id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-022474-xxy83c6u	Tenorio, Grace C.	Transfusion Medicine and Immunohematology	2007		.txt	text/plain	12087	627	44	Current blood separators can collect granulocytes at high yields (20 to 30 10 9 granulocytes) from donors stimulated with recombinant granulocyte colonystimulating factor (G-CSF) and steroids; however, granulocyte transfusions lost popularity between 1985 and 1995 because of reported adverse pulmonary reactions and marginal clinical results. Patients with Chido (Ch) and Rogers (Rg) antibodies (against the Ch/Rg blood group antigens carried by complement C4d of the classic complement pathway) also exhibit anaphylactoid reactions following plasma product transfusions. Major strategies available to reduce transmission include: stringent donor selection and laboratory testing; use of autologous blood, pharmacological substitutes, or new transfusion strategies; inactivation of residual infectious agents in the units to be transfused, and limiting the number of donor exposures and allogeneic transfusions. HIV is transmitted by both cellular blood components and plasma; however, both types of HTLV are highly cell-associated and require viable lymphocytes for transfusion transmission. Despite transfusions of "CMV-reduced-risk blood components," a few marrow transplant patients (1 to 4%) still develop primary CMV infection.	./cache/cord-022474-xxy83c6u.txt	./txt/cord-022474-xxy83c6u.txt