id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-354700-bdpp3qmf	Lanzavecchia, Antonio	Dissecting human antibody responses: useful, basic and surprising findings	2018-01-23		.txt	text/plain	3112	114	36	I will discuss how a target‐agnostic approach based on high‐throughput screening of antibodies produced by cultured B cells and plasma cells has not only provided potent and broadly neutralizing antibodies against a range of pathogens, but has also advanced our understanding of basic aspects of the immune response, from host–pathogen interaction to the role of somatic mutations in affinity maturation and in the diversification of the antibody response. I will discuss how a target-agnostic approach based on highthroughput screening of antibodies produced by cultured B cells and plasma cells has not only provided potent and broadly neutralizing antibodies against a range of pathogens, but has also advanced our understanding of basic aspects of the immune response, from host-pathogen interaction to the role of somatic mutations in affinity maturation and in the diversification of the antibody response.	./cache/cord-354700-bdpp3qmf.txt	./txt/cord-354700-bdpp3qmf.txt