id author title date pages extension mime words sentences flesch summary cache txt cord-009338-zc88lsls Fulginiti, Vincent A. What's in store for 1984? 2007-01-26 .txt text/plain 2080 113 54 Several observers have noted unusual morphologic changes such-as vesicular rosettes in lymph node lymphoid cells and a tubular reticular structure within cisterns of smooth endoplasmic reticulae of lymphocytes from patients with AIDS.3, 4 One hypothesis to explain their occurrence is viral infection of the lymphocytes. Studies in hemophiliacs who received factor VIII therapy butnot other forms of replacement suggest that a transmissible agent, possibly in the factor VIII concentrate, results in immunologic aberrations that are not unlike those seen in AIDS. 5 Investigators have suggested a possible link between AIDS and human T-cell leukemia virus (HTLV). For years practitioners have been plagued with the increasing recognition of the viral cause of a variety of diseases and improved methods of diagnosis including rapid identification of many viruses that is not possible with the inability to significantly influence the course; morbidity or mortality associated with these infections. ./cache/cord-009338-zc88lsls.txt ./txt/cord-009338-zc88lsls.txt