id author title date pages extension mime words sentences flesch summary cache txt cord-273595-fkk4ry62 Jing, Yan Potential influence of COVID-19/ACE2 on the female reproductive system 2020-05-04 .txt text/plain 4104 239 48 2019-nCoV infects the target cell by binding to angiotensin-converting enzyme (ACE) 2 through its surface spike protein Zhou et al., 2020) , modulates the expression of ACE2 and causes severe injuries, similar to SARS-CoV (Kuba et al., 2005; Wang and Cheng, 2020) . ACE2 presents in stroma and granulosa cells as well as oocytes in immature rat ovaries, the expression of which is enhanced in antral and preovulatory follicles subjected to equine CG treatment (Pereira et al., 2009) . (2019) reported that activation of the ACE2/Ang-(1-7)/Mas axis in hypertensive pregnant rats could attenuate the cardiovascular dysfunction in adult offspring (Bessa et al., 2019) , confirming the engagement of the ACE2 axis in pregnancy. Gonadotropin stimulation increases the expression of angiotensin-(1--7) and MAS receptor in the rat ovary Angiotensin-(1-7), its receptor Mas, and the angiotensin-converting enzyme type 2 are expressed in the human ovary Increasing Host Cellular Receptor-Angiotensin-Converting Enzyme 2 (ACE2) Expression by Coronavirus may Facilitate 2019-nCoV Infection ./cache/cord-273595-fkk4ry62.txt ./txt/cord-273595-fkk4ry62.txt