id author title date pages extension mime words sentences flesch summary cache txt cord-267516-r99y91oo Clark, David A. Feeding associated neonatal necrotizing enterocolitis (Primary NEC) is an inflammatory bowel disease 2014-01-06 .txt text/plain 3672 214 43 title: Feeding associated neonatal necrotizing enterocolitis (Primary NEC) is an inflammatory bowel disease Neonatal necrotizing enterocolitis which develops after feeding preterm infants is characterized by severe intestinal inflammation and profound systemic metabolic acidosis. The feeding association is important as carbohydrate metabolized by the bacteria is the source of organic acids in the intestinal lumen, and the gases of pneumatosis intestinalis and portal venous tree. Several studies have shown there is a change in the intestinal flora in children who develop necrotizing enterocolitis in that the proteobacteria constitute as much as 70% of the organisms in the stool, in cases within three days preceding the clinical diagnosis of NEC [28] . The common intestinal flora found in all babies and in all intensive care nurseries may be the culprits in a subtle way, not by their invasive characteristics nor their ability to produce toxins, but simply by their ability to ferment carbohydrate and produce organic acids more quickly than the capacity of the preterm infants' defense mechanisms, the mucosa, and the portal system and liver can accommodate. ./cache/cord-267516-r99y91oo.txt ./txt/cord-267516-r99y91oo.txt