id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-317888-ei598viq	Sarzani, Riccardo	Antagonizing the renin–angiotensin–aldosterone system in the era of COVID-19	2020-05-18		.txt	text/plain	1326	64	49	Moreover, ACE2 interacts with another branch of RAAS based on Ang peptides in which the aminoterminal aspartate is replaced by alanine (Alatensins), leading to the production of Ala-Ang 1-7 (Alamandine) that has been found to bind Mas-related G protein-coupled receptor D (MrgD) and may also protect against lung injury and fibrosis, improving vascular/endothelial dysfunction [4] . Same favorable results have been found in a small UK cohort study on 205 patients admitted for COVID-19, in which treatment with ACE-I was associated with a reduced risk of rapidly deteriorating severe disease [pre-print] . In another small sample of COVID-19 patients, ACE-I and ARB therapy affected both IL-6 and peripheral T cell levels and was associated with lower rates of severe disease [6] . Association of renin-angiotensin system inhibitors with severity or risk of death in patients with hypertension hospitalized for coronavirus disease 2019 (COVID-19) infection in Wuhan	./cache/cord-317888-ei598viq.txt	./txt/cord-317888-ei598viq.txt