id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-010012-1hrx1w8r	Destache, Christopher J.	Optimizing Economic Outcomes in Acute Exacerbations of Chronic Bronchitis	2012-01-17		.txt	text/plain	2655	148	35	The treatment of community‐acquired respiratory tract infections, such as acute exacerbations of chronic bronchitis (AECB), constitutes a huge socioeconomic burden. The treatment of community-acquired respiratory tract infections (RTIs), such as acute exacerbations of chronic bronchitis (AECB), constitutes a huge socioeconomic burden. Indeed, antibiotic treatment is associated with lower relapse rates, longer periods between exacerbations, shorter duration of symptoms, and reduced hospitalizations. However, studies of antibiotic therapy for AECB have failed to either account for differences among patients or examine the effect of increasing rates of antimicrobial resistance on clinical and economic outcomes. 22 It was concluded that this study found that in patients with COPD experiencing an AECB, the use of third-line antibiotics significantly reduced treatment failure rates and the need for hospitalization, while prolonging the time between AECB episodes. The infection-free interval: its use in evaluating antimicrobial treatment of acute exacerbation of chronic bronchitis	./cache/cord-010012-1hrx1w8r.txt	./txt/cord-010012-1hrx1w8r.txt