id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261274-y74smbtd	Crouch, C. F	Lactogenic immunity following vaccination of cattle with bovine coronavirus	2000-09-15		.txt	text/plain	4173	177	53	Abstract In order to investigate the ability of an oil adjuvanted vaccine containing bovine coronavirus antigen to enhance lactogenic immunity in the calf, pregnant cows and heifers were vaccinated and specific virus neutralising antibody levels determined in serum, colostrum and milk. Pre-existing antibody titres (as a result of natural infection) in the serum of these animals were found to be significantly increased as a result of a single shot vaccination carried out between 2 and 12 weeks before calving. This hypothesis was supported by the observations on the magnitude of the antibody titres found in the colostrum and milk of cows vaccinated at dierent times pre-calving with a vaccine containing 150 antigen units of BCoV. This report indicates that a single dose of coronavirus vaccine administered to the pregnant heifer 2 to 12 weeks before calving is capable of signi®cantly increasing the titre and duration of speci®c antibody present in colostrum and milk.	./cache/cord-261274-y74smbtd.txt	./txt/cord-261274-y74smbtd.txt