id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-016335-z2movens	Ferrario, Carlos M.	Regulation of Cardiovascular Control Mechanisms by Angiotensin-(1–7) and Angiotensin-Converting Enzyme 2	2010-06-15		.txt	text/plain	5762	266	42	There are few studies about the direct actions of Ang-(1-7) on heart function, although the peptide is highly expressed in rat myocardium (30) and can be detected in larger concentrations in the cardiac interstitium or the coronary sinus blood after acute coronary artery ligation (67) (68) (69) . That the heart may be an important site for Ang-(1-7) actions is highlighted by the demonstration that ACE activity in plasma and atrial tissue is inhibited by Ang-(1-7) (73) whereas the peptide enhances tritiated norepinephrine release from isolated atrial tissue at doses comparable to those for Ang II (74) . Indeed, immunocytochemical staining for the Ang-(1-7) receptor mas is evident in the afferent arteriole, as well as throughout the proximal tubules of the renal cortex providing biochemical support for the functional actions of the peptide (87) . The potential contribution of Ang-(1-7) to vascular control in pregnancy was also documented from increased vasodilator responses to the local application of the peptide in isolated small mesenteric arteries obtained from pregnant rats (102) .	./cache/cord-016335-z2movens.txt	./txt/cord-016335-z2movens.txt