id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-151532-mpv2wegm	Peng, Kerui	Diversity in immunogenomics: the value and the challenge	2020-10-20		.txt	text/plain	2792	138	28	With the recent advent of high-throughput sequencing technologies, and the associated new discoveries and developments, the fields of immunogenomics and adaptive immune receptor repertoire research are facing both opportunities and challenges. By leveraging biological and clinical heterogeneity across different populations in omics data and expanding the populations that are included in immunogenomics research, we can enhance our understanding of human adaptive immune responses, promote the development of effective diagnostics and treatments, and eventually advance precision medicine. However, challenges need to be overcome, including the high levels of copy number variation and segmental duplication in the BCR and TCR loci, and the need for protocols to validate novel allelic variants gleaned from short-read sequencing data 45, 77 Finally, we suggest the need for additional infrastructure and expertise in regions and countries with populations underrepresented in research, and to enhance collaborations between countries, which are critical in minimizing global health disparities.	./cache/cord-151532-mpv2wegm.txt	./txt/cord-151532-mpv2wegm.txt