id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-282336-zvc04s39	Choudhary, Ishita	Tristetraprolin Overexpression in Non-hematopoietic Cells Protects Against Acute Lung Injury in Mice	2020-09-02		.txt	text/plain	7910	405	48	In contrast, the lung injury in LPS-challenged TTP KO mice was characterized by severe consolidation (>90% of total area of lung section) (Figures 1F,G) that included infiltration of neutrophils, edema, fibrin, and airspace hemorrhage within the airway and alveolar lumen, multifocal loss of bronchiolar epithelium with infiltration of neutrophils and red blood cells within the bronchiolar lumen, and moderate to severe perivascular edema and inflammation (Figures 1F-H) . To determine the cell-specific role of TTP levels in ALI, we modulated TTP levels in hematopoietic progenitor cells (HPCs) and non-HPCs. In order to test whether donor HPCs repopulate the recipient mouse lungs, we first made bone marrow chimeras in which total body irradiated WT mice were transplanted with HPCs from a mouse expressing green fluorescent protein (GFP) in their somatic cells.	./cache/cord-282336-zvc04s39.txt	./txt/cord-282336-zvc04s39.txt