id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-296229-pkwxlydz	Liu, Yang	The contribution of pre-symptomatic infection to the transmission dynamics of COVID-2019	2020-04-01		.txt	text/plain	2880	162	43	Methods: Using the probability for symptom onset on a given day inferred from the incubation period, we attributed the serial interval reported from Shenzen, China, into likely pre-symptomatic and symptomatic transmission. We did so by first using the incubation period density distribution to calculate the probability of having developed symptoms on each day since infection and then using this to stratify the serial interval distribution, assumed to be a proxy for the generation time, into likely pre-symptomatic and symptomatic onward transmissions. In the scenario of no active case finding and isolation before six days after symptom onset, and assuming uncorrelated serial interval and incubation period distributions, we estimate that 23% (range accounting for correlation: 12 -28%) of onward transmissions in Shenzen have occurred during the pre-symptomatic period ( Figure 2 and Table 1 ).	./cache/cord-296229-pkwxlydz.txt	./txt/cord-296229-pkwxlydz.txt