id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-339520-odly2fwg	Madic, J.	Isotype-specific antibody responses to bovine herpesvirus 1 in sera and mucosal secretions of calves after experimental reinfection and after reactivation	1995-07-31		.txt	text/plain	3360	172	49	Abstract Isotype-specific antibody responses to bovine herpesvirus 1 (BHV1) were measured in sera, nasal, ocular and genital secretions of calves that were reinfected with BHV1 and 6 weeks later treated with corticosteroids to reactivate putative latent virus. The control calves, which were infected for the first time, developed an IgM antibody response in serum, nasal and ocular secretions that was first detected on PRD 8 and lasted until PRD 27. Calves in which no virus excretion after reinfection and/or corticosteroid treatment was detected yet developed an antibody response against BHVl, mainly of the IgA isotype. However, it may be the serum IgA response seems to be a much more sensitive indicator for reinfection with or reactivation of BHVl than detection of nasal and ocular virus shedding. After corticosteroid treatment, virus-positive nasal secretions were detected in 20 of 26 reinfected calves, and a significant increase in serum IgGl and IgG2 antibody titre in 17 and 12 calves, respectively.	./cache/cord-339520-odly2fwg.txt	./txt/cord-339520-odly2fwg.txt