id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324326-q014b5ym	MURAKAMI, Makoto	Lipoquality control by phospholipase A(2) enzymes	2017-11-10		.txt	text/plain	8260	556	45	The phospholipase A(2) (PLA(2)) family comprises a group of lipolytic enzymes that typically hydrolyze the sn-2 position of glycerophospholipids to give rise to fatty acids and lysophospholipids. In terms of signal transduction, the phospholipase A 2 (PLA 2 ) reaction, which hydrolyzes the sn-2 position of phospholipids to yield fatty acids and lysophospholipids, has been considered to be of particular importance, since arachidonic acid (AA, C20:4), one of the polyunsaturated fatty acids (PUFAs) released from membrane phospholipids by PLA 2 , is metabolized by cyclooxygenases (COXs) and lipoxygenases (LOXs) to lipid mediators including prostaglandins (PGs) and leukotrienes (LTs), which are often referred to as eicosanoids (Fig. 1) . 36) cPLA 2 C (group IVE PLA 2 ) exhibits a unique transacylase activity that transfers sn-1 fatty acid of PC to an amino residue of phosphatidylethanolamine (PE) to form N-acyl-PE, a precursor of the endocannabinoid lipid mediator N-acylethanolamine.	./cache/cord-324326-q014b5ym.txt	./txt/cord-324326-q014b5ym.txt