id author title date pages extension mime words sentences flesch summary cache txt cord-329648-ixzymz8a Niskanen, R. Failure to Spread Bovine Virus Diarrhoea Virus Infection from Primarily Infected Calves Despite Concurrent Infection with Bovine Coronavirus 2002-05-31 .txt text/plain 4286 221 58 In this study, the possibility of transmission of BVDV from calves simultaneously subjected to acute BVDV and bovine coronavirus (BCV) infection was investigated. Following infection, BCV was detected in nasal secretions and in faeces of the calves and, after three weeks in the study, all had seroconverted to this virus. All calves, including the controls, showed at least one of the following clinical signs during days 3–15 after the trial started: fever (≥40°C), depressed general condition, diarrhoea, and cough. Furthermore, BCV was introduced which should, in theory, facilitate the transmission of BVDV by causing increased nasal secretions, cough and diarrhoea, clinical signs that were indeed shown by the dually infected calves. All calves infected exclusively with BCV became diseased, which was regarded clinically as a sign of alimentary and respiratory tract involvement, i.e. diarrhoea, nasal and conjunctival discharge and coughing. Lack of virus transmission from primarily bovine viral diarrhoea virus (BVDV) infected calves to susceptible peers ./cache/cord-329648-ixzymz8a.txt ./txt/cord-329648-ixzymz8a.txt