id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-283641-2u16otbf	Vainionpää, R.	Diagnostic Techniques: Serological and Molecular Approaches	2015-03-06		.txt	text/plain	4400	222	40	For diagnostic purposes the following approaches can be used: demonstration of presence of infectious virus or its structural components directly from a patient's specimens or investigation of specific antibody response in serum specimens. Glossary EIA Enzyme immunoassays are methods used to estimate virus-specific IgG and IgM antibodies or virus antigens by enzyme-labeled conjugates. Nucleic acid testing has become the main approach for the demonstration of the presence of virus while cultivation is used by fewer specialized laboratories and antigen detection methods have moved to the point of care. Diagnostic applications of the measurement of the avidity of IgG antibodies against specific antigens have been developed to help distinguish serological responses due to acute infections from those of chronic or past infections. In immunofluorescence tests, cells from a clinical specimen are fixed on a glass slide and viral antigens present in the cells are detected by fluorescein-labeled virus-specific antibodies.	./cache/cord-283641-2u16otbf.txt	./txt/cord-283641-2u16otbf.txt