id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-355623-tmr1ieg1	Gallucci, Marcella	When the Cough Does Not Improve: A Review on Protracted Bacterial Bronchitis in Children	2020-08-07		.txt	text/plain	4318	200	41	Protracted bacterial bronchitis (PBB) is a common cause of chronic wet cough in preschool children with no symptoms or signs of other specific causes, and resolution usually follows a 2-week course of an appropriate oral antibiotic. in an Australian study among children with a history of chronic wet cough lasting more than 4 weeks, a positive culture of a respiratory pathogen on BAL (bacterial growth ≥10 4 CFU/ml in BAL) obtained during a flexible bronchoscopy and a clinical response to 2 weeks treatment with antibiotics (amoxicillinclavulanate acid) (9) ( Table 1) . According to the European Respiratory Society (ERS) guidelines new definition, PBB-clinical is based on all three of the following criteria: "presence of chronic (>4 weeks' duration) wet or productive cough; absence of symptoms or signs (i.e., specific cough pointers) suggestive of other causes of wet or productive Abbreviations: BA, bronchial aspirate; BAL, bronchoalveolar lavage; CLDS, cystic lung diseases; CT, computerized tomography; GER, gastroesophageal reflux; NTHi, Haemophilus influenzae non-typeable; PBB, protracted bacterial bronchitis; QoL, quality of life; UACS, upper airway cough syndrome.	./cache/cord-355623-tmr1ieg1.txt	./txt/cord-355623-tmr1ieg1.txt