id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-010991-fp8hljbq	Rather, Shabeer Ahmad	Antibodies generated against dextransucrase exhibit potential anticariostatic properties in Streptococcus mutans	2020-01-03		.txt	text/plain	6593	363	48	For vaccine development, attention was paid on the purified antigens involved in the pathogenesis of dental caries for the development of potentially safer vaccines, which may reduce the viability of bacteria in the saliva, impairing the surface adhesion and inhibiting the metabolically active enzymes involved in caries formation (Chen and Wang 2010) . mutans have shown encouraging results related to dental caries protection, but were limited by the cross-reactive epitopes against human heart and skeleton muscle tissues as detected by indirect immunofluorescence and crossed immunoelectrophoresis (Kt et al. In the present study, we have tried to evaluate the effect of anti-dextransucrase antibodies on caries formation by using purified dextransucrase as the antigen from S. Protein samples of the liver, heart, spleen, kidney of mice, rat and liver, kidney of rabbit were analysed by western blot analysis to evaluate the cross reactivity of purified antibody with mammalian tissues Fig. 5a .	./cache/cord-010991-fp8hljbq.txt	./txt/cord-010991-fp8hljbq.txt