id author title date pages extension mime words sentences flesch summary cache txt cord-003782-my6frz5s Foster, Derek Exploratory cohort study to determine if dry cow vaccination with a Salmonella Newport bacterin can protect dairy calves against oral Salmonella challenge 2019-05-27 .txt text/plain 4702 261 54 title: Exploratory cohort study to determine if dry cow vaccination with a Salmonella Newport bacterin can protect dairy calves against oral Salmonella challenge HYPOTHESIS/OBJECTIVE: To evaluate the protective effect on calves of colostrum from cows vaccinated with a commercially available Salmonella Newport bacterin against a Salmonella Typhimurium challenge. Colostral immunity stimulated by vaccinating dry cows for Escherichia coli, rotavirus, and coronavirus has been used extensively in the dairy and beef industries to protect calves against diarrhea challenge. 8 This finding suggests that dry cow vaccination and subsequent colostrum administration may be a viable method to provide immunity against Salmonella in neonatal calves, potentially decreasing the incidence, severity, and mortality of the infection. Secondary outcomes also were evaluated to determine if consumption of colostrum from vaccinated cows would impact the titers, clinical disease, or shedding of Salmonella in calves after experimental infection. Administration of the Salmonella Newport bacterin to dry cows did not provide protective immunity to calves in our study despite increased titers. ./cache/cord-003782-my6frz5s.txt ./txt/cord-003782-my6frz5s.txt