-72cjogxz 6487 5 mRNA mRNA NNP cord-015369-72cjogxz 6487 6 were be VBD cord-015369-72cjogxz 6487 7 significantly significantly RB cord-015369-72cjogxz 6487 8 increased increase VBN cord-015369-72cjogxz 6487 9 in in IN cord-015369-72cjogxz 6487 10 both both DT cord-015369-72cjogxz 6487 11 donor donor NN cord-015369-72cjogxz 6487 12 ( ( -LRB- cord-015369-72cjogxz 6487 13 p p NN cord-015369-72cjogxz 6487 14 < < XX cord-015369-72cjogxz 6487 15 0.01 0.01 CD cord-015369-72cjogxz 6487 16 ) ) -RRB- cord-015369-72cjogxz 6487 17 and and CC cord-015369-72cjogxz 6487 18 recipient recipient NN cord-015369-72cjogxz 6487 19 ( ( -LRB- cord-015369-72cjogxz 6487 20 p p NN cord-015369-72cjogxz 6487 21 < < XX cord-015369-72cjogxz 6487 22 0.03 0.03 CD cord-015369-72cjogxz 6487 23 ) ) -RRB- cord-015369-72cjogxz 6487 24 tissue tissue NN cord-015369-72cjogxz 6487 25 in in IN cord-015369-72cjogxz 6487 26 the the DT cord-015369-72cjogxz 6487 27 patient patient NN cord-015369-72cjogxz 6487 28 group group NN cord-015369-72cjogxz 6487 29 developing develop VBG cord-015369-72cjogxz 6487 30 PGD PGD NNP cord-015369-72cjogxz 6487 31 . . . cord-015369-72cjogxz 6488 1 Moreover moreover RB cord-015369-72cjogxz 6488 2 , , , cord-015369-72cjogxz 6488 3 donor donor NN cord-015369-72cjogxz 6488 4 and and CC cord-015369-72cjogxz 6488 5 recipient recipient NN cord-015369-72cjogxz 6488 6 ET-1 ET-1 NNP cord-015369-72cjogxz 6488 7 gene gene NN cord-015369-72cjogxz 6488 8 expression expression NN cord-015369-72cjogxz 6488 9 correlated correlate VBN cord-015369-72cjogxz 6488 10 with with IN cord-015369-72cjogxz 6488 11 the the DT cord-015369-72cjogxz 6488 12 grading grading NN cord-015369-72cjogxz 6488 13 of of IN cord-015369-72cjogxz 6488 14 PGD PGD NNP cord-015369-72cjogxz 6488 15 severity severity NN cord-015369-72cjogxz 6488 16 ( ( -LRB- cord-015369-72cjogxz 6488 17 r r NNP cord-015369-72cjogxz 6488 18 s s NNP cord-015369-72cjogxz 6488 19 ¼ ¼ NNP cord-015369-72cjogxz 6488 20 0.56 0.56 CD cord-015369-72cjogxz 6488 21 ; ; : cord-015369-72cjogxz 6488 22 p p NN cord-015369-72cjogxz 6488 23 < < XX cord-015369-72cjogxz 6488 24 0.01 0.01 CD cord-015369-72cjogxz 6488 25 ) ) -RRB- cord-015369-72cjogxz 6488 26 . . . cord-015369-72cjogxz 6489 1 Neither neither CC cord-015369-72cjogxz 6489 2 PGD PGD NNP cord-015369-72cjogxz 6489 3 grade grade NN cord-015369-72cjogxz 6489 4 nor nor CC cord-015369-72cjogxz 6489 5 ET-1 ET-1 NNP cord-015369-72cjogxz 6489 6 expression expression NN cord-015369-72cjogxz 6489 7 correlated correlate VBD cord-015369-72cjogxz 6489 8 to to IN cord-015369-72cjogxz 6489 9 patient patient NN cord-015369-72cjogxz 6489 10 age age NN cord-015369-72cjogxz 6489 11 or or CC cord-015369-72cjogxz 6489 12 ischemia ischemia NN cord-015369-72cjogxz 6489 13 time time NN cord-015369-72cjogxz 6489 14 of of IN cord-015369-72cjogxz 6489 15 the the DT cord-015369-72cjogxz 6489 16 graft graft NN cord-015369-72cjogxz 6489 17 . . . cord-015369-72cjogxz 6490 1 This this DT cord-015369-72cjogxz 6490 2 study study NN cord-015369-72cjogxz 6490 3 indicates indicate VBZ cord-015369-72cjogxz 6490 4 for for IN cord-015369-72cjogxz 6490 5 the the DT cord-015369-72cjogxz 6490 6 first first JJ cord-015369-72cjogxz 6490 7 time time NN cord-015369-72cjogxz 6490 8 that that WDT cord-015369-72cjogxz 6490 9 pre pre JJ cord-015369-72cjogxz 6490 10 - - NN cord-015369-72cjogxz 6490 11 transplant transplant NN cord-015369-72cjogxz 6490 12 ET-1 ET-1 NNP cord-015369-72cjogxz 6490 13 mRNA mRNA NNP cord-015369-72cjogxz 6490 14 overexpression overexpression NN cord-015369-72cjogxz 6490 15 in in IN cord-015369-72cjogxz 6490 16 both both CC cord-015369-72cjogxz 6490 17 donor donor NN cord-015369-72cjogxz 6490 18 and and CC cord-015369-72cjogxz 6490 19 recipient recipient NN cord-015369-72cjogxz 6490 20 mediates mediate VBZ cord-015369-72cjogxz 6490 21 PGD PGD NNP cord-015369-72cjogxz 6490 22 development development NN cord-015369-72cjogxz 6490 23 due due IN cord-015369-72cjogxz 6490 24 to to IN cord-015369-72cjogxz 6490 25 alteration alteration NN cord-015369-72cjogxz 6490 26 of of IN cord-015369-72cjogxz 6490 27 pulmonary pulmonary JJ cord-015369-72cjogxz 6490 28 vascular vascular JJ cord-015369-72cjogxz 6490 29 resistance resistance NN cord-015369-72cjogxz 6490 30 and and CC cord-015369-72cjogxz 6490 31 permeability permeability NN cord-015369-72cjogxz 6490 32 . . . cord-015369-72cjogxz 6491 1 Assessment assessment NN cord-015369-72cjogxz 6491 2 of of IN cord-015369-72cjogxz 6491 3 ET-1 ET-1 NNP cord-015369-72cjogxz 6491 4 tissue tissue NN cord-015369-72cjogxz 6491 5 gene gene NN cord-015369-72cjogxz 6491 6 expression expression NN cord-015369-72cjogxz 6491 7 is be VBZ cord-015369-72cjogxz 6491 8 thus thus RB cord-015369-72cjogxz 6491 9 a a DT cord-015369-72cjogxz 6491 10 sensitive sensitive JJ cord-015369-72cjogxz 6491 11 and and CC cord-015369-72cjogxz 6491 12 specific specific JJ cord-015369-72cjogxz 6491 13 predictor predictor NN cord-015369-72cjogxz 6491 14 of of IN cord-015369-72cjogxz 6491 15 PGD PGD NNP cord-015369-72cjogxz 6491 16 in in IN cord-015369-72cjogxz 6491 17 LTX LTX NNP cord-015369-72cjogxz 6491 18 and and CC cord-015369-72cjogxz 6491 19 might may MD cord-015369-72cjogxz 6491 20 be be VB cord-015369-72cjogxz 6491 21 beneficial beneficial JJ cord-015369-72cjogxz 6491 22 in in IN cord-015369-72cjogxz 6491 23 donor donor NN cord-015369-72cjogxz 6491 24 selection selection NN cord-015369-72cjogxz 6491 25 and and CC cord-015369-72cjogxz 6491 26 in in IN cord-015369-72cjogxz 6491 27 the the DT cord-015369-72cjogxz 6491 28 prophylactic prophylactic JJ cord-015369-72cjogxz 6491 29 treatment treatment NN cord-015369-72cjogxz 6491 30 of of IN cord-015369-72cjogxz 6491 31 recipients recipient NNS cord-015369-72cjogxz 6491 32 by by IN cord-015369-72cjogxz 6491 33 using use VBG cord-015369-72cjogxz 6491 34 targeted target VBN cord-015369-72cjogxz 6491 35 ET-1 ET-1 NNP cord-015369-72cjogxz 6491 36 antagonists antagonist NNS cord-015369-72cjogxz 6491 37 . . . cord-015369-72cjogxz 6492 1 surgical surgical JJ cord-015369-72cjogxz 6492 2 closure closure NN cord-015369-72cjogxz 6492 3 of of IN cord-015369-72cjogxz 6492 4 the the DT cord-015369-72cjogxz 6492 5 ASD ASD NNP cord-015369-72cjogxz 6492 6 was be VBD cord-015369-72cjogxz 6492 7 possible possible JJ cord-015369-72cjogxz 6492 8 with with IN cord-015369-72cjogxz 6492 9 near near RB cord-015369-72cjogxz 6492 10 - - HYPH cord-015369-72cjogxz 6492 11 normalized normalized JJ cord-015369-72cjogxz 6492 12 PAPs pap NNS cord-015369-72cjogxz 6492 13 after after IN cord-015369-72cjogxz 6492 14 ten ten CD cord-015369-72cjogxz 6492 15 months month NNS cord-015369-72cjogxz 6492 16 of of IN cord-015369-72cjogxz 6492 17 ' ' '' cord-015369-72cjogxz 6492 18 ' ' `` cord-015369-72cjogxz 6492 19 conditioning conditioning NN cord-015369-72cjogxz 6492 20 ' ' '' cord-015369-72cjogxz 6492 21 ' ' '' cord-015369-72cjogxz 6492 22 medication medication NN cord-015369-72cjogxz 6492 23 with with IN cord-015369-72cjogxz 6492 24 bosentan bosentan NNP cord-015369-72cjogxz 6492 25 ( ( -LRB- cord-015369-72cjogxz 6492 26 250 250 CD cord-015369-72cjogxz 6492 27 mg mg NNP cord-015369-72cjogxz 6492 28 / / SYM cord-015369-72cjogxz 6492 29 day day NN cord-015369-72cjogxz 6492 30 ) ) -RRB- cord-015369-72cjogxz 6492 31 . . . cord-015369-72cjogxz 6493 1 The the DT cord-015369-72cjogxz 6493 2 patient patient NN cord-015369-72cjogxz 6493 3 could could MD cord-015369-72cjogxz 6493 4 be be VB cord-015369-72cjogxz 6493 5 discharged discharge VBN cord-015369-72cjogxz 6493 6 from from IN cord-015369-72cjogxz 6493 7 the the DT cord-015369-72cjogxz 6493 8 hospital hospital NN cord-015369-72cjogxz 6493 9 on on IN cord-015369-72cjogxz 6493 10 post post JJ cord-015369-72cjogxz 6493 11 - - JJ cord-015369-72cjogxz 6493 12 operative operative JJ cord-015369-72cjogxz 6493 13 day day NN cord-015369-72cjogxz 6493 14 28 28 CD cord-015369-72cjogxz 6493 15 under under IN cord-015369-72cjogxz 6493 16 ongoing ongoing JJ cord-015369-72cjogxz 6493 17 bosentan bosentan JJ cord-015369-72cjogxz 6493 18 treatment treatment NN cord-015369-72cjogxz 6493 19 . . . cord-015369-72cjogxz 6494 1 Eight eight CD cord-015369-72cjogxz 6494 2 months month NNS cord-015369-72cjogxz 6494 3 thereafter thereafter RB cord-015369-72cjogxz 6494 4 the the DT cord-015369-72cjogxz 6494 5 patient patient NN cord-015369-72cjogxz 6494 6 was be VBD cord-015369-72cjogxz 6494 7 in in IN cord-015369-72cjogxz 6494 8 good good JJ cord-015369-72cjogxz 6494 9 clinical clinical JJ cord-015369-72cjogxz 6494 10 condition condition NN cord-015369-72cjogxz 6494 11 with with IN cord-015369-72cjogxz 6494 12 residual residual JJ cord-015369-72cjogxz 6494 13 mild mild JJ cord-015369-72cjogxz 6494 14 pulmonary pulmonary JJ cord-015369-72cjogxz 6494 15 hypertension hypertension NN cord-015369-72cjogxz 6494 16 . . . cord-015369-72cjogxz 6495 1 The the DT cord-015369-72cjogxz 6495 2 traditional traditional JJ cord-015369-72cjogxz 6495 3 rule rule NN cord-015369-72cjogxz 6495 4 of of IN cord-015369-72cjogxz 6495 5 inoperability inoperability NN cord-015369-72cjogxz 6495 6 of of IN cord-015369-72cjogxz 6495 7 an an DT cord-015369-72cjogxz 6495 8 ASD asd NN cord-015369-72cjogxz 6495 9 with with IN cord-015369-72cjogxz 6495 10 severe severe JJ cord-015369-72cjogxz 6495 11 pulmonary pulmonary JJ cord-015369-72cjogxz 6495 12 hypertension hypertension NN cord-015369-72cjogxz 6495 13 was be VBD cord-015369-72cjogxz 6495 14 recently recently RB cord-015369-72cjogxz 6495 15 challenged challenge VBN cord-015369-72cjogxz 6495 16 by by IN cord-015369-72cjogxz 6495 17 case case NN cord-015369-72cjogxz 6495 18 reports report NNS cord-015369-72cjogxz 6495 19 where where WRB cord-015369-72cjogxz 6495 20 ASD ASD NNP cord-015369-72cjogxz 6495 21 could could MD cord-015369-72cjogxz 6495 22 be be VB cord-015369-72cjogxz 6495 23 closed close VBN cord-015369-72cjogxz 6495 24 after after IN cord-015369-72cjogxz 6495 25 long long JJ cord-015369-72cjogxz 6495 26 - - HYPH cord-015369-72cjogxz 6495 27 time time NN cord-015369-72cjogxz 6495 28 conditioning conditioning NN cord-015369-72cjogxz 6495 29 therapy therapy NN cord-015369-72cjogxz 6495 30 with with IN cord-015369-72cjogxz 6495 31 prostacycline prostacycline NNP cord-015369-72cjogxz 6495 32 . . . cord-015369-72cjogxz 6496 1 We -PRON- PRP cord-015369-72cjogxz 6496 2 now now RB cord-015369-72cjogxz 6496 3 present present VBP cord-015369-72cjogxz 6496 4 a a DT cord-015369-72cjogxz 6496 5 similar similar JJ cord-015369-72cjogxz 6496 6 case case NN cord-015369-72cjogxz 6496 7 treated treat VBN cord-015369-72cjogxz 6496 8 with with IN cord-015369-72cjogxz 6496 9 bosentan bosentan NNP cord-015369-72cjogxz 6496 10 ( ( -LRB- cord-015369-72cjogxz 6496 11 an an DT cord-015369-72cjogxz 6496 12 endothelin endothelin JJ cord-015369-72cjogxz 6496 13 antagonist antagonist NN cord-015369-72cjogxz 6496 14 ) ) -RRB- cord-015369-72cjogxz 6496 15 , , , cord-015369-72cjogxz 6496 16 which which WDT cord-015369-72cjogxz 6496 17 has have VBZ cord-015369-72cjogxz 6496 18 several several JJ cord-015369-72cjogxz 6496 19 advantages advantage NNS cord-015369-72cjogxz 6496 20 compared compare VBN cord-015369-72cjogxz 6496 21 to to IN cord-015369-72cjogxz 6496 22 epoprostenol epoprostenol NNP cord-015369-72cjogxz 6496 23 . . . cord-015369-72cjogxz 6497 1 Because because IN cord-015369-72cjogxz 6497 2 it -PRON- PRP cord-015369-72cjogxz 6497 3 is be VBZ cord-015369-72cjogxz 6497 4 an an DT cord-015369-72cjogxz 6497 5 oral oral JJ cord-015369-72cjogxz 6497 6 drug drug NN cord-015369-72cjogxz 6497 7 , , , cord-015369-72cjogxz 6497 8 there there EX cord-015369-72cjogxz 6497 9 are be VBP cord-015369-72cjogxz 6497 10 no no DT cord-015369-72cjogxz 6497 11 complications complication NNS cord-015369-72cjogxz 6497 12 related relate VBN cord-015369-72cjogxz 6497 13 to to IN cord-015369-72cjogxz 6497 14 an an DT cord-015369-72cjogxz 6497 15 intravenous intravenous JJ cord-015369-72cjogxz 6497 16 delivery delivery NN cord-015369-72cjogxz 6497 17 system system NN cord-015369-72cjogxz 6497 18 which which WDT cord-015369-72cjogxz 6497 19 are be VBP cord-015369-72cjogxz 6497 20 common common JJ cord-015369-72cjogxz 6497 21 under under IN cord-015369-72cjogxz 6497 22 long long JJ cord-015369-72cjogxz 6497 23 - - HYPH cord-015369-72cjogxz 6497 24 time time NN cord-015369-72cjogxz 6497 25 prostaglandin prostaglandin NN cord-015369-72cjogxz 6497 26 therapy therapy NN cord-015369-72cjogxz 6497 27 . . . cord-015369-72cjogxz 6498 1 We -PRON- PRP cord-015369-72cjogxz 6498 2 conclude conclude VBP cord-015369-72cjogxz 6498 3 that that IN cord-015369-72cjogxz 6498 4 a a DT cord-015369-72cjogxz 6498 5 pre pre JJ cord-015369-72cjogxz 6498 6 - - JJ cord-015369-72cjogxz 6498 7 operative operative JJ cord-015369-72cjogxz 6498 8 bosentan bosentan JJ cord-015369-72cjogxz 6498 9 treatment treatment NN cord-015369-72cjogxz 6498 10 of of IN cord-015369-72cjogxz 6498 11 a a DT cord-015369-72cjogxz 6498 12 patient patient NN cord-015369-72cjogxz 6498 13 with with IN cord-015369-72cjogxz 6498 14 ASD ASD NNP cord-015369-72cjogxz 6498 15 II II NNP cord-015369-72cjogxz 6498 16 and and CC cord-015369-72cjogxz 6498 17 severe severe JJ cord-015369-72cjogxz 6498 18 PAH PAH NNP cord-015369-72cjogxz 6498 19 is be VBZ cord-015369-72cjogxz 6498 20 feasible feasible JJ cord-015369-72cjogxz 6498 21 and and CC cord-015369-72cjogxz 6498 22 may may MD cord-015369-72cjogxz 6498 23 allow allow VB cord-015369-72cjogxz 6498 24 surgical surgical JJ cord-015369-72cjogxz 6498 25 correction correction NN cord-015369-72cjogxz 6498 26 . . . cord-015369-72cjogxz 6499 1 lung lung NN cord-015369-72cjogxz 6499 2 compression compression NN cord-015369-72cjogxz 6499 3 and and CC cord-015369-72cjogxz 6499 4 cardiac cardiac JJ cord-015369-72cjogxz 6499 5 displacement displacement NN cord-015369-72cjogxz 6499 6 resulting result VBG cord-015369-72cjogxz 6499 7 from from IN cord-015369-72cjogxz 6499 8 the the DT cord-015369-72cjogxz 6499 9 caved cave VBN cord-015369-72cjogxz 6499 10 - - HYPH cord-015369-72cjogxz 6499 11 in in RP cord-015369-72cjogxz 6499 12 chest chest NN cord-015369-72cjogxz 6499 13 . . . cord-015369-72cjogxz 6500 1 In in IN cord-015369-72cjogxz 6500 2 the the DT cord-015369-72cjogxz 6500 3 second second JJ cord-015369-72cjogxz 6500 4 case case NN cord-015369-72cjogxz 6500 5 , , , cord-015369-72cjogxz 6500 6 a a DT cord-015369-72cjogxz 6500 7 40-year 40-year JJ cord-015369-72cjogxz 6500 8 - - HYPH cord-015369-72cjogxz 6500 9 old old JJ cord-015369-72cjogxz 6500 10 woman woman NN cord-015369-72cjogxz 6500 11 that that WDT cord-015369-72cjogxz 6500 12 received receive VBD cord-015369-72cjogxz 6500 13 chemotherapy chemotherapy NN cord-015369-72cjogxz 6500 14 for for IN cord-015369-72cjogxz 6500 15 an an DT cord-015369-72cjogxz 6500 16 aggressive aggressive JJ cord-015369-72cjogxz 6500 17 undifferentiated undifferentiated JJ cord-015369-72cjogxz 6500 18 tumor tumor NN cord-015369-72cjogxz 6500 19 of of IN cord-015369-72cjogxz 6500 20 the the DT cord-015369-72cjogxz 6500 21 sarcoma sarcoma NN cord-015369-72cjogxz 6500 22 group group NN cord-015369-72cjogxz 6500 23 , , , cord-015369-72cjogxz 6500 24 infiltrating infiltrate VBG cord-015369-72cjogxz 6500 25 clavicle clavicle NN cord-015369-72cjogxz 6500 26 , , , cord-015369-72cjogxz 6500 27 humeroclavicular humeroclavicular NNP cord-015369-72cjogxz 6500 28 and and CC cord-015369-72cjogxz 6500 29 acromial acromial JJ cord-015369-72cjogxz 6500 30 joints joint NNS cord-015369-72cjogxz 6500 31 , , , cord-015369-72cjogxz 6500 32 was be VBD cord-015369-72cjogxz 6500 33 chosen choose VBN cord-015369-72cjogxz 6500 34 for for IN cord-015369-72cjogxz 6500 35 forequarter forequarter NN cord-015369-72cjogxz 6500 36 amputation amputation NN cord-015369-72cjogxz 6500 37 with with IN cord-015369-72cjogxz 6500 38 resection resection NN cord-015369-72cjogxz 6500 39 of of IN cord-015369-72cjogxz 6500 40 thoracic thoracic JJ cord-015369-72cjogxz 6500 41 wall wall NN cord-015369-72cjogxz 6500 42 . . . cord-015369-72cjogxz 6501 1 Reconstruction reconstruction NN cord-015369-72cjogxz 6501 2 also also RB cord-015369-72cjogxz 6501 3 involved involve VBD cord-015369-72cjogxz 6501 4 a a DT cord-015369-72cjogxz 6501 5 myocutaneous myocutaneous JJ cord-015369-72cjogxz 6501 6 armflap armflap NNP cord-015369-72cjogxz 6501 7 . . . cord-015369-72cjogxz 6502 1 In in IN cord-015369-72cjogxz 6502 2 the the DT cord-015369-72cjogxz 6502 3 third third JJ cord-015369-72cjogxz 6502 4 case case NN cord-015369-72cjogxz 6502 5 , , , cord-015369-72cjogxz 6502 6 a a DT cord-015369-72cjogxz 6502 7 58-year 58-year JJ cord-015369-72cjogxz 6502 8 - - HYPH cord-015369-72cjogxz 6502 9 old old JJ cord-015369-72cjogxz 6502 10 woman woman NN cord-015369-72cjogxz 6502 11 with with IN cord-015369-72cjogxz 6502 12 a a DT cord-015369-72cjogxz 6502 13 chondrosarcoma chondrosarcoma NN cord-015369-72cjogxz 6502 14 of of IN cord-015369-72cjogxz 6502 15 the the DT cord-015369-72cjogxz 6502 16 sternum sternum NN cord-015369-72cjogxz 6502 17 underwent undergo VBD cord-015369-72cjogxz 6502 18 a a DT cord-015369-72cjogxz 6502 19 subtotal subtotal JJ cord-015369-72cjogxz 6502 20 resection resection NN cord-015369-72cjogxz 6502 21 of of IN cord-015369-72cjogxz 6502 22 the the DT cord-015369-72cjogxz 6502 23 sternum sternum NN cord-015369-72cjogxz 6502 24 . . . cord-015369-72cjogxz 6503 1 Reconstruction reconstruction NN cord-015369-72cjogxz 6503 2 was be VBD cord-015369-72cjogxz 6503 3 performed perform VBN cord-015369-72cjogxz 6503 4 with with IN cord-015369-72cjogxz 6503 5 an an DT cord-015369-72cjogxz 6503 6 additional additional JJ cord-015369-72cjogxz 6503 7 dualmesh dualmesh NN cord-015369-72cjogxz 6503 8 . . . cord-015369-72cjogxz 6504 1 The the DT cord-015369-72cjogxz 6504 2 fourth fourth JJ cord-015369-72cjogxz 6504 3 case case NN cord-015369-72cjogxz 6504 4 is be VBZ cord-015369-72cjogxz 6504 5 about about RB cord-015369-72cjogxz 6504 6 a a DT cord-015369-72cjogxz 6504 7 67-year 67-year JJ cord-015369-72cjogxz 6504 8 - - HYPH cord-015369-72cjogxz 6504 9 old old JJ cord-015369-72cjogxz 6504 10 woman woman NN cord-015369-72cjogxz 6504 11 with with IN cord-015369-72cjogxz 6504 12 a a DT cord-015369-72cjogxz 6504 13 giant giant JJ cord-015369-72cjogxz 6504 14 tumor tumor NN cord-015369-72cjogxz 6504 15 of of IN cord-015369-72cjogxz 6504 16 the the DT cord-015369-72cjogxz 6504 17 thoracic thoracic JJ cord-015369-72cjogxz 6504 18 wall wall NN cord-015369-72cjogxz 6504 19 ( ( -LRB- cord-015369-72cjogxz 6504 20 fibrosarcoma fibrosarcoma NNP cord-015369-72cjogxz 6504 21 ) ) -RRB- cord-015369-72cjogxz 6504 22 treated treat VBN cord-015369-72cjogxz 6504 23 with with IN cord-015369-72cjogxz 6504 24 radiacal radiacal JJ cord-015369-72cjogxz 6504 25 resection resection NN cord-015369-72cjogxz 6504 26 ( ( -LRB- cord-015369-72cjogxz 6504 27 5th 5th JJ cord-015369-72cjogxz 6504 28 to to IN cord-015369-72cjogxz 6504 29 8th 8th JJ cord-015369-72cjogxz 6504 30 rib rib NN cord-015369-72cjogxz 6504 31 ) ) -RRB- cord-015369-72cjogxz 6504 32 and and CC cord-015369-72cjogxz 6504 33 a a DT cord-015369-72cjogxz 6504 34 dualmesh dualmesh NN cord-015369-72cjogxz 6504 35 patch patch NN cord-015369-72cjogxz 6504 36 . . . cord-015369-72cjogxz 6505 1 The the DT cord-015369-72cjogxz 6505 2 use use NN cord-015369-72cjogxz 6505 3 of of IN cord-015369-72cjogxz 6505 4 the the DT cord-015369-72cjogxz 6505 5 Stratos Stratos NNP cord-015369-72cjogxz 6505 6 TM TM NNP cord-015369-72cjogxz 6505 7 System System NNP cord-015369-72cjogxz 6505 8 represents represent VBZ cord-015369-72cjogxz 6505 9 a a DT cord-015369-72cjogxz 6505 10 safe safe JJ cord-015369-72cjogxz 6505 11 and and CC cord-015369-72cjogxz 6505 12 practical practical JJ cord-015369-72cjogxz 6505 13 approach approach NN cord-015369-72cjogxz 6505 14 for for IN cord-015369-72cjogxz 6505 15 the the DT cord-015369-72cjogxz 6505 16 correction correction NN cord-015369-72cjogxz 6505 17 of of IN cord-015369-72cjogxz 6505 18 chest chest NN cord-015369-72cjogxz 6505 19 wall wall NN cord-015369-72cjogxz 6505 20 deformities deformity NNS cord-015369-72cjogxz 6505 21 and and CC cord-015369-72cjogxz 6505 22 the the DT cord-015369-72cjogxz 6505 23 reconstruction reconstruction NN cord-015369-72cjogxz 6505 24 of of IN cord-015369-72cjogxz 6505 25 the the DT cord-015369-72cjogxz 6505 26 chest chest NN cord-015369-72cjogxz 6505 27 wall wall NN cord-015369-72cjogxz 6505 28 after after IN cord-015369-72cjogxz 6505 29 tumor tumor NN cord-015369-72cjogxz 6505 30 removal removal NN cord-015369-72cjogxz 6505 31 . . . cord-015369-72cjogxz 6506 1 artery artery NN cord-015369-72cjogxz 6506 2 disease disease NN cord-015369-72cjogxz 6506 3 . . . cord-015369-72cjogxz 6507 1 The the DT cord-015369-72cjogxz 6507 2 underlying underlying JJ cord-015369-72cjogxz 6507 3 mechanism mechanism NN cord-015369-72cjogxz 6507 4 remains remain VBZ cord-015369-72cjogxz 6507 5 largely largely RB cord-015369-72cjogxz 6507 6 unknown unknown JJ cord-015369-72cjogxz 6507 7 . . . cord-015369-72cjogxz 6508 1 Methods method NNS cord-015369-72cjogxz 6508 2 . . . cord-015369-72cjogxz 6509 1 Endothelial endothelial JJ cord-015369-72cjogxz 6509 2 cells cell NNS cord-015369-72cjogxz 6509 3 and and CC cord-015369-72cjogxz 6509 4 fibroblasts fibroblast NNS cord-015369-72cjogxz 6509 5 were be VBD cord-015369-72cjogxz 6509 6 established establish VBN cord-015369-72cjogxz 6509 7 from from IN cord-015369-72cjogxz 6509 8 rat rat NN cord-015369-72cjogxz 6509 9 hearts heart NNS cord-015369-72cjogxz 6509 10 . . . cord-015369-72cjogxz 6510 1 Additionally additionally RB cord-015369-72cjogxz 6510 2 H9C2-cardiomyocytes H9C2-cardiomyocytes NNPS cord-015369-72cjogxz 6510 3 were be VBD cord-015369-72cjogxz 6510 4 used use VBN cord-015369-72cjogxz 6510 5 . . . cord-015369-72cjogxz 6511 1 A a DT cord-015369-72cjogxz 6511 2 water water NN cord-015369-72cjogxz 6511 3 bath bath NN cord-015369-72cjogxz 6511 4 was be VBD cord-015369-72cjogxz 6511 5 designed design VBN cord-015369-72cjogxz 6511 6 to to TO cord-015369-72cjogxz 6511 7 avoid avoid VB cord-015369-72cjogxz 6511 8 distracting distract VBG cord-015369-72cjogxz 6511 9 physical physical JJ cord-015369-72cjogxz 6511 10 effects effect NNS cord-015369-72cjogxz 6511 11 . . . cord-015369-72cjogxz 6512 1 Adherent adherent JJ cord-015369-72cjogxz 6512 2 cells cell NNS cord-015369-72cjogxz 6512 3 in in IN cord-015369-72cjogxz 6512 4 cell cell NN cord-015369-72cjogxz 6512 5 culture culture NN cord-015369-72cjogxz 6512 6 flasks flask NNS cord-015369-72cjogxz 6512 7 filled fill VBN cord-015369-72cjogxz 6512 8 with with IN cord-015369-72cjogxz 6512 9 culture culture NN cord-015369-72cjogxz 6512 10 medium medium NN cord-015369-72cjogxz 6512 11 were be VBD cord-015369-72cjogxz 6512 12 dunked dunk VBN cord-015369-72cjogxz 6512 13 into into IN cord-015369-72cjogxz 6512 14 the the DT cord-015369-72cjogxz 6512 15 bath bath NN cord-015369-72cjogxz 6512 16 . . . cord-015369-72cjogxz 6513 1 SW SW NNP cord-015369-72cjogxz 6513 2 ( ( -LRB- cord-015369-72cjogxz 6513 3 0.15 0.15 CD cord-015369-72cjogxz 6513 4 mJ mJ NNP cord-015369-72cjogxz 6513 5 / / SYM cord-015369-72cjogxz 6513 6 mm mm NNP cord-015369-72cjogxz 6513 7 2 2 CD cord-015369-72cjogxz 6513 8 ) ) -RRB- cord-015369-72cjogxz 6513 9 were be VBD cord-015369-72cjogxz 6513 10 applied apply VBN cord-015369-72cjogxz 6513 11 . . . cord-015369-72cjogxz 6514 1 Analysis analysis NN cord-015369-72cjogxz 6514 2 were be VBD cord-015369-72cjogxz 6514 3 performed perform VBN cord-015369-72cjogxz 6514 4 over over IN cord-015369-72cjogxz 6514 5 a a DT cord-015369-72cjogxz 6514 6 period period NN cord-015369-72cjogxz 6514 7 of of IN cord-015369-72cjogxz 6514 8 7 7 CD cord-015369-72cjogxz 6514 9 days day NNS cord-015369-72cjogxz 6514 10 . . . cord-015369-72cjogxz 6515 1 Results result NNS cord-015369-72cjogxz 6515 2 . . . cord-015369-72cjogxz 6516 1 SW SW NNP cord-015369-72cjogxz 6516 2 stimulate stimulate VBP cord-015369-72cjogxz 6516 3 every every DT cord-015369-72cjogxz 6516 4 cardiac cardiac JJ cord-015369-72cjogxz 6516 5 cell cell NN cord-015369-72cjogxz 6516 6 type type NN cord-015369-72cjogxz 6516 7 to to IN cord-015369-72cjogxz 6516 8 a a DT cord-015369-72cjogxz 6516 9 different different JJ cord-015369-72cjogxz 6516 10 extent extent NN cord-015369-72cjogxz 6516 11 . . . cord-015369-72cjogxz 6517 1 Each each DT cord-015369-72cjogxz 6517 2 cell cell NN cord-015369-72cjogxz 6517 3 type type NN cord-015369-72cjogxz 6517 4 reacts react VBZ cord-015369-72cjogxz 6517 5 at at IN cord-015369-72cjogxz 6517 6 another another DT cord-015369-72cjogxz 6517 7 timepoint timepoint NN cord-015369-72cjogxz 6517 8 . . . cord-015369-72cjogxz 6518 1 The the DT cord-015369-72cjogxz 6518 2 distance distance NN cord-015369-72cjogxz 6518 3 between between IN cord-015369-72cjogxz 6518 4 applicator applicator NN cord-015369-72cjogxz 6518 5 and and CC cord-015369-72cjogxz 6518 6 cells cell NNS cord-015369-72cjogxz 6518 7 , , , cord-015369-72cjogxz 6518 8 as as RB cord-015369-72cjogxz 6518 9 well well RB cord-015369-72cjogxz 6518 10 as as IN cord-015369-72cjogxz 6518 11 the the DT cord-015369-72cjogxz 6518 12 energy energy NN cord-015369-72cjogxz 6518 13 flux flux NN cord-015369-72cjogxz 6518 14 density density NN cord-015369-72cjogxz 6518 15 have have VBP cord-015369-72cjogxz 6518 16 an an DT cord-015369-72cjogxz 6518 17 influence influence NN cord-015369-72cjogxz 6518 18 on on IN cord-015369-72cjogxz 6518 19 the the DT cord-015369-72cjogxz 6518 20 cells cell NNS cord-015369-72cjogxz 6518 21 ' ' POS cord-015369-72cjogxz 6518 22 behaviour behaviour NN cord-015369-72cjogxz 6518 23 . . . cord-015369-72cjogxz 6519 1 Between between IN cord-015369-72cjogxz 6519 2 days day NNS cord-015369-72cjogxz 6519 3 4 4 CD cord-015369-72cjogxz 6519 4 and and CC cord-015369-72cjogxz 6519 5 5 5 CD cord-015369-72cjogxz 6519 6 the the DT cord-015369-72cjogxz 6519 7 duplication duplication NN cord-015369-72cjogxz 6519 8 time time NN cord-015369-72cjogxz 6519 9 of of IN cord-015369-72cjogxz 6519 10 treated treat VBN cord-015369-72cjogxz 6519 11 cells cell NNS cord-015369-72cjogxz 6519 12 was be VBD cord-015369-72cjogxz 6519 13 significantly significantly RB cord-015369-72cjogxz 6519 14 higher high JJR cord-015369-72cjogxz 6519 15 compared compare VBN cord-015369-72cjogxz 6519 16 to to IN cord-015369-72cjogxz 6519 17 controls control NNS cord-015369-72cjogxz 6519 18 . . . cord-015369-72cjogxz 6520 1 Significant significant JJ cord-015369-72cjogxz 6520 2 differences difference NNS cord-015369-72cjogxz 6520 3 in in IN cord-015369-72cjogxz 6520 4 the the DT cord-015369-72cjogxz 6520 5 gene gene NN cord-015369-72cjogxz 6520 6 expression expression NN cord-015369-72cjogxz 6520 7 of of IN cord-015369-72cjogxz 6520 8 MMPs mmp NNS cord-015369-72cjogxz 6520 9 , , , cord-015369-72cjogxz 6520 10 TIMPs TIMPs NNP cord-015369-72cjogxz 6520 11 and and CC cord-015369-72cjogxz 6520 12 collagen collagen NN cord-015369-72cjogxz 6520 13 were be VBD cord-015369-72cjogxz 6520 14 shown show VBN cord-015369-72cjogxz 6520 15 . . . cord-015369-72cjogxz 6521 1 Treated treat VBN cord-015369-72cjogxz 6521 2 cells cell NNS cord-015369-72cjogxz 6521 3 do do VBP cord-015369-72cjogxz 6521 4 alter alter VB cord-015369-72cjogxz 6521 5 their -PRON- PRP$ cord-015369-72cjogxz 6521 6 cytoskeleton cytoskeleton NN cord-015369-72cjogxz 6521 7 ( ( -LRB- cord-015369-72cjogxz 6521 8 Vimentin Vimentin NNP cord-015369-72cjogxz 6521 9 , , , cord-015369-72cjogxz 6521 10 Tubulin Tubulin NNP cord-015369-72cjogxz 6521 11 , , , cord-015369-72cjogxz 6521 12 beta beta NN cord-015369-72cjogxz 6521 13 - - HYPH cord-015369-72cjogxz 6521 14 Actin Actin NNP cord-015369-72cjogxz 6521 15 ) ) -RRB- cord-015369-72cjogxz 6521 16 , , , cord-015369-72cjogxz 6521 17 show show VBP cord-015369-72cjogxz 6521 18 significantly significantly RB cord-015369-72cjogxz 6521 19 more more JJR cord-015369-72cjogxz 6521 20 proliferation proliferation NN cord-015369-72cjogxz 6521 21 ( ( -LRB- cord-015369-72cjogxz 6521 22 Ki-67 Ki-67 NFP cord-015369-72cjogxz 6521 23 ) ) -RRB- cord-015369-72cjogxz 6521 24 and and CC cord-015369-72cjogxz 6521 25 changes change NNS cord-015369-72cjogxz 6521 26 in in IN cord-015369-72cjogxz 6521 27 the the DT cord-015369-72cjogxz 6521 28 expression expression NN cord-015369-72cjogxz 6521 29 of of IN cord-015369-72cjogxz 6521 30 adhesion adhesion NN cord-015369-72cjogxz 6521 31 molecules molecule NNS cord-015369-72cjogxz 6521 32 ( ( -LRB- cord-015369-72cjogxz 6521 33 CD31 CD31 NNP cord-015369-72cjogxz 6521 34 ) ) -RRB- cord-015369-72cjogxz 6521 35 as as RB cord-015369-72cjogxz 6521 36 well well RB cord-015369-72cjogxz 6521 37 as as IN cord-015369-72cjogxz 6521 38 connexins connexins NNP cord-015369-72cjogxz 6521 39 40 40 CD cord-015369-72cjogxz 6521 40 , , , cord-015369-72cjogxz 6521 41 43 43 CD cord-015369-72cjogxz 6521 42 , , , cord-015369-72cjogxz 6521 43 45 45 CD cord-015369-72cjogxz 6521 44 . . . cord-015369-72cjogxz 6522 1 No no DT cord-015369-72cjogxz 6522 2 apoptosis apoptosis NN cord-015369-72cjogxz 6522 3 was be VBD cord-015369-72cjogxz 6522 4 found find VBN cord-015369-72cjogxz 6522 5 in in IN cord-015369-72cjogxz 6522 6 the the DT cord-015369-72cjogxz 6522 7 treatment treatment NN cord-015369-72cjogxz 6522 8 group group NN cord-015369-72cjogxz 6522 9 . . . cord-015369-72cjogxz 6523 1 Conclusions conclusion NNS cord-015369-72cjogxz 6523 2 . . . cord-015369-72cjogxz 6524 1 SW SW NNP cord-015369-72cjogxz 6524 2 activate activate VBP cord-015369-72cjogxz 6524 3 proliferation proliferation NN cord-015369-72cjogxz 6524 4 of of IN cord-015369-72cjogxz 6524 5 cardiac cardiac JJ cord-015369-72cjogxz 6524 6 cells cell NNS cord-015369-72cjogxz 6524 7 . . . cord-015369-72cjogxz 6525 1 Moreover moreover RB cord-015369-72cjogxz 6525 2 cells cell NNS cord-015369-72cjogxz 6525 3 alter alter VBP cord-015369-72cjogxz 6525 4 the the DT cord-015369-72cjogxz 6525 5 assembly assembly NN cord-015369-72cjogxz 6525 6 of of IN cord-015369-72cjogxz 6525 7 microfilaments microfilament NNS cord-015369-72cjogxz 6525 8 , , , cord-015369-72cjogxz 6525 9 thus thus RB cord-015369-72cjogxz 6525 10 seem seem VBP cord-015369-72cjogxz 6525 11 to to TO cord-015369-72cjogxz 6525 12 ameliorate ameliorate VB cord-015369-72cjogxz 6525 13 cell cell NN cord-015369-72cjogxz 6525 14 migration migration NN cord-015369-72cjogxz 6525 15 . . . cord-015369-72cjogxz 6526 1 Changes change NNS cord-015369-72cjogxz 6526 2 of of IN cord-015369-72cjogxz 6526 3 the the DT cord-015369-72cjogxz 6526 4 MMP MMP NNP cord-015369-72cjogxz 6526 5 and and CC cord-015369-72cjogxz 6526 6 TIMP TIMP NNP cord-015369-72cjogxz 6526 7 levels level NNS cord-015369-72cjogxz 6526 8 and and CC cord-015369-72cjogxz 6526 9 the the DT cord-015369-72cjogxz 6526 10 expression expression NN cord-015369-72cjogxz 6526 11 of of IN cord-015369-72cjogxz 6526 12 adhesion adhesion NN cord-015369-72cjogxz 6526 13 molecules molecule NNS cord-015369-72cjogxz 6526 14 seem seem VBP cord-015369-72cjogxz 6526 15 to to TO cord-015369-72cjogxz 6526 16 be be VB cord-015369-72cjogxz 6526 17 strongly strongly RB cord-015369-72cjogxz 6526 18 involved involve VBN cord-015369-72cjogxz 6526 19 in in IN cord-015369-72cjogxz 6526 20 the the DT cord-015369-72cjogxz 6526 21 SW SW NNP cord-015369-72cjogxz 6526 22 tissue tissue NN cord-015369-72cjogxz 6526 23 regenerative regenerative JJ cord-015369-72cjogxz 6526 24 effect effect NN cord-015369-72cjogxz 6526 25 on on IN cord-015369-72cjogxz 6526 26 ischemic ischemic JJ cord-015369-72cjogxz 6526 27 myocardium myocardium NN cord-015369-72cjogxz 6526 28 . . . cord-015369-72cjogxz 6527 1 Idiopathic idiopathic JJ cord-015369-72cjogxz 6527 2 dilated dilated JJ cord-015369-72cjogxz 6527 3 cardiomyopathy cardiomyopathy NN cord-015369-72cjogxz 6527 4 ( ( -LRB- cord-015369-72cjogxz 6527 5 DCM DCM NNP cord-015369-72cjogxz 6527 6 ) ) -RRB- cord-015369-72cjogxz 6527 7 is be VBZ cord-015369-72cjogxz 6527 8 characterized characterize VBN cord-015369-72cjogxz 6527 9 by by IN cord-015369-72cjogxz 6527 10 ventricular ventricular JJ cord-015369-72cjogxz 6527 11 wall wall NN cord-015369-72cjogxz 6527 12 remodeling remodeling NN cord-015369-72cjogxz 6527 13 and and CC cord-015369-72cjogxz 6527 14 an an DT cord-015369-72cjogxz 6527 15 increased increase VBN cord-015369-72cjogxz 6527 16 incidence incidence NN cord-015369-72cjogxz 6527 17 of of IN cord-015369-72cjogxz 6527 18 apoptosis apoptosis NN cord-015369-72cjogxz 6527 19 . . . cord-015369-72cjogxz 6528 1 Apollon Apollon NNP cord-015369-72cjogxz 6528 2 is be VBZ cord-015369-72cjogxz 6528 3 a a DT cord-015369-72cjogxz 6528 4 member member NN cord-015369-72cjogxz 6528 5 of of IN cord-015369-72cjogxz 6528 6 the the DT cord-015369-72cjogxz 6528 7 inhibitor inhibitor NN cord-015369-72cjogxz 6528 8 of of IN cord-015369-72cjogxz 6528 9 apoptosis apoptosis NN cord-015369-72cjogxz 6528 10 protein protein NN cord-015369-72cjogxz 6528 11 ( ( -LRB- cord-015369-72cjogxz 6528 12 IAP IAP NNP cord-015369-72cjogxz 6528 13 ) ) -RRB- cord-015369-72cjogxz 6528 14 family family NN cord-015369-72cjogxz 6528 15 that that WDT cord-015369-72cjogxz 6528 16 promotes promote VBZ cord-015369-72cjogxz 6528 17 cell cell NN cord-015369-72cjogxz 6528 18 survival survival NN cord-015369-72cjogxz 6528 19 by by IN cord-015369-72cjogxz 6528 20 ubiquitination ubiquitination NN cord-015369-72cjogxz 6528 21 facilitating facilitate VBG cord-015369-72cjogxz 6528 22 the the DT cord-015369-72cjogxz 6528 23 degradation degradation NN cord-015369-72cjogxz 6528 24 of of IN cord-015369-72cjogxz 6528 25 pro pro JJ cord-015369-72cjogxz 6528 26 - - JJ cord-015369-72cjogxz 6528 27 apoptotic apoptotic JJ cord-015369-72cjogxz 6528 28 molecules molecule NNS cord-015369-72cjogxz 6528 29 . . . cord-015369-72cjogxz 6529 1 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6529 2 belongs belong VBZ cord-015369-72cjogxz 6529 3 to to IN cord-015369-72cjogxz 6529 4 the the DT cord-015369-72cjogxz 6529 5 TNF TNF NNP cord-015369-72cjogxz 6529 6 - - HYPH cord-015369-72cjogxz 6529 7 receptor receptor NN cord-015369-72cjogxz 6529 8 - - HYPH cord-015369-72cjogxz 6529 9 associated associate VBN cord-015369-72cjogxz 6529 10 family family NN cord-015369-72cjogxz 6529 11 ubiquitinated ubiquitinate VBN cord-015369-72cjogxz 6529 12 by by IN cord-015369-72cjogxz 6529 13 other other JJ cord-015369-72cjogxz 6529 14 IAPs iaps NN cord-015369-72cjogxz 6529 15 after after IN cord-015369-72cjogxz 6529 16 pro pro JJ cord-015369-72cjogxz 6529 17 - - JJ cord-015369-72cjogxz 6529 18 apoptotic apoptotic JJ cord-015369-72cjogxz 6529 19 stimuli stimulus NNS cord-015369-72cjogxz 6529 20 . . . cord-015369-72cjogxz 6530 1 Whether whether IN cord-015369-72cjogxz 6530 2 the the DT cord-015369-72cjogxz 6530 3 Apollon/ apollon/ VBP cord-015369-72cjogxz 6530 4 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6530 5 system system NN cord-015369-72cjogxz 6530 6 may may MD cord-015369-72cjogxz 6530 7 mediate mediate VB cord-015369-72cjogxz 6530 8 programmed programmed JJ cord-015369-72cjogxz 6530 9 cell cell NN cord-015369-72cjogxz 6530 10 death death NN cord-015369-72cjogxz 6530 11 in in IN cord-015369-72cjogxz 6530 12 DCM DCM NNP cord-015369-72cjogxz 6530 13 is be VBZ cord-015369-72cjogxz 6530 14 unknown unknown JJ cord-015369-72cjogxz 6530 15 . . . cord-015369-72cjogxz 6531 1 Apollon Apollon NNP cord-015369-72cjogxz 6531 2 and and CC cord-015369-72cjogxz 6531 3 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6531 4 protein protein NN cord-015369-72cjogxz 6531 5 expression expression NN cord-015369-72cjogxz 6531 6 was be VBD cord-015369-72cjogxz 6531 7 examined examine VBN cord-015369-72cjogxz 6531 8 in in IN cord-015369-72cjogxz 6531 9 left left JJ cord-015369-72cjogxz 6531 10 ventricular ventricular JJ cord-015369-72cjogxz 6531 11 biopsies biopsy NNS cord-015369-72cjogxz 6531 12 of of IN cord-015369-72cjogxz 6531 13 explanted explanted JJ cord-015369-72cjogxz 6531 14 failing fail VBG cord-015369-72cjogxz 6531 15 hearts heart NNS cord-015369-72cjogxz 6531 16 using use VBG cord-015369-72cjogxz 6531 17 Western western JJ cord-015369-72cjogxz 6531 18 blotting blotting NN cord-015369-72cjogxz 6531 19 in in IN cord-015369-72cjogxz 6531 20 36 36 CD cord-015369-72cjogxz 6531 21 DCM DCM NNP cord-015369-72cjogxz 6531 22 patients patient NNS cord-015369-72cjogxz 6531 23 and and CC cord-015369-72cjogxz 6531 24 10 10 CD cord-015369-72cjogxz 6531 25 controls control NNS cord-015369-72cjogxz 6531 26 . . . cord-015369-72cjogxz 6532 1 Human human JJ cord-015369-72cjogxz 6532 2 cardiac cardiac NN cord-015369-72cjogxz 6532 3 cells cell NNS cord-015369-72cjogxz 6532 4 were be VBD cord-015369-72cjogxz 6532 5 transfected transfecte VBN cord-015369-72cjogxz 6532 6 with with IN cord-015369-72cjogxz 6532 7 a a DT cord-015369-72cjogxz 6532 8 plasmid plasmid NN cord-015369-72cjogxz 6532 9 containing contain VBG cord-015369-72cjogxz 6532 10 the the DT cord-015369-72cjogxz 6532 11 human human JJ cord-015369-72cjogxz 6532 12 Apollon Apollon NNP cord-015369-72cjogxz 6532 13 cDNA cdna NN cord-015369-72cjogxz 6532 14 or or CC cord-015369-72cjogxz 6532 15 control control NN cord-015369-72cjogxz 6532 16 vector vector NN cord-015369-72cjogxz 6532 17 and and CC cord-015369-72cjogxz 6532 18 were be VBD cord-015369-72cjogxz 6532 19 subsequently subsequently RB cord-015369-72cjogxz 6532 20 stressed stress VBN cord-015369-72cjogxz 6532 21 by by IN cord-015369-72cjogxz 6532 22 hypoxia hypoxia NN cord-015369-72cjogxz 6532 23 . . . cord-015369-72cjogxz 6533 1 Apollon Apollon NNP cord-015369-72cjogxz 6533 2 and and CC cord-015369-72cjogxz 6533 3 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6533 4 mRNA mRNA NNP cord-015369-72cjogxz 6533 5 expression expression NN cord-015369-72cjogxz 6533 6 was be VBD cord-015369-72cjogxz 6533 7 then then RB cord-015369-72cjogxz 6533 8 measured measure VBN cord-015369-72cjogxz 6533 9 in in IN cord-015369-72cjogxz 6533 10 cell cell NN cord-015369-72cjogxz 6533 11 lysates lysate NNS cord-015369-72cjogxz 6533 12 by by IN cord-015369-72cjogxz 6533 13 real real JJ cord-015369-72cjogxz 6533 14 time time NN cord-015369-72cjogxz 6533 15 RT RT NNP cord-015369-72cjogxz 6533 16 - - HYPH cord-015369-72cjogxz 6533 17 PCR PCR NNP cord-015369-72cjogxz 6533 18 and and CC cord-015369-72cjogxz 6533 19 TUNEL TUNEL NNP cord-015369-72cjogxz 6533 20 assays assay NNS cord-015369-72cjogxz 6533 21 were be VBD cord-015369-72cjogxz 6533 22 used use VBN cord-015369-72cjogxz 6533 23 to to TO cord-015369-72cjogxz 6533 24 determine determine VB cord-015369-72cjogxz 6533 25 the the DT cord-015369-72cjogxz 6533 26 apoptotic apoptotic JJ cord-015369-72cjogxz 6533 27 index index NN cord-015369-72cjogxz 6533 28 . . . cord-015369-72cjogxz 6534 1 In in IN cord-015369-72cjogxz 6534 2 DCM DCM NNP cord-015369-72cjogxz 6534 3 myocardial myocardial JJ cord-015369-72cjogxz 6534 4 tissue tissue NN cord-015369-72cjogxz 6534 5 , , , cord-015369-72cjogxz 6534 6 Apollon Apollon NNP cord-015369-72cjogxz 6534 7 expression expression NN cord-015369-72cjogxz 6534 8 was be VBD cord-015369-72cjogxz 6534 9 downregulated downregulate VBN cord-015369-72cjogxz 6534 10 and and CC cord-015369-72cjogxz 6534 11 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6534 12 was be VBD cord-015369-72cjogxz 6534 13 upregulated upregulate VBN cord-015369-72cjogxz 6534 14 compared compare VBN cord-015369-72cjogxz 6534 15 to to TO cord-015369-72cjogxz 6534 16 control control VB cord-015369-72cjogxz 6534 17 hearts heart NNS cord-015369-72cjogxz 6534 18 ( ( -LRB- cord-015369-72cjogxz 6534 19 p p NN cord-015369-72cjogxz 6534 20 < < XX cord-015369-72cjogxz 6534 21 0.01 0.01 CD cord-015369-72cjogxz 6534 22 ) ) -RRB- cord-015369-72cjogxz 6534 23 . . . cord-015369-72cjogxz 6535 1 Cell cell NN cord-015369-72cjogxz 6535 2 stress stress NN cord-015369-72cjogxz 6535 3 resulted result VBD cord-015369-72cjogxz 6535 4 in in IN cord-015369-72cjogxz 6535 5 increased increase VBN cord-015369-72cjogxz 6535 6 apoptosis apoptosis NN cord-015369-72cjogxz 6535 7 in in IN cord-015369-72cjogxz 6535 8 cardiac cardiac JJ cord-015369-72cjogxz 6535 9 cells cell NNS cord-015369-72cjogxz 6535 10 in in IN cord-015369-72cjogxz 6535 11 vitro vitro FW cord-015369-72cjogxz 6535 12 with with IN cord-015369-72cjogxz 6535 13 downregulation downregulation NN cord-015369-72cjogxz 6535 14 of of IN cord-015369-72cjogxz 6535 15 Apollon Apollon NNP cord-015369-72cjogxz 6535 16 and and CC cord-015369-72cjogxz 6535 17 upregulation upregulation NN cord-015369-72cjogxz 6535 18 of of IN cord-015369-72cjogxz 6535 19 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6535 20 mRNA mrna NN cord-015369-72cjogxz 6535 21 expression expression NN cord-015369-72cjogxz 6535 22 compared compare VBN cord-015369-72cjogxz 6535 23 to to IN cord-015369-72cjogxz 6535 24 control control NN cord-015369-72cjogxz 6535 25 cells cell NNS cord-015369-72cjogxz 6535 26 ( ( -LRB- cord-015369-72cjogxz 6535 27 p p NN cord-015369-72cjogxz 6535 28 < < XX cord-015369-72cjogxz 6535 29 0.001 0.001 CD cord-015369-72cjogxz 6535 30 ) ) -RRB- cord-015369-72cjogxz 6535 31 . . . cord-015369-72cjogxz 6536 1 Transfection transfection NN cord-015369-72cjogxz 6536 2 with with IN cord-015369-72cjogxz 6536 3 Apollon Apollon NNP cord-015369-72cjogxz 6536 4 increased increase VBD cord-015369-72cjogxz 6536 5 Apollon Apollon NNP cord-015369-72cjogxz 6536 6 and and CC cord-015369-72cjogxz 6536 7 decreased decrease VBD cord-015369-72cjogxz 6536 8 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6536 9 mRNA mrna NN cord-015369-72cjogxz 6536 10 expression expression NN cord-015369-72cjogxz 6536 11 in in IN cord-015369-72cjogxz 6536 12 cell cell NN cord-015369-72cjogxz 6536 13 lysates lysate NNS cord-015369-72cjogxz 6536 14 ( ( -LRB- cord-015369-72cjogxz 6536 15 p p NN cord-015369-72cjogxz 6536 16 < < XX cord-015369-72cjogxz 6536 17 0.001 0.001 CD cord-015369-72cjogxz 6536 18 ) ) -RRB- cord-015369-72cjogxz 6536 19 and and CC cord-015369-72cjogxz 6536 20 completely completely RB cord-015369-72cjogxz 6536 21 abolished abolish VBN cord-015369-72cjogxz 6536 22 hypoxia hypoxia NN cord-015369-72cjogxz 6536 23 - - HYPH cord-015369-72cjogxz 6536 24 induced induce VBN cord-015369-72cjogxz 6536 25 apoptosis apoptosis NN cord-015369-72cjogxz 6536 26 . . . cord-015369-72cjogxz 6537 1 These these DT cord-015369-72cjogxz 6537 2 results result NNS cord-015369-72cjogxz 6537 3 suggest suggest VBP cord-015369-72cjogxz 6537 4 for for IN cord-015369-72cjogxz 6537 5 the the DT cord-015369-72cjogxz 6537 6 first first JJ cord-015369-72cjogxz 6537 7 time time NN cord-015369-72cjogxz 6537 8 that that WDT cord-015369-72cjogxz 6537 9 Apollon Apollon NNP cord-015369-72cjogxz 6537 10 regulates regulate VBZ cord-015369-72cjogxz 6537 11 the the DT cord-015369-72cjogxz 6537 12 level level NN cord-015369-72cjogxz 6537 13 of of IN cord-015369-72cjogxz 6537 14 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6537 15 and and CC cord-015369-72cjogxz 6537 16 that that IN cord-015369-72cjogxz 6537 17 both both CC cord-015369-72cjogxz 6537 18 Apollon Apollon NNP cord-015369-72cjogxz 6537 19 and and CC cord-015369-72cjogxz 6537 20 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6537 21 are be VBP cord-015369-72cjogxz 6537 22 involved involve VBN cord-015369-72cjogxz 6537 23 in in IN cord-015369-72cjogxz 6537 24 the the DT cord-015369-72cjogxz 6537 25 programmed programmed JJ cord-015369-72cjogxz 6537 26 cell cell NN cord-015369-72cjogxz 6537 27 death death NN cord-015369-72cjogxz 6537 28 associated associate VBN cord-015369-72cjogxz 6537 29 with with IN cord-015369-72cjogxz 6537 30 DCM DCM NNP cord-015369-72cjogxz 6537 31 . . . cord-015369-72cjogxz 6538 1 Upregulation Upregulation NNP cord-015369-72cjogxz 6538 2 of of IN cord-015369-72cjogxz 6538 3 Apollon Apollon NNP cord-015369-72cjogxz 6538 4 with with IN cord-015369-72cjogxz 6538 5 subsequent subsequent JJ cord-015369-72cjogxz 6538 6 TRAF2 TRAF2 NNP cord-015369-72cjogxz 6538 7 suppression suppression NN cord-015369-72cjogxz 6538 8 might may MD cord-015369-72cjogxz 6538 9 therefore therefore RB cord-015369-72cjogxz 6538 10 constitute constitute VB cord-015369-72cjogxz 6538 11 a a DT cord-015369-72cjogxz 6538 12 novel novel JJ cord-015369-72cjogxz 6538 13 strategy strategy NN cord-015369-72cjogxz 6538 14 in in IN cord-015369-72cjogxz 6538 15 DCM DCM NNP cord-015369-72cjogxz 6538 16 treatment treatment NN cord-015369-72cjogxz 6538 17 . . . cord-015369-72cjogxz 6539 1 monalvenen monalvenen NNP cord-015369-72cjogxz 6539 2 durchgeführt durchgeführt NNP cord-015369-72cjogxz 6539 3 . . . cord-015369-72cjogxz 6540 1 Zur Zur NNP cord-015369-72cjogxz 6540 2 Kontrolle Kontrolle NNP cord-015369-72cjogxz 6540 3 des des NNP cord-015369-72cjogxz 6540 4 Operationserfolges Operationserfolges NNP cord-015369-72cjogxz 6540 5 wurde wurde NN cord-015369-72cjogxz 6540 6 zusätzlich zusätzlich NNP cord-015369-72cjogxz 6540 7 ein ein NNP cord-015369-72cjogxz 6540 8 permanenter permanenter NNP cord-015369-72cjogxz 6540 9 Loop Loop NNP cord-015369-72cjogxz 6540 10 - - HYPH cord-015369-72cjogxz 6540 11 Recorder recorder NN cord-015369-72cjogxz 6540 12 Medtronic Medtronic NNP cord-015369-72cjogxz 6540 13 Reveal reveal VBP cord-015369-72cjogxz 6540 14 TM TM NNP cord-015369-72cjogxz 6540 15 XT XT NNP cord-015369-72cjogxz 6540 16 implantiert implantiert NN cord-015369-72cjogxz 6540 17 . . . cord-015369-72cjogxz 6541 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6541 2 . . . cord-015369-72cjogxz 6542 1 Es Es NNP cord-015369-72cjogxz 6542 2 konnten konnten NNP cord-015369-72cjogxz 6542 3 4 4 CD cord-015369-72cjogxz 6542 4 Ganglien Ganglien NNP cord-015369-72cjogxz 6542 5 isoliert isoliert NN cord-015369-72cjogxz 6543 1 und und NNP cord-015369-72cjogxz 6544 1 selektiv selektiv NNP cord-015369-72cjogxz 6544 2 abliert abliert NNP cord-015369-72cjogxz 6544 3 werden werden NNP cord-015369-72cjogxz 6544 4 . . . cord-015369-72cjogxz 6545 1 Postoperativ postoperativ JJ cord-015369-72cjogxz 6545 2 trat trat NN cord-015369-72cjogxz 6545 3 normofrequenter normofrequenter NN cord-015369-72cjogxz 6545 4 Sinusrhythmus Sinusrhythmus NNP cord-015369-72cjogxz 6545 5 ein ein NNP cord-015369-72cjogxz 6545 6 , , , cord-015369-72cjogxz 6546 1 ein ein NNP cord-015369-72cjogxz 6546 2 postoperatives postoperatives NNP cord-015369-72cjogxz 6546 3 24-stunden 24-stunden CD cord-015369-72cjogxz 6547 1 Holter Holter NNP cord-015369-72cjogxz 6547 2 zeigte zeigte NN cord-015369-72cjogxz 6547 3 durchgehenden durchgehenden NN cord-015369-72cjogxz 6547 4 Sinusrhythmus Sinusrhythmus NNP cord-015369-72cjogxz 6547 5 mit mit NNP cord-015369-72cjogxz 6547 6 einer einer NNP cord-015369-72cjogxz 6548 1 Frequenz Frequenz NNP cord-015369-72cjogxz 6548 2 von von NNP cord-015369-72cjogxz 6548 3 54 54 CD cord-015369-72cjogxz 6548 4 - - SYM cord-015369-72cjogxz 6548 5 84 84 CD cord-015369-72cjogxz 6548 6 / / SYM cord-015369-72cjogxz 6548 7 min min NN cord-015369-72cjogxz 6548 8 . . . cord-015369-72cjogxz 6549 1 Bei Bei NNP cord-015369-72cjogxz 6549 2 den den NNP cord-015369-72cjogxz 6549 3 Kontrollen Kontrollen NNP cord-015369-72cjogxz 6549 4 nach nach NNP cord-015369-72cjogxz 6549 5 3 3 CD cord-015369-72cjogxz 6550 1 und und NNP cord-015369-72cjogxz 6551 1 6 6 CD cord-015369-72cjogxz 6551 2 Monaten Monaten NNP cord-015369-72cjogxz 6551 3 ergab ergab NNP cord-015369-72cjogxz 6551 4 die die NN cord-015369-72cjogxz 6552 1 Abfrage Abfrage NNP cord-015369-72cjogxz 6552 2 des des FW cord-015369-72cjogxz 6552 3 Loop Loop NNP cord-015369-72cjogxz 6552 4 Recorders Recorders NNPS cord-015369-72cjogxz 6552 5 einen einen VBP cord-015369-72cjogxz 6552 6 stabilen stabilen NNP cord-015369-72cjogxz 6552 7 permanenten permanenten NNP cord-015369-72cjogxz 6552 8 Sinusrhythmus Sinusrhythmus NNP cord-015369-72cjogxz 6552 9 ohne ohne NNP cord-015369-72cjogxz 6552 10 aufgezeichnete aufgezeichnete NN cord-015369-72cjogxz 6552 11 Vorhofflimmerepisoden Vorhofflimmerepisoden NNP cord-015369-72cjogxz 6552 12 . . . cord-015369-72cjogxz 6553 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6553 2 . . . cord-015369-72cjogxz 6554 1 Die die VB cord-015369-72cjogxz 6554 2 Selektive Selektive NNP cord-015369-72cjogxz 6554 3 Isolation isolation NN cord-015369-72cjogxz 6554 4 und und IN cord-015369-72cjogxz 6554 5 Ablation ablation NN cord-015369-72cjogxz 6554 6 der der NNP cord-015369-72cjogxz 6554 7 autonomen autonomen NNP cord-015369-72cjogxz 6555 1 Ganglien Ganglien NNP cord-015369-72cjogxz 6556 1 i -PRON- PRP cord-015369-72cjogxz 6556 2 m be VBP cord-015369-72cjogxz 6556 3 Rahmen Rahmen NNP cord-015369-72cjogxz 6556 4 der der NNP cord-015369-72cjogxz 6556 5 Vorhofablation Vorhofablation NNP cord-015369-72cjogxz 6556 6 bei bei NNP cord-015369-72cjogxz 6556 7 Vorhofflimmern Vorhofflimmern NNP cord-015369-72cjogxz 6557 1 kann kann NNP cord-015369-72cjogxz 6557 2 zu zu NNP cord-015369-72cjogxz 6557 3 einer einer NNP cord-015369-72cjogxz 6557 4 Verbesserung Verbesserung NNP cord-015369-72cjogxz 6557 5 der der NNP cord-015369-72cjogxz 6557 6 Operationserfolges Operationserfolges NNP cord-015369-72cjogxz 6557 7 führen führen NNP cord-015369-72cjogxz 6557 8 , , , cord-015369-72cjogxz 6557 9 wobei wobei JJ cord-015369-72cjogxz 6557 10 bei bei NNP cord-015369-72cjogxz 6557 11 unserem unserem NNP cord-015369-72cjogxz 6558 1 Patienten Patienten NNP cord-015369-72cjogxz 6558 2 die die VBP cord-015369-72cjogxz 6558 3 normale normale NN cord-015369-72cjogxz 6559 1 Sinusknotenfunktion Sinusknotenfunktion NNP cord-015369-72cjogxz 6559 2 erhalten erhalten NNP cord-015369-72cjogxz 6559 3 blieb blieb NNP cord-015369-72cjogxz 6559 4 . . . cord-015369-72cjogxz 6560 1 Perioperative Perioperative NNP cord-015369-72cjogxz 6560 2 Antibiotikaprohyplaxe Antibiotikaprohyplaxe NNP cord-015369-72cjogxz 6560 3 bei bei NNP cord-015369-72cjogxz 6560 4 herzchirurgischen herzchirurgischen NNP cord-015369-72cjogxz 6560 5 Eingriffendas Eingriffendas NNP cord-015369-72cjogxz 6560 6 erfolgreiche erfolgreiche NNP cord-015369-72cjogxz 6560 7 Regime Regime NNP cord-015369-72cjogxz 6560 8 der der NNP cord-015369-72cjogxz 6560 9 Grazer Grazer NNP cord-015369-72cjogxz 6560 10 Herzchirurgie Herzchirurgie NNP cord-015369-72cjogxz 6560 11 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6560 12 . . . cord-015369-72cjogxz 6561 1 Weichteilinfektionen Weichteilinfektionen NNP cord-015369-72cjogxz 6561 2 sind sind NNPS cord-015369-72cjogxz 6561 3 in in IN cord-015369-72cjogxz 6561 4 der der NNP cord-015369-72cjogxz 6561 5 Herzchirurgie Herzchirurgie NNP cord-015369-72cjogxz 6561 6 eine eine JJ cord-015369-72cjogxz 6561 7 bekannte bekannte JJ cord-015369-72cjogxz 6561 8 Komplikation Komplikation NNP cord-015369-72cjogxz 6561 9 . . . cord-015369-72cjogxz 6562 1 In in IN cord-015369-72cjogxz 6562 2 der der NN cord-015369-72cjogxz 6562 3 Literatur Literatur NNP cord-015369-72cjogxz 6562 4 kommt kommt NNP cord-015369-72cjogxz 6562 5 es es NNP cord-015369-72cjogxz 6562 6 in in IN cord-015369-72cjogxz 6562 7 7 7 CD cord-015369-72cjogxz 6562 8 % % NN cord-015369-72cjogxz 6563 1 zu zu NNP cord-015369-72cjogxz 6563 2 oberflächlichen oberflächlichen NNP cord-015369-72cjogxz 6563 3 Infektionen Infektionen NNP cord-015369-72cjogxz 6563 4 , , , cord-015369-72cjogxz 6563 5 in in IN cord-015369-72cjogxz 6563 6 1,6 1,6 CD cord-015369-72cjogxz 6563 7 % % NN cord-015369-72cjogxz 6563 8 zu zu NN cord-015369-72cjogxz 6563 9 tiefen tiefen NNP cord-015369-72cjogxz 6563 10 Steruminfekten Steruminfekten NNP cord-015369-72cjogxz 6563 11 , , , cord-015369-72cjogxz 6563 12 in in IN cord-015369-72cjogxz 6563 13 1 1 CD cord-015369-72cjogxz 6563 14 - - SYM cord-015369-72cjogxz 6563 15 2 2 CD cord-015369-72cjogxz 6563 16 % % NN cord-015369-72cjogxz 6563 17 der der NNP cord-015369-72cjogxz 6563 18 Fälle Fälle NNP cord-015369-72cjogxz 6563 19 wird wird NNP cord-015369-72cjogxz 6563 20 von von NNP cord-015369-72cjogxz 6563 21 postoperativer postoperativer NNP cord-015369-72cjogxz 6563 22 Mediastinitis Mediastinitis NNP cord-015369-72cjogxz 6563 23 mit mit NNP cord-015369-72cjogxz 6563 24 einer einer NNP cord-015369-72cjogxz 6563 25 Sternumdehiszenz Sternumdehiszenz NNP cord-015369-72cjogxz 6563 26 berichtet berichtet NNP cord-015369-72cjogxz 6563 27 . . . cord-015369-72cjogxz 6564 1 Die die VB cord-015369-72cjogxz 6564 2 Mortalität Mortalität NNP cord-015369-72cjogxz 6564 3 bei bei NNP cord-015369-72cjogxz 6564 4 den den NNP cord-015369-72cjogxz 6564 5 mediastinalen mediastinalen NNP cord-015369-72cjogxz 6564 6 Infektionen Infektionen NNP cord-015369-72cjogxz 6564 7 ist ist NNP cord-015369-72cjogxz 6564 8 mit mit NNP cord-015369-72cjogxz 6565 1 9 9 LS cord-015369-72cjogxz 6565 2 - - SYM cord-015369-72cjogxz 6565 3 14 14 CD cord-015369-72cjogxz 6565 4 % % NN cord-015369-72cjogxz 6565 5 hoch hoch NNP cord-015369-72cjogxz 6566 1 , , , cord-015369-72cjogxz 6566 2 die die VB cord-015369-72cjogxz 6566 3 Kosten Kosten NNP cord-015369-72cjogxz 6566 4 für für NNP cord-015369-72cjogxz 6566 5 Patienten Patienten NNP cord-015369-72cjogxz 6566 6 mit mit NNP cord-015369-72cjogxz 6566 7 sternalen sternalen NNP cord-015369-72cjogxz 6567 1 Wundinfekten Wundinfekten NNP cord-015369-72cjogxz 6568 1 sind sind NNP cord-015369-72cjogxz 6569 1 2,8 2,8 CD cord-015369-72cjogxz 6569 2 Mal Mal NNP cord-015369-72cjogxz 6570 1 so so RB cord-015369-72cjogxz 6570 2 hoch hoch NNP cord-015369-72cjogxz 6571 1 wie wie NNP cord-015369-72cjogxz 6571 2 für für NNP cord-015369-72cjogxz 6572 1 Patienten Patienten NNP cord-015369-72cjogxz 6572 2 mit mit VBD cord-015369-72cjogxz 6572 3 unkompliziertem unkompliziertem NNP cord-015369-72cjogxz 6572 4 postoperativem postoperativem NNP cord-015369-72cjogxz 6572 5 Verlauf Verlauf NNP cord-015369-72cjogxz 6572 6 . . . cord-015369-72cjogxz 6573 1 Methodik Methodik NNP cord-015369-72cjogxz 6573 2 . . . cord-015369-72cjogxz 6574 1 An an DT cord-015369-72cjogxz 6574 2 der der NN cord-015369-72cjogxz 6574 3 Herzchirurgie Herzchirurgie NNP cord-015369-72cjogxz 6574 4 Graz Graz NNP cord-015369-72cjogxz 6574 5 wird wird NNP cord-015369-72cjogxz 6574 6 seit seit NNP cord-015369-72cjogxz 6574 7 1996 1996 CD cord-015369-72cjogxz 6575 1 folgendes folgendes NNP cord-015369-72cjogxz 6575 2 antibiotisches antibiotisches NNP cord-015369-72cjogxz 6575 3 Regime Regime NNP cord-015369-72cjogxz 6575 4 angewendet angewendet NNP cord-015369-72cjogxz 6575 5 : : : cord-015369-72cjogxz 6576 1 eine eine NNP cord-015369-72cjogxz 6576 2 Stunde stunde JJ cord-015369-72cjogxz 6576 3 präoperativ präoperativ NN cord-015369-72cjogxz 6576 4 wird wird NNP cord-015369-72cjogxz 6576 5 Cefuroxim Cefuroxim NNP cord-015369-72cjogxz 6576 6 iv iv NNP cord-015369-72cjogxz 6576 7 gegeben gegeben NNP cord-015369-72cjogxz 6576 8 , , , cord-015369-72cjogxz 6576 9 unmittelbar unmittelbar NN cord-015369-72cjogxz 6576 10 vor vor NNP cord-015369-72cjogxz 6576 11 Hautschnitt Hautschnitt NNP cord-015369-72cjogxz 6576 12 Teicoplanin Teicoplanin NNPS cord-015369-72cjogxz 6576 13 , , , cord-015369-72cjogxz 6576 14 die die VB cord-015369-72cjogxz 6576 15 zweite zweite NNP cord-015369-72cjogxz 6576 16 Dosisgabe Dosisgabe NNP cord-015369-72cjogxz 6576 17 der der NN cord-015369-72cjogxz 6576 18 beiden beiden NNP cord-015369-72cjogxz 6576 19 Antibiotika Antibiotika NNP cord-015369-72cjogxz 6576 20 erfolgt erfolgt NNP cord-015369-72cjogxz 6576 21 noch noch NNP cord-015369-72cjogxz 6576 22 an an DT cord-015369-72cjogxz 6576 23 der der NN cord-015369-72cjogxz 6576 24 HLM HLM NNP cord-015369-72cjogxz 6576 25 . . . cord-015369-72cjogxz 6577 1 Das Das NNP cord-015369-72cjogxz 6577 2 Cephalosporin Cephalosporin NNP cord-015369-72cjogxz 6577 3 wird wird NNP cord-015369-72cjogxz 6577 4 für für NNP cord-015369-72cjogxz 6577 5 24 24 CD cord-015369-72cjogxz 6577 6 h h NNP cord-015369-72cjogxz 6577 7 postoperativ postoperativ NN cord-015369-72cjogxz 6577 8 bei bei NNP cord-015369-72cjogxz 6577 9 CABG CABG NNP cord-015369-72cjogxz 6577 10 verabreicht verabreicht NNP cord-015369-72cjogxz 6577 11 , , , cord-015369-72cjogxz 6577 12 bei bei NNP cord-015369-72cjogxz 6577 13 Klappenoperationen Klappenoperationen NNP cord-015369-72cjogxz 6578 1 bis bis NNP cord-015369-72cjogxz 6578 2 zum zum NNP cord-015369-72cjogxz 6578 3 3 3 CD cord-015369-72cjogxz 6578 4 . . . cord-015369-72cjogxz 6579 1 postoperativen postoperativen NNP cord-015369-72cjogxz 6580 1 Tag tag NN cord-015369-72cjogxz 6580 2 . . . cord-015369-72cjogxz 6581 1 Die die VB cord-015369-72cjogxz 6581 2 Daten Daten NNP cord-015369-72cjogxz 6581 3 beziehen beziehen NNP cord-015369-72cjogxz 6581 4 sich sich NNP cord-015369-72cjogxz 6581 5 bis bis NNP cord-015369-72cjogxz 6581 6 zur zur NNP cord-015369-72cjogxz 6581 7 Entlassung Entlassung NNP cord-015369-72cjogxz 6581 8 ins ins NNPS cord-015369-72cjogxz 6581 9 Rehabilitationszentrum Rehabilitationszentrum NNP cord-015369-72cjogxz 6581 10 . . . cord-015369-72cjogxz 6582 1 Bei Bei NNP cord-015369-72cjogxz 6582 2 Langliegern Langliegern NNP cord-015369-72cjogxz 6582 3 werden werden NNP cord-015369-72cjogxz 6582 4 Antibiotika Antibiotika NNP cord-015369-72cjogxz 6582 5 nur nur NNP cord-015369-72cjogxz 6582 6 nach nach NN cord-015369-72cjogxz 6582 7 vorliegendem vorliegendem NNP cord-015369-72cjogxz 6582 8 Antibiogramm Antibiogramm NNP cord-015369-72cjogxz 6582 9 verabreicht verabreicht NN cord-015369-72cjogxz 6582 10 . . . cord-015369-72cjogxz 6583 1 Alle Alle NNP cord-015369-72cjogxz 6584 1 Patienten Patienten NNP cord-015369-72cjogxz 6584 2 werden werden NNP cord-015369-72cjogxz 6585 1 präoperativ präoperativ NNP cord-015369-72cjogxz 6585 2 auf auf NNP cord-015369-72cjogxz 6585 3 MRSA MRSA NNP cord-015369-72cjogxz 6585 4 mittels mittels NNPS cord-015369-72cjogxz 6585 5 Nasenabstrich Nasenabstrich NNP cord-015369-72cjogxz 6585 6 ( ( -LRB- cord-015369-72cjogxz 6585 7 positiv positiv JJ cord-015369-72cjogxz 6585 8 bei bei NNP cord-015369-72cjogxz 6585 9 n n NNP cord-015369-72cjogxz 6585 10 ¼ ¼ NNP cord-015369-72cjogxz 6585 11 27 27 CD cord-015369-72cjogxz 6585 12 ) ) -RRB- cord-015369-72cjogxz 6585 13 gescreent gescreent NN cord-015369-72cjogxz 6585 14 . . . cord-015369-72cjogxz 6586 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6586 2 . . . cord-015369-72cjogxz 6587 1 2008 2008 CD cord-015369-72cjogxz 6588 1 kam kam NNP cord-015369-72cjogxz 6588 2 es es NNP cord-015369-72cjogxz 6588 3 weder weder NNP cord-015369-72cjogxz 6588 4 zu zu NNP cord-015369-72cjogxz 6589 1 postoperativer postoperativer NNP cord-015369-72cjogxz 6589 2 Mediastinitis Mediastinitis NNP cord-015369-72cjogxz 6589 3 noch noch NNP cord-015369-72cjogxz 6589 4 zu zu NNP cord-015369-72cjogxz 6590 1 chirurgisch chirurgisch NNP cord-015369-72cjogxz 6590 2 behandlungsbedürftigen behandlungsbedürftigen NNP cord-015369-72cjogxz 6591 1 oberflächlichen oberflächlichen NNP cord-015369-72cjogxz 6591 2 sternalen sternalen NNP cord-015369-72cjogxz 6591 3 Wundinfekten Wundinfekten NNP cord-015369-72cjogxz 6591 4 , , , cord-015369-72cjogxz 6591 5 an an DT cord-015369-72cjogxz 6591 6 der der NNP cord-015369-72cjogxz 6591 7 Beinwunde Beinwunde NNP cord-015369-72cjogxz 6591 8 war war NN cord-015369-72cjogxz 6591 9 die die VBP cord-015369-72cjogxz 6591 10 Inzidenz Inzidenz NNP cord-015369-72cjogxz 6591 11 für für IN cord-015369-72cjogxz 6591 12 Weichteilinfekte Weichteilinfekte NNP cord-015369-72cjogxz 6591 13 0,51 0,51 CD cord-015369-72cjogxz 6591 14 % % NN cord-015369-72cjogxz 6591 15 ( ( -LRB- cord-015369-72cjogxz 6591 16 n n NN cord-015369-72cjogxz 6591 17 ¼ ¼ NNP cord-015369-72cjogxz 6591 18 5 5 CD cord-015369-72cjogxz 6591 19 ) ) -RRB- cord-015369-72cjogxz 6591 20 , , , cord-015369-72cjogxz 6591 21 bei bei NNP cord-015369-72cjogxz 6591 22 diesen diesen NNP cord-015369-72cjogxz 6591 23 Patienten Patienten NNP cord-015369-72cjogxz 6591 24 wurden wurden VBD cord-015369-72cjogxz 6591 25 mit mit NNP cord-015369-72cjogxz 6591 26 einem einem NNP cord-015369-72cjogxz 6591 27 V.A.C.-System V.A.C.-System NNP cord-015369-72cjogxz 6591 28 behandelt behandelt NNP cord-015369-72cjogxz 6591 29 , , , cord-015369-72cjogxz 6591 30 in in IN cord-015369-72cjogxz 6591 31 einem einem NNP cord-015369-72cjogxz 6591 32 Fall Fall NNP cord-015369-72cjogxz 6591 33 musste musste NNP cord-015369-72cjogxz 6591 34 der der NNP cord-015369-72cjogxz 6591 35 Defekt Defekt NNP cord-015369-72cjogxz 6591 36 mit mit JJ cord-015369-72cjogxz 6591 37 einer einer NNP cord-015369-72cjogxz 6591 38 Spalthaut Spalthaut NNP cord-015369-72cjogxz 6591 39 gedeckt gedeckt NNS cord-015369-72cjogxz 6591 40 werden werden NNP cord-015369-72cjogxz 6591 41 . . . cord-015369-72cjogxz 6592 1 In in IN cord-015369-72cjogxz 6592 2 sechs sechs NNP cord-015369-72cjogxz 6592 3 Fällen Fällen NNP cord-015369-72cjogxz 6592 4 ( ( -LRB- cord-015369-72cjogxz 6592 5 0,62 0,62 CD cord-015369-72cjogxz 6592 6 % % NN cord-015369-72cjogxz 6592 7 ) ) -RRB- cord-015369-72cjogxz 6592 8 wurde wurde NNP cord-015369-72cjogxz 6592 9 eine eine NNP cord-015369-72cjogxz 6592 10 sterile sterile JJ cord-015369-72cjogxz 6592 11 Sternumdehiszenz Sternumdehiszenz NNP cord-015369-72cjogxz 6592 12 noch noch NNP cord-015369-72cjogxz 6592 13 am am NN cord-015369-72cjogxz 6592 14 Tag tag NN cord-015369-72cjogxz 6592 15 der der NN cord-015369-72cjogxz 6592 16 Wundrevision Wundrevision NNP cord-015369-72cjogxz 6592 17 recercliert recercliert NN cord-015369-72cjogxz 6592 18 . . . cord-015369-72cjogxz 6593 1 Bei Bei NNP cord-015369-72cjogxz 6593 2 keinem keinem NNP cord-015369-72cjogxz 6593 3 Patienten Patienten NNP cord-015369-72cjogxz 6593 4 wissen wissen NNP cord-015369-72cjogxz 6593 5 wir wir NNP cord-015369-72cjogxz 6593 6 von von NNP cord-015369-72cjogxz 6593 7 chronisch chronisch NNP cord-015369-72cjogxz 6593 8 offenen offenen NNP cord-015369-72cjogxz 6593 9 Wunden Wunden NNP cord-015369-72cjogxz 6593 10 . . . cord-015369-72cjogxz 6594 1 Die die VB cord-015369-72cjogxz 6594 2 Mortalität Mortalität NNP cord-015369-72cjogxz 6595 1 aufgrund aufgrund NNP cord-015369-72cjogxz 6595 2 von von NNP cord-015369-72cjogxz 6595 3 Wundinfekten Wundinfekten NNP cord-015369-72cjogxz 6595 4 war war NN cord-015369-72cjogxz 6595 5 0 0 CD cord-015369-72cjogxz 6595 6 % % NN cord-015369-72cjogxz 6595 7 . . . cord-015369-72cjogxz 6596 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6596 2 . . . cord-015369-72cjogxz 6597 1 Nach Nach NNP cord-015369-72cjogxz 6597 2 5 5 CD cord-015369-72cjogxz 6597 3 Jahren Jahren NNP cord-015369-72cjogxz 6597 4 kam kam NNP cord-015369-72cjogxz 6597 5 es es XX cord-015369-72cjogxz 6597 6 nicht nicht NNP cord-015369-72cjogxz 6597 7 zu zu NNP cord-015369-72cjogxz 6597 8 Resistenzen Resistenzen NNP cord-015369-72cjogxz 6597 9 . . . cord-015369-72cjogxz 6598 1 Die die VB cord-015369-72cjogxz 6598 2 Rate rate NN cord-015369-72cjogxz 6598 3 an an DT cord-015369-72cjogxz 6598 4 Wundinfektionen Wundinfektionen NNP cord-015369-72cjogxz 6598 5 ist ist NN cord-015369-72cjogxz 6598 6 erfreulich erfreulich NN cord-015369-72cjogxz 6598 7 gering gering NNP cord-015369-72cjogxz 6598 8 . . . cord-015369-72cjogxz 6599 1 Unverständlicherweise Unverständlicherweise NNP cord-015369-72cjogxz 6600 1 kommt kommt NNP cord-015369-72cjogxz 6600 2 dieses dieses NNP cord-015369-72cjogxz 6600 3 Grazer Grazer NNP cord-015369-72cjogxz 6600 4 antiobiotische antiobiotische NN cord-015369-72cjogxz 6600 5 Regime Regime NNP cord-015369-72cjogxz 6600 6 kaum kaum NNP cord-015369-72cjogxz 6600 7 zur zur NNP cord-015369-72cjogxz 6600 8 Anwendung Anwendung NNP cord-015369-72cjogxz 6600 9 . . . cord-015369-72cjogxz 6601 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6601 2 . . . cord-015369-72cjogxz 6602 1 Morbus Morbus NNP cord-015369-72cjogxz 6602 2 Castelman Castelman NNP cord-015369-72cjogxz 6602 3 ( ( -LRB- cord-015369-72cjogxz 6602 4 angiofollikuläre angiofollikuläre NNP cord-015369-72cjogxz 6602 5 Lymphknotenhyperplasie Lymphknotenhyperplasie NNP cord-015369-72cjogxz 6602 6 ) ) -RRB- cord-015369-72cjogxz 6603 1 ist ist NNP cord-015369-72cjogxz 6604 1 eine eine NNP cord-015369-72cjogxz 6604 2 seltene seltene NNP cord-015369-72cjogxz 6604 3 Erkrankung Erkrankung NNP cord-015369-72cjogxz 6604 4 vornehmlich vornehmlich NNP cord-015369-72cjogxz 6604 5 der der NNP cord-015369-72cjogxz 6604 6 cervikalen cervikalen NNP cord-015369-72cjogxz 6605 1 und und IN cord-015369-72cjogxz 6605 2 mediastinalen mediastinalen NNP cord-015369-72cjogxz 6605 3 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 6605 4 . . . cord-015369-72cjogxz 6606 1 Klinisch Klinisch NNP cord-015369-72cjogxz 6606 2 imponieren imponieren NNP cord-015369-72cjogxz 6607 1 Lymphknotenschwellung Lymphknotenschwellung NNP cord-015369-72cjogxz 6607 2 mit mit NNP cord-015369-72cjogxz 6607 3 B B NNP cord-015369-72cjogxz 6607 4 - - HYPH cord-015369-72cjogxz 6607 5 Symptomatik Symptomatik NNP cord-015369-72cjogxz 6607 6 , , , cord-015369-72cjogxz 6607 7 Splenomegalie Splenomegalie NNP cord-015369-72cjogxz 6607 8 und und IN cord-015369-72cjogxz 6607 9 Hepatomegalie Hepatomegalie NNP cord-015369-72cjogxz 6607 10 . . . cord-015369-72cjogxz 6608 1 Die die VB cord-015369-72cjogxz 6608 2 Diagnosesicherung Diagnosesicherung NNP cord-015369-72cjogxz 6608 3 erfolgt erfolgt NNP cord-015369-72cjogxz 6608 4 durch durch NNP cord-015369-72cjogxz 6608 5 Biopsie Biopsie NNP cord-015369-72cjogxz 6608 6 . . . cord-015369-72cjogxz 6609 1 Wir Wir NNP cord-015369-72cjogxz 6609 2 berichten berichten NNP cord-015369-72cjogxz 6609 3 über über NNP cord-015369-72cjogxz 6609 4 eine eine NNP cord-015369-72cjogxz 6609 5 24 24 CD cord-015369-72cjogxz 6609 6 jährige jährige NNP cord-015369-72cjogxz 6609 7 Patientin Patientin NNP cord-015369-72cjogxz 6609 8 , , , cord-015369-72cjogxz 6609 9 welche welche NNP cord-015369-72cjogxz 6609 10 nach nach NNP cord-015369-72cjogxz 6609 11 vorangegangenem vorangegangenem NNP cord-015369-72cjogxz 6610 1 respiratorischen respiratorischen NNP cord-015369-72cjogxz 6610 2 Infekt Infekt NNP cord-015369-72cjogxz 6610 3 akute akute NN cord-015369-72cjogxz 6610 4 Hämoptysen Hämoptysen NNP cord-015369-72cjogxz 6610 5 und und IN cord-015369-72cjogxz 6610 6 Dyspnoe Dyspnoe NNP cord-015369-72cjogxz 6610 7 zeigte zeigte NNP cord-015369-72cjogxz 6610 8 . . . cord-015369-72cjogxz 6611 1 Bronchoskopisch Bronchoskopisch NNP cord-015369-72cjogxz 6611 2 fanden fanden NNP cord-015369-72cjogxz 6611 3 sich sich NNP cord-015369-72cjogxz 6611 4 Zeichen Zeichen NNP cord-015369-72cjogxz 6611 5 einer einer NNP cord-015369-72cjogxz 6611 6 stattgehabten stattgehabten NNP cord-015369-72cjogxz 6611 7 Blutung Blutung NNP cord-015369-72cjogxz 6611 8 . . . cord-015369-72cjogxz 6612 1 I -PRON- PRP cord-015369-72cjogxz 6612 2 m be VBP cord-015369-72cjogxz 6612 3 Labor Labor NNP cord-015369-72cjogxz 6612 4 waren waren NNP cord-015369-72cjogxz 6612 5 Leukozytose Leukozytose NNP cord-015369-72cjogxz 6612 6 und und XX cord-015369-72cjogxz 6613 1 CRP CRP NNP cord-015369-72cjogxz 6613 2 Erhöhung Erhöhung NNP cord-015369-72cjogxz 6613 3 auffällig auffällig RB cord-015369-72cjogxz 6613 4 . . . cord-015369-72cjogxz 6614 1 Methodik Methodik NNP cord-015369-72cjogxz 6614 2 . . . cord-015369-72cjogxz 6615 1 I -PRON- PRP cord-015369-72cjogxz 6615 2 m be VBP cord-015369-72cjogxz 6616 1 Thorax Thorax NNP cord-015369-72cjogxz 6616 2 CT CT NNP cord-015369-72cjogxz 6616 3 fand fand NN cord-015369-72cjogxz 6616 4 sich sich NNP cord-015369-72cjogxz 6616 5 eine eine NNP cord-015369-72cjogxz 6616 6 ausgedehnte ausgedehnte NNP cord-015369-72cjogxz 6616 7 diffuse diffuse NN cord-015369-72cjogxz 6616 8 , , , cord-015369-72cjogxz 6616 9 tumoröse tumoröse NNP cord-015369-72cjogxz 6616 10 Infiltration Infiltration NNP cord-015369-72cjogxz 6616 11 des des FW cord-015369-72cjogxz 6616 12 oberen oberen NNP cord-015369-72cjogxz 6617 1 und und NNP cord-015369-72cjogxz 6617 2 mittleren mittleren NNP cord-015369-72cjogxz 6617 3 Mediastinums Mediastinums NNP cord-015369-72cjogxz 6617 4 und und VBD cord-015369-72cjogxz 6617 5 beider beider NN cord-015369-72cjogxz 6618 1 Hili Hili NNP cord-015369-72cjogxz 6618 2 mit mit NNP cord-015369-72cjogxz 6618 3 Umscheidung Umscheidung NNP cord-015369-72cjogxz 6619 1 der der NNP cord-015369-72cjogxz 6619 2 supraaortalen supraaortalen NNP cord-015369-72cjogxz 6620 1 Ä Ä NNP cord-015369-72cjogxz 6620 2 ste ste NNP cord-015369-72cjogxz 6620 3 , , , cord-015369-72cjogxz 6620 4 der der NNP cord-015369-72cjogxz 6620 5 Aorta Aorta NNP cord-015369-72cjogxz 6620 6 ascendens ascenden NNS cord-015369-72cjogxz 6620 7 , , , cord-015369-72cjogxz 6620 8 Vena Vena NNP cord-015369-72cjogxz 6620 9 cava cava NNP cord-015369-72cjogxz 6620 10 superior superior NNP cord-015369-72cjogxz 6620 11 sowie sowie NNP cord-015369-72cjogxz 6620 12 der der NNP cord-015369-72cjogxz 6620 13 beiden beiden NNP cord-015369-72cjogxz 6620 14 Vorhöfe Vorhöfe NNP cord-015369-72cjogxz 6620 15 . . . cord-015369-72cjogxz 6621 1 Infolge Infolge NNP cord-015369-72cjogxz 6621 2 völliger völliger NN cord-015369-72cjogxz 6622 1 Einmauerung Einmauerung NNP cord-015369-72cjogxz 6622 2 des des FW cord-015369-72cjogxz 6622 3 rechten rechten NNP cord-015369-72cjogxz 6622 4 Pulmonalarterienhauptstammes Pulmonalarterienhauptstammes NNP cord-015369-72cjogxz 6622 5 bestand bestand NNP cord-015369-72cjogxz 6622 6 rechts rechts NNP cord-015369-72cjogxz 6622 7 keine keine NNP cord-015369-72cjogxz 6622 8 Perfusion Perfusion NNP cord-015369-72cjogxz 6622 9 . . . cord-015369-72cjogxz 6623 1 Keine Keine NNP cord-015369-72cjogxz 6623 2 dieser dieser NNP cord-015369-72cjogxz 6623 3 Strukturen Strukturen NNP cord-015369-72cjogxz 6623 4 zeigte zeigte NNP cord-015369-72cjogxz 6624 1 eine eine NNP cord-015369-72cjogxz 6624 2 Speicherung Speicherung NNP cord-015369-72cjogxz 6625 1 i -PRON- PRP cord-015369-72cjogxz 6625 2 m be VBP cord-015369-72cjogxz 6625 3 PET PET NNP cord-015369-72cjogxz 6625 4 , , , cord-015369-72cjogxz 6626 1 nur nur NNP cord-015369-72cjogxz 6626 2 an an DT cord-015369-72cjogxz 6626 3 der der NNP cord-015369-72cjogxz 6626 4 Mesenterialwurzel Mesenterialwurzel NNP cord-015369-72cjogxz 6626 5 fand fand NN cord-015369-72cjogxz 6626 6 sich sich NNP cord-015369-72cjogxz 6626 7 ein ein NNP cord-015369-72cjogxz 6626 8 hypermetaboler hypermetaboler NN cord-015369-72cjogxz 6626 9 Herd Herd NNP cord-015369-72cjogxz 6626 10 . . . cord-015369-72cjogxz 6627 1 Der Der NNP cord-015369-72cjogxz 6627 2 Versuch Versuch NNP cord-015369-72cjogxz 6627 3 einer einer NNP cord-015369-72cjogxz 6628 1 Mediastinoskopie Mediastinoskopie NNP cord-015369-72cjogxz 6628 2 zur zur NNP cord-015369-72cjogxz 6628 3 Diagnosesicherung Diagnosesicherung NNP cord-015369-72cjogxz 6628 4 scheiterte scheiterte VBZ cord-015369-72cjogxz 6628 5 an an DT cord-015369-72cjogxz 6628 6 der der NN cord-015369-72cjogxz 6628 7 fehlenden fehlenden JJ cord-015369-72cjogxz 6629 1 Darstellbarkeit Darstellbarkeit NNP cord-015369-72cjogxz 6629 2 der der NNP cord-015369-72cjogxz 6629 3 Strukturen Strukturen NNP cord-015369-72cjogxz 6630 1 i -PRON- PRP cord-015369-72cjogxz 6630 2 m be VBP cord-015369-72cjogxz 6630 3 extrem extrem NNP cord-015369-72cjogxz 6630 4 derb derb NNP cord-015369-72cjogxz 6630 5 - - HYPH cord-015369-72cjogxz 6630 6 fibrotischen fibrotischen NNP cord-015369-72cjogxz 6630 7 Gewerbe Gewerbe NNP cord-015369-72cjogxz 6630 8 . . . cord-015369-72cjogxz 6631 1 Ü ü NN cord-015369-72cjogxz 6632 1 ber ber NNP cord-015369-72cjogxz 6632 2 Thoracotomie Thoracotomie NNP cord-015369-72cjogxz 6632 3 gelang gelang NNP cord-015369-72cjogxz 6632 4 es es NNP cord-015369-72cjogxz 6632 5 aus aus NNP cord-015369-72cjogxz 6632 6 einzelnen einzelnen NNP cord-015369-72cjogxz 6633 1 , , , cord-015369-72cjogxz 6633 2 in in IN cord-015369-72cjogxz 6633 3 die die JJ cord-015369-72cjogxz 6633 4 fibrösen fibrösen NNP cord-015369-72cjogxz 6633 5 Massen Massen NNP cord-015369-72cjogxz 6633 6 eingelagerten eingelagerten NNP cord-015369-72cjogxz 6633 7 hilären hilären NNP cord-015369-72cjogxz 6633 8 Lymphknoten Lymphknoten NNP cord-015369-72cjogxz 6633 9 eine eine NNP cord-015369-72cjogxz 6634 1 Diagnose diagnose VB cord-015369-72cjogxz 6634 2 zu zu NNP cord-015369-72cjogxz 6634 3 stellen stellen NNP cord-015369-72cjogxz 6634 4 . . . cord-015369-72cjogxz 6635 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6635 2 . . . cord-015369-72cjogxz 6636 1 Es Es NNP cord-015369-72cjogxz 6636 2 fand fand NNP cord-015369-72cjogxz 6636 3 sich sich NNP cord-015369-72cjogxz 6636 4 die die NNP cord-015369-72cjogxz 6636 5 seltene seltene NNP cord-015369-72cjogxz 6636 6 , , , cord-015369-72cjogxz 6636 7 plasmazellreiche plasmazellreiche NNP cord-015369-72cjogxz 6636 8 Variante Variante NNP cord-015369-72cjogxz 6636 9 des des FW cord-015369-72cjogxz 6636 10 Mb Mb NNP cord-015369-72cjogxz 6636 11 . . . cord-015369-72cjogxz 6637 1 Castleman Castleman NNP cord-015369-72cjogxz 6637 2 mit mit VBD cord-015369-72cjogxz 6637 3 ausgeprägter ausgeprägter NN cord-015369-72cjogxz 6637 4 Hyalinisierung Hyalinisierung NNP cord-015369-72cjogxz 6637 5 und und IN cord-015369-72cjogxz 6637 6 Fibrosierung Fibrosierung NNP cord-015369-72cjogxz 6637 7 . . . cord-015369-72cjogxz 6638 1 Diese Diese NNP cord-015369-72cjogxz 6638 2 Form Form NNP cord-015369-72cjogxz 6638 3 ist ist NN cord-015369-72cjogxz 6638 4 multifokal multifokal NN cord-015369-72cjogxz 6639 1 und und NNP cord-015369-72cjogxz 6639 2 zeigt zeigt NNP cord-015369-72cjogxz 6639 3 verstärkte verstärkte NNP cord-015369-72cjogxz 6639 4 IL IL NNP cord-015369-72cjogxz 6639 5 6 6 CD cord-015369-72cjogxz 6639 6 Expression expression NN cord-015369-72cjogxz 6639 7 und und IN cord-015369-72cjogxz 6639 8 in in IN cord-015369-72cjogxz 6639 9 deren deren NNP cord-015369-72cjogxz 6639 10 Folge Folge NNP cord-015369-72cjogxz 6639 11 unspezifische unspezifische NN cord-015369-72cjogxz 6639 12 Entzündungszeichen Entzündungszeichen NNP cord-015369-72cjogxz 6639 13 . . . cord-015369-72cjogxz 6640 1 Eine Eine NNP cord-015369-72cjogxz 6640 2 Koinfektion Koinfektion NNP cord-015369-72cjogxz 6640 3 mit mit NNP cord-015369-72cjogxz 6640 4 HHV HHV NNP cord-015369-72cjogxz 6640 5 8 8 CD cord-015369-72cjogxz 6640 6 bzw bzw NNP cord-015369-72cjogxz 6640 7 . . . cord-015369-72cjogxz 6641 1 mit mit NNP cord-015369-72cjogxz 6641 2 HIV HIV NNP cord-015369-72cjogxz 6642 1 ( ( -LRB- cord-015369-72cjogxz 6642 2 in in IN cord-015369-72cjogxz 6642 3 ca ca NNP cord-015369-72cjogxz 6642 4 . . . cord-015369-72cjogxz 6643 1 50 50 CD cord-015369-72cjogxz 6643 2 % % NN cord-015369-72cjogxz 6643 3 zu zu NNP cord-015369-72cjogxz 6643 4 beobachten beobachten NNP cord-015369-72cjogxz 6643 5 ) ) -RRB- cord-015369-72cjogxz 6643 6 konnte konnte NNP cord-015369-72cjogxz 6643 7 ausgeschlossen ausgeschlossen NNP cord-015369-72cjogxz 6643 8 werden werden NNP cord-015369-72cjogxz 6643 9 . . . cord-015369-72cjogxz 6644 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6644 2 . . . cord-015369-72cjogxz 6645 1 Durch Durch NNP cord-015369-72cjogxz 6645 2 die die VBP cord-015369-72cjogxz 6646 1 Einleitung Einleitung NNP cord-015369-72cjogxz 6646 2 einer einer NNP cord-015369-72cjogxz 6647 1 Therapie Therapie NNP cord-015369-72cjogxz 6647 2 mit mit NNP cord-015369-72cjogxz 6647 3 einem einem NNP cord-015369-72cjogxz 6647 4 monoklonalen monoklonalen NNP cord-015369-72cjogxz 6647 5 chimären chimären NNP cord-015369-72cjogxz 6647 6 Antikörper Antikörper NNP cord-015369-72cjogxz 6648 1 ( ( -LRB- cord-015369-72cjogxz 6648 2 Rituximab Rituximab NNP cord-015369-72cjogxz 6648 3 ; ; : cord-015369-72cjogxz 6648 4 Mabthera Mabthera NNP cord-015369-72cjogxz 6648 5 + + CC cord-015369-72cjogxz 6648 6 ) ) -RRB- cord-015369-72cjogxz 6648 7 wurden wurden NNP cord-015369-72cjogxz 6648 8 eine eine NNP cord-015369-72cjogxz 6648 9 signifikante signifikante NNP cord-015369-72cjogxz 6649 1 Besserung Besserung NNP cord-015369-72cjogxz 6649 2 der der NNP cord-015369-72cjogxz 6650 1 klinischen klinischen NNP cord-015369-72cjogxz 6650 2 Symptomatik Symptomatik NNP cord-015369-72cjogxz 6650 3 sowie sowie NNP cord-015369-72cjogxz 6650 4 eine eine NNP cord-015369-72cjogxz 6650 5 deutliche deutliche NN cord-015369-72cjogxz 6650 6 Befundregredienz Befundregredienz NNP cord-015369-72cjogxz 6650 7 erreicht erreicht NNP cord-015369-72cjogxz 6650 8 . . . cord-015369-72cjogxz 6651 1 Germany Germany NNP cord-015369-72cjogxz 6651 2 Ziel Ziel NNP cord-015369-72cjogxz 6651 3 der der NNP cord-015369-72cjogxz 6651 4 Untersuchung Untersuchung NNP cord-015369-72cjogxz 6651 5 war war NN cord-015369-72cjogxz 6651 6 es es NN cord-015369-72cjogxz 6651 7 , , , cord-015369-72cjogxz 6651 8 Machbarkeit Machbarkeit NNP cord-015369-72cjogxz 6651 9 , , , cord-015369-72cjogxz 6651 10 Therapieergebnisse Therapieergebnisse NNP cord-015369-72cjogxz 6651 11 & & CC cord-015369-72cjogxz 6651 12 , , , cord-015369-72cjogxz 6651 13 Outcome Outcome NNP cord-015369-72cjogxz 6651 14 ' ' '' cord-015369-72cjogxz 6651 15 ' ' '' cord-015369-72cjogxz 6651 16 der der NNP cord-015369-72cjogxz 6651 17 endoskopischen endoskopischen NNP cord-015369-72cjogxz 6651 18 Papillektomie Papillektomie NNP cord-015369-72cjogxz 6651 19 zu zu NNP cord-015369-72cjogxz 6651 20 untersuchen untersuchen NNP cord-015369-72cjogxz 6651 21 . . . cord-015369-72cjogxz 6652 1 Methodik Methodik NNP cord-015369-72cjogxz 6652 2 . . . cord-015369-72cjogxz 6653 1 Ü Ü NNP cord-015369-72cjogxz 6653 2 ber ber NNP cord-015369-72cjogxz 6653 3 einen einen NNP cord-015369-72cjogxz 6653 4 definierten definierten VBN cord-015369-72cjogxz 6653 5 Behandlungszeitraum Behandlungszeitraum NNP cord-015369-72cjogxz 6653 6 wurden wurden VBD cord-015369-72cjogxz 6653 7 alle alle NNP cord-015369-72cjogxz 6653 8 konsekutiven konsekutiven NNP cord-015369-72cjogxz 6653 9 Patienten Patienten NNP cord-015369-72cjogxz 6653 10 mit mit NNP cord-015369-72cjogxz 6653 11 Tumor Tumor NNP cord-015369-72cjogxz 6653 12 - - HYPH cord-015369-72cjogxz 6653 13 ähnlichen ähnlichen NNP cord-015369-72cjogxz 6653 14 Papillenläsionen Papillenläsionen NNP cord-015369-72cjogxz 6653 15 mit mit NNP cord-015369-72cjogxz 6653 16 möglicher möglicher NNP cord-015369-72cjogxz 6653 17 endoskopischer endoskopischer NNP cord-015369-72cjogxz 6653 18 Papillektomie Papillektomie NNP cord-015369-72cjogxz 6653 19 in in IN cord-015369-72cjogxz 6653 20 diese diese NNP cord-015369-72cjogxz 6653 21 systematische systematische NNP cord-015369-72cjogxz 6653 22 klinische klinische NNP cord-015369-72cjogxz 6653 23 , , , cord-015369-72cjogxz 6653 24 Bicenter''-Beobachtungsstudie Bicenter''-Beobachtungsstudie NNP cord-015369-72cjogxz 6653 25 einbezogen einbezogen NNP cord-015369-72cjogxz 6653 26 & & CC cord-015369-72cjogxz 6653 27 in in IN cord-015369-72cjogxz 6653 28 4 4 CD cord-015369-72cjogxz 6653 29 Gruppen Gruppen NNP cord-015369-72cjogxz 6653 30 entsprechend entsprechend NNP cord-015369-72cjogxz 6653 31 des des NNP cord-015369-72cjogxz 6653 32 endoskopischen endoskopischen NNP cord-015369-72cjogxz 6653 33 & & CC cord-015369-72cjogxz 6653 34 EUS EUS NNP cord-015369-72cjogxz 6653 35 - - HYPH cord-015369-72cjogxz 6653 36 Befundes Befundes NNP cord-015369-72cjogxz 6654 1 sowie sowie NNP cord-015369-72cjogxz 6654 2 der der NNP cord-015369-72cjogxz 6654 3 pathohistologischen pathohistologischen NNP cord-015369-72cjogxz 6655 1 Diagnose diagnose VB cord-015369-72cjogxz 6655 2 eingeteilt eingeteilt NN cord-015369-72cjogxz 6655 3 . . . cord-015369-72cjogxz 6656 1 Machbarkeit Machbarkeit NNP cord-015369-72cjogxz 6656 2 & & CC cord-015369-72cjogxz 6656 3 Behandlungsergebnisse Behandlungsergebnisse NNP cord-015369-72cjogxz 6656 4 wurden wurden NNP cord-015369-72cjogxz 6656 5 durch durch NNP cord-015369-72cjogxz 6656 6 R0-Resektionsrate r0-resektionsrate NN cord-015369-72cjogxz 6656 7 , , , cord-015369-72cjogxz 6656 8 Morbidität Morbidität NNP cord-015369-72cjogxz 6656 9 ( ( -LRB- cord-015369-72cjogxz 6656 10 z. z. NNP cord-015369-72cjogxz 6657 1 B. B. NNP cord-015369-72cjogxz 6657 2 Rate Rate NNP cord-015369-72cjogxz 6657 3 / / SYM cord-015369-72cjogxz 6657 4 Spektrum Spektrum NNP cord-015369-72cjogxz 6657 5 von von NNP cord-015369-72cjogxz 6657 6 Komplikationen Komplikationen NNP cord-015369-72cjogxz 6657 7 ) ) -RRB- cord-015369-72cjogxz 6657 8 & & CC cord-015369-72cjogxz 6657 9 Mortalität Mortalität NNP cord-015369-72cjogxz 6657 10 charakterisiert charakterisiert NN cord-015369-72cjogxz 6657 11 ; ; . cord-015369-72cjogxz 6658 1 Outcome outcome NN cord-015369-72cjogxz 6658 2 wurde wurde NN cord-015369-72cjogxz 6658 3 durch durch NNP cord-015369-72cjogxz 6658 4 Rezidivrate Rezidivrate NNP cord-015369-72cjogxz 6658 5 & & CC cord-015369-72cjogxz 6658 6 Tumor Tumor NNP cord-015369-72cjogxz 6658 7 - - HYPH cord-015369-72cjogxz 6658 8 freies freies NNP cord-015369-72cjogxz 6658 9 Ü ü NN cord-015369-72cjogxz 6658 10 berleben berleben NN cord-015369-72cjogxz 6658 11 eingeschätzt eingeschätzt JJ cord-015369-72cjogxz 6658 12 Jahre Jahre NNP cord-015369-72cjogxz 6658 13 ) ) -RRB- cord-015369-72cjogxz 6659 1 eingeschlossen eingeschlossen NNP cord-015369-72cjogxz 6659 2 . . . cord-015369-72cjogxz 6660 1 Vor Vor NNP cord-015369-72cjogxz 6660 2 der der NNP cord-015369-72cjogxz 6660 3 Papillektomie Papillektomie NNP cord-015369-72cjogxz 6660 4 wurde wurde NNP cord-015369-72cjogxz 6660 5 die die VBP cord-015369-72cjogxz 6660 6 EUS eus NN cord-015369-72cjogxz 6660 7 in in IN cord-015369-72cjogxz 6660 8 4/5 4/5 CD cord-015369-72cjogxz 6660 9 ( ( -LRB- cord-015369-72cjogxz 6660 10 79,6 79,6 CD cord-015369-72cjogxz 6660 11 % % NN cord-015369-72cjogxz 6660 12 ; ; : cord-015369-72cjogxz 6660 13 n n NN cord-015369-72cjogxz 6660 14 ¼ ¼ NNP cord-015369-72cjogxz 6660 15 43 43 CD cord-015369-72cjogxz 6660 16 ) ) -RRB- cord-015369-72cjogxz 6660 17 der der NNP cord-015369-72cjogxz 6660 18 Patienten Patienten NNP cord-015369-72cjogxz 6660 19 durchgeführt durchgeführt NN cord-015369-72cjogxz 6660 20 Gr.2 Gr.2 NNP cord-015369-72cjogxz 6661 1 ( ( -LRB- cord-015369-72cjogxz 6661 2 Karzinom Karzinom NNP cord-015369-72cjogxz 6661 3 / / SYM cord-015369-72cjogxz 6661 4 neuroendokriner neuroendokriner NN cord-015369-72cjogxz 6661 5 Tumor tumor NN cord-015369-72cjogxz 6661 6 , , , cord-015369-72cjogxz 6661 7 n n NN cord-015369-72cjogxz 6661 8 ¼ ¼ NNP cord-015369-72cjogxz 6661 9 18 18 CD cord-015369-72cjogxz 6661 10 ) ) -RRB- cord-015369-72cjogxz 6661 11 : : : cord-015369-72cjogxz 6662 1 55,6 55,6 CD cord-015369-72cjogxz 6662 2 % % NN cord-015369-72cjogxz 6662 3 ( ( -LRB- cord-015369-72cjogxz 6662 4 n n NN cord-015369-72cjogxz 6662 5 ¼ ¼ NNP cord-015369-72cjogxz 6662 6 10 10 CD cord-015369-72cjogxz 6662 7 ) ) -RRB- cord-015369-72cjogxz 6662 8 mit mit NNP cord-015369-72cjogxz 6662 9 R0-Resektion r0-resektion NN cord-015369-72cjogxz 6663 1 Gr.3 Gr.3 NNP cord-015369-72cjogxz 6664 1 ( ( -LRB- cord-015369-72cjogxz 6664 2 Adenomyomatosis Adenomyomatosis NNP cord-015369-72cjogxz 6664 3 , , , cord-015369-72cjogxz 6664 4 n n NN cord-015369-72cjogxz 6664 5 ¼ ¼ NNP cord-015369-72cjogxz 6664 6 4 4 CD cord-015369-72cjogxz 6664 7 ) ) -RRB- cord-015369-72cjogxz 6664 8 . . . cord-015369-72cjogxz 6665 1 Gr.4 Gr.4 NNP cord-015369-72cjogxz 6665 2 ( ( -LRB- cord-015369-72cjogxz 6665 3 nicht nicht NNP cord-015369-72cjogxz 6665 4 einführbarer einführbarer NNP cord-015369-72cjogxz 6665 5 Katheter Katheter NNP cord-015369-72cjogxz 6665 6 in in IN cord-015369-72cjogxz 6665 7 die die NN cord-015369-72cjogxz 6666 1 Papille Papille NNP cord-015369-72cjogxz 6666 2 Bei Bei NNP cord-015369-72cjogxz 6666 3 Hochrisikopatienten Hochrisikopatienten NNP cord-015369-72cjogxz 6666 4 mit mit NNP cord-015369-72cjogxz 6666 5 Papillenkarzinom Papillenkarzinom NNP cord-015369-72cjogxz 6666 6 jedoch jedoch NNP cord-015369-72cjogxz 6666 7 ohne ohne NNP cord-015369-72cjogxz 6666 8 Hinweise Hinweise NNP cord-015369-72cjogxz 6667 1 auf auf NNP cord-015369-72cjogxz 6667 2 ein ein NNP cord-015369-72cjogxz 6667 3 tief tief NNP cord-015369-72cjogxz 6667 4 infiltrierendes infiltrierendes NNP cord-015369-72cjogxz 6668 1 Tumorwachstum Tumorwachstum NNP cord-015369-72cjogxz 6668 2 kann kann NNP cord-015369-72cjogxz 6668 3 sie sie NNP cord-015369-72cjogxz 6668 4 als als NNP cord-015369-72cjogxz 6668 5 sinnvolle sinnvolle NNP cord-015369-72cjogxz 6668 6 Therapieoption Therapieoption NNP cord-015369-72cjogxz 6668 7 mit mit NNP cord-015369-72cjogxz 6668 8 niedrigem niedrigem NNP cord-015369-72cjogxz 6668 9 Risiko Risiko NNP cord-015369-72cjogxz 6668 10 & & CC cord-015369-72cjogxz 6668 11 einer einer NNP cord-015369-72cjogxz 6668 12 ca ca NNP cord-015369-72cjogxz 6668 13 . . . cord-015369-72cjogxz 6669 1 80 80 CD cord-015369-72cjogxz 6669 2 % % NN cord-015369-72cjogxz 6670 1 -Wahrscheinlichkeit -Wahrscheinlichkeit . cord-015369-72cjogxz 6671 1 hinsichtlich hinsichtlich NNP cord-015369-72cjogxz 6671 2 Rezidivfreiheit Rezidivfreiheit NNP cord-015369-72cjogxz 6671 3 angesehen angesehen NNP cord-015369-72cjogxz 6671 4 werden werden NNP cord-015369-72cjogxz 6671 5 , , , cord-015369-72cjogxz 6671 6 wenn wenn NNP cord-015369-72cjogxz 6671 7 R0 R0 NNP cord-015369-72cjogxz 6671 8 erreicht erreicht NNP cord-015369-72cjogxz 6671 9 wird wird NNP cord-015369-72cjogxz 6671 10 Die Die NNP cord-015369-72cjogxz 6672 1 Toxizität Toxizität NNP cord-015369-72cjogxz 6672 2 des des NNP cord-015369-72cjogxz 6672 3 Antikörpers Antikörpers NNP cord-015369-72cjogxz 6672 4 ( ( -LRB- cord-015369-72cjogxz 6672 5 Ak Ak NNP cord-015369-72cjogxz 6672 6 ) ) -RRB- cord-015369-72cjogxz 6672 7 unterscheidet unterscheidet NNP cord-015369-72cjogxz 6672 8 sich sich NNP cord-015369-72cjogxz 6672 9 von von NNP cord-015369-72cjogxz 6672 10 der der NNP cord-015369-72cjogxz 6672 11 traditionellen traditionellen NNP cord-015369-72cjogxz 6672 12 Chemotherapie Chemotherapie NNP cord-015369-72cjogxz 6672 13 . . . cord-015369-72cjogxz 6673 1 Eine Eine NNP cord-015369-72cjogxz 6673 2 zwar zwar NNP cord-015369-72cjogxz 6673 3 seltene seltene NN cord-015369-72cjogxz 6674 1 aber aber NNP cord-015369-72cjogxz 6674 2 schwerwiegende schwerwiegende NNP cord-015369-72cjogxz 6674 3 Ak Ak NNP cord-015369-72cjogxz 6674 4 - - HYPH cord-015369-72cjogxz 6674 5 spezifische spezifische NNP cord-015369-72cjogxz 6675 1 Komplikation komplikation NN cord-015369-72cjogxz 6675 2 ist ist NN cord-015369-72cjogxz 6675 3 die die VBP cord-015369-72cjogxz 6675 4 gastrointestinale gastrointestinale NN cord-015369-72cjogxz 6675 5 ( ( -LRB- cord-015369-72cjogxz 6675 6 GI GI NNP cord-015369-72cjogxz 6675 7 ) ) -RRB- cord-015369-72cjogxz 6675 8 Perforation Perforation NNP cord-015369-72cjogxz 6675 9 , , , cord-015369-72cjogxz 6675 10 die die VBP cord-015369-72cjogxz 6675 11 mit mit NNP cord-015369-72cjogxz 6675 12 hoher hoher NNP cord-015369-72cjogxz 6675 13 Morbidität Morbidität NNP cord-015369-72cjogxz 6675 14 / / SYM cord-015369-72cjogxz 6675 15 Letalität Letalität NNP cord-015369-72cjogxz 6675 16 einhergeht einhergeht NN cord-015369-72cjogxz 6675 17 . . . cord-015369-72cjogxz 6676 1 Das Das NNP cord-015369-72cjogxz 6676 2 Ziel Ziel NNP cord-015369-72cjogxz 6676 3 bestand bestand NNP cord-015369-72cjogxz 6676 4 darin darin NNP cord-015369-72cjogxz 6676 5 , , , cord-015369-72cjogxz 6676 6 an an DT cord-015369-72cjogxz 6676 7 Hand Hand NNP cord-015369-72cjogxz 6676 8 eigener eigener NN cord-015369-72cjogxz 6676 9 exemplarischer exemplarischer NN cord-015369-72cjogxz 6676 10 und und XX cord-015369-72cjogxz 6676 11 publizierter publizierter NNP cord-015369-72cjogxz 6676 12 Erfahrungen Erfahrungen NNP cord-015369-72cjogxz 6676 13 Befund Befund NNP cord-015369-72cjogxz 6676 14 - - HYPH cord-015369-72cjogxz 6676 15 bezogene bezogene NNP cord-015369-72cjogxz 6677 1 Besonderheiten Besonderheiten NNP cord-015369-72cjogxz 6677 2 dieser dieser NNP cord-015369-72cjogxz 6677 3 außergewöhnlichen außergewöhnlichen NNP cord-015369-72cjogxz 6678 1 Pathogenese Pathogenese NNP cord-015369-72cjogxz 6679 1 einer einer NNP cord-015369-72cjogxz 6679 2 perforationsbedingten perforationsbedingten NNP cord-015369-72cjogxz 6679 3 Peritonitis Peritonitis NNP cord-015369-72cjogxz 6679 4 nach nach NNP cord-015369-72cjogxz 6679 5 Ak Ak NNP cord-015369-72cjogxz 6679 6 - - HYPH cord-015369-72cjogxz 6679 7 Therapie Therapie NNP cord-015369-72cjogxz 6679 8 einschließlich einschließlich NNP cord-015369-72cjogxz 6679 9 therapeutischem therapeutischem NN cord-015369-72cjogxz 6679 10 , , , cord-015369-72cjogxz 6679 11 Outcome Outcome NNP cord-015369-72cjogxz 6679 12 ' ' '' cord-015369-72cjogxz 6679 13 ' ' '' cord-015369-72cjogxz 6679 14 darzustellen darzustellen NNP cord-015369-72cjogxz 6679 15 . . . cord-015369-72cjogxz 6680 1 Methodik Methodik NNP cord-015369-72cjogxz 6680 2 . . . cord-015369-72cjogxz 6681 1 Es Es NNP cord-015369-72cjogxz 6681 2 wurden wurden NNP cord-015369-72cjogxz 6682 1 Patienten Patienten NNP cord-015369-72cjogxz 6682 2 mit mit VBP cord-015369-72cjogxz 6682 3 einer einer NNP cord-015369-72cjogxz 6682 4 Bevacizumab Bevacizumab NNP cord-015369-72cjogxz 6682 5 - - HYPH cord-015369-72cjogxz 6682 6 induzierten induzierten NNP cord-015369-72cjogxz 6682 7 perforationsbedingten perforationsbedingten NNP cord-015369-72cjogxz 6682 8 Peritonitis Peritonitis NNP cord-015369-72cjogxz 6682 9 seit seit NNP cord-015369-72cjogxz 6682 10 klinischer klinischer NNP cord-015369-72cjogxz 6682 11 Einführung Einführung NNP cord-015369-72cjogxz 6682 12 ( ( -LRB- cord-015369-72cjogxz 6682 13 i i NN cord-015369-72cjogxz 6682 14 ) ) -RRB- cord-015369-72cjogxz 6682 15 aus aus NNP cord-015369-72cjogxz 6682 16 dem dem NNP cord-015369-72cjogxz 6682 17 eigenen eigenen NNP cord-015369-72cjogxz 6682 18 Patientenklientel Patientenklientel NNP cord-015369-72cjogxz 6682 19 recherchiert recherchiert NN cord-015369-72cjogxz 6682 20 ( ( -LRB- cord-015369-72cjogxz 6682 21 Design design NN cord-015369-72cjogxz 6682 22 : : : cord-015369-72cjogxz 6682 23 prospektive prospektive NNP cord-015369-72cjogxz 6682 24 Fallserie Fallserie NNP cord-015369-72cjogxz 6682 25 ) ) -RRB- cord-015369-72cjogxz 6682 26 , , , cord-015369-72cjogxz 6682 27 ( ( -LRB- cord-015369-72cjogxz 6682 28 ii ii NN cord-015369-72cjogxz 6682 29 ) ) -RRB- cord-015369-72cjogxz 6683 1 Literaturangaben Literaturangaben NNP cord-015369-72cjogxz 6683 2 gegenübergestellt gegenübergestellt NNP cord-015369-72cjogxz 6683 3 ( ( -LRB- cord-015369-72cjogxz 6683 4 historische[retrospektive historische[retrospektive JJ cord-015369-72cjogxz 6683 5 ] ] -RRB- cord-015369-72cjogxz 6684 1 Vergleichsgruppe Vergleichsgruppe NNP cord-015369-72cjogxz 6684 2 ) ) -RRB- cord-015369-72cjogxz 6684 3 und und RB cord-015369-72cjogxz 6685 1 ( ( -LRB- cord-015369-72cjogxz 6685 2 iii iii NNP cord-015369-72cjogxz 6685 3 ) ) -RRB- cord-015369-72cjogxz 6685 4 hinsichtlich hinsichtlich NNP cord-015369-72cjogxz 6685 5 der der NNP cord-015369-72cjogxz 6685 6 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6685 7 des des NNP cord-015369-72cjogxz 6686 1 chirurgischen chirurgischen NNP cord-015369-72cjogxz 6686 2 Managements Managements NNP cord-015369-72cjogxz 6686 3 Frauen Frauen NNP cord-015369-72cjogxz 6686 4 : : : cord-015369-72cjogxz 6686 5 n n NN cord-015369-72cjogxz 6686 6 ¼ ¼ CD cord-015369-72cjogxz 6686 7 2 2 CD cord-015369-72cjogxz 6687 1 ; ; : cord-015369-72cjogxz 6687 2 Geschlechtsverhältnis Geschlechtsverhältnis NNP cord-015369-72cjogxz 6687 3 : : : cord-015369-72cjogxz 6688 1 m m NNP cord-015369-72cjogxz 6688 2 : : : cord-015369-72cjogxz 6688 3 w w NNP cord-015369-72cjogxz 6688 4 ¼ ¼ NNP cord-015369-72cjogxz 6688 5 1:1 1:1 CD cord-015369-72cjogxz 6688 6 ) ) -RRB- cord-015369-72cjogxz 6688 7 . . . cord-015369-72cjogxz 6689 1 Die die VB cord-015369-72cjogxz 6689 2 durchschnittliche durchschnittliche NNP cord-015369-72cjogxz 6689 3 Behandlungsdauer Behandlungsdauer NNP cord-015369-72cjogxz 6690 1 bis bis NNP cord-015369-72cjogxz 6690 2 zum zum NNP cord-015369-72cjogxz 6690 3 Auftreten Auftreten NNP cord-015369-72cjogxz 6690 4 der der NNP cord-015369-72cjogxz 6690 5 Komplikation Komplikation NNP cord-015369-72cjogxz 6690 6 betrug betrug NNP cord-015369-72cjogxz 6690 7 durchschnittlich durchschnittlich NNP cord-015369-72cjogxz 6690 8 70d 70d NNP cord-015369-72cjogxz 6691 1 Patienten Patienten NNP cord-015369-72cjogxz 6691 2 verstarben verstarben NN cord-015369-72cjogxz 6691 3 ohne ohne NNP cord-015369-72cjogxz 6691 4 operative operative NN cord-015369-72cjogxz 6691 5 Versorgung Versorgung NNP cord-015369-72cjogxz 6691 6 an an DT cord-015369-72cjogxz 6691 7 den den NNP cord-015369-72cjogxz 6691 8 Peritonitisfolgen Peritonitisfolgen NNP cord-015369-72cjogxz 6691 9 . . . cord-015369-72cjogxz 6692 1 Die die VB cord-015369-72cjogxz 6692 2 perioperative perioperative JJ cord-015369-72cjogxz 6692 3 Gesamtmorbidität Gesamtmorbidität NNP cord-015369-72cjogxz 6692 4 betrug betrug JJ cord-015369-72cjogxz 6693 1 73,3 73,3 CD cord-015369-72cjogxz 6693 2 % % NN cord-015369-72cjogxz 6693 3 ( ( -LRB- cord-015369-72cjogxz 6693 4 n n NN cord-015369-72cjogxz 6693 5 ¼ ¼ NNP cord-015369-72cjogxz 6693 6 11/15 11/15 CD cord-015369-72cjogxz 6693 7 ) ) -RRB- cord-015369-72cjogxz 6694 1 In in IN cord-015369-72cjogxz 6694 2 allen allen NNP cord-015369-72cjogxz 6694 3 Fällen Fällen NNP cord-015369-72cjogxz 6694 4 mit mit JJ cord-015369-72cjogxz 6694 5 primärer primärer NN cord-015369-72cjogxz 6694 6 Anastomose Anastomose NNP cord-015369-72cjogxz 6694 7 ( ( -LRB- cord-015369-72cjogxz 6694 8 n n NN cord-015369-72cjogxz 6694 9 ¼ ¼ NNP cord-015369-72cjogxz 6694 10 4 4 CD cord-015369-72cjogxz 6694 11 ) ) -RRB- cord-015369-72cjogxz 6694 12 trat trat NNP cord-015369-72cjogxz 6694 13 i -PRON- PRP cord-015369-72cjogxz 6694 14 m be VBP cord-015369-72cjogxz 6694 15 Verlauf Verlauf NNP cord-015369-72cjogxz 6694 16 eine eine NNP cord-015369-72cjogxz 6694 17 Anastomoseninsuffizienz Anastomoseninsuffizienz NNP cord-015369-72cjogxz 6694 18 auf auf NNP cord-015369-72cjogxz 6694 19 ( ( -LRB- cord-015369-72cjogxz 6694 20 100 100 CD cord-015369-72cjogxz 6694 21 % % NN cord-015369-72cjogxz 6694 22 ) ) -RRB- cord-015369-72cjogxz 6694 23 . . . cord-015369-72cjogxz 6695 1 Die die VB cord-015369-72cjogxz 6695 2 Rate rate NN cord-015369-72cjogxz 6695 3 der der NNP cord-015369-72cjogxz 6695 4 Wundheilungsstörungen Wundheilungsstörungen NNP cord-015369-72cjogxz 6695 5 betrug betrug NNP cord-015369-72cjogxz 6695 6 Die Die NNP cord-015369-72cjogxz 6695 7 Peritonitis Peritonitis NNP cord-015369-72cjogxz 6695 8 nach nach NN cord-015369-72cjogxz 6695 9 GI GI NNP cord-015369-72cjogxz 6695 10 - - HYPH cord-015369-72cjogxz 6695 11 Perforation perforation NN cord-015369-72cjogxz 6695 12 infolge infolge XX cord-015369-72cjogxz 6695 13 einer einer NNP cord-015369-72cjogxz 6695 14 Bevacizumab Bevacizumab NNP cord-015369-72cjogxz 6695 15 - - HYPH cord-015369-72cjogxz 6695 16 Therapie Therapie NNP cord-015369-72cjogxz 6695 17 stellt stellt NNP cord-015369-72cjogxz 6695 18 eine eine NNP cord-015369-72cjogxz 6695 19 seltene seltene NNP cord-015369-72cjogxz 6695 20 Akassoziierte Akassoziierte NNP cord-015369-72cjogxz 6695 21 , , , cord-015369-72cjogxz 6695 22 aber aber NNP cord-015369-72cjogxz 6695 23 ernstzunehmende ernstzunehmende NNP cord-015369-72cjogxz 6695 24 , , , cord-015369-72cjogxz 6695 25 da da NNP cord-015369-72cjogxz 6695 26 lebensbedrohliche lebensbedrohliche NNP cord-015369-72cjogxz 6695 27 Komplikation Komplikation NNP cord-015369-72cjogxz 6695 28 dar dar NNP cord-015369-72cjogxz 6695 29 . . . cord-015369-72cjogxz 6696 1 Die die VBP cord-015369-72cjogxz 6696 2 i -PRON- PRP cord-015369-72cjogxz 6696 3 m be VBP cord-015369-72cjogxz 6696 4 Zusammenhang Zusammenhang NNP cord-015369-72cjogxz 6696 5 mit mit NNP cord-015369-72cjogxz 6696 6 der der NNP cord-015369-72cjogxz 6696 7 Neoangiogeneseinhibition Neoangiogeneseinhibition NNP cord-015369-72cjogxz 6696 8 gestörte gestörte NNS cord-015369-72cjogxz 6696 9 Wundheilung Wundheilung NNP cord-015369-72cjogxz 6696 10 bedingt bedingt NNP cord-015369-72cjogxz 6697 1 Abweichungen Abweichungen NNP cord-015369-72cjogxz 6697 2 i -PRON- PRP cord-015369-72cjogxz 6697 3 m be VBP cord-015369-72cjogxz 6697 4 Management Management NNP cord-015369-72cjogxz 6697 5 GI GI NNP cord-015369-72cjogxz 6697 6 - - HYPH cord-015369-72cjogxz 6697 7 Perforationsereignisse Perforationsereignisse NNP cord-015369-72cjogxz 6698 1 i -PRON- PRP cord-015369-72cjogxz 6698 2 m be VBP cord-015369-72cjogxz 6699 1 Vergleich Vergleich NNP cord-015369-72cjogxz 6699 2 zur zur NNP cord-015369-72cjogxz 6699 3 etablierten etablierten NNP cord-015369-72cjogxz 6700 1 chirurgischen chirurgischen NNP cord-015369-72cjogxz 6700 2 Standardversorgung Standardversorgung NNP cord-015369-72cjogxz 6700 3 Klinik Klinik NNP cord-015369-72cjogxz 6700 4 für für IN cord-015369-72cjogxz 6700 5 Viszeral- Viszeral- NNP cord-015369-72cjogxz 6700 6 , , , cord-015369-72cjogxz 6700 7 Transplantations Transplantations NNP cord-015369-72cjogxz 6700 8 - - HYPH cord-015369-72cjogxz 6700 9 und und NNP cord-015369-72cjogxz 6700 10 Thoraxchirurgie Thoraxchirurgie NNP cord-015369-72cjogxz 6700 11 Das Das NNP cord-015369-72cjogxz 6700 12 amelanotische amelanotische NN cord-015369-72cjogxz 6700 13 Melanom Melanom NNP cord-015369-72cjogxz 6700 14 des des NNP cord-015369-72cjogxz 6700 15 Rektums Rektums NNP cord-015369-72cjogxz 6700 16 ( ( -LRB- cord-015369-72cjogxz 6700 17 AMR AMR NNP cord-015369-72cjogxz 6700 18 ) ) -RRB- cord-015369-72cjogxz 6701 1 ist ist NNP cord-015369-72cjogxz 6701 2 eine eine NNP cord-015369-72cjogxz 6701 3 seltene seltene NNP cord-015369-72cjogxz 6701 4 Erkrankung Erkrankung NNP cord-015369-72cjogxz 6701 5 , , , cord-015369-72cjogxz 6701 6 dessen dessen NNP cord-015369-72cjogxz 6701 7 chirurgische chirurgische NNP cord-015369-72cjogxz 6701 8 Therapie Therapie NNP cord-015369-72cjogxz 6701 9 derzeit derzeit NNP cord-015369-72cjogxz 6701 10 kontrovers kontrovers NNP cord-015369-72cjogxz 6701 11 diskutiert diskutiert NNP cord-015369-72cjogxz 6701 12 ist ist NNP cord-015369-72cjogxz 6701 13 . . . cord-015369-72cjogxz 6702 1 Die die VB cord-015369-72cjogxz 6702 2 transrektale transrektale NN cord-015369-72cjogxz 6702 3 Ultraschalldiagnostik Ultraschalldiagnostik NNP cord-015369-72cjogxz 6702 4 ( ( -LRB- cord-015369-72cjogxz 6702 5 EUS eus NN cord-015369-72cjogxz 6702 6 ) ) -RRB- cord-015369-72cjogxz 6703 1 besitzt besitzt NNP cord-015369-72cjogxz 6703 2 in in IN cord-015369-72cjogxz 6703 3 der der NNP cord-015369-72cjogxz 6703 4 Diagnostik Diagnostik NNP cord-015369-72cjogxz 6703 5 und und NNP cord-015369-72cjogxz 6704 1 Nachsorge Nachsorge NNP cord-015369-72cjogxz 6704 2 eine eine NNP cord-015369-72cjogxz 6705 1 entscheidende entscheidende NNP cord-015369-72cjogxz 6705 2 Bedeutung Bedeutung NNP cord-015369-72cjogxz 6705 3 der der NNP cord-015369-72cjogxz 6706 1 Literatur Literatur NNP cord-015369-72cjogxz 6706 2 wurden wurden VBD cord-015369-72cjogxz 6706 3 innerhalb innerhalb NNP cord-015369-72cjogxz 6706 4 von von NNP cord-015369-72cjogxz 6706 5 30 30 CD cord-015369-72cjogxz 6706 6 Jahren Jahren NNP cord-015369-72cjogxz 6706 7 Anhand Anhand NNP cord-015369-72cjogxz 6706 8 von von NNP cord-015369-72cjogxz 6706 9 2 2 CD cord-015369-72cjogxz 6706 10 repräsentativen repräsentativen NNP cord-015369-72cjogxz 6706 11 Fallberichten Fallberichten NNP cord-015369-72cjogxz 6706 12 für für IN cord-015369-72cjogxz 6706 13 AMR AMR NNP cord-015369-72cjogxz 6707 1 i -PRON- PRP cord-015369-72cjogxz 6707 2 m be VBP cord-015369-72cjogxz 6707 3 Rahmen Rahmen NNP cord-015369-72cjogxz 6708 1 einer einer NNP cord-015369-72cjogxz 6708 2 klinischen klinischen NNP cord-015369-72cjogxz 6708 3 Bicenterbeobachtungsstudie Bicenterbeobachtungsstudie NNP cord-015369-72cjogxz 6708 4 zur zur NNP cord-015369-72cjogxz 6708 5 Qualitätssicherung Qualitätssicherung NNP cord-015369-72cjogxz 6708 6 in in IN cord-015369-72cjogxz 6708 7 der der NNP cord-015369-72cjogxz 6708 8 Rektumchirurgie Rektumchirurgie NNP cord-015369-72cjogxz 6708 9 wird wird NNP cord-015369-72cjogxz 6708 10 über über NNP cord-015369-72cjogxz 6708 11 das das NNP cord-015369-72cjogxz 6708 12 therapeutische therapeutische IN cord-015369-72cjogxz 6708 13 Spektrum Spektrum NNP cord-015369-72cjogxz 6709 1 dieser dieser NNP cord-015369-72cjogxz 6709 2 seltenen seltenen NNP cord-015369-72cjogxz 6709 3 Befunde Befunde NNP cord-015369-72cjogxz 6709 4 und und IN cord-015369-72cjogxz 6709 5 Maßnahmen Maßnahmen NNP cord-015369-72cjogxz 6709 6 in in IN cord-015369-72cjogxz 6709 7 Abhängigkeit Abhängigkeit NNP cord-015369-72cjogxz 6709 8 vom vom NN cord-015369-72cjogxz 6709 9 individuellen individuellen NNP cord-015369-72cjogxz 6709 10 Verlauf Verlauf NNP cord-015369-72cjogxz 6709 11 berichtet berichtet NNP cord-015369-72cjogxz 6710 1 Die die VB cord-015369-72cjogxz 6710 2 Patientin Patientin NNP cord-015369-72cjogxz 6710 3 verstarb verstarb NN cord-015369-72cjogxz 6710 4 jedoch jedoch NNP cord-015369-72cjogxz 6710 5 36 36 CD cord-015369-72cjogxz 6710 6 Monate Monate NNP cord-015369-72cjogxz 6710 7 nach nach NNP cord-015369-72cjogxz 6710 8 der der NNP cord-015369-72cjogxz 6710 9 Erstdiagnose Erstdiagnose NNP cord-015369-72cjogxz 6710 10 . . . cord-015369-72cjogxz 6711 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6711 2 . . . cord-015369-72cjogxz 6712 1 Die die VB cord-015369-72cjogxz 6712 2 Prognose Prognose NNP cord-015369-72cjogxz 6712 3 des des NNP cord-015369-72cjogxz 6713 1 AMR AMR NNP cord-015369-72cjogxz 6713 2 ist ist NNP cord-015369-72cjogxz 6713 3 unabhängig unabhängig NNS cord-015369-72cjogxz 6713 4 von von NNP cord-015369-72cjogxz 6713 5 der der NNP cord-015369-72cjogxz 6713 6 chirurgischen chirurgischen NNP cord-015369-72cjogxz 6713 7 Therapie Therapie NNP cord-015369-72cjogxz 6713 8 schlecht schlecht NNP cord-015369-72cjogxz 6713 9 . . . cord-015369-72cjogxz 6714 1 Die die UH cord-015369-72cjogxz 6714 2 lokale lokale NNP cord-015369-72cjogxz 6714 3 Tumorresektion Tumorresektion NNP cord-015369-72cjogxz 6714 4 mit mit NNP cord-015369-72cjogxz 6714 5 einem einem NNP cord-015369-72cjogxz 6714 6 Sicherheitsabstand Sicherheitsabstand NNP cord-015369-72cjogxz 6714 7 von von NNP cord-015369-72cjogxz 6715 1 1 1 CD cord-015369-72cjogxz 6715 2 cm cm NN cord-015369-72cjogxz 6715 3 ist ist NNP cord-015369-72cjogxz 6715 4 das das NNP cord-015369-72cjogxz 6715 5 primäre primäre NNP cord-015369-72cjogxz 6715 6 Verfahren Verfahren NNP cord-015369-72cjogxz 6715 7 der der NNP cord-015369-72cjogxz 6715 8 Wahl Wahl NNP cord-015369-72cjogxz 6715 9 , , , cord-015369-72cjogxz 6715 10 die die VB cord-015369-72cjogxz 6715 11 APR APR NNP cord-015369-72cjogxz 6715 12 hingegen hingegen NNP cord-015369-72cjogxz 6715 13 sollte sollte NNP cord-015369-72cjogxz 6715 14 den den NNP cord-015369-72cjogxz 6716 1 verbleibenden verbleibenden NNP cord-015369-72cjogxz 6716 2 Fällen Fällen NNP cord-015369-72cjogxz 6716 3 vorbehalten vorbehalten NN cord-015369-72cjogxz 6716 4 bleiben bleiben VBP cord-015369-72cjogxz 6716 5 Severe severe JJ cord-015369-72cjogxz 6717 1 facial facial JJ cord-015369-72cjogxz 6717 2 hyperhidosis hyperhidosis NNP cord-015369-72cjogxz 6717 3 ( ( -LRB- cord-015369-72cjogxz 6717 4 FH FH NNP cord-015369-72cjogxz 6717 5 ) ) -RRB- cord-015369-72cjogxz 6717 6 bothers bother VBZ cord-015369-72cjogxz 6717 7 patients patient NNS cord-015369-72cjogxz 6717 8 ' ' `` cord-015369-72cjogxz 6717 9 every every DT cord-015369-72cjogxz 6717 10 day day NN cord-015369-72cjogxz 6717 11 life life NN cord-015369-72cjogxz 6717 12 and and CC cord-015369-72cjogxz 6717 13 leads lead VBZ cord-015369-72cjogxz 6717 14 to to IN cord-015369-72cjogxz 6717 15 human human JJ cord-015369-72cjogxz 6717 16 withdrawal withdrawal NN cord-015369-72cjogxz 6717 17 and and CC cord-015369-72cjogxz 6717 18 social social JJ cord-015369-72cjogxz 6717 19 phobia phobia NN cord-015369-72cjogxz 6717 20 . . . cord-015369-72cjogxz 6718 1 The the DT cord-015369-72cjogxz 6718 2 aim aim NN cord-015369-72cjogxz 6718 3 of of IN cord-015369-72cjogxz 6718 4 the the DT cord-015369-72cjogxz 6718 5 study study NN cord-015369-72cjogxz 6718 6 was be VBD cord-015369-72cjogxz 6718 7 to to TO cord-015369-72cjogxz 6718 8 assess assess VB cord-015369-72cjogxz 6718 9 pre pre JJ cord-015369-72cjogxz 6718 10 - - JJ cord-015369-72cjogxz 6718 11 and and CC cord-015369-72cjogxz 6718 12 postoperative postoperative JJ cord-015369-72cjogxz 6718 13 Quality quality NN cord-015369-72cjogxz 6718 14 of of IN cord-015369-72cjogxz 6718 15 life life NN cord-015369-72cjogxz 6718 16 ( ( -LRB- cord-015369-72cjogxz 6718 17 Qol Qol NNP cord-015369-72cjogxz 6718 18 ) ) -RRB- cord-015369-72cjogxz 6718 19 using use VBG cord-015369-72cjogxz 6718 20 a a DT cord-015369-72cjogxz 6718 21 disease disease NN cord-015369-72cjogxz 6718 22 - - HYPH cord-015369-72cjogxz 6718 23 specific specific JJ cord-015369-72cjogxz 6718 24 Qol Qol NNP cord-015369-72cjogxz 6718 25 questionnaire questionnaire NN cord-015369-72cjogxz 6718 26 after after IN cord-015369-72cjogxz 6718 27 limited limited JJ cord-015369-72cjogxz 6718 28 endoscopic endoscopic JJ cord-015369-72cjogxz 6718 29 thoracic thoracic JJ cord-015369-72cjogxz 6718 30 sympathetic sympathetic JJ cord-015369-72cjogxz 6718 31 block block NN cord-015369-72cjogxz 6718 32 at at IN cord-015369-72cjogxz 6718 33 T3 T3 NNP cord-015369-72cjogxz 6718 34 ( ( -LRB- cord-015369-72cjogxz 6718 35 ESB3 ESB3 NNP cord-015369-72cjogxz 6718 36 ) ) -RRB- cord-015369-72cjogxz 6718 37 for for IN cord-015369-72cjogxz 6718 38 FH FH NNP cord-015369-72cjogxz 6718 39 . . . cord-015369-72cjogxz 6719 1 Methods method NNS cord-015369-72cjogxz 6719 2 . . . cord-015369-72cjogxz 6720 1 Fifty fifty CD cord-015369-72cjogxz 6720 2 patients patient NNS cord-015369-72cjogxz 6720 3 underwent undergo VBD cord-015369-72cjogxz 6720 4 100 100 CD cord-015369-72cjogxz 6720 5 ESB3 ESB3 NNP cord-015369-72cjogxz 6720 6 procedures procedure NNS cord-015369-72cjogxz 6720 7 in in IN cord-015369-72cjogxz 6720 8 a a DT cord-015369-72cjogxz 6720 9 prospective prospective JJ cord-015369-72cjogxz 6720 10 study study NN cord-015369-72cjogxz 6720 11 between between IN cord-015369-72cjogxz 6720 12 2002 2002 CD cord-015369-72cjogxz 6720 13 and and CC cord-015369-72cjogxz 6720 14 2009 2009 CD cord-015369-72cjogxz 6720 15 at at IN cord-015369-72cjogxz 6720 16 a a DT cord-015369-72cjogxz 6720 17 mean mean NN cord-015369-72cjogxz 6720 18 follow follow VB cord-015369-72cjogxz 6720 19 up up IN cord-015369-72cjogxz 6720 20 of of IN cord-015369-72cjogxz 6720 21 57.8 57.8 CD cord-015369-72cjogxz 6720 22 AE AE NNP cord-015369-72cjogxz 6720 23 22.0 22.0 CD cord-015369-72cjogxz 6720 24 months month NNS cord-015369-72cjogxz 6720 25 . . . cord-015369-72cjogxz 6721 1 A a DT cord-015369-72cjogxz 6721 2 validated validate VBN cord-015369-72cjogxz 6721 3 disease disease NN cord-015369-72cjogxz 6721 4 - - HYPH cord-015369-72cjogxz 6721 5 specific specific JJ cord-015369-72cjogxz 6721 6 Qol Qol NNP cord-015369-72cjogxz 6721 7 questionnaire questionnaire NN cord-015369-72cjogxz 6721 8 by by IN cord-015369-72cjogxz 6721 9 Milanez Milanez NNP cord-015369-72cjogxz 6721 10 de de NNP cord-015369-72cjogxz 6721 11 Campos Campos NNP cord-015369-72cjogxz 6721 12 ( ( -LRB- cord-015369-72cjogxz 6721 13 1 1 CD cord-015369-72cjogxz 6721 14 - - SYM cord-015369-72cjogxz 6721 15 5 5 CD cord-015369-72cjogxz 6721 16 ) ) -RRB- cord-015369-72cjogxz 6721 17 and and CC cord-015369-72cjogxz 6721 18 a a DT cord-015369-72cjogxz 6721 19 visual visual JJ cord-015369-72cjogxz 6721 20 analogue analogue NN cord-015369-72cjogxz 6721 21 scale scale NN cord-015369-72cjogxz 6721 22 ( ( -LRB- cord-015369-72cjogxz 6721 23 VAS vas NN cord-015369-72cjogxz 6721 24 ; ; : cord-015369-72cjogxz 6721 25 1 1 CD cord-015369-72cjogxz 6721 26 - - SYM cord-015369-72cjogxz 6721 27 10 10 CD cord-015369-72cjogxz 6721 28 ) ) -RRB- cord-015369-72cjogxz 6721 29 concerning concern VBG cord-015369-72cjogxz 6721 30 the the DT cord-015369-72cjogxz 6721 31 extent extent NN cord-015369-72cjogxz 6721 32 of of IN cord-015369-72cjogxz 6721 33 FH FH NNP cord-015369-72cjogxz 6721 34 were be VBD cord-015369-72cjogxz 6721 35 evaluated evaluate VBN cord-015369-72cjogxz 6721 36 by by IN cord-015369-72cjogxz 6721 37 annual annual JJ cord-015369-72cjogxz 6721 38 telephone telephone NN cord-015369-72cjogxz 6721 39 calls call NNS cord-015369-72cjogxz 6721 40 ( ( -LRB- cord-015369-72cjogxz 6721 41 1 1 CD cord-015369-72cjogxz 6721 42 : : : cord-015369-72cjogxz 6721 43 no no DT cord-015369-72cjogxz 6721 44 symptoms symptom NNS cord-015369-72cjogxz 6721 45 ; ; : cord-015369-72cjogxz 6722 1 5 5 CD cord-015369-72cjogxz 6722 2 or or CC cord-015369-72cjogxz 6722 3 10 10 CD cord-015369-72cjogxz 6722 4 : : : cord-015369-72cjogxz 6722 5 maximal maximal JJ cord-015369-72cjogxz 6722 6 symptoms symptom NNS cord-015369-72cjogxz 6722 7 ) ) -RRB- cord-015369-72cjogxz 6722 8 . . . cord-015369-72cjogxz 6723 1 Results result NNS cord-015369-72cjogxz 6723 2 . . . cord-015369-72cjogxz 6724 1 VAS VAS NNP cord-015369-72cjogxz 6724 2 scores score NNS cord-015369-72cjogxz 6724 3 decreased decrease VBD cord-015369-72cjogxz 6724 4 from from IN cord-015369-72cjogxz 6724 5 9.1 9.1 CD cord-015369-72cjogxz 6724 6 AE AE NNP cord-015369-72cjogxz 6724 7 1.5 1.5 CD cord-015369-72cjogxz 6724 8 preoperatively preoperatively NN cord-015369-72cjogxz 6724 9 to to IN cord-015369-72cjogxz 6724 10 1.9 1.9 CD cord-015369-72cjogxz 6724 11 AE AE NNP cord-015369-72cjogxz 6724 12 0.6 0.6 CD cord-015369-72cjogxz 6724 13 postoperatively postoperatively RB cord-015369-72cjogxz 6724 14 and and CC cord-015369-72cjogxz 6724 15 to to IN cord-015369-72cjogxz 6724 16 2.1 2.1 CD cord-015369-72cjogxz 6724 17 AE AE NNP cord-015369-72cjogxz 6724 18 0.4 0.4 CD cord-015369-72cjogxz 6724 19 at at IN cord-015369-72cjogxz 6724 20 long long JJ cord-015369-72cjogxz 6724 21 term term NN cord-015369-72cjogxz 6724 22 follow follow VB cord-015369-72cjogxz 6724 23 up up RP cord-015369-72cjogxz 6724 24 ( ( -LRB- cord-015369-72cjogxz 6724 25 p p NN cord-015369-72cjogxz 6724 26 < < XX cord-015369-72cjogxz 6724 27 0.001 0.001 CD cord-015369-72cjogxz 6724 28 ) ) -RRB- cord-015369-72cjogxz 6724 29 . . . cord-015369-72cjogxz 6725 1 46 46 CD cord-015369-72cjogxz 6725 2 patients patient NNS cord-015369-72cjogxz 6725 3 ( ( -LRB- cord-015369-72cjogxz 6725 4 92 92 CD cord-015369-72cjogxz 6725 5 % % NN cord-015369-72cjogxz 6725 6 ) ) -RRB- cord-015369-72cjogxz 6725 7 were be VBD cord-015369-72cjogxz 6725 8 completely completely RB cord-015369-72cjogxz 6725 9 or or CC cord-015369-72cjogxz 6725 10 almost almost RB cord-015369-72cjogxz 6725 11 dry dry JJ cord-015369-72cjogxz 6725 12 postoperatively postoperatively RB cord-015369-72cjogxz 6725 13 . . . cord-015369-72cjogxz 6726 1 Side side JJ cord-015369-72cjogxz 6726 2 effects effect NNS cord-015369-72cjogxz 6726 3 , , , cord-015369-72cjogxz 6726 4 such such JJ cord-015369-72cjogxz 6726 5 as as IN cord-015369-72cjogxz 6726 6 compensatory compensatory JJ cord-015369-72cjogxz 6726 7 sweating sweating NN cord-015369-72cjogxz 6726 8 ( ( -LRB- cord-015369-72cjogxz 6726 9 CS CS NNP cord-015369-72cjogxz 6726 10 ) ) -RRB- cord-015369-72cjogxz 6726 11 and and CC cord-015369-72cjogxz 6726 12 gustatory gustatory JJ cord-015369-72cjogxz 6726 13 sweating sweating NN cord-015369-72cjogxz 6726 14 were be VBD cord-015369-72cjogxz 6726 15 each each DT cord-015369-72cjogxz 6726 16 AE AE NNP cord-015369-72cjogxz 6726 17 14.1 14.1 CD cord-015369-72cjogxz 6726 18 at at IN cord-015369-72cjogxz 6726 19 a a DT cord-015369-72cjogxz 6726 20 5 5 CD cord-015369-72cjogxz 6726 21 year year NN cord-015369-72cjogxz 6726 22 follow follow VB cord-015369-72cjogxz 6726 23 up up RP cord-015369-72cjogxz 6726 24 ( ( -LRB- cord-015369-72cjogxz 6726 25 p p NN cord-015369-72cjogxz 6726 26 < < XX cord-015369-72cjogxz 6726 27 0.01 0.01 CD cord-015369-72cjogxz 6726 28 ) ) -RRB- cord-015369-72cjogxz 6727 1 Endoscopic endoscopic JJ cord-015369-72cjogxz 6727 2 sympathetic sympathetic JJ cord-015369-72cjogxz 6727 3 block block NN cord-015369-72cjogxz 6727 4 at at IN cord-015369-72cjogxz 6727 5 T3 T3 NNP cord-015369-72cjogxz 6727 6 reduces reduce VBZ cord-015369-72cjogxz 6727 7 FH FH NNP cord-015369-72cjogxz 6727 8 efficiently efficiently RB cord-015369-72cjogxz 6727 9 and and CC cord-015369-72cjogxz 6727 10 improves improve VBZ cord-015369-72cjogxz 6727 11 Qol Qol NNP cord-015369-72cjogxz 6727 12 . . . cord-015369-72cjogxz 6728 1 CS CS NNP cord-015369-72cjogxz 6728 2 impairs impair VBZ cord-015369-72cjogxz 6728 3 Qol Qol NNP cord-015369-72cjogxz 6728 4 substantially substantially RB cord-015369-72cjogxz 6728 5 emphasizing emphasize VBG cord-015369-72cjogxz 6728 6 the the DT cord-015369-72cjogxz 6728 7 importance importance NN cord-015369-72cjogxz 6728 8 of of IN cord-015369-72cjogxz 6728 9 clip clip NN cord-015369-72cjogxz 6728 10 removal removal NN cord-015369-72cjogxz 6729 1 induce induce VB cord-015369-72cjogxz 6729 2 clip clip NN cord-015369-72cjogxz 6729 3 removal removal NN cord-015369-72cjogxz 6729 4 as as IN cord-015369-72cjogxz 6729 5 final final JJ cord-015369-72cjogxz 6729 6 retreat retreat NN cord-015369-72cjogxz 6729 7 strategy strategy NN cord-015369-72cjogxz 6730 1 -cava -cava LS cord-015369-72cjogxz 6730 2 - - : cord-015369-72cjogxz 6730 3 inferior(VCI)-assoziierte inferior(VCI)-assoziierte NNP cord-015369-72cjogxz 6730 4 Tumorläsionen Tumorläsionen NNP cord-015369-72cjogxz 6730 5 stellen stellen XX cord-015369-72cjogxz 6731 1 eine eine NNP cord-015369-72cjogxz 6731 2 außerordentliche außerordentliche NNP cord-015369-72cjogxz 6732 1 Herausforderung Herausforderung NNP cord-015369-72cjogxz 6733 1 i -PRON- PRP cord-015369-72cjogxz 6733 2 m be VBP cord-015369-72cjogxz 6733 3 interdisziplinären interdisziplinären NNP cord-015369-72cjogxz 6734 1 Behandlungskonzept Behandlungskonzept NNP cord-015369-72cjogxz 6734 2 von von NNP cord-015369-72cjogxz 6734 3 Viszeral Viszeral NNP cord-015369-72cjogxz 6734 4 Gefäßwandinfiltration Gefäßwandinfiltration NNP cord-015369-72cjogxz 6734 5 und und IN cord-015369-72cjogxz 6734 6 ( ( -LRB- cord-015369-72cjogxz 6734 7 iii iii NN cord-015369-72cjogxz 6734 8 ) ) -RRB- cord-015369-72cjogxz 6734 9 intraluminalen intraluminalen NNP cord-015369-72cjogxz 6734 10 Tumorzapfen Tumorzapfen NNP cord-015369-72cjogxz 6734 11 mit mit NNP cord-015369-72cjogxz 6734 12 Alteration Alteration NNP cord-015369-72cjogxz 6734 13 des des NNP cord-015369-72cjogxz 6735 1 Blutstroms Blutstroms NNP cord-015369-72cjogxz 6735 2 i -PRON- PRP cord-015369-72cjogxz 6735 3 m be VBP cord-015369-72cjogxz 6735 4 gefäßchirurgischen gefäßchirurgischen NN cord-015369-72cjogxz 6735 5 Patientenklientel Patientenklientel NNP cord-015369-72cjogxz 6735 6 eines eine NNS cord-015369-72cjogxz 6736 1 chirurgischen chirurgischen NNP cord-015369-72cjogxz 6736 2 Zentrums Zentrums NNP cord-015369-72cjogxz 6736 3 prospektiv prospektiv NNP cord-015369-72cjogxz 6736 4 erfasst erfasst NNP cord-015369-72cjogxz 6736 5 und und RB cord-015369-72cjogxz 6737 1 retrospektiv retrospektiv NNP cord-015369-72cjogxz 6737 2 ausgewertet ausgewertet NNP cord-015369-72cjogxz 6737 3 . . . cord-015369-72cjogxz 6738 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6738 2 . . . cord-015369-72cjogxz 6739 1 Es Es NNP cord-015369-72cjogxz 6739 2 wurden wurden NNP cord-015369-72cjogxz 6739 3 insgesamt insgesamt NNP cord-015369-72cjogxz 6739 4 14 14 CD cord-015369-72cjogxz 6739 5 Patienten Patienten NNP cord-015369-72cjogxz 6739 6 operativ operativ NN cord-015369-72cjogxz 6739 7 behandelt behandelt NNP cord-015369-72cjogxz 6739 8 : : : cord-015369-72cjogxz 6739 9 6 6 CD cord-015369-72cjogxz 6739 10 Leiomyosarkome Leiomyosarkome NNP cord-015369-72cjogxz 6739 11 der der NN cord-015369-72cjogxz 6739 12 VCI VCI NNP cord-015369-72cjogxz 6739 13 ( ( -LRB- cord-015369-72cjogxz 6739 14 42,8 42,8 CD cord-015369-72cjogxz 6739 15 % % NN cord-015369-72cjogxz 6739 16 ) ) -RRB- cord-015369-72cjogxz 6739 17 , , , cord-015369-72cjogxz 6739 18 2 2 CD cord-015369-72cjogxz 6739 19 retroperitoneale retroperitoneale NN cord-015369-72cjogxz 6740 1 Tumore Tumore NNP cord-015369-72cjogxz 6741 1 ( ( -LRB- cord-015369-72cjogxz 6741 2 Seminommetastase Seminommetastase NNP cord-015369-72cjogxz 6741 3 , , , cord-015369-72cjogxz 6741 4 Paraganglion Paraganglion NNP cord-015369-72cjogxz 6741 5 ; ; : cord-015369-72cjogxz 6741 6 14,3 14,3 CD cord-015369-72cjogxz 6741 7 % % NN cord-015369-72cjogxz 6741 8 ) ) -RRB- cord-015369-72cjogxz 6741 9 als als NN cord-015369-72cjogxz 6742 1 auch auch NNP cord-015369-72cjogxz 6742 2 von von NNP cord-015369-72cjogxz 6742 3 außen außen NNP cord-015369-72cjogxz 6742 4 infiltrierende infiltrierende NNP cord-015369-72cjogxz 6742 5 Tumore Tumore NNP cord-015369-72cjogxz 6743 1 und und NNP cord-015369-72cjogxz 6744 1 1 1 CD cord-015369-72cjogxz 6744 2 cholangiozelluläres cholangiozelluläres NNP cord-015369-72cjogxz 6745 1 Karzinom Karzinom NNP cord-015369-72cjogxz 6745 2 mit mit NNP cord-015369-72cjogxz 6745 3 VCI VCI NNP cord-015369-72cjogxz 6745 4 - - HYPH cord-015369-72cjogxz 6745 5 Adhäsion Adhäsion NNP cord-015369-72cjogxz 6745 6 ( ( -LRB- cord-015369-72cjogxz 6745 7 7,2 7,2 CD cord-015369-72cjogxz 6745 8 % % NN cord-015369-72cjogxz 6745 9 ) ) -RRB- cord-015369-72cjogxz 6746 1 und und NNP cord-015369-72cjogxz 6747 1 5 5 LS cord-015369-72cjogxz 6747 2 Tumorzapfen Tumorzapfen NNP cord-015369-72cjogxz 6747 3 ( ( -LRB- cord-015369-72cjogxz 6747 4 35,7 35,7 CD cord-015369-72cjogxz 6747 5 % % NN cord-015369-72cjogxz 6747 6 ; ; : cord-015369-72cjogxz 6747 7 4 4 CD cord-015369-72cjogxz 6747 8 Nierenzell-/1 Nierenzell-/1 NNP cord-015369-72cjogxz 6747 9 Nebennierenrindenkarzinom Nebennierenrindenkarzinom NNPS cord-015369-72cjogxz 6747 10 ) ) -RRB- cord-015369-72cjogxz 6747 11 . . . cord-015369-72cjogxz 6748 1 Die Die NNP cord-015369-72cjogxz 6748 2 Tumorresektionsrate Tumorresektionsrate NNP cord-015369-72cjogxz 6748 3 betrug betrug NNP cord-015369-72cjogxz 6748 4 100 100 CD cord-015369-72cjogxz 6748 5 % % NN cord-015369-72cjogxz 6748 6 . . . cord-015369-72cjogxz 6749 1 Op Op NNP cord-015369-72cjogxz 6749 2 - - HYPH cord-015369-72cjogxz 6749 3 technisch technisch NNP cord-015369-72cjogxz 6749 4 wurde wurde NNP cord-015369-72cjogxz 6749 5 die die VB cord-015369-72cjogxz 6750 1 VCI VCI NNP cord-015369-72cjogxz 6750 2 entweder entweder NNP cord-015369-72cjogxz 6750 3 ü ü NN cord-015369-72cjogxz 6750 4 ber ber NNP cord-015369-72cjogxz 6750 5 die die VB cord-015369-72cjogxz 6751 1 tumorbefallene tumorbefallene NNP cord-015369-72cjogxz 6751 2 Strecke Strecke NNP cord-015369-72cjogxz 6751 3 komplett komplett NNP cord-015369-72cjogxz 6752 1 durch durch NNP cord-015369-72cjogxz 6752 2 eine eine NNP cord-015369-72cjogxz 6752 3 Gefäßprothese Gefäßprothese NNP cord-015369-72cjogxz 6752 4 ersetzt ersetzt VBD cord-015369-72cjogxz 6752 5 , , , cord-015369-72cjogxz 6752 6 eine eine FW cord-015369-72cjogxz 6752 7 partielle partielle NNP cord-015369-72cjogxz 6752 8 Wandresektion Wandresektion NNP cord-015369-72cjogxz 6752 9 mit mit NNP cord-015369-72cjogxz 6752 10 anschließender anschließender NNP cord-015369-72cjogxz 6752 11 Patchplastik Patchplastik NNP cord-015369-72cjogxz 6752 12 , , , cord-015369-72cjogxz 6752 13 die die VB cord-015369-72cjogxz 6752 14 tangentielle tangentielle NNP cord-015369-72cjogxz 6753 1 Resektion Resektion NNP cord-015369-72cjogxz 6753 2 mit mit JJ cord-015369-72cjogxz 6753 3 primärer primärer NN cord-015369-72cjogxz 6753 4 Naht Naht NNP cord-015369-72cjogxz 6754 1 oder oder NNP cord-015369-72cjogxz 6754 2 die die NNP cord-015369-72cjogxz 6755 1 Ausschälung Ausschälung NNP cord-015369-72cjogxz 6755 2 des des NNP cord-015369-72cjogxz 6755 3 Cavathrombus Cavathrombus NNP cord-015369-72cjogxz 6755 4 nach nach NNP cord-015369-72cjogxz 6755 5 Cavotomie Cavotomie NNP cord-015369-72cjogxz 6755 6 vorgenommen vorgenomman NNS cord-015369-72cjogxz 6755 7 . . . cord-015369-72cjogxz 6756 1 Die die VB cord-015369-72cjogxz 6756 2 Tumorzapfen Tumorzapfen NNP cord-015369-72cjogxz 6756 3 wurden wurden XX cord-015369-72cjogxz 6757 1 mit mit NNP cord-015369-72cjogxz 6757 2 / / SYM cord-015369-72cjogxz 6757 3 ohne ohne NNP cord-015369-72cjogxz 6757 4 VCI VCI NNP cord-015369-72cjogxz 6757 5 - - HYPH cord-015369-72cjogxz 6757 6 Resektion Resektion NNP cord-015369-72cjogxz 6757 7 erfolgreich erfolgreich NNS cord-015369-72cjogxz 6757 8 reseziert reseziert VBP cord-015369-72cjogxz 6757 9 Eine Eine NNP cord-015369-72cjogxz 6757 10 Operation Operation NNP cord-015369-72cjogxz 6758 1 VCI vci NN cord-015369-72cjogxz 6758 2 - - HYPH cord-015369-72cjogxz 6758 3 assoziierter assoziierter NN cord-015369-72cjogxz 6758 4 Tumore Tumore NNP cord-015369-72cjogxz 6758 5 ist ist VBP cord-015369-72cjogxz 6758 6 nur nur NNP cord-015369-72cjogxz 6758 7 bei bei NNP cord-015369-72cjogxz 6758 8 aussichtsreicher aussichtsreicher NNP cord-015369-72cjogxz 6759 1 R0-Resektion R0-Resektion NNP cord-015369-72cjogxz 6759 2 sinnvoll sinnvoll NNP cord-015369-72cjogxz 6760 1 316 316 CD cord-015369-72cjogxz 6760 2 patients patient NNS cord-015369-72cjogxz 6760 3 underwent undergo VBD cord-015369-72cjogxz 6760 4 19-or 19-or CD cord-015369-72cjogxz 6760 5 21-mm 21-mm CD cord-015369-72cjogxz 6760 6 mechanical mechanical JJ cord-015369-72cjogxz 6760 7 aortic aortic JJ cord-015369-72cjogxz 6760 8 valve valve NN cord-015369-72cjogxz 6760 9 replacement replacement NN cord-015369-72cjogxz 6760 10 , , , cord-015369-72cjogxz 6760 11 receiving receive VBG cord-015369-72cjogxz 6760 12 either either CC cord-015369-72cjogxz 6760 13 a a DT cord-015369-72cjogxz 6760 14 CarboMedics CarboMedics NNP cord-015369-72cjogxz 6760 15 Top Top NNP cord-015369-72cjogxz 6760 16 Hat Hat NNP cord-015369-72cjogxz 6760 17 valve valve NN cord-015369-72cjogxz 6760 18 ( ( -LRB- cord-015369-72cjogxz 6760 19 n n NN cord-015369-72cjogxz 6760 20 ¼ ¼ NNP cord-015369-72cjogxz 6760 21 56 56 CD cord-015369-72cjogxz 6760 22 ; ; : cord-015369-72cjogxz 6761 1 mean mean JJ cord-015369-72cjogxz 6761 2 age age NN cord-015369-72cjogxz 6761 3 , , , cord-015369-72cjogxz 6761 4 66 66 CD cord-015369-72cjogxz 6761 5 AE AE NNP cord-015369-72cjogxz 6761 6 14 14 CD cord-015369-72cjogxz 6761 7 years year NNS cord-015369-72cjogxz 6761 8 ) ) -RRB- cord-015369-72cjogxz 6761 9 or or CC cord-015369-72cjogxz 6761 10 a a DT cord-015369-72cjogxz 6761 11 standard standard JJ cord-015369-72cjogxz 6761 12 CarboMedics CarboMedics NNP cord-015369-72cjogxz 6761 13 one one NN cord-015369-72cjogxz 6761 14 ( ( -LRB- cord-015369-72cjogxz 6761 15 n n NN cord-015369-72cjogxz 6761 16 ¼ ¼ NNP cord-015369-72cjogxz 6761 17 260 260 CD cord-015369-72cjogxz 6761 18 ; ; : cord-015369-72cjogxz 6761 19 mean mean VB cord-015369-72cjogxz 6761 20 age age NN cord-015369-72cjogxz 6761 21 , , , cord-015369-72cjogxz 6761 22 60 60 CD cord-015369-72cjogxz 6761 23 AE AE NNP cord-015369-72cjogxz 6761 24 13 13 CD cord-015369-72cjogxz 6761 25 years year NNS cord-015369-72cjogxz 6761 26 ) ) -RRB- cord-015369-72cjogxz 6761 27 at at IN cord-015369-72cjogxz 6761 28 our -PRON- PRP$ cord-015369-72cjogxz 6761 29 institution institution NN cord-015369-72cjogxz 6761 30 . . . cord-015369-72cjogxz 6762 1 Median median JJ cord-015369-72cjogxz 6762 2 follow follow NN cord-015369-72cjogxz 6762 3 - - HYPH cord-015369-72cjogxz 6762 4 up up RP cord-015369-72cjogxz 6762 5 time time NN cord-015369-72cjogxz 6762 6 was be VBD cord-015369-72cjogxz 6762 7 83.5 83.5 CD cord-015369-72cjogxz 6762 8 months month NNS cord-015369-72cjogxz 6762 9 . . . cord-015369-72cjogxz 6763 1 We -PRON- PRP cord-015369-72cjogxz 6763 2 performed perform VBD cord-015369-72cjogxz 6763 3 echocardiographic echocardiographic JJ cord-015369-72cjogxz 6763 4 follow follow NN cord-015369-72cjogxz 6763 5 - - HYPH cord-015369-72cjogxz 6763 6 up up NN cord-015369-72cjogxz 6763 7 Austria Austria NNP cord-015369-72cjogxz 6764 1 Neben Neben NNP cord-015369-72cjogxz 6764 2 dem dem VBP cord-015369-72cjogxz 6764 3 angeborenen angeborenen NNP cord-015369-72cjogxz 6764 4 AV AV NNP cord-015369-72cjogxz 6764 5 - - HYPH cord-015369-72cjogxz 6764 6 Block Block NNP cord-015369-72cjogxz 6764 7 haben haben NN cord-015369-72cjogxz 6764 8 zunehmende zunehmende NNP cord-015369-72cjogxz 6764 9 Fortschritte Fortschritte NNP cord-015369-72cjogxz 6764 10 der der NNP cord-015369-72cjogxz 6764 11 Herzchirurgie Herzchirurgie NNP cord-015369-72cjogxz 6764 12 mit mit NNP cord-015369-72cjogxz 6764 13 Tendenz Tendenz NNP cord-015369-72cjogxz 6764 14 und und XX cord-015369-72cjogxz 6765 1 Notwendigkeit Notwendigkeit NNP cord-015369-72cjogxz 6765 2 , , , cord-015369-72cjogxz 6765 3 immer immer NNP cord-015369-72cjogxz 6765 4 komplexere komplexere NNP cord-015369-72cjogxz 6765 5 Operationen Operationen NNP cord-015369-72cjogxz 6765 6 zu zu NNP cord-015369-72cjogxz 6765 7 immer immer NNP cord-015369-72cjogxz 6765 8 frü frü NNP cord-015369-72cjogxz 6765 9 heren heren NNP cord-015369-72cjogxz 6765 10 Zeitpunkt Zeitpunkt NNP cord-015369-72cjogxz 6765 11 auszufü auszufü NNP cord-015369-72cjogxz 6765 12 hren hren NNP cord-015369-72cjogxz 6765 13 , , , cord-015369-72cjogxz 6765 14 zwangsläufig zwangsläufig NNP cord-015369-72cjogxz 6765 15 zu zu XX cord-015369-72cjogxz 6766 1 einem einem NNP cord-015369-72cjogxz 6766 2 gelegentlichen gelegentlichen NNP cord-015369-72cjogxz 6767 1 Bedarf Bedarf NNP cord-015369-72cjogxz 6768 1 postoperativer postoperativer NNP cord-015369-72cjogxz 6768 2 Schrittmacherimplantation Schrittmacherimplantation NNP cord-015369-72cjogxz 6769 1 i -PRON- PRP cord-015369-72cjogxz 6769 2 m be VBP cord-015369-72cjogxz 6769 3 Säuglingsalter Säuglingsalter NNP cord-015369-72cjogxz 6769 4 gefü gefü RB cord-015369-72cjogxz 6770 1 hrt hrt NNP cord-015369-72cjogxz 6771 1 Angeborene Angeborene NNP cord-015369-72cjogxz 6771 2 Herzfehler Herzfehler NNP cord-015369-72cjogxz 6771 3 bestanden bestanden NNP cord-015369-72cjogxz 6771 4 bei bei NNP cord-015369-72cjogxz 6771 5 19 19 CD cord-015369-72cjogxz 6771 6 Säuglingen Säuglingen NNP cord-015369-72cjogxz 6772 1 und und NNP cord-015369-72cjogxz 6772 2 erforderten erforderten NNP cord-015369-72cjogxz 6772 3 Herzoperationen Herzoperationen NNP cord-015369-72cjogxz 6772 4 mit mit NNP cord-015369-72cjogxz 6772 5 folgender folgender NNP cord-015369-72cjogxz 6772 6 , , , cord-015369-72cjogxz 6772 7 meist meist NNP cord-015369-72cjogxz 6772 8 iatrogener iatrogener NNP cord-015369-72cjogxz 6773 1 Rhythmusstörung Rhythmusstörung NNP cord-015369-72cjogxz 6773 2 Bei Bei NNP cord-015369-72cjogxz 6773 3 allen allen NNP cord-015369-72cjogxz 6773 4 Säuglingen Säuglingen NNP cord-015369-72cjogxz 6774 1 wurde wurde NNP cord-015369-72cjogxz 6774 2 der der NNP cord-015369-72cjogxz 6774 3 Generator Generator NNP cord-015369-72cjogxz 6774 4 zunächst zunächst NNP cord-015369-72cjogxz 6774 5 in in IN cord-015369-72cjogxz 6774 6 einer einer NNP cord-015369-72cjogxz 6774 7 submuskulären submuskulären NNP cord-015369-72cjogxz 6774 8 Tasche Tasche NNP cord-015369-72cjogxz 6774 9 des des FW cord-015369-72cjogxz 6774 10 rechten rechten NNP cord-015369-72cjogxz 6774 11 Mittel Mittel NNP cord-015369-72cjogxz 6774 12 - - HYPH cord-015369-72cjogxz 6774 13 oder oder NNP cord-015369-72cjogxz 6774 14 Unterbauches Unterbauches NNP cord-015369-72cjogxz 6774 15 eingebracht eingebracht NNP cord-015369-72cjogxz 6774 16 , , , cord-015369-72cjogxz 6775 1 die die VB cord-015369-72cjogxz 6776 1 Elektroden Elektroden NNP cord-015369-72cjogxz 6776 2 entweder entweder NN cord-015369-72cjogxz 6776 3 epikardial epikardial JJ cord-015369-72cjogxz 6776 4 platziert platziert NNP cord-015369-72cjogxz 6776 5 oder oder NNP cord-015369-72cjogxz 6776 6 über über NNP cord-015369-72cjogxz 6776 7 die die VBP cord-015369-72cjogxz 6776 8 rechte rechte NNP cord-015369-72cjogxz 6776 9 A. A. NNP cord-015369-72cjogxz 6776 10 subclavia subclavia NNP cord-015369-72cjogxz 6776 11 ( ( -LRB- cord-015369-72cjogxz 6776 12 5 5 CD cord-015369-72cjogxz 6776 13 ) ) -RRB- cord-015369-72cjogxz 6776 14 bzw bzw NNP cord-015369-72cjogxz 6776 15 . . . cord-015369-72cjogxz 6777 1 die die VB cord-015369-72cjogxz 6777 2 A. A. NNP cord-015369-72cjogxz 6777 3 jugularis jugularis NNP cord-015369-72cjogxz 6777 4 ( ( -LRB- cord-015369-72cjogxz 6777 5 4 4 CD cord-015369-72cjogxz 6777 6 ) ) -RRB- cord-015369-72cjogxz 6777 7 eingebracht eingebracht NNP cord-015369-72cjogxz 6777 8 , , , cord-015369-72cjogxz 6777 9 in in IN cord-015369-72cjogxz 6777 10 einem einem NNP cord-015369-72cjogxz 6777 11 Fall Fall NNP cord-015369-72cjogxz 6777 12 transatrial transatrial NNP cord-015369-72cjogxz 6777 13 . . . cord-015369-72cjogxz 6778 1 I -PRON- PRP cord-015369-72cjogxz 6778 2 m be VBP cord-015369-72cjogxz 6778 3 Kollektiv Kollektiv NNP cord-015369-72cjogxz 6778 4 mit mit NNP cord-015369-72cjogxz 6778 5 angeborenem angeborenem NNP cord-015369-72cjogxz 6778 6 AV AV NNP cord-015369-72cjogxz 6778 7 - - HYPH cord-015369-72cjogxz 6778 8 Block Block NNP cord-015369-72cjogxz 6778 9 gab gab NN cord-015369-72cjogxz 6779 1 es es XX cord-015369-72cjogxz 6780 1 keine keine NNP cord-015369-72cjogxz 6780 2 perioperativen perioperativen NNP cord-015369-72cjogxz 6780 3 Todesfälle Todesfälle NNP cord-015369-72cjogxz 6780 4 , , , cord-015369-72cjogxz 6781 1 bei bei NNP cord-015369-72cjogxz 6781 2 angeborenem angeborenem NNP cord-015369-72cjogxz 6781 3 Herzfehler Herzfehler NNP cord-015369-72cjogxz 6781 4 sind sind NNP cord-015369-72cjogxz 6781 5 2 2 CD cord-015369-72cjogxz 6782 1 Patienten Patienten NNP cord-015369-72cjogxz 6782 2 ( ( -LRB- cord-015369-72cjogxz 6783 1 10,5 10,5 CD cord-015369-72cjogxz 6783 2 % % NN cord-015369-72cjogxz 6783 3 ) ) -RRB- cord-015369-72cjogxz 6783 4 verstorben verstorben NN cord-015369-72cjogxz 6783 5 : : : cord-015369-72cjogxz 6784 1 ein ein NNP cord-015369-72cjogxz 6784 2 Neugeborener Neugeborener NNP cord-015369-72cjogxz 6784 3 mit mit NNP cord-015369-72cjogxz 6784 4 1500 1500 CD cord-015369-72cjogxz 6784 5 g g NNP cord-015369-72cjogxz 6784 6 Körpergewicht Körpergewicht NNP cord-015369-72cjogxz 6784 7 und und IN cord-015369-72cjogxz 6784 8 komplexem komplexem NNP cord-015369-72cjogxz 6784 9 Syndrom Syndrom NNP cord-015369-72cjogxz 6784 10 nach nach NN cord-015369-72cjogxz 6784 11 Verschluss Verschluss NNP cord-015369-72cjogxz 6784 12 eines eines NNP cord-015369-72cjogxz 6784 13 Ductus Ductus NNP cord-015369-72cjogxz 6784 14 Botalli Botalli NNP cord-015369-72cjogxz 6785 1 und und NNP cord-015369-72cjogxz 6786 1 i -PRON- PRP cord-015369-72cjogxz 6786 2 m be VBP cord-015369-72cjogxz 6786 3 Insgesamt Insgesamt NNP cord-015369-72cjogxz 6786 4 wurden wurden NNP cord-015369-72cjogxz 6786 5 bei bei NNP cord-015369-72cjogxz 6786 6 diesen diesen NNP cord-015369-72cjogxz 6787 1 19 19 CD cord-015369-72cjogxz 6787 2 Patienten Patienten NNP cord-015369-72cjogxz 6787 3 bislang bislang NNP cord-015369-72cjogxz 6788 1 49 49 CD cord-015369-72cjogxz 6788 2 Folgeeingriffe Folgeeingriffe NNP cord-015369-72cjogxz 6788 3 vorgenommen vorgenomman NNS cord-015369-72cjogxz 6788 4 ( ( -LRB- cord-015369-72cjogxz 6788 5 1,9 1,9 CD cord-015369-72cjogxz 6788 6 / / SYM cord-015369-72cjogxz 6788 7 Patient Patient NNP cord-015369-72cjogxz 6788 8 ) ) -RRB- cord-015369-72cjogxz 6788 9 : : : cord-015369-72cjogxz 6789 1 vorrangig vorrangig NNP cord-015369-72cjogxz 6789 2 wachstumsbedingte wachstumsbedingte NNP cord-015369-72cjogxz 6790 1 Anpassungen Anpassungen NNP cord-015369-72cjogxz 6790 2 des des NNP cord-015369-72cjogxz 6790 3 Systems Systems NNP cord-015369-72cjogxz 6790 4 sowie sowie NNP cord-015369-72cjogxz 6790 5 Aufrüstung Aufrüstung NNP cord-015369-72cjogxz 6791 1 i -PRON- PRP cord-015369-72cjogxz 6791 2 m be VBP cord-015369-72cjogxz 6791 3 Betriebsmodus Betriebsmodus NNP cord-015369-72cjogxz 6791 4 . . . cord-015369-72cjogxz 6792 1 Die die VB cord-015369-72cjogxz 6792 2 moderne moderne FW cord-015369-72cjogxz 6792 3 Schrittmacherchirurgie Schrittmacherchirurgie NNP cord-015369-72cjogxz 6792 4 gewährleistet gewährleistet NNP cord-015369-72cjogxz 6792 5 auch auch NNP cord-015369-72cjogxz 6793 1 i i PRP cord-015369-72cjogxz 6794 1 m m LS cord-015369-72cjogxz 6795 1 Neugeborenen Neugeborenen NNP cord-015369-72cjogxz 6795 2 - - HYPH cord-015369-72cjogxz 6795 3 und und NNP cord-015369-72cjogxz 6796 1 Säuglingsalter Säuglingsalter NNP cord-015369-72cjogxz 6796 2 eine eine NNP cord-015369-72cjogxz 6797 1 uneingeschränkte uneingeschränkte NNP cord-015369-72cjogxz 6797 2 Entwicklung Entwicklung NNP cord-015369-72cjogxz 6797 3 mit mit NNP cord-015369-72cjogxz 6797 4 hervorragender hervorragender NNP cord-015369-72cjogxz 6797 5 Lebensqualität Lebensqualität NNPS cord-015369-72cjogxz 6797 6 , , , cord-015369-72cjogxz 6798 1 nur nur NNP cord-015369-72cjogxz 6798 2 durchbrochen durchbrochen NNP cord-015369-72cjogxz 6798 3 von von NNP cord-015369-72cjogxz 6798 4 hauptsächlich hauptsächlich NNP cord-015369-72cjogxz 6798 5 wachstumsbedingt wachstumsbedingt NNP cord-015369-72cjogxz 6798 6 erforderlichen erforderlichen NNP cord-015369-72cjogxz 6798 7 Folgeeingriffen Folgeeingriffen NNP cord-015369-72cjogxz 6798 8 Acknowledgments acknowledgment NNS cord-015369-72cjogxz 6798 9 . . . cord-015369-72cjogxz 6799 1 This this DT cord-015369-72cjogxz 6799 2 study study NN cord-015369-72cjogxz 6799 3 was be VBD cord-015369-72cjogxz 6799 4 supported support VBN cord-015369-72cjogxz 6799 5 by by IN cord-015369-72cjogxz 6799 6 Mammamia Mammamia NNP cord-015369-72cjogxz 6799 7 . . . cord-015369-72cjogxz 6800 1 We -PRON- PRP cord-015369-72cjogxz 6800 2 also also RB cord-015369-72cjogxz 6800 3 thank thank VBP cord-015369-72cjogxz 6800 4 all all DT cord-015369-72cjogxz 6800 5 experts expert NNS cord-015369-72cjogxz 6800 6 and and CC cord-015369-72cjogxz 6800 7 non non NNS cord-015369-72cjogxz 6800 8 - - NNS cord-015369-72cjogxz 6800 9 experts expert NNS cord-015369-72cjogxz 6800 10 for for IN cord-015369-72cjogxz 6800 11 their -PRON- PRP$ cord-015369-72cjogxz 6800 12 time time NN cord-015369-72cjogxz 6800 13 - - HYPH cord-015369-72cjogxz 6800 14 consuming consume VBG cord-015369-72cjogxz 6800 15 subjective subjective JJ cord-015369-72cjogxz 6800 16 evaluation evaluation NN cord-015369-72cjogxz 6800 17 . . . cord-015369-72cjogxz 6801 1 Methodik Methodik NNP cord-015369-72cjogxz 6801 2 . . . cord-015369-72cjogxz 6802 1 Der Der NNP cord-015369-72cjogxz 6803 1 49-jährige 49-jährige CD cord-015369-72cjogxz 6803 2 Bechterew Bechterew NNP cord-015369-72cjogxz 6803 3 -Patient -patient NN cord-015369-72cjogxz 6803 4 wurde wurde NNP cord-015369-72cjogxz 6803 5 aufgrund aufgrund JJ cord-015369-72cjogxz 6804 1 einer einer NNP cord-015369-72cjogxz 6804 2 perforierten perforierten NNP cord-015369-72cjogxz 6804 3 Sigmadivertikulitis Sigmadivertikulitis NNP cord-015369-72cjogxz 6804 4 mit mit NNP cord-015369-72cjogxz 6804 5 stercoraler stercoraler NNP cord-015369-72cjogxz 6804 6 Peritonitis Peritonitis NNP cord-015369-72cjogxz 6804 7 notfalllaparotomiert notfalllaparotomiert NNP cord-015369-72cjogxz 6804 8 , , , cord-015369-72cjogxz 6804 9 wobei wobei NNP cord-015369-72cjogxz 6804 10 eine eine NNP cord-015369-72cjogxz 6804 11 Stomasituation Stomasituation NNP cord-015369-72cjogxz 6804 12 nach nach NN cord-015369-72cjogxz 6804 13 Hartmann Hartmann NNP cord-015369-72cjogxz 6804 14 angelegt angelegt RB cord-015369-72cjogxz 6804 15 werden werden NNP cord-015369-72cjogxz 6804 16 musste musste NNP cord-015369-72cjogxz 6804 17 , , , cord-015369-72cjogxz 6804 18 sowie sowie NNP cord-015369-72cjogxz 6804 19 eine eine NNP cord-015369-72cjogxz 6804 20 Dünndarmteilresektion Dünndarmteilresektion NNP cord-015369-72cjogxz 6804 21 mit mit NNP cord-015369-72cjogxz 6804 22 einem einem NNP cord-015369-72cjogxz 6804 23 endständigen endständigen NNP cord-015369-72cjogxz 6804 24 Ileostoma Ileostoma NNP cord-015369-72cjogxz 6804 25 erfolgte erfolgte NN cord-015369-72cjogxz 6804 26 . . . cord-015369-72cjogxz 6805 1 Es Es NNP cord-015369-72cjogxz 6805 2 entwickelte entwickelte NNP cord-015369-72cjogxz 6805 3 sich sich NNP cord-015369-72cjogxz 6805 4 eine eine NNP cord-015369-72cjogxz 6805 5 stercorale stercorale NNP cord-015369-72cjogxz 6805 6 Peritonitis Peritonitis NNP cord-015369-72cjogxz 6805 7 , , , cord-015369-72cjogxz 6805 8 welche welche NNP cord-015369-72cjogxz 6805 9 mit mit NNP cord-015369-72cjogxz 6805 10 einem einem NNP cord-015369-72cjogxz 6805 11 , , , cord-015369-72cjogxz 6805 12 , , , cord-015369-72cjogxz 6805 13 KCI KCI NNP cord-015369-72cjogxz 6805 14 - - HYPH cord-015369-72cjogxz 6805 15 V.A.C.-Abdominaldressing V.A.C.-Abdominaldressing NNP cord-015369-72cjogxz 6805 16 ' ' '' cord-015369-72cjogxz 6805 17 ' ' '' cord-015369-72cjogxz 6806 1 i -PRON- PRP cord-015369-72cjogxz 6806 2 m be VBP cord-015369-72cjogxz 6806 3 Sinne Sinne NNP cord-015369-72cjogxz 6806 4 eines eines NNPS cord-015369-72cjogxz 6806 5 Laparostomas Laparostomas NNP cord-015369-72cjogxz 6806 6 behandelt behandelt NNP cord-015369-72cjogxz 6806 7 wurde wurde VBD cord-015369-72cjogxz 6806 8 . . . cord-015369-72cjogxz 6807 1 Weiter Weiter NNP cord-015369-72cjogxz 6807 2 entwickelte entwickelte NNP cord-015369-72cjogxz 6807 3 sich sich NNP cord-015369-72cjogxz 6807 4 eine eine NNP cord-015369-72cjogxz 6807 5 Dünndarmfistel Dünndarmfistel NNP cord-015369-72cjogxz 6807 6 . . . cord-015369-72cjogxz 6808 1 Nach Nach NNP cord-015369-72cjogxz 6808 2 frustranen frustranen NNP cord-015369-72cjogxz 6809 1 Reoperationsversuchen Reoperationsversuchen NNP cord-015369-72cjogxz 6809 2 entschied entschied JJ cord-015369-72cjogxz 6809 3 man man NN cord-015369-72cjogxz 6809 4 sich sich NNP cord-015369-72cjogxz 6809 5 , , , cord-015369-72cjogxz 6809 6 die die VB cord-015369-72cjogxz 6809 7 gegebene gegebene NN cord-015369-72cjogxz 6810 1 Fistelsituation fistelsituation NN cord-015369-72cjogxz 6810 2 seitens seiten NNS cord-015369-72cjogxz 6810 3 des des NNP cord-015369-72cjogxz 6810 4 Therapieansatzes Therapieansatzes NNP cord-015369-72cjogxz 6810 5 als als NN cord-015369-72cjogxz 6810 6 zweites zweites NN cord-015369-72cjogxz 6810 7 Stoma Stoma NNP cord-015369-72cjogxz 6810 8 zu zu NNP cord-015369-72cjogxz 6810 9 behandeln behandeln NNP cord-015369-72cjogxz 6810 10 und und IN cord-015369-72cjogxz 6810 11 arbeitete arbeitete NNP cord-015369-72cjogxz 6810 12 daher daher NNP cord-015369-72cjogxz 6810 13 auf auf NNP cord-015369-72cjogxz 6810 14 einen einen NNP cord-015369-72cjogxz 6810 15 entsprechenden entsprechenden JJ cord-015369-72cjogxz 6810 16 Bauchdeckenverschluss Bauchdeckenverschluss NNP cord-015369-72cjogxz 6810 17 hin hin NNP cord-015369-72cjogxz 6810 18 . . . cord-015369-72cjogxz 6811 1 Um um UH cord-015369-72cjogxz 6811 2 eine eine FW cord-015369-72cjogxz 6811 3 schnellere schnellere JJ cord-015369-72cjogxz 6811 4 Abheilung Abheilung NNP cord-015369-72cjogxz 6811 5 zu zu NNP cord-015369-72cjogxz 6811 6 erreichen erreichen NNP cord-015369-72cjogxz 6811 7 , , , cord-015369-72cjogxz 6812 1 entschied entschied NNP cord-015369-72cjogxz 6812 2 man man NNP cord-015369-72cjogxz 6812 3 sich sich NNP cord-015369-72cjogxz 6812 4 schließlich schließlich NNP cord-015369-72cjogxz 6812 5 nach nach NNP cord-015369-72cjogxz 6812 6 der der NNP cord-015369-72cjogxz 6812 7 V.A.C.-Versorgung V.A.C.-Versorgung NNP cord-015369-72cjogxz 6812 8 für für IN cord-015369-72cjogxz 6813 1 eine eine NNP cord-015369-72cjogxz 6813 2 Defektdeckung Defektdeckung NNP cord-015369-72cjogxz 6813 3 mittels mittels NNP cord-015369-72cjogxz 6813 4 Mesh Mesh NNP cord-015369-72cjogxz 6813 5 - - HYPH cord-015369-72cjogxz 6813 6 Craft Craft NNP cord-015369-72cjogxz 6813 7 - - HYPH cord-015369-72cjogxz 6813 8 Transplantat Transplantat NNP cord-015369-72cjogxz 6813 9 . . . cord-015369-72cjogxz 6814 1 Dieses Dieses NNP cord-015369-72cjogxz 6814 2 konnte konnte NNP cord-015369-72cjogxz 6814 3 mittels mittels NNP cord-015369-72cjogxz 6814 4 V.A.C.-Verband V.A.C.-Verband NNP cord-015369-72cjogxz 6814 5 zum zum NNP cord-015369-72cjogxz 6814 6 Anheilen Anheilen NNP cord-015369-72cjogxz 6814 7 gebracht gebracht FW cord-015369-72cjogxz 6814 8 werden werden NNP cord-015369-72cjogxz 6814 9 . . . cord-015369-72cjogxz 6815 1 Nach Nach NNP cord-015369-72cjogxz 6815 2 klinischer klinischer NNP cord-015369-72cjogxz 6815 3 Stabilisierung Stabilisierung NNP cord-015369-72cjogxz 6815 4 erfolgte erfolgte NN cord-015369-72cjogxz 6815 5 eine eine NNP cord-015369-72cjogxz 6815 6 Dünndarm Dünndarm NNP cord-015369-72cjogxz 6815 7 - - HYPH cord-015369-72cjogxz 6815 8 Reanastomosierung Reanastomosierung NNP cord-015369-72cjogxz 6815 9 . . . cord-015369-72cjogxz 6816 1 Allerdings Allerdings NNP cord-015369-72cjogxz 6816 2 entwickelte entwickelte NNP cord-015369-72cjogxz 6816 3 sich sich NNP cord-015369-72cjogxz 6816 4 in in IN cord-015369-72cjogxz 6816 5 der der NNP cord-015369-72cjogxz 6816 6 Folge Folge NNP cord-015369-72cjogxz 6816 7 erneut erneut NNP cord-015369-72cjogxz 6816 8 eine eine NNP cord-015369-72cjogxz 6816 9 Anastomoseninsuffizienz Anastomoseninsuffizienz NNP cord-015369-72cjogxz 6816 10 mit mit NNP cord-015369-72cjogxz 6816 11 Ausbildung Ausbildung NNP cord-015369-72cjogxz 6816 12 einer einer NNP cord-015369-72cjogxz 6816 13 Dünndarmfistel Dünndarmfistel NNP cord-015369-72cjogxz 6816 14 . . . cord-015369-72cjogxz 6817 1 Eine Eine NNP cord-015369-72cjogxz 6817 2 konservative konservative NNP cord-015369-72cjogxz 6818 1 Verbandstechnik Verbandstechnik NNP cord-015369-72cjogxz 6818 2 gestaltete gestaltete NNP cord-015369-72cjogxz 6818 3 sich sich NNP cord-015369-72cjogxz 6818 4 in in IN cord-015369-72cjogxz 6818 5 dieser dieser NNP cord-015369-72cjogxz 6818 6 Situation Situation NNP cord-015369-72cjogxz 6818 7 als als NNP cord-015369-72cjogxz 6818 8 schlichtweg schlichtweg JJ cord-015369-72cjogxz 6818 9 unmöglich unmöglich NN cord-015369-72cjogxz 6818 10 . . . cord-015369-72cjogxz 6819 1 Da Da NNP cord-015369-72cjogxz 6819 2 aufgrund aufgrund NNP cord-015369-72cjogxz 6819 3 der der NNP cord-015369-72cjogxz 6819 4 Vorgeschichte Vorgeschichte NNP cord-015369-72cjogxz 6819 5 eine eine NNP cord-015369-72cjogxz 6819 6 erneute erneute NN cord-015369-72cjogxz 6820 1 Spalthautdeckung Spalthautdeckung NNP cord-015369-72cjogxz 6820 2 der der NNP cord-015369-72cjogxz 6820 3 wieder wieder NNP cord-015369-72cjogxz 6820 4 klaffenden klaffenden JJ cord-015369-72cjogxz 6820 5 Bauchwunde Bauchwunde NNP cord-015369-72cjogxz 6820 6 nicht nicht NNP cord-015369-72cjogxz 6820 7 möglich möglich NNP cord-015369-72cjogxz 6820 8 erschien erschien NNP cord-015369-72cjogxz 6820 9 , , , cord-015369-72cjogxz 6820 10 kam kam NNP cord-015369-72cjogxz 6820 11 wieder wieder NNP cord-015369-72cjogxz 6820 12 eine eine NNP cord-015369-72cjogxz 6820 13 Versorgung Versorgung NNP cord-015369-72cjogxz 6820 14 mit mit NNP cord-015369-72cjogxz 6820 15 einem einem NNP cord-015369-72cjogxz 6820 16 V.A.C.-System V.A.C.-System NNP cord-015369-72cjogxz 6820 17 zum zum NNP cord-015369-72cjogxz 6820 18 Einsatz Einsatz NNP cord-015369-72cjogxz 6820 19 . . . cord-015369-72cjogxz 6821 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6821 2 . . . cord-015369-72cjogxz 6822 1 Die die VB cord-015369-72cjogxz 6822 2 Wundfläche Wundfläche NNP cord-015369-72cjogxz 6822 3 konnte konnte NNP cord-015369-72cjogxz 6822 4 damit damit NNP cord-015369-72cjogxz 6822 5 in in IN cord-015369-72cjogxz 6822 6 wenigen wenigen NNP cord-015369-72cjogxz 6822 7 Wochen Wochen NNP cord-015369-72cjogxz 6822 8 auf auf NNP cord-015369-72cjogxz 6823 1 fast fast RB cord-015369-72cjogxz 6823 2 die die JJ cord-015369-72cjogxz 6824 1 Hälfte Hälfte NNP cord-015369-72cjogxz 6824 2 reduziert reduziert NNP cord-015369-72cjogxz 6824 3 und und NNP cord-015369-72cjogxz 6824 4 mittels mittels NNP cord-015369-72cjogxz 6824 5 Stomaplatte Stomaplatte NNP cord-015369-72cjogxz 6824 6 versorgt versorgt NN cord-015369-72cjogxz 6824 7 werden werden NNP cord-015369-72cjogxz 6824 8 . . . cord-015369-72cjogxz 6825 1 Die die VB cord-015369-72cjogxz 6825 2 Verbandstechnik Verbandstechnik NNP cord-015369-72cjogxz 6825 3 erlaubte erlaubte XX cord-015369-72cjogxz 6825 4 es es NNP cord-015369-72cjogxz 6825 5 , , , cord-015369-72cjogxz 6825 6 dass dass NNP cord-015369-72cjogxz 6825 7 durch durch NNP cord-015369-72cjogxz 6825 8 eingeschultes eingeschultes NNP cord-015369-72cjogxz 6826 1 Pflegepersonal Pflegepersonal NNP cord-015369-72cjogxz 6826 2 eine eine NNP cord-015369-72cjogxz 6826 3 Verbandsüberwachung Verbandsüberwachung NNP cord-015369-72cjogxz 6826 4 und und IN cord-015369-72cjogxz 6826 5 sogar sogar NNP cord-015369-72cjogxz 6826 6 Neuanlage Neuanlage NNP cord-015369-72cjogxz 6826 7 möglich möglich NN cord-015369-72cjogxz 6826 8 wurde wurde NN cord-015369-72cjogxz 6826 9 . . . cord-015369-72cjogxz 6827 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6827 2 . . . cord-015369-72cjogxz 6828 1 Die die VB cord-015369-72cjogxz 6828 2 erreichten erreichten NNP cord-015369-72cjogxz 6828 3 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6828 4 bei bei NNP cord-015369-72cjogxz 6828 5 diesem diesem JJ cord-015369-72cjogxz 6828 6 primär primär NN cord-015369-72cjogxz 6828 7 lebensbedrohlichen lebensbedrohlichen NNP cord-015369-72cjogxz 6828 8 Krankheitsbild Krankheitsbild NNP cord-015369-72cjogxz 6828 9 und und NNP cord-015369-72cjogxz 6828 10 der der NNP cord-015369-72cjogxz 6828 11 rezidivierenden rezidivierenden NNP cord-015369-72cjogxz 6829 1 Entwicklung Entwicklung NNP cord-015369-72cjogxz 6829 2 von von NNP cord-015369-72cjogxz 6829 3 Dünndarmfisteln Dünndarmfisteln NNP cord-015369-72cjogxz 6829 4 wären wären NNP cord-015369-72cjogxz 6829 5 ohne ohne NNP cord-015369-72cjogxz 6829 6 innovative innovative JJ cord-015369-72cjogxz 6829 7 chirurgisch chirurgisch JJ cord-015369-72cjogxz 6829 8 - - HYPH cord-015369-72cjogxz 6829 9 pflegerische pflegerische NN cord-015369-72cjogxz 6829 10 Betreuung Betreuung NNP cord-015369-72cjogxz 6829 11 und und IN cord-015369-72cjogxz 6829 12 der der NNP cord-015369-72cjogxz 6829 13 wochenlang wochenlang NNP cord-015369-72cjogxz 6829 14 durchgeführten durchgeführten NNP cord-015369-72cjogxz 6830 1 V.A.C.-Therapie V.A.C.-Therapie NNP cord-015369-72cjogxz 6831 1 wohl wohl NNP cord-015369-72cjogxz 6831 2 kaum kaum NNP cord-015369-72cjogxz 6831 3 zu zu NNP cord-015369-72cjogxz 6831 4 erzielen erzielen NNP cord-015369-72cjogxz 6831 5 gewesen gewesen NNP cord-015369-72cjogxz 6831 6 , , , cord-015369-72cjogxz 6831 7 das das NNP cord-015369-72cjogxz 6831 8 Verfahren Verfahren NNP cord-015369-72cjogxz 6831 9 konnte konnte NNP cord-015369-72cjogxz 6831 10 klar klar NNP cord-015369-72cjogxz 6831 11 überzeugen überzeugen NNP cord-015369-72cjogxz 6831 12 . . . cord-015369-72cjogxz 6832 1 Unterdrucktherapiebesteht Unterdrucktherapiebesteht NNP cord-015369-72cjogxz 6832 2 ein ein NN cord-015369-72cjogxz 6832 3 qualitativer qualitativer XX cord-015369-72cjogxz 6833 1 Unterschied Unterschied NNP cord-015369-72cjogxz 6833 2 zwischen zwischen NN cord-015369-72cjogxz 6833 3 den den NN cord-015369-72cjogxz 6833 4 verschiedenen verschiedenen NNP cord-015369-72cjogxz 6833 5 Systemen Systemen NNP cord-015369-72cjogxz 6833 6 ? ? . cord-015369-72cjogxz 6833 7 _SP cord-015369-72cjogxz 6834 1 Tumor tumor NN cord-015369-72cjogxz 6834 2 - - HYPH cord-015369-72cjogxz 6834 3 induced induce VBN cord-015369-72cjogxz 6834 4 bleeding bleed VBG cord-015369-72cjogxz 6834 5 by by IN cord-015369-72cjogxz 6834 6 affection affection NN cord-015369-72cjogxz 6834 7 of of IN cord-015369-72cjogxz 6834 8 the the DT cord-015369-72cjogxz 6834 9 axillar axillar NNP cord-015369-72cjogxz 6834 10 artery artery NN cord-015369-72cjogxz 6834 11 due due IN cord-015369-72cjogxz 6834 12 to to IN cord-015369-72cjogxz 6834 13 recurrent recurrent JJ cord-015369-72cjogxz 6834 14 tumor tumor NN cord-015369-72cjogxz 6834 15 growth growth NN cord-015369-72cjogxz 6834 16 of of IN cord-015369-72cjogxz 6834 17 breast breast NN cord-015369-72cjogxz 6834 18 carcinoma carcinoma NN cord-015369-72cjogxz 6834 19 with with IN cord-015369-72cjogxz 6834 20 successful successful JJ cord-015369-72cjogxz 6834 21 endovascular endovascular JJ cord-015369-72cjogxz 6834 22 treatment treatment NN cord-015369-72cjogxz 6834 23 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6834 24 . . . cord-015369-72cjogxz 6835 1 Die die VB cord-015369-72cjogxz 6835 2 Tumor tumor NN cord-015369-72cjogxz 6835 3 - - HYPH cord-015369-72cjogxz 6835 4 induzierte induzierte NNS cord-015369-72cjogxz 6835 5 Blutung Blutung NNP cord-015369-72cjogxz 6835 6 aus aus NNP cord-015369-72cjogxz 6836 1 einem einem NNP cord-015369-72cjogxz 6836 2 Stammgefäß Stammgefäß NNP cord-015369-72cjogxz 6837 1 ist ist NNP cord-015369-72cjogxz 6837 2 ein ein NNP cord-015369-72cjogxz 6837 3 seltenes seltenes NNPS cord-015369-72cjogxz 6837 4 Ereignis Ereignis NNP cord-015369-72cjogxz 6837 5 , , , cord-015369-72cjogxz 6837 6 kann kann NNP cord-015369-72cjogxz 6837 7 jedoch jedoch NNP cord-015369-72cjogxz 6837 8 lebensbedrohlich lebensbedrohlich NNP cord-015369-72cjogxz 6837 9 in in IN cord-015369-72cjogxz 6837 10 Erscheinung Erscheinung NNP cord-015369-72cjogxz 6837 11 treten treten NNP cord-015369-72cjogxz 6837 12 . . . cord-015369-72cjogxz 6838 1 Methodik Methodik NNP cord-015369-72cjogxz 6838 2 . . . cord-015369-72cjogxz 6839 1 Es Es NNP cord-015369-72cjogxz 6839 2 wird wird NNP cord-015369-72cjogxz 6839 3 die die VBP cord-015369-72cjogxz 6839 4 suffiziente suffiziente NNP cord-015369-72cjogxz 6839 5 alternative alternative NN cord-015369-72cjogxz 6839 6 Option option NN cord-015369-72cjogxz 6839 7 der der NN cord-015369-72cjogxz 6839 8 Blutstillung Blutstillung NNP cord-015369-72cjogxz 6839 9 bei bei NNP cord-015369-72cjogxz 6839 10 einem einem NNP cord-015369-72cjogxz 6840 1 außergewöhnlichen außergewöhnlichen NNP cord-015369-72cjogxz 6840 2 Casus Casus NNP cord-015369-72cjogxz 6840 3 mit mit NNP cord-015369-72cjogxz 6840 4 fortgeschrittenem fortgeschrittenem NN cord-015369-72cjogxz 6840 5 Tumorleiden Tumorleiden NNP cord-015369-72cjogxz 6840 6 und und IN cord-015369-72cjogxz 6840 7 Infiltrationsbedingter Infiltrationsbedingter NNP cord-015369-72cjogxz 6840 8 Blutung Blutung NNP cord-015369-72cjogxz 6840 9 demonstriert demonstriert NNP cord-015369-72cjogxz 6840 10 , , , cord-015369-72cjogxz 6840 11 die die VBP cord-015369-72cjogxz 6840 12 kaum kaum NNP cord-015369-72cjogxz 6840 13 konventionell konventionell NNP cord-015369-72cjogxz 6840 14 angehbar angehbar NNP cord-015369-72cjogxz 6840 15 erschien erschien NNP cord-015369-72cjogxz 6840 16 . . . cord-015369-72cjogxz 6841 1 Fallschilderung Fallschilderung NNP cord-015369-72cjogxz 6841 2 und und IN cord-015369-72cjogxz 6841 3 Therapieergebnis Therapieergebnis NNPS cord-015369-72cjogxz 6841 4 . . . cord-015369-72cjogxz 6842 1 Eine Eine NNP cord-015369-72cjogxz 6842 2 70-jährige 70-jährige CD cord-015369-72cjogxz 6842 3 Patientin Patientin NNP cord-015369-72cjogxz 6842 4 wurde wurde NN cord-015369-72cjogxz 6842 5 mit mit NNP cord-015369-72cjogxz 6842 6 hämorrhagischem hämorrhagischem NNP cord-015369-72cjogxz 6842 7 Schock Schock NNP cord-015369-72cjogxz 6842 8 intubiert intubiert NNP cord-015369-72cjogxz 6843 1 und und NNP cord-015369-72cjogxz 6844 1 beatmet beatmet NNP cord-015369-72cjogxz 6844 2 ü ü NNP cord-015369-72cjogxz 6845 1 ber ber NNP cord-015369-72cjogxz 6845 2 die die NNP cord-015369-72cjogxz 6846 1 Rettungsstelle Rettungsstelle NNP cord-015369-72cjogxz 6846 2 eingeliefert eingeliefert NNP cord-015369-72cjogxz 6846 3 und und NNP cord-015369-72cjogxz 6846 4 reanimiert reanimiert NNP cord-015369-72cjogxz 6846 5 . . . cord-015369-72cjogxz 6847 1 In in IN cord-015369-72cjogxz 6847 2 der der NNP cord-015369-72cjogxz 6847 3 Anamnese anamnese JJ cord-015369-72cjogxz 6847 4 war war NN cord-015369-72cjogxz 6848 1 ein ein NNP cord-015369-72cjogxz 6848 2 Z.n Z.n NNP cord-015369-72cjogxz 6848 3 . . . cord-015369-72cjogxz 6849 1 operativer operativer NNP cord-015369-72cjogxz 6849 2 Spaltung Spaltung NNP cord-015369-72cjogxz 6849 3 eines eines NNP cord-015369-72cjogxz 6850 1 Schweißdrü Schweißdrü NNP cord-015369-72cjogxz 6850 2 senabszesses senabszesse VBZ cord-015369-72cjogxz 6850 3 links link NNS cord-015369-72cjogxz 6850 4 - - HYPH cord-015369-72cjogxz 6850 5 axillär axillär NN cord-015369-72cjogxz 6850 6 vor vor NNP cord-015369-72cjogxz 6850 7 1 1 CD cord-015369-72cjogxz 6850 8 Jahr Jahr NNP cord-015369-72cjogxz 6850 9 mit mit NNP cord-015369-72cjogxz 6850 10 chronischer chronischer NNP cord-015369-72cjogxz 6850 11 Wundheilungsstörung Wundheilungsstörung NNP cord-015369-72cjogxz 6851 1 ( ( -LRB- cord-015369-72cjogxz 6851 2 mikrobiologischer mikrobiologischer NNP cord-015369-72cjogxz 6851 3 Abstrich Abstrich NNP cord-015369-72cjogxz 6851 4 : : : cord-015369-72cjogxz 6851 5 Gram gram NN cord-015369-72cjogxz 6851 6 - - HYPH cord-015369-72cjogxz 6851 7 negative negative JJ cord-015369-72cjogxz 6851 8 Stäbchen Stäbchen NNP cord-015369-72cjogxz 6851 9 , , , cord-015369-72cjogxz 6851 10 Candida Candida NNP cord-015369-72cjogxz 6851 11 ) ) -RRB- cord-015369-72cjogxz 6851 12 bei bei NNP cord-015369-72cjogxz 6851 13 inflammatorischem inflammatorischem NN cord-015369-72cjogxz 6851 14 Mamma Mamma NNP cord-015369-72cjogxz 6851 15 - - HYPH cord-015369-72cjogxz 6851 16 Karzinom Karzinom NNP cord-015369-72cjogxz 6851 17 links link NNS cord-015369-72cjogxz 6851 18 ( ( -LRB- cord-015369-72cjogxz 6851 19 histologisch histologisch NNP cord-015369-72cjogxz 6851 20 durch durch NNP cord-015369-72cjogxz 6851 21 Tumor Tumor NNP cord-015369-72cjogxz 6851 22 - - HYPH cord-015369-72cjogxz 6851 23 PE PE NNP cord-015369-72cjogxz 6851 24 gesichert gesichert NN cord-015369-72cjogxz 6851 25 ) ) -RRB- cord-015369-72cjogxz 6851 26 und und NNP cord-015369-72cjogxz 6851 27 erfolgter erfolgter NNP cord-015369-72cjogxz 6851 28 palliativer palliativer NNP cord-015369-72cjogxz 6851 29 Strahlenchemotherapie Strahlenchemotherapie NNP cord-015369-72cjogxz 6851 30 bekannt bekannt NNP cord-015369-72cjogxz 6851 31 . . . cord-015369-72cjogxz 6852 1 Die die VB cord-015369-72cjogxz 6852 2 sofortige sofortige NNP cord-015369-72cjogxz 6852 3 Notfallangiographie Notfallangiographie NNP cord-015369-72cjogxz 6852 4 via via IN cord-015369-72cjogxz 6852 5 A. A. NNP cord-015369-72cjogxz 6852 6 femoralis femoralis NNP cord-015369-72cjogxz 6852 7 sinistra sinistra NNP cord-015369-72cjogxz 6852 8 erbrachte erbrachte NNP cord-015369-72cjogxz 6853 1 eine eine NNP cord-015369-72cjogxz 6853 2 Blutung Blutung NNP cord-015369-72cjogxz 6853 3 aus aus NNP cord-015369-72cjogxz 6853 4 dem dem NNP cord-015369-72cjogxz 6853 5 proximalen proximalen NNP cord-015369-72cjogxz 6853 6 Segment Segment NNP cord-015369-72cjogxz 6853 7 der der NNP cord-015369-72cjogxz 6853 8 A. A. NNP cord-015369-72cjogxz 6853 9 axillaris axillaris JJ cord-015369-72cjogxz 6853 10 sinistra sinistra NNP cord-015369-72cjogxz 6853 11 . . . cord-015369-72cjogxz 6854 1 In in IN cord-015369-72cjogxz 6854 2 gleicher gleicher NNP cord-015369-72cjogxz 6854 3 Sitzung Sitzung NNP cord-015369-72cjogxz 6854 4 wurde wurde NNP cord-015369-72cjogxz 6854 5 interventionell interventionell NNP cord-015369-72cjogxz 6854 6 - - HYPH cord-015369-72cjogxz 6854 7 radiologisch radiologisch NNP cord-015369-72cjogxz 6854 8 ein ein NNP cord-015369-72cjogxz 6854 9 selbstexpandierender selbstexpandierender NNP cord-015369-72cjogxz 6854 10 endoluminaler endoluminaler NNP cord-015369-72cjogxz 6854 11 Stent Stent NNP cord-015369-72cjogxz 6855 1 ( ( -LRB- cord-015369-72cjogxz 6855 2 5 5 CD cord-015369-72cjogxz 6855 3 Â â CD cord-015369-72cjogxz 6855 4 40 40 CD cord-015369-72cjogxz 6855 5 mm mm NN cord-015369-72cjogxz 6855 6 Viabahn Viabahn NNP cord-015369-72cjogxz 6855 7 + + CC cord-015369-72cjogxz 6855 8 , , . cord-015369-72cjogxz 6856 1 Gore Gore NNP cord-015369-72cjogxz 6856 2 , , , cord-015369-72cjogxz 6856 3 Flagstaff Flagstaff NNP cord-015369-72cjogxz 6856 4 , , , cord-015369-72cjogxz 6856 5 USA USA NNP cord-015369-72cjogxz 6856 6 ) ) -RRB- cord-015369-72cjogxz 6856 7 ü ü NN cord-015369-72cjogxz 6857 1 ber ber NNP cord-015369-72cjogxz 6857 2 die die NNP cord-015369-72cjogxz 6858 1 Arterienläsion arterienläsion NN cord-015369-72cjogxz 6859 1 hinweg hinweg NNP cord-015369-72cjogxz 6859 2 platziert platziert NNP cord-015369-72cjogxz 6859 3 , , , cord-015369-72cjogxz 6859 4 die die VB cord-015369-72cjogxz 6859 5 eine eine NNP cord-015369-72cjogxz 6859 6 umgehende umgehende NNP cord-015369-72cjogxz 6859 7 suffiziente suffiziente NNP cord-015369-72cjogxz 6859 8 Blutstillung Blutstillung NNP cord-015369-72cjogxz 6859 9 erbrachte erbrachte NNP cord-015369-72cjogxz 6859 10 . . . cord-015369-72cjogxz 6860 1 Die die VB cord-015369-72cjogxz 6860 2 abschließende abschließende NNP cord-015369-72cjogxz 6860 3 Kontrollangiographie Kontrollangiographie NNP cord-015369-72cjogxz 6860 4 zeigte zeigte NNP cord-015369-72cjogxz 6860 5 die die VB cord-015369-72cjogxz 6861 1 korrekte korrekte NNP cord-015369-72cjogxz 6861 2 Stentlage Stentlage NNP cord-015369-72cjogxz 6861 3 mit mit NNP cord-015369-72cjogxz 6861 4 sicherer sicherer NNP cord-015369-72cjogxz 6861 5 peripherer peripherer NNP cord-015369-72cjogxz 6861 6 Perfusion Perfusion NNP cord-015369-72cjogxz 6861 7 i -PRON- PRP cord-015369-72cjogxz 6861 8 m be VBP cord-015369-72cjogxz 6861 9 brachialen brachialen NNP cord-015369-72cjogxz 6862 1 Abstromgebiet Abstromgebiet NNP cord-015369-72cjogxz 6862 2 ohne ohne NNP cord-015369-72cjogxz 6862 3 weiteren weiteren NNP cord-015369-72cjogxz 6862 4 Blutungsnachweis Blutungsnachweis NNP cord-015369-72cjogxz 6862 5 . . . cord-015369-72cjogxz 6863 1 Am be VBP cord-015369-72cjogxz 6863 2 7 7 CD cord-015369-72cjogxz 6863 3 . . . cord-015369-72cjogxz 6864 1 postinterventionellen postinterventionellen NNP cord-015369-72cjogxz 6864 2 Tag Tag NNP cord-015369-72cjogxz 6864 3 wurde wurde NNP cord-015369-72cjogxz 6864 4 die die VBP cord-015369-72cjogxz 6865 1 Patientin Patientin NNP cord-015369-72cjogxz 6865 2 nach nach NNP cord-015369-72cjogxz 6865 3 zwischenzeitlicher zwischenzeitlicher NNP cord-015369-72cjogxz 6866 1 antiseptischer antiseptischer NNP cord-015369-72cjogxz 6866 2 Wundpflege Wundpflege NNP cord-015369-72cjogxz 6866 3 links link NNS cord-015369-72cjogxz 6866 4 - - HYPH cord-015369-72cjogxz 6866 5 axillar axillar JJ cord-015369-72cjogxz 6866 6 entlassen entlassen NNP cord-015369-72cjogxz 6866 7 . . . cord-015369-72cjogxz 6867 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6867 2 . . . cord-015369-72cjogxz 6868 1 Die die VB cord-015369-72cjogxz 6868 2 endovaskuläre endovaskuläre NNP cord-015369-72cjogxz 6868 3 Versorgung Versorgung NNP cord-015369-72cjogxz 6868 4 umgrenzter umgrenzter NN cord-015369-72cjogxz 6868 5 arterieller arterieller NNP cord-015369-72cjogxz 6869 1 Läsionen Läsionen NNP cord-015369-72cjogxz 6869 2 ist ist NNP cord-015369-72cjogxz 6869 3 eine eine NNP cord-015369-72cjogxz 6869 4 geeignete geeignete NNP cord-015369-72cjogxz 6869 5 Option Option NNP cord-015369-72cjogxz 6869 6 , , , cord-015369-72cjogxz 6869 7 in in IN cord-015369-72cjogxz 6869 8 schwierig schwierig NNP cord-015369-72cjogxz 6869 9 zugänglichen zugänglichen NNP cord-015369-72cjogxz 6869 10 Arteriensegmenten Arteriensegmenten NNP cord-015369-72cjogxz 6869 11 aufgrund aufgrund NNP cord-015369-72cjogxz 6869 12 der der NNP cord-015369-72cjogxz 6869 13 anatomischen anatomischen NNP cord-015369-72cjogxz 6869 14 Lokalisation Lokalisation NNP cord-015369-72cjogxz 6869 15 , , , cord-015369-72cjogxz 6869 16 Begleiterkrankungen Begleiterkrankungen NNP cord-015369-72cjogxz 6870 1 und und NNP cord-015369-72cjogxz 6870 2 Therapiekonsequenzen Therapiekonsequenzen NNP cord-015369-72cjogxz 6870 3 eine eine NNP cord-015369-72cjogxz 6871 1 suffiziente suffiziente NNP cord-015369-72cjogxz 6871 2 Blutstillung Blutstillung NNP cord-015369-72cjogxz 6871 3 herbeizuführen herbeizuführen NNP cord-015369-72cjogxz 6871 4 und und IN cord-015369-72cjogxz 6871 5 eine eine NNP cord-015369-72cjogxz 6871 6 aufwändige aufwändige NNP cord-015369-72cjogxz 6871 7 , , , cord-015369-72cjogxz 6871 8 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6871 9 . . . cord-015369-72cjogxz 6872 1 , , , cord-015369-72cjogxz 6872 2 , , , cord-015369-72cjogxz 6872 3 Omphalozele Omphalozele NNP cord-015369-72cjogxz 6872 4 ' ' '' cord-015369-72cjogxz 6872 5 ' ' '' cord-015369-72cjogxz 6872 6 und und RB cord-015369-72cjogxz 6872 7 , , , cord-015369-72cjogxz 6872 8 , , , cord-015369-72cjogxz 6872 9 Ö Ö NNP cord-015369-72cjogxz 6872 10 sophagusatresie sophagusatresie NN cord-015369-72cjogxz 6872 11 ' ' '' cord-015369-72cjogxz 6872 12 ' ' `` cord-015369-72cjogxz 6872 13 sind sind UH cord-015369-72cjogxz 6872 14 als als NN cord-015369-72cjogxz 6873 1 Einzelfehlbildungen Einzelfehlbildungen NNP cord-015369-72cjogxz 6873 2 häufig häufig NNP cord-015369-72cjogxz 6873 3 mit mit NNP cord-015369-72cjogxz 6873 4 zusätzlichen zusätzlichen NNP cord-015369-72cjogxz 6873 5 Malformationen Malformationen NNP cord-015369-72cjogxz 6873 6 vergesellschaftet vergesellschaftet NNP cord-015369-72cjogxz 6873 7 . . . cord-015369-72cjogxz 6874 1 Ä Ä NNP cord-015369-72cjogxz 6874 2 ußerst ußerst NNP cord-015369-72cjogxz 6874 3 selten selten NNP cord-015369-72cjogxz 6874 4 ist ist FW cord-015369-72cjogxz 6874 5 das das NNP cord-015369-72cjogxz 6874 6 gleichzeitige gleichzeitige NNP cord-015369-72cjogxz 6874 7 Vorkommen Vorkommen NNP cord-015369-72cjogxz 6874 8 von von NNP cord-015369-72cjogxz 6874 9 Omphalozele Omphalozele NNP cord-015369-72cjogxz 6874 10 und und IN cord-015369-72cjogxz 6874 11 Ö Ö NNP cord-015369-72cjogxz 6874 12 sophagusatresie sophagusatresie NN cord-015369-72cjogxz 6874 13 , , , cord-015369-72cjogxz 6874 14 in in IN cord-015369-72cjogxz 6874 15 der der NNP cord-015369-72cjogxz 6874 16 internationalen internationalen NNP cord-015369-72cjogxz 6874 17 Literatur Literatur NNP cord-015369-72cjogxz 6874 18 sind sind NNP cord-015369-72cjogxz 6874 19 nur nur NNP cord-015369-72cjogxz 6874 20 einige einige NNP cord-015369-72cjogxz 6874 21 wenige wenige NNP cord-015369-72cjogxz 6874 22 Fallberichte Fallberichte NNP cord-015369-72cjogxz 6874 23 zu zu IN cord-015369-72cjogxz 6874 24 finden finden NNP cord-015369-72cjogxz 6874 25 . . . cord-015369-72cjogxz 6875 1 Methodik Methodik NNP cord-015369-72cjogxz 6875 2 . . . cord-015369-72cjogxz 6876 1 Bei Bei NNP cord-015369-72cjogxz 6876 2 einem einem NNP cord-015369-72cjogxz 6876 3 Feten Feten NNP cord-015369-72cjogxz 6876 4 wurde wurde NN cord-015369-72cjogxz 6876 5 sonographisch sonographisch NNP cord-015369-72cjogxz 6876 6 in in IN cord-015369-72cjogxz 6876 7 der der NNP cord-015369-72cjogxz 6876 8 14 14 CD cord-015369-72cjogxz 6876 9 . . . cord-015369-72cjogxz 6877 1 SSW SSW NNP cord-015369-72cjogxz 6877 2 eine eine NNP cord-015369-72cjogxz 6877 3 Omphalozele Omphalozele NNP cord-015369-72cjogxz 6877 4 diagnostiziert diagnostiziert NNP cord-015369-72cjogxz 6877 5 . . . cord-015369-72cjogxz 6878 1 Die die VB cord-015369-72cjogxz 6878 2 Chromosomenanalyse Chromosomenanalyse NNP cord-015369-72cjogxz 6878 3 ( ( -LRB- cord-015369-72cjogxz 6878 4 normaler normaler JJ cord-015369-72cjogxz 6878 5 weiblicher weiblicher JJ cord-015369-72cjogxz 6878 6 Karyotyp Karyotyp NNP cord-015369-72cjogxz 6878 7 ) ) -RRB- cord-015369-72cjogxz 6878 8 war war NN cord-015369-72cjogxz 6878 9 unauffällig unauffällig NN cord-015369-72cjogxz 6878 10 . . . cord-015369-72cjogxz 6879 1 Das Das NNP cord-015369-72cjogxz 6879 2 Organscreening Organscreening NNP cord-015369-72cjogxz 6879 3 und und TO cord-015369-72cjogxz 6879 4 die die VBP cord-015369-72cjogxz 6879 5 Verlaufskontrollen Verlaufskontrollen NNP cord-015369-72cjogxz 6879 6 ergaben ergaben NN cord-015369-72cjogxz 6879 7 keinen keinen NNP cord-015369-72cjogxz 6879 8 Hinweis Hinweis NNP cord-015369-72cjogxz 6879 9 auf auf NNP cord-015369-72cjogxz 6879 10 assoziierte assoziierte NN cord-015369-72cjogxz 6879 11 Fehlbildungen Fehlbildungen NNP cord-015369-72cjogxz 6879 12 . . . cord-015369-72cjogxz 6880 1 Bei Bei NNP cord-015369-72cjogxz 6880 2 der der NNP cord-015369-72cjogxz 6880 3 postpartalen postpartalen NN cord-015369-72cjogxz 6880 4 Untersuchung Untersuchung NNP cord-015369-72cjogxz 6880 5 des des NNP cord-015369-72cjogxz 6880 6 Neugeborenen Neugeborenen NNP cord-015369-72cjogxz 6880 7 war war NN cord-015369-72cjogxz 6880 8 , , , cord-015369-72cjogxz 6881 1 abgesehen abgesehen NNP cord-015369-72cjogxz 6881 2 von von NNP cord-015369-72cjogxz 6881 3 der der NNP cord-015369-72cjogxz 6881 4 Omphalozele Omphalozele NNP cord-015369-72cjogxz 6881 5 und und XX cord-015369-72cjogxz 6882 1 einem einem NNP cord-015369-72cjogxz 6882 2 Präaurikuläranhang Präaurikuläranhang NNP cord-015369-72cjogxz 6882 3 rechts rechts NNP cord-015369-72cjogxz 6882 4 , , , cord-015369-72cjogxz 6882 5 klinisch klinisch NNP cord-015369-72cjogxz 6882 6 und und NNP cord-015369-72cjogxz 6882 7 bildgebend bildgebend NNP cord-015369-72cjogxz 6882 8 keine keine NNP cord-015369-72cjogxz 6882 9 zusätzliche zusätzliche NNP cord-015369-72cjogxz 6882 10 Malformation Malformation NNP cord-015369-72cjogxz 6882 11 festzustellen festzustellen NN cord-015369-72cjogxz 6882 12 . . . cord-015369-72cjogxz 6883 1 Während Während NNP cord-015369-72cjogxz 6883 2 der der NNP cord-015369-72cjogxz 6883 3 Bauchwanddefektkorrektur Bauchwanddefektkorrektur NNP cord-015369-72cjogxz 6883 4 kam kam NNP cord-015369-72cjogxz 6883 5 es es XX cord-015369-72cjogxz 6883 6 plötzlich plötzlich NNP cord-015369-72cjogxz 6883 7 zu zu NNP cord-015369-72cjogxz 6883 8 Beatmungsproblemen Beatmungsproblemen NNP cord-015369-72cjogxz 6883 9 , , , cord-015369-72cjogxz 6883 10 zurückzuführen zurückzuführen NNP cord-015369-72cjogxz 6883 11 auf auf NNP cord-015369-72cjogxz 6884 1 eine eine NNP cord-015369-72cjogxz 6884 2 Ö Ö NNP cord-015369-72cjogxz 6884 3 sophagusatresie sophagusatresie NN cord-015369-72cjogxz 6884 4 Typ Typ NNP cord-015369-72cjogxz 6884 5 III III NNP cord-015369-72cjogxz 6884 6 b b NNP cord-015369-72cjogxz 6884 7 nach nach NNP cord-015369-72cjogxz 6884 8 Vogt Vogt NNP cord-015369-72cjogxz 6884 9 . . . cord-015369-72cjogxz 6885 1 Nach Nach NNP cord-015369-72cjogxz 6885 2 Anlage Anlage NNP cord-015369-72cjogxz 6885 3 einer einer NNP cord-015369-72cjogxz 6885 4 , , , cord-015369-72cjogxz 6886 1 , , , cord-015369-72cjogxz 6886 2 Schusterplastik Schusterplastik NNP cord-015369-72cjogxz 6886 3 ' ' POS cord-015369-72cjogxz 6886 4 ' ' '' cord-015369-72cjogxz 6886 5 wurde wurde NNP cord-015369-72cjogxz 6886 6 die die VB cord-015369-72cjogxz 6886 7 tracheoösophageale tracheoösophageale NNP cord-015369-72cjogxz 6887 1 Fistel Fistel NNP cord-015369-72cjogxz 6887 2 durchtrennt durchtrennt NN cord-015369-72cjogxz 6887 3 und und NNP cord-015369-72cjogxz 6887 4 , , , cord-015369-72cjogxz 6887 5 da da NNP cord-015369-72cjogxz 6887 6 das das NNP cord-015369-72cjogxz 6887 7 Kind Kind NNP cord-015369-72cjogxz 6887 8 stabil stabil NNP cord-015369-72cjogxz 6887 9 blieb blieb NNP cord-015369-72cjogxz 6887 10 , , , cord-015369-72cjogxz 6887 11 eine eine NNP cord-015369-72cjogxz 6887 12 Endzu Endzu NNP cord-015369-72cjogxz 6887 13 - - HYPH cord-015369-72cjogxz 6887 14 End End NNP cord-015369-72cjogxz 6887 15 - - HYPH cord-015369-72cjogxz 6887 16 Ö Ö NNP cord-015369-72cjogxz 6887 17 sophago sophago NN cord-015369-72cjogxz 6887 18 - - HYPH cord-015369-72cjogxz 6887 19 Ö Ö NNP cord-015369-72cjogxz 6887 20 sophagostomie sophagostomie NNP cord-015369-72cjogxz 6887 21 angeschlossen angeschlossen NNP cord-015369-72cjogxz 6887 22 . . . cord-015369-72cjogxz 6888 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6888 2 . . . cord-015369-72cjogxz 6889 1 Der Der NNP cord-015369-72cjogxz 6889 2 postoperative postoperative JJ cord-015369-72cjogxz 6889 3 Verlauf Verlauf NNP cord-015369-72cjogxz 6889 4 gestaltete gestaltete NNP cord-015369-72cjogxz 6889 5 sich sich NNP cord-015369-72cjogxz 6889 6 , , , cord-015369-72cjogxz 6889 7 abgesehen abgesehen NNP cord-015369-72cjogxz 6889 8 von von NNP cord-015369-72cjogxz 6889 9 einer einer NNP cord-015369-72cjogxz 6889 10 sich sich NNP cord-015369-72cjogxz 6889 11 spontan spontan NNP cord-015369-72cjogxz 6889 12 schließenden schließenden NNP cord-015369-72cjogxz 6889 13 Leckage Leckage NNP cord-015369-72cjogxz 6889 14 der der NNP cord-015369-72cjogxz 6889 15 Ö Ö NNP cord-015369-72cjogxz 6889 16 sophagusanastomose sophagusanastomose NN cord-015369-72cjogxz 6889 17 , , , cord-015369-72cjogxz 6889 18 komplikationslos komplikationslos NNP cord-015369-72cjogxz 6889 19 . . . cord-015369-72cjogxz 6890 1 Drei Drei NNP cord-015369-72cjogxz 6890 2 zusätzlich zusätzlich NNP cord-015369-72cjogxz 6890 3 diagnostizierte diagnostizierte NNS cord-015369-72cjogxz 6890 4 kleine kleine NNP cord-015369-72cjogxz 6890 5 Ventrikelseptumdefekte Ventrikelseptumdefekte NNP cord-015369-72cjogxz 6890 6 blieben blieben VBD cord-015369-72cjogxz 6890 7 asymptomatisch asymptomatisch NN cord-015369-72cjogxz 6890 8 . . . cord-015369-72cjogxz 6891 1 Das Das NNP cord-015369-72cjogxz 6891 2 Kind Kind NNP cord-015369-72cjogxz 6891 3 entwickelte entwickelte NNP cord-015369-72cjogxz 6891 4 sich sich NNP cord-015369-72cjogxz 6891 5 in in IN cord-015369-72cjogxz 6891 6 der der NNP cord-015369-72cjogxz 6891 7 Folge Folge NNP cord-015369-72cjogxz 6891 8 aufgrund aufgrund NNP cord-015369-72cjogxz 6891 9 einer einer NNP cord-015369-72cjogxz 6891 10 schweren schweren NNP cord-015369-72cjogxz 6891 11 Schluckstörung Schluckstörung NNP cord-015369-72cjogxz 6891 12 allerdings allerdings NNP cord-015369-72cjogxz 6891 13 nur nur NNP cord-015369-72cjogxz 6891 14 bescheiden bescheiden NNP cord-015369-72cjogxz 6891 15 . . . cord-015369-72cjogxz 6892 1 Diskussion Diskussion NNP cord-015369-72cjogxz 6892 2 . . . cord-015369-72cjogxz 6893 1 Die die VB cord-015369-72cjogxz 6893 2 intrauterine intrauterine JJ cord-015369-72cjogxz 6893 3 Realisierung Realisierung NNP cord-015369-72cjogxz 6893 4 von von NNP cord-015369-72cjogxz 6893 5 Mehrfachfehlbildungen Mehrfachfehlbildungen NNP cord-015369-72cjogxz 6893 6 ist ist NNP cord-015369-72cjogxz 6893 7 schwierig schwierig NN cord-015369-72cjogxz 6893 8 . . . cord-015369-72cjogxz 6894 1 Aber Aber NNP cord-015369-72cjogxz 6894 2 auch auch NNP cord-015369-72cjogxz 6894 3 postpartal postpartal NNP cord-015369-72cjogxz 6894 4 gelingt gelingt NNP cord-015369-72cjogxz 6894 5 der der NNP cord-015369-72cjogxz 6894 6 Nachweis Nachweis NNP cord-015369-72cjogxz 6894 7 einer einer NNP cord-015369-72cjogxz 6894 8 Fehlbildungskombination fehlbildungskombination NN cord-015369-72cjogxz 6894 9 nicht nicht NN cord-015369-72cjogxz 6894 10 immer immer NNP cord-015369-72cjogxz 6894 11 . . . cord-015369-72cjogxz 6895 1 I -PRON- PRP cord-015369-72cjogxz 6895 2 m be VBP cord-015369-72cjogxz 6896 1 seltenen seltenen NNP cord-015369-72cjogxz 6896 2 Fall Fall NNP cord-015369-72cjogxz 6896 3 kann kann NNP cord-015369-72cjogxz 6896 4 eine eine NNP cord-015369-72cjogxz 6896 5 gravierende gravierende NNP cord-015369-72cjogxz 6896 6 Fehlbildung Fehlbildung NNP cord-015369-72cjogxz 6896 7 gleichzeitig gleichzeitig NNP cord-015369-72cjogxz 6896 8 mit mit NNP cord-015369-72cjogxz 6896 9 einer einer NNP cord-015369-72cjogxz 6896 10 zweiten zweiten NNP cord-015369-72cjogxz 6896 11 korrekturbedü korrekturbedü NNP cord-015369-72cjogxz 6896 12 rftigen rftigen NNP cord-015369-72cjogxz 6896 13 , , , cord-015369-72cjogxz 6897 1 u. u. NNP cord-015369-72cjogxz 6898 1 U. U. NNP cord-015369-72cjogxz 6898 2 erst erst NNP cord-015369-72cjogxz 6898 3 intraoperativ intraoperativ JJ cord-015369-72cjogxz 6898 4 verifizierbaren verifizierbaren NNP cord-015369-72cjogxz 6898 5 Anomalie Anomalie NNP cord-015369-72cjogxz 6898 6 vorkommen vorkomman NNS cord-015369-72cjogxz 6898 7 . . . cord-015369-72cjogxz 6899 1 Die die VB cord-015369-72cjogxz 6899 2 Kombination Kombination NNP cord-015369-72cjogxz 6899 3 von von NNP cord-015369-72cjogxz 6899 4 Omphalozele Omphalozele NNP cord-015369-72cjogxz 6899 5 und und IN cord-015369-72cjogxz 6899 6 Ö Ö NNP cord-015369-72cjogxz 6899 7 sophagusatresie sophagusatresie NN cord-015369-72cjogxz 6899 8 , , , cord-015369-72cjogxz 6900 1 einhergehend einhergehend NNP cord-015369-72cjogxz 6900 2 mit mit NNP cord-015369-72cjogxz 6900 3 Ventrikelseptumdefekten Ventrikelseptumdefekten NNP cord-015369-72cjogxz 6900 4 und und IN cord-015369-72cjogxz 6900 5 einem einem NNP cord-015369-72cjogxz 6900 6 Präaurikuläranhang Präaurikuläranhang NNP cord-015369-72cjogxz 6900 7 , , , cord-015369-72cjogxz 6900 8 ist ist NNP cord-015369-72cjogxz 6900 9 ungewöhnlich ungewöhnlich NNP cord-015369-72cjogxz 6900 10 und und IN cord-015369-72cjogxz 6900 11 konnte konnte NNP cord-015369-72cjogxz 6900 12 keiner keiner NNP cord-015369-72cjogxz 6900 13 / / SYM cord-015369-72cjogxz 6900 14 m m NNP cord-015369-72cjogxz 6900 15 der der NN cord-015369-72cjogxz 6900 16 in in IN cord-015369-72cjogxz 6900 17 Frage Frage NNP cord-015369-72cjogxz 6900 18 kommenden kommenden JJ cord-015369-72cjogxz 6901 1 Fehlbildungsassoziationen/-syndrome Fehlbildungsassoziationen/-syndrome NNP cord-015369-72cjogxz 6902 1 ( ( -LRB- cord-015369-72cjogxz 6902 2 VACTERL VACTERL NNP cord-015369-72cjogxz 6902 3 - - HYPH cord-015369-72cjogxz 6902 4 Assoziation Assoziation NNP cord-015369-72cjogxz 6902 5 , , , cord-015369-72cjogxz 6902 6 CHARGE charge NN cord-015369-72cjogxz 6902 7 - - HYPH cord-015369-72cjogxz 6902 8 Syndrom Syndrom NNP cord-015369-72cjogxz 6902 9 , , , cord-015369-72cjogxz 6902 10 SCHISIS SCHISIS NNP cord-015369-72cjogxz 6902 11 - - HYPH cord-015369-72cjogxz 6902 12 Assoziation Assoziation NNP cord-015369-72cjogxz 6902 13 ) ) -RRB- cord-015369-72cjogxz 6903 1 zugeordnet zugeordnet NNP cord-015369-72cjogxz 6903 2 werden werden NNP cord-015369-72cjogxz 6903 3 . . . cord-015369-72cjogxz 6904 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6904 2 . . . cord-015369-72cjogxz 6905 1 Wenn Wenn NNP cord-015369-72cjogxz 6905 2 bei bei NNP cord-015369-72cjogxz 6905 3 einem einem NNP cord-015369-72cjogxz 6905 4 Neugeborenen Neugeborenen NNP cord-015369-72cjogxz 6905 5 eine eine NNP cord-015369-72cjogxz 6905 6 komplexe komplexe NN cord-015369-72cjogxz 6905 7 Fehlbildungskombination Fehlbildungskombination NNP cord-015369-72cjogxz 6905 8 zu zu NNP cord-015369-72cjogxz 6905 9 keiner keiner NNP cord-015369-72cjogxz 6905 10 / / SYM cord-015369-72cjogxz 6905 11 m m NN cord-015369-72cjogxz 6905 12 Assoziation/ Assoziation/ NNP cord-015369-72cjogxz 6905 13 Syndrom Syndrom NNP cord-015369-72cjogxz 6905 14 , , , cord-015369-72cjogxz 6905 15 , , , cord-015369-72cjogxz 6905 16 paßt paßt FW cord-015369-72cjogxz 6905 17 ' ' POS cord-015369-72cjogxz 6905 18 ' ' '' cord-015369-72cjogxz 6905 19 , , , cord-015369-72cjogxz 6905 20 ist ist NNP cord-015369-72cjogxz 6905 21 die die VBP cord-015369-72cjogxz 6905 22 Prognoseeinschätzung Prognoseeinschätzung NNP cord-015369-72cjogxz 6905 23 in in IN cord-015369-72cjogxz 6905 24 Hinblick Hinblick NNP cord-015369-72cjogxz 6906 1 auf auf NNP cord-015369-72cjogxz 6906 2 Outcome Outcome NNP cord-015369-72cjogxz 6906 3 und und IN cord-015369-72cjogxz 6906 4 zukünftige zukünftige NNP cord-015369-72cjogxz 6906 5 Entwicklung Entwicklung NNP cord-015369-72cjogxz 6906 6 des des FW cord-015369-72cjogxz 6906 7 betroffenen betroffenen NNP cord-015369-72cjogxz 6906 8 Kindes Kindes NNP cord-015369-72cjogxz 6906 9 schwierig schwierig NNP cord-015369-72cjogxz 6906 10 . . . cord-015369-72cjogxz 6907 1 Background background NN cord-015369-72cjogxz 6907 2 . . . cord-015369-72cjogxz 6908 1 The the DT cord-015369-72cjogxz 6908 2 prognosis prognosis NN cord-015369-72cjogxz 6908 3 of of IN cord-015369-72cjogxz 6908 4 colorectal colorectal JJ cord-015369-72cjogxz 6908 5 cancer cancer NN cord-015369-72cjogxz 6908 6 is be VBZ cord-015369-72cjogxz 6908 7 primarily primarily RB cord-015369-72cjogxz 6908 8 determined determine VBN cord-015369-72cjogxz 6908 9 by by IN cord-015369-72cjogxz 6908 10 anatomic anatomic JJ cord-015369-72cjogxz 6908 11 extend extend NN cord-015369-72cjogxz 6908 12 of of IN cord-015369-72cjogxz 6908 13 disease disease NN cord-015369-72cjogxz 6908 14 and and CC cord-015369-72cjogxz 6908 15 by by IN cord-015369-72cjogxz 6908 16 amenability amenability NN cord-015369-72cjogxz 6908 17 to to IN cord-015369-72cjogxz 6908 18 radical radical JJ cord-015369-72cjogxz 6908 19 resection resection NN cord-015369-72cjogxz 6908 20 . . . cord-015369-72cjogxz 6909 1 Results result NNS cord-015369-72cjogxz 6909 2 of of IN cord-015369-72cjogxz 6909 3 treatment treatment NN cord-015369-72cjogxz 6909 4 in in IN cord-015369-72cjogxz 6909 5 patients patient NNS cord-015369-72cjogxz 6909 6 who who WP cord-015369-72cjogxz 6909 7 underwent undergo VBD cord-015369-72cjogxz 6909 8 resection resection NN cord-015369-72cjogxz 6909 9 for for IN cord-015369-72cjogxz 6909 10 colon colon NN cord-015369-72cjogxz 6909 11 and and CC cord-015369-72cjogxz 6909 12 rectal rectal JJ cord-015369-72cjogxz 6909 13 cancer cancer NN cord-015369-72cjogxz 6909 14 in in IN cord-015369-72cjogxz 6909 15 two two CD cord-015369-72cjogxz 6909 16 time time NN cord-015369-72cjogxz 6909 17 periods period NNS cord-015369-72cjogxz 6909 18 were be VBD cord-015369-72cjogxz 6909 19 compared compare VBN cord-015369-72cjogxz 6909 20 , , , cord-015369-72cjogxz 6909 21 before before IN cord-015369-72cjogxz 6909 22 and and CC cord-015369-72cjogxz 6909 23 after after IN cord-015369-72cjogxz 6909 24 introduction introduction NN cord-015369-72cjogxz 6909 25 of of IN cord-015369-72cjogxz 6909 26 multidisciplinary multidisciplinary JJ cord-015369-72cjogxz 6909 27 tumor tumor NN cord-015369-72cjogxz 6909 28 board board NN cord-015369-72cjogxz 6909 29 in in IN cord-015369-72cjogxz 6909 30 the the DT cord-015369-72cjogxz 6909 31 second second JJ cord-015369-72cjogxz 6909 32 period period NN cord-015369-72cjogxz 6909 33 . . . cord-015369-72cjogxz 6910 1 Methods method NNS cord-015369-72cjogxz 6910 2 . . . cord-015369-72cjogxz 6911 1 In in IN cord-015369-72cjogxz 6911 2 order order NN cord-015369-72cjogxz 6911 3 to to TO cord-015369-72cjogxz 6911 4 improve improve VB cord-015369-72cjogxz 6911 5 the the DT cord-015369-72cjogxz 6911 6 results result NNS cord-015369-72cjogxz 6911 7 of of IN cord-015369-72cjogxz 6911 8 colorectal colorectal JJ cord-015369-72cjogxz 6911 9 cancer cancer NN cord-015369-72cjogxz 6911 10 , , , cord-015369-72cjogxz 6911 11 a a DT cord-015369-72cjogxz 6911 12 multidisciplinary multidisciplinary JJ cord-015369-72cjogxz 6911 13 tumor tumor NN cord-015369-72cjogxz 6911 14 board board NN cord-015369-72cjogxz 6911 15 was be VBD cord-015369-72cjogxz 6911 16 set set VBN cord-015369-72cjogxz 6911 17 up up RP cord-015369-72cjogxz 6911 18 and and CC cord-015369-72cjogxz 6911 19 beside beside IN cord-015369-72cjogxz 6911 20 the the DT cord-015369-72cjogxz 6911 21 strict strict JJ cord-015369-72cjogxz 6911 22 adoption adoption NN cord-015369-72cjogxz 6911 23 of of IN cord-015369-72cjogxz 6911 24 TME TME NNP cord-015369-72cjogxz 6911 25 principles principle NNS cord-015369-72cjogxz 6911 26 , , , cord-015369-72cjogxz 6911 27 an an DT cord-015369-72cjogxz 6911 28 oncological oncological JJ cord-015369-72cjogxz 6911 29 treatment treatment NN cord-015369-72cjogxz 6911 30 has have VBZ cord-015369-72cjogxz 6911 31 been be VBN cord-015369-72cjogxz 6911 32 systematically systematically RB cord-015369-72cjogxz 6911 33 included include VBN cord-015369-72cjogxz 6911 34 in in IN cord-015369-72cjogxz 6911 35 the the DT cord-015369-72cjogxz 6911 36 management management NN cord-015369-72cjogxz 6911 37 . . . cord-015369-72cjogxz 6912 1 1478 1478 CD cord-015369-72cjogxz 6912 2 patients patient NNS cord-015369-72cjogxz 6912 3 with with IN cord-015369-72cjogxz 6912 4 colorectal colorectal JJ cord-015369-72cjogxz 6912 5 cancer cancer NN cord-015369-72cjogxz 6912 6 underwent undergo VBD cord-015369-72cjogxz 6912 7 a a DT cord-015369-72cjogxz 6912 8 potentially potentially RB cord-015369-72cjogxz 6912 9 curative curative JJ cord-015369-72cjogxz 6912 10 resection resection NN cord-015369-72cjogxz 6912 11 between between IN cord-015369-72cjogxz 6912 12 1991 1991 CD cord-015369-72cjogxz 6912 13 and and CC cord-015369-72cjogxz 6912 14 2000 2000 CD cord-015369-72cjogxz 6912 15 . . . cord-015369-72cjogxz 6913 1 Results result NNS cord-015369-72cjogxz 6913 2 were be VBD cord-015369-72cjogxz 6913 3 analyzed analyze VBN cord-015369-72cjogxz 6913 4 for for IN cord-015369-72cjogxz 6913 5 two two CD cord-015369-72cjogxz 6913 6 groups group NNS cord-015369-72cjogxz 6913 7 of of IN cord-015369-72cjogxz 6913 8 patients patient NNS cord-015369-72cjogxz 6913 9 given give VBN cord-015369-72cjogxz 6913 10 different different JJ cord-015369-72cjogxz 6913 11 diagnostic diagnostic JJ cord-015369-72cjogxz 6913 12 approach approach NN cord-015369-72cjogxz 6913 13 and and CC cord-015369-72cjogxz 6913 14 treatment treatment NN cord-015369-72cjogxz 6913 15 regimens regimen NNS cord-015369-72cjogxz 6913 16 during during IN cord-015369-72cjogxz 6913 17 two two CD cord-015369-72cjogxz 6913 18 consecutive consecutive JJ cord-015369-72cjogxz 6913 19 5year 5year CD cord-015369-72cjogxz 6913 20 periods period NNS cord-015369-72cjogxz 6913 21 . . . cord-015369-72cjogxz 6914 1 Results result NNS cord-015369-72cjogxz 6914 2 . . . cord-015369-72cjogxz 6915 1 The the DT cord-015369-72cjogxz 6915 2 5-year 5-year CD cord-015369-72cjogxz 6915 3 survival survival NN cord-015369-72cjogxz 6915 4 rate rate NN cord-015369-72cjogxz 6915 5 of of IN cord-015369-72cjogxz 6915 6 R0 R0 NNP cord-015369-72cjogxz 6915 7 resected resect VBD cord-015369-72cjogxz 6915 8 patients patient NNS cord-015369-72cjogxz 6915 9 with with IN cord-015369-72cjogxz 6915 10 colon colon NN cord-015369-72cjogxz 6915 11 cancer cancer NN cord-015369-72cjogxz 6915 12 stage stage NN cord-015369-72cjogxz 6915 13 I -PRON- PRP cord-015369-72cjogxz 6915 14 and and CC cord-015369-72cjogxz 6915 15 III III NNP cord-015369-72cjogxz 6915 16 in in IN cord-015369-72cjogxz 6915 17 the the DT cord-015369-72cjogxz 6915 18 period period NN cord-015369-72cjogxz 6915 19 1996 1996 CD cord-015369-72cjogxz 6915 20 - - SYM cord-015369-72cjogxz 6915 21 2000 2000 CD cord-015369-72cjogxz 6915 22 was be VBD cord-015369-72cjogxz 6915 23 significantly significantly RB cord-015369-72cjogxz 6915 24 higher high JJR cord-015369-72cjogxz 6915 25 than than IN cord-015369-72cjogxz 6915 26 of of IN cord-015369-72cjogxz 6915 27 patients patient NNS cord-015369-72cjogxz 6915 28 operated operate VBN cord-015369-72cjogxz 6915 29 on on IN cord-015369-72cjogxz 6915 30 between between IN cord-015369-72cjogxz 6915 31 1991 1991 CD cord-015369-72cjogxz 6915 32 and and CC cord-015369-72cjogxz 6915 33 1995 1995 CD cord-015369-72cjogxz 6916 1 ( ( -LRB- cord-015369-72cjogxz 6916 2 stage stage NN cord-015369-72cjogxz 6916 3 I -PRON- PRP cord-015369-72cjogxz 6916 4 : : : cord-015369-72cjogxz 6916 5 86 86 CD cord-015369-72cjogxz 6916 6 % % NN cord-015369-72cjogxz 6916 7 vs. vs. CC cord-015369-72cjogxz 6916 8 70 70 CD cord-015369-72cjogxz 6916 9 % % NN cord-015369-72cjogxz 6916 10 ; ; , cord-015369-72cjogxz 6916 11 stage stage NN cord-015369-72cjogxz 6916 12 III III NNP cord-015369-72cjogxz 6916 13 : : : cord-015369-72cjogxz 6916 14 58 58 CD cord-015369-72cjogxz 6916 15 % % NN cord-015369-72cjogxz 6916 16 vs. vs. IN cord-015369-72cjogxz 6916 17 40 40 CD cord-015369-72cjogxz 6916 18 % % NN cord-015369-72cjogxz 6916 19 ) ) -RRB- cord-015369-72cjogxz 6916 20 . . . cord-015369-72cjogxz 6917 1 Similarly similarly RB cord-015369-72cjogxz 6917 2 , , , cord-015369-72cjogxz 6917 3 the the DT cord-015369-72cjogxz 6917 4 5-year 5-year CD cord-015369-72cjogxz 6917 5 survival survival NN cord-015369-72cjogxz 6917 6 rate rate NN cord-015369-72cjogxz 6917 7 for for IN cord-015369-72cjogxz 6917 8 R0 R0 NNP cord-015369-72cjogxz 6917 9 resected resect VBD cord-015369-72cjogxz 6917 10 patients patient NNS cord-015369-72cjogxz 6917 11 with with IN cord-015369-72cjogxz 6917 12 stage stage NN cord-015369-72cjogxz 6917 13 III iii CD cord-015369-72cjogxz 6917 14 rectal rectal JJ cord-015369-72cjogxz 6917 15 cancer cancer NN cord-015369-72cjogxz 6917 16 between between IN cord-015369-72cjogxz 6917 17 1996 1996 CD cord-015369-72cjogxz 6917 18 and and CC cord-015369-72cjogxz 6917 19 2000 2000 CD cord-015369-72cjogxz 6917 20 was be VBD cord-015369-72cjogxz 6917 21 significantly significantly RB cord-015369-72cjogxz 6917 22 better well JJR cord-015369-72cjogxz 6917 23 than than IN cord-015369-72cjogxz 6917 24 that that DT cord-015369-72cjogxz 6917 25 for for IN cord-015369-72cjogxz 6917 26 patients patient NNS cord-015369-72cjogxz 6917 27 operated operate VBN cord-015369-72cjogxz 6917 28 on on IN cord-015369-72cjogxz 6917 29 during during IN cord-015369-72cjogxz 6917 30 the the DT cord-015369-72cjogxz 6917 31 early early JJ cord-015369-72cjogxz 6917 32 period period NN cord-015369-72cjogxz 6917 33 ( ( -LRB- cord-015369-72cjogxz 6917 34 58 58 CD cord-015369-72cjogxz 6917 35 % % NN cord-015369-72cjogxz 6917 36 vs. vs. FW cord-015369-72cjogxz 6917 37 31%).Conclusions 31%).conclusion NNS cord-015369-72cjogxz 6917 38 . . . cord-015369-72cjogxz 6918 1 Patients patient NNS cord-015369-72cjogxz 6918 2 who who WP cord-015369-72cjogxz 6918 3 underwent undergo VBD cord-015369-72cjogxz 6918 4 R0 R0 NNP cord-015369-72cjogxz 6918 5 resection resection NN cord-015369-72cjogxz 6918 6 for for IN cord-015369-72cjogxz 6918 7 colon colon NN cord-015369-72cjogxz 6918 8 and and CC cord-015369-72cjogxz 6918 9 rectal rectal JJ cord-015369-72cjogxz 6918 10 cancer cancer NN cord-015369-72cjogxz 6918 11 during during IN cord-015369-72cjogxz 6918 12 the the DT cord-015369-72cjogxz 6918 13 period period NN cord-015369-72cjogxz 6918 14 1995 1995 CD cord-015369-72cjogxz 6918 15 - - SYM cord-015369-72cjogxz 6918 16 2000 2000 CD cord-015369-72cjogxz 6918 17 showed show VBD cord-015369-72cjogxz 6918 18 a a DT cord-015369-72cjogxz 6918 19 significantly significantly RB cord-015369-72cjogxz 6918 20 improved improve VBN cord-015369-72cjogxz 6918 21 5-year 5-year CD cord-015369-72cjogxz 6918 22 survival survival NN cord-015369-72cjogxz 6918 23 rate rate NN cord-015369-72cjogxz 6918 24 compared compare VBN cord-015369-72cjogxz 6918 25 to to IN cord-015369-72cjogxz 6918 26 those those DT cord-015369-72cjogxz 6918 27 operated operate VBN cord-015369-72cjogxz 6918 28 on on IN cord-015369-72cjogxz 6918 29 between between IN cord-015369-72cjogxz 6918 30 1991 1991 CD cord-015369-72cjogxz 6918 31 and and CC cord-015369-72cjogxz 6918 32 1995 1995 CD cord-015369-72cjogxz 6918 33 . . . cord-015369-72cjogxz 6919 1 Improved improve VBN cord-015369-72cjogxz 6919 2 survival survival NN cord-015369-72cjogxz 6919 3 in in IN cord-015369-72cjogxz 6919 4 these these DT cord-015369-72cjogxz 6919 5 patients patient NNS cord-015369-72cjogxz 6919 6 is be VBZ cord-015369-72cjogxz 6919 7 to to IN cord-015369-72cjogxz 6919 8 a a DT cord-015369-72cjogxz 6919 9 great great JJ cord-015369-72cjogxz 6919 10 extent extent NN cord-015369-72cjogxz 6919 11 attributable attributable JJ cord-015369-72cjogxz 6919 12 to to IN cord-015369-72cjogxz 6919 13 improvements improvement NNS cord-015369-72cjogxz 6919 14 in in IN cord-015369-72cjogxz 6919 15 clinical clinical JJ cord-015369-72cjogxz 6919 16 practice practice NN cord-015369-72cjogxz 6919 17 combining combine VBG cord-015369-72cjogxz 6919 18 surgery surgery NN cord-015369-72cjogxz 6919 19 with with IN cord-015369-72cjogxz 6919 20 other other JJ cord-015369-72cjogxz 6919 21 modalities modality NNS cord-015369-72cjogxz 6919 22 of of IN cord-015369-72cjogxz 6919 23 treatment treatment NN cord-015369-72cjogxz 6919 24 . . . cord-015369-72cjogxz 6920 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6920 2 . . . cord-015369-72cjogxz 6921 1 Trotz Trotz NNP cord-015369-72cjogxz 6921 2 der der NNP cord-015369-72cjogxz 6922 1 oft oft RB cord-015369-72cjogxz 6922 2 schwerwiegenden schwerwiegenden NNP cord-015369-72cjogxz 6922 3 Grunderkrankung Grunderkrankung NNP cord-015369-72cjogxz 6922 4 der der NNP cord-015369-72cjogxz 6922 5 Patienten Patienten NNP cord-015369-72cjogxz 6922 6 und und XX cord-015369-72cjogxz 6923 1 dem dem NNP cord-015369-72cjogxz 6923 2 aggressiven aggressiven NNP cord-015369-72cjogxz 6923 3 Infektionsmuster Infektionsmuster NNP cord-015369-72cjogxz 6923 4 der der NNP cord-015369-72cjogxz 6923 5 Zygomycosen Zygomycosen NNP cord-015369-72cjogxz 6924 1 und und NNP cord-015369-72cjogxz 6924 2 der der NNP cord-015369-72cjogxz 6924 3 daraus daraus NNP cord-015369-72cjogxz 6925 1 resultierenden resultierenden NNP cord-015369-72cjogxz 6925 2 schlechten schlechten NNP cord-015369-72cjogxz 6925 3 Prognose Prognose NNP cord-015369-72cjogxz 6925 4 kann kann NNP cord-015369-72cjogxz 6925 5 eine eine NNP cord-015369-72cjogxz 6926 1 solche solche NNP cord-015369-72cjogxz 6926 2 Infektion Infektion NNP cord-015369-72cjogxz 6926 3 bei bei NNP cord-015369-72cjogxz 6926 4 chirurgischen chirurgischen NNP cord-015369-72cjogxz 6927 1 Handeln Handeln NNP cord-015369-72cjogxz 6927 2 gepaart gepaart NNP cord-015369-72cjogxz 6927 3 mit mit NNP cord-015369-72cjogxz 6927 4 einer einer NNP cord-015369-72cjogxz 6927 5 optimalen optimalen NNP cord-015369-72cjogxz 6927 6 antimykotischen antimykotischen NNP cord-015369-72cjogxz 6927 7 und und NNP cord-015369-72cjogxz 6928 1 intensivmedizinischen intensivmedizinischen NNP cord-015369-72cjogxz 6928 2 Therapie Therapie NNP cord-015369-72cjogxz 6928 3 überlebt überlebt NNP cord-015369-72cjogxz 6928 4 werden werden NNP cord-015369-72cjogxz 6928 5 . . . cord-015369-72cjogxz 6929 1 Context context NN cord-015369-72cjogxz 6929 2 . . . cord-015369-72cjogxz 6930 1 Adipose adipose JJ cord-015369-72cjogxz 6930 2 tissue tissue NN cord-015369-72cjogxz 6930 3 ( ( -LRB- cord-015369-72cjogxz 6930 4 AT at NN cord-015369-72cjogxz 6930 5 ) ) -RRB- cord-015369-72cjogxz 6930 6 macrophages macrophage NNS cord-015369-72cjogxz 6930 7 are be VBP cord-015369-72cjogxz 6930 8 key key JJ cord-015369-72cjogxz 6930 9 suspects suspect NNS cord-015369-72cjogxz 6930 10 to to TO cord-015369-72cjogxz 6930 11 cause cause VB cord-015369-72cjogxz 6930 12 obesity obesity NN cord-015369-72cjogxz 6930 13 - - HYPH cord-015369-72cjogxz 6930 14 associated associate VBN cord-015369-72cjogxz 6930 15 insulin insulin NN cord-015369-72cjogxz 6930 16 resistance resistance NN cord-015369-72cjogxz 6930 17 . . . cord-015369-72cjogxz 6931 1 Besides besides IN cord-015369-72cjogxz 6931 2 inflammatory inflammatory JJ cord-015369-72cjogxz 6931 3 mediators mediator NNS cord-015369-72cjogxz 6931 4 promoting promote VBG cord-015369-72cjogxz 6931 5 insulin insulin NN cord-015369-72cjogxz 6931 6 resistance resistance NN cord-015369-72cjogxz 6931 7 , , , cord-015369-72cjogxz 6931 8 AT at IN cord-015369-72cjogxz 6931 9 macrophages macrophage NNS cord-015369-72cjogxz 6931 10 express express VBP cord-015369-72cjogxz 6931 11 the the DT cord-015369-72cjogxz 6931 12 hemoglobin hemoglobin NN cord-015369-72cjogxz 6931 13 scavenger scavenger NN cord-015369-72cjogxz 6931 14 receptor receptor NN cord-015369-72cjogxz 6931 15 CD163 CD163 NNP cord-015369-72cjogxz 6931 16 and and CC cord-015369-72cjogxz 6931 17 the the DT cord-015369-72cjogxz 6931 18 downstream downstream JJ cord-015369-72cjogxz 6931 19 enzyme enzyme NN cord-015369-72cjogxz 6931 20 heme heme NN cord-015369-72cjogxz 6931 21 oxygenase-1 oxygenase-1 NNP cord-015369-72cjogxz 6931 22 ( ( -LRB- cord-015369-72cjogxz 6931 23 HO-1 HO-1 NNP cord-015369-72cjogxz 6931 24 ) ) -RRB- cord-015369-72cjogxz 6931 25 that that WDT cord-015369-72cjogxz 6931 26 protect protect VBP cord-015369-72cjogxz 6931 27 from from IN cord-015369-72cjogxz 6931 28 free free JJ cord-015369-72cjogxz 6931 29 hemoglobin hemoglobin NN cord-015369-72cjogxz 6931 30 - - HYPH cord-015369-72cjogxz 6931 31 induced induce VBN cord-015369-72cjogxz 6931 32 oxidative oxidative JJ cord-015369-72cjogxz 6931 33 stress stress NN cord-015369-72cjogxz 6931 34 and and CC cord-015369-72cjogxz 6931 35 metabolize metabolize VB cord-015369-72cjogxz 6931 36 hemoglobin hemoglobin NN cord-015369-72cjogxz 6931 37 to to IN cord-015369-72cjogxz 6931 38 anti anti JJ cord-015369-72cjogxz 6931 39 - - JJ cord-015369-72cjogxz 6931 40 inflammatory inflammatory JJ cord-015369-72cjogxz 6931 41 mediators mediator NNS cord-015369-72cjogxz 6931 42 , , , cord-015369-72cjogxz 6931 43 respectively respectively RB cord-015369-72cjogxz 6931 44 . . . cord-015369-72cjogxz 6932 1 Background background NN cord-015369-72cjogxz 6932 2 . . . cord-015369-72cjogxz 6933 1 Aim aim VB cord-015369-72cjogxz 6933 2 of of IN cord-015369-72cjogxz 6933 3 this this DT cord-015369-72cjogxz 6933 4 study study NN cord-015369-72cjogxz 6933 5 was be VBD cord-015369-72cjogxz 6933 6 to to TO cord-015369-72cjogxz 6933 7 evaluate evaluate VB cord-015369-72cjogxz 6933 8 the the DT cord-015369-72cjogxz 6933 9 association association NN cord-015369-72cjogxz 6933 10 of of IN cord-015369-72cjogxz 6933 11 CD163 CD163 NNP cord-015369-72cjogxz 6933 12 and and CC cord-015369-72cjogxz 6933 13 HO-1 HO-1 NNP cord-015369-72cjogxz 6933 14 expression expression NN cord-015369-72cjogxz 6933 15 in in IN cord-015369-72cjogxz 6933 16 visceral visceral JJ cord-015369-72cjogxz 6933 17 and and CC cord-015369-72cjogxz 6933 18 subcutaneous subcutaneous JJ cord-015369-72cjogxz 6933 19 AT at IN cord-015369-72cjogxz 6933 20 with with IN cord-015369-72cjogxz 6933 21 obesity obesity NN cord-015369-72cjogxz 6933 22 , , , cord-015369-72cjogxz 6933 23 metabolic metabolic JJ cord-015369-72cjogxz 6933 24 parameters parameter NNS cord-015369-72cjogxz 6933 25 , , , cord-015369-72cjogxz 6933 26 body body NN cord-015369-72cjogxz 6933 27 fat fat NN cord-015369-72cjogxz 6933 28 distribution distribution NN cord-015369-72cjogxz 6933 29 , , , cord-015369-72cjogxz 6933 30 and and CC cord-015369-72cjogxz 6933 31 AT at IN cord-015369-72cjogxz 6933 32 inflammation inflammation NN cord-015369-72cjogxz 6933 33 . . . cord-015369-72cjogxz 6934 1 Methods method NNS cord-015369-72cjogxz 6934 2 . . . cord-015369-72cjogxz 6935 1 Morbidly morbidly RB cord-015369-72cjogxz 6935 2 obese obese JJ cord-015369-72cjogxz 6935 3 patients patient NNS cord-015369-72cjogxz 6935 4 ( ( -LRB- cord-015369-72cjogxz 6935 5 BMI BMI NNP cord-015369-72cjogxz 6935 6 > > XX cord-015369-72cjogxz 6935 7 40 40 CD cord-015369-72cjogxz 6935 8 kg kg NN cord-015369-72cjogxz 6935 9 / / SYM cord-015369-72cjogxz 6935 10 m m NN cord-015369-72cjogxz 6935 11 2 2 CD cord-015369-72cjogxz 6935 12 ) ) -RRB- cord-015369-72cjogxz 6935 13 who who WP cord-015369-72cjogxz 6935 14 underwent undergo VBD cord-015369-72cjogxz 6935 15 laparoscopic laparoscopic JJ cord-015369-72cjogxz 6935 16 surgery surgery NN cord-015369-72cjogxz 6935 17 for for IN cord-015369-72cjogxz 6935 18 gastric gastric JJ cord-015369-72cjogxz 6935 19 banding banding NN cord-015369-72cjogxz 6935 20 ( ( -LRB- cord-015369-72cjogxz 6935 21 n n NN cord-015369-72cjogxz 6935 22 ¼ ¼ NNP cord-015369-72cjogxz 6935 23 20 20 CD cord-015369-72cjogxz 6935 24 ) ) -RRB- cord-015369-72cjogxz 6935 25 were be VBD cord-015369-72cjogxz 6935 26 matched match VBN cord-015369-72cjogxz 6935 27 for for IN cord-015369-72cjogxz 6935 28 age age NN cord-015369-72cjogxz 6935 29 and and CC cord-015369-72cjogxz 6935 30 sex sex NN cord-015369-72cjogxz 6935 31 to to TO cord-015369-72cjogxz 6935 32 lean lean VB cord-015369-72cjogxz 6935 33 control control NN cord-015369-72cjogxz 6935 34 subjects subject NNS cord-015369-72cjogxz 6935 35 ( ( -LRB- cord-015369-72cjogxz 6935 36 BMI BMI NNP cord-015369-72cjogxz 6935 37 < < XX cord-015369-72cjogxz 6935 38 30 30 CD cord-015369-72cjogxz 6935 39 kg kg NN cord-015369-72cjogxz 6935 40 / / SYM cord-015369-72cjogxz 6935 41 m m NN cord-015369-72cjogxz 6935 42 ; ; : cord-015369-72cjogxz 6935 43 n n NNP cord-015369-72cjogxz 6935 44 ¼ ¼ NNP cord-015369-72cjogxz 6935 45 20).Main 20).main CD cord-015369-72cjogxz 6935 46 outcome outcome NN cord-015369-72cjogxz 6935 47 measures measure NNS cord-015369-72cjogxz 6935 48 . . . cord-015369-72cjogxz 6936 1 CD163 CD163 NNP cord-015369-72cjogxz 6936 2 and and CC cord-015369-72cjogxz 6936 3 HO-1 HO-1 NNP cord-015369-72cjogxz 6936 4 as as RB cord-015369-72cjogxz 6936 5 well well RB cord-015369-72cjogxz 6936 6 as as IN cord-015369-72cjogxz 6936 7 the the DT cord-015369-72cjogxz 6936 8 macrophage macrophage NN cord-015369-72cjogxz 6936 9 marker marker NN cord-015369-72cjogxz 6936 10 CD68 CD68 NNP cord-015369-72cjogxz 6936 11 mRNA mrna NN cord-015369-72cjogxz 6936 12 expression expression NN cord-015369-72cjogxz 6936 13 was be VBD cord-015369-72cjogxz 6936 14 analyzed analyze VBN cord-015369-72cjogxz 6936 15 in in IN cord-015369-72cjogxz 6936 16 visceral visceral JJ cord-015369-72cjogxz 6936 17 ( ( -LRB- cord-015369-72cjogxz 6936 18 omental omental JJ cord-015369-72cjogxz 6936 19 ) ) -RRB- cord-015369-72cjogxz 6936 20 and and CC cord-015369-72cjogxz 6936 21 subcutaneous subcutaneous JJ cord-015369-72cjogxz 6936 22 AT AT NNP cord-015369-72cjogxz 6936 23 . . . cord-015369-72cjogxz 6937 1 Moreover moreover RB cord-015369-72cjogxz 6937 2 , , , cord-015369-72cjogxz 6937 3 serum serum NN cord-015369-72cjogxz 6937 4 concentration concentration NN cord-015369-72cjogxz 6937 5 of of IN cord-015369-72cjogxz 6937 6 soluble soluble JJ cord-015369-72cjogxz 6937 7 CD163 CD163 NNP cord-015369-72cjogxz 6937 8 was be VBD cord-015369-72cjogxz 6937 9 determined determine VBN cord-015369-72cjogxz 6937 10 by by IN cord-015369-72cjogxz 6937 11 ELISA.Results elisa.result NNS cord-015369-72cjogxz 6937 12 . . . cord-015369-72cjogxz 6938 1 CD163 CD163 NNP cord-015369-72cjogxz 6938 2 expression expression NN cord-015369-72cjogxz 6938 3 was be VBD cord-015369-72cjogxz 6938 4 highly highly RB cord-015369-72cjogxz 6938 5 upregulated upregulate VBN cord-015369-72cjogxz 6938 6 in in IN cord-015369-72cjogxz 6938 7 human human NN cord-015369-72cjogxz 6938 8 AT AT NNP cord-015369-72cjogxz 6938 9 and and CC cord-015369-72cjogxz 6938 10 soluble soluble JJ cord-015369-72cjogxz 6938 11 CD163 CD163 NNP cord-015369-72cjogxz 6938 12 serum serum NN cord-015369-72cjogxz 6938 13 concentration concentration NN cord-015369-72cjogxz 6938 14 was be VBD cord-015369-72cjogxz 6938 15 elevated elevate VBN cord-015369-72cjogxz 6938 16 in in IN cord-015369-72cjogxz 6938 17 obesity obesity NN cord-015369-72cjogxz 6938 18 . . . cord-015369-72cjogxz 6939 1 Also also RB cord-015369-72cjogxz 6939 2 HO-1 HO-1 NNP cord-015369-72cjogxz 6939 3 was be VBD cord-015369-72cjogxz 6939 4 upregulated upregulate VBN cord-015369-72cjogxz 6939 5 in in IN cord-015369-72cjogxz 6939 6 AT AT NNP cord-015369-72cjogxz 6939 7 and and CC cord-015369-72cjogxz 6939 8 expressed express VBD cord-015369-72cjogxz 6939 9 exclusively exclusively RB cord-015369-72cjogxz 6939 10 in in IN cord-015369-72cjogxz 6939 11 macrophages macrophage NNS cord-015369-72cjogxz 6939 12 . . . cord-015369-72cjogxz 6940 1 While while IN cord-015369-72cjogxz 6940 2 CD163 CD163 NNP cord-015369-72cjogxz 6940 3 expression expression NN cord-015369-72cjogxz 6940 4 strictly strictly RB cord-015369-72cjogxz 6940 5 correlated correlate VBD cord-015369-72cjogxz 6940 6 with with IN cord-015369-72cjogxz 6940 7 macrophage macrophage NN cord-015369-72cjogxz 6940 8 abundance abundance NN cord-015369-72cjogxz 6940 9 as as IN cord-015369-72cjogxz 6940 10 assessed assess VBN cord-015369-72cjogxz 6940 11 by by IN cord-015369-72cjogxz 6940 12 CD68 CD68 NNP cord-015369-72cjogxz 6940 13 expression expression NN cord-015369-72cjogxz 6940 14 , , , cord-015369-72cjogxz 6940 15 HO-1 HO-1 NNP cord-015369-72cjogxz 6940 16 upregulation upregulation NN cord-015369-72cjogxz 6940 17 by by IN cord-015369-72cjogxz 6940 18 obesity obesity NN cord-015369-72cjogxz 6940 19 exceeded exceed VBD cord-015369-72cjogxz 6940 20 the the DT cord-015369-72cjogxz 6940 21 increase increase NN cord-015369-72cjogxz 6940 22 of of IN cord-015369-72cjogxz 6940 23 CD68 CD68 NNP cord-015369-72cjogxz 6940 24 , , , cord-015369-72cjogxz 6940 25 indicating indicate VBG cord-015369-72cjogxz 6940 26 a a DT cord-015369-72cjogxz 6940 27 regulation regulation NN cord-015369-72cjogxz 6940 28 within within IN cord-015369-72cjogxz 6940 29 macrophages macrophage NNS cord-015369-72cjogxz 6940 30 . . . cord-015369-72cjogxz 6941 1 Strikingly strikingly RB cord-015369-72cjogxz 6941 2 , , , cord-015369-72cjogxz 6941 3 waist waist NN cord-015369-72cjogxz 6941 4 to to IN cord-015369-72cjogxz 6941 5 hip hip NN cord-015369-72cjogxz 6941 6 ratio ratio NN cord-015369-72cjogxz 6941 7 negatively negatively RB cord-015369-72cjogxz 6941 8 correlated correlate VBN cord-015369-72cjogxz 6941 9 with with IN cord-015369-72cjogxz 6941 10 relative relative JJ cord-015369-72cjogxz 6941 11 visceral visceral JJ cord-015369-72cjogxz 6941 12 expression expression NN cord-015369-72cjogxz 6941 13 of of IN cord-015369-72cjogxz 6941 14 HO-1 HO-1 NNP cord-015369-72cjogxz 6941 15 ( ( -LRB- cord-015369-72cjogxz 6941 16 p p NN cord-015369-72cjogxz 6941 17 ¼ ¼ CD cord-015369-72cjogxz 6941 18 0.009 0.009 CD cord-015369-72cjogxz 6941 19 ) ) -RRB- cord-015369-72cjogxz 6941 20 and and CC cord-015369-72cjogxz 6941 21 visceral visceral JJ cord-015369-72cjogxz 6941 22 HO-1 HO-1 NNP cord-015369-72cjogxz 6941 23 expression expression NN cord-015369-72cjogxz 6941 24 negatively negatively RB cord-015369-72cjogxz 6941 25 correlated correlate VBD cord-015369-72cjogxz 6941 26 with with IN cord-015369-72cjogxz 6941 27 HOMA HOMA NNP cord-015369-72cjogxz 6941 28 - - HYPH cord-015369-72cjogxz 6941 29 IR IR NNP cord-015369-72cjogxz 6941 30 ( ( -LRB- cord-015369-72cjogxz 6941 31 p p NN cord-015369-72cjogxz 6941 32 ¼ ¼ NNP cord-015369-72cjogxz 6941 33 0.024).Conclusions 0.024).conclusions CD cord-015369-72cjogxz 6941 34 . . . cord-015369-72cjogxz 6942 1 Visceral visceral JJ cord-015369-72cjogxz 6942 2 HO-1 HO-1 NNP cord-015369-72cjogxz 6942 3 expression expression NN cord-015369-72cjogxz 6942 4 is be VBZ cord-015369-72cjogxz 6942 5 determined determine VBN cord-015369-72cjogxz 6942 6 by by IN cord-015369-72cjogxz 6942 7 body body NN cord-015369-72cjogxz 6942 8 fat fat NN cord-015369-72cjogxz 6942 9 distribution distribution NN cord-015369-72cjogxz 6942 10 and and CC cord-015369-72cjogxz 6942 11 attenuates attenuate VBZ cord-015369-72cjogxz 6942 12 obesity obesity NN cord-015369-72cjogxz 6942 13 - - HYPH cord-015369-72cjogxz 6942 14 induced induce VBN cord-015369-72cjogxz 6942 15 insulin insulin NN cord-015369-72cjogxz 6942 16 resistance resistance NN cord-015369-72cjogxz 6942 17 . . . cord-015369-72cjogxz 6943 1 Do do VBP cord-015369-72cjogxz 6943 2 we -PRON- PRP cord-015369-72cjogxz 6943 3 need need VB cord-015369-72cjogxz 6943 4 to to TO cord-015369-72cjogxz 6943 5 substitute substitute VB cord-015369-72cjogxz 6943 6 Vitamin vitamin NN cord-015369-72cjogxz 6943 7 B12 B12 NNP cord-015369-72cjogxz 6943 8 parenterally parenterally NN cord-015369-72cjogxz 6943 9 after after IN cord-015369-72cjogxz 6943 10 gastric gastric JJ cord-015369-72cjogxz 6943 11 sleeve sleeve NN cord-015369-72cjogxz 6943 12 resection resection NN cord-015369-72cjogxz 6943 13 ? ? . cord-015369-72cjogxz 6944 1 Background background NN cord-015369-72cjogxz 6944 2 . . . cord-015369-72cjogxz 6945 1 Daily daily JJ cord-015369-72cjogxz 6945 2 oral oral JJ cord-015369-72cjogxz 6945 3 multivitamin multivitamin NN cord-015369-72cjogxz 6945 4 supplementation supplementation NN cord-015369-72cjogxz 6945 5 is be VBZ cord-015369-72cjogxz 6945 6 recommended recommend VBN cord-015369-72cjogxz 6945 7 for for IN cord-015369-72cjogxz 6945 8 patients patient NNS cord-015369-72cjogxz 6945 9 after after IN cord-015369-72cjogxz 6945 10 restrictive restrictive JJ cord-015369-72cjogxz 6945 11 bariatric bariatric JJ cord-015369-72cjogxz 6945 12 surgery surgery NN cord-015369-72cjogxz 6945 13 , , , cord-015369-72cjogxz 6945 14 whereas whereas IN cord-015369-72cjogxz 6945 15 after after IN cord-015369-72cjogxz 6945 16 malabsorptive malabsorptive JJ cord-015369-72cjogxz 6945 17 procedures procedure NNS cord-015369-72cjogxz 6945 18 or or CC cord-015369-72cjogxz 6945 19 major major JJ cord-015369-72cjogxz 6945 20 gastric gastric JJ cord-015369-72cjogxz 6945 21 resections resection NNS cord-015369-72cjogxz 6945 22 , , , cord-015369-72cjogxz 6945 23 parenteral parenteral JJ cord-015369-72cjogxz 6945 24 substitution substitution NN cord-015369-72cjogxz 6945 25 of of IN cord-015369-72cjogxz 6945 26 Vitamin vitamin NN cord-015369-72cjogxz 6945 27 B12 b12 NN cord-015369-72cjogxz 6945 28 ( ( -LRB- cord-015369-72cjogxz 6945 29 VitB12 VitB12 NNP cord-015369-72cjogxz 6945 30 ) ) -RRB- cord-015369-72cjogxz 6945 31 is be VBZ cord-015369-72cjogxz 6945 32 mandatory mandatory JJ cord-015369-72cjogxz 6945 33 . . . cord-015369-72cjogxz 6946 1 Sleeve sleeve NN cord-015369-72cjogxz 6946 2 gastrectomy gastrectomy NN cord-015369-72cjogxz 6946 3 ( ( -LRB- cord-015369-72cjogxz 6946 4 SG SG NNP cord-015369-72cjogxz 6946 5 ) ) -RRB- cord-015369-72cjogxz 6946 6 , , , cord-015369-72cjogxz 6946 7 a a DT cord-015369-72cjogxz 6946 8 mainly mainly RB cord-015369-72cjogxz 6946 9 restrictive restrictive JJ cord-015369-72cjogxz 6946 10 procedure procedure NN cord-015369-72cjogxz 6946 11 , , , cord-015369-72cjogxz 6946 12 has have VBZ cord-015369-72cjogxz 6946 13 been be VBN cord-015369-72cjogxz 6946 14 established establish VBN cord-015369-72cjogxz 6946 15 in in IN cord-015369-72cjogxz 6946 16 many many JJ cord-015369-72cjogxz 6946 17 bariatric bariatric JJ cord-015369-72cjogxz 6946 18 surgical surgical JJ cord-015369-72cjogxz 6946 19 centers center NNS cord-015369-72cjogxz 6946 20 in in IN cord-015369-72cjogxz 6946 21 the the DT cord-015369-72cjogxz 6946 22 last last JJ cord-015369-72cjogxz 6946 23 few few JJ cord-015369-72cjogxz 6946 24 years year NNS cord-015369-72cjogxz 6946 25 , , , cord-015369-72cjogxz 6946 26 either either CC cord-015369-72cjogxz 6946 27 as as IN cord-015369-72cjogxz 6946 28 a a DT cord-015369-72cjogxz 6946 29 definitive definitive JJ cord-015369-72cjogxz 6946 30 measure measure NN cord-015369-72cjogxz 6946 31 or or CC cord-015369-72cjogxz 6946 32 as as IN cord-015369-72cjogxz 6946 33 a a DT cord-015369-72cjogxz 6946 34 first first JJ cord-015369-72cjogxz 6946 35 step step NN cord-015369-72cjogxz 6946 36 before before IN cord-015369-72cjogxz 6946 37 major major JJ cord-015369-72cjogxz 6946 38 malabsorptive malabsorptive JJ cord-015369-72cjogxz 6946 39 procedures procedure NNS cord-015369-72cjogxz 6946 40 . . . cord-015369-72cjogxz 6947 1 The the DT cord-015369-72cjogxz 6947 2 resected resected JJ cord-015369-72cjogxz 6947 3 stomach stomach NN cord-015369-72cjogxz 6947 4 volume volume NN cord-015369-72cjogxz 6947 5 has have VBZ cord-015369-72cjogxz 6947 6 been be VBN cord-015369-72cjogxz 6947 7 reported report VBN cord-015369-72cjogxz 6947 8 between between IN cord-015369-72cjogxz 6947 9 700 700 CD cord-015369-72cjogxz 6947 10 and and CC cord-015369-72cjogxz 6947 11 1000 1000 CD cord-015369-72cjogxz 6947 12 mL. mL. NNS cord-015369-72cjogxz 6947 13 SG SG NNP cord-015369-72cjogxz 6947 14 therefore therefore RB cord-015369-72cjogxz 6947 15 amounts amount VBZ cord-015369-72cjogxz 6947 16 to to IN cord-015369-72cjogxz 6947 17 a a DT cord-015369-72cjogxz 6947 18 subtotal subtotal NN cord-015369-72cjogxz 6947 19 ( ( -LRB- cord-015369-72cjogxz 6947 20 80 80 CD cord-015369-72cjogxz 6947 21 - - SYM cord-015369-72cjogxz 6947 22 90 90 CD cord-015369-72cjogxz 6947 23 % % NN cord-015369-72cjogxz 6947 24 ) ) -RRB- cord-015369-72cjogxz 6947 25 gastrectomy gastrectomy NN cord-015369-72cjogxz 6947 26 . . . cord-015369-72cjogxz 6948 1 We -PRON- PRP cord-015369-72cjogxz 6948 2 analyzed analyze VBD cord-015369-72cjogxz 6948 3 serum serum NN cord-015369-72cjogxz 6948 4 values value NNS cord-015369-72cjogxz 6948 5 of of IN cord-015369-72cjogxz 6948 6 VitB12 VitB12 NNS cord-015369-72cjogxz 6948 7 in in IN cord-015369-72cjogxz 6948 8 order order NN cord-015369-72cjogxz 6948 9 to to TO cord-015369-72cjogxz 6948 10 assess assess VB cord-015369-72cjogxz 6948 11 the the DT cord-015369-72cjogxz 6948 12 need need NN cord-015369-72cjogxz 6948 13 for for IN cord-015369-72cjogxz 6948 14 parenteral parenteral JJ cord-015369-72cjogxz 6948 15 VitB12 VitB12 NNP cord-015369-72cjogxz 6948 16 supplementation supplementation NN cord-015369-72cjogxz 6948 17 in in IN cord-015369-72cjogxz 6948 18 SG SG NNP cord-015369-72cjogxz 6948 19 patients patient NNS cord-015369-72cjogxz 6948 20 . . . cord-015369-72cjogxz 6949 1 Methods method NNS cord-015369-72cjogxz 6949 2 . . . cord-015369-72cjogxz 6950 1 Between between IN cord-015369-72cjogxz 6950 2 Jan. January NNP cord-015369-72cjogxz 6950 3 2002 2002 CD cord-015369-72cjogxz 6950 4 and and CC cord-015369-72cjogxz 6950 5 Aug. August NNP cord-015369-72cjogxz 6950 6 2008 2008 CD cord-015369-72cjogxz 6950 7 , , , cord-015369-72cjogxz 6950 8 54 54 CD cord-015369-72cjogxz 6950 9 Patients patient NNS cord-015369-72cjogxz 6950 10 ( ( -LRB- cord-015369-72cjogxz 6950 11 30 30 CD cord-015369-72cjogxz 6950 12 females female NNS cord-015369-72cjogxz 6950 13 , , , cord-015369-72cjogxz 6950 14 24 24 CD cord-015369-72cjogxz 6950 15 males male NNS cord-015369-72cjogxz 6950 16 ) ) -RRB- cord-015369-72cjogxz 6950 17 underwent undergo VBD cord-015369-72cjogxz 6950 18 SG SG NNP cord-015369-72cjogxz 6950 19 at at IN cord-015369-72cjogxz 6950 20 our -PRON- PRP$ cord-015369-72cjogxz 6950 21 department department NN cord-015369-72cjogxz 6950 22 . . . cord-015369-72cjogxz 6951 1 Postoperatively postoperatively RB cord-015369-72cjogxz 6951 2 , , , cord-015369-72cjogxz 6951 3 all all DT cord-015369-72cjogxz 6951 4 patients patient NNS cord-015369-72cjogxz 6951 5 were be VBD cord-015369-72cjogxz 6951 6 advised advise VBN cord-015369-72cjogxz 6951 7 to to TO cord-015369-72cjogxz 6951 8 take take VB cord-015369-72cjogxz 6951 9 a a DT cord-015369-72cjogxz 6951 10 multivitamin multivitamin NN cord-015369-72cjogxz 6951 11 supplement supplement NN cord-015369-72cjogxz 6951 12 daily daily RB cord-015369-72cjogxz 6951 13 . . . cord-015369-72cjogxz 6952 1 Serum serum NN cord-015369-72cjogxz 6952 2 values value NNS cord-015369-72cjogxz 6952 3 of of IN cord-015369-72cjogxz 6952 4 VitB12 VitB12 NNS cord-015369-72cjogxz 6952 5 were be VBD cord-015369-72cjogxz 6952 6 obtained obtain VBN cord-015369-72cjogxz 6952 7 after after IN cord-015369-72cjogxz 6952 8 a a DT cord-015369-72cjogxz 6952 9 median median JJ cord-015369-72cjogxz 6952 10 follow follow NN cord-015369-72cjogxz 6952 11 - - HYPH cord-015369-72cjogxz 6952 12 up up NN cord-015369-72cjogxz 6952 13 of of IN cord-015369-72cjogxz 6952 14 20 20 CD cord-015369-72cjogxz 6952 15 months month NNS cord-015369-72cjogxz 6952 16 ( ( -LRB- cord-015369-72cjogxz 6952 17 range range NN cord-015369-72cjogxz 6952 18 , , , cord-015369-72cjogxz 6952 19 2.6 2.6 CD cord-015369-72cjogxz 6952 20 to to TO cord-015369-72cjogxz 6952 21 65 65 CD cord-015369-72cjogxz 6952 22 months).Results months).result NNS cord-015369-72cjogxz 6952 23 . . . cord-015369-72cjogxz 6953 1 Fifty fifty CD cord-015369-72cjogxz 6953 2 - - HYPH cord-015369-72cjogxz 6953 3 two two CD cord-015369-72cjogxz 6953 4 of of IN cord-015369-72cjogxz 6953 5 54 54 CD cord-015369-72cjogxz 6953 6 patients patient NNS cord-015369-72cjogxz 6953 7 displayed display VBD cord-015369-72cjogxz 6953 8 serum serum NN cord-015369-72cjogxz 6953 9 values value NNS cord-015369-72cjogxz 6953 10 of of IN cord-015369-72cjogxz 6953 11 VitB12 VitB12 NNS cord-015369-72cjogxz 6953 12 within within IN cord-015369-72cjogxz 6953 13 the the DT cord-015369-72cjogxz 6953 14 normal normal JJ cord-015369-72cjogxz 6953 15 range range NN cord-015369-72cjogxz 6953 16 ( ( -LRB- cord-015369-72cjogxz 6953 17 118 118 CD cord-015369-72cjogxz 6953 18 - - SYM cord-015369-72cjogxz 6953 19 716 716 CD cord-015369-72cjogxz 6953 20 pmol pmol NN cord-015369-72cjogxz 6953 21 / / SYM cord-015369-72cjogxz 6953 22 L l NN cord-015369-72cjogxz 6953 23 according accord VBG cord-015369-72cjogxz 6953 24 to to IN cord-015369-72cjogxz 6953 25 our -PRON- PRP$ cord-015369-72cjogxz 6953 26 laboratory laboratory NN cord-015369-72cjogxz 6953 27 ) ) -RRB- cord-015369-72cjogxz 6953 28 . . . cord-015369-72cjogxz 6954 1 The the DT cord-015369-72cjogxz 6954 2 median median JJ cord-015369-72cjogxz 6954 3 serum serum NN cord-015369-72cjogxz 6954 4 level level NN cord-015369-72cjogxz 6954 5 of of IN cord-015369-72cjogxz 6954 6 VitB12 VitB12 NNS cord-015369-72cjogxz 6954 7 was be VBD cord-015369-72cjogxz 6954 8 277 277 CD cord-015369-72cjogxz 6954 9 pmol pmol NN cord-015369-72cjogxz 6954 10 / / SYM cord-015369-72cjogxz 6954 11 L l NN cord-015369-72cjogxz 6954 12 ( ( -LRB- cord-015369-72cjogxz 6954 13 range range NN cord-015369-72cjogxz 6954 14 , , , cord-015369-72cjogxz 6954 15 61 61 CD cord-015369-72cjogxz 6954 16 to to TO cord-015369-72cjogxz 6954 17 876 876 CD cord-015369-72cjogxz 6954 18 pmol pmol NNP cord-015369-72cjogxz 6954 19 / / SYM cord-015369-72cjogxz 6954 20 L L NNP cord-015369-72cjogxz 6954 21 ) ) -RRB- cord-015369-72cjogxz 6954 22 . . . cord-015369-72cjogxz 6955 1 Neurological neurological JJ cord-015369-72cjogxz 6955 2 symptoms symptom NNS cord-015369-72cjogxz 6955 3 of of IN cord-015369-72cjogxz 6955 4 VitB12 VitB12 NNS cord-015369-72cjogxz 6955 5 deficiency deficiency NN cord-015369-72cjogxz 6955 6 or or CC cord-015369-72cjogxz 6955 7 macrocytosis macrocytosis NN cord-015369-72cjogxz 6955 8 were be VBD cord-015369-72cjogxz 6955 9 not not RB cord-015369-72cjogxz 6955 10 observed observe VBN cord-015369-72cjogxz 6955 11 . . . cord-015369-72cjogxz 6956 1 Conclusions conclusion NNS cord-015369-72cjogxz 6956 2 . . . cord-015369-72cjogxz 6957 1 VitB12 VitB12 NNP cord-015369-72cjogxz 6957 2 deficiency deficiency NN cord-015369-72cjogxz 6957 3 after after IN cord-015369-72cjogxz 6957 4 SG SG NNP cord-015369-72cjogxz 6957 5 is be VBZ cord-015369-72cjogxz 6957 6 rare rare JJ cord-015369-72cjogxz 6957 7 . . . cord-015369-72cjogxz 6958 1 On on IN cord-015369-72cjogxz 6958 2 the the DT cord-015369-72cjogxz 6958 3 other other JJ cord-015369-72cjogxz 6958 4 hand hand NN cord-015369-72cjogxz 6958 5 , , , cord-015369-72cjogxz 6958 6 the the DT cord-015369-72cjogxz 6958 7 median median JJ cord-015369-72cjogxz 6958 8 serum serum NN cord-015369-72cjogxz 6958 9 level level NN cord-015369-72cjogxz 6958 10 in in IN cord-015369-72cjogxz 6958 11 our -PRON- PRP$ cord-015369-72cjogxz 6958 12 SG SG NNP cord-015369-72cjogxz 6958 13 patients patient NNS cord-015369-72cjogxz 6958 14 was be VBD cord-015369-72cjogxz 6958 15 far far RB cord-015369-72cjogxz 6958 16 below below IN cord-015369-72cjogxz 6958 17 the the DT cord-015369-72cjogxz 6958 18 median median JJ cord-015369-72cjogxz 6958 19 laboratory laboratory NN cord-015369-72cjogxz 6958 20 value value NN cord-015369-72cjogxz 6958 21 ( ( -LRB- cord-015369-72cjogxz 6958 22 416 416 CD cord-015369-72cjogxz 6958 23 pmol pmol NNP cord-015369-72cjogxz 6958 24 / / SYM cord-015369-72cjogxz 6958 25 L L NNP cord-015369-72cjogxz 6958 26 ) ) -RRB- cord-015369-72cjogxz 6958 27 , , , cord-015369-72cjogxz 6958 28 and and CC cord-015369-72cjogxz 6958 29 eight eight CD cord-015369-72cjogxz 6958 30 values value NNS cord-015369-72cjogxz 6958 31 were be VBD cord-015369-72cjogxz 6958 32 within within IN cord-015369-72cjogxz 6958 33 the the DT cord-015369-72cjogxz 6958 34 so so RB cord-015369-72cjogxz 6958 35 - - HYPH cord-015369-72cjogxz 6958 36 called call VBN cord-015369-72cjogxz 6958 37 ' ' '' cord-015369-72cjogxz 6958 38 ' ' `` cord-015369-72cjogxz 6958 39 gray gray JJ cord-015369-72cjogxz 6958 40 area area NN cord-015369-72cjogxz 6958 41 ' ' '' cord-015369-72cjogxz 6958 42 ' ' '' cord-015369-72cjogxz 6959 1 ( ( -LRB- cord-015369-72cjogxz 6959 2 118 118 CD cord-015369-72cjogxz 6959 3 - - SYM cord-015369-72cjogxz 6959 4 200 200 CD cord-015369-72cjogxz 6959 5 pmol/ pmol/ NNP cord-015369-72cjogxz 6959 6 L l NN cord-015369-72cjogxz 6959 7 ) ) -RRB- cord-015369-72cjogxz 6959 8 . . . cord-015369-72cjogxz 6960 1 This this DT cord-015369-72cjogxz 6960 2 perhaps perhaps RB cord-015369-72cjogxz 6960 3 indicates indicate VBZ cord-015369-72cjogxz 6960 4 incipient incipient JJ cord-015369-72cjogxz 6960 5 VitB12 VitB12 NNP cord-015369-72cjogxz 6960 6 deficiency deficiency NN cord-015369-72cjogxz 6960 7 and and CC cord-015369-72cjogxz 6960 8 warrants warrant NNS cord-015369-72cjogxz 6960 9 further further JJ cord-015369-72cjogxz 6960 10 observation observation NN cord-015369-72cjogxz 6960 11 of of IN cord-015369-72cjogxz 6960 12 RBC RBC NNP cord-015369-72cjogxz 6960 13 indices index NNS cord-015369-72cjogxz 6960 14 and and CC cord-015369-72cjogxz 6960 15 serum serum NN cord-015369-72cjogxz 6960 16 VitB12 vitb12 NN cord-015369-72cjogxz 6960 17 values value NNS cord-015369-72cjogxz 6960 18 in in IN cord-015369-72cjogxz 6960 19 SG SG NNP cord-015369-72cjogxz 6960 20 patients patient NNS cord-015369-72cjogxz 6960 21 . . . cord-015369-72cjogxz 6961 1 Grundlagen Grundlagen NNP cord-015369-72cjogxz 6961 2 . . . cord-015369-72cjogxz 6962 1 Die die VB cord-015369-72cjogxz 6962 2 Perforation perforation NN cord-015369-72cjogxz 6962 3 der der NN cord-015369-72cjogxz 6962 4 Neoblase Neoblase NNP cord-015369-72cjogxz 6962 5 , , , cord-015369-72cjogxz 6962 6 nach nach NNP cord-015369-72cjogxz 6962 7 Zystektomie Zystektomie NNP cord-015369-72cjogxz 6962 8 , , , cord-015369-72cjogxz 6962 9 ist ist FW cord-015369-72cjogxz 6962 10 selten selten NNP cord-015369-72cjogxz 6962 11 . . . cord-015369-72cjogxz 6963 1 In in IN cord-015369-72cjogxz 6963 2 der der NN cord-015369-72cjogxz 6963 3 Literatur Literatur NNP cord-015369-72cjogxz 6963 4 sind sind NN cord-015369-72cjogxz 6963 5 solche solche NNP cord-015369-72cjogxz 6963 6 Spontanrupturen Spontanrupturen NNP cord-015369-72cjogxz 6963 7 als als NN cord-015369-72cjogxz 6963 8 einzelne einzelne NNP cord-015369-72cjogxz 6963 9 Case Case NNP cord-015369-72cjogxz 6963 10 Reports report VBZ cord-015369-72cjogxz 6963 11 beschrieben beschrieben NNP cord-015369-72cjogxz 6963 12 . . . cord-015369-72cjogxz 6964 1 Als Als NNP cord-015369-72cjogxz 6964 2 Ursache Ursache NNP cord-015369-72cjogxz 6964 3 sind sind NNP cord-015369-72cjogxz 6965 1 Ischämien Ischämien NNP cord-015369-72cjogxz 6965 2 der der NNP cord-015369-72cjogxz 6965 3 Neoblase Neoblase NNP cord-015369-72cjogxz 6965 4 oder oder NNP cord-015369-72cjogxz 6965 5 Mal Mal NNP cord-015369-72cjogxz 6965 6 - - HYPH cord-015369-72cjogxz 6965 7 Compliance Compliance NNP cord-015369-72cjogxz 6965 8 des des FW cord-015369-72cjogxz 6965 9 Patienten Patienten NNP cord-015369-72cjogxz 6965 10 bei bei NNP cord-015369-72cjogxz 6965 11 der der NN cord-015369-72cjogxz 6965 12 , , , cord-015369-72cjogxz 6965 13 , , , cord-015369-72cjogxz 6965 14 Blasenent Blasenent NNP cord-015369-72cjogxz 6965 15 - - HYPH cord-015369-72cjogxz 6965 16 leerung leerung NNP cord-015369-72cjogxz 6965 17 ' ' '' cord-015369-72cjogxz 6965 18 ' ' '' cord-015369-72cjogxz 6965 19 zu zu NNP cord-015369-72cjogxz 6965 20 nennen nennen NNP cord-015369-72cjogxz 6965 21 . . . cord-015369-72cjogxz 6966 1 In in IN cord-015369-72cjogxz 6966 2 der der NN cord-015369-72cjogxz 6966 3 vorliegenden vorliegenden VBN cord-015369-72cjogxz 6966 4 Arbeit Arbeit NNP cord-015369-72cjogxz 6966 5 wird wird NNP cord-015369-72cjogxz 6966 6 erstmalig erstmalig RB cord-015369-72cjogxz 6966 7 die die VBP cord-015369-72cjogxz 6966 8 laparoskopische laparoskopische NNP cord-015369-72cjogxz 6966 9 Neoblasen Neoblasen NNP cord-015369-72cjogxz 6966 10 - - HYPH cord-015369-72cjogxz 6966 11 Ü Ü NNP cord-015369-72cjogxz 6966 12 bernähung bernähung NNP cord-015369-72cjogxz 6966 13 beschrieben beschrieben NNP cord-015369-72cjogxz 6966 14 . . . cord-015369-72cjogxz 6967 1 Methodik Methodik NNP cord-015369-72cjogxz 6967 2 . . . cord-015369-72cjogxz 6968 1 Ein Ein NNP cord-015369-72cjogxz 6968 2 58-jähriger 58-jähriger CD cord-015369-72cjogxz 6968 3 Patient Patient NNP cord-015369-72cjogxz 6968 4 , , , cord-015369-72cjogxz 6968 5 mit mit NNP cord-015369-72cjogxz 6968 6 Status status NN cord-015369-72cjogxz 6968 7 nach nach NNP cord-015369-72cjogxz 6968 8 Zystektomie Zystektomie NNP cord-015369-72cjogxz 6968 9 mit mit NNP cord-015369-72cjogxz 6968 10 orthotoper orthotoper NN cord-015369-72cjogxz 6968 11 Anlage Anlage NNP cord-015369-72cjogxz 6968 12 einer einer NNP cord-015369-72cjogxz 6968 13 , , , cord-015369-72cjogxz 6968 14 , , , cord-015369-72cjogxz 6968 15 Ileumblase Ileumblase NNP cord-015369-72cjogxz 6968 16 ' ' POS cord-015369-72cjogxz 6968 17 ' ' '' cord-015369-72cjogxz 6968 18 wegen wegen NNP cord-015369-72cjogxz 6968 19 rezidivierendem rezidivierendem NNP cord-015369-72cjogxz 6968 20 Blasenkarzinom Blasenkarzinom NNP cord-015369-72cjogxz 6968 21 ( ( -LRB- cord-015369-72cjogxz 6968 22 T1 T1 NNP cord-015369-72cjogxz 6968 23 G3 G3 NNP cord-015369-72cjogxz 6968 24 ) ) -RRB- cord-015369-72cjogxz 6968 25 , , , cord-015369-72cjogxz 6968 26 präsentierte präsentierte NNP cord-015369-72cjogxz 6968 27 sich sich NNP cord-015369-72cjogxz 6968 28 mit mit NNP cord-015369-72cjogxz 6968 29 zunehmender zunehmender NNP cord-015369-72cjogxz 6968 30 Dysurie Dysurie NNP cord-015369-72cjogxz 6968 31 , , , cord-015369-72cjogxz 6968 32 und und RB cord-015369-72cjogxz 6968 33 fehlender fehlender NNP cord-015369-72cjogxz 6968 34 vollständiger vollständiger NNP cord-015369-72cjogxz 6968 35 Blasenentleerung Blasenentleerung NNP cord-015369-72cjogxz 6968 36 . . . cord-015369-72cjogxz 6969 1 Es Es NNP cord-015369-72cjogxz 6969 2 zeigte zeigte NNP cord-015369-72cjogxz 6969 3 sich sich NNP cord-015369-72cjogxz 6969 4 bei bei NNP cord-015369-72cjogxz 6969 5 der der NNP cord-015369-72cjogxz 6970 1 Notfallaufnahme Notfallaufnahme NNP cord-015369-72cjogxz 6970 2 ein ein NNP cord-015369-72cjogxz 6970 3 akutes akute NNS cord-015369-72cjogxz 6971 1 Abdomen Abdomen NNP cord-015369-72cjogxz 6971 2 , , , cord-015369-72cjogxz 6971 3 mit mit NNP cord-015369-72cjogxz 6971 4 generalisierter generalisierter NNP cord-015369-72cjogxz 6971 5 Peritonitis Peritonitis NNP cord-015369-72cjogxz 6971 6 . . . cord-015369-72cjogxz 6972 1 In in IN cord-015369-72cjogxz 6972 2 der der NN cord-015369-72cjogxz 6972 3 Computertomographie Computertomographie NNP cord-015369-72cjogxz 6972 4 des des NNP cord-015369-72cjogxz 6972 5 Abdomens Abdomens NNPS cord-015369-72cjogxz 6972 6 fand fand VBP cord-015369-72cjogxz 6972 7 sich sich NNP cord-015369-72cjogxz 6972 8 freie freie NNP cord-015369-72cjogxz 6972 9 Flüssigkeit Flüssigkeit NNP cord-015369-72cjogxz 6972 10 , , , cord-015369-72cjogxz 6972 11 jedoch jedoch NNP cord-015369-72cjogxz 6972 12 keine keine NNP cord-015369-72cjogxz 6972 13 freie freie NNP cord-015369-72cjogxz 6972 14 Luft Luft NNP cord-015369-72cjogxz 6972 15 und und NNP cord-015369-72cjogxz 6972 16 eine eine NNP cord-015369-72cjogxz 6972 17 prall prall NNP cord-015369-72cjogxz 6972 18 gefüllte gefüllte NNP cord-015369-72cjogxz 6972 19 Ersatzblase Ersatzblase NNP cord-015369-72cjogxz 6972 20 . . . cord-015369-72cjogxz 6973 1 Die die VB cord-015369-72cjogxz 6973 2 Katheterisierung Katheterisierung NNP cord-015369-72cjogxz 6973 3 der der VB cord-015369-72cjogxz 6973 4 Blase blase JJ cord-015369-72cjogxz 6973 5 brachte brachte NNP cord-015369-72cjogxz 6973 6 keine keine NNP cord-015369-72cjogxz 6973 7 Beschwerdeverbesserung Beschwerdeverbesserung NNP cord-015369-72cjogxz 6973 8 , , , cord-015369-72cjogxz 6973 9 auch auch NNP cord-015369-72cjogxz 6973 10 war war NN cord-015369-72cjogxz 6973 11 die die VBP cord-015369-72cjogxz 6973 12 retrograde retrograde JJ cord-015369-72cjogxz 6973 13 Füllung Füllung NNP cord-015369-72cjogxz 6973 14 mit mit NNP cord-015369-72cjogxz 6973 15 Kontrastmittel Kontrastmittel NNP cord-015369-72cjogxz 6973 16 nicht nicht NNP cord-015369-72cjogxz 6973 17 diagnostisch diagnostisch NNP cord-015369-72cjogxz 6973 18 . . . cord-015369-72cjogxz 6974 1 Laborchemisch Laborchemisch NNP cord-015369-72cjogxz 6974 2 bestand bestand NNP cord-015369-72cjogxz 6974 3 eine eine NNP cord-015369-72cjogxz 6974 4 Leukozytose Leukozytose NNP cord-015369-72cjogxz 6974 5 von von NNP cord-015369-72cjogxz 6974 6 10,300 10,300 CD cord-015369-72cjogxz 6974 7 G g NN cord-015369-72cjogxz 6974 8 / / SYM cord-015369-72cjogxz 6974 9 l l NN cord-015369-72cjogxz 6974 10 bei bei NNP cord-015369-72cjogxz 6974 11 einem einem NNP cord-015369-72cjogxz 6974 12 CRP CRP NNP cord-015369-72cjogxz 6974 13 von von NNP cord-015369-72cjogxz 6974 14 1 1 CD cord-015369-72cjogxz 6974 15 mg mg NNP cord-015369-72cjogxz 6974 16 / / SYM cord-015369-72cjogxz 6974 17 l l NN cord-015369-72cjogxz 6974 18 . . . cord-015369-72cjogxz 6974 19 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 6974 20 . . . cord-015369-72cjogxz 6975 1 In in IN cord-015369-72cjogxz 6975 2 der der NNP cord-015369-72cjogxz 6975 3 notfallmäßig notfallmäßig NNP cord-015369-72cjogxz 6975 4 angeordneten angeordneten NNP cord-015369-72cjogxz 6975 5 diagnostischen diagnostischen NNP cord-015369-72cjogxz 6975 6 Laparoskopie Laparoskopie NNP cord-015369-72cjogxz 6975 7 zeigte zeigte NN cord-015369-72cjogxz 6975 8 sich sich NNP cord-015369-72cjogxz 6976 1 i i PRP cord-015369-72cjogxz 6977 1 m m NNP cord-015369-72cjogxz 6977 2 Bereich Bereich NNP cord-015369-72cjogxz 6977 3 des des NNP cord-015369-72cjogxz 6977 4 Unterbauches Unterbauches NNP cord-015369-72cjogxz 6977 5 freie freie NNP cord-015369-72cjogxz 6977 6 Flüssigkeit Flüssigkeit NNP cord-015369-72cjogxz 6977 7 und und IN cord-015369-72cjogxz 6977 8 Fibrinauflagerungen Fibrinauflagerungen NNP cord-015369-72cjogxz 6977 9 i -PRON- PRP cord-015369-72cjogxz 6977 10 m be VBP cord-015369-72cjogxz 6977 11 Bereich Bereich NNP cord-015369-72cjogxz 6977 12 der der NNP cord-015369-72cjogxz 6977 13 Ersatzblase Ersatzblase NNP cord-015369-72cjogxz 6977 14 . . . cord-015369-72cjogxz 6978 1 Nach Nach NNP cord-015369-72cjogxz 6978 2 Füllen Füllen NNP cord-015369-72cjogxz 6978 3 der der NNP cord-015369-72cjogxz 6978 4 Neoblase Neoblase NNP cord-015369-72cjogxz 6978 5 mit mit NN cord-015369-72cjogxz 6978 6 ca ca NNP cord-015369-72cjogxz 6978 7 . . . cord-015369-72cjogxz 6979 1 500 500 CD cord-015369-72cjogxz 6979 2 ml ml NNPS cord-015369-72cjogxz 6979 3 Methylenblau Methylenblau NNP cord-015369-72cjogxz 6979 4 konnte konnte NNP cord-015369-72cjogxz 6979 5 eine eine NNP cord-015369-72cjogxz 6979 6 0,5 0,5 NN cord-015369-72cjogxz 6979 7 Â â NN cord-015369-72cjogxz 6979 8 0,5 0,5 CD cord-015369-72cjogxz 6979 9 cm cm NN cord-015369-72cjogxz 6980 1 messende messende NNP cord-015369-72cjogxz 6980 2 Perforationsstelle Perforationsstelle NNP cord-015369-72cjogxz 6980 3 , , , cord-015369-72cjogxz 6980 4 welche welche NNP cord-015369-72cjogxz 6980 5 laparoskopisch laparoskopisch NNP cord-015369-72cjogxz 6980 6 übernäht übernäht . cord-015369-72cjogxz 6980 7 werden werden NNP cord-015369-72cjogxz 6980 8 konnte konnte NNP cord-015369-72cjogxz 6980 9 . . . cord-015369-72cjogxz 6981 1 Der Der NNP cord-015369-72cjogxz 6981 2 postoperative postoperative JJ cord-015369-72cjogxz 6981 3 Verlauf Verlauf NNP cord-015369-72cjogxz 6981 4 war war NN cord-015369-72cjogxz 6981 5 unauffällig unauffällig NN cord-015369-72cjogxz 6981 6 , , , cord-015369-72cjogxz 6981 7 Entlassung Entlassung NNP cord-015369-72cjogxz 6981 8 des des NNP cord-015369-72cjogxz 6981 9 Patienten Patienten NNP cord-015369-72cjogxz 6981 10 mit mit NNP cord-015369-72cjogxz 6981 11 klarer klarer NNP cord-015369-72cjogxz 6981 12 Instruktion Instruktion NNP cord-015369-72cjogxz 6981 13 zur zur NNP cord-015369-72cjogxz 6981 14 regelmässigen regelmässigen NNP cord-015369-72cjogxz 6981 15 Blasenentleerung Blasenentleerung NNP cord-015369-72cjogxz 6981 16 nach nach NNP cord-015369-72cjogxz 6981 17 10 10 CD cord-015369-72cjogxz 6981 18 Tagen Tagen NNP cord-015369-72cjogxz 6981 19 . . . cord-015369-72cjogxz 6982 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 6982 2 . . . cord-015369-72cjogxz 6983 1 Das Das NNP cord-015369-72cjogxz 6983 2 Auftreten Auftreten NNP cord-015369-72cjogxz 6984 1 einer einer NNP cord-015369-72cjogxz 6985 1 Spontanruptur Spontanruptur NNP cord-015369-72cjogxz 6985 2 der der NN cord-015369-72cjogxz 6985 3 Neoblase Neoblase NNP cord-015369-72cjogxz 6985 4 ist ist NN cord-015369-72cjogxz 6986 1 selten selten NNP cord-015369-72cjogxz 6986 2 . . . cord-015369-72cjogxz 6987 1 Daran Daran NNP cord-015369-72cjogxz 6987 2 denken denken NNP cord-015369-72cjogxz 6988 1 und und NNP cord-015369-72cjogxz 6988 2 die die VB cord-015369-72cjogxz 6989 1 Diagnose diagnose VB cord-015369-72cjogxz 6989 2 erzwingen erzwingen NNP cord-015369-72cjogxz 6989 3 Background background NN cord-015369-72cjogxz 6989 4 . . . cord-015369-72cjogxz 6990 1 Posters poster NNS cord-015369-72cjogxz 6990 2 are be VBP cord-015369-72cjogxz 6990 3 used use VBN cord-015369-72cjogxz 6990 4 widely widely RB cord-015369-72cjogxz 6990 5 at at IN cord-015369-72cjogxz 6990 6 surgical surgical JJ cord-015369-72cjogxz 6990 7 meetings meeting NNS cord-015369-72cjogxz 6990 8 to to TO cord-015369-72cjogxz 6990 9 present present VB cord-015369-72cjogxz 6990 10 news news NN cord-015369-72cjogxz 6990 11 of of IN cord-015369-72cjogxz 6990 12 clinical clinical JJ cord-015369-72cjogxz 6990 13 and and CC cord-015369-72cjogxz 6990 14 scientific scientific JJ cord-015369-72cjogxz 6990 15 research research NN cord-015369-72cjogxz 6990 16 . . . cord-015369-72cjogxz 6991 1 Posters poster NNS cord-015369-72cjogxz 6991 2 are be VBP cord-015369-72cjogxz 6991 3 presented present VBN cord-015369-72cjogxz 6991 4 in in IN cord-015369-72cjogxz 6991 5 special special JJ cord-015369-72cjogxz 6991 6 areas area NNS cord-015369-72cjogxz 6991 7 preferably preferably RB cord-015369-72cjogxz 6991 8 at at IN cord-015369-72cjogxz 6991 9 meeting meeting NN cord-015369-72cjogxz 6991 10 points point NNS cord-015369-72cjogxz 6991 11 and and CC cord-015369-72cjogxz 6991 12 provide provide VB cord-015369-72cjogxz 6991 13 a a DT cord-015369-72cjogxz 6991 14 relaxed relaxed JJ cord-015369-72cjogxz 6991 15 environment environment NN cord-015369-72cjogxz 6991 16 for for IN cord-015369-72cjogxz 6991 17 exchanging exchange VBG cord-015369-72cjogxz 6991 18 ideas idea NNS cord-015369-72cjogxz 6991 19 . . . cord-015369-72cjogxz 6992 1 Especially especially RB cord-015369-72cjogxz 6992 2 for for IN cord-015369-72cjogxz 6992 3 young young JJ cord-015369-72cjogxz 6992 4 scientists scientist NNS cord-015369-72cjogxz 6992 5 and and CC cord-015369-72cjogxz 6992 6 surgeons surgeon NNS cord-015369-72cjogxz 6993 1 poster poster NN cord-015369-72cjogxz 6993 2 presentations presentation NNS cord-015369-72cjogxz 6993 3 often often RB cord-015369-72cjogxz 6993 4 are be VBP cord-015369-72cjogxz 6993 5 the the DT cord-015369-72cjogxz 6993 6 first first JJ cord-015369-72cjogxz 6993 7 scientific scientific JJ cord-015369-72cjogxz 6993 8 contacts contact NNS cord-015369-72cjogxz 6993 9 to to IN cord-015369-72cjogxz 6993 10 the the DT cord-015369-72cjogxz 6993 11 surgical surgical JJ cord-015369-72cjogxz 6993 12 community community NN cord-015369-72cjogxz 6993 13 . . . cord-015369-72cjogxz 6994 1 Many many JJ cord-015369-72cjogxz 6994 2 societies society NNS cord-015369-72cjogxz 6994 3 award award VBP cord-015369-72cjogxz 6994 4 '' '' '' cord-015369-72cjogxz 6995 1 best good JJS cord-015369-72cjogxz 6995 2 poster poster NN cord-015369-72cjogxz 6995 3 prices price NNS cord-015369-72cjogxz 6995 4 ' ' '' cord-015369-72cjogxz 6995 5 ' ' '' cord-015369-72cjogxz 6995 6 however however RB cord-015369-72cjogxz 6995 7 mostly mostly RB cord-015369-72cjogxz 6995 8 without without IN cord-015369-72cjogxz 6995 9 uniformly uniformly RB cord-015369-72cjogxz 6995 10 agreed agree VBN cord-015369-72cjogxz 6995 11 assessment assessment NN cord-015369-72cjogxz 6995 12 methods method NNS cord-015369-72cjogxz 6995 13 . . . cord-015369-72cjogxz 6996 1 We -PRON- PRP cord-015369-72cjogxz 6996 2 generated generate VBD cord-015369-72cjogxz 6996 3 poster poster NN cord-015369-72cjogxz 6996 4 assessment assessment NN cord-015369-72cjogxz 6996 5 guidelines guideline NNS cord-015369-72cjogxz 6996 6 in in IN cord-015369-72cjogxz 6996 7 a a DT cord-015369-72cjogxz 6996 8 checklist checklist NN cord-015369-72cjogxz 6996 9 to to TO cord-015369-72cjogxz 6996 10 evaluate evaluate VB cord-015369-72cjogxz 6996 11 posters poster NNS cord-015369-72cjogxz 6996 12 at at IN cord-015369-72cjogxz 6996 13 surgical surgical JJ cord-015369-72cjogxz 6996 14 meetings meeting NNS cord-015369-72cjogxz 6996 15 . . . cord-015369-72cjogxz 6997 1 Methods method NNS cord-015369-72cjogxz 6997 2 . . . cord-015369-72cjogxz 6998 1 According accord VBG cord-015369-72cjogxz 6998 2 to to IN cord-015369-72cjogxz 6998 3 well well RB cord-015369-72cjogxz 6998 4 published publish VBN cord-015369-72cjogxz 6998 5 guidelines guideline NNS cord-015369-72cjogxz 6998 6 for for IN cord-015369-72cjogxz 6998 7 the the DT cord-015369-72cjogxz 6998 8 designing designing NN cord-015369-72cjogxz 6998 9 and and CC cord-015369-72cjogxz 6998 10 presentation presentation NN cord-015369-72cjogxz 6998 11 of of IN cord-015369-72cjogxz 6998 12 posters poster NNS cord-015369-72cjogxz 6998 13 we -PRON- PRP cord-015369-72cjogxz 6998 14 constructed construct VBD cord-015369-72cjogxz 6998 15 an an DT cord-015369-72cjogxz 6998 16 evaluation evaluation NN cord-015369-72cjogxz 6998 17 checklist checklist NN cord-015369-72cjogxz 6998 18 consisting consist VBG cord-015369-72cjogxz 6998 19 of of IN cord-015369-72cjogxz 6998 20 three three CD cord-015369-72cjogxz 6998 21 main main JJ cord-015369-72cjogxz 6998 22 parts part NNS cord-015369-72cjogxz 6998 23 : : : cord-015369-72cjogxz 6998 24 presentation presentation NN cord-015369-72cjogxz 6998 25 , , , cord-015369-72cjogxz 6998 26 design design NN cord-015369-72cjogxz 6998 27 of of IN cord-015369-72cjogxz 6998 28 the the DT cord-015369-72cjogxz 6998 29 poster poster NN cord-015369-72cjogxz 6998 30 , , , cord-015369-72cjogxz 6998 31 background background NN cord-015369-72cjogxz 6998 32 and and CC cord-015369-72cjogxz 6998 33 purpose purpose NN cord-015369-72cjogxz 6998 34 of of IN cord-015369-72cjogxz 6998 35 the the DT cord-015369-72cjogxz 6998 36 poster poster NN cord-015369-72cjogxz 6998 37 ( ( -LRB- cord-015369-72cjogxz 6998 38 scientific scientific JJ cord-015369-72cjogxz 6998 39 impact).Results impact).result NNS cord-015369-72cjogxz 6998 40 . . . cord-015369-72cjogxz 6999 1 The the DT cord-015369-72cjogxz 6999 2 table table NN cord-015369-72cjogxz 6999 3 shows show VBZ cord-015369-72cjogxz 6999 4 our -PRON- PRP$ cord-015369-72cjogxz 6999 5 recommendation recommendation NN cord-015369-72cjogxz 6999 6 for for IN cord-015369-72cjogxz 6999 7 the the DT cord-015369-72cjogxz 6999 8 checklist checklist NN cord-015369-72cjogxz 6999 9 in in IN cord-015369-72cjogxz 6999 10 three three CD cord-015369-72cjogxz 6999 11 parts part NNS cord-015369-72cjogxz 6999 12 . . . cord-015369-72cjogxz 7000 1 Conclusions conclusion NNS cord-015369-72cjogxz 7000 2 . . . cord-015369-72cjogxz 7001 1 Awarding award VBG cord-015369-72cjogxz 7001 2 poster poster NN cord-015369-72cjogxz 7001 3 prices price NNS cord-015369-72cjogxz 7001 4 are be VBP cord-015369-72cjogxz 7001 5 stimuli stimulus NNS cord-015369-72cjogxz 7001 6 especially especially RB cord-015369-72cjogxz 7001 7 for for IN cord-015369-72cjogxz 7001 8 young young JJ cord-015369-72cjogxz 7001 9 scientists scientist NNS cord-015369-72cjogxz 7001 10 to to TO cord-015369-72cjogxz 7001 11 participate participate VB cord-015369-72cjogxz 7001 12 at at IN cord-015369-72cjogxz 7001 13 surgical surgical JJ cord-015369-72cjogxz 7001 14 conferences conference NNS cord-015369-72cjogxz 7001 15 and and CC cord-015369-72cjogxz 7001 16 meetings meeting NNS cord-015369-72cjogxz 7001 17 . . . cord-015369-72cjogxz 7002 1 However however RB cord-015369-72cjogxz 7002 2 it -PRON- PRP cord-015369-72cjogxz 7002 3 can can MD cord-015369-72cjogxz 7002 4 be be VB cord-015369-72cjogxz 7002 5 very very RB cord-015369-72cjogxz 7002 6 disappointing disappointing JJ cord-015369-72cjogxz 7002 7 if if IN cord-015369-72cjogxz 7002 8 great great JJ cord-015369-72cjogxz 7002 9 efforts effort NNS cord-015369-72cjogxz 7002 10 have have VBP cord-015369-72cjogxz 7002 11 been be VBN cord-015369-72cjogxz 7002 12 applied apply VBN cord-015369-72cjogxz 7002 13 to to TO cord-015369-72cjogxz 7002 14 prepare prepare VB cord-015369-72cjogxz 7002 15 posters poster NNS cord-015369-72cjogxz 7002 16 and and CC cord-015369-72cjogxz 7002 17 presentations presentation NNS cord-015369-72cjogxz 7002 18 and and CC cord-015369-72cjogxz 7002 19 it -PRON- PRP cord-015369-72cjogxz 7002 20 is be VBZ cord-015369-72cjogxz 7002 21 not not RB cord-015369-72cjogxz 7002 22 possible possible JJ cord-015369-72cjogxz 7002 23 to to TO cord-015369-72cjogxz 7002 24 see see VB cord-015369-72cjogxz 7002 25 through through IN cord-015369-72cjogxz 7002 26 the the DT cord-015369-72cjogxz 7002 27 evaluation evaluation NN cord-015369-72cjogxz 7002 28 process process NN cord-015369-72cjogxz 7002 29 . . . cord-015369-72cjogxz 7003 1 Therefore therefore RB cord-015369-72cjogxz 7003 2 the the DT cord-015369-72cjogxz 7003 3 evaluation evaluation NN cord-015369-72cjogxz 7003 4 process process NN cord-015369-72cjogxz 7003 5 has have VBZ cord-015369-72cjogxz 7003 6 to to TO cord-015369-72cjogxz 7003 7 be be VB cord-015369-72cjogxz 7003 8 objective objective JJ cord-015369-72cjogxz 7003 9 as as RB cord-015369-72cjogxz 7003 10 well well RB cord-015369-72cjogxz 7003 11 as as IN cord-015369-72cjogxz 7003 12 open open JJ cord-015369-72cjogxz 7003 13 and and CC cord-015369-72cjogxz 7003 14 above above IN cord-015369-72cjogxz 7003 15 board board NN cord-015369-72cjogxz 7003 16 . . . cord-015369-72cjogxz 7004 1 The the DT cord-015369-72cjogxz 7004 2 posters poster NNS cord-015369-72cjogxz 7004 3 should should MD cord-015369-72cjogxz 7004 4 be be VB cord-015369-72cjogxz 7004 5 evaluated evaluate VBN cord-015369-72cjogxz 7004 6 by by IN cord-015369-72cjogxz 7004 7 independent independent JJ cord-015369-72cjogxz 7004 8 scientist scientist NN cord-015369-72cjogxz 7004 9 of of IN cord-015369-72cjogxz 7004 10 different different JJ cord-015369-72cjogxz 7004 11 institutions institution NNS cord-015369-72cjogxz 7004 12 . . . cord-015369-72cjogxz 7005 1 Our -PRON- PRP$ cord-015369-72cjogxz 7005 2 assessment assessment NN cord-015369-72cjogxz 7005 3 guidelines guideline NNS cord-015369-72cjogxz 7005 4 and and CC cord-015369-72cjogxz 7005 5 checklist checklist NN cord-015369-72cjogxz 7005 6 meet meet VBP cord-015369-72cjogxz 7005 7 these these DT cord-015369-72cjogxz 7005 8 mentioned mention VBN cord-015369-72cjogxz 7005 9 requirements requirement NNS cord-015369-72cjogxz 7005 10 . . . cord-015369-72cjogxz 7006 1 An an DT cord-015369-72cjogxz 7006 2 examination examination NN cord-015369-72cjogxz 7006 3 of of IN cord-015369-72cjogxz 7006 4 the the DT cord-015369-72cjogxz 7006 5 quality quality NN cord-015369-72cjogxz 7006 6 will will MD cord-015369-72cjogxz 7006 7 show show VB cord-015369-72cjogxz 7006 8 if if IN cord-015369-72cjogxz 7006 9 this this DT cord-015369-72cjogxz 7006 10 tool tool NN cord-015369-72cjogxz 7006 11 is be VBZ cord-015369-72cjogxz 7006 12 applicable applicable JJ cord-015369-72cjogxz 7006 13 or or CC cord-015369-72cjogxz 7006 14 not not RB cord-015369-72cjogxz 7006 15 . . . cord-015369-72cjogxz 7007 1 Background background NN cord-015369-72cjogxz 7007 2 . . . cord-015369-72cjogxz 7008 1 Complications complication NNS cord-015369-72cjogxz 7008 2 after after IN cord-015369-72cjogxz 7008 3 extensive extensive JJ cord-015369-72cjogxz 7008 4 thoracic thoracic JJ cord-015369-72cjogxz 7008 5 surgery surgery NN cord-015369-72cjogxz 7008 6 can can MD cord-015369-72cjogxz 7008 7 be be VB cord-015369-72cjogxz 7008 8 complex complex JJ cord-015369-72cjogxz 7008 9 and and CC cord-015369-72cjogxz 7008 10 life life NN cord-015369-72cjogxz 7008 11 threatening threaten VBG cord-015369-72cjogxz 7008 12 , , , cord-015369-72cjogxz 7008 13 and and CC cord-015369-72cjogxz 7008 14 diagnostic diagnostic JJ cord-015369-72cjogxz 7008 15 pathways pathway NNS cord-015369-72cjogxz 7008 16 are be VBP cord-015369-72cjogxz 7008 17 potentially potentially RB cord-015369-72cjogxz 7008 18 difficult difficult JJ cord-015369-72cjogxz 7008 19 . . . cord-015369-72cjogxz 7009 1 We -PRON- PRP cord-015369-72cjogxz 7009 2 present present VBP cord-015369-72cjogxz 7009 3 the the DT cord-015369-72cjogxz 7009 4 case case NN cord-015369-72cjogxz 7009 5 of of IN cord-015369-72cjogxz 7009 6 a a DT cord-015369-72cjogxz 7009 7 66 66 CD cord-015369-72cjogxz 7009 8 years year NNS cord-015369-72cjogxz 7009 9 old old JJ cord-015369-72cjogxz 7009 10 patient patient NN cord-015369-72cjogxz 7009 11 who who WP cord-015369-72cjogxz 7009 12 postoperatively postoperatively RB cord-015369-72cjogxz 7009 13 developed develop VBD cord-015369-72cjogxz 7009 14 an an DT cord-015369-72cjogxz 7009 15 acute acute JJ cord-015369-72cjogxz 7009 16 displacement displacement NN cord-015369-72cjogxz 7009 17 of of IN cord-015369-72cjogxz 7009 18 mediastinal mediastinal JJ cord-015369-72cjogxz 7009 19 structures structure NNS cord-015369-72cjogxz 7009 20 by by IN cord-015369-72cjogxz 7009 21 abdominal abdominal JJ cord-015369-72cjogxz 7009 22 viscera viscera NN cord-015369-72cjogxz 7009 23 after after IN cord-015369-72cjogxz 7009 24 extrapleural extrapleural JJ cord-015369-72cjogxz 7009 25 pneumonectomy pneumonectomy NN cord-015369-72cjogxz 7009 26 . . . cord-015369-72cjogxz 7010 1 Methods method NNS cord-015369-72cjogxz 7010 2 . . . cord-015369-72cjogxz 7011 1 The the DT cord-015369-72cjogxz 7011 2 patient patient NN cord-015369-72cjogxz 7011 3 was be VBD cord-015369-72cjogxz 7011 4 treated treat VBN cord-015369-72cjogxz 7011 5 with with IN cord-015369-72cjogxz 7011 6 extrapleural extrapleural JJ cord-015369-72cjogxz 7011 7 pneumonectomy pneumonectomy NN cord-015369-72cjogxz 7011 8 in in IN cord-015369-72cjogxz 7011 9 a a DT cord-015369-72cjogxz 7011 10 curative curative JJ cord-015369-72cjogxz 7011 11 intention intention NN cord-015369-72cjogxz 7011 12 . . . cord-015369-72cjogxz 7012 1 Diaphragm diaphragm NN cord-015369-72cjogxz 7012 2 was be VBD cord-015369-72cjogxz 7012 3 reconstructed reconstruct VBN cord-015369-72cjogxz 7012 4 with with IN cord-015369-72cjogxz 7012 5 an an DT cord-015369-72cjogxz 7012 6 artificial artificial JJ cord-015369-72cjogxz 7012 7 mesh mesh NN cord-015369-72cjogxz 7012 8 implant implant NN cord-015369-72cjogxz 7012 9 after after IN cord-015369-72cjogxz 7012 10 a a DT cord-015369-72cjogxz 7012 11 major major JJ cord-015369-72cjogxz 7012 12 part part NN cord-015369-72cjogxz 7012 13 of of IN cord-015369-72cjogxz 7012 14 the the DT cord-015369-72cjogxz 7012 15 diaphragm diaphragm NN cord-015369-72cjogxz 7012 16 had have VBD cord-015369-72cjogxz 7012 17 to to TO cord-015369-72cjogxz 7012 18 be be VB cord-015369-72cjogxz 7012 19 resected resect VBN cord-015369-72cjogxz 7012 20 . . . cord-015369-72cjogxz 7013 1 The the DT cord-015369-72cjogxz 7013 2 mesh mesh NN cord-015369-72cjogxz 7013 3 was be VBD cord-015369-72cjogxz 7013 4 fixed fix VBN cord-015369-72cjogxz 7013 5 with with IN cord-015369-72cjogxz 7013 6 interrupted interrupted JJ cord-015369-72cjogxz 7013 7 non non JJ cord-015369-72cjogxz 7013 8 - - JJ cord-015369-72cjogxz 7013 9 absorbable absorbable JJ cord-015369-72cjogxz 7013 10 sutures suture NNS cord-015369-72cjogxz 7013 11 . . . cord-015369-72cjogxz 7014 1 Results result NNS cord-015369-72cjogxz 7014 2 . . . cord-015369-72cjogxz 7015 1 Due due IN cord-015369-72cjogxz 7015 2 to to IN cord-015369-72cjogxz 7015 3 failure failure NN cord-015369-72cjogxz 7015 4 of of IN cord-015369-72cjogxz 7015 5 the the DT cord-015369-72cjogxz 7015 6 diaphragmatic diaphragmatic JJ cord-015369-72cjogxz 7015 7 reconstruction reconstruction NN cord-015369-72cjogxz 7015 8 and and CC cord-015369-72cjogxz 7015 9 subsequent subsequent JJ cord-015369-72cjogxz 7015 10 displacement displacement NN cord-015369-72cjogxz 7015 11 of of IN cord-015369-72cjogxz 7015 12 abdominal abdominal JJ cord-015369-72cjogxz 7015 13 strucutes strucute NNS cord-015369-72cjogxz 7015 14 , , , cord-015369-72cjogxz 7015 15 acute acute JJ cord-015369-72cjogxz 7015 16 displacement displacement NN cord-015369-72cjogxz 7015 17 of of IN cord-015369-72cjogxz 7015 18 the the DT cord-015369-72cjogxz 7015 19 mediastinal mediastinal JJ cord-015369-72cjogxz 7015 20 structures structure NNS cord-015369-72cjogxz 7015 21 occurred occur VBD cord-015369-72cjogxz 7015 22 . . . cord-015369-72cjogxz 7016 1 Initial initial JJ cord-015369-72cjogxz 7016 2 X x NN cord-015369-72cjogxz 7016 3 - - NN cord-015369-72cjogxz 7016 4 ray ray NN cord-015369-72cjogxz 7016 5 led lead VBD cord-015369-72cjogxz 7016 6 to to IN cord-015369-72cjogxz 7016 7 the the DT cord-015369-72cjogxz 7016 8 false false JJ cord-015369-72cjogxz 7016 9 diagnosis diagnosis NN cord-015369-72cjogxz 7016 10 of of IN cord-015369-72cjogxz 7016 11 suspected suspect VBN cord-015369-72cjogxz 7016 12 tension tension NN cord-015369-72cjogxz 7016 13 pneumothorax pneumothorax NN cord-015369-72cjogxz 7016 14 with with IN cord-015369-72cjogxz 7016 15 a a DT cord-015369-72cjogxz 7016 16 classical classical JJ cord-015369-72cjogxz 7016 17 picture picture NN cord-015369-72cjogxz 7016 18 of of IN cord-015369-72cjogxz 7016 19 mediastinal mediastinal JJ cord-015369-72cjogxz 7016 20 shift shift NN cord-015369-72cjogxz 7016 21 . . . cord-015369-72cjogxz 7017 1 The the DT cord-015369-72cjogxz 7017 2 correct correct JJ cord-015369-72cjogxz 7017 3 diagnosis diagnosis NN cord-015369-72cjogxz 7017 4 was be VBD cord-015369-72cjogxz 7017 5 diagnosed diagnose VBN cord-015369-72cjogxz 7017 6 by by IN cord-015369-72cjogxz 7017 7 CT CT NNP cord-015369-72cjogxz 7017 8 scan scan NNP cord-015369-72cjogxz 7017 9 only only RB cord-015369-72cjogxz 7017 10 . . . cord-015369-72cjogxz 7018 1 The the DT cord-015369-72cjogxz 7018 2 treatment treatment NN cord-015369-72cjogxz 7018 3 of of IN cord-015369-72cjogxz 7018 4 choice choice NN cord-015369-72cjogxz 7018 5 therefore therefore RB cord-015369-72cjogxz 7018 6 was be VBD cord-015369-72cjogxz 7018 7 operative operative JJ cord-015369-72cjogxz 7018 8 revision revision NN cord-015369-72cjogxz 7018 9 and and CC cord-015369-72cjogxz 7018 10 not not RB cord-015369-72cjogxz 7018 11 the the DT cord-015369-72cjogxz 7018 12 placement placement NN cord-015369-72cjogxz 7018 13 of of IN cord-015369-72cjogxz 7018 14 a a DT cord-015369-72cjogxz 7018 15 chest chest NN cord-015369-72cjogxz 7018 16 tube tube NN cord-015369-72cjogxz 7018 17 for for IN cord-015369-72cjogxz 7018 18 decompression decompression NN cord-015369-72cjogxz 7018 19 . . . cord-015369-72cjogxz 7019 1 Conclusions conclusion NNS cord-015369-72cjogxz 7019 2 . . . cord-015369-72cjogxz 7020 1 This this DT cord-015369-72cjogxz 7020 2 rare rare JJ cord-015369-72cjogxz 7020 3 but but CC cord-015369-72cjogxz 7020 4 very very RB cord-015369-72cjogxz 7020 5 dangeours dangeours JJ cord-015369-72cjogxz 7020 6 complication complication NN cord-015369-72cjogxz 7020 7 after after IN cord-015369-72cjogxz 7020 8 extensive extensive JJ cord-015369-72cjogxz 7020 9 cytoreductive cytoreductive JJ cord-015369-72cjogxz 7020 10 surgery surgery NN cord-015369-72cjogxz 7020 11 for for IN cord-015369-72cjogxz 7020 12 malignant malignant JJ cord-015369-72cjogxz 7020 13 pleural pleural JJ cord-015369-72cjogxz 7020 14 mesothelioma mesothelioma NN cord-015369-72cjogxz 7020 15 is be VBZ cord-015369-72cjogxz 7020 16 important important JJ cord-015369-72cjogxz 7020 17 to to TO cord-015369-72cjogxz 7020 18 know know VB cord-015369-72cjogxz 7020 19 for for IN cord-015369-72cjogxz 7020 20 every every DT cord-015369-72cjogxz 7020 21 general general JJ cord-015369-72cjogxz 7020 22 surgeon surgeon NN cord-015369-72cjogxz 7020 23 . . . cord-015369-72cjogxz 7021 1 Interestingly interestingly RB cord-015369-72cjogxz 7021 2 the the DT cord-015369-72cjogxz 7021 3 displaced displace VBN cord-015369-72cjogxz 7021 4 stomach stomach NN cord-015369-72cjogxz 7021 5 was be VBD cord-015369-72cjogxz 7021 6 massively massively RB cord-015369-72cjogxz 7021 7 bloated bloated JJ cord-015369-72cjogxz 7021 8 due due IN cord-015369-72cjogxz 7021 9 to to IN cord-015369-72cjogxz 7021 10 ' ' '' cord-015369-72cjogxz 7021 11 ' ' '' cord-015369-72cjogxz 7021 12 air air NN cord-015369-72cjogxz 7021 13 trapment trapment NNP cord-015369-72cjogxz 7021 14 ' ' '' cord-015369-72cjogxz 7021 15 ' ' '' cord-015369-72cjogxz 7021 16 , , , cord-015369-72cjogxz 7021 17 which which WDT cord-015369-72cjogxz 7021 18 led lead VBD cord-015369-72cjogxz 7021 19 to to IN cord-015369-72cjogxz 7021 20 the the DT cord-015369-72cjogxz 7021 21 false false JJ cord-015369-72cjogxz 7021 22 diagnosis diagnosis NN cord-015369-72cjogxz 7021 23 . . . cord-015369-72cjogxz 7022 1 Only only RB cord-015369-72cjogxz 7022 2 retrospectively retrospectively RB cord-015369-72cjogxz 7022 3 , , , cord-015369-72cjogxz 7022 4 a a DT cord-015369-72cjogxz 7022 5 very very RB cord-015369-72cjogxz 7022 6 thin thin JJ cord-015369-72cjogxz 7022 7 line line NN cord-015369-72cjogxz 7022 8 in in IN cord-015369-72cjogxz 7022 9 conventional conventional JJ cord-015369-72cjogxz 7022 10 X x NN cord-015369-72cjogxz 7022 11 - - NN cord-015369-72cjogxz 7022 12 ray ray NN cord-015369-72cjogxz 7022 13 was be VBD cord-015369-72cjogxz 7022 14 found find VBN cord-015369-72cjogxz 7022 15 being be VBG cord-015369-72cjogxz 7022 16 the the DT cord-015369-72cjogxz 7022 17 stomach stomach NN cord-015369-72cjogxz 7022 18 wall wall NN cord-015369-72cjogxz 7022 19 . . . cord-015369-72cjogxz 7023 1 In in IN cord-015369-72cjogxz 7023 2 situations situation NNS cord-015369-72cjogxz 7023 3 of of IN cord-015369-72cjogxz 7023 4 postoperative postoperative JJ cord-015369-72cjogxz 7023 5 impairment impairment NN cord-015369-72cjogxz 7023 6 of of IN cord-015369-72cjogxz 7023 7 a a DT cord-015369-72cjogxz 7023 8 patient patient NN cord-015369-72cjogxz 7023 9 's 's POS cord-015369-72cjogxz 7023 10 condition condition NN cord-015369-72cjogxz 7023 11 after after IN cord-015369-72cjogxz 7023 12 extensive extensive JJ cord-015369-72cjogxz 7023 13 thoracic thoracic JJ cord-015369-72cjogxz 7023 14 surgery surgery NN cord-015369-72cjogxz 7023 15 , , , cord-015369-72cjogxz 7023 16 we -PRON- PRP cord-015369-72cjogxz 7023 17 recommend recommend VBP cord-015369-72cjogxz 7023 18 to to TO cord-015369-72cjogxz 7023 19 perform perform VB cord-015369-72cjogxz 7023 20 further further JJ cord-015369-72cjogxz 7023 21 diagnostic diagnostic JJ cord-015369-72cjogxz 7023 22 measures measure NNS cord-015369-72cjogxz 7023 23 with with IN cord-015369-72cjogxz 7023 24 early early JJ cord-015369-72cjogxz 7023 25 CT CT NNP cord-015369-72cjogxz 7023 26 scan scan NN cord-015369-72cjogxz 7023 27 . . . cord-015369-72cjogxz 7024 1 In in IN cord-015369-72cjogxz 7024 2 this this DT cord-015369-72cjogxz 7024 3 situation situation NN cord-015369-72cjogxz 7024 4 placement placement NN cord-015369-72cjogxz 7024 5 of of IN cord-015369-72cjogxz 7024 6 a a DT cord-015369-72cjogxz 7024 7 chest chest NN cord-015369-72cjogxz 7024 8 tube tube NN cord-015369-72cjogxz 7024 9 would would MD cord-015369-72cjogxz 7024 10 have have VB cord-015369-72cjogxz 7024 11 been be VBN cord-015369-72cjogxz 7024 12 potentially potentially RB cord-015369-72cjogxz 7024 13 harmful harmful JJ cord-015369-72cjogxz 7024 14 to to IN cord-015369-72cjogxz 7024 15 the the DT cord-015369-72cjogxz 7024 16 patient patient NN cord-015369-72cjogxz 7024 17 who who WP cord-015369-72cjogxz 7024 18 recovered recover VBD cord-015369-72cjogxz 7024 19 without without IN cord-015369-72cjogxz 7024 20 further further JJ cord-015369-72cjogxz 7024 21 complication complication NN cord-015369-72cjogxz 7024 22 . . . cord-015369-72cjogxz 7025 1 Erfolgreiche Erfolgreiche NNP cord-015369-72cjogxz 7025 2 konservative konservative NNP cord-015369-72cjogxz 7025 3 Therapie Therapie NNP cord-015369-72cjogxz 7025 4 des des FW cord-015369-72cjogxz 7025 5 postoperativen postoperativen VBN cord-015369-72cjogxz 7025 6 Chylothoraxein Chylothoraxein NNP cord-015369-72cjogxz 7025 7 klinischer klinischer NN cord-015369-72cjogxz 7025 8 Algorithmus Algorithmus NNP cord-015369-72cjogxz 7025 9 Grundlagen Grundlagen NNP cord-015369-72cjogxz 7025 10 . . . cord-015369-72cjogxz 7026 1 Der Der NNP cord-015369-72cjogxz 7026 2 Chylothorax Chylothorax NNP cord-015369-72cjogxz 7026 3 nach nach NNP cord-015369-72cjogxz 7026 4 thorakalen thorakalen NNP cord-015369-72cjogxz 7027 1 chirurgischen chirurgischen NNP cord-015369-72cjogxz 7027 2 Eingriffen Eingriffen NNP cord-015369-72cjogxz 7027 3 ist ist NNP cord-015369-72cjogxz 7027 4 eine eine NN cord-015369-72cjogxz 7028 1 seltene seltene NNP cord-015369-72cjogxz 7028 2 aber aber NNP cord-015369-72cjogxz 7028 3 wegen wegen NNP cord-015369-72cjogxz 7028 4 seiner seiner NNP cord-015369-72cjogxz 7028 5 metabolischen metabolischen NNP cord-015369-72cjogxz 7028 6 und und NNP cord-015369-72cjogxz 7028 7 nutritiven nutritiven NNP cord-015369-72cjogxz 7028 8 Konsequenzen Konsequenzen NNP cord-015369-72cjogxz 7028 9 gefürchtete gefürchtete NNP cord-015369-72cjogxz 7028 10 Komplikation Komplikation NNP cord-015369-72cjogxz 7028 11 . . . cord-015369-72cjogxz 7029 1 Die die VB cord-015369-72cjogxz 7029 2 optimale optimale NNP cord-015369-72cjogxz 7029 3 Therapie Therapie NNP cord-015369-72cjogxz 7029 4 -konservativ -konservativ JJ cord-015369-72cjogxz 7029 5 versus versus IN cord-015369-72cjogxz 7029 6 operativ operativ JJ cord-015369-72cjogxz 7029 7 -wird -wird HYPH cord-015369-72cjogxz 7029 8 kontrovers kontrovers NNP cord-015369-72cjogxz 7029 9 diskutiert diskutiert NNP cord-015369-72cjogxz 7029 10 . . . cord-015369-72cjogxz 7030 1 Chirurgische Chirurgische NNP cord-015369-72cjogxz 7030 2 Reinterventionen Reinterventionen NNP cord-015369-72cjogxz 7030 3 sind sind NNP cord-015369-72cjogxz 7030 4 häufig häufig NNP cord-015369-72cjogxz 7030 5 , , , cord-015369-72cjogxz 7030 6 neben neben NNP cord-015369-72cjogxz 7030 7 dem dem NNP cord-015369-72cjogxz 7030 8 nochmaligen nochmaligen NNP cord-015369-72cjogxz 7030 9 operativen operativen NNP cord-015369-72cjogxz 7030 10 Trauma Trauma NNP cord-015369-72cjogxz 7031 1 und und NNP cord-015369-72cjogxz 7032 1 einer einer NNP cord-015369-72cjogxz 7032 2 potentiellen potentiellen NNP cord-015369-72cjogxz 7032 3 Versagensrate Versagensrate NNP cord-015369-72cjogxz 7032 4 , , , cord-015369-72cjogxz 7032 5 mit mit NNP cord-015369-72cjogxz 7032 6 einer einer NNP cord-015369-72cjogxz 7033 1 erhöhten erhöhten NNP cord-015369-72cjogxz 7033 2 Morbidität Morbidität NNP cord-015369-72cjogxz 7033 3 und und IN cord-015369-72cjogxz 7033 4 Mortalität Mortalität NNP cord-015369-72cjogxz 7033 5 assoziiert assoziiert NN cord-015369-72cjogxz 7033 6 . . . cord-015369-72cjogxz 7034 1 Methodik Methodik NNP cord-015369-72cjogxz 7034 2 . . . cord-015369-72cjogxz 7035 1 Alle Alle NNP cord-015369-72cjogxz 7035 2 konsekutiven konsekutiven NNP cord-015369-72cjogxz 7035 3 Patienten Patienten NNP cord-015369-72cjogxz 7035 4 , , , cord-015369-72cjogxz 7035 5 die die VBP cord-015369-72cjogxz 7035 6 in in IN cord-015369-72cjogxz 7035 7 unserer unserer JJ cord-015369-72cjogxz 7035 8 Einrichtung Einrichtung NNP cord-015369-72cjogxz 7035 9 während während NNP cord-015369-72cjogxz 7035 10 eines eines NNP cord-015369-72cjogxz 7036 1 2-Jahreszeitraumes 2-jahreszeitraumes JJ cord-015369-72cjogxz 7036 2 eine eine NNP cord-015369-72cjogxz 7036 3 abdomino abdomino NN cord-015369-72cjogxz 7036 4 - - HYPH cord-015369-72cjogxz 7036 5 thorakale thorakale NNP cord-015369-72cjogxz 7036 6 Ö Ö NNP cord-015369-72cjogxz 7036 7 sophagusresektion sophagusresektion NNP cord-015369-72cjogxz 7036 8 wegen wegen NNP cord-015369-72cjogxz 7036 9 eines eines NNP cord-015369-72cjogxz 7036 10 Ö Ö NNP cord-015369-72cjogxz 7036 11 sophaguskarzinoms sophaguskarzinoms NNP cord-015369-72cjogxz 7036 12 erhielten erhielten NNP cord-015369-72cjogxz 7036 13 , , , cord-015369-72cjogxz 7036 14 wurden wurden NNP cord-015369-72cjogxz 7036 15 in in IN cord-015369-72cjogxz 7036 16 dieser dieser NNP cord-015369-72cjogxz 7036 17 Studie Studie NNP cord-015369-72cjogxz 7036 18 prospektiv prospektiv NNP cord-015369-72cjogxz 7036 19 erfasst erfasst NNP cord-015369-72cjogxz 7037 1 und und NNP cord-015369-72cjogxz 7038 1 i -PRON- PRP cord-015369-72cjogxz 7038 2 m be VBP cord-015369-72cjogxz 7038 3 Rahmen Rahmen NNP cord-015369-72cjogxz 7038 4 des des NNP cord-015369-72cjogxz 7038 5 internen internen NNP cord-015369-72cjogxz 7038 6 Qualitätsmanagements Qualitätsmanagements NNP cord-015369-72cjogxz 7038 7 auf auf NNP cord-015369-72cjogxz 7038 8 ihr ihr NNP cord-015369-72cjogxz 7038 9 Komplikationsspektrum Komplikationsspektrum NNP cord-015369-72cjogxz 7038 10 untersucht untersucht NN cord-015369-72cjogxz 7038 11 . . . cord-015369-72cjogxz 7039 1 Bei Bei NNP cord-015369-72cjogxz 7039 2 Diagnose diagnose VB cord-015369-72cjogxz 7039 3 eines eine NNS cord-015369-72cjogxz 7040 1 postoperativen postoperativen NNP cord-015369-72cjogxz 7040 2 Chylothorax Chylothorax NNP cord-015369-72cjogxz 7040 3 ' ' POS cord-015369-72cjogxz 7040 4 erfolgte erfolgte NN cord-015369-72cjogxz 7040 5 primär primär NN cord-015369-72cjogxz 7040 6 die die VBP cord-015369-72cjogxz 7040 7 konservative konservative JJ cord-015369-72cjogxz 7040 8 Therapie Therapie NNP cord-015369-72cjogxz 7040 9 entsprechend entsprechend NNP cord-015369-72cjogxz 7040 10 eines eines NNP cord-015369-72cjogxz 7041 1 an an DT cord-015369-72cjogxz 7041 2 unserer unserer JJ cord-015369-72cjogxz 7041 3 Einrichtung Einrichtung NNP cord-015369-72cjogxz 7041 4 inaugurierten inaugurierten JJ cord-015369-72cjogxz 7042 1 und und NNP cord-015369-72cjogxz 7042 2 etablierten etablierten NNP cord-015369-72cjogxz 7043 1 Therapiealgorithmus Therapiealgorithmus NNP cord-015369-72cjogxz 7043 2 ' ' '' cord-015369-72cjogxz 7043 3 . . . cord-015369-72cjogxz 7044 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 7044 2 . . . cord-015369-72cjogxz 7045 1 Von Von NNP cord-015369-72cjogxz 7045 2 Dezember Dezember NNP cord-015369-72cjogxz 7045 3 2006 2006 CD cord-015369-72cjogxz 7045 4 bis bis NN cord-015369-72cjogxz 7045 5 November November NNP cord-015369-72cjogxz 7045 6 2008 2008 CD cord-015369-72cjogxz 7046 1 unterzogen unterzogen NNP cord-015369-72cjogxz 7046 2 sich sich NNP cord-015369-72cjogxz 7047 1 56 56 CD cord-015369-72cjogxz 7047 2 Patienten Patienten NNP cord-015369-72cjogxz 7047 3 einer einer NNP cord-015369-72cjogxz 7047 4 subtotalen subtotalen NNP cord-015369-72cjogxz 7047 5 Ö Ö NNP cord-015369-72cjogxz 7047 6 sophagusresektion sophagusresektion NNP cord-015369-72cjogxz 7047 7 wegen wegen NNP cord-015369-72cjogxz 7047 8 eines eines NNP cord-015369-72cjogxz 7047 9 Ö Ö NNP cord-015369-72cjogxz 7047 10 sophaguskarzinoms sophaguskarzinom NNS cord-015369-72cjogxz 7047 11 . . . cord-015369-72cjogxz 7048 1 Insgesamt Insgesamt NNP cord-015369-72cjogxz 7048 2 drei drei NNP cord-015369-72cjogxz 7048 3 Patienten Patienten NNP cord-015369-72cjogxz 7048 4 entwickelten entwickelten VBD cord-015369-72cjogxz 7048 5 einen einen NNP cord-015369-72cjogxz 7048 6 postoperativen postoperativen VBN cord-015369-72cjogxz 7048 7 Chylothorax Chylothorax NNP cord-015369-72cjogxz 7048 8 , , , cord-015369-72cjogxz 7048 9 jeweils jeweils NNP cord-015369-72cjogxz 7048 10 rechtsthorakal rechtsthorakal RB cord-015369-72cjogxz 7048 11 . . . cord-015369-72cjogxz 7049 1 Dieser Dieser NNP cord-015369-72cjogxz 7049 2 konnte konnte NNP cord-015369-72cjogxz 7049 3 nach nach NNP cord-015369-72cjogxz 7049 4 klinischer klinischer NNP cord-015369-72cjogxz 7049 5 und und NNP cord-015369-72cjogxz 7050 1 laborchemischer laborchemischer NNP cord-015369-72cjogxz 7050 2 Diagnosebestätigung Diagnosebestätigung NNP cord-015369-72cjogxz 7051 1 ( ( -LRB- cord-015369-72cjogxz 7051 2 Detektion Detektion NNP cord-015369-72cjogxz 7051 3 von von NNP cord-015369-72cjogxz 7051 4 Chylomikronen Chylomikronen NNP cord-015369-72cjogxz 7051 5 , , , cord-015369-72cjogxz 7051 6 Triglyceridlevel Triglyceridlevel NNP cord-015369-72cjogxz 7052 1 > > XX cord-015369-72cjogxz 7053 1 110 110 CD cord-015369-72cjogxz 7053 2 mg mg NNP cord-015369-72cjogxz 7053 3 / / SYM cord-015369-72cjogxz 7053 4 dl dl NNP cord-015369-72cjogxz 7053 5 ) ) -RRB- cord-015369-72cjogxz 7053 6 in in IN cord-015369-72cjogxz 7053 7 allen allen NNP cord-015369-72cjogxz 7053 8 Fällen Fällen NNP cord-015369-72cjogxz 7053 9 erfolgreich erfolgreich NNP cord-015369-72cjogxz 7053 10 mittels mittels NNP cord-015369-72cjogxz 7053 11 ( ( -LRB- cord-015369-72cjogxz 7053 12 1 1 CD cord-015369-72cjogxz 7053 13 ) ) -RRB- cord-015369-72cjogxz 7053 14 totaler totaler NNP cord-015369-72cjogxz 7053 15 parenteraler parenteraler NNP cord-015369-72cjogxz 7053 16 Ernährung Ernährung NNP cord-015369-72cjogxz 7053 17 , , , cord-015369-72cjogxz 7053 18 ( ( -LRB- cord-015369-72cjogxz 7053 19 2 2 LS cord-015369-72cjogxz 7053 20 ) ) -RRB- cord-015369-72cjogxz 7053 21 Nahrungskarenz Nahrungskarenz NNP cord-015369-72cjogxz 7053 22 , , , cord-015369-72cjogxz 7053 23 ( ( -LRB- cord-015369-72cjogxz 7053 24 3 3 LS cord-015369-72cjogxz 7053 25 ) ) -RRB- cord-015369-72cjogxz 7054 1 pleuraler pleuraler NNP cord-015369-72cjogxz 7054 2 Drainage Drainage NNP cord-015369-72cjogxz 7054 3 sowie sowie NNP cord-015369-72cjogxz 7054 4 , , , cord-015369-72cjogxz 7054 5 ( ( -LRB- cord-015369-72cjogxz 7054 6 4 4 CD cord-015369-72cjogxz 7054 7 ) ) -RRB- cord-015369-72cjogxz 7054 8 subkutaner subkutaner NNP cord-015369-72cjogxz 7054 9 Octreotidgabe Octreotidgabe NNP cord-015369-72cjogxz 7054 10 , , , cord-015369-72cjogxz 7054 11 gefolgt gefolgt NNP cord-015369-72cjogxz 7054 12 von von NNP cord-015369-72cjogxz 7054 13 einer einer NNP cord-015369-72cjogxz 7054 14 , , , cord-015369-72cjogxz 7054 15 ( ( -LRB- cord-015369-72cjogxz 7054 16 5 5 LS cord-015369-72cjogxz 7054 17 ) ) -RRB- cord-015369-72cjogxz 7055 1 speziellen speziellen NNP cord-015369-72cjogxz 7055 2 oralen oralen NNP cord-015369-72cjogxz 7055 3 Diät Diät NNP cord-015369-72cjogxz 7056 1 ( ( -LRB- cord-015369-72cjogxz 7056 2 MCT MCT NNP cord-015369-72cjogxz 7056 3 - - HYPH cord-015369-72cjogxz 7056 4 Fette Fette NNP cord-015369-72cjogxz 7056 5 ) ) -RRB- cord-015369-72cjogxz 7056 6 therapiert therapiert NNP cord-015369-72cjogxz 7056 7 werden werden NNP cord-015369-72cjogxz 7056 8 . . . cord-015369-72cjogxz 7057 1 Die die VB cord-015369-72cjogxz 7057 2 mittlere mittlere RB cord-015369-72cjogxz 7058 1 Behandlungsdauer Behandlungsdauer NNP cord-015369-72cjogxz 7059 1 dieser dieser NNP cord-015369-72cjogxz 7059 2 konservativen konservativen NNP cord-015369-72cjogxz 7059 3 Therapie Therapie NNP cord-015369-72cjogxz 7059 4 betrug betrug NNP cord-015369-72cjogxz 7059 5 16 16 CD cord-015369-72cjogxz 7060 1 Tage Tage NNP cord-015369-72cjogxz 7060 2 . . . cord-015369-72cjogxz 7061 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 7061 2 . . . cord-015369-72cjogxz 7062 1 Beim Beim NNP cord-015369-72cjogxz 7062 2 Vorliegen Vorliegen NNP cord-015369-72cjogxz 7062 3 eines eine NNS cord-015369-72cjogxz 7063 1 postoperativen postoperativen NNP cord-015369-72cjogxz 7063 2 Chylothorax Chylothorax NNP cord-015369-72cjogxz 7063 3 ' ' POS cord-015369-72cjogxz 7063 4 sollte sollte NNP cord-015369-72cjogxz 7063 5 zunächst zunächst NNP cord-015369-72cjogxz 7063 6 konservativen konservativen NNP cord-015369-72cjogxz 7064 1 Therapiemaßnahmen therapiemaßnahmen NN cord-015369-72cjogxz 7064 2 i -PRON- PRP cord-015369-72cjogxz 7064 3 m be VBP cord-015369-72cjogxz 7064 4 Stufenschema Stufenschema NNP cord-015369-72cjogxz 7064 5 der der NN cord-015369-72cjogxz 7064 6 unbedingte unbedingte NN cord-015369-72cjogxz 7064 7 Vorzug Vorzug NNP cord-015369-72cjogxz 7064 8 gegeben gegeben NN cord-015369-72cjogxz 7064 9 und und XX cord-015369-72cjogxz 7065 1 diese diese NNP cord-015369-72cjogxz 7065 2 ausgeschöpft ausgeschöpft NNP cord-015369-72cjogxz 7065 3 werden werden NNP cord-015369-72cjogxz 7065 4 . . . cord-015369-72cjogxz 7066 1 Das Das NNP cord-015369-72cjogxz 7066 2 chirurgische chirurgische NN cord-015369-72cjogxz 7066 3 Vorgehen Vorgehen NNP cord-015369-72cjogxz 7067 1 hingegen hingegen NNP cord-015369-72cjogxz 7067 2 ist ist NNP cord-015369-72cjogxz 7067 3 frühzeitig frühzeitig NN cord-015369-72cjogxz 7067 4 bei bei NNP cord-015369-72cjogxz 7067 5 Versagen Versagen NNP cord-015369-72cjogxz 7068 1 konservativer konservativer NNP cord-015369-72cjogxz 7068 2 Therapien Therapien NNP cord-015369-72cjogxz 7068 3 sowie sowie NNP cord-015369-72cjogxz 7068 4 beim beim NNP cord-015369-72cjogxz 7068 5 Auftreten Auftreten NNP cord-015369-72cjogxz 7068 6 von von NNP cord-015369-72cjogxz 7068 7 Komplikationen Komplikationen NNP cord-015369-72cjogxz 7068 8 zu zu NNP cord-015369-72cjogxz 7068 9 favorisieren favorisieren NNP cord-015369-72cjogxz 7068 10 . . . cord-015369-72cjogxz 7069 1 Operability operability NN cord-015369-72cjogxz 7069 2 of of IN cord-015369-72cjogxz 7069 3 advanced advanced JJ cord-015369-72cjogxz 7069 4 central central JJ cord-015369-72cjogxz 7069 5 lung lung NN cord-015369-72cjogxz 7069 6 tumors tumor NNS cord-015369-72cjogxz 7069 7 usually usually RB cord-015369-72cjogxz 7069 8 is be VBZ cord-015369-72cjogxz 7069 9 limited limit VBN cord-015369-72cjogxz 7069 10 and and CC cord-015369-72cjogxz 7069 11 the the DT cord-015369-72cjogxz 7069 12 prognosis prognosis NN cord-015369-72cjogxz 7069 13 is be VBZ cord-015369-72cjogxz 7069 14 dismal dismal JJ cord-015369-72cjogxz 7069 15 . . . cord-015369-72cjogxz 7070 1 However however RB cord-015369-72cjogxz 7070 2 , , , cord-015369-72cjogxz 7070 3 combination combination NN cord-015369-72cjogxz 7070 4 of of IN cord-015369-72cjogxz 7070 5 chemoradio chemoradio NNP cord-015369-72cjogxz 7070 6 induction induction NN cord-015369-72cjogxz 7070 7 therapy therapy NN cord-015369-72cjogxz 7070 8 owns own VBZ cord-015369-72cjogxz 7070 9 the the DT cord-015369-72cjogxz 7070 10 potential potential NN cord-015369-72cjogxz 7070 11 for for IN cord-015369-72cjogxz 7070 12 significant significant JJ cord-015369-72cjogxz 7070 13 downs down NNS cord-015369-72cjogxz 7070 14 taging taging NN cord-015369-72cjogxz 7070 15 of of IN cord-015369-72cjogxz 7070 16 the the DT cord-015369-72cjogxz 7070 17 tumor tumor NN cord-015369-72cjogxz 7070 18 and and CC cord-015369-72cjogxz 7070 19 can can MD cord-015369-72cjogxz 7070 20 bring bring VB cord-015369-72cjogxz 7070 21 the the DT cord-015369-72cjogxz 7070 22 patient patient NN cord-015369-72cjogxz 7070 23 back back RB cord-015369-72cjogxz 7070 24 to to IN cord-015369-72cjogxz 7070 25 operability operability NN cord-015369-72cjogxz 7070 26 , , , cord-015369-72cjogxz 7070 27 even even RB cord-015369-72cjogxz 7070 28 in in IN cord-015369-72cjogxz 7070 29 advanced advanced JJ cord-015369-72cjogxz 7070 30 tumor tumor NN cord-015369-72cjogxz 7070 31 situations situation NNS cord-015369-72cjogxz 7070 32 . . . cord-015369-72cjogxz 7071 1 We -PRON- PRP cord-015369-72cjogxz 7071 2 present present VBP cord-015369-72cjogxz 7071 3 the the DT cord-015369-72cjogxz 7071 4 case case NN cord-015369-72cjogxz 7071 5 of of IN cord-015369-72cjogxz 7071 6 a a DT cord-015369-72cjogxz 7071 7 54 54 CD cord-015369-72cjogxz 7071 8 years year NNS cord-015369-72cjogxz 7071 9 old old JJ cord-015369-72cjogxz 7071 10 patient patient NN cord-015369-72cjogxz 7071 11 with with IN cord-015369-72cjogxz 7071 12 NSCLC NSCLC NNP cord-015369-72cjogxz 7071 13 ( ( -LRB- cord-015369-72cjogxz 7071 14 T4 T4 NNP cord-015369-72cjogxz 7071 15 , , , cord-015369-72cjogxz 7071 16 N2 N2 NNP cord-015369-72cjogxz 7071 17 , , , cord-015369-72cjogxz 7071 18 M0 m0 NN cord-015369-72cjogxz 7071 19 ; ; : cord-015369-72cjogxz 7071 20 stage stage NN cord-015369-72cjogxz 7071 21 IIIB IIIB NNP cord-015369-72cjogxz 7071 22 ) ) -RRB- cord-015369-72cjogxz 7071 23 of of IN cord-015369-72cjogxz 7071 24 the the DT cord-015369-72cjogxz 7071 25 right right JJ cord-015369-72cjogxz 7071 26 upper upper JJ cord-015369-72cjogxz 7071 27 lobe lobe NN cord-015369-72cjogxz 7071 28 and and CC cord-015369-72cjogxz 7071 29 infiltration infiltration NN cord-015369-72cjogxz 7071 30 of of IN cord-015369-72cjogxz 7071 31 the the DT cord-015369-72cjogxz 7071 32 carina carina NNP cord-015369-72cjogxz 7071 33 . . . cord-015369-72cjogxz 7072 1 Induction induction NN cord-015369-72cjogxz 7072 2 therapy therapy NN cord-015369-72cjogxz 7072 3 with with IN cord-015369-72cjogxz 7072 4 4 4 CD cord-015369-72cjogxz 7072 5 cycles cycle NNS cord-015369-72cjogxz 7072 6 of of IN cord-015369-72cjogxz 7072 7 Gemzar Gemzar NNP cord-015369-72cjogxz 7072 8 and and CC cord-015369-72cjogxz 7072 9 Cisplatin Cisplatin NNP cord-015369-72cjogxz 7072 10 combined combine VBN cord-015369-72cjogxz 7072 11 with with IN cord-015369-72cjogxz 7072 12 30 30 CD cord-015369-72cjogxz 7072 13 Gy Gy NNP cord-015369-72cjogxz 7072 14 local local JJ cord-015369-72cjogxz 7072 15 mediastinal mediastinal JJ cord-015369-72cjogxz 7072 16 radiation radiation NN cord-015369-72cjogxz 7072 17 resulted result VBD cord-015369-72cjogxz 7072 18 in in IN cord-015369-72cjogxz 7072 19 a a DT cord-015369-72cjogxz 7072 20 major major JJ cord-015369-72cjogxz 7072 21 clinical clinical JJ cord-015369-72cjogxz 7072 22 response response NN cord-015369-72cjogxz 7072 23 ( ( -LRB- cord-015369-72cjogxz 7072 24 yT3 yT3 NNP cord-015369-72cjogxz 7072 25 , , , cord-015369-72cjogxz 7072 26 yN0 yn0 NN cord-015369-72cjogxz 7072 27 , , , cord-015369-72cjogxz 7072 28 M0 m0 NN cord-015369-72cjogxz 7072 29 ; ; : cord-015369-72cjogxz 7072 30 stage stage NN cord-015369-72cjogxz 7072 31 IIB IIB NNP cord-015369-72cjogxz 7072 32 ) ) -RRB- cord-015369-72cjogxz 7072 33 . . . cord-015369-72cjogxz 7073 1 This this DT cord-015369-72cjogxz 7073 2 was be VBD cord-015369-72cjogxz 7073 3 followed follow VBN cord-015369-72cjogxz 7073 4 by by IN cord-015369-72cjogxz 7073 5 surgical surgical JJ cord-015369-72cjogxz 7073 6 resection resection NN cord-015369-72cjogxz 7073 7 ( ( -LRB- cord-015369-72cjogxz 7073 8 upper upper JJ cord-015369-72cjogxz 7073 9 bi bi JJ cord-015369-72cjogxz 7073 10 - - NN cord-015369-72cjogxz 7073 11 lobectomy lobectomy NN cord-015369-72cjogxz 7073 12 , , , cord-015369-72cjogxz 7073 13 resection resection NN cord-015369-72cjogxz 7073 14 of of IN cord-015369-72cjogxz 7073 15 the the DT cord-015369-72cjogxz 7073 16 carina carina NNP cord-015369-72cjogxz 7073 17 , , , cord-015369-72cjogxz 7073 18 end end VBP cord-015369-72cjogxz 7073 19 to to TO cord-015369-72cjogxz 7073 20 end end VB cord-015369-72cjogxz 7073 21 anastomosis anastomosis NN cord-015369-72cjogxz 7073 22 of of IN cord-015369-72cjogxz 7073 23 the the DT cord-015369-72cjogxz 7073 24 left left JJ cord-015369-72cjogxz 7073 25 main main JJ cord-015369-72cjogxz 7073 26 bronchus bronchus NN cord-015369-72cjogxz 7073 27 into into IN cord-015369-72cjogxz 7073 28 the the DT cord-015369-72cjogxz 7073 29 trachea trachea NN cord-015369-72cjogxz 7073 30 , , , cord-015369-72cjogxz 7073 31 re re NN cord-015369-72cjogxz 7073 32 - - NN cord-015369-72cjogxz 7073 33 implantation implantation NN cord-015369-72cjogxz 7073 34 of of IN cord-015369-72cjogxz 7073 35 the the DT cord-015369-72cjogxz 7073 36 right right JJ cord-015369-72cjogxz 7073 37 lower low JJR cord-015369-72cjogxz 7073 38 lobe lobe NN cord-015369-72cjogxz 7073 39 into into IN cord-015369-72cjogxz 7073 40 the the DT cord-015369-72cjogxz 7073 41 left left JJ cord-015369-72cjogxz 7073 42 main main JJ cord-015369-72cjogxz 7073 43 bronchus bronchus NN cord-015369-72cjogxz 7073 44 ; ; : cord-015369-72cjogxz 7073 45 all all DT cord-015369-72cjogxz 7073 46 performed perform VBN cord-015369-72cjogxz 7073 47 under under IN cord-015369-72cjogxz 7073 48 temporary temporary JJ cord-015369-72cjogxz 7073 49 ECMO ECMO NNP cord-015369-72cjogxz 7073 50 support support NN cord-015369-72cjogxz 7073 51 ) ) -RRB- cord-015369-72cjogxz 7073 52 . . . cord-015369-72cjogxz 7074 1 Pathological pathological JJ cord-015369-72cjogxz 7074 2 investigation investigation NN cord-015369-72cjogxz 7074 3 revealed reveal VBD cord-015369-72cjogxz 7074 4 a a DT cord-015369-72cjogxz 7074 5 complete complete JJ cord-015369-72cjogxz 7074 6 response response NN cord-015369-72cjogxz 7074 7 with with IN cord-015369-72cjogxz 7074 8 no no DT cord-015369-72cjogxz 7074 9 vital vital JJ cord-015369-72cjogxz 7074 10 tumor tumor NN cord-015369-72cjogxz 7074 11 cells cell NNS cord-015369-72cjogxz 7074 12 left leave VBD cord-015369-72cjogxz 7074 13 . . . cord-015369-72cjogxz 7075 1 This this DT cord-015369-72cjogxz 7075 2 report report NN cord-015369-72cjogxz 7075 3 demonstrates demonstrate VBZ cord-015369-72cjogxz 7075 4 the the DT cord-015369-72cjogxz 7075 5 potentials potential NNS cord-015369-72cjogxz 7075 6 of of IN cord-015369-72cjogxz 7075 7 modern modern JJ cord-015369-72cjogxz 7075 8 combination combination NN cord-015369-72cjogxz 7075 9 therapy therapy NN cord-015369-72cjogxz 7075 10 of of IN cord-015369-72cjogxz 7075 11 extended extended JJ cord-015369-72cjogxz 7075 12 lung lung NN cord-015369-72cjogxz 7075 13 tumors tumor NNS cord-015369-72cjogxz 7075 14 , , , cord-015369-72cjogxz 7075 15 emphasizing emphasize VBG cord-015369-72cjogxz 7075 16 the the DT cord-015369-72cjogxz 7075 17 value value NN cord-015369-72cjogxz 7075 18 of of IN cord-015369-72cjogxz 7075 19 aggressive aggressive JJ cord-015369-72cjogxz 7075 20 induction induction NN cord-015369-72cjogxz 7075 21 therapy therapy NN cord-015369-72cjogxz 7075 22 , , , cord-015369-72cjogxz 7075 23 followed follow VBN cord-015369-72cjogxz 7075 24 by by IN cord-015369-72cjogxz 7075 25 a a DT cord-015369-72cjogxz 7075 26 technically technically RB cord-015369-72cjogxz 7075 27 demanding demanding JJ cord-015369-72cjogxz 7075 28 operation operation NN cord-015369-72cjogxz 7075 29 , , , cord-015369-72cjogxz 7075 30 in in IN cord-015369-72cjogxz 7075 31 case case NN cord-015369-72cjogxz 7075 32 of of IN cord-015369-72cjogxz 7075 33 good good JJ cord-015369-72cjogxz 7075 34 clinical clinical JJ cord-015369-72cjogxz 7075 35 response response NN cord-015369-72cjogxz 7075 36 . . . cord-015369-72cjogxz 7076 1 Response response NN cord-015369-72cjogxz 7076 2 to to IN cord-015369-72cjogxz 7076 3 induction induction NN cord-015369-72cjogxz 7076 4 therapy therapy NN cord-015369-72cjogxz 7076 5 , , , cord-015369-72cjogxz 7076 6 together together RB cord-015369-72cjogxz 7076 7 with with IN cord-015369-72cjogxz 7076 8 completeness completeness NN cord-015369-72cjogxz 7076 9 of of IN cord-015369-72cjogxz 7076 10 surgical surgical JJ cord-015369-72cjogxz 7076 11 resection resection NN cord-015369-72cjogxz 7076 12 , , , cord-015369-72cjogxz 7076 13 remains remain VBZ cord-015369-72cjogxz 7076 14 the the DT cord-015369-72cjogxz 7076 15 most most RBS cord-015369-72cjogxz 7076 16 significant significant JJ cord-015369-72cjogxz 7076 17 prognostic prognostic JJ cord-015369-72cjogxz 7076 18 parameters parameter NNS cord-015369-72cjogxz 7076 19 for for IN cord-015369-72cjogxz 7076 20 outcome outcome NN cord-015369-72cjogxz 7076 21 . . . cord-015369-72cjogxz 7077 1 Keywords Keywords NNPS cord-015369-72cjogxz 7077 2 . . . cord-015369-72cjogxz 7078 1 NSCLC NSCLC NNP cord-015369-72cjogxz 7078 2 , , , cord-015369-72cjogxz 7078 3 carinal carinal JJ cord-015369-72cjogxz 7078 4 resection resection NN cord-015369-72cjogxz 7078 5 , , , cord-015369-72cjogxz 7078 6 ECMO ECMO NNP cord-015369-72cjogxz 7078 7 , , , cord-015369-72cjogxz 7079 1 neoadjuvant neoadjuvant JJ cord-015369-72cjogxz 7079 2 chemo chemo NN cord-015369-72cjogxz 7079 3 - - HYPH cord-015369-72cjogxz 7079 4 radiotherapy radiotherapy NN cord-015369-72cjogxz 7079 5 , , , cord-015369-72cjogxz 7079 6 complete complete JJ cord-015369-72cjogxz 7079 7 response response NN cord-015369-72cjogxz 7079 8 . . . cord-015369-72cjogxz 7080 1 Pulmonary pulmonary JJ cord-015369-72cjogxz 7080 2 benign benign JJ cord-015369-72cjogxz 7080 3 metastasizing metastasize VBG cord-015369-72cjogxz 7080 4 Leiomyomatosis Leiomyomatosis NNP cord-015369-72cjogxz 7080 5 ( ( -LRB- cord-015369-72cjogxz 7080 6 BML BML NNP cord-015369-72cjogxz 7080 7 ) ) -RRB- cord-015369-72cjogxz 7080 8 is be VBZ cord-015369-72cjogxz 7080 9 a a DT cord-015369-72cjogxz 7080 10 rare rare JJ cord-015369-72cjogxz 7080 11 smooth smooth JJ cord-015369-72cjogxz 7080 12 muscle muscle NN cord-015369-72cjogxz 7080 13 cell cell NN cord-015369-72cjogxz 7080 14 disorder disorder NN cord-015369-72cjogxz 7080 15 of of IN cord-015369-72cjogxz 7080 16 the the DT cord-015369-72cjogxz 7080 17 lung lung NN cord-015369-72cjogxz 7080 18 . . . cord-015369-72cjogxz 7081 1 The the DT cord-015369-72cjogxz 7081 2 prevailing prevail VBG cord-015369-72cjogxz 7081 3 treatment treatment NN cord-015369-72cjogxz 7081 4 option option NN cord-015369-72cjogxz 7081 5 is be VBZ cord-015369-72cjogxz 7081 6 a a DT cord-015369-72cjogxz 7081 7 primary primary JJ cord-015369-72cjogxz 7081 8 excision excision NN cord-015369-72cjogxz 7081 9 of of IN cord-015369-72cjogxz 7081 10 the the DT cord-015369-72cjogxz 7081 11 nodules nodule NNS cord-015369-72cjogxz 7081 12 or or CC cord-015369-72cjogxz 7081 13 if if IN cord-015369-72cjogxz 7081 14 unresectable unresectable JJ cord-015369-72cjogxz 7081 15 a a DT cord-015369-72cjogxz 7081 16 long long JJ cord-015369-72cjogxz 7081 17 - - HYPH cord-015369-72cjogxz 7081 18 time time NN cord-015369-72cjogxz 7081 19 hormone hormone NN cord-015369-72cjogxz 7081 20 therapy therapy NN cord-015369-72cjogxz 7081 21 . . . cord-015369-72cjogxz 7082 1 Herein herein RB cord-015369-72cjogxz 7082 2 , , , cord-015369-72cjogxz 7082 3 we -PRON- PRP cord-015369-72cjogxz 7082 4 present present VBP cord-015369-72cjogxz 7082 5 a a DT cord-015369-72cjogxz 7082 6 case case NN cord-015369-72cjogxz 7082 7 of of IN cord-015369-72cjogxz 7082 8 BML BML NNP cord-015369-72cjogxz 7082 9 in in IN cord-015369-72cjogxz 7082 10 which which WDT cord-015369-72cjogxz 7082 11 a a DT cord-015369-72cjogxz 7082 12 wait wait VB cord-015369-72cjogxz 7082 13 - - HYPH cord-015369-72cjogxz 7082 14 and and CC cord-015369-72cjogxz 7082 15 - - HYPH cord-015369-72cjogxz 7082 16 see see VB cord-015369-72cjogxz 7082 17 strategy strategy NN cord-015369-72cjogxz 7082 18 after after IN cord-015369-72cjogxz 7082 19 diagnosis diagnosis NN cord-015369-72cjogxz 7082 20 has have VBZ cord-015369-72cjogxz 7082 21 been be VBN cord-015369-72cjogxz 7082 22 decided decide VBN cord-015369-72cjogxz 7082 23 . . . cord-015369-72cjogxz 7083 1 A a DT cord-015369-72cjogxz 7083 2 56-year 56-year JJ cord-015369-72cjogxz 7083 3 - - HYPH cord-015369-72cjogxz 7083 4 old old JJ cord-015369-72cjogxz 7083 5 female female NN cord-015369-72cjogxz 7083 6 was be VBD cord-015369-72cjogxz 7083 7 admitted admit VBN cord-015369-72cjogxz 7083 8 to to IN cord-015369-72cjogxz 7083 9 the the DT cord-015369-72cjogxz 7083 10 Medical Medical NNP cord-015369-72cjogxz 7083 11 University University NNP cord-015369-72cjogxz 7083 12 of of IN cord-015369-72cjogxz 7083 13 Vienna Vienna NNP cord-015369-72cjogxz 7083 14 presenting present VBG cord-015369-72cjogxz 7083 15 with with IN cord-015369-72cjogxz 7083 16 multiple multiple JJ cord-015369-72cjogxz 7083 17 , , , cord-015369-72cjogxz 7083 18 bilateral bilateral JJ cord-015369-72cjogxz 7083 19 suspect suspect JJ cord-015369-72cjogxz 7083 20 pulmonary pulmonary JJ cord-015369-72cjogxz 7083 21 tumor tumor NN cord-015369-72cjogxz 7083 22 masses masse NNS cord-015369-72cjogxz 7083 23 in in IN cord-015369-72cjogxz 7083 24 1993 1993 CD cord-015369-72cjogxz 7083 25 . . . cord-015369-72cjogxz 7084 1 Subsequent subsequent JJ cord-015369-72cjogxz 7084 2 diagnostic diagnostic JJ cord-015369-72cjogxz 7084 3 workup workup NN cord-015369-72cjogxz 7084 4 revealed reveal VBD cord-015369-72cjogxz 7084 5 a a DT cord-015369-72cjogxz 7084 6 BML BML NNP cord-015369-72cjogxz 7084 7 . . . cord-015369-72cjogxz 7085 1 The the DT cord-015369-72cjogxz 7085 2 patient patient NN cord-015369-72cjogxz 7085 3 refused refuse VBD cord-015369-72cjogxz 7085 4 a a DT cord-015369-72cjogxz 7085 5 surgical surgical JJ cord-015369-72cjogxz 7085 6 intervention intervention NN cord-015369-72cjogxz 7085 7 and and CC cord-015369-72cjogxz 7085 8 hormone hormone NN cord-015369-72cjogxz 7085 9 treatment treatment NN cord-015369-72cjogxz 7085 10 was be VBD cord-015369-72cjogxz 7085 11 abandoned abandon VBN cord-015369-72cjogxz 7085 12 because because IN cord-015369-72cjogxz 7085 13 of of IN cord-015369-72cjogxz 7085 14 the the DT cord-015369-72cjogxz 7085 15 patient patient NN cord-015369-72cjogxz 7085 16 's 's POS cord-015369-72cjogxz 7085 17 heavy heavy JJ cord-015369-72cjogxz 7085 18 menopausal menopausal JJ cord-015369-72cjogxz 7085 19 disorders disorder NNS cord-015369-72cjogxz 7085 20 . . . cord-015369-72cjogxz 7086 1 As as IN cord-015369-72cjogxz 7086 2 malign malign JJ cord-015369-72cjogxz 7086 3 transformation transformation NN cord-015369-72cjogxz 7086 4 of of IN cord-015369-72cjogxz 7086 5 BML BML NNP cord-015369-72cjogxz 7086 6 is be VBZ cord-015369-72cjogxz 7086 7 uncommon uncommon JJ cord-015369-72cjogxz 7086 8 a a DT cord-015369-72cjogxz 7086 9 wait wait VB cord-015369-72cjogxz 7086 10 - - HYPH cord-015369-72cjogxz 7086 11 and and CC cord-015369-72cjogxz 7086 12 - - HYPH cord-015369-72cjogxz 7086 13 see see VB cord-015369-72cjogxz 7086 14 strategy strategy NN cord-015369-72cjogxz 7086 15 was be VBD cord-015369-72cjogxz 7086 16 agreed agree VBN cord-015369-72cjogxz 7086 17 upon upon IN cord-015369-72cjogxz 7086 18 . . . cord-015369-72cjogxz 7087 1 However however RB cord-015369-72cjogxz 7087 2 , , , cord-015369-72cjogxz 7087 3 the the DT cord-015369-72cjogxz 7087 4 patient patient NN cord-015369-72cjogxz 7087 5 was be VBD cord-015369-72cjogxz 7087 6 lost lose VBN cord-015369-72cjogxz 7087 7 to to TO cord-015369-72cjogxz 7087 8 follow follow VB cord-015369-72cjogxz 7087 9 - - HYPH cord-015369-72cjogxz 7087 10 up up NN cord-015369-72cjogxz 7087 11 , , , cord-015369-72cjogxz 7087 12 until until IN cord-015369-72cjogxz 7087 13 in in IN cord-015369-72cjogxz 7087 14 2007 2007 CD cord-015369-72cjogxz 7087 15 , , , cord-015369-72cjogxz 7087 16 14 14 CD cord-015369-72cjogxz 7087 17 years year NNS cord-015369-72cjogxz 7087 18 later later RB cord-015369-72cjogxz 7087 19 , , , cord-015369-72cjogxz 7087 20 she -PRON- PRP cord-015369-72cjogxz 7087 21 developed develop VBD cord-015369-72cjogxz 7087 22 expiratory expiratory NNP cord-015369-72cjogxz 7087 23 rhonchus rhonchu NNS cord-015369-72cjogxz 7087 24 . . . cord-015369-72cjogxz 7088 1 A a DT cord-015369-72cjogxz 7088 2 thoracic thoracic JJ cord-015369-72cjogxz 7088 3 - - HYPH cord-015369-72cjogxz 7088 4 CT CT NNP cord-015369-72cjogxz 7088 5 revealed reveal VBD cord-015369-72cjogxz 7088 6 eleven eleven CD cord-015369-72cjogxz 7088 7 intrapulmonary intrapulmonary JJ cord-015369-72cjogxz 7088 8 circumscribed circumscribed JJ cord-015369-72cjogxz 7088 9 circular circular JJ cord-015369-72cjogxz 7088 10 foci foci NN cord-015369-72cjogxz 7088 11 . . . cord-015369-72cjogxz 7089 1 In in IN cord-015369-72cjogxz 7089 2 addition addition NN cord-015369-72cjogxz 7089 3 the the DT cord-015369-72cjogxz 7089 4 left left JJ cord-015369-72cjogxz 7089 5 lower low JJR cord-015369-72cjogxz 7089 6 - - HYPH cord-015369-72cjogxz 7089 7 third third NN cord-015369-72cjogxz 7089 8 was be VBD cord-015369-72cjogxz 7089 9 filled fill VBN cord-015369-72cjogxz 7089 10 up up RP cord-015369-72cjogxz 7089 11 with with IN cord-015369-72cjogxz 7089 12 tumor tumor NN cord-015369-72cjogxz 7089 13 mass mass NN cord-015369-72cjogxz 7089 14 and and CC cord-015369-72cjogxz 7089 15 a a DT cord-015369-72cjogxz 7089 16 giant giant JJ cord-015369-72cjogxz 7089 17 cyst cyst NN cord-015369-72cjogxz 7089 18 ( ( -LRB- cord-015369-72cjogxz 7089 19 diameter diameter NN cord-015369-72cjogxz 7089 20 18 18 CD cord-015369-72cjogxz 7089 21 cm cm NNS cord-015369-72cjogxz 7089 22 ) ) -RRB- cord-015369-72cjogxz 7089 23 extended extend VBD cord-015369-72cjogxz 7089 24 into into IN cord-015369-72cjogxz 7089 25 the the DT cord-015369-72cjogxz 7089 26 thoracic thoracic JJ cord-015369-72cjogxz 7089 27 cave cave NN cord-015369-72cjogxz 7089 28 . . . cord-015369-72cjogxz 7090 1 The the DT cord-015369-72cjogxz 7090 2 nodules nodule NNS cord-015369-72cjogxz 7090 3 and and CC cord-015369-72cjogxz 7090 4 the the DT cord-015369-72cjogxz 7090 5 tumor tumor NN cord-015369-72cjogxz 7090 6 mass mass NN cord-015369-72cjogxz 7090 7 were be VBD cord-015369-72cjogxz 7090 8 excised excise VBN cord-015369-72cjogxz 7090 9 and and CC cord-015369-72cjogxz 7090 10 the the DT cord-015369-72cjogxz 7090 11 patient patient NN cord-015369-72cjogxz 7090 12 fully fully RB cord-015369-72cjogxz 7090 13 recovered recover VBD cord-015369-72cjogxz 7090 14 without without IN cord-015369-72cjogxz 7090 15 any any DT cord-015369-72cjogxz 7090 16 evidence evidence NN cord-015369-72cjogxz 7090 17 of of IN cord-015369-72cjogxz 7090 18 a a DT cord-015369-72cjogxz 7090 19 remaining remain VBG cord-015369-72cjogxz 7090 20 disease disease NN cord-015369-72cjogxz 7090 21 . . . cord-015369-72cjogxz 7091 1 Pulmonary pulmonary JJ cord-015369-72cjogxz 7091 2 BML BML NNP cord-015369-72cjogxz 7091 3 nodules nodule NNS cord-015369-72cjogxz 7091 4 have have VBP cord-015369-72cjogxz 7091 5 been be VBN cord-015369-72cjogxz 7091 6 shown show VBN cord-015369-72cjogxz 7091 7 to to TO cord-015369-72cjogxz 7091 8 stay stay VB cord-015369-72cjogxz 7091 9 constant constant JJ cord-015369-72cjogxz 7091 10 for for IN cord-015369-72cjogxz 7091 11 a a DT cord-015369-72cjogxz 7091 12 long long JJ cord-015369-72cjogxz 7091 13 time time NN cord-015369-72cjogxz 7091 14 . . . cord-015369-72cjogxz 7092 1 If if IN cord-015369-72cjogxz 7092 2 resectable resectable NNP cord-015369-72cjogxz 7092 3 , , , cord-015369-72cjogxz 7092 4 a a DT cord-015369-72cjogxz 7092 5 surgical surgical JJ cord-015369-72cjogxz 7092 6 excision excision NN cord-015369-72cjogxz 7092 7 is be VBZ cord-015369-72cjogxz 7092 8 recommended recommend VBN cord-015369-72cjogxz 7092 9 as as IN cord-015369-72cjogxz 7092 10 first first JJ cord-015369-72cjogxz 7092 11 line line NN cord-015369-72cjogxz 7092 12 therapy therapy NN cord-015369-72cjogxz 7092 13 . . . cord-015369-72cjogxz 7093 1 Our -PRON- PRP$ cord-015369-72cjogxz 7093 2 case case NN cord-015369-72cjogxz 7093 3 report report NN cord-015369-72cjogxz 7093 4 indicates indicate VBZ cord-015369-72cjogxz 7093 5 that that IN cord-015369-72cjogxz 7093 6 a a DT cord-015369-72cjogxz 7093 7 wait wait VB cord-015369-72cjogxz 7093 8 - - HYPH cord-015369-72cjogxz 7093 9 and and CC cord-015369-72cjogxz 7093 10 - - HYPH cord-015369-72cjogxz 7093 11 see see VB cord-015369-72cjogxz 7093 12 strategy strategy NN cord-015369-72cjogxz 7093 13 is be VBZ cord-015369-72cjogxz 7093 14 feasible feasible JJ cord-015369-72cjogxz 7093 15 but but CC cord-015369-72cjogxz 7093 16 could could MD cord-015369-72cjogxz 7093 17 lead lead VB cord-015369-72cjogxz 7093 18 to to IN cord-015369-72cjogxz 7093 19 severe severe JJ cord-015369-72cjogxz 7093 20 complications complication NNS cord-015369-72cjogxz 7093 21 . . . cord-015369-72cjogxz 7094 1 We -PRON- PRP cord-015369-72cjogxz 7094 2 therefore therefore RB cord-015369-72cjogxz 7094 3 conclude conclude VBP cord-015369-72cjogxz 7094 4 that that IN cord-015369-72cjogxz 7094 5 a a DT cord-015369-72cjogxz 7094 6 primary primary JJ cord-015369-72cjogxz 7094 7 excision excision NN cord-015369-72cjogxz 7094 8 of of IN cord-015369-72cjogxz 7094 9 BML BML NNP cord-015369-72cjogxz 7094 10 tumor tumor NN cord-015369-72cjogxz 7094 11 masses masse NNS cord-015369-72cjogxz 7094 12 is be VBZ cord-015369-72cjogxz 7094 13 preferable preferable JJ cord-015369-72cjogxz 7094 14 in in IN cord-015369-72cjogxz 7094 15 order order NN cord-015369-72cjogxz 7094 16 to to TO cord-015369-72cjogxz 7094 17 avoid avoid VB cord-015369-72cjogxz 7094 18 complications complication NNS cord-015369-72cjogxz 7094 19 leading lead VBG cord-015369-72cjogxz 7094 20 to to IN cord-015369-72cjogxz 7094 21 more more JJR cord-015369-72cjogxz 7094 22 extended extended JJ cord-015369-72cjogxz 7094 23 surgical surgical JJ cord-015369-72cjogxz 7094 24 interventions intervention NNS cord-015369-72cjogxz 7094 25 . . . cord-015369-72cjogxz 7095 1 Background background NN cord-015369-72cjogxz 7095 2 . . . cord-015369-72cjogxz 7096 1 Pulmonary pulmonary JJ cord-015369-72cjogxz 7096 2 re re NN cord-015369-72cjogxz 7096 3 - - NN cord-015369-72cjogxz 7096 4 transplantation transplantation NN cord-015369-72cjogxz 7096 5 ( ( -LRB- cord-015369-72cjogxz 7096 6 PRT PRT NNP cord-015369-72cjogxz 7096 7 ) ) -RRB- cord-015369-72cjogxz 7096 8 remains remain VBZ cord-015369-72cjogxz 7096 9 the the DT cord-015369-72cjogxz 7096 10 only only JJ cord-015369-72cjogxz 7096 11 therapeutic therapeutic JJ cord-015369-72cjogxz 7096 12 option option NN cord-015369-72cjogxz 7096 13 in in IN cord-015369-72cjogxz 7096 14 some some DT cord-015369-72cjogxz 7096 15 cases case NNS cord-015369-72cjogxz 7096 16 of of IN cord-015369-72cjogxz 7096 17 severe severe JJ cord-015369-72cjogxz 7096 18 primary primary JJ cord-015369-72cjogxz 7096 19 graft graft NN cord-015369-72cjogxz 7096 20 dysfunction dysfunction NN cord-015369-72cjogxz 7096 21 ( ( -LRB- cord-015369-72cjogxz 7096 22 PGD PGD NNP cord-015369-72cjogxz 7096 23 ) ) -RRB- cord-015369-72cjogxz 7096 24 , , , cord-015369-72cjogxz 7096 25 advanced advanced JJ cord-015369-72cjogxz 7096 26 bronchiolitis bronchiolitis NNP cord-015369-72cjogxz 7096 27 obliterans obliterans NNP cord-015369-72cjogxz 7096 28 sydrome sydrome NNP cord-015369-72cjogxz 7096 29 ( ( -LRB- cord-015369-72cjogxz 7096 30 BOS BOS NNP cord-015369-72cjogxz 7096 31 ) ) -RRB- cord-015369-72cjogxz 7096 32 , , , cord-015369-72cjogxz 7096 33 and and CC cord-015369-72cjogxz 7096 34 in in IN cord-015369-72cjogxz 7096 35 some some DT cord-015369-72cjogxz 7096 36 cases case NNS cord-015369-72cjogxz 7096 37 of of IN cord-015369-72cjogxz 7096 38 severe severe JJ cord-015369-72cjogxz 7096 39 airway airway NN cord-015369-72cjogxz 7096 40 problems problem NNS cord-015369-72cjogxz 7096 41 ( ( -LRB- cord-015369-72cjogxz 7096 42 AWP AWP NNP cord-015369-72cjogxz 7096 43 ) ) -RRB- cord-015369-72cjogxz 7096 44 , , , cord-015369-72cjogxz 7096 45 mainly mainly RB cord-015369-72cjogxz 7096 46 cicatriceal cicatriceal JJ cord-015369-72cjogxz 7096 47 stenosis stenosis NN cord-015369-72cjogxz 7096 48 . . . cord-015369-72cjogxz 7097 1 However however RB cord-015369-72cjogxz 7097 2 , , , cord-015369-72cjogxz 7097 3 its -PRON- PRP$ cord-015369-72cjogxz 7097 4 value value NN cord-015369-72cjogxz 7097 5 has have VBZ cord-015369-72cjogxz 7097 6 been be VBN cord-015369-72cjogxz 7097 7 questioned question VBN cord-015369-72cjogxz 7097 8 due due IN cord-015369-72cjogxz 7097 9 to to IN cord-015369-72cjogxz 7097 10 the the DT cord-015369-72cjogxz 7097 11 overall overall JJ cord-015369-72cjogxz 7097 12 scarcity scarcity NN cord-015369-72cjogxz 7097 13 of of IN cord-015369-72cjogxz 7097 14 donor donor NN cord-015369-72cjogxz 7097 15 organs organ NNS cord-015369-72cjogxz 7097 16 and and CC cord-015369-72cjogxz 7097 17 reports report NNS cord-015369-72cjogxz 7097 18 indicating indicate VBG cord-015369-72cjogxz 7097 19 unsatisfactory unsatisfactory JJ cord-015369-72cjogxz 7097 20 outcome outcome NN cord-015369-72cjogxz 7097 21 . . . cord-015369-72cjogxz 7098 1 We -PRON- PRP cord-015369-72cjogxz 7098 2 analyzed analyze VBD cord-015369-72cjogxz 7098 3 our -PRON- PRP$ cord-015369-72cjogxz 7098 4 institutional institutional JJ cord-015369-72cjogxz 7098 5 experience experience NN cord-015369-72cjogxz 7098 6 with with IN cord-015369-72cjogxz 7098 7 PRT PRT NNP cord-015369-72cjogxz 7098 8 to to TO cord-015369-72cjogxz 7098 9 evaluate evaluate VB cord-015369-72cjogxz 7098 10 its -PRON- PRP$ cord-015369-72cjogxz 7098 11 value value NN cord-015369-72cjogxz 7098 12 for for IN cord-015369-72cjogxz 7098 13 different different JJ cord-015369-72cjogxz 7098 14 indications indication NNS cord-015369-72cjogxz 7098 15 . . . cord-015369-72cjogxz 7099 1 Methods method NNS cord-015369-72cjogxz 7099 2 . . . cord-015369-72cjogxz 7100 1 We -PRON- PRP cord-015369-72cjogxz 7100 2 retrospectively retrospectively RB cord-015369-72cjogxz 7100 3 analyzed analyze VBD cord-015369-72cjogxz 7100 4 all all DT cord-015369-72cjogxz 7100 5 46 46 CD cord-015369-72cjogxz 7100 6 patients patient NNS cord-015369-72cjogxz 7100 7 undergoing undergo VBG cord-015369-72cjogxz 7100 8 PRT PRT NNP cord-015369-72cjogxz 7100 9 in in IN cord-015369-72cjogxz 7100 10 our -PRON- PRP$ cord-015369-72cjogxz 7100 11 department department NN cord-015369-72cjogxz 7100 12 from from IN cord-015369-72cjogxz 7100 13 August August NNP cord-015369-72cjogxz 7100 14 1995 1995 CD cord-015369-72cjogxz 7100 15 to to IN cord-015369-72cjogxz 7100 16 August August NNP cord-015369-72cjogxz 7100 17 2006 2006 CD cord-015369-72cjogxz 7100 18 . . . cord-015369-72cjogxz 7101 1 We -PRON- PRP cord-015369-72cjogxz 7101 2 stratified stratify VBD cord-015369-72cjogxz 7101 3 patients patient NNS cord-015369-72cjogxz 7101 4 according accord VBG cord-015369-72cjogxz 7101 5 to to IN cord-015369-72cjogxz 7101 6 indication indication NN cord-015369-72cjogxz 7101 7 for for IN cord-015369-72cjogxz 7101 8 PRT PRT NNP cord-015369-72cjogxz 7101 9 and and CC cord-015369-72cjogxz 7101 10 analyzed analyze VBD cord-015369-72cjogxz 7101 11 the the DT cord-015369-72cjogxz 7101 12 outcome outcome NN cord-015369-72cjogxz 7101 13 . . . cord-015369-72cjogxz 7102 1 Results result NNS cord-015369-72cjogxz 7102 2 . . . cord-015369-72cjogxz 7103 1 Forty forty CD cord-015369-72cjogxz 7103 2 - - HYPH cord-015369-72cjogxz 7103 3 six six CD cord-015369-72cjogxz 7103 4 patients patient NNS cord-015369-72cjogxz 7103 5 ( ( -LRB- cord-015369-72cjogxz 7103 6 mean mean VB cord-015369-72cjogxz 7103 7 age age NN cord-015369-72cjogxz 7103 8 41 41 CD cord-015369-72cjogxz 7103 9 AE AE NNP cord-015369-72cjogxz 7103 10 16 16 CD cord-015369-72cjogxz 7103 11 years year NNS cord-015369-72cjogxz 7103 12 , , , cord-015369-72cjogxz 7103 13 18 18 CD cord-015369-72cjogxz 7103 14 male male NN cord-015369-72cjogxz 7103 15 and and CC cord-015369-72cjogxz 7103 16 28 28 CD cord-015369-72cjogxz 7103 17 female female JJ cord-015369-72cjogxz 7103 18 ) ) -RRB- cord-015369-72cjogxz 7103 19 underwent undergo VBD cord-015369-72cjogxz 7103 20 PRT PRT NNP cord-015369-72cjogxz 7103 21 ( ( -LRB- cord-015369-72cjogxz 7103 22 14 14 CD cord-015369-72cjogxz 7103 23 bilateral bilateral JJ cord-015369-72cjogxz 7103 24 lung lung NN cord-015369-72cjogxz 7103 25 - - HYPH cord-015369-72cjogxz 7103 26 transplantations transplantation NNS cord-015369-72cjogxz 7103 27 , , , cord-015369-72cjogxz 7103 28 32 32 CD cord-015369-72cjogxz 7103 29 single single JJ cord-015369-72cjogxz 7103 30 - - HYPH cord-015369-72cjogxz 7103 31 lung lung NN cord-015369-72cjogxz 7103 32 - - HYPH cord-015369-72cjogxz 7103 33 transplantations transplantation NNS cord-015369-72cjogxz 7103 34 ) ) -RRB- cord-015369-72cjogxz 7103 35 for for IN cord-015369-72cjogxz 7103 36 PGD PGD NNP cord-015369-72cjogxz 7103 37 ( ( -LRB- cord-015369-72cjogxz 7103 38 n n NN cord-015369-72cjogxz 7103 39 ¼ ¼ NNP cord-015369-72cjogxz 7103 40 23 23 CD cord-015369-72cjogxz 7103 41 ) ) -RRB- cord-015369-72cjogxz 7103 42 , , , cord-015369-72cjogxz 7103 43 BOS BOS NNP cord-015369-72cjogxz 7103 44 ( ( -LRB- cord-015369-72cjogxz 7103 45 n n NN cord-015369-72cjogxz 7103 46 ¼ ¼ NNP cord-015369-72cjogxz 7103 47 19 19 CD cord-015369-72cjogxz 7103 48 ) ) -RRB- cord-015369-72cjogxz 7103 49 and and CC cord-015369-72cjogxz 7103 50 AWP AWP NNP cord-015369-72cjogxz 7103 51 ( ( -LRB- cord-015369-72cjogxz 7103 52 n n CC cord-015369-72cjogxz 7103 53 ¼ ¼ NNP cord-015369-72cjogxz 7103 54 4 4 CD cord-015369-72cjogxz 7103 55 ) ) -RRB- cord-015369-72cjogxz 7103 56 . . . cord-015369-72cjogxz 7104 1 Mean mean JJ cord-015369-72cjogxz 7104 2 time time NN cord-015369-72cjogxz 7104 3 to to TO cord-015369-72cjogxz 7104 4 re re VB cord-015369-72cjogxz 7104 5 - - NN cord-015369-72cjogxz 7104 6 transplantation transplantation NN cord-015369-72cjogxz 7104 7 was be VBD cord-015369-72cjogxz 7104 8 26 26 CD cord-015369-72cjogxz 7104 9 AE AE NNP cord-015369-72cjogxz 7104 10 27 27 CD cord-015369-72cjogxz 7104 11 days day NNS cord-015369-72cjogxz 7104 12 for for IN cord-015369-72cjogxz 7104 13 PGD PGD NNP cord-015369-72cjogxz 7104 14 , , , cord-015369-72cjogxz 7104 15 1,069 1,069 CD cord-015369-72cjogxz 7104 16 AE AE NNP cord-015369-72cjogxz 7104 17 57 57 CD cord-015369-72cjogxz 7104 18 days day NNS cord-015369-72cjogxz 7104 19 for for IN cord-015369-72cjogxz 7104 20 BOS BOS NNP cord-015369-72cjogxz 7104 21 and and CC cord-015369-72cjogxz 7104 22 220 220 CD cord-015369-72cjogxz 7104 23 AE AE NNP cord-015369-72cjogxz 7104 24 321 321 CD cord-015369-72cjogxz 7104 25 days day NNS cord-015369-72cjogxz 7104 26 for for IN cord-015369-72cjogxz 7104 27 AWP AWP NNP cord-015369-72cjogxz 7104 28 . . . cord-015369-72cjogxz 7105 1 Thirty thirty CD cord-015369-72cjogxz 7105 2 - - HYPH cord-015369-72cjogxz 7105 3 days day NNS cord-015369-72cjogxz 7105 4 , , , cord-015369-72cjogxz 7105 5 1-year 1-year CD cord-015369-72cjogxz 7105 6 and and CC cord-015369-72cjogxz 7105 7 5-years 5-years CD cord-015369-72cjogxz 7105 8 survival survival NN cord-015369-72cjogxz 7105 9 rates rate NNS cord-015369-72cjogxz 7105 10 after after IN cord-015369-72cjogxz 7105 11 PRT PRT NNP cord-015369-72cjogxz 7105 12 were be VBD cord-015369-72cjogxz 7105 13 52.2 52.2 CD cord-015369-72cjogxz 7105 14 , , , cord-015369-72cjogxz 7105 15 34.8 34.8 CD cord-015369-72cjogxz 7105 16 and and CC cord-015369-72cjogxz 7105 17 29.0 29.0 CD cord-015369-72cjogxz 7105 18 % % NN cord-015369-72cjogxz 7105 19 for for IN cord-015369-72cjogxz 7105 20 PGD PGD NNP cord-015369-72cjogxz 7105 21 ; ; : cord-015369-72cjogxz 7105 22 89.2 89.2 CD cord-015369-72cjogxz 7105 23 , , , cord-015369-72cjogxz 7105 24 72.5 72.5 CD cord-015369-72cjogxz 7105 25 and and CC cord-015369-72cjogxz 7105 26 61.3 61.3 CD cord-015369-72cjogxz 7105 27 % % NN cord-015369-72cjogxz 7105 28 for for IN cord-015369-72cjogxz 7105 29 BOS BOS NNP cord-015369-72cjogxz 7105 30 . . . cord-015369-72cjogxz 7106 1 All all DT cord-015369-72cjogxz 7106 2 4 4 CD cord-015369-72cjogxz 7106 3 patients patient NNS cord-015369-72cjogxz 7106 4 with with IN cord-015369-72cjogxz 7106 5 AWP AWP NNP cord-015369-72cjogxz 7106 6 are be VBP cord-015369-72cjogxz 7106 7 presently presently RB cord-015369-72cjogxz 7106 8 alive alive JJ cord-015369-72cjogxz 7107 1 ( ( -LRB- cord-015369-72cjogxz 7107 2 BOS BOS NNP cord-015369-72cjogxz 7107 3 vs. vs. IN cord-015369-72cjogxz 7107 4 PGD PGD NNP cord-015369-72cjogxz 7107 5 : : : cord-015369-72cjogxz 7108 1 p p NNP cord-015369-72cjogxz 7108 2 ¼ ¼ NNP cord-015369-72cjogxz 7108 3 0.02 0.02 CD cord-015369-72cjogxz 7108 4 ; ; : cord-015369-72cjogxz 7108 5 BOS BOS NNP cord-015369-72cjogxz 7108 6 vs. vs. IN cord-015369-72cjogxz 7108 7 AWP AWP NNP cord-015369-72cjogxz 7108 8 : : : cord-015369-72cjogxz 7109 1 p p NN cord-015369-72cjogxz 7109 2 ¼ ¼ CD cord-015369-72cjogxz 7109 3 0.27 0.27 CD cord-015369-72cjogxz 7110 1 ; ; : cord-015369-72cjogxz 7110 2 PGD PGD NNP cord-015369-72cjogxz 7110 3 vs. vs. IN cord-015369-72cjogxz 7110 4 AWP AWP NNP cord-015369-72cjogxz 7110 5 : : : cord-015369-72cjogxz 7111 1 p p NN cord-015369-72cjogxz 7111 2 ¼ ¼ NNP cord-015369-72cjogxz 7111 3 0.06 0.06 CD cord-015369-72cjogxz 7111 4 ) ) -RRB- cord-015369-72cjogxz 7111 5 . . . cord-015369-72cjogxz 7112 1 Long long JJ cord-015369-72cjogxz 7112 2 - - HYPH cord-015369-72cjogxz 7112 3 term term NN cord-015369-72cjogxz 7112 4 survival survival NN cord-015369-72cjogxz 7112 5 rates rate NNS cord-015369-72cjogxz 7112 6 for for IN cord-015369-72cjogxz 7112 7 PRT PRT NNP cord-015369-72cjogxz 7112 8 due due JJ cord-015369-72cjogxz 7112 9 to to IN cord-015369-72cjogxz 7112 10 PGD PGD NNP cord-015369-72cjogxz 7112 11 are be VBP cord-015369-72cjogxz 7112 12 significantly significantly RB cord-015369-72cjogxz 7112 13 lower low JJR cord-015369-72cjogxz 7112 14 , , , cord-015369-72cjogxz 7112 15 warranting warrant VBG cord-015369-72cjogxz 7112 16 restrictive restrictive JJ cord-015369-72cjogxz 7112 17 use use NN cord-015369-72cjogxz 7112 18 in in IN cord-015369-72cjogxz 7112 19 this this DT cord-015369-72cjogxz 7112 20 setting setting NN cord-015369-72cjogxz 7112 21 . . . cord-015369-72cjogxz 7113 1 In in IN cord-015369-72cjogxz 7113 2 our -PRON- PRP$ cord-015369-72cjogxz 7113 3 experience experience NN cord-015369-72cjogxz 7113 4 PRT PRT NNP cord-015369-72cjogxz 7113 5 for for IN cord-015369-72cjogxz 7113 6 AWP AWP NNP cord-015369-72cjogxz 7113 7 has have VBZ cord-015369-72cjogxz 7113 8 shown show VBN cord-015369-72cjogxz 7113 9 excellent excellent JJ cord-015369-72cjogxz 7113 10 results result NNS cord-015369-72cjogxz 7113 11 . . . cord-015369-72cjogxz 7114 1 PRT PRT NNP cord-015369-72cjogxz 7114 2 for for IN cord-015369-72cjogxz 7114 3 chronic chronic JJ cord-015369-72cjogxz 7114 4 problems problem NNS cord-015369-72cjogxz 7114 5 is be VBZ cord-015369-72cjogxz 7114 6 a a DT cord-015369-72cjogxz 7114 7 plausible plausible JJ cord-015369-72cjogxz 7114 8 approach approach NN cord-015369-72cjogxz 7114 9 , , , cord-015369-72cjogxz 7114 10 provided provide VBN cord-015369-72cjogxz 7114 11 that that IN cord-015369-72cjogxz 7114 12 patients patient NNS cord-015369-72cjogxz 7114 13 are be VBP cord-015369-72cjogxz 7114 14 carefully carefully RB cord-015369-72cjogxz 7114 15 selected select VBN cord-015369-72cjogxz 7114 16 . . . cord-015369-72cjogxz 7115 1 PRT PRT NNP cord-015369-72cjogxz 7115 2 for for IN cord-015369-72cjogxz 7115 3 PGD PGD NNP cord-015369-72cjogxz 7115 4 should should MD cord-015369-72cjogxz 7115 5 be be VB cord-015369-72cjogxz 7115 6 avoided avoid VBN cord-015369-72cjogxz 7115 7 . . . cord-015369-72cjogxz 7116 1 Herzchirurgie Herzchirurgie NNP cord-015369-72cjogxz 7116 2 /Chirurgie /Chirurgie . cord-015369-72cjogxz 7117 1 der der NNP cord-015369-72cjogxz 7117 2 thorakalen thorakalen NNP cord-015369-72cjogxz 7118 1 Aorta Aorta NNP cord-015369-72cjogxz 7118 2 Grundlagen Grundlagen NNP cord-015369-72cjogxz 7118 3 . . . cord-015369-72cjogxz 7119 1 Hämodynamisch Hämodynamisch NNP cord-015369-72cjogxz 7119 2 wirksame wirksame NNP cord-015369-72cjogxz 7120 1 Stenosen Stenosen NNP cord-015369-72cjogxz 7120 2 der der NNP cord-015369-72cjogxz 7120 3 Aorta Aorta NNP cord-015369-72cjogxz 7120 4 , , , cord-015369-72cjogxz 7120 5 insbesondere insbesondere NNP cord-015369-72cjogxz 7120 6 am be VBP cord-015369-72cjogxz 7120 7 thorakoabdominellen thorakoabdominellen NNP cord-015369-72cjogxz 7120 8 Ü Ü NNP cord-015369-72cjogxz 7120 9 bergang bergang NNP cord-015369-72cjogxz 7120 10 sind sind NNP cord-015369-72cjogxz 7120 11 eine eine NNP cord-015369-72cjogxz 7120 12 seltene seltene NNP cord-015369-72cjogxz 7120 13 Entität Entität NNP cord-015369-72cjogxz 7120 14 . . . cord-015369-72cjogxz 7121 1 Ü ü NN cord-015369-72cjogxz 7122 1 bliche bliche NNP cord-015369-72cjogxz 7122 2 Behandlungsstrategie Behandlungsstrategie NNP cord-015369-72cjogxz 7122 3 ist ist NN cord-015369-72cjogxz 7122 4 die die VBP cord-015369-72cjogxz 7122 5 konventionelle konventionelle NN cord-015369-72cjogxz 7122 6 , , , cord-015369-72cjogxz 7122 7 chirurgische chirurgische NNP cord-015369-72cjogxz 7122 8 Versorgung Versorgung NNP cord-015369-72cjogxz 7122 9 , , , cord-015369-72cjogxz 7122 10 neben neben NNP cord-015369-72cjogxz 7122 11 der der NNP cord-015369-72cjogxz 7122 12 weiteren weiteren NNP cord-015369-72cjogxz 7122 13 Option Option NNP cord-015369-72cjogxz 7122 14 einer einer NNP cord-015369-72cjogxz 7122 15 axillo axillo NNP cord-015369-72cjogxz 7122 16 - - HYPH cord-015369-72cjogxz 7122 17 bifemoralen bifemoralen NNP cord-015369-72cjogxz 7122 18 Bypassoperation Bypassoperation NNP cord-015369-72cjogxz 7122 19 . . . cord-015369-72cjogxz 7123 1 Die die VB cord-015369-72cjogxz 7124 1 endovaskuläre endovaskuläre NNP cord-015369-72cjogxz 7124 2 Stent Stent NNP cord-015369-72cjogxz 7124 3 - - HYPH cord-015369-72cjogxz 7124 4 Graft Graft NNP cord-015369-72cjogxz 7124 5 Insertion insertion NN cord-015369-72cjogxz 7124 6 dient dient NNP cord-015369-72cjogxz 7124 7 als als NN cord-015369-72cjogxz 7124 8 Behandlungmethode Behandlungmethode NNP cord-015369-72cjogxz 7124 9 erster erster NNP cord-015369-72cjogxz 7124 10 Wahl Wahl NNP cord-015369-72cjogxz 7124 11 für für IN cord-015369-72cjogxz 7124 12 zahlreiche zahlreiche NNP cord-015369-72cjogxz 7124 13 thorakale thorakale NNP cord-015369-72cjogxz 7124 14 und und NNP cord-015369-72cjogxz 7125 1 abdominelle abdominelle NNP cord-015369-72cjogxz 7125 2 Aortenpathologien Aortenpathologien NNP cord-015369-72cjogxz 7125 3 . . . cord-015369-72cjogxz 7126 1 Insbesondere Insbesondere NNP cord-015369-72cjogxz 7126 2 bei bei NNP cord-015369-72cjogxz 7126 3 älteren älteren NNP cord-015369-72cjogxz 7126 4 und und IN cord-015369-72cjogxz 7126 5 multimorbiden multimorbiden NNP cord-015369-72cjogxz 7127 1 Patienten Patienten NNP cord-015369-72cjogxz 7127 2 zeigt zeigt NNP cord-015369-72cjogxz 7127 3 sie sie NNP cord-015369-72cjogxz 7127 4 ihre ihre NNP cord-015369-72cjogxz 7127 5 Vorteile Vorteile NNP cord-015369-72cjogxz 7127 6 . . . cord-015369-72cjogxz 7128 1 Methodik Methodik NNP cord-015369-72cjogxz 7128 2 . . . cord-015369-72cjogxz 7129 1 Wir Wir NNP cord-015369-72cjogxz 7129 2 berichten berichten NNP cord-015369-72cjogxz 7129 3 von von NNP cord-015369-72cjogxz 7129 4 zwei zwei NNP cord-015369-72cjogxz 7129 5 Patienten Patienten NNP cord-015369-72cjogxz 7129 6 , , , cord-015369-72cjogxz 7129 7 die die VB cord-015369-72cjogxz 7129 8 aufgrund aufgrund NNP cord-015369-72cjogxz 7129 9 von von NNP cord-015369-72cjogxz 7129 10 Angina Angina NNP cord-015369-72cjogxz 7129 11 abdominalis abdominalis NNP cord-015369-72cjogxz 7129 12 , , , cord-015369-72cjogxz 7130 1 sowie sowie NNP cord-015369-72cjogxz 7130 2 Claudicatio Claudicatio NNP cord-015369-72cjogxz 7130 3 intermittens intermitten VBZ cord-015369-72cjogxz 7130 4 an an DT cord-015369-72cjogxz 7130 5 unser unser NNP cord-015369-72cjogxz 7130 6 Zentrum Zentrum NNP cord-015369-72cjogxz 7130 7 transferiert transferiert NN cord-015369-72cjogxz 7130 8 wurden wurden NNP cord-015369-72cjogxz 7130 9 . . . cord-015369-72cjogxz 7131 1 In in IN cord-015369-72cjogxz 7131 2 der der NN cord-015369-72cjogxz 7131 3 Computertomographie Computertomographie NNP cord-015369-72cjogxz 7131 4 zeigte zeigte NNP cord-015369-72cjogxz 7131 5 sich sich NNP cord-015369-72cjogxz 7131 6 jeweils jeweils NNP cord-015369-72cjogxz 7131 7 eine eine NNP cord-015369-72cjogxz 7131 8 symptomatische symptomatische NNP cord-015369-72cjogxz 7132 1 Stenose Stenose NNP cord-015369-72cjogxz 7132 2 der der NNP cord-015369-72cjogxz 7132 3 Aorta Aorta NNP cord-015369-72cjogxz 7132 4 am be VBP cord-015369-72cjogxz 7132 5 thorakoabdominellen thorakoabdominellen NNP cord-015369-72cjogxz 7132 6 Ü Ü NNP cord-015369-72cjogxz 7132 7 bergang bergang NNP cord-015369-72cjogxz 7132 8 ( ( -LRB- cord-015369-72cjogxz 7132 9 , , , cord-015369-72cjogxz 7132 10 , , , cord-015369-72cjogxz 7132 11 Coral Coral NNP cord-015369-72cjogxz 7132 12 - - HYPH cord-015369-72cjogxz 7132 13 reef reef NN cord-015369-72cjogxz 7132 14 aorta aorta NN cord-015369-72cjogxz 7132 15 ' ' '' cord-015369-72cjogxz 7132 16 ' ' '' cord-015369-72cjogxz 7132 17 ) ) -RRB- cord-015369-72cjogxz 7132 18 . . . cord-015369-72cjogxz 7133 1 Aufgrund Aufgrund NNP cord-015369-72cjogxz 7133 2 des des FW cord-015369-72cjogxz 7133 3 hohen hohen NNP cord-015369-72cjogxz 7133 4 Operationsrisikos Operationsrisikos NNP cord-015369-72cjogxz 7133 5 , , , cord-015369-72cjogxz 7133 6 das das NNP cord-015369-72cjogxz 7133 7 sich sich NNP cord-015369-72cjogxz 7133 8 insbesondere insbesondere NNP cord-015369-72cjogxz 7133 9 in in IN cord-015369-72cjogxz 7133 10 den den NNP cord-015369-72cjogxz 7133 11 EuroSCOREs EuroSCOREs NNP cord-015369-72cjogxz 7133 12 ( ( -LRB- cord-015369-72cjogxz 7133 13 numerisch numerisch NNP cord-015369-72cjogxz 7133 14 16 16 CD cord-015369-72cjogxz 7133 15 bzw bzw NNP cord-015369-72cjogxz 7133 16 . . . cord-015369-72cjogxz 7134 1 13 13 LS cord-015369-72cjogxz 7134 2 ) ) -RRB- cord-015369-72cjogxz 7134 3 zeigte zeigte NNP cord-015369-72cjogxz 7134 4 , , , cord-015369-72cjogxz 7134 5 wurden wurden NNP cord-015369-72cjogxz 7134 6 beide beide NNP cord-015369-72cjogxz 7134 7 Patienten Patienten NNP cord-015369-72cjogxz 7134 8 mittels mittels NNPS cord-015369-72cjogxz 7134 9 transfemoraler transfemoraler NN cord-015369-72cjogxz 7134 10 , , , cord-015369-72cjogxz 7134 11 endovaskulärer endovaskulärer NNP cord-015369-72cjogxz 7134 12 Stent Stent NNP cord-015369-72cjogxz 7134 13 - - HYPH cord-015369-72cjogxz 7134 14 Graft graft NN cord-015369-72cjogxz 7134 15 Insertion insertion NN cord-015369-72cjogxz 7134 16 versorgt versorgt NN cord-015369-72cjogxz 7134 17 . . . cord-015369-72cjogxz 7135 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 7135 2 . . . cord-015369-72cjogxz 7136 1 Beide Beide NNP cord-015369-72cjogxz 7136 2 Patienten Patienten NNP cord-015369-72cjogxz 7136 3 konnten konnten XX cord-015369-72cjogxz 7136 4 wenige wenige NN cord-015369-72cjogxz 7136 5 Tage Tage NNP cord-015369-72cjogxz 7136 6 nach nach NN cord-015369-72cjogxz 7136 7 dem dem NNP cord-015369-72cjogxz 7136 8 Eingriff Eingriff NNP cord-015369-72cjogxz 7136 9 entlassen entlassen NN cord-015369-72cjogxz 7137 1 werden werden NNP cord-015369-72cjogxz 7137 2 . . . cord-015369-72cjogxz 7138 1 Die die VB cord-015369-72cjogxz 7138 2 abschließenden abschließenden JJ cord-015369-72cjogxz 7138 3 Kontrollen Kontrollen NNP cord-015369-72cjogxz 7138 4 mittels mittels NNPS cord-015369-72cjogxz 7138 5 Computertomographie Computertomographie NNP cord-015369-72cjogxz 7139 1 zeigten zeigten NNP cord-015369-72cjogxz 7139 2 jeweils jeweils NNP cord-015369-72cjogxz 7139 3 den den NNP cord-015369-72cjogxz 7139 4 Stent Stent NNP cord-015369-72cjogxz 7139 5 - - HYPH cord-015369-72cjogxz 7139 6 Graft Graft NNP cord-015369-72cjogxz 7139 7 in in IN cord-015369-72cjogxz 7139 8 korrekter korrekt JJR cord-015369-72cjogxz 7139 9 Position position NN cord-015369-72cjogxz 7139 10 und und IN cord-015369-72cjogxz 7139 11 voller voller NNP cord-015369-72cjogxz 7139 12 Entfaltung Entfaltung NNP cord-015369-72cjogxz 7139 13 , , , cord-015369-72cjogxz 7139 14 sowie sowie NNP cord-015369-72cjogxz 7139 15 distal distal JJ cord-015369-72cjogxz 7139 16 davon davon NNP cord-015369-72cjogxz 7139 17 vollständig vollständig NNP cord-015369-72cjogxz 7139 18 wiederhergestellte wiederhergestellte NNP cord-015369-72cjogxz 7139 19 , , , cord-015369-72cjogxz 7139 20 antegrade antegrade NNP cord-015369-72cjogxz 7139 21 Perfusion Perfusion NNP cord-015369-72cjogxz 7139 22 . . . cord-015369-72cjogxz 7140 1 Die die VB cord-015369-72cjogxz 7141 1 Patienten Patienten NNP cord-015369-72cjogxz 7141 2 waren waren VBD cord-015369-72cjogxz 7141 3 zu zu NNP cord-015369-72cjogxz 7141 4 diesem diesem NNP cord-015369-72cjogxz 7141 5 Zeitpunkt Zeitpunkt NNP cord-015369-72cjogxz 7141 6 beschwerdefrei beschwerdefrei NNP cord-015369-72cjogxz 7142 1 und und NNP cord-015369-72cjogxz 7142 2 zeigten zeigten NNP cord-015369-72cjogxz 7142 3 auch auch NNP cord-015369-72cjogxz 7142 4 in in IN cord-015369-72cjogxz 7142 5 einer einer NNP cord-015369-72cjogxz 7142 6 CT CT NNP cord-015369-72cjogxz 7142 7 - - HYPH cord-015369-72cjogxz 7142 8 Kontrolle Kontrolle NNP cord-015369-72cjogxz 7142 9 nach nach NN cord-015369-72cjogxz 7142 10 6 6 CD cord-015369-72cjogxz 7142 11 Monaten Monaten NNP cord-015369-72cjogxz 7142 12 keine keine NNP cord-015369-72cjogxz 7142 13 Veränderung Veränderung NNP cord-015369-72cjogxz 7142 14 dieser dieser NNP cord-015369-72cjogxz 7142 15 Situation Situation NNP cord-015369-72cjogxz 7142 16 . . . cord-015369-72cjogxz 7143 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 7143 2 . . . cord-015369-72cjogxz 7144 1 Gleich Gleich NNP cord-015369-72cjogxz 7144 2 anderen anderen NNP cord-015369-72cjogxz 7144 3 Aortenpathologien Aortenpathologien NNP cord-015369-72cjogxz 7144 4 , , , cord-015369-72cjogxz 7144 5 wie wie NNP cord-015369-72cjogxz 7144 6 perforierende perforierende NNP cord-015369-72cjogxz 7144 7 Ulcera Ulcera NNP cord-015369-72cjogxz 7144 8 , , , cord-015369-72cjogxz 7144 9 ist ist NNP cord-015369-72cjogxz 7144 10 diese diese NNP cord-015369-72cjogxz 7144 11 sogenannte sogenannte NNP cord-015369-72cjogxz 7144 12 Korallenriffaorta Korallenriffaorta NNP cord-015369-72cjogxz 7144 13 das das NNP cord-015369-72cjogxz 7145 1 fortgeschrittene fortgeschrittene NNP cord-015369-72cjogxz 7145 2 Stadium Stadium NNP cord-015369-72cjogxz 7145 3 eines eines NNP cord-015369-72cjogxz 7145 4 obliterativen obliterativen NNP cord-015369-72cjogxz 7145 5 , , , cord-015369-72cjogxz 7145 6 atherosklerotischen atherosklerotischen NNP cord-015369-72cjogxz 7145 7 chronisch chronisch NNP cord-015369-72cjogxz 7145 8 - - HYPH cord-015369-72cjogxz 7145 9 systemischen systemischen NNP cord-015369-72cjogxz 7145 10 Prozesses Prozesses NNP cord-015369-72cjogxz 7145 11 . . . cord-015369-72cjogxz 7146 1 Gerade Gerade NNP cord-015369-72cjogxz 7146 2 deshalb deshalb NNP cord-015369-72cjogxz 7147 1 ist ist NNP cord-015369-72cjogxz 7147 2 der der NNP cord-015369-72cjogxz 7147 3 Allgemeinzustand Allgemeinzustand NNP cord-015369-72cjogxz 7147 4 dieser dieser NNP cord-015369-72cjogxz 7147 5 Patienten Patienten NNP cord-015369-72cjogxz 7147 6 meist meist NNP cord-015369-72cjogxz 7147 7 sehr sehr NNP cord-015369-72cjogxz 7147 8 schlecht schlecht NNP cord-015369-72cjogxz 7147 9 , , , cord-015369-72cjogxz 7147 10 weshalb weshalb NNP cord-015369-72cjogxz 7147 11 minimal minimal JJ cord-015369-72cjogxz 7147 12 invasive invasive JJ cord-015369-72cjogxz 7147 13 Therapieoptionen Therapieoptionen NNP cord-015369-72cjogxz 7147 14 vorteilhaft vorteilhaft NN cord-015369-72cjogxz 7147 15 erscheinen erscheinen NNP cord-015369-72cjogxz 7147 16 . . . cord-015369-72cjogxz 7148 1 Obgleich Obgleich NNP cord-015369-72cjogxz 7148 2 wenig wenig NNP cord-015369-72cjogxz 7148 3 Erfahrung Erfahrung NNP cord-015369-72cjogxz 7148 4 mit mit NNP cord-015369-72cjogxz 7148 5 der der NNP cord-015369-72cjogxz 7148 6 endovaskulären endovaskulären NNP cord-015369-72cjogxz 7148 7 Versorgung Versorgung NNP cord-015369-72cjogxz 7148 8 der der NNP cord-015369-72cjogxz 7148 9 Aortenstenose Aortenstenose NNP cord-015369-72cjogxz 7148 10 am be VBP cord-015369-72cjogxz 7148 11 thorakoabdominellen thorakoabdominellen NNP cord-015369-72cjogxz 7148 12 Ü Ü NNP cord-015369-72cjogxz 7148 13 bergang bergang NNP cord-015369-72cjogxz 7148 14 existiert existiert NNP cord-015369-72cjogxz 7148 15 , , , cord-015369-72cjogxz 7149 1 könnte könnte NNP cord-015369-72cjogxz 7149 2 diese diese NNP cord-015369-72cjogxz 7149 3 Option Option NNP cord-015369-72cjogxz 7149 4 zur zur NNP cord-015369-72cjogxz 7149 5 Behandlungsstrategie Behandlungsstrategie NNP cord-015369-72cjogxz 7149 6 erster erster NNP cord-015369-72cjogxz 7149 7 Wahl Wahl NNP cord-015369-72cjogxz 7149 8 werden werden NNP cord-015369-72cjogxz 7149 9 , , , cord-015369-72cjogxz 7149 10 indem indem NNP cord-015369-72cjogxz 7149 11 sie sie NNP cord-015369-72cjogxz 7149 12 minimale minimale NNP cord-015369-72cjogxz 7149 13 Invasivität Invasivität NNP cord-015369-72cjogxz 7149 14 mit mit NNP cord-015369-72cjogxz 7149 15 maximaler maximaler NN cord-015369-72cjogxz 7149 16 Effektivität Effektivität NNP cord-015369-72cjogxz 7149 17 vereint vereint NN cord-015369-72cjogxz 7149 18 . . . cord-015369-72cjogxz 7150 1 Paraplegia paraplegia NN cord-015369-72cjogxz 7150 2 after after IN cord-015369-72cjogxz 7150 3 thoracic thoracic JJ cord-015369-72cjogxz 7150 4 surgery surgery NN cord-015369-72cjogxz 7150 5 has have VBZ cord-015369-72cjogxz 7150 6 been be VBN cord-015369-72cjogxz 7150 7 reported report VBN cord-015369-72cjogxz 7150 8 in in IN cord-015369-72cjogxz 7150 9 the the DT cord-015369-72cjogxz 7150 10 literature literature NN cord-015369-72cjogxz 7150 11 . . . cord-015369-72cjogxz 7151 1 The the DT cord-015369-72cjogxz 7151 2 paraplegia paraplegia NN cord-015369-72cjogxz 7151 3 rate rate NN cord-015369-72cjogxz 7151 4 after after IN cord-015369-72cjogxz 7151 5 intrathoracic intrathoracic JJ cord-015369-72cjogxz 7151 6 operations operation NNS cord-015369-72cjogxz 7151 7 ranges range VBZ cord-015369-72cjogxz 7151 8 between between IN cord-015369-72cjogxz 7151 9 0.08 0.08 CD cord-015369-72cjogxz 7151 10 and and CC cord-015369-72cjogxz 7151 11 12 12 CD cord-015369-72cjogxz 7151 12 % % NN cord-015369-72cjogxz 7151 13 overall overall JJ cord-015369-72cjogxz 7151 14 . . . cord-015369-72cjogxz 7152 1 After after IN cord-015369-72cjogxz 7152 2 vascular vascular JJ cord-015369-72cjogxz 7152 3 surgery surgery NN cord-015369-72cjogxz 7152 4 for for IN cord-015369-72cjogxz 7152 5 ruptured ruptured JJ cord-015369-72cjogxz 7152 6 aneurysm aneurysm NN cord-015369-72cjogxz 7152 7 of of IN cord-015369-72cjogxz 7152 8 the the DT cord-015369-72cjogxz 7152 9 thoracic thoracic JJ cord-015369-72cjogxz 7152 10 aorta aorta NN cord-015369-72cjogxz 7152 11 paraplegia paraplegia NN cord-015369-72cjogxz 7152 12 has have VBZ cord-015369-72cjogxz 7152 13 been be VBN cord-015369-72cjogxz 7152 14 reported report VBN cord-015369-72cjogxz 7152 15 up up IN cord-015369-72cjogxz 7152 16 to to TO cord-015369-72cjogxz 7152 17 12 12 CD cord-015369-72cjogxz 7152 18 % % NN cord-015369-72cjogxz 7152 19 . . . cord-015369-72cjogxz 7153 1 However however RB cord-015369-72cjogxz 7153 2 ; ; : cord-015369-72cjogxz 7153 3 this this DT cord-015369-72cjogxz 7153 4 specific specific JJ cord-015369-72cjogxz 7153 5 complication complication NN cord-015369-72cjogxz 7153 6 is be VBZ cord-015369-72cjogxz 7153 7 greatly greatly RB cord-015369-72cjogxz 7153 8 reduced reduce VBN cord-015369-72cjogxz 7153 9 for for IN cord-015369-72cjogxz 7153 10 planned plan VBN cord-015369-72cjogxz 7153 11 surgery surgery NN cord-015369-72cjogxz 7153 12 ( ( -LRB- cord-015369-72cjogxz 7153 13 0.4 0.4 CD cord-015369-72cjogxz 7153 14 % % NN cord-015369-72cjogxz 7153 15 ) ) -RRB- cord-015369-72cjogxz 7153 16 . . . cord-015369-72cjogxz 7154 1 The the DT cord-015369-72cjogxz 7154 2 thoracoabdominal thoracoabdominal JJ cord-015369-72cjogxz 7154 3 approach approach NN cord-015369-72cjogxz 7154 4 for for IN cord-015369-72cjogxz 7154 5 oesophageal oesophageal JJ cord-015369-72cjogxz 7154 6 resection resection NN cord-015369-72cjogxz 7154 7 is be VBZ cord-015369-72cjogxz 7154 8 associated associate VBN cord-015369-72cjogxz 7154 9 with with IN cord-015369-72cjogxz 7154 10 a a DT cord-015369-72cjogxz 7154 11 risk risk NN cord-015369-72cjogxz 7154 12 of of IN cord-015369-72cjogxz 7154 13 0.2 0.2 CD cord-015369-72cjogxz 7154 14 % % NN cord-015369-72cjogxz 7154 15 . . . cord-015369-72cjogxz 7155 1 It -PRON- PRP cord-015369-72cjogxz 7155 2 is be VBZ cord-015369-72cjogxz 7155 3 unclear unclear JJ cord-015369-72cjogxz 7155 4 , , , cord-015369-72cjogxz 7155 5 whether whether IN cord-015369-72cjogxz 7155 6 thoracotomy thoracotomy NN cord-015369-72cjogxz 7155 7 alone alone RB cord-015369-72cjogxz 7155 8 , , , cord-015369-72cjogxz 7155 9 regardless regardless RB cord-015369-72cjogxz 7155 10 the the DT cord-015369-72cjogxz 7155 11 extent extent NN cord-015369-72cjogxz 7155 12 of of IN cord-015369-72cjogxz 7155 13 other other JJ cord-015369-72cjogxz 7155 14 surgical surgical JJ cord-015369-72cjogxz 7155 15 procedures procedure NNS cord-015369-72cjogxz 7155 16 bears bear VBZ cord-015369-72cjogxz 7155 17 a a DT cord-015369-72cjogxz 7155 18 risk risk NN cord-015369-72cjogxz 7155 19 for for IN cord-015369-72cjogxz 7155 20 paraplegia paraplegia NN cord-015369-72cjogxz 7155 21 . . . cord-015369-72cjogxz 7156 1 The the DT cord-015369-72cjogxz 7156 2 blood blood NN cord-015369-72cjogxz 7156 3 supply supply NN cord-015369-72cjogxz 7156 4 of of IN cord-015369-72cjogxz 7156 5 the the DT cord-015369-72cjogxz 7156 6 spinal spinal JJ cord-015369-72cjogxz 7156 7 cord cord NN cord-015369-72cjogxz 7156 8 in in IN cord-015369-72cjogxz 7156 9 adult adult NN cord-015369-72cjogxz 7156 10 is be VBZ cord-015369-72cjogxz 7156 11 highly highly RB cord-015369-72cjogxz 7156 12 variable variable JJ cord-015369-72cjogxz 7156 13 . . . cord-015369-72cjogxz 7157 1 We -PRON- PRP cord-015369-72cjogxz 7157 2 report report VBP cord-015369-72cjogxz 7157 3 on on IN cord-015369-72cjogxz 7157 4 a a DT cord-015369-72cjogxz 7157 5 case case NN cord-015369-72cjogxz 7157 6 of of IN cord-015369-72cjogxz 7157 7 paraplegia paraplegia NN cord-015369-72cjogxz 7157 8 after after IN cord-015369-72cjogxz 7157 9 an an DT cord-015369-72cjogxz 7157 10 uneventful uneventful JJ cord-015369-72cjogxz 7157 11 thoracotomy thoracotomy NN cord-015369-72cjogxz 7157 12 in in IN cord-015369-72cjogxz 7157 13 a a DT cord-015369-72cjogxz 7157 14 47 47 CD cord-015369-72cjogxz 7157 15 year year NN cord-015369-72cjogxz 7157 16 - - HYPH cord-015369-72cjogxz 7157 17 old old JJ cord-015369-72cjogxz 7157 18 man man NN cord-015369-72cjogxz 7157 19 . . . cord-015369-72cjogxz 7158 1 Indication indication NN cord-015369-72cjogxz 7158 2 for for IN cord-015369-72cjogxz 7158 3 surgery surgery NN cord-015369-72cjogxz 7158 4 was be VBD cord-015369-72cjogxz 7158 5 an an DT cord-015369-72cjogxz 7158 6 epiphrenic epiphrenic JJ cord-015369-72cjogxz 7158 7 diverticulum diverticulum NN cord-015369-72cjogxz 7158 8 of of IN cord-015369-72cjogxz 7158 9 the the DT cord-015369-72cjogxz 7158 10 oesophagus oesophagus NN cord-015369-72cjogxz 7158 11 . . . cord-015369-72cjogxz 7159 1 Paraplegia paraplegia NN cord-015369-72cjogxz 7159 2 after after IN cord-015369-72cjogxz 7159 3 thoracotomy thoracotomy NN cord-015369-72cjogxz 7159 4 is be VBZ cord-015369-72cjogxz 7159 5 a a DT cord-015369-72cjogxz 7159 6 rare rare JJ cord-015369-72cjogxz 7159 7 but but CC cord-015369-72cjogxz 7159 8 typical typical JJ cord-015369-72cjogxz 7159 9 complication complication NN cord-015369-72cjogxz 7159 10 and and CC cord-015369-72cjogxz 7159 11 should should MD cord-015369-72cjogxz 7159 12 be be VB cord-015369-72cjogxz 7159 13 mandatory mandatory JJ cord-015369-72cjogxz 7159 14 included include VBN cord-015369-72cjogxz 7159 15 in in IN cord-015369-72cjogxz 7159 16 informed informed JJ cord-015369-72cjogxz 7159 17 consent consent NN cord-015369-72cjogxz 7159 18 . . . cord-015369-72cjogxz 7160 1 Background background NN cord-015369-72cjogxz 7160 2 . . . cord-015369-72cjogxz 7161 1 Total total JJ cord-015369-72cjogxz 7161 2 supra supra JJ cord-015369-72cjogxz 7161 3 - - HYPH cord-015369-72cjogxz 7161 4 aortic aortic JJ cord-015369-72cjogxz 7161 5 rerouting rerouting NN cord-015369-72cjogxz 7161 6 as as RB cord-015369-72cjogxz 7161 7 well well RB cord-015369-72cjogxz 7161 8 as as IN cord-015369-72cjogxz 7161 9 double double JJ cord-015369-72cjogxz 7161 10 vessel vessel NN cord-015369-72cjogxz 7161 11 transposition transposition NN cord-015369-72cjogxz 7161 12 followed follow VBN cord-015369-72cjogxz 7161 13 by by IN cord-015369-72cjogxz 7161 14 endovascular endovascular JJ cord-015369-72cjogxz 7161 15 stent stent NN cord-015369-72cjogxz 7161 16 graft graft NN cord-015369-72cjogxz 7161 17 placement placement NN cord-015369-72cjogxz 7161 18 are be VBP cord-015369-72cjogxz 7161 19 now now RB cord-015369-72cjogxz 7161 20 an an DT cord-015369-72cjogxz 7161 21 established establish VBN cord-015369-72cjogxz 7161 22 tool tool NN cord-015369-72cjogxz 7161 23 for for IN cord-015369-72cjogxz 7161 24 the the DT cord-015369-72cjogxz 7161 25 treatment treatment NN cord-015369-72cjogxz 7161 26 of of IN cord-015369-72cjogxz 7161 27 various various JJ cord-015369-72cjogxz 7161 28 aortic aortic JJ cord-015369-72cjogxz 7161 29 arch arch JJ cord-015369-72cjogxz 7161 30 pathologies pathology NNS cord-015369-72cjogxz 7161 31 . . . cord-015369-72cjogxz 7162 1 However however RB cord-015369-72cjogxz 7162 2 , , , cord-015369-72cjogxz 7162 3 details detail NNS cord-015369-72cjogxz 7162 4 about about IN cord-015369-72cjogxz 7162 5 the the DT cord-015369-72cjogxz 7162 6 motion motion NN cord-015369-72cjogxz 7162 7 of of IN cord-015369-72cjogxz 7162 8 the the DT cord-015369-72cjogxz 7162 9 aortic aortic JJ cord-015369-72cjogxz 7162 10 arch arch NN cord-015369-72cjogxz 7162 11 after after IN cord-015369-72cjogxz 7162 12 this this DT cord-015369-72cjogxz 7162 13 procedure procedure NN cord-015369-72cjogxz 7162 14 remain remain VBP cord-015369-72cjogxz 7162 15 unknown unknown JJ cord-015369-72cjogxz 7162 16 . . . cord-015369-72cjogxz 7163 1 Moreover moreover RB cord-015369-72cjogxz 7163 2 , , , cord-015369-72cjogxz 7163 3 no no DT cord-015369-72cjogxz 7163 4 perfectly perfectly RB cord-015369-72cjogxz 7163 5 fitting fitting JJ cord-015369-72cjogxz 7163 6 risk risk NN cord-015369-72cjogxz 7163 7 stratification stratification NN cord-015369-72cjogxz 7163 8 score score NN cord-015369-72cjogxz 7163 9 exists exist VBZ cord-015369-72cjogxz 7163 10 for for IN cord-015369-72cjogxz 7163 11 outcome outcome NN cord-015369-72cjogxz 7163 12 prediction prediction NN cord-015369-72cjogxz 7163 13 of of IN cord-015369-72cjogxz 7163 14 this this DT cord-015369-72cjogxz 7163 15 specific specific JJ cord-015369-72cjogxz 7163 16 patients patient NNS cord-015369-72cjogxz 7163 17 . . . cord-015369-72cjogxz 7164 1 Methods method NNS cord-015369-72cjogxz 7164 2 . . . cord-015369-72cjogxz 7165 1 We -PRON- PRP cord-015369-72cjogxz 7165 2 applied apply VBD cord-015369-72cjogxz 7165 3 a a DT cord-015369-72cjogxz 7165 4 fully fully RB cord-015369-72cjogxz 7165 5 automated automate VBN cord-015369-72cjogxz 7165 6 method method NN cord-015369-72cjogxz 7165 7 to to TO cord-015369-72cjogxz 7165 8 quantify quantify VB cord-015369-72cjogxz 7165 9 the the DT cord-015369-72cjogxz 7165 10 deformation deformation NN cord-015369-72cjogxz 7165 11 patterns pattern NNS cord-015369-72cjogxz 7165 12 of of IN cord-015369-72cjogxz 7165 13 the the DT cord-015369-72cjogxz 7165 14 aortic aortic JJ cord-015369-72cjogxz 7165 15 arch arch NN cord-015369-72cjogxz 7165 16 in in IN cord-015369-72cjogxz 7165 17 a a DT cord-015369-72cjogxz 7165 18 gated gated JJ cord-015369-72cjogxz 7165 19 CT CT NNP cord-015369-72cjogxz 7165 20 sequence sequence NN cord-015369-72cjogxz 7165 21 . . . cord-015369-72cjogxz 7166 1 The the DT cord-015369-72cjogxz 7166 2 aorta aorta NN cord-015369-72cjogxz 7166 3 is be VBZ cord-015369-72cjogxz 7166 4 detected detect VBN cord-015369-72cjogxz 7166 5 and and CC cord-015369-72cjogxz 7166 6 segmented segment VBN cord-015369-72cjogxz 7166 7 by by IN cord-015369-72cjogxz 7166 8 an an DT cord-015369-72cjogxz 7166 9 active active JJ cord-015369-72cjogxz 7166 10 surface surface NN cord-015369-72cjogxz 7166 11 approach approach NN cord-015369-72cjogxz 7166 12 , , , cord-015369-72cjogxz 7166 13 that that WDT cord-015369-72cjogxz 7166 14 accurately accurately RB cord-015369-72cjogxz 7166 15 identifies identify VBZ cord-015369-72cjogxz 7166 16 the the DT cord-015369-72cjogxz 7166 17 vessel vessel NN cord-015369-72cjogxz 7166 18 wall wall NN cord-015369-72cjogxz 7166 19 in in IN cord-015369-72cjogxz 7166 20 all all DT cord-015369-72cjogxz 7166 21 frames frame NNS cord-015369-72cjogxz 7166 22 . . . cord-015369-72cjogxz 7167 1 The the DT cord-015369-72cjogxz 7167 2 correspondences correspondence NNS cord-015369-72cjogxz 7167 3 of of IN cord-015369-72cjogxz 7167 4 landmarks landmark NNS cord-015369-72cjogxz 7167 5 on on IN cord-015369-72cjogxz 7167 6 the the DT cord-015369-72cjogxz 7167 7 vessel vessel NN cord-015369-72cjogxz 7167 8 wall wall NN cord-015369-72cjogxz 7167 9 are be VBP cord-015369-72cjogxz 7167 10 established establish VBN cord-015369-72cjogxz 7167 11 by by IN cord-015369-72cjogxz 7167 12 tracking track VBG cord-015369-72cjogxz 7167 13 the the DT cord-015369-72cjogxz 7167 14 deformation deformation NN cord-015369-72cjogxz 7167 15 during during IN cord-015369-72cjogxz 7167 16 the the DT cord-015369-72cjogxz 7167 17 cardiac cardiac JJ cord-015369-72cjogxz 7167 18 cycle cycle NN cord-015369-72cjogxz 7167 19 , , , cord-015369-72cjogxz 7167 20 resulting result VBG cord-015369-72cjogxz 7167 21 in in IN cord-015369-72cjogxz 7167 22 a a DT cord-015369-72cjogxz 7167 23 dynamic dynamic JJ cord-015369-72cjogxz 7167 24 deformation deformation NN cord-015369-72cjogxz 7167 25 model model NN cord-015369-72cjogxz 7167 26 of of IN cord-015369-72cjogxz 7167 27 the the DT cord-015369-72cjogxz 7167 28 structure structure NN cord-015369-72cjogxz 7167 29 . . . cord-015369-72cjogxz 7168 1 Results result NNS cord-015369-72cjogxz 7168 2 . . . cord-015369-72cjogxz 7169 1 With with IN cord-015369-72cjogxz 7169 2 help help NN cord-015369-72cjogxz 7169 3 of of IN cord-015369-72cjogxz 7169 4 this this DT cord-015369-72cjogxz 7169 5 model model NN cord-015369-72cjogxz 7169 6 , , , cord-015369-72cjogxz 7169 7 global global JJ cord-015369-72cjogxz 7169 8 and and CC cord-015369-72cjogxz 7169 9 local local JJ cord-015369-72cjogxz 7169 10 deformation deformation NN cord-015369-72cjogxz 7169 11 properties property NNS cord-015369-72cjogxz 7169 12 like like IN cord-015369-72cjogxz 7169 13 stretching stretch VBG cord-015369-72cjogxz 7169 14 and and CC cord-015369-72cjogxz 7169 15 bending bend VBG cord-015369-72cjogxz 7169 16 were be VBD cord-015369-72cjogxz 7169 17 measured measure VBN cord-015369-72cjogxz 7169 18 . . . cord-015369-72cjogxz 7170 1 After after IN cord-015369-72cjogxz 7170 2 registering register VBG cord-015369-72cjogxz 7170 3 the the DT cord-015369-72cjogxz 7170 4 models model NNS cord-015369-72cjogxz 7170 5 acquired acquire VBD cord-015369-72cjogxz 7170 6 pre pre JJ cord-015369-72cjogxz 7170 7 - - NN cord-015369-72cjogxz 7170 8 treatment treatment JJ cord-015369-72cjogxz 7170 9 , , , cord-015369-72cjogxz 7170 10 post post NN cord-015369-72cjogxz 7170 11 - - NN cord-015369-72cjogxz 7170 12 transposition transposition NN cord-015369-72cjogxz 7170 13 , , , cord-015369-72cjogxz 7170 14 and and CC cord-015369-72cjogxz 7170 15 post post JJ cord-015369-72cjogxz 7170 16 - - JJ cord-015369-72cjogxz 7170 17 stent stent JJ cord-015369-72cjogxz 7170 18 - - HYPH cord-015369-72cjogxz 7170 19 graft graft NN cord-015369-72cjogxz 7170 20 - - HYPH cord-015369-72cjogxz 7170 21 placement placement NN cord-015369-72cjogxz 7170 22 we -PRON- PRP cord-015369-72cjogxz 7170 23 compared compare VBD cord-015369-72cjogxz 7170 24 these these DT cord-015369-72cjogxz 7170 25 local local JJ cord-015369-72cjogxz 7170 26 properties property NNS cord-015369-72cjogxz 7170 27 and and CC cord-015369-72cjogxz 7170 28 were be VBD cord-015369-72cjogxz 7170 29 able able JJ cord-015369-72cjogxz 7170 30 to to TO cord-015369-72cjogxz 7170 31 quantify quantify VB cord-015369-72cjogxz 7170 32 the the DT cord-015369-72cjogxz 7170 33 change change NN cord-015369-72cjogxz 7170 34 caused cause VBN cord-015369-72cjogxz 7170 35 to to IN cord-015369-72cjogxz 7170 36 the the DT cord-015369-72cjogxz 7170 37 aortic aortic JJ cord-015369-72cjogxz 7170 38 arch arch NN cord-015369-72cjogxz 7170 39 motion motion NN cord-015369-72cjogxz 7170 40 . . . cord-015369-72cjogxz 7171 1 Conclusions conclusion NNS cord-015369-72cjogxz 7171 2 . . . cord-015369-72cjogxz 7172 1 This this DT cord-015369-72cjogxz 7172 2 new new JJ cord-015369-72cjogxz 7172 3 method method NN cord-015369-72cjogxz 7172 4 of of IN cord-015369-72cjogxz 7172 5 automated automate VBN cord-015369-72cjogxz 7172 6 computational computational JJ cord-015369-72cjogxz 7172 7 motion motion NN cord-015369-72cjogxz 7172 8 analysis analysis NN cord-015369-72cjogxz 7172 9 of of IN cord-015369-72cjogxz 7172 10 the the DT cord-015369-72cjogxz 7172 11 aortic aortic JJ cord-015369-72cjogxz 7172 12 arch arch NN cord-015369-72cjogxz 7172 13 may may MD cord-015369-72cjogxz 7172 14 establish establish VB cord-015369-72cjogxz 7172 15 a a DT cord-015369-72cjogxz 7172 16 risk risk NN cord-015369-72cjogxz 7172 17 stratification stratification NN cord-015369-72cjogxz 7172 18 score score NN cord-015369-72cjogxz 7172 19 for for IN cord-015369-72cjogxz 7172 20 outcome outcome NN cord-015369-72cjogxz 7172 21 prediction prediction NN cord-015369-72cjogxz 7172 22 after after IN cord-015369-72cjogxz 7172 23 supra supra JJ cord-015369-72cjogxz 7172 24 - - HYPH cord-015369-72cjogxz 7172 25 aortic aortic JJ cord-015369-72cjogxz 7172 26 rerouting rerouting NN cord-015369-72cjogxz 7172 27 followed follow VBN cord-015369-72cjogxz 7172 28 by by IN cord-015369-72cjogxz 7172 29 endovascular endovascular JJ cord-015369-72cjogxz 7172 30 stent stent JJ cord-015369-72cjogxz 7172 31 - - HYPH cord-015369-72cjogxz 7172 32 graft graft NN cord-015369-72cjogxz 7172 33 placement placement NN cord-015369-72cjogxz 7172 34 . . . cord-015369-72cjogxz 7173 1 Background background NN cord-015369-72cjogxz 7173 2 . . . cord-015369-72cjogxz 7174 1 Simultaneous simultaneous JJ cord-015369-72cjogxz 7174 2 surgical surgical JJ cord-015369-72cjogxz 7174 3 repair repair NN cord-015369-72cjogxz 7174 4 and and CC cord-015369-72cjogxz 7174 5 endovascular endovascular JJ cord-015369-72cjogxz 7174 6 treatment treatment NN cord-015369-72cjogxz 7174 7 are be VBP cord-015369-72cjogxz 7174 8 now now RB cord-015369-72cjogxz 7174 9 a a DT cord-015369-72cjogxz 7174 10 common common JJ cord-015369-72cjogxz 7174 11 approach approach NN cord-015369-72cjogxz 7174 12 for for IN cord-015369-72cjogxz 7174 13 various various JJ cord-015369-72cjogxz 7174 14 aortic aortic JJ cord-015369-72cjogxz 7174 15 pathologies pathology NNS cord-015369-72cjogxz 7174 16 . . . cord-015369-72cjogxz 7175 1 For for IN cord-015369-72cjogxz 7175 2 minimizing minimize VBG cord-015369-72cjogxz 7175 3 the the DT cord-015369-72cjogxz 7175 4 risk risk NN cord-015369-72cjogxz 7175 5 of of IN cord-015369-72cjogxz 7175 6 an an DT cord-015369-72cjogxz 7175 7 untreated untreated JJ cord-015369-72cjogxz 7175 8 descending descend VBG cord-015369-72cjogxz 7175 9 aorta aorta NN cord-015369-72cjogxz 7175 10 after after IN cord-015369-72cjogxz 7175 11 surgical surgical JJ cord-015369-72cjogxz 7175 12 repair repair NN cord-015369-72cjogxz 7175 13 of of IN cord-015369-72cjogxz 7175 14 ascending ascend VBG cord-015369-72cjogxz 7175 15 aorta aorta NN cord-015369-72cjogxz 7175 16 in in IN cord-015369-72cjogxz 7175 17 acute acute JJ cord-015369-72cjogxz 7175 18 Stanford Stanford NNP cord-015369-72cjogxz 7175 19 type type NN cord-015369-72cjogxz 7175 20 A a DT cord-015369-72cjogxz 7175 21 dissections dissection NNS cord-015369-72cjogxz 7175 22 a a DT cord-015369-72cjogxz 7175 23 new new JJ cord-015369-72cjogxz 7175 24 type type NN cord-015369-72cjogxz 7175 25 of of IN cord-015369-72cjogxz 7175 26 bare bare JJ cord-015369-72cjogxz 7175 27 - - HYPH cord-015369-72cjogxz 7175 28 metal metal NN cord-015369-72cjogxz 7175 29 stents stent NNS cord-015369-72cjogxz 7175 30 was be VBD cord-015369-72cjogxz 7175 31 established establish VBN cord-015369-72cjogxz 7175 32 . . . cord-015369-72cjogxz 7176 1 Methods method NNS cord-015369-72cjogxz 7176 2 . . . cord-015369-72cjogxz 7177 1 From from IN cord-015369-72cjogxz 7177 2 August August NNP cord-015369-72cjogxz 7177 3 2006 2006 CD cord-015369-72cjogxz 7177 4 to to IN cord-015369-72cjogxz 7177 5 January January NNP cord-015369-72cjogxz 7177 6 2007 2007 CD cord-015369-72cjogxz 7177 7 we -PRON- PRP cord-015369-72cjogxz 7177 8 performed perform VBD cord-015369-72cjogxz 7177 9 combined combined JJ cord-015369-72cjogxz 7177 10 surgical surgical JJ cord-015369-72cjogxz 7177 11 and and CC cord-015369-72cjogxz 7177 12 endovascular endovascular JJ cord-015369-72cjogxz 7177 13 treatment treatment NN cord-015369-72cjogxz 7177 14 with with IN cord-015369-72cjogxz 7177 15 the the DT cord-015369-72cjogxz 7177 16 Djumbodis Djumbodis NNP cord-015369-72cjogxz 7177 17 Dissection Dissection NNP cord-015369-72cjogxz 7177 18 System System NNP cord-015369-72cjogxz 7177 19 in in IN cord-015369-72cjogxz 7177 20 8 8 CD cord-015369-72cjogxz 7177 21 patients patient NNS cord-015369-72cjogxz 7177 22 ( ( -LRB- cord-015369-72cjogxz 7177 23 mean mean VB cord-015369-72cjogxz 7177 24 age age NN cord-015369-72cjogxz 7177 25 59 59 CD cord-015369-72cjogxz 7177 26 ) ) -RRB- cord-015369-72cjogxz 7177 27 suffering suffer VBG cord-015369-72cjogxz 7177 28 from from IN cord-015369-72cjogxz 7177 29 acute acute JJ cord-015369-72cjogxz 7177 30 type type NN cord-015369-72cjogxz 7177 31 A a NN cord-015369-72cjogxz 7177 32 dissections dissection NNS cord-015369-72cjogxz 7177 33 . . . cord-015369-72cjogxz 7178 1 Results result NNS cord-015369-72cjogxz 7178 2 . . . cord-015369-72cjogxz 7179 1 Early early JJ cord-015369-72cjogxz 7179 2 results result NNS cord-015369-72cjogxz 7179 3 after after IN cord-015369-72cjogxz 7179 4 treatment treatment NN cord-015369-72cjogxz 7179 5 obtained obtain VBN cord-015369-72cjogxz 7179 6 by by IN cord-015369-72cjogxz 7179 7 gated gate VBN cord-015369-72cjogxz 7179 8 CT CT NNP cord-015369-72cjogxz 7179 9 scans scan NNS cord-015369-72cjogxz 7179 10 were be VBD cord-015369-72cjogxz 7179 11 satisfactory satisfactory JJ cord-015369-72cjogxz 7179 12 . . . cord-015369-72cjogxz 7180 1 Nevertheless nevertheless RB cord-015369-72cjogxz 7180 2 , , , cord-015369-72cjogxz 7180 3 thrombosis thrombosis NN cord-015369-72cjogxz 7180 4 of of IN cord-015369-72cjogxz 7180 5 the the DT cord-015369-72cjogxz 7180 6 false false JJ cord-015369-72cjogxz 7180 7 lumen lumen NN cord-015369-72cjogxz 7180 8 was be VBD cord-015369-72cjogxz 7180 9 not not RB cord-015369-72cjogxz 7180 10 enhanced enhance VBN cord-015369-72cjogxz 7180 11 in in IN cord-015369-72cjogxz 7180 12 most most JJS cord-015369-72cjogxz 7180 13 patients patient NNS cord-015369-72cjogxz 7180 14 . . . cord-015369-72cjogxz 7181 1 Combined combined JJ cord-015369-72cjogxz 7181 2 surgical surgical JJ cord-015369-72cjogxz 7181 3 and and CC cord-015369-72cjogxz 7181 4 endovascular endovascular JJ cord-015369-72cjogxz 7181 5 approaches approach NNS cord-015369-72cjogxz 7181 6 need need VBP cord-015369-72cjogxz 7181 7 stent stent NN cord-015369-72cjogxz 7181 8 devices device NNS cord-015369-72cjogxz 7181 9 with with IN cord-015369-72cjogxz 7181 10 a a DT cord-015369-72cjogxz 7181 11 self self NN cord-015369-72cjogxz 7181 12 expanding expand VBG cord-015369-72cjogxz 7181 13 capability capability NN cord-015369-72cjogxz 7181 14 , , , cord-015369-72cjogxz 7181 15 since since IN cord-015369-72cjogxz 7181 16 the the DT cord-015369-72cjogxz 7181 17 Djumbodis Djumbodis NNP cord-015369-72cjogxz 7181 18 stent stent NN cord-015369-72cjogxz 7181 19 seems seem VBZ cord-015369-72cjogxz 7181 20 to to TO cord-015369-72cjogxz 7181 21 be be VB cord-015369-72cjogxz 7181 22 not not RB cord-015369-72cjogxz 7181 23 that that DT cord-015369-72cjogxz 7181 24 attached attach VBN cord-015369-72cjogxz 7181 25 to to IN cord-015369-72cjogxz 7181 26 the the DT cord-015369-72cjogxz 7181 27 aortic aortic JJ cord-015369-72cjogxz 7181 28 wall wall NN cord-015369-72cjogxz 7181 29 during during IN cord-015369-72cjogxz 7181 30 systolic systolic JJ cord-015369-72cjogxz 7181 31 excursion excursion NN cord-015369-72cjogxz 7181 32 . . . cord-015369-72cjogxz 7182 1 Conclusions conclusion NNS cord-015369-72cjogxz 7182 2 . . . cord-015369-72cjogxz 7183 1 Additional additional JJ cord-015369-72cjogxz 7183 2 implantation implantation NN cord-015369-72cjogxz 7183 3 of of IN cord-015369-72cjogxz 7183 4 the the DT cord-015369-72cjogxz 7183 5 non non JJ cord-015369-72cjogxz 7183 6 - - JJ cord-015369-72cjogxz 7183 7 covered covered JJ cord-015369-72cjogxz 7183 8 , , , cord-015369-72cjogxz 7183 9 non non JJ cord-015369-72cjogxz 7183 10 - - JJ cord-015369-72cjogxz 7183 11 self self NN cord-015369-72cjogxz 7183 12 - - HYPH cord-015369-72cjogxz 7183 13 expanding expand VBG cord-015369-72cjogxz 7183 14 Djumbodis Djumbodis NNP cord-015369-72cjogxz 7183 15 device device NN cord-015369-72cjogxz 7183 16 in in IN cord-015369-72cjogxz 7183 17 the the DT cord-015369-72cjogxz 7183 18 distal distal JJ cord-015369-72cjogxz 7183 19 arch arch NN cord-015369-72cjogxz 7183 20 and and CC cord-015369-72cjogxz 7183 21 the the DT cord-015369-72cjogxz 7183 22 proximal proximal JJ cord-015369-72cjogxz 7183 23 descending descend VBG cord-015369-72cjogxz 7183 24 aorta aorta NN cord-015369-72cjogxz 7183 25 does do VBZ cord-015369-72cjogxz 7183 26 in in IN cord-015369-72cjogxz 7183 27 most most JJS cord-015369-72cjogxz 7183 28 cases case NNS cord-015369-72cjogxz 7183 29 not not RB cord-015369-72cjogxz 7183 30 enhance enhance VB cord-015369-72cjogxz 7183 31 thrombosis thrombosis NN cord-015369-72cjogxz 7183 32 of of IN cord-015369-72cjogxz 7183 33 the the DT cord-015369-72cjogxz 7183 34 false false JJ cord-015369-72cjogxz 7183 35 lumen lumen NN cord-015369-72cjogxz 7183 36 in in IN cord-015369-72cjogxz 7183 37 patients patient NNS cord-015369-72cjogxz 7183 38 undergoing undergo VBG cord-015369-72cjogxz 7183 39 surgery surgery NN cord-015369-72cjogxz 7183 40 for for IN cord-015369-72cjogxz 7183 41 acute acute JJ cord-015369-72cjogxz 7183 42 Type type NN cord-015369-72cjogxz 7183 43 A A NNP cord-015369-72cjogxz 7183 44 dissections dissection NNS cord-015369-72cjogxz 7183 45 . . . cord-015369-72cjogxz 7184 1 The the DT cord-015369-72cjogxz 7184 2 most most RBS cord-015369-72cjogxz 7184 3 limiting limiting JJ cord-015369-72cjogxz 7184 4 factor factor NN cord-015369-72cjogxz 7184 5 seems seem VBZ cord-015369-72cjogxz 7184 6 to to TO cord-015369-72cjogxz 7184 7 be be VB cord-015369-72cjogxz 7184 8 the the DT cord-015369-72cjogxz 7184 9 non non AFX cord-015369-72cjogxz 7184 10 self self NN cord-015369-72cjogxz 7184 11 - - HYPH cord-015369-72cjogxz 7184 12 expanding expand VBG cord-015369-72cjogxz 7184 13 capability capability NN cord-015369-72cjogxz 7184 14 of of IN cord-015369-72cjogxz 7184 15 the the DT cord-015369-72cjogxz 7184 16 device device NN cord-015369-72cjogxz 7184 17 . . . cord-015369-72cjogxz 7185 1 The the DT cord-015369-72cjogxz 7185 2 purpose purpose NN cord-015369-72cjogxz 7185 3 of of IN cord-015369-72cjogxz 7185 4 this this DT cord-015369-72cjogxz 7185 5 study study NN cord-015369-72cjogxz 7185 6 was be VBD cord-015369-72cjogxz 7185 7 to to TO cord-015369-72cjogxz 7185 8 evaluate evaluate VB cord-015369-72cjogxz 7185 9 outcome outcome NN cord-015369-72cjogxz 7185 10 in in IN cord-015369-72cjogxz 7185 11 patients patient NNS cord-015369-72cjogxz 7185 12 with with IN cord-015369-72cjogxz 7185 13 a a DT cord-015369-72cjogxz 7185 14 small small JJ cord-015369-72cjogxz 7185 15 aortic aortic JJ cord-015369-72cjogxz 7185 16 root root NN cord-015369-72cjogxz 7185 17 receiving receive VBG cord-015369-72cjogxz 7185 18 either either CC cord-015369-72cjogxz 7185 19 a a DT cord-015369-72cjogxz 7185 20 standard standard JJ cord-015369-72cjogxz 7185 21 CarboMedics CarboMedics NNP cord-015369-72cjogxz 7185 22 or or CC cord-015369-72cjogxz 7185 23 a a DT cord-015369-72cjogxz 7185 24 Top Top NNP cord-015369-72cjogxz 7185 25 Hat Hat NNP cord-015369-72cjogxz 7185 26 mechanical mechanical JJ cord-015369-72cjogxz 7185 27 aortic aortic JJ cord-015369-72cjogxz 7185 28 valve valve NN cord-015369-72cjogxz 7185 29 . . . cord-015369-72cjogxz 7186 1 Cox Cox NNP cord-015369-72cjogxz 7186 2 regression regression NN cord-015369-72cjogxz 7186 3 analysis analysis NN cord-015369-72cjogxz 7186 4 revealed reveal VBD cord-015369-72cjogxz 7186 5 age age NN cord-015369-72cjogxz 7186 6 , , , cord-015369-72cjogxz 7186 7 previous previous JJ cord-015369-72cjogxz 7186 8 cardiac cardiac NN cord-015369-72cjogxz 7186 9 surgery surgery NN cord-015369-72cjogxz 7186 10 , , , cord-015369-72cjogxz 7186 11 additional additional JJ cord-015369-72cjogxz 7186 12 procedures procedure NNS cord-015369-72cjogxz 7186 13 at at IN cord-015369-72cjogxz 7186 14 the the DT cord-015369-72cjogxz 7186 15 time time NN cord-015369-72cjogxz 7186 16 of of IN cord-015369-72cjogxz 7186 17 valve valve NN cord-015369-72cjogxz 7186 18 replacement replacement NN cord-015369-72cjogxz 7186 19 , , , cord-015369-72cjogxz 7186 20 NYHA NYHA NNP cord-015369-72cjogxz 7186 21 IV IV NNP cord-015369-72cjogxz 7186 22 and and CC cord-015369-72cjogxz 7186 23 severely severely RB cord-015369-72cjogxz 7186 24 impaired impaired JJ cord-015369-72cjogxz 7186 25 LVEF LVEF NNP cord-015369-72cjogxz 7186 26 to to TO cord-015369-72cjogxz 7186 27 be be VB cord-015369-72cjogxz 7186 28 independent independent JJ cord-015369-72cjogxz 7186 29 predictors predictor NNS cord-015369-72cjogxz 7186 30 of of IN cord-015369-72cjogxz 7186 31 survival survival NN cord-015369-72cjogxz 7186 32 . . . cord-015369-72cjogxz 7187 1 Mechanical mechanical JJ cord-015369-72cjogxz 7187 2 aortic aortic JJ cord-015369-72cjogxz 7187 3 valve valve NN cord-015369-72cjogxz 7187 4 replacement replacement NN cord-015369-72cjogxz 7187 5 in in IN cord-015369-72cjogxz 7187 6 the the DT cord-015369-72cjogxz 7187 7 small small JJ cord-015369-72cjogxz 7187 8 aortic aortic JJ cord-015369-72cjogxz 7187 9 root root NN cord-015369-72cjogxz 7187 10 is be VBZ cord-015369-72cjogxz 7187 11 associated associate VBN cord-015369-72cjogxz 7187 12 with with IN cord-015369-72cjogxz 7187 13 substantial substantial JJ cord-015369-72cjogxz 7187 14 perioperative perioperative JJ cord-015369-72cjogxz 7187 15 mortality mortality NN cord-015369-72cjogxz 7187 16 . . . cord-015369-72cjogxz 7188 1 Nevertheless nevertheless RB cord-015369-72cjogxz 7188 2 , , , cord-015369-72cjogxz 7188 3 long long JJ cord-015369-72cjogxz 7188 4 - - HYPH cord-015369-72cjogxz 7188 5 term term NN cord-015369-72cjogxz 7188 6 outcome outcome NN cord-015369-72cjogxz 7188 7 is be VBZ cord-015369-72cjogxz 7188 8 satisfying satisfying JJ cord-015369-72cjogxz 7188 9 . . . cord-015369-72cjogxz 7189 1 Because because IN cord-015369-72cjogxz 7189 2 the the DT cord-015369-72cjogxz 7189 3 type type NN cord-015369-72cjogxz 7189 4 of of IN cord-015369-72cjogxz 7189 5 prosthesis prosthesis NN cord-015369-72cjogxz 7189 6 does do VBZ cord-015369-72cjogxz 7189 7 not not RB cord-015369-72cjogxz 7189 8 predict predict VB cord-015369-72cjogxz 7189 9 outcome outcome NN cord-015369-72cjogxz 7189 10 in in IN cord-015369-72cjogxz 7189 11 the the DT cord-015369-72cjogxz 7189 12 multivariate multivariate JJ cord-015369-72cjogxz 7189 13 Cox Cox NNP cord-015369-72cjogxz 7189 14 model model NN cord-015369-72cjogxz 7189 15 , , , cord-015369-72cjogxz 7189 16 we -PRON- PRP cord-015369-72cjogxz 7189 17 conclude conclude VBP cord-015369-72cjogxz 7189 18 that that IN cord-015369-72cjogxz 7189 19 use use NN cord-015369-72cjogxz 7189 20 of of IN cord-015369-72cjogxz 7189 21 the the DT cord-015369-72cjogxz 7189 22 Top Top NNP cord-015369-72cjogxz 7189 23 Hat Hat NNP cord-015369-72cjogxz 7189 24 prosthesis prosthesis NN cord-015369-72cjogxz 7189 25 can can MD cord-015369-72cjogxz 7189 26 be be VB cord-015369-72cjogxz 7189 27 recommended recommend VBN cord-015369-72cjogxz 7189 28 for for IN cord-015369-72cjogxz 7189 29 the the DT cord-015369-72cjogxz 7189 30 challenging challenging JJ cord-015369-72cjogxz 7189 31 cohort cohort NN cord-015369-72cjogxz 7189 32 of of IN cord-015369-72cjogxz 7189 33 patients patient NNS cord-015369-72cjogxz 7189 34 with with IN cord-015369-72cjogxz 7189 35 a a DT cord-015369-72cjogxz 7189 36 small small JJ cord-015369-72cjogxz 7189 37 aortic aortic JJ cord-015369-72cjogxz 7189 38 root root NN cord-015369-72cjogxz 7189 39 . . . cord-015369-72cjogxz 7190 1 Klinische Klinische NNP cord-015369-72cjogxz 7190 2 Abteilung Abteilung NNP cord-015369-72cjogxz 7190 3 für für IN cord-015369-72cjogxz 7190 4 Herz Herz NNP cord-015369-72cjogxz 7190 5 - - HYPH cord-015369-72cjogxz 7190 6 Thoraxchirurgie Thoraxchirurgie NNP cord-015369-72cjogxz 7190 7 , , , cord-015369-72cjogxz 7190 8 Wien Wien NNP cord-015369-72cjogxz 7190 9 , , , cord-015369-72cjogxz 7191 1 Austria Austria NNP cord-015369-72cjogxz 7191 2 Stumpfe Stumpfe NNP cord-015369-72cjogxz 7191 3 Thoraxtraumen Thoraxtraumen NNP cord-015369-72cjogxz 7191 4 können können NNP cord-015369-72cjogxz 7191 5 unabhängig unabhängig NNS cord-015369-72cjogxz 7191 6 vom vom NNP cord-015369-72cjogxz 7191 7 Unfallmechanismus Unfallmechanismus NNP cord-015369-72cjogxz 7191 8 und und IN cord-015369-72cjogxz 7191 9 Schweregrad Schweregrad NNP cord-015369-72cjogxz 7191 10 des des NNP cord-015369-72cjogxz 7191 11 Traumas Traumas NNP cord-015369-72cjogxz 7191 12 zu zu NNP cord-015369-72cjogxz 7191 13 Mitralklappeninsuffizienz Mitralklappeninsuffizienz NNP cord-015369-72cjogxz 7191 14 führen führen NNP cord-015369-72cjogxz 7191 15 . . . cord-015369-72cjogxz 7192 1 Die die VB cord-015369-72cjogxz 7192 2 Unterscheidung Unterscheidung NNP cord-015369-72cjogxz 7192 3 zwischen zwischen NNP cord-015369-72cjogxz 7192 4 vorbestehender vorbestehender NN cord-015369-72cjogxz 7192 5 Schädigung Schädigung NNP cord-015369-72cjogxz 7193 1 und und NNP cord-015369-72cjogxz 7193 2 traumatischer traumatischer NNP cord-015369-72cjogxz 7194 1 Genese Genese NNP cord-015369-72cjogxz 7194 2 ist ist NNP cord-015369-72cjogxz 7195 1 unter unter NNP cord-015369-72cjogxz 7195 2 begutachtungsmedizinischen begutachtungsmedizinischen NNP cord-015369-72cjogxz 7195 3 Aspekten Aspekten NNP cord-015369-72cjogxz 7195 4 von von NNP cord-015369-72cjogxz 7195 5 großer großer NNP cord-015369-72cjogxz 7195 6 Bedeutung Bedeutung NNP cord-015369-72cjogxz 7195 7 . . . cord-015369-72cjogxz 7196 1 Kasuistik Kasuistik NNP cord-015369-72cjogxz 7196 2 : : : cord-015369-72cjogxz 7197 1 Ein Ein NNP cord-015369-72cjogxz 7198 1 35 35 CD cord-015369-72cjogxz 7198 2 jähriger jähriger IN cord-015369-72cjogxz 7198 3 Gendarm Gendarm NNP cord-015369-72cjogxz 7198 4 wurde wurde NNP cord-015369-72cjogxz 7198 5 i -PRON- PRP cord-015369-72cjogxz 7198 6 m be VBP cord-015369-72cjogxz 7198 7 Rahmen Rahmen NNP cord-015369-72cjogxz 7198 8 einer einer NNP cord-015369-72cjogxz 7198 9 Ü Ü NNP cord-015369-72cjogxz 7198 10 bung bung NN cord-015369-72cjogxz 7198 11 in in IN cord-015369-72cjogxz 7198 12 Knie Knie NNP cord-015369-72cjogxz 7198 13 - - HYPH cord-015369-72cjogxz 7198 14 Ellenbogen Ellenbogen NNP cord-015369-72cjogxz 7198 15 - - HYPH cord-015369-72cjogxz 7198 16 Position Position NNP cord-015369-72cjogxz 7198 17 mit mit NNP cord-015369-72cjogxz 7198 18 auf auf NNP cord-015369-72cjogxz 7198 19 dem dem NNP cord-015369-72cjogxz 7199 1 Rü rü RB cord-015369-72cjogxz 7199 2 cken cken VBN cord-015369-72cjogxz 7199 3 stehendem stehendem NNP cord-015369-72cjogxz 7200 1 Kollegen Kollegen NNP cord-015369-72cjogxz 7200 2 von von NNP cord-015369-72cjogxz 7200 3 einer einer NNP cord-015369-72cjogxz 7201 1 Mauer Mauer NNP cord-015369-72cjogxz 7201 2 aus aus NNP cord-015369-72cjogxz 7201 3 einer einer NNP cord-015369-72cjogxz 7201 4 Höhe Höhe NNP cord-015369-72cjogxz 7201 5 von von NNP cord-015369-72cjogxz 7201 6 2 2 CD cord-015369-72cjogxz 7201 7 Meter Meter NNP cord-015369-72cjogxz 7201 8 herab herab NNP cord-015369-72cjogxz 7201 9 fallenden fallenden NNP cord-015369-72cjogxz 7201 10 Sandsäcken Sandsäcken NNP cord-015369-72cjogxz 7201 11 getroffen getroffen NNP cord-015369-72cjogxz 7202 1 und und NNP cord-015369-72cjogxz 7202 2 erlitt erlitt NNP cord-015369-72cjogxz 7202 3 ein ein NNP cord-015369-72cjogxz 7202 4 HWS HWS NNP cord-015369-72cjogxz 7202 5 - - HYPH cord-015369-72cjogxz 7202 6 und und NNP cord-015369-72cjogxz 7202 7 BWS BWS NNP cord-015369-72cjogxz 7202 8 - - HYPH cord-015369-72cjogxz 7202 9 Trauma Trauma NNP cord-015369-72cjogxz 7202 10 . . . cord-015369-72cjogxz 7203 1 Erst Erst NNP cord-015369-72cjogxz 7203 2 16 16 CD cord-015369-72cjogxz 7204 1 Monate Monate NNP cord-015369-72cjogxz 7204 2 später später NNP cord-015369-72cjogxz 7204 3 wurde wurde NNP cord-015369-72cjogxz 7205 1 erstmalig erstmalig NNP cord-015369-72cjogxz 7205 2 ein ein NNP cord-015369-72cjogxz 7205 3 Herzultraschall Herzultraschall NNP cord-015369-72cjogxz 7205 4 durchgefü durchgefü NN cord-015369-72cjogxz 7206 1 hrt hrt NNP cord-015369-72cjogxz 7206 2 und und NNP cord-015369-72cjogxz 7206 3 ein ein NNP cord-015369-72cjogxz 7206 4 Sehnenfadenabriss Sehnenfadenabriss NNP cord-015369-72cjogxz 7206 5 mit mit XX cord-015369-72cjogxz 7206 6 höhergradiger höhergradiger NN cord-015369-72cjogxz 7206 7 Mitralinsuffizienz Mitralinsuffizienz NNP cord-015369-72cjogxz 7206 8 diagnostiziert diagnostiziert NNP cord-015369-72cjogxz 7206 9 und und NNP cord-015369-72cjogxz 7206 10 drei drei NNP cord-015369-72cjogxz 7207 1 Jahre Jahre NNP cord-015369-72cjogxz 7207 2 nach nach NNP cord-015369-72cjogxz 7207 3 dem dem NNP cord-015369-72cjogxz 7207 4 Trauma Trauma NNP cord-015369-72cjogxz 7207 5 ein ein NNP cord-015369-72cjogxz 7207 6 mechanischer mechanischer JJ cord-015369-72cjogxz 7207 7 Herzklappenersatz Herzklappenersatz NNP cord-015369-72cjogxz 7207 8 vorgenommen vorgenomman NNS cord-015369-72cjogxz 7207 9 . . . cord-015369-72cjogxz 7208 1 Als Als NNP cord-015369-72cjogxz 7208 2 häufigste häufigste NN cord-015369-72cjogxz 7209 1 Ursache Ursache NNP cord-015369-72cjogxz 7210 1 fü fü IN cord-015369-72cjogxz 7210 2 r r NN cord-015369-72cjogxz 7210 3 eine eine NN cord-015369-72cjogxz 7210 4 posttraumatische posttraumatische NN cord-015369-72cjogxz 7210 5 Insuffizienz Insuffizienz NNP cord-015369-72cjogxz 7210 6 der der NNP cord-015369-72cjogxz 7210 7 Mitralklappe Mitralklappe NNP cord-015369-72cjogxz 7210 8 besteht besteht NNP cord-015369-72cjogxz 7210 9 ein ein NNP cord-015369-72cjogxz 7210 10 Papillarmuskel Papillarmuskel NNP cord-015369-72cjogxz 7210 11 - - HYPH cord-015369-72cjogxz 7210 12 Abriss Abriss NNP cord-015369-72cjogxz 7210 13 , , , cord-015369-72cjogxz 7210 14 seltener seltener NNP cord-015369-72cjogxz 7210 15 ein ein NNP cord-015369-72cjogxz 7210 16 ausschließliches ausschließliches NNP cord-015369-72cjogxz 7210 17 Trauma Trauma NNP cord-015369-72cjogxz 7210 18 der der NN cord-015369-72cjogxz 7210 19 Sehnenfäden Sehnenfäden NNP cord-015369-72cjogxz 7210 20 . . . cord-015369-72cjogxz 7211 1 Die die VB cord-015369-72cjogxz 7211 2 Literatur Literatur NNP cord-015369-72cjogxz 7211 3 der der NN cord-015369-72cjogxz 7211 4 Jahre Jahre NNP cord-015369-72cjogxz 7211 5 1964 1964 CD cord-015369-72cjogxz 7212 1 bis bis NNP cord-015369-72cjogxz 7212 2 2005 2005 CD cord-015369-72cjogxz 7212 3 enthält enthält NNP cord-015369-72cjogxz 7213 1 14 14 CD cord-015369-72cjogxz 7213 2 berichtete berichtete NN cord-015369-72cjogxz 7213 3 Fälle Fälle NNP cord-015369-72cjogxz 7213 4 von von NNP cord-015369-72cjogxz 7213 5 isoliertem isoliertem NN cord-015369-72cjogxz 7214 1 Abriss Abriss NNP cord-015369-72cjogxz 7214 2 von von NNP cord-015369-72cjogxz 7214 3 Sehnenfäden Sehnenfäden NNP cord-015369-72cjogxz 7214 4 mit mit NNP cord-015369-72cjogxz 7214 5 höhergradiger höhergradiger NN cord-015369-72cjogxz 7214 6 Mitralinsuffizienz Mitralinsuffizienz NNP cord-015369-72cjogxz 7214 7 , , , cord-015369-72cjogxz 7214 8 zwei zwei NNP cord-015369-72cjogxz 7214 9 davon davon NNP cord-015369-72cjogxz 7214 10 als als NNP cord-015369-72cjogxz 7214 11 autoptische autoptische NNP cord-015369-72cjogxz 7215 1 Diagnose diagnose VB cord-015369-72cjogxz 7215 2 . . . cord-015369-72cjogxz 7216 1 Das Das NNP cord-015369-72cjogxz 7216 2 Alter Alter NNP cord-015369-72cjogxz 7216 3 der der NN cord-015369-72cjogxz 7216 4 in in IN cord-015369-72cjogxz 7216 5 86 86 CD cord-015369-72cjogxz 7216 6 % % NN cord-015369-72cjogxz 7217 1 männlichen männlichen NNP cord-015369-72cjogxz 7217 2 Betroffenen Betroffenen NNP cord-015369-72cjogxz 7217 3 lag lag NNP cord-015369-72cjogxz 7217 4 zwischen zwischen NNP cord-015369-72cjogxz 7217 5 7 7 CD cord-015369-72cjogxz 7217 6 und und NN cord-015369-72cjogxz 7217 7 64 64 CD cord-015369-72cjogxz 7217 8 Jahren Jahren NNP cord-015369-72cjogxz 7217 9 , , , cord-015369-72cjogxz 7217 10 i -PRON- PRP cord-015369-72cjogxz 7217 11 m be VBP cord-015369-72cjogxz 7217 12 Mittel Mittel NNP cord-015369-72cjogxz 7217 13 40,5 40,5 CD cord-015369-72cjogxz 7217 14 Jahre Jahre NNP cord-015369-72cjogxz 7217 15 . . . cord-015369-72cjogxz 7218 1 Als Als NNP cord-015369-72cjogxz 7218 2 Unfallursache Unfallursache NNP cord-015369-72cjogxz 7218 3 dominierten dominierten NN cord-015369-72cjogxz 7218 4 Verkehrsunfälle Verkehrsunfälle NNP cord-015369-72cjogxz 7218 5 unterschiedlicher unterschiedlicher NN cord-015369-72cjogxz 7218 6 Art Art NNP cord-015369-72cjogxz 7218 7 ( ( -LRB- cord-015369-72cjogxz 7218 8 n n NNP cord-015369-72cjogxz 7218 9 ¼ ¼ NNP cord-015369-72cjogxz 7218 10 10 10 CD cord-015369-72cjogxz 7218 11 ; ; : cord-015369-72cjogxz 7218 12 71 71 CD cord-015369-72cjogxz 7218 13 % % NN cord-015369-72cjogxz 7218 14 ) ) -RRB- cord-015369-72cjogxz 7218 15 und und RB cord-015369-72cjogxz 7218 16 in in IN cord-015369-72cjogxz 7219 1 Einzelfällen Einzelfällen NNP cord-015369-72cjogxz 7219 2 Sturz Sturz NNP cord-015369-72cjogxz 7219 3 aus aus NNP cord-015369-72cjogxz 7219 4 2 2 CD cord-015369-72cjogxz 7219 5 Meter Meter NNP cord-015369-72cjogxz 7219 6 Höhe Höhe NNP cord-015369-72cjogxz 7219 7 , , , cord-015369-72cjogxz 7219 8 gegen gegen NNP cord-015369-72cjogxz 7219 9 ein ein NNP cord-015369-72cjogxz 7219 10 Boot Boot NNP cord-015369-72cjogxz 7219 11 oder oder NN cord-015369-72cjogxz 7219 12 vom vom NNP cord-015369-72cjogxz 7219 13 Pferd Pferd NNP cord-015369-72cjogxz 7219 14 sowie sowie NNP cord-015369-72cjogxz 7219 15 ein ein NNP cord-015369-72cjogxz 7219 16 Pferdetritt Pferdetritt NNP cord-015369-72cjogxz 7219 17 . . . cord-015369-72cjogxz 7220 1 Das Das NNP cord-015369-72cjogxz 7220 2 Intervall Intervall NNP cord-015369-72cjogxz 7220 3 zwischen zwischen FW cord-015369-72cjogxz 7220 4 Ereignis Ereignis NNP cord-015369-72cjogxz 7221 1 und und IN cord-015369-72cjogxz 7221 2 operativer operativer NNP cord-015369-72cjogxz 7221 3 Versorgung Versorgung NNP cord-015369-72cjogxz 7221 4 durch durch NNP cord-015369-72cjogxz 7221 5 Rekonstruktion Rekonstruktion NNP cord-015369-72cjogxz 7221 6 oder oder NN cord-015369-72cjogxz 7221 7 prothetischen prothetischen NNP cord-015369-72cjogxz 7221 8 Ersatz ersatz JJ cord-015369-72cjogxz 7221 9 lag lag VBP cord-015369-72cjogxz 7221 10 zwischen zwischen NNP cord-015369-72cjogxz 7221 11 4 4 CD cord-015369-72cjogxz 7221 12 Tagen Tagen NNP cord-015369-72cjogxz 7221 13 und und IN cord-015369-72cjogxz 7221 14 24 24 CD cord-015369-72cjogxz 7221 15 Jahren Jahren NNP cord-015369-72cjogxz 7221 16 , , , cord-015369-72cjogxz 7221 17 in in IN cord-015369-72cjogxz 7221 18 67 67 CD cord-015369-72cjogxz 7221 19 % % NN cord-015369-72cjogxz 7221 20 ( ( -LRB- cord-015369-72cjogxz 7221 21 8 8 CD cord-015369-72cjogxz 7221 22 von von NNP cord-015369-72cjogxz 7221 23 12 12 CD cord-015369-72cjogxz 7221 24 ) ) -RRB- cord-015369-72cjogxz 7221 25 jedoch jedoch NNP cord-015369-72cjogxz 7221 26 unter unter NNP cord-015369-72cjogxz 7221 27 einem einem NNP cord-015369-72cjogxz 7221 28 Monat Monat NNP cord-015369-72cjogxz 7221 29 . . . cord-015369-72cjogxz 7222 1 Die die VB cord-015369-72cjogxz 7222 2 Frage Frage NNP cord-015369-72cjogxz 7222 3 der der NN cord-015369-72cjogxz 7222 4 Ursächlichkeit Ursächlichkeit NNP cord-015369-72cjogxz 7222 5 ist ist NN cord-015369-72cjogxz 7222 6 meist meist NN cord-015369-72cjogxz 7222 7 retrospektiv retrospektiv JJ cord-015369-72cjogxz 7222 8 zu zu NNP cord-015369-72cjogxz 7222 9 beantworten beantworten NNP cord-015369-72cjogxz 7222 10 . . . cord-015369-72cjogxz 7223 1 Häufig Häufig NNP cord-015369-72cjogxz 7223 2 sind sind NN cord-015369-72cjogxz 7223 3 fokussierte fokussierte NN cord-015369-72cjogxz 7223 4 Untersuchungsbefunde Untersuchungsbefunde NNP cord-015369-72cjogxz 7223 5 nicht nicht NNP cord-015369-72cjogxz 7223 6 verfügbar verfügbar NN cord-015369-72cjogxz 7223 7 und und IN cord-015369-72cjogxz 7223 8 bleibt bleibt NNP cord-015369-72cjogxz 7223 9 die die VB cord-015369-72cjogxz 7223 10 Genese Genese NNP cord-015369-72cjogxz 7223 11 letztlich letztlich VBZ cord-015369-72cjogxz 7223 12 spekulativ spekulativ RB cord-015369-72cjogxz 7223 13 . . . cord-015369-72cjogxz 7224 1 Daher Daher NNP cord-015369-72cjogxz 7224 2 sollten sollten NNP cord-015369-72cjogxz 7224 3 nach nach NNP cord-015369-72cjogxz 7224 4 jedem jedem NNP cord-015369-72cjogxz 7224 5 Thoraxtrauma Thoraxtrauma NNP cord-015369-72cjogxz 7225 1 eine eine NNP cord-015369-72cjogxz 7225 2 Echokardiographie Echokardiographie NNP cord-015369-72cjogxz 7226 1 und und NNP cord-015369-72cjogxz 7226 2 anlässlich anlässlich NNP cord-015369-72cjogxz 7226 3 jeder jeder NNP cord-015369-72cjogxz 7226 4 Herzoperation Herzoperation NNP cord-015369-72cjogxz 7226 5 nach nach NNP cord-015369-72cjogxz 7226 6 anamnestischem anamnestischem NNP cord-015369-72cjogxz 7226 7 Ereignis Ereignis NNP cord-015369-72cjogxz 7226 8 eine eine NNP cord-015369-72cjogxz 7226 9 detaillierte detaillierte NNP cord-015369-72cjogxz 7226 10 makroskopische makroskopische NN cord-015369-72cjogxz 7227 1 und und NNP cord-015369-72cjogxz 7228 1 histologische histologische NNP cord-015369-72cjogxz 7228 2 Befundung Befundung NNP cord-015369-72cjogxz 7228 3 durchgeführt durchgeführt NN cord-015369-72cjogxz 7228 4 werden werden NNP cord-015369-72cjogxz 7228 5 . . . cord-015369-72cjogxz 7229 1 Simultaneous simultaneous JJ cord-015369-72cjogxz 7229 2 mitral mitral JJ cord-015369-72cjogxz 7229 3 valve valve NN cord-015369-72cjogxz 7229 4 and and CC cord-015369-72cjogxz 7229 5 lung lung NN cord-015369-72cjogxz 7229 6 surgery surgery NN cord-015369-72cjogxz 7229 7 for for IN cord-015369-72cjogxz 7229 8 complicated complicated JJ cord-015369-72cjogxz 7229 9 endocarditis endocarditis NN cord-015369-72cjogxz 7229 10 and and CC cord-015369-72cjogxz 7229 11 abscessing abscesse VBG cord-015369-72cjogxz 7229 12 pneumonia pneumonia NN cord-015369-72cjogxz 7229 13 over over IN cord-015369-72cjogxz 7229 14 a a DT cord-015369-72cjogxz 7229 15 thoracotomy thoracotomy NN cord-015369-72cjogxz 7229 16 approach approach NN cord-015369-72cjogxz 7230 1 A a DT cord-015369-72cjogxz 7230 2 48-year 48-year JJ cord-015369-72cjogxz 7230 3 - - HYPH cord-015369-72cjogxz 7230 4 old old JJ cord-015369-72cjogxz 7230 5 man man NN cord-015369-72cjogxz 7230 6 developed develop VBD cord-015369-72cjogxz 7230 7 severe severe JJ cord-015369-72cjogxz 7230 8 sepsis sepsis NN cord-015369-72cjogxz 7230 9 after after IN cord-015369-72cjogxz 7230 10 a a DT cord-015369-72cjogxz 7230 11 blunt blunt JJ cord-015369-72cjogxz 7230 12 chest chest NN cord-015369-72cjogxz 7230 13 trauma trauma NN cord-015369-72cjogxz 7230 14 . . . cord-015369-72cjogxz 7231 1 The the DT cord-015369-72cjogxz 7231 2 patient patient NN cord-015369-72cjogxz 7231 3 suffered suffer VBD cord-015369-72cjogxz 7231 4 from from IN cord-015369-72cjogxz 7231 5 presternal presternal JJ cord-015369-72cjogxz 7231 6 and and CC cord-015369-72cjogxz 7231 7 cervical cervical JJ cord-015369-72cjogxz 7231 8 abscesses abscess NNS cord-015369-72cjogxz 7231 9 , , , cord-015369-72cjogxz 7231 10 mediastinitis mediastinitis NN cord-015369-72cjogxz 7231 11 , , , cord-015369-72cjogxz 7231 12 septic septic JJ cord-015369-72cjogxz 7231 13 arthritis arthritis NN cord-015369-72cjogxz 7231 14 of of IN cord-015369-72cjogxz 7231 15 the the DT cord-015369-72cjogxz 7231 16 right right JJ cord-015369-72cjogxz 7231 17 shoulder shoulder NN cord-015369-72cjogxz 7231 18 , , , cord-015369-72cjogxz 7231 19 abscesses abscess NNS cord-015369-72cjogxz 7231 20 in in IN cord-015369-72cjogxz 7231 21 the the DT cord-015369-72cjogxz 7231 22 right right JJ cord-015369-72cjogxz 7231 23 and and CC cord-015369-72cjogxz 7231 24 severe severe JJ cord-015369-72cjogxz 7231 25 infective infective JJ cord-015369-72cjogxz 7231 26 endocarditis endocarditis NN cord-015369-72cjogxz 7231 27 of of IN cord-015369-72cjogxz 7231 28 the the DT cord-015369-72cjogxz 7231 29 mitral mitral JJ cord-015369-72cjogxz 7231 30 valve valve NN cord-015369-72cjogxz 7231 31 . . . cord-015369-72cjogxz 7232 1 After after IN cord-015369-72cjogxz 7232 2 subcutaneous subcutaneous JJ cord-015369-72cjogxz 7232 3 and and CC cord-015369-72cjogxz 7232 4 mediastinal mediastinal JJ cord-015369-72cjogxz 7232 5 abscess abscess NN cord-015369-72cjogxz 7232 6 drainage drainage NN cord-015369-72cjogxz 7232 7 , , , cord-015369-72cjogxz 7232 8 hemodynamic hemodynamic JJ cord-015369-72cjogxz 7232 9 stabilisation stabilisation NN cord-015369-72cjogxz 7232 10 , , , cord-015369-72cjogxz 7232 11 and and CC cord-015369-72cjogxz 7232 12 control control NN cord-015369-72cjogxz 7232 13 of of IN cord-015369-72cjogxz 7232 14 sepsis sepsis NN cord-015369-72cjogxz 7232 15 , , , cord-015369-72cjogxz 7232 16 biological biological JJ cord-015369-72cjogxz 7232 17 mitral mitral JJ cord-015369-72cjogxz 7232 18 valve valve NN cord-015369-72cjogxz 7232 19 replacement replacement NN cord-015369-72cjogxz 7232 20 and and CC cord-015369-72cjogxz 7232 21 concomitant concomitant JJ cord-015369-72cjogxz 7232 22 resection resection NN cord-015369-72cjogxz 7232 23 of of IN cord-015369-72cjogxz 7232 24 the the DT cord-015369-72cjogxz 7232 25 right right JJ cord-015369-72cjogxz 7232 26 lower low JJR cord-015369-72cjogxz 7232 27 pulmonary pulmonary JJ cord-015369-72cjogxz 7232 28 lobe lobe NN cord-015369-72cjogxz 7232 29 were be VBD cord-015369-72cjogxz 7232 30 performed perform VBN cord-015369-72cjogxz 7232 31 over over IN cord-015369-72cjogxz 7232 32 a a DT cord-015369-72cjogxz 7232 33 muscle muscle NN cord-015369-72cjogxz 7232 34 sparing spare VBG cord-015369-72cjogxz 7232 35 15 15 CD cord-015369-72cjogxz 7232 36 cm cm NN cord-015369-72cjogxz 7232 37 right right JJ cord-015369-72cjogxz 7232 38 anterior anterior JJ cord-015369-72cjogxz 7232 39 - - HYPH cord-015369-72cjogxz 7232 40 lateral lateral JJ cord-015369-72cjogxz 7232 41 thoracotomy thoracotomy NN cord-015369-72cjogxz 7232 42 . . . cord-015369-72cjogxz 7233 1 Restoration restoration NN cord-015369-72cjogxz 7233 2 of of IN cord-015369-72cjogxz 7233 3 the the DT cord-015369-72cjogxz 7233 4 shoulder shoulder NN cord-015369-72cjogxz 7233 5 could could MD cord-015369-72cjogxz 7233 6 be be VB cord-015369-72cjogxz 7233 7 performed perform VBN cord-015369-72cjogxz 7233 8 22 22 CD cord-015369-72cjogxz 7233 9 days day NNS cord-015369-72cjogxz 7233 10 later later RB cord-015369-72cjogxz 7233 11 . . . cord-015369-72cjogxz 7234 1 The the DT cord-015369-72cjogxz 7234 2 patient patient NN cord-015369-72cjogxz 7234 3 was be VBD cord-015369-72cjogxz 7234 4 discharged discharge VBN cord-015369-72cjogxz 7234 5 after after IN cord-015369-72cjogxz 7234 6 4 4 CD cord-015369-72cjogxz 7234 7 weeks week NNS cord-015369-72cjogxz 7234 8 and and CC cord-015369-72cjogxz 7234 9 is be VBZ cord-015369-72cjogxz 7234 10 well well RB cord-015369-72cjogxz 7234 11 one one CD cord-015369-72cjogxz 7234 12 year year NN cord-015369-72cjogxz 7234 13 after after IN cord-015369-72cjogxz 7234 14 surgery surgery NN cord-015369-72cjogxz 7234 15 . . . cord-015369-72cjogxz 7235 1 ASD ASD NNP cord-015369-72cjogxz 7235 2 repair repair NN cord-015369-72cjogxz 7235 3 after after IN cord-015369-72cjogxz 7235 4 a a DT cord-015369-72cjogxz 7235 5 10-month 10-month JJ cord-015369-72cjogxz 7235 6 treatment treatment NN cord-015369-72cjogxz 7235 7 with with IN cord-015369-72cjogxz 7235 8 Bosentan Bosentan NNP cord-015369-72cjogxz 7235 9 in in IN cord-015369-72cjogxz 7235 10 a a DT cord-015369-72cjogxz 7235 11 patient patient NN cord-015369-72cjogxz 7235 12 with with IN cord-015369-72cjogxz 7235 13 severe severe JJ cord-015369-72cjogxz 7235 14 pulmonary pulmonary JJ cord-015369-72cjogxz 7235 15 arterial arterial JJ cord-015369-72cjogxz 7235 16 hypertension hypertension NN cord-015369-72cjogxz 7235 17 Large large JJ cord-015369-72cjogxz 7235 18 congenital congenital JJ cord-015369-72cjogxz 7235 19 type type NN cord-015369-72cjogxz 7235 20 II II NNP cord-015369-72cjogxz 7235 21 atrial atrial JJ cord-015369-72cjogxz 7235 22 septal septal JJ cord-015369-72cjogxz 7235 23 defect defect NN cord-015369-72cjogxz 7235 24 ( ( -LRB- cord-015369-72cjogxz 7235 25 ASD ASD NNP cord-015369-72cjogxz 7235 26 II II NNP cord-015369-72cjogxz 7235 27 ) ) -RRB- cord-015369-72cjogxz 7235 28 can can MD cord-015369-72cjogxz 7235 29 lead lead VB cord-015369-72cjogxz 7235 30 to to IN cord-015369-72cjogxz 7235 31 precapillary precapillary JJ cord-015369-72cjogxz 7235 32 pulmonary pulmonary JJ cord-015369-72cjogxz 7235 33 hypertension hypertension NN cord-015369-72cjogxz 7235 34 ( ( -LRB- cord-015369-72cjogxz 7235 35 PAH PAH NNP cord-015369-72cjogxz 7235 36 ) ) -RRB- cord-015369-72cjogxz 7235 37 if if IN cord-015369-72cjogxz 7235 38 not not RB cord-015369-72cjogxz 7235 39 repaired repair VBN cord-015369-72cjogxz 7235 40 in in IN cord-015369-72cjogxz 7235 41 early early JJ cord-015369-72cjogxz 7235 42 childhood childhood NN cord-015369-72cjogxz 7235 43 . . . cord-015369-72cjogxz 7236 1 Once once IN cord-015369-72cjogxz 7236 2 severe severe JJ cord-015369-72cjogxz 7236 3 pulmonary pulmonary JJ cord-015369-72cjogxz 7236 4 hypertension hypertension NN cord-015369-72cjogxz 7236 5 or or CC cord-015369-72cjogxz 7236 6 Eisenmenger Eisenmenger NNP cord-015369-72cjogxz 7236 7 's 's POS cord-015369-72cjogxz 7236 8 syndrome syndrome NN cord-015369-72cjogxz 7236 9 have have VBP cord-015369-72cjogxz 7236 10 developed develop VBN cord-015369-72cjogxz 7236 11 , , , cord-015369-72cjogxz 7236 12 ASD ASD NNP cord-015369-72cjogxz 7236 13 closure closure NN cord-015369-72cjogxz 7236 14 is be VBZ cord-015369-72cjogxz 7236 15 problematic problematic JJ cord-015369-72cjogxz 7236 16 due due JJ cord-015369-72cjogxz 7236 17 the the DT cord-015369-72cjogxz 7236 18 increased increase VBN cord-015369-72cjogxz 7236 19 risk risk NN cord-015369-72cjogxz 7236 20 of of IN cord-015369-72cjogxz 7236 21 right right JJ cord-015369-72cjogxz 7236 22 ventricular ventricular JJ cord-015369-72cjogxz 7236 23 failure failure NN cord-015369-72cjogxz 7236 24 and and CC cord-015369-72cjogxz 7236 25 pulmonary pulmonary JJ cord-015369-72cjogxz 7236 26 hypertensive hypertensive JJ cord-015369-72cjogxz 7236 27 crisis crisis NN cord-015369-72cjogxz 7236 28 . . . cord-015369-72cjogxz 7237 1 However however RB cord-015369-72cjogxz 7237 2 , , , cord-015369-72cjogxz 7237 3 single single JJ cord-015369-72cjogxz 7237 4 case case NN cord-015369-72cjogxz 7237 5 reports report NNS cord-015369-72cjogxz 7237 6 have have VBP cord-015369-72cjogxz 7237 7 demonstrated demonstrate VBN cord-015369-72cjogxz 7237 8 that that IN cord-015369-72cjogxz 7237 9 a a DT cord-015369-72cjogxz 7237 10 surgical surgical JJ cord-015369-72cjogxz 7237 11 correction correction NN cord-015369-72cjogxz 7237 12 of of IN cord-015369-72cjogxz 7237 13 an an DT cord-015369-72cjogxz 7237 14 ASD ASD NNP cord-015369-72cjogxz 7237 15 is be VBZ cord-015369-72cjogxz 7237 16 feasible feasible JJ cord-015369-72cjogxz 7237 17 , , , cord-015369-72cjogxz 7237 18 but but CC cord-015369-72cjogxz 7237 19 requires require VBZ cord-015369-72cjogxz 7237 20 long long JJ cord-015369-72cjogxz 7237 21 - - HYPH cord-015369-72cjogxz 7237 22 time time NN cord-015369-72cjogxz 7237 23 pre pre JJ cord-015369-72cjogxz 7237 24 - - JJ cord-015369-72cjogxz 7237 25 and and CC cord-015369-72cjogxz 7237 26 post post JJ cord-015369-72cjogxz 7237 27 - - JJ cord-015369-72cjogxz 7237 28 operative operative JJ cord-015369-72cjogxz 7237 29 prostacycline prostacycline NN cord-015369-72cjogxz 7237 30 treatment treatment NN cord-015369-72cjogxz 7237 31 . . . cord-015369-72cjogxz 7238 1 We -PRON- PRP cord-015369-72cjogxz 7238 2 report report VBP cord-015369-72cjogxz 7238 3 the the DT cord-015369-72cjogxz 7238 4 case case NN cord-015369-72cjogxz 7238 5 of of IN cord-015369-72cjogxz 7238 6 a a DT cord-015369-72cjogxz 7238 7 patient patient NN cord-015369-72cjogxz 7238 8 with with IN cord-015369-72cjogxz 7238 9 ASD ASD NNP cord-015369-72cjogxz 7238 10 II II NNP cord-015369-72cjogxz 7238 11 ( ( -LRB- cord-015369-72cjogxz 7238 12 15 15 CD cord-015369-72cjogxz 7238 13 Â â CD cord-015369-72cjogxz 7238 14 36 36 CD cord-015369-72cjogxz 7238 15 mm mm NN cord-015369-72cjogxz 7238 16 ) ) -RRB- cord-015369-72cjogxz 7238 17 and and CC cord-015369-72cjogxz 7238 18 severe severe JJ cord-015369-72cjogxz 7238 19 pulmonary pulmonary JJ cord-015369-72cjogxz 7238 20 hypertension hypertension NN cord-015369-72cjogxz 7238 21 ( ( -LRB- cord-015369-72cjogxz 7238 22 mPAP mpap NN cord-015369-72cjogxz 7238 23 54 54 CD cord-015369-72cjogxz 7238 24 mmHg mmHg NNS cord-015369-72cjogxz 7238 25 ) ) -RRB- cord-015369-72cjogxz 7238 26 . . . cord-015369-72cjogxz 7239 1 Successful successful JJ cord-015369-72cjogxz 7239 2 Background Background NNP cord-015369-72cjogxz 7239 3 . . . cord-015369-72cjogxz 7240 1 Sternal sternal JJ cord-015369-72cjogxz 7240 2 wire wire NN cord-015369-72cjogxz 7240 3 fixation fixation NN cord-015369-72cjogxz 7240 4 was be VBD cord-015369-72cjogxz 7240 5 first first RB cord-015369-72cjogxz 7240 6 used use VBN cord-015369-72cjogxz 7240 7 in in IN cord-015369-72cjogxz 7240 8 1897 1897 CD cord-015369-72cjogxz 7240 9 and and CC cord-015369-72cjogxz 7240 10 since since IN cord-015369-72cjogxz 7240 11 then then RB cord-015369-72cjogxz 7240 12 was be VBD cord-015369-72cjogxz 7240 13 the the DT cord-015369-72cjogxz 7240 14 preferred preferred JJ cord-015369-72cjogxz 7240 15 method method NN cord-015369-72cjogxz 7240 16 for for IN cord-015369-72cjogxz 7240 17 sternal sternal JJ cord-015369-72cjogxz 7240 18 closure closure NN cord-015369-72cjogxz 7240 19 , , , cord-015369-72cjogxz 7240 20 as as IN cord-015369-72cjogxz 7240 21 it -PRON- PRP cord-015369-72cjogxz 7240 22 is be VBZ cord-015369-72cjogxz 7240 23 inexpensive inexpensive JJ cord-015369-72cjogxz 7240 24 , , , cord-015369-72cjogxz 7240 25 fast fast JJ cord-015369-72cjogxz 7240 26 and and CC cord-015369-72cjogxz 7240 27 effective effective JJ cord-015369-72cjogxz 7240 28 . . . cord-015369-72cjogxz 7241 1 However however RB cord-015369-72cjogxz 7241 2 , , , cord-015369-72cjogxz 7241 3 as as IN cord-015369-72cjogxz 7241 4 cardiac cardiac JJ cord-015369-72cjogxz 7241 5 surgery surgery NN cord-015369-72cjogxz 7241 6 patients patient NNS cord-015369-72cjogxz 7241 7 get get VBP cord-015369-72cjogxz 7241 8 older old JJR cord-015369-72cjogxz 7241 9 and and CC cord-015369-72cjogxz 7241 10 more more RBR cord-015369-72cjogxz 7241 11 debilitated debilitated JJ cord-015369-72cjogxz 7241 12 , , , cord-015369-72cjogxz 7241 13 the the DT cord-015369-72cjogxz 7241 14 risks risk NNS cord-015369-72cjogxz 7241 15 of of IN cord-015369-72cjogxz 7241 16 wire wire NN cord-015369-72cjogxz 7241 17 closure closure NN cord-015369-72cjogxz 7241 18 , , , cord-015369-72cjogxz 7241 19 namely namely RB cord-015369-72cjogxz 7241 20 breaking break VBG cord-015369-72cjogxz 7241 21 or or CC cord-015369-72cjogxz 7241 22 cutting cut VBG cord-015369-72cjogxz 7241 23 through through IN cord-015369-72cjogxz 7241 24 porous porous JJ cord-015369-72cjogxz 7241 25 bone bone NN cord-015369-72cjogxz 7241 26 often often RB cord-015369-72cjogxz 7241 27 resulting result VBG cord-015369-72cjogxz 7241 28 in in IN cord-015369-72cjogxz 7241 29 sternal sternal JJ cord-015369-72cjogxz 7241 30 nonunion nonunion NN cord-015369-72cjogxz 7241 31 and and CC cord-015369-72cjogxz 7241 32 wound wound NN cord-015369-72cjogxz 7241 33 infection infection NN cord-015369-72cjogxz 7241 34 . . . cord-015369-72cjogxz 7242 1 Therefore therefore RB cord-015369-72cjogxz 7242 2 , , , cord-015369-72cjogxz 7242 3 alternatives alternative NNS cord-015369-72cjogxz 7242 4 are be VBP cord-015369-72cjogxz 7242 5 needed need VBN cord-015369-72cjogxz 7242 6 to to TO cord-015369-72cjogxz 7242 7 ensure ensure VB cord-015369-72cjogxz 7242 8 a a DT cord-015369-72cjogxz 7242 9 reliable reliable JJ cord-015369-72cjogxz 7242 10 sternal sternal JJ cord-015369-72cjogxz 7242 11 closure closure NN cord-015369-72cjogxz 7242 12 . . . cord-015369-72cjogxz 7243 1 Methods method NNS cord-015369-72cjogxz 7243 2 . . . cord-015369-72cjogxz 7244 1 During during IN cord-015369-72cjogxz 7244 2 January January NNP cord-015369-72cjogxz 7244 3 to to IN cord-015369-72cjogxz 7244 4 December December NNP cord-015369-72cjogxz 7244 5 2008 2008 CD cord-015369-72cjogxz 7244 6 a a DT cord-015369-72cjogxz 7244 7 total total NN cord-015369-72cjogxz 7244 8 of of IN cord-015369-72cjogxz 7244 9 13 13 CD cord-015369-72cjogxz 7244 10 patients patient NNS cord-015369-72cjogxz 7244 11 with with IN cord-015369-72cjogxz 7244 12 am am NN cord-015369-72cjogxz 7245 1 mean mean UH cord-015369-72cjogxz 7245 2 ES ES NNP cord-015369-72cjogxz 7245 3 of of IN cord-015369-72cjogxz 7245 4 9 9 CD cord-015369-72cjogxz 7246 1 ( ( -LRB- cord-015369-72cjogxz 7246 2 mean mean VB cord-015369-72cjogxz 7246 3 age age NN cord-015369-72cjogxz 7246 4 67.6 67.6 CD cord-015369-72cjogxz 7246 5 years year NNS cord-015369-72cjogxz 7246 6 ) ) -RRB- cord-015369-72cjogxz 7246 7 underwent undergo VBD cord-015369-72cjogxz 7246 8 closure closure NN cord-015369-72cjogxz 7246 9 with with IN cord-015369-72cjogxz 7246 10 the the DT cord-015369-72cjogxz 7246 11 sternal sternal JJ cord-015369-72cjogxz 7246 12 talon talon NNP cord-015369-72cjogxz 7246 13 . . . cord-015369-72cjogxz 7247 1 Indication indication NN cord-015369-72cjogxz 7247 2 was be VBD cord-015369-72cjogxz 7247 3 COPD COPD NNP cord-015369-72cjogxz 7247 4 and and CC cord-015369-72cjogxz 7247 5 adipositas adipositas NNPS cord-015369-72cjogxz 7247 6 in in IN cord-015369-72cjogxz 7247 7 6 6 CD cord-015369-72cjogxz 7247 8 patients patient NNS cord-015369-72cjogxz 7247 9 each each DT cord-015369-72cjogxz 7247 10 , , , cord-015369-72cjogxz 7247 11 delayed delay VBN cord-015369-72cjogxz 7247 12 sternal sternal JJ cord-015369-72cjogxz 7247 13 closure closure NN cord-015369-72cjogxz 7247 14 in in IN cord-015369-72cjogxz 7247 15 2 2 CD cord-015369-72cjogxz 7247 16 , , , cord-015369-72cjogxz 7247 17 parasternal parasternal JJ cord-015369-72cjogxz 7247 18 sternotomy sternotomy NN cord-015369-72cjogxz 7247 19 in in IN cord-015369-72cjogxz 7247 20 3 3 CD cord-015369-72cjogxz 7247 21 and and CC cord-015369-72cjogxz 7247 22 secondary secondary JJ cord-015369-72cjogxz 7247 23 closure closure NN cord-015369-72cjogxz 7247 24 after after IN cord-015369-72cjogxz 7247 25 sternal sternal JJ cord-015369-72cjogxz 7247 26 wound wound NN cord-015369-72cjogxz 7247 27 infection infection NN cord-015369-72cjogxz 7247 28 and and CC cord-015369-72cjogxz 7247 29 V.A.C. V.A.C. NNP cord-015369-72cjogxz 7247 30 therapy therapy NN cord-015369-72cjogxz 7247 31 in in IN cord-015369-72cjogxz 7247 32 2 2 CD cord-015369-72cjogxz 7247 33 patients patient NNS cord-015369-72cjogxz 7247 34 . . . cord-015369-72cjogxz 7248 1 Results result NNS cord-015369-72cjogxz 7248 2 . . . cord-015369-72cjogxz 7249 1 All all DT cord-015369-72cjogxz 7249 2 patients patient NNS cord-015369-72cjogxz 7249 3 had have VBD cord-015369-72cjogxz 7249 4 combined combine VBN cord-015369-72cjogxz 7249 5 procedures procedure NNS cord-015369-72cjogxz 7249 6 ( ( -LRB- cord-015369-72cjogxz 7249 7 CABGx CABGx NNS cord-015369-72cjogxz 7249 8 3 3 CD cord-015369-72cjogxz 7249 9 and and CC cord-015369-72cjogxz 7249 10 AKE AKE NNP cord-015369-72cjogxz 7249 11 or or CC cord-015369-72cjogxz 7249 12 MKR MKR NNP cord-015369-72cjogxz 7249 13 or or CC cord-015369-72cjogxz 7249 14 both both DT cord-015369-72cjogxz 7249 15 ) ) -RRB- cord-015369-72cjogxz 7249 16 with with IN cord-015369-72cjogxz 7249 17 a a DT cord-015369-72cjogxz 7249 18 mean mean JJ cord-015369-72cjogxz 7249 19 operating operating NN cord-015369-72cjogxz 7249 20 time time NN cord-015369-72cjogxz 7249 21 of of IN cord-015369-72cjogxz 7249 22 300 300 CD cord-015369-72cjogxz 7249 23 min min NN cord-015369-72cjogxz 7249 24 . . . cord-015369-72cjogxz 7250 1 The the DT cord-015369-72cjogxz 7250 2 sternal sternal JJ cord-015369-72cjogxz 7250 3 talon talon NN cord-015369-72cjogxz 7250 4 was be VBD cord-015369-72cjogxz 7250 5 easy easy JJ cord-015369-72cjogxz 7250 6 and and CC cord-015369-72cjogxz 7250 7 convenient convenient JJ cord-015369-72cjogxz 7250 8 to to TO cord-015369-72cjogxz 7250 9 use use VB cord-015369-72cjogxz 7250 10 , , , cord-015369-72cjogxz 7250 11 with with IN cord-015369-72cjogxz 7250 12 a a DT cord-015369-72cjogxz 7250 13 mean mean JJ cord-015369-72cjogxz 7250 14 implantation implantation NN cord-015369-72cjogxz 7250 15 time time NN cord-015369-72cjogxz 7250 16 of of IN cord-015369-72cjogxz 7250 17 10 10 CD cord-015369-72cjogxz 7250 18 min min NN cord-015369-72cjogxz 7250 19 . . . cord-015369-72cjogxz 7251 1 None none NN cord-015369-72cjogxz 7251 2 of of IN cord-015369-72cjogxz 7251 3 the the DT cord-015369-72cjogxz 7251 4 patients patient NNS cord-015369-72cjogxz 7251 5 developed develop VBD cord-015369-72cjogxz 7251 6 a a DT cord-015369-72cjogxz 7251 7 sternal sternal JJ cord-015369-72cjogxz 7251 8 nonunion nonunion NN cord-015369-72cjogxz 7251 9 or or CC cord-015369-72cjogxz 7251 10 wound wound VB cord-015369-72cjogxz 7251 11 infection infection NN cord-015369-72cjogxz 7251 12 during during IN cord-015369-72cjogxz 7251 13 follow follow NN cord-015369-72cjogxz 7251 14 up up RP cord-015369-72cjogxz 7251 15 . . . cord-015369-72cjogxz 7252 1 Conclusions conclusion NNS cord-015369-72cjogxz 7252 2 . . . cord-015369-72cjogxz 7253 1 The the DT cord-015369-72cjogxz 7253 2 sternal sternal JJ cord-015369-72cjogxz 7253 3 talon talon NN cord-015369-72cjogxz 7253 4 offers offer VBZ cord-015369-72cjogxz 7253 5 the the DT cord-015369-72cjogxz 7253 6 advantage advantage NN cord-015369-72cjogxz 7253 7 of of IN cord-015369-72cjogxz 7253 8 a a DT cord-015369-72cjogxz 7253 9 rigid rigid JJ cord-015369-72cjogxz 7253 10 sternal sternal JJ cord-015369-72cjogxz 7253 11 fixation fixation NN cord-015369-72cjogxz 7253 12 without without IN cord-015369-72cjogxz 7253 13 injuring injure VBG cord-015369-72cjogxz 7253 14 the the DT cord-015369-72cjogxz 7253 15 bone bone NN cord-015369-72cjogxz 7253 16 as as IN cord-015369-72cjogxz 7253 17 it -PRON- PRP cord-015369-72cjogxz 7253 18 pulls pull VBZ cord-015369-72cjogxz 7253 19 the the DT cord-015369-72cjogxz 7253 20 two two CD cord-015369-72cjogxz 7253 21 sternum sternum NN cord-015369-72cjogxz 7253 22 halves half NNS cord-015369-72cjogxz 7253 23 together together RB cord-015369-72cjogxz 7253 24 , , , cord-015369-72cjogxz 7253 25 without without IN cord-015369-72cjogxz 7253 26 cutting cut VBG cord-015369-72cjogxz 7253 27 or or CC cord-015369-72cjogxz 7253 28 screwing screw VBG cord-015369-72cjogxz 7253 29 through through IN cord-015369-72cjogxz 7253 30 the the DT cord-015369-72cjogxz 7253 31 bone bone NN cord-015369-72cjogxz 7253 32 , , , cord-015369-72cjogxz 7253 33 thus thus RB cord-015369-72cjogxz 7253 34 preserving preserve VBG cord-015369-72cjogxz 7253 35 the the DT cord-015369-72cjogxz 7253 36 bone bone NN cord-015369-72cjogxz 7253 37 integrity integrity NN cord-015369-72cjogxz 7253 38 . . . cord-015369-72cjogxz 7254 1 Full full JJ cord-015369-72cjogxz 7254 2 sternal sternal JJ cord-015369-72cjogxz 7254 3 closure closure NN cord-015369-72cjogxz 7254 4 is be VBZ cord-015369-72cjogxz 7254 5 achieved achieve VBN cord-015369-72cjogxz 7254 6 in in IN cord-015369-72cjogxz 7254 7 a a DT cord-015369-72cjogxz 7254 8 minimum minimum NN cord-015369-72cjogxz 7254 9 of of IN cord-015369-72cjogxz 7254 10 time time NN cord-015369-72cjogxz 7254 11 in in IN cord-015369-72cjogxz 7254 12 contrast contrast NN cord-015369-72cjogxz 7254 13 to to IN cord-015369-72cjogxz 7254 14 other other JJ cord-015369-72cjogxz 7254 15 rigid rigid JJ cord-015369-72cjogxz 7254 16 fixation fixation NN cord-015369-72cjogxz 7254 17 devices device NNS cord-015369-72cjogxz 7254 18 . . . cord-015369-72cjogxz 7255 1 Through through IN cord-015369-72cjogxz 7255 2 the the DT cord-015369-72cjogxz 7255 3 non non JJ cord-015369-72cjogxz 7255 4 touch touch NN cord-015369-72cjogxz 7255 5 technique technique NN cord-015369-72cjogxz 7255 6 , , , cord-015369-72cjogxz 7255 7 patients patient NNS cord-015369-72cjogxz 7255 8 experience experience VBP cord-015369-72cjogxz 7255 9 less less JJR cord-015369-72cjogxz 7255 10 pain pain NN cord-015369-72cjogxz 7255 11 and and CC cord-015369-72cjogxz 7255 12 can can MD cord-015369-72cjogxz 7255 13 be be VB cord-015369-72cjogxz 7255 14 mobilized mobilize VBN cord-015369-72cjogxz 7255 15 in in IN cord-015369-72cjogxz 7255 16 a a DT cord-015369-72cjogxz 7255 17 shorter short JJR cord-015369-72cjogxz 7255 18 time time NN cord-015369-72cjogxz 7255 19 . . . cord-015369-72cjogxz 7256 1 We -PRON- PRP cord-015369-72cjogxz 7256 2 want want VBP cord-015369-72cjogxz 7256 3 to to TO cord-015369-72cjogxz 7256 4 share share VB cord-015369-72cjogxz 7256 5 our -PRON- PRP$ cord-015369-72cjogxz 7256 6 experiences experience NNS cord-015369-72cjogxz 7256 7 with with IN cord-015369-72cjogxz 7256 8 the the DT cord-015369-72cjogxz 7256 9 application application NN cord-015369-72cjogxz 7256 10 of of IN cord-015369-72cjogxz 7256 11 the the DT cord-015369-72cjogxz 7256 12 Stratos Stratos NNP cord-015369-72cjogxz 7256 13 TM TM NNP cord-015369-72cjogxz 7256 14 System System NNP cord-015369-72cjogxz 7256 15 ( ( -LRB- cord-015369-72cjogxz 7256 16 Strasbourg Strasbourg NNP cord-015369-72cjogxz 7256 17 Thoracic Thoracic NNP cord-015369-72cjogxz 7256 18 Osteosyntheses Osteosyntheses NNP cord-015369-72cjogxz 7256 19 System System NNP cord-015369-72cjogxz 7256 20 ) ) -RRB- cord-015369-72cjogxz 7256 21 for for IN cord-015369-72cjogxz 7256 22 the the DT cord-015369-72cjogxz 7256 23 correction correction NN cord-015369-72cjogxz 7256 24 of of IN cord-015369-72cjogxz 7256 25 chest chest NN cord-015369-72cjogxz 7256 26 wall wall NN cord-015369-72cjogxz 7256 27 deformities deformity NNS cord-015369-72cjogxz 7256 28 and and CC cord-015369-72cjogxz 7256 29 reconstructive reconstructive JJ cord-015369-72cjogxz 7256 30 surgery surgery NN cord-015369-72cjogxz 7256 31 of of IN cord-015369-72cjogxz 7256 32 the the DT cord-015369-72cjogxz 7256 33 chest chest NN cord-015369-72cjogxz 7256 34 wall wall NN cord-015369-72cjogxz 7256 35 after after IN cord-015369-72cjogxz 7256 36 tumor tumor NN cord-015369-72cjogxz 7256 37 removal removal NN cord-015369-72cjogxz 7256 38 . . . cord-015369-72cjogxz 7257 1 This this DT cord-015369-72cjogxz 7257 2 system system NN cord-015369-72cjogxz 7257 3 uses use VBZ cord-015369-72cjogxz 7257 4 a a DT cord-015369-72cjogxz 7257 5 titanium titanium NN cord-015369-72cjogxz 7257 6 implant implant NN cord-015369-72cjogxz 7257 7 consisting consist VBG cord-015369-72cjogxz 7257 8 of of IN cord-015369-72cjogxz 7257 9 two two CD cord-015369-72cjogxz 7257 10 adaptable adaptable JJ cord-015369-72cjogxz 7257 11 rib rib NN cord-015369-72cjogxz 7257 12 clips clip NNS cord-015369-72cjogxz 7257 13 and and CC cord-015369-72cjogxz 7257 14 a a DT cord-015369-72cjogxz 7257 15 length length NN cord-015369-72cjogxz 7257 16 connecting connect VBG cord-015369-72cjogxz 7257 17 bar bar NN cord-015369-72cjogxz 7257 18 . . . cord-015369-72cjogxz 7258 1 We -PRON- PRP cord-015369-72cjogxz 7258 2 will will MD cord-015369-72cjogxz 7258 3 discuss discuss VB cord-015369-72cjogxz 7258 4 one one CD cord-015369-72cjogxz 7258 5 case case NN cord-015369-72cjogxz 7258 6 of of IN cord-015369-72cjogxz 7258 7 a a DT cord-015369-72cjogxz 7258 8 benign benign JJ cord-015369-72cjogxz 7258 9 condition condition NN cord-015369-72cjogxz 7258 10 and and CC cord-015369-72cjogxz 7258 11 three three CD cord-015369-72cjogxz 7258 12 cases case NNS cord-015369-72cjogxz 7258 13 of of IN cord-015369-72cjogxz 7258 14 reconstructive reconstructive JJ cord-015369-72cjogxz 7258 15 surgery surgery NN cord-015369-72cjogxz 7258 16 of of IN cord-015369-72cjogxz 7258 17 the the DT cord-015369-72cjogxz 7258 18 chest chest NN cord-015369-72cjogxz 7258 19 wall wall NN cord-015369-72cjogxz 7258 20 after after IN cord-015369-72cjogxz 7258 21 radical radical JJ cord-015369-72cjogxz 7258 22 resection resection NN cord-015369-72cjogxz 7258 23 of of IN cord-015369-72cjogxz 7258 24 malignant malignant JJ cord-015369-72cjogxz 7258 25 tumors tumor NNS cord-015369-72cjogxz 7258 26 that that WDT cord-015369-72cjogxz 7258 27 were be VBD cord-015369-72cjogxz 7258 28 treated treat VBN cord-015369-72cjogxz 7258 29 with with IN cord-015369-72cjogxz 7258 30 the the DT cord-015369-72cjogxz 7258 31 above above JJ cord-015369-72cjogxz 7258 32 described describe VBN cord-015369-72cjogxz 7258 33 system system NN cord-015369-72cjogxz 7258 34 . . . cord-015369-72cjogxz 7259 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 7259 2 . . . cord-015369-72cjogxz 7260 1 I -PRON- PRP cord-015369-72cjogxz 7260 2 m be VBP cord-015369-72cjogxz 7260 3 Schnitt Schnitt NNP cord-015369-72cjogxz 7260 4 wurden wurden VBD cord-015369-72cjogxz 7260 5 2,11 2,11 CD cord-015369-72cjogxz 7260 6 Venensegmente Venensegmente NNP cord-015369-72cjogxz 7260 7 bevorzugt bevorzugt NNP cord-015369-72cjogxz 7260 8 vom vom NNP cord-015369-72cjogxz 7260 9 Oberschenkel Oberschenkel NNP cord-015369-72cjogxz 7260 10 entnommen entnommen NN cord-015369-72cjogxz 7260 11 . . . cord-015369-72cjogxz 7261 1 Bei Bei NNP cord-015369-72cjogxz 7261 2 gleichzeitiger gleichzeitiger NN cord-015369-72cjogxz 7261 3 Präparation Präparation NNP cord-015369-72cjogxz 7261 4 der der NNP cord-015369-72cjogxz 7261 5 linken linken NNP cord-015369-72cjogxz 7262 1 Arterie Arterie NNP cord-015369-72cjogxz 7262 2 mammaria mammaria NNP cord-015369-72cjogxz 7262 3 tritt tritt NNP cord-015369-72cjogxz 7262 4 durch durch NNP cord-015369-72cjogxz 7262 5 die die VBP cord-015369-72cjogxz 7262 6 endoskopische endoskopische NNP cord-015369-72cjogxz 7262 7 Venenentnahme Venenentnahme NNP cord-015369-72cjogxz 7262 8 kein kein NNP cord-015369-72cjogxz 7262 9 Zeitverlust Zeitverlust NNP cord-015369-72cjogxz 7262 10 auf auf NNP cord-015369-72cjogxz 7262 11 . . . cord-015369-72cjogxz 7263 1 In in IN cord-015369-72cjogxz 7263 2 2 2 CD cord-015369-72cjogxz 7263 3 ( ( -LRB- cord-015369-72cjogxz 7263 4 2,3 2,3 CD cord-015369-72cjogxz 7263 5 % % NN cord-015369-72cjogxz 7263 6 ) ) -RRB- cord-015369-72cjogxz 7264 1 Fällen Fällen NNP cord-015369-72cjogxz 7264 2 kam kam NNP cord-015369-72cjogxz 7264 3 es es XX cord-015369-72cjogxz 7264 4 zu zu NNP cord-015369-72cjogxz 7264 5 einer einer NNP cord-015369-72cjogxz 7264 6 Verletzung Verletzung NNP cord-015369-72cjogxz 7264 7 der der NNP cord-015369-72cjogxz 7264 8 VSM VSM NNP cord-015369-72cjogxz 7264 9 . . . cord-015369-72cjogxz 7265 1 Bei Bei NNP cord-015369-72cjogxz 7265 2 2 2 CD cord-015369-72cjogxz 7265 3 ( ( -LRB- cord-015369-72cjogxz 7265 4 2,3 2,3 CD cord-015369-72cjogxz 7265 5 % % NN cord-015369-72cjogxz 7265 6 ) ) -RRB- cord-015369-72cjogxz 7266 1 Patienten Patienten NNP cord-015369-72cjogxz 7266 2 war war NN cord-015369-72cjogxz 7267 1 eine eine NNP cord-015369-72cjogxz 7267 2 Konversion Konversion NNP cord-015369-72cjogxz 7267 3 aufgrund aufgrund IN cord-015369-72cjogxz 7267 4 einer einer NNP cord-015369-72cjogxz 7267 5 starken starken VBD cord-015369-72cjogxz 7267 6 Blutung Blutung NNP cord-015369-72cjogxz 7267 7 notwendig notwendig NNP cord-015369-72cjogxz 7267 8 und und IN cord-015369-72cjogxz 7267 9 bei bei NNP cord-015369-72cjogxz 7267 10 5 5 CD cord-015369-72cjogxz 7267 11 Eingriffen Eingriffen NNP cord-015369-72cjogxz 7267 12 ( ( -LRB- cord-015369-72cjogxz 7267 13 6 6 CD cord-015369-72cjogxz 7267 14 % % NN cord-015369-72cjogxz 7267 15 ) ) -RRB- cord-015369-72cjogxz 7267 16 zusätzliche zusätzliche NNP cord-015369-72cjogxz 7267 17 Inzisionen Inzisionen NNP cord-015369-72cjogxz 7267 18 . . . cord-015369-72cjogxz 7268 1 Postoperativ Postoperativ NNP cord-015369-72cjogxz 7268 2 beobachteten beobachteten NNP cord-015369-72cjogxz 7268 3 wir wir NNP cord-015369-72cjogxz 7268 4 lediglich lediglich NNP cord-015369-72cjogxz 7269 1 eine eine NNP cord-015369-72cjogxz 7269 2 Wundinfektion Wundinfektion NNP cord-015369-72cjogxz 7269 3 ( ( -LRB- cord-015369-72cjogxz 7269 4 1,1 1,1 CD cord-015369-72cjogxz 7269 5 % % NN cord-015369-72cjogxz 7269 6 ) ) -RRB- cord-015369-72cjogxz 7269 7 , , , cord-015369-72cjogxz 7269 8 welche welche NNP cord-015369-72cjogxz 7269 9 mittels mittels NNP cord-015369-72cjogxz 7269 10 V.A.C. V.A.C. NNP cord-015369-72cjogxz 7269 11 + + CC cord-015369-72cjogxz 7269 12 System System NNP cord-015369-72cjogxz 7269 13 und und IN cord-015369-72cjogxz 7269 14 anschließendem anschließendem NNP cord-015369-72cjogxz 7269 15 sekundärem sekundärem NNP cord-015369-72cjogxz 7269 16 Wundverschluss Wundverschluss NNP cord-015369-72cjogxz 7269 17 behandelt behandelt NNP cord-015369-72cjogxz 7269 18 wurde wurde NNP cord-015369-72cjogxz 7269 19 . . . cord-015369-72cjogxz 7270 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 7270 2 . . . cord-015369-72cjogxz 7271 1 Die die VB cord-015369-72cjogxz 7271 2 endoskopische endoskopische NNP cord-015369-72cjogxz 7271 3 Entnahme Entnahme NNP cord-015369-72cjogxz 7271 4 der der NN cord-015369-72cjogxz 7271 5 VSM VSM NNP cord-015369-72cjogxz 7272 1 ist ist NNP cord-015369-72cjogxz 7272 2 eine eine NNP cord-015369-72cjogxz 7272 3 sichere sichere NNP cord-015369-72cjogxz 7272 4 und und IN cord-015369-72cjogxz 7272 5 mit mit NNP cord-015369-72cjogxz 7272 6 weniger weniger NNP cord-015369-72cjogxz 7272 7 postoperativen postoperativen NNP cord-015369-72cjogxz 7273 1 Komplikationen Komplikationen NNP cord-015369-72cjogxz 7273 2 verbundene verbundene NN cord-015369-72cjogxz 7273 3 Methode Methode NNP cord-015369-72cjogxz 7274 1 i -PRON- PRP cord-015369-72cjogxz 7274 2 m be VBP cord-015369-72cjogxz 7274 3 Vergleich Vergleich NNP cord-015369-72cjogxz 7274 4 zur zur NNP cord-015369-72cjogxz 7274 5 konventionellen konventionellen NNP cord-015369-72cjogxz 7274 6 Präparation Präparation NNP cord-015369-72cjogxz 7274 7 . . . cord-015369-72cjogxz 7275 1 Dies die VBZ cord-015369-72cjogxz 7275 2 sollte sollte NNP cord-015369-72cjogxz 7275 3 einen einen NNP cord-015369-72cjogxz 7275 4 routinemäßigen routinemäßigen NNP cord-015369-72cjogxz 7275 5 Einsatz Einsatz NNP cord-015369-72cjogxz 7275 6 weiter weiter NN cord-015369-72cjogxz 7275 7 fördern fördern NNP cord-015369-72cjogxz 7275 8 . . . cord-015369-72cjogxz 7276 1 Prophylactic prophylactic JJ cord-015369-72cjogxz 7276 2 low low JJ cord-015369-72cjogxz 7276 3 - - HYPH cord-015369-72cjogxz 7276 4 energy energy NN cord-015369-72cjogxz 7276 5 shock shock NN cord-015369-72cjogxz 7276 6 wave wave NN cord-015369-72cjogxz 7276 7 therapy therapy NN cord-015369-72cjogxz 7276 8 improves improve VBZ cord-015369-72cjogxz 7276 9 wound wound VBP cord-015369-72cjogxz 7276 10 healing healing NN cord-015369-72cjogxz 7276 11 after after IN cord-015369-72cjogxz 7276 12 vein vein NN cord-015369-72cjogxz 7276 13 harvesting harvesting NN cord-015369-72cjogxz 7276 14 for for IN cord-015369-72cjogxz 7276 15 coronary coronary JJ cord-015369-72cjogxz 7276 16 artery artery NN cord-015369-72cjogxz 7276 17 bypass bypass NN cord-015369-72cjogxz 7276 18 graft graft NN cord-015369-72cjogxz 7276 19 surgery surgery NN cord-015369-72cjogxz 7276 20 Background background NN cord-015369-72cjogxz 7276 21 . . . cord-015369-72cjogxz 7277 1 Wound wound JJ cord-015369-72cjogxz 7277 2 healing healing NN cord-015369-72cjogxz 7277 3 disorders disorder NNS cord-015369-72cjogxz 7277 4 after after IN cord-015369-72cjogxz 7277 5 vein vein NN cord-015369-72cjogxz 7277 6 harvesting harvesting NN cord-015369-72cjogxz 7277 7 for for IN cord-015369-72cjogxz 7277 8 CABG CABG NNP cord-015369-72cjogxz 7277 9 surgery surgery NN cord-015369-72cjogxz 7277 10 increase increase NN cord-015369-72cjogxz 7277 11 morbidity morbidity NN cord-015369-72cjogxz 7277 12 and and CC cord-015369-72cjogxz 7277 13 lower low JJR cord-015369-72cjogxz 7277 14 patient patient JJ cord-015369-72cjogxz 7277 15 satisfaction satisfaction NN cord-015369-72cjogxz 7277 16 . . . cord-015369-72cjogxz 7278 1 Low low JJ cord-015369-72cjogxz 7278 2 - - HYPH cord-015369-72cjogxz 7278 3 energy energy NN cord-015369-72cjogxz 7278 4 shock shock NN cord-015369-72cjogxz 7278 5 wave wave NN cord-015369-72cjogxz 7278 6 therapy therapy NN cord-015369-72cjogxz 7278 7 ( ( -LRB- cord-015369-72cjogxz 7278 8 SWT SWT NNP cord-015369-72cjogxz 7278 9 ) ) -RRB- cord-015369-72cjogxz 7278 10 reportedly reportedly RB cord-015369-72cjogxz 7278 11 improves improve VBZ cord-015369-72cjogxz 7278 12 healing healing NN cord-015369-72cjogxz 7278 13 of of IN cord-015369-72cjogxz 7278 14 diabetic diabetic JJ cord-015369-72cjogxz 7278 15 and and CC cord-015369-72cjogxz 7278 16 vascular vascular JJ cord-015369-72cjogxz 7278 17 ulcers ulcer NNS cord-015369-72cjogxz 7278 18 by by IN cord-015369-72cjogxz 7278 19 overexpression overexpression NN cord-015369-72cjogxz 7278 20 of of IN cord-015369-72cjogxz 7278 21 vascular vascular JJ cord-015369-72cjogxz 7278 22 endothelial endothelial JJ cord-015369-72cjogxz 7278 23 growth growth NN cord-015369-72cjogxz 7278 24 fractor fractor NN cord-015369-72cjogxz 7278 25 and and CC cord-015369-72cjogxz 7278 26 downregulation downregulation NN cord-015369-72cjogxz 7278 27 of of IN cord-015369-72cjogxz 7278 28 necrosis necrosis NN cord-015369-72cjogxz 7278 29 factor factor NN cord-015369-72cjogxz 7278 30 kappaB. kappaB. NNP cord-015369-72cjogxz 7279 1 In in IN cord-015369-72cjogxz 7279 2 this this DT cord-015369-72cjogxz 7279 3 study study NN cord-015369-72cjogxz 7279 4 , , , cord-015369-72cjogxz 7279 5 we -PRON- PRP cord-015369-72cjogxz 7279 6 investigate investigate VBP cord-015369-72cjogxz 7279 7 whether whether IN cord-015369-72cjogxz 7279 8 prophylactic prophylactic JJ cord-015369-72cjogxz 7279 9 low low JJ cord-015369-72cjogxz 7279 10 - - HYPH cord-015369-72cjogxz 7279 11 energy energy NN cord-015369-72cjogxz 7279 12 SWT SWT NNP cord-015369-72cjogxz 7279 13 improves improve VBZ cord-015369-72cjogxz 7279 14 wound wind VBN cord-015369-72cjogxz 7279 15 healing healing NN cord-015369-72cjogxz 7279 16 after after IN cord-015369-72cjogxz 7279 17 vein vein NN cord-015369-72cjogxz 7279 18 harvesting harvesting NN cord-015369-72cjogxz 7279 19 for for IN cord-015369-72cjogxz 7279 20 coronary coronary JJ cord-015369-72cjogxz 7279 21 artery artery NN cord-015369-72cjogxz 7279 22 bypass bypass NN cord-015369-72cjogxz 7279 23 graft graft NN cord-015369-72cjogxz 7279 24 surgery surgery NN cord-015369-72cjogxz 7279 25 . . . cord-015369-72cjogxz 7280 1 Methods method NNS cord-015369-72cjogxz 7280 2 . . . cord-015369-72cjogxz 7281 1 One one CD cord-015369-72cjogxz 7281 2 hundred hundred CD cord-015369-72cjogxz 7281 3 consecutive consecutive JJ cord-015369-72cjogxz 7281 4 patients patient NNS cord-015369-72cjogxz 7281 5 undergoing undergo VBG cord-015369-72cjogxz 7281 6 CABG CABG NNP cord-015369-72cjogxz 7281 7 surgery surgery NN cord-015369-72cjogxz 7281 8 were be VBD cord-015369-72cjogxz 7281 9 randomly randomly RB cord-015369-72cjogxz 7281 10 assigned assign VBN cord-015369-72cjogxz 7281 11 to to IN cord-015369-72cjogxz 7281 12 either either CC cord-015369-72cjogxz 7281 13 prophylactic prophylactic JJ cord-015369-72cjogxz 7281 14 low low JJ cord-015369-72cjogxz 7281 15 - - HYPH cord-015369-72cjogxz 7281 16 energy energy NN cord-015369-72cjogxz 7281 17 SWT SWT NNP cord-015369-72cjogxz 7281 18 ( ( -LRB- cord-015369-72cjogxz 7281 19 n n NN cord-015369-72cjogxz 7281 20 ¼ ¼ NNP cord-015369-72cjogxz 7281 21 50 50 CD cord-015369-72cjogxz 7281 22 ) ) -RRB- cord-015369-72cjogxz 7281 23 or or CC cord-015369-72cjogxz 7281 24 control control NN cord-015369-72cjogxz 7281 25 ( ( -LRB- cord-015369-72cjogxz 7281 26 n n NN cord-015369-72cjogxz 7281 27 ¼ ¼ NNP cord-015369-72cjogxz 7281 28 50 50 CD cord-015369-72cjogxz 7281 29 ) ) -RRB- cord-015369-72cjogxz 7281 30 . . . cord-015369-72cjogxz 7282 1 Low low JJ cord-015369-72cjogxz 7282 2 - - HYPH cord-015369-72cjogxz 7282 3 energy energy NN cord-015369-72cjogxz 7282 4 SWT SWT NNP cord-015369-72cjogxz 7282 5 was be VBD cord-015369-72cjogxz 7282 6 applied apply VBN cord-015369-72cjogxz 7282 7 to to IN cord-015369-72cjogxz 7282 8 the the DT cord-015369-72cjogxz 7282 9 site site NN cord-015369-72cjogxz 7282 10 of of IN cord-015369-72cjogxz 7282 11 vein vein NN cord-015369-72cjogxz 7282 12 harvesting harvesting NN cord-015369-72cjogxz 7282 13 after after IN cord-015369-72cjogxz 7282 14 wound wound NN cord-015369-72cjogxz 7282 15 closure closure NN cord-015369-72cjogxz 7282 16 under under IN cord-015369-72cjogxz 7282 17 sterile sterile JJ cord-015369-72cjogxz 7282 18 conditions condition NNS cord-015369-72cjogxz 7282 19 using use VBG cord-015369-72cjogxz 7282 20 a a DT cord-015369-72cjogxz 7282 21 commercially commercially RB cord-015369-72cjogxz 7282 22 available available JJ cord-015369-72cjogxz 7282 23 SWT SWT NNP cord-015369-72cjogxz 7282 24 system system NN cord-015369-72cjogxz 7282 25 ( ( -LRB- cord-015369-72cjogxz 7282 26 Dermagold Dermagold NNP cord-015369-72cjogxz 7282 27 ; ; : cord-015369-72cjogxz 7282 28 Tissue tissue NN cord-015369-72cjogxz 7282 29 Regeneration regeneration NN cord-015369-72cjogxz 7282 30 Technologies Technologies NNPS cord-015369-72cjogxz 7282 31 , , , cord-015369-72cjogxz 7282 32 Woodstock Woodstock NNP cord-015369-72cjogxz 7282 33 , , , cord-015369-72cjogxz 7282 34 GA GA NNP cord-015369-72cjogxz 7282 35 ) ) -RRB- cord-015369-72cjogxz 7282 36 . . . cord-015369-72cjogxz 7283 1 A a DT cord-015369-72cjogxz 7283 2 total total NN cord-015369-72cjogxz 7283 3 of of IN cord-015369-72cjogxz 7283 4 25 25 CD cord-015369-72cjogxz 7283 5 impulses impulse NNS cord-015369-72cjogxz 7283 6 ( ( -LRB- cord-015369-72cjogxz 7283 7 0.1 0.1 CD cord-015369-72cjogxz 7283 8 mJ mJ NNP cord-015369-72cjogxz 7283 9 / / SYM cord-015369-72cjogxz 7283 10 mm(2 mm(2 NNP cord-015369-72cjogxz 7283 11 ) ) -RRB- cord-015369-72cjogxz 7283 12 ; ; : cord-015369-72cjogxz 7283 13 5 5 CD cord-015369-72cjogxz 7283 14 Hz Hz NNP cord-015369-72cjogxz 7283 15 ) ) -RRB- cord-015369-72cjogxz 7283 16 were be VBD cord-015369-72cjogxz 7283 17 applied apply VBN cord-015369-72cjogxz 7283 18 per per IN cord-015369-72cjogxz 7283 19 centimeter centimeter NN cord-015369-72cjogxz 7283 20 wound wound NN cord-015369-72cjogxz 7283 21 length length NN cord-015369-72cjogxz 7283 22 . . . cord-015369-72cjogxz 7284 1 Wound wound JJ cord-015369-72cjogxz 7284 2 healing healing NN cord-015369-72cjogxz 7284 3 was be VBD cord-015369-72cjogxz 7284 4 evaluated evaluate VBN cord-015369-72cjogxz 7284 5 and and CC cord-015369-72cjogxz 7284 6 quantified quantify VBN cord-015369-72cjogxz 7284 7 using use VBG cord-015369-72cjogxz 7284 8 the the DT cord-015369-72cjogxz 7284 9 ASEPSIS ASEPSIS NNP cord-015369-72cjogxz 7284 10 score score NN cord-015369-72cjogxz 7284 11 . . . cord-015369-72cjogxz 7285 1 Results result NNS cord-015369-72cjogxz 7285 2 . . . cord-015369-72cjogxz 7286 1 Patient patient JJ cord-015369-72cjogxz 7286 2 characteristics characteristic NNS cord-015369-72cjogxz 7286 3 and and CC cord-015369-72cjogxz 7286 4 operative operative NN cord-015369-72cjogxz 7286 5 data datum NNS cord-015369-72cjogxz 7286 6 including include VBG cord-015369-72cjogxz 7286 7 wound wound JJ cord-015369-72cjogxz 7286 8 length length NN cord-015369-72cjogxz 7286 9 ( ( -LRB- cord-015369-72cjogxz 7286 10 SWT SWT NNP cord-015369-72cjogxz 7286 11 39 39 CD cord-015369-72cjogxz 7286 12 AE AE NNP cord-015369-72cjogxz 7286 13 13 13 CD cord-015369-72cjogxz 7286 14 cm cm NNS cord-015369-72cjogxz 7286 15 versus versus IN cord-015369-72cjogxz 7286 16 control control NN cord-015369-72cjogxz 7286 17 37 37 CD cord-015369-72cjogxz 7286 18 AE AE NNP cord-015369-72cjogxz 7286 19 11 11 CD cord-015369-72cjogxz 7286 20 cm cm NNS cord-015369-72cjogxz 7286 21 , , , cord-015369-72cjogxz 7286 22 p p NN cord-015369-72cjogxz 7286 23 ¼ ¼ NNP cord-015369-72cjogxz 7286 24 0.342 0.342 CD cord-015369-72cjogxz 7286 25 ) ) -RRB- cord-015369-72cjogxz 7286 26 were be VBD cord-015369-72cjogxz 7286 27 comparable comparable JJ cord-015369-72cjogxz 7286 28 between between IN cord-015369-72cjogxz 7286 29 the the DT cord-015369-72cjogxz 7286 30 two two CD cord-015369-72cjogxz 7286 31 groups group NNS cord-015369-72cjogxz 7286 32 . . . cord-015369-72cjogxz 7287 1 We -PRON- PRP cord-015369-72cjogxz 7287 2 observed observe VBD cord-015369-72cjogxz 7287 3 lower low JJR cord-015369-72cjogxz 7287 4 ASEPSIS ASEPSIS NNP cord-015369-72cjogxz 7287 5 scores score NNS cord-015369-72cjogxz 7287 6 indicating indicate VBG cord-015369-72cjogxz 7287 7 improved improve VBN cord-015369-72cjogxz 7287 8 wound wound NN cord-015369-72cjogxz 7287 9 healing healing NN cord-015369-72cjogxz 7287 10 in in IN cord-015369-72cjogxz 7287 11 the the DT cord-015369-72cjogxz 7287 12 SWT SWT NNP cord-015369-72cjogxz 7287 13 group group NN cord-015369-72cjogxz 7287 14 ( ( -LRB- cord-015369-72cjogxz 7287 15 4.4 4.4 CD cord-015369-72cjogxz 7287 16 AE AE NNP cord-015369-72cjogxz 7287 17 5.3 5.3 CD cord-015369-72cjogxz 7287 18 ) ) -RRB- cord-015369-72cjogxz 7287 19 compared compare VBN cord-015369-72cjogxz 7287 20 with with IN cord-015369-72cjogxz 7287 21 the the DT cord-015369-72cjogxz 7287 22 control control NN cord-015369-72cjogxz 7287 23 group group NN cord-015369-72cjogxz 7287 24 ( ( -LRB- cord-015369-72cjogxz 7287 25 11.6 11.6 CD cord-015369-72cjogxz 7287 26 AE AE NNP cord-015369-72cjogxz 7287 27 8.3 8.3 CD cord-015369-72cjogxz 7287 28 , , , cord-015369-72cjogxz 7287 29 p p NN cord-015369-72cjogxz 7287 30 ¼ ¼ CD cord-015369-72cjogxz 7287 31 0.0001 0.0001 CD cord-015369-72cjogxz 7287 32 ) ) -RRB- cord-015369-72cjogxz 7287 33 . . . cord-015369-72cjogxz 7288 1 Interestingly interestingly RB cord-015369-72cjogxz 7288 2 , , , cord-015369-72cjogxz 7288 3 we -PRON- PRP cord-015369-72cjogxz 7288 4 observed observe VBD cord-015369-72cjogxz 7288 5 a a DT cord-015369-72cjogxz 7288 6 higher high JJR cord-015369-72cjogxz 7288 7 incidence incidence NN cord-015369-72cjogxz 7288 8 of of IN cord-015369-72cjogxz 7288 9 wound wound JJ cord-015369-72cjogxz 7288 10 healing healing NN cord-015369-72cjogxz 7288 11 disorders disorder NNS cord-015369-72cjogxz 7288 12 necessitating necessitate VBG cord-015369-72cjogxz 7288 13 antibiotic antibiotic JJ cord-015369-72cjogxz 7288 14 treatment treatment NN cord-015369-72cjogxz 7288 15 in in IN cord-015369-72cjogxz 7288 16 the the DT cord-015369-72cjogxz 7288 17 control control NN cord-015369-72cjogxz 7288 18 group group NN cord-015369-72cjogxz 7288 19 ( ( -LRB- cord-015369-72cjogxz 7288 20 22 22 CD cord-015369-72cjogxz 7288 21 % % NN cord-015369-72cjogxz 7288 22 ) ) -RRB- cord-015369-72cjogxz 7288 23 as as IN cord-015369-72cjogxz 7288 24 compared compare VBN cord-015369-72cjogxz 7288 25 with with IN cord-015369-72cjogxz 7288 26 the the DT cord-015369-72cjogxz 7288 27 SWT SWT NNP cord-015369-72cjogxz 7288 28 group group NN cord-015369-72cjogxz 7288 29 ( ( -LRB- cord-015369-72cjogxz 7288 30 4 4 CD cord-015369-72cjogxz 7288 31 % % NN cord-015369-72cjogxz 7288 32 , , , cord-015369-72cjogxz 7288 33 p p NN cord-015369-72cjogxz 7288 34 ¼ ¼ NNP cord-015369-72cjogxz 7288 35 0.015).Conclusions 0.015).conclusion NNS cord-015369-72cjogxz 7288 36 . . . cord-015369-72cjogxz 7289 1 As as IN cord-015369-72cjogxz 7289 2 shown show VBN cord-015369-72cjogxz 7289 3 in in IN cord-015369-72cjogxz 7289 4 this this DT cord-015369-72cjogxz 7289 5 prospective prospective JJ cord-015369-72cjogxz 7289 6 randomized randomized JJ cord-015369-72cjogxz 7289 7 study study NN cord-015369-72cjogxz 7289 8 , , , cord-015369-72cjogxz 7289 9 prophylactic prophylactic JJ cord-015369-72cjogxz 7289 10 application application NN cord-015369-72cjogxz 7289 11 of of IN cord-015369-72cjogxz 7289 12 low low JJ cord-015369-72cjogxz 7289 13 - - HYPH cord-015369-72cjogxz 7289 14 energy energy NN cord-015369-72cjogxz 7289 15 SWT SWT NNP cord-015369-72cjogxz 7289 16 improves improve VBZ cord-015369-72cjogxz 7289 17 wound wind VBN cord-015369-72cjogxz 7289 18 healing healing NN cord-015369-72cjogxz 7289 19 after after IN cord-015369-72cjogxz 7289 20 vein vein NN cord-015369-72cjogxz 7289 21 harvesting harvesting NN cord-015369-72cjogxz 7289 22 for for IN cord-015369-72cjogxz 7289 23 coronary coronary JJ cord-015369-72cjogxz 7289 24 artery artery NN cord-015369-72cjogxz 7289 25 bypass bypass NN cord-015369-72cjogxz 7289 26 graft graft NN cord-015369-72cjogxz 7289 27 surgery surgery NN cord-015369-72cjogxz 7289 28 . . . cord-015369-72cjogxz 7290 1 Myocardial myocardial JJ cord-015369-72cjogxz 7290 2 regeneration regeneration NN cord-015369-72cjogxz 7290 3 by by IN cord-015369-72cjogxz 7290 4 shock shock NN cord-015369-72cjogxz 7290 5 wave wave NN cord-015369-72cjogxz 7290 6 therapyan therapyan NNP cord-015369-72cjogxz 7290 7 in in IN cord-015369-72cjogxz 7290 8 - - HYPH cord-015369-72cjogxz 7290 9 vitro vitro FW cord-015369-72cjogxz 7290 10 examination examination NN cord-015369-72cjogxz 7290 11 Background background NN cord-015369-72cjogxz 7290 12 . . . cord-015369-72cjogxz 7291 1 Inflammation inflammation NN cord-015369-72cjogxz 7291 2 and and CC cord-015369-72cjogxz 7291 3 thrombogenicity thrombogenicity NN cord-015369-72cjogxz 7291 4 are be VBP cord-015369-72cjogxz 7291 5 important important JJ cord-015369-72cjogxz 7291 6 issues issue NNS cord-015369-72cjogxz 7291 7 in in IN cord-015369-72cjogxz 7291 8 cardiovascular cardiovascular JJ cord-015369-72cjogxz 7291 9 tissue tissue NN cord-015369-72cjogxz 7291 10 engineering engineering NN cord-015369-72cjogxz 7291 11 . . . cord-015369-72cjogxz 7292 1 This this DT cord-015369-72cjogxz 7292 2 in in IN cord-015369-72cjogxz 7292 3 - - HYPH cord-015369-72cjogxz 7292 4 vitro vitro FW cord-015369-72cjogxz 7292 5 study study NN cord-015369-72cjogxz 7292 6 was be VBD cord-015369-72cjogxz 7292 7 designed design VBN cord-015369-72cjogxz 7292 8 to to TO cord-015369-72cjogxz 7292 9 investigate investigate VB cord-015369-72cjogxz 7292 10 the the DT cord-015369-72cjogxz 7292 11 influence influence NN cord-015369-72cjogxz 7292 12 of of IN cord-015369-72cjogxz 7292 13 platelet platelet NN cord-015369-72cjogxz 7292 14 alpha alpha NN cord-015369-72cjogxz 7292 15 granule granule NN cord-015369-72cjogxz 7292 16 release release NN cord-015369-72cjogxz 7292 17 on on IN cord-015369-72cjogxz 7292 18 polymorphonuclear polymorphonuclear JJ cord-015369-72cjogxz 7292 19 leukocytes leukocyte NNS cord-015369-72cjogxz 7292 20 ( ( -LRB- cord-015369-72cjogxz 7292 21 PMN pmn NN cord-015369-72cjogxz 7292 22 ) ) -RRB- cord-015369-72cjogxz 7292 23 adhesion adhesion NN cord-015369-72cjogxz 7292 24 and and CC cord-015369-72cjogxz 7292 25 activation activation NN cord-015369-72cjogxz 7292 26 on on IN cord-015369-72cjogxz 7292 27 the the DT cord-015369-72cjogxz 7292 28 decellularized decellularized JJ cord-015369-72cjogxz 7292 29 porcine porcine JJ cord-015369-72cjogxz 7292 30 matrix matrix NN cord-015369-72cjogxz 7292 31 . . . cord-015369-72cjogxz 7293 1 Methods method NNS cord-015369-72cjogxz 7293 2 . . . cord-015369-72cjogxz 7294 1 Cryostat cryostat JJ cord-015369-72cjogxz 7294 2 sections section NNS cord-015369-72cjogxz 7294 3 of of IN cord-015369-72cjogxz 7294 4 decellularized decellularized JJ cord-015369-72cjogxz 7294 5 porcine porcine JJ cord-015369-72cjogxz 7294 6 heart heart NN cord-015369-72cjogxz 7294 7 valves valve NNS cord-015369-72cjogxz 7294 8 were be VBD cord-015369-72cjogxz 7294 9 sequentially sequentially RB cord-015369-72cjogxz 7294 10 incubated incubate VBN cord-015369-72cjogxz 7294 11 with with IN cord-015369-72cjogxz 7294 12 platelet platelet NN cord-015369-72cjogxz 7294 13 - - HYPH cord-015369-72cjogxz 7294 14 rich rich JJ cord-015369-72cjogxz 7294 15 plasma plasma NN cord-015369-72cjogxz 7294 16 ( ( -LRB- cord-015369-72cjogxz 7294 17 PRP prp NN cord-015369-72cjogxz 7294 18 ) ) -RRB- cord-015369-72cjogxz 7294 19 and and CC cord-015369-72cjogxz 7294 20 isolated isolate VBN cord-015369-72cjogxz 7294 21 , , , cord-015369-72cjogxz 7294 22 autologous autologous JJ cord-015369-72cjogxz 7294 23 PMN PMN NNP cord-015369-72cjogxz 7294 24 . . . cord-015369-72cjogxz 7295 1 To to TO cord-015369-72cjogxz 7295 2 block block VB cord-015369-72cjogxz 7295 3 -granule -granule JJ cord-015369-72cjogxz 7295 4 release release NN cord-015369-72cjogxz 7295 5 platelets platelet NNS cord-015369-72cjogxz 7295 6 were be VBD cord-015369-72cjogxz 7295 7 pre pre JJ cord-015369-72cjogxz 7295 8 - - VBN cord-015369-72cjogxz 7295 9 incubated incubate VBN cord-015369-72cjogxz 7295 10 with with IN cord-015369-72cjogxz 7295 11 either either CC cord-015369-72cjogxz 7295 12 Cytochalasin Cytochalasin NNP cord-015369-72cjogxz 7295 13 D D NNP cord-015369-72cjogxz 7295 14 ( ( -LRB- cord-015369-72cjogxz 7295 15 CytD CytD NNP cord-015369-72cjogxz 7295 16 ) ) -RRB- cord-015369-72cjogxz 7295 17 or or CC cord-015369-72cjogxz 7295 18 iso iso NN cord-015369-72cjogxz 7295 19 - - HYPH cord-015369-72cjogxz 7295 20 butyl butyl NN cord-015369-72cjogxz 7295 21 - - HYPH cord-015369-72cjogxz 7295 22 methyl methyl NN cord-015369-72cjogxz 7295 23 - - HYPH cord-015369-72cjogxz 7295 24 xanthine xanthine NN cord-015369-72cjogxz 7295 25 ( ( -LRB- cord-015369-72cjogxz 7295 26 IBMX IBMX NNP cord-015369-72cjogxz 7295 27 ) ) -RRB- cord-015369-72cjogxz 7295 28 . . . cord-015369-72cjogxz 7296 1 To to TO cord-015369-72cjogxz 7296 2 investigate investigate VB cord-015369-72cjogxz 7296 3 the the DT cord-015369-72cjogxz 7296 4 involvement involvement NN cord-015369-72cjogxz 7296 5 of of IN cord-015369-72cjogxz 7296 6 the the DT cord-015369-72cjogxz 7296 7 complement complement NN cord-015369-72cjogxz 7296 8 system system NN cord-015369-72cjogxz 7296 9 , , , cord-015369-72cjogxz 7296 10 specimens specimen NNS cord-015369-72cjogxz 7296 11 were be VBD cord-015369-72cjogxz 7296 12 exposed expose VBN cord-015369-72cjogxz 7296 13 to to IN cord-015369-72cjogxz 7296 14 PRP PRP NNP cord-015369-72cjogxz 7296 15 that that WDT cord-015369-72cjogxz 7296 16 had have VBD cord-015369-72cjogxz 7296 17 been be VBN cord-015369-72cjogxz 7296 18 pre pre VBN cord-015369-72cjogxz 7296 19 - - VBN cord-015369-72cjogxz 7296 20 incubated incubate VBN cord-015369-72cjogxz 7296 21 with with IN cord-015369-72cjogxz 7296 22 10 10 CD cord-015369-72cjogxz 7296 23 mM mm CD cord-015369-72cjogxz 7296 24 EDTA edta NN cord-015369-72cjogxz 7296 25 . . . cord-015369-72cjogxz 7297 1 At at IN cord-015369-72cjogxz 7297 2 the the DT cord-015369-72cjogxz 7297 3 end end NN cord-015369-72cjogxz 7297 4 of of IN cord-015369-72cjogxz 7297 5 the the DT cord-015369-72cjogxz 7297 6 incubations incubation NNS cord-015369-72cjogxz 7297 7 , , , cord-015369-72cjogxz 7297 8 specimens specimen NNS cord-015369-72cjogxz 7297 9 were be VBD cord-015369-72cjogxz 7297 10 fluorescently fluorescently RB cord-015369-72cjogxz 7297 11 stained stain VBN cord-015369-72cjogxz 7297 12 for for IN cord-015369-72cjogxz 7297 13 CD CD NNP cord-015369-72cjogxz 7297 14 41 41 CD cord-015369-72cjogxz 7297 15 , , , cord-015369-72cjogxz 7297 16 thrombospondin-1 thrombospondin-1 NNP cord-015369-72cjogxz 7297 17 ( ( -LRB- cord-015369-72cjogxz 7297 18 TSP-1 TSP-1 NNP cord-015369-72cjogxz 7297 19 ) ) -RRB- cord-015369-72cjogxz 7297 20 , , , cord-015369-72cjogxz 7297 21 CD45 CD45 NNP cord-015369-72cjogxz 7297 22 , , , cord-015369-72cjogxz 7297 23 CD11b CD11b NNPS cord-015369-72cjogxz 7297 24 , , , cord-015369-72cjogxz 7297 25 and and CC cord-015369-72cjogxz 7297 26 the the DT cord-015369-72cjogxz 7297 27 complement complement NN cord-015369-72cjogxz 7297 28 factor factor NN cord-015369-72cjogxz 7297 29 iC3b ic3b RB cord-015369-72cjogxz 7297 30 . . . cord-015369-72cjogxz 7298 1 Results result NNS cord-015369-72cjogxz 7298 2 . . . cord-015369-72cjogxz 7299 1 Laser laser NN cord-015369-72cjogxz 7299 2 scanning scanning NN cord-015369-72cjogxz 7299 3 microscopy microscopy NNS cord-015369-72cjogxz 7299 4 revealed reveal VBD cord-015369-72cjogxz 7299 5 the the DT cord-015369-72cjogxz 7299 6 binding binding NN cord-015369-72cjogxz 7299 7 of of IN cord-015369-72cjogxz 7299 8 multiple multiple JJ cord-015369-72cjogxz 7299 9 platelet platelet NN cord-015369-72cjogxz 7299 10 aggregates aggregate NNS cord-015369-72cjogxz 7299 11 to to IN cord-015369-72cjogxz 7299 12 the the DT cord-015369-72cjogxz 7299 13 decellularized decellularized JJ cord-015369-72cjogxz 7299 14 porcine porcine JJ cord-015369-72cjogxz 7299 15 tissue tissue NN cord-015369-72cjogxz 7299 16 surface surface NN cord-015369-72cjogxz 7299 17 . . . cord-015369-72cjogxz 7300 1 Platelet platelet NN cord-015369-72cjogxz 7300 2 adhesion adhesion NN cord-015369-72cjogxz 7300 3 was be VBD cord-015369-72cjogxz 7300 4 associated associate VBN cord-015369-72cjogxz 7300 5 with with IN cord-015369-72cjogxz 7300 6 up up RB cord-015369-72cjogxz 7300 7 regulated regulated JJ cord-015369-72cjogxz 7300 8 expression expression NN cord-015369-72cjogxz 7300 9 of of IN cord-015369-72cjogxz 7300 10 TSP-1 TSP-1 NNP cord-015369-72cjogxz 7300 11 . . . cord-015369-72cjogxz 7301 1 Pre pre JJ cord-015369-72cjogxz 7301 2 - - JJ cord-015369-72cjogxz 7301 3 treatment treatment NN cord-015369-72cjogxz 7301 4 of of IN cord-015369-72cjogxz 7301 5 tissue tissue NN cord-015369-72cjogxz 7301 6 specimens specimen NNS cord-015369-72cjogxz 7301 7 with with IN cord-015369-72cjogxz 7301 8 PRP PRP NNP cord-015369-72cjogxz 7301 9 induced induce VBD cord-015369-72cjogxz 7301 10 a a DT cord-015369-72cjogxz 7301 11 strongly strongly RB cord-015369-72cjogxz 7301 12 enhanced enhance VBN cord-015369-72cjogxz 7301 13 binding binding NN cord-015369-72cjogxz 7301 14 and and CC cord-015369-72cjogxz 7301 15 activation activation NN cord-015369-72cjogxz 7301 16 of of IN cord-015369-72cjogxz 7301 17 subsequently subsequently RB cord-015369-72cjogxz 7301 18 added add VBN cord-015369-72cjogxz 7301 19 PMN PMN NNP cord-015369-72cjogxz 7301 20 . . . cord-015369-72cjogxz 7302 1 Inhibition inhibition NN cord-015369-72cjogxz 7302 2 of of IN cord-015369-72cjogxz 7302 3 platelet platelet NN cord-015369-72cjogxz 7303 1 -granule -granule JJ cord-015369-72cjogxz 7303 2 release release NN cord-015369-72cjogxz 7303 3 by by IN cord-015369-72cjogxz 7303 4 either either DT cord-015369-72cjogxz 7303 5 CytD CytD NNP cord-015369-72cjogxz 7303 6 or or CC cord-015369-72cjogxz 7303 7 IBMX IBMX NNP cord-015369-72cjogxz 7303 8 markedly markedly RB cord-015369-72cjogxz 7303 9 reduced reduce VBD cord-015369-72cjogxz 7303 10 the the DT cord-015369-72cjogxz 7303 11 secretion secretion NN cord-015369-72cjogxz 7303 12 of of IN cord-015369-72cjogxz 7303 13 TSP-1 TSP-1 NNP cord-015369-72cjogxz 7303 14 correlating correlate VBG cord-015369-72cjogxz 7303 15 with with IN cord-015369-72cjogxz 7303 16 a a DT cord-015369-72cjogxz 7303 17 decreased decrease VBN cord-015369-72cjogxz 7303 18 PMN PMN NNP cord-015369-72cjogxz 7303 19 adhesion adhesion NN cord-015369-72cjogxz 7303 20 and and CC cord-015369-72cjogxz 7303 21 CD11b CD11b NNPS cord-015369-72cjogxz 7303 22 expression expression NN cord-015369-72cjogxz 7303 23 . . . cord-015369-72cjogxz 7304 1 Although although IN cord-015369-72cjogxz 7304 2 inhibition inhibition NN cord-015369-72cjogxz 7304 3 of of IN cord-015369-72cjogxz 7304 4 complement complement JJ cord-015369-72cjogxz 7304 5 activation activation NN cord-015369-72cjogxz 7304 6 by by IN cord-015369-72cjogxz 7304 7 addition addition NN cord-015369-72cjogxz 7304 8 of of IN cord-015369-72cjogxz 7304 9 EDTA EDTA NNP cord-015369-72cjogxz 7304 10 to to IN cord-015369-72cjogxz 7304 11 PRP PRP NNP cord-015369-72cjogxz 7304 12 inhibited inhibit VBD cord-015369-72cjogxz 7304 13 iC3b ic3b JJ cord-015369-72cjogxz 7304 14 deposition deposition NN cord-015369-72cjogxz 7304 15 , , , cord-015369-72cjogxz 7304 16 it -PRON- PRP cord-015369-72cjogxz 7304 17 failed fail VBD cord-015369-72cjogxz 7304 18 to to TO cord-015369-72cjogxz 7304 19 prevent prevent VB cord-015369-72cjogxz 7304 20 PMN pmn NN cord-015369-72cjogxz 7304 21 binding binding NN cord-015369-72cjogxz 7304 22 . . . cord-015369-72cjogxz 7305 1 Conclusions conclusion NNS cord-015369-72cjogxz 7305 2 . . . cord-015369-72cjogxz 7306 1 The the DT cord-015369-72cjogxz 7306 2 decellularized decellularized JJ cord-015369-72cjogxz 7306 3 porcine porcine JJ cord-015369-72cjogxz 7306 4 heart heart NN cord-015369-72cjogxz 7306 5 valve valve NN cord-015369-72cjogxz 7306 6 matrix matrix NN cord-015369-72cjogxz 7306 7 represents represent VBZ cord-015369-72cjogxz 7306 8 a a DT cord-015369-72cjogxz 7306 9 high high JJ cord-015369-72cjogxz 7306 10 thrombogenic thrombogenic JJ cord-015369-72cjogxz 7306 11 surface surface NN cord-015369-72cjogxz 7306 12 . . . cord-015369-72cjogxz 7307 1 Activated activate VBN cord-015369-72cjogxz 7307 2 platelets platelet NNS cord-015369-72cjogxz 7307 3 induce induce VBP cord-015369-72cjogxz 7307 4 subsequently subsequently RB cord-015369-72cjogxz 7307 5 PMN PMN NNP cord-015369-72cjogxz 7307 6 adhesion adhesion NN cord-015369-72cjogxz 7307 7 and and CC cord-015369-72cjogxz 7307 8 activation activation NN cord-015369-72cjogxz 7307 9 . . . cord-015369-72cjogxz 7308 1 The the DT cord-015369-72cjogxz 7308 2 platelet platelet NN cord-015369-72cjogxz 7308 3 / / SYM cord-015369-72cjogxz 7308 4 PMN PMN NNP cord-015369-72cjogxz 7308 5 interaction interaction NN cord-015369-72cjogxz 7308 6 seems seem VBZ cord-015369-72cjogxz 7308 7 therefore therefore RB cord-015369-72cjogxz 7308 8 to to TO cord-015369-72cjogxz 7308 9 play play VB cord-015369-72cjogxz 7308 10 a a DT cord-015369-72cjogxz 7308 11 key key JJ cord-015369-72cjogxz 7308 12 role role NN cord-015369-72cjogxz 7308 13 in in IN cord-015369-72cjogxz 7308 14 the the DT cord-015369-72cjogxz 7308 15 early early JJ cord-015369-72cjogxz 7308 16 , , , cord-015369-72cjogxz 7308 17 non non JJ cord-015369-72cjogxz 7308 18 - - JJ cord-015369-72cjogxz 7308 19 specific specific JJ cord-015369-72cjogxz 7308 20 inflammatory inflammatory JJ cord-015369-72cjogxz 7308 21 response response NN cord-015369-72cjogxz 7308 22 towards towards IN cord-015369-72cjogxz 7308 23 the the DT cord-015369-72cjogxz 7308 24 decellularized decellularized NNP cord-015369-72cjogxz 7308 25 xenogenic xenogenic NNP cord-015369-72cjogxz 7308 26 matrix matrix NNP cord-015369-72cjogxz 7308 27 independent independent NNP cord-015369-72cjogxz 7308 28 from from IN cord-015369-72cjogxz 7308 29 complement complement JJ cord-015369-72cjogxz 7308 30 activation activation NN cord-015369-72cjogxz 7308 31 . . . cord-015369-72cjogxz 7309 1 Acute acute JJ cord-015369-72cjogxz 7309 2 cellular cellular JJ cord-015369-72cjogxz 7309 3 allograft allograft NN cord-015369-72cjogxz 7309 4 rejection rejection NN cord-015369-72cjogxz 7309 5 ( ( -LRB- cord-015369-72cjogxz 7309 6 ACR ACR NNP cord-015369-72cjogxz 7309 7 ) ) -RRB- cord-015369-72cjogxz 7309 8 remains remain VBZ cord-015369-72cjogxz 7309 9 a a DT cord-015369-72cjogxz 7309 10 significant significant JJ cord-015369-72cjogxz 7309 11 problem problem NN cord-015369-72cjogxz 7309 12 in in IN cord-015369-72cjogxz 7309 13 cardiac cardiac JJ cord-015369-72cjogxz 7309 14 transplantation transplantation NN cord-015369-72cjogxz 7309 15 . . . cord-015369-72cjogxz 7310 1 Calreticulin Calreticulin NNP cord-015369-72cjogxz 7310 2 ( ( -LRB- cord-015369-72cjogxz 7310 3 CRT CRT NNP cord-015369-72cjogxz 7310 4 ) ) -RRB- cord-015369-72cjogxz 7310 5 is be VBZ cord-015369-72cjogxz 7310 6 a a DT cord-015369-72cjogxz 7310 7 Ca Ca NNP cord-015369-72cjogxz 7310 8 2þ 2þ NNS cord-015369-72cjogxz 7310 9 binding bind VBG cord-015369-72cjogxz 7310 10 chaperone chaperone NN cord-015369-72cjogxz 7310 11 suppressing suppress VBG cord-015369-72cjogxz 7310 12 activity activity NN cord-015369-72cjogxz 7310 13 of of IN cord-015369-72cjogxz 7310 14 the the DT cord-015369-72cjogxz 7310 15 sarcoplasmic sarcoplasmic NN cord-015369-72cjogxz 7310 16 / / SYM cord-015369-72cjogxz 7310 17 endoplasmic endoplasmic NN cord-015369-72cjogxz 7310 18 reticulum reticulum NN cord-015369-72cjogxz 7311 1 Ca ca RB cord-015369-72cjogxz 7311 2 2þ 2þ CD cord-015369-72cjogxz 7312 1 -ATPase -ATPase NNP cord-015369-72cjogxz 7313 1 ( ( -LRB- cord-015369-72cjogxz 7313 2 SERCA2a serca2a NN cord-015369-72cjogxz 7313 3 ) ) -RRB- cord-015369-72cjogxz 7313 4 responsible responsible JJ cord-015369-72cjogxz 7313 5 for for IN cord-015369-72cjogxz 7313 6 Ca Ca NNP cord-015369-72cjogxz 7313 7 2þ 2þ CD cord-015369-72cjogxz 7313 8 homeostasis homeostasis NN cord-015369-72cjogxz 7313 9 in in IN cord-015369-72cjogxz 7313 10 cardiac cardiac JJ cord-015369-72cjogxz 7313 11 muscle muscle NN cord-015369-72cjogxz 7313 12 . . . cord-015369-72cjogxz 7314 1 ACR ACR NNP cord-015369-72cjogxz 7314 2 is be VBZ cord-015369-72cjogxz 7314 3 associated associate VBN cord-015369-72cjogxz 7314 4 with with IN cord-015369-72cjogxz 7314 5 apoptosis apoptosis NN cord-015369-72cjogxz 7314 6 and and CC cord-015369-72cjogxz 7314 7 CRT CRT NNP cord-015369-72cjogxz 7314 8 induces induce VBZ cord-015369-72cjogxz 7314 9 apoptosis apoptosis NN cord-015369-72cjogxz 7314 10 in in IN cord-015369-72cjogxz 7314 11 mature mature JJ cord-015369-72cjogxz 7314 12 cardiomyocytes cardiomyocyte NNS cord-015369-72cjogxz 7314 13 . . . cord-015369-72cjogxz 7315 1 Whether whether IN cord-015369-72cjogxz 7315 2 myocardial myocardial JJ cord-015369-72cjogxz 7315 3 CRT CRT NNP cord-015369-72cjogxz 7315 4 expression expression NN cord-015369-72cjogxz 7315 5 plays play VBZ cord-015369-72cjogxz 7315 6 a a DT cord-015369-72cjogxz 7315 7 role role NN cord-015369-72cjogxz 7315 8 in in IN cord-015369-72cjogxz 7315 9 Ca Ca NNP cord-015369-72cjogxz 7315 10 2þ 2þ CD cord-015369-72cjogxz 7315 11 -dependent -dependent . cord-015369-72cjogxz 7316 1 apoptosis apoptosis NN cord-015369-72cjogxz 7316 2 in in IN cord-015369-72cjogxz 7316 3 ACR ACR NNP cord-015369-72cjogxz 7316 4 is be VBZ cord-015369-72cjogxz 7316 5 unknown unknown JJ cord-015369-72cjogxz 7316 6 . . . cord-015369-72cjogxz 7317 1 CRT CRT NNP cord-015369-72cjogxz 7317 2 and and CC cord-015369-72cjogxz 7317 3 SERCA2a serca2a NN cord-015369-72cjogxz 7317 4 mRNA mrna NN cord-015369-72cjogxz 7317 5 expression expression NN cord-015369-72cjogxz 7317 6 was be VBD cord-015369-72cjogxz 7317 7 quantified quantify VBN cord-015369-72cjogxz 7317 8 by by IN cord-015369-72cjogxz 7317 9 real real JJ cord-015369-72cjogxz 7317 10 time time NN cord-015369-72cjogxz 7317 11 RT RT NNP cord-015369-72cjogxz 7317 12 - - HYPH cord-015369-72cjogxz 7317 13 PCR PCR NNP cord-015369-72cjogxz 7317 14 in in IN cord-015369-72cjogxz 7317 15 routine routine JJ cord-015369-72cjogxz 7317 16 endomyocardial endomyocardial JJ cord-015369-72cjogxz 7317 17 biopsies biopsy NNS cord-015369-72cjogxz 7317 18 ( ( -LRB- cord-015369-72cjogxz 7317 19 EMBs EMBs NNP cord-015369-72cjogxz 7317 20 ) ) -RRB- cord-015369-72cjogxz 7317 21 of of IN cord-015369-72cjogxz 7317 22 transplanted transplant VBN cord-015369-72cjogxz 7317 23 patients patient NNS cord-015369-72cjogxz 7317 24 ( ( -LRB- cord-015369-72cjogxz 7317 25 n n NN cord-015369-72cjogxz 7317 26 ¼ ¼ NNP cord-015369-72cjogxz 7317 27 170 170 CD cord-015369-72cjogxz 7317 28 ) ) -RRB- cord-015369-72cjogxz 7317 29 at at IN cord-015369-72cjogxz 7317 30 1 1 CD cord-015369-72cjogxz 7317 31 , , , cord-015369-72cjogxz 7317 32 2 2 CD cord-015369-72cjogxz 7317 33 , , , cord-015369-72cjogxz 7317 34 3 3 CD cord-015369-72cjogxz 7317 35 , , , cord-015369-72cjogxz 7317 36 4 4 CD cord-015369-72cjogxz 7317 37 , , , cord-015369-72cjogxz 7317 38 7 7 CD cord-015369-72cjogxz 7317 39 , , , cord-015369-72cjogxz 7317 40 12 12 CD cord-015369-72cjogxz 7317 41 , , , cord-015369-72cjogxz 7317 42 24 24 CD cord-015369-72cjogxz 7317 43 and and CC cord-015369-72cjogxz 7317 44 52 52 CD cord-015369-72cjogxz 7317 45 weeks week NNS cord-015369-72cjogxz 7317 46 post post NN cord-015369-72cjogxz 7317 47 - - NN cord-015369-72cjogxz 7317 48 transplant transplant JJ cord-015369-72cjogxz 7317 49 and and CC cord-015369-72cjogxz 7317 50 when when WRB cord-015369-72cjogxz 7317 51 clinically clinically RB cord-015369-72cjogxz 7317 52 indicated indicate VBN cord-015369-72cjogxz 7317 53 . . . cord-015369-72cjogxz 7318 1 The the DT cord-015369-72cjogxz 7318 2 apoptotsis apoptotsis NN cord-015369-72cjogxz 7318 3 was be VBD cord-015369-72cjogxz 7318 4 assessed assess VBN cord-015369-72cjogxz 7318 5 in in IN cord-015369-72cjogxz 7318 6 EMBs emb NNS cord-015369-72cjogxz 7318 7 with with IN cord-015369-72cjogxz 7318 8 TUNEL TUNEL NNP cord-015369-72cjogxz 7318 9 assays assay NNS cord-015369-72cjogxz 7318 10 . . . cord-015369-72cjogxz 7319 1 Graft graft NN cord-015369-72cjogxz 7319 2 rejection rejection NN cord-015369-72cjogxz 7319 3 was be VBD cord-015369-72cjogxz 7319 4 histologically histologically RB cord-015369-72cjogxz 7319 5 diagnosed diagnose VBN cord-015369-72cjogxz 7319 6 and and CC cord-015369-72cjogxz 7319 7 scored score VBD cord-015369-72cjogxz 7319 8 according accord VBG cord-015369-72cjogxz 7319 9 to to IN cord-015369-72cjogxz 7319 10 ISHLT ISHLT NNP cord-015369-72cjogxz 7319 11 guidelines guideline NNS cord-015369-72cjogxz 7319 12 . . . cord-015369-72cjogxz 7320 1 Myocardial Myocardial NNP cord-015369-72cjogxz 7320 2 mRNA mRNA NNP cord-015369-72cjogxz 7320 3 expression expression NN cord-015369-72cjogxz 7320 4 of of IN cord-015369-72cjogxz 7320 5 CRT CRT NNP cord-015369-72cjogxz 7320 6 was be VBD cord-015369-72cjogxz 7320 7 significantly significantly RB cord-015369-72cjogxz 7320 8 increased increase VBN cord-015369-72cjogxz 7320 9 ( ( -LRB- cord-015369-72cjogxz 7320 10 p p NN cord-015369-72cjogxz 7320 11 < < XX cord-015369-72cjogxz 7320 12 0.04 0.04 CD cord-015369-72cjogxz 7320 13 ) ) -RRB- cord-015369-72cjogxz 7320 14 while while IN cord-015369-72cjogxz 7320 15 SERCA2a serca2a NN cord-015369-72cjogxz 7320 16 mRNA mrna NN cord-015369-72cjogxz 7320 17 levels level NNS cord-015369-72cjogxz 7320 18 were be VBD cord-015369-72cjogxz 7320 19 decreased decrease VBN cord-015369-72cjogxz 7320 20 ( ( -LRB- cord-015369-72cjogxz 7320 21 p p NN cord-015369-72cjogxz 7320 22 < < XX cord-015369-72cjogxz 7320 23 0.05 0.05 CD cord-015369-72cjogxz 7320 24 ) ) -RRB- cord-015369-72cjogxz 7320 25 in in IN cord-015369-72cjogxz 7320 26 ACR ACR NNP cord-015369-72cjogxz 7320 27 grades grade NNS cord-015369-72cjogxz 7320 28 1R-3R 1r-3r CD cord-015369-72cjogxz 7320 29 compared compare VBN cord-015369-72cjogxz 7320 30 to to IN cord-015369-72cjogxz 7320 31 EMBs emb NNS cord-015369-72cjogxz 7320 32 with with IN cord-015369-72cjogxz 7320 33 grade grade NN cord-015369-72cjogxz 7320 34 0 0 NFP cord-015369-72cjogxz 7320 35 at at IN cord-015369-72cjogxz 7320 36 all all RB cord-015369-72cjogxz 7320 37 post post JJ cord-015369-72cjogxz 7320 38 - - JJ cord-015369-72cjogxz 7320 39 transplant transplant JJ cord-015369-72cjogxz 7320 40 weeks week NNS cord-015369-72cjogxz 7320 41 . . . cord-015369-72cjogxz 7321 1 Moreover moreover RB cord-015369-72cjogxz 7321 2 , , , cord-015369-72cjogxz 7321 3 CRT CRT NNP cord-015369-72cjogxz 7321 4 mRNA mRNA NNP cord-015369-72cjogxz 7321 5 expression expression NN cord-015369-72cjogxz 7321 6 were be VBD cord-015369-72cjogxz 7321 7 significantly significantly RB cord-015369-72cjogxz 7321 8 elevated elevate VBN cord-015369-72cjogxz 7321 9 in in IN cord-015369-72cjogxz 7321 10 ACR ACR NNP cord-015369-72cjogxz 7321 11 grades grade NNS cord-015369-72cjogxz 7321 12 2R-3R 2r-3r CD cord-015369-72cjogxz 7321 13 compared compare VBN cord-015369-72cjogxz 7321 14 to to IN cord-015369-72cjogxz 7321 15 grade grade NN cord-015369-72cjogxz 7321 16 1R 1r CD cord-015369-72cjogxz 7321 17 ( ( -LRB- cord-015369-72cjogxz 7321 18 p p NN cord-015369-72cjogxz 7321 19 < < XX cord-015369-72cjogxz 7321 20 0.05 0.05 CD cord-015369-72cjogxz 7321 21 ) ) -RRB- cord-015369-72cjogxz 7321 22 . . . cord-015369-72cjogxz 7322 1 In in IN cord-015369-72cjogxz 7322 2 addition addition NN cord-015369-72cjogxz 7322 3 , , , cord-015369-72cjogxz 7322 4 significant significant JJ cord-015369-72cjogxz 7322 5 positive positive JJ cord-015369-72cjogxz 7322 6 correlation correlation NN cord-015369-72cjogxz 7322 7 between between IN cord-015369-72cjogxz 7322 8 increased increase VBN cord-015369-72cjogxz 7322 9 CRT CRT NNP cord-015369-72cjogxz 7322 10 expression expression NN cord-015369-72cjogxz 7322 11 ( ( -LRB- cord-015369-72cjogxz 7322 12 r r NNP cord-015369-72cjogxz 7322 13 s s NNP cord-015369-72cjogxz 7322 14 ¼ ¼ NNP cord-015369-72cjogxz 7322 15 0.8915 0.8915 CD cord-015369-72cjogxz 7322 16 ; ; : cord-015369-72cjogxz 7322 17 p p NN cord-015369-72cjogxz 7322 18 < < XX cord-015369-72cjogxz 7322 19 0.0001 0.0001 CD cord-015369-72cjogxz 7322 20 ) ) -RRB- cord-015369-72cjogxz 7322 21 and and CC cord-015369-72cjogxz 7322 22 negative negative JJ cord-015369-72cjogxz 7322 23 correlation correlation NN cord-015369-72cjogxz 7322 24 between between IN cord-015369-72cjogxz 7322 25 decreased decrease VBN cord-015369-72cjogxz 7322 26 SERCA2a serca2a NN cord-015369-72cjogxz 7322 27 ( ( -LRB- cord-015369-72cjogxz 7322 28 r r NNP cord-015369-72cjogxz 7322 29 s s NN cord-015369-72cjogxz 7322 30 ¼ ¼ NNP cord-015369-72cjogxz 7322 31 À0.7900 À0.7900 NNP cord-015369-72cjogxz 7322 32 ; ; : cord-015369-72cjogxz 7322 33 p p NN cord-015369-72cjogxz 7322 34 ¼ ¼ CD cord-015369-72cjogxz 7322 35 0.0005 0.0005 CD cord-015369-72cjogxz 7322 36 ) ) -RRB- cord-015369-72cjogxz 7322 37 and and CC cord-015369-72cjogxz 7323 1 the the DT cord-015369-72cjogxz 7323 2 degree degree NN cord-015369-72cjogxz 7323 3 of of IN cord-015369-72cjogxz 7323 4 EMB EMB NNP cord-015369-72cjogxz 7323 5 apoptosis apoptosis NN cord-015369-72cjogxz 7323 6 was be VBD cord-015369-72cjogxz 7323 7 observed observe VBN cord-015369-72cjogxz 7323 8 . . . cord-015369-72cjogxz 7324 1 These these DT cord-015369-72cjogxz 7324 2 results result NNS cord-015369-72cjogxz 7324 3 suggest suggest VBP cord-015369-72cjogxz 7324 4 that that IN cord-015369-72cjogxz 7324 5 CRT CRT NNP cord-015369-72cjogxz 7324 6 is be VBZ cord-015369-72cjogxz 7324 7 involved involve VBN cord-015369-72cjogxz 7324 8 in in IN cord-015369-72cjogxz 7324 9 disruption disruption NN cord-015369-72cjogxz 7324 10 of of IN cord-015369-72cjogxz 7324 11 intracellular intracellular JJ cord-015369-72cjogxz 7324 12 calcium calcium NN cord-015369-72cjogxz 7324 13 regulation regulation NN cord-015369-72cjogxz 7324 14 and and CC cord-015369-72cjogxz 7324 15 mediates mediate VBZ cord-015369-72cjogxz 7324 16 Ca Ca NNP cord-015369-72cjogxz 7324 17 2þ 2þ CD cord-015369-72cjogxz 7324 18 -dependent -dependent JJ cord-015369-72cjogxz 7324 19 cellular cellular JJ cord-015369-72cjogxz 7324 20 apoptosis apoptosis NN cord-015369-72cjogxz 7324 21 in in IN cord-015369-72cjogxz 7324 22 cardiac cardiac JJ cord-015369-72cjogxz 7324 23 grafts graft NNS cord-015369-72cjogxz 7324 24 with with IN cord-015369-72cjogxz 7324 25 ACR ACR NNP cord-015369-72cjogxz 7324 26 . . . cord-015369-72cjogxz 7325 1 Moreover moreover RB cord-015369-72cjogxz 7325 2 , , , cord-015369-72cjogxz 7325 3 assessment assessment NN cord-015369-72cjogxz 7325 4 of of IN cord-015369-72cjogxz 7325 5 CRT CRT NNP cord-015369-72cjogxz 7325 6 levels level NNS cord-015369-72cjogxz 7325 7 could could MD cord-015369-72cjogxz 7325 8 be be VB cord-015369-72cjogxz 7325 9 an an DT cord-015369-72cjogxz 7325 10 accurate accurate JJ cord-015369-72cjogxz 7325 11 and and CC cord-015369-72cjogxz 7325 12 quantitative quantitative JJ cord-015369-72cjogxz 7325 13 method method NN cord-015369-72cjogxz 7325 14 to to TO cord-015369-72cjogxz 7325 15 diagnose diagnose VB cord-015369-72cjogxz 7325 16 and and CC cord-015369-72cjogxz 7325 17 score score VB cord-015369-72cjogxz 7325 18 ACR ACR NNP cord-015369-72cjogxz 7325 19 . . . cord-015369-72cjogxz 7326 1 Further further JJ cord-015369-72cjogxz 7326 2 studies study NNS cord-015369-72cjogxz 7326 3 are be VBP cord-015369-72cjogxz 7326 4 necessary necessary JJ cord-015369-72cjogxz 7326 5 to to TO cord-015369-72cjogxz 7326 6 establish establish VB cord-015369-72cjogxz 7326 7 the the DT cord-015369-72cjogxz 7326 8 benefit benefit NN cord-015369-72cjogxz 7326 9 of of IN cord-015369-72cjogxz 7326 10 targeting target VBG cord-015369-72cjogxz 7326 11 CRT CRT NNP cord-015369-72cjogxz 7326 12 in in IN cord-015369-72cjogxz 7326 13 the the DT cord-015369-72cjogxz 7326 14 cardiac cardiac JJ cord-015369-72cjogxz 7326 15 ACR ACR NNP cord-015369-72cjogxz 7326 16 treatment treatment NN cord-015369-72cjogxz 7326 17 . . . cord-015369-72cjogxz 7327 1 Methodik Methodik NNP cord-015369-72cjogxz 7327 2 . . . cord-015369-72cjogxz 7328 1 I -PRON- PRP cord-015369-72cjogxz 7328 2 m be VBP cord-015369-72cjogxz 7328 3 Tierexperiment Tierexperiment NNP cord-015369-72cjogxz 7328 4 wurde wurde VBD cord-015369-72cjogxz 7328 5 bei bei NNP cord-015369-72cjogxz 7328 6 18 18 CD cord-015369-72cjogxz 7328 7 Schafen Schafen NNP cord-015369-72cjogxz 7328 8 am be VBP cord-015369-72cjogxz 7329 1 kardiopulmonalen kardiopulmonalen NNP cord-015369-72cjogxz 7329 2 Bypass Bypass NNP cord-015369-72cjogxz 7329 3 die die VB cord-015369-72cjogxz 7330 1 Aorta Aorta NNP cord-015369-72cjogxz 7330 2 ascendens ascendens NNP cord-015369-72cjogxz 7330 3 geklemmt geklemmt NNP cord-015369-72cjogxz 7330 4 und und IN cord-015369-72cjogxz 7330 5 kristalloide kristalloide NNP cord-015369-72cjogxz 7330 6 Kardioplegielösung Kardioplegielösung NNP cord-015369-72cjogxz 7330 7 infundiert infundiert NNP cord-015369-72cjogxz 7330 8 . . . cord-015369-72cjogxz 7331 1 Nach Nach NNP cord-015369-72cjogxz 7331 2 30 30 CD cord-015369-72cjogxz 7331 3 min min NN cord-015369-72cjogxz 7331 4 wurde wurde NNP cord-015369-72cjogxz 7331 5 nachkardioplegiert nachkardioplegiert NNP cord-015369-72cjogxz 7331 6 . . . cord-015369-72cjogxz 7332 1 In in IN cord-015369-72cjogxz 7332 2 der der NNP cord-015369-72cjogxz 7332 3 Gruppe Gruppe NNP cord-015369-72cjogxz 7332 4 I -PRON- PRP cord-015369-72cjogxz 7332 5 ( ( -LRB- cord-015369-72cjogxz 7332 6 n n NN cord-015369-72cjogxz 7332 7 ¼ ¼ NNP cord-015369-72cjogxz 7332 8 9 9 CD cord-015369-72cjogxz 7332 9 ) ) -RRB- cord-015369-72cjogxz 7332 10 wurde wurde NN cord-015369-72cjogxz 7332 11 NADH NADH NNP cord-015369-72cjogxz 7332 12 zur zur NNP cord-015369-72cjogxz 7332 13 Kardioplegielösung Kardioplegielösung NNP cord-015369-72cjogxz 7332 14 beigegeben beigegeben NN cord-015369-72cjogxz 7332 15 . . . cord-015369-72cjogxz 7333 1 In in IN cord-015369-72cjogxz 7333 2 der der NNP cord-015369-72cjogxz 7333 3 Kontrollgruppe Kontrollgruppe NNP cord-015369-72cjogxz 7333 4 ( ( -LRB- cord-015369-72cjogxz 7333 5 Gruppe Gruppe NNP cord-015369-72cjogxz 7333 6 II II NNP cord-015369-72cjogxz 7333 7 , , , cord-015369-72cjogxz 7333 8 n n NN cord-015369-72cjogxz 7333 9 ¼ ¼ NNP cord-015369-72cjogxz 7333 10 9 9 CD cord-015369-72cjogxz 7333 11 ) ) -RRB- cord-015369-72cjogxz 7333 12 wurde wurde NNP cord-015369-72cjogxz 7333 13 Kardioplegie Kardioplegie NNP cord-015369-72cjogxz 7333 14 ohne ohne NNP cord-015369-72cjogxz 7333 15 NADH NADH NNP cord-015369-72cjogxz 7333 16 Zusatz Zusatz NNP cord-015369-72cjogxz 7333 17 verwendet verwendet NNP cord-015369-72cjogxz 7333 18 . . . cord-015369-72cjogxz 7334 1 Nach Nach NNP cord-015369-72cjogxz 7334 2 60 60 CD cord-015369-72cjogxz 7334 3 min min NN cord-015369-72cjogxz 7334 4 wurde wurde NN cord-015369-72cjogxz 7334 5 die die VB cord-015369-72cjogxz 7335 1 Aortenklemme Aortenklemme NNP cord-015369-72cjogxz 7335 2 geöffnet geöffnet NNP cord-015369-72cjogxz 7335 3 und und NNP cord-015369-72cjogxz 7335 4 das das NNP cord-015369-72cjogxz 7335 5 Herz Herz NNP cord-015369-72cjogxz 7335 6 reperfundiert reperfundiert NNP cord-015369-72cjogxz 7335 7 . . . cord-015369-72cjogxz 7336 1 Nach Nach NNP cord-015369-72cjogxz 7336 2 einer einer NNP cord-015369-72cjogxz 7337 1 Reperfusionsphase Reperfusionsphase NNP cord-015369-72cjogxz 7337 2 von von NNP cord-015369-72cjogxz 7338 1 60 60 CD cord-015369-72cjogxz 7338 2 min min NN cord-015369-72cjogxz 7338 3 und und IN cord-015369-72cjogxz 7338 4 Stabilisierung Stabilisierung NNP cord-015369-72cjogxz 7338 5 der der NNP cord-015369-72cjogxz 7338 6 hämodynamischen hämodynamischen NNP cord-015369-72cjogxz 7338 7 und und IN cord-015369-72cjogxz 7338 8 elektrophysiologischen elektrophysiologischen NNP cord-015369-72cjogxz 7339 1 Parameter parameter NN cord-015369-72cjogxz 7339 2 wurde wurde NNP cord-015369-72cjogxz 7339 3 der der NNP cord-015369-72cjogxz 7339 4 kardiopulmonale kardiopulmonale NNP cord-015369-72cjogxz 7339 5 Bypass Bypass NNP cord-015369-72cjogxz 7339 6 beendet beendet NNP cord-015369-72cjogxz 7339 7 . . . cord-015369-72cjogxz 7340 1 Nach Nach NNP cord-015369-72cjogxz 7340 2 weiteren weiteren NNP cord-015369-72cjogxz 7341 1 60 60 CD cord-015369-72cjogxz 7341 2 min min NN cord-015369-72cjogxz 7341 3 wurden wurden NNP cord-015369-72cjogxz 7341 4 Myokardstücke Myokardstücke NNP cord-015369-72cjogxz 7341 5 aus aus NNP cord-015369-72cjogxz 7341 6 dem dem NNP cord-015369-72cjogxz 7341 7 linken linken NNP cord-015369-72cjogxz 7341 8 Ventrikel Ventrikel NNP cord-015369-72cjogxz 7341 9 entnommen entnommen NNP cord-015369-72cjogxz 7342 1 und und NNP cord-015369-72cjogxz 7343 1 mit mit NNP cord-015369-72cjogxz 7343 2 patch patch NN cord-015369-72cjogxz 7343 3 - - HYPH cord-015369-72cjogxz 7343 4 clamp clamp NN cord-015369-72cjogxz 7343 5 Technik Technik NNP cord-015369-72cjogxz 7343 6 untersucht untersucht NN cord-015369-72cjogxz 7343 7 . . . cord-015369-72cjogxz 7344 1 Weitere Weitere NNP cord-015369-72cjogxz 7344 2 Stücke Stücke NNP cord-015369-72cjogxz 7344 3 wurden wurden VBD cord-015369-72cjogxz 7344 4 mit mit NNP cord-015369-72cjogxz 7344 5 der der NNP cord-015369-72cjogxz 7344 6 Gefrierzange Gefrierzange NNP cord-015369-72cjogxz 7344 7 entnommen entnommen NNP cord-015369-72cjogxz 7344 8 und und IN cord-015369-72cjogxz 7344 9 in in IN cord-015369-72cjogxz 7344 10 flüssigem flüssigem NNS cord-015369-72cjogxz 7344 11 Stickstoff Stickstoff NNP cord-015369-72cjogxz 7344 12 bis bis NNP cord-015369-72cjogxz 7344 13 zur zur NNP cord-015369-72cjogxz 7344 14 weiteren weiteren NNP cord-015369-72cjogxz 7344 15 Analyse Analyse NNP cord-015369-72cjogxz 7344 16 gelagert gelagert NN cord-015369-72cjogxz 7344 17 . . . cord-015369-72cjogxz 7345 1 Ergebnisse Ergebnisse NNP cord-015369-72cjogxz 7345 2 . . . cord-015369-72cjogxz 7346 1 In in IN cord-015369-72cjogxz 7346 2 Gruppe Gruppe NNP cord-015369-72cjogxz 7346 3 I -PRON- PRP cord-015369-72cjogxz 7346 4 kam kam NNP cord-015369-72cjogxz 7346 5 es es XX cord-015369-72cjogxz 7346 6 zu zu NNP cord-015369-72cjogxz 7346 7 einem einem NNP cord-015369-72cjogxz 7346 8 signifikanten signifikanten NNP cord-015369-72cjogxz 7346 9 ATP ATP NNP cord-015369-72cjogxz 7346 10 Anstieg Anstieg NNP cord-015369-72cjogxz 7346 11 ( ( -LRB- cord-015369-72cjogxz 7346 12 p p NN cord-015369-72cjogxz 7346 13 < < XX cord-015369-72cjogxz 7346 14 0,05 0,05 XX cord-015369-72cjogxz 7346 15 ) ) -RRB- cord-015369-72cjogxz 7347 1 i -PRON- PRP cord-015369-72cjogxz 7347 2 m be VBP cord-015369-72cjogxz 7347 3 Vergleich Vergleich NNP cord-015369-72cjogxz 7347 4 zur zur NNP cord-015369-72cjogxz 7347 5 Kontrollgruppe Kontrollgruppe NNP cord-015369-72cjogxz 7347 6 . . . cord-015369-72cjogxz 7348 1 Der Der NNP cord-015369-72cjogxz 7348 2 Unterschied Unterschied NNP cord-015369-72cjogxz 7348 3 an an DT cord-015369-72cjogxz 7348 4 ATP ATP NNP cord-015369-72cjogxz 7348 5 Werten Werten NNP cord-015369-72cjogxz 7348 6 spiegelt spiegelt VBP cord-015369-72cjogxz 7348 7 eine eine NNP cord-015369-72cjogxz 7348 8 Verbesserung Verbesserung NNP cord-015369-72cjogxz 7348 9 des des FW cord-015369-72cjogxz 7348 10 metabolischen metabolischen NNP cord-015369-72cjogxz 7348 11 Zustandes Zustandes NNP cord-015369-72cjogxz 7348 12 in in IN cord-015369-72cjogxz 7348 13 der der NNP cord-015369-72cjogxz 7348 14 NADH NADH NNP cord-015369-72cjogxz 7348 15 Gruppe Gruppe NNP cord-015369-72cjogxz 7348 16 wider wider RBR cord-015369-72cjogxz 7348 17 . . . cord-015369-72cjogxz 7349 1 Weiters weiter NNS cord-015369-72cjogxz 7349 2 wurde wurde NN cord-015369-72cjogxz 7349 3 der der NNP cord-015369-72cjogxz 7349 4 Ladungszustand Ladungszustand NNP cord-015369-72cjogxz 7349 5 der der NNP cord-015369-72cjogxz 7349 6 Zellen Zellen NNP cord-015369-72cjogxz 7349 7 , , , cord-015369-72cjogxz 7349 8 der der NN cord-015369-72cjogxz 7349 9 den den NN cord-015369-72cjogxz 7349 10 Energiestatus Energiestatus NNP cord-015369-72cjogxz 7349 11 repräsentiert repräsentiert NN cord-015369-72cjogxz 7349 12 , , , cord-015369-72cjogxz 7349 13 verbessert verbessert NNP cord-015369-72cjogxz 7349 14 . . . cord-015369-72cjogxz 7350 1 Schlussfolgerungen Schlussfolgerungen NNP cord-015369-72cjogxz 7350 2 . . . cord-015369-72cjogxz 7351 1 NADH NADH NNP cord-015369-72cjogxz 7351 2 Zusatz Zusatz NNP cord-015369-72cjogxz 7351 3 könnte könnte NNP cord-015369-72cjogxz 7351 4 durch durch NNP cord-015369-72cjogxz 7351 5 seine seine FW cord-015369-72cjogxz 7351 6 positiven positiven NNP cord-015369-72cjogxz 7351 7 Effekte Effekte NNP cord-015369-72cjogxz 7351 8 auf auf NNP cord-015369-72cjogxz 7351 9 den den NN cord-015369-72cjogxz 7351 10 Metabolismus Metabolismus NNP cord-015369-72cjogxz 7351 11 in in IN cord-015369-72cjogxz 7351 12 Herzmuskelzellen Herzmuskelzellen NNP cord-015369-72cjogxz 7351 13 ein ein NNP cord-015369-72cjogxz 7351 14 potenter potenter NNP cord-015369-72cjogxz 7351 15 pharmakologischer pharmakologischer NNP cord-015369-72cjogxz 7351 16 und und XX cord-015369-72cjogxz 7352 1 therapeutischer therapeutischer NNP cord-015369-72cjogxz 7352 2 Ansatz Ansatz NNP cord-015369-72cjogxz 7352 3 sein sein NNP cord-015369-72cjogxz 7352 4 . . . cord-015369-72cjogxz 7353 1 Isolation isolation NN cord-015369-72cjogxz 7353 2 und und XX cord-015369-72cjogxz 7354 1 selektive selektive NNP cord-015369-72cjogxz 7354 2 Ablation Ablation NNP cord-015369-72cjogxz 7354 3 von von NNP cord-015369-72cjogxz 7354 4 Autonomen Autonomen NNP cord-015369-72cjogxz 7354 5 Ganglienplexus Ganglienplexus NNP cord-015369-72cjogxz 7354 6 bei bei NNP cord-015369-72cjogxz 7354 7 linksatrialer linksatrialer NN cord-015369-72cjogxz 7354 8 Vorhofablationcase Vorhofablationcase NNP cord-015369-72cjogxz 7354 9 report report NN cord-015369-72cjogxz 7354 10 Grundlagen Grundlagen NNP cord-015369-72cjogxz 7354 11 . . . cord-015369-72cjogxz 7355 1 Autonome Autonome NNP cord-015369-72cjogxz 7355 2 Ganglien Ganglien NNP cord-015369-72cjogxz 7355 3 - - HYPH cord-015369-72cjogxz 7355 4 Plexus Plexus NNP cord-015369-72cjogxz 7356 1 haben haben NNP cord-015369-72cjogxz 7356 2 als als NNP cord-015369-72cjogxz 7356 3 Trigger Trigger NNP cord-015369-72cjogxz 7356 4 einen einen NNP cord-015369-72cjogxz 7356 5 Einfluss Einfluss NNP cord-015369-72cjogxz 7356 6 auf auf NN cord-015369-72cjogxz 7356 7 die die VBP cord-015369-72cjogxz 7356 8 Entstehung Entstehung NNP cord-015369-72cjogxz 7356 9 von von NNP cord-015369-72cjogxz 7356 10 Vorhofflimmern Vorhofflimmern NNP cord-015369-72cjogxz 7356 11 . . . cord-015369-72cjogxz 7357 1 Durch Durch NNP cord-015369-72cjogxz 7357 2 selektive selektive NN cord-015369-72cjogxz 7357 3 Ablation ablation NN cord-015369-72cjogxz 7357 4 dieser dieser NNP cord-015369-72cjogxz 7358 1 Ganglien Ganglien NNP cord-015369-72cjogxz 7359 1 i i PRP cord-015369-72cjogxz 7360 1 m m NNP cord-015369-72cjogxz 7360 2 Rahmen Rahmen NNP cord-015369-72cjogxz 7360 3 der der NNP cord-015369-72cjogxz 7360 4 Pulmonalvenenisolation Pulmonalvenenisolation NNP cord-015369-72cjogxz 7360 5 konnte konnte NNP cord-015369-72cjogxz 7360 6 gezeigt gezeigt NNP cord-015369-72cjogxz 7360 7 werden werden NNP cord-015369-72cjogxz 7360 8 , , , cord-015369-72cjogxz 7360 9 dass dass NNP cord-015369-72cjogxz 7360 10 der der NNP cord-015369-72cjogxz 7360 11 Erfolg Erfolg NNP cord-015369-72cjogxz 7360 12 der der NNP cord-015369-72cjogxz 7360 13 Ablation Ablation NNP cord-015369-72cjogxz 7360 14 von von NNP cord-015369-72cjogxz 7361 1 70 70 CD cord-015369-72cjogxz 7361 2 % % NN cord-015369-72cjogxz 7362 1 auf auf NNP cord-015369-72cjogxz 7362 2 90 90 CD cord-015369-72cjogxz 7362 3 % % NN cord-015369-72cjogxz 7362 4 zunimmt zunimmt NNP cord-015369-72cjogxz 7362 5 . . . cord-015369-72cjogxz 7363 1 Methodik Methodik NNP cord-015369-72cjogxz 7363 2 . . . cord-015369-72cjogxz 7364 1 Bei Bei NNP cord-015369-72cjogxz 7364 2 einem einem NNP cord-015369-72cjogxz 7364 3 58-jährigen 58-jährigen CD cord-015369-72cjogxz 7364 4 Patienten Patienten NNP cord-015369-72cjogxz 7364 5 wurde wurde NN cord-015369-72cjogxz 7365 1 i -PRON- PRP cord-015369-72cjogxz 7365 2 m be VBP cord-015369-72cjogxz 7365 3 Rahmen Rahmen NNP cord-015369-72cjogxz 7365 4 der der NNP cord-015369-72cjogxz 7365 5 Mitralklappenrekonstruktion Mitralklappenrekonstruktion NNP cord-015369-72cjogxz 7365 6 wegen wegen NNP cord-015369-72cjogxz 7365 7 permanentem permanentem NNP cord-015369-72cjogxz 7365 8 Vorhofflimmern Vorhofflimmern NNP cord-015369-72cjogxz 7365 9 eine eine NNP cord-015369-72cjogxz 7365 10 linksatriale linksatriale JJ cord-015369-72cjogxz 7365 11 Vorhofablation Vorhofablation NNP cord-015369-72cjogxz 7365 12 mit mit NNP cord-015369-72cjogxz 7365 13 Medtronic Medtronic NNP cord-015369-72cjogxz 7365 14 Cardioblate Cardioblate NNP cord-015369-72cjogxz 7365 15 + + CC cord-015369-72cjogxz 7365 16 MAPS map NNS cord-015369-72cjogxz 7365 17 durchgeführt durchgeführt NN cord-015369-72cjogxz 7365 18 . . . cord-015369-72cjogxz 7366 1 Intraoperativ Intraoperativ NNP cord-015369-72cjogxz 7366 2 wurden wurden NNS cord-015369-72cjogxz 7366 3 die die VBP cord-015369-72cjogxz 7366 4 autonomen autonomen NNP cord-015369-72cjogxz 7367 1 Ganglien Ganglien NNP cord-015369-72cjogxz 7367 2 am be VBP cord-015369-72cjogxz 7367 3 rechten rechten NNP cord-015369-72cjogxz 7367 4 und und NNP cord-015369-72cjogxz 7367 5 linken linken NNP cord-015369-72cjogxz 7367 6 Atrium Atrium NNP cord-015369-72cjogxz 7368 1 durch durch NNP cord-015369-72cjogxz 7368 2 Hochfrequenzstimulation Hochfrequenzstimulation NNP cord-015369-72cjogxz 7368 3 am be VBP cord-015369-72cjogxz 7368 4 schlagenden schlagenden NNP cord-015369-72cjogxz 7368 5 Herzen Herzen NNP cord-015369-72cjogxz 7368 6 epikardial epikardial JJ cord-015369-72cjogxz 7368 7 isoliert isoliert NN cord-015369-72cjogxz 7368 8 . . . cord-015369-72cjogxz 7369 1 Als Als NNP cord-015369-72cjogxz 7369 2 positive positive JJ cord-015369-72cjogxz 7369 3 Antwort Antwort NNP cord-015369-72cjogxz 7369 4 wurde wurde NNP cord-015369-72cjogxz 7369 5 eine eine NNP cord-015369-72cjogxz 7370 1 Verlängerung Verlängerung NNP cord-015369-72cjogxz 7370 2 der der NNP cord-015369-72cjogxz 7370 3 RR RR NNP cord-015369-72cjogxz 7370 4 - - HYPH cord-015369-72cjogxz 7370 5 Intervalle Intervalle NNP cord-015369-72cjogxz 7371 1 um um UH cord-015369-72cjogxz 7371 2 mindestens mindestens NNP cord-015369-72cjogxz 7371 3 50 50 CD cord-015369-72cjogxz 7371 4 % % NN cord-015369-72cjogxz 7371 5 gewertet gewertet NN cord-015369-72cjogxz 7371 6 . . . cord-015369-72cjogxz 7372 1 Diese Diese NNP cord-015369-72cjogxz 7372 2 Stelle Stelle NNP cord-015369-72cjogxz 7372 3 wurde wurde NN cord-015369-72cjogxz 7372 4 mit mit NNP cord-015369-72cjogxz 7372 5 dem dem NNP cord-015369-72cjogxz 7372 6 Cardioblate Cardioblate NNP cord-015369-72cjogxz 7372 7 + + CC cord-015369-72cjogxz 7372 8 MAPS MAPS NNP cord-015369-72cjogxz 7372 9 Pen Pen NNP cord-015369-72cjogxz 7372 10 selektiv selektiv NN cord-015369-72cjogxz 7372 11 abliert abliert NN cord-015369-72cjogxz 7372 12 . . . cord-015369-72cjogxz 7373 1 Anschließend Anschließend NNP cord-015369-72cjogxz 7373 2 wurde wurde NNP cord-015369-72cjogxz 7373 3 am be VBP cord-015369-72cjogxz 7373 4 offenen offenen NNP cord-015369-72cjogxz 7373 5 Herzen Herzen NNP cord-015369-72cjogxz 7373 6 die die VBP cord-015369-72cjogxz 7373 7 endokardiale endokardiale NN cord-015369-72cjogxz 7373 8 Ablation ablation NN cord-015369-72cjogxz 7373 9 mit mit NNP cord-015369-72cjogxz 7373 10 Isolation isolation NN cord-015369-72cjogxz 7373 11 der der NNP cord-015369-72cjogxz 7373 12 Pul- Pul- NNP