id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-002329-7s0ytfed	Zeng, Ling	The cellular kinetics of lung alveolar epithelial cells and its relationship with lung tissue repair after acute lung injury	2016-12-07		.txt	text/plain	5369	286	54	CONCLUSIONS: AEC2s are damage resistant during acute lung injury and the HGF/c-Met signaling pathway is of vital importance in the proliferation of AEC2s after ALI. Using a microfluidic magnetic activated cell sorting system, our previous study has isolated mouse lung multipotent stem cells (MLSCs) which play an important role in bronchiolar and alveolar epithelial cells injury repair [8] . The rat whole lung cell suspensions were incubated with FITC conjugated to anti-proSPC antibody, the percentage of AEC2s was analyzed by flow cytometry analysis (Fig. 1e) , in sham-operated mice, there were no differences in numbers of AEC2s at various time points. It can significantly accelerate AEC2 cell cycle in vitro, indicating that the proliferation of AEC2 after acute lung injury may be induced by the elevated HGF. HGF/c-Met signaling is likely a major factor responsible for the pulmonary epithelial cell proliferation after acute lung injury.	./cache/cord-002329-7s0ytfed.txt	./txt/cord-002329-7s0ytfed.txt