id author title date pages extension mime words sentences flesch summary cache txt cord-274450-mukc7mxi Philippe, P. Comparative efficacy of diclazuril (Vecoxan(®)) and toltrazuril (Baycox bovis(®)) against natural infections of Eimeria bovis and Eimeria zuernii in French calves 2014-12-15 .txt text/plain 4316 212 56 A blinded, randomized, controlled, multi-centric field study was conducted on French dairy farms (n = 9) to evaluate the long term efficacy of metaphylactic, single oral treatments with either 1 mg/kg body weight (BW) of diclazuril (Vecoxan(®)), or 15 mg/kg BW of toltrazuril (Baycox(®)) against natural infections with Eimeria zuernii and/or Eimeria bovis, compared to untreated control animals. This study demonstrates that, over an extended observation period of 78 days, metaphylactic treatment with both diclazuril and toltrazuril reduces the impact of coccidiosis, but greater performance benefits based on average daily weight gains, were achieved following the use of diclazuril. Using a multiple linear regression model with mixed effect (data normally distributed, Shapiro-Wilk normality test, p-value = 0.5379), the diclazuril treated calves had an average daily gain (ADG) of 0.057 kg/day, significantly (p = 0.01) higher compared to calves in the toltrazuril group over the 11 weeks post-treatment observation period. ./cache/cord-274450-mukc7mxi.txt ./txt/cord-274450-mukc7mxi.txt