id author title date pages extension mime words sentences flesch summary cache txt cord-336884-dyju6w15 Fielding, C.L. Disease Associated with Equine Coronavirus Infection and High Case Fatality Rate 2014-10-15 .txt text/plain 2689 170 57 Outbreaks are associated with a low case fatality rate and a small number of animals with signs of encephalopathic disease are described. OBJECTIVES: The aim of this study is to describe the epidemiological and clinical features of two outbreaks of ECoV infection that were associated with an high case fatality rate. CONCLUSIONS AND CLINICAL IMPORTANCE: Equine coronavirus had a higher case fatality rate in this group of miniature horses than previously reported in other outbreaks of varying breeds. Hyperammonemia could contribute to signs of encephalopathic disease, and the fecal viral load might be of prognostic value in affected horses. Other common enteric pathogens of horses, including Salmonella enterica, Clostridium difficile, Clostridium perfringens, Lawsonia intracellularis, and Neorickettsia risticii were also investigated in feces of four of the sick horses by specific PCR. In the ID outbreak, resident farm horses displayed clinical signs of disease including decreased appetite, lethargy, and fevers ≤38.9°C approximately 2-3 days after show horses returned from competition (American Miniature Horse Association World Championship Show). ./cache/cord-336884-dyju6w15.txt ./txt/cord-336884-dyju6w15.txt