id author title date pages extension mime words sentences flesch summary cache txt cord-278513-ajfpghze Boyle, John T. Demonstration of a difference in expression of maximal lactase and sucrase activity along the villus in the adult rat jejunum 1980-09-30 .txt text/plain 3218 186 51 Sectioning of the villus-crypt unit in a cryostat enabled direct comparison of the distribution of lactase and sucrase enzyme activities in the adult rat. Sectioning of the villus-crypt unit in a cryostat enabled direct comparison of the distribution of lactase and sucrase enzyme activities in the adult rat. Differences in localization of enzyme activity in turn might help explain the decrease in the ratio of lactase to sucrase (0), and acid &alactosidase (A) along the villus-crypt unit. This is the first report that directly compares distribution of lactase and sucrase activities along the crypt-villus unit of the adult rat. The more apical localization of lactase activity compared to sucrase activity on the crypt-villus unit may help to explain the vulnerability of this enzyme to acute mucosal injury (e.g., acute gastroenteritis). Although it is not stated that the activities of all enzymes were assayed on the same villus-crypt unit, the authors report a more apical distribution of jejunal lactase activity when compared to sucrase and maltase. ./cache/cord-278513-ajfpghze.txt ./txt/cord-278513-ajfpghze.txt