id author title date pages extension mime words sentences flesch summary cache txt cord-017885-cz19y60u Maziarz, Eileen K. Cryptococcosis 2014-11-24 .txt text/plain 10640 493 33 While the widespread use of highly active antiretroviral therapy (HAART) has improved the outcome of cryptococcosis in many HIV-infected patients, cryptococcosis remains an entity of considerable morbidity and mortality in many parts of the world, and restoration of host immunity can present management challenges that require individualized management. In a high-risk patient with clinical symptoms suggestive of meningitis, identification of cryptococcal antigen in CSF or serum is rapid, specific, noninvasive, and virtually diagnostic of meningoencephalitis or disseminated cryptococcosis even when the India ink examination or culture is negative [42, 43] . Though combination induction therapy with AmBd and 5-FC remains the recommended standard of care for severe cryptococcosis including cryptococcal meningitis, limited availability of 5-FC in resource-limited settings presents significant challenges for managing patients in areas where the disease burden and mortality rates are highest. ./cache/cord-017885-cz19y60u.txt ./txt/cord-017885-cz19y60u.txt