id author title date pages extension mime words sentences flesch summary cache txt cord-018714-i291z2ju Criado, Paulo Ricardo Adverse Drug Reactions 2016-12-31 .txt text/plain 23904 1177 38 • If possible identify the physiopathologic mechanism involved in the reaction; • Identify as rapidly as possible the drug inducing the reaction and always opt for its withdrawal; in some circumstances the choice is difficult as there is no alternative drug and its use is essential for the maintenance of life; • A careful and intensive observation is recommended for the occurrence of warning signs regarding the appearance of a potentially severe adverse drug reaction, especially in relation to mucous, oral, ocular, and genital involvement and progression of any present cutaneous eruption; • It is imperative that the drug responsible may be withdrawn on a permanent basis together with chemically related com-pounds, and this advice is also valid for first-degree relatives who can present the same type of reaction. ./cache/cord-018714-i291z2ju.txt ./txt/cord-018714-i291z2ju.txt