id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-279105-e2zjxjox	Lee, Cheryl Yi-Pin	Serological Approaches for COVID-19: Epidemiologic Perspective on Surveillance and Control	2020-04-24		.txt	text/plain	3872	212	44	With the limitations of qRT-PCR, immunoassays may offer another FIGURE 2 | Schematic illustration on the window period of detection for either viral RNA or antibodies in SARS-CoV-2-infected individuals. However, interestingly, one study demonstrated that longitudinal profiling of both antibodies in a population of 63 COVID-19 patients showed no specific chronological order in terms of IgM and IgG seroconversion (10) , which was also observed in patients infected with SARS-CoV and another human coronavirus, Middle East Respiratory Syndrome coronavirus (MERS-CoV) (22, 23) . These findings on SARS-CoV-2-specific antibodies seroconversion against the S viral protein suggest the importance to test for both IgM and IgG antibodies to confirm a positive infection. With the availability of immunoassays utilizing various coronavirus structural proteins, the use of more than one different antigen-based serological approach may be essential to establish a true positive SARS-CoV-2 infection.	./cache/cord-279105-e2zjxjox.txt	./txt/cord-279105-e2zjxjox.txt