id author title date pages extension mime words sentences flesch summary cache txt cord-017322-82nfkms8 Kumar, Anupam Respiratory Failure in a Patient with Idiopathic Pulmonary Fibrosis 2019-07-24 .txt text/plain 3649 197 38 The 2007 criteria proposed by Idiopathic Pulmonary Fibrosis Network (IPFnet) defined acute exacerbation of IPF as acute clinical worsening (<30 days) in a patient with known or newly diagnosed IPF with acceleration of dyspnea and/or hypoxemia and new radiologic changes, typically ground glass opacities, on a background of fibrotic disease (example Fig. 30 .1) [1, 2] . The classical description of pathologic insult due to acute exacerbation of IPF is diffuse alveolar damage [4] , which is the same as ARDS, but here is superimposed on the pathological findings of idiopathic pulmonary fibrosis: usual interstitial pneumonia. As idiopathic pulmonary fibrosis is a rare condition, and acute exacerbations occur spontaneously and abruptly, large a b prospective randomized trials evaluating treatment are lacking. High flow nasal cannula has been shown to have salutatory affects in idiopathic pulmonary fibrosis patients without an acute exacerbation, specifically decreased minute ventilation, respiratory rate, capillary carbon dioxide were seen [25] . ./cache/cord-017322-82nfkms8.txt ./txt/cord-017322-82nfkms8.txt