id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-349786-12lc3342	Acquah, Samuel	Implications of COVID-19 Pandemic on Evolution of Diabetes in Malaria-Endemic African Region	2020-10-08		.txt	text/plain	3435	184	44	Angiotensin-converting enzyme 2 (ACE2) which is widely distributed in the human body is implicated in the pathogenesis of malaria, type 2 diabetes mellitus (T2DM), and COVID-19. With the continent already responsible for over 93% of global malaria burden and associated deaths in 2018 [6] , the presence of the COVID-19 pandemic does not only increase the infectious disease burden of the African region but could serve as another risk factor to the development of type 2 diabetes mellitus (T2DM) in the region. Just like other known coronaviruses [14, 15] , the acute respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for the COVID-19 pandemic, requires a specific receptor, angiotensin-converting enzyme 2 (ACE2), for entry into host cells [16] [17] [18] [19] . To this end, the COVID-19 virus, which reduces ACE2 levels or activities, can potentiate infected individuals for future development of T2DM through low-grade inflammation and insulin resistance.	./cache/cord-349786-12lc3342.txt	./txt/cord-349786-12lc3342.txt