id sid tid token lemma pos cord-327287-e5k2gcse 1 1 key key JJ cord-327287-e5k2gcse 1 2 : : : cord-327287-e5k2gcse 1 3 cord-327287-e5k2gcse cord-327287-e5k2gcse JJ cord-327287-e5k2gcse 1 4 authors author NNS cord-327287-e5k2gcse 1 5 : : : cord-327287-e5k2gcse 2 1 May May NNP cord-327287-e5k2gcse 2 2 , , , cord-327287-e5k2gcse 2 3 Jori Jori NNP cord-327287-e5k2gcse 2 4 E. E. NNP cord-327287-e5k2gcse 2 5 ; ; : cord-327287-e5k2gcse 2 6 Siniard Siniard NNP cord-327287-e5k2gcse 2 7 , , , cord-327287-e5k2gcse 2 8 Rance Rance NNP cord-327287-e5k2gcse 2 9 C. C. NNP cord-327287-e5k2gcse 2 10 ; ; : cord-327287-e5k2gcse 2 11 Marques Marques NNP cord-327287-e5k2gcse 2 12 , , , cord-327287-e5k2gcse 2 13 Marisa Marisa NNP cord-327287-e5k2gcse 2 14 title title NN cord-327287-e5k2gcse 2 15 : : : cord-327287-e5k2gcse 2 16 The the DT cord-327287-e5k2gcse 2 17 challenges challenge NNS cord-327287-e5k2gcse 2 18 of of IN cord-327287-e5k2gcse 2 19 diagnosing diagnose VBG cord-327287-e5k2gcse 2 20 heparin‐induced heparin‐induced JJ cord-327287-e5k2gcse 2 21 thrombocytopenia thrombocytopenia NN cord-327287-e5k2gcse 2 22 in in IN cord-327287-e5k2gcse 2 23 patients patient NNS cord-327287-e5k2gcse 2 24 with with IN cord-327287-e5k2gcse 2 25 COVID‐19 COVID‐19 NNP cord-327287-e5k2gcse 2 26 date date NN cord-327287-e5k2gcse 2 27 : : : cord-327287-e5k2gcse 2 28 2020 2020 CD cord-327287-e5k2gcse 2 29 - - HYPH cord-327287-e5k2gcse 2 30 08 08 CD cord-327287-e5k2gcse 2 31 - - HYPH cord-327287-e5k2gcse 2 32 02 02 CD cord-327287-e5k2gcse 2 33 journal journal NN cord-327287-e5k2gcse 2 34 : : : cord-327287-e5k2gcse 2 35 Res Res NNP cord-327287-e5k2gcse 2 36 Pract Pract NNP cord-327287-e5k2gcse 2 37 Thromb Thromb NNP cord-327287-e5k2gcse 2 38 Haemost Haemost NNP cord-327287-e5k2gcse 2 39 DOI DOI NNP cord-327287-e5k2gcse 2 40 : : : cord-327287-e5k2gcse 3 1 10.1002 10.1002 CD cord-327287-e5k2gcse 3 2 / / SYM cord-327287-e5k2gcse 3 3 rth2.12416 rth2.12416 NN cord-327287-e5k2gcse 3 4 sha sha NNP cord-327287-e5k2gcse 3 5 : : : cord-327287-e5k2gcse 4 1 6cf379514f4a50a6c052d7f69520b096515e6257 6cf379514f4a50a6c052d7f69520b096515e6257 CD cord-327287-e5k2gcse 4 2 doc_id doc_id CD cord-327287-e5k2gcse 4 3 : : : cord-327287-e5k2gcse 5 1 327287 327287 CD cord-327287-e5k2gcse 5 2 cord_uid cord_uid NN cord-327287-e5k2gcse 5 3 : : : cord-327287-e5k2gcse 5 4 e5k2gcse e5k2gcse NNP cord-327287-e5k2gcse 5 5 nan nan NNP cord-327287-e5k2gcse 6 1 To to IN cord-327287-e5k2gcse 6 2 the the DT cord-327287-e5k2gcse 6 3 Editor Editor NNP cord-327287-e5k2gcse 6 4 , , , cord-327287-e5k2gcse 6 5 Riker Riker NNP cord-327287-e5k2gcse 6 6 EIAs EIAs NNP cord-327287-e5k2gcse 6 7 are be VBP cord-327287-e5k2gcse 6 8 sensitive sensitive JJ cord-327287-e5k2gcse 6 9 , , , cord-327287-e5k2gcse 6 10 but but CC cord-327287-e5k2gcse 6 11 not not RB cord-327287-e5k2gcse 6 12 specific specific JJ cord-327287-e5k2gcse 6 13 , , , cord-327287-e5k2gcse 6 14 for for IN cord-327287-e5k2gcse 6 15 HIT HIT VBN cord-327287-e5k2gcse 6 16 diagnosis diagnosis NN cord-327287-e5k2gcse 6 17 because because IN cord-327287-e5k2gcse 6 18 they -PRON- PRP cord-327287-e5k2gcse 6 19 detect detect VBP cord-327287-e5k2gcse 6 20 all all DT cord-327287-e5k2gcse 6 21 anti anti JJ cord-327287-e5k2gcse 6 22 - - JJ cord-327287-e5k2gcse 6 23 platelet platelet JJ cord-327287-e5k2gcse 6 24 factor factor NN cord-327287-e5k2gcse 6 25 4 4 CD cord-327287-e5k2gcse 6 26 ( ( -LRB- cord-327287-e5k2gcse 6 27 PF4)/heparin PF4)/heparin NNP cord-327287-e5k2gcse 6 28 antibodies antibody NNS cord-327287-e5k2gcse 6 29 , , , cord-327287-e5k2gcse 6 30 including include VBG cord-327287-e5k2gcse 6 31 those those DT cord-327287-e5k2gcse 6 32 that that WDT cord-327287-e5k2gcse 6 33 are be VBP cord-327287-e5k2gcse 6 34 nonpathogenic nonpathogenic JJ cord-327287-e5k2gcse 6 35 . . . cord-327287-e5k2gcse 7 1 3 3 LS cord-327287-e5k2gcse 8 1 In in IN cord-327287-e5k2gcse 8 2 contrast contrast NN cord-327287-e5k2gcse 8 3 , , , cord-327287-e5k2gcse 8 4 functional functional JJ cord-327287-e5k2gcse 8 5 assays assay NNS cord-327287-e5k2gcse 8 6 ( ( -LRB- cord-327287-e5k2gcse 8 7 including include VBG cord-327287-e5k2gcse 8 8 SRA SRA NNP cord-327287-e5k2gcse 8 9 ) ) -RRB- cord-327287-e5k2gcse 8 10 identify identify VBP cord-327287-e5k2gcse 8 11 only only RB cord-327287-e5k2gcse 8 12 antibodies antibody NNS cord-327287-e5k2gcse 8 13 with with IN cord-327287-e5k2gcse 8 14 the the DT cord-327287-e5k2gcse 8 15 pathogenic pathogenic JJ cord-327287-e5k2gcse 8 16 ability ability NN cord-327287-e5k2gcse 8 17 to to TO cord-327287-e5k2gcse 8 18 activate activate VB cord-327287-e5k2gcse 8 19 platelets platelet NNS cord-327287-e5k2gcse 8 20 and and CC cord-327287-e5k2gcse 8 21 therefore therefore RB cord-327287-e5k2gcse 8 22 have have VBP cord-327287-e5k2gcse 8 23 increased increase VBN cord-327287-e5k2gcse 8 24 specificity specificity NN cord-327287-e5k2gcse 8 25 . . . cord-327287-e5k2gcse 9 1 3 3 LS cord-327287-e5k2gcse 10 1 Given give VBN cord-327287-e5k2gcse 10 2 that that DT cord-327287-e5k2gcse 10 3 severe severe JJ cord-327287-e5k2gcse 10 4 COVID-19 covid-19 NN cord-327287-e5k2gcse 10 5 is be VBZ cord-327287-e5k2gcse 10 6 a a DT cord-327287-e5k2gcse 10 7 hyperinflammatory hyperinflammatory JJ cord-327287-e5k2gcse 10 8 state state NN cord-327287-e5k2gcse 10 9 , , , cord-327287-e5k2gcse 10 10 it -PRON- PRP cord-327287-e5k2gcse 10 11 is be VBZ cord-327287-e5k2gcse 10 12 plausible plausible JJ cord-327287-e5k2gcse 10 13 that that IN cord-327287-e5k2gcse 10 14 the the DT cord-327287-e5k2gcse 10 15 increased increase VBN cord-327287-e5k2gcse 10 16 immunoreactivity immunoreactivity NN cord-327287-e5k2gcse 10 17 also also RB cord-327287-e5k2gcse 10 18 increases increase VBZ cord-327287-e5k2gcse 10 19 production production NN cord-327287-e5k2gcse 10 20 of of IN cord-327287-e5k2gcse 10 21 anti anti JJ cord-327287-e5k2gcse 10 22 - - JJ cord-327287-e5k2gcse 10 23 PF4 pf4 JJ cord-327287-e5k2gcse 10 24 / / SYM cord-327287-e5k2gcse 10 25 heparin heparin NN cord-327287-e5k2gcse 10 26 antibodies antibody NNS cord-327287-e5k2gcse 10 27 ; ; : cord-327287-e5k2gcse 10 28 however however RB cord-327287-e5k2gcse 10 29 , , , cord-327287-e5k2gcse 10 30 they -PRON- PRP cord-327287-e5k2gcse 10 31 may may MD cord-327287-e5k2gcse 10 32 not not RB cord-327287-e5k2gcse 10 33 result result VB cord-327287-e5k2gcse 10 34 in in IN cord-327287-e5k2gcse 10 35 clinical clinical JJ cord-327287-e5k2gcse 10 36 HIT hit NN cord-327287-e5k2gcse 10 37 but but CC cord-327287-e5k2gcse 10 38 may may MD cord-327287-e5k2gcse 10 39 instead instead RB cord-327287-e5k2gcse 10 40 increase increase VB cord-327287-e5k2gcse 10 41 potential potential NN cord-327287-e5k2gcse 10 42 for for IN cord-327287-e5k2gcse 10 43 false false JJ cord-327287-e5k2gcse 10 44 - - HYPH cord-327287-e5k2gcse 10 45 positive positive JJ cord-327287-e5k2gcse 10 46 EIAs eias NN cord-327287-e5k2gcse 10 47 . . . cord-327287-e5k2gcse 11 1 Herein herein RB cord-327287-e5k2gcse 11 2 , , , cord-327287-e5k2gcse 11 3 we -PRON- PRP cord-327287-e5k2gcse 11 4 report report VBP cord-327287-e5k2gcse 11 5 our -PRON- PRP$ cord-327287-e5k2gcse 11 6 experience experience NN cord-327287-e5k2gcse 11 7 with with IN cord-327287-e5k2gcse 11 8 hospitalized hospitalize VBN cord-327287-e5k2gcse 11 9 patients patient NNS cord-327287-e5k2gcse 11 10 with with IN cord-327287-e5k2gcse 11 11 _SP cord-327287-e5k2gcse 12 1 The the DT cord-327287-e5k2gcse 12 2 authors author NNS cord-327287-e5k2gcse 12 3 have have VBP cord-327287-e5k2gcse 12 4 no no DT cord-327287-e5k2gcse 12 5 conflicts conflict NNS cord-327287-e5k2gcse 12 6 of of IN cord-327287-e5k2gcse 12 7 interest interest NN cord-327287-e5k2gcse 12 8 to to TO cord-327287-e5k2gcse 12 9 disclose disclose VB cord-327287-e5k2gcse 12 10 . . . cord-327287-e5k2gcse 12 11 _SP cord-327287-e5k2gcse 13 1 Heparin heparin NN cord-327287-e5k2gcse 13 2 - - HYPH cord-327287-e5k2gcse 13 3 induced induce VBN cord-327287-e5k2gcse 13 4 thrombocytopenia thrombocytopenia NN cord-327287-e5k2gcse 13 5 with with IN cord-327287-e5k2gcse 13 6 thrombosis thrombosis NN cord-327287-e5k2gcse 13 7 in in IN cord-327287-e5k2gcse 13 8 COVID-19 covid-19 JJ cord-327287-e5k2gcse 13 9 adult adult JJ cord-327287-e5k2gcse 13 10 respiratory respiratory JJ cord-327287-e5k2gcse 13 11 distress distress NN cord-327287-e5k2gcse 13 12 syndrome syndrome NN cord-327287-e5k2gcse 14 1 COVID-19 covid-19 VB cord-327287-e5k2gcse 14 2 and and CC cord-327287-e5k2gcse 14 3 its -PRON- PRP$ cord-327287-e5k2gcse 14 4 implications implication NNS cord-327287-e5k2gcse 14 5 for for IN cord-327287-e5k2gcse 14 6 thrombosis thrombosis NN cord-327287-e5k2gcse 14 7 and and CC cord-327287-e5k2gcse 14 8 anticoagulation anticoagulation NN cord-327287-e5k2gcse 14 9 Testing testing NN cord-327287-e5k2gcse 14 10 for for IN cord-327287-e5k2gcse 14 11 heparin heparin NN cord-327287-e5k2gcse 14 12 - - HYPH cord-327287-e5k2gcse 14 13 induced induce VBN cord-327287-e5k2gcse 14 14 thrombocytopenia thrombocytopenia NN cord-327287-e5k2gcse 14 15 antibodies antibody NNS