id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-312183-zkoj5d8c	Frydman, Galit H.	Coagulation Status and Venous Thromboembolism Risk in African Americans: A Potential Risk Factor in COVID-19	2020-07-24		.txt	text/plain	4474	240	37	Recent studies have shown severe pulmonary and cardiac pathology, associated with increased thrombosis, is prevalent in African Americans with severe COVID-19. 65 Although clinical SCD is only present in an estimated 100 000 patients in the United States, the sickle cell trait is present in up to 8% of the African American population, with SCD flagged as an important risk factor for VTE. 87, 88 Among the population of African Americans who are infected with COVID-19, some of these patients may already reside in a prothrombotic state prior to COVID-19 because of higher baseline concentrations of FVIII, vWF, and D-dimer, as well as increased platelet activation. Coupled with the higher rate of preexisting conditions that predispose patients to higher rates of COVID-19 and disease, and the lower rate of therapeutic anticoagulation even when warranted, variation in coagulation status may be one of the factors that puts African Americans at higher risk.	./cache/cord-312183-zkoj5d8c.txt	./txt/cord-312183-zkoj5d8c.txt