id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017946-fa4ehlb0	Lawless, Ryan A.	Adjuncts to Resuscitation	2018-05-26		.txt	text/plain	5937	298	36	This chapter will focus on adjuncts to damage control resuscitation (DCR) including massive transfusion protocols, the "other" tenets of damage control resuscitation, hypertonic saline, tranexamic acid, pharmacologic resuscitation, Factor VIIa, and prothrombin complex, and viscoelastic testing. Looking at the incorporation of the other two principles (permissive hypotension and minimizing crystalloids) into a mature trauma center already incorporating a transfusion strategy approaching whole blood, investigators found an improvement in survival among emergent laparotomy patients [4] . The authors noted a significantly improved mortality compared to that predicted by the Trauma Related Injury Severity Score (TRISS) in patients who received fibrinogen concentrate during their initial resuscitation. Animal models of liver injury associated hemorrhagic shock have shown decreased blood loss, increased mean arterial pressure, and significantly higher hemoglobin levels with vasopressin administration compared to standard crystalloid resuscitation [74] . A randomized, placebo-controlled study (AVERT Shock) is currently underway to investigate the potential benefit of vasopressin administration during the early resuscitation of bleeding trauma patients [79].	./cache/cord-017946-fa4ehlb0.txt	./txt/cord-017946-fa4ehlb0.txt