id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-286574-t9z2ynt5	nan	Speaker presentations	2017-09-30		.txt	text/plain	14833	690	40	Data on the economic impact of AMR in major pathogens showed that healthcare costs significantly increase in the treatment of infections caused by antibiotic-resistant strains (Maragakis et al. In principle, the major high-level goals consist of optimizing the use of such drugs in health and agriculture and minimizing environmental contamination; sustaining the development of new classes of antimicrobials drugs and other medicines and making them affordable and accessible to all who need them; and much more effective application of infection control and prevention principles. These new agents are bound to change the paradigm for the treatment of infections caused by colistin-resistant Gram-negatives, but uncertainties are still likely to remain, including which agent to use, how to optimize dosing in to maximize efficacy and minimize toxicity as well as potential for development of resistance, and whether use of more than one agent would still be needed.	./cache/cord-286574-t9z2ynt5.txt	./txt/cord-286574-t9z2ynt5.txt