id	sid	tid	token	lemma	pos
cord-016871-1mlamf20	1	1	key	key	JJ
cord-016871-1mlamf20	1	2	:	:	:
cord-016871-1mlamf20	1	3	cord-016871	cord-016871	CD
cord-016871-1mlamf20	1	4	-	-	HYPH
cord-016871-1mlamf20	1	5	1mlamf20	1mlamf20	JJ
cord-016871-1mlamf20	1	6	authors	author	NNS
cord-016871-1mlamf20	1	7	:	:	:
cord-016871-1mlamf20	1	8	Streiff	Streiff	NNP
cord-016871-1mlamf20	1	9	,	,	,
cord-016871-1mlamf20	1	10	Agathe	Agathe	NNP
cord-016871-1mlamf20	1	11	;	;	:
cord-016871-1mlamf20	1	12	Cotton	Cotton	NNP
cord-016871-1mlamf20	1	13	,	,	,
cord-016871-1mlamf20	1	14	Bryan	Bryan	NNP
cord-016871-1mlamf20	1	15	A.	a.	NN
cord-016871-1mlamf20	1	16	title	title	NN
cord-016871-1mlamf20	1	17	:	:	:
cord-016871-1mlamf20	1	18	Hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	1	19	and	and	CC
cord-016871-1mlamf20	1	20	Transfusions	transfusion	NNS
cord-016871-1mlamf20	1	21	in	in	IN
cord-016871-1mlamf20	1	22	the	the	DT
cord-016871-1mlamf20	1	23	Surgical	surgical	JJ
cord-016871-1mlamf20	1	24	Patient	Patient	NNP
cord-016871-1mlamf20	1	25	date	date	NN
cord-016871-1mlamf20	1	26	:	:	:
cord-016871-1mlamf20	1	27	2012	2012	CD
cord-016871-1mlamf20	1	28	-	-	SYM
cord-016871-1mlamf20	1	29	10	10	CD
cord-016871-1mlamf20	1	30	-	-	SYM
cord-016871-1mlamf20	1	31	30	30	CD
cord-016871-1mlamf20	1	32	journal	journal	NN
cord-016871-1mlamf20	1	33	:	:	:
cord-016871-1mlamf20	1	34	Common	common	JJ
cord-016871-1mlamf20	1	35	Problems	Problems	NNPS
cord-016871-1mlamf20	1	36	in	in	IN
cord-016871-1mlamf20	1	37	Acute	Acute	NNP
cord-016871-1mlamf20	1	38	Care	Care	NNP
cord-016871-1mlamf20	1	39	Surgery	surgery	NN
cord-016871-1mlamf20	2	1	DOI	DOI	NNP
cord-016871-1mlamf20	2	2	:	:	:
cord-016871-1mlamf20	3	1	10.1007/978	10.1007/978	LS
cord-016871-1mlamf20	3	2	-	-	HYPH
cord-016871-1mlamf20	3	3	1	1	CD
cord-016871-1mlamf20	3	4	-	-	HYPH
cord-016871-1mlamf20	3	5	4614	4614	CD
cord-016871-1mlamf20	3	6	-	-	HYPH
cord-016871-1mlamf20	3	7	6123	6123	CD
cord-016871-1mlamf20	3	8	-	-	HYPH
cord-016871-1mlamf20	3	9	4_12	4_12	CD
cord-016871-1mlamf20	3	10	sha	sha	NNP
cord-016871-1mlamf20	3	11	:	:	:
cord-016871-1mlamf20	4	1	8576648bca15f349295cf63efe0199da851d9ac2	8576648bca15f349295cf63efe0199da851d9ac2	CD
cord-016871-1mlamf20	4	2	doc_id	doc_id	CD
cord-016871-1mlamf20	4	3	:	:	:
cord-016871-1mlamf20	4	4	16871	16871	CD
cord-016871-1mlamf20	5	1	cord_uid	cord_uid	NN
cord-016871-1mlamf20	5	2	:	:	:
cord-016871-1mlamf20	6	1	1mlamf20	1mlamf20	LS
cord-016871-1mlamf20	6	2	Hemorrhage	Hemorrhage	NNP
cord-016871-1mlamf20	6	3	is	be	VBZ
cord-016871-1mlamf20	6	4	the	the	DT
cord-016871-1mlamf20	6	5	leading	leading	JJ
cord-016871-1mlamf20	6	6	cause	cause	NN
cord-016871-1mlamf20	6	7	of	of	IN
cord-016871-1mlamf20	6	8	intraoperative	intraoperative	JJ
cord-016871-1mlamf20	6	9	deaths	death	NNS
cord-016871-1mlamf20	6	10	.	.	.
cord-016871-1mlamf20	7	1	Many	many	JJ
cord-016871-1mlamf20	7	2	cardiovascular	cardiovascular	JJ
cord-016871-1mlamf20	7	3	and	and	CC
cord-016871-1mlamf20	7	4	hepatobiliary	hepatobiliary	JJ
cord-016871-1mlamf20	7	5	procedures	procedure	NNS
cord-016871-1mlamf20	7	6	result	result	VBP
cord-016871-1mlamf20	7	7	in	in	IN
cord-016871-1mlamf20	7	8	massive	massive	JJ
cord-016871-1mlamf20	7	9	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	7	10	and	and	CC
cord-016871-1mlamf20	7	11	postpartum	postpartum	NN
cord-016871-1mlamf20	7	12	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	7	13	events	event	NNS
cord-016871-1mlamf20	7	14	in	in	IN
cord-016871-1mlamf20	7	15	labor	labor	NN
cord-016871-1mlamf20	7	16	and	and	CC
cord-016871-1mlamf20	7	17	delivery	delivery	NN
cord-016871-1mlamf20	7	18	place	place	NN
cord-016871-1mlamf20	7	19	the	the	DT
cord-016871-1mlamf20	7	20	patient	patient	NN
cord-016871-1mlamf20	7	21	at	at	IN
cord-016871-1mlamf20	7	22	a	a	DT
cord-016871-1mlamf20	7	23	high	high	JJ
cord-016871-1mlamf20	7	24	risk	risk	NN
cord-016871-1mlamf20	7	25	for	for	IN
cord-016871-1mlamf20	7	26	mortality	mortality	NN
cord-016871-1mlamf20	7	27	.	.	.
cord-016871-1mlamf20	8	1	Gastrointestinal	gastrointestinal	JJ
cord-016871-1mlamf20	8	2	bleeding	bleed	VBG
cord-016871-1mlamf20	8	3	from	from	IN
cord-016871-1mlamf20	8	4	diverticulosis	diverticulosis	NN
cord-016871-1mlamf20	8	5	,	,	,
cord-016871-1mlamf20	8	6	varices	varix	NNS
cord-016871-1mlamf20	8	7	,	,	,
cord-016871-1mlamf20	8	8	and	and	CC
cord-016871-1mlamf20	8	9	ulcer	ulcer	NN
cord-016871-1mlamf20	8	10	disease	disease	NN
cord-016871-1mlamf20	8	11	can	can	MD
cord-016871-1mlamf20	8	12	result	result	VB
cord-016871-1mlamf20	8	13	in	in	IN
cord-016871-1mlamf20	8	14	significant	significant	JJ
cord-016871-1mlamf20	8	15	blood	blood	NN
cord-016871-1mlamf20	8	16	loss	loss	NN
cord-016871-1mlamf20	8	17	requiring	require	VBG
cord-016871-1mlamf20	8	18	massive	massive	JJ
cord-016871-1mlamf20	8	19	transfusion	transfusion	NN
cord-016871-1mlamf20	8	20	and	and	CC
cord-016871-1mlamf20	8	21	resuscitation	resuscitation	NN
cord-016871-1mlamf20	8	22	from	from	IN
cord-016871-1mlamf20	8	23	hemorrhagic	hemorrhagic	JJ
cord-016871-1mlamf20	8	24	shock	shock	NN
cord-016871-1mlamf20	8	25	.	.	.
cord-016871-1mlamf20	9	1	Timely	timely	JJ
cord-016871-1mlamf20	9	2	and	and	CC
cord-016871-1mlamf20	9	3	effective	effective	JJ
cord-016871-1mlamf20	9	4	transfusion	transfusion	NN
cord-016871-1mlamf20	9	5	of	of	IN
cord-016871-1mlamf20	9	6	blood	blood	NN
cord-016871-1mlamf20	9	7	products	product	NNS
cord-016871-1mlamf20	9	8	is	be	VBZ
cord-016871-1mlamf20	9	9	of	of	IN
cord-016871-1mlamf20	9	10	critical	critical	JJ
cord-016871-1mlamf20	9	11	in	in	IN
cord-016871-1mlamf20	9	12	these	these	DT
cord-016871-1mlamf20	9	13	scenarios	scenario	NNS
cord-016871-1mlamf20	9	14	.	.	.
cord-016871-1mlamf20	10	1	The	the	DT
cord-016871-1mlamf20	10	2	frequency	frequency	NN
cord-016871-1mlamf20	10	3	in	in	IN
cord-016871-1mlamf20	10	4	which	which	WDT
cord-016871-1mlamf20	10	5	blood	blood	NN
cord-016871-1mlamf20	10	6	component	component	NN
cord-016871-1mlamf20	10	7	products	product	NNS
cord-016871-1mlamf20	10	8	are	be	VBP
cord-016871-1mlamf20	10	9	transfused	transfuse	VBN
cord-016871-1mlamf20	10	10	in	in	IN
cord-016871-1mlamf20	10	11	surgical	surgical	JJ
cord-016871-1mlamf20	10	12	patients	patient	NNS
cord-016871-1mlamf20	10	13	begs	beg	VBZ
cord-016871-1mlamf20	10	14	for	for	IN
cord-016871-1mlamf20	10	15	a	a	DT
cord-016871-1mlamf20	10	16	greater	great	JJR
cord-016871-1mlamf20	10	17	understanding	understanding	NN
cord-016871-1mlamf20	10	18	of	of	IN
cord-016871-1mlamf20	10	19	them	-PRON-	PRP
cord-016871-1mlamf20	10	20	.	.	.
cord-016871-1mlamf20	11	1	The	the	DT
cord-016871-1mlamf20	11	2	aim	aim	NN
cord-016871-1mlamf20	11	3	of	of	IN
cord-016871-1mlamf20	11	4	this	this	DT
cord-016871-1mlamf20	11	5	chapter	chapter	NN
cord-016871-1mlamf20	11	6	is	be	VBZ
cord-016871-1mlamf20	11	7	to	to	TO
cord-016871-1mlamf20	11	8	provide	provide	VB
cord-016871-1mlamf20	11	9	clinicians	clinician	NNS
cord-016871-1mlamf20	11	10	with	with	IN
cord-016871-1mlamf20	11	11	a	a	DT
cord-016871-1mlamf20	11	12	discussion	discussion	NN
cord-016871-1mlamf20	11	13	of	of	IN
cord-016871-1mlamf20	11	14	the	the	DT
cord-016871-1mlamf20	11	15	current	current	JJ
cord-016871-1mlamf20	11	16	literature	literature	NN
cord-016871-1mlamf20	11	17	on	on	IN
cord-016871-1mlamf20	11	18	the	the	DT
cord-016871-1mlamf20	11	19	various	various	JJ
cord-016871-1mlamf20	11	20	blood	blood	NN
cord-016871-1mlamf20	11	21	component	component	NN
cord-016871-1mlamf20	11	22	products	product	NNS
cord-016871-1mlamf20	11	23	,	,	,
cord-016871-1mlamf20	11	24	their	-PRON-	PRP$
cord-016871-1mlamf20	11	25	indications	indication	NNS
cord-016871-1mlamf20	11	26	,	,	,
cord-016871-1mlamf20	11	27	and	and	CC
cord-016871-1mlamf20	11	28	unique	unique	JJ
cord-016871-1mlamf20	11	29	hemostatic	hemostatic	JJ
cord-016871-1mlamf20	11	30	conditions	condition	NNS
cord-016871-1mlamf20	11	31	in	in	IN
cord-016871-1mlamf20	11	32	the	the	DT
cord-016871-1mlamf20	11	33	surgical	surgical	JJ
cord-016871-1mlamf20	11	34	patient	patient	NN
cord-016871-1mlamf20	11	35	.	.	.
cord-016871-1mlamf20	12	1	While	while	IN
cord-016871-1mlamf20	12	2	the	the	DT
cord-016871-1mlamf20	12	3	majority	majority	NN
cord-016871-1mlamf20	12	4	of	of	IN
cord-016871-1mlamf20	12	5	data	datum	NNS
cord-016871-1mlamf20	12	6	concerning	concern	VBG
cord-016871-1mlamf20	12	7	optimal	optimal	JJ
cord-016871-1mlamf20	12	8	management	management	NN
cord-016871-1mlamf20	12	9	of	of	IN
cord-016871-1mlamf20	12	10	acquired	acquire	VBN
cord-016871-1mlamf20	12	11	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	12	12	and	and	CC
cord-016871-1mlamf20	12	13	hemorrhagic	hemorrhagic	JJ
cord-016871-1mlamf20	12	14	shock	shock	NN
cord-016871-1mlamf20	12	15	resuscitation	resuscitation	NN
cord-016871-1mlamf20	12	16	is	be	VBZ
cord-016871-1mlamf20	12	17	based	base	VBN
cord-016871-1mlamf20	12	18	on	on	IN
cord-016871-1mlamf20	12	19	trauma	trauma	NN
cord-016871-1mlamf20	12	20	patients	patient	NNS
cord-016871-1mlamf20	12	21	,	,	,
cord-016871-1mlamf20	12	22	many	many	JJ
cord-016871-1mlamf20	12	23	of	of	IN
cord-016871-1mlamf20	12	24	the	the	DT
cord-016871-1mlamf20	12	25	principles	principle	NNS
cord-016871-1mlamf20	12	26	can	can	MD
cord-016871-1mlamf20	12	27	and	and	CC
cord-016871-1mlamf20	12	28	should	should	MD
cord-016871-1mlamf20	12	29	be	be	VB
cord-016871-1mlamf20	12	30	applied	apply	VBN
cord-016871-1mlamf20	12	31	to	to	IN
cord-016871-1mlamf20	12	32	the	the	DT
cord-016871-1mlamf20	12	33	surgical	surgical	JJ
cord-016871-1mlamf20	12	34	patient	patient	NN
cord-016871-1mlamf20	12	35	(	(	-LRB-
cord-016871-1mlamf20	12	36	or	or	CC
cord-016871-1mlamf20	12	37	likely	likely	RB
cord-016871-1mlamf20	12	38	any	any	DT
cord-016871-1mlamf20	12	39	patient	patient	NN
cord-016871-1mlamf20	12	40	)	)	-RRB-
cord-016871-1mlamf20	12	41	with	with	IN
cord-016871-1mlamf20	12	42	profound	profound	JJ
cord-016871-1mlamf20	12	43	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	12	44	.	.	.
cord-016871-1mlamf20	13	1	Hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	13	2	is	be	VBZ
cord-016871-1mlamf20	13	3	the	the	DT
cord-016871-1mlamf20	13	4	leading	leading	JJ
cord-016871-1mlamf20	13	5	cause	cause	NN
cord-016871-1mlamf20	13	6	of	of	IN
cord-016871-1mlamf20	13	7	intraoperative	intraoperative	JJ
cord-016871-1mlamf20	13	8	deaths	death	NNS
cord-016871-1mlamf20	13	9	.	.	.
cord-016871-1mlamf20	14	1	Many	many	JJ
cord-016871-1mlamf20	14	2	cardiovascular	cardiovascular	JJ
cord-016871-1mlamf20	14	3	and	and	CC
cord-016871-1mlamf20	14	4	hepatobiliary	hepatobiliary	JJ
cord-016871-1mlamf20	14	5	procedures	procedure	NNS
cord-016871-1mlamf20	14	6	result	result	VBP
cord-016871-1mlamf20	14	7	in	in	IN
cord-016871-1mlamf20	14	8	massive	massive	JJ
cord-016871-1mlamf20	14	9	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	14	10	and	and	CC
cord-016871-1mlamf20	14	11	postpartum	postpartum	NN
cord-016871-1mlamf20	14	12	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	14	13	events	event	NNS
cord-016871-1mlamf20	14	14	in	in	IN
cord-016871-1mlamf20	14	15	labor	labor	NN
cord-016871-1mlamf20	14	16	and	and	CC
cord-016871-1mlamf20	14	17	delivery	delivery	NN
cord-016871-1mlamf20	14	18	place	place	NN
cord-016871-1mlamf20	14	19	the	the	DT
cord-016871-1mlamf20	14	20	patient	patient	NN
cord-016871-1mlamf20	14	21	at	at	IN
cord-016871-1mlamf20	14	22	a	a	DT
cord-016871-1mlamf20	14	23	high	high	JJ
cord-016871-1mlamf20	14	24	risk	risk	NN
cord-016871-1mlamf20	14	25	for	for	IN
cord-016871-1mlamf20	14	26	mortality	mortality	NN
cord-016871-1mlamf20	14	27	.	.	.
cord-016871-1mlamf20	15	1	Gastrointestinal	gastrointestinal	JJ
cord-016871-1mlamf20	15	2	bleeding	bleed	VBG
cord-016871-1mlamf20	15	3	from	from	IN
cord-016871-1mlamf20	15	4	diverticulosis	diverticulosis	NN
cord-016871-1mlamf20	15	5	,	,	,
cord-016871-1mlamf20	15	6	varices	varix	NNS
cord-016871-1mlamf20	15	7	,	,	,
cord-016871-1mlamf20	15	8	and	and	CC
cord-016871-1mlamf20	15	9	ulcer	ulcer	NN
cord-016871-1mlamf20	15	10	disease	disease	NN
cord-016871-1mlamf20	15	11	can	can	MD
cord-016871-1mlamf20	15	12	result	result	VB
cord-016871-1mlamf20	15	13	in	in	IN
cord-016871-1mlamf20	15	14	signi	signi	NNP
cord-016871-1mlamf20	15	15	fi	fi	NNP
cord-016871-1mlamf20	15	16	ca	can	MD
cord-016871-1mlamf20	15	17	nt	not	RB
cord-016871-1mlamf20	15	18	blood	blood	NN
cord-016871-1mlamf20	15	19	loss	loss	NN
cord-016871-1mlamf20	15	20	requiring	require	VBG
cord-016871-1mlamf20	15	21	massive	massive	JJ
cord-016871-1mlamf20	15	22	transfusion	transfusion	NN
cord-016871-1mlamf20	15	23	and	and	CC
cord-016871-1mlamf20	15	24	resuscitation	resuscitation	NN
cord-016871-1mlamf20	15	25	from	from	IN
cord-016871-1mlamf20	15	26	hemorrhagic	hemorrhagic	JJ
cord-016871-1mlamf20	15	27	shock	shock	NN
cord-016871-1mlamf20	15	28	.	.	.
cord-016871-1mlamf20	16	1	Timely	timely	JJ
cord-016871-1mlamf20	16	2	and	and	CC
cord-016871-1mlamf20	16	3	effective	effective	JJ
cord-016871-1mlamf20	16	4	transfusion	transfusion	NN
cord-016871-1mlamf20	16	5	of	of	IN
cord-016871-1mlamf20	16	6	blood	blood	NN
cord-016871-1mlamf20	16	7	products	product	NNS
cord-016871-1mlamf20	16	8	is	be	VBZ
cord-016871-1mlamf20	16	9	of	of	IN
cord-016871-1mlamf20	16	10	critical	critical	JJ
cord-016871-1mlamf20	16	11	in	in	IN
cord-016871-1mlamf20	16	12	these	these	DT
cord-016871-1mlamf20	16	13	scenarios	scenario	NNS
cord-016871-1mlamf20	16	14	.	.	.
cord-016871-1mlamf20	17	1	The	the	DT
cord-016871-1mlamf20	17	2	frequency	frequency	NN
cord-016871-1mlamf20	17	3	in	in	IN
cord-016871-1mlamf20	17	4	which	which	WDT
cord-016871-1mlamf20	17	5	blood	blood	NN
cord-016871-1mlamf20	17	6	component	component	NN
cord-016871-1mlamf20	17	7	products	product	NNS
cord-016871-1mlamf20	17	8	are	be	VBP
cord-016871-1mlamf20	17	9	transfused	transfuse	VBN
cord-016871-1mlamf20	17	10	in	in	IN
cord-016871-1mlamf20	17	11	surgical	surgical	JJ
cord-016871-1mlamf20	17	12	patients	patient	NNS
cord-016871-1mlamf20	17	13	begs	beg	VBZ
cord-016871-1mlamf20	17	14	for	for	IN
cord-016871-1mlamf20	17	15	a	a	DT
cord-016871-1mlamf20	17	16	greater	great	JJR
cord-016871-1mlamf20	17	17	understanding	understanding	NN
cord-016871-1mlamf20	17	18	of	of	IN
cord-016871-1mlamf20	17	19	them	-PRON-	PRP
cord-016871-1mlamf20	17	20	.	.	.
cord-016871-1mlamf20	18	1	The	the	DT
cord-016871-1mlamf20	18	2	aim	aim	NN
cord-016871-1mlamf20	18	3	of	of	IN
cord-016871-1mlamf20	18	4	this	this	DT
cord-016871-1mlamf20	18	5	chapter	chapter	NN
cord-016871-1mlamf20	18	6	is	be	VBZ
cord-016871-1mlamf20	18	7	to	to	TO
cord-016871-1mlamf20	18	8	provide	provide	VB
cord-016871-1mlamf20	18	9	clinicians	clinician	NNS
cord-016871-1mlamf20	18	10	with	with	IN
cord-016871-1mlamf20	18	11	a	a	DT
cord-016871-1mlamf20	18	12	discussion	discussion	NN
cord-016871-1mlamf20	18	13	of	of	IN
cord-016871-1mlamf20	18	14	the	the	DT
cord-016871-1mlamf20	18	15	current	current	JJ
cord-016871-1mlamf20	18	16	literature	literature	NN
cord-016871-1mlamf20	18	17	on	on	IN
cord-016871-1mlamf20	18	18	the	the	DT
cord-016871-1mlamf20	18	19	various	various	JJ
cord-016871-1mlamf20	18	20	blood	blood	NN
cord-016871-1mlamf20	18	21	component	component	NN
cord-016871-1mlamf20	18	22	products	product	NNS
cord-016871-1mlamf20	18	23	,	,	,
cord-016871-1mlamf20	18	24	their	-PRON-	PRP$
cord-016871-1mlamf20	18	25	indications	indication	NNS
cord-016871-1mlamf20	18	26	,	,	,
cord-016871-1mlamf20	18	27	and	and	CC
cord-016871-1mlamf20	18	28	unique	unique	JJ
cord-016871-1mlamf20	18	29	hemostatic	hemostatic	JJ
cord-016871-1mlamf20	18	30	conditions	condition	NNS
cord-016871-1mlamf20	18	31	in	in	IN
cord-016871-1mlamf20	18	32	the	the	DT
cord-016871-1mlamf20	18	33	surgical	surgical	JJ
cord-016871-1mlamf20	18	34	patient	patient	NN
cord-016871-1mlamf20	18	35	.	.	.
cord-016871-1mlamf20	19	1	While	while	IN
cord-016871-1mlamf20	19	2	the	the	DT
cord-016871-1mlamf20	19	3	majority	majority	NN
cord-016871-1mlamf20	19	4	of	of	IN
cord-016871-1mlamf20	19	5	data	datum	NNS
cord-016871-1mlamf20	19	6	concerning	concern	VBG
cord-016871-1mlamf20	19	7	optimal	optimal	JJ
cord-016871-1mlamf20	19	8	management	management	NN
cord-016871-1mlamf20	19	9	of	of	IN
cord-016871-1mlamf20	19	10	acquired	acquire	VBN
cord-016871-1mlamf20	19	11	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	19	12	and	and	CC
cord-016871-1mlamf20	19	13	hemorrhagic	hemorrhagic	JJ
cord-016871-1mlamf20	19	14	shock	shock	NN
cord-016871-1mlamf20	19	15	resuscitation	resuscitation	NN
cord-016871-1mlamf20	19	16	is	be	VBZ
cord-016871-1mlamf20	19	17	based	base	VBN
cord-016871-1mlamf20	19	18	on	on	IN
cord-016871-1mlamf20	19	19	trauma	trauma	NN
cord-016871-1mlamf20	19	20	patients	patient	NNS
cord-016871-1mlamf20	19	21	,	,	,
cord-016871-1mlamf20	19	22	many	many	JJ
cord-016871-1mlamf20	19	23	of	of	IN
cord-016871-1mlamf20	19	24	the	the	DT
cord-016871-1mlamf20	19	25	principles	principle	NNS
cord-016871-1mlamf20	19	26	can	can	MD
cord-016871-1mlamf20	19	27	and	and	CC
cord-016871-1mlamf20	19	28	should	should	MD
cord-016871-1mlamf20	19	29	be	be	VB
cord-016871-1mlamf20	19	30	applied	apply	VBN
cord-016871-1mlamf20	19	31	to	to	IN
cord-016871-1mlamf20	19	32	the	the	DT
cord-016871-1mlamf20	19	33	surgical	surgical	JJ
cord-016871-1mlamf20	19	34	patient	patient	NN
cord-016871-1mlamf20	19	35	(	(	-LRB-
cord-016871-1mlamf20	19	36	or	or	CC
cord-016871-1mlamf20	19	37	likely	likely	RB
cord-016871-1mlamf20	19	38	any	any	DT
cord-016871-1mlamf20	19	39	patient	patient	NN
cord-016871-1mlamf20	19	40	)	)	-RRB-
cord-016871-1mlamf20	19	41	with	with	IN
cord-016871-1mlamf20	19	42	profound	profound	JJ
cord-016871-1mlamf20	19	43	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	19	44	.	.	.
cord-016871-1mlamf20	20	1	The	the	DT
cord-016871-1mlamf20	20	2	concept	concept	NN
cord-016871-1mlamf20	20	3	of	of	IN
cord-016871-1mlamf20	20	4	the	the	DT
cord-016871-1mlamf20	20	5	lethal	lethal	JJ
cord-016871-1mlamf20	20	6	triad	triad	NN
cord-016871-1mlamf20	20	7	-	-	HYPH
cord-016871-1mlamf20	20	8	hypothermia	hypothermia	NN
cord-016871-1mlamf20	20	9	,	,	,
cord-016871-1mlamf20	20	10	acidosis	acidosis	NN
cord-016871-1mlamf20	20	11	and	and	CC
cord-016871-1mlamf20	20	12	coagulation	coagulation	NN
cord-016871-1mlamf20	20	13	-	-	,
cord-016871-1mlamf20	20	14	was	be	VBD
cord-016871-1mlamf20	20	15	fi	fi	NNP
cord-016871-1mlamf20	20	16	rst	rst	NNP
cord-016871-1mlamf20	20	17	promoted	promote	VBN
cord-016871-1mlamf20	20	18	in	in	IN
cord-016871-1mlamf20	20	19	the	the	DT
cord-016871-1mlamf20	20	20	trauma	trauma	NN
cord-016871-1mlamf20	20	21	population	population	NN
cord-016871-1mlamf20	20	22	in	in	IN
cord-016871-1mlamf20	20	23	those	those	DT
cord-016871-1mlamf20	20	24	undergoing	undergo	VBG
cord-016871-1mlamf20	20	25	emergency	emergency	NN
cord-016871-1mlamf20	20	26	surgery	surgery	NN
cord-016871-1mlamf20	20	27	.	.	.
cord-016871-1mlamf20	21	1	In	in	IN
cord-016871-1mlamf20	21	2	an	an	DT
cord-016871-1mlamf20	21	3	effort	effort	NN
cord-016871-1mlamf20	21	4	to	to	TO
cord-016871-1mlamf20	21	5	combat	combat	VB
cord-016871-1mlamf20	21	6	its	-PRON-	PRP$
cord-016871-1mlamf20	21	7	development	development	NN
cord-016871-1mlamf20	21	8	(	(	-LRB-
cord-016871-1mlamf20	21	9	or	or	CC
cord-016871-1mlamf20	21	10	at	at	IN
cord-016871-1mlamf20	21	11	least	least	JJS
cord-016871-1mlamf20	21	12	attenuate	attenuate	VB
cord-016871-1mlamf20	21	13	its	-PRON-	PRP$
cord-016871-1mlamf20	21	14	effects	effect	NNS
cord-016871-1mlamf20	21	15	)	)	-RRB-
cord-016871-1mlamf20	21	16	,	,	,
cord-016871-1mlamf20	21	17	several	several	JJ
cord-016871-1mlamf20	21	18	authors	author	NNS
cord-016871-1mlamf20	21	19	began	begin	VBD
cord-016871-1mlamf20	21	20	advocating	advocate	VBG
cord-016871-1mlamf20	21	21	for	for	IN
cord-016871-1mlamf20	21	22	Damage	damage	NN
cord-016871-1mlamf20	21	23	Control	Control	NNP
cord-016871-1mlamf20	21	24	Surgery	surgery	NN
cord-016871-1mlamf20	21	25	[	[	-LRB-
cord-016871-1mlamf20	21	26	1	1	CD
cord-016871-1mlamf20	21	27	,	,	,
cord-016871-1mlamf20	21	28	2	2	CD
cord-016871-1mlamf20	21	29	]	]	-RRB-
cord-016871-1mlamf20	21	30	.	.	.
cord-016871-1mlamf20	22	1	However	however	RB
cord-016871-1mlamf20	22	2	,	,	,
cord-016871-1mlamf20	22	3	the	the	DT
cord-016871-1mlamf20	22	4	principles	principle	NNS
cord-016871-1mlamf20	22	5	of	of	IN
cord-016871-1mlamf20	22	6	Damage	Damage	NNP
cord-016871-1mlamf20	22	7	Control	Control	NNP
cord-016871-1mlamf20	22	8	have	have	VBP
cord-016871-1mlamf20	22	9	spread	spread	VBN
cord-016871-1mlamf20	22	10	through	through	IN
cord-016871-1mlamf20	22	11	the	the	DT
cord-016871-1mlamf20	22	12	trauma	trauma	NN
cord-016871-1mlamf20	22	13	centers	center	NNS
cord-016871-1mlamf20	22	14	and	and	CC
cord-016871-1mlamf20	22	15	into	into	IN
cord-016871-1mlamf20	22	16	the	the	DT
cord-016871-1mlamf20	22	17	operating	operate	VBG
cord-016871-1mlamf20	22	18	theaters	theater	NNS
cord-016871-1mlamf20	22	19	and	and	CC
cord-016871-1mlamf20	22	20	intensive	intensive	JJ
cord-016871-1mlamf20	22	21	care	care	NN
cord-016871-1mlamf20	22	22	units	unit	NNS
cord-016871-1mlamf20	22	23	[	[	-LRB-
cord-016871-1mlamf20	22	24	3	3	CD
cord-016871-1mlamf20	22	25	]	]	-RRB-
cord-016871-1mlamf20	22	26	.	.	.
cord-016871-1mlamf20	23	1	Central	central	JJ
cord-016871-1mlamf20	23	2	to	to	IN
cord-016871-1mlamf20	23	3	this	this	DT
cord-016871-1mlamf20	23	4	concept	concept	NN
cord-016871-1mlamf20	23	5	is	be	VBZ
cord-016871-1mlamf20	23	6	aggressively	aggressively	RB
cord-016871-1mlamf20	23	7	and	and	CC
cord-016871-1mlamf20	23	8	rapidly	rapidly	RB
cord-016871-1mlamf20	23	9	addressing	address	VBG
cord-016871-1mlamf20	23	10	all	all	DT
cord-016871-1mlamf20	23	11	three	three	CD
cord-016871-1mlamf20	23	12	components	component	NNS
cord-016871-1mlamf20	23	13	simultaneously	simultaneously	RB
cord-016871-1mlamf20	23	14	,	,	,
cord-016871-1mlamf20	23	15	as	as	IN
cord-016871-1mlamf20	23	16	each	each	DT
cord-016871-1mlamf20	23	17	greatly	greatly	RB
cord-016871-1mlamf20	23	18	affects	affect	VBZ
cord-016871-1mlamf20	23	19	the	the	DT
cord-016871-1mlamf20	23	20	other	other	JJ
cord-016871-1mlamf20	23	21	.	.	.
cord-016871-1mlamf20	24	1	Hypothermia	hypothermia	NN
cord-016871-1mlamf20	24	2	,	,	,
cord-016871-1mlamf20	24	3	a	a	DT
cord-016871-1mlamf20	24	4	core	core	NN
cord-016871-1mlamf20	24	5	body	body	NN
cord-016871-1mlamf20	24	6	temperature	temperature	NN
cord-016871-1mlamf20	24	7	of	of	IN
cord-016871-1mlamf20	24	8	34	34	CD
cord-016871-1mlamf20	24	9	-	-	SYM
cord-016871-1mlamf20	24	10	36	36	CD
cord-016871-1mlamf20	24	11	°	°	NN
cord-016871-1mlamf20	24	12	C	c	NN
cord-016871-1mlamf20	24	13	,	,	,
cord-016871-1mlamf20	24	14	in	in	IN
cord-016871-1mlamf20	24	15	the	the	DT
cord-016871-1mlamf20	24	16	trauma	trauma	NN
cord-016871-1mlamf20	24	17	patient	patient	NN
cord-016871-1mlamf20	24	18	primarily	primarily	RB
cord-016871-1mlamf20	24	19	results	result	VBZ
cord-016871-1mlamf20	24	20	from	from	IN
cord-016871-1mlamf20	24	21	re	re	NNP
cord-016871-1mlamf20	24	22	fl	fl	NNP
cord-016871-1mlamf20	24	23	exive	exive	JJ
cord-016871-1mlamf20	24	24	peripheral	peripheral	JJ
cord-016871-1mlamf20	24	25	vasoconstriction	vasoconstriction	NN
cord-016871-1mlamf20	24	26	in	in	IN
cord-016871-1mlamf20	24	27	the	the	DT
cord-016871-1mlamf20	24	28	hypovolemic	hypovolemic	JJ
cord-016871-1mlamf20	24	29	patient	patient	NN
cord-016871-1mlamf20	24	30	.	.	.
cord-016871-1mlamf20	25	1	This	this	DT
cord-016871-1mlamf20	25	2	phenomenon	phenomenon	NN
cord-016871-1mlamf20	25	3	is	be	VBZ
cord-016871-1mlamf20	25	4	further	far	RBR
cord-016871-1mlamf20	25	5	exacerbated	exacerbate	VBN
cord-016871-1mlamf20	25	6	by	by	IN
cord-016871-1mlamf20	25	7	rapid	rapid	JJ
cord-016871-1mlamf20	25	8	infusion	infusion	NN
cord-016871-1mlamf20	25	9	of	of	IN
cord-016871-1mlamf20	25	10	unwarmed	unwarmed	NNP
cord-016871-1mlamf20	25	11	crystalloid	crystalloid	NNP
cord-016871-1mlamf20	25	12	fl	fl	NNP
cord-016871-1mlamf20	25	13	uid	uid	NN
cord-016871-1mlamf20	25	14	during	during	IN
cord-016871-1mlamf20	25	15	initial	initial	JJ
cord-016871-1mlamf20	25	16	resuscitation	resuscitation	NN
cord-016871-1mlamf20	25	17	.	.	.
cord-016871-1mlamf20	26	1	This	this	DT
cord-016871-1mlamf20	26	2	condition	condition	NN
cord-016871-1mlamf20	26	3	impairs	impair	VBZ
cord-016871-1mlamf20	26	4	coagulation	coagulation	NN
cord-016871-1mlamf20	26	5	factor	factor	NN
cord-016871-1mlamf20	26	6	activity	activity	NN
cord-016871-1mlamf20	26	7	and	and	CC
cord-016871-1mlamf20	26	8	platelet	platelet	NN
cord-016871-1mlamf20	26	9	function	function	NN
cord-016871-1mlamf20	26	10	,	,	,
cord-016871-1mlamf20	26	11	such	such	JJ
cord-016871-1mlamf20	26	12	as	as	IN
cord-016871-1mlamf20	26	13	their	-PRON-	PRP$
cord-016871-1mlamf20	26	14	ability	ability	NN
cord-016871-1mlamf20	26	15	to	to	TO
cord-016871-1mlamf20	26	16	produce	produce	VB
cord-016871-1mlamf20	26	17	thromboxane	thromboxane	NN
cord-016871-1mlamf20	26	18	,	,	,
cord-016871-1mlamf20	26	19	and	and	CC
cord-016871-1mlamf20	26	20	must	must	MD
cord-016871-1mlamf20	26	21	be	be	VB
cord-016871-1mlamf20	26	22	rapidly	rapidly	RB
cord-016871-1mlamf20	26	23	reversed	reverse	VBN
cord-016871-1mlamf20	26	24	[	[	-LRB-
cord-016871-1mlamf20	26	25	4	4	CD
cord-016871-1mlamf20	26	26	]	]	-RRB-
cord-016871-1mlamf20	26	27	.	.	.
cord-016871-1mlamf20	27	1	Crystalloid	Crystalloid	NNP
cord-016871-1mlamf20	27	2	and	and	CC
cord-016871-1mlamf20	27	3	colloid	colloid	NN
cord-016871-1mlamf20	27	4	fl	fl	NNP
cord-016871-1mlamf20	27	5	uids	uid	NNS
cord-016871-1mlamf20	27	6	also	also	RB
cord-016871-1mlamf20	27	7	contribute	contribute	VBP
cord-016871-1mlamf20	27	8	to	to	IN
cord-016871-1mlamf20	27	9	hemodilution	hemodilution	NN
cord-016871-1mlamf20	27	10	of	of	IN
cord-016871-1mlamf20	27	11	clotting	clotting	NN
cord-016871-1mlamf20	27	12	factors	factor	NNS
cord-016871-1mlamf20	27	13	,	,	,
cord-016871-1mlamf20	27	14	further	further	RB
cord-016871-1mlamf20	27	15	promoting	promote	VBG
cord-016871-1mlamf20	27	16	ongoing	ongoing	JJ
cord-016871-1mlamf20	27	17	bleeding	bleeding	NN
cord-016871-1mlamf20	27	18	.	.	.
cord-016871-1mlamf20	28	1	Hence	hence	RB
cord-016871-1mlamf20	28	2	,	,	,
cord-016871-1mlamf20	28	3	in	in	IN
cord-016871-1mlamf20	28	4	this	this	DT
cord-016871-1mlamf20	28	5	situation	situation	NN
cord-016871-1mlamf20	28	6	,	,	,
cord-016871-1mlamf20	28	7	early	early	JJ
cord-016871-1mlamf20	28	8	plasma	plasma	NN
cord-016871-1mlamf20	28	9	therapy	therapy	NN
cord-016871-1mlamf20	28	10	and	and	CC
cord-016871-1mlamf20	28	11	platelets	platelet	NNS
cord-016871-1mlamf20	28	12	have	have	VBP
cord-016871-1mlamf20	28	13	been	be	VBN
cord-016871-1mlamf20	28	14	shown	show	VBN
cord-016871-1mlamf20	28	15	to	to	TO
cord-016871-1mlamf20	28	16	improve	improve	VB
cord-016871-1mlamf20	28	17	outcomes	outcome	NNS
cord-016871-1mlamf20	28	18	[	[	-LRB-
cord-016871-1mlamf20	28	19	5	5	CD
cord-016871-1mlamf20	28	20	]	]	-RRB-
cord-016871-1mlamf20	28	21	.	.	.
cord-016871-1mlamf20	29	1	Acidosis	acidosis	NN
cord-016871-1mlamf20	29	2	has	have	VBZ
cord-016871-1mlamf20	29	3	been	be	VBN
cord-016871-1mlamf20	29	4	hypothesized	hypothesize	VBN
cord-016871-1mlamf20	29	5	to	to	TO
cord-016871-1mlamf20	29	6	result	result	VB
cord-016871-1mlamf20	29	7	from	from	IN
cord-016871-1mlamf20	29	8	hypoperfusion	hypoperfusion	NN
cord-016871-1mlamf20	29	9	and	and	CC
cord-016871-1mlamf20	29	10	excess	excess	JJ
cord-016871-1mlamf20	29	11	administration	administration	NN
cord-016871-1mlamf20	29	12	of	of	IN
cord-016871-1mlamf20	29	13	ionic	ionic	JJ
cord-016871-1mlamf20	29	14	chloride	chloride	NN
cord-016871-1mlamf20	29	15	in	in	IN
cord-016871-1mlamf20	29	16	normal	normal	JJ
cord-016871-1mlamf20	29	17	saline	saline	NN
cord-016871-1mlamf20	29	18	administration	administration	NN
cord-016871-1mlamf20	29	19	.	.	.
cord-016871-1mlamf20	30	1	The	the	DT
cord-016871-1mlamf20	30	2	acidosis	acidosis	NN
cord-016871-1mlamf20	30	3	disturbs	disturb	VBZ
cord-016871-1mlamf20	30	4	platelet	platelet	NN
cord-016871-1mlamf20	30	5	function	function	NN
cord-016871-1mlamf20	30	6	and	and	CC
cord-016871-1mlamf20	30	7	morphology	morphology	NN
cord-016871-1mlamf20	30	8	,	,	,
cord-016871-1mlamf20	30	9	reduces	reduce	VBZ
cord-016871-1mlamf20	30	10	coagulation	coagulation	NN
cord-016871-1mlamf20	30	11	factor	factor	NN
cord-016871-1mlamf20	30	12	complex	complex	JJ
cord-016871-1mlamf20	30	13	activity	activity	NN
cord-016871-1mlamf20	30	14	,	,	,
cord-016871-1mlamf20	30	15	and	and	CC
cord-016871-1mlamf20	30	16	degrades	degrade	VBZ
cord-016871-1mlamf20	30	17	fi	fi	NNP
cord-016871-1mlamf20	30	18	brinogen	brinogen	NNP
cord-016871-1mlamf20	30	19	.	.	.
cord-016871-1mlamf20	31	1	Approximately	approximately	RB
cord-016871-1mlamf20	31	2	25	25	CD
cord-016871-1mlamf20	31	3	%	%	NN
cord-016871-1mlamf20	31	4	of	of	IN
cord-016871-1mlamf20	31	5	trauma	trauma	NN
cord-016871-1mlamf20	31	6	patients	patient	NNS
cord-016871-1mlamf20	31	7	present	present	JJ
cord-016871-1mlamf20	31	8	with	with	IN
cord-016871-1mlamf20	31	9	abnormal	abnormal	JJ
cord-016871-1mlamf20	31	10	coagulation	coagulation	NN
cord-016871-1mlamf20	31	11	parameters	parameter	NNS
cord-016871-1mlamf20	31	12	,	,	,
cord-016871-1mlamf20	31	13	and	and	CC
cord-016871-1mlamf20	31	14	these	these	DT
cord-016871-1mlamf20	31	15	have	have	VBP
cord-016871-1mlamf20	31	16	been	be	VBN
cord-016871-1mlamf20	31	17	associated	associate	VBN
cord-016871-1mlamf20	31	18	with	with	IN
cord-016871-1mlamf20	31	19	poorer	poor	JJR
cord-016871-1mlamf20	31	20	outcomes	outcome	NNS
cord-016871-1mlamf20	31	21	in	in	IN
cord-016871-1mlamf20	31	22	these	these	DT
cord-016871-1mlamf20	31	23	patients	patient	NNS
cord-016871-1mlamf20	31	24	.	.	.
cord-016871-1mlamf20	32	1	The	the	DT
cord-016871-1mlamf20	32	2	three	three	CD
cord-016871-1mlamf20	32	3	conditions	condition	NNS
cord-016871-1mlamf20	32	4	previously	previously	RB
cord-016871-1mlamf20	32	5	mentioned	mention	VBD
cord-016871-1mlamf20	32	6	contribute	contribute	VBP
cord-016871-1mlamf20	32	7	to	to	IN
cord-016871-1mlamf20	32	8	poor	poor	JJ
cord-016871-1mlamf20	32	9	clot	clot	NN
cord-016871-1mlamf20	32	10	formation	formation	NN
cord-016871-1mlamf20	32	11	and	and	CC
cord-016871-1mlamf20	32	12	aggravated	aggravated	JJ
cord-016871-1mlamf20	32	13	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	32	14	[	[	-LRB-
cord-016871-1mlamf20	32	15	4	4	CD
cord-016871-1mlamf20	32	16	]	]	-RRB-
cord-016871-1mlamf20	32	17	.	.	.
cord-016871-1mlamf20	33	1	Evidence	evidence	NN
cord-016871-1mlamf20	33	2	exists	exist	VBZ
cord-016871-1mlamf20	33	3	supporting	support	VBG
cord-016871-1mlamf20	33	4	increased	increase	VBN
cord-016871-1mlamf20	33	5	survival	survival	NN
cord-016871-1mlamf20	33	6	upon	upon	IN
cord-016871-1mlamf20	33	7	rapid	rapid	JJ
cord-016871-1mlamf20	33	8	treatment	treatment	NN
cord-016871-1mlamf20	33	9	of	of	IN
cord-016871-1mlamf20	33	10	initial	initial	JJ
cord-016871-1mlamf20	33	11	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	33	12	[	[	-LRB-
cord-016871-1mlamf20	33	13	5	5	CD
cord-016871-1mlamf20	33	14	,	,	,
cord-016871-1mlamf20	33	15	6	6	CD
cord-016871-1mlamf20	33	16	]	]	-RRB-
cord-016871-1mlamf20	33	17	.	.	.
cord-016871-1mlamf20	34	1	Preemptive	preemptive	JJ
cord-016871-1mlamf20	34	2	strategies	strategy	NNS
cord-016871-1mlamf20	34	3	have	have	VBP
cord-016871-1mlamf20	34	4	been	be	VBN
cord-016871-1mlamf20	34	5	shown	show	VBN
cord-016871-1mlamf20	34	6	to	to	TO
cord-016871-1mlamf20	34	7	actually	actually	RB
cord-016871-1mlamf20	34	8	reduce	reduce	VB
cord-016871-1mlamf20	34	9	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	34	10	and	and	CC
cord-016871-1mlamf20	34	11	the	the	DT
cord-016871-1mlamf20	34	12	number	number	NN
cord-016871-1mlamf20	34	13	of	of	IN
cord-016871-1mlamf20	34	14	overall	overall	JJ
cord-016871-1mlamf20	34	15	transfusions	transfusion	NNS
cord-016871-1mlamf20	34	16	required	require	VBN
cord-016871-1mlamf20	34	17	to	to	TO
cord-016871-1mlamf20	34	18	treat	treat	VB
cord-016871-1mlamf20	34	19	the	the	DT
cord-016871-1mlamf20	34	20	patient	patient	NN
cord-016871-1mlamf20	34	21	[	[	-LRB-
cord-016871-1mlamf20	34	22	7	7	CD
cord-016871-1mlamf20	34	23	,	,	,
cord-016871-1mlamf20	34	24	8	8	CD
cord-016871-1mlamf20	34	25	]	]	-RRB-
cord-016871-1mlamf20	34	26	.	.	.
cord-016871-1mlamf20	35	1	However	however	RB
cord-016871-1mlamf20	35	2	,	,	,
cord-016871-1mlamf20	35	3	challenges	challenge	NNS
cord-016871-1mlamf20	35	4	to	to	IN
cord-016871-1mlamf20	35	5	implementation	implementation	NN
cord-016871-1mlamf20	35	6	include	include	VBP
cord-016871-1mlamf20	35	7	time	time	NN
cord-016871-1mlamf20	35	8	limitations	limitation	NNS
cord-016871-1mlamf20	35	9	of	of	IN
cord-016871-1mlamf20	35	10	laboratory	laboratory	NN
cord-016871-1mlamf20	35	11	-	-	HYPH
cord-016871-1mlamf20	35	12	guided	guide	VBN
cord-016871-1mlamf20	35	13	component	component	NN
cord-016871-1mlamf20	35	14	therapy	therapy	NN
cord-016871-1mlamf20	35	15	since	since	IN
cord-016871-1mlamf20	35	16	the	the	DT
cord-016871-1mlamf20	35	17	results	result	NNS
cord-016871-1mlamf20	35	18	of	of	IN
cord-016871-1mlamf20	35	19	the	the	DT
cord-016871-1mlamf20	35	20	tests	test	NNS
cord-016871-1mlamf20	35	21	are	be	VBP
cord-016871-1mlamf20	35	22	not	not	RB
cord-016871-1mlamf20	35	23	immediate	immediate	JJ
cord-016871-1mlamf20	35	24	.	.	.
cord-016871-1mlamf20	36	1	Another	another	DT
cord-016871-1mlamf20	36	2	dif	dif	NN
cord-016871-1mlamf20	36	3	fi	fi	FW
cord-016871-1mlamf20	36	4	culty	culty	FW
cord-016871-1mlamf20	36	5	is	be	VBZ
cord-016871-1mlamf20	36	6	that	that	IN
cord-016871-1mlamf20	36	7	once	once	IN
cord-016871-1mlamf20	36	8	it	-PRON-	PRP
cord-016871-1mlamf20	36	9	has	have	VBZ
cord-016871-1mlamf20	36	10	been	be	VBN
cord-016871-1mlamf20	36	11	determined	determine	VBN
cord-016871-1mlamf20	36	12	that	that	IN
cord-016871-1mlamf20	36	13	the	the	DT
cord-016871-1mlamf20	36	14	patient	patient	NN
cord-016871-1mlamf20	36	15	should	should	MD
cord-016871-1mlamf20	36	16	receive	receive	VB
cord-016871-1mlamf20	36	17	plasma	plasma	NN
cord-016871-1mlamf20	36	18	,	,	,
cord-016871-1mlamf20	36	19	it	-PRON-	PRP
cord-016871-1mlamf20	36	20	may	may	MD
cord-016871-1mlamf20	36	21	take	take	VB
cord-016871-1mlamf20	36	22	another	another	DT
cord-016871-1mlamf20	36	23	30	30	CD
cord-016871-1mlamf20	36	24	-	-	SYM
cord-016871-1mlamf20	36	25	45	45	CD
cord-016871-1mlamf20	36	26	min	min	NN
cord-016871-1mlamf20	36	27	to	to	TO
cord-016871-1mlamf20	36	28	thaw	thaw	VB
cord-016871-1mlamf20	36	29	and	and	CC
cord-016871-1mlamf20	36	30	deliver	deliver	VB
cord-016871-1mlamf20	36	31	the	the	DT
cord-016871-1mlamf20	36	32	products	product	NNS
cord-016871-1mlamf20	36	33	[	[	-LRB-
cord-016871-1mlamf20	36	34	5	5	CD
cord-016871-1mlamf20	36	35	]	]	-RRB-
cord-016871-1mlamf20	36	36	.	.	.
cord-016871-1mlamf20	37	1	As	as	IN
cord-016871-1mlamf20	37	2	such	such	JJ
cord-016871-1mlamf20	37	3	,	,	,
cord-016871-1mlamf20	37	4	hospitals	hospital	NNS
cord-016871-1mlamf20	37	5	should	should	MD
cord-016871-1mlamf20	37	6	have	have	VB
cord-016871-1mlamf20	37	7	in	in	IN
cord-016871-1mlamf20	37	8	place	place	NN
cord-016871-1mlamf20	37	9	a	a	DT
cord-016871-1mlamf20	37	10	thawed	thaw	VBN
cord-016871-1mlamf20	37	11	plasma	plasma	NN
cord-016871-1mlamf20	37	12	program	program	NN
cord-016871-1mlamf20	37	13	,	,	,
cord-016871-1mlamf20	37	14	keeping	keep	VBG
cord-016871-1mlamf20	37	15	adequate	adequate	JJ
cord-016871-1mlamf20	37	16	numbers	number	NNS
cord-016871-1mlamf20	37	17	of	of	IN
cord-016871-1mlamf20	38	1	"	"	``
cord-016871-1mlamf20	38	2	universal	universal	JJ
cord-016871-1mlamf20	38	3	"	"	''
cord-016871-1mlamf20	38	4	and	and	CC
cord-016871-1mlamf20	38	5	type	type	NN
cord-016871-1mlamf20	38	6	-	-	HYPH
cord-016871-1mlamf20	38	7	speci	speci	FW
cord-016871-1mlamf20	38	8	fi	fi	NN
cord-016871-1mlamf20	38	9	c	c	NN
cord-016871-1mlamf20	38	10	thawed	thaw	VBD
cord-016871-1mlamf20	38	11	plasma	plasma	NN
cord-016871-1mlamf20	38	12	available	available	JJ
cord-016871-1mlamf20	38	13	for	for	IN
cord-016871-1mlamf20	38	14	immediate	immediate	JJ
cord-016871-1mlamf20	38	15	release	release	NN
cord-016871-1mlamf20	38	16	.	.	.
cord-016871-1mlamf20	39	1	Plasma	plasma	NN
cord-016871-1mlamf20	39	2	thawing	thawing	NN
cord-016871-1mlamf20	39	3	protocols	protocol	NNS
cord-016871-1mlamf20	39	4	exist	exist	VBP
cord-016871-1mlamf20	39	5	to	to	TO
cord-016871-1mlamf20	39	6	avoid	avoid	VB
cord-016871-1mlamf20	39	7	this	this	DT
cord-016871-1mlamf20	39	8	issue	issue	NN
cord-016871-1mlamf20	39	9	and	and	CC
cord-016871-1mlamf20	39	10	are	be	VBP
cord-016871-1mlamf20	39	11	discussed	discuss	VBN
cord-016871-1mlamf20	39	12	in	in	IN
cord-016871-1mlamf20	39	13	later	later	JJ
cord-016871-1mlamf20	39	14	sections	section	NNS
cord-016871-1mlamf20	39	15	.	.	.
cord-016871-1mlamf20	40	1	In	in	IN
cord-016871-1mlamf20	40	2	acutely	acutely	RB
cord-016871-1mlamf20	40	3	bleeding	bleed	VBG
cord-016871-1mlamf20	40	4	patients	patient	NNS
cord-016871-1mlamf20	40	5	,	,	,
cord-016871-1mlamf20	40	6	massive	massive	JJ
cord-016871-1mlamf20	40	7	transfusion	transfusion	NN
cord-016871-1mlamf20	40	8	protocols	protocol	NNS
cord-016871-1mlamf20	40	9	are	be	VBP
cord-016871-1mlamf20	40	10	often	often	RB
cord-016871-1mlamf20	40	11	activated	activate	VBN
cord-016871-1mlamf20	40	12	in	in	IN
cord-016871-1mlamf20	40	13	order	order	NN
cord-016871-1mlamf20	40	14	to	to	IN
cord-016871-1mlamf20	40	15	ef	ef	NNP
cord-016871-1mlamf20	40	16	fi	fi	NNP
cord-016871-1mlamf20	40	17	caciously	caciously	RB
cord-016871-1mlamf20	40	18	restore	restore	VB
cord-016871-1mlamf20	40	19	blood	blood	NN
cord-016871-1mlamf20	40	20	volume	volume	NN
cord-016871-1mlamf20	40	21	and	and	CC
cord-016871-1mlamf20	40	22	hemostasis	hemostasis	NN
cord-016871-1mlamf20	40	23	and	and	CC
cord-016871-1mlamf20	40	24	thawed	thawed	JJ
cord-016871-1mlamf20	40	25	plasma	plasma	NN
cord-016871-1mlamf20	40	26	is	be	VBZ
cord-016871-1mlamf20	40	27	critical	critical	JJ
cord-016871-1mlamf20	40	28	to	to	IN
cord-016871-1mlamf20	40	29	their	-PRON-	PRP$
cord-016871-1mlamf20	40	30	success	success	NN
cord-016871-1mlamf20	40	31	[	[	-LRB-
cord-016871-1mlamf20	40	32	5	5	CD
cord-016871-1mlamf20	40	33	,	,	,
cord-016871-1mlamf20	40	34	6	6	CD
cord-016871-1mlamf20	40	35	]	]	-RRB-
cord-016871-1mlamf20	40	36	.	.	.
cord-016871-1mlamf20	41	1	A	a	DT
cord-016871-1mlamf20	41	2	massive	massive	JJ
cord-016871-1mlamf20	41	3	transfusion	transfusion	NN
cord-016871-1mlamf20	41	4	(	(	-LRB-
cord-016871-1mlamf20	41	5	MT	MT	NNP
cord-016871-1mlamf20	41	6	)	)	-RRB-
cord-016871-1mlamf20	41	7	is	be	VBZ
cord-016871-1mlamf20	41	8	de	de	FW
cord-016871-1mlamf20	41	9	fi	fi	NNP
cord-016871-1mlamf20	41	10	ned	ned	NNP
cord-016871-1mlamf20	41	11	as	as	IN
cord-016871-1mlamf20	41	12	more	more	JJR
cord-016871-1mlamf20	41	13	than	than	IN
cord-016871-1mlamf20	41	14	ten	ten	CD
cord-016871-1mlamf20	41	15	units	unit	NNS
cord-016871-1mlamf20	41	16	of	of	IN
cord-016871-1mlamf20	41	17	red	red	JJ
cord-016871-1mlamf20	41	18	blood	blood	NN
cord-016871-1mlamf20	41	19	cells	cell	NNS
cord-016871-1mlamf20	41	20	(	(	-LRB-
cord-016871-1mlamf20	41	21	RBC	RBC	NNP
cord-016871-1mlamf20	41	22	)	)	-RRB-
cord-016871-1mlamf20	41	23	in	in	IN
cord-016871-1mlamf20	41	24	24	24	CD
cord-016871-1mlamf20	41	25	h	h	NN
cord-016871-1mlamf20	41	26	[	[	-LRB-
cord-016871-1mlamf20	41	27	5	5	CD
cord-016871-1mlamf20	41	28	]	]	-RRB-
cord-016871-1mlamf20	41	29	.	.	.
cord-016871-1mlamf20	42	1	A	a	DT
cord-016871-1mlamf20	42	2	massive	massive	JJ
cord-016871-1mlamf20	42	3	transfusion	transfusion	NN
cord-016871-1mlamf20	42	4	protocol	protocol	NN
cord-016871-1mlamf20	42	5	(	(	-LRB-
cord-016871-1mlamf20	42	6	MTP	MTP	NNP
cord-016871-1mlamf20	42	7	)	)	-RRB-
cord-016871-1mlamf20	42	8	is	be	VBZ
cord-016871-1mlamf20	42	9	the	the	DT
cord-016871-1mlamf20	42	10	standardization	standardization	NN
cord-016871-1mlamf20	42	11	of	of	IN
cord-016871-1mlamf20	42	12	the	the	DT
cord-016871-1mlamf20	42	13	delivery	delivery	NN
cord-016871-1mlamf20	42	14	and	and	CC
cord-016871-1mlamf20	42	15	transfusion	transfusion	NN
cord-016871-1mlamf20	42	16	of	of	IN
cord-016871-1mlamf20	42	17	RBC	RBC	NNP
cord-016871-1mlamf20	42	18	,	,	,
cord-016871-1mlamf20	42	19	plasma	plasma	NN
cord-016871-1mlamf20	42	20	,	,	,
cord-016871-1mlamf20	42	21	and	and	CC
cord-016871-1mlamf20	42	22	platelets	platelet	NNS
cord-016871-1mlamf20	42	23	in	in	IN
cord-016871-1mlamf20	42	24	predetermined	predetermined	JJ
cord-016871-1mlamf20	42	25	and	and	CC
cord-016871-1mlamf20	42	26	prede	prede	NN
cord-016871-1mlamf20	42	27	fi	fi	NN
cord-016871-1mlamf20	42	28	ned	ned	NNP
cord-016871-1mlamf20	42	29	ratios	ratio	NNS
cord-016871-1mlamf20	42	30	as	as	IN
cord-016871-1mlamf20	42	31	facilitated	facilitate	VBN
cord-016871-1mlamf20	42	32	by	by	IN
cord-016871-1mlamf20	42	33	a	a	DT
cord-016871-1mlamf20	42	34	surgical	surgical	JJ
cord-016871-1mlamf20	42	35	or	or	CC
cord-016871-1mlamf20	42	36	medical	medical	JJ
cord-016871-1mlamf20	42	37	team	team	NN
cord-016871-1mlamf20	42	38	.	.	.
cord-016871-1mlamf20	43	1	In	in	IN
cord-016871-1mlamf20	43	2	the	the	DT
cord-016871-1mlamf20	43	3	patient	patient	NN
cord-016871-1mlamf20	43	4	requiring	require	VBG
cord-016871-1mlamf20	43	5	immediate	immediate	JJ
cord-016871-1mlamf20	43	6	resuscitation	resuscitation	NN
cord-016871-1mlamf20	43	7	,	,	,
cord-016871-1mlamf20	43	8	a	a	DT
cord-016871-1mlamf20	43	9	typical	typical	JJ
cord-016871-1mlamf20	43	10	MTP	MTP	NNP
cord-016871-1mlamf20	43	11	will	will	MD
cord-016871-1mlamf20	43	12	call	call	VB
cord-016871-1mlamf20	43	13	for	for	IN
cord-016871-1mlamf20	43	14	six	six	CD
cord-016871-1mlamf20	43	15	to	to	TO
cord-016871-1mlamf20	43	16	ten	ten	CD
cord-016871-1mlamf20	43	17	units	unit	NNS
cord-016871-1mlamf20	43	18	of	of	IN
cord-016871-1mlamf20	43	19	RBC	RBC	NNP
cord-016871-1mlamf20	43	20	,	,	,
cord-016871-1mlamf20	43	21	with	with	IN
cord-016871-1mlamf20	43	22	a	a	DT
cord-016871-1mlamf20	43	23	ratio	ratio	NN
cord-016871-1mlamf20	43	24	of	of	IN
cord-016871-1mlamf20	43	25	RBC	RBC	NNP
cord-016871-1mlamf20	43	26	to	to	IN
cord-016871-1mlamf20	43	27	plasma	plasma	NN
cord-016871-1mlamf20	43	28	and	and	CC
cord-016871-1mlamf20	43	29	platelets	platelet	NNS
cord-016871-1mlamf20	43	30	in	in	IN
cord-016871-1mlamf20	43	31	1:1:1	1:1:1	CD
cord-016871-1mlamf20	43	32	to	to	IN
cord-016871-1mlamf20	43	33	1:1:2	1:1:2	CD
cord-016871-1mlamf20	43	34	fashion	fashion	NN
cord-016871-1mlamf20	43	35	.	.	.
cord-016871-1mlamf20	44	1	This	this	DT
cord-016871-1mlamf20	44	2	protocol	protocol	NN
cord-016871-1mlamf20	44	3	and	and	CC
cord-016871-1mlamf20	44	4	release	release	NN
cord-016871-1mlamf20	44	5	of	of	IN
cord-016871-1mlamf20	44	6	products	product	NNS
cord-016871-1mlamf20	44	7	will	will	MD
cord-016871-1mlamf20	44	8	continue	continue	VB
cord-016871-1mlamf20	44	9	based	base	VBN
cord-016871-1mlamf20	44	10	on	on	IN
cord-016871-1mlamf20	44	11	ongoing	ongoing	JJ
cord-016871-1mlamf20	44	12	bleeding	bleeding	NN
cord-016871-1mlamf20	44	13	(	(	-LRB-
cord-016871-1mlamf20	44	14	Fig	Fig	NNP
cord-016871-1mlamf20	44	15	.	.	.
cord-016871-1mlamf20	44	16	12.1	12.1	CD
cord-016871-1mlamf20	44	17	)	)	-RRB-
cord-016871-1mlamf20	44	18	.	.	.
cord-016871-1mlamf20	45	1	These	these	DT
cord-016871-1mlamf20	45	2	assessments	assessment	NNS
cord-016871-1mlamf20	45	3	are	be	VBP
cord-016871-1mlamf20	45	4	generally	generally	RB
cord-016871-1mlamf20	45	5	implemented	implement	VBN
cord-016871-1mlamf20	45	6	"	"	``
cord-016871-1mlamf20	45	7	blind	blind	JJ
cord-016871-1mlamf20	45	8	,	,	,
cord-016871-1mlamf20	45	9	"	"	''
cord-016871-1mlamf20	45	10	with	with	IN
cord-016871-1mlamf20	45	11	subsequent	subsequent	JJ
cord-016871-1mlamf20	45	12	releases	release	NNS
cord-016871-1mlamf20	45	13	guided	guide	VBN
cord-016871-1mlamf20	45	14	by	by	IN
cord-016871-1mlamf20	45	15	routine	routine	JJ
cord-016871-1mlamf20	45	16	coagulation	coagulation	NN
cord-016871-1mlamf20	45	17	laboratory	laboratory	NN
cord-016871-1mlamf20	45	18	studies	study	NNS
cord-016871-1mlamf20	45	19	as	as	RB
cord-016871-1mlamf20	45	20	well	well	RB
cord-016871-1mlamf20	45	21	as	as	IN
cord-016871-1mlamf20	45	22	thromboelastography	thromboelastography	NNP
cord-016871-1mlamf20	45	23	(	(	-LRB-
cord-016871-1mlamf20	45	24	TEG	TEG	NNP
cord-016871-1mlamf20	45	25	)	)	-RRB-
cord-016871-1mlamf20	45	26	[	[	-LRB-
cord-016871-1mlamf20	45	27	9	9	CD
cord-016871-1mlamf20	45	28	]	]	-RRB-
cord-016871-1mlamf20	45	29	.	.	.
cord-016871-1mlamf20	46	1	Even	even	RB
cord-016871-1mlamf20	46	2	before	before	IN
cord-016871-1mlamf20	46	3	the	the	DT
cord-016871-1mlamf20	46	4	transfusions	transfusion	NNS
cord-016871-1mlamf20	46	5	take	take	VBP
cord-016871-1mlamf20	46	6	place	place	NN
cord-016871-1mlamf20	46	7	,	,	,
cord-016871-1mlamf20	46	8	MTPs	mtp	NNS
cord-016871-1mlamf20	46	9	call	call	VB
cord-016871-1mlamf20	46	10	for	for	IN
cord-016871-1mlamf20	46	11	the	the	DT
cord-016871-1mlamf20	46	12	rapid	rapid	JJ
cord-016871-1mlamf20	46	13	mobilization	mobilization	NN
cord-016871-1mlamf20	46	14	of	of	IN
cord-016871-1mlamf20	46	15	blood	blood	NN
cord-016871-1mlamf20	46	16	components	component	NNS
cord-016871-1mlamf20	46	17	by	by	IN
cord-016871-1mlamf20	46	18	having	have	VBG
cord-016871-1mlamf20	46	19	AB	AB	NNP
cord-016871-1mlamf20	46	20	thawed	thaw	VBN
cord-016871-1mlamf20	46	21	plasma	plasma	NN
cord-016871-1mlamf20	46	22	and	and	CC
cord-016871-1mlamf20	46	23	group	group	NN
cord-016871-1mlamf20	47	1	O	o	UH
cord-016871-1mlamf20	47	2	RBC	RBC	NNP
cord-016871-1mlamf20	47	3	[	[	-LRB-
cord-016871-1mlamf20	47	4	10	10	CD
cord-016871-1mlamf20	47	5	]	]	-RRB-
cord-016871-1mlamf20	47	6	.	.	.
cord-016871-1mlamf20	48	1	A	a	DT
cord-016871-1mlamf20	48	2	type	type	NN
cord-016871-1mlamf20	48	3	and	and	CC
cord-016871-1mlamf20	48	4	screen	screen	NN
cord-016871-1mlamf20	48	5	should	should	MD
cord-016871-1mlamf20	48	6	be	be	VB
cord-016871-1mlamf20	48	7	drawn	draw	VBN
cord-016871-1mlamf20	48	8	as	as	RB
cord-016871-1mlamf20	48	9	soon	soon	RB
cord-016871-1mlamf20	48	10	as	as	IN
cord-016871-1mlamf20	48	11	possible	possible	JJ
cord-016871-1mlamf20	48	12	to	to	TO
cord-016871-1mlamf20	48	13	allow	allow	VB
cord-016871-1mlamf20	48	14	for	for	IN
cord-016871-1mlamf20	48	15	the	the	DT
cord-016871-1mlamf20	48	16	transition	transition	NN
cord-016871-1mlamf20	48	17	from	from	IN
cord-016871-1mlamf20	48	18	universal	universal	JJ
cord-016871-1mlamf20	48	19	products	product	NNS
cord-016871-1mlamf20	48	20	to	to	IN
cord-016871-1mlamf20	48	21	type	type	NN
cord-016871-1mlamf20	48	22	-	-	HYPH
cord-016871-1mlamf20	48	23	speci	speci	FW
cord-016871-1mlamf20	48	24	fi	fi	NN
cord-016871-1mlamf20	48	25	c	c	NN
cord-016871-1mlamf20	48	26	ones	one	NNS
cord-016871-1mlamf20	48	27	.	.	.
cord-016871-1mlamf20	49	1	The	the	DT
cord-016871-1mlamf20	49	2	ef	ef	NNP
cord-016871-1mlamf20	49	3	fi	fi	NN
cord-016871-1mlamf20	49	4	cacy	cacy	NN
cord-016871-1mlamf20	49	5	of	of	IN
cord-016871-1mlamf20	49	6	an	an	DT
cord-016871-1mlamf20	49	7	MTP	MTP	NNP
cord-016871-1mlamf20	49	8	also	also	RB
cord-016871-1mlamf20	49	9	lies	lie	VBZ
cord-016871-1mlamf20	49	10	in	in	IN
cord-016871-1mlamf20	49	11	its	-PRON-	PRP$
cord-016871-1mlamf20	49	12	early	early	JJ
cord-016871-1mlamf20	49	13	implementation	implementation	NN
cord-016871-1mlamf20	49	14	as	as	RB
cord-016871-1mlamf20	49	15	well	well	RB
cord-016871-1mlamf20	49	16	as	as	IN
cord-016871-1mlamf20	49	17	identi	identi	NNP
cord-016871-1mlamf20	49	18	fi	fi	NNP
cord-016871-1mlamf20	49	19	cation	cation	NNP
cord-016871-1mlamf20	49	20	of	of	IN
cord-016871-1mlamf20	49	21	patients	patient	NNS
cord-016871-1mlamf20	49	22	who	who	WP
cord-016871-1mlamf20	49	23	would	would	MD
cord-016871-1mlamf20	49	24	bene	bene	VB
cord-016871-1mlamf20	49	25	fi	fi	VB
cord-016871-1mlamf20	49	26	t	t	NN
cord-016871-1mlamf20	49	27	from	from	IN
cord-016871-1mlamf20	49	28	such	such	PDT
cord-016871-1mlamf20	49	29	an	an	DT
cord-016871-1mlamf20	49	30	intervention	intervention	NN
cord-016871-1mlamf20	49	31	.	.	.
cord-016871-1mlamf20	50	1	Criteria	criterion	NNS
cord-016871-1mlamf20	50	2	for	for	IN
cord-016871-1mlamf20	50	3	activation	activation	NN
cord-016871-1mlamf20	50	4	include	include	VBP
cord-016871-1mlamf20	50	5	laboratory	laboratory	NN
cord-016871-1mlamf20	50	6	values	value	NNS
cord-016871-1mlamf20	50	7	,	,	,
cord-016871-1mlamf20	50	8	anatomic	anatomic	JJ
cord-016871-1mlamf20	50	9	injuries	injury	NNS
cord-016871-1mlamf20	50	10	,	,	,
cord-016871-1mlamf20	50	11	and	and	CC
cord-016871-1mlamf20	50	12	mechanism	mechanism	NN
cord-016871-1mlamf20	50	13	of	of	IN
cord-016871-1mlamf20	50	14	injury	injury	NN
cord-016871-1mlamf20	50	15	.	.	.
cord-016871-1mlamf20	51	1	Several	several	JJ
cord-016871-1mlamf20	51	2	authors	author	NNS
cord-016871-1mlamf20	51	3	have	have	VBP
cord-016871-1mlamf20	51	4	demonstrated	demonstrate	VBN
cord-016871-1mlamf20	51	5	that	that	IN
cord-016871-1mlamf20	51	6	the	the	DT
cord-016871-1mlamf20	51	7	transfusion	transfusion	NN
cord-016871-1mlamf20	51	8	of	of	IN
cord-016871-1mlamf20	51	9	uncross	uncross	VB
cord-016871-1mlamf20	51	10	-	-	HYPH
cord-016871-1mlamf20	51	11	matched	match	VBN
cord-016871-1mlamf20	51	12	RBCs	rbc	NNS
cord-016871-1mlamf20	51	13	is	be	VBZ
cord-016871-1mlamf20	51	14	an	an	DT
cord-016871-1mlamf20	51	15	independent	independent	JJ
cord-016871-1mlamf20	51	16	predictor	predictor	NN
cord-016871-1mlamf20	51	17	of	of	IN
cord-016871-1mlamf20	51	18	substantial	substantial	JJ
cord-016871-1mlamf20	51	19	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	51	20	and	and	CC
cord-016871-1mlamf20	51	21	the	the	DT
cord-016871-1mlamf20	51	22	transfusion	transfusion	NN
cord-016871-1mlamf20	51	23	of	of	IN
cord-016871-1mlamf20	51	24	multiple	multiple	JJ
cord-016871-1mlamf20	51	25	units	unit	NNS
cord-016871-1mlamf20	51	26	of	of	IN
cord-016871-1mlamf20	51	27	RBC	RBC	NNP
cord-016871-1mlamf20	51	28	,	,	,
cord-016871-1mlamf20	51	29	plasma	plasma	NN
cord-016871-1mlamf20	51	30	,	,	,
cord-016871-1mlamf20	51	31	and	and	CC
cord-016871-1mlamf20	51	32	platelets	platelet	NNS
cord-016871-1mlamf20	51	33	[	[	-LRB-
cord-016871-1mlamf20	51	34	10	10	CD
cord-016871-1mlamf20	51	35	,	,	,
cord-016871-1mlamf20	51	36	11	11	CD
cord-016871-1mlamf20	51	37	]	]	-RRB-
cord-016871-1mlamf20	51	38	.	.	.
cord-016871-1mlamf20	52	1	As	as	IN
cord-016871-1mlamf20	52	2	such	such	JJ
cord-016871-1mlamf20	52	3	,	,	,
cord-016871-1mlamf20	52	4	when	when	WRB
cord-016871-1mlamf20	52	5	one	one	CD
cord-016871-1mlamf20	52	6	is	be	VBZ
cord-016871-1mlamf20	52	7	requesting	request	VBG
cord-016871-1mlamf20	52	8	uncross	uncross	VB
cord-016871-1mlamf20	52	9	-	-	HYPH
cord-016871-1mlamf20	52	10	matched	match	VBN
cord-016871-1mlamf20	52	11	product	product	NN
cord-016871-1mlamf20	52	12	for	for	IN
cord-016871-1mlamf20	52	13	transfusion	transfusion	NN
cord-016871-1mlamf20	52	14	,	,	,
cord-016871-1mlamf20	52	15	the	the	DT
cord-016871-1mlamf20	52	16	institution	institution	NN
cord-016871-1mlamf20	52	17	's	's	POS
cord-016871-1mlamf20	52	18	MTP	MTP	NNP
cord-016871-1mlamf20	52	19	should	should	MD
cord-016871-1mlamf20	52	20	be	be	VB
cord-016871-1mlamf20	52	21	activated	activate	VBN
cord-016871-1mlamf20	52	22	.	.	.
cord-016871-1mlamf20	53	1	Prior	prior	RB
cord-016871-1mlamf20	53	2	to	to	IN
cord-016871-1mlamf20	53	3	the	the	DT
cord-016871-1mlamf20	53	4	advent	advent	NN
cord-016871-1mlamf20	53	5	of	of	IN
cord-016871-1mlamf20	53	6	MTPs	mtp	NNS
cord-016871-1mlamf20	53	7	,	,	,
cord-016871-1mlamf20	53	8	resuscitation	resuscitation	NN
cord-016871-1mlamf20	53	9	protocols	protocol	NNS
cord-016871-1mlamf20	53	10	for	for	IN
cord-016871-1mlamf20	53	11	severely	severely	RB
cord-016871-1mlamf20	53	12	injured	injure	VBN
cord-016871-1mlamf20	53	13	patients	patient	NNS
cord-016871-1mlamf20	53	14	began	begin	VBD
cord-016871-1mlamf20	53	15	with	with	IN
cord-016871-1mlamf20	53	16	large	large	JJ
cord-016871-1mlamf20	53	17	volumes	volume	NNS
cord-016871-1mlamf20	53	18	of	of	IN
cord-016871-1mlamf20	53	19	crystalloid	crystalloid	NNP
cord-016871-1mlamf20	53	20	followed	follow	VBN
cord-016871-1mlamf20	53	21	by	by	IN
cord-016871-1mlamf20	53	22	RBC	RBC	NNP
cord-016871-1mlamf20	53	23	transfusions	transfusion	NNS
cord-016871-1mlamf20	53	24	.	.	.
cord-016871-1mlamf20	54	1	Later	later	RB
cord-016871-1mlamf20	54	2	on	on	RB
cord-016871-1mlamf20	54	3	,	,	,
cord-016871-1mlamf20	54	4	plasma	plasma	NN
cord-016871-1mlamf20	54	5	,	,	,
cord-016871-1mlamf20	54	6	platelets	platelet	NNS
cord-016871-1mlamf20	54	7	,	,	,
cord-016871-1mlamf20	54	8	and	and	CC
cord-016871-1mlamf20	54	9	cryoprecipitate	cryoprecipitate	NNP
cord-016871-1mlamf20	54	10	were	be	VBD
cord-016871-1mlamf20	54	11	administered	administer	VBN
cord-016871-1mlamf20	54	12	if	if	IN
cord-016871-1mlamf20	54	13	the	the	DT
cord-016871-1mlamf20	54	14	patient	patient	NN
cord-016871-1mlamf20	54	15	had	have	VBD
cord-016871-1mlamf20	54	16	survived	survive	VBN
cord-016871-1mlamf20	54	17	the	the	DT
cord-016871-1mlamf20	54	18	operating	operate	VBG
cord-016871-1mlamf20	54	19	theater	theater	NN
cord-016871-1mlamf20	54	20	and	and	CC
cord-016871-1mlamf20	54	21	then	then	RB
cord-016871-1mlamf20	54	22	only	only	RB
cord-016871-1mlamf20	54	23	based	base	VBN
cord-016871-1mlamf20	54	24	on	on	IN
cord-016871-1mlamf20	54	25	laboratory	laboratory	NN
cord-016871-1mlamf20	54	26	values	value	NNS
cord-016871-1mlamf20	54	27	and	and	CC
cord-016871-1mlamf20	54	28	the	the	DT
cord-016871-1mlamf20	54	29	opinion	opinion	NN
cord-016871-1mlamf20	54	30	of	of	IN
cord-016871-1mlamf20	54	31	anesthesiologists	anesthesiologist	NNS
cord-016871-1mlamf20	54	32	and	and	CC
cord-016871-1mlamf20	54	33	transfusion	transfusion	NN
cord-016871-1mlamf20	54	34	specialists	specialist	NNS
cord-016871-1mlamf20	54	35	.	.	.
cord-016871-1mlamf20	55	1	These	these	DT
cord-016871-1mlamf20	55	2	guidelines	guideline	NNS
cord-016871-1mlamf20	55	3	recommended	recommend	VBD
cord-016871-1mlamf20	55	4	transfusions	transfusion	NNS
cord-016871-1mlamf20	55	5	at	at	IN
cord-016871-1mlamf20	55	6	prothrombin	prothrombin	NN
cord-016871-1mlamf20	55	7	time	time	NN
cord-016871-1mlamf20	55	8	ratio	ratio	NN
cord-016871-1mlamf20	55	9	of	of	IN
cord-016871-1mlamf20	55	10	>	>	NNP
cord-016871-1mlamf20	55	11	1.5	1.5	CD
cord-016871-1mlamf20	55	12	,	,	,
cord-016871-1mlamf20	55	13	platelet	platelet	NN
cord-016871-1mlamf20	55	14	counts	count	NNS
cord-016871-1mlamf20	55	15	of	of	IN
cord-016871-1mlamf20	55	16	<	<	XX
cord-016871-1mlamf20	55	17	50	50	CD
cord-016871-1mlamf20	56	1	×	×	NNP
cord-016871-1mlamf20	56	2	10	10	CD
cord-016871-1mlamf20	56	3	9	9	CD
cord-016871-1mlamf20	56	4	/L	/l	CD
cord-016871-1mlamf20	56	5	,	,	,
cord-016871-1mlamf20	57	1	fi	fi	NNP
cord-016871-1mlamf20	57	2	brinogen	brinogen	NNP
cord-016871-1mlamf20	57	3	level	level	NN
cord-016871-1mlamf20	58	1	<	<	XX
cord-016871-1mlamf20	58	2	1.5	1.5	CD
cord-016871-1mlamf20	58	3	-	-	SYM
cord-016871-1mlamf20	58	4	2.0	2.0	CD
cord-016871-1mlamf20	58	5	g	g	NN
cord-016871-1mlamf20	58	6	/	/	SYM
cord-016871-1mlamf20	58	7	L	l	NN
cord-016871-1mlamf20	58	8	or	or	CC
cord-016871-1mlamf20	58	9	after	after	IN
cord-016871-1mlamf20	58	10	a	a	DT
cord-016871-1mlamf20	58	11	predetermined	predetermine	VBN
cord-016871-1mlamf20	58	12	volume	volume	NN
cord-016871-1mlamf20	58	13	loss	loss	NN
cord-016871-1mlamf20	58	14	.	.	.
cord-016871-1mlamf20	59	1	This	this	DT
cord-016871-1mlamf20	59	2	approach	approach	NN
cord-016871-1mlamf20	59	3	relied	rely	VBD
cord-016871-1mlamf20	59	4	on	on	IN
cord-016871-1mlamf20	59	5	a	a	DT
cord-016871-1mlamf20	59	6	reactive	reactive	JJ
cord-016871-1mlamf20	59	7	strategy	strategy	NN
cord-016871-1mlamf20	59	8	where	where	WRB
cord-016871-1mlamf20	59	9	the	the	DT
cord-016871-1mlamf20	59	10	clinician	clinician	NN
cord-016871-1mlamf20	59	11	was	be	VBD
cord-016871-1mlamf20	59	12	constantly	constantly	RB
cord-016871-1mlamf20	59	13	"	"	``
cord-016871-1mlamf20	59	14	catching	catch	VBG
cord-016871-1mlamf20	59	15	up	up	RP
cord-016871-1mlamf20	59	16	"	"	''
cord-016871-1mlamf20	59	17	with	with	IN
cord-016871-1mlamf20	59	18	values	value	NNS
cord-016871-1mlamf20	59	19	representing	represent	VBG
cord-016871-1mlamf20	59	20	an	an	DT
cord-016871-1mlamf20	59	21	earlier	early	JJR
cord-016871-1mlamf20	59	22	hemodynamic	hemodynamic	JJ
cord-016871-1mlamf20	59	23	state	state	NN
cord-016871-1mlamf20	59	24	of	of	IN
cord-016871-1mlamf20	59	25	the	the	DT
cord-016871-1mlamf20	59	26	patient	patient	NN
cord-016871-1mlamf20	59	27	[	[	-LRB-
cord-016871-1mlamf20	59	28	12	12	CD
cord-016871-1mlamf20	59	29	]	]	-RRB-
cord-016871-1mlamf20	59	30	.	.	.
cord-016871-1mlamf20	60	1	While	while	IN
cord-016871-1mlamf20	60	2	this	this	DT
cord-016871-1mlamf20	60	3	standard	standard	JJ
cord-016871-1mlamf20	60	4	resuscitation	resuscitation	NN
cord-016871-1mlamf20	60	5	method	method	NN
cord-016871-1mlamf20	60	6	is	be	VBZ
cord-016871-1mlamf20	60	7	adequate	adequate	JJ
cord-016871-1mlamf20	60	8	for	for	IN
cord-016871-1mlamf20	60	9	patients	patient	NNS
cord-016871-1mlamf20	60	10	who	who	WP
cord-016871-1mlamf20	60	11	are	be	VBP
cord-016871-1mlamf20	60	12	not	not	RB
cord-016871-1mlamf20	60	13	in	in	IN
cord-016871-1mlamf20	60	14	shock	shock	NN
cord-016871-1mlamf20	60	15	or	or	CC
cord-016871-1mlamf20	60	16	not	not	RB
cord-016871-1mlamf20	60	17	bleeding	bleed	VBG
cord-016871-1mlamf20	60	18	,	,	,
cord-016871-1mlamf20	60	19	studies	study	NNS
cord-016871-1mlamf20	60	20	have	have	VBP
cord-016871-1mlamf20	60	21	demonstrated	demonstrate	VBN
cord-016871-1mlamf20	60	22	that	that	IN
cord-016871-1mlamf20	60	23	it	-PRON-	PRP
cord-016871-1mlamf20	60	24	does	do	VBZ
cord-016871-1mlamf20	60	25	not	not	RB
cord-016871-1mlamf20	60	26	suf	suf	VB
cord-016871-1mlamf20	60	27	fi	fi	FW
cord-016871-1mlamf20	60	28	ce	ce	NN
cord-016871-1mlamf20	60	29	for	for	IN
cord-016871-1mlamf20	60	30	the	the	DT
cord-016871-1mlamf20	60	31	subset	subset	NN
cord-016871-1mlamf20	60	32	of	of	IN
cord-016871-1mlamf20	60	33	patients	patient	NNS
cord-016871-1mlamf20	60	34	who	who	WP
cord-016871-1mlamf20	60	35	have	have	VBP
cord-016871-1mlamf20	60	36	sustained	sustain	VBN
cord-016871-1mlamf20	60	37	serious	serious	JJ
cord-016871-1mlamf20	60	38	injuries	injury	NNS
cord-016871-1mlamf20	60	39	,	,	,
cord-016871-1mlamf20	60	40	are	be	VBP
cord-016871-1mlamf20	60	41	coagulopathic	coagulopathic	JJ
cord-016871-1mlamf20	60	42	or	or	CC
cord-016871-1mlamf20	60	43	in	in	IN
cord-016871-1mlamf20	60	44	shock	shock	NN
cord-016871-1mlamf20	60	45	[	[	-LRB-
cord-016871-1mlamf20	60	46	5	5	CD
cord-016871-1mlamf20	60	47	]	]	-RRB-
cord-016871-1mlamf20	60	48	.	.	.
cord-016871-1mlamf20	61	1	One	one	CD
cord-016871-1mlamf20	61	2	reason	reason	NN
cord-016871-1mlamf20	61	3	is	be	VBZ
cord-016871-1mlamf20	61	4	that	that	IN
cord-016871-1mlamf20	61	5	the	the	DT
cord-016871-1mlamf20	61	6	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	61	7	is	be	VBZ
cord-016871-1mlamf20	61	8	addressed	address	VBN
cord-016871-1mlamf20	61	9	after	after	IN
cord-016871-1mlamf20	61	10	a	a	DT
cord-016871-1mlamf20	61	11	time	time	NN
cord-016871-1mlamf20	61	12	lapse	lapse	NN
cord-016871-1mlamf20	61	13	since	since	IN
cord-016871-1mlamf20	61	14	the	the	DT
cord-016871-1mlamf20	61	15	original	original	JJ
cord-016871-1mlamf20	61	16	laboratory	laboratory	NN
cord-016871-1mlamf20	61	17	values	value	NNS
cord-016871-1mlamf20	61	18	were	be	VBD
cord-016871-1mlamf20	61	19	obtained	obtain	VBN
cord-016871-1mlamf20	61	20	.	.	.
cord-016871-1mlamf20	62	1	Other	other	JJ
cord-016871-1mlamf20	62	2	reasons	reason	NNS
cord-016871-1mlamf20	62	3	for	for	IN
cord-016871-1mlamf20	62	4	the	the	DT
cord-016871-1mlamf20	62	5	suboptimal	suboptimal	JJ
cord-016871-1mlamf20	62	6	results	result	NNS
cord-016871-1mlamf20	62	7	of	of	IN
cord-016871-1mlamf20	62	8	this	this	DT
cord-016871-1mlamf20	62	9	method	method	NN
cord-016871-1mlamf20	62	10	are	be	VBP
cord-016871-1mlamf20	62	11	due	due	JJ
cord-016871-1mlamf20	62	12	to	to	IN
cord-016871-1mlamf20	62	13	the	the	DT
cord-016871-1mlamf20	62	14	ratios	ratio	NNS
cord-016871-1mlamf20	62	15	of	of	IN
cord-016871-1mlamf20	62	16	each	each	DT
cord-016871-1mlamf20	62	17	blood	blood	NN
cord-016871-1mlamf20	62	18	component	component	NN
cord-016871-1mlamf20	62	19	[	[	-LRB-
cord-016871-1mlamf20	62	20	5	5	CD
cord-016871-1mlamf20	62	21	]	]	-RRB-
cord-016871-1mlamf20	62	22	product	product	NN
cord-016871-1mlamf20	62	23	infused	infuse	VBN
cord-016871-1mlamf20	62	24	.	.	.
cord-016871-1mlamf20	63	1	Speci	Speci	NNP
cord-016871-1mlamf20	63	2	fi	fi	NNP
cord-016871-1mlamf20	64	1	cally	cally	RB
cord-016871-1mlamf20	64	2	,	,	,
cord-016871-1mlamf20	64	3	evidence	evidence	NN
cord-016871-1mlamf20	64	4	exists	exist	VBZ
cord-016871-1mlamf20	64	5	that	that	WDT
cord-016871-1mlamf20	64	6	demonstrates	demonstrate	VBZ
cord-016871-1mlamf20	64	7	that	that	IN
cord-016871-1mlamf20	64	8	large	large	JJ
cord-016871-1mlamf20	64	9	volume	volume	NN
cord-016871-1mlamf20	64	10	of	of	IN
cord-016871-1mlamf20	64	11	crystalloid	crystalloid	NNP
cord-016871-1mlamf20	64	12	fl	fl	NNP
cord-016871-1mlamf20	64	13	uids	uids	NNPS
cord-016871-1mlamf20	64	14	is	be	VBZ
cord-016871-1mlamf20	64	15	associated	associate	VBN
cord-016871-1mlamf20	64	16	with	with	IN
cord-016871-1mlamf20	64	17	increased	increase	VBN
cord-016871-1mlamf20	64	18	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	64	19	and	and	CC
cord-016871-1mlamf20	64	20	lower	low	JJR
cord-016871-1mlamf20	64	21	survival	survival	NN
cord-016871-1mlamf20	64	22	rates	rate	NNS
cord-016871-1mlamf20	64	23	[	[	-LRB-
cord-016871-1mlamf20	64	24	13	13	CD
cord-016871-1mlamf20	64	25	]	]	-RRB-
cord-016871-1mlamf20	64	26	.	.	.
cord-016871-1mlamf20	65	1	It	-PRON-	PRP
cord-016871-1mlamf20	65	2	has	have	VBZ
cord-016871-1mlamf20	65	3	been	be	VBN
cord-016871-1mlamf20	65	4	hypothesized	hypothesize	VBN
cord-016871-1mlamf20	65	5	that	that	IN
cord-016871-1mlamf20	65	6	this	this	DT
cord-016871-1mlamf20	65	7	effect	effect	NN
cord-016871-1mlamf20	65	8	is	be	VBZ
cord-016871-1mlamf20	65	9	due	due	JJ
cord-016871-1mlamf20	65	10	to	to	IN
cord-016871-1mlamf20	65	11	insuf	insuf	NN
cord-016871-1mlamf20	65	12	fi	fi	NNP
cord-016871-1mlamf20	65	13	cient	cient	NN
cord-016871-1mlamf20	65	14	replenishing	replenishing	NN
cord-016871-1mlamf20	65	15	of	of	IN
cord-016871-1mlamf20	65	16	hemostasis	hemostasis	NN
cord-016871-1mlamf20	65	17	factors	factor	NNS
cord-016871-1mlamf20	65	18	,	,	,
cord-016871-1mlamf20	65	19	and	and	CC
cord-016871-1mlamf20	65	20	the	the	DT
cord-016871-1mlamf20	65	21	complex	complex	JJ
cord-016871-1mlamf20	65	22	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	65	23	of	of	IN
cord-016871-1mlamf20	65	24	dilution	dilution	NN
cord-016871-1mlamf20	65	25	,	,	,
cord-016871-1mlamf20	65	26	consumption	consumption	NN
cord-016871-1mlamf20	65	27	of	of	IN
cord-016871-1mlamf20	65	28	factors	factor	NNS
cord-016871-1mlamf20	65	29	,	,	,
cord-016871-1mlamf20	65	30	and	and	CC
cord-016871-1mlamf20	65	31	fi	fi	NNP
cord-016871-1mlamf20	65	32	brinolysis	brinolysis	NN
cord-016871-1mlamf20	65	33	is	be	VBZ
cord-016871-1mlamf20	65	34	not	not	RB
cord-016871-1mlamf20	65	35	adequately	adequately	RB
cord-016871-1mlamf20	65	36	addressed	address	VBN
cord-016871-1mlamf20	65	37	.	.	.
cord-016871-1mlamf20	66	1	MTPs	MTPs	NNP
cord-016871-1mlamf20	66	2	also	also	RB
cord-016871-1mlamf20	66	3	offer	offer	VBP
cord-016871-1mlamf20	66	4	the	the	DT
cord-016871-1mlamf20	66	5	advantage	advantage	NN
cord-016871-1mlamf20	66	6	of	of	IN
cord-016871-1mlamf20	66	7	reducing	reduce	VBG
cord-016871-1mlamf20	66	8	intraoperative	intraoperative	JJ
cord-016871-1mlamf20	66	9	crystalloid	crystalloid	NN
cord-016871-1mlamf20	66	10	use	use	NN
cord-016871-1mlamf20	66	11	and	and	CC
cord-016871-1mlamf20	66	12	hence	hence	RB
cord-016871-1mlamf20	66	13	,	,	,
cord-016871-1mlamf20	66	14	reducing	reduce	VBG
cord-016871-1mlamf20	66	15	opportunities	opportunity	NNS
cord-016871-1mlamf20	66	16	for	for	IN
cord-016871-1mlamf20	66	17	hemodilution	hemodilution	NN
cord-016871-1mlamf20	66	18	.	.	.
cord-016871-1mlamf20	67	1	Damage	damage	NN
cord-016871-1mlamf20	67	2	control	control	NN
cord-016871-1mlamf20	67	3	resuscitation	resuscitation	NN
cord-016871-1mlamf20	67	4	(	(	-LRB-
cord-016871-1mlamf20	67	5	DCR	DCR	NNP
cord-016871-1mlamf20	67	6	)	)	-RRB-
cord-016871-1mlamf20	67	7	expands	expand	VBZ
cord-016871-1mlamf20	67	8	on	on	IN
cord-016871-1mlamf20	67	9	the	the	DT
cord-016871-1mlamf20	67	10	MTP	MTP	NNP
cord-016871-1mlamf20	67	11	process	process	NN
cord-016871-1mlamf20	67	12	and	and	CC
cord-016871-1mlamf20	67	13	calls	call	NNS
cord-016871-1mlamf20	67	14	for	for	IN
cord-016871-1mlamf20	67	15	low	low	JJ
cord-016871-1mlamf20	67	16	-	-	HYPH
cord-016871-1mlamf20	67	17	volume	volume	NN
cord-016871-1mlamf20	67	18	resuscitation	resuscitation	NN
cord-016871-1mlamf20	67	19	,	,	,
cord-016871-1mlamf20	67	20	sparing	spare	VBG
cord-016871-1mlamf20	67	21	the	the	DT
cord-016871-1mlamf20	67	22	patient	patient	NN
cord-016871-1mlamf20	67	23	of	of	IN
cord-016871-1mlamf20	67	24	resuscitation	resuscitation	NN
cord-016871-1mlamf20	67	25	with	with	IN
cord-016871-1mlamf20	67	26	fl	fl	NNP
cord-016871-1mlamf20	67	27	uids	uid	NNS
cord-016871-1mlamf20	67	28	such	such	JJ
cord-016871-1mlamf20	67	29	as	as	IN
cord-016871-1mlamf20	67	30	crystalloids	crystalloid	NNS
cord-016871-1mlamf20	67	31	and	and	CC
cord-016871-1mlamf20	67	32	colloids	colloid	NNS
cord-016871-1mlamf20	67	33	that	that	WDT
cord-016871-1mlamf20	67	34	are	be	VBP
cord-016871-1mlamf20	67	35	low	low	JJ
cord-016871-1mlamf20	67	36	in	in	IN
cord-016871-1mlamf20	67	37	hemostasis	hemostasis	NN
cord-016871-1mlamf20	67	38	factors	factor	NNS
cord-016871-1mlamf20	67	39	[	[	-LRB-
cord-016871-1mlamf20	67	40	14	14	CD
cord-016871-1mlamf20	67	41	]	]	-RRB-
cord-016871-1mlamf20	67	42	.	.	.
cord-016871-1mlamf20	68	1	Instead	instead	RB
cord-016871-1mlamf20	68	2	,	,	,
cord-016871-1mlamf20	68	3	DCR	DCR	NNP
cord-016871-1mlamf20	68	4	adheres	adhere	VBZ
cord-016871-1mlamf20	68	5	to	to	IN
cord-016871-1mlamf20	68	6	transfusion	transfusion	NN
cord-016871-1mlamf20	68	7	of	of	IN
cord-016871-1mlamf20	68	8	blood	blood	NN
cord-016871-1mlamf20	68	9	products	product	NNS
cord-016871-1mlamf20	68	10	in	in	IN
cord-016871-1mlamf20	68	11	a	a	DT
cord-016871-1mlamf20	68	12	ratio	ratio	NN
cord-016871-1mlamf20	68	13	of	of	IN
cord-016871-1mlamf20	68	14	plasma	plasma	NN
cord-016871-1mlamf20	68	15	and	and	CC
cord-016871-1mlamf20	68	16	platelets	platelet	NNS
cord-016871-1mlamf20	68	17	to	to	IN
cord-016871-1mlamf20	68	18	red	red	JJ
cord-016871-1mlamf20	68	19	blood	blood	NN
cord-016871-1mlamf20	68	20	cells	cell	NNS
cord-016871-1mlamf20	68	21	consistent	consistent	JJ
cord-016871-1mlamf20	68	22	with	with	IN
cord-016871-1mlamf20	68	23	that	that	DT
cord-016871-1mlamf20	68	24	which	which	WDT
cord-016871-1mlamf20	68	25	is	be	VBZ
cord-016871-1mlamf20	68	26	being	be	VBG
cord-016871-1mlamf20	68	27	lost	lose	VBN
cord-016871-1mlamf20	68	28	to	to	IN
cord-016871-1mlamf20	68	29	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	68	30	.	.	.
cord-016871-1mlamf20	69	1	It	-PRON-	PRP
cord-016871-1mlamf20	69	2	also	also	RB
cord-016871-1mlamf20	69	3	involves	involve	VBZ
cord-016871-1mlamf20	69	4	more	more	RBR
cord-016871-1mlamf20	69	5	permissive	permissive	JJ
cord-016871-1mlamf20	69	6	hypertension	hypertension	NN
cord-016871-1mlamf20	69	7	,	,	,
cord-016871-1mlamf20	69	8	and	and	CC
cord-016871-1mlamf20	69	9	acting	act	VBG
cord-016871-1mlamf20	69	10	preemptively	preemptively	RB
cord-016871-1mlamf20	69	11	on	on	IN
cord-016871-1mlamf20	69	12	the	the	DT
cord-016871-1mlamf20	69	13	hypovolemic	hypovolemic	JJ
cord-016871-1mlamf20	69	14	,	,	,
cord-016871-1mlamf20	69	15	hemorrhaging	hemorrhage	VBG
cord-016871-1mlamf20	69	16	patient	patient	JJ
cord-016871-1mlamf20	69	17	.	.	.
cord-016871-1mlamf20	70	1	DCR	DCR	NNP
cord-016871-1mlamf20	70	2	is	be	VBZ
cord-016871-1mlamf20	70	3	also	also	RB
cord-016871-1mlamf20	70	4	supported	support	VBN
cord-016871-1mlamf20	70	5	by	by	IN
cord-016871-1mlamf20	70	6	fi	fi	NNP
cord-016871-1mlamf20	70	7	ndings	nding	NNS
cord-016871-1mlamf20	70	8	from	from	IN
cord-016871-1mlamf20	70	9	the	the	DT
cord-016871-1mlamf20	70	10	US	US	NNP
cord-016871-1mlamf20	70	11	Army	Army	NNP
cord-016871-1mlamf20	70	12	's	's	POS
cord-016871-1mlamf20	70	13	Institute	Institute	NNP
cord-016871-1mlamf20	70	14	of	of	IN
cord-016871-1mlamf20	70	15	Surgical	Surgical	NNP
cord-016871-1mlamf20	70	16	Research	Research	NNP
cord-016871-1mlamf20	70	17	,	,	,
cord-016871-1mlamf20	70	18	which	which	WDT
cord-016871-1mlamf20	70	19	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	70	20	improvement	improvement	NN
cord-016871-1mlamf20	70	21	in	in	IN
cord-016871-1mlamf20	70	22	outcomes	outcome	NNS
cord-016871-1mlamf20	70	23	in	in	IN
cord-016871-1mlamf20	70	24	severely	severely	RB
cord-016871-1mlamf20	70	25	bleeding	bleed	VBG
cord-016871-1mlamf20	70	26	patients	patient	NNS
cord-016871-1mlamf20	70	27	who	who	WP
cord-016871-1mlamf20	70	28	were	be	VBD
cord-016871-1mlamf20	70	29	transfused	transfuse	VBN
cord-016871-1mlamf20	70	30	in	in	IN
cord-016871-1mlamf20	70	31	ratios	ratio	NNS
cord-016871-1mlamf20	70	32	of	of	IN
cord-016871-1mlamf20	70	33	products	product	NNS
cord-016871-1mlamf20	70	34	similar	similar	JJ
cord-016871-1mlamf20	70	35	to	to	IN
cord-016871-1mlamf20	70	36	whole	whole	JJ
cord-016871-1mlamf20	70	37	blood	blood	NN
cord-016871-1mlamf20	70	38	.	.	.
cord-016871-1mlamf20	71	1	Civilian	civilian	JJ
cord-016871-1mlamf20	71	2	trauma	trauma	NN
cord-016871-1mlamf20	71	3	data	datum	NNS
cord-016871-1mlamf20	71	4	has	have	VBZ
cord-016871-1mlamf20	71	5	also	also	RB
cord-016871-1mlamf20	71	6	shown	show	VBN
cord-016871-1mlamf20	71	7	that	that	IN
cord-016871-1mlamf20	71	8	RBC	RBC	NNP
cord-016871-1mlamf20	71	9	to	to	IN
cord-016871-1mlamf20	71	10	plasma	plasma	NN
cord-016871-1mlamf20	71	11	ratio	ratio	NN
cord-016871-1mlamf20	71	12	between	between	IN
cord-016871-1mlamf20	71	13	3:2	3:2	CD
cord-016871-1mlamf20	71	14	and	and	CC
cord-016871-1mlamf20	71	15	1:1	1:1	CD
cord-016871-1mlamf20	71	16	lead	lead	NN
cord-016871-1mlamf20	71	17	to	to	IN
cord-016871-1mlamf20	71	18	reduced	reduce	VBN
cord-016871-1mlamf20	71	19	30-day	30-day	CD
cord-016871-1mlamf20	71	20	mortality	mortality	NN
cord-016871-1mlamf20	71	21	and	and	CC
cord-016871-1mlamf20	71	22	increased	increase	VBN
cord-016871-1mlamf20	71	23	odds	odd	NNS
cord-016871-1mlamf20	71	24	of	of	IN
cord-016871-1mlamf20	71	25	survival	survival	NN
cord-016871-1mlamf20	71	26	[	[	-LRB-
cord-016871-1mlamf20	71	27	5	5	CD
cord-016871-1mlamf20	71	28	]	]	-RRB-
cord-016871-1mlamf20	71	29	.	.	.
cord-016871-1mlamf20	72	1	Fox	Fox	NNP
cord-016871-1mlamf20	72	2	et	et	FW
cord-016871-1mlamf20	72	3	al	al	NNP
cord-016871-1mlamf20	72	4	.	.	.
cord-016871-1mlamf20	73	1	found	find	VBD
cord-016871-1mlamf20	73	2	that	that	IN
cord-016871-1mlamf20	73	3	patients	patient	NNS
cord-016871-1mlamf20	73	4	undergoing	undergo	VBG
cord-016871-1mlamf20	73	5	vascular	vascular	JJ
cord-016871-1mlamf20	73	6	surgery	surgery	NN
cord-016871-1mlamf20	73	7	with	with	IN
cord-016871-1mlamf20	73	8	DCR	DCR	NNP
cord-016871-1mlamf20	73	9	had	have	VBD
cord-016871-1mlamf20	73	10	improved	improve	VBN
cord-016871-1mlamf20	73	11	revascularization	revascularization	NN
cord-016871-1mlamf20	73	12	and	and	CC
cord-016871-1mlamf20	73	13	graft	graft	NN
cord-016871-1mlamf20	73	14	patency	patency	NN
cord-016871-1mlamf20	73	15	.	.	.
cord-016871-1mlamf20	74	1	Their	-PRON-	PRP$
cord-016871-1mlamf20	74	2	results	result	NNS
cord-016871-1mlamf20	74	3	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	74	4	that	that	IN
cord-016871-1mlamf20	74	5	recombinant	recombinant	JJ
cord-016871-1mlamf20	74	6	VIIa	VIIa	NNS
cord-016871-1mlamf20	74	7	,	,	,
cord-016871-1mlamf20	74	8	whole	whole	JJ
cord-016871-1mlamf20	74	9	blood	blood	NN
cord-016871-1mlamf20	74	10	,	,	,
cord-016871-1mlamf20	74	11	fresh	fresh	JJ
cord-016871-1mlamf20	74	12	frozen	frozen	JJ
cord-016871-1mlamf20	74	13	plasma	plasma	NN
cord-016871-1mlamf20	74	14	(	(	-LRB-
cord-016871-1mlamf20	74	15	FFP	FFP	NNP
cord-016871-1mlamf20	74	16	)	)	-RRB-
cord-016871-1mlamf20	74	17	,	,	,
cord-016871-1mlamf20	74	18	platelets	platelet	NNS
cord-016871-1mlamf20	74	19	,	,	,
cord-016871-1mlamf20	74	20	cryoprecipitate	cryoprecipitate	JJ
cord-016871-1mlamf20	74	21	and	and	CC
cord-016871-1mlamf20	74	22	minimal	minimal	JJ
cord-016871-1mlamf20	74	23	crystalloid	crystalloid	NN
cord-016871-1mlamf20	74	24	prevented	prevent	VBD
cord-016871-1mlamf20	74	25	early	early	JJ
cord-016871-1mlamf20	74	26	graft	graft	NN
cord-016871-1mlamf20	74	27	failures	failure	NNS
cord-016871-1mlamf20	74	28	[	[	-LRB-
cord-016871-1mlamf20	74	29	15	15	CD
cord-016871-1mlamf20	74	30	]	]	-RRB-
cord-016871-1mlamf20	74	31	.	.	.
cord-016871-1mlamf20	75	1	While	while	IN
cord-016871-1mlamf20	75	2	there	there	EX
cord-016871-1mlamf20	75	3	is	be	VBZ
cord-016871-1mlamf20	75	4	a	a	DT
cord-016871-1mlamf20	75	5	wealth	wealth	NN
cord-016871-1mlamf20	75	6	of	of	IN
cord-016871-1mlamf20	75	7	data	datum	NNS
cord-016871-1mlamf20	75	8	in	in	IN
cord-016871-1mlamf20	75	9	the	the	DT
cord-016871-1mlamf20	75	10	trauma	trauma	NN
cord-016871-1mlamf20	75	11	population	population	NN
cord-016871-1mlamf20	75	12	,	,	,
cord-016871-1mlamf20	75	13	less	less	JJR
cord-016871-1mlamf20	75	14	data	data	NN
cord-016871-1mlamf20	75	15	is	be	VBZ
cord-016871-1mlamf20	75	16	available	available	JJ
cord-016871-1mlamf20	75	17	regarding	regard	VBG
cord-016871-1mlamf20	75	18	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	75	19	in	in	IN
cord-016871-1mlamf20	75	20	the	the	DT
cord-016871-1mlamf20	75	21	severely	severely	RB
cord-016871-1mlamf20	75	22	bleeding	bleed	VBG
cord-016871-1mlamf20	75	23	patient	patient	NN
cord-016871-1mlamf20	75	24	in	in	IN
cord-016871-1mlamf20	75	25	other	other	JJ
cord-016871-1mlamf20	75	26	surgical	surgical	JJ
cord-016871-1mlamf20	75	27	specialties	specialty	NNS
cord-016871-1mlamf20	75	28	.	.	.
cord-016871-1mlamf20	76	1	It	-PRON-	PRP
cord-016871-1mlamf20	76	2	is	be	VBZ
cord-016871-1mlamf20	76	3	,	,	,
cord-016871-1mlamf20	76	4	however	however	RB
cord-016871-1mlamf20	76	5	,	,	,
cord-016871-1mlamf20	76	6	important	important	JJ
cord-016871-1mlamf20	76	7	to	to	TO
cord-016871-1mlamf20	76	8	consider	consider	VB
cord-016871-1mlamf20	76	9	the	the	DT
cord-016871-1mlamf20	76	10	underlying	underlie	VBG
cord-016871-1mlamf20	76	11	pathology	pathology	NN
cord-016871-1mlamf20	76	12	responsible	responsible	JJ
cord-016871-1mlamf20	76	13	for	for	IN
cord-016871-1mlamf20	76	14	exsanguination	exsanguination	NN
cord-016871-1mlamf20	76	15	,	,	,
cord-016871-1mlamf20	76	16	such	such	JJ
cord-016871-1mlamf20	76	17	as	as	IN
cord-016871-1mlamf20	76	18	in	in	IN
cord-016871-1mlamf20	76	19	obstetric	obstetric	JJ
cord-016871-1mlamf20	76	20	patients	patient	NNS
cord-016871-1mlamf20	76	21	,	,	,
cord-016871-1mlamf20	76	22	as	as	RB
cord-016871-1mlamf20	76	23	well	well	RB
cord-016871-1mlamf20	76	24	as	as	IN
cord-016871-1mlamf20	76	25	related	related	JJ
cord-016871-1mlamf20	76	26	comorbidities	comorbiditie	NNS
cord-016871-1mlamf20	76	27	,	,	,
cord-016871-1mlamf20	76	28	such	such	JJ
cord-016871-1mlamf20	76	29	as	as	IN
cord-016871-1mlamf20	76	30	uremia	uremia	NN
cord-016871-1mlamf20	76	31	,	,	,
cord-016871-1mlamf20	76	32	pharmacologic	pharmacologic	JJ
cord-016871-1mlamf20	76	33	anticoagulation	anticoagulation	NN
cord-016871-1mlamf20	76	34	,	,	,
cord-016871-1mlamf20	76	35	in	in	IN
cord-016871-1mlamf20	76	36	assessing	assess	VBG
cord-016871-1mlamf20	76	37	for	for	IN
cord-016871-1mlamf20	76	38	need	need	NN
cord-016871-1mlamf20	76	39	of	of	IN
cord-016871-1mlamf20	76	40	blood	blood	NN
cord-016871-1mlamf20	76	41	products	product	NNS
cord-016871-1mlamf20	76	42	[	[	-LRB-
cord-016871-1mlamf20	76	43	5	5	CD
cord-016871-1mlamf20	76	44	]	]	-RRB-
cord-016871-1mlamf20	76	45	.	.	.
cord-016871-1mlamf20	77	1	For	for	IN
cord-016871-1mlamf20	77	2	instance	instance	NN
cord-016871-1mlamf20	77	3	,	,	,
cord-016871-1mlamf20	77	4	Kılıç	Kılıç	NNP
cord-016871-1mlamf20	77	5	et	et	NNP
cord-016871-1mlamf20	77	6	al	al	NNP
cord-016871-1mlamf20	77	7	.	.	NNP
cord-016871-1mlamf20	77	8	's	's	POS
cord-016871-1mlamf20	77	9	review	review	NN
cord-016871-1mlamf20	77	10	of	of	IN
cord-016871-1mlamf20	77	11	resuscitation	resuscitation	NN
cord-016871-1mlamf20	77	12	in	in	IN
cord-016871-1mlamf20	77	13	patients	patient	NNS
cord-016871-1mlamf20	77	14	with	with	IN
cord-016871-1mlamf20	77	15	gastrointestinal	gastrointestinal	JJ
cord-016871-1mlamf20	77	16	bleeding	bleeding	NN
cord-016871-1mlamf20	77	17	found	find	VBD
cord-016871-1mlamf20	77	18	that	that	IN
cord-016871-1mlamf20	77	19	1:1:1	1:1:1	CD
cord-016871-1mlamf20	77	20	ratios	ratio	NNS
cord-016871-1mlamf20	77	21	of	of	IN
cord-016871-1mlamf20	77	22	pRBCs	prbc	NNS
cord-016871-1mlamf20	77	23	,	,	,
cord-016871-1mlamf20	77	24	FFPs	ffp	NNS
cord-016871-1mlamf20	77	25	,	,	,
cord-016871-1mlamf20	77	26	and	and	CC
cord-016871-1mlamf20	77	27	platelets	platelet	NNS
cord-016871-1mlamf20	77	28	reduced	reduce	VBD
cord-016871-1mlamf20	77	29	dilutional	dilutional	JJ
cord-016871-1mlamf20	77	30	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	77	31	,	,	,
cord-016871-1mlamf20	77	32	similarly	similarly	RB
cord-016871-1mlamf20	77	33	to	to	IN
cord-016871-1mlamf20	77	34	trauma	trauma	NN
cord-016871-1mlamf20	77	35	patients	patient	NNS
cord-016871-1mlamf20	77	36	[	[	-LRB-
cord-016871-1mlamf20	77	37	16	16	CD
cord-016871-1mlamf20	77	38	]	]	-RRB-
cord-016871-1mlamf20	77	39	.	.	.
cord-016871-1mlamf20	78	1	Patients	patient	NNS
cord-016871-1mlamf20	78	2	undergoing	undergo	VBG
cord-016871-1mlamf20	78	3	open	open	JJ
cord-016871-1mlamf20	78	4	thoracoabdominal	thoracoabdominal	JJ
cord-016871-1mlamf20	78	5	aortic	aortic	JJ
cord-016871-1mlamf20	78	6	aneurysm	aneurysm	NN
cord-016871-1mlamf20	78	7	repair	repair	NN
cord-016871-1mlamf20	78	8	are	be	VBP
cord-016871-1mlamf20	78	9	also	also	RB
cord-016871-1mlamf20	78	10	vulnerable	vulnerable	JJ
cord-016871-1mlamf20	78	11	to	to	IN
cord-016871-1mlamf20	78	12	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	78	13	due	due	IN
cord-016871-1mlamf20	78	14	to	to	IN
cord-016871-1mlamf20	78	15	systemic	systemic	JJ
cord-016871-1mlamf20	78	16	heparinization	heparinization	NN
cord-016871-1mlamf20	78	17	,	,	,
cord-016871-1mlamf20	78	18	hypothermia	hypothermia	NN
cord-016871-1mlamf20	78	19	,	,	,
cord-016871-1mlamf20	78	20	and	and	CC
cord-016871-1mlamf20	78	21	left	left	JJ
cord-016871-1mlamf20	78	22	-	-	HYPH
cord-016871-1mlamf20	78	23	heart	heart	NN
cord-016871-1mlamf20	78	24	bypass	bypass	NN
cord-016871-1mlamf20	78	25	with	with	IN
cord-016871-1mlamf20	78	26	a	a	DT
cord-016871-1mlamf20	78	27	centrifugal	centrifugal	JJ
cord-016871-1mlamf20	78	28	pump	pump	NN
cord-016871-1mlamf20	78	29	[	[	-LRB-
cord-016871-1mlamf20	78	30	17	17	CD
cord-016871-1mlamf20	78	31	]	]	-RRB-
cord-016871-1mlamf20	78	32	.	.	.
cord-016871-1mlamf20	79	1	As	as	RB
cord-016871-1mlamf20	79	2	well	well	RB
cord-016871-1mlamf20	79	3	,	,	,
cord-016871-1mlamf20	79	4	several	several	JJ
cord-016871-1mlamf20	79	5	authors	author	NNS
cord-016871-1mlamf20	79	6	have	have	VBP
cord-016871-1mlamf20	79	7	noted	note	VBN
cord-016871-1mlamf20	79	8	its	-PRON-	PRP$
cord-016871-1mlamf20	79	9	bene	bene	NN
cord-016871-1mlamf20	79	10	fi	fi	NN
cord-016871-1mlamf20	79	11	t	t	NN
cord-016871-1mlamf20	79	12	in	in	IN
cord-016871-1mlamf20	79	13	the	the	DT
cord-016871-1mlamf20	79	14	vascular	vascular	JJ
cord-016871-1mlamf20	79	15	population	population	NN
cord-016871-1mlamf20	79	16	[	[	-LRB-
cord-016871-1mlamf20	79	17	15	15	CD
cord-016871-1mlamf20	79	18	,	,	,
cord-016871-1mlamf20	79	19	18	18	CD
cord-016871-1mlamf20	79	20	,	,	,
cord-016871-1mlamf20	79	21	19	19	CD
cord-016871-1mlamf20	79	22	]	]	-RRB-
cord-016871-1mlamf20	79	23	.	.	.
cord-016871-1mlamf20	80	1	Mell	Mell	NNP
cord-016871-1mlamf20	80	2	evaluated	evaluate	VBD
cord-016871-1mlamf20	80	3	168	168	CD
cord-016871-1mlamf20	80	4	patients	patient	NNS
cord-016871-1mlamf20	80	5	with	with	IN
cord-016871-1mlamf20	80	6	ruptured	ruptured	JJ
cord-016871-1mlamf20	80	7	abdominal	abdominal	JJ
cord-016871-1mlamf20	80	8	aortic	aortic	JJ
cord-016871-1mlamf20	80	9	aneurysm	aneurysm	NN
cord-016871-1mlamf20	80	10	who	who	WP
cord-016871-1mlamf20	80	11	had	have	VBD
cord-016871-1mlamf20	80	12	massive	massive	JJ
cord-016871-1mlamf20	80	13	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	80	14	in	in	IN
cord-016871-1mlamf20	80	15	the	the	DT
cord-016871-1mlamf20	80	16	perioperative	perioperative	JJ
cord-016871-1mlamf20	80	17	period	period	NN
cord-016871-1mlamf20	80	18	.	.	.
cord-016871-1mlamf20	81	1	Their	-PRON-	PRP$
cord-016871-1mlamf20	81	2	fi	fi	NN
cord-016871-1mlamf20	81	3	ndings	nding	NNS
cord-016871-1mlamf20	81	4	showed	show	VBD
cord-016871-1mlamf20	81	5	reduced	reduce	VBN
cord-016871-1mlamf20	81	6	30-day	30-day	CD
cord-016871-1mlamf20	81	7	mortality	mortality	NN
cord-016871-1mlamf20	81	8	in	in	IN
cord-016871-1mlamf20	81	9	patients	patient	NNS
cord-016871-1mlamf20	81	10	who	who	WP
cord-016871-1mlamf20	81	11	were	be	VBD
cord-016871-1mlamf20	81	12	transfused	transfuse	VBN
cord-016871-1mlamf20	81	13	1:1	1:1	CD
cord-016871-1mlamf20	81	14	RBC	RBC	NNP
cord-016871-1mlamf20	81	15	to	to	IN
cord-016871-1mlamf20	81	16	plasma	plasma	NN
cord-016871-1mlamf20	81	17	ratios	ratio	NNS
cord-016871-1mlamf20	81	18	.	.	.
cord-016871-1mlamf20	82	1	These	these	DT
cord-016871-1mlamf20	82	2	patients	patient	NNS
cord-016871-1mlamf20	82	3	also	also	RB
cord-016871-1mlamf20	82	4	experienced	experience	VBD
cord-016871-1mlamf20	82	5	lower	low	JJR
cord-016871-1mlamf20	82	6	rates	rate	NNS
cord-016871-1mlamf20	82	7	of	of	IN
cord-016871-1mlamf20	82	8	colonic	colonic	JJ
cord-016871-1mlamf20	82	9	ischemia	ischemia	NN
cord-016871-1mlamf20	82	10	.	.	.
cord-016871-1mlamf20	83	1	The	the	DT
cord-016871-1mlamf20	83	2	value	value	NN
cord-016871-1mlamf20	83	3	of	of	IN
cord-016871-1mlamf20	83	4	this	this	DT
cord-016871-1mlamf20	83	5	study	study	NN
cord-016871-1mlamf20	83	6	is	be	VBZ
cord-016871-1mlamf20	83	7	that	that	IN
cord-016871-1mlamf20	83	8	the	the	DT
cord-016871-1mlamf20	83	9	average	average	JJ
cord-016871-1mlamf20	83	10	age	age	NN
cord-016871-1mlamf20	83	11	of	of	IN
cord-016871-1mlamf20	83	12	patients	patient	NNS
cord-016871-1mlamf20	83	13	was	be	VBD
cord-016871-1mlamf20	83	14	73	73	CD
cord-016871-1mlamf20	83	15	years	year	NNS
cord-016871-1mlamf20	83	16	,	,	,
cord-016871-1mlamf20	83	17	much	much	RB
cord-016871-1mlamf20	83	18	older	old	JJR
cord-016871-1mlamf20	83	19	than	than	IN
cord-016871-1mlamf20	83	20	the	the	DT
cord-016871-1mlamf20	83	21	average	average	JJ
cord-016871-1mlamf20	83	22	trauma	trauma	NN
cord-016871-1mlamf20	83	23	patient	patient	NN
cord-016871-1mlamf20	83	24	,	,	,
cord-016871-1mlamf20	83	25	demonstrating	demonstrate	VBG
cord-016871-1mlamf20	83	26	applicability	applicability	NN
cord-016871-1mlamf20	83	27	of	of	IN
cord-016871-1mlamf20	83	28	MTPs	mtp	NNS
cord-016871-1mlamf20	83	29	in	in	IN
cord-016871-1mlamf20	83	30	different	different	JJ
cord-016871-1mlamf20	83	31	patient	patient	NN
cord-016871-1mlamf20	83	32	age	age	NN
cord-016871-1mlamf20	83	33	populations	population	NNS
cord-016871-1mlamf20	83	34	[	[	-LRB-
cord-016871-1mlamf20	83	35	19	19	CD
cord-016871-1mlamf20	83	36	]	]	-RRB-
cord-016871-1mlamf20	83	37	.	.	.
cord-016871-1mlamf20	84	1	Lastly	lastly	RB
cord-016871-1mlamf20	84	2	,	,	,
cord-016871-1mlamf20	84	3	evidence	evidence	NN
cord-016871-1mlamf20	84	4	on	on	IN
cord-016871-1mlamf20	84	5	MTPs	mtp	NNS
cord-016871-1mlamf20	84	6	has	have	VBZ
cord-016871-1mlamf20	84	7	focused	focus	VBN
cord-016871-1mlamf20	84	8	on	on	IN
cord-016871-1mlamf20	84	9	the	the	DT
cord-016871-1mlamf20	84	10	acutely	acutely	RB
cord-016871-1mlamf20	84	11	bleeding	bleed	VBG
cord-016871-1mlamf20	84	12	surgical	surgical	JJ
cord-016871-1mlamf20	84	13	patient	patient	NN
cord-016871-1mlamf20	84	14	,	,	,
cord-016871-1mlamf20	84	15	and	and	CC
cord-016871-1mlamf20	84	16	less	less	JJR
cord-016871-1mlamf20	84	17	is	be	VBZ
cord-016871-1mlamf20	84	18	known	know	VBN
cord-016871-1mlamf20	84	19	about	about	IN
cord-016871-1mlamf20	84	20	patients	patient	NNS
cord-016871-1mlamf20	84	21	in	in	IN
cord-016871-1mlamf20	84	22	other	other	JJ
cord-016871-1mlamf20	84	23	surgical	surgical	JJ
cord-016871-1mlamf20	84	24	settings	setting	NNS
cord-016871-1mlamf20	84	25	.	.	.
cord-016871-1mlamf20	85	1	Due	due	IN
cord-016871-1mlamf20	85	2	to	to	IN
cord-016871-1mlamf20	85	3	the	the	DT
cord-016871-1mlamf20	85	4	less	less	RBR
cord-016871-1mlamf20	85	5	emergent	emergent	JJ
cord-016871-1mlamf20	85	6	nature	nature	NN
cord-016871-1mlamf20	85	7	of	of	IN
cord-016871-1mlamf20	85	8	such	such	JJ
cord-016871-1mlamf20	85	9	settings	setting	NNS
cord-016871-1mlamf20	85	10	,	,	,
cord-016871-1mlamf20	85	11	it	-PRON-	PRP
cord-016871-1mlamf20	85	12	is	be	VBZ
cord-016871-1mlamf20	85	13	likely	likely	JJ
cord-016871-1mlamf20	85	14	that	that	IN
cord-016871-1mlamf20	85	15	MTPs	mtp	NNS
cord-016871-1mlamf20	85	16	are	be	VBP
cord-016871-1mlamf20	85	17	activated	activate	VBN
cord-016871-1mlamf20	85	18	more	more	RBR
cord-016871-1mlamf20	85	19	reactively	reactively	RB
cord-016871-1mlamf20	85	20	,	,	,
cord-016871-1mlamf20	85	21	and	and	CC
cord-016871-1mlamf20	85	22	it	-PRON-	PRP
cord-016871-1mlamf20	85	23	may	may	MD
cord-016871-1mlamf20	85	24	have	have	VB
cord-016871-1mlamf20	85	25	a	a	DT
cord-016871-1mlamf20	85	26	different	different	JJ
cord-016871-1mlamf20	85	27	effect	effect	NN
cord-016871-1mlamf20	85	28	on	on	IN
cord-016871-1mlamf20	85	29	patient	patient	JJ
cord-016871-1mlamf20	85	30	outcome	outcome	NN
cord-016871-1mlamf20	85	31	[	[	-LRB-
cord-016871-1mlamf20	85	32	5	5	CD
cord-016871-1mlamf20	85	33	]	]	-RRB-
cord-016871-1mlamf20	85	34	.	.	.
cord-016871-1mlamf20	86	1	However	however	RB
cord-016871-1mlamf20	86	2	,	,	,
cord-016871-1mlamf20	86	3	some	some	DT
cord-016871-1mlamf20	86	4	groups	group	NNS
cord-016871-1mlamf20	86	5	have	have	VBP
cord-016871-1mlamf20	86	6	shown	show	VBN
cord-016871-1mlamf20	86	7	that	that	IN
cord-016871-1mlamf20	86	8	those	those	DT
cord-016871-1mlamf20	86	9	patients	patient	NNS
cord-016871-1mlamf20	86	10	receiving	receive	VBG
cord-016871-1mlamf20	86	11	less	less	JJR
cord-016871-1mlamf20	86	12	than	than	IN
cord-016871-1mlamf20	86	13	massive	massive	JJ
cord-016871-1mlamf20	86	14	transfusion	transfusion	NN
cord-016871-1mlamf20	86	15	levels	level	NNS
cord-016871-1mlamf20	86	16	may	may	MD
cord-016871-1mlamf20	86	17	still	still	RB
cord-016871-1mlamf20	86	18	bene	bene	VB
cord-016871-1mlamf20	86	19	fi	fi	NNP
cord-016871-1mlamf20	86	20	t	t	NN
cord-016871-1mlamf20	86	21	from	from	IN
cord-016871-1mlamf20	86	22	higher	high	JJR
cord-016871-1mlamf20	86	23	plasma	plasma	NN
cord-016871-1mlamf20	86	24	to	to	IN
cord-016871-1mlamf20	86	25	red	red	JJ
cord-016871-1mlamf20	86	26	blood	blood	NN
cord-016871-1mlamf20	86	27	cell	cell	NN
cord-016871-1mlamf20	86	28	ratios	ratio	NNS
cord-016871-1mlamf20	86	29	[	[	-LRB-
cord-016871-1mlamf20	86	30	20	20	CD
cord-016871-1mlamf20	86	31	]	]	-RRB-
cord-016871-1mlamf20	86	32	.	.	.
cord-016871-1mlamf20	87	1	Wafaisade	Wafaisade	NNP
cord-016871-1mlamf20	87	2	and	and	CC
cord-016871-1mlamf20	87	3	colleagues	colleague	NNS
cord-016871-1mlamf20	87	4	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	87	5	decreased	decrease	VBD
cord-016871-1mlamf20	87	6	mortality	mortality	NN
cord-016871-1mlamf20	87	7	rates	rate	NNS
cord-016871-1mlamf20	87	8	in	in	IN
cord-016871-1mlamf20	87	9	such	such	JJ
cord-016871-1mlamf20	87	10	patients	patient	NNS
cord-016871-1mlamf20	87	11	.	.	.
cord-016871-1mlamf20	88	1	Because	because	IN
cord-016871-1mlamf20	88	2	of	of	IN
cord-016871-1mlamf20	88	3	the	the	DT
cord-016871-1mlamf20	88	4	nature	nature	NN
cord-016871-1mlamf20	88	5	of	of	IN
cord-016871-1mlamf20	88	6	frozen	frozen	JJ
cord-016871-1mlamf20	88	7	plasma	plasma	NN
cord-016871-1mlamf20	88	8	,	,	,
cord-016871-1mlamf20	88	9	transfusion	transfusion	NN
cord-016871-1mlamf20	88	10	delays	delay	NNS
cord-016871-1mlamf20	88	11	of	of	IN
cord-016871-1mlamf20	88	12	45	45	CD
cord-016871-1mlamf20	88	13	min	min	NNS
cord-016871-1mlamf20	88	14	occur	occur	VBP
cord-016871-1mlamf20	88	15	as	as	IN
cord-016871-1mlamf20	88	16	units	unit	NNS
cord-016871-1mlamf20	88	17	are	be	VBP
cord-016871-1mlamf20	88	18	thawed	thaw	VBN
cord-016871-1mlamf20	88	19	and	and	CC
cord-016871-1mlamf20	88	20	prepared	prepare	VBN
cord-016871-1mlamf20	88	21	.	.	.
cord-016871-1mlamf20	89	1	Young	young	JJ
cord-016871-1mlamf20	89	2	and	and	CC
cord-016871-1mlamf20	89	3	colleagues	colleague	NNS
cord-016871-1mlamf20	89	4	surveyed	survey	VBD
cord-016871-1mlamf20	89	5	members	member	NNS
cord-016871-1mlamf20	89	6	of	of	IN
cord-016871-1mlamf20	89	7	the	the	DT
cord-016871-1mlamf20	89	8	University	University	NNP
cord-016871-1mlamf20	89	9	Health	Health	NNP
cord-016871-1mlamf20	89	10	System	System	NNP
cord-016871-1mlamf20	89	11	Consortium	Consortium	NNP
cord-016871-1mlamf20	89	12	,	,	,
cord-016871-1mlamf20	89	13	consisting	consist	VBG
cord-016871-1mlamf20	89	14	of	of	IN
cord-016871-1mlamf20	89	15	107	107	CD
cord-016871-1mlamf20	89	16	academic	academic	JJ
cord-016871-1mlamf20	89	17	medical	medical	JJ
cord-016871-1mlamf20	89	18	centers	center	NNS
cord-016871-1mlamf20	89	19	and	and	CC
cord-016871-1mlamf20	89	20	232	232	CD
cord-016871-1mlamf20	89	21	af	af	NN
cord-016871-1mlamf20	89	22	fi	fi	NN
cord-016871-1mlamf20	89	23	liated	liate	VBN
cord-016871-1mlamf20	89	24	hospitals	hospital	NNS
cord-016871-1mlamf20	89	25	and	and	CC
cord-016871-1mlamf20	89	26	found	find	VBD
cord-016871-1mlamf20	89	27	that	that	IN
cord-016871-1mlamf20	89	28	only	only	RB
cord-016871-1mlamf20	89	29	60	60	CD
cord-016871-1mlamf20	89	30	%	%	NN
cord-016871-1mlamf20	89	31	of	of	IN
cord-016871-1mlamf20	89	32	participating	participate	VBG
cord-016871-1mlamf20	89	33	hospitals	hospital	NNS
cord-016871-1mlamf20	89	34	had	have	VBD
cord-016871-1mlamf20	89	35	thawed	thaw	VBN
cord-016871-1mlamf20	89	36	plasma	plasma	NN
cord-016871-1mlamf20	89	37	suf	suf	NN
cord-016871-1mlamf20	89	38	fi	fi	NN
cord-016871-1mlamf20	89	39	cient	cient	NN
cord-016871-1mlamf20	89	40	for	for	IN
cord-016871-1mlamf20	89	41	the	the	DT
cord-016871-1mlamf20	89	42	fi	fi	NNP
cord-016871-1mlamf20	89	43	rst	rst	NN
cord-016871-1mlamf20	89	44	cycle	cycle	NN
cord-016871-1mlamf20	89	45	of	of	IN
cord-016871-1mlamf20	89	46	their	-PRON-	PRP$
cord-016871-1mlamf20	89	47	MTP	MTP	NNP
cord-016871-1mlamf20	89	48	.	.	.
cord-016871-1mlamf20	90	1	This	this	DT
cord-016871-1mlamf20	90	2	problem	problem	NN
cord-016871-1mlamf20	90	3	delays	delay	VBZ
cord-016871-1mlamf20	90	4	the	the	DT
cord-016871-1mlamf20	90	5	critical	critical	JJ
cord-016871-1mlamf20	90	6	availability	availability	NN
cord-016871-1mlamf20	90	7	of	of	IN
cord-016871-1mlamf20	90	8	plasma	plasma	NN
cord-016871-1mlamf20	90	9	in	in	IN
cord-016871-1mlamf20	90	10	the	the	DT
cord-016871-1mlamf20	90	11	initial	initial	JJ
cord-016871-1mlamf20	90	12	phase	phase	NN
cord-016871-1mlamf20	90	13	of	of	IN
cord-016871-1mlamf20	90	14	resuscitation	resuscitation	NN
cord-016871-1mlamf20	90	15	.	.	.
cord-016871-1mlamf20	91	1	Reviews	review	NNS
cord-016871-1mlamf20	91	2	of	of	IN
cord-016871-1mlamf20	91	3	plasma	plasma	NN
cord-016871-1mlamf20	91	4	,	,	,
cord-016871-1mlamf20	91	5	cryoprecipitate	cryoprecipitate	NN
cord-016871-1mlamf20	91	6	and	and	CC
cord-016871-1mlamf20	91	7	platelet	platelet	NN
cord-016871-1mlamf20	91	8	transfusions	transfusion	NNS
cord-016871-1mlamf20	91	9	alongside	alongside	IN
cord-016871-1mlamf20	91	10	massive	massive	JJ
cord-016871-1mlamf20	91	11	blood	blood	NN
cord-016871-1mlamf20	91	12	transfusion	transfusion	NN
cord-016871-1mlamf20	91	13	protocols	protocol	NNS
cord-016871-1mlamf20	91	14	have	have	VBP
cord-016871-1mlamf20	91	15	demonstrated	demonstrate	VBN
cord-016871-1mlamf20	91	16	that	that	IN
cord-016871-1mlamf20	91	17	earlier	early	JJR
cord-016871-1mlamf20	91	18	use	use	NN
cord-016871-1mlamf20	91	19	of	of	IN
cord-016871-1mlamf20	91	20	plasma	plasma	NN
cord-016871-1mlamf20	91	21	and	and	CC
cord-016871-1mlamf20	91	22	platelets	platelet	NNS
cord-016871-1mlamf20	91	23	in	in	IN
cord-016871-1mlamf20	91	24	trauma	trauma	NN
cord-016871-1mlamf20	91	25	patients	patient	NNS
cord-016871-1mlamf20	91	26	have	have	VBP
cord-016871-1mlamf20	91	27	decreased	decrease	VBN
cord-016871-1mlamf20	91	28	the	the	DT
cord-016871-1mlamf20	91	29	incidence	incidence	NN
cord-016871-1mlamf20	91	30	of	of	IN
cord-016871-1mlamf20	91	31	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	91	32	[	[	-LRB-
cord-016871-1mlamf20	91	33	21	21	CD
cord-016871-1mlamf20	91	34	]	]	-RRB-
cord-016871-1mlamf20	91	35	.	.	.
cord-016871-1mlamf20	92	1	Unfortunately	unfortunately	RB
cord-016871-1mlamf20	92	2	,	,	,
cord-016871-1mlamf20	92	3	by	by	IN
cord-016871-1mlamf20	92	4	the	the	DT
cord-016871-1mlamf20	92	5	time	time	NN
cord-016871-1mlamf20	92	6	one	one	CD
cord-016871-1mlamf20	92	7	or	or	CC
cord-016871-1mlamf20	92	8	more	more	JJR
cord-016871-1mlamf20	92	9	blood	blood	NN
cord-016871-1mlamf20	92	10	volumes	volume	NNS
cord-016871-1mlamf20	92	11	have	have	VBP
cord-016871-1mlamf20	92	12	been	be	VBN
cord-016871-1mlamf20	92	13	lost	lose	VBN
cord-016871-1mlamf20	92	14	,	,	,
cord-016871-1mlamf20	92	15	plasma	plasma	NN
cord-016871-1mlamf20	92	16	may	may	MD
cord-016871-1mlamf20	92	17	still	still	RB
cord-016871-1mlamf20	92	18	be	be	VB
cord-016871-1mlamf20	92	19	unavailable	unavailable	JJ
cord-016871-1mlamf20	92	20	in	in	IN
cord-016871-1mlamf20	92	21	the	the	DT
cord-016871-1mlamf20	92	22	absence	absence	NN
cord-016871-1mlamf20	92	23	of	of	IN
cord-016871-1mlamf20	92	24	a	a	DT
cord-016871-1mlamf20	92	25	thawed	thawed	JJ
cord-016871-1mlamf20	92	26	or	or	CC
cord-016871-1mlamf20	92	27	liquid	liquid	JJ
cord-016871-1mlamf20	92	28	plasma	plasma	NN
cord-016871-1mlamf20	92	29	program	program	NN
cord-016871-1mlamf20	92	30	.	.	.
cord-016871-1mlamf20	93	1	Hence	hence	RB
cord-016871-1mlamf20	93	2	,	,	,
cord-016871-1mlamf20	93	3	protocols	protocol	NNS
cord-016871-1mlamf20	93	4	have	have	VBP
cord-016871-1mlamf20	93	5	been	be	VBN
cord-016871-1mlamf20	93	6	established	establish	VBN
cord-016871-1mlamf20	93	7	to	to	TO
cord-016871-1mlamf20	93	8	reduce	reduce	VB
cord-016871-1mlamf20	93	9	wastage	wastage	NN
cord-016871-1mlamf20	93	10	of	of	IN
cord-016871-1mlamf20	93	11	products	product	NNS
cord-016871-1mlamf20	93	12	and	and	CC
cord-016871-1mlamf20	93	13	use	use	VB
cord-016871-1mlamf20	93	14	them	-PRON-	PRP
cord-016871-1mlamf20	93	15	for	for	IN
cord-016871-1mlamf20	93	16	patients	patient	NNS
cord-016871-1mlamf20	93	17	in	in	IN
cord-016871-1mlamf20	93	18	an	an	DT
cord-016871-1mlamf20	93	19	ef	ef	NNP
cord-016871-1mlamf20	93	20	fi	fi	NNP
cord-016871-1mlamf20	93	21	cacious	cacious	JJ
cord-016871-1mlamf20	93	22	manner	manner	NN
cord-016871-1mlamf20	93	23	[	[	-LRB-
cord-016871-1mlamf20	93	24	22	22	CD
cord-016871-1mlamf20	93	25	]	]	-RRB-
cord-016871-1mlamf20	93	26	.	.	.
cord-016871-1mlamf20	94	1	Red	red	JJ
cord-016871-1mlamf20	94	2	blood	blood	NN
cord-016871-1mlamf20	94	3	cells	cell	NNS
cord-016871-1mlamf20	94	4	are	be	VBP
cord-016871-1mlamf20	94	5	the	the	DT
cord-016871-1mlamf20	94	6	component	component	NN
cord-016871-1mlamf20	94	7	of	of	IN
cord-016871-1mlamf20	94	8	choice	choice	NN
cord-016871-1mlamf20	94	9	used	use	VBN
cord-016871-1mlamf20	94	10	to	to	TO
cord-016871-1mlamf20	94	11	restore	restore	VB
cord-016871-1mlamf20	94	12	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	94	13	levels	level	NNS
cord-016871-1mlamf20	94	14	in	in	IN
cord-016871-1mlamf20	94	15	resuscitation	resuscitation	NN
cord-016871-1mlamf20	94	16	.	.	.
cord-016871-1mlamf20	95	1	More	More	JJR
cord-016871-1mlamf20	95	2	than	than	IN
cord-016871-1mlamf20	95	3	30	30	CD
cord-016871-1mlamf20	95	4	%	%	NN
cord-016871-1mlamf20	95	5	of	of	IN
cord-016871-1mlamf20	95	6	intensive	intensive	JJ
cord-016871-1mlamf20	95	7	care	care	NN
cord-016871-1mlamf20	95	8	unit	unit	NN
cord-016871-1mlamf20	95	9	(	(	-LRB-
cord-016871-1mlamf20	95	10	ICU	ICU	NNP
cord-016871-1mlamf20	95	11	)	)	-RRB-
cord-016871-1mlamf20	95	12	patients	patient	NNS
cord-016871-1mlamf20	95	13	receive	receive	VBP
cord-016871-1mlamf20	95	14	RBC	RBC	NNP
cord-016871-1mlamf20	95	15	transfusions	transfusion	NNS
cord-016871-1mlamf20	95	16	and	and	CC
cord-016871-1mlamf20	95	17	more	more	JJR
cord-016871-1mlamf20	95	18	than	than	IN
cord-016871-1mlamf20	95	19	40	40	CD
cord-016871-1mlamf20	95	20	%	%	NN
cord-016871-1mlamf20	95	21	are	be	VBP
cord-016871-1mlamf20	95	22	transfused	transfuse	VBN
cord-016871-1mlamf20	95	23	during	during	IN
cord-016871-1mlamf20	95	24	hospitalization	hospitalization	NN
cord-016871-1mlamf20	95	25	[	[	-LRB-
cord-016871-1mlamf20	95	26	23	23	CD
cord-016871-1mlamf20	95	27	]	]	-RRB-
cord-016871-1mlamf20	95	28	.	.	.
cord-016871-1mlamf20	96	1	The	the	DT
cord-016871-1mlamf20	96	2	Cardiovascular	Cardiovascular	NNP
cord-016871-1mlamf20	96	3	Health	Health	NNP
cord-016871-1mlamf20	96	4	Study	Study	NNP
cord-016871-1mlamf20	96	5	found	find	VBD
cord-016871-1mlamf20	96	6	that	that	IN
cord-016871-1mlamf20	96	7	anemia	anemia	NN
cord-016871-1mlamf20	96	8	is	be	VBZ
cord-016871-1mlamf20	96	9	associated	associate	VBN
cord-016871-1mlamf20	96	10	with	with	IN
cord-016871-1mlamf20	96	11	increased	increase	VBN
cord-016871-1mlamf20	96	12	mortality	mortality	NN
cord-016871-1mlamf20	96	13	in	in	IN
cord-016871-1mlamf20	96	14	elderly	elderly	JJ
cord-016871-1mlamf20	96	15	patients	patient	NNS
cord-016871-1mlamf20	96	16	,	,	,
cord-016871-1mlamf20	96	17	emphasizing	emphasize	VBG
cord-016871-1mlamf20	96	18	the	the	DT
cord-016871-1mlamf20	96	19	importance	importance	NN
cord-016871-1mlamf20	96	20	of	of	IN
cord-016871-1mlamf20	96	21	treatment	treatment	NN
cord-016871-1mlamf20	96	22	[	[	-LRB-
cord-016871-1mlamf20	96	23	24	24	CD
cord-016871-1mlamf20	96	24	]	]	-RRB-
cord-016871-1mlamf20	96	25	.	.	.
cord-016871-1mlamf20	97	1	However	however	RB
cord-016871-1mlamf20	97	2	,	,	,
cord-016871-1mlamf20	97	3	correction	correction	NN
cord-016871-1mlamf20	97	4	of	of	IN
cord-016871-1mlamf20	97	5	anemia	anemia	NN
cord-016871-1mlamf20	97	6	in	in	IN
cord-016871-1mlamf20	97	7	surgical	surgical	JJ
cord-016871-1mlamf20	97	8	patients	patient	NNS
cord-016871-1mlamf20	97	9	has	have	VBZ
cord-016871-1mlamf20	97	10	not	not	RB
cord-016871-1mlamf20	97	11	been	be	VBN
cord-016871-1mlamf20	97	12	readily	readily	RB
cord-016871-1mlamf20	97	13	studied	study	VBN
cord-016871-1mlamf20	97	14	,	,	,
cord-016871-1mlamf20	97	15	and	and	CC
cord-016871-1mlamf20	97	16	its	-PRON-	PRP$
cord-016871-1mlamf20	97	17	bene	bene	NN
cord-016871-1mlamf20	97	18	fi	fi	NN
cord-016871-1mlamf20	97	19	ts	ts	NNP
cord-016871-1mlamf20	97	20	remain	remain	VBP
cord-016871-1mlamf20	97	21	controversial	controversial	JJ
cord-016871-1mlamf20	97	22	.	.	.
cord-016871-1mlamf20	98	1	In	in	IN
cord-016871-1mlamf20	98	2	their	-PRON-	PRP$
cord-016871-1mlamf20	98	3	review	review	NN
cord-016871-1mlamf20	98	4	,	,	,
cord-016871-1mlamf20	98	5	Englesbe	Englesbe	NNP
cord-016871-1mlamf20	98	6	et	et	NNP
cord-016871-1mlamf20	98	7	al	al	NNP
cord-016871-1mlamf20	98	8	.	.	.
cord-016871-1mlamf20	98	9	note	note	VB
cord-016871-1mlamf20	98	10	that	that	IN
cord-016871-1mlamf20	98	11	there	there	EX
cord-016871-1mlamf20	98	12	is	be	VBZ
cord-016871-1mlamf20	98	13	not	not	RB
cord-016871-1mlamf20	98	14	yet	yet	RB
cord-016871-1mlamf20	98	15	a	a	DT
cord-016871-1mlamf20	98	16	consensus	consensus	NN
cord-016871-1mlamf20	98	17	of	of	IN
cord-016871-1mlamf20	98	18	in	in	IN
cord-016871-1mlamf20	98	19	what	what	WDT
cord-016871-1mlamf20	98	20	degree	degree	NN
cord-016871-1mlamf20	98	21	of	of	IN
cord-016871-1mlamf20	98	22	anemia	anemia	NN
cord-016871-1mlamf20	98	23	can	can	MD
cord-016871-1mlamf20	98	24	RBC	RBC	NNP
cord-016871-1mlamf20	98	25	transfusions	transfusion	NNS
cord-016871-1mlamf20	98	26	offer	offer	VB
cord-016871-1mlamf20	98	27	a	a	DT
cord-016871-1mlamf20	98	28	bene	bene	NN
cord-016871-1mlamf20	98	29	fi	fi	NN
cord-016871-1mlamf20	98	30	t	t	NN
cord-016871-1mlamf20	98	31	[	[	-LRB-
cord-016871-1mlamf20	98	32	25	25	CD
cord-016871-1mlamf20	98	33	]	]	-RRB-
cord-016871-1mlamf20	98	34	.	.	.
cord-016871-1mlamf20	99	1	They	-PRON-	PRP
cord-016871-1mlamf20	99	2	discuss	discuss	VBP
cord-016871-1mlamf20	99	3	the	the	DT
cord-016871-1mlamf20	99	4	current	current	JJ
cord-016871-1mlamf20	99	5	fi	fi	NN
cord-016871-1mlamf20	99	6	ndings	nding	NNS
cord-016871-1mlamf20	99	7	by	by	IN
cord-016871-1mlamf20	99	8	various	various	JJ
cord-016871-1mlamf20	99	9	studies	study	NNS
cord-016871-1mlamf20	99	10	,	,	,
cord-016871-1mlamf20	99	11	which	which	WDT
cord-016871-1mlamf20	99	12	have	have	VBP
cord-016871-1mlamf20	99	13	found	find	VBN
cord-016871-1mlamf20	99	14	that	that	IN
cord-016871-1mlamf20	99	15	survival	survival	NN
cord-016871-1mlamf20	99	16	was	be	VBD
cord-016871-1mlamf20	99	17	not	not	RB
cord-016871-1mlamf20	99	18	increased	increase	VBN
cord-016871-1mlamf20	99	19	when	when	WRB
cord-016871-1mlamf20	99	20	postoperative	postoperative	JJ
cord-016871-1mlamf20	99	21	patients	patient	NNS
cord-016871-1mlamf20	99	22	were	be	VBD
cord-016871-1mlamf20	99	23	transfused	transfuse	VBN
cord-016871-1mlamf20	99	24	to	to	TO
cord-016871-1mlamf20	99	25	correct	correct	VB
cord-016871-1mlamf20	99	26	a	a	DT
cord-016871-1mlamf20	99	27	hematocrit	hematocrit	NN
cord-016871-1mlamf20	99	28	of	of	IN
cord-016871-1mlamf20	99	29	25	25	CD
cord-016871-1mlamf20	99	30	%	%	NN
cord-016871-1mlamf20	99	31	,	,	,
cord-016871-1mlamf20	99	32	and	and	CC
cord-016871-1mlamf20	99	33	similarly	similarly	RB
cord-016871-1mlamf20	99	34	,	,	,
cord-016871-1mlamf20	99	35	while	while	IN
cord-016871-1mlamf20	99	36	studies	study	NNS
cord-016871-1mlamf20	99	37	favor	favor	VBP
cord-016871-1mlamf20	99	38	transfusion	transfusion	NN
cord-016871-1mlamf20	99	39	in	in	IN
cord-016871-1mlamf20	99	40	cardiac	cardiac	JJ
cord-016871-1mlamf20	99	41	patients	patient	NNS
cord-016871-1mlamf20	99	42	with	with	IN
cord-016871-1mlamf20	99	43	a	a	DT
cord-016871-1mlamf20	99	44	hematocrit	hematocrit	NN
cord-016871-1mlamf20	99	45	of	of	IN
cord-016871-1mlamf20	99	46	33	33	CD
cord-016871-1mlamf20	99	47	%	%	NN
cord-016871-1mlamf20	99	48	or	or	CC
cord-016871-1mlamf20	99	49	less	less	JJR
cord-016871-1mlamf20	99	50	,	,	,
cord-016871-1mlamf20	100	1	a	a	DT
cord-016871-1mlamf20	100	2	true	true	JJ
cord-016871-1mlamf20	100	3	bene	bene	FW
cord-016871-1mlamf20	100	4	fi	fi	NN
cord-016871-1mlamf20	100	5	t	t	NN
cord-016871-1mlamf20	100	6	remains	remain	VBZ
cord-016871-1mlamf20	100	7	to	to	TO
cord-016871-1mlamf20	100	8	be	be	VB
cord-016871-1mlamf20	100	9	seen	see	VBN
cord-016871-1mlamf20	100	10	.	.	.
cord-016871-1mlamf20	101	1	Hence	hence	RB
cord-016871-1mlamf20	101	2	,	,	,
cord-016871-1mlamf20	101	3	they	-PRON-	PRP
cord-016871-1mlamf20	101	4	recommend	recommend	VBP
cord-016871-1mlamf20	101	5	making	make	VBG
cord-016871-1mlamf20	101	6	the	the	DT
cord-016871-1mlamf20	101	7	decision	decision	NN
cord-016871-1mlamf20	101	8	to	to	TO
cord-016871-1mlamf20	101	9	transfuse	transfuse	VB
cord-016871-1mlamf20	101	10	using	use	VBG
cord-016871-1mlamf20	101	11	a	a	DT
cord-016871-1mlamf20	101	12	host	host	NN
cord-016871-1mlamf20	101	13	of	of	IN
cord-016871-1mlamf20	101	14	physiological	physiological	JJ
cord-016871-1mlamf20	101	15	measures	measure	NNS
cord-016871-1mlamf20	101	16	and	and	CC
cord-016871-1mlamf20	101	17	evaluation	evaluation	NN
cord-016871-1mlamf20	101	18	of	of	IN
cord-016871-1mlamf20	101	19	the	the	DT
cord-016871-1mlamf20	101	20	patient	patient	NN
cord-016871-1mlamf20	101	21	's	's	POS
cord-016871-1mlamf20	101	22	compensatory	compensatory	JJ
cord-016871-1mlamf20	101	23	ability	ability	NN
cord-016871-1mlamf20	101	24	,	,	,
cord-016871-1mlamf20	101	25	not	not	RB
cord-016871-1mlamf20	101	26	only	only	RB
cord-016871-1mlamf20	101	27	the	the	DT
cord-016871-1mlamf20	101	28	hematocrit	hematocrit	NN
cord-016871-1mlamf20	101	29	.	.	.
cord-016871-1mlamf20	102	1	They	-PRON-	PRP
cord-016871-1mlamf20	102	2	have	have	VBP
cord-016871-1mlamf20	102	3	used	use	VBN
cord-016871-1mlamf20	102	4	a	a	DT
cord-016871-1mlamf20	102	5	trigger	trigger	NN
cord-016871-1mlamf20	102	6	of	of	IN
cord-016871-1mlamf20	102	7	a	a	DT
cord-016871-1mlamf20	102	8	hematocrit	hematocrit	NN
cord-016871-1mlamf20	102	9	of	of	IN
cord-016871-1mlamf20	102	10	16	16	CD
cord-016871-1mlamf20	102	11	%	%	NN
cord-016871-1mlamf20	102	12	for	for	IN
cord-016871-1mlamf20	102	13	initiating	initiate	VBG
cord-016871-1mlamf20	102	14	transfusion	transfusion	NN
cord-016871-1mlamf20	102	15	when	when	WRB
cord-016871-1mlamf20	102	16	the	the	DT
cord-016871-1mlamf20	102	17	patient	patient	NN
cord-016871-1mlamf20	102	18	has	have	VBZ
cord-016871-1mlamf20	102	19	excellent	excellent	JJ
cord-016871-1mlamf20	102	20	compensatory	compensatory	JJ
cord-016871-1mlamf20	102	21	ability	ability	NN
cord-016871-1mlamf20	102	22	,	,	,
cord-016871-1mlamf20	102	23	and	and	CC
cord-016871-1mlamf20	102	24	21	21	CD
cord-016871-1mlamf20	102	25	%	%	NN
cord-016871-1mlamf20	102	26	when	when	WRB
cord-016871-1mlamf20	102	27	this	this	DT
cord-016871-1mlamf20	102	28	is	be	VBZ
cord-016871-1mlamf20	102	29	not	not	RB
cord-016871-1mlamf20	102	30	the	the	DT
cord-016871-1mlamf20	102	31	case	case	NN
cord-016871-1mlamf20	102	32	[	[	-LRB-
cord-016871-1mlamf20	102	33	25	25	CD
cord-016871-1mlamf20	102	34	]	]	-RRB-
cord-016871-1mlamf20	102	35	.	.	.
cord-016871-1mlamf20	103	1	The	the	DT
cord-016871-1mlamf20	103	2	21	21	CD
cord-016871-1mlamf20	103	3	%	%	NN
cord-016871-1mlamf20	103	4	trigger	trigger	NN
cord-016871-1mlamf20	103	5	should	should	MD
cord-016871-1mlamf20	103	6	also	also	RB
cord-016871-1mlamf20	103	7	be	be	VB
cord-016871-1mlamf20	103	8	employed	employ	VBN
cord-016871-1mlamf20	103	9	in	in	IN
cord-016871-1mlamf20	103	10	stable	stable	JJ
cord-016871-1mlamf20	103	11	elderly	elderly	JJ
cord-016871-1mlamf20	103	12	patients	patient	NNS
cord-016871-1mlamf20	103	13	without	without	IN
cord-016871-1mlamf20	103	14	tachycardia	tachycardia	NN
cord-016871-1mlamf20	103	15	or	or	CC
cord-016871-1mlamf20	103	16	hypoxia	hypoxia	NN
cord-016871-1mlamf20	103	17	.	.	.
cord-016871-1mlamf20	104	1	Otherwise	otherwise	RB
cord-016871-1mlamf20	104	2	,	,	,
cord-016871-1mlamf20	104	3	their	-PRON-	PRP$
cord-016871-1mlamf20	104	4	investigations	investigation	NNS
cord-016871-1mlamf20	104	5	have	have	VBP
cord-016871-1mlamf20	104	6	not	not	RB
cord-016871-1mlamf20	104	7	yet	yet	RB
cord-016871-1mlamf20	104	8	shown	show	VBN
cord-016871-1mlamf20	104	9	bene	bene	NN
cord-016871-1mlamf20	104	10	fi	fi	FW
cord-016871-1mlamf20	104	11	ts	ts	NN
cord-016871-1mlamf20	104	12	in	in	IN
cord-016871-1mlamf20	104	13	strati	strati	NNP
cord-016871-1mlamf20	104	14	fi	fi	NNP
cord-016871-1mlamf20	104	15	cation	cation	NNP
cord-016871-1mlamf20	104	16	of	of	IN
cord-016871-1mlamf20	104	17	surgical	surgical	JJ
cord-016871-1mlamf20	104	18	patients	patient	NNS
cord-016871-1mlamf20	104	19	by	by	IN
cord-016871-1mlamf20	104	20	specialty	specialty	NN
cord-016871-1mlamf20	104	21	or	or	CC
cord-016871-1mlamf20	104	22	procedures	procedure	NNS
cord-016871-1mlamf20	104	23	.	.	.
cord-016871-1mlamf20	105	1	One	one	CD
cord-016871-1mlamf20	105	2	surgical	surgical	JJ
cord-016871-1mlamf20	105	3	population	population	NN
cord-016871-1mlamf20	105	4	that	that	WDT
cord-016871-1mlamf20	105	5	has	have	VBZ
cord-016871-1mlamf20	105	6	been	be	VBN
cord-016871-1mlamf20	105	7	studied	study	VBN
cord-016871-1mlamf20	105	8	with	with	IN
cord-016871-1mlamf20	105	9	regards	regard	NNS
cord-016871-1mlamf20	105	10	to	to	IN
cord-016871-1mlamf20	105	11	transfusion	transfusion	NN
cord-016871-1mlamf20	105	12	is	be	VBZ
cord-016871-1mlamf20	105	13	patients	patient	NNS
cord-016871-1mlamf20	105	14	undergoing	undergo	VBG
cord-016871-1mlamf20	105	15	infrarenal	infrarenal	JJ
cord-016871-1mlamf20	105	16	abdominal	abdominal	JJ
cord-016871-1mlamf20	105	17	aortic	aortic	JJ
cord-016871-1mlamf20	105	18	aneurysm	aneurysm	NN
cord-016871-1mlamf20	105	19	surgery	surgery	NN
cord-016871-1mlamf20	105	20	.	.	.
cord-016871-1mlamf20	106	1	A	a	DT
cord-016871-1mlamf20	106	2	meta	meta	JJ
cord-016871-1mlamf20	106	3	-	-	HYPH
cord-016871-1mlamf20	106	4	analysis	analysis	NN
cord-016871-1mlamf20	106	5	of	of	IN
cord-016871-1mlamf20	106	6	randomized	randomized	JJ
cord-016871-1mlamf20	106	7	controlled	control	VBN
cord-016871-1mlamf20	106	8	trials	trial	NNS
cord-016871-1mlamf20	106	9	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	106	10	that	that	IN
cord-016871-1mlamf20	106	11	intraoperative	intraoperative	JJ
cord-016871-1mlamf20	106	12	autotransfusion	autotransfusion	NN
cord-016871-1mlamf20	106	13	in	in	IN
cord-016871-1mlamf20	106	14	these	these	DT
cord-016871-1mlamf20	106	15	patients	patient	NNS
cord-016871-1mlamf20	106	16	decreased	decrease	VBD
cord-016871-1mlamf20	106	17	the	the	DT
cord-016871-1mlamf20	106	18	allogeneic	allogeneic	NN
cord-016871-1mlamf20	106	19	blood	blood	NN
cord-016871-1mlamf20	106	20	transfusion	transfusion	NN
cord-016871-1mlamf20	106	21	requirement	requirement	NN
cord-016871-1mlamf20	106	22	[	[	-LRB-
cord-016871-1mlamf20	106	23	26	26	CD
cord-016871-1mlamf20	106	24	]	]	-RRB-
cord-016871-1mlamf20	106	25	.	.	.
cord-016871-1mlamf20	107	1	High	high	JJ
cord-016871-1mlamf20	107	2	quality	quality	NN
cord-016871-1mlamf20	107	3	evidence	evidence	NN
cord-016871-1mlamf20	107	4	,	,	,
cord-016871-1mlamf20	107	5	notably	notably	RB
cord-016871-1mlamf20	107	6	Hébert	Hébert	NNP
cord-016871-1mlamf20	107	7	et	et	NNP
cord-016871-1mlamf20	107	8	al	al	NNP
cord-016871-1mlamf20	107	9	.	.	NNP
cord-016871-1mlamf20	107	10	's	's	POS
cord-016871-1mlamf20	107	11	,	,	,
cord-016871-1mlamf20	107	12	exists	exist	VBZ
cord-016871-1mlamf20	107	13	to	to	TO
cord-016871-1mlamf20	107	14	support	support	VB
cord-016871-1mlamf20	107	15	conservative	conservative	JJ
cord-016871-1mlamf20	107	16	triggers	trigger	NNS
cord-016871-1mlamf20	107	17	for	for	IN
cord-016871-1mlamf20	107	18	RBC	RBC	NNP
cord-016871-1mlamf20	107	19	transfusion	transfusion	NN
cord-016871-1mlamf20	107	20	in	in	IN
cord-016871-1mlamf20	107	21	critically	critically	RB
cord-016871-1mlamf20	107	22	ill	ill	JJ
cord-016871-1mlamf20	107	23	patients	patient	NNS
cord-016871-1mlamf20	107	24	[	[	-LRB-
cord-016871-1mlamf20	107	25	27	27	CD
cord-016871-1mlamf20	107	26	]	]	-RRB-
cord-016871-1mlamf20	107	27	.	.	.
cord-016871-1mlamf20	108	1	This	this	DT
cord-016871-1mlamf20	108	2	multicenter	multicenter	NN
cord-016871-1mlamf20	108	3	randomized	randomize	VBN
cord-016871-1mlamf20	108	4	,	,	,
cord-016871-1mlamf20	108	5	controlled	control	VBN
cord-016871-1mlamf20	108	6	,	,	,
cord-016871-1mlamf20	108	7	clinical	clinical	JJ
cord-016871-1mlamf20	108	8	trial	trial	NN
cord-016871-1mlamf20	108	9	of	of	IN
cord-016871-1mlamf20	108	10	838	838	CD
cord-016871-1mlamf20	108	11	critically	critically	RB
cord-016871-1mlamf20	108	12	ill	ill	JJ
cord-016871-1mlamf20	108	13	patients	patient	NNS
cord-016871-1mlamf20	108	14	compared	compare	VBD
cord-016871-1mlamf20	108	15	the	the	DT
cord-016871-1mlamf20	108	16	outcomes	outcome	NNS
cord-016871-1mlamf20	108	17	of	of	IN
cord-016871-1mlamf20	108	18	patients	patient	NNS
cord-016871-1mlamf20	108	19	who	who	WP
cord-016871-1mlamf20	108	20	were	be	VBD
cord-016871-1mlamf20	108	21	transfused	transfuse	VBN
cord-016871-1mlamf20	108	22	at	at	IN
cord-016871-1mlamf20	108	23	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	108	24	levels	level	NNS
cord-016871-1mlamf20	108	25	of	of	IN
cord-016871-1mlamf20	108	26	less	less	JJR
cord-016871-1mlamf20	108	27	than	than	IN
cord-016871-1mlamf20	108	28	7.0	7.0	CD
cord-016871-1mlamf20	108	29	g	g	NN
cord-016871-1mlamf20	108	30	/	/	SYM
cord-016871-1mlamf20	108	31	dL	dl	NN
cord-016871-1mlamf20	108	32	and	and	CC
cord-016871-1mlamf20	108	33	those	those	DT
cord-016871-1mlamf20	108	34	who	who	WP
cord-016871-1mlamf20	108	35	were	be	VBD
cord-016871-1mlamf20	108	36	transfused	transfuse	VBN
cord-016871-1mlamf20	108	37	at	at	IN
cord-016871-1mlamf20	108	38	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	108	39	levels	level	NNS
cord-016871-1mlamf20	108	40	below	below	IN
cord-016871-1mlamf20	108	41	10.0	10.0	CD
cord-016871-1mlamf20	108	42	g	g	NN
cord-016871-1mlamf20	108	43	/	/	SYM
cord-016871-1mlamf20	108	44	dL.	dL.	NNP
cord-016871-1mlamf20	109	1	Their	-PRON-	PRP$
cord-016871-1mlamf20	109	2	study	study	NN
cord-016871-1mlamf20	109	3	ultimately	ultimately	RB
cord-016871-1mlamf20	109	4	found	find	VBD
cord-016871-1mlamf20	109	5	that	that	IN
cord-016871-1mlamf20	109	6	the	the	DT
cord-016871-1mlamf20	109	7	more	more	RBR
cord-016871-1mlamf20	109	8	restrictive	restrictive	JJ
cord-016871-1mlamf20	109	9	trigger	trigger	NN
cord-016871-1mlamf20	109	10	of	of	IN
cord-016871-1mlamf20	109	11	7.0	7.0	CD
cord-016871-1mlamf20	109	12	g	g	NN
cord-016871-1mlamf20	109	13	/	/	SYM
cord-016871-1mlamf20	109	14	dL	dL	NNP
cord-016871-1mlamf20	109	15	was	be	VBD
cord-016871-1mlamf20	109	16	superior	superior	JJ
cord-016871-1mlamf20	109	17	to	to	IN
cord-016871-1mlamf20	109	18	the	the	DT
cord-016871-1mlamf20	109	19	liberal	liberal	JJ
cord-016871-1mlamf20	109	20	one	one	NN
cord-016871-1mlamf20	109	21	and	and	CC
cord-016871-1mlamf20	109	22	patients	patient	NNS
cord-016871-1mlamf20	109	23	experienced	experience	VBD
cord-016871-1mlamf20	109	24	improved	improve	VBN
cord-016871-1mlamf20	109	25	30-day	30-day	CD
cord-016871-1mlamf20	109	26	survival	survival	NN
cord-016871-1mlamf20	109	27	rates	rate	NNS
cord-016871-1mlamf20	109	28	.	.	.
cord-016871-1mlamf20	110	1	Of	of	IN
cord-016871-1mlamf20	110	2	note	note	NN
cord-016871-1mlamf20	110	3	,	,	,
cord-016871-1mlamf20	110	4	of	of	IN
cord-016871-1mlamf20	110	5	the	the	DT
cord-016871-1mlamf20	110	6	various	various	JJ
cord-016871-1mlamf20	110	7	patient	patient	JJ
cord-016871-1mlamf20	110	8	populations	population	NNS
cord-016871-1mlamf20	110	9	studied	study	VBD
cord-016871-1mlamf20	110	10	,	,	,
cord-016871-1mlamf20	110	11	this	this	DT
cord-016871-1mlamf20	110	12	improvement	improvement	NN
cord-016871-1mlamf20	110	13	was	be	VBD
cord-016871-1mlamf20	110	14	not	not	RB
cord-016871-1mlamf20	110	15	found	find	VBN
cord-016871-1mlamf20	110	16	to	to	TO
cord-016871-1mlamf20	110	17	be	be	VB
cord-016871-1mlamf20	110	18	signi	signi	NNP
cord-016871-1mlamf20	110	19	fi	fi	NNP
cord-016871-1mlamf20	110	20	ca	can	MD
cord-016871-1mlamf20	110	21	nt	not	RB
cord-016871-1mlamf20	110	22	in	in	IN
cord-016871-1mlamf20	110	23	patients	patient	NNS
cord-016871-1mlamf20	110	24	with	with	IN
cord-016871-1mlamf20	110	25	acute	acute	JJ
cord-016871-1mlamf20	110	26	myocardial	myocardial	JJ
cord-016871-1mlamf20	110	27	infarction	infarction	NN
cord-016871-1mlamf20	110	28	and	and	CC
cord-016871-1mlamf20	110	29	unstable	unstable	JJ
cord-016871-1mlamf20	110	30	angina	angina	NN
cord-016871-1mlamf20	110	31	[	[	-LRB-
cord-016871-1mlamf20	110	32	27	27	CD
cord-016871-1mlamf20	110	33	]	]	-RRB-
cord-016871-1mlamf20	110	34	.	.	.
cord-016871-1mlamf20	111	1	It	-PRON-	PRP
cord-016871-1mlamf20	111	2	is	be	VBZ
cord-016871-1mlamf20	111	3	important	important	JJ
cord-016871-1mlamf20	111	4	to	to	TO
cord-016871-1mlamf20	111	5	be	be	VB
cord-016871-1mlamf20	111	6	mindful	mindful	JJ
cord-016871-1mlamf20	111	7	of	of	IN
cord-016871-1mlamf20	111	8	false	false	JJ
cord-016871-1mlamf20	111	9	triggers	trigger	NNS
cord-016871-1mlamf20	111	10	for	for	IN
cord-016871-1mlamf20	111	11	transfusion	transfusion	NN
cord-016871-1mlamf20	111	12	,	,	,
cord-016871-1mlamf20	111	13	such	such	JJ
cord-016871-1mlamf20	111	14	as	as	IN
cord-016871-1mlamf20	111	15	anemia	anemia	NN
cord-016871-1mlamf20	111	16	due	due	IN
cord-016871-1mlamf20	111	17	to	to	IN
cord-016871-1mlamf20	111	18	hemodilution	hemodilution	NNP
cord-016871-1mlamf20	111	19	,	,	,
cord-016871-1mlamf20	111	20	commonly	commonly	RB
cord-016871-1mlamf20	111	21	seen	see	VBN
cord-016871-1mlamf20	111	22	in	in	IN
cord-016871-1mlamf20	111	23	patients	patient	NNS
cord-016871-1mlamf20	111	24	receiving	receive	VBG
cord-016871-1mlamf20	111	25	fl	fl	JJ
cord-016871-1mlamf20	111	26	uids	uid	NNS
cord-016871-1mlamf20	111	27	during	during	IN
cord-016871-1mlamf20	111	28	prolonged	prolong	VBN
cord-016871-1mlamf20	111	29	hospital	hospital	NN
cord-016871-1mlamf20	111	30	stays	stay	NNS
cord-016871-1mlamf20	111	31	.	.	.
cord-016871-1mlamf20	112	1	A	a	DT
cord-016871-1mlamf20	112	2	peripheral	peripheral	JJ
cord-016871-1mlamf20	112	3	hematocrit	hematocrit	NN
cord-016871-1mlamf20	112	4	is	be	VBZ
cord-016871-1mlamf20	112	5	not	not	RB
cord-016871-1mlamf20	112	6	enough	enough	JJ
cord-016871-1mlamf20	112	7	to	to	TO
cord-016871-1mlamf20	112	8	determine	determine	VB
cord-016871-1mlamf20	112	9	the	the	DT
cord-016871-1mlamf20	112	10	patient	patient	NN
cord-016871-1mlamf20	112	11	's	's	POS
cord-016871-1mlamf20	112	12	red	red	JJ
cord-016871-1mlamf20	112	13	blood	blood	NN
cord-016871-1mlamf20	112	14	cell	cell	NN
cord-016871-1mlamf20	112	15	levels	level	NNS
cord-016871-1mlamf20	112	16	,	,	,
cord-016871-1mlamf20	112	17	and	and	CC
cord-016871-1mlamf20	112	18	calculations	calculation	NNS
cord-016871-1mlamf20	112	19	of	of	IN
cord-016871-1mlamf20	112	20	total	total	JJ
cord-016871-1mlamf20	112	21	blood	blood	NN
cord-016871-1mlamf20	112	22	volume	volume	NN
cord-016871-1mlamf20	112	23	,	,	,
cord-016871-1mlamf20	112	24	red	red	JJ
cord-016871-1mlamf20	112	25	blood	blood	NN
cord-016871-1mlamf20	112	26	cell	cell	NN
cord-016871-1mlamf20	112	27	volumes	volume	NNS
cord-016871-1mlamf20	112	28	,	,	,
cord-016871-1mlamf20	112	29	and	and	CC
cord-016871-1mlamf20	112	30	normalized	normalize	VBN
cord-016871-1mlamf20	112	31	hematocrit	hematocrit	NN
cord-016871-1mlamf20	112	32	are	be	VBP
cord-016871-1mlamf20	112	33	necessary	necessary	JJ
cord-016871-1mlamf20	112	34	[	[	-LRB-
cord-016871-1mlamf20	112	35	28	28	CD
cord-016871-1mlamf20	112	36	]	]	-RRB-
cord-016871-1mlamf20	112	37	.	.	.
cord-016871-1mlamf20	113	1	Van	Van	NNP
cord-016871-1mlamf20	113	2	et	et	NNP
cord-016871-1mlamf20	113	3	al	al	NNP
cord-016871-1mlamf20	113	4	.	.	.
cord-016871-1mlamf20	114	1	report	report	VB
cord-016871-1mlamf20	114	2	that	that	IN
cord-016871-1mlamf20	114	3	relying	rely	VBG
cord-016871-1mlamf20	114	4	on	on	IN
cord-016871-1mlamf20	114	5	peripheral	peripheral	JJ
cord-016871-1mlamf20	114	6	hematocrit	hematocrit	NN
cord-016871-1mlamf20	114	7	alone	alone	RB
cord-016871-1mlamf20	114	8	resulted	result	VBD
cord-016871-1mlamf20	114	9	in	in	IN
cord-016871-1mlamf20	114	10	overdiagnosis	overdiagnosis	NN
cord-016871-1mlamf20	114	11	of	of	IN
cord-016871-1mlamf20	114	12	anemia	anemia	NN
cord-016871-1mlamf20	114	13	in	in	IN
cord-016871-1mlamf20	114	14	23.8	23.8	CD
cord-016871-1mlamf20	114	15	%	%	NN
cord-016871-1mlamf20	114	16	of	of	IN
cord-016871-1mlamf20	114	17	analyses	analysis	NNS
cord-016871-1mlamf20	114	18	,	,	,
cord-016871-1mlamf20	114	19	and	and	CC
cord-016871-1mlamf20	114	20	this	this	DT
cord-016871-1mlamf20	114	21	fi	fi	NN
cord-016871-1mlamf20	114	22	nding	nding	NN
cord-016871-1mlamf20	114	23	can	can	MD
cord-016871-1mlamf20	114	24	lead	lead	VB
cord-016871-1mlamf20	114	25	to	to	IN
cord-016871-1mlamf20	114	26	unnecessary	unnecessary	JJ
cord-016871-1mlamf20	114	27	transfusions	transfusion	NNS
cord-016871-1mlamf20	114	28	.	.	.
cord-016871-1mlamf20	115	1	Blood	blood	NN
cord-016871-1mlamf20	115	2	Volume	volume	NN
cord-016871-1mlamf20	115	3	Analyzers	analyzer	NNS
cord-016871-1mlamf20	115	4	are	be	VBP
cord-016871-1mlamf20	115	5	one	one	CD
cord-016871-1mlamf20	115	6	option	option	NN
cord-016871-1mlamf20	115	7	that	that	WDT
cord-016871-1mlamf20	115	8	has	have	VBZ
cord-016871-1mlamf20	115	9	been	be	VBN
cord-016871-1mlamf20	115	10	shown	show	VBN
cord-016871-1mlamf20	115	11	to	to	TO
cord-016871-1mlamf20	115	12	separate	separate	JJ
cord-016871-1mlamf20	115	13	anemia	anemia	NN
cord-016871-1mlamf20	115	14	due	due	IN
cord-016871-1mlamf20	115	15	to	to	IN
cord-016871-1mlamf20	115	16	hemodilution	hemodilution	NN
cord-016871-1mlamf20	115	17	compared	compare	VBN
cord-016871-1mlamf20	115	18	to	to	IN
cord-016871-1mlamf20	115	19	other	other	JJ
cord-016871-1mlamf20	115	20	sources	source	NNS
cord-016871-1mlamf20	115	21	such	such	JJ
cord-016871-1mlamf20	115	22	as	as	IN
cord-016871-1mlamf20	115	23	surgical	surgical	JJ
cord-016871-1mlamf20	115	24	bleeding	bleed	VBG
cord-016871-1mlamf20	115	25	[	[	-LRB-
cord-016871-1mlamf20	115	26	28	28	CD
cord-016871-1mlamf20	115	27	]	]	-RRB-
cord-016871-1mlamf20	115	28	.	.	.
cord-016871-1mlamf20	116	1	In	in	IN
cord-016871-1mlamf20	116	2	patients	patient	NNS
cord-016871-1mlamf20	116	3	with	with	IN
cord-016871-1mlamf20	116	4	prolonged	prolonged	JJ
cord-016871-1mlamf20	116	5	hospital	hospital	NN
cord-016871-1mlamf20	116	6	stays	stay	NNS
cord-016871-1mlamf20	116	7	and	and	CC
cord-016871-1mlamf20	116	8	critically	critically	RB
cord-016871-1mlamf20	116	9	ill	ill	JJ
cord-016871-1mlamf20	116	10	patients	patient	NNS
cord-016871-1mlamf20	116	11	,	,	,
cord-016871-1mlamf20	116	12	it	-PRON-	PRP
cord-016871-1mlamf20	116	13	is	be	VBZ
cord-016871-1mlamf20	116	14	important	important	JJ
cord-016871-1mlamf20	116	15	to	to	TO
cord-016871-1mlamf20	116	16	keep	keep	VB
cord-016871-1mlamf20	116	17	in	in	IN
cord-016871-1mlamf20	116	18	mind	mind	NN
cord-016871-1mlamf20	116	19	anemia	anemia	NN
cord-016871-1mlamf20	116	20	due	due	IN
cord-016871-1mlamf20	116	21	to	to	IN
cord-016871-1mlamf20	116	22	phlebotomy	phlebotomy	NN
cord-016871-1mlamf20	116	23	for	for	IN
cord-016871-1mlamf20	116	24	various	various	JJ
cord-016871-1mlamf20	116	25	laboratory	laboratory	NN
cord-016871-1mlamf20	116	26	testing	testing	NN
cord-016871-1mlamf20	116	27	and	and	CC
cord-016871-1mlamf20	116	28	other	other	JJ
cord-016871-1mlamf20	116	29	needs	need	NNS
cord-016871-1mlamf20	116	30	[	[	-LRB-
cord-016871-1mlamf20	116	31	23	23	CD
cord-016871-1mlamf20	116	32	]	]	-RRB-
cord-016871-1mlamf20	116	33	.	.	.
cord-016871-1mlamf20	117	1	Between	between	IN
cord-016871-1mlamf20	117	2	40	40	CD
cord-016871-1mlamf20	117	3	and	and	CC
cord-016871-1mlamf20	117	4	240	240	CD
cord-016871-1mlamf20	117	5	ml	ml	NNS
cord-016871-1mlamf20	117	6	of	of	IN
cord-016871-1mlamf20	117	7	blood	blood	NN
cord-016871-1mlamf20	117	8	per	per	IN
cord-016871-1mlamf20	117	9	day	day	NN
cord-016871-1mlamf20	117	10	is	be	VBZ
cord-016871-1mlamf20	117	11	collected	collect	VBN
cord-016871-1mlamf20	117	12	from	from	IN
cord-016871-1mlamf20	117	13	ICU	ICU	NNP
cord-016871-1mlamf20	117	14	patients	patient	NNS
cord-016871-1mlamf20	117	15	,	,	,
cord-016871-1mlamf20	117	16	with	with	IN
cord-016871-1mlamf20	117	17	surgical	surgical	JJ
cord-016871-1mlamf20	117	18	patients	patient	NNS
cord-016871-1mlamf20	117	19	generally	generally	RB
cord-016871-1mlamf20	117	20	on	on	IN
cord-016871-1mlamf20	117	21	the	the	DT
cord-016871-1mlamf20	117	22	higher	high	JJR
cord-016871-1mlamf20	117	23	end	end	NN
cord-016871-1mlamf20	117	24	.	.	.
cord-016871-1mlamf20	118	1	Hence	hence	RB
cord-016871-1mlamf20	118	2	,	,	,
cord-016871-1mlamf20	118	3	the	the	DT
cord-016871-1mlamf20	118	4	conservation	conservation	NN
cord-016871-1mlamf20	118	5	of	of	IN
cord-016871-1mlamf20	118	6	blood	blood	NN
cord-016871-1mlamf20	118	7	and	and	CC
cord-016871-1mlamf20	118	8	reducing	reduce	VBG
cord-016871-1mlamf20	118	9	unnecessary	unnecessary	JJ
cord-016871-1mlamf20	118	10	blood	blood	NN
cord-016871-1mlamf20	118	11	draws	draw	NNS
cord-016871-1mlamf20	118	12	is	be	VBZ
cord-016871-1mlamf20	118	13	key	key	JJ
cord-016871-1mlamf20	118	14	to	to	IN
cord-016871-1mlamf20	118	15	preventing	prevent	VBG
cord-016871-1mlamf20	118	16	a	a	DT
cord-016871-1mlamf20	118	17	need	need	NN
cord-016871-1mlamf20	118	18	for	for	IN
cord-016871-1mlamf20	118	19	pRBC	prbc	JJ
cord-016871-1mlamf20	118	20	transfusions	transfusion	NNS
cord-016871-1mlamf20	118	21	.	.	.
cord-016871-1mlamf20	119	1	Because	because	IN
cord-016871-1mlamf20	119	2	RBC	RBC	NNP
cord-016871-1mlamf20	119	3	transfusions	transfusion	NNS
cord-016871-1mlamf20	119	4	are	be	VBP
cord-016871-1mlamf20	119	5	associated	associate	VBN
cord-016871-1mlamf20	119	6	with	with	IN
cord-016871-1mlamf20	119	7	certain	certain	JJ
cord-016871-1mlamf20	119	8	risks	risk	NNS
cord-016871-1mlamf20	119	9	that	that	WDT
cord-016871-1mlamf20	119	10	are	be	VBP
cord-016871-1mlamf20	119	11	discussed	discuss	VBN
cord-016871-1mlamf20	119	12	in	in	IN
cord-016871-1mlamf20	119	13	a	a	DT
cord-016871-1mlamf20	119	14	later	later	JJ
cord-016871-1mlamf20	119	15	section	section	NN
cord-016871-1mlamf20	119	16	,	,	,
cord-016871-1mlamf20	119	17	it	-PRON-	PRP
cord-016871-1mlamf20	119	18	is	be	VBZ
cord-016871-1mlamf20	119	19	important	important	JJ
cord-016871-1mlamf20	119	20	to	to	TO
cord-016871-1mlamf20	119	21	also	also	RB
cord-016871-1mlamf20	119	22	consider	consider	VB
cord-016871-1mlamf20	119	23	possible	possible	JJ
cord-016871-1mlamf20	119	24	alternatives	alternative	NNS
cord-016871-1mlamf20	119	25	or	or	CC
cord-016871-1mlamf20	119	26	treatments	treatment	NNS
cord-016871-1mlamf20	119	27	that	that	WDT
cord-016871-1mlamf20	119	28	reduce	reduce	VBP
cord-016871-1mlamf20	119	29	transfusion	transfusion	NN
cord-016871-1mlamf20	119	30	requirements	requirement	NNS
cord-016871-1mlamf20	119	31	,	,	,
cord-016871-1mlamf20	119	32	such	such	JJ
cord-016871-1mlamf20	119	33	as	as	IN
cord-016871-1mlamf20	119	34	epoetin	epoetin	NNP
cord-016871-1mlamf20	119	35	alfa	alfa	NNP
cord-016871-1mlamf20	119	36	.	.	.
cord-016871-1mlamf20	120	1	Silver	silver	NN
cord-016871-1mlamf20	120	2	et	et	NNP
cord-016871-1mlamf20	120	3	al	al	NNP
cord-016871-1mlamf20	120	4	.	.	.
cord-016871-1mlamf20	121	1	's	's	POS
cord-016871-1mlamf20	122	1	randomized	randomized	JJ
cord-016871-1mlamf20	122	2	,	,	,
cord-016871-1mlamf20	122	3	double	double	JJ
cord-016871-1mlamf20	122	4	-	-	HYPH
cord-016871-1mlamf20	122	5	blind	blind	JJ
cord-016871-1mlamf20	122	6	,	,	,
cord-016871-1mlamf20	122	7	placebo	placebo	NN
cord-016871-1mlamf20	122	8	-	-	HYPH
cord-016871-1mlamf20	122	9	controlled	control	VBN
cord-016871-1mlamf20	122	10	trial	trial	NN
cord-016871-1mlamf20	122	11	investigated	investigate	VBD
cord-016871-1mlamf20	122	12	the	the	DT
cord-016871-1mlamf20	122	13	role	role	NN
cord-016871-1mlamf20	122	14	of	of	IN
cord-016871-1mlamf20	122	15	epoetin	epoetin	NNP
cord-016871-1mlamf20	122	16	alfa	alfa	NNP
cord-016871-1mlamf20	122	17	,	,	,
cord-016871-1mlamf20	122	18	a	a	DT
cord-016871-1mlamf20	122	19	recombinant	recombinant	JJ
cord-016871-1mlamf20	122	20	erythropoietin	erythropoietin	NN
cord-016871-1mlamf20	122	21	,	,	,
cord-016871-1mlamf20	122	22	in	in	IN
cord-016871-1mlamf20	122	23	reducing	reduce	VBG
cord-016871-1mlamf20	122	24	the	the	DT
cord-016871-1mlamf20	122	25	RBC	RBC	NNP
cord-016871-1mlamf20	122	26	transfusion	transfusion	NN
cord-016871-1mlamf20	122	27	requirement	requirement	NN
cord-016871-1mlamf20	122	28	of	of	IN
cord-016871-1mlamf20	122	29	long	long	JJ
cord-016871-1mlamf20	122	30	-	-	HYPH
cord-016871-1mlamf20	122	31	term	term	NN
cord-016871-1mlamf20	122	32	acute	acute	JJ
cord-016871-1mlamf20	122	33	care	care	NN
cord-016871-1mlamf20	122	34	patients	patient	NNS
cord-016871-1mlamf20	122	35	,	,	,
cord-016871-1mlamf20	122	36	thereby	thereby	RB
cord-016871-1mlamf20	122	37	reducing	reduce	VBG
cord-016871-1mlamf20	122	38	risks	risk	NNS
cord-016871-1mlamf20	122	39	associated	associate	VBN
cord-016871-1mlamf20	122	40	with	with	IN
cord-016871-1mlamf20	122	41	transfusions	transfusion	NNS
cord-016871-1mlamf20	122	42	[	[	-LRB-
cord-016871-1mlamf20	122	43	29	29	CD
cord-016871-1mlamf20	122	44	]	]	-RRB-
cord-016871-1mlamf20	122	45	.	.	.
cord-016871-1mlamf20	123	1	Their	-PRON-	PRP$
cord-016871-1mlamf20	123	2	fi	fi	NN
cord-016871-1mlamf20	123	3	ndings	nding	NNS
cord-016871-1mlamf20	123	4	showed	show	VBD
cord-016871-1mlamf20	123	5	that	that	IN
cord-016871-1mlamf20	123	6	treatment	treatment	NN
cord-016871-1mlamf20	123	7	with	with	IN
cord-016871-1mlamf20	123	8	epoetin	epoetin	NNP
cord-016871-1mlamf20	123	9	alfa	alfa	NNP
cord-016871-1mlamf20	123	10	signi	signi	NNP
cord-016871-1mlamf20	123	11	fi	fi	NNP
cord-016871-1mlamf20	123	12	cantly	cantly	RB
cord-016871-1mlamf20	123	13	increased	increase	VBN
cord-016871-1mlamf20	123	14	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	123	15	concentration	concentration	NN
cord-016871-1mlamf20	123	16	and	and	CC
cord-016871-1mlamf20	123	17	the	the	DT
cord-016871-1mlamf20	123	18	odds	odd	NNS
cord-016871-1mlamf20	123	19	ratio	ratio	NN
cord-016871-1mlamf20	123	20	for	for	IN
cord-016871-1mlamf20	123	21	receiving	receive	VBG
cord-016871-1mlamf20	123	22	an	an	DT
cord-016871-1mlamf20	123	23	RBC	RBC	NNP
cord-016871-1mlamf20	123	24	transfusion	transfusion	NN
cord-016871-1mlamf20	123	25	compared	compare	VBN
cord-016871-1mlamf20	123	26	to	to	IN
cord-016871-1mlamf20	123	27	patients	patient	NNS
cord-016871-1mlamf20	123	28	on	on	IN
cord-016871-1mlamf20	123	29	the	the	DT
cord-016871-1mlamf20	123	30	placebo	placebo	NN
cord-016871-1mlamf20	123	31	arm	arm	NN
cord-016871-1mlamf20	123	32	was	be	VBD
cord-016871-1mlamf20	123	33	0.28	0.28	CD
cord-016871-1mlamf20	123	34	[	[	-LRB-
cord-016871-1mlamf20	123	35	29	29	CD
cord-016871-1mlamf20	123	36	]	]	-RRB-
cord-016871-1mlamf20	123	37	.	.	.
cord-016871-1mlamf20	124	1	Additionally	additionally	RB
cord-016871-1mlamf20	124	2	,	,	,
cord-016871-1mlamf20	124	3	Vincent	Vincent	NNP
cord-016871-1mlamf20	124	4	et	et	NNP
cord-016871-1mlamf20	124	5	al	al	NNP
cord-016871-1mlamf20	124	6	.	.	.
cord-016871-1mlamf20	125	1	's	's	POS
cord-016871-1mlamf20	125	2	randomized	randomized	JJ
cord-016871-1mlamf20	125	3	,	,	,
cord-016871-1mlamf20	125	4	double	double	JJ
cord-016871-1mlamf20	125	5	-	-	HYPH
cord-016871-1mlamf20	125	6	blind	blind	JJ
cord-016871-1mlamf20	125	7	,	,	,
cord-016871-1mlamf20	125	8	placebo	placebo	NN
cord-016871-1mlamf20	125	9	-	-	HYPH
cord-016871-1mlamf20	125	10	controlled	control	VBN
cord-016871-1mlamf20	125	11	study	study	NN
cord-016871-1mlamf20	125	12	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	125	13	that	that	IN
cord-016871-1mlamf20	125	14	a	a	DT
cord-016871-1mlamf20	125	15	once	once	RB
cord-016871-1mlamf20	125	16	weekly	weekly	JJ
cord-016871-1mlamf20	125	17	dose	dose	NN
cord-016871-1mlamf20	125	18	of	of	IN
cord-016871-1mlamf20	125	19	epoetin	epoetin	NNP
cord-016871-1mlamf20	125	20	alfa	alfa	NNP
cord-016871-1mlamf20	125	21	augmented	augment	VBD
cord-016871-1mlamf20	125	22	the	the	DT
cord-016871-1mlamf20	125	23	erythropoietin	erythropoietin	NN
cord-016871-1mlamf20	125	24	response	response	NN
cord-016871-1mlamf20	125	25	[	[	-LRB-
cord-016871-1mlamf20	125	26	30	30	CD
cord-016871-1mlamf20	125	27	]	]	-RRB-
cord-016871-1mlamf20	125	28	.	.	.
cord-016871-1mlamf20	126	1	Knight	Knight	NNP
cord-016871-1mlamf20	126	2	et	et	NNP
cord-016871-1mlamf20	126	3	al	al	NNP
cord-016871-1mlamf20	126	4	.	.	NNP
cord-016871-1mlamf20	126	5	's	's	POS
cord-016871-1mlamf20	126	6	review	review	NN
cord-016871-1mlamf20	126	7	found	find	VBD
cord-016871-1mlamf20	126	8	that	that	IN
cord-016871-1mlamf20	126	9	patients	patient	NNS
cord-016871-1mlamf20	126	10	with	with	IN
cord-016871-1mlamf20	126	11	cancers	cancer	NNS
cord-016871-1mlamf20	126	12	of	of	IN
cord-016871-1mlamf20	126	13	various	various	JJ
cord-016871-1mlamf20	126	14	organs	organ	NNS
cord-016871-1mlamf20	126	15	who	who	WP
cord-016871-1mlamf20	126	16	did	do	VBD
cord-016871-1mlamf20	126	17	not	not	RB
cord-016871-1mlamf20	126	18	have	have	VB
cord-016871-1mlamf20	126	19	anemia	anemia	NN
cord-016871-1mlamf20	126	20	,	,	,
cord-016871-1mlamf20	126	21	most	most	RBS
cord-016871-1mlamf20	126	22	due	due	JJ
cord-016871-1mlamf20	126	23	to	to	IN
cord-016871-1mlamf20	126	24	correction	correction	NN
cord-016871-1mlamf20	126	25	with	with	IN
cord-016871-1mlamf20	126	26	epoetin	epoetin	NNP
cord-016871-1mlamf20	126	27	alfa	alfa	NNP
cord-016871-1mlamf20	126	28	,	,	,
cord-016871-1mlamf20	126	29	required	require	VBD
cord-016871-1mlamf20	126	30	less	less	JJR
cord-016871-1mlamf20	126	31	transfusions	transfusion	NNS
cord-016871-1mlamf20	126	32	and	and	CC
cord-016871-1mlamf20	126	33	experienced	experience	VBD
cord-016871-1mlamf20	126	34	more	more	JJR
cord-016871-1mlamf20	126	35	quality	quality	NN
cord-016871-1mlamf20	126	36	of	of	IN
cord-016871-1mlamf20	126	37	life	life	NN
cord-016871-1mlamf20	126	38	[	[	-LRB-
cord-016871-1mlamf20	126	39	31	31	CD
cord-016871-1mlamf20	126	40	]	]	-RRB-
cord-016871-1mlamf20	126	41	.	.	.
cord-016871-1mlamf20	127	1	However	however	RB
cord-016871-1mlamf20	127	2	,	,	,
cord-016871-1mlamf20	127	3	epoetin	epoetin	NNP
cord-016871-1mlamf20	127	4	alfa	alfa	NNP
cord-016871-1mlamf20	127	5	is	be	VBZ
cord-016871-1mlamf20	127	6	limited	limit	VBN
cord-016871-1mlamf20	127	7	by	by	IN
cord-016871-1mlamf20	127	8	its	-PRON-	PRP$
cord-016871-1mlamf20	127	9	delayed	delay	VBN
cord-016871-1mlamf20	127	10	onset	onset	NN
cord-016871-1mlamf20	127	11	at	at	IN
cord-016871-1mlamf20	127	12	5	5	CD
cord-016871-1mlamf20	127	13	-	-	SYM
cord-016871-1mlamf20	127	14	7	7	CD
cord-016871-1mlamf20	127	15	days	day	NNS
cord-016871-1mlamf20	127	16	.	.	.
cord-016871-1mlamf20	128	1	As	as	IN
cord-016871-1mlamf20	128	2	for	for	IN
cord-016871-1mlamf20	128	3	its	-PRON-	PRP$
cord-016871-1mlamf20	128	4	effects	effect	NNS
cord-016871-1mlamf20	128	5	on	on	IN
cord-016871-1mlamf20	128	6	mortality	mortality	NN
cord-016871-1mlamf20	128	7	,	,	,
cord-016871-1mlamf20	128	8	Corwin	Corwin	NNP
cord-016871-1mlamf20	128	9	et	et	NNP
cord-016871-1mlamf20	128	10	al	al	NNP
cord-016871-1mlamf20	128	11	.	.	NNP
cord-016871-1mlamf20	128	12	conducted	conduct	VBD
cord-016871-1mlamf20	128	13	a	a	DT
cord-016871-1mlamf20	128	14	prospective	prospective	NN
cord-016871-1mlamf20	128	15	,	,	,
cord-016871-1mlamf20	128	16	randomized	randomized	JJ
cord-016871-1mlamf20	128	17	,	,	,
cord-016871-1mlamf20	128	18	placebo	placebo	NN
cord-016871-1mlamf20	128	19	-	-	HYPH
cord-016871-1mlamf20	128	20	controlled	control	VBN
cord-016871-1mlamf20	128	21	trial	trial	NN
cord-016871-1mlamf20	128	22	of	of	IN
cord-016871-1mlamf20	128	23	1,460	1,460	CD
cord-016871-1mlamf20	128	24	medical	medical	JJ
cord-016871-1mlamf20	128	25	,	,	,
cord-016871-1mlamf20	128	26	surgical	surgical	JJ
cord-016871-1mlamf20	128	27	,	,	,
cord-016871-1mlamf20	128	28	or	or	CC
cord-016871-1mlamf20	128	29	trauma	trauma	NN
cord-016871-1mlamf20	128	30	patients	patient	NNS
cord-016871-1mlamf20	128	31	[	[	-LRB-
cord-016871-1mlamf20	128	32	32	32	CD
cord-016871-1mlamf20	128	33	]	]	-RRB-
cord-016871-1mlamf20	128	34	.	.	.
cord-016871-1mlamf20	129	1	Weekly	weekly	JJ
cord-016871-1mlamf20	129	2	injections	injection	NNS
cord-016871-1mlamf20	129	3	of	of	IN
cord-016871-1mlamf20	129	4	epoetin	epoetin	NNP
cord-016871-1mlamf20	129	5	alfa	alfa	NNP
cord-016871-1mlamf20	129	6	were	be	VBD
cord-016871-1mlamf20	129	7	shown	show	VBN
cord-016871-1mlamf20	129	8	to	to	TO
cord-016871-1mlamf20	129	9	decrease	decrease	VB
cord-016871-1mlamf20	129	10	mortality	mortality	NN
cord-016871-1mlamf20	129	11	at	at	IN
cord-016871-1mlamf20	129	12	day	day	NN
cord-016871-1mlamf20	129	13	29	29	CD
cord-016871-1mlamf20	129	14	and	and	CC
cord-016871-1mlamf20	129	15	day	day	NN
cord-016871-1mlamf20	129	16	140	140	CD
cord-016871-1mlamf20	129	17	,	,	,
cord-016871-1mlamf20	129	18	especially	especially	RB
cord-016871-1mlamf20	129	19	in	in	IN
cord-016871-1mlamf20	129	20	trauma	trauma	NN
cord-016871-1mlamf20	129	21	patients	patient	NNS
cord-016871-1mlamf20	129	22	compared	compare	VBN
cord-016871-1mlamf20	129	23	to	to	IN
cord-016871-1mlamf20	129	24	placebo	placebo	NN
cord-016871-1mlamf20	129	25	.	.	.
cord-016871-1mlamf20	130	1	However	however	RB
cord-016871-1mlamf20	130	2	,	,	,
cord-016871-1mlamf20	130	3	epoetin	epoetin	NNP
cord-016871-1mlamf20	130	4	alfa	alfa	NNP
cord-016871-1mlamf20	130	5	was	be	VBD
cord-016871-1mlamf20	130	6	associated	associate	VBN
cord-016871-1mlamf20	130	7	with	with	IN
cord-016871-1mlamf20	130	8	an	an	DT
cord-016871-1mlamf20	130	9	increase	increase	NN
cord-016871-1mlamf20	130	10	in	in	IN
cord-016871-1mlamf20	130	11	thrombotic	thrombotic	JJ
cord-016871-1mlamf20	130	12	events	event	NNS
cord-016871-1mlamf20	130	13	,	,	,
cord-016871-1mlamf20	130	14	and	and	CC
cord-016871-1mlamf20	130	15	did	do	VBD
cord-016871-1mlamf20	130	16	not	not	RB
cord-016871-1mlamf20	130	17	affect	affect	VB
cord-016871-1mlamf20	130	18	the	the	DT
cord-016871-1mlamf20	130	19	number	number	NN
cord-016871-1mlamf20	130	20	of	of	IN
cord-016871-1mlamf20	130	21	patients	patient	NNS
cord-016871-1mlamf20	130	22	who	who	WP
cord-016871-1mlamf20	130	23	received	receive	VBD
cord-016871-1mlamf20	130	24	a	a	DT
cord-016871-1mlamf20	130	25	transfusion	transfusion	NN
cord-016871-1mlamf20	130	26	of	of	IN
cord-016871-1mlamf20	130	27	RBCs	rbc	NNS
cord-016871-1mlamf20	130	28	[	[	-LRB-
cord-016871-1mlamf20	130	29	32	32	CD
cord-016871-1mlamf20	130	30	]	]	-RRB-
cord-016871-1mlamf20	130	31	.	.	.
cord-016871-1mlamf20	131	1	Iron	iron	NN
cord-016871-1mlamf20	131	2	sucrose	sucrose	NN
cord-016871-1mlamf20	131	3	has	have	VBZ
cord-016871-1mlamf20	131	4	also	also	RB
cord-016871-1mlamf20	131	5	been	be	VBN
cord-016871-1mlamf20	131	6	investigated	investigate	VBN
cord-016871-1mlamf20	131	7	as	as	IN
cord-016871-1mlamf20	131	8	a	a	DT
cord-016871-1mlamf20	131	9	possible	possible	JJ
cord-016871-1mlamf20	131	10	adjunct	adjunct	NN
cord-016871-1mlamf20	131	11	to	to	IN
cord-016871-1mlamf20	131	12	RBC	RBC	NNP
cord-016871-1mlamf20	131	13	transfusions	transfusion	NNS
cord-016871-1mlamf20	131	14	in	in	IN
cord-016871-1mlamf20	131	15	order	order	NN
cord-016871-1mlamf20	131	16	to	to	TO
cord-016871-1mlamf20	131	17	reduce	reduce	VB
cord-016871-1mlamf20	131	18	transfusion	transfusion	NN
cord-016871-1mlamf20	131	19	requirements	requirement	NNS
cord-016871-1mlamf20	131	20	.	.	.
cord-016871-1mlamf20	132	1	To	to	TO
cord-016871-1mlamf20	132	2	answer	answer	VB
cord-016871-1mlamf20	132	3	this	this	DT
cord-016871-1mlamf20	132	4	question	question	NN
cord-016871-1mlamf20	132	5	in	in	IN
cord-016871-1mlamf20	132	6	colorectal	colorectal	JJ
cord-016871-1mlamf20	132	7	cancer	cancer	NN
cord-016871-1mlamf20	132	8	surgery	surgery	NN
cord-016871-1mlamf20	132	9	patients	patient	NNS
cord-016871-1mlamf20	132	10	,	,	,
cord-016871-1mlamf20	132	11	Edwards	Edwards	NNP
cord-016871-1mlamf20	132	12	et	et	NNP
cord-016871-1mlamf20	132	13	al	al	NNP
cord-016871-1mlamf20	132	14	.	.	NNP
cord-016871-1mlamf20	132	15	conducted	conduct	VBD
cord-016871-1mlamf20	132	16	a	a	DT
cord-016871-1mlamf20	132	17	randomized	randomized	JJ
cord-016871-1mlamf20	132	18	prospective	prospective	JJ
cord-016871-1mlamf20	132	19	blinded	blinded	JJ
cord-016871-1mlamf20	132	20	placebo	placebo	NN
cord-016871-1mlamf20	132	21	-	-	HYPH
cord-016871-1mlamf20	132	22	controlled	control	VBN
cord-016871-1mlamf20	132	23	trial	trial	NN
cord-016871-1mlamf20	132	24	of	of	IN
cord-016871-1mlamf20	132	25	60	60	CD
cord-016871-1mlamf20	132	26	patients	patient	NNS
cord-016871-1mlamf20	132	27	[	[	-LRB-
cord-016871-1mlamf20	132	28	33	33	CD
cord-016871-1mlamf20	132	29	]	]	-RRB-
cord-016871-1mlamf20	132	30	.	.	.
cord-016871-1mlamf20	133	1	Patient	patient	JJ
cord-016871-1mlamf20	133	2	outcomes	outcome	NNS
cord-016871-1mlamf20	133	3	,	,	,
cord-016871-1mlamf20	133	4	which	which	WDT
cord-016871-1mlamf20	133	5	were	be	VBD
cord-016871-1mlamf20	133	6	assessed	assess	VBN
cord-016871-1mlamf20	133	7	using	use	VBG
cord-016871-1mlamf20	133	8	change	change	NN
cord-016871-1mlamf20	133	9	in	in	IN
cord-016871-1mlamf20	133	10	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	133	11	levels	level	NNS
cord-016871-1mlamf20	133	12	,	,	,
cord-016871-1mlamf20	133	13	serum	serum	NN
cord-016871-1mlamf20	133	14	iron	iron	NN
cord-016871-1mlamf20	133	15	markers	marker	NNS
cord-016871-1mlamf20	133	16	,	,	,
cord-016871-1mlamf20	133	17	transfusion	transfusion	NN
cord-016871-1mlamf20	133	18	rate	rate	NN
cord-016871-1mlamf20	133	19	,	,	,
cord-016871-1mlamf20	133	20	length	length	NN
cord-016871-1mlamf20	133	21	of	of	IN
cord-016871-1mlamf20	133	22	hospital	hospital	NN
cord-016871-1mlamf20	133	23	stay	stay	NN
cord-016871-1mlamf20	133	24	and	and	CC
cord-016871-1mlamf20	133	25	perioperative	perioperative	JJ
cord-016871-1mlamf20	133	26	events	event	NNS
cord-016871-1mlamf20	133	27	,	,	,
cord-016871-1mlamf20	133	28	were	be	VBD
cord-016871-1mlamf20	133	29	found	find	VBN
cord-016871-1mlamf20	133	30	to	to	TO
cord-016871-1mlamf20	133	31	be	be	VB
cord-016871-1mlamf20	133	32	unchanged	unchanged	JJ
cord-016871-1mlamf20	133	33	by	by	IN
cord-016871-1mlamf20	133	34	the	the	DT
cord-016871-1mlamf20	133	35	addition	addition	NN
cord-016871-1mlamf20	133	36	of	of	IN
cord-016871-1mlamf20	133	37	600	600	CD
cord-016871-1mlamf20	133	38	mg	mg	NN
cord-016871-1mlamf20	133	39	of	of	IN
cord-016871-1mlamf20	133	40	iron	iron	NN
cord-016871-1mlamf20	133	41	sucrose	sucrose	NN
cord-016871-1mlamf20	133	42	[	[	-LRB-
cord-016871-1mlamf20	133	43	33	33	CD
cord-016871-1mlamf20	133	44	]	]	-RRB-
cord-016871-1mlamf20	133	45	.	.	.
cord-016871-1mlamf20	134	1	Plasma	plasma	NN
cord-016871-1mlamf20	134	2	is	be	VBZ
cord-016871-1mlamf20	134	3	an	an	DT
cord-016871-1mlamf20	134	4	acellular	acellular	JJ
cord-016871-1mlamf20	134	5	blood	blood	NN
cord-016871-1mlamf20	134	6	product	product	NN
cord-016871-1mlamf20	134	7	consisting	consist	VBG
cord-016871-1mlamf20	134	8	of	of	IN
cord-016871-1mlamf20	134	9	clotting	clotting	NN
cord-016871-1mlamf20	134	10	factors	factor	NNS
cord-016871-1mlamf20	134	11	involved	involve	VBN
cord-016871-1mlamf20	134	12	in	in	IN
cord-016871-1mlamf20	134	13	coagulation	coagulation	NN
cord-016871-1mlamf20	134	14	and	and	CC
cord-016871-1mlamf20	134	15	fi	fi	NN
cord-016871-1mlamf20	134	16	brinolysis	brinolysis	NNP
cord-016871-1mlamf20	134	17	,	,	,
cord-016871-1mlamf20	134	18	as	as	RB
cord-016871-1mlamf20	134	19	well	well	RB
cord-016871-1mlamf20	134	20	as	as	IN
cord-016871-1mlamf20	134	21	proteins	protein	NNS
cord-016871-1mlamf20	134	22	involved	involve	VBN
cord-016871-1mlamf20	134	23	in	in	IN
cord-016871-1mlamf20	134	24	immune	immune	JJ
cord-016871-1mlamf20	134	25	reactions	reaction	NNS
cord-016871-1mlamf20	134	26	and	and	CC
cord-016871-1mlamf20	134	27	maintenance	maintenance	VB
cord-016871-1mlamf20	134	28	the	the	DT
cord-016871-1mlamf20	134	29	oncotic	oncotic	JJ
cord-016871-1mlamf20	134	30	balance	balance	NN
cord-016871-1mlamf20	134	31	of	of	IN
cord-016871-1mlamf20	134	32	blood	blood	NN
cord-016871-1mlamf20	134	33	.	.	.
cord-016871-1mlamf20	135	1	Plasma	plasma	NN
cord-016871-1mlamf20	135	2	can	can	MD
cord-016871-1mlamf20	135	3	be	be	VB
cord-016871-1mlamf20	135	4	obtained	obtain	VBN
cord-016871-1mlamf20	135	5	from	from	IN
cord-016871-1mlamf20	135	6	separation	separation	NN
cord-016871-1mlamf20	135	7	of	of	IN
cord-016871-1mlamf20	135	8	whole	whole	JJ
cord-016871-1mlamf20	135	9	blood	blood	NN
cord-016871-1mlamf20	135	10	or	or	CC
cord-016871-1mlamf20	135	11	unique	unique	JJ
cord-016871-1mlamf20	135	12	plasma	plasma	NN
cord-016871-1mlamf20	135	13	donations	donation	NNS
cord-016871-1mlamf20	135	14	from	from	IN
cord-016871-1mlamf20	135	15	a	a	DT
cord-016871-1mlamf20	135	16	donor	donor	NN
cord-016871-1mlamf20	135	17	using	use	VBG
cord-016871-1mlamf20	135	18	plasmapheresis	plasmapheresis	NN
cord-016871-1mlamf20	135	19	.	.	.
cord-016871-1mlamf20	136	1	Common	common	JJ
cord-016871-1mlamf20	136	2	indications	indication	NNS
cord-016871-1mlamf20	136	3	for	for	IN
cord-016871-1mlamf20	136	4	plasma	plasma	NN
cord-016871-1mlamf20	136	5	are	be	VBP
cord-016871-1mlamf20	136	6	reversal	reversal	NN
cord-016871-1mlamf20	136	7	of	of	IN
cord-016871-1mlamf20	136	8	warfarin	warfarin	NN
cord-016871-1mlamf20	136	9	-	-	HYPH
cord-016871-1mlamf20	136	10	induced	induce	VBN
cord-016871-1mlamf20	136	11	anticoagulation	anticoagulation	NN
cord-016871-1mlamf20	136	12	,	,	,
cord-016871-1mlamf20	136	13	massive	massive	JJ
cord-016871-1mlamf20	136	14	transfusion	transfusion	NN
cord-016871-1mlamf20	136	15	in	in	IN
cord-016871-1mlamf20	136	16	trauma	trauma	NN
cord-016871-1mlamf20	136	17	and	and	CC
cord-016871-1mlamf20	136	18	surgery	surgery	NN
cord-016871-1mlamf20	136	19	,	,	,
cord-016871-1mlamf20	136	20	procedures	procedure	NNS
cord-016871-1mlamf20	136	21	with	with	IN
cord-016871-1mlamf20	136	22	limited	limited	JJ
cord-016871-1mlamf20	136	23	bleeding	bleeding	NN
cord-016871-1mlamf20	136	24	or	or	CC
cord-016871-1mlamf20	136	25	risk	risk	NN
cord-016871-1mlamf20	136	26	thereof	thereof	RB
cord-016871-1mlamf20	136	27	,	,	,
cord-016871-1mlamf20	136	28	liver	liver	NN
cord-016871-1mlamf20	136	29	disease	disease	NN
cord-016871-1mlamf20	136	30	with	with	IN
cord-016871-1mlamf20	136	31	coagulation	coagulation	NN
cord-016871-1mlamf20	136	32	factor	factor	NN
cord-016871-1mlamf20	136	33	de	de	FW
cord-016871-1mlamf20	136	34	fi	fi	NNP
cord-016871-1mlamf20	136	35	ciencies	ciencie	NNS
cord-016871-1mlamf20	136	36	,	,	,
cord-016871-1mlamf20	136	37	single	single	JJ
cord-016871-1mlamf20	136	38	coagulation	coagulation	NN
cord-016871-1mlamf20	136	39	factor	factor	NN
cord-016871-1mlamf20	136	40	de	de	FW
cord-016871-1mlamf20	136	41	fi	fi	NNP
cord-016871-1mlamf20	136	42	ciency	ciency	NN
cord-016871-1mlamf20	136	43	,	,	,
cord-016871-1mlamf20	136	44	and	and	CC
cord-016871-1mlamf20	136	45	thrombotic	thrombotic	JJ
cord-016871-1mlamf20	136	46	thrombocytopenic	thrombocytopenic	JJ
cord-016871-1mlamf20	136	47	purpura	purpura	NN
cord-016871-1mlamf20	136	48	(	(	-LRB-
cord-016871-1mlamf20	136	49	TTP	TTP	NNP
cord-016871-1mlamf20	136	50	)	)	-RRB-
cord-016871-1mlamf20	137	1	[	[	-LRB-
cord-016871-1mlamf20	137	2	34	34	CD
cord-016871-1mlamf20	137	3	]	]	-RRB-
cord-016871-1mlamf20	137	4	.	.	.
cord-016871-1mlamf20	138	1	Historically	historically	RB
cord-016871-1mlamf20	138	2	,	,	,
cord-016871-1mlamf20	138	3	plasma	plasma	NN
cord-016871-1mlamf20	138	4	transfusions	transfusion	NNS
cord-016871-1mlamf20	138	5	have	have	VBP
cord-016871-1mlamf20	138	6	been	be	VBN
cord-016871-1mlamf20	138	7	associated	associate	VBN
cord-016871-1mlamf20	138	8	with	with	IN
cord-016871-1mlamf20	138	9	various	various	JJ
cord-016871-1mlamf20	138	10	side	side	NN
cord-016871-1mlamf20	138	11	effects	effect	NNS
cord-016871-1mlamf20	138	12	including	include	VBG
cord-016871-1mlamf20	138	13	transfusion	transfusion	NN
cord-016871-1mlamf20	138	14	related	relate	VBN
cord-016871-1mlamf20	138	15	acute	acute	JJ
cord-016871-1mlamf20	138	16	lung	lung	NN
cord-016871-1mlamf20	138	17	injury	injury	NN
cord-016871-1mlamf20	138	18	(	(	-LRB-
cord-016871-1mlamf20	138	19	TRALI	TRALI	NNP
cord-016871-1mlamf20	138	20	)	)	-RRB-
cord-016871-1mlamf20	139	1	[	[	-LRB-
cord-016871-1mlamf20	139	2	35	35	CD
cord-016871-1mlamf20	139	3	]	]	-RRB-
cord-016871-1mlamf20	139	4	.	.	.
cord-016871-1mlamf20	140	1	However	however	RB
cord-016871-1mlamf20	140	2	,	,	,
cord-016871-1mlamf20	140	3	these	these	DT
cord-016871-1mlamf20	140	4	complications	complication	NNS
cord-016871-1mlamf20	140	5	have	have	VBP
cord-016871-1mlamf20	140	6	been	be	VBN
cord-016871-1mlamf20	140	7	dramatically	dramatically	RB
cord-016871-1mlamf20	140	8	reduced	reduce	VBN
cord-016871-1mlamf20	140	9	with	with	IN
cord-016871-1mlamf20	140	10	blood	blood	NN
cord-016871-1mlamf20	140	11	donation	donation	NN
cord-016871-1mlamf20	140	12	centers	center	NNS
cord-016871-1mlamf20	140	13	transitioning	transition	VBG
cord-016871-1mlamf20	140	14	to	to	IN
cord-016871-1mlamf20	140	15	male	male	NN
cord-016871-1mlamf20	140	16	only	only	RB
cord-016871-1mlamf20	140	17	and/or	and/or	CC
cord-016871-1mlamf20	140	18	nulliparous	nulliparous	JJ
cord-016871-1mlamf20	140	19	female	female	JJ
cord-016871-1mlamf20	140	20	donors	donor	NNS
cord-016871-1mlamf20	140	21	[	[	-LRB-
cord-016871-1mlamf20	140	22	36	36	CD
cord-016871-1mlamf20	140	23	]	]	-RRB-
cord-016871-1mlamf20	140	24	.	.	.
cord-016871-1mlamf20	141	1	Norda	Norda	NNP
cord-016871-1mlamf20	141	2	et	et	NNP
cord-016871-1mlamf20	141	3	al	al	NNP
cord-016871-1mlamf20	141	4	.	.	.
cord-016871-1mlamf20	141	5	studied	study	VBD
cord-016871-1mlamf20	141	6	two	two	CD
cord-016871-1mlamf20	141	7	types	type	NNS
cord-016871-1mlamf20	141	8	of	of	IN
cord-016871-1mlamf20	141	9	plasma	plasma	NN
cord-016871-1mlamf20	141	10	:	:	:
cord-016871-1mlamf20	141	11	thawed	thaw	VBN
cord-016871-1mlamf20	141	12	plasma	plasma	NN
cord-016871-1mlamf20	141	13	and	and	CC
cord-016871-1mlamf20	141	14	liquid	liquid	NN
cord-016871-1mlamf20	141	15	plasma	plasma	NN
cord-016871-1mlamf20	141	16	(	(	-LRB-
cord-016871-1mlamf20	141	17	never	never	RB
cord-016871-1mlamf20	141	18	frozen	frozen	JJ
cord-016871-1mlamf20	141	19	)	)	-RRB-
cord-016871-1mlamf20	141	20	.	.	.
cord-016871-1mlamf20	142	1	Liquid	liquid	NN
cord-016871-1mlamf20	142	2	plasma	plasma	NN
cord-016871-1mlamf20	142	3	is	be	VBZ
cord-016871-1mlamf20	142	4	an	an	DT
cord-016871-1mlamf20	142	5	AABB	AABB	NNP
cord-016871-1mlamf20	142	6	approved	approve	VBN
cord-016871-1mlamf20	142	7	product	product	NN
cord-016871-1mlamf20	142	8	and	and	CC
cord-016871-1mlamf20	142	9	may	may	MD
cord-016871-1mlamf20	142	10	be	be	VB
cord-016871-1mlamf20	142	11	stored	store	VBN
cord-016871-1mlamf20	142	12	at	at	IN
cord-016871-1mlamf20	142	13	2	2	CD
cord-016871-1mlamf20	142	14	-	-	SYM
cord-016871-1mlamf20	142	15	6	6	CD
cord-016871-1mlamf20	142	16	°	°	NN
cord-016871-1mlamf20	142	17	C	c	NN
cord-016871-1mlamf20	142	18	for	for	IN
cord-016871-1mlamf20	142	19	up	up	IN
cord-016871-1mlamf20	142	20	to	to	TO
cord-016871-1mlamf20	142	21	26	26	CD
cord-016871-1mlamf20	142	22	days	day	NNS
cord-016871-1mlamf20	142	23	.	.	.
cord-016871-1mlamf20	143	1	Both	both	DT
cord-016871-1mlamf20	143	2	of	of	IN
cord-016871-1mlamf20	143	3	these	these	DT
cord-016871-1mlamf20	143	4	types	type	NNS
cord-016871-1mlamf20	143	5	of	of	IN
cord-016871-1mlamf20	143	6	plasma	plasma	NN
cord-016871-1mlamf20	143	7	have	have	VBP
cord-016871-1mlamf20	143	8	been	be	VBN
cord-016871-1mlamf20	143	9	considered	consider	VBN
cord-016871-1mlamf20	143	10	clinically	clinically	RB
cord-016871-1mlamf20	143	11	equivalent	equivalent	JJ
cord-016871-1mlamf20	143	12	.	.	.
cord-016871-1mlamf20	144	1	As	as	IN
cord-016871-1mlamf20	144	2	for	for	IN
cord-016871-1mlamf20	144	3	their	-PRON-	PRP$
cord-016871-1mlamf20	144	4	individual	individual	JJ
cord-016871-1mlamf20	144	5	components	component	NNS
cord-016871-1mlamf20	144	6	,	,	,
cord-016871-1mlamf20	144	7	liquid	liquid	JJ
cord-016871-1mlamf20	144	8	plasma	plasma	NN
cord-016871-1mlamf20	144	9	has	have	VBZ
cord-016871-1mlamf20	144	10	been	be	VBN
cord-016871-1mlamf20	144	11	shown	show	VBN
cord-016871-1mlamf20	144	12	to	to	TO
cord-016871-1mlamf20	144	13	contain	contain	VB
cord-016871-1mlamf20	144	14	levels	level	NNS
cord-016871-1mlamf20	144	15	of	of	IN
cord-016871-1mlamf20	144	16	Factor	factor	NN
cord-016871-1mlamf20	144	17	V	V	NNP
cord-016871-1mlamf20	144	18	and	and	CC
cord-016871-1mlamf20	144	19	von	von	NNP
cord-016871-1mlamf20	144	20	Willebrand	Willebrand	NNP
cord-016871-1mlamf20	144	21	factor	factor	NN
cord-016871-1mlamf20	144	22	at	at	IN
cord-016871-1mlamf20	144	23	levels	level	NNS
cord-016871-1mlamf20	144	24	70	70	CD
cord-016871-1mlamf20	144	25	%	%	NN
cord-016871-1mlamf20	144	26	or	or	CC
cord-016871-1mlamf20	144	27	greater	great	JJR
cord-016871-1mlamf20	144	28	.	.	.
cord-016871-1mlamf20	145	1	However	however	RB
cord-016871-1mlamf20	145	2	,	,	,
cord-016871-1mlamf20	145	3	studies	study	NNS
cord-016871-1mlamf20	145	4	have	have	VBP
cord-016871-1mlamf20	145	5	noted	note	VBN
cord-016871-1mlamf20	145	6	that	that	IN
cord-016871-1mlamf20	145	7	C1	C1	NNP
cord-016871-1mlamf20	145	8	esterase	esterase	NN
cord-016871-1mlamf20	145	9	inhibitor	inhibitor	NN
cord-016871-1mlamf20	145	10	(	(	-LRB-
cord-016871-1mlamf20	145	11	C1INH	C1INH	NNP
cord-016871-1mlamf20	145	12	)	)	-RRB-
cord-016871-1mlamf20	145	13	was	be	VBD
cord-016871-1mlamf20	145	14	consumed	consume	VBN
cord-016871-1mlamf20	145	15	by	by	IN
cord-016871-1mlamf20	145	16	day	day	NN
cord-016871-1mlamf20	145	17	14	14	CD
cord-016871-1mlamf20	145	18	in	in	IN
cord-016871-1mlamf20	145	19	22	22	CD
cord-016871-1mlamf20	145	20	%	%	NN
cord-016871-1mlamf20	145	21	of	of	IN
cord-016871-1mlamf20	145	22	plasma	plasma	NN
cord-016871-1mlamf20	145	23	products	product	NNS
cord-016871-1mlamf20	145	24	due	due	JJ
cord-016871-1mlamf20	145	25	to	to	IN
cord-016871-1mlamf20	145	26	coldinduced	coldinduced	NNP
cord-016871-1mlamf20	145	27	contact	contact	NN
cord-016871-1mlamf20	145	28	activation	activation	NN
cord-016871-1mlamf20	145	29	[	[	-LRB-
cord-016871-1mlamf20	145	30	37	37	CD
cord-016871-1mlamf20	145	31	]	]	-RRB-
cord-016871-1mlamf20	145	32	.	.	.
cord-016871-1mlamf20	146	1	In	in	IN
cord-016871-1mlamf20	146	2	order	order	NN
cord-016871-1mlamf20	146	3	to	to	TO
cord-016871-1mlamf20	146	4	avoid	avoid	VB
cord-016871-1mlamf20	146	5	this	this	DT
cord-016871-1mlamf20	146	6	effect	effect	NN
cord-016871-1mlamf20	146	7	that	that	WDT
cord-016871-1mlamf20	146	8	places	place	VBZ
cord-016871-1mlamf20	146	9	patients	patient	NNS
cord-016871-1mlamf20	146	10	at	at	IN
cord-016871-1mlamf20	146	11	risk	risk	NN
cord-016871-1mlamf20	146	12	for	for	IN
cord-016871-1mlamf20	146	13	inadequate	inadequate	JJ
cord-016871-1mlamf20	146	14	perfusion	perfusion	NN
cord-016871-1mlamf20	146	15	,	,	,
cord-016871-1mlamf20	146	16	some	some	DT
cord-016871-1mlamf20	146	17	institutions	institution	NNS
cord-016871-1mlamf20	146	18	have	have	VBP
cord-016871-1mlamf20	146	19	introduced	introduce	VBN
cord-016871-1mlamf20	146	20	a	a	DT
cord-016871-1mlamf20	146	21	maximum	maximum	JJ
cord-016871-1mlamf20	146	22	storage	storage	NN
cord-016871-1mlamf20	146	23	time	time	NN
cord-016871-1mlamf20	146	24	of	of	IN
cord-016871-1mlamf20	146	25	7	7	CD
cord-016871-1mlamf20	146	26	days	day	NNS
cord-016871-1mlamf20	146	27	for	for	IN
cord-016871-1mlamf20	146	28	nonfrozen	nonfrozen	NN
cord-016871-1mlamf20	146	29	plasma	plasma	NN
cord-016871-1mlamf20	146	30	[	[	-LRB-
cord-016871-1mlamf20	146	31	37	37	CD
cord-016871-1mlamf20	146	32	]	]	-RRB-
cord-016871-1mlamf20	146	33	.	.	.
cord-016871-1mlamf20	147	1	Murad	Murad	NNP
cord-016871-1mlamf20	147	2	et	et	NNP
cord-016871-1mlamf20	147	3	al	al	NNP
cord-016871-1mlamf20	147	4	.	.	.
cord-016871-1mlamf20	148	1	's	's	POS
cord-016871-1mlamf20	149	1	meta	meta	NNP
cord-016871-1mlamf20	149	2	-	-	HYPH
cord-016871-1mlamf20	149	3	analysis	analysis	NN
cord-016871-1mlamf20	149	4	of	of	IN
cord-016871-1mlamf20	149	5	37	37	CD
cord-016871-1mlamf20	149	6	studies	study	NNS
cord-016871-1mlamf20	149	7	on	on	IN
cord-016871-1mlamf20	149	8	adults	adult	NNS
cord-016871-1mlamf20	149	9	transfused	transfuse	VBN
cord-016871-1mlamf20	149	10	with	with	IN
cord-016871-1mlamf20	149	11	plasma	plasma	NN
cord-016871-1mlamf20	149	12	compared	compare	VBN
cord-016871-1mlamf20	149	13	with	with	IN
cord-016871-1mlamf20	149	14	nontransfused	nontransfused	JJ
cord-016871-1mlamf20	149	15	controls	control	NNS
cord-016871-1mlamf20	149	16	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	149	17	that	that	IN
cord-016871-1mlamf20	149	18	in	in	IN
cord-016871-1mlamf20	149	19	the	the	DT
cord-016871-1mlamf20	149	20	setting	setting	NN
cord-016871-1mlamf20	149	21	of	of	IN
cord-016871-1mlamf20	149	22	massive	massive	JJ
cord-016871-1mlamf20	149	23	transfusions	transfusion	NNS
cord-016871-1mlamf20	149	24	in	in	IN
cord-016871-1mlamf20	149	25	trauma	trauma	NN
cord-016871-1mlamf20	149	26	patients	patient	NNS
cord-016871-1mlamf20	149	27	,	,	,
cord-016871-1mlamf20	149	28	transfusion	transfusion	NN
cord-016871-1mlamf20	149	29	may	may	MD
cord-016871-1mlamf20	149	30	be	be	VB
cord-016871-1mlamf20	149	31	associated	associate	VBN
cord-016871-1mlamf20	149	32	with	with	IN
cord-016871-1mlamf20	149	33	increased	increase	VBN
cord-016871-1mlamf20	149	34	survival	survival	NN
cord-016871-1mlamf20	149	35	and	and	CC
cord-016871-1mlamf20	149	36	decreased	decrease	VBD
cord-016871-1mlamf20	149	37	multiorgan	multiorgan	NNP
cord-016871-1mlamf20	149	38	failure	failure	NN
cord-016871-1mlamf20	149	39	.	.	.
cord-016871-1mlamf20	150	1	However	however	RB
cord-016871-1mlamf20	150	2	,	,	,
cord-016871-1mlamf20	150	3	they	-PRON-	PRP
cord-016871-1mlamf20	150	4	also	also	RB
cord-016871-1mlamf20	150	5	noted	note	VBD
cord-016871-1mlamf20	150	6	increased	increased	JJ
cord-016871-1mlamf20	150	7	mortality	mortality	NN
cord-016871-1mlamf20	150	8	in	in	IN
cord-016871-1mlamf20	150	9	patients	patient	NNS
cord-016871-1mlamf20	150	10	who	who	WP
cord-016871-1mlamf20	150	11	received	receive	VBD
cord-016871-1mlamf20	150	12	plasma	plasma	NN
cord-016871-1mlamf20	150	13	not	not	RB
cord-016871-1mlamf20	150	14	part	part	NN
cord-016871-1mlamf20	150	15	of	of	IN
cord-016871-1mlamf20	150	16	a	a	DT
cord-016871-1mlamf20	150	17	massive	massive	JJ
cord-016871-1mlamf20	150	18	transfusion	transfusion	NN
cord-016871-1mlamf20	150	19	protocol	protocol	NN
cord-016871-1mlamf20	150	20	.	.	.
cord-016871-1mlamf20	151	1	This	this	DT
cord-016871-1mlamf20	151	2	fi	fi	IN
cord-016871-1mlamf20	151	3	nding	nding	NN
cord-016871-1mlamf20	151	4	may	may	MD
cord-016871-1mlamf20	151	5	be	be	VB
cord-016871-1mlamf20	151	6	due	due	JJ
cord-016871-1mlamf20	151	7	to	to	IN
cord-016871-1mlamf20	151	8	the	the	DT
cord-016871-1mlamf20	151	9	unbalanced	unbalanced	JJ
cord-016871-1mlamf20	151	10	ratio	ratio	NN
cord-016871-1mlamf20	151	11	of	of	IN
cord-016871-1mlamf20	151	12	transfusion	transfusion	NN
cord-016871-1mlamf20	151	13	of	of	IN
cord-016871-1mlamf20	151	14	products	product	NNS
cord-016871-1mlamf20	151	15	,	,	,
cord-016871-1mlamf20	151	16	unlike	unlike	IN
cord-016871-1mlamf20	151	17	in	in	IN
cord-016871-1mlamf20	151	18	mass	mass	JJ
cord-016871-1mlamf20	151	19	transfusion	transfusion	NN
cord-016871-1mlamf20	151	20	protocols	protocol	NNS
cord-016871-1mlamf20	151	21	,	,	,
cord-016871-1mlamf20	151	22	which	which	WDT
cord-016871-1mlamf20	151	23	call	call	VBP
cord-016871-1mlamf20	151	24	for	for	IN
cord-016871-1mlamf20	151	25	1:1	1:1	CD
cord-016871-1mlamf20	151	26	transfusion	transfusion	NN
cord-016871-1mlamf20	151	27	of	of	IN
cord-016871-1mlamf20	151	28	RBCs	rbc	NNS
cord-016871-1mlamf20	151	29	and	and	CC
cord-016871-1mlamf20	151	30	plasma	plasma	NN
cord-016871-1mlamf20	151	31	.	.	.
cord-016871-1mlamf20	152	1	In	in	IN
cord-016871-1mlamf20	152	2	addition	addition	NN
cord-016871-1mlamf20	152	3	,	,	,
cord-016871-1mlamf20	152	4	plasma	plasma	NN
cord-016871-1mlamf20	152	5	transfusion	transfusion	NN
cord-016871-1mlamf20	152	6	was	be	VBD
cord-016871-1mlamf20	152	7	associated	associate	VBN
cord-016871-1mlamf20	152	8	with	with	IN
cord-016871-1mlamf20	152	9	increased	increase	VBN
cord-016871-1mlamf20	152	10	risk	risk	NN
cord-016871-1mlamf20	152	11	of	of	IN
cord-016871-1mlamf20	152	12	developing	develop	VBG
cord-016871-1mlamf20	152	13	TRALI	TRALI	NNP
cord-016871-1mlamf20	152	14	,	,	,
cord-016871-1mlamf20	152	15	and	and	CC
cord-016871-1mlamf20	152	16	by	by	IN
cord-016871-1mlamf20	152	17	itself	-PRON-	PRP
cord-016871-1mlamf20	152	18	did	do	VBD
cord-016871-1mlamf20	152	19	not	not	RB
cord-016871-1mlamf20	152	20	reduce	reduce	VB
cord-016871-1mlamf20	152	21	transfusion	transfusion	NN
cord-016871-1mlamf20	152	22	requirements	requirement	NNS
cord-016871-1mlamf20	152	23	[	[	-LRB-
cord-016871-1mlamf20	152	24	34	34	CD
cord-016871-1mlamf20	152	25	]	]	-RRB-
cord-016871-1mlamf20	152	26	.	.	.
cord-016871-1mlamf20	153	1	Their	-PRON-	PRP$
cord-016871-1mlamf20	153	2	fi	fi	NN
cord-016871-1mlamf20	153	3	ndings	nding	NNS
cord-016871-1mlamf20	153	4	,	,	,
cord-016871-1mlamf20	153	5	in	in	IN
cord-016871-1mlamf20	153	6	the	the	DT
cord-016871-1mlamf20	153	7	fi	fi	NNP
cord-016871-1mlamf20	153	8	rst	rst	NNP
cord-016871-1mlamf20	153	9	comprehensive	comprehensive	JJ
cord-016871-1mlamf20	153	10	meta	meta	NNP
cord-016871-1mlamf20	153	11	-	-	HYPH
cord-016871-1mlamf20	153	12	analysis	analysis	NN
cord-016871-1mlamf20	153	13	and	and	CC
cord-016871-1mlamf20	153	14	systematic	systematic	JJ
cord-016871-1mlamf20	153	15	review	review	NN
cord-016871-1mlamf20	153	16	of	of	IN
cord-016871-1mlamf20	153	17	plasma	plasma	NN
cord-016871-1mlamf20	153	18	transfusion	transfusion	NN
cord-016871-1mlamf20	153	19	outcomes	outcome	NNS
cord-016871-1mlamf20	153	20	,	,	,
cord-016871-1mlamf20	153	21	highlight	highlight	VBP
cord-016871-1mlamf20	153	22	the	the	DT
cord-016871-1mlamf20	153	23	need	need	NN
cord-016871-1mlamf20	153	24	of	of	IN
cord-016871-1mlamf20	153	25	assessing	assess	VBG
cord-016871-1mlamf20	153	26	each	each	DT
cord-016871-1mlamf20	153	27	patient	patient	NN
cord-016871-1mlamf20	153	28	's	's	POS
cord-016871-1mlamf20	153	29	indications	indication	NNS
cord-016871-1mlamf20	153	30	for	for	IN
cord-016871-1mlamf20	153	31	plasma	plasma	NN
cord-016871-1mlamf20	153	32	.	.	.
cord-016871-1mlamf20	154	1	The	the	DT
cord-016871-1mlamf20	154	2	maturation	maturation	NN
cord-016871-1mlamf20	154	3	of	of	IN
cord-016871-1mlamf20	154	4	this	this	DT
cord-016871-1mlamf20	154	5	fi	fi	NNP
cord-016871-1mlamf20	154	6	eld	eld	NNP
cord-016871-1mlamf20	154	7	will	will	MD
cord-016871-1mlamf20	154	8	be	be	VB
cord-016871-1mlamf20	154	9	needed	need	VBN
cord-016871-1mlamf20	154	10	to	to	TO
cord-016871-1mlamf20	154	11	strengthen	strengthen	VB
cord-016871-1mlamf20	154	12	the	the	DT
cord-016871-1mlamf20	154	13	fi	fi	NNP
cord-016871-1mlamf20	154	14	ndings	nding	NNS
cord-016871-1mlamf20	154	15	,	,	,
cord-016871-1mlamf20	154	16	which	which	WDT
cord-016871-1mlamf20	154	17	the	the	DT
cord-016871-1mlamf20	154	18	authors	author	NNS
cord-016871-1mlamf20	154	19	did	do	VBD
cord-016871-1mlamf20	154	20	note	note	VB
cord-016871-1mlamf20	154	21	were	be	VBD
cord-016871-1mlamf20	154	22	subject	subject	JJ
cord-016871-1mlamf20	154	23	to	to	IN
cord-016871-1mlamf20	154	24	survivor	survivor	NN
cord-016871-1mlamf20	154	25	biases	bias	NNS
cord-016871-1mlamf20	154	26	in	in	IN
cord-016871-1mlamf20	154	27	some	some	DT
cord-016871-1mlamf20	154	28	studies	study	NNS
cord-016871-1mlamf20	154	29	.	.	.
cord-016871-1mlamf20	155	1	However	however	RB
cord-016871-1mlamf20	155	2	,	,	,
cord-016871-1mlamf20	155	3	none	none	NN
cord-016871-1mlamf20	155	4	of	of	IN
cord-016871-1mlamf20	155	5	these	these	DT
cord-016871-1mlamf20	155	6	studies	study	NNS
cord-016871-1mlamf20	155	7	involved	involve	VBD
cord-016871-1mlamf20	155	8	the	the	DT
cord-016871-1mlamf20	155	9	use	use	NN
cord-016871-1mlamf20	155	10	of	of	IN
cord-016871-1mlamf20	155	11	plasma	plasma	NN
cord-016871-1mlamf20	155	12	in	in	IN
cord-016871-1mlamf20	155	13	patients	patient	NNS
cord-016871-1mlamf20	155	14	with	with	IN
cord-016871-1mlamf20	155	15	hemorrhagic	hemorrhagic	JJ
cord-016871-1mlamf20	155	16	shock	shock	NN
cord-016871-1mlamf20	155	17	.	.	.
cord-016871-1mlamf20	156	1	In	in	IN
cord-016871-1mlamf20	156	2	this	this	DT
cord-016871-1mlamf20	156	3	population	population	NN
cord-016871-1mlamf20	156	4	of	of	IN
cord-016871-1mlamf20	156	5	patients	patient	NNS
cord-016871-1mlamf20	156	6	,	,	,
cord-016871-1mlamf20	156	7	the	the	DT
cord-016871-1mlamf20	156	8	incidence	incidence	NN
cord-016871-1mlamf20	156	9	of	of	IN
cord-016871-1mlamf20	156	10	multi	multi	JJ
cord-016871-1mlamf20	156	11	-	-	JJ
cord-016871-1mlamf20	156	12	organ	organ	JJ
cord-016871-1mlamf20	156	13	failure	failure	NN
cord-016871-1mlamf20	156	14	has	have	VBZ
cord-016871-1mlamf20	156	15	been	be	VBN
cord-016871-1mlamf20	156	16	shown	show	VBN
cord-016871-1mlamf20	156	17	to	to	TO
cord-016871-1mlamf20	156	18	be	be	VB
cord-016871-1mlamf20	156	19	lower	low	JJR
cord-016871-1mlamf20	156	20	than	than	IN
cord-016871-1mlamf20	156	21	comparison	comparison	NN
cord-016871-1mlamf20	156	22	cohorts	cohort	NNS
cord-016871-1mlamf20	156	23	(	(	-LRB-
cord-016871-1mlamf20	156	24	most	most	RBS
cord-016871-1mlamf20	156	25	likely	likely	JJ
cord-016871-1mlamf20	156	26	as	as	IN
cord-016871-1mlamf20	156	27	a	a	DT
cord-016871-1mlamf20	156	28	result	result	NN
cord-016871-1mlamf20	156	29	of	of	IN
cord-016871-1mlamf20	156	30	less	less	JJR
cord-016871-1mlamf20	156	31	overall	overall	JJ
cord-016871-1mlamf20	156	32	transfusions	transfusion	NNS
cord-016871-1mlamf20	156	33	in	in	IN
cord-016871-1mlamf20	156	34	the	the	DT
cord-016871-1mlamf20	156	35	higher	high	JJR
cord-016871-1mlamf20	156	36	plasma	plasma	NN
cord-016871-1mlamf20	156	37	group	group	NN
cord-016871-1mlamf20	156	38	)	)	-RRB-
cord-016871-1mlamf20	156	39	[	[	-LRB-
cord-016871-1mlamf20	156	40	13	13	CD
cord-016871-1mlamf20	156	41	,	,	,
cord-016871-1mlamf20	156	42	14	14	CD
cord-016871-1mlamf20	156	43	]	]	-RRB-
cord-016871-1mlamf20	156	44	.	.	.
cord-016871-1mlamf20	157	1	The	the	DT
cord-016871-1mlamf20	157	2	purpose	purpose	NN
cord-016871-1mlamf20	157	3	of	of	IN
cord-016871-1mlamf20	157	4	platelet	platelet	NN
cord-016871-1mlamf20	157	5	transfusions	transfusion	NNS
cord-016871-1mlamf20	157	6	is	be	VBZ
cord-016871-1mlamf20	157	7	to	to	TO
cord-016871-1mlamf20	157	8	avoid	avoid	VB
cord-016871-1mlamf20	157	9	spontaneous	spontaneous	JJ
cord-016871-1mlamf20	157	10	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	157	11	,	,	,
cord-016871-1mlamf20	157	12	which	which	WDT
cord-016871-1mlamf20	157	13	can	can	MD
cord-016871-1mlamf20	157	14	occur	occur	VB
cord-016871-1mlamf20	157	15	at	at	IN
cord-016871-1mlamf20	157	16	very	very	RB
cord-016871-1mlamf20	157	17	low	low	JJ
cord-016871-1mlamf20	157	18	platelet	platelet	NN
cord-016871-1mlamf20	157	19	levels	level	NNS
cord-016871-1mlamf20	157	20	,	,	,
cord-016871-1mlamf20	157	21	especially	especially	RB
cord-016871-1mlamf20	157	22	in	in	IN
cord-016871-1mlamf20	157	23	patients	patient	NNS
cord-016871-1mlamf20	157	24	who	who	WP
cord-016871-1mlamf20	157	25	are	be	VBP
cord-016871-1mlamf20	157	26	already	already	RB
cord-016871-1mlamf20	157	27	hemorrhaging	hemorrhage	VBG
cord-016871-1mlamf20	157	28	or	or	CC
cord-016871-1mlamf20	157	29	have	have	VBP
cord-016871-1mlamf20	157	30	various	various	JJ
cord-016871-1mlamf20	157	31	platelet	platelet	NN
cord-016871-1mlamf20	157	32	de	de	FW
cord-016871-1mlamf20	157	33	fi	fi	FW
cord-016871-1mlamf20	157	34	ciencies	ciencie	NNS
cord-016871-1mlamf20	157	35	and	and	CC
cord-016871-1mlamf20	157	36	abnormalities	abnormality	NNS
cord-016871-1mlamf20	157	37	of	of	IN
cord-016871-1mlamf20	157	38	function	function	NN
cord-016871-1mlamf20	157	39	.	.	.
cord-016871-1mlamf20	158	1	Along	along	IN
cord-016871-1mlamf20	158	2	with	with	IN
cord-016871-1mlamf20	158	3	plasma	plasma	NN
cord-016871-1mlamf20	158	4	and	and	CC
cord-016871-1mlamf20	158	5	fi	fi	NNP
cord-016871-1mlamf20	158	6	brinogen	brinogen	NNP
cord-016871-1mlamf20	158	7	,	,	,
cord-016871-1mlamf20	158	8	platelets	platelet	NNS
cord-016871-1mlamf20	158	9	are	be	VBP
cord-016871-1mlamf20	158	10	key	key	JJ
cord-016871-1mlamf20	158	11	in	in	IN
cord-016871-1mlamf20	158	12	achieving	achieve	VBG
cord-016871-1mlamf20	158	13	hemostasis	hemostasis	NN
cord-016871-1mlamf20	158	14	in	in	IN
cord-016871-1mlamf20	158	15	the	the	DT
cord-016871-1mlamf20	158	16	obstetric	obstetric	JJ
cord-016871-1mlamf20	158	17	patient	patient	NN
cord-016871-1mlamf20	158	18	with	with	IN
cord-016871-1mlamf20	158	19	post	post	JJ
cord-016871-1mlamf20	158	20	-	-	JJ
cord-016871-1mlamf20	158	21	partum	partum	JJ
cord-016871-1mlamf20	158	22	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	158	23	[	[	-LRB-
cord-016871-1mlamf20	158	24	38	38	CD
cord-016871-1mlamf20	158	25	]	]	-RRB-
cord-016871-1mlamf20	158	26	.	.	.
cord-016871-1mlamf20	159	1	Approximately	approximately	RB
cord-016871-1mlamf20	159	2	50,000	50,000	CD
cord-016871-1mlamf20	159	3	cells/	cells/	CD
cord-016871-1mlamf20	160	1	L	l	NN
cord-016871-1mlamf20	160	2	of	of	IN
cord-016871-1mlamf20	160	3	platelets	platelet	NNS
cord-016871-1mlamf20	160	4	are	be	VBP
cord-016871-1mlamf20	160	5	necessary	necessary	JJ
cord-016871-1mlamf20	160	6	in	in	IN
cord-016871-1mlamf20	160	7	order	order	NN
cord-016871-1mlamf20	160	8	to	to	TO
cord-016871-1mlamf20	160	9	achieve	achieve	VB
cord-016871-1mlamf20	160	10	adequate	adequate	JJ
cord-016871-1mlamf20	160	11	hemostasis	hemostasis	NN
cord-016871-1mlamf20	160	12	.	.	.
cord-016871-1mlamf20	161	1	In	in	IN
cord-016871-1mlamf20	161	2	addition	addition	NN
cord-016871-1mlamf20	161	3	to	to	IN
cord-016871-1mlamf20	161	4	the	the	DT
cord-016871-1mlamf20	161	5	total	total	JJ
cord-016871-1mlamf20	161	6	number	number	NN
cord-016871-1mlamf20	161	7	of	of	IN
cord-016871-1mlamf20	161	8	platelets	platelet	NNS
cord-016871-1mlamf20	161	9	,	,	,
cord-016871-1mlamf20	161	10	their	-PRON-	PRP$
cord-016871-1mlamf20	161	11	quality	quality	NN
cord-016871-1mlamf20	161	12	is	be	VBZ
cord-016871-1mlamf20	161	13	also	also	RB
cord-016871-1mlamf20	161	14	important	important	JJ
cord-016871-1mlamf20	161	15	to	to	IN
cord-016871-1mlamf20	161	16	overall	overall	JJ
cord-016871-1mlamf20	161	17	hemostatic	hemostatic	JJ
cord-016871-1mlamf20	161	18	function	function	NN
cord-016871-1mlamf20	161	19	.	.	.
cord-016871-1mlamf20	162	1	A	a	DT
cord-016871-1mlamf20	162	2	patient	patient	NN
cord-016871-1mlamf20	162	3	's	's	POS
cord-016871-1mlamf20	162	4	platelets	platelet	NNS
cord-016871-1mlamf20	162	5	must	must	MD
cord-016871-1mlamf20	162	6	be	be	VB
cord-016871-1mlamf20	162	7	ef	ef	NNP
cord-016871-1mlamf20	162	8	fi	fi	NNP
cord-016871-1mlamf20	162	9	cacious	cacious	NNP
cord-016871-1mlamf20	162	10	,	,	,
cord-016871-1mlamf20	162	11	that	that	RB
cord-016871-1mlamf20	162	12	is	is	RB
cord-016871-1mlamf20	162	13	,	,	,
cord-016871-1mlamf20	162	14	remaining	remain	VBG
cord-016871-1mlamf20	162	15	in	in	IN
cord-016871-1mlamf20	162	16	circulation	circulation	NN
cord-016871-1mlamf20	162	17	and	and	CC
cord-016871-1mlamf20	162	18	completing	complete	VBG
cord-016871-1mlamf20	162	19	its	-PRON-	PRP$
cord-016871-1mlamf20	162	20	physiological	physiological	JJ
cord-016871-1mlamf20	162	21	role	role	NN
cord-016871-1mlamf20	162	22	in	in	IN
cord-016871-1mlamf20	162	23	clot	clot	NN
cord-016871-1mlamf20	162	24	formation	formation	NN
cord-016871-1mlamf20	162	25	[	[	-LRB-
cord-016871-1mlamf20	162	26	39	39	CD
cord-016871-1mlamf20	162	27	]	]	-RRB-
cord-016871-1mlamf20	162	28	.	.	.
cord-016871-1mlamf20	163	1	This	this	DT
cord-016871-1mlamf20	163	2	ef	ef	NNP
cord-016871-1mlamf20	163	3	fi	fi	NN
cord-016871-1mlamf20	163	4	cacy	cacy	NN
cord-016871-1mlamf20	163	5	can	can	MD
cord-016871-1mlamf20	163	6	be	be	VB
cord-016871-1mlamf20	163	7	assessed	assess	VBN
cord-016871-1mlamf20	163	8	by	by	IN
cord-016871-1mlamf20	163	9	various	various	JJ
cord-016871-1mlamf20	163	10	modalities	modality	NNS
cord-016871-1mlamf20	163	11	,	,	,
cord-016871-1mlamf20	163	12	from	from	IN
cord-016871-1mlamf20	163	13	the	the	DT
cord-016871-1mlamf20	163	14	traditional	traditional	JJ
cord-016871-1mlamf20	163	15	laboratory	laboratory	NN
cord-016871-1mlamf20	163	16	coagulation	coagulation	NN
cord-016871-1mlamf20	163	17	studies	study	NNS
cord-016871-1mlamf20	163	18	to	to	IN
cord-016871-1mlamf20	163	19	the	the	DT
cord-016871-1mlamf20	163	20	more	more	RBR
cord-016871-1mlamf20	163	21	recent	recent	JJ
cord-016871-1mlamf20	163	22	thrombelastograms	thrombelastogram	NNS
cord-016871-1mlamf20	163	23	(	(	-LRB-
cord-016871-1mlamf20	163	24	TEG	TEG	NNP
cord-016871-1mlamf20	163	25	)	)	-RRB-
cord-016871-1mlamf20	163	26	,	,	,
cord-016871-1mlamf20	163	27	also	also	RB
cord-016871-1mlamf20	163	28	known	know	VBN
cord-016871-1mlamf20	163	29	as	as	IN
cord-016871-1mlamf20	163	30	thromboelastography	thromboelastography	NNP
cord-016871-1mlamf20	163	31	,	,	,
cord-016871-1mlamf20	163	32	and	and	CC
cord-016871-1mlamf20	163	33	this	this	DT
cord-016871-1mlamf20	163	34	topic	topic	NN
cord-016871-1mlamf20	163	35	is	be	VBZ
cord-016871-1mlamf20	163	36	covered	cover	VBN
cord-016871-1mlamf20	163	37	in	in	IN
cord-016871-1mlamf20	163	38	the	the	DT
cord-016871-1mlamf20	163	39	last	last	JJ
cord-016871-1mlamf20	163	40	section	section	NN
cord-016871-1mlamf20	163	41	.	.	.
cord-016871-1mlamf20	164	1	Cryoprecipitate	Cryoprecipitate	NNP
cord-016871-1mlamf20	164	2	consists	consist	VBZ
cord-016871-1mlamf20	164	3	of	of	IN
cord-016871-1mlamf20	164	4	von	von	NNP
cord-016871-1mlamf20	164	5	Willebrand	Willebrand	NNP
cord-016871-1mlamf20	164	6	factor	factor	NN
cord-016871-1mlamf20	164	7	/	/	SYM
cord-016871-1mlamf20	164	8	VIII	VIII	NNP
cord-016871-1mlamf20	164	9	complex	complex	NN
cord-016871-1mlamf20	164	10	,	,	,
cord-016871-1mlamf20	164	11	factor	factor	NN
cord-016871-1mlamf20	164	12	XIII	XIII	NNP
cord-016871-1mlamf20	164	13	,	,	,
cord-016871-1mlamf20	164	14	and	and	CC
cord-016871-1mlamf20	164	15	fi	fi	NNP
cord-016871-1mlamf20	164	16	brinogen	brinogen	NNP
cord-016871-1mlamf20	164	17	.	.	.
cord-016871-1mlamf20	165	1	It	-PRON-	PRP
cord-016871-1mlamf20	165	2	is	be	VBZ
cord-016871-1mlamf20	165	3	used	use	VBN
cord-016871-1mlamf20	165	4	to	to	TO
cord-016871-1mlamf20	165	5	supplement	supplement	VB
cord-016871-1mlamf20	165	6	plasma	plasma	NN
cord-016871-1mlamf20	165	7	transfusions	transfusion	NNS
cord-016871-1mlamf20	165	8	with	with	IN
cord-016871-1mlamf20	165	9	fi	fi	NNP
cord-016871-1mlamf20	165	10	brinogen	brinogen	NNP
cord-016871-1mlamf20	165	11	,	,	,
cord-016871-1mlamf20	165	12	especially	especially	RB
cord-016871-1mlamf20	165	13	in	in	IN
cord-016871-1mlamf20	165	14	patients	patient	NNS
cord-016871-1mlamf20	165	15	with	with	IN
cord-016871-1mlamf20	165	16	fi	fi	NNP
cord-016871-1mlamf20	165	17	brinogen	brinogen	NNP
cord-016871-1mlamf20	165	18	levels	level	NNS
cord-016871-1mlamf20	165	19	of	of	IN
cord-016871-1mlamf20	165	20	less	less	JJR
cord-016871-1mlamf20	165	21	than	than	IN
cord-016871-1mlamf20	165	22	100	100	CD
cord-016871-1mlamf20	165	23	mg	mg	NNP
cord-016871-1mlamf20	165	24	/	/	SYM
cord-016871-1mlamf20	165	25	dL	dl	NN
cord-016871-1mlamf20	165	26	,	,	,
cord-016871-1mlamf20	165	27	the	the	DT
cord-016871-1mlamf20	165	28	level	level	NN
cord-016871-1mlamf20	165	29	at	at	IN
cord-016871-1mlamf20	165	30	which	which	WDT
cord-016871-1mlamf20	165	31	hypo	hypo	NN
cord-016871-1mlamf20	165	32	fi	fi	NNP
cord-016871-1mlamf20	165	33	brinogenemia	brinogenemia	NN
cord-016871-1mlamf20	165	34	results	result	VBZ
cord-016871-1mlamf20	165	35	in	in	IN
cord-016871-1mlamf20	165	36	bleeding	bleed	VBG
cord-016871-1mlamf20	165	37	[	[	-LRB-
cord-016871-1mlamf20	165	38	5	5	CD
cord-016871-1mlamf20	165	39	]	]	-RRB-
cord-016871-1mlamf20	165	40	.	.	.
cord-016871-1mlamf20	166	1	It	-PRON-	PRP
cord-016871-1mlamf20	166	2	is	be	VBZ
cord-016871-1mlamf20	166	3	named	name	VBN
cord-016871-1mlamf20	166	4	cryoprecipitate	cryoprecipitate	NNP
cord-016871-1mlamf20	166	5	because	because	IN
cord-016871-1mlamf20	166	6	single	single	JJ
cord-016871-1mlamf20	166	7	units	unit	NNS
cord-016871-1mlamf20	166	8	of	of	IN
cord-016871-1mlamf20	166	9	plasma	plasma	NN
cord-016871-1mlamf20	166	10	are	be	VBP
cord-016871-1mlamf20	166	11	rapidly	rapidly	RB
cord-016871-1mlamf20	166	12	frozen	freeze	VBN
cord-016871-1mlamf20	166	13	to	to	IN
cord-016871-1mlamf20	166	14	−30	−30	NNP
cord-016871-1mlamf20	166	15	°	°	NN
cord-016871-1mlamf20	166	16	C	c	NN
cord-016871-1mlamf20	166	17	and	and	CC
cord-016871-1mlamf20	166	18	are	be	VBP
cord-016871-1mlamf20	166	19	slowly	slowly	RB
cord-016871-1mlamf20	166	20	thawed	thaw	VBN
cord-016871-1mlamf20	166	21	overnight	overnight	RB
cord-016871-1mlamf20	166	22	to	to	IN
cord-016871-1mlamf20	166	23	4	4	CD
cord-016871-1mlamf20	166	24	°	°	NN
cord-016871-1mlamf20	166	25	C	c	NN
cord-016871-1mlamf20	166	26	,	,	,
cord-016871-1mlamf20	166	27	causing	cause	VBG
cord-016871-1mlamf20	166	28	many	many	JJ
cord-016871-1mlamf20	166	29	clotting	clotting	NN
cord-016871-1mlamf20	166	30	factors	factor	NNS
cord-016871-1mlamf20	166	31	such	such	JJ
cord-016871-1mlamf20	166	32	as	as	IN
cord-016871-1mlamf20	166	33	fi	fi	NNP
cord-016871-1mlamf20	166	34	brinogen	brinogen	NNP
cord-016871-1mlamf20	166	35	to	to	TO
cord-016871-1mlamf20	166	36	precipitate	precipitate	VB
cord-016871-1mlamf20	166	37	out	out	IN
cord-016871-1mlamf20	166	38	of	of	IN
cord-016871-1mlamf20	166	39	the	the	DT
cord-016871-1mlamf20	166	40	solution	solution	NN
cord-016871-1mlamf20	166	41	[	[	-LRB-
cord-016871-1mlamf20	166	42	35	35	CD
cord-016871-1mlamf20	166	43	]	]	-RRB-
cord-016871-1mlamf20	166	44	.	.	.
cord-016871-1mlamf20	167	1	Indications	indication	NNS
cord-016871-1mlamf20	167	2	for	for	IN
cord-016871-1mlamf20	167	3	cryoprecipitate	cryoprecipitate	NNP
cord-016871-1mlamf20	167	4	include	include	VBP
cord-016871-1mlamf20	167	5	factor	factor	NN
cord-016871-1mlamf20	167	6	VII	VII	NNP
cord-016871-1mlamf20	167	7	de	de	NNP
cord-016871-1mlamf20	167	8	fi	fi	NNP
cord-016871-1mlamf20	167	9	ciency	ciency	NN
cord-016871-1mlamf20	167	10	,	,	,
cord-016871-1mlamf20	167	11	congenital	congenital	JJ
cord-016871-1mlamf20	167	12	or	or	CC
cord-016871-1mlamf20	167	13	acquired	acquire	VBN
cord-016871-1mlamf20	167	14	hypo	hypo	NN
cord-016871-1mlamf20	167	15	fi	fi	NNP
cord-016871-1mlamf20	167	16	brinogenemia	brinogenemia	NN
cord-016871-1mlamf20	167	17	,	,	,
cord-016871-1mlamf20	167	18	disseminated	disseminate	VBN
cord-016871-1mlamf20	167	19	intravascular	intravascular	JJ
cord-016871-1mlamf20	167	20	coagulation	coagulation	NN
cord-016871-1mlamf20	167	21	,	,	,
cord-016871-1mlamf20	167	22	and	and	CC
cord-016871-1mlamf20	167	23	massive	massive	JJ
cord-016871-1mlamf20	167	24	transfusion	transfusion	NN
cord-016871-1mlamf20	167	25	.	.	.
cord-016871-1mlamf20	168	1	Unlike	unlike	IN
cord-016871-1mlamf20	168	2	plasma	plasma	NN
cord-016871-1mlamf20	168	3	,	,	,
cord-016871-1mlamf20	168	4	virus	virus	NN
cord-016871-1mlamf20	168	5	-	-	HYPH
cord-016871-1mlamf20	168	6	inactivated	inactivate	VBN
cord-016871-1mlamf20	168	7	cryoprecipitate	cryoprecipitate	NN
cord-016871-1mlamf20	168	8	is	be	VBZ
cord-016871-1mlamf20	168	9	not	not	RB
cord-016871-1mlamf20	168	10	yet	yet	RB
cord-016871-1mlamf20	168	11	available	available	JJ
cord-016871-1mlamf20	168	12	,	,	,
cord-016871-1mlamf20	168	13	and	and	CC
cord-016871-1mlamf20	168	14	studies	study	NNS
cord-016871-1mlamf20	168	15	on	on	IN
cord-016871-1mlamf20	168	16	the	the	DT
cord-016871-1mlamf20	168	17	ef	ef	NNP
cord-016871-1mlamf20	168	18	fi	fi	NN
cord-016871-1mlamf20	168	19	cacy	cacy	NN
cord-016871-1mlamf20	168	20	of	of	IN
cord-016871-1mlamf20	168	21	SD	SD	NNP
cord-016871-1mlamf20	168	22	FFP	FFP	NNP
cord-016871-1mlamf20	168	23	and	and	CC
cord-016871-1mlamf20	168	24	MB	MB	NNP
cord-016871-1mlamf20	168	25	FFP	FFP	NNP
cord-016871-1mlamf20	168	26	have	have	VBP
cord-016871-1mlamf20	168	27	not	not	RB
cord-016871-1mlamf20	168	28	shown	show	VBN
cord-016871-1mlamf20	168	29	a	a	DT
cord-016871-1mlamf20	168	30	bene	bene	NN
cord-016871-1mlamf20	168	31	fi	fi	NN
cord-016871-1mlamf20	168	32	t	t	NN
cord-016871-1mlamf20	168	33	[	[	-LRB-
cord-016871-1mlamf20	168	34	35	35	CD
cord-016871-1mlamf20	168	35	]	]	-RRB-
cord-016871-1mlamf20	168	36	.	.	.
cord-016871-1mlamf20	169	1	The	the	DT
cord-016871-1mlamf20	169	2	complications	complication	NNS
cord-016871-1mlamf20	169	3	of	of	IN
cord-016871-1mlamf20	169	4	cryoprecipitate	cryoprecipitate	NNP
cord-016871-1mlamf20	169	5	are	be	VBP
cord-016871-1mlamf20	169	6	similar	similar	JJ
cord-016871-1mlamf20	169	7	to	to	IN
cord-016871-1mlamf20	169	8	those	those	DT
cord-016871-1mlamf20	169	9	of	of	IN
cord-016871-1mlamf20	169	10	plasma	plasma	NN
cord-016871-1mlamf20	169	11	,	,	,
cord-016871-1mlamf20	169	12	with	with	IN
cord-016871-1mlamf20	169	13	a	a	DT
cord-016871-1mlamf20	169	14	slightly	slightly	RB
cord-016871-1mlamf20	169	15	lower	low	JJR
cord-016871-1mlamf20	169	16	occurrence	occurrence	NN
cord-016871-1mlamf20	169	17	of	of	IN
cord-016871-1mlamf20	169	18	complications	complication	NNS
cord-016871-1mlamf20	169	19	associated	associate	VBN
cord-016871-1mlamf20	169	20	with	with	IN
cord-016871-1mlamf20	169	21	higher	high	JJR
cord-016871-1mlamf20	169	22	volumes	volume	NNS
cord-016871-1mlamf20	169	23	of	of	IN
cord-016871-1mlamf20	169	24	plasma	plasma	NN
cord-016871-1mlamf20	169	25	,	,	,
cord-016871-1mlamf20	169	26	such	such	JJ
cord-016871-1mlamf20	169	27	as	as	IN
cord-016871-1mlamf20	169	28	TRALI	TRALI	NNP
cord-016871-1mlamf20	169	29	and	and	CC
cord-016871-1mlamf20	169	30	hemolysis	hemolysis	NN
cord-016871-1mlamf20	169	31	[	[	-LRB-
cord-016871-1mlamf20	169	32	35	35	CD
cord-016871-1mlamf20	169	33	]	]	-RRB-
cord-016871-1mlamf20	169	34	.	.	.
cord-016871-1mlamf20	170	1	The	the	DT
cord-016871-1mlamf20	170	2	practice	practice	NN
cord-016871-1mlamf20	170	3	of	of	IN
cord-016871-1mlamf20	170	4	using	use	VBG
cord-016871-1mlamf20	170	5	whole	whole	JJ
cord-016871-1mlamf20	170	6	blood	blood	NN
cord-016871-1mlamf20	170	7	is	be	VBZ
cord-016871-1mlamf20	170	8	largely	largely	RB
cord-016871-1mlamf20	170	9	uncommon	uncommon	JJ
cord-016871-1mlamf20	170	10	due	due	IN
cord-016871-1mlamf20	170	11	to	to	IN
cord-016871-1mlamf20	170	12	the	the	DT
cord-016871-1mlamf20	170	13	separation	separation	NN
cord-016871-1mlamf20	170	14	of	of	IN
cord-016871-1mlamf20	170	15	blood	blood	NN
cord-016871-1mlamf20	170	16	components	component	NNS
cord-016871-1mlamf20	170	17	for	for	IN
cord-016871-1mlamf20	170	18	targeting	target	VBG
cord-016871-1mlamf20	170	19	speci	speci	NNP
cord-016871-1mlamf20	170	20	fi	fi	NNP
cord-016871-1mlamf20	170	21	c	c	NN
cord-016871-1mlamf20	170	22	de	de	FW
cord-016871-1mlamf20	170	23	fi	fi	NNP
cord-016871-1mlamf20	170	24	ciencies	ciencies	NNP
cord-016871-1mlamf20	170	25	currently	currently	RB
cord-016871-1mlamf20	170	26	supported	support	VBN
cord-016871-1mlamf20	170	27	by	by	IN
cord-016871-1mlamf20	170	28	evidencebased	evidencebased	JJ
cord-016871-1mlamf20	170	29	medicine	medicine	NN
cord-016871-1mlamf20	170	30	.	.	.
cord-016871-1mlamf20	171	1	Decision	decision	NN
cord-016871-1mlamf20	171	2	-	-	HYPH
cord-016871-1mlamf20	171	3	making	making	NN
cord-016871-1mlamf20	171	4	for	for	IN
cord-016871-1mlamf20	171	5	each	each	DT
cord-016871-1mlamf20	171	6	transfusion	transfusion	NN
cord-016871-1mlamf20	171	7	requires	require	VBZ
cord-016871-1mlamf20	171	8	laboratory	laboratory	NN
cord-016871-1mlamf20	171	9	testing	testing	NN
cord-016871-1mlamf20	171	10	,	,	,
cord-016871-1mlamf20	171	11	and	and	CC
cord-016871-1mlamf20	171	12	each	each	DT
cord-016871-1mlamf20	171	13	product	product	NN
cord-016871-1mlamf20	171	14	must	must	MD
cord-016871-1mlamf20	171	15	carefully	carefully	RB
cord-016871-1mlamf20	171	16	be	be	VB
cord-016871-1mlamf20	171	17	stored	store	VBN
cord-016871-1mlamf20	171	18	and	and	CC
cord-016871-1mlamf20	171	19	transported	transport	VBN
cord-016871-1mlamf20	171	20	to	to	IN
cord-016871-1mlamf20	171	21	the	the	DT
cord-016871-1mlamf20	171	22	site	site	NN
cord-016871-1mlamf20	171	23	of	of	IN
cord-016871-1mlamf20	171	24	need	need	NN
cord-016871-1mlamf20	171	25	.	.	.
cord-016871-1mlamf20	172	1	When	when	WRB
cord-016871-1mlamf20	172	2	this	this	DT
cord-016871-1mlamf20	172	3	is	be	VBZ
cord-016871-1mlamf20	172	4	not	not	RB
cord-016871-1mlamf20	172	5	possible	possible	JJ
cord-016871-1mlamf20	172	6	,	,	,
cord-016871-1mlamf20	172	7	such	such	JJ
cord-016871-1mlamf20	172	8	as	as	IN
cord-016871-1mlamf20	172	9	in	in	IN
cord-016871-1mlamf20	172	10	acute	acute	JJ
cord-016871-1mlamf20	172	11	settings	setting	NNS
cord-016871-1mlamf20	172	12	with	with	IN
cord-016871-1mlamf20	172	13	limited	limited	JJ
cord-016871-1mlamf20	172	14	resources	resource	NNS
cord-016871-1mlamf20	172	15	,	,	,
cord-016871-1mlamf20	172	16	whole	whole	JJ
cord-016871-1mlamf20	172	17	blood	blood	NN
cord-016871-1mlamf20	172	18	transfusions	transfusion	NNS
cord-016871-1mlamf20	172	19	can	can	MD
cord-016871-1mlamf20	172	20	adequately	adequately	RB
cord-016871-1mlamf20	172	21	resuscitate	resuscitate	VB
cord-016871-1mlamf20	172	22	certain	certain	JJ
cord-016871-1mlamf20	172	23	patients	patient	NNS
cord-016871-1mlamf20	172	24	.	.	.
cord-016871-1mlamf20	173	1	Grosso	Grosso	NNP
cord-016871-1mlamf20	173	2	et	et	NNP
cord-016871-1mlamf20	173	3	al	al	NNP
cord-016871-1mlamf20	173	4	.	.	.
cord-016871-1mlamf20	174	1	recount	recount	VB
cord-016871-1mlamf20	174	2	a	a	DT
cord-016871-1mlamf20	174	3	case	case	NN
cord-016871-1mlamf20	174	4	of	of	IN
cord-016871-1mlamf20	174	5	collecting	collect	VBG
cord-016871-1mlamf20	174	6	whole	whole	JJ
cord-016871-1mlamf20	174	7	blood	blood	NN
cord-016871-1mlamf20	174	8	from	from	IN
cord-016871-1mlamf20	174	9	hospital	hospital	NN
cord-016871-1mlamf20	174	10	personnel	personnel	NNS
cord-016871-1mlamf20	174	11	donors	donor	NNS
cord-016871-1mlamf20	174	12	in	in	IN
cord-016871-1mlamf20	174	13	a	a	DT
cord-016871-1mlamf20	174	14	US	US	NNP
cord-016871-1mlamf20	174	15	fi	fi	NN
cord-016871-1mlamf20	174	16	eld	eld	NN
cord-016871-1mlamf20	174	17	surgical	surgical	JJ
cord-016871-1mlamf20	174	18	hospital	hospital	NN
cord-016871-1mlamf20	174	19	in	in	IN
cord-016871-1mlamf20	174	20	Kosovo	Kosovo	NNP
cord-016871-1mlamf20	174	21	[	[	-LRB-
cord-016871-1mlamf20	174	22	40	40	CD
cord-016871-1mlamf20	174	23	]	]	-RRB-
cord-016871-1mlamf20	174	24	.	.	.
cord-016871-1mlamf20	175	1	This	this	DT
cord-016871-1mlamf20	175	2	whole	whole	JJ
cord-016871-1mlamf20	175	3	blood	blood	NN
cord-016871-1mlamf20	175	4	was	be	VBD
cord-016871-1mlamf20	175	5	used	use	VBN
cord-016871-1mlamf20	175	6	to	to	TO
cord-016871-1mlamf20	175	7	treat	treat	VB
cord-016871-1mlamf20	175	8	exsanguinating	exsanguinate	VBG
cord-016871-1mlamf20	175	9	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	175	10	in	in	IN
cord-016871-1mlamf20	175	11	an	an	DT
cord-016871-1mlamf20	175	12	acutely	acutely	RB
cord-016871-1mlamf20	175	13	bleeding	bleeding	JJ
cord-016871-1mlamf20	175	14	patient	patient	NN
cord-016871-1mlamf20	175	15	.	.	.
cord-016871-1mlamf20	176	1	The	the	DT
cord-016871-1mlamf20	176	2	advantage	advantage	NN
cord-016871-1mlamf20	176	3	of	of	IN
cord-016871-1mlamf20	176	4	whole	whole	JJ
cord-016871-1mlamf20	176	5	blood	blood	NN
cord-016871-1mlamf20	176	6	is	be	VBZ
cord-016871-1mlamf20	176	7	its	-PRON-	PRP$
cord-016871-1mlamf20	176	8	ability	ability	NN
cord-016871-1mlamf20	176	9	to	to	TO
cord-016871-1mlamf20	176	10	increase	increase	VB
cord-016871-1mlamf20	176	11	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	176	12	levels	level	NNS
cord-016871-1mlamf20	176	13	,	,	,
cord-016871-1mlamf20	176	14	similarly	similarly	RB
cord-016871-1mlamf20	176	15	to	to	IN
cord-016871-1mlamf20	176	16	red	red	JJ
cord-016871-1mlamf20	176	17	blood	blood	NN
cord-016871-1mlamf20	176	18	cells	cell	NNS
cord-016871-1mlamf20	176	19	,	,	,
cord-016871-1mlamf20	176	20	and	and	CC
cord-016871-1mlamf20	176	21	its	-PRON-	PRP$
cord-016871-1mlamf20	176	22	ability	ability	NN
cord-016871-1mlamf20	176	23	to	to	TO
cord-016871-1mlamf20	176	24	restore	restore	VB
cord-016871-1mlamf20	176	25	blood	blood	NN
cord-016871-1mlamf20	176	26	volumes	volume	NNS
cord-016871-1mlamf20	176	27	,	,	,
cord-016871-1mlamf20	176	28	similarly	similarly	RB
cord-016871-1mlamf20	176	29	to	to	IN
cord-016871-1mlamf20	176	30	crystalloids	crystalloids	NNP
cord-016871-1mlamf20	176	31	[	[	-LRB-
cord-016871-1mlamf20	176	32	40	40	CD
cord-016871-1mlamf20	176	33	]	]	-RRB-
cord-016871-1mlamf20	176	34	.	.	.
cord-016871-1mlamf20	177	1	Because	because	IN
cord-016871-1mlamf20	177	2	of	of	IN
cord-016871-1mlamf20	177	3	its	-PRON-	PRP$
cord-016871-1mlamf20	177	4	physiological	physiological	JJ
cord-016871-1mlamf20	177	5	ratios	ratio	NNS
cord-016871-1mlamf20	177	6	of	of	IN
cord-016871-1mlamf20	177	7	each	each	DT
cord-016871-1mlamf20	177	8	blood	blood	NN
cord-016871-1mlamf20	177	9	component	component	NN
cord-016871-1mlamf20	177	10	,	,	,
cord-016871-1mlamf20	177	11	it	-PRON-	PRP
cord-016871-1mlamf20	177	12	may	may	MD
cord-016871-1mlamf20	177	13	hold	hold	VB
cord-016871-1mlamf20	177	14	an	an	DT
cord-016871-1mlamf20	177	15	advantage	advantage	NN
cord-016871-1mlamf20	177	16	over	over	IN
cord-016871-1mlamf20	177	17	individual	individual	JJ
cord-016871-1mlamf20	177	18	blood	blood	NN
cord-016871-1mlamf20	177	19	component	component	NN
cord-016871-1mlamf20	177	20	transfusions	transfusion	NNS
cord-016871-1mlamf20	177	21	,	,	,
cord-016871-1mlamf20	177	22	but	but	CC
cord-016871-1mlamf20	177	23	more	more	JJR
cord-016871-1mlamf20	177	24	work	work	NN
cord-016871-1mlamf20	177	25	is	be	VBZ
cord-016871-1mlamf20	177	26	necessary	necessary	JJ
cord-016871-1mlamf20	177	27	to	to	TO
cord-016871-1mlamf20	177	28	substantiate	substantiate	VB
cord-016871-1mlamf20	177	29	this	this	DT
cord-016871-1mlamf20	177	30	idea	idea	NN
cord-016871-1mlamf20	177	31	.	.	.
cord-016871-1mlamf20	178	1	Recombinant	recombinant	JJ
cord-016871-1mlamf20	178	2	activated	activate	VBN
cord-016871-1mlamf20	178	3	factor	factor	NN
cord-016871-1mlamf20	178	4	VII	VII	NNP
cord-016871-1mlamf20	178	5	(	(	-LRB-
cord-016871-1mlamf20	178	6	rFVIIa	rfviia	NN
cord-016871-1mlamf20	178	7	)	)	-RRB-
cord-016871-1mlamf20	178	8	,	,	,
cord-016871-1mlamf20	178	9	originally	originally	RB
cord-016871-1mlamf20	178	10	developed	develop	VBN
cord-016871-1mlamf20	178	11	for	for	IN
cord-016871-1mlamf20	178	12	use	use	NN
cord-016871-1mlamf20	178	13	in	in	IN
cord-016871-1mlamf20	178	14	hemophilia	hemophilia	NN
cord-016871-1mlamf20	178	15	A	a	NN
cord-016871-1mlamf20	178	16	and	and	CC
cord-016871-1mlamf20	178	17	B	b	NN
cord-016871-1mlamf20	178	18	patients	patient	NNS
cord-016871-1mlamf20	178	19	,	,	,
cord-016871-1mlamf20	178	20	has	have	VBZ
cord-016871-1mlamf20	178	21	recently	recently	RB
cord-016871-1mlamf20	178	22	been	be	VBN
cord-016871-1mlamf20	178	23	explored	explore	VBN
cord-016871-1mlamf20	178	24	in	in	IN
cord-016871-1mlamf20	178	25	various	various	JJ
cord-016871-1mlamf20	178	26	off	off	JJ
cord-016871-1mlamf20	178	27	-	-	HYPH
cord-016871-1mlamf20	178	28	label	label	NN
cord-016871-1mlamf20	178	29	uses	use	NNS
cord-016871-1mlamf20	178	30	,	,	,
cord-016871-1mlamf20	178	31	such	such	JJ
cord-016871-1mlamf20	178	32	as	as	IN
cord-016871-1mlamf20	178	33	stemming	stem	VBG
cord-016871-1mlamf20	178	34	acute	acute	JJ
cord-016871-1mlamf20	178	35	bleeding	bleed	VBG
cord-016871-1mlamf20	178	36	alongside	alongside	IN
cord-016871-1mlamf20	178	37	standard	standard	JJ
cord-016871-1mlamf20	178	38	replacement	replacement	NN
cord-016871-1mlamf20	178	39	therapy	therapy	NN
cord-016871-1mlamf20	178	40	.	.	.
cord-016871-1mlamf20	179	1	Mayo	Mayo	NNP
cord-016871-1mlamf20	179	2	et	et	NNP
cord-016871-1mlamf20	179	3	al	al	NNP
cord-016871-1mlamf20	179	4	.	.	.
cord-016871-1mlamf20	180	1	demonstrate	demonstrate	VB
cord-016871-1mlamf20	180	2	the	the	DT
cord-016871-1mlamf20	180	3	use	use	NN
cord-016871-1mlamf20	180	4	of	of	IN
cord-016871-1mlamf20	180	5	a	a	DT
cord-016871-1mlamf20	180	6	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	180	7	score	score	NN
cord-016871-1mlamf20	180	8	that	that	WDT
cord-016871-1mlamf20	180	9	they	-PRON-	PRP
cord-016871-1mlamf20	180	10	found	find	VBD
cord-016871-1mlamf20	180	11	to	to	TO
cord-016871-1mlamf20	180	12	be	be	VB
cord-016871-1mlamf20	180	13	statistically	statistically	RB
cord-016871-1mlamf20	180	14	correlated	correlate	VBN
cord-016871-1mlamf20	180	15	to	to	TO
cord-016871-1mlamf20	180	16	rFVIIa	rfviia	NN
cord-016871-1mlamf20	180	17	response	response	NN
cord-016871-1mlamf20	180	18	and	and	CC
cord-016871-1mlamf20	180	19	survival	survival	NN
cord-016871-1mlamf20	180	20	in	in	IN
cord-016871-1mlamf20	180	21	13	13	CD
cord-016871-1mlamf20	180	22	trauma	trauma	NN
cord-016871-1mlamf20	180	23	patients	patient	NNS
cord-016871-1mlamf20	180	24	in	in	IN
cord-016871-1mlamf20	180	25	Israel	Israel	NNP
cord-016871-1mlamf20	180	26	[	[	-LRB-
cord-016871-1mlamf20	180	27	41	41	CD
cord-016871-1mlamf20	180	28	]	]	-RRB-
cord-016871-1mlamf20	180	29	.	.	.
cord-016871-1mlamf20	181	1	This	this	DT
cord-016871-1mlamf20	181	2	fi	fi	NN
cord-016871-1mlamf20	181	3	nding	nding	NN
cord-016871-1mlamf20	181	4	was	be	VBD
cord-016871-1mlamf20	181	5	a	a	DT
cord-016871-1mlamf20	181	6	turning	turning	NN
cord-016871-1mlamf20	181	7	point	point	NN
cord-016871-1mlamf20	181	8	in	in	IN
cord-016871-1mlamf20	181	9	the	the	DT
cord-016871-1mlamf20	181	10	understanding	understanding	NN
cord-016871-1mlamf20	181	11	of	of	IN
cord-016871-1mlamf20	181	12	rFVIIa	rfviia	NN
cord-016871-1mlamf20	181	13	indications	indication	NNS
cord-016871-1mlamf20	181	14	due	due	JJ
cord-016871-1mlamf20	181	15	to	to	IN
cord-016871-1mlamf20	181	16	its	-PRON-	PRP$
cord-016871-1mlamf20	181	17	previous	previous	JJ
cord-016871-1mlamf20	181	18	contraindication	contraindication	NN
cord-016871-1mlamf20	181	19	in	in	IN
cord-016871-1mlamf20	181	20	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	181	21	.	.	.
cord-016871-1mlamf20	182	1	Other	other	JJ
cord-016871-1mlamf20	182	2	uses	use	NNS
cord-016871-1mlamf20	182	3	for	for	IN
cord-016871-1mlamf20	182	4	rFVIIa	rfviia	NN
cord-016871-1mlamf20	182	5	are	be	VBP
cord-016871-1mlamf20	182	6	factor	factor	NN
cord-016871-1mlamf20	182	7	VII	VII	NNP
cord-016871-1mlamf20	182	8	de	de	NNP
cord-016871-1mlamf20	182	9	fi	fi	NNP
cord-016871-1mlamf20	182	10	ciency	ciency	NN
cord-016871-1mlamf20	182	11	,	,	,
cord-016871-1mlamf20	182	12	thrombocytopenia	thrombocytopenia	NN
cord-016871-1mlamf20	182	13	,	,	,
cord-016871-1mlamf20	182	14	functional	functional	JJ
cord-016871-1mlamf20	182	15	platelet	platelet	NN
cord-016871-1mlamf20	182	16	disorders	disorder	NNS
cord-016871-1mlamf20	182	17	,	,	,
cord-016871-1mlamf20	182	18	von	von	NNP
cord-016871-1mlamf20	182	19	Willebrand	Willebrand	NNP
cord-016871-1mlamf20	182	20	disease	disease	NN
cord-016871-1mlamf20	182	21	,	,	,
cord-016871-1mlamf20	182	22	intracranial	intracranial	JJ
cord-016871-1mlamf20	182	23	bleeding	bleeding	NN
cord-016871-1mlamf20	182	24	,	,	,
cord-016871-1mlamf20	182	25	and	and	CC
cord-016871-1mlamf20	182	26	reversal	reversal	NN
cord-016871-1mlamf20	182	27	of	of	IN
cord-016871-1mlamf20	182	28	warfarin	warfarin	JJ
cord-016871-1mlamf20	182	29	overdose	overdose	NN
cord-016871-1mlamf20	182	30	,	,	,
cord-016871-1mlamf20	182	31	liver	liver	NN
cord-016871-1mlamf20	182	32	disease	disease	NN
cord-016871-1mlamf20	182	33	,	,	,
cord-016871-1mlamf20	182	34	and	and	CC
cord-016871-1mlamf20	182	35	transplantation	transplantation	NN
cord-016871-1mlamf20	182	36	.	.	.
cord-016871-1mlamf20	183	1	However	however	RB
cord-016871-1mlamf20	183	2	,	,	,
cord-016871-1mlamf20	183	3	little	little	JJ
cord-016871-1mlamf20	183	4	evidence	evidence	NN
cord-016871-1mlamf20	183	5	is	be	VBZ
cord-016871-1mlamf20	183	6	currently	currently	RB
cord-016871-1mlamf20	183	7	available	available	JJ
cord-016871-1mlamf20	183	8	to	to	TO
cord-016871-1mlamf20	183	9	support	support	VB
cord-016871-1mlamf20	183	10	these	these	DT
cord-016871-1mlamf20	183	11	uses	use	NNS
cord-016871-1mlamf20	183	12	[	[	-LRB-
cord-016871-1mlamf20	183	13	41	41	CD
cord-016871-1mlamf20	183	14	]	]	-RRB-
cord-016871-1mlamf20	183	15	.	.	.
cord-016871-1mlamf20	184	1	Before	before	IN
cord-016871-1mlamf20	184	2	entering	enter	VBG
cord-016871-1mlamf20	184	3	the	the	DT
cord-016871-1mlamf20	184	4	discussion	discussion	NN
cord-016871-1mlamf20	184	5	on	on	IN
cord-016871-1mlamf20	184	6	complications	complication	NNS
cord-016871-1mlamf20	184	7	related	relate	VBN
cord-016871-1mlamf20	184	8	to	to	IN
cord-016871-1mlamf20	184	9	transfusions	transfusion	NNS
cord-016871-1mlamf20	184	10	,	,	,
cord-016871-1mlamf20	184	11	the	the	DT
cord-016871-1mlamf20	184	12	dif	dif	NNP
cord-016871-1mlamf20	184	13	fi	fi	NNP
cord-016871-1mlamf20	184	14	culty	culty	FW
cord-016871-1mlamf20	184	15	of	of	IN
cord-016871-1mlamf20	184	16	study	study	NN
cord-016871-1mlamf20	184	17	design	design	NN
cord-016871-1mlamf20	184	18	to	to	TO
cord-016871-1mlamf20	184	19	answer	answer	VB
cord-016871-1mlamf20	184	20	such	such	JJ
cord-016871-1mlamf20	184	21	questions	question	NNS
cord-016871-1mlamf20	184	22	must	must	MD
cord-016871-1mlamf20	184	23	be	be	VB
cord-016871-1mlamf20	184	24	appreciated	appreciate	VBN
cord-016871-1mlamf20	184	25	.	.	.
cord-016871-1mlamf20	185	1	There	there	EX
cord-016871-1mlamf20	185	2	are	be	VBP
cord-016871-1mlamf20	185	3	ethical	ethical	JJ
cord-016871-1mlamf20	185	4	obstacles	obstacle	NNS
cord-016871-1mlamf20	185	5	to	to	IN
cord-016871-1mlamf20	185	6	randomizing	randomize	VBG
cord-016871-1mlamf20	185	7	patients	patient	NNS
cord-016871-1mlamf20	185	8	to	to	IN
cord-016871-1mlamf20	185	9	transfusion	transfusion	NN
cord-016871-1mlamf20	185	10	and	and	CC
cord-016871-1mlamf20	185	11	non	non	JJ
cord-016871-1mlamf20	185	12	-	-	JJ
cord-016871-1mlamf20	185	13	transfusion	transfusion	JJ
cord-016871-1mlamf20	185	14	arms	arm	NNS
cord-016871-1mlamf20	185	15	.	.	.
cord-016871-1mlamf20	186	1	Hence	hence	RB
cord-016871-1mlamf20	186	2	,	,	,
cord-016871-1mlamf20	186	3	many	many	JJ
cord-016871-1mlamf20	186	4	trials	trial	NNS
cord-016871-1mlamf20	186	5	show	show	VBP
cord-016871-1mlamf20	186	6	patients	patient	NNS
cord-016871-1mlamf20	186	7	who	who	WP
cord-016871-1mlamf20	186	8	received	receive	VBD
cord-016871-1mlamf20	186	9	more	more	JJR
cord-016871-1mlamf20	186	10	blood	blood	NN
cord-016871-1mlamf20	186	11	component	component	NN
cord-016871-1mlamf20	186	12	transfusions	transfusion	NNS
cord-016871-1mlamf20	186	13	fared	fare	VBD
cord-016871-1mlamf20	186	14	worse	worse	RBR
cord-016871-1mlamf20	186	15	than	than	IN
cord-016871-1mlamf20	186	16	patients	patient	NNS
cord-016871-1mlamf20	186	17	who	who	WP
cord-016871-1mlamf20	186	18	did	do	VBD
cord-016871-1mlamf20	186	19	not	not	RB
cord-016871-1mlamf20	186	20	,	,	,
cord-016871-1mlamf20	186	21	but	but	CC
cord-016871-1mlamf20	186	22	this	this	DT
cord-016871-1mlamf20	186	23	may	may	MD
cord-016871-1mlamf20	186	24	be	be	VB
cord-016871-1mlamf20	186	25	entirely	entirely	RB
cord-016871-1mlamf20	186	26	because	because	IN
cord-016871-1mlamf20	186	27	of	of	IN
cord-016871-1mlamf20	186	28	the	the	DT
cord-016871-1mlamf20	186	29	condition	condition	NN
cord-016871-1mlamf20	186	30	of	of	IN
cord-016871-1mlamf20	186	31	the	the	DT
cord-016871-1mlamf20	186	32	patients	patient	NNS
cord-016871-1mlamf20	186	33	that	that	WDT
cord-016871-1mlamf20	186	34	necessitated	necessitate	VBD
cord-016871-1mlamf20	186	35	the	the	DT
cord-016871-1mlamf20	186	36	transfusions	transfusion	NNS
cord-016871-1mlamf20	186	37	[	[	-LRB-
cord-016871-1mlamf20	186	38	25	25	CD
cord-016871-1mlamf20	186	39	]	]	-RRB-
cord-016871-1mlamf20	186	40	.	.	.
cord-016871-1mlamf20	187	1	Khorana	Khorana	NNP
cord-016871-1mlamf20	187	2	et	et	FW
cord-016871-1mlamf20	187	3	al	al	NNP
cord-016871-1mlamf20	187	4	.	.	NNP
cord-016871-1mlamf20	187	5	's	's	POS
cord-016871-1mlamf20	187	6	retrospective	retrospective	JJ
cord-016871-1mlamf20	187	7	cohort	cohort	NN
cord-016871-1mlamf20	187	8	study	study	NN
cord-016871-1mlamf20	187	9	of	of	IN
cord-016871-1mlamf20	187	10	504,208	504,208	CD
cord-016871-1mlamf20	187	11	patients	patient	NNS
cord-016871-1mlamf20	187	12	hospitalized	hospitalize	VBN
cord-016871-1mlamf20	187	13	with	with	IN
cord-016871-1mlamf20	187	14	cancer	cancer	NN
cord-016871-1mlamf20	187	15	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	187	16	that	that	IN
cord-016871-1mlamf20	187	17	RBC	RBC	NNP
cord-016871-1mlamf20	187	18	and	and	CC
cord-016871-1mlamf20	187	19	platelet	platelet	NN
cord-016871-1mlamf20	187	20	transfusions	transfusion	NNS
cord-016871-1mlamf20	187	21	were	be	VBD
cord-016871-1mlamf20	187	22	associated	associate	VBN
cord-016871-1mlamf20	187	23	with	with	IN
cord-016871-1mlamf20	187	24	increased	increase	VBN
cord-016871-1mlamf20	187	25	mortality	mortality	NN
cord-016871-1mlamf20	187	26	,	,	,
cord-016871-1mlamf20	187	27	as	as	RB
cord-016871-1mlamf20	187	28	well	well	RB
cord-016871-1mlamf20	187	29	as	as	IN
cord-016871-1mlamf20	187	30	venous	venous	JJ
cord-016871-1mlamf20	187	31	and	and	CC
cord-016871-1mlamf20	187	32	arterial	arterial	JJ
cord-016871-1mlamf20	187	33	thrombotic	thrombotic	JJ
cord-016871-1mlamf20	187	34	events	event	NNS
cord-016871-1mlamf20	187	35	[	[	-LRB-
cord-016871-1mlamf20	187	36	42	42	CD
cord-016871-1mlamf20	187	37	]	]	-RRB-
cord-016871-1mlamf20	187	38	.	.	.
cord-016871-1mlamf20	188	1	However	however	RB
cord-016871-1mlamf20	188	2	,	,	,
cord-016871-1mlamf20	188	3	it	-PRON-	PRP
cord-016871-1mlamf20	188	4	is	be	VBZ
cord-016871-1mlamf20	188	5	unclear	unclear	JJ
cord-016871-1mlamf20	188	6	if	if	IN
cord-016871-1mlamf20	188	7	this	this	DT
cord-016871-1mlamf20	188	8	is	be	VBZ
cord-016871-1mlamf20	188	9	a	a	DT
cord-016871-1mlamf20	188	10	causal	causal	JJ
cord-016871-1mlamf20	188	11	relationship	relationship	NN
cord-016871-1mlamf20	188	12	.	.	.
cord-016871-1mlamf20	189	1	As	as	IN
cord-016871-1mlamf20	189	2	with	with	IN
cord-016871-1mlamf20	189	3	large	large	JJ
cord-016871-1mlamf20	189	4	-	-	HYPH
cord-016871-1mlamf20	189	5	scale	scale	NN
cord-016871-1mlamf20	189	6	introduction	introduction	NN
cord-016871-1mlamf20	189	7	of	of	IN
cord-016871-1mlamf20	189	8	exogenous	exogenous	JJ
cord-016871-1mlamf20	189	9	elements	element	NNS
cord-016871-1mlamf20	189	10	to	to	IN
cord-016871-1mlamf20	189	11	the	the	DT
cord-016871-1mlamf20	189	12	body	body	NN
cord-016871-1mlamf20	189	13	,	,	,
cord-016871-1mlamf20	189	14	immune	immune	JJ
cord-016871-1mlamf20	189	15	reactions	reaction	NNS
cord-016871-1mlamf20	189	16	can	can	MD
cord-016871-1mlamf20	189	17	develop	develop	VB
cord-016871-1mlamf20	189	18	,	,	,
cord-016871-1mlamf20	189	19	a	a	DT
cord-016871-1mlamf20	189	20	sequela	sequela	NN
cord-016871-1mlamf20	189	21	that	that	WDT
cord-016871-1mlamf20	189	22	is	be	VBZ
cord-016871-1mlamf20	189	23	notorious	notorious	JJ
cord-016871-1mlamf20	189	24	in	in	IN
cord-016871-1mlamf20	189	25	blood	blood	NN
cord-016871-1mlamf20	189	26	products	product	NNS
cord-016871-1mlamf20	189	27	.	.	.
cord-016871-1mlamf20	190	1	This	this	DT
cord-016871-1mlamf20	190	2	complication	complication	NN
cord-016871-1mlamf20	190	3	is	be	VBZ
cord-016871-1mlamf20	190	4	particularly	particularly	RB
cord-016871-1mlamf20	190	5	devastating	devastating	JJ
cord-016871-1mlamf20	190	6	in	in	IN
cord-016871-1mlamf20	190	7	severely	severely	RB
cord-016871-1mlamf20	190	8	ill	ill	JJ
cord-016871-1mlamf20	190	9	patients	patient	NNS
cord-016871-1mlamf20	190	10	.	.	.
cord-016871-1mlamf20	191	1	The	the	DT
cord-016871-1mlamf20	191	2	most	most	RBS
cord-016871-1mlamf20	191	3	notorious	notorious	JJ
cord-016871-1mlamf20	191	4	of	of	IN
cord-016871-1mlamf20	191	5	these	these	DT
cord-016871-1mlamf20	191	6	immune	immune	JJ
cord-016871-1mlamf20	191	7	reactions	reaction	NNS
cord-016871-1mlamf20	191	8	are	be	VBP
cord-016871-1mlamf20	191	9	hemolytic	hemolytic	JJ
cord-016871-1mlamf20	191	10	reactions	reaction	NNS
cord-016871-1mlamf20	191	11	.	.	.
cord-016871-1mlamf20	192	1	In	in	IN
cord-016871-1mlamf20	192	2	order	order	NN
cord-016871-1mlamf20	192	3	to	to	TO
cord-016871-1mlamf20	192	4	prevent	prevent	VB
cord-016871-1mlamf20	192	5	this	this	DT
cord-016871-1mlamf20	192	6	event	event	NN
cord-016871-1mlamf20	192	7	,	,	,
cord-016871-1mlamf20	192	8	it	-PRON-	PRP
cord-016871-1mlamf20	192	9	is	be	VBZ
cord-016871-1mlamf20	192	10	important	important	JJ
cord-016871-1mlamf20	192	11	to	to	TO
cord-016871-1mlamf20	192	12	cross	cross	VB
cord-016871-1mlamf20	192	13	-	-	JJ
cord-016871-1mlamf20	192	14	match	match	VB
cord-016871-1mlamf20	192	15	patient	patient	NN
cord-016871-1mlamf20	192	16	and	and	CC
cord-016871-1mlamf20	192	17	donor	donor	NN
cord-016871-1mlamf20	192	18	blood	blood	NN
cord-016871-1mlamf20	192	19	whenever	whenever	WRB
cord-016871-1mlamf20	192	20	possible	possible	JJ
cord-016871-1mlamf20	192	21	.	.	.
cord-016871-1mlamf20	193	1	The	the	DT
cord-016871-1mlamf20	193	2	most	most	RBS
cord-016871-1mlamf20	193	3	common	common	JJ
cord-016871-1mlamf20	193	4	cause	cause	NN
cord-016871-1mlamf20	193	5	of	of	IN
cord-016871-1mlamf20	193	6	hemolytic	hemolytic	JJ
cord-016871-1mlamf20	193	7	reactions	reaction	NNS
cord-016871-1mlamf20	193	8	due	due	JJ
cord-016871-1mlamf20	193	9	to	to	IN
cord-016871-1mlamf20	193	10	transfusion	transfusion	NN
cord-016871-1mlamf20	193	11	of	of	IN
cord-016871-1mlamf20	193	12	an	an	DT
cord-016871-1mlamf20	193	13	incorrect	incorrect	JJ
cord-016871-1mlamf20	193	14	match	match	NN
cord-016871-1mlamf20	193	15	is	be	VBZ
cord-016871-1mlamf20	193	16	clerical	clerical	JJ
cord-016871-1mlamf20	193	17	error	error	NN
cord-016871-1mlamf20	193	18	.	.	.
cord-016871-1mlamf20	194	1	Hemolytic	hemolytic	JJ
cord-016871-1mlamf20	194	2	reactions	reaction	NNS
cord-016871-1mlamf20	194	3	in	in	IN
cord-016871-1mlamf20	194	4	blood	blood	NN
cord-016871-1mlamf20	194	5	transfusions	transfusion	NNS
cord-016871-1mlamf20	194	6	occur	occur	VBP
cord-016871-1mlamf20	194	7	because	because	IN
cord-016871-1mlamf20	194	8	each	each	DT
cord-016871-1mlamf20	194	9	individual	individual	NN
cord-016871-1mlamf20	194	10	carries	carry	VBZ
cord-016871-1mlamf20	194	11	antibodies	antibody	NNS
cord-016871-1mlamf20	194	12	against	against	IN
cord-016871-1mlamf20	194	13	the	the	DT
cord-016871-1mlamf20	194	14	blood	blood	NN
cord-016871-1mlamf20	194	15	group	group	NN
cord-016871-1mlamf20	194	16	(	(	-LRB-
cord-016871-1mlamf20	194	17	A	a	NN
cord-016871-1mlamf20	194	18	or	or	CC
cord-016871-1mlamf20	194	19	B	b	NN
cord-016871-1mlamf20	194	20	)	)	-RRB-
cord-016871-1mlamf20	194	21	that	that	IN
cord-016871-1mlamf20	194	22	it	-PRON-	PRP
cord-016871-1mlamf20	194	23	does	do	VBZ
cord-016871-1mlamf20	194	24	not	not	RB
cord-016871-1mlamf20	194	25	express	express	VB
cord-016871-1mlamf20	194	26	endogenously	endogenously	RB
cord-016871-1mlamf20	194	27	.	.	.
cord-016871-1mlamf20	195	1	Hence	hence	RB
cord-016871-1mlamf20	195	2	,	,	,
cord-016871-1mlamf20	195	3	when	when	WRB
cord-016871-1mlamf20	195	4	products	product	NNS
cord-016871-1mlamf20	195	5	containing	contain	VBG
cord-016871-1mlamf20	195	6	anti	anti	JJ
cord-016871-1mlamf20	195	7	-	-	JJ
cord-016871-1mlamf20	195	8	A	a	JJ
cord-016871-1mlamf20	195	9	or	or	CC
cord-016871-1mlamf20	195	10	anti	anti	JJ
cord-016871-1mlamf20	195	11	-	-	JJ
cord-016871-1mlamf20	195	12	B	b	JJ
cord-016871-1mlamf20	195	13	antibodies	antibody	NNS
cord-016871-1mlamf20	195	14	in	in	IN
cord-016871-1mlamf20	195	15	plasma	plasma	NN
cord-016871-1mlamf20	195	16	,	,	,
cord-016871-1mlamf20	195	17	such	such	JJ
cord-016871-1mlamf20	195	18	as	as	IN
cord-016871-1mlamf20	195	19	plasma	plasma	NN
cord-016871-1mlamf20	195	20	,	,	,
cord-016871-1mlamf20	195	21	are	be	VBP
cord-016871-1mlamf20	195	22	transfused	transfuse	VBN
cord-016871-1mlamf20	195	23	to	to	IN
cord-016871-1mlamf20	195	24	patients	patient	NNS
cord-016871-1mlamf20	195	25	of	of	IN
cord-016871-1mlamf20	195	26	A	a	NN
cord-016871-1mlamf20	195	27	,	,	,
cord-016871-1mlamf20	195	28	B	b	NN
cord-016871-1mlamf20	195	29	,	,	,
cord-016871-1mlamf20	195	30	or	or	CC
cord-016871-1mlamf20	195	31	both	both	DT
cord-016871-1mlamf20	195	32	blood	blood	NN
cord-016871-1mlamf20	195	33	groups	group	NNS
cord-016871-1mlamf20	195	34	,	,	,
cord-016871-1mlamf20	195	35	the	the	DT
cord-016871-1mlamf20	195	36	donor	donor	NN
cord-016871-1mlamf20	195	37	antibodies	antibody	NNS
cord-016871-1mlamf20	195	38	stage	stage	VBP
cord-016871-1mlamf20	195	39	an	an	DT
cord-016871-1mlamf20	195	40	attack	attack	NN
cord-016871-1mlamf20	195	41	on	on	IN
cord-016871-1mlamf20	195	42	the	the	DT
cord-016871-1mlamf20	195	43	patient	patient	NN
cord-016871-1mlamf20	195	44	's	's	POS
cord-016871-1mlamf20	195	45	red	red	JJ
cord-016871-1mlamf20	195	46	blood	blood	NN
cord-016871-1mlamf20	195	47	cells	cell	NNS
cord-016871-1mlamf20	195	48	.	.	.
cord-016871-1mlamf20	196	1	Allergic	allergic	JJ
cord-016871-1mlamf20	196	2	reactions	reaction	NNS
cord-016871-1mlamf20	196	3	are	be	VBP
cord-016871-1mlamf20	196	4	another	another	DT
cord-016871-1mlamf20	196	5	common	common	JJ
cord-016871-1mlamf20	196	6	immune	immune	NN
cord-016871-1mlamf20	196	7	-	-	HYPH
cord-016871-1mlamf20	196	8	mediated	mediate	VBN
cord-016871-1mlamf20	196	9	complication	complication	NN
cord-016871-1mlamf20	196	10	of	of	IN
cord-016871-1mlamf20	196	11	transfusions	transfusion	NNS
cord-016871-1mlamf20	196	12	.	.	.
cord-016871-1mlamf20	197	1	Severely	severely	RB
cord-016871-1mlamf20	197	2	anaphylactic	anaphylactic	JJ
cord-016871-1mlamf20	197	3	reactions	reaction	NNS
cord-016871-1mlamf20	197	4	are	be	VBP
cord-016871-1mlamf20	197	5	more	more	RBR
cord-016871-1mlamf20	197	6	common	common	JJ
cord-016871-1mlamf20	197	7	after	after	IN
cord-016871-1mlamf20	197	8	plasma	plasma	NN
cord-016871-1mlamf20	197	9	compared	compare	VBN
cord-016871-1mlamf20	197	10	to	to	IN
cord-016871-1mlamf20	197	11	RBC	RBC	NNP
cord-016871-1mlamf20	197	12	transfusion	transfusion	NN
cord-016871-1mlamf20	197	13	[	[	-LRB-
cord-016871-1mlamf20	197	14	35	35	CD
cord-016871-1mlamf20	197	15	]	]	-RRB-
cord-016871-1mlamf20	197	16	.	.	.
cord-016871-1mlamf20	198	1	Patients	patient	NNS
cord-016871-1mlamf20	198	2	present	present	JJ
cord-016871-1mlamf20	198	3	with	with	IN
cord-016871-1mlamf20	198	4	wheeze	wheeze	NN
cord-016871-1mlamf20	198	5	,	,	,
cord-016871-1mlamf20	198	6	hypotension	hypotension	NN
cord-016871-1mlamf20	198	7	,	,	,
cord-016871-1mlamf20	198	8	tachycardia	tachycardia	NN
cord-016871-1mlamf20	198	9	,	,	,
cord-016871-1mlamf20	198	10	laryngeal	laryngeal	NN
cord-016871-1mlamf20	198	11	edema	edema	NN
cord-016871-1mlamf20	198	12	,	,	,
cord-016871-1mlamf20	198	13	and	and	CC
cord-016871-1mlamf20	198	14	urticarial	urticarial	JJ
cord-016871-1mlamf20	198	15	rash	rash	NN
cord-016871-1mlamf20	198	16	.	.	.
cord-016871-1mlamf20	199	1	TRALI	TRALI	NNP
cord-016871-1mlamf20	199	2	is	be	VBZ
cord-016871-1mlamf20	199	3	de	de	FW
cord-016871-1mlamf20	199	4	fi	fi	NNP
cord-016871-1mlamf20	199	5	ned	ned	NNP
cord-016871-1mlamf20	199	6	as	as	IN
cord-016871-1mlamf20	199	7	acute	acute	JJ
cord-016871-1mlamf20	199	8	lung	lung	NN
cord-016871-1mlamf20	199	9	injury	injury	NN
cord-016871-1mlamf20	199	10	occurring	occur	VBG
cord-016871-1mlamf20	199	11	within	within	IN
cord-016871-1mlamf20	199	12	6	6	CD
cord-016871-1mlamf20	199	13	h	h	NN
cord-016871-1mlamf20	199	14	of	of	IN
cord-016871-1mlamf20	199	15	transfusion	transfusion	NN
cord-016871-1mlamf20	199	16	with	with	IN
cord-016871-1mlamf20	199	17	a	a	DT
cord-016871-1mlamf20	199	18	blood	blood	NN
cord-016871-1mlamf20	199	19	product	product	NN
cord-016871-1mlamf20	199	20	,	,	,
cord-016871-1mlamf20	199	21	with	with	IN
cord-016871-1mlamf20	199	22	most	most	JJS
cord-016871-1mlamf20	199	23	commonly	commonly	RB
cord-016871-1mlamf20	199	24	reported	report	VBN
cord-016871-1mlamf20	199	25	cases	case	NNS
cord-016871-1mlamf20	199	26	occurring	occur	VBG
cord-016871-1mlamf20	199	27	due	due	IN
cord-016871-1mlamf20	199	28	to	to	IN
cord-016871-1mlamf20	199	29	FFP	FFP	NNP
cord-016871-1mlamf20	199	30	[	[	-LRB-
cord-016871-1mlamf20	199	31	43	43	CD
cord-016871-1mlamf20	199	32	]	]	-RRB-
cord-016871-1mlamf20	199	33	.	.	.
cord-016871-1mlamf20	200	1	TRALI	TRALI	NNP
cord-016871-1mlamf20	200	2	is	be	VBZ
cord-016871-1mlamf20	200	3	the	the	DT
cord-016871-1mlamf20	200	4	most	most	RBS
cord-016871-1mlamf20	200	5	common	common	JJ
cord-016871-1mlamf20	200	6	cause	cause	NN
cord-016871-1mlamf20	200	7	of	of	IN
cord-016871-1mlamf20	200	8	death	death	NN
cord-016871-1mlamf20	200	9	due	due	IN
cord-016871-1mlamf20	200	10	to	to	IN
cord-016871-1mlamf20	200	11	transfusion	transfusion	NN
cord-016871-1mlamf20	200	12	[	[	-LRB-
cord-016871-1mlamf20	200	13	35	35	CD
cord-016871-1mlamf20	200	14	]	]	-RRB-
cord-016871-1mlamf20	200	15	.	.	.
cord-016871-1mlamf20	201	1	TRALI	TRALI	NNP
cord-016871-1mlamf20	201	2	is	be	VBZ
cord-016871-1mlamf20	201	3	characterized	characterize	VBN
cord-016871-1mlamf20	201	4	by	by	IN
cord-016871-1mlamf20	201	5	respiratory	respiratory	JJ
cord-016871-1mlamf20	201	6	insuf	insuf	NN
cord-016871-1mlamf20	201	7	fi	fi	NN
cord-016871-1mlamf20	201	8	ciency	ciency	NNP
cord-016871-1mlamf20	201	9	,	,	,
cord-016871-1mlamf20	201	10	not	not	RB
cord-016871-1mlamf20	201	11	limited	limit	VBN
cord-016871-1mlamf20	201	12	to	to	IN
cord-016871-1mlamf20	201	13	but	but	CC
cord-016871-1mlamf20	201	14	including	include	VBG
cord-016871-1mlamf20	201	15	tachypnea	tachypnea	NNP
cord-016871-1mlamf20	201	16	,	,	,
cord-016871-1mlamf20	201	17	cyanosis	cyanosis	NN
cord-016871-1mlamf20	201	18	,	,	,
cord-016871-1mlamf20	201	19	dyspnea	dyspnea	NN
cord-016871-1mlamf20	201	20	,	,	,
cord-016871-1mlamf20	201	21	and	and	CC
cord-016871-1mlamf20	201	22	acute	acute	JJ
cord-016871-1mlamf20	201	23	hypoxemia	hypoxemia	NN
cord-016871-1mlamf20	201	24	[	[	-LRB-
cord-016871-1mlamf20	201	25	43	43	CD
cord-016871-1mlamf20	201	26	]	]	-RRB-
cord-016871-1mlamf20	201	27	.	.	.
cord-016871-1mlamf20	202	1	Unfortunately	unfortunately	RB
cord-016871-1mlamf20	202	2	,	,	,
cord-016871-1mlamf20	202	3	the	the	DT
cord-016871-1mlamf20	202	4	occurrence	occurrence	NN
cord-016871-1mlamf20	202	5	of	of	IN
cord-016871-1mlamf20	202	6	TRALI	TRALI	NNP
cord-016871-1mlamf20	202	7	in	in	IN
cord-016871-1mlamf20	202	8	critically	critically	RB
cord-016871-1mlamf20	202	9	ill	ill	JJ
cord-016871-1mlamf20	202	10	patients	patient	NNS
cord-016871-1mlamf20	202	11	who	who	WP
cord-016871-1mlamf20	202	12	received	receive	VBD
cord-016871-1mlamf20	202	13	a	a	DT
cord-016871-1mlamf20	202	14	blood	blood	NN
cord-016871-1mlamf20	202	15	transfusion	transfusion	NN
cord-016871-1mlamf20	202	16	is	be	VBZ
cord-016871-1mlamf20	202	17	estimated	estimate	VBN
cord-016871-1mlamf20	202	18	to	to	TO
cord-016871-1mlamf20	202	19	be	be	VB
cord-016871-1mlamf20	202	20	around	around	RB
cord-016871-1mlamf20	202	21	25	25	CD
cord-016871-1mlamf20	202	22	%	%	NN
cord-016871-1mlamf20	202	23	and	and	CC
cord-016871-1mlamf20	202	24	increases	increase	NNS
cord-016871-1mlamf20	202	25	with	with	IN
cord-016871-1mlamf20	202	26	each	each	DT
cord-016871-1mlamf20	202	27	subsequent	subsequent	JJ
cord-016871-1mlamf20	202	28	transfusion	transfusion	NN
cord-016871-1mlamf20	202	29	,	,	,
cord-016871-1mlamf20	202	30	has	have	VBZ
cord-016871-1mlamf20	202	31	a	a	DT
cord-016871-1mlamf20	202	32	mortality	mortality	NN
cord-016871-1mlamf20	202	33	rate	rate	NN
cord-016871-1mlamf20	202	34	of	of	IN
cord-016871-1mlamf20	202	35	approximately	approximately	RB
cord-016871-1mlamf20	202	36	40	40	CD
cord-016871-1mlamf20	202	37	%	%	NN
cord-016871-1mlamf20	202	38	,	,	,
cord-016871-1mlamf20	202	39	and	and	CC
cord-016871-1mlamf20	202	40	it	-PRON-	PRP
cord-016871-1mlamf20	202	41	is	be	VBZ
cord-016871-1mlamf20	202	42	the	the	DT
cord-016871-1mlamf20	202	43	most	most	RBS
cord-016871-1mlamf20	202	44	common	common	JJ
cord-016871-1mlamf20	202	45	transfusion	transfusion	NN
cord-016871-1mlamf20	202	46	-	-	HYPH
cord-016871-1mlamf20	202	47	related	relate	VBN
cord-016871-1mlamf20	202	48	complication	complication	NN
cord-016871-1mlamf20	202	49	[	[	-LRB-
cord-016871-1mlamf20	202	50	16	16	CD
cord-016871-1mlamf20	202	51	]	]	-RRB-
cord-016871-1mlamf20	202	52	.	.	.
cord-016871-1mlamf20	203	1	Eighty	eighty	CD
cord-016871-1mlamf20	203	2	-	-	HYPH
cord-016871-1mlamf20	203	3	fi	fi	NNP
cord-016871-1mlamf20	203	4	ve	ve	VBD
cord-016871-1mlamf20	203	5	percent	percent	NN
cord-016871-1mlamf20	203	6	of	of	IN
cord-016871-1mlamf20	203	7	patients	patient	NNS
cord-016871-1mlamf20	203	8	with	with	IN
cord-016871-1mlamf20	203	9	bleeding	bleed	VBG
cord-016871-1mlamf20	203	10	varices	varix	NNS
cord-016871-1mlamf20	203	11	receive	receive	VBP
cord-016871-1mlamf20	203	12	blood	blood	NN
cord-016871-1mlamf20	203	13	transfusions	transfusion	NNS
cord-016871-1mlamf20	203	14	,	,	,
cord-016871-1mlamf20	203	15	and	and	CC
cord-016871-1mlamf20	203	16	the	the	DT
cord-016871-1mlamf20	203	17	trigger	trigger	NN
cord-016871-1mlamf20	203	18	for	for	IN
cord-016871-1mlamf20	203	19	transfusions	transfusion	NNS
cord-016871-1mlamf20	203	20	is	be	VBZ
cord-016871-1mlamf20	203	21	much	much	RB
cord-016871-1mlamf20	203	22	debated	debate	VBN
cord-016871-1mlamf20	203	23	.	.	.
cord-016871-1mlamf20	204	1	In	in	IN
cord-016871-1mlamf20	204	2	patients	patient	NNS
cord-016871-1mlamf20	204	3	with	with	IN
cord-016871-1mlamf20	204	4	gastrointestinal	gastrointestinal	JJ
cord-016871-1mlamf20	204	5	bleeding	bleeding	NN
cord-016871-1mlamf20	204	6	,	,	,
cord-016871-1mlamf20	204	7	TRALI	TRALI	NNP
cord-016871-1mlamf20	204	8	is	be	VBZ
cord-016871-1mlamf20	204	9	further	far	RBR
cord-016871-1mlamf20	204	10	exacerbated	exacerbate	VBN
cord-016871-1mlamf20	204	11	by	by	IN
cord-016871-1mlamf20	204	12	the	the	DT
cord-016871-1mlamf20	204	13	presence	presence	NN
cord-016871-1mlamf20	204	14	of	of	IN
cord-016871-1mlamf20	204	15	end	end	NN
cord-016871-1mlamf20	204	16	-	-	HYPH
cord-016871-1mlamf20	204	17	stage	stage	NN
cord-016871-1mlamf20	204	18	liver	liver	NN
cord-016871-1mlamf20	204	19	disease	disease	NN
cord-016871-1mlamf20	204	20	.	.	.
cord-016871-1mlamf20	205	1	Proposed	propose	VBN
cord-016871-1mlamf20	205	2	mechanisms	mechanism	NNS
cord-016871-1mlamf20	205	3	for	for	IN
cord-016871-1mlamf20	205	4	this	this	DT
cord-016871-1mlamf20	205	5	phenomenon	phenomenon	NN
cord-016871-1mlamf20	205	6	have	have	VBP
cord-016871-1mlamf20	205	7	included	include	VBN
cord-016871-1mlamf20	205	8	antibody	antibody	NN
cord-016871-1mlamf20	205	9	-	-	HYPH
cord-016871-1mlamf20	205	10	mediated	mediate	VBN
cord-016871-1mlamf20	205	11	reactions	reaction	NNS
cord-016871-1mlamf20	205	12	,	,	,
cord-016871-1mlamf20	205	13	but	but	CC
cord-016871-1mlamf20	205	14	these	these	DT
cord-016871-1mlamf20	205	15	fi	fi	NNP
cord-016871-1mlamf20	205	16	ndings	nding	NNS
cord-016871-1mlamf20	205	17	are	be	VBP
cord-016871-1mlamf20	205	18	not	not	RB
cord-016871-1mlamf20	205	19	de	de	FW
cord-016871-1mlamf20	205	20	fi	fi	NNP
cord-016871-1mlamf20	205	21	nitive	nitive	JJ
cord-016871-1mlamf20	205	22	and	and	CC
cord-016871-1mlamf20	205	23	many	many	JJ
cord-016871-1mlamf20	205	24	are	be	VBP
cord-016871-1mlamf20	205	25	subject	subject	JJ
cord-016871-1mlamf20	205	26	to	to	IN
cord-016871-1mlamf20	205	27	selection	selection	NN
cord-016871-1mlamf20	205	28	bias	bias	NN
cord-016871-1mlamf20	205	29	due	due	IN
cord-016871-1mlamf20	205	30	to	to	IN
cord-016871-1mlamf20	205	31	no	no	DT
cord-016871-1mlamf20	205	32	screening	screening	NN
cord-016871-1mlamf20	205	33	in	in	IN
cord-016871-1mlamf20	205	34	the	the	DT
cord-016871-1mlamf20	205	35	asymptomatic	asymptomatic	JJ
cord-016871-1mlamf20	205	36	population	population	NN
cord-016871-1mlamf20	205	37	[	[	-LRB-
cord-016871-1mlamf20	205	38	43	43	CD
cord-016871-1mlamf20	205	39	]	]	-RRB-
cord-016871-1mlamf20	205	40	.	.	.
cord-016871-1mlamf20	206	1	Autopsies	autopsy	NNS
cord-016871-1mlamf20	206	2	and	and	CC
cord-016871-1mlamf20	206	3	animal	animal	NN
cord-016871-1mlamf20	206	4	models	model	NNS
cord-016871-1mlamf20	206	5	have	have	VBP
cord-016871-1mlamf20	206	6	suggested	suggest	VBN
cord-016871-1mlamf20	206	7	hyperactive	hyperactive	JJ
cord-016871-1mlamf20	206	8	PMN	PMN	NNP
cord-016871-1mlamf20	206	9	involvement	involvement	NN
cord-016871-1mlamf20	206	10	,	,	,
cord-016871-1mlamf20	206	11	since	since	IN
cord-016871-1mlamf20	206	12	mass	mass	NN
cord-016871-1mlamf20	206	13	in	in	IN
cord-016871-1mlamf20	206	14	fi	fi	NNP
cord-016871-1mlamf20	206	15	ltration	ltration	NN
cord-016871-1mlamf20	206	16	was	be	VBD
cord-016871-1mlamf20	206	17	noted	note	VBN
cord-016871-1mlamf20	206	18	[	[	-LRB-
cord-016871-1mlamf20	206	19	43	43	CD
cord-016871-1mlamf20	206	20	]	]	-RRB-
cord-016871-1mlamf20	206	21	.	.	.
cord-016871-1mlamf20	207	1	A	a	DT
cord-016871-1mlamf20	207	2	two	two	CD
cord-016871-1mlamf20	207	3	-	-	HYPH
cord-016871-1mlamf20	207	4	event	event	NN
cord-016871-1mlamf20	207	5	model	model	NN
cord-016871-1mlamf20	207	6	has	have	VBZ
cord-016871-1mlamf20	207	7	also	also	RB
cord-016871-1mlamf20	207	8	been	be	VBN
cord-016871-1mlamf20	207	9	proposed	propose	VBN
cord-016871-1mlamf20	207	10	,	,	,
cord-016871-1mlamf20	207	11	with	with	IN
cord-016871-1mlamf20	207	12	the	the	DT
cord-016871-1mlamf20	207	13	fi	fi	NNP
cord-016871-1mlamf20	207	14	rst	rst	NN
cord-016871-1mlamf20	207	15	event	event	NN
cord-016871-1mlamf20	207	16	dictated	dictate	VBN
cord-016871-1mlamf20	207	17	by	by	IN
cord-016871-1mlamf20	207	18	the	the	DT
cord-016871-1mlamf20	207	19	clinical	clinical	JJ
cord-016871-1mlamf20	207	20	health	health	NN
cord-016871-1mlamf20	207	21	of	of	IN
cord-016871-1mlamf20	207	22	the	the	DT
cord-016871-1mlamf20	207	23	patient	patient	NN
cord-016871-1mlamf20	207	24	and	and	CC
cord-016871-1mlamf20	207	25	the	the	DT
cord-016871-1mlamf20	207	26	second	second	JJ
cord-016871-1mlamf20	207	27	event	event	NN
cord-016871-1mlamf20	207	28	by	by	IN
cord-016871-1mlamf20	207	29	the	the	DT
cord-016871-1mlamf20	207	30	quality	quality	NN
cord-016871-1mlamf20	207	31	(	(	-LRB-
cord-016871-1mlamf20	207	32	affected	affect	VBN
cord-016871-1mlamf20	207	33	by	by	IN
cord-016871-1mlamf20	207	34	storage	storage	NN
cord-016871-1mlamf20	207	35	,	,	,
cord-016871-1mlamf20	207	36	donor	donor	NN
cord-016871-1mlamf20	207	37	immunologic	immunologic	JJ
cord-016871-1mlamf20	207	38	components	component	NNS
cord-016871-1mlamf20	207	39	)	)	-RRB-
cord-016871-1mlamf20	207	40	of	of	IN
cord-016871-1mlamf20	207	41	the	the	DT
cord-016871-1mlamf20	207	42	blood	blood	NN
cord-016871-1mlamf20	207	43	product	product	NN
cord-016871-1mlamf20	207	44	[	[	-LRB-
cord-016871-1mlamf20	207	45	43	43	CD
cord-016871-1mlamf20	207	46	]	]	-RRB-
cord-016871-1mlamf20	207	47	.	.	.
cord-016871-1mlamf20	208	1	The	the	DT
cord-016871-1mlamf20	208	2	treatment	treatment	NN
cord-016871-1mlamf20	208	3	of	of	IN
cord-016871-1mlamf20	208	4	TRALI	TRALI	NNP
cord-016871-1mlamf20	208	5	is	be	VBZ
cord-016871-1mlamf20	208	6	aggressive	aggressive	JJ
cord-016871-1mlamf20	208	7	respiratory	respiratory	JJ
cord-016871-1mlamf20	208	8	support	support	NN
cord-016871-1mlamf20	208	9	and	and	CC
cord-016871-1mlamf20	208	10	ventilation	ventilation	NN
cord-016871-1mlamf20	208	11	in	in	IN
cord-016871-1mlamf20	208	12	more	more	JJR
cord-016871-1mlamf20	208	13	severe	severe	JJ
cord-016871-1mlamf20	208	14	cases	case	NNS
cord-016871-1mlamf20	208	15	,	,	,
cord-016871-1mlamf20	208	16	such	such	JJ
cord-016871-1mlamf20	208	17	as	as	IN
cord-016871-1mlamf20	208	18	in	in	IN
cord-016871-1mlamf20	208	19	critically	critically	RB
cord-016871-1mlamf20	208	20	ill	ill	JJ
cord-016871-1mlamf20	208	21	patients	patient	NNS
cord-016871-1mlamf20	208	22	[	[	-LRB-
cord-016871-1mlamf20	208	23	43	43	CD
cord-016871-1mlamf20	208	24	]	]	-RRB-
cord-016871-1mlamf20	208	25	.	.	.
cord-016871-1mlamf20	209	1	Practices	practice	NNS
cord-016871-1mlamf20	209	2	to	to	TO
cord-016871-1mlamf20	209	3	reduce	reduce	VB
cord-016871-1mlamf20	209	4	the	the	DT
cord-016871-1mlamf20	209	5	risk	risk	NN
cord-016871-1mlamf20	209	6	of	of	IN
cord-016871-1mlamf20	209	7	TRALI	TRALI	NNP
cord-016871-1mlamf20	209	8	include	include	VBP
cord-016871-1mlamf20	209	9	prestorage	prestorage	NN
cord-016871-1mlamf20	209	10	leukoreduction	leukoreduction	NN
cord-016871-1mlamf20	209	11	as	as	RB
cord-016871-1mlamf20	209	12	well	well	RB
cord-016871-1mlamf20	209	13	as	as	IN
cord-016871-1mlamf20	209	14	avoiding	avoid	VBG
cord-016871-1mlamf20	209	15	the	the	DT
cord-016871-1mlamf20	209	16	use	use	NN
cord-016871-1mlamf20	209	17	of	of	IN
cord-016871-1mlamf20	209	18	old	old	JJ
cord-016871-1mlamf20	209	19	blood	blood	NN
cord-016871-1mlamf20	209	20	products	product	NNS
cord-016871-1mlamf20	209	21	,	,	,
cord-016871-1mlamf20	209	22	de	de	FW
cord-016871-1mlamf20	209	23	fi	fi	NNP
cord-016871-1mlamf20	209	24	ned	ned	NNP
cord-016871-1mlamf20	209	25	as	as	IN
cord-016871-1mlamf20	209	26	older	old	JJR
cord-016871-1mlamf20	209	27	than	than	IN
cord-016871-1mlamf20	209	28	14	14	CD
cord-016871-1mlamf20	209	29	days	day	NNS
cord-016871-1mlamf20	209	30	for	for	IN
cord-016871-1mlamf20	209	31	RBCs	rbc	NNS
cord-016871-1mlamf20	209	32	and	and	CC
cord-016871-1mlamf20	209	33	older	old	JJR
cord-016871-1mlamf20	209	34	than	than	IN
cord-016871-1mlamf20	209	35	2	2	CD
cord-016871-1mlamf20	209	36	days	day	NNS
cord-016871-1mlamf20	209	37	for	for	IN
cord-016871-1mlamf20	209	38	platelet	platelet	NN
cord-016871-1mlamf20	209	39	concentrates	concentrate	NNS
cord-016871-1mlamf20	209	40	.	.	.
cord-016871-1mlamf20	210	1	Another	another	DT
cord-016871-1mlamf20	210	2	prevention	prevention	NN
cord-016871-1mlamf20	210	3	strategy	strategy	NN
cord-016871-1mlamf20	210	4	is	be	VBZ
cord-016871-1mlamf20	210	5	using	use	VBG
cord-016871-1mlamf20	210	6	only	only	RB
cord-016871-1mlamf20	210	7	male	male	JJ
cord-016871-1mlamf20	210	8	donors	donor	NNS
cord-016871-1mlamf20	210	9	or	or	CC
cord-016871-1mlamf20	210	10	donors	donor	NNS
cord-016871-1mlamf20	210	11	who	who	WP
cord-016871-1mlamf20	210	12	have	have	VBP
cord-016871-1mlamf20	210	13	never	never	RB
cord-016871-1mlamf20	210	14	been	be	VBN
cord-016871-1mlamf20	210	15	pregnant	pregnant	JJ
cord-016871-1mlamf20	210	16	due	due	IN
cord-016871-1mlamf20	210	17	to	to	TO
cord-016871-1mlamf20	210	18	look	look	VB
cord-016871-1mlamf20	210	19	back	back	RB
cord-016871-1mlamf20	210	20	studies	study	NNS
cord-016871-1mlamf20	210	21	showing	show	VBG
cord-016871-1mlamf20	210	22	fewer	few	JJR
cord-016871-1mlamf20	210	23	TRALI	TRALI	NNP
cord-016871-1mlamf20	210	24	events	event	NNS
cord-016871-1mlamf20	210	25	in	in	IN
cord-016871-1mlamf20	210	26	blood	blood	NN
cord-016871-1mlamf20	210	27	donations	donation	NNS
cord-016871-1mlamf20	210	28	from	from	IN
cord-016871-1mlamf20	210	29	those	those	DT
cord-016871-1mlamf20	210	30	populations	population	NNS
cord-016871-1mlamf20	210	31	[	[	-LRB-
cord-016871-1mlamf20	210	32	16	16	CD
cord-016871-1mlamf20	210	33	]	]	-RRB-
cord-016871-1mlamf20	210	34	.	.	.
cord-016871-1mlamf20	211	1	Eder	Eder	NNP
cord-016871-1mlamf20	211	2	et	et	NNP
cord-016871-1mlamf20	211	3	al	al	NNP
cord-016871-1mlamf20	211	4	.	.	NNP
cord-016871-1mlamf20	211	5	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	211	6	that	that	IN
cord-016871-1mlamf20	211	7	preferential	preferential	JJ
cord-016871-1mlamf20	211	8	distribution	distribution	NN
cord-016871-1mlamf20	211	9	of	of	IN
cord-016871-1mlamf20	211	10	plasma	plasma	NN
cord-016871-1mlamf20	211	11	from	from	IN
cord-016871-1mlamf20	211	12	male	male	JJ
cord-016871-1mlamf20	211	13	donors	donor	NNS
cord-016871-1mlamf20	211	14	reduced	reduce	VBD
cord-016871-1mlamf20	211	15	the	the	DT
cord-016871-1mlamf20	211	16	reported	reported	JJ
cord-016871-1mlamf20	211	17	number	number	NN
cord-016871-1mlamf20	211	18	of	of	IN
cord-016871-1mlamf20	211	19	TRALI	TRALI	NNP
cord-016871-1mlamf20	211	20	cases	case	NNS
cord-016871-1mlamf20	211	21	[	[	-LRB-
cord-016871-1mlamf20	211	22	44	44	CD
cord-016871-1mlamf20	211	23	]	]	-RRB-
cord-016871-1mlamf20	211	24	.	.	.
cord-016871-1mlamf20	212	1	Transfusion	transfusion	NN
cord-016871-1mlamf20	212	2	-	-	HYPH
cord-016871-1mlamf20	212	3	associated	associate	VBN
cord-016871-1mlamf20	212	4	immunomodulation	immunomodulation	NN
cord-016871-1mlamf20	212	5	refers	refer	VBZ
cord-016871-1mlamf20	212	6	to	to	IN
cord-016871-1mlamf20	212	7	the	the	DT
cord-016871-1mlamf20	212	8	immunosuppression	immunosuppression	NN
cord-016871-1mlamf20	212	9	resulting	result	VBG
cord-016871-1mlamf20	212	10	from	from	IN
cord-016871-1mlamf20	212	11	the	the	DT
cord-016871-1mlamf20	212	12	introduction	introduction	NN
cord-016871-1mlamf20	212	13	of	of	IN
cord-016871-1mlamf20	212	14	foreign	foreign	JJ
cord-016871-1mlamf20	212	15	antigens	antigen	NNS
cord-016871-1mlamf20	212	16	via	via	IN
cord-016871-1mlamf20	212	17	blood	blood	NN
cord-016871-1mlamf20	212	18	products	product	NNS
cord-016871-1mlamf20	212	19	to	to	IN
cord-016871-1mlamf20	212	20	the	the	DT
cord-016871-1mlamf20	212	21	host	host	NN
cord-016871-1mlamf20	212	22	[	[	-LRB-
cord-016871-1mlamf20	212	23	25	25	CD
cord-016871-1mlamf20	212	24	]	]	-RRB-
cord-016871-1mlamf20	212	25	.	.	.
cord-016871-1mlamf20	213	1	The	the	DT
cord-016871-1mlamf20	213	2	exact	exact	JJ
cord-016871-1mlamf20	213	3	mechanism	mechanism	NN
cord-016871-1mlamf20	213	4	of	of	IN
cord-016871-1mlamf20	213	5	this	this	DT
cord-016871-1mlamf20	213	6	effect	effect	NN
cord-016871-1mlamf20	213	7	has	have	VBZ
cord-016871-1mlamf20	213	8	not	not	RB
cord-016871-1mlamf20	213	9	yet	yet	RB
cord-016871-1mlamf20	213	10	been	be	VBN
cord-016871-1mlamf20	213	11	elucidated	elucidate	VBN
cord-016871-1mlamf20	213	12	,	,	,
cord-016871-1mlamf20	213	13	but	but	CC
cord-016871-1mlamf20	213	14	plasma	plasma	NN
cord-016871-1mlamf20	213	15	components	component	NNS
cord-016871-1mlamf20	213	16	,	,	,
cord-016871-1mlamf20	213	17	white	white	JJ
cord-016871-1mlamf20	213	18	blood	blood	NN
cord-016871-1mlamf20	213	19	cells	cell	NNS
cord-016871-1mlamf20	213	20	(	(	-LRB-
cord-016871-1mlamf20	213	21	WBCs	WBCs	NNP
cord-016871-1mlamf20	213	22	)	)	-RRB-
cord-016871-1mlamf20	213	23	,	,	,
cord-016871-1mlamf20	213	24	metabolic	metabolic	JJ
cord-016871-1mlamf20	213	25	products	product	NNS
cord-016871-1mlamf20	213	26	from	from	IN
cord-016871-1mlamf20	213	27	storage	storage	NN
cord-016871-1mlamf20	213	28	processes	process	NNS
cord-016871-1mlamf20	213	29	are	be	VBP
cord-016871-1mlamf20	213	30	thought	think	VBN
cord-016871-1mlamf20	213	31	to	to	TO
cord-016871-1mlamf20	213	32	play	play	VB
cord-016871-1mlamf20	213	33	a	a	DT
cord-016871-1mlamf20	213	34	role	role	NN
cord-016871-1mlamf20	213	35	.	.	.
cord-016871-1mlamf20	214	1	This	this	DT
cord-016871-1mlamf20	214	2	effect	effect	NN
cord-016871-1mlamf20	214	3	may	may	MD
cord-016871-1mlamf20	214	4	be	be	VB
cord-016871-1mlamf20	214	5	responsible	responsible	JJ
cord-016871-1mlamf20	214	6	for	for	IN
cord-016871-1mlamf20	214	7	the	the	DT
cord-016871-1mlamf20	214	8	immunosuppressive	immunosuppressive	JJ
cord-016871-1mlamf20	214	9	effects	effect	NNS
cord-016871-1mlamf20	214	10	of	of	IN
cord-016871-1mlamf20	214	11	transfusions	transfusion	NNS
cord-016871-1mlamf20	214	12	on	on	IN
cord-016871-1mlamf20	214	13	severely	severely	RB
cord-016871-1mlamf20	214	14	ill	ill	JJ
cord-016871-1mlamf20	214	15	patients	patient	NNS
cord-016871-1mlamf20	214	16	.	.	.
cord-016871-1mlamf20	215	1	Transfusions	transfusion	NNS
cord-016871-1mlamf20	215	2	can	can	MD
cord-016871-1mlamf20	215	3	cause	cause	VB
cord-016871-1mlamf20	215	4	sensitization	sensitization	NN
cord-016871-1mlamf20	215	5	to	to	IN
cord-016871-1mlamf20	215	6	HLA	HLA	NNP
cord-016871-1mlamf20	215	7	antigens	antigen	NNS
cord-016871-1mlamf20	215	8	,	,	,
cord-016871-1mlamf20	215	9	creating	create	VBG
cord-016871-1mlamf20	215	10	a	a	DT
cord-016871-1mlamf20	215	11	unique	unique	JJ
cord-016871-1mlamf20	215	12	problem	problem	NN
cord-016871-1mlamf20	215	13	in	in	IN
cord-016871-1mlamf20	215	14	potential	potential	JJ
cord-016871-1mlamf20	215	15	kidney	kidney	NN
cord-016871-1mlamf20	215	16	transplant	transplant	NN
cord-016871-1mlamf20	215	17	patients	patient	NNS
cord-016871-1mlamf20	215	18	.	.	.
cord-016871-1mlamf20	216	1	Studies	study	NNS
cord-016871-1mlamf20	216	2	have	have	VBP
cord-016871-1mlamf20	216	3	demonstrated	demonstrate	VBN
cord-016871-1mlamf20	216	4	increased	increase	VBN
cord-016871-1mlamf20	216	5	sensitization	sensitization	NN
cord-016871-1mlamf20	216	6	of	of	IN
cord-016871-1mlamf20	216	7	patients	patient	NNS
cord-016871-1mlamf20	216	8	on	on	IN
cord-016871-1mlamf20	216	9	a	a	DT
cord-016871-1mlamf20	216	10	kidney	kidney	NN
cord-016871-1mlamf20	216	11	transplant	transplant	NN
cord-016871-1mlamf20	216	12	waiting	waiting	NN
cord-016871-1mlamf20	216	13	list	list	NN
cord-016871-1mlamf20	216	14	after	after	IN
cord-016871-1mlamf20	216	15	transfusion	transfusion	NN
cord-016871-1mlamf20	216	16	,	,	,
cord-016871-1mlamf20	216	17	rendering	render	VBG
cord-016871-1mlamf20	216	18	them	-PRON-	PRP
cord-016871-1mlamf20	216	19	unsuitable	unsuitable	JJ
cord-016871-1mlamf20	216	20	candidates	candidate	NNS
cord-016871-1mlamf20	216	21	for	for	IN
cord-016871-1mlamf20	216	22	living	live	VBG
cord-016871-1mlamf20	216	23	donation	donation	NN
cord-016871-1mlamf20	216	24	.	.	.
cord-016871-1mlamf20	217	1	Their	-PRON-	PRP$
cord-016871-1mlamf20	217	2	only	only	RB
cord-016871-1mlamf20	217	3	remaining	remain	VBG
cord-016871-1mlamf20	217	4	alternative	alternative	NN
cord-016871-1mlamf20	217	5	once	once	IN
cord-016871-1mlamf20	217	6	this	this	DT
cord-016871-1mlamf20	217	7	has	have	VBZ
cord-016871-1mlamf20	217	8	occurred	occur	VBN
cord-016871-1mlamf20	217	9	is	be	VBZ
cord-016871-1mlamf20	217	10	to	to	TO
cord-016871-1mlamf20	217	11	wait	wait	VB
cord-016871-1mlamf20	217	12	for	for	IN
cord-016871-1mlamf20	217	13	a	a	DT
cord-016871-1mlamf20	217	14	cadaveric	cadaveric	JJ
cord-016871-1mlamf20	217	15	graft	graft	NN
cord-016871-1mlamf20	217	16	,	,	,
cord-016871-1mlamf20	217	17	which	which	WDT
cord-016871-1mlamf20	217	18	takes	take	VBZ
cord-016871-1mlamf20	217	19	up	up	RP
cord-016871-1mlamf20	217	20	to	to	TO
cord-016871-1mlamf20	217	21	four	four	CD
cord-016871-1mlamf20	217	22	times	time	NNS
cord-016871-1mlamf20	217	23	longer	long	RBR
cord-016871-1mlamf20	217	24	,	,	,
cord-016871-1mlamf20	217	25	and	and	CC
cord-016871-1mlamf20	217	26	may	may	MD
cord-016871-1mlamf20	217	27	never	never	RB
cord-016871-1mlamf20	217	28	receive	receive	VB
cord-016871-1mlamf20	217	29	a	a	DT
cord-016871-1mlamf20	217	30	transplant	transplant	NN
cord-016871-1mlamf20	217	31	.	.	.
cord-016871-1mlamf20	218	1	Hence	hence	RB
cord-016871-1mlamf20	218	2	,	,	,
cord-016871-1mlamf20	218	3	non	non	JJ
cord-016871-1mlamf20	218	4	-	-	JJ
cord-016871-1mlamf20	218	5	life	life	JJ
cord-016871-1mlamf20	218	6	-	-	HYPH
cord-016871-1mlamf20	218	7	sustaining	sustain	VBG
cord-016871-1mlamf20	218	8	transfusions	transfusion	NNS
cord-016871-1mlamf20	218	9	should	should	MD
cord-016871-1mlamf20	218	10	be	be	VB
cord-016871-1mlamf20	218	11	avoided	avoid	VBN
cord-016871-1mlamf20	218	12	in	in	IN
cord-016871-1mlamf20	218	13	potential	potential	JJ
cord-016871-1mlamf20	218	14	kidney	kidney	NN
cord-016871-1mlamf20	218	15	transplant	transplant	NN
cord-016871-1mlamf20	218	16	recipients	recipient	NNS
cord-016871-1mlamf20	218	17	[	[	-LRB-
cord-016871-1mlamf20	218	18	25	25	CD
cord-016871-1mlamf20	218	19	]	]	-RRB-
cord-016871-1mlamf20	218	20	.	.	.
cord-016871-1mlamf20	219	1	Red	red	JJ
cord-016871-1mlamf20	219	2	blood	blood	NN
cord-016871-1mlamf20	219	3	cell	cell	NN
cord-016871-1mlamf20	219	4	transfusion	transfusion	NN
cord-016871-1mlamf20	219	5	is	be	VBZ
cord-016871-1mlamf20	219	6	an	an	DT
cord-016871-1mlamf20	219	7	independent	independent	JJ
cord-016871-1mlamf20	219	8	predictor	predictor	NN
cord-016871-1mlamf20	219	9	of	of	IN
cord-016871-1mlamf20	219	10	systemic	systemic	NN
cord-016871-1mlamf20	219	11	in	in	IN
cord-016871-1mlamf20	219	12	fl	fl	NNP
cord-016871-1mlamf20	219	13	ammatory	ammatory	NNP
cord-016871-1mlamf20	219	14	response	response	NN
cord-016871-1mlamf20	219	15	syndrome	syndrome	NN
cord-016871-1mlamf20	219	16	(	(	-LRB-
cord-016871-1mlamf20	219	17	SIRS	SIRS	NNP
cord-016871-1mlamf20	219	18	)	)	-RRB-
cord-016871-1mlamf20	219	19	,	,	,
cord-016871-1mlamf20	219	20	ICU	ICU	NNP
cord-016871-1mlamf20	219	21	admission	admission	NN
cord-016871-1mlamf20	219	22	,	,	,
cord-016871-1mlamf20	219	23	mortality	mortality	NN
cord-016871-1mlamf20	219	24	,	,	,
cord-016871-1mlamf20	219	25	and	and	CC
cord-016871-1mlamf20	219	26	length	length	NN
cord-016871-1mlamf20	219	27	of	of	IN
cord-016871-1mlamf20	219	28	hospital	hospital	NN
cord-016871-1mlamf20	219	29	stay	stay	NN
cord-016871-1mlamf20	219	30	,	,	,
cord-016871-1mlamf20	219	31	and	and	CC
cord-016871-1mlamf20	219	32	the	the	DT
cord-016871-1mlamf20	219	33	development	development	NN
cord-016871-1mlamf20	219	34	of	of	IN
cord-016871-1mlamf20	219	35	multiple	multiple	JJ
cord-016871-1mlamf20	219	36	organ	organ	NN
cord-016871-1mlamf20	219	37	failure	failure	NN
cord-016871-1mlamf20	219	38	(	(	-LRB-
cord-016871-1mlamf20	219	39	MOF	MOF	NNP
cord-016871-1mlamf20	219	40	)	)	-RRB-
cord-016871-1mlamf20	219	41	[	[	-LRB-
cord-016871-1mlamf20	219	42	45	45	CD
cord-016871-1mlamf20	219	43	]	]	-RRB-
cord-016871-1mlamf20	219	44	.	.	.
cord-016871-1mlamf20	220	1	In	in	IN
cord-016871-1mlamf20	220	2	particular	particular	JJ
cord-016871-1mlamf20	220	3	,	,	,
cord-016871-1mlamf20	220	4	the	the	DT
cord-016871-1mlamf20	220	5	age	age	NN
cord-016871-1mlamf20	220	6	of	of	IN
cord-016871-1mlamf20	220	7	the	the	DT
cord-016871-1mlamf20	220	8	blood	blood	NN
cord-016871-1mlamf20	220	9	plays	play	VBZ
cord-016871-1mlamf20	220	10	an	an	DT
cord-016871-1mlamf20	220	11	important	important	JJ
cord-016871-1mlamf20	220	12	role	role	NN
cord-016871-1mlamf20	220	13	,	,	,
cord-016871-1mlamf20	220	14	with	with	IN
cord-016871-1mlamf20	220	15	increased	increase	VBN
cord-016871-1mlamf20	220	16	age	age	NN
cord-016871-1mlamf20	220	17	of	of	IN
cord-016871-1mlamf20	220	18	RBCs	rbc	NNS
cord-016871-1mlamf20	220	19	resulting	result	VBG
cord-016871-1mlamf20	220	20	in	in	IN
cord-016871-1mlamf20	220	21	increased	increase	VBN
cord-016871-1mlamf20	220	22	instances	instance	NNS
cord-016871-1mlamf20	220	23	of	of	IN
cord-016871-1mlamf20	220	24	MOF	MOF	NNP
cord-016871-1mlamf20	220	25	.	.	.
cord-016871-1mlamf20	221	1	RBCs	rbc	NNS
cord-016871-1mlamf20	221	2	are	be	VBP
cord-016871-1mlamf20	221	3	not	not	RB
cord-016871-1mlamf20	221	4	alone	alone	JJ
cord-016871-1mlamf20	221	5	in	in	IN
cord-016871-1mlamf20	221	6	this	this	DT
cord-016871-1mlamf20	221	7	adverse	adverse	JJ
cord-016871-1mlamf20	221	8	event	event	NN
cord-016871-1mlamf20	221	9	.	.	.
cord-016871-1mlamf20	222	1	A	a	DT
cord-016871-1mlamf20	222	2	multicenter	multicenter	JJ
cord-016871-1mlamf20	222	3	prospective	prospective	JJ
cord-016871-1mlamf20	222	4	cohort	cohort	NN
cord-016871-1mlamf20	222	5	study	study	NN
cord-016871-1mlamf20	222	6	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	222	7	that	that	IN
cord-016871-1mlamf20	222	8	FFP	FFP	NNP
cord-016871-1mlamf20	222	9	was	be	VBD
cord-016871-1mlamf20	222	10	independently	independently	RB
cord-016871-1mlamf20	222	11	associated	associate	VBN
cord-016871-1mlamf20	222	12	with	with	IN
cord-016871-1mlamf20	222	13	increased	increase	VBN
cord-016871-1mlamf20	222	14	risk	risk	NN
cord-016871-1mlamf20	222	15	of	of	IN
cord-016871-1mlamf20	222	16	MOF	MOF	NNP
cord-016871-1mlamf20	222	17	and	and	CC
cord-016871-1mlamf20	222	18	acute	acute	JJ
cord-016871-1mlamf20	222	19	respiratory	respiratory	JJ
cord-016871-1mlamf20	222	20	distress	distress	NN
cord-016871-1mlamf20	222	21	syndrome	syndrome	NN
cord-016871-1mlamf20	222	22	(	(	-LRB-
cord-016871-1mlamf20	222	23	ARDS	ARDS	NNP
cord-016871-1mlamf20	222	24	)	)	-RRB-
cord-016871-1mlamf20	222	25	of	of	IN
cord-016871-1mlamf20	222	26	2.1	2.1	CD
cord-016871-1mlamf20	222	27	%	%	NN
cord-016871-1mlamf20	222	28	and	and	CC
cord-016871-1mlamf20	222	29	2.5	2.5	CD
cord-016871-1mlamf20	222	30	%	%	NN
cord-016871-1mlamf20	222	31	[	[	-LRB-
cord-016871-1mlamf20	222	32	46	46	CD
cord-016871-1mlamf20	222	33	]	]	-RRB-
cord-016871-1mlamf20	222	34	.	.	.
cord-016871-1mlamf20	223	1	The	the	DT
cord-016871-1mlamf20	223	2	same	same	JJ
cord-016871-1mlamf20	223	3	study	study	NN
cord-016871-1mlamf20	223	4	found	find	VBD
cord-016871-1mlamf20	223	5	,	,	,
cord-016871-1mlamf20	223	6	however	however	RB
cord-016871-1mlamf20	223	7	,	,	,
cord-016871-1mlamf20	223	8	decreased	decrease	VBD
cord-016871-1mlamf20	223	9	risk	risk	NN
cord-016871-1mlamf20	223	10	of	of	IN
cord-016871-1mlamf20	223	11	MOF	MOF	NNP
cord-016871-1mlamf20	223	12	per	per	IN
cord-016871-1mlamf20	223	13	unit	unit	NN
cord-016871-1mlamf20	223	14	of	of	IN
cord-016871-1mlamf20	223	15	cryoprecipitate	cryoprecipitate	NNP
cord-016871-1mlamf20	223	16	,	,	,
cord-016871-1mlamf20	223	17	and	and	CC
cord-016871-1mlamf20	223	18	platelets	platelet	NNS
cord-016871-1mlamf20	223	19	were	be	VBD
cord-016871-1mlamf20	223	20	not	not	RB
cord-016871-1mlamf20	223	21	found	find	VBN
cord-016871-1mlamf20	223	22	to	to	TO
cord-016871-1mlamf20	223	23	be	be	VB
cord-016871-1mlamf20	223	24	associated	associate	VBN
cord-016871-1mlamf20	223	25	with	with	IN
cord-016871-1mlamf20	223	26	MOF	MOF	NNP
cord-016871-1mlamf20	223	27	or	or	CC
cord-016871-1mlamf20	223	28	ARDS	ARDS	NNP
cord-016871-1mlamf20	223	29	[	[	-LRB-
cord-016871-1mlamf20	223	30	46	46	CD
cord-016871-1mlamf20	223	31	]	]	-RRB-
cord-016871-1mlamf20	223	32	.	.	.
cord-016871-1mlamf20	224	1	In	in	IN
cord-016871-1mlamf20	224	2	addition	addition	NN
cord-016871-1mlamf20	224	3	to	to	IN
cord-016871-1mlamf20	224	4	MOF	MOF	NNP
cord-016871-1mlamf20	224	5	,	,	,
cord-016871-1mlamf20	224	6	blood	blood	NN
cord-016871-1mlamf20	224	7	transfusions	transfusion	NNS
cord-016871-1mlamf20	224	8	are	be	VBP
cord-016871-1mlamf20	224	9	notorious	notorious	JJ
cord-016871-1mlamf20	224	10	in	in	IN
cord-016871-1mlamf20	224	11	lay	lay	JJ
cord-016871-1mlamf20	224	12	media	medium	NNS
cord-016871-1mlamf20	224	13	for	for	IN
cord-016871-1mlamf20	224	14	their	-PRON-	PRP$
cord-016871-1mlamf20	224	15	association	association	NN
cord-016871-1mlamf20	224	16	with	with	IN
cord-016871-1mlamf20	224	17	infectious	infectious	JJ
cord-016871-1mlamf20	224	18	agents	agent	NNS
cord-016871-1mlamf20	224	19	.	.	.
cord-016871-1mlamf20	225	1	In	in	IN
cord-016871-1mlamf20	225	2	their	-PRON-	PRP$
cord-016871-1mlamf20	225	3	review	review	NN
cord-016871-1mlamf20	225	4	of	of	IN
cord-016871-1mlamf20	225	5	the	the	DT
cord-016871-1mlamf20	225	6	current	current	JJ
cord-016871-1mlamf20	225	7	literature	literature	NN
cord-016871-1mlamf20	225	8	,	,	,
cord-016871-1mlamf20	225	9	Englesbe	Englesbe	NNP
cord-016871-1mlamf20	225	10	et	et	NNP
cord-016871-1mlamf20	225	11	al	al	NNP
cord-016871-1mlamf20	225	12	.	.	NNP
cord-016871-1mlamf20	225	13	found	find	VBD
cord-016871-1mlamf20	225	14	that	that	IN
cord-016871-1mlamf20	225	15	patients	patient	NNS
cord-016871-1mlamf20	225	16	who	who	WP
cord-016871-1mlamf20	225	17	received	receive	VBD
cord-016871-1mlamf20	225	18	transfusions	transfusion	NNS
cord-016871-1mlamf20	225	19	compared	compare	VBN
cord-016871-1mlamf20	225	20	to	to	IN
cord-016871-1mlamf20	225	21	those	those	DT
cord-016871-1mlamf20	225	22	who	who	WP
cord-016871-1mlamf20	225	23	did	do	VBD
cord-016871-1mlamf20	225	24	not	not	RB
cord-016871-1mlamf20	225	25	experienced	experience	VBN
cord-016871-1mlamf20	225	26	signi	signi	NNP
cord-016871-1mlamf20	225	27	fi	fi	NN
cord-016871-1mlamf20	225	28	ca	can	MD
cord-016871-1mlamf20	225	29	nt	not	RB
cord-016871-1mlamf20	225	30	increase	increase	VB
cord-016871-1mlamf20	225	31	nosocomial	nosocomial	JJ
cord-016871-1mlamf20	225	32	infection	infection	NN
cord-016871-1mlamf20	225	33	rates	rate	NNS
cord-016871-1mlamf20	225	34	,	,	,
cord-016871-1mlamf20	225	35	and	and	CC
cord-016871-1mlamf20	225	36	each	each	DT
cord-016871-1mlamf20	225	37	additional	additional	JJ
cord-016871-1mlamf20	225	38	pRBC	prbc	JJ
cord-016871-1mlamf20	225	39	transfused	transfuse	VBN
cord-016871-1mlamf20	225	40	correlated	correlate	VBN
cord-016871-1mlamf20	225	41	to	to	IN
cord-016871-1mlamf20	225	42	increased	increase	VBN
cord-016871-1mlamf20	225	43	infection	infection	NN
cord-016871-1mlamf20	225	44	risk	risk	NN
cord-016871-1mlamf20	225	45	[	[	-LRB-
cord-016871-1mlamf20	225	46	25	25	CD
cord-016871-1mlamf20	225	47	]	]	-RRB-
cord-016871-1mlamf20	225	48	.	.	.
cord-016871-1mlamf20	226	1	Staphylococcus	Staphylococcus	NNP
cord-016871-1mlamf20	226	2	aureus	aureus	NN
cord-016871-1mlamf20	226	3	is	be	VBZ
cord-016871-1mlamf20	226	4	the	the	DT
cord-016871-1mlamf20	226	5	most	most	RBS
cord-016871-1mlamf20	226	6	commonly	commonly	RB
cord-016871-1mlamf20	226	7	transmitted	transmit	VBN
cord-016871-1mlamf20	226	8	bacterial	bacterial	JJ
cord-016871-1mlamf20	226	9	pathogen	pathogen	NN
cord-016871-1mlamf20	226	10	[	[	-LRB-
cord-016871-1mlamf20	226	11	16	16	CD
cord-016871-1mlamf20	226	12	]	]	-RRB-
cord-016871-1mlamf20	226	13	.	.	.
cord-016871-1mlamf20	227	1	Bacterial	bacterial	JJ
cord-016871-1mlamf20	227	2	pathogen	pathogen	NN
cord-016871-1mlamf20	227	3	in	in	IN
cord-016871-1mlamf20	227	4	blood	blood	NN
cord-016871-1mlamf20	227	5	products	product	NNS
cord-016871-1mlamf20	227	6	arise	arise	VBP
cord-016871-1mlamf20	227	7	mainly	mainly	RB
cord-016871-1mlamf20	227	8	from	from	IN
cord-016871-1mlamf20	227	9	donor	donor	NN
cord-016871-1mlamf20	227	10	skin	skin	NN
cord-016871-1mlamf20	227	11	,	,	,
cord-016871-1mlamf20	227	12	and	and	CC
cord-016871-1mlamf20	227	13	platelets	platelet	NNS
cord-016871-1mlamf20	227	14	are	be	VBP
cord-016871-1mlamf20	227	15	especially	especially	RB
cord-016871-1mlamf20	227	16	prone	prone	JJ
cord-016871-1mlamf20	227	17	to	to	IN
cord-016871-1mlamf20	227	18	these	these	DT
cord-016871-1mlamf20	227	19	contaminants	contaminant	NNS
cord-016871-1mlamf20	227	20	[	[	-LRB-
cord-016871-1mlamf20	227	21	35	35	CD
cord-016871-1mlamf20	227	22	]	]	-RRB-
cord-016871-1mlamf20	227	23	.	.	.
cord-016871-1mlamf20	228	1	However	however	RB
cord-016871-1mlamf20	228	2	,	,	,
cord-016871-1mlamf20	228	3	bacterial	bacterial	JJ
cord-016871-1mlamf20	228	4	infections	infection	NNS
cord-016871-1mlamf20	228	5	are	be	VBP
cord-016871-1mlamf20	228	6	less	less	RBR
cord-016871-1mlamf20	228	7	common	common	JJ
cord-016871-1mlamf20	228	8	than	than	IN
cord-016871-1mlamf20	228	9	viral	viral	JJ
cord-016871-1mlamf20	228	10	infections	infection	NNS
cord-016871-1mlamf20	228	11	in	in	IN
cord-016871-1mlamf20	228	12	blood	blood	NN
cord-016871-1mlamf20	228	13	transfusions	transfusion	NNS
cord-016871-1mlamf20	228	14	.	.	.
cord-016871-1mlamf20	229	1	Despite	despite	IN
cord-016871-1mlamf20	229	2	increased	increase	VBN
cord-016871-1mlamf20	229	3	screening	screening	NN
cord-016871-1mlamf20	229	4	and	and	CC
cord-016871-1mlamf20	229	5	testing	testing	NN
cord-016871-1mlamf20	229	6	,	,	,
cord-016871-1mlamf20	229	7	each	each	DT
cord-016871-1mlamf20	229	8	RBC	RBC	NNP
cord-016871-1mlamf20	229	9	transfusion	transfusion	NN
cord-016871-1mlamf20	229	10	is	be	VBZ
cord-016871-1mlamf20	229	11	associated	associate	VBN
cord-016871-1mlamf20	229	12	with	with	IN
cord-016871-1mlamf20	229	13	a	a	DT
cord-016871-1mlamf20	229	14	risk	risk	NN
cord-016871-1mlamf20	229	15	for	for	IN
cord-016871-1mlamf20	229	16	viral	viral	JJ
cord-016871-1mlamf20	229	17	infections	infection	NNS
cord-016871-1mlamf20	229	18	such	such	JJ
cord-016871-1mlamf20	229	19	as	as	IN
cord-016871-1mlamf20	229	20	hepatitis	hepatitis	NNP
cord-016871-1mlamf20	229	21	[	[	-LRB-
cord-016871-1mlamf20	229	22	29	29	CD
cord-016871-1mlamf20	229	23	]	]	-RRB-
cord-016871-1mlamf20	229	24	.	.	.
cord-016871-1mlamf20	230	1	Virus	virus	NN
cord-016871-1mlamf20	230	2	risks	risk	VBZ
cord-016871-1mlamf20	230	3	in	in	IN
cord-016871-1mlamf20	230	4	the	the	DT
cord-016871-1mlamf20	230	5	UK	UK	NNP
cord-016871-1mlamf20	230	6	in	in	IN
cord-016871-1mlamf20	230	7	FFP	FFP	NNP
cord-016871-1mlamf20	230	8	have	have	VBP
cord-016871-1mlamf20	230	9	been	be	VBN
cord-016871-1mlamf20	230	10	estimated	estimate	VBN
cord-016871-1mlamf20	230	11	at	at	IN
cord-016871-1mlamf20	230	12	1	1	CD
cord-016871-1mlamf20	230	13	in	in	IN
cord-016871-1mlamf20	230	14	8	8	CD
cord-016871-1mlamf20	230	15	million	million	CD
cord-016871-1mlamf20	230	16	for	for	IN
cord-016871-1mlamf20	230	17	HIV	HIV	NNP
cord-016871-1mlamf20	230	18	,	,	,
cord-016871-1mlamf20	230	19	1	1	CD
cord-016871-1mlamf20	230	20	in	in	IN
cord-016871-1mlamf20	230	21	30	30	CD
cord-016871-1mlamf20	230	22	million	million	CD
cord-016871-1mlamf20	230	23	for	for	IN
cord-016871-1mlamf20	230	24	HCV	HCV	NNP
cord-016871-1mlamf20	230	25	and	and	CC
cord-016871-1mlamf20	230	26	1	1	CD
cord-016871-1mlamf20	230	27	in	in	IN
cord-016871-1mlamf20	230	28	900,000	900,000	CD
cord-016871-1mlamf20	230	29	for	for	IN
cord-016871-1mlamf20	230	30	HBV	HBV	NNP
cord-016871-1mlamf20	230	31	[	[	-LRB-
cord-016871-1mlamf20	230	32	35	35	CD
cord-016871-1mlamf20	230	33	]	]	-RRB-
cord-016871-1mlamf20	230	34	.	.	.
cord-016871-1mlamf20	231	1	Since	since	IN
cord-016871-1mlamf20	231	2	up	up	IN
cord-016871-1mlamf20	231	3	to	to	TO
cord-016871-1mlamf20	231	4	50	50	CD
cord-016871-1mlamf20	231	5	%	%	NN
cord-016871-1mlamf20	231	6	of	of	IN
cord-016871-1mlamf20	231	7	adult	adult	NN
cord-016871-1mlamf20	231	8	donors	donor	NNS
cord-016871-1mlamf20	231	9	are	be	VBP
cord-016871-1mlamf20	231	10	cytomegalovirus	cytomegalovirus	JJ
cord-016871-1mlamf20	231	11	(	(	-LRB-
cord-016871-1mlamf20	231	12	CMV	CMV	NNP
cord-016871-1mlamf20	231	13	)	)	-RRB-
cord-016871-1mlamf20	231	14	carriers	carrier	NNS
cord-016871-1mlamf20	231	15	,	,	,
cord-016871-1mlamf20	231	16	there	there	EX
cord-016871-1mlamf20	231	17	is	be	VBZ
cord-016871-1mlamf20	231	18	a	a	DT
cord-016871-1mlamf20	231	19	risk	risk	NN
cord-016871-1mlamf20	231	20	of	of	IN
cord-016871-1mlamf20	231	21	transmission	transmission	NN
cord-016871-1mlamf20	231	22	of	of	IN
cord-016871-1mlamf20	231	23	this	this	DT
cord-016871-1mlamf20	231	24	virus	virus	NN
cord-016871-1mlamf20	231	25	to	to	IN
cord-016871-1mlamf20	231	26	patients	patient	NNS
cord-016871-1mlamf20	231	27	,	,	,
cord-016871-1mlamf20	231	28	especially	especially	RB
cord-016871-1mlamf20	231	29	the	the	DT
cord-016871-1mlamf20	231	30	immunosuppressed	immunosuppressed	JJ
cord-016871-1mlamf20	231	31	,	,	,
cord-016871-1mlamf20	231	32	transplant	transplant	NN
cord-016871-1mlamf20	231	33	patients	patient	NNS
cord-016871-1mlamf20	231	34	and	and	CC
cord-016871-1mlamf20	231	35	neonates	neonate	NNS
cord-016871-1mlamf20	231	36	[	[	-LRB-
cord-016871-1mlamf20	231	37	35	35	CD
cord-016871-1mlamf20	231	38	]	]	-RRB-
cord-016871-1mlamf20	231	39	.	.	.
cord-016871-1mlamf20	232	1	Compared	compare	VBN
cord-016871-1mlamf20	232	2	to	to	IN
cord-016871-1mlamf20	232	3	viral	viral	JJ
cord-016871-1mlamf20	232	4	causes	cause	NNS
cord-016871-1mlamf20	232	5	,	,	,
cord-016871-1mlamf20	232	6	bacterial	bacterial	JJ
cord-016871-1mlamf20	232	7	,	,	,
cord-016871-1mlamf20	232	8	endotoxin	endotoxin	NN
cord-016871-1mlamf20	232	9	and	and	CC
cord-016871-1mlamf20	232	10	prion	prion	NN
cord-016871-1mlamf20	232	11	contamination	contamination	NN
cord-016871-1mlamf20	232	12	rates	rate	NNS
cord-016871-1mlamf20	232	13	are	be	VBP
cord-016871-1mlamf20	232	14	more	more	RBR
cord-016871-1mlamf20	232	15	rare	rare	JJ
cord-016871-1mlamf20	232	16	[	[	-LRB-
cord-016871-1mlamf20	232	17	35	35	CD
cord-016871-1mlamf20	232	18	]	]	-RRB-
cord-016871-1mlamf20	232	19	.	.	.
cord-016871-1mlamf20	233	1	In	in	IN
cord-016871-1mlamf20	233	2	order	order	NN
cord-016871-1mlamf20	233	3	to	to	TO
cord-016871-1mlamf20	233	4	avoid	avoid	VB
cord-016871-1mlamf20	233	5	this	this	DT
cord-016871-1mlamf20	233	6	deleterious	deleterious	JJ
cord-016871-1mlamf20	233	7	complication	complication	NN
cord-016871-1mlamf20	233	8	,	,	,
cord-016871-1mlamf20	233	9	virus	virus	NN
cord-016871-1mlamf20	233	10	-	-	HYPH
cord-016871-1mlamf20	233	11	inactivated	inactivate	VBN
cord-016871-1mlamf20	233	12	preparations	preparation	NNS
cord-016871-1mlamf20	233	13	of	of	IN
cord-016871-1mlamf20	233	14	plasma	plasma	NN
cord-016871-1mlamf20	233	15	exist	exist	VBP
cord-016871-1mlamf20	233	16	,	,	,
cord-016871-1mlamf20	233	17	such	such	JJ
cord-016871-1mlamf20	233	18	as	as	IN
cord-016871-1mlamf20	233	19	methylene	methylene	NN
cord-016871-1mlamf20	233	20	blue	blue	JJ
cord-016871-1mlamf20	233	21	and	and	CC
cord-016871-1mlamf20	233	22	solventdetergent	solventdetergent	JJ
cord-016871-1mlamf20	233	23	treated	treat	VBN
cord-016871-1mlamf20	233	24	products	product	NNS
cord-016871-1mlamf20	233	25	.	.	.
cord-016871-1mlamf20	234	1	While	while	IN
cord-016871-1mlamf20	234	2	these	these	DT
cord-016871-1mlamf20	234	3	options	option	NNS
cord-016871-1mlamf20	234	4	may	may	MD
cord-016871-1mlamf20	234	5	offer	offer	VB
cord-016871-1mlamf20	234	6	increased	increase	VBN
cord-016871-1mlamf20	234	7	viral	viral	JJ
cord-016871-1mlamf20	234	8	protection	protection	NN
cord-016871-1mlamf20	234	9	,	,	,
cord-016871-1mlamf20	234	10	they	-PRON-	PRP
cord-016871-1mlamf20	234	11	have	have	VBP
cord-016871-1mlamf20	234	12	been	be	VBN
cord-016871-1mlamf20	234	13	associated	associate	VBN
cord-016871-1mlamf20	234	14	with	with	IN
cord-016871-1mlamf20	234	15	loss	loss	NN
cord-016871-1mlamf20	234	16	of	of	IN
cord-016871-1mlamf20	234	17	clotting	clotting	NN
cord-016871-1mlamf20	234	18	factors	factor	NNS
cord-016871-1mlamf20	234	19	[	[	-LRB-
cord-016871-1mlamf20	234	20	35	35	CD
cord-016871-1mlamf20	234	21	]	]	-RRB-
cord-016871-1mlamf20	234	22	.	.	.
cord-016871-1mlamf20	235	1	The	the	DT
cord-016871-1mlamf20	235	2	most	most	RBS
cord-016871-1mlamf20	235	3	stringent	stringent	JJ
cord-016871-1mlamf20	235	4	testing	testing	NN
cord-016871-1mlamf20	235	5	protocols	protocol	NNS
cord-016871-1mlamf20	235	6	and	and	CC
cord-016871-1mlamf20	235	7	sensitive	sensitive	JJ
cord-016871-1mlamf20	235	8	tests	test	NNS
cord-016871-1mlamf20	235	9	may	may	MD
cord-016871-1mlamf20	235	10	not	not	RB
cord-016871-1mlamf20	235	11	ever	ever	RB
cord-016871-1mlamf20	235	12	eradicate	eradicate	VB
cord-016871-1mlamf20	235	13	the	the	DT
cord-016871-1mlamf20	235	14	risk	risk	NN
cord-016871-1mlamf20	235	15	of	of	IN
cord-016871-1mlamf20	235	16	infectious	infectious	JJ
cord-016871-1mlamf20	235	17	agent	agent	NN
cord-016871-1mlamf20	235	18	transmission	transmission	NN
cord-016871-1mlamf20	235	19	due	due	IN
cord-016871-1mlamf20	235	20	to	to	IN
cord-016871-1mlamf20	235	21	several	several	JJ
cord-016871-1mlamf20	235	22	reasons	reason	NNS
cord-016871-1mlamf20	235	23	.	.	.
cord-016871-1mlamf20	236	1	First	first	RB
cord-016871-1mlamf20	236	2	,	,	,
cord-016871-1mlamf20	236	3	new	new	JJ
cord-016871-1mlamf20	236	4	pathogens	pathogen	NNS
cord-016871-1mlamf20	236	5	of	of	IN
cord-016871-1mlamf20	236	6	unknown	unknown	JJ
cord-016871-1mlamf20	236	7	methods	method	NNS
cord-016871-1mlamf20	236	8	of	of	IN
cord-016871-1mlamf20	236	9	spread	spread	NN
cord-016871-1mlamf20	236	10	are	be	VBP
cord-016871-1mlamf20	236	11	constantly	constantly	RB
cord-016871-1mlamf20	236	12	emerging	emerge	VBG
cord-016871-1mlamf20	236	13	and	and	CC
cord-016871-1mlamf20	236	14	may	may	MD
cord-016871-1mlamf20	236	15	not	not	RB
cord-016871-1mlamf20	236	16	actively	actively	RB
cord-016871-1mlamf20	236	17	be	be	VB
cord-016871-1mlamf20	236	18	screened	screen	VBN
cord-016871-1mlamf20	236	19	for	for	IN
cord-016871-1mlamf20	236	20	in	in	IN
cord-016871-1mlamf20	236	21	its	-PRON-	PRP$
cord-016871-1mlamf20	236	22	early	early	JJ
cord-016871-1mlamf20	236	23	emergence	emergence	NN
cord-016871-1mlamf20	236	24	,	,	,
cord-016871-1mlamf20	236	25	such	such	JJ
cord-016871-1mlamf20	236	26	as	as	IN
cord-016871-1mlamf20	236	27	human	human	JJ
cord-016871-1mlamf20	236	28	immunode	immunode	NNP
cord-016871-1mlamf20	236	29	fi	fi	NNP
cord-016871-1mlamf20	236	30	ciency	ciency	NNP
cord-016871-1mlamf20	236	31	virus	virus	NN
cord-016871-1mlamf20	236	32	(	(	-LRB-
cord-016871-1mlamf20	236	33	HIV	HIV	NNP
cord-016871-1mlamf20	236	34	)	)	-RRB-
cord-016871-1mlamf20	236	35	and	and	CC
cord-016871-1mlamf20	236	36	West	West	NNP
cord-016871-1mlamf20	236	37	Nile	Nile	NNP
cord-016871-1mlamf20	236	38	virus	virus	NN
cord-016871-1mlamf20	236	39	.	.	.
cord-016871-1mlamf20	237	1	Another	another	DT
cord-016871-1mlamf20	237	2	obstacle	obstacle	NN
cord-016871-1mlamf20	237	3	in	in	IN
cord-016871-1mlamf20	237	4	prevention	prevention	NN
cord-016871-1mlamf20	237	5	is	be	VBZ
cord-016871-1mlamf20	237	6	the	the	DT
cord-016871-1mlamf20	237	7	incubation	incubation	NN
cord-016871-1mlamf20	237	8	period	period	NN
cord-016871-1mlamf20	237	9	of	of	IN
cord-016871-1mlamf20	237	10	pathogens	pathogen	NNS
cord-016871-1mlamf20	237	11	before	before	IN
cord-016871-1mlamf20	237	12	seroconversion	seroconversion	NN
cord-016871-1mlamf20	237	13	of	of	IN
cord-016871-1mlamf20	237	14	blood	blood	NN
cord-016871-1mlamf20	237	15	[	[	-LRB-
cord-016871-1mlamf20	237	16	29	29	CD
cord-016871-1mlamf20	237	17	]	]	-RRB-
cord-016871-1mlamf20	237	18	.	.	.
cord-016871-1mlamf20	238	1	Prion	prion	NN
cord-016871-1mlamf20	238	2	diseases	disease	NNS
cord-016871-1mlamf20	238	3	transmitted	transmit	VBN
cord-016871-1mlamf20	238	4	by	by	IN
cord-016871-1mlamf20	238	5	transfusion	transfusion	NN
cord-016871-1mlamf20	238	6	has	have	VBZ
cord-016871-1mlamf20	238	7	been	be	VBN
cord-016871-1mlamf20	238	8	a	a	DT
cord-016871-1mlamf20	238	9	concern	concern	NN
cord-016871-1mlamf20	238	10	in	in	IN
cord-016871-1mlamf20	238	11	the	the	DT
cord-016871-1mlamf20	238	12	UK	UK	NNP
cord-016871-1mlamf20	238	13	,	,	,
cord-016871-1mlamf20	238	14	following	follow	VBG
cord-016871-1mlamf20	238	15	the	the	DT
cord-016871-1mlamf20	238	16	bovine	bovine	JJ
cord-016871-1mlamf20	238	17	spongiform	spongiform	JJ
cord-016871-1mlamf20	238	18	encephalopathy	encephalopathy	NN
cord-016871-1mlamf20	238	19	(	(	-LRB-
cord-016871-1mlamf20	238	20	BSE	BSE	NNP
cord-016871-1mlamf20	238	21	)	)	-RRB-
cord-016871-1mlamf20	238	22	epidemic	epidemic	NN
cord-016871-1mlamf20	238	23	.	.	.
cord-016871-1mlamf20	239	1	Unfortunately	unfortunately	RB
cord-016871-1mlamf20	239	2	,	,	,
cord-016871-1mlamf20	239	3	no	no	DT
cord-016871-1mlamf20	239	4	screening	screening	NN
cord-016871-1mlamf20	239	5	test	test	NN
cord-016871-1mlamf20	239	6	for	for	IN
cord-016871-1mlamf20	239	7	this	this	DT
cord-016871-1mlamf20	239	8	condition	condition	NN
cord-016871-1mlamf20	239	9	has	have	VBZ
cord-016871-1mlamf20	239	10	been	be	VBN
cord-016871-1mlamf20	239	11	established	establish	VBN
cord-016871-1mlamf20	239	12	,	,	,
cord-016871-1mlamf20	239	13	and	and	CC
cord-016871-1mlamf20	239	14	the	the	DT
cord-016871-1mlamf20	239	15	occurrence	occurrence	NN
cord-016871-1mlamf20	239	16	of	of	IN
cord-016871-1mlamf20	239	17	prion	prion	NN
cord-016871-1mlamf20	239	18	diseases	disease	NNS
cord-016871-1mlamf20	239	19	in	in	IN
cord-016871-1mlamf20	239	20	blood	blood	NN
cord-016871-1mlamf20	239	21	products	product	NNS
cord-016871-1mlamf20	239	22	in	in	IN
cord-016871-1mlamf20	239	23	the	the	DT
cord-016871-1mlamf20	239	24	UK	UK	NNP
cord-016871-1mlamf20	239	25	is	be	VBZ
cord-016871-1mlamf20	239	26	largely	largely	RB
cord-016871-1mlamf20	239	27	unknown	unknown	JJ
cord-016871-1mlamf20	239	28	.	.	.
cord-016871-1mlamf20	240	1	In	in	IN
cord-016871-1mlamf20	240	2	order	order	NN
cord-016871-1mlamf20	240	3	to	to	TO
cord-016871-1mlamf20	240	4	avoid	avoid	VB
cord-016871-1mlamf20	240	5	transfusions	transfusion	NNS
cord-016871-1mlamf20	240	6	with	with	IN
cord-016871-1mlamf20	240	7	prion	prion	NN
cord-016871-1mlamf20	240	8	disease	disease	NN
cord-016871-1mlamf20	240	9	,	,	,
cord-016871-1mlamf20	240	10	plasma	plasma	NN
cord-016871-1mlamf20	240	11	has	have	VBZ
cord-016871-1mlamf20	240	12	been	be	VBN
cord-016871-1mlamf20	240	13	imported	import	VBN
cord-016871-1mlamf20	240	14	from	from	IN
cord-016871-1mlamf20	240	15	the	the	DT
cord-016871-1mlamf20	240	16	USA	USA	NNP
cord-016871-1mlamf20	240	17	since	since	IN
cord-016871-1mlamf20	240	18	2002	2002	CD
cord-016871-1mlamf20	240	19	for	for	IN
cord-016871-1mlamf20	240	20	pediatric	pediatric	JJ
cord-016871-1mlamf20	240	21	transfusions	transfusion	NNS
cord-016871-1mlamf20	240	22	[	[	-LRB-
cord-016871-1mlamf20	240	23	35	35	CD
cord-016871-1mlamf20	240	24	]	]	-RRB-
cord-016871-1mlamf20	240	25	.	.	.
cord-016871-1mlamf20	241	1	Another	another	DT
cord-016871-1mlamf20	241	2	concerning	concern	VBG
cord-016871-1mlamf20	241	3	complication	complication	NN
cord-016871-1mlamf20	241	4	is	be	VBZ
cord-016871-1mlamf20	241	5	the	the	DT
cord-016871-1mlamf20	241	6	loss	loss	NN
cord-016871-1mlamf20	241	7	of	of	IN
cord-016871-1mlamf20	241	8	ef	ef	NNP
cord-016871-1mlamf20	241	9	fi	fi	NN
cord-016871-1mlamf20	241	10	cacy	cacy	NN
cord-016871-1mlamf20	241	11	in	in	IN
cord-016871-1mlamf20	241	12	stored	store	VBN
cord-016871-1mlamf20	241	13	blood	blood	NN
cord-016871-1mlamf20	241	14	,	,	,
cord-016871-1mlamf20	241	15	and	and	CC
cord-016871-1mlamf20	241	16	the	the	DT
cord-016871-1mlamf20	241	17	adverse	adverse	JJ
cord-016871-1mlamf20	241	18	effects	effect	NNS
cord-016871-1mlamf20	241	19	it	-PRON-	PRP
cord-016871-1mlamf20	241	20	causes	cause	VBZ
cord-016871-1mlamf20	241	21	.	.	.
cord-016871-1mlamf20	242	1	These	these	DT
cord-016871-1mlamf20	242	2	consequences	consequence	NNS
cord-016871-1mlamf20	242	3	of	of	IN
cord-016871-1mlamf20	242	4	the	the	DT
cord-016871-1mlamf20	242	5	storage	storage	NN
cord-016871-1mlamf20	242	6	process	process	NN
cord-016871-1mlamf20	242	7	are	be	VBP
cord-016871-1mlamf20	242	8	known	know	VBN
cord-016871-1mlamf20	242	9	as	as	IN
cord-016871-1mlamf20	242	10	a	a	DT
cord-016871-1mlamf20	242	11	storage	storage	NN
cord-016871-1mlamf20	242	12	lesion	lesion	NN
cord-016871-1mlamf20	242	13	.	.	.
cord-016871-1mlamf20	243	1	With	with	IN
cord-016871-1mlamf20	243	2	current	current	JJ
cord-016871-1mlamf20	243	3	technology	technology	NN
cord-016871-1mlamf20	243	4	,	,	,
cord-016871-1mlamf20	243	5	the	the	DT
cord-016871-1mlamf20	243	6	shelf	shelf	NN
cord-016871-1mlamf20	243	7	life	life	NN
cord-016871-1mlamf20	243	8	of	of	IN
cord-016871-1mlamf20	243	9	red	red	JJ
cord-016871-1mlamf20	243	10	blood	blood	NN
cord-016871-1mlamf20	243	11	cells	cell	NNS
cord-016871-1mlamf20	243	12	can	can	MD
cord-016871-1mlamf20	243	13	not	not	RB
cord-016871-1mlamf20	243	14	be	be	VB
cord-016871-1mlamf20	243	15	extended	extend	VBN
cord-016871-1mlamf20	243	16	further	far	RBR
cord-016871-1mlamf20	243	17	than	than	IN
cord-016871-1mlamf20	243	18	its	-PRON-	PRP$
cord-016871-1mlamf20	243	19	physiological	physiological	JJ
cord-016871-1mlamf20	243	20	shelf	shelf	NN
cord-016871-1mlamf20	243	21	life	life	NN
cord-016871-1mlamf20	243	22	of	of	IN
cord-016871-1mlamf20	243	23	120	120	CD
cord-016871-1mlamf20	243	24	days	day	NNS
cord-016871-1mlamf20	243	25	,	,	,
cord-016871-1mlamf20	243	26	and	and	CC
cord-016871-1mlamf20	243	27	35	35	CD
cord-016871-1mlamf20	243	28	and	and	CC
cord-016871-1mlamf20	243	29	42	42	CD
cord-016871-1mlamf20	243	30	days	day	NNS
cord-016871-1mlamf20	243	31	is	be	VBZ
cord-016871-1mlamf20	243	32	the	the	DT
cord-016871-1mlamf20	243	33	limit	limit	NN
cord-016871-1mlamf20	243	34	of	of	IN
cord-016871-1mlamf20	243	35	viability	viability	NN
cord-016871-1mlamf20	243	36	in	in	IN
cord-016871-1mlamf20	243	37	whole	whole	JJ
cord-016871-1mlamf20	243	38	blood	blood	NN
cord-016871-1mlamf20	243	39	and	and	CC
cord-016871-1mlamf20	243	40	adenine	adenine	NN
cord-016871-1mlamf20	243	41	-	-	HYPH
cord-016871-1mlamf20	243	42	saline	saline	NN
cord-016871-1mlamf20	243	43	preservation	preservation	NN
cord-016871-1mlamf20	243	44	,	,	,
cord-016871-1mlamf20	243	45	respectively	respectively	RB
cord-016871-1mlamf20	243	46	[	[	-LRB-
cord-016871-1mlamf20	243	47	29	29	CD
cord-016871-1mlamf20	243	48	]	]	-RRB-
cord-016871-1mlamf20	243	49	.	.	.
cord-016871-1mlamf20	244	1	Even	even	RB
cord-016871-1mlamf20	244	2	this	this	DT
cord-016871-1mlamf20	244	3	length	length	NN
cord-016871-1mlamf20	244	4	of	of	IN
cord-016871-1mlamf20	244	5	shelf	shelf	NN
cord-016871-1mlamf20	244	6	-	-	HYPH
cord-016871-1mlamf20	244	7	life	life	NN
cord-016871-1mlamf20	244	8	results	result	NNS
cord-016871-1mlamf20	244	9	in	in	IN
cord-016871-1mlamf20	244	10	counterproductive	counterproductive	JJ
cord-016871-1mlamf20	244	11	transfusions	transfusion	NNS
cord-016871-1mlamf20	244	12	.	.	.
cord-016871-1mlamf20	245	1	Speci	Speci	NNP
cord-016871-1mlamf20	245	2	fi	fi	NNP
cord-016871-1mlamf20	245	3	cally	cally	NNP
cord-016871-1mlamf20	245	4	,	,	,
cord-016871-1mlamf20	245	5	RBC	RBC	NNP
cord-016871-1mlamf20	245	6	products	product	NNS
cord-016871-1mlamf20	245	7	older	old	JJR
cord-016871-1mlamf20	245	8	than	than	IN
cord-016871-1mlamf20	245	9	2	2	CD
cord-016871-1mlamf20	245	10	weeks	week	NNS
cord-016871-1mlamf20	245	11	have	have	VBP
cord-016871-1mlamf20	245	12	been	be	VBN
cord-016871-1mlamf20	245	13	shown	show	VBN
cord-016871-1mlamf20	245	14	to	to	TO
cord-016871-1mlamf20	245	15	not	not	RB
cord-016871-1mlamf20	245	16	improve	improve	VB
cord-016871-1mlamf20	245	17	oxygen	oxygen	NN
cord-016871-1mlamf20	245	18	uptake	uptake	NN
cord-016871-1mlamf20	245	19	in	in	IN
cord-016871-1mlamf20	245	20	septic	septic	JJ
cord-016871-1mlamf20	245	21	patients	patient	NNS
cord-016871-1mlamf20	245	22	.	.	.
cord-016871-1mlamf20	246	1	In	in	IN
cord-016871-1mlamf20	246	2	fact	fact	NN
cord-016871-1mlamf20	246	3	,	,	,
cord-016871-1mlamf20	246	4	RBCs	rbc	NNS
cord-016871-1mlamf20	246	5	of	of	IN
cord-016871-1mlamf20	246	6	that	that	DT
cord-016871-1mlamf20	246	7	age	age	NN
cord-016871-1mlamf20	246	8	have	have	VBP
cord-016871-1mlamf20	246	9	been	be	VBN
cord-016871-1mlamf20	246	10	associated	associate	VBN
cord-016871-1mlamf20	246	11	with	with	IN
cord-016871-1mlamf20	246	12	higher	high	JJR
cord-016871-1mlamf20	246	13	mortality	mortality	NN
cord-016871-1mlamf20	246	14	,	,	,
cord-016871-1mlamf20	246	15	increased	increase	VBD
cord-016871-1mlamf20	246	16	adverse	adverse	JJ
cord-016871-1mlamf20	246	17	events	event	NNS
cord-016871-1mlamf20	246	18	,	,	,
cord-016871-1mlamf20	246	19	extended	extended	JJ
cord-016871-1mlamf20	246	20	hospital	hospital	NN
cord-016871-1mlamf20	246	21	stay	stay	NN
cord-016871-1mlamf20	246	22	,	,	,
cord-016871-1mlamf20	246	23	and	and	CC
cord-016871-1mlamf20	246	24	electrolyte	electrolyte	JJ
cord-016871-1mlamf20	246	25	imbalances	imbalance	NNS
cord-016871-1mlamf20	246	26	.	.	.
cord-016871-1mlamf20	247	1	This	this	DT
cord-016871-1mlamf20	247	2	reduction	reduction	NN
cord-016871-1mlamf20	247	3	in	in	IN
cord-016871-1mlamf20	247	4	ef	ef	NNP
cord-016871-1mlamf20	247	5	fi	fi	NNP
cord-016871-1mlamf20	247	6	cacy	cacy	NN
cord-016871-1mlamf20	247	7	may	may	MD
cord-016871-1mlamf20	247	8	be	be	VB
cord-016871-1mlamf20	247	9	due	due	JJ
cord-016871-1mlamf20	247	10	to	to	IN
cord-016871-1mlamf20	247	11	decreased	decrease	VBN
cord-016871-1mlamf20	247	12	ability	ability	NN
cord-016871-1mlamf20	247	13	of	of	IN
cord-016871-1mlamf20	247	14	the	the	DT
cord-016871-1mlamf20	247	15	older	old	JJR
cord-016871-1mlamf20	247	16	RBCs	rbc	NNS
cord-016871-1mlamf20	247	17	to	to	TO
cord-016871-1mlamf20	247	18	unload	unload	VB
cord-016871-1mlamf20	247	19	oxygen	oxygen	NN
cord-016871-1mlamf20	247	20	[	[	-LRB-
cord-016871-1mlamf20	247	21	29	29	CD
cord-016871-1mlamf20	247	22	]	]	-RRB-
cord-016871-1mlamf20	247	23	.	.	.
cord-016871-1mlamf20	248	1	Another	another	DT
cord-016871-1mlamf20	248	2	proposed	propose	VBN
cord-016871-1mlamf20	248	3	mechanism	mechanism	NN
cord-016871-1mlamf20	248	4	is	be	VBZ
cord-016871-1mlamf20	248	5	that	that	IN
cord-016871-1mlamf20	248	6	since	since	IN
cord-016871-1mlamf20	248	7	stored	store	VBN
cord-016871-1mlamf20	248	8	RBCs	rbc	NNS
cord-016871-1mlamf20	248	9	have	have	VBP
cord-016871-1mlamf20	248	10	depleted	deplete	VBN
cord-016871-1mlamf20	248	11	nitric	nitric	JJ
cord-016871-1mlamf20	248	12	oxide	oxide	NN
cord-016871-1mlamf20	248	13	,	,	,
cord-016871-1mlamf20	248	14	this	this	DT
cord-016871-1mlamf20	248	15	may	may	MD
cord-016871-1mlamf20	248	16	have	have	VB
cord-016871-1mlamf20	248	17	a	a	DT
cord-016871-1mlamf20	248	18	vasoconstrictive	vasoconstrictive	JJ
cord-016871-1mlamf20	248	19	effect	effect	NN
cord-016871-1mlamf20	248	20	,	,	,
cord-016871-1mlamf20	248	21	leading	lead	VBG
cord-016871-1mlamf20	248	22	to	to	IN
cord-016871-1mlamf20	248	23	thrombosis	thrombosis	NN
cord-016871-1mlamf20	248	24	and	and	CC
cord-016871-1mlamf20	248	25	the	the	DT
cord-016871-1mlamf20	248	26	observed	observed	JJ
cord-016871-1mlamf20	248	27	increases	increase	NNS
cord-016871-1mlamf20	248	28	in	in	IN
cord-016871-1mlamf20	248	29	venous	venous	JJ
cord-016871-1mlamf20	248	30	and	and	CC
cord-016871-1mlamf20	248	31	arterial	arterial	JJ
cord-016871-1mlamf20	248	32	thrombotic	thrombotic	JJ
cord-016871-1mlamf20	248	33	events	event	NNS
cord-016871-1mlamf20	248	34	in	in	IN
cord-016871-1mlamf20	248	35	patients	patient	NNS
cord-016871-1mlamf20	248	36	with	with	IN
cord-016871-1mlamf20	248	37	increased	increase	VBN
cord-016871-1mlamf20	248	38	pRBC	prbc	JJ
cord-016871-1mlamf20	248	39	and	and	CC
cord-016871-1mlamf20	248	40	platelet	platelet	NN
cord-016871-1mlamf20	248	41	transfusions	transfusion	NNS
cord-016871-1mlamf20	248	42	[	[	-LRB-
cord-016871-1mlamf20	248	43	42	42	CD
cord-016871-1mlamf20	248	44	]	]	-RRB-
cord-016871-1mlamf20	248	45	.	.	.
cord-016871-1mlamf20	249	1	The	the	DT
cord-016871-1mlamf20	249	2	question	question	NN
cord-016871-1mlamf20	249	3	is	be	VBZ
cord-016871-1mlamf20	249	4	how	how	WRB
cord-016871-1mlamf20	249	5	realistic	realistic	JJ
cord-016871-1mlamf20	249	6	it	-PRON-	PRP
cord-016871-1mlamf20	249	7	is	be	VBZ
cord-016871-1mlamf20	249	8	to	to	TO
cord-016871-1mlamf20	249	9	maintain	maintain	VB
cord-016871-1mlamf20	249	10	strict	strict	JJ
cord-016871-1mlamf20	249	11	storage	storage	NN
cord-016871-1mlamf20	249	12	age	age	NN
cord-016871-1mlamf20	249	13	in	in	IN
cord-016871-1mlamf20	249	14	a	a	DT
cord-016871-1mlamf20	249	15	fi	fi	NN
cord-016871-1mlamf20	249	16	nite	nite	NN
cord-016871-1mlamf20	249	17	and	and	CC
cord-016871-1mlamf20	249	18	scarce	scarce	JJ
cord-016871-1mlamf20	249	19	resource	resource	NN
cord-016871-1mlamf20	249	20	such	such	JJ
cord-016871-1mlamf20	249	21	as	as	IN
cord-016871-1mlamf20	249	22	blood	blood	NN
cord-016871-1mlamf20	249	23	.	.	.
cord-016871-1mlamf20	250	1	A	a	DT
cord-016871-1mlamf20	250	2	doubleblind	doubleblind	NN
cord-016871-1mlamf20	250	3	,	,	,
cord-016871-1mlamf20	250	4	prospective	prospective	JJ
cord-016871-1mlamf20	250	5	randomized	randomized	JJ
cord-016871-1mlamf20	250	6	pilot	pilot	NN
cord-016871-1mlamf20	250	7	study	study	NN
cord-016871-1mlamf20	250	8	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	250	9	that	that	IN
cord-016871-1mlamf20	250	10	controlling	control	VBG
cord-016871-1mlamf20	250	11	the	the	DT
cord-016871-1mlamf20	250	12	storage	storage	NN
cord-016871-1mlamf20	250	13	age	age	NN
cord-016871-1mlamf20	250	14	of	of	IN
cord-016871-1mlamf20	250	15	RBCs	rbc	NNS
cord-016871-1mlamf20	250	16	in	in	IN
cord-016871-1mlamf20	250	17	transfusion	transfusion	NN
cord-016871-1mlamf20	250	18	compared	compare	VBN
cord-016871-1mlamf20	250	19	to	to	IN
cord-016871-1mlamf20	250	20	the	the	DT
cord-016871-1mlamf20	250	21	current	current	JJ
cord-016871-1mlamf20	250	22	standard	standard	NN
cord-016871-1mlamf20	250	23	of	of	IN
cord-016871-1mlamf20	250	24	care	care	NN
cord-016871-1mlamf20	250	25	is	be	VBZ
cord-016871-1mlamf20	250	26	feasible	feasible	JJ
cord-016871-1mlamf20	250	27	and	and	CC
cord-016871-1mlamf20	250	28	results	result	NNS
cord-016871-1mlamf20	250	29	in	in	IN
cord-016871-1mlamf20	250	30	decreased	decrease	VBN
cord-016871-1mlamf20	250	31	exposure	exposure	NN
cord-016871-1mlamf20	250	32	to	to	IN
cord-016871-1mlamf20	250	33	older	old	JJR
cord-016871-1mlamf20	250	34	blood	blood	NN
cord-016871-1mlamf20	250	35	[	[	-LRB-
cord-016871-1mlamf20	250	36	47	47	CD
cord-016871-1mlamf20	250	37	]	]	-RRB-
cord-016871-1mlamf20	250	38	.	.	.
cord-016871-1mlamf20	251	1	More	More	JJR
cord-016871-1mlamf20	251	2	evidence	evidence	NN
cord-016871-1mlamf20	251	3	is	be	VBZ
cord-016871-1mlamf20	251	4	needed	need	VBN
cord-016871-1mlamf20	251	5	to	to	TO
cord-016871-1mlamf20	251	6	determine	determine	VB
cord-016871-1mlamf20	251	7	precisely	precisely	RB
cord-016871-1mlamf20	251	8	the	the	DT
cord-016871-1mlamf20	251	9	cut	cut	NN
cord-016871-1mlamf20	251	10	off	off	RP
cord-016871-1mlamf20	251	11	age	age	NN
cord-016871-1mlamf20	251	12	of	of	IN
cord-016871-1mlamf20	251	13	RBCs	rbc	NNS
cord-016871-1mlamf20	251	14	in	in	IN
cord-016871-1mlamf20	251	15	their	-PRON-	PRP$
cord-016871-1mlamf20	251	16	ef	ef	NN
cord-016871-1mlamf20	251	17	fi	fi	NN
cord-016871-1mlamf20	251	18	cacy	cacy	NN
cord-016871-1mlamf20	251	19	and	and	CC
cord-016871-1mlamf20	251	20	availability	availability	NN
cord-016871-1mlamf20	251	21	.	.	.
cord-016871-1mlamf20	252	1	In	in	IN
cord-016871-1mlamf20	252	2	stored	stored	JJ
cord-016871-1mlamf20	252	3	platelets	platelet	NNS
cord-016871-1mlamf20	252	4	,	,	,
cord-016871-1mlamf20	252	5	it	-PRON-	PRP
cord-016871-1mlamf20	252	6	has	have	VBZ
cord-016871-1mlamf20	252	7	been	be	VBN
cord-016871-1mlamf20	252	8	estimated	estimate	VBN
cord-016871-1mlamf20	252	9	that	that	IN
cord-016871-1mlamf20	252	10	the	the	DT
cord-016871-1mlamf20	252	11	recovery	recovery	NN
cord-016871-1mlamf20	252	12	rate	rate	NN
cord-016871-1mlamf20	252	13	of	of	IN
cord-016871-1mlamf20	252	14	5-day	5-day	JJ
cord-016871-1mlamf20	252	15	old	old	JJ
cord-016871-1mlamf20	252	16	platelets	platelet	NNS
cord-016871-1mlamf20	252	17	is	be	VBZ
cord-016871-1mlamf20	252	18	about	about	RB
cord-016871-1mlamf20	252	19	50	50	CD
cord-016871-1mlamf20	252	20	%	%	NN
cord-016871-1mlamf20	252	21	,	,	,
cord-016871-1mlamf20	252	22	with	with	IN
cord-016871-1mlamf20	252	23	many	many	JJ
cord-016871-1mlamf20	252	24	nonviable	nonviable	JJ
cord-016871-1mlamf20	252	25	platelets	platelet	NNS
cord-016871-1mlamf20	252	26	being	be	VBG
cord-016871-1mlamf20	252	27	sequestered	sequester	VBN
cord-016871-1mlamf20	252	28	into	into	IN
cord-016871-1mlamf20	252	29	the	the	DT
cord-016871-1mlamf20	252	30	spleen	spleen	NN
cord-016871-1mlamf20	252	31	[	[	-LRB-
cord-016871-1mlamf20	252	32	21	21	CD
cord-016871-1mlamf20	252	33	]	]	-RRB-
cord-016871-1mlamf20	252	34	.	.	.
cord-016871-1mlamf20	253	1	For	for	IN
cord-016871-1mlamf20	253	2	these	these	DT
cord-016871-1mlamf20	253	3	reasons	reason	NNS
cord-016871-1mlamf20	253	4	,	,	,
cord-016871-1mlamf20	253	5	there	there	EX
cord-016871-1mlamf20	253	6	is	be	VBZ
cord-016871-1mlamf20	253	7	some	some	DT
cord-016871-1mlamf20	253	8	concern	concern	NN
cord-016871-1mlamf20	253	9	that	that	IN
cord-016871-1mlamf20	253	10	platelet	platelet	NN
cord-016871-1mlamf20	253	11	counts	count	NNS
cord-016871-1mlamf20	253	12	performed	perform	VBN
cord-016871-1mlamf20	253	13	immediately	immediately	RB
cord-016871-1mlamf20	253	14	after	after	IN
cord-016871-1mlamf20	253	15	transfusion	transfusion	NN
cord-016871-1mlamf20	253	16	do	do	VBP
cord-016871-1mlamf20	253	17	not	not	RB
cord-016871-1mlamf20	253	18	provide	provide	VB
cord-016871-1mlamf20	253	19	an	an	DT
cord-016871-1mlamf20	253	20	accurate	accurate	JJ
cord-016871-1mlamf20	253	21	picture	picture	NN
cord-016871-1mlamf20	253	22	of	of	IN
cord-016871-1mlamf20	253	23	platelet	platelet	NN
cord-016871-1mlamf20	253	24	function	function	NN
cord-016871-1mlamf20	253	25	[	[	-LRB-
cord-016871-1mlamf20	253	26	21	21	CD
cord-016871-1mlamf20	253	27	]	]	-RRB-
cord-016871-1mlamf20	253	28	.	.	.
cord-016871-1mlamf20	254	1	Given	give	VBN
cord-016871-1mlamf20	254	2	the	the	DT
cord-016871-1mlamf20	254	3	complications	complication	NNS
cord-016871-1mlamf20	254	4	listed	list	VBN
cord-016871-1mlamf20	254	5	previously	previously	RB
cord-016871-1mlamf20	254	6	,	,	,
cord-016871-1mlamf20	254	7	a	a	DT
cord-016871-1mlamf20	254	8	discussion	discussion	NN
cord-016871-1mlamf20	254	9	of	of	IN
cord-016871-1mlamf20	254	10	known	know	VBN
cord-016871-1mlamf20	254	11	preventative	preventative	JJ
cord-016871-1mlamf20	254	12	measures	measure	NNS
cord-016871-1mlamf20	254	13	is	be	VBZ
cord-016871-1mlamf20	254	14	warranted	warrant	VBN
cord-016871-1mlamf20	254	15	.	.	.
cord-016871-1mlamf20	255	1	Transfusion	transfusion	NN
cord-016871-1mlamf20	255	2	with	with	IN
cord-016871-1mlamf20	255	3	RBCs	rbc	NNS
cord-016871-1mlamf20	255	4	that	that	WDT
cord-016871-1mlamf20	255	5	have	have	VBP
cord-016871-1mlamf20	255	6	not	not	RB
cord-016871-1mlamf20	255	7	been	be	VBN
cord-016871-1mlamf20	255	8	leukoreduced	leukoreduce	VBN
cord-016871-1mlamf20	255	9	has	have	VBZ
cord-016871-1mlamf20	255	10	been	be	VBN
cord-016871-1mlamf20	255	11	associated	associate	VBN
cord-016871-1mlamf20	255	12	with	with	IN
cord-016871-1mlamf20	255	13	increased	increase	VBN
cord-016871-1mlamf20	255	14	risk	risk	NN
cord-016871-1mlamf20	255	15	of	of	IN
cord-016871-1mlamf20	255	16	multiple	multiple	JJ
cord-016871-1mlamf20	255	17	organ	organ	NN
cord-016871-1mlamf20	255	18	failure	failure	NN
cord-016871-1mlamf20	255	19	and	and	CC
cord-016871-1mlamf20	255	20	degenerating	degenerate	VBG
cord-016871-1mlamf20	255	21	leukocytes	leukocyte	NNS
cord-016871-1mlamf20	255	22	may	may	MD
cord-016871-1mlamf20	255	23	cause	cause	VB
cord-016871-1mlamf20	255	24	RBC	RBC	NNP
cord-016871-1mlamf20	255	25	toxicity	toxicity	NN
cord-016871-1mlamf20	255	26	.	.	.
cord-016871-1mlamf20	256	1	Furthermore	furthermore	RB
cord-016871-1mlamf20	256	2	,	,	,
cord-016871-1mlamf20	256	3	nationwide	nationwide	JJ
cord-016871-1mlamf20	256	4	leukoreduction	leukoreduction	NN
cord-016871-1mlamf20	256	5	protocols	protocol	NNS
cord-016871-1mlamf20	256	6	in	in	IN
cord-016871-1mlamf20	256	7	Canada	Canada	NNP
cord-016871-1mlamf20	256	8	were	be	VBD
cord-016871-1mlamf20	256	9	shown	show	VBN
cord-016871-1mlamf20	256	10	to	to	IN
cord-016871-1mlamf20	256	11	lower	low	JJR
cord-016871-1mlamf20	256	12	mortality	mortality	NN
cord-016871-1mlamf20	256	13	rates	rate	NNS
cord-016871-1mlamf20	256	14	[	[	-LRB-
cord-016871-1mlamf20	256	15	29	29	CD
cord-016871-1mlamf20	256	16	]	]	-RRB-
cord-016871-1mlamf20	256	17	.	.	.
cord-016871-1mlamf20	257	1	Currently	currently	RB
cord-016871-1mlamf20	257	2	,	,	,
cord-016871-1mlamf20	257	3	in	in	IN
cord-016871-1mlamf20	257	4	the	the	DT
cord-016871-1mlamf20	257	5	USA	USA	NNP
cord-016871-1mlamf20	257	6	,	,	,
cord-016871-1mlamf20	257	7	leukoreduction	leukoreduction	NN
cord-016871-1mlamf20	257	8	is	be	VBZ
cord-016871-1mlamf20	257	9	not	not	RB
cord-016871-1mlamf20	257	10	a	a	DT
cord-016871-1mlamf20	257	11	standard	standard	JJ
cord-016871-1mlamf20	257	12	practice	practice	NN
cord-016871-1mlamf20	257	13	despite	despite	IN
cord-016871-1mlamf20	257	14	evidence	evidence	NN
cord-016871-1mlamf20	257	15	of	of	IN
cord-016871-1mlamf20	257	16	bene	bene	NNP
cord-016871-1mlamf20	257	17	fi	fi	NNP
cord-016871-1mlamf20	257	18	t	t	NN
cord-016871-1mlamf20	257	19	,	,	,
cord-016871-1mlamf20	257	20	and	and	CC
cord-016871-1mlamf20	257	21	additional	additional	JJ
cord-016871-1mlamf20	257	22	work	work	NN
cord-016871-1mlamf20	257	23	is	be	VBZ
cord-016871-1mlamf20	257	24	required	require	VBN
cord-016871-1mlamf20	257	25	to	to	TO
cord-016871-1mlamf20	257	26	determine	determine	VB
cord-016871-1mlamf20	257	27	effects	effect	NNS
cord-016871-1mlamf20	257	28	on	on	IN
cord-016871-1mlamf20	257	29	outcome	outcome	NN
cord-016871-1mlamf20	257	30	in	in	IN
cord-016871-1mlamf20	257	31	various	various	JJ
cord-016871-1mlamf20	257	32	patient	patient	JJ
cord-016871-1mlamf20	257	33	populations	population	NNS
cord-016871-1mlamf20	257	34	,	,	,
cord-016871-1mlamf20	257	35	such	such	JJ
cord-016871-1mlamf20	257	36	as	as	IN
cord-016871-1mlamf20	257	37	ICU	ICU	NNP
cord-016871-1mlamf20	257	38	patients	patient	NNS
cord-016871-1mlamf20	257	39	[	[	-LRB-
cord-016871-1mlamf20	257	40	29	29	CD
cord-016871-1mlamf20	257	41	]	]	-RRB-
cord-016871-1mlamf20	257	42	.	.	.
cord-016871-1mlamf20	258	1	Hospitalized	hospitalize	VBN
cord-016871-1mlamf20	258	2	patients	patient	NNS
cord-016871-1mlamf20	258	3	receiving	receive	VBG
cord-016871-1mlamf20	258	4	transfusions	transfusion	NNS
cord-016871-1mlamf20	258	5	are	be	VBP
cord-016871-1mlamf20	258	6	already	already	RB
cord-016871-1mlamf20	258	7	in	in	IN
cord-016871-1mlamf20	258	8	a	a	DT
cord-016871-1mlamf20	258	9	vulnerable	vulnerable	JJ
cord-016871-1mlamf20	258	10	state	state	NN
cord-016871-1mlamf20	258	11	of	of	IN
cord-016871-1mlamf20	258	12	health	health	NN
cord-016871-1mlamf20	258	13	,	,	,
cord-016871-1mlamf20	258	14	and	and	CC
cord-016871-1mlamf20	258	15	when	when	WRB
cord-016871-1mlamf20	258	16	transfusion	transfusion	NN
cord-016871-1mlamf20	258	17	-	-	HYPH
cord-016871-1mlamf20	258	18	related	relate	VBN
cord-016871-1mlamf20	258	19	adverse	adverse	JJ
cord-016871-1mlamf20	258	20	events	event	NNS
cord-016871-1mlamf20	258	21	occur	occur	VBP
cord-016871-1mlamf20	258	22	,	,	,
cord-016871-1mlamf20	258	23	it	-PRON-	PRP
cord-016871-1mlamf20	258	24	is	be	VBZ
cord-016871-1mlamf20	258	25	most	most	RBS
cord-016871-1mlamf20	258	26	regrettable	regrettable	JJ
cord-016871-1mlamf20	258	27	.	.	.
cord-016871-1mlamf20	259	1	With	with	IN
cord-016871-1mlamf20	259	2	institutional	institutional	JJ
cord-016871-1mlamf20	259	3	triage	triage	NN
cord-016871-1mlamf20	259	4	protocols	protocol	NNS
cord-016871-1mlamf20	259	5	and	and	CC
cord-016871-1mlamf20	259	6	transfusion	transfusion	NN
cord-016871-1mlamf20	259	7	guidelines	guideline	NNS
cord-016871-1mlamf20	259	8	,	,	,
cord-016871-1mlamf20	259	9	such	such	JJ
cord-016871-1mlamf20	259	10	unnecessary	unnecessary	JJ
cord-016871-1mlamf20	259	11	harm	harm	NN
cord-016871-1mlamf20	259	12	can	can	MD
cord-016871-1mlamf20	259	13	be	be	VB
cord-016871-1mlamf20	259	14	avoided	avoid	VBN
cord-016871-1mlamf20	259	15	,	,	,
cord-016871-1mlamf20	259	16	and	and	CC
cord-016871-1mlamf20	259	17	cost	cost	VBP
cord-016871-1mlamf20	259	18	reduction	reduction	NN
cord-016871-1mlamf20	259	19	of	of	IN
cord-016871-1mlamf20	259	20	a	a	DT
cord-016871-1mlamf20	259	21	limited	limited	JJ
cord-016871-1mlamf20	259	22	and	and	CC
cord-016871-1mlamf20	259	23	precious	precious	JJ
cord-016871-1mlamf20	259	24	resource	resource	NN
cord-016871-1mlamf20	259	25	can	can	MD
cord-016871-1mlamf20	259	26	be	be	VB
cord-016871-1mlamf20	259	27	achieved	achieve	VBN
cord-016871-1mlamf20	259	28	[	[	-LRB-
cord-016871-1mlamf20	259	29	48	48	CD
cord-016871-1mlamf20	259	30	]	]	-RRB-
cord-016871-1mlamf20	259	31	.	.	.
cord-016871-1mlamf20	260	1	Protocols	protocol	NNS
cord-016871-1mlamf20	260	2	and	and	CC
cord-016871-1mlamf20	260	3	scoring	score	VBG
cord-016871-1mlamf20	260	4	systems	system	NNS
cord-016871-1mlamf20	260	5	,	,	,
cord-016871-1mlamf20	260	6	such	such	JJ
cord-016871-1mlamf20	260	7	as	as	IN
cord-016871-1mlamf20	260	8	the	the	DT
cord-016871-1mlamf20	260	9	Emergency	Emergency	NNP
cord-016871-1mlamf20	260	10	Transfusion	Transfusion	NNP
cord-016871-1mlamf20	260	11	Score	Score	NNP
cord-016871-1mlamf20	260	12	(	(	-LRB-
cord-016871-1mlamf20	260	13	ETS	ETS	NNP
cord-016871-1mlamf20	260	14	)	)	-RRB-
cord-016871-1mlamf20	260	15	,	,	,
cord-016871-1mlamf20	260	16	have	have	VBP
cord-016871-1mlamf20	260	17	been	be	VBN
cord-016871-1mlamf20	260	18	successfully	successfully	RB
cord-016871-1mlamf20	260	19	shown	show	VBN
cord-016871-1mlamf20	260	20	to	to	IN
cord-016871-1mlamf20	260	21	triage	triage	NN
cord-016871-1mlamf20	260	22	patients	patient	NNS
cord-016871-1mlamf20	260	23	in	in	IN
cord-016871-1mlamf20	260	24	need	need	NN
cord-016871-1mlamf20	260	25	of	of	IN
cord-016871-1mlamf20	260	26	transfusions	transfusion	NNS
cord-016871-1mlamf20	260	27	and	and	CC
cord-016871-1mlamf20	260	28	those	those	DT
cord-016871-1mlamf20	260	29	for	for	IN
cord-016871-1mlamf20	260	30	whom	whom	WP
cord-016871-1mlamf20	260	31	it	-PRON-	PRP
cord-016871-1mlamf20	260	32	would	would	MD
cord-016871-1mlamf20	260	33	be	be	VB
cord-016871-1mlamf20	260	34	unnecessary	unnecessary	JJ
cord-016871-1mlamf20	260	35	[	[	-LRB-
cord-016871-1mlamf20	260	36	49	49	CD
cord-016871-1mlamf20	260	37	]	]	-RRB-
cord-016871-1mlamf20	260	38	.	.	.
cord-016871-1mlamf20	261	1	There	there	EX
cord-016871-1mlamf20	261	2	are	be	VBP
cord-016871-1mlamf20	261	3	many	many	JJ
cord-016871-1mlamf20	261	4	considerations	consideration	NNS
cord-016871-1mlamf20	261	5	to	to	TO
cord-016871-1mlamf20	261	6	address	address	VB
cord-016871-1mlamf20	261	7	in	in	IN
cord-016871-1mlamf20	261	8	the	the	DT
cord-016871-1mlamf20	261	9	management	management	NN
cord-016871-1mlamf20	261	10	of	of	IN
cord-016871-1mlamf20	261	11	an	an	DT
cord-016871-1mlamf20	261	12	anticoagulated	anticoagulated	JJ
cord-016871-1mlamf20	261	13	surgical	surgical	JJ
cord-016871-1mlamf20	261	14	patient	patient	NN
cord-016871-1mlamf20	261	15	,	,	,
cord-016871-1mlamf20	261	16	such	such	JJ
cord-016871-1mlamf20	261	17	as	as	IN
cord-016871-1mlamf20	261	18	reversing	reverse	VBG
cord-016871-1mlamf20	261	19	anticoagulation	anticoagulation	NN
cord-016871-1mlamf20	261	20	fully	fully	RB
cord-016871-1mlamf20	261	21	before	before	IN
cord-016871-1mlamf20	261	22	operation	operation	NN
cord-016871-1mlamf20	261	23	,	,	,
cord-016871-1mlamf20	261	24	in	in	IN
cord-016871-1mlamf20	261	25	order	order	NN
cord-016871-1mlamf20	261	26	to	to	TO
cord-016871-1mlamf20	261	27	avoid	avoid	VB
cord-016871-1mlamf20	261	28	bleeding	bleed	VBG
cord-016871-1mlamf20	261	29	complications	complication	NNS
cord-016871-1mlamf20	261	30	.	.	.
cord-016871-1mlamf20	262	1	In	in	IN
cord-016871-1mlamf20	262	2	the	the	DT
cord-016871-1mlamf20	262	3	nonelective	nonelective	NN
cord-016871-1mlamf20	262	4	setting	setting	NN
cord-016871-1mlamf20	262	5	,	,	,
cord-016871-1mlamf20	262	6	such	such	JJ
cord-016871-1mlamf20	262	7	as	as	IN
cord-016871-1mlamf20	262	8	life	life	NN
cord-016871-1mlamf20	262	9	-	-	HYPH
cord-016871-1mlamf20	262	10	threatening	threaten	VBG
cord-016871-1mlamf20	262	11	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	262	12	or	or	CC
cord-016871-1mlamf20	262	13	emergent	emergent	JJ
cord-016871-1mlamf20	262	14	surgical	surgical	JJ
cord-016871-1mlamf20	262	15	indications	indication	NNS
cord-016871-1mlamf20	262	16	,	,	,
cord-016871-1mlamf20	262	17	this	this	DT
cord-016871-1mlamf20	262	18	process	process	NN
cord-016871-1mlamf20	262	19	must	must	MD
cord-016871-1mlamf20	262	20	be	be	VB
cord-016871-1mlamf20	262	21	sped	speed	VBN
cord-016871-1mlamf20	262	22	up	up	RP
cord-016871-1mlamf20	262	23	,	,	,
cord-016871-1mlamf20	262	24	using	use	VBG
cord-016871-1mlamf20	262	25	prothrombin	prothrombin	NN
cord-016871-1mlamf20	262	26	complex	complex	NN
cord-016871-1mlamf20	262	27	concentrate	concentrate	NN
cord-016871-1mlamf20	262	28	(	(	-LRB-
cord-016871-1mlamf20	262	29	PCC	PCC	NNP
cord-016871-1mlamf20	262	30	)	)	-RRB-
cord-016871-1mlamf20	262	31	[	[	-LRB-
cord-016871-1mlamf20	262	32	50	50	CD
cord-016871-1mlamf20	262	33	]	]	-RRB-
cord-016871-1mlamf20	262	34	.	.	.
cord-016871-1mlamf20	263	1	Unlike	unlike	IN
cord-016871-1mlamf20	263	2	FFP	FFP	NNP
cord-016871-1mlamf20	263	3	,	,	,
cord-016871-1mlamf20	263	4	PCC	PCC	NNP
cord-016871-1mlamf20	263	5	can	can	MD
cord-016871-1mlamf20	263	6	be	be	VB
cord-016871-1mlamf20	263	7	administered	administer	VBN
cord-016871-1mlamf20	263	8	without	without	IN
cord-016871-1mlamf20	263	9	the	the	DT
cord-016871-1mlamf20	263	10	need	need	NN
cord-016871-1mlamf20	263	11	for	for	IN
cord-016871-1mlamf20	263	12	cross	cross	NN
cord-016871-1mlamf20	263	13	-	-	JJ
cord-016871-1mlamf20	263	14	matching	matching	JJ
cord-016871-1mlamf20	263	15	or	or	CC
cord-016871-1mlamf20	263	16	thawing	thawing	NN
cord-016871-1mlamf20	263	17	,	,	,
cord-016871-1mlamf20	263	18	has	have	VBZ
cord-016871-1mlamf20	263	19	more	more	RBR
cord-016871-1mlamf20	263	20	predictable	predictable	JJ
cord-016871-1mlamf20	263	21	concentrations	concentration	NNS
cord-016871-1mlamf20	263	22	of	of	IN
cord-016871-1mlamf20	263	23	clotting	clotting	NN
cord-016871-1mlamf20	263	24	factors	factor	NNS
cord-016871-1mlamf20	263	25	,	,	,
cord-016871-1mlamf20	263	26	and	and	CC
cord-016871-1mlamf20	263	27	has	have	VBZ
cord-016871-1mlamf20	263	28	been	be	VBN
cord-016871-1mlamf20	263	29	shown	show	VBN
cord-016871-1mlamf20	263	30	to	to	TO
cord-016871-1mlamf20	263	31	reverse	reverse	VB
cord-016871-1mlamf20	263	32	warfarin	warfarin	NN
cord-016871-1mlamf20	263	33	-	-	HYPH
cord-016871-1mlamf20	263	34	related	relate	VBN
cord-016871-1mlamf20	263	35	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	263	36	.	.	.
cord-016871-1mlamf20	264	1	The	the	DT
cord-016871-1mlamf20	264	2	clotting	clotting	NN
cord-016871-1mlamf20	264	3	factors	factor	NNS
cord-016871-1mlamf20	264	4	are	be	VBP
cord-016871-1mlamf20	264	5	also	also	RB
cord-016871-1mlamf20	264	6	in	in	IN
cord-016871-1mlamf20	264	7	high	high	JJ
cord-016871-1mlamf20	264	8	concentrations	concentration	NNS
cord-016871-1mlamf20	264	9	,	,	,
cord-016871-1mlamf20	264	10	approximately	approximately	RB
cord-016871-1mlamf20	264	11	25	25	CD
cord-016871-1mlamf20	264	12	times	time	NNS
cord-016871-1mlamf20	264	13	that	that	DT
cord-016871-1mlamf20	264	14	of	of	IN
cord-016871-1mlamf20	264	15	plasma	plasma	NN
cord-016871-1mlamf20	264	16	,	,	,
cord-016871-1mlamf20	264	17	decreasing	decrease	VBG
cord-016871-1mlamf20	264	18	the	the	DT
cord-016871-1mlamf20	264	19	volume	volume	NN
cord-016871-1mlamf20	264	20	of	of	IN
cord-016871-1mlamf20	264	21	PCC	PCC	NNP
cord-016871-1mlamf20	264	22	needed	need	VBD
cord-016871-1mlamf20	264	23	.	.	.
cord-016871-1mlamf20	265	1	In	in	IN
cord-016871-1mlamf20	265	2	addition	addition	NN
cord-016871-1mlamf20	265	3	,	,	,
cord-016871-1mlamf20	265	4	the	the	DT
cord-016871-1mlamf20	265	5	INR	INR	NNP
cord-016871-1mlamf20	265	6	is	be	VBZ
cord-016871-1mlamf20	265	7	rapidly	rapidly	RB
cord-016871-1mlamf20	265	8	corrected	correct	VBN
cord-016871-1mlamf20	265	9	,	,	,
cord-016871-1mlamf20	265	10	taking	take	VBG
cord-016871-1mlamf20	265	11	about	about	RB
cord-016871-1mlamf20	265	12	15	15	CD
cord-016871-1mlamf20	265	13	min	min	NN
cord-016871-1mlamf20	265	14	[	[	-LRB-
cord-016871-1mlamf20	265	15	50	50	CD
cord-016871-1mlamf20	265	16	]	]	-RRB-
cord-016871-1mlamf20	265	17	.	.	.
cord-016871-1mlamf20	266	1	Anticoagulated	anticoagulated	JJ
cord-016871-1mlamf20	266	2	patients	patient	NNS
cord-016871-1mlamf20	266	3	and	and	CC
cord-016871-1mlamf20	266	4	patients	patient	NNS
cord-016871-1mlamf20	266	5	using	use	VBG
cord-016871-1mlamf20	266	6	antiplatelet	antiplatelet	JJ
cord-016871-1mlamf20	266	7	agents	agent	NNS
cord-016871-1mlamf20	266	8	are	be	VBP
cord-016871-1mlamf20	266	9	especially	especially	RB
cord-016871-1mlamf20	266	10	vulnerable	vulnerable	JJ
cord-016871-1mlamf20	266	11	to	to	IN
cord-016871-1mlamf20	266	12	coagulopathies	coagulopathie	NNS
cord-016871-1mlamf20	266	13	,	,	,
cord-016871-1mlamf20	266	14	which	which	WDT
cord-016871-1mlamf20	266	15	may	may	MD
cord-016871-1mlamf20	266	16	develop	develop	VB
cord-016871-1mlamf20	266	17	during	during	IN
cord-016871-1mlamf20	266	18	resuscitation	resuscitation	NN
cord-016871-1mlamf20	266	19	.	.	.
cord-016871-1mlamf20	267	1	Kılıç	Kılıç	NNP
cord-016871-1mlamf20	267	2	et	et	NNP
cord-016871-1mlamf20	267	3	al	al	NNP
cord-016871-1mlamf20	267	4	.	.	.
cord-016871-1mlamf20	268	1	's	's	POS
cord-016871-1mlamf20	269	1	fi	fi	NNP
cord-016871-1mlamf20	269	2	ndings	nding	NNS
cord-016871-1mlamf20	269	3	recommend	recommend	VBP
cord-016871-1mlamf20	269	4	using	use	VBG
cord-016871-1mlamf20	269	5	individualized	individualized	JJ
cord-016871-1mlamf20	269	6	treatment	treatment	NN
cord-016871-1mlamf20	269	7	,	,	,
cord-016871-1mlamf20	269	8	providing	provide	VBG
cord-016871-1mlamf20	269	9	the	the	DT
cord-016871-1mlamf20	269	10	de	de	FW
cord-016871-1mlamf20	269	11	fi	fi	NNP
cord-016871-1mlamf20	269	12	cient	cient	NNP
cord-016871-1mlamf20	269	13	blood	blood	NN
cord-016871-1mlamf20	269	14	component	component	NN
cord-016871-1mlamf20	269	15	as	as	IN
cord-016871-1mlamf20	269	16	per	per	IN
cord-016871-1mlamf20	269	17	laboratory	laboratory	NN
cord-016871-1mlamf20	269	18	value	value	NN
cord-016871-1mlamf20	269	19	de	de	FW
cord-016871-1mlamf20	269	20	fi	fi	NNP
cord-016871-1mlamf20	269	21	ciency	ciency	NNP
cord-016871-1mlamf20	269	22	[	[	-LRB-
cord-016871-1mlamf20	269	23	16	16	CD
cord-016871-1mlamf20	269	24	]	]	-RRB-
cord-016871-1mlamf20	269	25	.	.	.
cord-016871-1mlamf20	270	1	In	in	IN
cord-016871-1mlamf20	270	2	addition	addition	NN
cord-016871-1mlamf20	270	3	,	,	,
cord-016871-1mlamf20	270	4	patients	patient	NNS
cord-016871-1mlamf20	270	5	who	who	WP
cord-016871-1mlamf20	270	6	are	be	VBP
cord-016871-1mlamf20	270	7	overly	overly	RB
cord-016871-1mlamf20	270	8	anticoagulated	anticoagulate	VBN
cord-016871-1mlamf20	270	9	with	with	IN
cord-016871-1mlamf20	270	10	warfarin	warfarin	NN
cord-016871-1mlamf20	270	11	may	may	MD
cord-016871-1mlamf20	270	12	also	also	RB
cord-016871-1mlamf20	270	13	be	be	VB
cord-016871-1mlamf20	270	14	treated	treat	VBN
cord-016871-1mlamf20	270	15	with	with	IN
cord-016871-1mlamf20	270	16	PCC	PCC	NNP
cord-016871-1mlamf20	270	17	containing	contain	VBG
cord-016871-1mlamf20	270	18	vitamin	vitamin	NN
cord-016871-1mlamf20	270	19	K	k	NN
cord-016871-1mlamf20	270	20	dependent	dependent	JJ
cord-016871-1mlamf20	270	21	factors	factor	NNS
cord-016871-1mlamf20	270	22	[	[	-LRB-
cord-016871-1mlamf20	270	23	16	16	CD
cord-016871-1mlamf20	270	24	]	]	-RRB-
cord-016871-1mlamf20	270	25	.	.	.
cord-016871-1mlamf20	271	1	Due	due	IN
cord-016871-1mlamf20	271	2	to	to	IN
cord-016871-1mlamf20	271	3	the	the	DT
cord-016871-1mlamf20	271	4	teratogenocity	teratogenocity	NN
cord-016871-1mlamf20	271	5	of	of	IN
cord-016871-1mlamf20	271	6	warfarin	warfarin	NN
cord-016871-1mlamf20	271	7	,	,	,
cord-016871-1mlamf20	271	8	pregnant	pregnant	JJ
cord-016871-1mlamf20	271	9	patients	patient	NNS
cord-016871-1mlamf20	271	10	requiring	require	VBG
cord-016871-1mlamf20	271	11	anticoagulation	anticoagulation	NN
cord-016871-1mlamf20	271	12	receive	receive	VBP
cord-016871-1mlamf20	271	13	heparin	heparin	NN
cord-016871-1mlamf20	271	14	as	as	IN
cord-016871-1mlamf20	271	15	the	the	DT
cord-016871-1mlamf20	271	16	preferred	preferred	JJ
cord-016871-1mlamf20	271	17	drug	drug	NN
cord-016871-1mlamf20	271	18	for	for	IN
cord-016871-1mlamf20	271	19	preventing	prevent	VBG
cord-016871-1mlamf20	271	20	pulmonary	pulmonary	JJ
cord-016871-1mlamf20	271	21	embolism	embolism	NN
cord-016871-1mlamf20	271	22	or	or	CC
cord-016871-1mlamf20	271	23	in	in	IN
cord-016871-1mlamf20	271	24	thromboprophylaxis	thromboprophylaxis	NN
cord-016871-1mlamf20	271	25	in	in	IN
cord-016871-1mlamf20	271	26	atrial	atrial	JJ
cord-016871-1mlamf20	271	27	fi	fi	NN
cord-016871-1mlamf20	271	28	brillation	brillation	NN
cord-016871-1mlamf20	271	29	[	[	-LRB-
cord-016871-1mlamf20	271	30	51	51	CD
cord-016871-1mlamf20	271	31	]	]	-RRB-
cord-016871-1mlamf20	271	32	.	.	.
cord-016871-1mlamf20	272	1	Insertion	insertion	NN
cord-016871-1mlamf20	272	2	of	of	IN
cord-016871-1mlamf20	272	3	a	a	DT
cord-016871-1mlamf20	272	4	venal	venal	JJ
cord-016871-1mlamf20	272	5	caval	caval	NN
cord-016871-1mlamf20	272	6	fi	fi	NNP
cord-016871-1mlamf20	272	7	lter	lter	NNP
cord-016871-1mlamf20	272	8	is	be	VBZ
cord-016871-1mlamf20	272	9	another	another	DT
cord-016871-1mlamf20	272	10	option	option	NN
cord-016871-1mlamf20	272	11	.	.	.
cord-016871-1mlamf20	273	1	In	in	IN
cord-016871-1mlamf20	273	2	the	the	DT
cord-016871-1mlamf20	273	3	surgical	surgical	JJ
cord-016871-1mlamf20	273	4	patient	patient	NN
cord-016871-1mlamf20	273	5	,	,	,
cord-016871-1mlamf20	273	6	it	-PRON-	PRP
cord-016871-1mlamf20	273	7	is	be	VBZ
cord-016871-1mlamf20	273	8	important	important	JJ
cord-016871-1mlamf20	273	9	to	to	TO
cord-016871-1mlamf20	273	10	discontinue	discontinue	VB
cord-016871-1mlamf20	273	11	aspirin	aspirin	NN
cord-016871-1mlamf20	273	12	and	and	CC
cord-016871-1mlamf20	273	13	reversible	reversible	JJ
cord-016871-1mlamf20	273	14	platelet	platelet	NN
cord-016871-1mlamf20	273	15	inhibitors	inhibitor	NNS
cord-016871-1mlamf20	273	16	such	such	JJ
cord-016871-1mlamf20	273	17	as	as	IN
cord-016871-1mlamf20	273	18	clopidogrel	clopidogrel	NNP
cord-016871-1mlamf20	273	19	10	10	CD
cord-016871-1mlamf20	273	20	and	and	CC
cord-016871-1mlamf20	273	21	7	7	CD
cord-016871-1mlamf20	273	22	days	day	NNS
cord-016871-1mlamf20	273	23	respectively	respectively	RB
cord-016871-1mlamf20	273	24	before	before	IN
cord-016871-1mlamf20	273	25	an	an	DT
cord-016871-1mlamf20	273	26	operation	operation	NN
cord-016871-1mlamf20	273	27	to	to	TO
cord-016871-1mlamf20	273	28	avoid	avoid	VB
cord-016871-1mlamf20	273	29	bleeding	bleed	VBG
cord-016871-1mlamf20	273	30	complications	complication	NNS
cord-016871-1mlamf20	273	31	[	[	-LRB-
cord-016871-1mlamf20	273	32	50	50	CD
cord-016871-1mlamf20	273	33	]	]	-RRB-
cord-016871-1mlamf20	273	34	.	.	.
cord-016871-1mlamf20	274	1	However	however	RB
cord-016871-1mlamf20	274	2	,	,	,
cord-016871-1mlamf20	274	3	risks	risk	NNS
cord-016871-1mlamf20	274	4	of	of	IN
cord-016871-1mlamf20	274	5	thrombotic	thrombotic	JJ
cord-016871-1mlamf20	274	6	events	event	NNS
cord-016871-1mlamf20	274	7	in	in	IN
cord-016871-1mlamf20	274	8	discontinuation	discontinuation	NN
cord-016871-1mlamf20	274	9	of	of	IN
cord-016871-1mlamf20	274	10	these	these	DT
cord-016871-1mlamf20	274	11	agents	agent	NNS
cord-016871-1mlamf20	274	12	in	in	IN
cord-016871-1mlamf20	274	13	cardiovascular	cardiovascular	JJ
cord-016871-1mlamf20	274	14	surgeries	surgery	NNS
cord-016871-1mlamf20	274	15	have	have	VBP
cord-016871-1mlamf20	274	16	been	be	VBN
cord-016871-1mlamf20	274	17	noted	note	VBN
cord-016871-1mlamf20	274	18	[	[	-LRB-
cord-016871-1mlamf20	274	19	50	50	CD
cord-016871-1mlamf20	274	20	]	]	-RRB-
cord-016871-1mlamf20	274	21	.	.	.
cord-016871-1mlamf20	275	1	Because	because	IN
cord-016871-1mlamf20	275	2	of	of	IN
cord-016871-1mlamf20	275	3	these	these	DT
cord-016871-1mlamf20	275	4	risks	risk	NNS
cord-016871-1mlamf20	275	5	with	with	IN
cord-016871-1mlamf20	275	6	anticoagulated	anticoagulated	JJ
cord-016871-1mlamf20	275	7	patients	patient	NNS
cord-016871-1mlamf20	275	8	and	and	CC
cord-016871-1mlamf20	275	9	patients	patient	NNS
cord-016871-1mlamf20	275	10	receiving	receive	VBG
cord-016871-1mlamf20	275	11	antiplatelet	antiplatelet	JJ
cord-016871-1mlamf20	275	12	agents	agent	NNS
cord-016871-1mlamf20	275	13	,	,	,
cord-016871-1mlamf20	275	14	it	-PRON-	PRP
cord-016871-1mlamf20	275	15	is	be	VBZ
cord-016871-1mlamf20	275	16	important	important	JJ
cord-016871-1mlamf20	275	17	to	to	TO
cord-016871-1mlamf20	275	18	weigh	weigh	VB
cord-016871-1mlamf20	275	19	the	the	DT
cord-016871-1mlamf20	275	20	bene	bene	NN
cord-016871-1mlamf20	275	21	fi	fi	NN
cord-016871-1mlamf20	275	22	ts	ts	NN
cord-016871-1mlamf20	275	23	of	of	IN
cord-016871-1mlamf20	275	24	the	the	DT
cord-016871-1mlamf20	275	25	surgery	surgery	NN
cord-016871-1mlamf20	275	26	against	against	IN
cord-016871-1mlamf20	275	27	these	these	DT
cord-016871-1mlamf20	275	28	risks	risk	NNS
cord-016871-1mlamf20	275	29	,	,	,
cord-016871-1mlamf20	275	30	among	among	IN
cord-016871-1mlamf20	275	31	others	other	NNS
cord-016871-1mlamf20	275	32	.	.	.
cord-016871-1mlamf20	276	1	Obstetric	obstetric	JJ
cord-016871-1mlamf20	276	2	patients	patient	NNS
cord-016871-1mlamf20	276	3	are	be	VBP
cord-016871-1mlamf20	276	4	one	one	CD
cord-016871-1mlamf20	276	5	subpopulation	subpopulation	NN
cord-016871-1mlamf20	276	6	of	of	IN
cord-016871-1mlamf20	276	7	actively	actively	RB
cord-016871-1mlamf20	276	8	bleeding	bleed	VBG
cord-016871-1mlamf20	276	9	surgical	surgical	JJ
cord-016871-1mlamf20	276	10	patients	patient	NNS
cord-016871-1mlamf20	276	11	that	that	WDT
cord-016871-1mlamf20	276	12	can	can	MD
cord-016871-1mlamf20	276	13	easily	easily	RB
cord-016871-1mlamf20	276	14	confuse	confuse	VB
cord-016871-1mlamf20	276	15	the	the	DT
cord-016871-1mlamf20	276	16	provider	provider	NN
cord-016871-1mlamf20	276	17	.	.	.
cord-016871-1mlamf20	277	1	Their	-PRON-	PRP$
cord-016871-1mlamf20	277	2	generally	generally	RB
cord-016871-1mlamf20	277	3	young	young	JJ
cord-016871-1mlamf20	277	4	age	age	NN
cord-016871-1mlamf20	277	5	may	may	MD
cord-016871-1mlamf20	277	6	lead	lead	VB
cord-016871-1mlamf20	277	7	one	one	PRP
cord-016871-1mlamf20	277	8	to	to	TO
cord-016871-1mlamf20	277	9	dismiss	dismiss	VB
cord-016871-1mlamf20	277	10	some	some	DT
cord-016871-1mlamf20	277	11	vital	vital	JJ
cord-016871-1mlamf20	277	12	sign	sign	NN
cord-016871-1mlamf20	277	13	changes	change	NNS
cord-016871-1mlamf20	277	14	or	or	CC
cord-016871-1mlamf20	277	15	lab	lab	NN
cord-016871-1mlamf20	277	16	values	value	NNS
cord-016871-1mlamf20	277	17	,	,	,
cord-016871-1mlamf20	277	18	while	while	IN
cord-016871-1mlamf20	277	19	alterations	alteration	NNS
cord-016871-1mlamf20	277	20	of	of	IN
cord-016871-1mlamf20	277	21	their	-PRON-	PRP$
cord-016871-1mlamf20	277	22	physiology	physiology	NN
cord-016871-1mlamf20	277	23	in	in	IN
cord-016871-1mlamf20	277	24	response	response	NN
cord-016871-1mlamf20	277	25	to	to	IN
cord-016871-1mlamf20	277	26	pregnancy	pregnancy	NN
cord-016871-1mlamf20	277	27	often	often	RB
cord-016871-1mlamf20	277	28	results	result	VBZ
cord-016871-1mlamf20	277	29	in	in	IN
cord-016871-1mlamf20	277	30	the	the	DT
cord-016871-1mlamf20	277	31	misinterpretation	misinterpretation	NN
cord-016871-1mlamf20	277	32	of	of	IN
cord-016871-1mlamf20	277	33	critical	critical	JJ
cord-016871-1mlamf20	277	34	fi	fi	NN
cord-016871-1mlamf20	277	35	ndings	nding	NNS
cord-016871-1mlamf20	277	36	.	.	.
cord-016871-1mlamf20	278	1	During	during	IN
cord-016871-1mlamf20	278	2	pregnancy	pregnancy	NN
cord-016871-1mlamf20	278	3	,	,	,
cord-016871-1mlamf20	278	4	blood	blood	NN
cord-016871-1mlamf20	278	5	becomes	become	VBZ
cord-016871-1mlamf20	278	6	less	less	RBR
cord-016871-1mlamf20	278	7	viscous	viscous	JJ
cord-016871-1mlamf20	278	8	in	in	IN
cord-016871-1mlamf20	278	9	order	order	NN
cord-016871-1mlamf20	278	10	to	to	TO
cord-016871-1mlamf20	278	11	increase	increase	VB
cord-016871-1mlamf20	278	12	oxygen	oxygen	NN
cord-016871-1mlamf20	278	13	carrying	carrying	NN
cord-016871-1mlamf20	278	14	capacity	capacity	NN
cord-016871-1mlamf20	278	15	while	while	IN
cord-016871-1mlamf20	278	16	minimizing	minimize	VBG
cord-016871-1mlamf20	278	17	increased	increase	VBN
cord-016871-1mlamf20	278	18	cardiac	cardiac	JJ
cord-016871-1mlamf20	278	19	load	load	NN
cord-016871-1mlamf20	278	20	as	as	RB
cord-016871-1mlamf20	278	21	much	much	RB
cord-016871-1mlamf20	278	22	as	as	IN
cord-016871-1mlamf20	278	23	possible	possible	JJ
cord-016871-1mlamf20	278	24	.	.	.
cord-016871-1mlamf20	279	1	Intravascular	Intravascular	NNP
cord-016871-1mlamf20	279	2	volume	volume	NN
cord-016871-1mlamf20	279	3	,	,	,
cord-016871-1mlamf20	279	4	and	and	CC
cord-016871-1mlamf20	279	5	more	more	JJR
cord-016871-1mlamf20	279	6	speci	speci	NNS
cord-016871-1mlamf20	279	7	fi	fi	NN
cord-016871-1mlamf20	279	8	cally	cally	RB
cord-016871-1mlamf20	279	9	,	,	,
cord-016871-1mlamf20	279	10	plasma	plasma	NN
cord-016871-1mlamf20	279	11	volume	volume	NN
cord-016871-1mlamf20	279	12	increases	increase	VBZ
cord-016871-1mlamf20	279	13	proportionately	proportionately	RB
cord-016871-1mlamf20	279	14	more	more	JJR
cord-016871-1mlamf20	279	15	than	than	IN
cord-016871-1mlamf20	279	16	red	red	JJ
cord-016871-1mlamf20	279	17	cell	cell	NN
cord-016871-1mlamf20	279	18	volume	volume	NN
cord-016871-1mlamf20	279	19	,	,	,
cord-016871-1mlamf20	279	20	creating	create	VBG
cord-016871-1mlamf20	279	21	a	a	DT
cord-016871-1mlamf20	279	22	"	"	``
cord-016871-1mlamf20	279	23	physiologic	physiologic	JJ
cord-016871-1mlamf20	279	24	anemia	anemia	NN
cord-016871-1mlamf20	279	25	of	of	IN
cord-016871-1mlamf20	279	26	pregnancy	pregnancy	NN
cord-016871-1mlamf20	279	27	"	"	''
cord-016871-1mlamf20	279	28	[	[	-LRB-
cord-016871-1mlamf20	279	29	51	51	CD
cord-016871-1mlamf20	279	30	]	]	-RRB-
cord-016871-1mlamf20	279	31	.	.	.
cord-016871-1mlamf20	280	1	Fibrinogen	fibrinogen	NN
cord-016871-1mlamf20	280	2	,	,	,
cord-016871-1mlamf20	280	3	von	von	NNP
cord-016871-1mlamf20	280	4	Willebrand	Willebrand	NNP
cord-016871-1mlamf20	280	5	factor	factor	NN
cord-016871-1mlamf20	280	6	and	and	CC
cord-016871-1mlamf20	280	7	factors	factor	NNS
cord-016871-1mlamf20	280	8	VII	VII	NNP
cord-016871-1mlamf20	280	9	,	,	,
cord-016871-1mlamf20	280	10	VIII	VIII	NNP
cord-016871-1mlamf20	280	11	,	,	,
cord-016871-1mlamf20	280	12	IX	IX	NNP
cord-016871-1mlamf20	280	13	,	,	,
cord-016871-1mlamf20	280	14	X	X	NNP
cord-016871-1mlamf20	280	15	,	,	,
cord-016871-1mlamf20	280	16	XII	XII	NNP
cord-016871-1mlamf20	280	17	are	be	VBP
cord-016871-1mlamf20	280	18	synthesized	synthesize	VBN
cord-016871-1mlamf20	280	19	more	more	RBR
cord-016871-1mlamf20	280	20	frequently	frequently	RB
cord-016871-1mlamf20	280	21	while	while	IN
cord-016871-1mlamf20	280	22	levels	level	NNS
cord-016871-1mlamf20	280	23	of	of	IN
cord-016871-1mlamf20	280	24	factors	factor	NNS
cord-016871-1mlamf20	280	25	XI	XI	NNP
cord-016871-1mlamf20	280	26	and	and	CC
cord-016871-1mlamf20	280	27	XIII	XIII	NNP
cord-016871-1mlamf20	280	28	and	and	CC
cord-016871-1mlamf20	280	29	platelets	platelet	NNS
cord-016871-1mlamf20	280	30	decrease	decrease	VBP
cord-016871-1mlamf20	280	31	[	[	-LRB-
cord-016871-1mlamf20	280	32	38	38	CD
cord-016871-1mlamf20	280	33	]	]	-RRB-
cord-016871-1mlamf20	280	34	.	.	.
cord-016871-1mlamf20	281	1	Levels	level	NNS
cord-016871-1mlamf20	281	2	of	of	IN
cord-016871-1mlamf20	281	3	factor	factor	NN
cord-016871-1mlamf20	281	4	II	ii	CD
cord-016871-1mlamf20	281	5	decrease	decrease	NN
cord-016871-1mlamf20	281	6	,	,	,
cord-016871-1mlamf20	281	7	yet	yet	CC
cord-016871-1mlamf20	281	8	interestingly	interestingly	RB
cord-016871-1mlamf20	281	9	,	,	,
cord-016871-1mlamf20	281	10	prothrombin	prothrombin	JJ
cord-016871-1mlamf20	281	11	time	time	NN
cord-016871-1mlamf20	281	12	(	(	-LRB-
cord-016871-1mlamf20	281	13	PT	PT	NNP
cord-016871-1mlamf20	281	14	)	)	-RRB-
cord-016871-1mlamf20	281	15	and	and	CC
cord-016871-1mlamf20	281	16	partial	partial	JJ
cord-016871-1mlamf20	281	17	thromboplastin	thromboplastin	NNP
cord-016871-1mlamf20	281	18	time	time	NN
cord-016871-1mlamf20	281	19	(	(	-LRB-
cord-016871-1mlamf20	281	20	PTT	PTT	NNP
cord-016871-1mlamf20	281	21	)	)	-RRB-
cord-016871-1mlamf20	281	22	remain	remain	VBP
cord-016871-1mlamf20	281	23	unaffected	unaffected	JJ
cord-016871-1mlamf20	281	24	[	[	-LRB-
cord-016871-1mlamf20	281	25	51	51	CD
cord-016871-1mlamf20	281	26	]	]	-RRB-
cord-016871-1mlamf20	281	27	.	.	.
cord-016871-1mlamf20	282	1	Mechanical	mechanical	JJ
cord-016871-1mlamf20	282	2	obstruction	obstruction	NN
cord-016871-1mlamf20	282	3	of	of	IN
cord-016871-1mlamf20	282	4	the	the	DT
cord-016871-1mlamf20	282	5	uterus	uterus	NN
cord-016871-1mlamf20	282	6	on	on	IN
cord-016871-1mlamf20	282	7	the	the	DT
cord-016871-1mlamf20	282	8	inferior	inferior	JJ
cord-016871-1mlamf20	282	9	vena	vena	FW
cord-016871-1mlamf20	282	10	cava	cava	NN
cord-016871-1mlamf20	282	11	and	and	CC
cord-016871-1mlamf20	282	12	other	other	JJ
cord-016871-1mlamf20	282	13	vessels	vessel	NNS
cord-016871-1mlamf20	282	14	encourage	encourage	VBP
cord-016871-1mlamf20	282	15	stasis	stasis	NN
cord-016871-1mlamf20	282	16	and	and	CC
cord-016871-1mlamf20	282	17	the	the	DT
cord-016871-1mlamf20	282	18	formation	formation	NN
cord-016871-1mlamf20	282	19	of	of	IN
cord-016871-1mlamf20	282	20	thrombi	thrombi	NNP
cord-016871-1mlamf20	282	21	.	.	.
cord-016871-1mlamf20	283	1	The	the	DT
cord-016871-1mlamf20	283	2	summation	summation	NN
cord-016871-1mlamf20	283	3	of	of	IN
cord-016871-1mlamf20	283	4	these	these	DT
cord-016871-1mlamf20	283	5	effects	effect	NNS
cord-016871-1mlamf20	283	6	result	result	VBP
cord-016871-1mlamf20	283	7	in	in	IN
cord-016871-1mlamf20	283	8	a	a	DT
cord-016871-1mlamf20	283	9	net	net	JJ
cord-016871-1mlamf20	283	10	hypercoagulable	hypercoagulable	JJ
cord-016871-1mlamf20	283	11	state	state	NN
cord-016871-1mlamf20	283	12	[	[	-LRB-
cord-016871-1mlamf20	283	13	51	51	CD
cord-016871-1mlamf20	283	14	]	]	-RRB-
cord-016871-1mlamf20	283	15	.	.	.
cord-016871-1mlamf20	284	1	The	the	DT
cord-016871-1mlamf20	284	2	utero	utero	NN
cord-016871-1mlamf20	284	3	-	-	HYPH
cord-016871-1mlamf20	284	4	placental	placental	JJ
cord-016871-1mlamf20	284	5	circulation	circulation	NN
cord-016871-1mlamf20	284	6	has	have	VBZ
cord-016871-1mlamf20	284	7	increased	increase	VBN
cord-016871-1mlamf20	284	8	activity	activity	NN
cord-016871-1mlamf20	284	9	of	of	IN
cord-016871-1mlamf20	284	10	both	both	DT
cord-016871-1mlamf20	284	11	coagulation	coagulation	NN
cord-016871-1mlamf20	284	12	and	and	CC
cord-016871-1mlamf20	284	13	fi	fi	NNP
cord-016871-1mlamf20	284	14	brinolysis	brinolysis	NNP
cord-016871-1mlamf20	284	15	,	,	,
cord-016871-1mlamf20	284	16	contributing	contribute	VBG
cord-016871-1mlamf20	284	17	to	to	IN
cord-016871-1mlamf20	284	18	increased	increase	VBN
cord-016871-1mlamf20	284	19	levels	level	NNS
cord-016871-1mlamf20	284	20	of	of	IN
cord-016871-1mlamf20	284	21	fi	fi	NNP
cord-016871-1mlamf20	284	22	brin	brin	NNP
cord-016871-1mlamf20	284	23	degradation	degradation	NN
cord-016871-1mlamf20	284	24	products	product	NNS
cord-016871-1mlamf20	284	25	such	such	JJ
cord-016871-1mlamf20	284	26	as	as	IN
cord-016871-1mlamf20	284	27	d	d	NNP
cord-016871-1mlamf20	284	28	-dimer	-dimer	VBN
cord-016871-1mlamf20	284	29	,	,	,
cord-016871-1mlamf20	284	30	especially	especially	RB
cord-016871-1mlamf20	284	31	in	in	IN
cord-016871-1mlamf20	284	32	the	the	DT
cord-016871-1mlamf20	284	33	third	third	JJ
cord-016871-1mlamf20	284	34	trimester	trimester	NN
cord-016871-1mlamf20	284	35	[	[	-LRB-
cord-016871-1mlamf20	284	36	38	38	CD
cord-016871-1mlamf20	284	37	]	]	-RRB-
cord-016871-1mlamf20	284	38	.	.	.
cord-016871-1mlamf20	285	1	This	this	DT
cord-016871-1mlamf20	285	2	effect	effect	NN
cord-016871-1mlamf20	285	3	may	may	MD
cord-016871-1mlamf20	285	4	contribute	contribute	VB
cord-016871-1mlamf20	285	5	to	to	IN
cord-016871-1mlamf20	285	6	the	the	DT
cord-016871-1mlamf20	285	7	hemostatic	hemostatic	JJ
cord-016871-1mlamf20	285	8	challenges	challenge	NNS
cord-016871-1mlamf20	285	9	in	in	IN
cord-016871-1mlamf20	285	10	obstetric	obstetric	JJ
cord-016871-1mlamf20	285	11	patients	patient	NNS
cord-016871-1mlamf20	285	12	.	.	.
cord-016871-1mlamf20	286	1	Anti	Anti	NNP
cord-016871-1mlamf20	286	2	fi	fi	NNP
cord-016871-1mlamf20	286	3	brinolytics	brinolytic	NNS
cord-016871-1mlamf20	286	4	such	such	JJ
cord-016871-1mlamf20	286	5	as	as	IN
cord-016871-1mlamf20	286	6	tranexamic	tranexamic	JJ
cord-016871-1mlamf20	286	7	acid	acid	NN
cord-016871-1mlamf20	286	8	and	and	CC
cord-016871-1mlamf20	286	9	aminocaproic	aminocaproic	NN
cord-016871-1mlamf20	286	10	acid	acid	NN
cord-016871-1mlamf20	286	11	can	can	MD
cord-016871-1mlamf20	286	12	be	be	VB
cord-016871-1mlamf20	286	13	used	use	VBN
cord-016871-1mlamf20	286	14	to	to	TO
cord-016871-1mlamf20	286	15	treat	treat	VB
cord-016871-1mlamf20	286	16	hyper	hyper	JJ
cord-016871-1mlamf20	286	17	fi	fi	NN
cord-016871-1mlamf20	286	18	brinolysis	brinolysis	NN
cord-016871-1mlamf20	286	19	.	.	.
cord-016871-1mlamf20	287	1	In	in	IN
cord-016871-1mlamf20	287	2	fact	fact	NN
cord-016871-1mlamf20	287	3	,	,	,
cord-016871-1mlamf20	287	4	tranexamic	tranexamic	JJ
cord-016871-1mlamf20	287	5	acid	acid	NN
cord-016871-1mlamf20	287	6	has	have	VBZ
cord-016871-1mlamf20	287	7	been	be	VBN
cord-016871-1mlamf20	287	8	shown	show	VBN
cord-016871-1mlamf20	287	9	to	to	TO
cord-016871-1mlamf20	287	10	reduce	reduce	VB
cord-016871-1mlamf20	287	11	blood	blood	NN
cord-016871-1mlamf20	287	12	loss	loss	NN
cord-016871-1mlamf20	287	13	after	after	IN
cord-016871-1mlamf20	287	14	elective	elective	JJ
cord-016871-1mlamf20	287	15	caesarean	caesarean	NN
cord-016871-1mlamf20	287	16	section	section	NN
cord-016871-1mlamf20	287	17	and	and	CC
cord-016871-1mlamf20	287	18	vaginal	vaginal	JJ
cord-016871-1mlamf20	287	19	delivery	delivery	NN
cord-016871-1mlamf20	287	20	[	[	-LRB-
cord-016871-1mlamf20	287	21	38	38	CD
cord-016871-1mlamf20	287	22	]	]	-RRB-
cord-016871-1mlamf20	287	23	.	.	.
cord-016871-1mlamf20	288	1	Plasma	plasma	NN
cord-016871-1mlamf20	288	2	and	and	CC
cord-016871-1mlamf20	288	3	cryoprecipitate	cryoprecipitate	NNP
cord-016871-1mlamf20	288	4	contain	contain	VBP
cord-016871-1mlamf20	288	5	fi	fi	NNP
cord-016871-1mlamf20	288	6	brinogen	brinogen	NNP
cord-016871-1mlamf20	288	7	and	and	CC
cord-016871-1mlamf20	288	8	may	may	MD
cord-016871-1mlamf20	288	9	be	be	VB
cord-016871-1mlamf20	288	10	used	use	VBN
cord-016871-1mlamf20	288	11	to	to	TO
cord-016871-1mlamf20	288	12	replenish	replenish	VB
cord-016871-1mlamf20	288	13	fi	fi	NNP
cord-016871-1mlamf20	288	14	brinogen	brinogen	NNP
cord-016871-1mlamf20	288	15	in	in	IN
cord-016871-1mlamf20	288	16	states	state	NNS
cord-016871-1mlamf20	288	17	of	of	IN
cord-016871-1mlamf20	288	18	hypo	hypo	NNP
cord-016871-1mlamf20	288	19	fi	fi	NNP
cord-016871-1mlamf20	288	20	brinogenemia	brinogenemia	NN
cord-016871-1mlamf20	288	21	(	(	-LRB-
cord-016871-1mlamf20	288	22	<	<	NNP
cord-016871-1mlamf20	288	23	180	180	CD
cord-016871-1mlamf20	288	24	mg	mg	NNP
cord-016871-1mlamf20	288	25	/	/	SYM
cord-016871-1mlamf20	288	26	dL	dl	NN
cord-016871-1mlamf20	288	27	)	)	-RRB-
cord-016871-1mlamf20	288	28	.	.	.
cord-016871-1mlamf20	289	1	Post	post	JJ
cord-016871-1mlamf20	289	2	-	-	JJ
cord-016871-1mlamf20	289	3	partum	partum	JJ
cord-016871-1mlamf20	289	4	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	289	5	(	(	-LRB-
cord-016871-1mlamf20	289	6	PPH	pph	NN
cord-016871-1mlamf20	289	7	)	)	-RRB-
cord-016871-1mlamf20	289	8	is	be	VBZ
cord-016871-1mlamf20	289	9	a	a	DT
cord-016871-1mlamf20	289	10	major	major	JJ
cord-016871-1mlamf20	289	11	cause	cause	NN
cord-016871-1mlamf20	289	12	of	of	IN
cord-016871-1mlamf20	289	13	obstetric	obstetric	JJ
cord-016871-1mlamf20	289	14	mortality	mortality	NN
cord-016871-1mlamf20	289	15	that	that	WDT
cord-016871-1mlamf20	289	16	may	may	MD
cord-016871-1mlamf20	289	17	require	require	VB
cord-016871-1mlamf20	289	18	peripartum	peripartum	NN
cord-016871-1mlamf20	289	19	hysterectomy	hysterectomy	NN
cord-016871-1mlamf20	289	20	and	and	CC
cord-016871-1mlamf20	289	21	is	be	VBZ
cord-016871-1mlamf20	289	22	the	the	DT
cord-016871-1mlamf20	289	23	most	most	RBS
cord-016871-1mlamf20	289	24	common	common	JJ
cord-016871-1mlamf20	289	25	cause	cause	NN
cord-016871-1mlamf20	289	26	of	of	IN
cord-016871-1mlamf20	289	27	maternal	maternal	JJ
cord-016871-1mlamf20	289	28	mortality	mortality	NN
cord-016871-1mlamf20	289	29	worldwide	worldwide	RB
cord-016871-1mlamf20	289	30	.	.	.
cord-016871-1mlamf20	290	1	PPH	pph	NN
cord-016871-1mlamf20	290	2	,	,	,
cord-016871-1mlamf20	290	3	in	in	IN
cord-016871-1mlamf20	290	4	general	general	JJ
cord-016871-1mlamf20	290	5	,	,	,
cord-016871-1mlamf20	290	6	is	be	VBZ
cord-016871-1mlamf20	290	7	not	not	RB
cord-016871-1mlamf20	290	8	associated	associate	VBN
cord-016871-1mlamf20	290	9	with	with	IN
cord-016871-1mlamf20	290	10	underlying	underlying	JJ
cord-016871-1mlamf20	290	11	coagulation	coagulation	NN
cord-016871-1mlamf20	290	12	disorders	disorder	NNS
cord-016871-1mlamf20	290	13	but	but	CC
cord-016871-1mlamf20	290	14	rather	rather	RB
cord-016871-1mlamf20	290	15	acute	acute	JJ
cord-016871-1mlamf20	290	16	events	event	NNS
cord-016871-1mlamf20	290	17	related	relate	VBN
cord-016871-1mlamf20	290	18	to	to	IN
cord-016871-1mlamf20	290	19	placenta	placenta	NN
cord-016871-1mlamf20	290	20	abnormalities	abnormality	NNS
cord-016871-1mlamf20	290	21	,	,	,
cord-016871-1mlamf20	290	22	trauma	trauma	NN
cord-016871-1mlamf20	290	23	from	from	IN
cord-016871-1mlamf20	290	24	large	large	JJ
cord-016871-1mlamf20	290	25	births	birth	NNS
cord-016871-1mlamf20	290	26	or	or	CC
cord-016871-1mlamf20	290	27	instrumentation	instrumentation	NN
cord-016871-1mlamf20	290	28	,	,	,
cord-016871-1mlamf20	290	29	or	or	CC
cord-016871-1mlamf20	290	30	uterine	uterine	JJ
cord-016871-1mlamf20	290	31	atony	atony	NN
cord-016871-1mlamf20	290	32	[	[	-LRB-
cord-016871-1mlamf20	290	33	38	38	CD
cord-016871-1mlamf20	290	34	]	]	-RRB-
cord-016871-1mlamf20	290	35	.	.	.
cord-016871-1mlamf20	291	1	In	in	IN
cord-016871-1mlamf20	291	2	addition	addition	NN
cord-016871-1mlamf20	291	3	to	to	IN
cord-016871-1mlamf20	291	4	rapid	rapid	JJ
cord-016871-1mlamf20	291	5	surgical	surgical	JJ
cord-016871-1mlamf20	291	6	intervention	intervention	NN
cord-016871-1mlamf20	291	7	,	,	,
cord-016871-1mlamf20	291	8	hematologic	hematologic	JJ
cord-016871-1mlamf20	291	9	management	management	NN
cord-016871-1mlamf20	291	10	of	of	IN
cord-016871-1mlamf20	291	11	PPH	PPH	NNP
cord-016871-1mlamf20	291	12	includes	include	VBZ
cord-016871-1mlamf20	291	13	rapid	rapid	JJ
cord-016871-1mlamf20	291	14	volume	volume	NN
cord-016871-1mlamf20	291	15	replacement	replacement	NN
cord-016871-1mlamf20	291	16	and	and	CC
cord-016871-1mlamf20	291	17	blood	blood	NN
cord-016871-1mlamf20	291	18	transfusions	transfusion	NNS
cord-016871-1mlamf20	291	19	.	.	.
cord-016871-1mlamf20	292	1	These	these	DT
cord-016871-1mlamf20	292	2	patients	patient	NNS
cord-016871-1mlamf20	292	3	are	be	VBP
cord-016871-1mlamf20	292	4	likely	likely	JJ
cord-016871-1mlamf20	292	5	to	to	TO
cord-016871-1mlamf20	292	6	bene	bene	NNP
cord-016871-1mlamf20	292	7	fi	fi	NNP
cord-016871-1mlamf20	292	8	t	t	NN
cord-016871-1mlamf20	292	9	from	from	IN
cord-016871-1mlamf20	292	10	management	management	NN
cord-016871-1mlamf20	292	11	strategies	strategy	NNS
cord-016871-1mlamf20	292	12	similar	similar	JJ
cord-016871-1mlamf20	292	13	to	to	IN
cord-016871-1mlamf20	292	14	that	that	DT
cord-016871-1mlamf20	292	15	for	for	IN
cord-016871-1mlamf20	292	16	acutely	acutely	RB
cord-016871-1mlamf20	292	17	injured	injure	VBN
cord-016871-1mlamf20	292	18	patients	patient	NNS
cord-016871-1mlamf20	292	19	who	who	WP
cord-016871-1mlamf20	292	20	are	be	VBP
cord-016871-1mlamf20	292	21	in	in	IN
cord-016871-1mlamf20	292	22	shock	shock	NN
cord-016871-1mlamf20	292	23	from	from	IN
cord-016871-1mlamf20	292	24	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	292	25	.	.	.
cord-016871-1mlamf20	293	1	In	in	IN
cord-016871-1mlamf20	293	2	obstetrical	obstetrical	JJ
cord-016871-1mlamf20	293	3	patients	patient	NNS
cord-016871-1mlamf20	293	4	,	,	,
cord-016871-1mlamf20	293	5	rFVIIa	rFVIIa	NNP
cord-016871-1mlamf20	293	6	has	have	VBZ
cord-016871-1mlamf20	293	7	also	also	RB
cord-016871-1mlamf20	293	8	been	be	VBN
cord-016871-1mlamf20	293	9	found	find	VBN
cord-016871-1mlamf20	293	10	to	to	TO
cord-016871-1mlamf20	293	11	control	control	VB
cord-016871-1mlamf20	293	12	and	and	CC
cord-016871-1mlamf20	293	13	decrease	decrease	VB
cord-016871-1mlamf20	293	14	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	293	15	.	.	.
cord-016871-1mlamf20	294	1	Segal	Segal	NNP
cord-016871-1mlamf20	294	2	et	et	NNP
cord-016871-1mlamf20	294	3	al	al	NNP
cord-016871-1mlamf20	294	4	.	.	.
cord-016871-1mlamf20	295	1	's	's	POS
cord-016871-1mlamf20	295	2	observation	observation	NN
cord-016871-1mlamf20	295	3	of	of	IN
cord-016871-1mlamf20	295	4	three	three	CD
cord-016871-1mlamf20	295	5	patients	patient	NNS
cord-016871-1mlamf20	295	6	with	with	IN
cord-016871-1mlamf20	295	7	PPH	pph	NN
cord-016871-1mlamf20	295	8	,	,	,
cord-016871-1mlamf20	295	9	hypovolemic	hypovolemic	JJ
cord-016871-1mlamf20	295	10	shock	shock	NN
cord-016871-1mlamf20	295	11	,	,	,
cord-016871-1mlamf20	295	12	and	and	CC
cord-016871-1mlamf20	295	13	DIC	DIC	NNP
cord-016871-1mlamf20	295	14	who	who	WP
cord-016871-1mlamf20	295	15	received	receive	VBD
cord-016871-1mlamf20	295	16	massive	massive	JJ
cord-016871-1mlamf20	295	17	transfusions	transfusion	NNS
cord-016871-1mlamf20	295	18	suggests	suggest	VBZ
cord-016871-1mlamf20	295	19	that	that	IN
cord-016871-1mlamf20	295	20	rFVIIa	rfviia	NN
cord-016871-1mlamf20	295	21	may	may	MD
cord-016871-1mlamf20	295	22	be	be	VB
cord-016871-1mlamf20	295	23	bene	bene	NNP
cord-016871-1mlamf20	295	24	fi	fi	NN
cord-016871-1mlamf20	295	25	cial	cial	JJ
cord-016871-1mlamf20	295	26	adjunctive	adjunctive	JJ
cord-016871-1mlamf20	295	27	therapy	therapy	NN
cord-016871-1mlamf20	295	28	after	after	IN
cord-016871-1mlamf20	295	29	the	the	DT
cord-016871-1mlamf20	295	30	completion	completion	NN
cord-016871-1mlamf20	295	31	of	of	IN
cord-016871-1mlamf20	295	32	hysterectomy	hysterectomy	NN
cord-016871-1mlamf20	295	33	[	[	-LRB-
cord-016871-1mlamf20	295	34	52	52	CD
cord-016871-1mlamf20	295	35	]	]	-RRB-
cord-016871-1mlamf20	295	36	.	.	.
cord-016871-1mlamf20	296	1	The	the	DT
cord-016871-1mlamf20	296	2	therapeutic	therapeutic	JJ
cord-016871-1mlamf20	296	3	effect	effect	NN
cord-016871-1mlamf20	296	4	of	of	IN
cord-016871-1mlamf20	296	5	rFVIIa	rfviia	NN
cord-016871-1mlamf20	296	6	may	may	MD
cord-016871-1mlamf20	296	7	be	be	VB
cord-016871-1mlamf20	296	8	due	due	JJ
cord-016871-1mlamf20	296	9	to	to	IN
cord-016871-1mlamf20	296	10	its	-PRON-	PRP$
cord-016871-1mlamf20	296	11	binding	binding	NN
cord-016871-1mlamf20	296	12	of	of	IN
cord-016871-1mlamf20	296	13	tissue	tissue	NN
cord-016871-1mlamf20	296	14	factor	factor	NN
cord-016871-1mlamf20	296	15	at	at	IN
cord-016871-1mlamf20	296	16	the	the	DT
cord-016871-1mlamf20	296	17	site	site	NN
cord-016871-1mlamf20	296	18	of	of	IN
cord-016871-1mlamf20	296	19	vessel	vessel	NN
cord-016871-1mlamf20	296	20	injury	injury	NN
cord-016871-1mlamf20	296	21	and	and	CC
cord-016871-1mlamf20	296	22	forming	form	VBG
cord-016871-1mlamf20	296	23	a	a	DT
cord-016871-1mlamf20	296	24	complex	complex	NN
cord-016871-1mlamf20	296	25	,	,	,
cord-016871-1mlamf20	296	26	activating	activate	VBG
cord-016871-1mlamf20	296	27	platelets	platelet	NNS
cord-016871-1mlamf20	296	28	and	and	CC
cord-016871-1mlamf20	296	29	facilitating	facilitate	VBG
cord-016871-1mlamf20	296	30	fi	fi	NNP
cord-016871-1mlamf20	296	31	brin	brin	NNP
cord-016871-1mlamf20	296	32	clot	clot	NN
cord-016871-1mlamf20	296	33	formation	formation	NN
cord-016871-1mlamf20	296	34	[	[	-LRB-
cord-016871-1mlamf20	296	35	52	52	CD
cord-016871-1mlamf20	296	36	]	]	-RRB-
cord-016871-1mlamf20	296	37	.	.	.
cord-016871-1mlamf20	297	1	However	however	RB
cord-016871-1mlamf20	297	2	,	,	,
cord-016871-1mlamf20	297	3	these	these	DT
cord-016871-1mlamf20	297	4	fi	fi	NNP
cord-016871-1mlamf20	297	5	ndings	nding	NNS
cord-016871-1mlamf20	297	6	have	have	VBP
cord-016871-1mlamf20	297	7	not	not	RB
cord-016871-1mlamf20	297	8	been	be	VBN
cord-016871-1mlamf20	297	9	consistent	consistent	JJ
cord-016871-1mlamf20	297	10	in	in	IN
cord-016871-1mlamf20	297	11	the	the	DT
cord-016871-1mlamf20	297	12	current	current	JJ
cord-016871-1mlamf20	297	13	literature	literature	NN
cord-016871-1mlamf20	297	14	,	,	,
cord-016871-1mlamf20	297	15	and	and	CC
cord-016871-1mlamf20	297	16	especially	especially	RB
cord-016871-1mlamf20	297	17	because	because	IN
cord-016871-1mlamf20	297	18	of	of	IN
cord-016871-1mlamf20	297	19	the	the	DT
cord-016871-1mlamf20	297	20	expense	expense	NN
cord-016871-1mlamf20	297	21	of	of	IN
cord-016871-1mlamf20	297	22	rFVIIa	rfviia	NN
cord-016871-1mlamf20	297	23	,	,	,
cord-016871-1mlamf20	297	24	the	the	DT
cord-016871-1mlamf20	297	25	decision	decision	NN
cord-016871-1mlamf20	297	26	to	to	TO
cord-016871-1mlamf20	297	27	administer	administer	VB
cord-016871-1mlamf20	297	28	this	this	DT
cord-016871-1mlamf20	297	29	to	to	IN
cord-016871-1mlamf20	297	30	the	the	DT
cord-016871-1mlamf20	297	31	patient	patient	NN
cord-016871-1mlamf20	297	32	must	must	MD
cord-016871-1mlamf20	297	33	involve	involve	VB
cord-016871-1mlamf20	297	34	a	a	DT
cord-016871-1mlamf20	297	35	thorough	thorough	JJ
cord-016871-1mlamf20	297	36	consideration	consideration	NN
cord-016871-1mlamf20	297	37	of	of	IN
cord-016871-1mlamf20	297	38	the	the	DT
cord-016871-1mlamf20	297	39	bene	bene	NN
cord-016871-1mlamf20	297	40	fi	fi	NN
cord-016871-1mlamf20	297	41	ts	ts	NNP
cord-016871-1mlamf20	297	42	,	,	,
cord-016871-1mlamf20	297	43	if	if	IN
cord-016871-1mlamf20	297	44	any	any	DT
cord-016871-1mlamf20	297	45	[	[	-LRB-
cord-016871-1mlamf20	297	46	38	38	CD
cord-016871-1mlamf20	297	47	]	]	-RRB-
cord-016871-1mlamf20	297	48	.	.	.
cord-016871-1mlamf20	298	1	Intensive	intensive	JJ
cord-016871-1mlamf20	298	2	care	care	NN
cord-016871-1mlamf20	298	3	unit	unit	NN
cord-016871-1mlamf20	298	4	(	(	-LRB-
cord-016871-1mlamf20	298	5	ICU	ICU	NNP
cord-016871-1mlamf20	298	6	)	)	-RRB-
cord-016871-1mlamf20	298	7	patients	patient	NNS
cord-016871-1mlamf20	298	8	are	be	VBP
cord-016871-1mlamf20	298	9	another	another	DT
cord-016871-1mlamf20	298	10	patient	patient	JJ
cord-016871-1mlamf20	298	11	population	population	NN
cord-016871-1mlamf20	298	12	that	that	WDT
cord-016871-1mlamf20	298	13	frequently	frequently	RB
cord-016871-1mlamf20	298	14	receives	receive	VBZ
cord-016871-1mlamf20	298	15	blood	blood	NN
cord-016871-1mlamf20	298	16	transfusions	transfusion	NNS
cord-016871-1mlamf20	298	17	in	in	IN
cord-016871-1mlamf20	298	18	order	order	NN
cord-016871-1mlamf20	298	19	to	to	TO
cord-016871-1mlamf20	298	20	correct	correct	VB
cord-016871-1mlamf20	298	21	their	-PRON-	PRP$
cord-016871-1mlamf20	298	22	anemia	anemia	NN
cord-016871-1mlamf20	298	23	,	,	,
cord-016871-1mlamf20	298	24	which	which	WDT
cord-016871-1mlamf20	298	25	has	have	VBZ
cord-016871-1mlamf20	298	26	been	be	VBN
cord-016871-1mlamf20	298	27	shown	show	VBN
cord-016871-1mlamf20	298	28	by	by	IN
cord-016871-1mlamf20	298	29	a	a	DT
cord-016871-1mlamf20	298	30	large	large	JJ
cord-016871-1mlamf20	298	31	body	body	NN
cord-016871-1mlamf20	298	32	of	of	IN
cord-016871-1mlamf20	298	33	work	work	NN
cord-016871-1mlamf20	298	34	to	to	TO
cord-016871-1mlamf20	298	35	indicate	indicate	VB
cord-016871-1mlamf20	298	36	worse	bad	JJR
cord-016871-1mlamf20	298	37	prognosis	prognosis	NN
cord-016871-1mlamf20	298	38	[	[	-LRB-
cord-016871-1mlamf20	298	39	29	29	CD
cord-016871-1mlamf20	298	40	]	]	-RRB-
cord-016871-1mlamf20	298	41	.	.	.
cord-016871-1mlamf20	299	1	These	these	DT
cord-016871-1mlamf20	299	2	patients	patient	NNS
cord-016871-1mlamf20	299	3	are	be	VBP
cord-016871-1mlamf20	299	4	anemic	anemic	JJ
cord-016871-1mlamf20	299	5	due	due	IN
cord-016871-1mlamf20	299	6	to	to	IN
cord-016871-1mlamf20	299	7	sepsis	sepsis	NN
cord-016871-1mlamf20	299	8	,	,	,
cord-016871-1mlamf20	299	9	occult	occult	JJ
cord-016871-1mlamf20	299	10	blood	blood	NN
cord-016871-1mlamf20	299	11	loss	loss	NN
cord-016871-1mlamf20	299	12	,	,	,
cord-016871-1mlamf20	299	13	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	299	14	,	,	,
cord-016871-1mlamf20	299	15	decreased	decrease	VBD
cord-016871-1mlamf20	299	16	production	production	NN
cord-016871-1mlamf20	299	17	and	and	CC
cord-016871-1mlamf20	299	18	functional	functional	JJ
cord-016871-1mlamf20	299	19	iron	iron	NN
cord-016871-1mlamf20	299	20	de	de	NN
cord-016871-1mlamf20	299	21	fi	fi	NN
cord-016871-1mlamf20	299	22	ciency	ciency	NN
cord-016871-1mlamf20	299	23	.	.	.
cord-016871-1mlamf20	300	1	ICU	ICU	NNP
cord-016871-1mlamf20	300	2	patients	patient	NNS
cord-016871-1mlamf20	300	3	with	with	IN
cord-016871-1mlamf20	300	4	low	low	JJ
cord-016871-1mlamf20	300	5	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	300	6	levels	level	NNS
cord-016871-1mlamf20	300	7	are	be	VBP
cord-016871-1mlamf20	300	8	more	more	RBR
cord-016871-1mlamf20	300	9	likely	likely	JJ
cord-016871-1mlamf20	300	10	to	to	TO
cord-016871-1mlamf20	300	11	suffer	suffer	VB
cord-016871-1mlamf20	300	12	from	from	IN
cord-016871-1mlamf20	300	13	complications	complication	NNS
cord-016871-1mlamf20	300	14	such	such	JJ
cord-016871-1mlamf20	300	15	as	as	IN
cord-016871-1mlamf20	300	16	sepsis	sepsis	NN
cord-016871-1mlamf20	300	17	,	,	,
cord-016871-1mlamf20	300	18	and	and	CC
cord-016871-1mlamf20	300	19	they	-PRON-	PRP
cord-016871-1mlamf20	300	20	are	be	VBP
cord-016871-1mlamf20	300	21	more	more	RBR
cord-016871-1mlamf20	300	22	likely	likely	JJ
cord-016871-1mlamf20	300	23	to	to	TO
cord-016871-1mlamf20	300	24	experience	experience	VB
cord-016871-1mlamf20	300	25	delayed	delay	VBN
cord-016871-1mlamf20	300	26	weaning	weaning	NN
cord-016871-1mlamf20	300	27	from	from	IN
cord-016871-1mlamf20	300	28	ventilator	ventilator	NN
cord-016871-1mlamf20	300	29	support	support	NN
cord-016871-1mlamf20	300	30	.	.	.
cord-016871-1mlamf20	301	1	The	the	DT
cord-016871-1mlamf20	301	2	decision	decision	NN
cord-016871-1mlamf20	301	3	to	to	TO
cord-016871-1mlamf20	301	4	transfuse	transfuse	VB
cord-016871-1mlamf20	301	5	such	such	JJ
cord-016871-1mlamf20	301	6	patients	patient	NNS
cord-016871-1mlamf20	301	7	should	should	MD
cord-016871-1mlamf20	301	8	weigh	weigh	VB
cord-016871-1mlamf20	301	9	the	the	DT
cord-016871-1mlamf20	301	10	bene	bene	NN
cord-016871-1mlamf20	301	11	fi	fi	NN
cord-016871-1mlamf20	301	12	ts	ts	NN
cord-016871-1mlamf20	301	13	and	and	CC
cord-016871-1mlamf20	301	14	the	the	DT
cord-016871-1mlamf20	301	15	risks	risk	NNS
cord-016871-1mlamf20	301	16	of	of	IN
cord-016871-1mlamf20	301	17	blood	blood	NN
cord-016871-1mlamf20	301	18	transfusions	transfusion	NNS
cord-016871-1mlamf20	301	19	,	,	,
cord-016871-1mlamf20	301	20	especially	especially	RB
cord-016871-1mlamf20	301	21	given	give	VBN
cord-016871-1mlamf20	301	22	the	the	DT
cord-016871-1mlamf20	301	23	patients	patient	NNS
cord-016871-1mlamf20	301	24	'	'	POS
cord-016871-1mlamf20	301	25	increased	increase	VBN
cord-016871-1mlamf20	301	26	susceptibility	susceptibility	NN
cord-016871-1mlamf20	301	27	to	to	IN
cord-016871-1mlamf20	301	28	infections	infection	NNS
cord-016871-1mlamf20	301	29	,	,	,
cord-016871-1mlamf20	301	30	iatrogenic	iatrogenic	JJ
cord-016871-1mlamf20	301	31	events	event	NNS
cord-016871-1mlamf20	301	32	and	and	CC
cord-016871-1mlamf20	301	33	increased	increase	VBN
cord-016871-1mlamf20	301	34	metabolic	metabolic	JJ
cord-016871-1mlamf20	301	35	demands	demand	NNS
cord-016871-1mlamf20	301	36	[	[	-LRB-
cord-016871-1mlamf20	301	37	53	53	CD
cord-016871-1mlamf20	301	38	]	]	-RRB-
cord-016871-1mlamf20	301	39	.	.	.
cord-016871-1mlamf20	302	1	Vincent	Vincent	NNP
cord-016871-1mlamf20	302	2	et	et	NNP
cord-016871-1mlamf20	302	3	al	al	NNP
cord-016871-1mlamf20	302	4	.	.	.
cord-016871-1mlamf20	303	1	's	's	POS
cord-016871-1mlamf20	303	2	multicenter	multicenter	JJ
cord-016871-1mlamf20	303	3	prospective	prospective	JJ
cord-016871-1mlamf20	303	4	observational	observational	JJ
cord-016871-1mlamf20	303	5	study	study	NN
cord-016871-1mlamf20	303	6	of	of	IN
cord-016871-1mlamf20	303	7	1,136	1,136	CD
cord-016871-1mlamf20	303	8	patients	patient	NNS
cord-016871-1mlamf20	303	9	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	303	10	that	that	IN
cord-016871-1mlamf20	303	11	ICU	ICU	NNP
cord-016871-1mlamf20	303	12	patients	patient	NNS
cord-016871-1mlamf20	303	13	frequently	frequently	RB
cord-016871-1mlamf20	303	14	received	receive	VBD
cord-016871-1mlamf20	303	15	transfusions	transfusion	NNS
cord-016871-1mlamf20	303	16	,	,	,
cord-016871-1mlamf20	303	17	with	with	IN
cord-016871-1mlamf20	303	18	a	a	DT
cord-016871-1mlamf20	303	19	transfusion	transfusion	NN
cord-016871-1mlamf20	303	20	rate	rate	NN
cord-016871-1mlamf20	303	21	of	of	IN
cord-016871-1mlamf20	303	22	37	37	CD
cord-016871-1mlamf20	303	23	%	%	NN
cord-016871-1mlamf20	303	24	during	during	IN
cord-016871-1mlamf20	303	25	their	-PRON-	PRP$
cord-016871-1mlamf20	303	26	stay	stay	NN
cord-016871-1mlamf20	303	27	.	.	.
cord-016871-1mlamf20	304	1	The	the	DT
cord-016871-1mlamf20	304	2	patients	patient	NNS
cord-016871-1mlamf20	304	3	who	who	WP
cord-016871-1mlamf20	304	4	received	receive	VBD
cord-016871-1mlamf20	304	5	transfusions	transfusion	NNS
cord-016871-1mlamf20	304	6	also	also	RB
cord-016871-1mlamf20	304	7	experienced	experience	VBD
cord-016871-1mlamf20	304	8	a	a	DT
cord-016871-1mlamf20	304	9	higher	high	JJR
cord-016871-1mlamf20	304	10	mortality	mortality	NN
cord-016871-1mlamf20	304	11	rate	rate	NN
cord-016871-1mlamf20	304	12	,	,	,
cord-016871-1mlamf20	304	13	prolonged	prolonged	JJ
cord-016871-1mlamf20	304	14	hospital	hospital	NN
cord-016871-1mlamf20	304	15	stay	stay	NN
cord-016871-1mlamf20	304	16	,	,	,
cord-016871-1mlamf20	304	17	and	and	CC
cord-016871-1mlamf20	304	18	decreased	decrease	VBD
cord-016871-1mlamf20	304	19	organ	organ	NN
cord-016871-1mlamf20	304	20	function	function	NN
cord-016871-1mlamf20	304	21	[	[	-LRB-
cord-016871-1mlamf20	304	22	53	53	CD
cord-016871-1mlamf20	304	23	]	]	-RRB-
cord-016871-1mlamf20	304	24	.	.	.
cord-016871-1mlamf20	305	1	There	there	EX
cord-016871-1mlamf20	305	2	is	be	VBZ
cord-016871-1mlamf20	305	3	also	also	RB
cord-016871-1mlamf20	305	4	evidence	evidence	NN
cord-016871-1mlamf20	305	5	suggestive	suggestive	JJ
cord-016871-1mlamf20	305	6	of	of	IN
cord-016871-1mlamf20	305	7	increased	increase	VBN
cord-016871-1mlamf20	305	8	transfusions	transfusion	NNS
cord-016871-1mlamf20	305	9	in	in	IN
cord-016871-1mlamf20	305	10	patients	patient	NNS
cord-016871-1mlamf20	305	11	with	with	IN
cord-016871-1mlamf20	305	12	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	305	13	levels	level	NNS
cord-016871-1mlamf20	305	14	higher	high	JJR
cord-016871-1mlamf20	305	15	than	than	IN
cord-016871-1mlamf20	305	16	the	the	DT
cord-016871-1mlamf20	305	17	generally	generally	RB
cord-016871-1mlamf20	305	18	accepted	accept	VBN
cord-016871-1mlamf20	305	19	trigger	trigger	NN
cord-016871-1mlamf20	305	20	value	value	NN
cord-016871-1mlamf20	305	21	of	of	IN
cord-016871-1mlamf20	305	22	8	8	CD
cord-016871-1mlamf20	305	23	g	g	NN
cord-016871-1mlamf20	305	24	/	/	SYM
cord-016871-1mlamf20	305	25	dL.	dL.	NNS
cord-016871-1mlamf20	305	26	Speci	Speci	NNP
cord-016871-1mlamf20	305	27	fi	fi	NNP
cord-016871-1mlamf20	305	28	cally	cally	RB
cord-016871-1mlamf20	305	29	,	,	,
cord-016871-1mlamf20	305	30	Vincent	Vincent	NNP
cord-016871-1mlamf20	305	31	et	et	NNP
cord-016871-1mlamf20	305	32	al	al	NNP
cord-016871-1mlamf20	305	33	.	.	.
cord-016871-1mlamf20	306	1	found	find	VBD
cord-016871-1mlamf20	306	2	that	that	IN
cord-016871-1mlamf20	306	3	in	in	IN
cord-016871-1mlamf20	306	4	under	under	IN
cord-016871-1mlamf20	306	5	30	30	CD
cord-016871-1mlamf20	306	6	%	%	NN
cord-016871-1mlamf20	306	7	of	of	IN
cord-016871-1mlamf20	306	8	cases	case	NNS
cord-016871-1mlamf20	306	9	,	,	,
cord-016871-1mlamf20	306	10	patients	patient	NNS
cord-016871-1mlamf20	306	11	with	with	IN
cord-016871-1mlamf20	306	12	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	306	13	levels	level	NNS
cord-016871-1mlamf20	306	14	greater	great	JJR
cord-016871-1mlamf20	306	15	than	than	IN
cord-016871-1mlamf20	306	16	9	9	CD
cord-016871-1mlamf20	306	17	g	g	NN
cord-016871-1mlamf20	306	18	/	/	SYM
cord-016871-1mlamf20	306	19	dL	dl	NN
cord-016871-1mlamf20	306	20	received	receive	VBD
cord-016871-1mlamf20	306	21	blood	blood	NN
cord-016871-1mlamf20	306	22	transfusions	transfusion	NNS
cord-016871-1mlamf20	306	23	[	[	-LRB-
cord-016871-1mlamf20	306	24	53	53	CD
cord-016871-1mlamf20	306	25	]	]	-RRB-
cord-016871-1mlamf20	306	26	.	.	.
cord-016871-1mlamf20	307	1	Hence	hence	RB
cord-016871-1mlamf20	307	2	,	,	,
cord-016871-1mlamf20	307	3	future	future	JJ
cord-016871-1mlamf20	307	4	work	work	NN
cord-016871-1mlamf20	307	5	is	be	VBZ
cord-016871-1mlamf20	307	6	needed	need	VBN
cord-016871-1mlamf20	307	7	to	to	TO
cord-016871-1mlamf20	307	8	recommend	recommend	VB
cord-016871-1mlamf20	307	9	strict	strict	JJ
cord-016871-1mlamf20	307	10	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	307	11	cut	cut	NN
cord-016871-1mlamf20	307	12	offs	off	NNS
cord-016871-1mlamf20	307	13	for	for	IN
cord-016871-1mlamf20	307	14	transfusion	transfusion	NN
cord-016871-1mlamf20	307	15	.	.	.
cord-016871-1mlamf20	308	1	In	in	IN
cord-016871-1mlamf20	308	2	the	the	DT
cord-016871-1mlamf20	308	3	acute	acute	JJ
cord-016871-1mlamf20	308	4	trauma	trauma	NN
cord-016871-1mlamf20	308	5	setting	setting	NN
cord-016871-1mlamf20	308	6	,	,	,
cord-016871-1mlamf20	308	7	conventional	conventional	JJ
cord-016871-1mlamf20	308	8	coagulation	coagulation	NN
cord-016871-1mlamf20	308	9	testing	testing	NN
cord-016871-1mlamf20	308	10	(	(	-LRB-
cord-016871-1mlamf20	308	11	CCT	CCT	NNP
cord-016871-1mlamf20	308	12	)	)	-RRB-
cord-016871-1mlamf20	308	13	,	,	,
cord-016871-1mlamf20	308	14	which	which	WDT
cord-016871-1mlamf20	308	15	consists	consist	VBZ
cord-016871-1mlamf20	308	16	of	of	IN
cord-016871-1mlamf20	308	17	prothrombin	prothrombin	NN
cord-016871-1mlamf20	308	18	time	time	NN
cord-016871-1mlamf20	308	19	,	,	,
cord-016871-1mlamf20	308	20	international	international	JJ
cord-016871-1mlamf20	308	21	normalized	normalized	JJ
cord-016871-1mlamf20	308	22	ratio	ratio	NN
cord-016871-1mlamf20	308	23	(	(	-LRB-
cord-016871-1mlamf20	308	24	INR	INR	NNP
cord-016871-1mlamf20	308	25	)	)	-RRB-
cord-016871-1mlamf20	308	26	,	,	,
cord-016871-1mlamf20	308	27	partial	partial	JJ
cord-016871-1mlamf20	308	28	thromboplastin	thromboplastin	NNP
cord-016871-1mlamf20	308	29	time	time	NN
cord-016871-1mlamf20	308	30	,	,	,
cord-016871-1mlamf20	308	31	and	and	CC
cord-016871-1mlamf20	308	32	platelet	platelet	NN
cord-016871-1mlamf20	308	33	count	count	NN
cord-016871-1mlamf20	308	34	,	,	,
cord-016871-1mlamf20	308	35	is	be	VBZ
cord-016871-1mlamf20	308	36	used	use	VBN
cord-016871-1mlamf20	308	37	to	to	TO
cord-016871-1mlamf20	308	38	assess	assess	VB
cord-016871-1mlamf20	308	39	coagulation	coagulation	NN
cord-016871-1mlamf20	308	40	status	status	NN
cord-016871-1mlamf20	308	41	.	.	.
cord-016871-1mlamf20	309	1	This	this	DT
cord-016871-1mlamf20	309	2	approach	approach	NN
cord-016871-1mlamf20	309	3	,	,	,
cord-016871-1mlamf20	309	4	however	however	RB
cord-016871-1mlamf20	309	5	,	,	,
cord-016871-1mlamf20	309	6	is	be	VBZ
cord-016871-1mlamf20	309	7	limited	limit	VBN
cord-016871-1mlamf20	309	8	by	by	IN
cord-016871-1mlamf20	309	9	slow	slow	JJ
cord-016871-1mlamf20	309	10	results	result	NNS
cord-016871-1mlamf20	309	11	,	,	,
cord-016871-1mlamf20	309	12	incomplete	incomplete	JJ
cord-016871-1mlamf20	309	13	characterization	characterization	NN
cord-016871-1mlamf20	309	14	of	of	IN
cord-016871-1mlamf20	309	15	the	the	DT
cord-016871-1mlamf20	309	16	coagulation	coagulation	NN
cord-016871-1mlamf20	309	17	abnormality	abnormality	NN
cord-016871-1mlamf20	309	18	,	,	,
cord-016871-1mlamf20	309	19	and	and	CC
cord-016871-1mlamf20	309	20	poor	poor	JJ
cord-016871-1mlamf20	309	21	prediction	prediction	NN
cord-016871-1mlamf20	309	22	of	of	IN
cord-016871-1mlamf20	309	23	patient	patient	JJ
cord-016871-1mlamf20	309	24	outcome	outcome	NN
cord-016871-1mlamf20	309	25	.	.	.
cord-016871-1mlamf20	310	1	Furthermore	furthermore	RB
cord-016871-1mlamf20	310	2	,	,	,
cord-016871-1mlamf20	310	3	CCTs	cct	NNS
cord-016871-1mlamf20	310	4	,	,	,
cord-016871-1mlamf20	310	5	which	which	WDT
cord-016871-1mlamf20	310	6	are	be	VBP
cord-016871-1mlamf20	310	7	riddled	riddle	VBN
cord-016871-1mlamf20	310	8	with	with	IN
cord-016871-1mlamf20	310	9	delays	delay	NNS
cord-016871-1mlamf20	310	10	from	from	IN
cord-016871-1mlamf20	310	11	time	time	NN
cord-016871-1mlamf20	310	12	to	to	IN
cord-016871-1mlamf20	310	13	arrival	arrival	NN
cord-016871-1mlamf20	310	14	in	in	IN
cord-016871-1mlamf20	310	15	the	the	DT
cord-016871-1mlamf20	310	16	laboratory	laboratory	NN
cord-016871-1mlamf20	310	17	and	and	CC
cord-016871-1mlamf20	310	18	duration	duration	NN
cord-016871-1mlamf20	310	19	of	of	IN
cord-016871-1mlamf20	310	20	testing	testing	NN
cord-016871-1mlamf20	310	21	,	,	,
cord-016871-1mlamf20	310	22	end	end	VB
cord-016871-1mlamf20	310	23	up	up	RP
cord-016871-1mlamf20	310	24	re	re	VBD
cord-016871-1mlamf20	310	25	fl	fl	NNP
cord-016871-1mlamf20	310	26	ecting	ecte	VBG
cord-016871-1mlamf20	310	27	the	the	DT
cord-016871-1mlamf20	310	28	coagulation	coagulation	NN
cord-016871-1mlamf20	310	29	state	state	NN
cord-016871-1mlamf20	310	30	of	of	IN
cord-016871-1mlamf20	310	31	the	the	DT
cord-016871-1mlamf20	310	32	patient	patient	NN
cord-016871-1mlamf20	310	33	after	after	IN
cord-016871-1mlamf20	310	34	30	30	CD
cord-016871-1mlamf20	310	35	-	-	SYM
cord-016871-1mlamf20	310	36	45	45	CD
cord-016871-1mlamf20	310	37	min	min	NNS
cord-016871-1mlamf20	310	38	of	of	IN
cord-016871-1mlamf20	310	39	interventions	intervention	NNS
cord-016871-1mlamf20	310	40	and	and	CC
cord-016871-1mlamf20	310	41	resuscitation	resuscitation	NN
cord-016871-1mlamf20	310	42	[	[	-LRB-
cord-016871-1mlamf20	310	43	54	54	CD
cord-016871-1mlamf20	310	44	]	]	-RRB-
cord-016871-1mlamf20	310	45	.	.	.
cord-016871-1mlamf20	311	1	Since	since	IN
cord-016871-1mlamf20	311	2	CCT	CCT	NNP
cord-016871-1mlamf20	311	3	only	only	RB
cord-016871-1mlamf20	311	4	examines	examine	VBZ
cord-016871-1mlamf20	311	5	plasma	plasma	NN
cord-016871-1mlamf20	311	6	factors	factor	NNS
cord-016871-1mlamf20	311	7	,	,	,
cord-016871-1mlamf20	311	8	the	the	DT
cord-016871-1mlamf20	311	9	integral	integral	JJ
cord-016871-1mlamf20	311	10	role	role	NN
cord-016871-1mlamf20	311	11	of	of	IN
cord-016871-1mlamf20	311	12	platelets	platelet	NNS
cord-016871-1mlamf20	311	13	and	and	CC
cord-016871-1mlamf20	311	14	their	-PRON-	PRP$
cord-016871-1mlamf20	311	15	function	function	NN
cord-016871-1mlamf20	311	16	is	be	VBZ
cord-016871-1mlamf20	311	17	ignored	ignore	VBN
cord-016871-1mlamf20	311	18	.	.	.
cord-016871-1mlamf20	312	1	In	in	IN
cord-016871-1mlamf20	312	2	addition	addition	NN
cord-016871-1mlamf20	312	3	,	,	,
cord-016871-1mlamf20	312	4	the	the	DT
cord-016871-1mlamf20	312	5	CCT	CCT	NNP
cord-016871-1mlamf20	312	6	assesses	assess	VBZ
cord-016871-1mlamf20	312	7	only	only	RB
cord-016871-1mlamf20	312	8	the	the	DT
cord-016871-1mlamf20	312	9	extrinsic	extrinsic	JJ
cord-016871-1mlamf20	312	10	pathway	pathway	NN
cord-016871-1mlamf20	312	11	,	,	,
cord-016871-1mlamf20	312	12	intrinsic	intrinsic	JJ
cord-016871-1mlamf20	312	13	pathway	pathway	NN
cord-016871-1mlamf20	312	14	,	,	,
cord-016871-1mlamf20	312	15	and	and	CC
cord-016871-1mlamf20	312	16	platelet	platelet	NN
cord-016871-1mlamf20	312	17	count	count	NN
cord-016871-1mlamf20	312	18	,	,	,
cord-016871-1mlamf20	312	19	painting	paint	VBG
cord-016871-1mlamf20	312	20	an	an	DT
cord-016871-1mlamf20	312	21	incomplete	incomplete	JJ
cord-016871-1mlamf20	312	22	picture	picture	NN
cord-016871-1mlamf20	312	23	of	of	IN
cord-016871-1mlamf20	312	24	the	the	DT
cord-016871-1mlamf20	312	25	pathologies	pathology	NNS
cord-016871-1mlamf20	312	26	of	of	IN
cord-016871-1mlamf20	312	27	clotting	clotting	NN
cord-016871-1mlamf20	312	28	in	in	IN
cord-016871-1mlamf20	312	29	the	the	DT
cord-016871-1mlamf20	312	30	severely	severely	RB
cord-016871-1mlamf20	312	31	exsanguinating	exsanguinate	VBG
cord-016871-1mlamf20	312	32	patient	patient	NN
cord-016871-1mlamf20	312	33	.	.	.
cord-016871-1mlamf20	313	1	These	these	DT
cord-016871-1mlamf20	313	2	de	de	FW
cord-016871-1mlamf20	313	3	fi	fi	NNP
cord-016871-1mlamf20	313	4	ciencies	ciencie	NNS
cord-016871-1mlamf20	313	5	are	be	VBP
cord-016871-1mlamf20	313	6	addressed	address	VBN
cord-016871-1mlamf20	313	7	by	by	IN
cord-016871-1mlamf20	313	8	thrombelastography	thrombelastography	NNP
cord-016871-1mlamf20	313	9	(	(	-LRB-
cord-016871-1mlamf20	313	10	TEG	TEG	NNP
cord-016871-1mlamf20	313	11	)	)	-RRB-
cord-016871-1mlamf20	313	12	,	,	,
cord-016871-1mlamf20	313	13	a	a	DT
cord-016871-1mlamf20	313	14	test	test	NN
cord-016871-1mlamf20	313	15	that	that	WDT
cord-016871-1mlamf20	313	16	creates	create	VBZ
cord-016871-1mlamf20	313	17	a	a	DT
cord-016871-1mlamf20	313	18	dynamic	dynamic	JJ
cord-016871-1mlamf20	313	19	,	,	,
cord-016871-1mlamf20	313	20	graphical	graphical	JJ
cord-016871-1mlamf20	313	21	representation	representation	NN
cord-016871-1mlamf20	313	22	of	of	IN
cord-016871-1mlamf20	313	23	the	the	DT
cord-016871-1mlamf20	313	24	coagulation	coagulation	NN
cord-016871-1mlamf20	313	25	characteristics	characteristic	NNS
cord-016871-1mlamf20	313	26	of	of	IN
cord-016871-1mlamf20	313	27	a	a	DT
cord-016871-1mlamf20	313	28	blood	blood	NN
cord-016871-1mlamf20	313	29	sample	sample	NN
cord-016871-1mlamf20	313	30	from	from	IN
cord-016871-1mlamf20	313	31	initial	initial	JJ
cord-016871-1mlamf20	313	32	clot	clot	NN
cord-016871-1mlamf20	313	33	formation	formation	NN
cord-016871-1mlamf20	313	34	to	to	IN
cord-016871-1mlamf20	313	35	fi	fi	NNP
cord-016871-1mlamf20	313	36	brinolysis	brinolysis	NNP
cord-016871-1mlamf20	313	37	.	.	.
cord-016871-1mlamf20	314	1	Since	since	IN
cord-016871-1mlamf20	314	2	speci	speci	NNP
cord-016871-1mlamf20	314	3	fi	fi	NNP
cord-016871-1mlamf20	314	4	c	c	NNP
cord-016871-1mlamf20	314	5	coagulation	coagulation	NN
cord-016871-1mlamf20	314	6	components	component	NNS
cord-016871-1mlamf20	314	7	have	have	VBP
cord-016871-1mlamf20	314	8	speci	speci	NNP
cord-016871-1mlamf20	314	9	fi	fi	NN
cord-016871-1mlamf20	314	10	c	c	NN
cord-016871-1mlamf20	314	11	disturbances	disturbance	NNS
cord-016871-1mlamf20	314	12	on	on	IN
cord-016871-1mlamf20	314	13	TEG	TEG	NNP
cord-016871-1mlamf20	314	14	,	,	,
cord-016871-1mlamf20	314	15	this	this	DT
cord-016871-1mlamf20	314	16	test	test	NN
cord-016871-1mlamf20	314	17	reveals	reveal	VBZ
cord-016871-1mlamf20	314	18	diagnostic	diagnostic	JJ
cord-016871-1mlamf20	314	19	as	as	RB
cord-016871-1mlamf20	314	20	well	well	RB
cord-016871-1mlamf20	314	21	as	as	IN
cord-016871-1mlamf20	314	22	therapeutic	therapeutic	JJ
cord-016871-1mlamf20	314	23	information	information	NN
cord-016871-1mlamf20	314	24	[	[	-LRB-
cord-016871-1mlamf20	314	25	55	55	CD
cord-016871-1mlamf20	314	26	]	]	-RRB-
cord-016871-1mlamf20	314	27	.	.	.
cord-016871-1mlamf20	315	1	The	the	DT
cord-016871-1mlamf20	315	2	procedure	procedure	NN
cord-016871-1mlamf20	315	3	involves	involve	VBZ
cord-016871-1mlamf20	315	4	obtaining	obtain	VBG
cord-016871-1mlamf20	315	5	an	an	DT
cord-016871-1mlamf20	315	6	uncitrated	uncitrated	JJ
cord-016871-1mlamf20	315	7	whole	whole	JJ
cord-016871-1mlamf20	315	8	blood	blood	NN
cord-016871-1mlamf20	315	9	sample	sample	NN
cord-016871-1mlamf20	315	10	,	,	,
cord-016871-1mlamf20	315	11	activation	activation	NN
cord-016871-1mlamf20	315	12	of	of	IN
cord-016871-1mlamf20	315	13	the	the	DT
cord-016871-1mlamf20	315	14	specimen	specimen	NN
cord-016871-1mlamf20	315	15	with	with	IN
cord-016871-1mlamf20	315	16	kaolin	kaolin	NN
cord-016871-1mlamf20	315	17	and	and	CC
cord-016871-1mlamf20	315	18	spinning	spin	VBG
cord-016871-1mlamf20	315	19	the	the	DT
cord-016871-1mlamf20	315	20	sample	sample	NN
cord-016871-1mlamf20	315	21	in	in	IN
cord-016871-1mlamf20	315	22	a	a	DT
cord-016871-1mlamf20	315	23	thrombelastograph	thrombelastograph	JJ
cord-016871-1mlamf20	315	24	machine	machine	NN
cord-016871-1mlamf20	315	25	within	within	IN
cord-016871-1mlamf20	315	26	4	4	CD
cord-016871-1mlamf20	315	27	-	-	SYM
cord-016871-1mlamf20	315	28	5	5	CD
cord-016871-1mlamf20	315	29	min	min	NN
cord-016871-1mlamf20	315	30	in	in	IN
cord-016871-1mlamf20	315	31	order	order	NN
cord-016871-1mlamf20	315	32	to	to	TO
cord-016871-1mlamf20	315	33	avoid	avoid	VB
cord-016871-1mlamf20	315	34	clotting	clot	VBG
cord-016871-1mlamf20	315	35	[	[	-LRB-
cord-016871-1mlamf20	315	36	55	55	CD
cord-016871-1mlamf20	315	37	]	]	-RRB-
cord-016871-1mlamf20	315	38	.	.	.
cord-016871-1mlamf20	316	1	If	if	IN
cord-016871-1mlamf20	316	2	this	this	DT
cord-016871-1mlamf20	316	3	timeframe	timeframe	NN
cord-016871-1mlamf20	316	4	can	can	MD
cord-016871-1mlamf20	316	5	not	not	RB
cord-016871-1mlamf20	316	6	be	be	VB
cord-016871-1mlamf20	316	7	achieved	achieve	VBN
cord-016871-1mlamf20	316	8	,	,	,
cord-016871-1mlamf20	316	9	a	a	DT
cord-016871-1mlamf20	316	10	"	"	``
cord-016871-1mlamf20	316	11	reversal	reversal	NN
cord-016871-1mlamf20	316	12	"	"	''
cord-016871-1mlamf20	316	13	method	method	NN
cord-016871-1mlamf20	316	14	can	can	MD
cord-016871-1mlamf20	316	15	be	be	VB
cord-016871-1mlamf20	316	16	used	use	VBN
cord-016871-1mlamf20	316	17	,	,	,
cord-016871-1mlamf20	316	18	where	where	WRB
cord-016871-1mlamf20	316	19	citrate	citrate	NNP
cord-016871-1mlamf20	316	20	is	be	VBZ
cord-016871-1mlamf20	316	21	used	use	VBN
cord-016871-1mlamf20	316	22	to	to	TO
cord-016871-1mlamf20	316	23	avoid	avoid	VB
cord-016871-1mlamf20	316	24	clotting	clotting	NN
cord-016871-1mlamf20	316	25	until	until	IN
cord-016871-1mlamf20	316	26	the	the	DT
cord-016871-1mlamf20	316	27	sample	sample	NN
cord-016871-1mlamf20	316	28	has	have	VBZ
cord-016871-1mlamf20	316	29	arrived	arrive	VBN
cord-016871-1mlamf20	316	30	at	at	IN
cord-016871-1mlamf20	316	31	the	the	DT
cord-016871-1mlamf20	316	32	laboratory	laboratory	NN
cord-016871-1mlamf20	316	33	,	,	,
cord-016871-1mlamf20	316	34	at	at	IN
cord-016871-1mlamf20	316	35	which	which	WDT
cord-016871-1mlamf20	316	36	point	point	NN
cord-016871-1mlamf20	316	37	,	,	,
cord-016871-1mlamf20	316	38	the	the	DT
cord-016871-1mlamf20	316	39	citrate	citrate	NN
cord-016871-1mlamf20	316	40	will	will	MD
cord-016871-1mlamf20	316	41	be	be	VB
cord-016871-1mlamf20	316	42	"	"	``
cord-016871-1mlamf20	316	43	reversed	reverse	VBN
cord-016871-1mlamf20	316	44	"	"	''
cord-016871-1mlamf20	316	45	using	use	VBG
cord-016871-1mlamf20	316	46	calcium	calcium	NN
cord-016871-1mlamf20	316	47	chloride	chloride	NN
cord-016871-1mlamf20	316	48	as	as	IN
cord-016871-1mlamf20	316	49	per	per	IN
cord-016871-1mlamf20	316	50	manufacturer	manufacturer	NN
cord-016871-1mlamf20	316	51	instructions	instruction	NNS
cord-016871-1mlamf20	316	52	.	.	.
cord-016871-1mlamf20	317	1	While	while	IN
cord-016871-1mlamf20	317	2	this	this	DT
cord-016871-1mlamf20	317	3	method	method	NN
cord-016871-1mlamf20	317	4	has	have	VBZ
cord-016871-1mlamf20	317	5	been	be	VBN
cord-016871-1mlamf20	317	6	shown	show	VBN
cord-016871-1mlamf20	317	7	to	to	TO
cord-016871-1mlamf20	317	8	affect	affect	VB
cord-016871-1mlamf20	317	9	TEG	TEG	NNP
cord-016871-1mlamf20	317	10	results	result	NNS
cord-016871-1mlamf20	317	11	,	,	,
cord-016871-1mlamf20	317	12	it	-PRON-	PRP
cord-016871-1mlamf20	317	13	has	have	VBZ
cord-016871-1mlamf20	317	14	not	not	RB
cord-016871-1mlamf20	317	15	been	be	VBN
cord-016871-1mlamf20	317	16	shown	show	VBN
cord-016871-1mlamf20	317	17	to	to	TO
cord-016871-1mlamf20	317	18	be	be	VB
cord-016871-1mlamf20	317	19	inferior	inferior	JJ
cord-016871-1mlamf20	317	20	to	to	IN
cord-016871-1mlamf20	317	21	the	the	DT
cord-016871-1mlamf20	317	22	standard	standard	JJ
cord-016871-1mlamf20	317	23	method	method	NN
cord-016871-1mlamf20	317	24	and	and	CC
cord-016871-1mlamf20	317	25	may	may	MD
cord-016871-1mlamf20	317	26	be	be	VB
cord-016871-1mlamf20	317	27	used	use	VBN
cord-016871-1mlamf20	317	28	in	in	IN
cord-016871-1mlamf20	317	29	centers	center	NNS
cord-016871-1mlamf20	317	30	where	where	WRB
cord-016871-1mlamf20	317	31	4	4	CD
cord-016871-1mlamf20	317	32	-	-	SYM
cord-016871-1mlamf20	317	33	5	5	CD
cord-016871-1mlamf20	317	34	min	min	NN
cord-016871-1mlamf20	317	35	from	from	IN
cord-016871-1mlamf20	317	36	sample	sample	NN
cord-016871-1mlamf20	317	37	collection	collection	NN
cord-016871-1mlamf20	317	38	to	to	IN
cord-016871-1mlamf20	317	39	running	run	VBG
cord-016871-1mlamf20	317	40	the	the	DT
cord-016871-1mlamf20	317	41	TEG	TEG	NNP
cord-016871-1mlamf20	317	42	is	be	VBZ
cord-016871-1mlamf20	317	43	not	not	RB
cord-016871-1mlamf20	317	44	realistic	realistic	JJ
cord-016871-1mlamf20	317	45	[	[	-LRB-
cord-016871-1mlamf20	317	46	55	55	CD
cord-016871-1mlamf20	317	47	]	]	-RRB-
cord-016871-1mlamf20	317	48	.	.	.
cord-016871-1mlamf20	318	1	Rapid	Rapid	NNP
cord-016871-1mlamf20	318	2	TEG	TEG	NNP
cord-016871-1mlamf20	318	3	differs	differ	VBZ
cord-016871-1mlamf20	318	4	from	from	IN
cord-016871-1mlamf20	318	5	conventional	conventional	JJ
cord-016871-1mlamf20	318	6	TEG	TEG	NNP
cord-016871-1mlamf20	318	7	in	in	IN
cord-016871-1mlamf20	318	8	its	-PRON-	PRP$
cord-016871-1mlamf20	318	9	addition	addition	NN
cord-016871-1mlamf20	318	10	of	of	IN
cord-016871-1mlamf20	318	11	tissue	tissue	NN
cord-016871-1mlamf20	318	12	factor	factor	NN
cord-016871-1mlamf20	318	13	to	to	IN
cord-016871-1mlamf20	318	14	the	the	DT
cord-016871-1mlamf20	318	15	blood	blood	NN
cord-016871-1mlamf20	318	16	sample	sample	NN
cord-016871-1mlamf20	318	17	and	and	CC
cord-016871-1mlamf20	318	18	kaolin	kaolin	NN
cord-016871-1mlamf20	318	19	,	,	,
cord-016871-1mlamf20	318	20	accelerating	accelerate	VBG
cord-016871-1mlamf20	318	21	activation	activation	NN
cord-016871-1mlamf20	318	22	of	of	IN
cord-016871-1mlamf20	318	23	the	the	DT
cord-016871-1mlamf20	318	24	clotting	clotting	NN
cord-016871-1mlamf20	318	25	cascade	cascade	NN
cord-016871-1mlamf20	318	26	.	.	.
cord-016871-1mlamf20	319	1	This	this	DT
cord-016871-1mlamf20	319	2	modi	modi	NNP
cord-016871-1mlamf20	319	3	fi	fi	NN
cord-016871-1mlamf20	319	4	cation	cation	NN
cord-016871-1mlamf20	319	5	makes	make	VBZ
cord-016871-1mlamf20	319	6	it	-PRON-	PRP
cord-016871-1mlamf20	319	7	well	well	RB
cord-016871-1mlamf20	319	8	suited	suited	JJ
cord-016871-1mlamf20	319	9	for	for	IN
cord-016871-1mlamf20	319	10	the	the	DT
cord-016871-1mlamf20	319	11	trauma	trauma	NN
cord-016871-1mlamf20	319	12	setting	set	VBG
cord-016871-1mlamf20	319	13	since	since	IN
cord-016871-1mlamf20	319	14	its	-PRON-	PRP$
cord-016871-1mlamf20	319	15	results	result	NNS
cord-016871-1mlamf20	319	16	are	be	VBP
cord-016871-1mlamf20	319	17	available	available	JJ
cord-016871-1mlamf20	319	18	much	much	RB
cord-016871-1mlamf20	319	19	earlier	early	RBR
cord-016871-1mlamf20	319	20	,	,	,
cord-016871-1mlamf20	319	21	namely	namely	RB
cord-016871-1mlamf20	319	22	under	under	IN
cord-016871-1mlamf20	319	23	20	20	CD
cord-016871-1mlamf20	319	24	min	min	NN
cord-016871-1mlamf20	319	25	,	,	,
cord-016871-1mlamf20	319	26	compared	compare	VBN
cord-016871-1mlamf20	319	27	to	to	IN
cord-016871-1mlamf20	319	28	kaolin	kaolin	NN
cord-016871-1mlamf20	319	29	TEG	TEG	NNP
cord-016871-1mlamf20	319	30	and	and	CC
cord-016871-1mlamf20	319	31	CCTs	CCTs	NNP
cord-016871-1mlamf20	319	32	,	,	,
cord-016871-1mlamf20	319	33	which	which	WDT
cord-016871-1mlamf20	319	34	can	can	MD
cord-016871-1mlamf20	319	35	take	take	VB
cord-016871-1mlamf20	319	36	over	over	RP
cord-016871-1mlamf20	319	37	30	30	CD
cord-016871-1mlamf20	319	38	min	min	NN
cord-016871-1mlamf20	319	39	,	,	,
cord-016871-1mlamf20	319	40	without	without	IN
cord-016871-1mlamf20	319	41	sacri	sacri	NN
cord-016871-1mlamf20	319	42	fi	fi	NN
cord-016871-1mlamf20	319	43	cing	cing	NNP
cord-016871-1mlamf20	319	44	accuracy	accuracy	NN
cord-016871-1mlamf20	319	45	[	[	-LRB-
cord-016871-1mlamf20	319	46	55	55	CD
cord-016871-1mlamf20	319	47	]	]	-RRB-
cord-016871-1mlamf20	319	48	.	.	.
cord-016871-1mlamf20	320	1	Interpreting	interpret	VBG
cord-016871-1mlamf20	320	2	the	the	DT
cord-016871-1mlamf20	320	3	results	result	NNS
cord-016871-1mlamf20	320	4	involves	involve	VBZ
cord-016871-1mlamf20	320	5	analyzing	analyze	VBG
cord-016871-1mlamf20	320	6	each	each	DT
cord-016871-1mlamf20	320	7	of	of	IN
cord-016871-1mlamf20	320	8	the	the	DT
cord-016871-1mlamf20	320	9	sequential	sequential	JJ
cord-016871-1mlamf20	320	10	measurements	measurement	NNS
cord-016871-1mlamf20	320	11	(	(	-LRB-
cord-016871-1mlamf20	320	12	Fig	Fig	NNP
cord-016871-1mlamf20	320	13	.	.	.
cord-016871-1mlamf20	320	14	12	12	CD
cord-016871-1mlamf20	320	15	.	.	CD
cord-016871-1mlamf20	320	16	2	2	CD
cord-016871-1mlamf20	320	17	)	)	-RRB-
cord-016871-1mlamf20	320	18	.	.	.
cord-016871-1mlamf20	321	1	Reaction	reaction	NN
cord-016871-1mlamf20	321	2	time	time	NN
cord-016871-1mlamf20	321	3	,	,	,
cord-016871-1mlamf20	321	4	or	or	CC
cord-016871-1mlamf20	321	5	R	r	NN
cord-016871-1mlamf20	321	6	-	-	HYPH
cord-016871-1mlamf20	321	7	time	time	NN
cord-016871-1mlamf20	321	8	,	,	,
cord-016871-1mlamf20	321	9	in	in	IN
cord-016871-1mlamf20	321	10	TEG	TEG	NNP
cord-016871-1mlamf20	321	11	is	be	VBZ
cord-016871-1mlamf20	321	12	the	the	DT
cord-016871-1mlamf20	321	13	time	time	NN
cord-016871-1mlamf20	321	14	until	until	IN
cord-016871-1mlamf20	321	15	initial	initial	JJ
cord-016871-1mlamf20	321	16	clot	clot	NN
cord-016871-1mlamf20	321	17	formation	formation	NN
cord-016871-1mlamf20	321	18	.	.	.
cord-016871-1mlamf20	322	1	It	-PRON-	PRP
cord-016871-1mlamf20	322	2	is	be	VBZ
cord-016871-1mlamf20	322	3	also	also	RB
cord-016871-1mlamf20	322	4	known	know	VBN
cord-016871-1mlamf20	322	5	as	as	IN
cord-016871-1mlamf20	322	6	activated	activate	VBN
cord-016871-1mlamf20	322	7	clotting	clotting	NN
cord-016871-1mlamf20	322	8	time	time	NN
cord-016871-1mlamf20	322	9	(	(	-LRB-
cord-016871-1mlamf20	322	10	ACT	ACT	NNP
cord-016871-1mlamf20	322	11	)	)	-RRB-
cord-016871-1mlamf20	322	12	in	in	IN
cord-016871-1mlamf20	322	13	r	r	NNP
cord-016871-1mlamf20	322	14	-	-	HYPH
cord-016871-1mlamf20	322	15	TEG	TEG	NNP
cord-016871-1mlamf20	322	16	in	in	IN
cord-016871-1mlamf20	322	17	order	order	NN
cord-016871-1mlamf20	322	18	to	to	TO
cord-016871-1mlamf20	322	19	denote	denote	VB
cord-016871-1mlamf20	322	20	intentional	intentional	JJ
cord-016871-1mlamf20	322	21	anticoagulant	anticoagulant	JJ
cord-016871-1mlamf20	322	22	agents	agent	NNS
cord-016871-1mlamf20	322	23	in	in	IN
cord-016871-1mlamf20	322	24	the	the	DT
cord-016871-1mlamf20	322	25	sample	sample	NN
cord-016871-1mlamf20	322	26	.	.	.
cord-016871-1mlamf20	323	1	Factor	factor	NN
cord-016871-1mlamf20	323	2	de	de	NNP
cord-016871-1mlamf20	323	3	fi	fi	NN
cord-016871-1mlamf20	323	4	ciency	ciency	NN
cord-016871-1mlamf20	323	5	or	or	CC
cord-016871-1mlamf20	323	6	severe	severe	JJ
cord-016871-1mlamf20	323	7	hemodilution	hemodilution	NN
cord-016871-1mlamf20	323	8	can	can	MD
cord-016871-1mlamf20	323	9	prolong	prolong	VB
cord-016871-1mlamf20	323	10	reaction	reaction	NN
cord-016871-1mlamf20	323	11	time	time	NN
cord-016871-1mlamf20	323	12	or	or	CC
cord-016871-1mlamf20	323	13	ACT	act	NN
cord-016871-1mlamf20	323	14	.	.	.
cord-016871-1mlamf20	324	1	Next	next	RB
cord-016871-1mlamf20	324	2	,	,	,
cord-016871-1mlamf20	324	3	k	k	NNP
cord-016871-1mlamf20	324	4	-time	-time	NNP
cord-016871-1mlamf20	324	5	represents	represent	VBZ
cord-016871-1mlamf20	324	6	the	the	DT
cord-016871-1mlamf20	324	7	time	time	NN
cord-016871-1mlamf20	324	8	needed	need	VBN
cord-016871-1mlamf20	324	9	to	to	TO
cord-016871-1mlamf20	324	10	reach	reach	VB
cord-016871-1mlamf20	324	11	20-mm	20-mm	JJ
cord-016871-1mlamf20	324	12	clot	clot	NN
cord-016871-1mlamf20	324	13	strength	strength	NN
cord-016871-1mlamf20	324	14	,	,	,
cord-016871-1mlamf20	324	15	and	and	CC
cord-016871-1mlamf20	324	16	has	have	VBZ
cord-016871-1mlamf20	324	17	a	a	DT
cord-016871-1mlamf20	324	18	normal	normal	JJ
cord-016871-1mlamf20	324	19	range	range	NN
cord-016871-1mlamf20	324	20	of	of	IN
cord-016871-1mlamf20	324	21	1	1	CD
cord-016871-1mlamf20	324	22	-	-	SYM
cord-016871-1mlamf20	324	23	2	2	CD
cord-016871-1mlamf20	324	24	min	min	NN
cord-016871-1mlamf20	324	25	.	.	.
cord-016871-1mlamf20	325	1	The	the	DT
cord-016871-1mlamf20	325	2	-angle	-angle	NN
cord-016871-1mlamf20	325	3	,	,	,
cord-016871-1mlamf20	325	4	normally	normally	RB
cord-016871-1mlamf20	325	5	between	between	IN
cord-016871-1mlamf20	325	6	66	66	CD
cord-016871-1mlamf20	325	7	and	and	CC
cord-016871-1mlamf20	325	8	82	82	CD
cord-016871-1mlamf20	325	9	°	°	NNS
cord-016871-1mlamf20	325	10	,	,	,
cord-016871-1mlamf20	325	11	represents	represent	VBZ
cord-016871-1mlamf20	325	12	the	the	DT
cord-016871-1mlamf20	325	13	rate	rate	NN
cord-016871-1mlamf20	325	14	of	of	IN
cord-016871-1mlamf20	325	15	clot	clot	NN
cord-016871-1mlamf20	325	16	formation	formation	NN
cord-016871-1mlamf20	325	17	.	.	.
cord-016871-1mlamf20	326	1	In	in	IN
cord-016871-1mlamf20	326	2	platelet	platelet	NN
cord-016871-1mlamf20	326	3	de	de	FW
cord-016871-1mlamf20	326	4	fi	fi	FW
cord-016871-1mlamf20	326	5	ciency	ciency	NN
cord-016871-1mlamf20	326	6	or	or	CC
cord-016871-1mlamf20	326	7	hypo	hypo	NN
cord-016871-1mlamf20	326	8	fi	fi	NNP
cord-016871-1mlamf20	326	9	brinogenemia	brinogenemia	NN
cord-016871-1mlamf20	326	10	,	,	,
cord-016871-1mlamf20	326	11	where	where	WRB
cord-016871-1mlamf20	326	12	one	one	CD
cord-016871-1mlamf20	326	13	of	of	IN
cord-016871-1mlamf20	326	14	the	the	DT
cord-016871-1mlamf20	326	15	two	two	CD
cord-016871-1mlamf20	326	16	key	key	JJ
cord-016871-1mlamf20	326	17	components	component	NNS
cord-016871-1mlamf20	326	18	of	of	IN
cord-016871-1mlamf20	326	19	clots	clot	NNS
cord-016871-1mlamf20	326	20	are	be	VBP
cord-016871-1mlamf20	326	21	missing	miss	VBG
cord-016871-1mlamf20	326	22	,	,	,
cord-016871-1mlamf20	326	23	the	the	DT
cord-016871-1mlamf20	326	24	k	k	NNP
cord-016871-1mlamf20	326	25	-time	-time	NNP
cord-016871-1mlamf20	326	26	is	be	VBZ
cord-016871-1mlamf20	326	27	increased	increase	VBN
cord-016871-1mlamf20	326	28	and	and	CC
cord-016871-1mlamf20	326	29	the	the	DT
cord-016871-1mlamf20	326	30	-angle	-angle	NN
cord-016871-1mlamf20	326	31	is	be	VBZ
cord-016871-1mlamf20	326	32	decreased	decrease	VBN
cord-016871-1mlamf20	326	33	.	.	.
cord-016871-1mlamf20	327	1	Oshita	Oshita	NNP
cord-016871-1mlamf20	327	2	et	et	NNP
cord-016871-1mlamf20	327	3	al	al	NNP
cord-016871-1mlamf20	327	4	.	.	NNP
cord-016871-1mlamf20	327	5	's	's	POS
cord-016871-1mlamf20	327	6	linear	linear	JJ
cord-016871-1mlamf20	327	7	regression	regression	NN
cord-016871-1mlamf20	327	8	analysis	analysis	NN
cord-016871-1mlamf20	327	9	of	of	IN
cord-016871-1mlamf20	327	10	36	36	CD
cord-016871-1mlamf20	327	11	samples	sample	NNS
cord-016871-1mlamf20	327	12	from	from	IN
cord-016871-1mlamf20	327	13	healthy	healthy	JJ
cord-016871-1mlamf20	327	14	individuals	individual	NNS
cord-016871-1mlamf20	327	15	reported	report	VBD
cord-016871-1mlamf20	327	16	that	that	IN
cord-016871-1mlamf20	327	17	MA	MA	NNP
cord-016871-1mlamf20	327	18	and	and	CC
cord-016871-1mlamf20	327	19	k	k	NNP
cord-016871-1mlamf20	327	20	-time	-time	NNP
cord-016871-1mlamf20	327	21	were	be	VBD
cord-016871-1mlamf20	327	22	linearly	linearly	RB
cord-016871-1mlamf20	327	23	related	relate	VBN
cord-016871-1mlamf20	327	24	to	to	IN
cord-016871-1mlamf20	327	25	platelet	platelet	NN
cord-016871-1mlamf20	327	26	count	count	NN
cord-016871-1mlamf20	327	27	[	[	-LRB-
cord-016871-1mlamf20	327	28	56	56	CD
cord-016871-1mlamf20	327	29	]	]	-RRB-
cord-016871-1mlamf20	327	30	.	.	.
cord-016871-1mlamf20	328	1	The	the	DT
cord-016871-1mlamf20	328	2	maximal	maximal	JJ
cord-016871-1mlamf20	328	3	amplitude	amplitude	NN
cord-016871-1mlamf20	328	4	(	(	-LRB-
cord-016871-1mlamf20	328	5	MA	MA	NNP
cord-016871-1mlamf20	328	6	)	)	-RRB-
cord-016871-1mlamf20	328	7	of	of	IN
cord-016871-1mlamf20	328	8	the	the	DT
cord-016871-1mlamf20	328	9	tracing	tracing	NN
cord-016871-1mlamf20	328	10	represents	represent	VBZ
cord-016871-1mlamf20	328	11	platelet	platelet	NN
cord-016871-1mlamf20	328	12	contribution	contribution	NN
cord-016871-1mlamf20	328	13	to	to	IN
cord-016871-1mlamf20	328	14	clot	clot	NN
cord-016871-1mlamf20	328	15	strength	strength	NN
cord-016871-1mlamf20	328	16	(	(	-LRB-
cord-016871-1mlamf20	328	17	normal	normal	JJ
cord-016871-1mlamf20	328	18	range	range	NN
cord-016871-1mlamf20	328	19	54	54	CD
cord-016871-1mlamf20	328	20	-	-	SYM
cord-016871-1mlamf20	328	21	72	72	CD
cord-016871-1mlamf20	328	22	mm	mm	NN
cord-016871-1mlamf20	328	23	)	)	-RRB-
cord-016871-1mlamf20	328	24	.	.	.
cord-016871-1mlamf20	329	1	It	-PRON-	PRP
cord-016871-1mlamf20	329	2	is	be	VBZ
cord-016871-1mlamf20	329	3	decreased	decrease	VBN
cord-016871-1mlamf20	329	4	in	in	IN
cord-016871-1mlamf20	329	5	states	state	NNS
cord-016871-1mlamf20	329	6	of	of	IN
cord-016871-1mlamf20	329	7	platelet	platelet	NN
cord-016871-1mlamf20	329	8	dysfunction	dysfunction	NN
cord-016871-1mlamf20	329	9	and	and	CC
cord-016871-1mlamf20	329	10	hypo	hypo	NN
cord-016871-1mlamf20	329	11	fi	fi	NNP
cord-016871-1mlamf20	329	12	brinogenemia	brinogenemia	NN
cord-016871-1mlamf20	329	13	.	.	.
cord-016871-1mlamf20	330	1	The	the	DT
cord-016871-1mlamf20	330	2	G	g	NN
cord-016871-1mlamf20	330	3	-value	-value	NN
cord-016871-1mlamf20	330	4	represents	represent	VBZ
cord-016871-1mlamf20	330	5	overall	overall	JJ
cord-016871-1mlamf20	330	6	clot	clot	NN
cord-016871-1mlamf20	330	7	strength	strength	NN
cord-016871-1mlamf20	330	8	,	,	,
cord-016871-1mlamf20	330	9	including	include	VBG
cord-016871-1mlamf20	330	10	platelet	platelet	NN
cord-016871-1mlamf20	330	11	function	function	NN
cord-016871-1mlamf20	330	12	as	as	RB
cord-016871-1mlamf20	330	13	well	well	RB
cord-016871-1mlamf20	330	14	as	as	IN
cord-016871-1mlamf20	330	15	enzymatic	enzymatic	JJ
cord-016871-1mlamf20	330	16	,	,	,
cord-016871-1mlamf20	330	17	and	and	CC
cord-016871-1mlamf20	330	18	is	be	VBZ
cord-016871-1mlamf20	330	19	decreased	decrease	VBN
cord-016871-1mlamf20	330	20	in	in	IN
cord-016871-1mlamf20	330	21	hypocoagulable	hypocoagulable	NNP
cord-016871-1mlamf20	330	22	states	state	NNS
cord-016871-1mlamf20	330	23	(	(	-LRB-
cord-016871-1mlamf20	330	24	normal	normal	JJ
cord-016871-1mlamf20	330	25	5.3	5.3	CD
cord-016871-1mlamf20	330	26	-	-	SYM
cord-016871-1mlamf20	330	27	12	12	CD
cord-016871-1mlamf20	330	28	K	K	NNP
cord-016871-1mlamf20	330	29	dynes	dynes	NNP
cord-016871-1mlamf20	330	30	/	/	SYM
cord-016871-1mlamf20	330	31	cm	cm	NNP
cord-016871-1mlamf20	330	32	2	2	CD
cord-016871-1mlamf20	330	33	)	)	-RRB-
cord-016871-1mlamf20	330	34	.	.	.
cord-016871-1mlamf20	331	1	The	the	DT
cord-016871-1mlamf20	331	2	LY30	LY30	NNP
cord-016871-1mlamf20	331	3	is	be	VBZ
cord-016871-1mlamf20	331	4	the	the	DT
cord-016871-1mlamf20	331	5	percent	percent	NN
cord-016871-1mlamf20	331	6	of	of	IN
cord-016871-1mlamf20	331	7	amplitude	amplitude	NN
cord-016871-1mlamf20	331	8	reduction	reduction	NN
cord-016871-1mlamf20	331	9	at	at	IN
cord-016871-1mlamf20	331	10	30	30	CD
cord-016871-1mlamf20	331	11	min	min	NN
cord-016871-1mlamf20	331	12	after	after	IN
cord-016871-1mlamf20	331	13	the	the	DT
cord-016871-1mlamf20	331	14	MA	MA	NNP
cord-016871-1mlamf20	331	15	,	,	,
cord-016871-1mlamf20	331	16	and	and	CC
cord-016871-1mlamf20	331	17	is	be	VBZ
cord-016871-1mlamf20	331	18	elevated	elevate	VBN
cord-016871-1mlamf20	331	19	in	in	IN
cord-016871-1mlamf20	331	20	hyper	hyper	JJ
cord-016871-1mlamf20	331	21	fi	fi	NN
cord-016871-1mlamf20	331	22	brinolytic	brinolytic	JJ
cord-016871-1mlamf20	331	23	states	state	NNS
cord-016871-1mlamf20	331	24	(	(	-LRB-
cord-016871-1mlamf20	331	25	normal	normal	JJ
cord-016871-1mlamf20	331	26	range	range	NN
cord-016871-1mlamf20	331	27	0.0	0.0	CD
cord-016871-1mlamf20	331	28	-	-	HYPH
cord-016871-1mlamf20	331	29	7.5	7.5	CD
cord-016871-1mlamf20	331	30	%	%	NN
cord-016871-1mlamf20	331	31	)	)	-RRB-
cord-016871-1mlamf20	331	32	[	[	-LRB-
cord-016871-1mlamf20	331	33	55	55	CD
cord-016871-1mlamf20	331	34	]	]	-RRB-
cord-016871-1mlamf20	332	1	(	(	-LRB-
cord-016871-1mlamf20	332	2	Figs	fig	NNS
cord-016871-1mlamf20	332	3	.	.	.
cord-016871-1mlamf20	333	1	12.3	12.3	CD
cord-016871-1mlamf20	333	2	and	and	CC
cord-016871-1mlamf20	333	3	12.4	12.4	CD
cord-016871-1mlamf20	333	4	)	)	-RRB-
cord-016871-1mlamf20	333	5	.	.	.
cord-016871-1mlamf20	334	1	The	the	DT
cord-016871-1mlamf20	334	2	use	use	NN
cord-016871-1mlamf20	334	3	of	of	IN
cord-016871-1mlamf20	334	4	r	r	NNP
cord-016871-1mlamf20	334	5	-	-	HYPH
cord-016871-1mlamf20	334	6	TEG	TEG	NNP
cord-016871-1mlamf20	334	7	is	be	VBZ
cord-016871-1mlamf20	334	8	further	far	RBR
cord-016871-1mlamf20	334	9	facilitated	facilitate	VBN
cord-016871-1mlamf20	334	10	by	by	IN
cord-016871-1mlamf20	334	11	advanced	advanced	JJ
cord-016871-1mlamf20	334	12	software	software	NN
cord-016871-1mlamf20	334	13	that	that	WDT
cord-016871-1mlamf20	334	14	displays	display	VBZ
cord-016871-1mlamf20	334	15	the	the	DT
cord-016871-1mlamf20	334	16	r	r	NNP
cord-016871-1mlamf20	334	17	-	-	HYPH
cord-016871-1mlamf20	334	18	TEG	TEG	NNP
cord-016871-1mlamf20	334	19	tracing	tracing	NN
cord-016871-1mlamf20	334	20	as	as	IN
cord-016871-1mlamf20	334	21	the	the	DT
cord-016871-1mlamf20	334	22	test	test	NN
cord-016871-1mlamf20	334	23	is	be	VBZ
cord-016871-1mlamf20	334	24	being	be	VBG
cord-016871-1mlamf20	334	25	performed	perform	VBN
cord-016871-1mlamf20	334	26	,	,	,
cord-016871-1mlamf20	334	27	providing	provide	VBG
cord-016871-1mlamf20	334	28	physicians	physician	NNS
cord-016871-1mlamf20	334	29	with	with	IN
cord-016871-1mlamf20	334	30	"	"	``
cord-016871-1mlamf20	334	31	real	real	JJ
cord-016871-1mlamf20	334	32	time	time	NN
cord-016871-1mlamf20	334	33	"	"	''
cord-016871-1mlamf20	334	34	results	result	NNS
cord-016871-1mlamf20	334	35	.	.	.
cord-016871-1mlamf20	335	1	Cotton	cotton	NN
cord-016871-1mlamf20	335	2	et	et	FW
cord-016871-1mlamf20	335	3	al	al	NNP
cord-016871-1mlamf20	335	4	.	.	.
cord-016871-1mlamf20	336	1	report	report	VB
cord-016871-1mlamf20	336	2	that	that	IN
cord-016871-1mlamf20	336	3	early	early	JJ
cord-016871-1mlamf20	336	4	r	r	NNP
cord-016871-1mlamf20	336	5	-	-	HYPH
cord-016871-1mlamf20	336	6	TEG	teg	NN
cord-016871-1mlamf20	336	7	parameter	parameter	NN
cord-016871-1mlamf20	336	8	tracings	tracing	NNS
cord-016871-1mlamf20	336	9	(	(	-LRB-
cord-016871-1mlamf20	336	10	ACT	ACT	NNP
cord-016871-1mlamf20	336	11	,	,	,
cord-016871-1mlamf20	336	12	k	k	NNP
cord-016871-1mlamf20	336	13	-time	-time	NN
cord-016871-1mlamf20	336	14	and	and	CC
cord-016871-1mlamf20	336	15	r	r	NN
cord-016871-1mlamf20	336	16	-value	-value	CD
cord-016871-1mlamf20	336	17	)	)	-RRB-
cord-016871-1mlamf20	336	18	appeared	appear	VBD
cord-016871-1mlamf20	336	19	within	within	IN
cord-016871-1mlamf20	336	20	5	5	CD
cord-016871-1mlamf20	336	21	min	min	NN
cord-016871-1mlamf20	336	22	while	while	IN
cord-016871-1mlamf20	336	23	later	later	JJ
cord-016871-1mlamf20	336	24	values	value	NNS
cord-016871-1mlamf20	336	25	(	(	-LRB-
cord-016871-1mlamf20	336	26	-angle	-angle	NN
cord-016871-1mlamf20	336	27	,	,	,
cord-016871-1mlamf20	336	28	MA	MA	NNP
cord-016871-1mlamf20	336	29	)	)	-RRB-
cord-016871-1mlamf20	336	30	were	be	VBD
cord-016871-1mlamf20	336	31	seen	see	VBN
cord-016871-1mlamf20	336	32	within	within	IN
cord-016871-1mlamf20	336	33	15	15	CD
cord-016871-1mlamf20	336	34	min	min	NN
cord-016871-1mlamf20	336	35	,	,	,
cord-016871-1mlamf20	336	36	compared	compare	VBN
cord-016871-1mlamf20	336	37	to	to	IN
cord-016871-1mlamf20	336	38	CCT	CCT	NNP
cord-016871-1mlamf20	336	39	panels	panel	NNS
cord-016871-1mlamf20	336	40	,	,	,
cord-016871-1mlamf20	336	41	Fig	Fig	NNP
cord-016871-1mlamf20	336	42	.	.	.
cord-016871-1mlamf20	337	1	12.2	12.2	CD
cord-016871-1mlamf20	338	1	The	the	DT
cord-016871-1mlamf20	338	2	various	various	JJ
cord-016871-1mlamf20	338	3	sequential	sequential	JJ
cord-016871-1mlamf20	338	4	and	and	CC
cord-016871-1mlamf20	338	5	parallel	parallel	JJ
cord-016871-1mlamf20	338	6	measurements	measurement	NNS
cord-016871-1mlamf20	338	7	of	of	IN
cord-016871-1mlamf20	338	8	TEG	TEG	NNP
cord-016871-1mlamf20	338	9	and	and	CC
cord-016871-1mlamf20	338	10	ROTEM	ROTEM	NNP
cord-016871-1mlamf20	338	11	[	[	-LRB-
cord-016871-1mlamf20	338	12	4	4	CD
cord-016871-1mlamf20	338	13	]	]	-RRB-
cord-016871-1mlamf20	338	14	which	which	WDT
cord-016871-1mlamf20	338	15	were	be	VBD
cord-016871-1mlamf20	338	16	not	not	RB
cord-016871-1mlamf20	338	17	available	available	JJ
cord-016871-1mlamf20	338	18	until	until	IN
cord-016871-1mlamf20	338	19	48	48	CD
cord-016871-1mlamf20	338	20	min	min	NN
cord-016871-1mlamf20	338	21	[	[	-LRB-
cord-016871-1mlamf20	338	22	55	55	CD
cord-016871-1mlamf20	338	23	]	]	-RRB-
cord-016871-1mlamf20	338	24	.	.	.
cord-016871-1mlamf20	339	1	Installation	installation	NN
cord-016871-1mlamf20	339	2	of	of	IN
cord-016871-1mlamf20	339	3	graphical	graphical	JJ
cord-016871-1mlamf20	339	4	software	software	NN
cord-016871-1mlamf20	339	5	in	in	IN
cord-016871-1mlamf20	339	6	the	the	DT
cord-016871-1mlamf20	339	7	trauma	trauma	NN
cord-016871-1mlamf20	339	8	bay	bay	NN
cord-016871-1mlamf20	339	9	,	,	,
cord-016871-1mlamf20	339	10	operating	operate	VBG
cord-016871-1mlamf20	339	11	room	room	NN
cord-016871-1mlamf20	339	12	and	and	CC
cord-016871-1mlamf20	339	13	shock	shock	NN
cord-016871-1mlamf20	339	14	-	-	HYPH
cord-016871-1mlamf20	339	15	trauma	trauma	NN
cord-016871-1mlamf20	339	16	intensive	intensive	JJ
cord-016871-1mlamf20	339	17	care	care	NN
cord-016871-1mlamf20	339	18	unit	unit	NN
cord-016871-1mlamf20	339	19	computers	computer	NNS
cord-016871-1mlamf20	339	20	can	can	MD
cord-016871-1mlamf20	339	21	further	further	RB
cord-016871-1mlamf20	339	22	facilitate	facilitate	VB
cord-016871-1mlamf20	339	23	the	the	DT
cord-016871-1mlamf20	339	24	rapid	rapid	JJ
cord-016871-1mlamf20	339	25	access	access	NN
cord-016871-1mlamf20	339	26	to	to	IN
cord-016871-1mlamf20	339	27	TEG	TEG	NNP
cord-016871-1mlamf20	339	28	results	result	NNS
cord-016871-1mlamf20	339	29	[	[	-LRB-
cord-016871-1mlamf20	339	30	55	55	CD
cord-016871-1mlamf20	339	31	]	]	-RRB-
cord-016871-1mlamf20	339	32	.	.	.
cord-016871-1mlamf20	340	1	TEG	TEG	NNP
cord-016871-1mlamf20	340	2	data	data	NN
cord-016871-1mlamf20	340	3	results	result	NNS
cord-016871-1mlamf20	340	4	compare	compare	VBP
cord-016871-1mlamf20	340	5	well	well	RB
cord-016871-1mlamf20	340	6	to	to	IN
cord-016871-1mlamf20	340	7	the	the	DT
cord-016871-1mlamf20	340	8	previous	previous	JJ
cord-016871-1mlamf20	340	9	standard	standard	NN
cord-016871-1mlamf20	340	10	,	,	,
cord-016871-1mlamf20	340	11	CCTs	cct	NNS
cord-016871-1mlamf20	340	12	.	.	.
cord-016871-1mlamf20	341	1	In	in	IN
cord-016871-1mlamf20	341	2	2011	2011	CD
cord-016871-1mlamf20	341	3	,	,	,
cord-016871-1mlamf20	341	4	Cotton	Cotton	NNP
cord-016871-1mlamf20	341	5	et	et	NNP
cord-016871-1mlamf20	341	6	al	al	NNP
cord-016871-1mlamf20	341	7	.	.	NNP
cord-016871-1mlamf20	341	8	conducted	conduct	VBD
cord-016871-1mlamf20	341	9	a	a	DT
cord-016871-1mlamf20	341	10	pilot	pilot	NN
cord-016871-1mlamf20	341	11	study	study	NN
cord-016871-1mlamf20	341	12	of	of	IN
cord-016871-1mlamf20	341	13	272	272	CD
cord-016871-1mlamf20	341	14	patients	patient	NNS
cord-016871-1mlamf20	341	15	to	to	TO
cord-016871-1mlamf20	341	16	investigate	investigate	VB
cord-016871-1mlamf20	341	17	the	the	DT
cord-016871-1mlamf20	341	18	role	role	NN
cord-016871-1mlamf20	341	19	of	of	IN
cord-016871-1mlamf20	341	20	rapid	rapid	JJ
cord-016871-1mlamf20	341	21	thrombelastography	thrombelastography	NN
cord-016871-1mlamf20	341	22	(	(	-LRB-
cord-016871-1mlamf20	341	23	r	r	NNP
cord-016871-1mlamf20	341	24	-	-	HYPH
cord-016871-1mlamf20	341	25	TEG	TEG	NNP
cord-016871-1mlamf20	341	26	)	)	-RRB-
cord-016871-1mlamf20	341	27	in	in	IN
cord-016871-1mlamf20	341	28	(	(	-LRB-
cord-016871-1mlamf20	341	29	1	1	CD
cord-016871-1mlamf20	341	30	)	)	-RRB-
cord-016871-1mlamf20	341	31	assessing	assess	VBG
cord-016871-1mlamf20	341	32	speed	speed	NN
cord-016871-1mlamf20	341	33	of	of	IN
cord-016871-1mlamf20	341	34	results	result	NNS
cord-016871-1mlamf20	341	35	,	,	,
cord-016871-1mlamf20	341	36	(	(	-LRB-
cord-016871-1mlamf20	341	37	2	2	LS
cord-016871-1mlamf20	341	38	)	)	-RRB-
cord-016871-1mlamf20	341	39	correlation	correlation	NN
cord-016871-1mlamf20	341	40	with	with	IN
cord-016871-1mlamf20	341	41	CCT	CCT	NNP
cord-016871-1mlamf20	341	42	fi	fi	NNP
cord-016871-1mlamf20	341	43	ndings	nding	NNS
cord-016871-1mlamf20	341	44	,	,	,
cord-016871-1mlamf20	341	45	and	and	CC
cord-016871-1mlamf20	341	46	(	(	-LRB-
cord-016871-1mlamf20	341	47	3	3	LS
cord-016871-1mlamf20	341	48	)	)	-RRB-
cord-016871-1mlamf20	341	49	predictability	predictability	NN
cord-016871-1mlamf20	341	50	of	of	IN
cord-016871-1mlamf20	341	51	early	early	JJ
cord-016871-1mlamf20	341	52	transfusions	transfusion	NNS
cord-016871-1mlamf20	341	53	of	of	IN
cord-016871-1mlamf20	341	54	pRBCs	prbcs	RB
cord-016871-1mlamf20	341	55	,	,	,
cord-016871-1mlamf20	341	56	plasma	plasma	NN
cord-016871-1mlamf20	341	57	,	,	,
cord-016871-1mlamf20	341	58	and	and	CC
cord-016871-1mlamf20	341	59	platelets	platelet	NNS
cord-016871-1mlamf20	341	60	[	[	-LRB-
cord-016871-1mlamf20	341	61	55	55	CD
cord-016871-1mlamf20	341	62	]	]	-RRB-
cord-016871-1mlamf20	341	63	.	.	.
cord-016871-1mlamf20	342	1	Their	-PRON-	PRP$
cord-016871-1mlamf20	342	2	fi	fi	NN
cord-016871-1mlamf20	342	3	ndings	nding	NNS
cord-016871-1mlamf20	342	4	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	342	5	that	that	IN
cord-016871-1mlamf20	342	6	graphical	graphical	JJ
cord-016871-1mlamf20	342	7	r	r	NNP
cord-016871-1mlamf20	342	8	-	-	HYPH
cord-016871-1mlamf20	342	9	TEG	TEG	NNP
cord-016871-1mlamf20	342	10	is	be	VBZ
cord-016871-1mlamf20	342	11	available	available	JJ
cord-016871-1mlamf20	342	12	within	within	IN
cord-016871-1mlamf20	342	13	minutes	minute	NNS
cord-016871-1mlamf20	342	14	,	,	,
cord-016871-1mlamf20	342	15	an	an	DT
cord-016871-1mlamf20	342	16	improvement	improvement	NN
cord-016871-1mlamf20	342	17	compared	compare	VBN
cord-016871-1mlamf20	342	18	to	to	IN
cord-016871-1mlamf20	342	19	CCTs	cct	NNS
cord-016871-1mlamf20	342	20	.	.	.
cord-016871-1mlamf20	343	1	They	-PRON-	PRP
cord-016871-1mlamf20	343	2	also	also	RB
cord-016871-1mlamf20	343	3	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	343	4	that	that	IN
cord-016871-1mlamf20	343	5	ACT	ACT	NNP
cord-016871-1mlamf20	343	6	,	,	,
cord-016871-1mlamf20	343	7	r	r	NN
cord-016871-1mlamf20	343	8	-value	-value	CD
cord-016871-1mlamf20	343	9	and	and	CC
cord-016871-1mlamf20	343	10	k	k	NNP
cord-016871-1mlamf20	343	11	-time	-time	NNP
cord-016871-1mlamf20	343	12	strongly	strongly	RB
cord-016871-1mlamf20	343	13	correlated	correlate	VBD
cord-016871-1mlamf20	343	14	with	with	IN
cord-016871-1mlamf20	343	15	PT	PT	NNP
cord-016871-1mlamf20	343	16	,	,	,
cord-016871-1mlamf20	343	17	INR	INR	NNP
cord-016871-1mlamf20	343	18	,	,	,
cord-016871-1mlamf20	343	19	and	and	CC
cord-016871-1mlamf20	343	20	PTT	PTT	NNP
cord-016871-1mlamf20	343	21	.	.	.
cord-016871-1mlamf20	344	1	MA	MA	NNP
cord-016871-1mlamf20	344	2	and	and	CC
cord-016871-1mlamf20	344	3	-angle	-angle	NN
cord-016871-1mlamf20	344	4	strongly	strongly	RB
cord-016871-1mlamf20	344	5	correlated	correlate	VBD
cord-016871-1mlamf20	344	6	with	with	IN
cord-016871-1mlamf20	344	7	platelet	platelet	NN
cord-016871-1mlamf20	344	8	count	count	NN
cord-016871-1mlamf20	344	9	,	,	,
cord-016871-1mlamf20	344	10	and	and	CC
cord-016871-1mlamf20	344	11	ACT	ACT	NNP
cord-016871-1mlamf20	344	12	,	,	,
cord-016871-1mlamf20	345	1	r	r	LS
cord-016871-1mlamf20	345	2	-value	-value	NNP
cord-016871-1mlamf20	345	3	,	,	,
cord-016871-1mlamf20	345	4	-angle	-angle	CD
cord-016871-1mlamf20	345	5	and	and	CC
cord-016871-1mlamf20	345	6	MA	MA	NNP
cord-016871-1mlamf20	345	7	were	be	VBD
cord-016871-1mlamf20	345	8	predictive	predictive	JJ
cord-016871-1mlamf20	345	9	of	of	IN
cord-016871-1mlamf20	345	10	pRBC	prbc	NN
cord-016871-1mlamf20	345	11	,	,	,
cord-016871-1mlamf20	345	12	plasma	plasma	NN
cord-016871-1mlamf20	345	13	and	and	CC
cord-016871-1mlamf20	345	14	platelet	platelet	NN
cord-016871-1mlamf20	345	15	transfusions	transfusion	NNS
cord-016871-1mlamf20	345	16	within	within	IN
cord-016871-1mlamf20	345	17	the	the	DT
cord-016871-1mlamf20	345	18	fi	fi	NNP
cord-016871-1mlamf20	345	19	rst	rst	NNP
cord-016871-1mlamf20	345	20	2	2	CD
cord-016871-1mlamf20	345	21	h	h	NN
cord-016871-1mlamf20	345	22	of	of	IN
cord-016871-1mlamf20	345	23	arrival	arrival	NN
cord-016871-1mlamf20	345	24	.	.	.
cord-016871-1mlamf20	346	1	In	in	IN
cord-016871-1mlamf20	346	2	fact	fact	NN
cord-016871-1mlamf20	346	3	,	,	,
cord-016871-1mlamf20	346	4	an	an	DT
cord-016871-1mlamf20	346	5	ACT	act	NN
cord-016871-1mlamf20	346	6	>	>	SYM
cord-016871-1mlamf20	346	7	128	128	CD
cord-016871-1mlamf20	346	8	predicted	predict	VBD
cord-016871-1mlamf20	346	9	massive	massive	JJ
cord-016871-1mlamf20	346	10	transfusion	transfusion	NN
cord-016871-1mlamf20	346	11	in	in	IN
cord-016871-1mlamf20	346	12	the	the	DT
cord-016871-1mlamf20	346	13	fi	fi	NNP
cord-016871-1mlamf20	346	14	rst	rst	NNP
cord-016871-1mlamf20	346	15	6	6	CD
cord-016871-1mlamf20	346	16	h	h	NN
cord-016871-1mlamf20	346	17	and	and	CC
cord-016871-1mlamf20	346	18	an	an	DT
cord-016871-1mlamf20	346	19	ACT	act	NN
cord-016871-1mlamf20	346	20	<	<	XX
cord-016871-1mlamf20	346	21	105	105	CD
cord-016871-1mlamf20	346	22	predicted	predict	VBD
cord-016871-1mlamf20	346	23	patients	patient	NNS
cord-016871-1mlamf20	346	24	that	that	WDT
cord-016871-1mlamf20	346	25	did	do	VBD
cord-016871-1mlamf20	346	26	not	not	RB
cord-016871-1mlamf20	346	27	receive	receive	VB
cord-016871-1mlamf20	346	28	transfusions	transfusion	NNS
cord-016871-1mlamf20	346	29	in	in	IN
cord-016871-1mlamf20	346	30	the	the	DT
cord-016871-1mlamf20	346	31	fi	fi	NNP
cord-016871-1mlamf20	346	32	rst	rst	NNP
cord-016871-1mlamf20	346	33	24	24	CD
cord-016871-1mlamf20	346	34	h	h	NNP
cord-016871-1mlamf20	346	35	[	[	-LRB-
cord-016871-1mlamf20	346	36	55	55	CD
cord-016871-1mlamf20	346	37	]	]	-RRB-
cord-016871-1mlamf20	346	38	.	.	.
cord-016871-1mlamf20	347	1	In	in	IN
cord-016871-1mlamf20	347	2	addition	addition	NN
cord-016871-1mlamf20	347	3	,	,	,
cord-016871-1mlamf20	347	4	comparison	comparison	NN
cord-016871-1mlamf20	347	5	of	of	IN
cord-016871-1mlamf20	347	6	TEG	TEG	NNP
cord-016871-1mlamf20	347	7	and	and	CC
cord-016871-1mlamf20	347	8	CCT	CCT	NNP
cord-016871-1mlamf20	347	9	in	in	IN
cord-016871-1mlamf20	347	10	cardiopulmonary	cardiopulmonary	JJ
cord-016871-1mlamf20	347	11	bypass	bypass	NN
cord-016871-1mlamf20	347	12	patients	patient	NNS
cord-016871-1mlamf20	347	13	found	find	VBD
cord-016871-1mlamf20	347	14	that	that	IN
cord-016871-1mlamf20	347	15	TEG	TEG	NNP
cord-016871-1mlamf20	347	16	measures	measure	NNS
cord-016871-1mlamf20	347	17	were	be	VBD
cord-016871-1mlamf20	347	18	useful	useful	JJ
cord-016871-1mlamf20	347	19	surrogates	surrogate	NNS
cord-016871-1mlamf20	347	20	for	for	IN
cord-016871-1mlamf20	347	21	CCT	CCT	NNP
cord-016871-1mlamf20	347	22	values	value	NNS
cord-016871-1mlamf20	347	23	[	[	-LRB-
cord-016871-1mlamf20	347	24	57	57	CD
cord-016871-1mlamf20	347	25	]	]	-RRB-
cord-016871-1mlamf20	347	26	.	.	.
cord-016871-1mlamf20	348	1	Because	because	IN
cord-016871-1mlamf20	348	2	of	of	IN
cord-016871-1mlamf20	348	3	the	the	DT
cord-016871-1mlamf20	348	4	speed	speed	NN
cord-016871-1mlamf20	348	5	of	of	IN
cord-016871-1mlamf20	348	6	their	-PRON-	PRP$
cord-016871-1mlamf20	348	7	availability	availability	NN
cord-016871-1mlamf20	348	8	and	and	CC
cord-016871-1mlamf20	348	9	predictive	predictive	JJ
cord-016871-1mlamf20	348	10	ability	ability	NN
cord-016871-1mlamf20	348	11	,	,	,
cord-016871-1mlamf20	348	12	integrating	integrate	VBG
cord-016871-1mlamf20	348	13	TEG	TEG	NNP
cord-016871-1mlamf20	348	14	results	result	NNS
cord-016871-1mlamf20	348	15	in	in	IN
cord-016871-1mlamf20	348	16	MTPs	mtp	NNS
cord-016871-1mlamf20	348	17	can	can	MD
cord-016871-1mlamf20	348	18	strengthen	strengthen	VB
cord-016871-1mlamf20	348	19	decision	decision	NN
cord-016871-1mlamf20	348	20	-	-	HYPH
cord-016871-1mlamf20	348	21	making	making	NN
cord-016871-1mlamf20	348	22	and	and	CC
cord-016871-1mlamf20	348	23	management	management	NN
cord-016871-1mlamf20	348	24	of	of	IN
cord-016871-1mlamf20	348	25	patients	patient	NNS
cord-016871-1mlamf20	348	26	and	and	CC
cord-016871-1mlamf20	348	27	improve	improve	VB
cord-016871-1mlamf20	348	28	patient	patient	JJ
cord-016871-1mlamf20	348	29	outcomes	outcome	NNS
cord-016871-1mlamf20	348	30	.	.	.
cord-016871-1mlamf20	349	1	A	a	DT
cord-016871-1mlamf20	349	2	wide	wide	JJ
cord-016871-1mlamf20	349	3	array	array	NN
cord-016871-1mlamf20	349	4	of	of	IN
cord-016871-1mlamf20	349	5	evidence	evidence	NN
cord-016871-1mlamf20	349	6	exists	exist	VBZ
cord-016871-1mlamf20	349	7	in	in	IN
cord-016871-1mlamf20	349	8	surgical	surgical	JJ
cord-016871-1mlamf20	349	9	patients	patient	NNS
cord-016871-1mlamf20	349	10	in	in	IN
cord-016871-1mlamf20	349	11	support	support	NN
cord-016871-1mlamf20	349	12	of	of	IN
cord-016871-1mlamf20	349	13	TEG	TEG	NNP
cord-016871-1mlamf20	349	14	's	's	POS
cord-016871-1mlamf20	349	15	ability	ability	NN
cord-016871-1mlamf20	349	16	to	to	TO
cord-016871-1mlamf20	349	17	predict	predict	VB
cord-016871-1mlamf20	349	18	prognosis	prognosis	NN
cord-016871-1mlamf20	349	19	,	,	,
cord-016871-1mlamf20	349	20	and	and	CC
cord-016871-1mlamf20	349	21	in	in	IN
cord-016871-1mlamf20	349	22	some	some	DT
cord-016871-1mlamf20	349	23	instances	instance	NNS
cord-016871-1mlamf20	349	24	,	,	,
cord-016871-1mlamf20	349	25	guide	guide	NN
cord-016871-1mlamf20	349	26	therapy	therapy	NN
cord-016871-1mlamf20	349	27	that	that	WDT
cord-016871-1mlamf20	349	28	improves	improve	VBZ
cord-016871-1mlamf20	349	29	it	-PRON-	PRP
cord-016871-1mlamf20	349	30	.	.	.
cord-016871-1mlamf20	350	1	Table	table	NN
cord-016871-1mlamf20	350	2	12	12	CD
cord-016871-1mlamf20	350	3	.1	.1	NFP
cord-016871-1mlamf20	350	4	is	be	VBZ
cord-016871-1mlamf20	350	5	an	an	DT
cord-016871-1mlamf20	350	6	example	example	NN
cord-016871-1mlamf20	350	7	of	of	IN
cord-016871-1mlamf20	350	8	TEG	TEG	NNP
cord-016871-1mlamf20	350	9	-	-	HYPH
cord-016871-1mlamf20	350	10	guided	guide	VBN
cord-016871-1mlamf20	350	11	protocol	protocol	NN
cord-016871-1mlamf20	350	12	with	with	IN
cord-016871-1mlamf20	350	13	such	such	PDT
cord-016871-1mlamf20	350	14	an	an	DT
cord-016871-1mlamf20	350	15	aim	aim	NN
cord-016871-1mlamf20	350	16	.	.	.
cord-016871-1mlamf20	351	1	Platelet	platelet	NN
cord-016871-1mlamf20	351	2	dysfunction	dysfunction	NN
cord-016871-1mlamf20	351	3	in	in	IN
cord-016871-1mlamf20	351	4	cardiopulmonary	cardiopulmonary	JJ
cord-016871-1mlamf20	351	5	bypass	bypass	NN
cord-016871-1mlamf20	351	6	patients	patient	NNS
cord-016871-1mlamf20	351	7	has	have	VBZ
cord-016871-1mlamf20	351	8	been	be	VBN
cord-016871-1mlamf20	351	9	attributed	attribute	VBN
cord-016871-1mlamf20	351	10	to	to	IN
cord-016871-1mlamf20	351	11	microvascular	microvascular	JJ
cord-016871-1mlamf20	351	12	bleeding	bleeding	NN
cord-016871-1mlamf20	351	13	,	,	,
cord-016871-1mlamf20	351	14	and	and	CC
cord-016871-1mlamf20	351	15	TEG	TEG	NNP
cord-016871-1mlamf20	351	16	has	have	VBZ
cord-016871-1mlamf20	351	17	been	be	VBN
cord-016871-1mlamf20	351	18	used	use	VBN
cord-016871-1mlamf20	351	19	in	in	IN
cord-016871-1mlamf20	351	20	the	the	DT
cord-016871-1mlamf20	351	21	setting	setting	NN
cord-016871-1mlamf20	351	22	of	of	IN
cord-016871-1mlamf20	351	23	cardiac	cardiac	JJ
cord-016871-1mlamf20	351	24	surgery	surgery	NN
cord-016871-1mlamf20	351	25	as	as	IN
cord-016871-1mlamf20	351	26	a	a	DT
cord-016871-1mlamf20	351	27	predictor	predictor	NN
cord-016871-1mlamf20	351	28	of	of	IN
cord-016871-1mlamf20	351	29	worsening	worsen	VBG
cord-016871-1mlamf20	351	30	patient	patient	JJ
cord-016871-1mlamf20	351	31	outcomes	outcome	NNS
cord-016871-1mlamf20	351	32	due	due	JJ
cord-016871-1mlamf20	351	33	to	to	IN
cord-016871-1mlamf20	351	34	this	this	DT
cord-016871-1mlamf20	351	35	mechanism	mechanism	NN
cord-016871-1mlamf20	351	36	[	[	-LRB-
cord-016871-1mlamf20	351	37	17	17	CD
cord-016871-1mlamf20	351	38	]	]	-RRB-
cord-016871-1mlamf20	351	39	.	.	.
cord-016871-1mlamf20	352	1	Solomon	Solomon	NNP
cord-016871-1mlamf20	352	2	et	et	NNP
cord-016871-1mlamf20	352	3	al	al	NNP
cord-016871-1mlamf20	352	4	.	.	NNP
cord-016871-1mlamf20	352	5	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	352	6	that	that	IN
cord-016871-1mlamf20	352	7	fi	fi	NNP
cord-016871-1mlamf20	352	8	brinogen	brinogen	NNP
cord-016871-1mlamf20	352	9	clot	clot	NN
cord-016871-1mlamf20	352	10	elasticity	elasticity	NN
cord-016871-1mlamf20	352	11	assessed	assess	VBN
cord-016871-1mlamf20	352	12	by	by	IN
cord-016871-1mlamf20	352	13	TEG	TEG	NNP
cord-016871-1mlamf20	352	14	correlated	correlate	VBD
cord-016871-1mlamf20	352	15	to	to	IN
cord-016871-1mlamf20	352	16	fi	fi	NNP
cord-016871-1mlamf20	352	17	brinogen	brinogen	NNP
cord-016871-1mlamf20	352	18	concentration	concentration	NN
cord-016871-1mlamf20	352	19	in	in	IN
cord-016871-1mlamf20	352	20	cardiopulmonary	cardiopulmonary	JJ
cord-016871-1mlamf20	352	21	bypass	bypass	NN
cord-016871-1mlamf20	352	22	patients	patient	NNS
cord-016871-1mlamf20	352	23	[	[	-LRB-
cord-016871-1mlamf20	352	24	58	58	CD
cord-016871-1mlamf20	352	25	]	]	-RRB-
cord-016871-1mlamf20	352	26	.	.	.
cord-016871-1mlamf20	353	1	TEG	TEG	NNP
cord-016871-1mlamf20	353	2	has	have	VBZ
cord-016871-1mlamf20	353	3	been	be	VBN
cord-016871-1mlamf20	353	4	found	find	VBN
cord-016871-1mlamf20	353	5	to	to	TO
cord-016871-1mlamf20	353	6	predict	predict	VB
cord-016871-1mlamf20	353	7	the	the	DT
cord-016871-1mlamf20	353	8	risk	risk	NN
cord-016871-1mlamf20	353	9	of	of	IN
cord-016871-1mlamf20	353	10	postoperative	postoperative	JJ
cord-016871-1mlamf20	353	11	bleeding	bleeding	NN
cord-016871-1mlamf20	353	12	,	,	,
cord-016871-1mlamf20	353	13	and	and	CC
cord-016871-1mlamf20	353	14	has	have	VBZ
cord-016871-1mlamf20	353	15	been	be	VBN
cord-016871-1mlamf20	353	16	used	use	VBN
cord-016871-1mlamf20	353	17	to	to	TO
cord-016871-1mlamf20	353	18	direct	direct	VB
cord-016871-1mlamf20	353	19	desmopressin	desmopressin	NN
cord-016871-1mlamf20	353	20	therapy	therapy	NN
cord-016871-1mlamf20	353	21	and	and	CC
cord-016871-1mlamf20	353	22	FFP	FFP	NNP
cord-016871-1mlamf20	353	23	transfusion	transfusion	NN
cord-016871-1mlamf20	353	24	requirement	requirement	NN
cord-016871-1mlamf20	353	25	in	in	IN
cord-016871-1mlamf20	353	26	cardiopulmonary	cardiopulmonary	JJ
cord-016871-1mlamf20	353	27	bypass	bypass	NN
cord-016871-1mlamf20	353	28	patients	patient	NNS
cord-016871-1mlamf20	353	29	[	[	-LRB-
cord-016871-1mlamf20	353	30	17	17	CD
cord-016871-1mlamf20	353	31	]	]	-RRB-
cord-016871-1mlamf20	353	32	.	.	.
cord-016871-1mlamf20	354	1	TEG	TEG	NNP
cord-016871-1mlamf20	354	2	has	have	VBZ
cord-016871-1mlamf20	354	3	been	be	VBN
cord-016871-1mlamf20	354	4	shown	show	VBN
cord-016871-1mlamf20	354	5	to	to	TO
cord-016871-1mlamf20	354	6	be	be	VB
cord-016871-1mlamf20	354	7	useful	useful	JJ
cord-016871-1mlamf20	354	8	in	in	IN
cord-016871-1mlamf20	354	9	liver	liver	NN
cord-016871-1mlamf20	354	10	surgery	surgery	NN
cord-016871-1mlamf20	354	11	,	,	,
cord-016871-1mlamf20	354	12	especially	especially	RB
cord-016871-1mlamf20	354	13	in	in	IN
cord-016871-1mlamf20	354	14	transplantation	transplantation	NN
cord-016871-1mlamf20	354	15	.	.	.
cord-016871-1mlamf20	355	1	Unlike	unlike	IN
cord-016871-1mlamf20	355	2	other	other	JJ
cord-016871-1mlamf20	355	3	surgeries	surgery	NNS
cord-016871-1mlamf20	355	4	,	,	,
cord-016871-1mlamf20	355	5	liver	liver	NN
cord-016871-1mlamf20	355	6	surgery	surgery	NN
cord-016871-1mlamf20	355	7	poses	pose	VBZ
cord-016871-1mlamf20	355	8	the	the	DT
cord-016871-1mlamf20	355	9	additional	additional	JJ
cord-016871-1mlamf20	355	10	problem	problem	NN
cord-016871-1mlamf20	355	11	of	of	IN
cord-016871-1mlamf20	355	12	increased	increase	VBN
cord-016871-1mlamf20	355	13	risk	risk	NN
cord-016871-1mlamf20	355	14	of	of	IN
cord-016871-1mlamf20	355	15	coagulation	coagulation	NN
cord-016871-1mlamf20	355	16	factor	factor	NN
cord-016871-1mlamf20	355	17	de	de	FW
cord-016871-1mlamf20	355	18	fi	fi	FW
cord-016871-1mlamf20	355	19	ciencies	ciencie	NNS
cord-016871-1mlamf20	355	20	due	due	JJ
cord-016871-1mlamf20	355	21	to	to	IN
cord-016871-1mlamf20	355	22	hepatic	hepatic	JJ
cord-016871-1mlamf20	355	23	dysfunction	dysfunction	NN
cord-016871-1mlamf20	355	24	and	and	CC
cord-016871-1mlamf20	355	25	lack	lack	NN
cord-016871-1mlamf20	355	26	of	of	IN
cord-016871-1mlamf20	355	27	synthesis	synthesis	NN
cord-016871-1mlamf20	355	28	.	.	.
cord-016871-1mlamf20	356	1	TEG	TEG	NNP
cord-016871-1mlamf20	356	2	-	-	HYPH
cord-016871-1mlamf20	356	3	guided	guide	VBN
cord-016871-1mlamf20	356	4	transfusion	transfusion	NN
cord-016871-1mlamf20	356	5	algorithms	algorithm	NNS
cord-016871-1mlamf20	356	6	in	in	IN
cord-016871-1mlamf20	356	7	this	this	DT
cord-016871-1mlamf20	356	8	area	area	NN
cord-016871-1mlamf20	356	9	have	have	VBP
cord-016871-1mlamf20	356	10	been	be	VBN
cord-016871-1mlamf20	356	11	shown	show	VBN
cord-016871-1mlamf20	356	12	to	to	TO
cord-016871-1mlamf20	356	13	reduce	reduce	VB
cord-016871-1mlamf20	356	14	the	the	DT
cord-016871-1mlamf20	356	15	transfusion	transfusion	NN
cord-016871-1mlamf20	356	16	requirements	requirement	NNS
cord-016871-1mlamf20	356	17	in	in	IN
cord-016871-1mlamf20	356	18	such	such	JJ
cord-016871-1mlamf20	356	19	patients	patient	NNS
cord-016871-1mlamf20	356	20	[	[	-LRB-
cord-016871-1mlamf20	356	21	17	17	CD
cord-016871-1mlamf20	356	22	]	]	-RRB-
cord-016871-1mlamf20	356	23	.	.	.
cord-016871-1mlamf20	357	1	However	however	RB
cord-016871-1mlamf20	357	2	,	,	,
cord-016871-1mlamf20	357	3	Ogawa	Ogawa	NNP
cord-016871-1mlamf20	357	4	et	et	NNP
cord-016871-1mlamf20	357	5	al	al	NNP
cord-016871-1mlamf20	357	6	.	.	NNP
cord-016871-1mlamf20	357	7	's	's	POS
cord-016871-1mlamf20	357	8	prospective	prospective	JJ
cord-016871-1mlamf20	357	9	observational	observational	JJ
cord-016871-1mlamf20	357	10	study	study	NN
cord-016871-1mlamf20	357	11	of	of	IN
cord-016871-1mlamf20	357	12	26	26	CD
cord-016871-1mlamf20	357	13	patients	patient	NNS
cord-016871-1mlamf20	357	14	undergoing	undergo	VBG
cord-016871-1mlamf20	357	15	cardiac	cardiac	JJ
cord-016871-1mlamf20	357	16	surgery	surgery	NN
cord-016871-1mlamf20	357	17	did	do	VBD
cord-016871-1mlamf20	357	18	not	not	RB
cord-016871-1mlamf20	357	19	fi	fi	VB
cord-016871-1mlamf20	357	20	nd	nd	NNP
cord-016871-1mlamf20	357	21	a	a	DT
cord-016871-1mlamf20	357	22	signi	signi	NN
cord-016871-1mlamf20	357	23	fi	fi	NN
cord-016871-1mlamf20	357	24	ca	can	MD
cord-016871-1mlamf20	357	25	nt	not	RB
cord-016871-1mlamf20	357	26	correlation	correlation	VB
cord-016871-1mlamf20	357	27	between	between	IN
cord-016871-1mlamf20	357	28	TEG	TEG	NNP
cord-016871-1mlamf20	357	29	measures	measure	NNS
cord-016871-1mlamf20	357	30	and	and	CC
cord-016871-1mlamf20	357	31	volume	volume	NN
cord-016871-1mlamf20	357	32	of	of	IN
cord-016871-1mlamf20	357	33	intraoperative	intraoperative	JJ
cord-016871-1mlamf20	357	34	and	and	CC
cord-016871-1mlamf20	357	35	total	total	JJ
cord-016871-1mlamf20	357	36	transfusions	transfusion	NNS
cord-016871-1mlamf20	357	37	.	.	.
cord-016871-1mlamf20	358	1	Despite	despite	IN
cord-016871-1mlamf20	358	2	these	these	DT
cord-016871-1mlamf20	358	3	fi	fi	NNP
cord-016871-1mlamf20	358	4	ndings	nding	NNS
cord-016871-1mlamf20	358	5	,	,	,
cord-016871-1mlamf20	358	6	[	[	-LRB-
cord-016871-1mlamf20	358	7	59	59	CD
cord-016871-1mlamf20	358	8	]	]	-RRB-
cord-016871-1mlamf20	358	9	.	.	.
cord-016871-1mlamf20	359	1	They	-PRON-	PRP
cord-016871-1mlamf20	359	2	investigated	investigate	VBD
cord-016871-1mlamf20	359	3	thromboelastography	thromboelastography	NN
cord-016871-1mlamf20	359	4	in	in	IN
cord-016871-1mlamf20	359	5	cardiac	cardiac	JJ
cord-016871-1mlamf20	359	6	surgery	surgery	NN
cord-016871-1mlamf20	359	7	patients	patient	NNS
cord-016871-1mlamf20	359	8	and	and	CC
cord-016871-1mlamf20	359	9	found	find	VBD
cord-016871-1mlamf20	359	10	14	14	CD
cord-016871-1mlamf20	359	11	studies	study	NNS
cord-016871-1mlamf20	359	12	that	that	WDT
cord-016871-1mlamf20	359	13	provided	provide	VBD
cord-016871-1mlamf20	359	14	the	the	DT
cord-016871-1mlamf20	359	15	best	good	JJS
cord-016871-1mlamf20	359	16	evidence	evidence	NN
cord-016871-1mlamf20	359	17	.	.	.
cord-016871-1mlamf20	360	1	Their	-PRON-	PRP$
cord-016871-1mlamf20	360	2	synthesis	synthesis	NN
cord-016871-1mlamf20	360	3	concluded	conclude	VBD
cord-016871-1mlamf20	360	4	that	that	IN
cord-016871-1mlamf20	360	5	TEG	TEG	NNP
cord-016871-1mlamf20	360	6	can	can	MD
cord-016871-1mlamf20	360	7	guide	guide	VB
cord-016871-1mlamf20	360	8	transfusion	transfusion	NN
cord-016871-1mlamf20	360	9	therapy	therapy	NN
cord-016871-1mlamf20	360	10	algorithms	algorithm	NNS
cord-016871-1mlamf20	360	11	and	and	CC
cord-016871-1mlamf20	360	12	result	result	VB
cord-016871-1mlamf20	360	13	in	in	IN
cord-016871-1mlamf20	360	14	decreased	decrease	VBN
cord-016871-1mlamf20	360	15	blood	blood	NN
cord-016871-1mlamf20	360	16	component	component	NN
cord-016871-1mlamf20	360	17	requirements	requirement	NNS
cord-016871-1mlamf20	360	18	.	.	.
cord-016871-1mlamf20	361	1	In	in	IN
cord-016871-1mlamf20	361	2	orthopedic	orthopedic	JJ
cord-016871-1mlamf20	361	3	surgery	surgery	NN
cord-016871-1mlamf20	361	4	patients	patient	NNS
cord-016871-1mlamf20	361	5	,	,	,
cord-016871-1mlamf20	361	6	TEG	TEG	NNP
cord-016871-1mlamf20	361	7	was	be	VBD
cord-016871-1mlamf20	361	8	used	use	VBN
cord-016871-1mlamf20	361	9	in	in	IN
cord-016871-1mlamf20	361	10	a	a	DT
cord-016871-1mlamf20	361	11	prospective	prospective	JJ
cord-016871-1mlamf20	361	12	study	study	NN
cord-016871-1mlamf20	361	13	to	to	TO
cord-016871-1mlamf20	361	14	identify	identify	VB
cord-016871-1mlamf20	361	15	disturbed	disturb	VBN
cord-016871-1mlamf20	361	16	fi	fi	NNP
cord-016871-1mlamf20	361	17	brin	brin	NNP
cord-016871-1mlamf20	361	18	polymerization	polymerization	NN
cord-016871-1mlamf20	361	19	as	as	IN
cord-016871-1mlamf20	361	20	a	a	DT
cord-016871-1mlamf20	361	21	pathological	pathological	JJ
cord-016871-1mlamf20	361	22	mechanism	mechanism	NN
cord-016871-1mlamf20	361	23	in	in	IN
cord-016871-1mlamf20	361	24	dilutional	dilutional	JJ
cord-016871-1mlamf20	361	25	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	361	26	,	,	,
cord-016871-1mlamf20	361	27	and	and	CC
cord-016871-1mlamf20	361	28	to	to	TO
cord-016871-1mlamf20	361	29	rescue	rescue	VB
cord-016871-1mlamf20	361	30	this	this	DT
cord-016871-1mlamf20	361	31	state	state	NN
cord-016871-1mlamf20	361	32	with	with	IN
cord-016871-1mlamf20	361	33	fi	fi	NNP
cord-016871-1mlamf20	361	34	brinogen	brinogen	NNP
cord-016871-1mlamf20	361	35	administration	administration	NNP
cord-016871-1mlamf20	361	36	[	[	-LRB-
cord-016871-1mlamf20	361	37	60	60	CD
cord-016871-1mlamf20	361	38	]	]	-RRB-
cord-016871-1mlamf20	361	39	.	.	.
cord-016871-1mlamf20	362	1	However	however	RB
cord-016871-1mlamf20	362	2	,	,	,
cord-016871-1mlamf20	362	3	TEG	TEG	NNP
cord-016871-1mlamf20	362	4	has	have	VBZ
cord-016871-1mlamf20	362	5	been	be	VBN
cord-016871-1mlamf20	362	6	found	find	VBN
cord-016871-1mlamf20	362	7	to	to	TO
cord-016871-1mlamf20	362	8	be	be	VB
cord-016871-1mlamf20	362	9	less	less	RBR
cord-016871-1mlamf20	362	10	sensitive	sensitive	JJ
cord-016871-1mlamf20	362	11	for	for	IN
cord-016871-1mlamf20	362	12	certain	certain	JJ
cord-016871-1mlamf20	362	13	categories	category	NNS
cord-016871-1mlamf20	362	14	of	of	IN
cord-016871-1mlamf20	362	15	platelet	platelet	NN
cord-016871-1mlamf20	362	16	inhibition	inhibition	NN
cord-016871-1mlamf20	362	17	.	.	.
cord-016871-1mlamf20	363	1	In	in	IN
cord-016871-1mlamf20	363	2	addition	addition	NN
cord-016871-1mlamf20	363	3	,	,	,
cord-016871-1mlamf20	363	4	hemostatis	hemostatis	NNP
cord-016871-1mlamf20	363	5	point	point	NN
cord-016871-1mlamf20	363	6	of	of	IN
cord-016871-1mlamf20	363	7	care	care	NN
cord-016871-1mlamf20	363	8	tests	test	NNS
cord-016871-1mlamf20	363	9	such	such	JJ
cord-016871-1mlamf20	363	10	as	as	IN
cord-016871-1mlamf20	363	11	PFA-100	PFA-100	NNP
cord-016871-1mlamf20	363	12	and	and	CC
cord-016871-1mlamf20	363	13	TEG	TEG	NNP
cord-016871-1mlamf20	363	14	are	be	VBP
cord-016871-1mlamf20	363	15	affected	affect	VBN
cord-016871-1mlamf20	363	16	by	by	IN
cord-016871-1mlamf20	363	17	nonopiod	nonopiod	JJ
cord-016871-1mlamf20	363	18	analgesic	analgesic	JJ
cord-016871-1mlamf20	363	19	drugs	drug	NNS
cord-016871-1mlamf20	363	20	.	.	.
cord-016871-1mlamf20	364	1	Scharbert	Scharbert	NNP
cord-016871-1mlamf20	364	2	et	et	FW
cord-016871-1mlamf20	364	3	al	al	NNP
cord-016871-1mlamf20	364	4	.	.	.
cord-016871-1mlamf20	365	1	's	's	POS
cord-016871-1mlamf20	366	1	crossover	crossover	NN
cord-016871-1mlamf20	366	2	,	,	,
cord-016871-1mlamf20	366	3	double	double	RB
cord-016871-1mlamf20	366	4	-	-	HYPH
cord-016871-1mlamf20	366	5	blinded	blinded	JJ
cord-016871-1mlamf20	367	1	,	,	,
cord-016871-1mlamf20	367	2	placebo	placebo	NN
cord-016871-1mlamf20	367	3	controlled	control	VBN
cord-016871-1mlamf20	367	4	study	study	NN
cord-016871-1mlamf20	367	5	demonstrated	demonstrate	VBD
cord-016871-1mlamf20	367	6	that	that	IN
cord-016871-1mlamf20	367	7	in	in	IN
cord-016871-1mlamf20	367	8	low	low	JJ
cord-016871-1mlamf20	367	9	back	back	JJ
cord-016871-1mlamf20	367	10	pain	pain	NN
cord-016871-1mlamf20	367	11	patients	patient	NNS
cord-016871-1mlamf20	367	12	scheduled	schedule	VBN
cord-016871-1mlamf20	367	13	for	for	IN
cord-016871-1mlamf20	367	14	invasive	invasive	JJ
cord-016871-1mlamf20	367	15	pain	pain	NN
cord-016871-1mlamf20	367	16	therapy	therapy	NN
cord-016871-1mlamf20	367	17	,	,	,
cord-016871-1mlamf20	367	18	cytochalasin	cytochalasin	NNP
cord-016871-1mlamf20	367	19	d	d	NNP
cord-016871-1mlamf20	367	20	-modi	-modi	:
cord-016871-1mlamf20	367	21	fi	fi	NNP
cord-016871-1mlamf20	367	22	ed	ed	NNP
cord-016871-1mlamf20	367	23	thromboelastometry	thromboelastometry	NNP
cord-016871-1mlamf20	367	24	had	have	VBD
cord-016871-1mlamf20	367	25	a	a	DT
cord-016871-1mlamf20	367	26	low	low	JJ
cord-016871-1mlamf20	367	27	sensitivity	sensitivity	NN
cord-016871-1mlamf20	367	28	for	for	IN
cord-016871-1mlamf20	367	29	detecting	detect	VBG
cord-016871-1mlamf20	367	30	platelet	platelet	NN
cord-016871-1mlamf20	367	31	inhibition	inhibition	NN
cord-016871-1mlamf20	367	32	by	by	IN
cord-016871-1mlamf20	367	33	diclofenac	diclofenac	NNP
cord-016871-1mlamf20	367	34	[	[	-LRB-
cord-016871-1mlamf20	367	35	61	61	CD
cord-016871-1mlamf20	367	36	]	]	-RRB-
cord-016871-1mlamf20	367	37	.	.	.
cord-016871-1mlamf20	368	1	There	there	EX
cord-016871-1mlamf20	368	2	are	be	VBP
cord-016871-1mlamf20	368	3	hemostatic	hemostatic	JJ
cord-016871-1mlamf20	368	4	states	state	NNS
cord-016871-1mlamf20	368	5	unique	unique	JJ
cord-016871-1mlamf20	368	6	to	to	IN
cord-016871-1mlamf20	368	7	the	the	DT
cord-016871-1mlamf20	368	8	surgical	surgical	JJ
cord-016871-1mlamf20	368	9	patient	patient	NN
cord-016871-1mlamf20	368	10	as	as	IN
cord-016871-1mlamf20	368	11	a	a	DT
cord-016871-1mlamf20	368	12	result	result	NN
cord-016871-1mlamf20	368	13	of	of	IN
cord-016871-1mlamf20	368	14	medications	medication	NNS
cord-016871-1mlamf20	368	15	such	such	JJ
cord-016871-1mlamf20	368	16	as	as	IN
cord-016871-1mlamf20	368	17	warfarin	warfarin	NN
cord-016871-1mlamf20	368	18	,	,	,
cord-016871-1mlamf20	368	19	perioperative	perioperative	JJ
cord-016871-1mlamf20	368	20	bleeding	bleed	VBG
cord-016871-1mlamf20	368	21	especially	especially	RB
cord-016871-1mlamf20	368	22	in	in	IN
cord-016871-1mlamf20	368	23	high	high	JJ
cord-016871-1mlamf20	368	24	bleeding	bleed	VBG
cord-016871-1mlamf20	368	25	risk	risk	NN
cord-016871-1mlamf20	368	26	surgeries	surgery	NNS
cord-016871-1mlamf20	368	27	,	,	,
cord-016871-1mlamf20	368	28	and	and	CC
cord-016871-1mlamf20	368	29	emergent	emergent	JJ
cord-016871-1mlamf20	368	30	surgical	surgical	JJ
cord-016871-1mlamf20	368	31	indications	indication	NNS
cord-016871-1mlamf20	368	32	such	such	JJ
cord-016871-1mlamf20	368	33	as	as	IN
cord-016871-1mlamf20	368	34	trauma	trauma	NN
cord-016871-1mlamf20	368	35	.	.	.
cord-016871-1mlamf20	369	1	Various	various	JJ
cord-016871-1mlamf20	369	2	mechanisms	mechanism	NNS
cord-016871-1mlamf20	369	3	affect	affect	VBP
cord-016871-1mlamf20	369	4	coagulation	coagulation	NN
cord-016871-1mlamf20	369	5	cascades	cascade	VBZ
cord-016871-1mlamf20	369	6	in	in	IN
cord-016871-1mlamf20	369	7	these	these	DT
cord-016871-1mlamf20	369	8	patients	patient	NNS
cord-016871-1mlamf20	369	9	,	,	,
cord-016871-1mlamf20	369	10	and	and	CC
cord-016871-1mlamf20	369	11	techniques	technique	NNS
cord-016871-1mlamf20	369	12	from	from	IN
cord-016871-1mlamf20	369	13	the	the	DT
cord-016871-1mlamf20	369	14	standard	standard	JJ
cord-016871-1mlamf20	369	15	coagulation	coagulation	NN
cord-016871-1mlamf20	369	16	tests	test	NNS
cord-016871-1mlamf20	369	17	to	to	IN
cord-016871-1mlamf20	369	18	TEG	TEG	NNP
cord-016871-1mlamf20	369	19	are	be	VBP
cord-016871-1mlamf20	369	20	currently	currently	RB
cord-016871-1mlamf20	369	21	available	available	JJ
cord-016871-1mlamf20	369	22	.	.	.
cord-016871-1mlamf20	370	1	These	these	DT
cord-016871-1mlamf20	370	2	have	have	VBP
cord-016871-1mlamf20	370	3	shown	show	VBN
cord-016871-1mlamf20	370	4	mostly	mostly	RB
cord-016871-1mlamf20	370	5	success	success	NN
cord-016871-1mlamf20	370	6	in	in	IN
cord-016871-1mlamf20	370	7	predicting	predict	VBG
cord-016871-1mlamf20	370	8	the	the	DT
cord-016871-1mlamf20	370	9	course	course	NN
cord-016871-1mlamf20	370	10	of	of	IN
cord-016871-1mlamf20	370	11	the	the	DT
cord-016871-1mlamf20	370	12	patient	patient	NN
cord-016871-1mlamf20	370	13	and	and	CC
cord-016871-1mlamf20	370	14	guiding	guide	VBG
cord-016871-1mlamf20	370	15	therapy	therapy	NN
cord-016871-1mlamf20	370	16	.	.	.
cord-016871-1mlamf20	371	1	The	the	DT
cord-016871-1mlamf20	371	2	therapeutic	therapeutic	JJ
cord-016871-1mlamf20	371	3	options	option	NNS
cord-016871-1mlamf20	371	4	include	include	VBP
cord-016871-1mlamf20	371	5	various	various	JJ
cord-016871-1mlamf20	371	6	blood	blood	NN
cord-016871-1mlamf20	371	7	product	product	NN
cord-016871-1mlamf20	371	8	components	component	NNS
cord-016871-1mlamf20	371	9	,	,	,
cord-016871-1mlamf20	371	10	ranging	range	VBG
cord-016871-1mlamf20	371	11	from	from	IN
cord-016871-1mlamf20	371	12	whole	whole	JJ
cord-016871-1mlamf20	371	13	blood	blood	NN
cord-016871-1mlamf20	371	14	to	to	IN
cord-016871-1mlamf20	371	15	concentrations	concentration	NNS
cord-016871-1mlamf20	371	16	of	of	IN
cord-016871-1mlamf20	371	17	individual	individual	JJ
cord-016871-1mlamf20	371	18	factors	factor	NNS
cord-016871-1mlamf20	371	19	.	.	.
cord-016871-1mlamf20	372	1	Using	use	VBG
cord-016871-1mlamf20	372	2	physiological	physiological	JJ
cord-016871-1mlamf20	372	3	ratios	ratio	NNS
cord-016871-1mlamf20	372	4	of	of	IN
cord-016871-1mlamf20	372	5	pRBCs	prbcs	RB
cord-016871-1mlamf20	372	6	,	,	,
cord-016871-1mlamf20	372	7	FFP	FFP	NNP
cord-016871-1mlamf20	372	8	,	,	,
cord-016871-1mlamf20	372	9	and	and	CC
cord-016871-1mlamf20	372	10	platelets	platelet	NNS
cord-016871-1mlamf20	372	11	have	have	VBP
cord-016871-1mlamf20	372	12	improved	improve	VBN
cord-016871-1mlamf20	372	13	patient	patient	JJ
cord-016871-1mlamf20	372	14	survival	survival	NN
cord-016871-1mlamf20	372	15	in	in	IN
cord-016871-1mlamf20	372	16	the	the	DT
cord-016871-1mlamf20	372	17	massively	massively	RB
cord-016871-1mlamf20	372	18	hemorrhaging	hemorrhaging	JJ
cord-016871-1mlamf20	372	19	patient	patient	NN
cord-016871-1mlamf20	372	20	.	.	.
cord-016871-1mlamf20	373	1	However	however	RB
cord-016871-1mlamf20	373	2	,	,	,
cord-016871-1mlamf20	373	3	like	like	IN
cord-016871-1mlamf20	373	4	all	all	DT
cord-016871-1mlamf20	373	5	powerful	powerful	JJ
cord-016871-1mlamf20	373	6	therapy	therapy	NN
cord-016871-1mlamf20	373	7	,	,	,
cord-016871-1mlamf20	373	8	they	-PRON-	PRP
cord-016871-1mlamf20	373	9	are	be	VBP
cord-016871-1mlamf20	373	10	associated	associate	VBN
cord-016871-1mlamf20	373	11	with	with	IN
cord-016871-1mlamf20	373	12	adverse	adverse	JJ
cord-016871-1mlamf20	373	13	effects	effect	NNS
cord-016871-1mlamf20	373	14	.	.	.
cord-016871-1mlamf20	374	1	Preventative	preventative	JJ
cord-016871-1mlamf20	374	2	options	option	NNS
cord-016871-1mlamf20	374	3	,	,	,
cord-016871-1mlamf20	374	4	such	such	JJ
cord-016871-1mlamf20	374	5	as	as	IN
cord-016871-1mlamf20	374	6	decreasing	decrease	VBG
cord-016871-1mlamf20	374	7	storage	storage	NN
cord-016871-1mlamf20	374	8	lengths	length	NNS
cord-016871-1mlamf20	374	9	and	and	CC
cord-016871-1mlamf20	374	10	screening	screen	VBG
cord-016871-1mlamf20	374	11	for	for	IN
cord-016871-1mlamf20	374	12	infectious	infectious	JJ
cord-016871-1mlamf20	374	13	agents	agent	NNS
cord-016871-1mlamf20	374	14	have	have	VBP
cord-016871-1mlamf20	374	15	drastically	drastically	RB
cord-016871-1mlamf20	374	16	reduced	reduce	VBN
cord-016871-1mlamf20	374	17	these	these	DT
cord-016871-1mlamf20	374	18	risks	risk	NNS
cord-016871-1mlamf20	374	19	.	.	.
cord-016871-1mlamf20	375	1	Lastly	lastly	RB
cord-016871-1mlamf20	375	2	,	,	,
cord-016871-1mlamf20	375	3	administering	administer	VBG
cord-016871-1mlamf20	375	4	these	these	DT
cord-016871-1mlamf20	375	5	products	product	NNS
cord-016871-1mlamf20	375	6	in	in	IN
cord-016871-1mlamf20	375	7	a	a	DT
cord-016871-1mlamf20	375	8	rapid	rapid	JJ
cord-016871-1mlamf20	375	9	and	and	CC
cord-016871-1mlamf20	375	10	directed	directed	JJ
cord-016871-1mlamf20	375	11	fashion	fashion	NN
cord-016871-1mlamf20	375	12	would	would	MD
cord-016871-1mlamf20	375	13	not	not	RB
cord-016871-1mlamf20	375	14	be	be	VB
cord-016871-1mlamf20	375	15	feasible	feasible	JJ
cord-016871-1mlamf20	375	16	without	without	IN
cord-016871-1mlamf20	375	17	in	in	IN
cord-016871-1mlamf20	375	18	-	-	HYPH
cord-016871-1mlamf20	375	19	house	house	NN
cord-016871-1mlamf20	375	20	triage	triage	NN
cord-016871-1mlamf20	375	21	and	and	CC
cord-016871-1mlamf20	375	22	massive	massive	JJ
cord-016871-1mlamf20	375	23	transfusion	transfusion	NN
cord-016871-1mlamf20	375	24	protocols	protocol	NNS
cord-016871-1mlamf20	375	25	.	.	.
cord-016871-1mlamf20	376	1	These	these	DT
cord-016871-1mlamf20	376	2	algorithms	algorithm	NNS
cord-016871-1mlamf20	376	3	include	include	VBP
cord-016871-1mlamf20	376	4	steps	step	NNS
cord-016871-1mlamf20	376	5	that	that	WDT
cord-016871-1mlamf20	376	6	must	must	MD
cord-016871-1mlamf20	376	7	be	be	VB
cord-016871-1mlamf20	376	8	taken	take	VBN
cord-016871-1mlamf20	376	9	to	to	TO
cord-016871-1mlamf20	376	10	smooth	smooth	VB
cord-016871-1mlamf20	376	11	out	out	RP
cord-016871-1mlamf20	376	12	logistics	logistic	NNS
cord-016871-1mlamf20	376	13	of	of	IN
cord-016871-1mlamf20	376	14	urgent	urgent	JJ
cord-016871-1mlamf20	376	15	transfusions	transfusion	NNS
cord-016871-1mlamf20	376	16	,	,	,
cord-016871-1mlamf20	376	17	such	such	JJ
cord-016871-1mlamf20	376	18	as	as	IN
cord-016871-1mlamf20	376	19	anticipating	anticipate	VBG
cord-016871-1mlamf20	376	20	adequate	adequate	JJ
cord-016871-1mlamf20	376	21	thawing	thawing	NN
cord-016871-1mlamf20	376	22	times	time	NNS
cord-016871-1mlamf20	376	23	of	of	IN
cord-016871-1mlamf20	376	24	FFPs	ffp	NNS
cord-016871-1mlamf20	376	25	and	and	CC
cord-016871-1mlamf20	376	26	collaborating	collaborate	VBG
cord-016871-1mlamf20	376	27	with	with	IN
cord-016871-1mlamf20	376	28	blood	blood	NN
cord-016871-1mlamf20	376	29	banks	bank	NNS
cord-016871-1mlamf20	376	30	to	to	TO
cord-016871-1mlamf20	376	31	crosscheck	crosscheck	VB
cord-016871-1mlamf20	376	32	appropriateness	appropriateness	NN
cord-016871-1mlamf20	376	33	of	of	IN
cord-016871-1mlamf20	376	34	each	each	DT
cord-016871-1mlamf20	376	35	order	order	NN
cord-016871-1mlamf20	376	36	(	(	-LRB-
cord-016871-1mlamf20	376	37	Fig	fig	NN
cord-016871-1mlamf20	376	38	.	.	.
cord-016871-1mlamf20	376	39	12.5	12.5	CD
cord-016871-1mlamf20	376	40	)	)	-RRB-
cord-016871-1mlamf20	376	41	.	.	.
cord-016871-1mlamf20	377	1	Damage	damage	NN
cord-016871-1mlamf20	377	2	control	control	NN
cord-016871-1mlamf20	377	3	'	'	''
cord-016871-1mlamf20	377	4	:	:	:
cord-016871-1mlamf20	377	5	an	an	DT
cord-016871-1mlamf20	377	6	approach	approach	NN
cord-016871-1mlamf20	377	7	for	for	IN
cord-016871-1mlamf20	377	8	improved	improve	VBN
cord-016871-1mlamf20	377	9	survival	survival	NN
cord-016871-1mlamf20	377	10	in	in	IN
cord-016871-1mlamf20	377	11	exsanguinating	exsanguinate	VBG
cord-016871-1mlamf20	377	12	penetrating	penetrating	JJ
cord-016871-1mlamf20	377	13	abdominal	abdominal	JJ
cord-016871-1mlamf20	377	14	injury	injury	NN
cord-016871-1mlamf20	377	15	Management	Management	NNP
cord-016871-1mlamf20	377	16	of	of	IN
cord-016871-1mlamf20	377	17	the	the	DT
cord-016871-1mlamf20	377	18	major	major	JJ
cord-016871-1mlamf20	377	19	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	377	20	with	with	IN
cord-016871-1mlamf20	377	21	onset	onset	NN
cord-016871-1mlamf20	377	22	during	during	IN
cord-016871-1mlamf20	377	23	laparotomy	laparotomy	NN
cord-016871-1mlamf20	377	24	on	on	IN
cord-016871-1mlamf20	377	25	behalf	behalf	NN
cord-016871-1mlamf20	377	26	of	of	IN
cord-016871-1mlamf20	377	27	The	the	DT
cord-016871-1mlamf20	377	28	Dutch	dutch	JJ
cord-016871-1mlamf20	377	29	Peritonitis	Peritonitis	NNP
cord-016871-1mlamf20	377	30	Study	Study	NNP
cord-016871-1mlamf20	377	31	Group	Group	NNP
cord-016871-1mlamf20	377	32	.	.	.
cord-016871-1mlamf20	378	1	Comparison	comparison	NN
cord-016871-1mlamf20	378	2	of	of	IN
cord-016871-1mlamf20	378	3	on	on	IN
cord-016871-1mlamf20	378	4	-	-	HYPH
cord-016871-1mlamf20	378	5	demand	demand	NN
cord-016871-1mlamf20	378	6	versus	versus	IN
cord-016871-1mlamf20	378	7	planned	planned	JJ
cord-016871-1mlamf20	378	8	relaparotomy	relaparotomy	NN
cord-016871-1mlamf20	378	9	strategy	strategy	NN
cord-016871-1mlamf20	378	10	in	in	IN
cord-016871-1mlamf20	378	11	patients	patient	NNS
cord-016871-1mlamf20	378	12	with	with	IN
cord-016871-1mlamf20	378	13	severe	severe	JJ
cord-016871-1mlamf20	378	14	peritonitis	peritonitis	NN
cord-016871-1mlamf20	378	15	Management	management	NN
cord-016871-1mlamf20	378	16	of	of	IN
cord-016871-1mlamf20	378	17	major	major	JJ
cord-016871-1mlamf20	378	18	blood	blood	NN
cord-016871-1mlamf20	378	19	loss	loss	NN
cord-016871-1mlamf20	378	20	:	:	:
cord-016871-1mlamf20	378	21	an	an	DT
cord-016871-1mlamf20	378	22	update	update	NN
cord-016871-1mlamf20	378	23	Massive	massive	JJ
cord-016871-1mlamf20	378	24	transfusion	transfusion	NN
cord-016871-1mlamf20	378	25	protocols	protocol	NNS
cord-016871-1mlamf20	378	26	for	for	IN
cord-016871-1mlamf20	378	27	patients	patient	NNS
cord-016871-1mlamf20	378	28	with	with	IN
cord-016871-1mlamf20	378	29	substantial	substantial	JJ
cord-016871-1mlamf20	378	30	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	379	1	Prede	prede	NN
cord-016871-1mlamf20	379	2	fi	fi	NN
cord-016871-1mlamf20	379	3	ned	ned	NN
cord-016871-1mlamf20	380	1	massive	massive	JJ
cord-016871-1mlamf20	380	2	transfusion	transfusion	NN
cord-016871-1mlamf20	380	3	protocols	protocol	NNS
cord-016871-1mlamf20	380	4	are	be	VBP
cord-016871-1mlamf20	380	5	associated	associate	VBN
cord-016871-1mlamf20	380	6	with	with	IN
cord-016871-1mlamf20	380	7	a	a	DT
cord-016871-1mlamf20	380	8	reduction	reduction	NN
cord-016871-1mlamf20	380	9	in	in	IN
cord-016871-1mlamf20	380	10	organ	organ	NN
cord-016871-1mlamf20	380	11	failure	failure	NN
cord-016871-1mlamf20	380	12	and	and	CC
cord-016871-1mlamf20	380	13	post	post	JJ
cord-016871-1mlamf20	380	14	-	-	JJ
cord-016871-1mlamf20	380	15	injury	injury	JJ
cord-016871-1mlamf20	380	16	complications	complication	NNS
cord-016871-1mlamf20	380	17	Damage	damage	VBP
cord-016871-1mlamf20	380	18	control	control	NN
cord-016871-1mlamf20	380	19	hematology	hematology	NN
cord-016871-1mlamf20	380	20	:	:	:
cord-016871-1mlamf20	380	21	the	the	DT
cord-016871-1mlamf20	380	22	impact	impact	NN
cord-016871-1mlamf20	380	23	of	of	IN
cord-016871-1mlamf20	380	24	a	a	DT
cord-016871-1mlamf20	380	25	trauma	trauma	NN
cord-016871-1mlamf20	380	26	exsanguination	exsanguination	NN
cord-016871-1mlamf20	380	27	protocol	protocol	NN
cord-016871-1mlamf20	380	28	on	on	IN
cord-016871-1mlamf20	380	29	survival	survival	NN
cord-016871-1mlamf20	380	30	and	and	CC
cord-016871-1mlamf20	380	31	blood	blood	NN
cord-016871-1mlamf20	380	32	product	product	NN
cord-016871-1mlamf20	380	33	utilization	utilization	NN
cord-016871-1mlamf20	381	1	A	a	DT
cord-016871-1mlamf20	381	2	massive	massive	JJ
cord-016871-1mlamf20	381	3	transfusion	transfusion	NN
cord-016871-1mlamf20	381	4	protocol	protocol	NN
cord-016871-1mlamf20	381	5	to	to	TO
cord-016871-1mlamf20	381	6	decrease	decrease	VB
cord-016871-1mlamf20	381	7	blood	blood	NN
cord-016871-1mlamf20	381	8	component	component	NN
cord-016871-1mlamf20	381	9	use	use	NN
cord-016871-1mlamf20	381	10	and	and	CC
cord-016871-1mlamf20	381	11	costs	cost	VBZ
cord-016871-1mlamf20	381	12	Initial	initial	JJ
cord-016871-1mlamf20	381	13	experiences	experience	NNS
cord-016871-1mlamf20	381	14	with	with	IN
cord-016871-1mlamf20	381	15	point	point	NN
cord-016871-1mlamf20	381	16	-	-	HYPH
cord-016871-1mlamf20	381	17	of	of	IN
cord-016871-1mlamf20	381	18	-	-	HYPH
cord-016871-1mlamf20	381	19	care	care	NN
cord-016871-1mlamf20	381	20	rapid	rapid	JJ
cord-016871-1mlamf20	381	21	thrombelastography	thrombelastography	NN
cord-016871-1mlamf20	381	22	for	for	IN
cord-016871-1mlamf20	381	23	management	management	NN
cord-016871-1mlamf20	381	24	of	of	IN
cord-016871-1mlamf20	381	25	life	life	NN
cord-016871-1mlamf20	381	26	-	-	HYPH
cord-016871-1mlamf20	381	27	threatening	threaten	VBG
cord-016871-1mlamf20	381	28	postinjury	postinjury	NN
cord-016871-1mlamf20	381	29	coagulopathy	coagulopathy	NNP
cord-016871-1mlamf20	381	30	Emergency	Emergency	NNP
cord-016871-1mlamf20	381	31	department	department	NN
cord-016871-1mlamf20	381	32	blood	blood	NN
cord-016871-1mlamf20	381	33	transfusion	transfusion	NN
cord-016871-1mlamf20	381	34	predicts	predict	VBZ
cord-016871-1mlamf20	381	35	early	early	JJ
cord-016871-1mlamf20	381	36	massive	massive	JJ
cord-016871-1mlamf20	381	37	transfusion	transfusion	NN
cord-016871-1mlamf20	381	38	and	and	CC
cord-016871-1mlamf20	381	39	early	early	JJ
cord-016871-1mlamf20	381	40	blood	blood	NN
cord-016871-1mlamf20	381	41	component	component	NN
cord-016871-1mlamf20	381	42	requirement	requirement	NN
cord-016871-1mlamf20	382	1	The	the	DT
cord-016871-1mlamf20	382	2	impact	impact	NN
cord-016871-1mlamf20	382	3	of	of	IN
cord-016871-1mlamf20	382	4	uncrossmatched	uncrossmatched	JJ
cord-016871-1mlamf20	382	5	blood	blood	NN
cord-016871-1mlamf20	382	6	transfusion	transfusion	NN
cord-016871-1mlamf20	382	7	on	on	IN
cord-016871-1mlamf20	382	8	the	the	DT
cord-016871-1mlamf20	382	9	need	need	NN
cord-016871-1mlamf20	382	10	for	for	IN
cord-016871-1mlamf20	382	11	massive	massive	JJ
cord-016871-1mlamf20	382	12	transfusion	transfusion	NN
cord-016871-1mlamf20	382	13	and	and	CC
cord-016871-1mlamf20	382	14	mortality	mortality	NN
cord-016871-1mlamf20	382	15	:	:	:
cord-016871-1mlamf20	382	16	analysis	analysis	NN
cord-016871-1mlamf20	382	17	of	of	IN
cord-016871-1mlamf20	382	18	5166	5166	CD
cord-016871-1mlamf20	382	19	uncross	uncross	VB
cord-016871-1mlamf20	382	20	-	-	HYPH
cord-016871-1mlamf20	382	21	matched	match	VBN
cord-016871-1mlamf20	382	22	units	unit	NNS
cord-016871-1mlamf20	382	23	Resuscitation	Resuscitation	NNP
cord-016871-1mlamf20	382	24	of	of	IN
cord-016871-1mlamf20	382	25	the	the	DT
cord-016871-1mlamf20	382	26	trauma	trauma	NN
cord-016871-1mlamf20	382	27	patient	patient	NN
cord-016871-1mlamf20	382	28	:	:	:
cord-016871-1mlamf20	382	29	tell	tell	VB
cord-016871-1mlamf20	382	30	me	-PRON-	PRP
cord-016871-1mlamf20	382	31	a	a	DT
cord-016871-1mlamf20	382	32	trigger	trigger	NN
cord-016871-1mlamf20	382	33	for	for	IN
cord-016871-1mlamf20	382	34	early	early	JJ
cord-016871-1mlamf20	382	35	haemostatic	haemostatic	JJ
cord-016871-1mlamf20	382	36	resuscitation	resuscitation	NN
cord-016871-1mlamf20	382	37	please	please	UH
cord-016871-1mlamf20	382	38	!	!	.
cord-016871-1mlamf20	383	1	Crit	Crit	NNP
cord-016871-1mlamf20	383	2	Care	Care	NNP
cord-016871-1mlamf20	383	3	Room	room	NN
cord-016871-1mlamf20	383	4	for	for	IN
cord-016871-1mlamf20	383	5	performance	performance	NN
cord-016871-1mlamf20	383	6	improvement	improvement	NN
cord-016871-1mlamf20	383	7	:	:	:
cord-016871-1mlamf20	383	8	provider	provider	NN
cord-016871-1mlamf20	383	9	-	-	HYPH
cord-016871-1mlamf20	383	10	related	relate	VBN
cord-016871-1mlamf20	383	11	factors	factor	NNS
cord-016871-1mlamf20	383	12	associated	associate	VBN
cord-016871-1mlamf20	383	13	with	with	IN
cord-016871-1mlamf20	383	14	poor	poor	JJ
cord-016871-1mlamf20	383	15	outcomes	outcome	NNS
cord-016871-1mlamf20	383	16	in	in	IN
cord-016871-1mlamf20	383	17	massive	massive	JJ
cord-016871-1mlamf20	383	18	transfusion	transfusion	NN
cord-016871-1mlamf20	383	19	Damage	damage	NN
cord-016871-1mlamf20	383	20	control	control	NN
cord-016871-1mlamf20	383	21	resuscitation	resuscitation	NN
cord-016871-1mlamf20	383	22	reduces	reduce	VBZ
cord-016871-1mlamf20	383	23	resuscitation	resuscitation	NN
cord-016871-1mlamf20	383	24	volumes	volume	NNS
cord-016871-1mlamf20	383	25	and	and	CC
cord-016871-1mlamf20	383	26	improves	improve	VBZ
cord-016871-1mlamf20	383	27	survival	survival	NN
cord-016871-1mlamf20	383	28	in	in	IN
cord-016871-1mlamf20	383	29	390	390	CD
cord-016871-1mlamf20	383	30	damage	damage	NN
cord-016871-1mlamf20	383	31	control	control	NN
cord-016871-1mlamf20	383	32	laparotomy	laparotomy	NN
cord-016871-1mlamf20	383	33	patients	patient	NNS
cord-016871-1mlamf20	383	34	Damage	damage	VB
cord-016871-1mlamf20	383	35	control	control	NN
cord-016871-1mlamf20	383	36	resuscitation	resuscitation	NN
cord-016871-1mlamf20	383	37	for	for	IN
cord-016871-1mlamf20	383	38	vascular	vascular	JJ
cord-016871-1mlamf20	383	39	surgery	surgery	NN
cord-016871-1mlamf20	383	40	in	in	IN
cord-016871-1mlamf20	383	41	a	a	DT
cord-016871-1mlamf20	383	42	combat	combat	NN
cord-016871-1mlamf20	383	43	support	support	NN
cord-016871-1mlamf20	383	44	hospital	hospital	NN
cord-016871-1mlamf20	383	45	Resuscitation	resuscitation	NN
cord-016871-1mlamf20	383	46	and	and	CC
cord-016871-1mlamf20	383	47	monitoring	monitoring	NN
cord-016871-1mlamf20	383	48	in	in	IN
cord-016871-1mlamf20	383	49	gastrointestinal	gastrointestinal	JJ
cord-016871-1mlamf20	383	50	bleeding	bleed	VBG
cord-016871-1mlamf20	383	51	The	the	DT
cord-016871-1mlamf20	383	52	surgical	surgical	JJ
cord-016871-1mlamf20	383	53	application	application	NN
cord-016871-1mlamf20	383	54	of	of	IN
cord-016871-1mlamf20	383	55	point	point	NN
cord-016871-1mlamf20	383	56	-	-	HYPH
cord-016871-1mlamf20	383	57	of	of	IN
cord-016871-1mlamf20	383	58	-	-	HYPH
cord-016871-1mlamf20	383	59	care	care	NN
cord-016871-1mlamf20	383	60	haemostasis	haemostasis	NN
cord-016871-1mlamf20	383	61	and	and	CC
cord-016871-1mlamf20	383	62	platelet	platelet	NN
cord-016871-1mlamf20	383	63	function	function	NN
cord-016871-1mlamf20	383	64	testing	test	VBG
cord-016871-1mlamf20	383	65	Proactive	Proactive	NNP
cord-016871-1mlamf20	383	66	administration	administration	NN
cord-016871-1mlamf20	383	67	of	of	IN
cord-016871-1mlamf20	383	68	platelets	platelet	NNS
cord-016871-1mlamf20	383	69	and	and	CC
cord-016871-1mlamf20	383	70	plasma	plasma	NN
cord-016871-1mlamf20	383	71	for	for	IN
cord-016871-1mlamf20	383	72	patients	patient	NNS
cord-016871-1mlamf20	383	73	with	with	IN
cord-016871-1mlamf20	383	74	a	a	DT
cord-016871-1mlamf20	383	75	ruptured	ruptured	JJ
cord-016871-1mlamf20	383	76	abdominal	abdominal	JJ
cord-016871-1mlamf20	383	77	aortic	aortic	JJ
cord-016871-1mlamf20	383	78	aneurysm	aneurysm	NN
cord-016871-1mlamf20	383	79	:	:	:
cord-016871-1mlamf20	383	80	evaluating	evaluate	VBG
cord-016871-1mlamf20	383	81	a	a	DT
cord-016871-1mlamf20	383	82	change	change	NN
cord-016871-1mlamf20	383	83	in	in	IN
cord-016871-1mlamf20	383	84	transfusion	transfusion	NN
cord-016871-1mlamf20	383	85	practice	practice	NN
cord-016871-1mlamf20	383	86	Effect	effect	NN
cord-016871-1mlamf20	383	87	of	of	IN
cord-016871-1mlamf20	383	88	early	early	JJ
cord-016871-1mlamf20	383	89	plasma	plasma	NN
cord-016871-1mlamf20	383	90	transfusion	transfusion	NN
cord-016871-1mlamf20	383	91	on	on	IN
cord-016871-1mlamf20	383	92	mortality	mortality	NN
cord-016871-1mlamf20	383	93	in	in	IN
cord-016871-1mlamf20	383	94	patients	patient	NNS
cord-016871-1mlamf20	383	95	with	with	IN
cord-016871-1mlamf20	383	96	ruptured	ruptured	JJ
cord-016871-1mlamf20	383	97	abdominal	abdominal	JJ
cord-016871-1mlamf20	383	98	aortic	aortic	JJ
cord-016871-1mlamf20	383	99	aneurysm	aneurysm	NN
cord-016871-1mlamf20	383	100	Trauma	trauma	NN
cord-016871-1mlamf20	383	101	Registry	Registry	NNP
cord-016871-1mlamf20	383	102	of	of	IN
cord-016871-1mlamf20	383	103	DGU	DGU	NNP
cord-016871-1mlamf20	383	104	.	.	.
cord-016871-1mlamf20	384	1	High	high	JJ
cord-016871-1mlamf20	384	2	plasma	plasma	NN
cord-016871-1mlamf20	384	3	to	to	IN
cord-016871-1mlamf20	384	4	red	red	JJ
cord-016871-1mlamf20	384	5	blood	blood	NN
cord-016871-1mlamf20	384	6	cell	cell	NN
cord-016871-1mlamf20	384	7	ratios	ratio	NNS
cord-016871-1mlamf20	384	8	are	be	VBP
cord-016871-1mlamf20	384	9	associated	associate	VBN
cord-016871-1mlamf20	384	10	with	with	IN
cord-016871-1mlamf20	384	11	lower	low	JJR
cord-016871-1mlamf20	384	12	mortality	mortality	NN
cord-016871-1mlamf20	384	13	rates	rate	NNS
cord-016871-1mlamf20	384	14	in	in	IN
cord-016871-1mlamf20	384	15	patients	patient	NNS
cord-016871-1mlamf20	384	16	receiving	receive	VBG
cord-016871-1mlamf20	384	17	multiple	multiple	JJ
cord-016871-1mlamf20	384	18	transfusion	transfusion	NN
cord-016871-1mlamf20	384	19	(	(	-LRB-
cord-016871-1mlamf20	384	20	4	4	CD
cord-016871-1mlamf20	384	21	£	£	$
cord-016871-1mlamf20	384	22	red	red	JJ
cord-016871-1mlamf20	384	23	blood	blood	NN
cord-016871-1mlamf20	384	24	cell	cell	NN
cord-016871-1mlamf20	384	25	units	unit	NNS
cord-016871-1mlamf20	384	26	<	<	XX
cord-016871-1mlamf20	384	27	10	10	CD
cord-016871-1mlamf20	384	28	)	)	-RRB-
cord-016871-1mlamf20	384	29	during	during	IN
cord-016871-1mlamf20	384	30	acute	acute	JJ
cord-016871-1mlamf20	384	31	trauma	trauma	NN
cord-016871-1mlamf20	384	32	resuscitation	resuscitation	NN
cord-016871-1mlamf20	384	33	Indications	indication	NNS
cord-016871-1mlamf20	384	34	for	for	IN
cord-016871-1mlamf20	384	35	early	early	JJ
cord-016871-1mlamf20	384	36	fresh	fresh	JJ
cord-016871-1mlamf20	384	37	frozen	frozen	JJ
cord-016871-1mlamf20	384	38	plasma	plasma	NN
cord-016871-1mlamf20	384	39	,	,	,
cord-016871-1mlamf20	384	40	cryoprecipitate	cryoprecipitate	NNP
cord-016871-1mlamf20	384	41	,	,	,
cord-016871-1mlamf20	384	42	and	and	CC
cord-016871-1mlamf20	384	43	platelet	platelet	NN
cord-016871-1mlamf20	384	44	transfusion	transfusion	NN
cord-016871-1mlamf20	384	45	in	in	IN
cord-016871-1mlamf20	384	46	trauma	trauma	NN
cord-016871-1mlamf20	384	47	Instituting	institute	VBG
cord-016871-1mlamf20	384	48	a	a	DT
cord-016871-1mlamf20	384	49	thawed	thaw	VBN
cord-016871-1mlamf20	384	50	plasma	plasma	NN
cord-016871-1mlamf20	384	51	procedure	procedure	NN
cord-016871-1mlamf20	384	52	:	:	:
cord-016871-1mlamf20	384	53	it	-PRON-	PRP
cord-016871-1mlamf20	384	54	just	just	RB
cord-016871-1mlamf20	384	55	makes	make	VBZ
cord-016871-1mlamf20	384	56	sense	sense	NN
cord-016871-1mlamf20	384	57	and	and	CC
cord-016871-1mlamf20	384	58	saves	save	VBZ
cord-016871-1mlamf20	384	59	cents	cent	NNS
cord-016871-1mlamf20	384	60	Blood	blood	NN
cord-016871-1mlamf20	384	61	conservation	conservation	NN
cord-016871-1mlamf20	384	62	for	for	IN
cord-016871-1mlamf20	384	63	critically	critically	RB
cord-016871-1mlamf20	384	64	ill	ill	JJ
cord-016871-1mlamf20	384	65	patients	patient	NNS
cord-016871-1mlamf20	385	1	A	a	DT
cord-016871-1mlamf20	385	2	prospective	prospective	JJ
cord-016871-1mlamf20	385	3	study	study	NN
cord-016871-1mlamf20	385	4	of	of	IN
cord-016871-1mlamf20	385	5	anemia	anemia	NN
cord-016871-1mlamf20	385	6	status	status	NN
cord-016871-1mlamf20	385	7	,	,	,
cord-016871-1mlamf20	385	8	hemoglobin	hemoglobin	NN
cord-016871-1mlamf20	385	9	concentration	concentration	NN
cord-016871-1mlamf20	385	10	,	,	,
cord-016871-1mlamf20	385	11	and	and	CC
cord-016871-1mlamf20	385	12	mortality	mortality	NN
cord-016871-1mlamf20	385	13	in	in	IN
cord-016871-1mlamf20	385	14	an	an	DT
cord-016871-1mlamf20	385	15	elderly	elderly	JJ
cord-016871-1mlamf20	385	16	cohort	cohort	NN
cord-016871-1mlamf20	385	17	Transfusions	transfusion	NNS
cord-016871-1mlamf20	385	18	in	in	IN
cord-016871-1mlamf20	385	19	surgical	surgical	JJ
cord-016871-1mlamf20	385	20	patients	patient	NNS
cord-016871-1mlamf20	386	1	Intraoperative	intraoperative	JJ
cord-016871-1mlamf20	386	2	autotransfusion	autotransfusion	NN
cord-016871-1mlamf20	386	3	in	in	IN
cord-016871-1mlamf20	386	4	abdominal	abdominal	JJ
cord-016871-1mlamf20	386	5	aortic	aortic	JJ
cord-016871-1mlamf20	386	6	aneurysm	aneurysm	NN
cord-016871-1mlamf20	386	7	surgery	surgery	NN
cord-016871-1mlamf20	386	8	Transfusion	Transfusion	NNP
cord-016871-1mlamf20	386	9	Requirements	Requirements	NNPS
cord-016871-1mlamf20	386	10	in	in	IN
cord-016871-1mlamf20	386	11	Critical	Critical	NNP
cord-016871-1mlamf20	386	12	Care	Care	NNP
cord-016871-1mlamf20	386	13	Investigators	Investigators	NNPS
cord-016871-1mlamf20	386	14	for	for	IN
cord-016871-1mlamf20	386	15	the	the	DT
cord-016871-1mlamf20	386	16	Canadian	Canadian	NNP
cord-016871-1mlamf20	386	17	Critical	Critical	NNP
cord-016871-1mlamf20	386	18	Care	Care	NNP
cord-016871-1mlamf20	386	19	Trials	Trials	NNPS
cord-016871-1mlamf20	386	20	Groups	Groups	NNPS
cord-016871-1mlamf20	386	21	.	.	.
cord-016871-1mlamf20	387	1	A	a	DT
cord-016871-1mlamf20	387	2	multicenter	multicenter	NN
cord-016871-1mlamf20	387	3	,	,	,
cord-016871-1mlamf20	387	4	randomized	randomized	JJ
cord-016871-1mlamf20	387	5	,	,	,
cord-016871-1mlamf20	387	6	controlled	control	VBN
cord-016871-1mlamf20	387	7	clinical	clinical	JJ
cord-016871-1mlamf20	387	8	trial	trial	NN
cord-016871-1mlamf20	387	9	of	of	IN
cord-016871-1mlamf20	387	10	transfusion	transfusion	NN
cord-016871-1mlamf20	387	11	requirements	requirement	NNS
cord-016871-1mlamf20	387	12	in	in	IN
cord-016871-1mlamf20	387	13	critical	critical	JJ
cord-016871-1mlamf20	387	14	care	care	NN
cord-016871-1mlamf20	387	15	Blood	blood	NN
cord-016871-1mlamf20	387	16	volume	volume	NN
cord-016871-1mlamf20	387	17	analysis	analysis	NN
cord-016871-1mlamf20	387	18	can	can	MD
cord-016871-1mlamf20	387	19	distinguish	distinguish	VB
cord-016871-1mlamf20	387	20	true	true	JJ
cord-016871-1mlamf20	387	21	anemia	anemia	NN
cord-016871-1mlamf20	387	22	from	from	IN
cord-016871-1mlamf20	387	23	hemodilution	hemodilution	NNP
cord-016871-1mlamf20	387	24	in	in	IN
cord-016871-1mlamf20	387	25	critically	critically	RB
cord-016871-1mlamf20	387	26	ill	ill	JJ
cord-016871-1mlamf20	387	27	patients	patient	NNS
cord-016871-1mlamf20	387	28	Anemia	anemia	NN
cord-016871-1mlamf20	387	29	in	in	IN
cord-016871-1mlamf20	387	30	the	the	DT
cord-016871-1mlamf20	387	31	long	long	JJ
cord-016871-1mlamf20	387	32	-	-	HYPH
cord-016871-1mlamf20	387	33	term	term	NN
cord-016871-1mlamf20	387	34	ventilator	ventilator	NN
cord-016871-1mlamf20	387	35	-	-	HYPH
cord-016871-1mlamf20	387	36	dependent	dependent	JJ
cord-016871-1mlamf20	387	37	patient	patient	NN
cord-016871-1mlamf20	387	38	with	with	IN
cord-016871-1mlamf20	387	39	respiratory	respiratory	JJ
cord-016871-1mlamf20	387	40	failure	failure	NN
cord-016871-1mlamf20	388	1	Pharmacokinetics	pharmacokinetic	NNS
cord-016871-1mlamf20	388	2	and	and	CC
cord-016871-1mlamf20	388	3	pharmacodynamics	pharmacodynamic	NNS
cord-016871-1mlamf20	388	4	of	of	IN
cord-016871-1mlamf20	388	5	once	once	RB
cord-016871-1mlamf20	388	6	-	-	HYPH
cord-016871-1mlamf20	388	7	weekly	weekly	NN
cord-016871-1mlamf20	388	8	subcutaneous	subcutaneous	JJ
cord-016871-1mlamf20	388	9	epoetin	epoetin	NNP
cord-016871-1mlamf20	388	10	alfa	alfa	NNP
cord-016871-1mlamf20	388	11	in	in	IN
cord-016871-1mlamf20	388	12	critically	critically	RB
cord-016871-1mlamf20	388	13	ill	ill	JJ
cord-016871-1mlamf20	388	14	patients	patient	NNS
cord-016871-1mlamf20	388	15	:	:	:
cord-016871-1mlamf20	388	16	results	result	NNS
cord-016871-1mlamf20	388	17	of	of	IN
cord-016871-1mlamf20	388	18	a	a	DT
cord-016871-1mlamf20	388	19	randomized	randomized	JJ
cord-016871-1mlamf20	388	20	,	,	,
cord-016871-1mlamf20	388	21	double	double	JJ
cord-016871-1mlamf20	388	22	-	-	HYPH
cord-016871-1mlamf20	388	23	blind	blind	JJ
cord-016871-1mlamf20	388	24	,	,	,
cord-016871-1mlamf20	388	25	placebo	placebo	NN
cord-016871-1mlamf20	388	26	-	-	HYPH
cord-016871-1mlamf20	388	27	controlled	control	VBN
cord-016871-1mlamf20	388	28	trial	trial	NN
cord-016871-1mlamf20	388	29	Prevalence	prevalence	NN
cord-016871-1mlamf20	388	30	and	and	CC
cord-016871-1mlamf20	388	31	outcomes	outcome	NNS
cord-016871-1mlamf20	388	32	of	of	IN
cord-016871-1mlamf20	388	33	anemia	anemia	NN
cord-016871-1mlamf20	388	34	in	in	IN
cord-016871-1mlamf20	388	35	cancer	cancer	NN
cord-016871-1mlamf20	388	36	:	:	:
cord-016871-1mlamf20	388	37	a	a	DT
cord-016871-1mlamf20	388	38	systematic	systematic	JJ
cord-016871-1mlamf20	388	39	review	review	NN
cord-016871-1mlamf20	388	40	of	of	IN
cord-016871-1mlamf20	388	41	the	the	DT
cord-016871-1mlamf20	388	42	literature	literature	NN
cord-016871-1mlamf20	388	43	For	for	IN
cord-016871-1mlamf20	388	44	the	the	DT
cord-016871-1mlamf20	388	45	EPO	EPO	NNP
cord-016871-1mlamf20	388	46	Critical	Critical	NNP
cord-016871-1mlamf20	388	47	Care	Care	NNP
cord-016871-1mlamf20	388	48	Trials	Trials	NNPS
cord-016871-1mlamf20	388	49	Group	Group	NNP
cord-016871-1mlamf20	388	50	.	.	.
cord-016871-1mlamf20	389	1	Ef	Ef	NNP
cord-016871-1mlamf20	389	2	fi	fi	NN
cord-016871-1mlamf20	389	3	cacy	cacy	NN
cord-016871-1mlamf20	389	4	and	and	CC
cord-016871-1mlamf20	389	5	safety	safety	NN
cord-016871-1mlamf20	389	6	of	of	IN
cord-016871-1mlamf20	389	7	epoetin	epoetin	NNP
cord-016871-1mlamf20	389	8	alfa	alfa	NNP
cord-016871-1mlamf20	389	9	in	in	IN
cord-016871-1mlamf20	389	10	critically	critically	RB
cord-016871-1mlamf20	389	11	ill	ill	JJ
cord-016871-1mlamf20	389	12	patients	patient	NNS
cord-016871-1mlamf20	390	1	Randomized	randomized	JJ
cord-016871-1mlamf20	390	2	clinical	clinical	JJ
cord-016871-1mlamf20	390	3	trial	trial	NN
cord-016871-1mlamf20	390	4	of	of	IN
cord-016871-1mlamf20	390	5	preoperative	preoperative	JJ
cord-016871-1mlamf20	390	6	intravenous	intravenous	JJ
cord-016871-1mlamf20	390	7	iron	iron	NN
cord-016871-1mlamf20	390	8	sucrose	sucrose	NN
cord-016871-1mlamf20	390	9	to	to	TO
cord-016871-1mlamf20	390	10	reduce	reduce	VB
cord-016871-1mlamf20	390	11	blood	blood	NN
cord-016871-1mlamf20	390	12	transfusion	transfusion	NN
cord-016871-1mlamf20	390	13	in	in	IN
cord-016871-1mlamf20	390	14	anaemic	anaemic	JJ
cord-016871-1mlamf20	390	15	patients	patient	NNS
cord-016871-1mlamf20	390	16	after	after	IN
cord-016871-1mlamf20	390	17	colorectal	colorectal	JJ
cord-016871-1mlamf20	390	18	cancer	cancer	NN
cord-016871-1mlamf20	390	19	surgery	surgery	NN
cord-016871-1mlamf20	391	1	The	the	DT
cord-016871-1mlamf20	391	2	effect	effect	NN
cord-016871-1mlamf20	391	3	of	of	IN
cord-016871-1mlamf20	391	4	plasma	plasma	NN
cord-016871-1mlamf20	391	5	transfusion	transfusion	NN
cord-016871-1mlamf20	391	6	on	on	IN
cord-016871-1mlamf20	391	7	morbidity	morbidity	NN
cord-016871-1mlamf20	391	8	and	and	CC
cord-016871-1mlamf20	391	9	mortality	mortality	NN
cord-016871-1mlamf20	391	10	:	:	:
cord-016871-1mlamf20	391	11	a	a	DT
cord-016871-1mlamf20	391	12	systematic	systematic	JJ
cord-016871-1mlamf20	391	13	review	review	NN
cord-016871-1mlamf20	391	14	and	and	CC
cord-016871-1mlamf20	391	15	meta	meta	NNP
cord-016871-1mlamf20	391	16	-	-	HYPH
cord-016871-1mlamf20	391	17	analysis	analysis	NN
cord-016871-1mlamf20	391	18	Risks	risk	NNS
cord-016871-1mlamf20	391	19	of	of	IN
cord-016871-1mlamf20	391	20	fresh	fresh	JJ
cord-016871-1mlamf20	391	21	frozen	frozen	JJ
cord-016871-1mlamf20	391	22	plasma	plasma	NN
cord-016871-1mlamf20	391	23	and	and	CC
cord-016871-1mlamf20	391	24	platelets	platelet	NNS
cord-016871-1mlamf20	391	25	Appropriateness	appropriateness	NN
cord-016871-1mlamf20	391	26	of	of	IN
cord-016871-1mlamf20	391	27	fresh	fresh	JJ
cord-016871-1mlamf20	391	28	-	-	HYPH
cord-016871-1mlamf20	391	29	frozen	frozen	JJ
cord-016871-1mlamf20	391	30	plasma	plasma	NN
cord-016871-1mlamf20	391	31	usage	usage	NN
cord-016871-1mlamf20	391	32	in	in	IN
cord-016871-1mlamf20	391	33	hospital	hospital	NN
cord-016871-1mlamf20	391	34	settings	setting	NNS
cord-016871-1mlamf20	391	35	:	:	:
cord-016871-1mlamf20	391	36	a	a	DT
cord-016871-1mlamf20	391	37	meta	meta	JJ
cord-016871-1mlamf20	391	38	-	-	HYPH
cord-016871-1mlamf20	391	39	analysis	analysis	NN
cord-016871-1mlamf20	391	40	of	of	IN
cord-016871-1mlamf20	391	41	the	the	DT
cord-016871-1mlamf20	391	42	impact	impact	NN
cord-016871-1mlamf20	391	43	of	of	IN
cord-016871-1mlamf20	391	44	organizational	organizational	JJ
cord-016871-1mlamf20	391	45	intervations	intervation	NNS
cord-016871-1mlamf20	391	46	Utilisation	Utilisation	NNP
cord-016871-1mlamf20	391	47	de	de	IN
cord-016871-1mlamf20	391	48	plasma	plasma	NN
cord-016871-1mlamf20	391	49	:	:	:
cord-016871-1mlamf20	391	50	indications	indication	NNS
cord-016871-1mlamf20	391	51	médicales	médicales	NNP
cord-016871-1mlamf20	391	52	et	et	NNP
cord-016871-1mlamf20	391	53	préparation	préparation	FW
cord-016871-1mlamf20	391	54	de	de	FW
cord-016871-1mlamf20	391	55	plasma	plasma	NN
cord-016871-1mlamf20	391	56	en	en	NNP
cord-016871-1mlamf20	391	57	Suède	Suède	NNP
cord-016871-1mlamf20	391	58	[	[	-LRB-
cord-016871-1mlamf20	391	59	Use	use	NN
cord-016871-1mlamf20	391	60	of	of	IN
cord-016871-1mlamf20	391	61	plasma	plasma	NN
cord-016871-1mlamf20	391	62	:	:	:
cord-016871-1mlamf20	391	63	clinical	clinical	JJ
cord-016871-1mlamf20	391	64	indications	indication	NNS
cord-016871-1mlamf20	391	65	and	and	CC
cord-016871-1mlamf20	391	66	types	type	NNS
cord-016871-1mlamf20	391	67	of	of	IN
cord-016871-1mlamf20	391	68	plasma	plasma	NN
cord-016871-1mlamf20	391	69	components	component	NNS
cord-016871-1mlamf20	391	70	in	in	IN
cord-016871-1mlamf20	391	71	Sweden	Sweden	NNP
cord-016871-1mlamf20	391	72	Management	Management	NNP
cord-016871-1mlamf20	391	73	of	of	IN
cord-016871-1mlamf20	391	74	post	post	JJ
cord-016871-1mlamf20	391	75	-	-	JJ
cord-016871-1mlamf20	391	76	partum	partum	JJ
cord-016871-1mlamf20	391	77	haemorrhage	haemorrhage	NN
cord-016871-1mlamf20	392	1	Ef	Ef	NNP
cord-016871-1mlamf20	392	2	fi	fi	NNP
cord-016871-1mlamf20	392	3	cacy	cacy	NN
cord-016871-1mlamf20	392	4	evaluation	evaluation	NN
cord-016871-1mlamf20	392	5	of	of	IN
cord-016871-1mlamf20	392	6	current	current	JJ
cord-016871-1mlamf20	392	7	and	and	CC
cord-016871-1mlamf20	392	8	future	future	JJ
cord-016871-1mlamf20	392	9	platelet	platelet	NN
cord-016871-1mlamf20	392	10	transfusion	transfusion	NN
cord-016871-1mlamf20	392	11	products	product	NNS
cord-016871-1mlamf20	392	12	Whole	whole	JJ
cord-016871-1mlamf20	392	13	blood	blood	NN
cord-016871-1mlamf20	392	14	transfusion	transfusion	NN
cord-016871-1mlamf20	392	15	for	for	IN
cord-016871-1mlamf20	392	16	exsanguinating	exsanguinate	VBG
cord-016871-1mlamf20	392	17	coagulopathy	coagulopathy	NN
cord-016871-1mlamf20	392	18	in	in	IN
cord-016871-1mlamf20	392	19	a	a	DT
cord-016871-1mlamf20	392	20	U.S.	U.S.	NNP
cord-016871-1mlamf20	392	21	fi	fi	NN
cord-016871-1mlamf20	392	22	eld	eld	NNP
cord-016871-1mlamf20	392	23	surgical	surgical	JJ
cord-016871-1mlamf20	392	24	hospital	hospital	NN
cord-016871-1mlamf20	392	25	in	in	IN
cord-016871-1mlamf20	392	26	postwar	postwar	JJ
cord-016871-1mlamf20	392	27	Kosovo	Kosovo	NNP
cord-016871-1mlamf20	392	28	Recombinant	Recombinant	NNP
cord-016871-1mlamf20	392	29	activated	activate	VBN
cord-016871-1mlamf20	392	30	factor	factor	NN
cord-016871-1mlamf20	393	1	VII	VII	NNP
cord-016871-1mlamf20	393	2	(	(	-LRB-
cord-016871-1mlamf20	393	3	NovoSeven	NovoSeven	NNP
cord-016871-1mlamf20	393	4	)	)	-RRB-
cord-016871-1mlamf20	394	1	:	:	:
cord-016871-1mlamf20	394	2	addition	addition	NN
cord-016871-1mlamf20	394	3	to	to	IN
cord-016871-1mlamf20	394	4	replacement	replacement	NN
cord-016871-1mlamf20	394	5	therapy	therapy	NN
cord-016871-1mlamf20	394	6	in	in	IN
cord-016871-1mlamf20	394	7	acute	acute	JJ
cord-016871-1mlamf20	394	8	,	,	,
cord-016871-1mlamf20	394	9	uncontrolled	uncontrolled	JJ
cord-016871-1mlamf20	394	10	and	and	CC
cord-016871-1mlamf20	394	11	life	life	NN
cord-016871-1mlamf20	394	12	-	-	HYPH
cord-016871-1mlamf20	394	13	threatening	threaten	VBG
cord-016871-1mlamf20	394	14	bleeding	bleed	VBG
cord-016871-1mlamf20	394	15	Blood	blood	NN
cord-016871-1mlamf20	394	16	transfusions	transfusion	NNS
cord-016871-1mlamf20	394	17	,	,	,
cord-016871-1mlamf20	394	18	thrombosis	thrombosis	NN
cord-016871-1mlamf20	394	19	,	,	,
cord-016871-1mlamf20	394	20	and	and	CC
cord-016871-1mlamf20	394	21	mortality	mortality	NN
cord-016871-1mlamf20	394	22	in	in	IN
cord-016871-1mlamf20	394	23	hospitalized	hospitalize	VBN
cord-016871-1mlamf20	394	24	patients	patient	NNS
cord-016871-1mlamf20	394	25	with	with	IN
cord-016871-1mlamf20	394	26	cancer	cancer	NN
cord-016871-1mlamf20	394	27	Transfusion	transfusion	NN
cord-016871-1mlamf20	394	28	-	-	HYPH
cord-016871-1mlamf20	394	29	related	relate	VBN
cord-016871-1mlamf20	394	30	acute	acute	JJ
cord-016871-1mlamf20	394	31	lung	lung	NN
cord-016871-1mlamf20	394	32	injury	injury	NN
cord-016871-1mlamf20	394	33	(	(	-LRB-
cord-016871-1mlamf20	394	34	TRALI	TRALI	NNP
cord-016871-1mlamf20	394	35	)	)	-RRB-
cord-016871-1mlamf20	394	36	:	:	:
cord-016871-1mlamf20	394	37	current	current	JJ
cord-016871-1mlamf20	394	38	concepts	concept	NNS
cord-016871-1mlamf20	394	39	and	and	CC
cord-016871-1mlamf20	394	40	misconceptions	misconception	NNS
cord-016871-1mlamf20	394	41	Effective	effective	JJ
cord-016871-1mlamf20	394	42	reduction	reduction	NN
cord-016871-1mlamf20	394	43	of	of	IN
cord-016871-1mlamf20	394	44	transfusion	transfusion	NN
cord-016871-1mlamf20	394	45	-	-	HYPH
cord-016871-1mlamf20	394	46	related	relate	VBN
cord-016871-1mlamf20	394	47	acute	acute	JJ
cord-016871-1mlamf20	394	48	lung	lung	NN
cord-016871-1mlamf20	394	49	injury	injury	NN
cord-016871-1mlamf20	394	50	risk	risk	NN
cord-016871-1mlamf20	394	51	with	with	IN
cord-016871-1mlamf20	394	52	male	male	JJ
cord-016871-1mlamf20	394	53	-	-	HYPH
cord-016871-1mlamf20	394	54	predominant	predominant	JJ
cord-016871-1mlamf20	394	55	plasma	plasma	NN
cord-016871-1mlamf20	394	56	strategy	strategy	NN
cord-016871-1mlamf20	394	57	in	in	IN
cord-016871-1mlamf20	394	58	the	the	DT
cord-016871-1mlamf20	394	59	American	American	NNP
cord-016871-1mlamf20	394	60	Red	Red	NNP
cord-016871-1mlamf20	394	61	Cross	Cross	NNP
cord-016871-1mlamf20	394	62	Cumulative	cumulative	JJ
cord-016871-1mlamf20	394	63	risks	risk	NNS
cord-016871-1mlamf20	394	64	of	of	IN
cord-016871-1mlamf20	394	65	early	early	JJ
cord-016871-1mlamf20	394	66	red	red	JJ
cord-016871-1mlamf20	394	67	blood	blood	NN
cord-016871-1mlamf20	394	68	cell	cell	NN
cord-016871-1mlamf20	394	69	transfusion	transfusion	NN
cord-016871-1mlamf20	395	1	In	in	IN
cord-016871-1mlamf20	395	2	fl	fl	NNP
cord-016871-1mlamf20	395	3	ammation	ammation	NN
cord-016871-1mlamf20	395	4	and	and	CC
cord-016871-1mlamf20	395	5	the	the	DT
cord-016871-1mlamf20	395	6	Host	Host	NNP
cord-016871-1mlamf20	395	7	Response	response	NN
cord-016871-1mlamf20	395	8	to	to	IN
cord-016871-1mlamf20	395	9	Injury	injury	NN
cord-016871-1mlamf20	395	10	Investigators	investigator	NNS
cord-016871-1mlamf20	395	11	.	.	.
cord-016871-1mlamf20	396	1	Fresh	fresh	JJ
cord-016871-1mlamf20	396	2	frozen	frozen	JJ
cord-016871-1mlamf20	396	3	plasma	plasma	NN
cord-016871-1mlamf20	396	4	is	be	VBZ
cord-016871-1mlamf20	396	5	independently	independently	RB
cord-016871-1mlamf20	396	6	associated	associate	VBN
cord-016871-1mlamf20	396	7	with	with	IN
cord-016871-1mlamf20	396	8	a	a	DT
cord-016871-1mlamf20	396	9	higher	high	JJR
cord-016871-1mlamf20	396	10	risk	risk	NN
cord-016871-1mlamf20	396	11	of	of	IN
cord-016871-1mlamf20	396	12	multiple	multiple	JJ
cord-016871-1mlamf20	396	13	organ	organ	NN
cord-016871-1mlamf20	396	14	failure	failure	NN
cord-016871-1mlamf20	396	15	and	and	CC
cord-016871-1mlamf20	396	16	acute	acute	JJ
cord-016871-1mlamf20	396	17	respiratory	respiratory	JJ
cord-016871-1mlamf20	396	18	distress	distress	NN
cord-016871-1mlamf20	396	19	syndrome	syndrome	NN
cord-016871-1mlamf20	397	1	A	a	DT
cord-016871-1mlamf20	397	2	prospective	prospective	JJ
cord-016871-1mlamf20	397	3	,	,	,
cord-016871-1mlamf20	397	4	double	double	JJ
cord-016871-1mlamf20	397	5	-	-	HYPH
cord-016871-1mlamf20	397	6	blind	blind	JJ
cord-016871-1mlamf20	397	7	,	,	,
cord-016871-1mlamf20	397	8	randomized	randomized	JJ
cord-016871-1mlamf20	397	9	clinical	clinical	JJ
cord-016871-1mlamf20	397	10	feasibility	feasibility	NN
cord-016871-1mlamf20	397	11	trial	trial	NN
cord-016871-1mlamf20	397	12	of	of	IN
cord-016871-1mlamf20	397	13	controlling	control	VBG
cord-016871-1mlamf20	397	14	the	the	DT
cord-016871-1mlamf20	397	15	storage	storage	NN
cord-016871-1mlamf20	397	16	age	age	NN
cord-016871-1mlamf20	397	17	of	of	IN
cord-016871-1mlamf20	397	18	red	red	JJ
cord-016871-1mlamf20	397	19	blood	blood	NN
cord-016871-1mlamf20	397	20	cells	cell	NNS
cord-016871-1mlamf20	397	21	for	for	IN
cord-016871-1mlamf20	397	22	transfusion	transfusion	NN
cord-016871-1mlamf20	397	23	in	in	IN
cord-016871-1mlamf20	397	24	cardiac	cardiac	JJ
cord-016871-1mlamf20	397	25	surgical	surgical	JJ
cord-016871-1mlamf20	397	26	patients	patient	NNS
cord-016871-1mlamf20	397	27	Prospective	prospective	JJ
cord-016871-1mlamf20	397	28	monitoring	monitoring	NN
cord-016871-1mlamf20	397	29	of	of	IN
cord-016871-1mlamf20	397	30	plasma	plasma	NN
cord-016871-1mlamf20	397	31	and	and	CC
cord-016871-1mlamf20	397	32	platelet	platelet	NN
cord-016871-1mlamf20	397	33	transfusions	transfusion	NNS
cord-016871-1mlamf20	397	34	in	in	IN
cord-016871-1mlamf20	397	35	a	a	DT
cord-016871-1mlamf20	397	36	large	large	JJ
cord-016871-1mlamf20	397	37	teaching	teaching	NN
cord-016871-1mlamf20	397	38	hospital	hospital	NN
cord-016871-1mlamf20	397	39	results	result	NNS
cord-016871-1mlamf20	397	40	in	in	IN
cord-016871-1mlamf20	397	41	signi	signi	NNP
cord-016871-1mlamf20	397	42	fi	fi	NNP
cord-016871-1mlamf20	397	43	ca	can	MD
cord-016871-1mlamf20	397	44	nt	not	RB
cord-016871-1mlamf20	397	45	cost	cost	VB
cord-016871-1mlamf20	397	46	reduction	reduction	NN
cord-016871-1mlamf20	397	47	Emergency	emergency	NN
cord-016871-1mlamf20	397	48	transfusion	transfusion	NN
cord-016871-1mlamf20	397	49	score	score	NN
cord-016871-1mlamf20	397	50	(	(	-LRB-
cord-016871-1mlamf20	397	51	ETS	ETS	NNP
cord-016871-1mlamf20	397	52	)	)	-RRB-
cord-016871-1mlamf20	397	53	:	:	:
cord-016871-1mlamf20	398	1	a	a	DT
cord-016871-1mlamf20	398	2	useful	useful	JJ
cord-016871-1mlamf20	398	3	instrument	instrument	NN
cord-016871-1mlamf20	398	4	for	for	IN
cord-016871-1mlamf20	398	5	prediction	prediction	NN
cord-016871-1mlamf20	398	6	of	of	IN
cord-016871-1mlamf20	398	7	blood	blood	NN
cord-016871-1mlamf20	398	8	transfusion	transfusion	NN
cord-016871-1mlamf20	398	9	requirement	requirement	NN
cord-016871-1mlamf20	398	10	in	in	IN
cord-016871-1mlamf20	398	11	severely	severely	RB
cord-016871-1mlamf20	398	12	injured	injure	VBN
cord-016871-1mlamf20	398	13	patients	patient	NNS
cord-016871-1mlamf20	398	14	Management	Management	NNP
cord-016871-1mlamf20	398	15	of	of	IN
cord-016871-1mlamf20	398	16	surgical	surgical	JJ
cord-016871-1mlamf20	398	17	patients	patient	NNS
cord-016871-1mlamf20	398	18	receiving	receive	VBG
cord-016871-1mlamf20	398	19	anticoagulation	anticoagulation	NN
cord-016871-1mlamf20	398	20	and	and	CC
cord-016871-1mlamf20	398	21	antiplatelet	antiplatelet	NN
cord-016871-1mlamf20	398	22	agents	agent	NNS
cord-016871-1mlamf20	398	23	Critical	critical	JJ
cord-016871-1mlamf20	398	24	care	care	NN
cord-016871-1mlamf20	398	25	obstetrics	obstetric	NNS
cord-016871-1mlamf20	398	26	and	and	CC
cord-016871-1mlamf20	398	27	gynecology	gynecology	NN
cord-016871-1mlamf20	398	28	Treatment	Treatment	NNP
cord-016871-1mlamf20	398	29	of	of	IN
cord-016871-1mlamf20	398	30	obstetric	obstetric	JJ
cord-016871-1mlamf20	398	31	hemorrhage	hemorrhage	NN
cord-016871-1mlamf20	398	32	with	with	IN
cord-016871-1mlamf20	398	33	recombinant	recombinant	JJ
cord-016871-1mlamf20	398	34	activated	activate	VBN
cord-016871-1mlamf20	398	35	factor	factor	NN
cord-016871-1mlamf20	398	36	VII	VII	NNP
cord-016871-1mlamf20	398	37	(	(	-LRB-
cord-016871-1mlamf20	398	38	rFVIIa	rfviia	NN
cord-016871-1mlamf20	398	39	)	)	-RRB-
cord-016871-1mlamf20	399	1	Peres	Peres	NNP
cord-016871-1mlamf20	399	2	-	-	HYPH
cord-016871-1mlamf20	399	3	Bota	Bota	NNP
cord-016871-1mlamf20	399	4	D	D	NNP
cord-016871-1mlamf20	399	5	,	,	,
cord-016871-1mlamf20	399	6	the	the	DT
cord-016871-1mlamf20	399	7	ABC	ABC	NNP
cord-016871-1mlamf20	399	8	Investigators	Investigators	NNPS
cord-016871-1mlamf20	399	9	.	.	.
cord-016871-1mlamf20	400	1	Anemia	anemia	NN
cord-016871-1mlamf20	400	2	and	and	CC
cord-016871-1mlamf20	400	3	blood	blood	NN
cord-016871-1mlamf20	400	4	transfusion	transfusion	NN
cord-016871-1mlamf20	400	5	in	in	IN
cord-016871-1mlamf20	400	6	critically	critically	RB
cord-016871-1mlamf20	400	7	ill	ill	JJ
cord-016871-1mlamf20	400	8	patients	patient	NNS
cord-016871-1mlamf20	400	9	All	all	DT
cord-016871-1mlamf20	400	10	bleeding	bleed	VBG
cord-016871-1mlamf20	400	11	stops	stop	VBZ
cord-016871-1mlamf20	400	12	:	:	:
cord-016871-1mlamf20	400	13	how	how	WRB
cord-016871-1mlamf20	400	14	we	-PRON-	PRP
cord-016871-1mlamf20	400	15	can	can	MD
cord-016871-1mlamf20	400	16	help	help	VB
cord-016871-1mlamf20	400	17	…	…	NFP
cord-016871-1mlamf20	401	1	Rapid	rapid	JJ
cord-016871-1mlamf20	401	2	thromboelastography	thromboelastography	NNP
cord-016871-1mlamf20	401	3	delivers	deliver	VBZ
cord-016871-1mlamf20	401	4	realtime	realtime	JJ
cord-016871-1mlamf20	401	5	results	result	NNS
cord-016871-1mlamf20	401	6	that	that	WDT
cord-016871-1mlamf20	401	7	predict	predict	VBP
cord-016871-1mlamf20	401	8	transfusion	transfusion	NN
cord-016871-1mlamf20	401	9	within	within	IN
cord-016871-1mlamf20	401	10	1	1	CD
cord-016871-1mlamf20	401	11	hour	hour	NN
cord-016871-1mlamf20	401	12	of	of	IN
cord-016871-1mlamf20	401	13	admission	admission	NN
cord-016871-1mlamf20	401	14	Quantitative	quantitative	JJ
cord-016871-1mlamf20	401	15	measurement	measurement	NN
cord-016871-1mlamf20	401	16	of	of	IN
cord-016871-1mlamf20	401	17	thromboelastography	thromboelastography	NNP
cord-016871-1mlamf20	401	18	as	as	IN
cord-016871-1mlamf20	401	19	a	a	DT
cord-016871-1mlamf20	401	20	function	function	NN
cord-016871-1mlamf20	401	21	of	of	IN
cord-016871-1mlamf20	401	22	platelet	platelet	NN
cord-016871-1mlamf20	401	23	count	count	NN
cord-016871-1mlamf20	401	24	A	a	DT
cord-016871-1mlamf20	401	25	comparative	comparative	JJ
cord-016871-1mlamf20	401	26	evaluation	evaluation	NN
cord-016871-1mlamf20	401	27	of	of	IN
cord-016871-1mlamf20	401	28	rotation	rotation	NN
cord-016871-1mlamf20	401	29	thromboelastometry	thromboelastometry	NN
cord-016871-1mlamf20	401	30	and	and	CC
cord-016871-1mlamf20	401	31	standard	standard	JJ
cord-016871-1mlamf20	401	32	coagulation	coagulation	NN
cord-016871-1mlamf20	401	33	tests	test	NNS
cord-016871-1mlamf20	401	34	in	in	IN
cord-016871-1mlamf20	401	35	hemodilution	hemodilution	NN
cord-016871-1mlamf20	401	36	-	-	HYPH
cord-016871-1mlamf20	401	37	induced	induce	VBN
cord-016871-1mlamf20	401	38	coagulation	coagulation	NN
cord-016871-1mlamf20	401	39	changes	change	NNS
cord-016871-1mlamf20	401	40	after	after	IN
cord-016871-1mlamf20	401	41	cardiac	cardiac	JJ
cord-016871-1mlamf20	401	42	surgery	surgery	NN
cord-016871-1mlamf20	402	1	A	a	DT
cord-016871-1mlamf20	402	2	comparison	comparison	NN
cord-016871-1mlamf20	402	3	of	of	IN
cord-016871-1mlamf20	402	4	fi	fi	NNP
cord-016871-1mlamf20	402	5	brinogen	brinogen	NNP
cord-016871-1mlamf20	402	6	measurement	measurement	NN
cord-016871-1mlamf20	402	7	methods	method	NNS
cord-016871-1mlamf20	402	8	with	with	IN
cord-016871-1mlamf20	402	9	fi	fi	NNP
cord-016871-1mlamf20	402	10	brin	brin	NNP
cord-016871-1mlamf20	402	11	clot	clot	NN
cord-016871-1mlamf20	402	12	elasticity	elasticity	NN
cord-016871-1mlamf20	402	13	assessed	assess	VBN
cord-016871-1mlamf20	402	14	by	by	IN
cord-016871-1mlamf20	402	15	thromboelastometry	thromboelastometry	NNP
cord-016871-1mlamf20	402	16	,	,	,
cord-016871-1mlamf20	402	17	before	before	IN
cord-016871-1mlamf20	402	18	and	and	CC
cord-016871-1mlamf20	402	19	after	after	IN
cord-016871-1mlamf20	402	20	administration	administration	NN
cord-016871-1mlamf20	402	21	of	of	IN
cord-016871-1mlamf20	402	22	fi	fi	NNP
cord-016871-1mlamf20	402	23	brinogen	brinogen	NNP
cord-016871-1mlamf20	402	24	concentrate	concentrate	VBP
cord-016871-1mlamf20	402	25	in	in	IN
cord-016871-1mlamf20	402	26	cardiac	cardiac	JJ
cord-016871-1mlamf20	402	27	surgery	surgery	NN
cord-016871-1mlamf20	402	28	patients	patient	NNS
cord-016871-1mlamf20	402	29	Can	Can	MD
cord-016871-1mlamf20	402	30	the	the	DT
cord-016871-1mlamf20	402	31	use	use	NN
cord-016871-1mlamf20	402	32	of	of	IN
cord-016871-1mlamf20	402	33	thromboelastography	thromboelastography	NNP
cord-016871-1mlamf20	402	34	predict	predict	VBP
cord-016871-1mlamf20	402	35	and	and	CC
cord-016871-1mlamf20	402	36	decrease	decrease	VB
cord-016871-1mlamf20	402	37	bleeding	bleeding	NN
cord-016871-1mlamf20	402	38	and	and	CC
cord-016871-1mlamf20	402	39	blood	blood	NN
cord-016871-1mlamf20	402	40	and	and	CC
cord-016871-1mlamf20	402	41	blood	blood	NN
cord-016871-1mlamf20	402	42	product	product	NN
cord-016871-1mlamf20	402	43	requirements	requirement	NNS
cord-016871-1mlamf20	402	44	in	in	IN
cord-016871-1mlamf20	402	45	adult	adult	NN
cord-016871-1mlamf20	402	46	patients	patient	NNS
cord-016871-1mlamf20	402	47	undergoing	undergo	VBG
cord-016871-1mlamf20	402	48	cardiac	cardiac	JJ
cord-016871-1mlamf20	402	49	surgery	surgery	NN
cord-016871-1mlamf20	402	50	?	?	.
cord-016871-1mlamf20	403	1	Hemostatic	hemostatic	JJ
cord-016871-1mlamf20	403	2	changes	change	NNS
cord-016871-1mlamf20	403	3	after	after	IN
cord-016871-1mlamf20	403	4	crystalloid	crystalloid	NNP
cord-016871-1mlamf20	403	5	or	or	CC
cord-016871-1mlamf20	403	6	colloid	colloid	NNP
cord-016871-1mlamf20	403	7	fl	fl	NNP
cord-016871-1mlamf20	403	8	uid	uid	NNP
cord-016871-1mlamf20	403	9	administration	administration	NN
cord-016871-1mlamf20	403	10	during	during	IN
cord-016871-1mlamf20	403	11	major	major	JJ
cord-016871-1mlamf20	403	12	orthopedic	orthopedic	NN
cord-016871-1mlamf20	403	13	surgery	surgery	NN
cord-016871-1mlamf20	403	14	:	:	:
cord-016871-1mlamf20	404	1	the	the	DT
cord-016871-1mlamf20	404	2	role	role	NN
cord-016871-1mlamf20	404	3	of	of	IN
cord-016871-1mlamf20	404	4	fi	fi	NNP
cord-016871-1mlamf20	404	5	brinogen	brinogen	NNP
cord-016871-1mlamf20	404	6	administration	administration	NNP
cord-016871-1mlamf20	404	7	Point	Point	NNP
cord-016871-1mlamf20	404	8	-	-	HYPH
cord-016871-1mlamf20	404	9	of	of	IN
cord-016871-1mlamf20	404	10	-	-	HYPH
cord-016871-1mlamf20	404	11	care	care	NN
cord-016871-1mlamf20	404	12	platelet	platelet	NN
cord-016871-1mlamf20	404	13	function	function	NN
cord-016871-1mlamf20	404	14	tests	test	NNS
cord-016871-1mlamf20	404	15	:	:	:
cord-016871-1mlamf20	404	16	detection	detection	NN
cord-016871-1mlamf20	404	17	of	of	IN
cord-016871-1mlamf20	404	18	platelet	platelet	NN
cord-016871-1mlamf20	404	19	inhibition	inhibition	NN
cord-016871-1mlamf20	404	20	induced	induce	VBN
cord-016871-1mlamf20	404	21	by	by	IN
cord-016871-1mlamf20	404	22	nonopioid	nonopioid	NNP
cord-016871-1mlamf20	404	23	analgesic	analgesic	JJ
cord-016871-1mlamf20	404	24	drugs	drug	NNS
cord-016871-1mlamf20	404	25	Thromboelastography	Thromboelastography	NNP
cord-016871-1mlamf20	404	26	:	:	:
cord-016871-1mlamf20	404	27	theory	theory	NN
cord-016871-1mlamf20	404	28	and	and	CC
cord-016871-1mlamf20	404	29	practice	practice	NN
cord-016871-1mlamf20	404	30	in	in	IN
cord-016871-1mlamf20	404	31	measuring	measure	VBG
cord-016871-1mlamf20	404	32	hemostasis	hemostasis	NN
cord-016871-1mlamf20	404	33	Admission	admission	NN
cord-016871-1mlamf20	404	34	rapid	rapid	JJ
cord-016871-1mlamf20	404	35	thrombelastography	thrombelastography	NN
cord-016871-1mlamf20	404	36	(	(	-LRB-
cord-016871-1mlamf20	404	37	r	r	NNP
cord-016871-1mlamf20	404	38	-	-	HYPH
cord-016871-1mlamf20	404	39	TEG	TEG	NNP
cord-016871-1mlamf20	404	40	)	)	-RRB-
cord-016871-1mlamf20	404	41	can	can	MD
cord-016871-1mlamf20	404	42	replace	replace	VB
cord-016871-1mlamf20	404	43	conventional	conventional	JJ
cord-016871-1mlamf20	404	44	coagulation	coagulation	NN
cord-016871-1mlamf20	404	45	tests	test	NNS
cord-016871-1mlamf20	404	46	in	in	IN
cord-016871-1mlamf20	404	47	the	the	DT
cord-016871-1mlamf20	404	48	emergency	emergency	NN
cord-016871-1mlamf20	404	49	department	department	NN
cord-016871-1mlamf20	404	50	:	:	:
cord-016871-1mlamf20	404	51	experience	experience	NN
cord-016871-1mlamf20	404	52	with	with	IN
cord-016871-1mlamf20	404	53	1974	1974	CD
cord-016871-1mlamf20	404	54	consecutive	consecutive	JJ
cord-016871-1mlamf20	404	55	trauma	trauma	NN
cord-016871-1mlamf20	404	56	patients	patient	NNS