id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-006250-cdt2wcr5	van der Logt, J. T. M.	Microbiological effects and quality control in laboratory rodents	2013-07-01		.txt	text/plain	3261	193	38	The significance of biomedical research using laboratory animals has increased substantially because of the increased awareness of an-imal producers and investigators of the need to use high-quality animals with standardized microbiological status, under environmentally defined conditions, in their experiments. Programs to assess the health status of rodents, and characterize their microbiological status were improved, and monitoring data thereafter showed that breeders were able to produce and supply clean, specified pathogen free (SPF) animals (15, 16) . It is abundantly clear that for good comparison of experimental results obtained by different research groups, international standardization of programs used for microbiological characterization of SPF laboratory rodents is indispensable. Programs used for characterization of the microbiological status and routine monitoring should include daily clinical observation of the animals, histopathological searches for lesions of infectious diseases, cultures for bacteria and fungi, serological tests especially for viruses, and parasitological tests.	./cache/cord-006250-cdt2wcr5.txt	./txt/cord-006250-cdt2wcr5.txt