id author title date pages extension mime words sentences flesch summary cache txt cord-261338-gvlkc2r1 Foster, D.M. Pathophysiology of Diarrhea in Calves 2009-01-26 .txt text/plain 9387 517 45 Infectious diarrhea in calves is most commonly associated with enterotoxigenic Escherichia coli, Cryptosporidium parvum, rotavirus, coronavirus, or some combination of these pathogens. 63 Severity of diarrhea and incidence of clinical signs in calves shedding oocysts can be variable within and between farms, leading some to question the true importance of C parvum as a primary pathogen; 67 however, it has been repeatedly isolated independent of other known pathogens in clinical cases. 79 Specifically, research has shown that the activation and inhibition of apoptosis is Calf Diarrhea related to the life stage of C parvum, and that apoptosis is inhibited during the trophozoite stage when the organism is most dependent on the host, but then increases later during the infection. Epithelial cell loss, villous atrophy, and malabsorption cannot account for all the fluid loss seen in C parvum infections, and studies have documented a prostaglandin-mediated anion secretion (Cl � or HCO 3 � ) and inhibition of neutral NaCl absorption (Fig. 3) . ./cache/cord-261338-gvlkc2r1.txt ./txt/cord-261338-gvlkc2r1.txt