id author title date pages extension mime words sentences flesch summary cache txt cord-017813-qhsymg0r Sanchez, Sergio Bioactive Products from Fungi 2017-01-11 .txt text/plain 11633 762 47 They are excellent producers of hydrolytic enzymes, biofuels, organic acids, polysaccharides, and secondary metabolites such as antibiotics, anticancer drugs, hypocholesterolemic agents, immunosuppressants, and others. Antibiotics can be produced by fermentation, an old technique that was utilized for beer and wine production almost 8000 years ago, during the ancient Egypt and Mesopotamia era. Natural products (NPs) with high commercial value can be produced by microbial primary or secondary metabolism. Other products include anti-tumor drugs, hypocholesterolemic agents, enzyme inhibitors, gastrointestinal motor stimulators, ruminant growth stimulants, insecticides, herbicides, antiparasitics versus coccidia and helminths, and other pharmacological activities. In view of the low concentration of camptothecin in tree roots and poor yield from chemical synthesis, the fungal fermentation is very promising for industrial production of camptothecin. niger was an excellent producer of citric acid and, as a result, the Pfizer company in New York began large-scale fermentation production in 1923. ./cache/cord-017813-qhsymg0r.txt ./txt/cord-017813-qhsymg0r.txt