id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-330660-tx20im6w	Mahmoud, Huda K.	Nano-sized Formazan analogues: Synthesis, structure elucidation, antimicrobial activity and Docking study for COVID-19	2020-10-07		.txt	text/plain	2530	168	49	Molecular docking simulations of the synthesized compounds into leucyl-tRNA synthetase editing domain of Candida albicans suggested that most formazan analogues can fit deeply forming stable complexes in the active site. Inspired by the promising previously reported antimicrobial and antiviral activities of formazans and the urgent need of new effective antimicrobial agent and antiviral drugs to act mainly against COVID-19 and in continuation of our research work in synthesis of bioactive compounds [27] [28] [29] [30] [31] [32] , we synthesized herein a new series of nano-sized formazan analogues to study their potential as antibacterial and antifungal agents in vitro. In this study, molecular docking study of the newly synthesized formazan analogues 3a-f, 5a-h and 7a,b have been performed onto the active site of Candida albicans editing domain of cytosolic leucyl-tRNA synthetase to demonstrate their binding affinity and orientation.	./cache/cord-330660-tx20im6w.txt	./txt/cord-330660-tx20im6w.txt