id sid tid token lemma pos cord-334490-42gykxdx 1 1 key key NN cord-334490-42gykxdx 1 2 : : : cord-334490-42gykxdx 2 1 cord-334490 cord-334490 NNP cord-334490-42gykxdx 2 2 - - HYPH cord-334490-42gykxdx 2 3 42gykxdx 42gykxdx CD cord-334490-42gykxdx 2 4 authors author NNS cord-334490-42gykxdx 2 5 : : : cord-334490-42gykxdx 3 1 Kammerlander Kammerlander NNP cord-334490-42gykxdx 3 2 , , , cord-334490-42gykxdx 3 3 Andreas Andreas NNP cord-334490-42gykxdx 3 4 A. a. NN cord-334490-42gykxdx 3 5 ; ; : cord-334490-42gykxdx 3 6 Mascherbauer Mascherbauer NNP cord-334490-42gykxdx 3 7 , , , cord-334490-42gykxdx 3 8 Julia Julia NNP cord-334490-42gykxdx 3 9 title title NN cord-334490-42gykxdx 3 10 : : : cord-334490-42gykxdx 3 11 COVID-19 covid-19 VB cord-334490-42gykxdx 3 12 : : : cord-334490-42gykxdx 3 13 frequently frequently RB cord-334490-42gykxdx 3 14 asked ask VBN cord-334490-42gykxdx 3 15 questions question NNS cord-334490-42gykxdx 3 16 to to IN cord-334490-42gykxdx 3 17 the the DT cord-334490-42gykxdx 3 18 cardiologist cardiologist NN cord-334490-42gykxdx 3 19 date date NN cord-334490-42gykxdx 3 20 : : : cord-334490-42gykxdx 3 21 2020 2020 CD cord-334490-42gykxdx 3 22 - - HYPH cord-334490-42gykxdx 3 23 07 07 CD cord-334490-42gykxdx 3 24 - - HYPH cord-334490-42gykxdx 3 25 24 24 CD cord-334490-42gykxdx 3 26 journal journal NN cord-334490-42gykxdx 3 27 : : : cord-334490-42gykxdx 3 28 Wien Wien NNP cord-334490-42gykxdx 3 29 Klin Klin NNP cord-334490-42gykxdx 3 30 Wochenschr Wochenschr NNP cord-334490-42gykxdx 3 31 DOI DOI NNP cord-334490-42gykxdx 3 32 : : : cord-334490-42gykxdx 3 33 10.1007 10.1007 CD cord-334490-42gykxdx 3 34 / / SYM cord-334490-42gykxdx 3 35 s00508 s00508 NNP cord-334490-42gykxdx 3 36 - - HYPH cord-334490-42gykxdx 3 37 020 020 CD cord-334490-42gykxdx 3 38 - - HYPH cord-334490-42gykxdx 3 39 01696 01696 CD cord-334490-42gykxdx 3 40 - - SYM cord-334490-42gykxdx 3 41 9 9 CD cord-334490-42gykxdx 3 42 sha sha NN cord-334490-42gykxdx 3 43 : : : cord-334490-42gykxdx 3 44 2c0dbb0597b5812e437181b7d9e99da7ee79f024 2c0dbb0597b5812e437181b7d9e99da7ee79f024 CD cord-334490-42gykxdx 3 45 doc_id doc_id CD cord-334490-42gykxdx 3 46 : : : cord-334490-42gykxdx 3 47 334490 334490 CD cord-334490-42gykxdx 3 48 cord_uid cord_uid NNS cord-334490-42gykxdx 3 49 : : : cord-334490-42gykxdx 4 1 42gykxdx 42gykxdx LS cord-334490-42gykxdx 4 2 nan nan NNP cord-334490-42gykxdx 5 1 In in IN cord-334490-42gykxdx 5 2 December December NNP cord-334490-42gykxdx 5 3 2019 2019 CD cord-334490-42gykxdx 5 4 , , , cord-334490-42gykxdx 5 5 a a DT cord-334490-42gykxdx 5 6 previously previously RB cord-334490-42gykxdx 5 7 unknown unknown JJ cord-334490-42gykxdx 5 8 betacoronavirus betacoronavirus NN cord-334490-42gykxdx 5 9 was be VBD cord-334490-42gykxdx 5 10 identified identify VBN cord-334490-42gykxdx 5 11 in in IN cord-334490-42gykxdx 5 12 a a DT cord-334490-42gykxdx 5 13 cluster cluster NN cord-334490-42gykxdx 5 14 of of IN cord-334490-42gykxdx 5 15 patients patient NNS cord-334490-42gykxdx 5 16 with with IN cord-334490-42gykxdx 5 17 pneumonia pneumonia NN cord-334490-42gykxdx 5 18 in in IN cord-334490-42gykxdx 5 19 Wuhan Wuhan NNP cord-334490-42gykxdx 5 20 , , , cord-334490-42gykxdx 5 21 China China NNP cord-334490-42gykxdx 5 22 [ [ -LRB- cord-334490-42gykxdx 5 23 1 1 CD cord-334490-42gykxdx 5 24 ] ] -RRB- cord-334490-42gykxdx 5 25 . . . cord-334490-42gykxdx 6 1 The the DT cord-334490-42gykxdx 6 2 pathogen pathogen NN cord-334490-42gykxdx 6 3 was be VBD cord-334490-42gykxdx 6 4 later later RB cord-334490-42gykxdx 6 5 named name VBN cord-334490-42gykxdx 6 6 severe severe JJ cord-334490-42gykxdx 6 7 acute acute JJ cord-334490-42gykxdx 6 8 respiratory respiratory JJ cord-334490-42gykxdx 6 9 syndrome syndrome NN cord-334490-42gykxdx 6 10 coronavirus coronavirus NN cord-334490-42gykxdx 6 11 2 2 CD cord-334490-42gykxdx 7 1 ( ( -LRB- cord-334490-42gykxdx 7 2 SARS SARS NNP cord-334490-42gykxdx 7 3 - - HYPH cord-334490-42gykxdx 7 4 CoV-2 CoV-2 NNP cord-334490-42gykxdx 7 5 ) ) -RRB- cord-334490-42gykxdx 7 6 , , , cord-334490-42gykxdx 7 7 sharing share VBG cord-334490-42gykxdx 7 8 similarities similarity NNS cord-334490-42gykxdx 7 9 with with IN cord-334490-42gykxdx 7 10 already already RB cord-334490-42gykxdx 7 11 known know VBN cord-334490-42gykxdx 7 12 SARS SARS NNP cord-334490-42gykxdx 7 13 strains strain NNS cord-334490-42gykxdx 7 14 . . . cord-334490-42gykxdx 8 1 The the DT cord-334490-42gykxdx 8 2 disease disease NN cord-334490-42gykxdx 8 3 caused cause VBN cord-334490-42gykxdx 8 4 by by IN cord-334490-42gykxdx 8 5 SARS SARS NNP cord-334490-42gykxdx 8 6 - - HYPH cord-334490-42gykxdx 8 7 CoV-2 CoV-2 NNP cord-334490-42gykxdx 8 8 was be VBD cord-334490-42gykxdx 8 9 named name VBN cord-334490-42gykxdx 8 10 coronavirus coronavirus NN cord-334490-42gykxdx 8 11 disease disease NN cord-334490-42gykxdx 8 12 2019 2019 CD cord-334490-42gykxdx 8 13 ( ( -LRB- cord-334490-42gykxdx 8 14 COVID-19 COVID-19 NNP cord-334490-42gykxdx 8 15 ) ) -RRB- cord-334490-42gykxdx 8 16 [ [ -LRB- cord-334490-42gykxdx 8 17 2 2 CD cord-334490-42gykxdx 8 18 ] ] -RRB- cord-334490-42gykxdx 8 19 . . . cord-334490-42gykxdx 9 1 The the DT cord-334490-42gykxdx 9 2 main main JJ cord-334490-42gykxdx 9 3 symptoms symptom NNS cord-334490-42gykxdx 9 4 of of IN cord-334490-42gykxdx 9 5 COVID-19 COVID-19 NNP cord-334490-42gykxdx 9 6 are be VBP cord-334490-42gykxdx 9 7 cough cough NN cord-334490-42gykxdx 9 8 and and CC cord-334490-42gykxdx 9 9 fever fever NN cord-334490-42gykxdx 9 10 , , , cord-334490-42gykxdx 9 11 although although IN cord-334490-42gykxdx 9 12 a a DT cord-334490-42gykxdx 9 13 broad broad JJ cord-334490-42gykxdx 9 14 spectrum spectrum NN cord-334490-42gykxdx 9 15 of of IN cord-334490-42gykxdx 9 16 symptoms symptom NNS cord-334490-42gykxdx 9 17 have have VBP cord-334490-42gykxdx 9 18 been be VBN cord-334490-42gykxdx 9 19 described describe VBN cord-334490-42gykxdx 9 20 , , , cord-334490-42gykxdx 9 21 including include VBG cord-334490-42gykxdx 9 22 the the DT cord-334490-42gykxdx 9 23 absence absence NN cord-334490-42gykxdx 9 24 of of IN cord-334490-42gykxdx 9 25 both both DT cord-334490-42gykxdx 9 26 fever fever NN cord-334490-42gykxdx 9 27 and and CC cord-334490-42gykxdx 9 28 cough cough NN cord-334490-42gykxdx 9 29 in in IN cord-334490-42gykxdx 9 30 patients patient NNS cord-334490-42gykxdx 9 31 admitted admit VBN cord-334490-42gykxdx 9 32 to to IN cord-334490-42gykxdx 9 33 the the DT cord-334490-42gykxdx 9 34 intensive intensive JJ cord-334490-42gykxdx 9 35 care care NN cord-334490-42gykxdx 9 36 unit unit NN cord-334490-42gykxdx 9 37 ( ( -LRB- cord-334490-42gykxdx 9 38 ICU ICU NNP cord-334490-42gykxdx 9 39 ) ) -RRB- cord-334490-42gykxdx 9 40 with with IN cord-334490-42gykxdx 9 41 acute acute JJ cord-334490-42gykxdx 9 42 respiratory respiratory JJ cord-334490-42gykxdx 9 43 syndrome syndrome NN cord-334490-42gykxdx 9 44 ( ( -LRB- cord-334490-42gykxdx 9 45 ARDS ARDS NNP cord-334490-42gykxdx 9 46 ) ) -RRB- cord-334490-42gykxdx 9 47 in in IN cord-334490-42gykxdx 9 48 need need NN cord-334490-42gykxdx 9 49 of of IN cord-334490-42gykxdx 9 50 mechanical mechanical JJ cord-334490-42gykxdx 9 51 ventilation ventilation NN cord-334490-42gykxdx 9 52 [ [ -LRB- cord-334490-42gykxdx 9 53 2 2 CD cord-334490-42gykxdx 9 54 ] ] -RRB- cord-334490-42gykxdx 9 55 . . . cord-334490-42gykxdx 10 1 Given give VBN cord-334490-42gykxdx 10 2 the the DT cord-334490-42gykxdx 10 3 presumably presumably RB cord-334490-42gykxdx 10 4 high high JJ cord-334490-42gykxdx 10 5 number number NN cord-334490-42gykxdx 10 6 of of IN cord-334490-42gykxdx 10 7 undetected undetected JJ cord-334490-42gykxdx 10 8 mild mild JJ cord-334490-42gykxdx 10 9 COVID-19 covid-19 JJ cord-334490-42gykxdx 10 10 cases case NNS cord-334490-42gykxdx 10 11 , , , cord-334490-42gykxdx 10 12 exact exact JJ cord-334490-42gykxdx 10 13 case case NN cord-334490-42gykxdx 10 14 fatality fatality NN cord-334490-42gykxdx 10 15 rates rate NNS cord-334490-42gykxdx 10 16 are be VBP cord-334490-42gykxdx 10 17 currently currently RB cord-334490-42gykxdx 10 18 unknown unknown JJ cord-334490-42gykxdx 10 19 [ [ -LRB- cord-334490-42gykxdx 10 20 3 3 CD cord-334490-42gykxdx 10 21 , , , cord-334490-42gykxdx 10 22 4 4 CD cord-334490-42gykxdx 10 23 ] ] -RRB- cord-334490-42gykxdx 10 24 . . . cord-334490-42gykxdx 11 1 Identification identification NN cord-334490-42gykxdx 11 2 of of IN cord-334490-42gykxdx 11 3 patients patient NNS cord-334490-42gykxdx 11 4 at at IN cord-334490-42gykxdx 11 5 highest high JJS cord-334490-42gykxdx 11 6 risk risk NN cord-334490-42gykxdx 11 7 , , , cord-334490-42gykxdx 11 8 hence hence RB cord-334490-42gykxdx 11 9 , , , cord-334490-42gykxdx 11 10 is be VBZ cord-334490-42gykxdx 11 11 crucial crucial JJ cord-334490-42gykxdx 11 12 to to TO cord-334490-42gykxdx 11 13 optimize optimize VB cord-334490-42gykxdx 11 14 patient patient JJ cord-334490-42gykxdx 11 15 triage triage NN cord-334490-42gykxdx 11 16 , , , cord-334490-42gykxdx 11 17 particularly particularly RB cord-334490-42gykxdx 11 18 with with IN cord-334490-42gykxdx 11 19 respect respect NN cord-334490-42gykxdx 11 20 to to IN cord-334490-42gykxdx 11 21 ICU ICU NNP cord-334490-42gykxdx 11 22 capacities capacity NNS cord-334490-42gykxdx 11 23 . . . cord-334490-42gykxdx 12 1 COVID-19 COVID-19 NNP cord-334490-42gykxdx 12 2 is be VBZ cord-334490-42gykxdx 12 3 considered consider VBN cord-334490-42gykxdx 12 4 primarily primarily RB cord-334490-42gykxdx 12 5 a a DT cord-334490-42gykxdx 12 6 respiratory respiratory JJ cord-334490-42gykxdx 12 7 disease disease NN cord-334490-42gykxdx 12 8 ; ; : cord-334490-42gykxdx 12 9 however however RB cord-334490-42gykxdx 12 10 , , , cord-334490-42gykxdx 12 11 patients patient NNS cord-334490-42gykxdx 12 12 with with IN cord-334490-42gykxdx 12 13 cardiovascular cardiovascular JJ cord-334490-42gykxdx 12 14 disease disease NN cord-334490-42gykxdx 12 15 represent represent VBP cord-334490-42gykxdx 12 16 a a DT cord-334490-42gykxdx 12 17 vulnerable vulnerable JJ cord-334490-42gykxdx 12 18 population population NN cord-334490-42gykxdx 12 19 during during IN cord-334490-42gykxdx 12 20 this this DT cord-334490-42gykxdx 12 21 pandemic pandemic NN cord-334490-42gykxdx 12 22 . . . cord-334490-42gykxdx 13 1 Furthermore furthermore RB cord-334490-42gykxdx 13 2 , , , cord-334490-42gykxdx 13 3 cardiac cardiac JJ cord-334490-42gykxdx 13 4 injury injury NN cord-334490-42gykxdx 13 5 in in IN cord-334490-42gykxdx 13 6 patients patient NNS cord-334490-42gykxdx 13 7 with with IN cord-334490-42gykxdx 13 8 COVID-19 COVID-19 NNP cord-334490-42gykxdx 13 9 , , , cord-334490-42gykxdx 13 10 defined define VBN cord-334490-42gykxdx 13 11 as as IN cord-334490-42gykxdx 13 12 a a DT cord-334490-42gykxdx 13 13 rise rise NN cord-334490-42gykxdx 13 14 of of IN cord-334490-42gykxdx 13 15 highly highly RB cord-334490-42gykxdx 13 16 sensitive sensitive JJ cord-334490-42gykxdx 13 17 troponin troponin JJ cord-334490-42gykxdx 13 18 levels level NNS cord-334490-42gykxdx 13 19 , , , cord-334490-42gykxdx 13 20 has have VBZ cord-334490-42gykxdx 13 21 been be VBN cord-334490-42gykxdx 13 22 identified identify VBN cord-334490-42gykxdx 13 23 as as IN cord-334490-42gykxdx 13 24 a a DT cord-334490-42gykxdx 13 25 strong strong JJ cord-334490-42gykxdx 13 26 predictor predictor NN cord-334490-42gykxdx 13 27 of of IN cord-334490-42gykxdx 13 28 morbidity morbidity NN cord-334490-42gykxdx 13 29 and and CC cord-334490-42gykxdx 13 30 mortality mortality NN cord-334490-42gykxdx 13 31 in in IN cord-334490-42gykxdx 13 32 COVID-19 covid-19 JJ cord-334490-42gykxdx 13 33 patients patient NNS cord-334490-42gykxdx 13 34 . . . cord-334490-42gykxdx 14 1 The the DT cord-334490-42gykxdx 14 2 prevalence prevalence NN cord-334490-42gykxdx 14 3 of of IN cord-334490-42gykxdx 14 4 cardiac cardiac JJ cord-334490-42gykxdx 14 5 injury injury NN cord-334490-42gykxdx 14 6 in in IN cord-334490-42gykxdx 14 7 hospitalized hospitalize VBN cord-334490-42gykxdx 14 8 patients patient NNS cord-334490-42gykxdx 14 9 was be VBD cord-334490-42gykxdx 14 10 reported report VBN cord-334490-42gykxdx 14 11 to to TO cord-334490-42gykxdx 14 12 range range VB cord-334490-42gykxdx 14 13 between between IN cord-334490-42gykxdx 14 14 20 20 CD cord-334490-42gykxdx 14 15 % % NN cord-334490-42gykxdx 14 16 and and CC cord-334490-42gykxdx 14 17 30 30 CD cord-334490-42gykxdx 14 18 % % NN cord-334490-42gykxdx 14 19 [ [ -LRB- cord-334490-42gykxdx 14 20 5 5 CD cord-334490-42gykxdx 14 21 , , , cord-334490-42gykxdx 14 22 6 6 CD cord-334490-42gykxdx 14 23 ] ] -RRB- cord-334490-42gykxdx 14 24 . . . cord-334490-42gykxdx 15 1 The the DT cord-334490-42gykxdx 15 2 specific specific JJ cord-334490-42gykxdx 15 3 causes cause NNS cord-334490-42gykxdx 15 4 of of IN cord-334490-42gykxdx 15 5 troponin troponin JJ cord-334490-42gykxdx 15 6 rise rise NN cord-334490-42gykxdx 15 7 in in IN cord-334490-42gykxdx 15 8 COVID-19 COVID-19 NNP cord-334490-42gykxdx 15 9 in in IN cord-334490-42gykxdx 15 10 patients patient NNS cord-334490-42gykxdx 15 11 without without IN cord-334490-42gykxdx 15 12 cardiac cardiac JJ cord-334490-42gykxdx 15 13 conditions condition NNS cord-334490-42gykxdx 15 14 , , , cord-334490-42gykxdx 15 15 such such JJ cord-334490-42gykxdx 15 16 as as IN cord-334490-42gykxdx 15 17 acute acute JJ cord-334490-42gykxdx 15 18 coronary coronary JJ cord-334490-42gykxdx 15 19 syndrome syndrome NN cord-334490-42gykxdx 15 20 ( ( -LRB- cord-334490-42gykxdx 15 21 ACS ACS NNP cord-334490-42gykxdx 15 22 ) ) -RRB- cord-334490-42gykxdx 15 23 , , , cord-334490-42gykxdx 15 24 aortic aortic JJ cord-334490-42gykxdx 15 25 stenosis stenosis NN cord-334490-42gykxdx 15 26 , , , cord-334490-42gykxdx 15 27 hypertrophic hypertrophic JJ cord-334490-42gykxdx 15 28 cardiomyopathy cardiomyopathy NN cord-334490-42gykxdx 15 29 , , , cord-334490-42gykxdx 15 30 and and CC cord-334490-42gykxdx 15 31 tachycardia tachycardia NN cord-334490-42gykxdx 15 32 A. a. NN cord-334490-42gykxdx 15 33 A. a. NN cord-334490-42gykxdx 15 34 Kammerlander Kammerlander NNP cord-334490-42gykxdx 15 35 , , , cord-334490-42gykxdx 15 36 MD MD NNP cord-334490-42gykxdx 15 37 , , , cord-334490-42gykxdx 16 1 PhD PhD NNP cord-334490-42gykxdx 16 2 · · NFP cord-334490-42gykxdx 16 3 ao ao NNP cord-334490-42gykxdx 16 4 . . . cord-334490-42gykxdx 17 1 Univ Univ NNP cord-334490-42gykxdx 17 2 . . . cord-334490-42gykxdx 18 1 Prof. Prof. NNP cord-334490-42gykxdx 18 2 Dr. Dr. NNP cord-334490-42gykxdx 18 3 J. J. NNP cord-334490-42gykxdx 18 4 Mascherbauer Mascherbauer NNP cord-334490-42gykxdx 18 5 ( ( -LRB- cord-334490-42gykxdx 18 6 ) ) -RRB- cord-334490-42gykxdx 18 7 Division Division NNP cord-334490-42gykxdx 18 8 of of IN cord-334490-42gykxdx 18 9 Cardiology Cardiology NNP cord-334490-42gykxdx 18 10 , , , cord-334490-42gykxdx 18 11 Department Department NNP cord-334490-42gykxdx 18 12 of of IN cord-334490-42gykxdx 18 13 Medicine Medicine NNP cord-334490-42gykxdx 18 14 II II NNP cord-334490-42gykxdx 18 15 , , , cord-334490-42gykxdx 18 16 Medical Medical NNP cord-334490-42gykxdx 18 17 University University NNP cord-334490-42gykxdx 18 18 of of IN cord-334490-42gykxdx 18 19 Vienna Vienna NNP cord-334490-42gykxdx 18 20 , , , cord-334490-42gykxdx 18 21 Waehringer Waehringer NNP cord-334490-42gykxdx 18 22 Guertel Guertel NNP cord-334490-42gykxdx 18 23 18 18 CD cord-334490-42gykxdx 18 24 - - SYM cord-334490-42gykxdx 18 25 20 20 CD cord-334490-42gykxdx 18 26 , , , cord-334490-42gykxdx 18 27 1090 1090 CD cord-334490-42gykxdx 18 28 Wien Wien NNP cord-334490-42gykxdx 18 29 , , , cord-334490-42gykxdx 18 30 Austria Austria NNP cord-334490-42gykxdx 18 31 julia.mascherbauer@meduniwien.ac.at julia.mascherbauer@meduniwien.ac.at NNP cord-334490-42gykxdx 18 32 arrhythmia arrhythmia NN cord-334490-42gykxdx 18 33 are be VBP cord-334490-42gykxdx 18 34 incompletely incompletely RB cord-334490-42gykxdx 18 35 understood understand VBN cord-334490-42gykxdx 18 36 but but CC cord-334490-42gykxdx 18 37 two two CD cord-334490-42gykxdx 18 38 main main JJ cord-334490-42gykxdx 18 39 theories theory NNS cord-334490-42gykxdx 18 40 prevail prevail VBP cord-334490-42gykxdx 18 41 . . . cord-334490-42gykxdx 19 1 Firstly firstly RB cord-334490-42gykxdx 19 2 , , , cord-334490-42gykxdx 19 3 elevated elevated JJ cord-334490-42gykxdx 19 4 troponin troponin JJ cord-334490-42gykxdx 19 5 levels level NNS cord-334490-42gykxdx 19 6 are be VBP cord-334490-42gykxdx 19 7 often often RB cord-334490-42gykxdx 19 8 observed observe VBN cord-334490-42gykxdx 19 9 in in IN cord-334490-42gykxdx 19 10 patients patient NNS cord-334490-42gykxdx 19 11 with with IN cord-334490-42gykxdx 19 12 critical critical JJ cord-334490-42gykxdx 19 13 illnesses illness NNS cord-334490-42gykxdx 19 14 and and CC cord-334490-42gykxdx 19 15 have have VBP cord-334490-42gykxdx 19 16 been be VBN cord-334490-42gykxdx 19 17 linked link VBN cord-334490-42gykxdx 19 18 to to IN cord-334490-42gykxdx 19 19 the the DT cord-334490-42gykxdx 19 20 systemic systemic JJ cord-334490-42gykxdx 19 21 inflammatory inflammatory JJ cord-334490-42gykxdx 19 22 state state NN cord-334490-42gykxdx 19 23 ( ( -LRB- cord-334490-42gykxdx 19 24 cytokine cytokine NN cord-334490-42gykxdx 19 25 storm storm NN cord-334490-42gykxdx 19 26 ) ) -RRB- cord-334490-42gykxdx 19 27 , , , cord-334490-42gykxdx 19 28 which which WDT cord-334490-42gykxdx 19 29 can can MD cord-334490-42gykxdx 19 30 involve involve VB cord-334490-42gykxdx 19 31 damage damage NN cord-334490-42gykxdx 19 32 to to IN cord-334490-42gykxdx 19 33 any any DT cord-334490-42gykxdx 19 34 organ organ NN cord-334490-42gykxdx 19 35 , , , cord-334490-42gykxdx 19 36 including include VBG cord-334490-42gykxdx 19 37 the the DT cord-334490-42gykxdx 19 38 heart heart NN cord-334490-42gykxdx 19 39 [ [ -LRB- cord-334490-42gykxdx 19 40 7 7 CD cord-334490-42gykxdx 19 41 ] ] -RRB- cord-334490-42gykxdx 19 42 . . . cord-334490-42gykxdx 20 1 Secondly secondly RB cord-334490-42gykxdx 20 2 , , , cord-334490-42gykxdx 20 3 viral viral JJ cord-334490-42gykxdx 20 4 diseases disease NNS cord-334490-42gykxdx 20 5 are be VBP cord-334490-42gykxdx 20 6 known know VBN cord-334490-42gykxdx 20 7 to to TO cord-334490-42gykxdx 20 8 potentially potentially RB cord-334490-42gykxdx 20 9 cause cause VB cord-334490-42gykxdx 20 10 myocardial myocardial JJ cord-334490-42gykxdx 20 11 inflammation inflammation NN cord-334490-42gykxdx 20 12 / / , cord-334490-42gykxdx 20 13 myocarditis myocarditis NN cord-334490-42gykxdx 20 14 [ [ -LRB- cord-334490-42gykxdx 20 15 8 8 CD cord-334490-42gykxdx 20 16 ] ] -RRB- cord-334490-42gykxdx 20 17 . . . cord-334490-42gykxdx 21 1 Indeed indeed RB cord-334490-42gykxdx 21 2 , , , cord-334490-42gykxdx 21 3 several several JJ cord-334490-42gykxdx 21 4 cases case NNS cord-334490-42gykxdx 21 5 of of IN cord-334490-42gykxdx 21 6 fulminant fulminant JJ cord-334490-42gykxdx 21 7 myocarditis myocarditis NN cord-334490-42gykxdx 21 8 in in IN cord-334490-42gykxdx 21 9 patients patient NNS cord-334490-42gykxdx 21 10 with with IN cord-334490-42gykxdx 21 11 COVID-19 COVID-19 NNP cord-334490-42gykxdx 21 12 have have VBP cord-334490-42gykxdx 21 13 been be VBN cord-334490-42gykxdx 21 14 reported report VBN cord-334490-42gykxdx 21 15 [ [ -LRB- cord-334490-42gykxdx 21 16 9 9 CD cord-334490-42gykxdx 21 17 ] ] -RRB- cord-334490-42gykxdx 21 18 ; ; : cord-334490-42gykxdx 21 19 however however RB cord-334490-42gykxdx 21 20 , , , cord-334490-42gykxdx 21 21 comprehensive comprehensive JJ cord-334490-42gykxdx 21 22 clinical clinical JJ cord-334490-42gykxdx 21 23 and and CC cord-334490-42gykxdx 21 24 imaging image VBG cord-334490-42gykxdx 21 25 work work NN cord-334490-42gykxdx 21 26 - - HYPH cord-334490-42gykxdx 21 27 up up NN cord-334490-42gykxdx 21 28 of of IN cord-334490-42gykxdx 21 29 these these DT cord-334490-42gykxdx 21 30 patients patient NNS cord-334490-42gykxdx 21 31 in in IN cord-334490-42gykxdx 21 32 prospective prospective JJ cord-334490-42gykxdx 21 33 cohorts cohort NNS cord-334490-42gykxdx 21 34 is be VBZ cord-334490-42gykxdx 21 35 lacking lack VBG cord-334490-42gykxdx 21 36 . . . cord-334490-42gykxdx 22 1 Frequently frequently RB cord-334490-42gykxdx 22 2 , , , cord-334490-42gykxdx 22 3 cardiologists cardiologist NNS cord-334490-42gykxdx 22 4 face face VBP cord-334490-42gykxdx 22 5 questions question NNS cord-334490-42gykxdx 22 6 by by IN cord-334490-42gykxdx 22 7 patients patient NNS cord-334490-42gykxdx 22 8 as as RB cord-334490-42gykxdx 22 9 well well RB cord-334490-42gykxdx 22 10 as as IN cord-334490-42gykxdx 22 11 other other JJ cord-334490-42gykxdx 22 12 healthcare healthcare NN cord-334490-42gykxdx 22 13 professionals professional NNS cord-334490-42gykxdx 22 14 about about IN cord-334490-42gykxdx 22 15 cardiovascular cardiovascular JJ cord-334490-42gykxdx 22 16 - - HYPH cord-334490-42gykxdx 22 17 specific specific JJ cord-334490-42gykxdx 22 18 aspects aspect NNS cord-334490-42gykxdx 22 19 of of IN cord-334490-42gykxdx 22 20 COVID-19 covid-19 NN cord-334490-42gykxdx 22 21 . . . cord-334490-42gykxdx 23 1 The the DT cord-334490-42gykxdx 23 2 intention intention NN cord-334490-42gykxdx 23 3 of of IN cord-334490-42gykxdx 23 4 this this DT cord-334490-42gykxdx 23 5 editorial editorial NN cord-334490-42gykxdx 23 6 is be VBZ cord-334490-42gykxdx 23 7 to to TO cord-334490-42gykxdx 23 8 provide provide VB cord-334490-42gykxdx 23 9 useful useful JJ cord-334490-42gykxdx 23 10 sources source NNS cord-334490-42gykxdx 23 11 with with IN cord-334490-42gykxdx 23 12 up up IN cord-334490-42gykxdx 23 13 to to IN cord-334490-42gykxdx 23 14 date date NN cord-334490-42gykxdx 23 15 information information NN cord-334490-42gykxdx 23 16 and and CC cord-334490-42gykxdx 23 17 discuss discuss VB cord-334490-42gykxdx 23 18 some some DT cord-334490-42gykxdx 23 19 of of IN cord-334490-42gykxdx 23 20 the the DT cord-334490-42gykxdx 23 21 most most RBS cord-334490-42gykxdx 23 22 frequently frequently RB cord-334490-42gykxdx 23 23 asked ask VBN cord-334490-42gykxdx 23 24 questions question NNS cord-334490-42gykxdx 23 25 . . . cord-334490-42gykxdx 24 1 The the DT cord-334490-42gykxdx 24 2 SARS SARS NNP cord-334490-42gykxdx 24 3 - - HYPH cord-334490-42gykxdx 24 4 CoV-2 CoV-2 NNP cord-334490-42gykxdx 24 5 enters enter VBZ cord-334490-42gykxdx 24 6 human human JJ cord-334490-42gykxdx 24 7 cells cell NNS cord-334490-42gykxdx 24 8 by by IN cord-334490-42gykxdx 24 9 binding bind VBG cord-334490-42gykxdx 24 10 to to IN cord-334490-42gykxdx 24 11 the the DT cord-334490-42gykxdx 24 12 angiotensin angiotensin NN cord-334490-42gykxdx 24 13 - - HYPH cord-334490-42gykxdx 24 14 converting convert VBG cord-334490-42gykxdx 24 15 enzyme enzyme NN cord-334490-42gykxdx 24 16 2 2 CD cord-334490-42gykxdx 24 17 ( ( -LRB- cord-334490-42gykxdx 24 18 ACE2 ACE2 NNP cord-334490-42gykxdx 24 19 ) ) -RRB- cord-334490-42gykxdx 24 20 receptor receptor NN cord-334490-42gykxdx 24 21 . . . cord-334490-42gykxdx 25 1 Concerns concern NNS cord-334490-42gykxdx 25 2 exist exist VBP cord-334490-42gykxdx 25 3 that that IN cord-334490-42gykxdx 25 4 ACE ace NN cord-334490-42gykxdx 25 5 inhibitors inhibitor NNS cord-334490-42gykxdx 25 6 ( ( -LRB- cord-334490-42gykxdx 25 7 ACE ace NN cord-334490-42gykxdx 25 8 - - HYPH cord-334490-42gykxdx 25 9 I I NNP cord-334490-42gykxdx 25 10 ) ) -RRB- cord-334490-42gykxdx 25 11 and and CC cord-334490-42gykxdx 25 12 angiotensin angiotensin NN cord-334490-42gykxdx 25 13 receptor receptor NN cord-334490-42gykxdx 25 14 blockers blocker NNS cord-334490-42gykxdx 25 15 ( ( -LRB- cord-334490-42gykxdx 25 16 ARB ARB NNP cord-334490-42gykxdx 25 17 ) ) -RRB- cord-334490-42gykxdx 25 18 may may MD cord-334490-42gykxdx 25 19 be be VB cord-334490-42gykxdx 25 20 harmful harmful JJ cord-334490-42gykxdx 25 21 due due IN cord-334490-42gykxdx 25 22 to to IN cord-334490-42gykxdx 25 23 an an DT cord-334490-42gykxdx 25 24 upregulation upregulation NN cord-334490-42gykxdx 25 25 of of IN cord-334490-42gykxdx 25 26 ACE2 ACE2 NNP cord-334490-42gykxdx 25 27 , , , cord-334490-42gykxdx 25 28 which which WDT cord-334490-42gykxdx 25 29 could could MD cord-334490-42gykxdx 25 30 facilitate facilitate VB cord-334490-42gykxdx 25 31 infections infection NNS cord-334490-42gykxdx 25 32 with with IN cord-334490-42gykxdx 25 33 SARS SARS NNP cord-334490-42gykxdx 25 34 - - HYPH cord-334490-42gykxdx 25 35 CoV-2 CoV-2 NNP cord-334490-42gykxdx 25 36 or or CC cord-334490-42gykxdx 25 37 increase increase VB cord-334490-42gykxdx 25 38 disease disease NN cord-334490-42gykxdx 25 39 severity severity NN cord-334490-42gykxdx 25 40 [ [ -LRB- cord-334490-42gykxdx 25 41 10 10 CD cord-334490-42gykxdx 25 42 ] ] -RRB- cord-334490-42gykxdx 25 43 . . . cord-334490-42gykxdx 26 1 Given give VBN cord-334490-42gykxdx 26 2 the the DT cord-334490-42gykxdx 26 3 frequent frequent JJ cord-334490-42gykxdx 26 4 use use NN cord-334490-42gykxdx 26 5 of of IN cord-334490-42gykxdx 26 6 ACE ace NN cord-334490-42gykxdx 26 7 - - HYPH cord-334490-42gykxdx 26 8 I I NNP cord-334490-42gykxdx 26 9 and and CC cord-334490-42gykxdx 26 10 ARB ARB NNP cord-334490-42gykxdx 26 11 in in IN cord-334490-42gykxdx 26 12 patients patient NNS cord-334490-42gykxdx 26 13 suffering suffer VBG cord-334490-42gykxdx 26 14 from from IN cord-334490-42gykxdx 26 15 hypertension hypertension NN cord-334490-42gykxdx 26 16 , , , cord-334490-42gykxdx 26 17 coronary coronary JJ cord-334490-42gykxdx 26 18 artery artery NN cord-334490-42gykxdx 26 19 disease disease NN cord-334490-42gykxdx 26 20 , , , cord-334490-42gykxdx 26 21 heart heart NN cord-334490-42gykxdx 26 22 failure failure NN cord-334490-42gykxdx 26 23 , , , cord-334490-42gykxdx 26 24 and and CC cord-334490-42gykxdx 26 25 chronic chronic JJ cord-334490-42gykxdx 26 26 kidney kidney NN cord-334490-42gykxdx 26 27 disease disease NN cord-334490-42gykxdx 26 28 , , , cord-334490-42gykxdx 26 29 such such JJ cord-334490-42gykxdx 26 30 considerations consideration NNS cord-334490-42gykxdx 26 31 lead lead VBP cord-334490-42gykxdx 26 32 to to IN cord-334490-42gykxdx 26 33 great great JJ cord-334490-42gykxdx 26 34 uncertainty uncertainty NN cord-334490-42gykxdx 26 35 among among IN cord-334490-42gykxdx 26 36 patients patient NNS cord-334490-42gykxdx 26 37 and and CC cord-334490-42gykxdx 26 38 physicians physician NNS cord-334490-42gykxdx 26 39 . . . cord-334490-42gykxdx 27 1 In in IN cord-334490-42gykxdx 27 2 addition addition NN cord-334490-42gykxdx 27 3 , , , cord-334490-42gykxdx 27 4 early early JJ cord-334490-42gykxdx 27 5 observational observational JJ cord-334490-42gykxdx 27 6 data datum NNS cord-334490-42gykxdx 27 7 reported report VBD cord-334490-42gykxdx 27 8 that that IN cord-334490-42gykxdx 27 9 patients patient NNS cord-334490-42gykxdx 27 10 taking take VBG cord-334490-42gykxdx 27 11 ACE ace NN cord-334490-42gykxdx 27 12 - - HYPH cord-334490-42gykxdx 27 13 I I NNP cord-334490-42gykxdx 27 14 and and CC cord-334490-42gykxdx 27 15 ARB ARB NNP cord-334490-42gykxdx 27 16 were be VBD cord-334490-42gykxdx 27 17 at at IN cord-334490-42gykxdx 27 18 higher high JJR cord-334490-42gykxdx 27 19 risk risk NN cord-334490-42gykxdx 27 20 for for IN cord-334490-42gykxdx 27 21 a a DT cord-334490-42gykxdx 27 22 dismal dismal JJ cord-334490-42gykxdx 27 23 outcome outcome NN cord-334490-42gykxdx 27 24 in in IN cord-334490-42gykxdx 27 25 COVID-19 COVID-19 NNP cord-334490-42gykxdx 27 26 [ [ -LRB- cord-334490-42gykxdx 27 27 11 11 CD cord-334490-42gykxdx 27 28 ] ] -RRB- cord-334490-42gykxdx 27 29 ; ; : cord-334490-42gykxdx 27 30 however however RB cord-334490-42gykxdx 27 31 , , , cord-334490-42gykxdx 27 32 these these DT cord-334490-42gykxdx 27 33 early early JJ cord-334490-42gykxdx 27 34 reports report NNS cord-334490-42gykxdx 27 35 did do VBD cord-334490-42gykxdx 27 36 not not RB cord-334490-42gykxdx 27 37 take take VB cord-334490-42gykxdx 27 38 into into IN cord-334490-42gykxdx 27 39 account account NN cord-334490-42gykxdx 27 40 the the DT cord-334490-42gykxdx 27 41 higher high JJR cord-334490-42gykxdx 27 42 risk risk NN cord-334490-42gykxdx 27 43 profile profile NN cord-334490-42gykxdx 27 44 which which WDT cord-334490-42gykxdx 27 45 we -PRON- PRP cord-334490-42gykxdx 27 46 expect expect VBP cord-334490-42gykxdx 27 47 in in IN cord-334490-42gykxdx 27 48 patients patient NNS cord-334490-42gykxdx 27 49 taking take VBG cord-334490-42gykxdx 27 50 ACE ace NN cord-334490-42gykxdx 27 51 - - HYPH cord-334490-42gykxdx 27 52 I I NNP cord-334490-42gykxdx 27 53 and and CC cord-334490-42gykxdx 27 54 ARB ARB NNP cord-334490-42gykxdx 27 55 as as IN cord-334490-42gykxdx 27 56 compared compare VBN cord-334490-42gykxdx 27 57 to to IN cord-334490-42gykxdx 27 58 those those DT cord-334490-42gykxdx 27 59 having have VBG cord-334490-42gykxdx 27 60 no no DT cord-334490-42gykxdx 27 61 previous previous JJ cord-334490-42gykxdx 27 62 medication medication NN cord-334490-42gykxdx 27 63 . . . cord-334490-42gykxdx 28 1 Conversely conversely RB cord-334490-42gykxdx 28 2 , , , cord-334490-42gykxdx 28 3 some some DT cord-334490-42gykxdx 28 4 animal animal NN cord-334490-42gykxdx 28 5 models model NNS cord-334490-42gykxdx 28 6 sug sug NNP cord-334490-42gykxdx 28 7 - - HYPH cord-334490-42gykxdx 28 8 gested geste VBD cord-334490-42gykxdx 28 9 a a DT cord-334490-42gykxdx 28 10 protective protective JJ cord-334490-42gykxdx 28 11 effect effect NN cord-334490-42gykxdx 28 12 of of IN cord-334490-42gykxdx 28 13 ACE ace NN cord-334490-42gykxdx 28 14 - - HYPH cord-334490-42gykxdx 28 15 I I NNP cord-334490-42gykxdx 28 16 and and CC cord-334490-42gykxdx 28 17 ARB ARB NNP cord-334490-42gykxdx 28 18 in in IN cord-334490-42gykxdx 28 19 acute acute JJ cord-334490-42gykxdx 28 20 lung lung NN cord-334490-42gykxdx 28 21 injury injury NN cord-334490-42gykxdx 28 22 [ [ -LRB- cord-334490-42gykxdx 28 23 12 12 CD cord-334490-42gykxdx 28 24 , , , cord-334490-42gykxdx 28 25 13 13 CD cord-334490-42gykxdx 28 26 ] ] -RRB- cord-334490-42gykxdx 28 27 . . . cord-334490-42gykxdx 29 1 Several several JJ cord-334490-42gykxdx 29 2 retrospective retrospective JJ cord-334490-42gykxdx 29 3 studies study NNS cord-334490-42gykxdx 29 4 reported report VBD cord-334490-42gykxdx 29 5 that that IN cord-334490-42gykxdx 29 6 patients patient NNS cord-334490-42gykxdx 29 7 with with IN cord-334490-42gykxdx 29 8 COVID-19 covid-19 JJ cord-334490-42gykxdx 29 9 taking take VBG cord-334490-42gykxdx 29 10 ACE ace NN cord-334490-42gykxdx 29 11 - - HYPH cord-334490-42gykxdx 29 12 I I NNP cord-334490-42gykxdx 29 13 or or CC cord-334490-42gykxdx 29 14 ARB ARB NNP cord-334490-42gykxdx 29 15 were be VBD cord-334490-42gykxdx 29 16 at at IN cord-334490-42gykxdx 29 17 lower low JJR cord-334490-42gykxdx 29 18 risk risk NN cord-334490-42gykxdx 29 19 for for IN cord-334490-42gykxdx 29 20 mortality mortality NN cord-334490-42gykxdx 29 21 compared compare VBN cord-334490-42gykxdx 29 22 to to IN cord-334490-42gykxdx 29 23 patients patient NNS cord-334490-42gykxdx 29 24 without without IN cord-334490-42gykxdx 29 25 ACE ace NN cord-334490-42gykxdx 29 26 - - HYPH cord-334490-42gykxdx 29 27 I I NNP cord-334490-42gykxdx 29 28 or or CC cord-334490-42gykxdx 29 29 ARB ARB NNP cord-334490-42gykxdx 29 30 in in IN cord-334490-42gykxdx 29 31 adjusted adjust VBN cord-334490-42gykxdx 29 32 models model NNS cord-334490-42gykxdx 29 33 [ [ -LRB- cord-334490-42gykxdx 29 34 14 14 CD cord-334490-42gykxdx 29 35 , , , cord-334490-42gykxdx 29 36 15 15 CD cord-334490-42gykxdx 29 37 ] ] -RRB- cord-334490-42gykxdx 29 38 . . . cord-334490-42gykxdx 30 1 Dozens dozen NNS cord-334490-42gykxdx 30 2 of of IN cord-334490-42gykxdx 30 3 prospective prospective JJ cord-334490-42gykxdx 30 4 trials trial NNS cord-334490-42gykxdx 30 5 randomizing randomize VBG cord-334490-42gykxdx 30 6 patients patient NNS cord-334490-42gykxdx 30 7 with with IN cord-334490-42gykxdx 30 8 COVID-19 covid-19 CD cord-334490-42gykxdx 30 9 to to IN cord-334490-42gykxdx 30 10 either either CC cord-334490-42gykxdx 30 11 ACE ace NN cord-334490-42gykxdx 30 12 - - HYPH cord-334490-42gykxdx 30 13 I I NNP cord-334490-42gykxdx 30 14 and and CC cord-334490-42gykxdx 30 15 ARB ARB NNP cord-334490-42gykxdx 30 16 or or CC cord-334490-42gykxdx 30 17 placebo placebo NN cord-334490-42gykxdx 30 18 are be VBP cord-334490-42gykxdx 30 19 currently currently RB cord-334490-42gykxdx 30 20 ongoing ongoing JJ cord-334490-42gykxdx 30 21 , , , cord-334490-42gykxdx 30 22 which which WDT cord-334490-42gykxdx 30 23 will will MD cord-334490-42gykxdx 30 24 augment augment VB cord-334490-42gykxdx 30 25 our -PRON- PRP$ cord-334490-42gykxdx 30 26 knowledge knowledge NN cord-334490-42gykxdx 30 27 on on IN cord-334490-42gykxdx 30 28 potential potential JJ cord-334490-42gykxdx 30 29 benefits benefit NNS cord-334490-42gykxdx 30 30 and and CC cord-334490-42gykxdx 30 31 harms harm NNS cord-334490-42gykxdx 30 32 of of IN cord-334490-42gykxdx 30 33 ACE ace NN cord-334490-42gykxdx 30 34 - - HYPH cord-334490-42gykxdx 30 35 I I NNP cord-334490-42gykxdx 30 36 and and CC cord-334490-42gykxdx 30 37 ARB ARB NNP cord-334490-42gykxdx 30 38 in in IN cord-334490-42gykxdx 30 39 COVID-19 COVID-19 NNP cord-334490-42gykxdx 30 40 . . . cord-334490-42gykxdx 31 1 As as IN cord-334490-42gykxdx 31 2 of of IN cord-334490-42gykxdx 31 3 June June NNP cord-334490-42gykxdx 31 4 2020 2020 CD cord-334490-42gykxdx 31 5 , , , cord-334490-42gykxdx 31 6 all all DT cord-334490-42gykxdx 31 7 major major JJ cord-334490-42gykxdx 31 8 cardiovascular cardiovascular JJ cord-334490-42gykxdx 31 9 scientific scientific JJ cord-334490-42gykxdx 31 10 organizations organization NNS cord-334490-42gykxdx 31 11 and and CC cord-334490-42gykxdx 31 12 official official JJ cord-334490-42gykxdx 31 13 health health NN cord-334490-42gykxdx 31 14 regulatory regulatory JJ cord-334490-42gykxdx 31 15 bodies body NNS cord-334490-42gykxdx 31 16 recommend recommend VBP cord-334490-42gykxdx 31 17 not not RB cord-334490-42gykxdx 31 18 to to TO cord-334490-42gykxdx 31 19 discontinue discontinue VB cord-334490-42gykxdx 31 20 ACE ace NN cord-334490-42gykxdx 31 21 - - HYPH cord-334490-42gykxdx 31 22 I I NNP cord-334490-42gykxdx 31 23 and and CC cord-334490-42gykxdx 31 24 ARB ARB NNP cord-334490-42gykxdx 31 25 in in IN cord-334490-42gykxdx 31 26 patients patient NNS cord-334490-42gykxdx 31 27 with with IN cord-334490-42gykxdx 31 28 COVID-19 COVID-19 NNP cord-334490-42gykxdx 31 29 [ [ -LRB- cord-334490-42gykxdx 31 30 16 16 CD cord-334490-42gykxdx 31 31 , , , cord-334490-42gykxdx 31 32 17 17 CD cord-334490-42gykxdx 31 33 ] ] -RRB- cord-334490-42gykxdx 31 34 . . . cord-334490-42gykxdx 32 1 A a DT cord-334490-42gykxdx 32 2 beneficial beneficial JJ cord-334490-42gykxdx 32 3 effect effect NN cord-334490-42gykxdx 32 4 , , , cord-334490-42gykxdx 32 5 however however RB cord-334490-42gykxdx 32 6 , , , cord-334490-42gykxdx 32 7 remains remain VBZ cord-334490-42gykxdx 32 8 uncertain uncertain JJ cord-334490-42gykxdx 32 9 and and CC cord-334490-42gykxdx 32 10 ACE ace NN cord-334490-42gykxdx 32 11 - - HYPH cord-334490-42gykxdx 32 12 I I NNP cord-334490-42gykxdx 32 13 and and CC cord-334490-42gykxdx 32 14 ARB ARB NNP cord-334490-42gykxdx 32 15 should should MD cord-334490-42gykxdx 32 16 not not RB cord-334490-42gykxdx 32 17 be be VB cord-334490-42gykxdx 32 18 used use VBN cord-334490-42gykxdx 32 19 as as IN cord-334490-42gykxdx 32 20 treatment treatment NN cord-334490-42gykxdx 32 21 for for IN cord-334490-42gykxdx 32 22 COVID-19 covid-19 JJ cord-334490-42gykxdx 32 23 outside outside RB cord-334490-42gykxdx 32 24 of of IN cord-334490-42gykxdx 32 25 the the DT cord-334490-42gykxdx 32 26 setting setting NN cord-334490-42gykxdx 32 27 of of IN cord-334490-42gykxdx 32 28 clinical clinical JJ cord-334490-42gykxdx 32 29 trials trial NNS cord-334490-42gykxdx 32 30 [ [ -LRB- cord-334490-42gykxdx 32 31 18 18 CD cord-334490-42gykxdx 32 32 ] ] -RRB- cord-334490-42gykxdx 32 33 . . . cord-334490-42gykxdx 33 1 Updated update VBN cord-334490-42gykxdx 33 2 information information NN cord-334490-42gykxdx 33 3 may may MD cord-334490-42gykxdx 33 4 be be VB cord-334490-42gykxdx 33 5 found find VBN cord-334490-42gykxdx 33 6 under under IN cord-334490-42gykxdx 33 7 : : : cord-334490-42gykxdx 33 8 https:// https:// NN cord-334490-42gykxdx 33 9 www.covid19treatmentguidelines.nih.gov/concomita www.covid19treatmentguidelines.nih.gov/concomita ADD cord-334490-42gykxdx 33 10 nt nt RB cord-334490-42gykxdx 33 11 - - HYPH cord-334490-42gykxdx 33 12 medications/. medications/. JJ cord-334490-42gykxdx 33 13 ( ( -LRB- cord-334490-42gykxdx 33 14 2 2 CD cord-334490-42gykxdx 33 15 ) ) -RRB- cord-334490-42gykxdx 34 1 My -PRON- PRP$ cord-334490-42gykxdx 34 2 patient patient NN cord-334490-42gykxdx 34 3 with with IN cord-334490-42gykxdx 34 4 COVID-19 COVID-19 NNP cord-334490-42gykxdx 34 5 has have VBZ cord-334490-42gykxdx 34 6 elevated elevate VBN cord-334490-42gykxdx 34 7 troponin troponin JJ cord-334490-42gykxdx 34 8 levels- levels- JJ cord-334490-42gykxdx 35 1 What what WP cord-334490-42gykxdx 35 2 now now RB cord-334490-42gykxdx 35 3 ? ? . cord-334490-42gykxdx 36 1 Cardiac cardiac JJ cord-334490-42gykxdx 36 2 injury injury NN cord-334490-42gykxdx 36 3 , , , cord-334490-42gykxdx 36 4 defined define VBN cord-334490-42gykxdx 36 5 as as IN cord-334490-42gykxdx 36 6 elevated elevated JJ cord-334490-42gykxdx 36 7 troponin troponin JJ cord-334490-42gykxdx 36 8 levels level NNS cord-334490-42gykxdx 36 9 , , , cord-334490-42gykxdx 36 10 is be VBZ cord-334490-42gykxdx 36 11 frequently frequently RB cord-334490-42gykxdx 36 12 observed observe VBN cord-334490-42gykxdx 36 13 in in IN cord-334490-42gykxdx 36 14 patients patient NNS cord-334490-42gykxdx 36 15 with with IN cord-334490-42gykxdx 36 16 COVID-19 COVID-19 NNP cord-334490-42gykxdx 36 17 . . . cord-334490-42gykxdx 37 1 Potential potential JJ cord-334490-42gykxdx 37 2 mechanisms mechanism NNS cord-334490-42gykxdx 37 3 include include VBP cord-334490-42gykxdx 37 4 type type NN cord-334490-42gykxdx 37 5 I -PRON- PRP cord-334490-42gykxdx 37 6 and and CC cord-334490-42gykxdx 37 7 type type NN cord-334490-42gykxdx 37 8 II ii CD cord-334490-42gykxdx 37 9 myocardial myocardial JJ cord-334490-42gykxdx 37 10 infarction infarction NN cord-334490-42gykxdx 37 11 ( ( -LRB- cord-334490-42gykxdx 37 12 MI MI NNP cord-334490-42gykxdx 37 13 ) ) -RRB- cord-334490-42gykxdx 37 14 , , , cord-334490-42gykxdx 37 15 Takotsubo Takotsubo NNP cord-334490-42gykxdx 37 16 syndrome syndrome NN cord-334490-42gykxdx 37 17 , , , cord-334490-42gykxdx 37 18 shock shock NN cord-334490-42gykxdx 37 19 as as IN cord-334490-42gykxdx 37 20 part part NN cord-334490-42gykxdx 37 21 of of IN cord-334490-42gykxdx 37 22 COVID-19 COVID-19 NNP cord-334490-42gykxdx 37 23 , , , cord-334490-42gykxdx 37 24 myocarditis myocarditis NN cord-334490-42gykxdx 37 25 with with IN cord-334490-42gykxdx 37 26 direct direct JJ cord-334490-42gykxdx 37 27 viral viral JJ cord-334490-42gykxdx 37 28 and and CC cord-334490-42gykxdx 37 29 cytopathic cytopathic JJ cord-334490-42gykxdx 37 30 effects effect NNS cord-334490-42gykxdx 37 31 , , , cord-334490-42gykxdx 37 32 and and CC cord-334490-42gykxdx 37 33 cytokine cytokine NN cord-334490-42gykxdx 37 34 release release NN cord-334490-42gykxdx 37 35 syndrome syndrome NN cord-334490-42gykxdx 37 36 [ [ -LRB- cord-334490-42gykxdx 37 37 19 19 CD cord-334490-42gykxdx 37 38 ] ] -RRB- cord-334490-42gykxdx 37 39 . . . cord-334490-42gykxdx 38 1 The the DT cord-334490-42gykxdx 38 2 European European NNP cord-334490-42gykxdx 38 3 Association Association NNP cord-334490-42gykxdx 38 4 of of IN cord-334490-42gykxdx 38 5 Percutaneous Percutaneous NNP cord-334490-42gykxdx 38 6 Cardiovascular Cardiovascular NNP cord-334490-42gykxdx 38 7 Interventions Interventions NNPS cord-334490-42gykxdx 38 8 ( ( -LRB- cord-334490-42gykxdx 38 9 EAPCI EAPCI NNP cord-334490-42gykxdx 38 10 ) ) -RRB- cord-334490-42gykxdx 38 11 issued issue VBD cord-334490-42gykxdx 38 12 a a DT cord-334490-42gykxdx 38 13 position position NN cord-334490-42gykxdx 38 14 statement statement NN cord-334490-42gykxdx 38 15 on on IN cord-334490-42gykxdx 38 16 invasive invasive JJ cord-334490-42gykxdx 38 17 management management NN cord-334490-42gykxdx 38 18 in in IN cord-334490-42gykxdx 38 19 patients patient NNS cord-334490-42gykxdx 38 20 with with IN cord-334490-42gykxdx 38 21 ACS ACS NNP cord-334490-42gykxdx 38 22 during during IN cord-334490-42gykxdx 38 23 the the DT cord-334490-42gykxdx 38 24 COVID-19 covid-19 JJ cord-334490-42gykxdx 38 25 pandemic pandemic NN cord-334490-42gykxdx 38 26 [ [ -LRB- cord-334490-42gykxdx 38 27 19 19 CD cord-334490-42gykxdx 38 28 ] ] -RRB- cord-334490-42gykxdx 38 29 . . . cord-334490-42gykxdx 39 1 The the DT cord-334490-42gykxdx 39 2 EAPCI EAPCI NNP cord-334490-42gykxdx 39 3 recommends recommend VBZ cord-334490-42gykxdx 39 4 that that IN cord-334490-42gykxdx 39 5 in in IN cord-334490-42gykxdx 39 6 cases case NNS cord-334490-42gykxdx 39 7 of of IN cord-334490-42gykxdx 39 8 mild mild JJ cord-334490-42gykxdx 39 9 troponin troponin JJ cord-334490-42gykxdx 39 10 elevation elevation NN cord-334490-42gykxdx 39 11 ( ( -LRB- cord-334490-42gykxdx 39 12 < < NNP cord-334490-42gykxdx 39 13 2 2 CD cord-334490-42gykxdx 39 14 - - SYM cord-334490-42gykxdx 39 15 3 3 CD cord-334490-42gykxdx 39 16 times time NNS cord-334490-42gykxdx 39 17 the the DT cord-334490-42gykxdx 39 18 upper upper JJ cord-334490-42gykxdx 39 19 limit limit NN cord-334490-42gykxdx 39 20 of of IN cord-334490-42gykxdx 39 21 normal normal JJ cord-334490-42gykxdx 39 22 ) ) -RRB- cord-334490-42gykxdx 39 23 , , , cord-334490-42gykxdx 39 24 particularly particularly RB cord-334490-42gykxdx 39 25 in in IN cord-334490-42gykxdx 39 26 older old JJR cord-334490-42gykxdx 39 27 patients patient NNS cord-334490-42gykxdx 39 28 with with IN cord-334490-42gykxdx 39 29 pre pre JJ cord-334490-42gykxdx 39 30 - - JJ cord-334490-42gykxdx 39 31 existing existing JJ cord-334490-42gykxdx 39 32 cardiac cardiac JJ cord-334490-42gykxdx 39 33 conditions condition NNS cord-334490-42gykxdx 39 34 , , , cord-334490-42gykxdx 39 35 a a DT cord-334490-42gykxdx 39 36 work work NN cord-334490-42gykxdx 39 37 - - HYPH cord-334490-42gykxdx 39 38 up up NN cord-334490-42gykxdx 39 39 for for IN cord-334490-42gykxdx 39 40 type type NN cord-334490-42gykxdx 39 41 1 1 CD cord-334490-42gykxdx 39 42 MI MI NNP cord-334490-42gykxdx 39 43 is be VBZ cord-334490-42gykxdx 39 44 not not RB cord-334490-42gykxdx 39 45 indicated indicate VBN cord-334490-42gykxdx 39 46 , , , cord-334490-42gykxdx 39 47 unless unless IN cord-334490-42gykxdx 39 48 strongly strongly RB cord-334490-42gykxdx 39 49 indicated indicate VBN cord-334490-42gykxdx 39 50 by by IN cord-334490-42gykxdx 39 51 clinical clinical JJ cord-334490-42gykxdx 39 52 presentation presentation NN cord-334490-42gykxdx 39 53 and and CC cord-334490-42gykxdx 39 54 electrocardiograph electrocardiograph NN cord-334490-42gykxdx 39 55 ( ( -LRB- cord-334490-42gykxdx 39 56 ECG ECG NNP cord-334490-42gykxdx 39 57 ) ) -RRB- cord-334490-42gykxdx 39 58 findings finding NNS cord-334490-42gykxdx 39 59 . . . cord-334490-42gykxdx 40 1 Marked marked JJ cord-334490-42gykxdx 40 2 elevations elevation NNS cord-334490-42gykxdx 40 3 in in IN cord-334490-42gykxdx 40 4 cardiac cardiac JJ cord-334490-42gykxdx 40 5 troponin troponin JJ cord-334490-42gykxdx 40 6 levels level NNS cord-334490-42gykxdx 40 7 ( ( -LRB- cord-334490-42gykxdx 40 8 e.g. e.g. RB cord-334490-42gykxdx 40 9 > > XX cord-334490-42gykxdx 40 10 5 5 CD cord-334490-42gykxdx 40 11 times time NNS cord-334490-42gykxdx 40 12 the the DT cord-334490-42gykxdx 40 13 upper upper JJ cord-334490-42gykxdx 40 14 limit limit NN cord-334490-42gykxdx 40 15 of of IN cord-334490-42gykxdx 40 16 normal normal JJ cord-334490-42gykxdx 40 17 ) ) -RRB- cord-334490-42gykxdx 40 18 may may MD cord-334490-42gykxdx 40 19 be be VB cord-334490-42gykxdx 40 20 found find VBN cord-334490-42gykxdx 40 21 in in IN cord-334490-42gykxdx 40 22 acute acute JJ cord-334490-42gykxdx 40 23 respiratory respiratory JJ cord-334490-42gykxdx 40 24 syndrome syndrome NN cord-334490-42gykxdx 40 25 , , , cord-334490-42gykxdx 40 26 tachycardia tachycardia NN cord-334490-42gykxdx 40 27 , , , cord-334490-42gykxdx 40 28 systemic systemic JJ cord-334490-42gykxdx 40 29 hypoxemia hypoxemia NN cord-334490-42gykxdx 40 30 , , , cord-334490-42gykxdx 40 31 shock shock NN cord-334490-42gykxdx 40 32 as as IN cord-334490-42gykxdx 40 33 part part NN cord-334490-42gykxdx 40 34 of of IN cord-334490-42gykxdx 40 35 COVID-19 COVID-19 NNP cord-334490-42gykxdx 40 36 , , , cord-334490-42gykxdx 40 37 myocarditis myocarditis NN cord-334490-42gykxdx 40 38 , , , cord-334490-42gykxdx 40 39 Takotsubo Takotsubo NNP cord-334490-42gykxdx 40 40 syndrome syndrome NN cord-334490-42gykxdx 40 41 , , , cord-334490-42gykxdx 40 42 or or CC cord-334490-42gykxdx 40 43 type type NN cord-334490-42gykxdx 40 44 1 1 CD cord-334490-42gykxdx 40 45 MI MI NNP cord-334490-42gykxdx 40 46 triggered trigger VBN cord-334490-42gykxdx 40 47 by by IN cord-334490-42gykxdx 40 48 COVID-19 COVID-19 NNP cord-334490-42gykxdx 40 49 . . . cord-334490-42gykxdx 41 1 If if IN cord-334490-42gykxdx 41 2 symptoms symptom NNS cord-334490-42gykxdx 41 3 and and CC cord-334490-42gykxdx 41 4 ECG ECG NNP cord-334490-42gykxdx 41 5 findings finding NNS cord-334490-42gykxdx 41 6 are be VBP cord-334490-42gykxdx 41 7 not not RB cord-334490-42gykxdx 41 8 suggestive suggestive JJ cord-334490-42gykxdx 41 9 of of IN cord-334490-42gykxdx 41 10 type type NN cord-334490-42gykxdx 41 11 1 1 CD cord-334490-42gykxdx 41 12 MI MI NNP cord-334490-42gykxdx 41 13 , , , cord-334490-42gykxdx 41 14 the the DT cord-334490-42gykxdx 41 15 EAPCI EAPCI NNP cord-334490-42gykxdx 41 16 recommends recommend VBZ cord-334490-42gykxdx 41 17 that that IN cord-334490-42gykxdx 41 18 echocardiographic echocardiographic JJ cord-334490-42gykxdx 41 19 work work NN cord-334490-42gykxdx 41 20 - - HYPH cord-334490-42gykxdx 41 21 up up NN cord-334490-42gykxdx 41 22 should should MD cord-334490-42gykxdx 41 23 be be VB cord-334490-42gykxdx 41 24 considered consider VBN cord-334490-42gykxdx 41 25 in in IN cord-334490-42gykxdx 41 26 order order NN cord-334490-42gykxdx 41 27 to to TO cord-334490-42gykxdx 41 28 help help VB cord-334490-42gykxdx 41 29 diagnose diagnose VB cord-334490-42gykxdx 41 30 the the DT cord-334490-42gykxdx 41 31 underlying underlie VBG cord-334490-42gykxdx 41 32 cause cause NN cord-334490-42gykxdx 41 33 [ [ -LRB- cord-334490-42gykxdx 41 34 19 19 CD cord-334490-42gykxdx 41 35 ] ] -RRB- cord-334490-42gykxdx 41 36 . . . cord-334490-42gykxdx 42 1 Percutaneous percutaneous JJ cord-334490-42gykxdx 42 2 coronary coronary NN cord-334490-42gykxdx 42 3 intervention intervention NN cord-334490-42gykxdx 42 4 ( ( -LRB- cord-334490-42gykxdx 42 5 PCI PCI NNP cord-334490-42gykxdx 42 6 ) ) -RRB- cord-334490-42gykxdx 42 7 centers center NNS cord-334490-42gykxdx 42 8 have have VBP cord-334490-42gykxdx 42 9 incorporated incorporate VBN cord-334490-42gykxdx 42 10 COVID-19-specific COVID-19-specific NNP cord-334490-42gykxdx 42 11 triage triage NN cord-334490-42gykxdx 42 12 systems system NNS cord-334490-42gykxdx 42 13 , , , cord-334490-42gykxdx 42 14 in in IN cord-334490-42gykxdx 42 15 accordance accordance NN cord-334490-42gykxdx 42 16 with with IN cord-334490-42gykxdx 42 17 local local JJ cord-334490-42gykxdx 42 18 regulations regulation NNS cord-334490-42gykxdx 42 19 and and CC cord-334490-42gykxdx 42 20 advisory advisory JJ cord-334490-42gykxdx 42 21 statements statement NNS cord-334490-42gykxdx 42 22 . . . cord-334490-42gykxdx 43 1 Concerns concern NNS cord-334490-42gykxdx 43 2 exist exist VBP cord-334490-42gykxdx 43 3 that that IN cord-334490-42gykxdx 43 4 patients patient NNS cord-334490-42gykxdx 43 5 with with IN cord-334490-42gykxdx 43 6 ACS ACS NNP cord-334490-42gykxdx 43 7 may may MD cord-334490-42gykxdx 43 8 not not RB cord-334490-42gykxdx 43 9 attend attend VB cord-334490-42gykxdx 43 10 medical medical JJ cord-334490-42gykxdx 43 11 services service NNS cord-334490-42gykxdx 43 12 due due JJ cord-334490-42gykxdx 43 13 to to IN cord-334490-42gykxdx 43 14 fear fear NN cord-334490-42gykxdx 43 15 of of IN cord-334490-42gykxdx 43 16 an an DT cord-334490-42gykxdx 43 17 infection infection NN cord-334490-42gykxdx 43 18 with with IN cord-334490-42gykxdx 43 19 SARS SARS NNP cord-334490-42gykxdx 43 20 - - HYPH cord-334490-42gykxdx 43 21 Cov-2 Cov-2 NNP cord-334490-42gykxdx 43 22 . . . cord-334490-42gykxdx 44 1 Indeed indeed RB cord-334490-42gykxdx 44 2 , , , cord-334490-42gykxdx 44 3 studies study NNS cord-334490-42gykxdx 44 4 demonstrated demonstrate VBD cord-334490-42gykxdx 44 5 a a DT cord-334490-42gykxdx 44 6 40 40 CD cord-334490-42gykxdx 44 7 % % NN cord-334490-42gykxdx 44 8 drop drop NN cord-334490-42gykxdx 44 9 in in IN cord-334490-42gykxdx 44 10 ST ST NNP cord-334490-42gykxdx 44 11 - - HYPH cord-334490-42gykxdx 44 12 elevation elevation NNP cord-334490-42gykxdx 44 13 myocardial myocardial JJ cord-334490-42gykxdx 44 14 infarction infarction NN cord-334490-42gykxdx 44 15 ( ( -LRB- cord-334490-42gykxdx 44 16 STEMI STEMI NNP cord-334490-42gykxdx 44 17 ) ) -RRB- cord-334490-42gykxdx 44 18 activations activation NNS cord-334490-42gykxdx 44 19 in in IN cord-334490-42gykxdx 44 20 PCI pci NN cord-334490-42gykxdx 44 21 centers center NNS cord-334490-42gykxdx 44 22 [ [ -LRB- cord-334490-42gykxdx 44 23 20 20 CD cord-334490-42gykxdx 44 24 ] ] -RRB- cord-334490-42gykxdx 44 25 . . . cord-334490-42gykxdx 45 1 Patients patient NNS cord-334490-42gykxdx 45 2 and and CC cord-334490-42gykxdx 45 3 healthcare healthcare NN cord-334490-42gykxdx 45 4 professionals professional NNS cord-334490-42gykxdx 45 5 should should MD cord-334490-42gykxdx 45 6 be be VB cord-334490-42gykxdx 45 7 encouraged encourage VBN cord-334490-42gykxdx 45 8 to to TO cord-334490-42gykxdx 45 9 not not RB cord-334490-42gykxdx 45 10 delay delay VB cord-334490-42gykxdx 45 11 consultation consultation NN cord-334490-42gykxdx 45 12 of of IN cord-334490-42gykxdx 45 13 PCI pci NN cord-334490-42gykxdx 45 14 centers center NNS cord-334490-42gykxdx 45 15 if if IN cord-334490-42gykxdx 45 16 symptoms symptom NNS cord-334490-42gykxdx 45 17 are be VBP cord-334490-42gykxdx 45 18 suggestive suggestive JJ cord-334490-42gykxdx 45 19 of of IN cord-334490-42gykxdx 45 20 ACS ACS NNP cord-334490-42gykxdx 45 21 . . . cord-334490-42gykxdx 46 1 Of of IN cord-334490-42gykxdx 46 2 note note NN cord-334490-42gykxdx 46 3 , , , cord-334490-42gykxdx 46 4 several several JJ cord-334490-42gykxdx 46 5 antiviral antiviral JJ cord-334490-42gykxdx 46 6 drugs drug NNS cord-334490-42gykxdx 46 7 investigated investigate VBN cord-334490-42gykxdx 46 8 for for IN cord-334490-42gykxdx 46 9 treatment treatment NN cord-334490-42gykxdx 46 10 of of IN cord-334490-42gykxdx 46 11 COVID-19 COVID-19 NNP cord-334490-42gykxdx 46 12 are be VBP cord-334490-42gykxdx 46 13 known know VBN cord-334490-42gykxdx 46 14 to to TO cord-334490-42gykxdx 46 15 potentially potentially RB cord-334490-42gykxdx 46 16 cause cause VB cord-334490-42gykxdx 46 17 myocardial myocardial JJ cord-334490-42gykxdx 46 18 damage damage NN cord-334490-42gykxdx 46 19 but but CC cord-334490-42gykxdx 46 20 limited limited JJ cord-334490-42gykxdx 46 21 data datum NNS cord-334490-42gykxdx 46 22 on on IN cord-334490-42gykxdx 46 23 the the DT cord-334490-42gykxdx 46 24 clinical clinical JJ cord-334490-42gykxdx 46 25 significance significance NN cord-334490-42gykxdx 46 26 are be VBP cord-334490-42gykxdx 46 27 available available JJ cord-334490-42gykxdx 46 28 at at IN cord-334490-42gykxdx 46 29 this this DT cord-334490-42gykxdx 46 30 time time NN cord-334490-42gykxdx 46 31 [ [ -LRB- cord-334490-42gykxdx 46 32 21 21 CD cord-334490-42gykxdx 46 33 ] ] -RRB- cord-334490-42gykxdx 46 34 . . . cord-334490-42gykxdx 47 1 Updated update VBN cord-334490-42gykxdx 47 2 information information NN cord-334490-42gykxdx 47 3 may may MD cord-334490-42gykxdx 47 4 be be VB cord-334490-42gykxdx 47 5 found find VBN cord-334490-42gykxdx 47 6 under under IN cord-334490-42gykxdx 47 7 : : : cord-334490-42gykxdx 47 8 https:// https:// NNP cord-334490-42gykxdx 47 9 www.escardio.org/Education/COVID-19-and-Cardiol www.escardio.org/Education/COVID-19-and-Cardiol NNP cord-334490-42gykxdx 47 10 ogy ogy NNP cord-334490-42gykxdx 47 11 . . . cord-334490-42gykxdx 48 1 ( ( -LRB- cord-334490-42gykxdx 48 2 3 3 LS cord-334490-42gykxdx 48 3 ) ) -RRB- cord-334490-42gykxdx 48 4 Should Should MD cord-334490-42gykxdx 48 5 I -PRON- PRP cord-334490-42gykxdx 48 6 use use VB cord-334490-42gykxdx 48 7 anticoagulation anticoagulation NN cord-334490-42gykxdx 48 8 in in IN cord-334490-42gykxdx 48 9 patients patient NNS cord-334490-42gykxdx 48 10 with with IN cord-334490-42gykxdx 48 11 COVID-19 COVID-19 NNP cord-334490-42gykxdx 48 12 ? ? . cord-334490-42gykxdx 49 1 Current current JJ cord-334490-42gykxdx 49 2 literature literature NN cord-334490-42gykxdx 49 3 suggests suggest VBZ cord-334490-42gykxdx 49 4 that that IN cord-334490-42gykxdx 49 5 patients patient NNS cord-334490-42gykxdx 49 6 with with IN cord-334490-42gykxdx 49 7 COVID-19 COVID-19 NNP cord-334490-42gykxdx 49 8 are be VBP cord-334490-42gykxdx 49 9 at at IN cord-334490-42gykxdx 49 10 increased increase VBN cord-334490-42gykxdx 49 11 risk risk NN cord-334490-42gykxdx 49 12 for for IN cord-334490-42gykxdx 49 13 venous venous JJ cord-334490-42gykxdx 49 14 thromboembolism thromboembolism NN cord-334490-42gykxdx 49 15 ( ( -LRB- cord-334490-42gykxdx 49 16 VTE VTE NNP cord-334490-42gykxdx 49 17 ) ) -RRB- cord-334490-42gykxdx 49 18 . . . cord-334490-42gykxdx 50 1 In in IN cord-334490-42gykxdx 50 2 critically critically RB cord-334490-42gykxdx 50 3 ill ill JJ cord-334490-42gykxdx 50 4 patients patient NNS cord-334490-42gykxdx 50 5 , , , cord-334490-42gykxdx 50 6 VTE VTE NNP cord-334490-42gykxdx 50 7 is be VBZ cord-334490-42gykxdx 50 8 frequent frequent JJ cord-334490-42gykxdx 50 9 but but CC cord-334490-42gykxdx 50 10 seems seem VBZ cord-334490-42gykxdx 50 11 to to TO cord-334490-42gykxdx 50 12 occur occur VB cord-334490-42gykxdx 50 13 much much RB cord-334490-42gykxdx 50 14 more more RBR cord-334490-42gykxdx 50 15 frequently frequently RB cord-334490-42gykxdx 50 16 in in IN cord-334490-42gykxdx 50 17 patients patient NNS cord-334490-42gykxdx 50 18 with with IN cord-334490-42gykxdx 50 19 COVID-19 COVID-19 NNP cord-334490-42gykxdx 50 20 , , , cord-334490-42gykxdx 50 21 with with IN cord-334490-42gykxdx 50 22 reported report VBN cord-334490-42gykxdx 50 23 incidence incidence NN cord-334490-42gykxdx 50 24 rates rate NNS cord-334490-42gykxdx 50 25 of of IN cord-334490-42gykxdx 50 26 up up IN cord-334490-42gykxdx 50 27 to to TO cord-334490-42gykxdx 50 28 one one CD cord-334490-42gykxdx 50 29 third third NN cord-334490-42gykxdx 50 30 in in IN cord-334490-42gykxdx 50 31 ICU ICU NNP cord-334490-42gykxdx 50 32 patients patient NNS cord-334490-42gykxdx 50 33 [ [ -LRB- cord-334490-42gykxdx 50 34 22 22 CD cord-334490-42gykxdx 50 35 ] ] -RRB- cord-334490-42gykxdx 50 36 . . . cord-334490-42gykxdx 51 1 The the DT cord-334490-42gykxdx 51 2 US US NNP cord-334490-42gykxdx 51 3 National National NNP cord-334490-42gykxdx 51 4 Institutes Institutes NNPS cord-334490-42gykxdx 51 5 of of IN cord-334490-42gykxdx 51 6 Health Health NNP cord-334490-42gykxdx 51 7 ( ( -LRB- cord-334490-42gykxdx 51 8 NIH NIH NNP cord-334490-42gykxdx 51 9 ) ) -RRB- cord-334490-42gykxdx 51 10 provide provide VBP cord-334490-42gykxdx 51 11 regularly regularly RB cord-334490-42gykxdx 51 12 updated update VBN cord-334490-42gykxdx 51 13 recommendations recommendation NNS cord-334490-42gykxdx 51 14 on on IN cord-334490-42gykxdx 51 15 anticoagulation anticoagulation NN cord-334490-42gykxdx 51 16 strategies strategy NNS cord-334490-42gykxdx 51 17 in in IN cord-334490-42gykxdx 51 18 patients patient NNS cord-334490-42gykxdx 51 19 with with IN cord-334490-42gykxdx 51 20 COVID-19 COVID-19 NNP cord-334490-42gykxdx 51 21 [ [ -LRB- cord-334490-42gykxdx 51 22 21 21 CD cord-334490-42gykxdx 51 23 ] ] -RRB- cord-334490-42gykxdx 51 24 . . . cord-334490-42gykxdx 52 1 In in IN cord-334490-42gykxdx 52 2 nonhospitalized nonhospitalized JJ cord-334490-42gykxdx 52 3 patients patient NNS cord-334490-42gykxdx 52 4 there there EX cord-334490-42gykxdx 52 5 are be VBP cord-334490-42gykxdx 52 6 no no DT cord-334490-42gykxdx 52 7 data data NN cord-334490-42gykxdx 52 8 to to TO cord-334490-42gykxdx 52 9 support support VB cord-334490-42gykxdx 52 10 any any DT cord-334490-42gykxdx 52 11 use use NN cord-334490-42gykxdx 52 12 of of IN cord-334490-42gykxdx 52 13 anticoagulation anticoagulation NN cord-334490-42gykxdx 52 14 . . . cord-334490-42gykxdx 53 1 Patients patient NNS cord-334490-42gykxdx 53 2 receiving receive VBG cord-334490-42gykxdx 53 3 antiplatelet antiplatelet NN cord-334490-42gykxdx 53 4 or or CC cord-334490-42gykxdx 53 5 anticoagulant anticoagulant JJ cord-334490-42gykxdx 53 6 treatment treatment NN cord-334490-42gykxdx 53 7 for for IN cord-334490-42gykxdx 53 8 underlying underlying JJ cord-334490-42gykxdx 53 9 conditions condition NNS cord-334490-42gykxdx 53 10 should should MD cord-334490-42gykxdx 53 11 continue continue VB cord-334490-42gykxdx 53 12 their -PRON- PRP$ cord-334490-42gykxdx 53 13 medications medication NNS cord-334490-42gykxdx 53 14 irrespective irrespective RB cord-334490-42gykxdx 53 15 of of IN cord-334490-42gykxdx 53 16 a a DT cord-334490-42gykxdx 53 17 COVID-19 covid-19 JJ cord-334490-42gykxdx 53 18 diagnosis diagnosis NN cord-334490-42gykxdx 53 19 [ [ -LRB- cord-334490-42gykxdx 53 20 21 21 CD cord-334490-42gykxdx 53 21 ] ] -RRB- cord-334490-42gykxdx 53 22 . . . cord-334490-42gykxdx 54 1 In in IN cord-334490-42gykxdx 54 2 patients patient NNS cord-334490-42gykxdx 54 3 hospitalized hospitalize VBN cord-334490-42gykxdx 54 4 with with IN cord-334490-42gykxdx 54 5 COVID-19 COVID-19 NNP cord-334490-42gykxdx 54 6 , , , cord-334490-42gykxdx 54 7 both both CC cord-334490-42gykxdx 54 8 NIH NIH NNP cord-334490-42gykxdx 54 9 and and CC cord-334490-42gykxdx 54 10 the the DT cord-334490-42gykxdx 54 11 anticoagulation anticoagulation NN cord-334490-42gykxdx 54 12 forum forum NN cord-334490-42gykxdx 54 13 recommend recommend VBP cord-334490-42gykxdx 54 14 pharmacologic pharmacologic JJ cord-334490-42gykxdx 54 15 VTE VTE NNP cord-334490-42gykxdx 54 16 prophylaxis prophylaxis NN cord-334490-42gykxdx 54 17 [ [ -LRB- cord-334490-42gykxdx 54 18 21 21 CD cord-334490-42gykxdx 54 19 , , , cord-334490-42gykxdx 54 20 23 23 CD cord-334490-42gykxdx 54 21 ] ] -RRB- cord-334490-42gykxdx 54 22 ; ; : cord-334490-42gykxdx 54 23 however however RB cord-334490-42gykxdx 54 24 , , , cord-334490-42gykxdx 54 25 irrespective irrespective RB cord-334490-42gykxdx 54 26 of of IN cord-334490-42gykxdx 54 27 laboratory laboratory NN cord-334490-42gykxdx 54 28 findings finding NNS cord-334490-42gykxdx 54 29 , , , cord-334490-42gykxdx 54 30 there there EX cord-334490-42gykxdx 54 31 are be VBP cord-334490-42gykxdx 54 32 currently currently RB cord-334490-42gykxdx 54 33 insufficient insufficient JJ cord-334490-42gykxdx 54 34 data datum NNS cord-334490-42gykxdx 54 35 to to TO cord-334490-42gykxdx 54 36 support support VB cord-334490-42gykxdx 54 37 routine routine JJ cord-334490-42gykxdx 54 38 screening screening NN cord-334490-42gykxdx 54 39 for for IN cord-334490-42gykxdx 54 40 VTE VTE NNP cord-334490-42gykxdx 54 41 in in IN cord-334490-42gykxdx 54 42 patients patient NNS cord-334490-42gykxdx 54 43 without without IN cord-334490-42gykxdx 54 44 clinical clinical JJ cord-334490-42gykxdx 54 45 signs sign NNS cord-334490-42gykxdx 54 46 suggestive suggestive JJ cord-334490-42gykxdx 54 47 of of IN cord-334490-42gykxdx 54 48 VTE VTE NNP cord-334490-42gykxdx 54 49 . . . cord-334490-42gykxdx 55 1 Patients patient NNS cord-334490-42gykxdx 55 2 with with IN cord-334490-42gykxdx 55 3 confirmed confirm VBN cord-334490-42gykxdx 55 4 thromboembolic thromboembolic JJ cord-334490-42gykxdx 55 5 events event NNS cord-334490-42gykxdx 55 6 who who WP cord-334490-42gykxdx 55 7 have have VBP cord-334490-42gykxdx 55 8 been be VBN cord-334490-42gykxdx 55 9 diagnosed diagnose VBN cord-334490-42gykxdx 55 10 with with IN cord-334490-42gykxdx 55 11 COVID-19 COVID-19 NNP cord-334490-42gykxdx 55 12 should should MD cord-334490-42gykxdx 55 13 receive receive VB cord-334490-42gykxdx 55 14 standard standard NN cord-334490-42gykxdx 55 15 of of IN cord-334490-42gykxdx 55 16 care care NN cord-334490-42gykxdx 55 17 anticoagulation anticoagulation NN cord-334490-42gykxdx 55 18 treatment treatment NN cord-334490-42gykxdx 55 19 [ [ -LRB- cord-334490-42gykxdx 55 20 21 21 CD cord-334490-42gykxdx 55 21 ] ] -RRB- cord-334490-42gykxdx 55 22 . . . cord-334490-42gykxdx 56 1 Updated update VBN cord-334490-42gykxdx 56 2 information information NN cord-334490-42gykxdx 56 3 may may MD cord-334490-42gykxdx 56 4 be be VB cord-334490-42gykxdx 56 5 found find VBN cord-334490-42gykxdx 56 6 under under IN cord-334490-42gykxdx 56 7 : : : cord-334490-42gykxdx 57 1 https:// https:// NNP cord-334490-42gykxdx 57 2 www.covid19treatmentguidelines.nih.gov/antithromb www.covid19treatmentguidelines.nih.gov/antithromb CD cord-334490-42gykxdx 57 3 otic otic NNP cord-334490-42gykxdx 57 4 - - HYPH cord-334490-42gykxdx 57 5 therapy/. therapy/. NNP cord-334490-42gykxdx 57 6 ( ( -LRB- cord-334490-42gykxdx 57 7 4 4 CD cord-334490-42gykxdx 57 8 ) ) -RRB- cord-334490-42gykxdx 58 1 How how WRB cord-334490-42gykxdx 58 2 long long RB cord-334490-42gykxdx 58 3 can can MD cord-334490-42gykxdx 58 4 invasive invasive JJ cord-334490-42gykxdx 58 5 procedures procedure NNS cord-334490-42gykxdx 58 6 for for IN cord-334490-42gykxdx 58 7 cardiac cardiac JJ cord-334490-42gykxdx 58 8 conditions condition NNS cord-334490-42gykxdx 58 9 be be VB cord-334490-42gykxdx 58 10 postponed postpone VBN cord-334490-42gykxdx 58 11 ? ? . cord-334490-42gykxdx 59 1 As as IN cord-334490-42gykxdx 59 2 healthcare healthcare NN cord-334490-42gykxdx 59 3 systems system NNS cord-334490-42gykxdx 59 4 around around IN cord-334490-42gykxdx 59 5 the the DT cord-334490-42gykxdx 59 6 globe globe NN cord-334490-42gykxdx 59 7 experience experience VB cord-334490-42gykxdx 59 8 unprecedented unprecedented JJ cord-334490-42gykxdx 59 9 challenges challenge NNS cord-334490-42gykxdx 59 10 , , , cord-334490-42gykxdx 59 11 clinical clinical JJ cord-334490-42gykxdx 59 12 management management NN cord-334490-42gykxdx 59 13 of of IN cord-334490-42gykxdx 59 14 all all DT cord-334490-42gykxdx 59 15 chronic chronic JJ cord-334490-42gykxdx 59 16 cardiac cardiac JJ cord-334490-42gykxdx 59 17 conditions condition NNS cord-334490-42gykxdx 59 18 has have VBZ cord-334490-42gykxdx 59 19 changed change VBN cord-334490-42gykxdx 59 20 dramatically dramatically RB cord-334490-42gykxdx 59 21 . . . cord-334490-42gykxdx 60 1 The the DT cord-334490-42gykxdx 60 2 European European NNP cord-334490-42gykxdx 60 3 Society Society NNP cord-334490-42gykxdx 60 4 of of IN cord-334490-42gykxdx 60 5 Cardiology Cardiology NNP cord-334490-42gykxdx 60 6 ( ( -LRB- cord-334490-42gykxdx 60 7 ESC ESC NNP cord-334490-42gykxdx 60 8 ) ) -RRB- cord-334490-42gykxdx 60 9 issued issue VBD cord-334490-42gykxdx 60 10 a a DT cord-334490-42gykxdx 60 11 guidance guidance NN cord-334490-42gykxdx 60 12 document document NN cord-334490-42gykxdx 60 13 on on IN cord-334490-42gykxdx 60 14 how how WRB cord-334490-42gykxdx 60 15 to to TO cord-334490-42gykxdx 60 16 prioritize prioritize VB cord-334490-42gykxdx 60 17 management management NN cord-334490-42gykxdx 60 18 in in IN cord-334490-42gykxdx 60 19 patients patient NNS cord-334490-42gykxdx 60 20 with with IN cord-334490-42gykxdx 60 21 cardiac cardiac JJ cord-334490-42gykxdx 60 22 conditions condition NNS cord-334490-42gykxdx 60 23 [ [ -LRB- cord-334490-42gykxdx 60 24 24 24 CD cord-334490-42gykxdx 60 25 ] ] -RRB- cord-334490-42gykxdx 60 26 . . . cord-334490-42gykxdx 61 1 Patients patient NNS cord-334490-42gykxdx 61 2 with with IN cord-334490-42gykxdx 61 3 ACS ACS NNP cord-334490-42gykxdx 61 4 , , , cord-334490-42gykxdx 61 5 left leave VBD cord-334490-42gykxdx 61 6 main main JJ cord-334490-42gykxdx 61 7 PCI pci NN cord-334490-42gykxdx 61 8 , , , cord-334490-42gykxdx 61 9 battery battery NN cord-334490-42gykxdx 61 10 replacement replacement NN cord-334490-42gykxdx 61 11 in in IN cord-334490-42gykxdx 61 12 case case NN cord-334490-42gykxdx 61 13 of of IN cord-334490-42gykxdx 61 14 battery battery NN cord-334490-42gykxdx 61 15 end end NN cord-334490-42gykxdx 61 16 of of IN cord-334490-42gykxdx 61 17 life life NN cord-334490-42gykxdx 61 18 and and CC cord-334490-42gykxdx 61 19 pacing pace VBG cord-334490-42gykxdx 61 20 dependency dependency NN cord-334490-42gykxdx 61 21 , , , cord-334490-42gykxdx 61 22 and and CC cord-334490-42gykxdx 61 23 valvular valvular JJ cord-334490-42gykxdx 61 24 heart heart NN cord-334490-42gykxdx 61 25 disease disease NN cord-334490-42gykxdx 61 26 , , , cord-334490-42gykxdx 61 27 who who WP cord-334490-42gykxdx 61 28 are be VBP cord-334490-42gykxdx 61 29 hemodynamically hemodynamically RB cord-334490-42gykxdx 61 30 unstable unstable JJ cord-334490-42gykxdx 61 31 should should MD cord-334490-42gykxdx 61 32 be be VB cord-334490-42gykxdx 61 33 considered consider VBN cord-334490-42gykxdx 61 34 emergency emergency NN cord-334490-42gykxdx 61 35 and and CC cord-334490-42gykxdx 61 36 urgent urgent JJ cord-334490-42gykxdx 61 37 priority priority NN cord-334490-42gykxdx 61 38 and and CC cord-334490-42gykxdx 61 39 invasive invasive JJ cord-334490-42gykxdx 61 40 procedures procedure NNS cord-334490-42gykxdx 61 41 should should MD cord-334490-42gykxdx 61 42 not not RB cord-334490-42gykxdx 61 43 be be VB cord-334490-42gykxdx 61 44 postponed postpone VBN cord-334490-42gykxdx 61 45 . . . cord-334490-42gykxdx 62 1 Symptomatic symptomatic JJ cord-334490-42gykxdx 62 2 patients patient NNS cord-334490-42gykxdx 62 3 with with IN cord-334490-42gykxdx 62 4 severe severe JJ cord-334490-42gykxdx 62 5 aortic aortic JJ cord-334490-42gykxdx 62 6 stenosis stenosis NN cord-334490-42gykxdx 62 7 should should MD cord-334490-42gykxdx 62 8 undergo undergo VB cord-334490-42gykxdx 62 9 valve valve NN cord-334490-42gykxdx 62 10 replacement replacement NN cord-334490-42gykxdx 62 11 within within IN cord-334490-42gykxdx 62 12 3 3 CD cord-334490-42gykxdx 62 13 months month NNS cord-334490-42gykxdx 62 14 in in IN cord-334490-42gykxdx 62 15 cases case NNS cord-334490-42gykxdx 62 16 of of IN cord-334490-42gykxdx 62 17 advanced advanced JJ cord-334490-42gykxdx 62 18 disease disease NN cord-334490-42gykxdx 62 19 state state NN cord-334490-42gykxdx 62 20 ( ( -LRB- cord-334490-42gykxdx 62 21 aortic aortic JJ cord-334490-42gykxdx 62 22 valve valve NN cord-334490-42gykxdx 62 23 area area NN cord-334490-42gykxdx 62 24 < < XX cord-334490-42gykxdx 62 25 0.6 0.6 CD cord-334490-42gykxdx 62 26 cm cm NN cord-334490-42gykxdx 62 27 2 2 CD cord-334490-42gykxdx 62 28 , , , cord-334490-42gykxdx 62 29 mean mean VB cord-334490-42gykxdx 62 30 transvalvular transvalvular NN cord-334490-42gykxdx 62 31 gradient gradient NN cord-334490-42gykxdx 63 1 > > XX cord-334490-42gykxdx 64 1 60 60 CD cord-334490-42gykxdx 64 2 mm mm CD cord-334490-42gykxdx 64 3 Hg Hg NNP cord-334490-42gykxdx 64 4 ) ) -RRB- cord-334490-42gykxdx 64 5 . . . cord-334490-42gykxdx 65 1 All all DT cord-334490-42gykxdx 65 2 cases case NNS cord-334490-42gykxdx 65 3 should should MD cord-334490-42gykxdx 65 4 be be VB cord-334490-42gykxdx 65 5 discussed discuss VBN cord-334490-42gykxdx 65 6 by by IN cord-334490-42gykxdx 65 7 the the DT cord-334490-42gykxdx 65 8 interdisciplinary interdisciplinary JJ cord-334490-42gykxdx 65 9 heart heart NN cord-334490-42gykxdx 65 10 team team NN cord-334490-42gykxdx 65 11 and and CC cord-334490-42gykxdx 65 12 indications indication NNS cord-334490-42gykxdx 65 13 for for IN cord-334490-42gykxdx 65 14 transcatheter transcatheter JJ cord-334490-42gykxdx 65 15 aortic aortic JJ cord-334490-42gykxdx 65 16 valve valve NN cord-334490-42gykxdx 65 17 implantation implantation NN cord-334490-42gykxdx 65 18 ( ( -LRB- cord-334490-42gykxdx 65 19 TAVI TAVI NNP cord-334490-42gykxdx 65 20 ) ) -RRB- cord-334490-42gykxdx 65 21 extended extend VBD cord-334490-42gykxdx 65 22 to to IN cord-334490-42gykxdx 65 23 intermediate intermediate JJ cord-334490-42gykxdx 65 24 and and CC cord-334490-42gykxdx 65 25 selected select VBN cord-334490-42gykxdx 65 26 low low JJ cord-334490-42gykxdx 65 27 - - HYPH cord-334490-42gykxdx 65 28 risk risk NN cord-334490-42gykxdx 65 29 patients patient NNS cord-334490-42gykxdx 65 30 . . . cord-334490-42gykxdx 66 1 Increased increase VBN cord-334490-42gykxdx 66 2 use use NN cord-334490-42gykxdx 66 3 of of IN cord-334490-42gykxdx 66 4 transfemoral transfemoral JJ cord-334490-42gykxdx 66 5 TAVI TAVI NNP cord-334490-42gykxdx 66 6 ( ( -LRB- cord-334490-42gykxdx 66 7 when when WRB cord-334490-42gykxdx 66 8 feasible feasible JJ cord-334490-42gykxdx 66 9 ) ) -RRB- cord-334490-42gykxdx 66 10 may may MD cord-334490-42gykxdx 66 11 allow allow VB cord-334490-42gykxdx 66 12 optimal optimal JJ cord-334490-42gykxdx 66 13 utilization utilization NN cord-334490-42gykxdx 66 14 of of IN cord-334490-42gykxdx 66 15 resources resource NNS cord-334490-42gykxdx 66 16 by by IN cord-334490-42gykxdx 66 17 avoiding avoid VBG cord-334490-42gykxdx 66 18 general general JJ cord-334490-42gykxdx 66 19 anesthesia anesthesia NNP cord-334490-42gykxdx 67 1 COVID-19 covid-19 VB cord-334490-42gykxdx 67 2 : : : cord-334490-42gykxdx 67 3 frequently frequently RB cord-334490-42gykxdx 67 4 asked ask VBN cord-334490-42gykxdx 67 5 questions question NNS cord-334490-42gykxdx 67 6 to to IN cord-334490-42gykxdx 67 7 the the DT cord-334490-42gykxdx 67 8 cardiologist cardiologist NN cord-334490-42gykxdx 67 9 K K NNP cord-334490-42gykxdx 67 10 main main JJ cord-334490-42gykxdx 67 11 topic topic NN cord-334490-42gykxdx 67 12 and and CC cord-334490-42gykxdx 67 13 intubation intubation NN cord-334490-42gykxdx 67 14 , , , cord-334490-42gykxdx 67 15 shortening shortening NN cord-334490-42gykxdx 67 16 ( ( -LRB- cord-334490-42gykxdx 67 17 or or CC cord-334490-42gykxdx 67 18 preventing prevent VBG cord-334490-42gykxdx 67 19 ) ) -RRB- cord-334490-42gykxdx 68 1 ICU ICU NNP cord-334490-42gykxdx 68 2 stay stay VBP cord-334490-42gykxdx 68 3 and and CC cord-334490-42gykxdx 68 4 accelerating accelerate VBG cord-334490-42gykxdx 68 5 hospital hospital NN cord-334490-42gykxdx 68 6 discharge discharge NN cord-334490-42gykxdx 68 7 and and CC cord-334490-42gykxdx 68 8 recovery recovery NN cord-334490-42gykxdx 68 9 . . . cord-334490-42gykxdx 69 1 Updated update VBN cord-334490-42gykxdx 69 2 information information NN cord-334490-42gykxdx 69 3 may may MD cord-334490-42gykxdx 69 4 be be VB cord-334490-42gykxdx 69 5 found find VBN cord-334490-42gykxdx 69 6 under under IN cord-334490-42gykxdx 69 7 : : : cord-334490-42gykxdx 69 8 https:// https:// NNP cord-334490-42gykxdx 69 9 www.escardio.org/Education/COVID-19-and-Cardiol www.escardio.org/Education/COVID-19-and-Cardiol NNP cord-334490-42gykxdx 69 10 ogy ogy NNP cord-334490-42gykxdx 69 11 / / SYM cord-334490-42gykxdx 69 12 ESC ESC NNP cord-334490-42gykxdx 69 13 - - HYPH cord-334490-42gykxdx 69 14 COVID-19-Guidance COVID-19-Guidance NNP cord-334490-42gykxdx 69 15 . . . cord-334490-42gykxdx 70 1 A a DT cord-334490-42gykxdx 70 2 Novel Novel NNP cord-334490-42gykxdx 70 3 Coronavirus Coronavirus NNP cord-334490-42gykxdx 70 4 from from IN cord-334490-42gykxdx 70 5 Patients patient NNS cord-334490-42gykxdx 70 6 with with IN cord-334490-42gykxdx 70 7 Pneumonia Pneumonia NNP cord-334490-42gykxdx 70 8 in in IN cord-334490-42gykxdx 70 9 China China NNP cord-334490-42gykxdx 70 10 Clinical Clinical NNP cord-334490-42gykxdx 70 11 Characteristics Characteristics NNPS cord-334490-42gykxdx 70 12 of of IN cord-334490-42gykxdx 70 13 Coronavirus Coronavirus NNP cord-334490-42gykxdx 70 14 Disease Disease NNP cord-334490-42gykxdx 70 15 2019 2019 CD cord-334490-42gykxdx 70 16 in in IN cord-334490-42gykxdx 70 17 China China NNP cord-334490-42gykxdx 71 1 A a DT cord-334490-42gykxdx 71 2 novel novel JJ cord-334490-42gykxdx 71 3 Coronavirus Coronavirus NNP cord-334490-42gykxdx 71 4 emerging emerge VBG cord-334490-42gykxdx 71 5 in in IN cord-334490-42gykxdx 71 6 China China NNP cord-334490-42gykxdx 71 7 - - HYPH cord-334490-42gykxdx 71 8 key key JJ cord-334490-42gykxdx 71 9 questions question NNS cord-334490-42gykxdx 71 10 for for IN cord-334490-42gykxdx 71 11 impact impact NN cord-334490-42gykxdx 71 12 assessment assessment NN cord-334490-42gykxdx 71 13 Epidemiological epidemiological JJ cord-334490-42gykxdx 71 14 and and CC cord-334490-42gykxdx 71 15 clinical clinical JJ cord-334490-42gykxdx 71 16 characteristics characteristic NNS cord-334490-42gykxdx 71 17 of of IN cord-334490-42gykxdx 71 18 99 99 CD cord-334490-42gykxdx 71 19 cases case NNS cord-334490-42gykxdx 71 20 of of IN cord-334490-42gykxdx 71 21 2019 2019 CD cord-334490-42gykxdx 71 22 novel novel JJ cord-334490-42gykxdx 71 23 coronavirus coronavirus NN cord-334490-42gykxdx 71 24 pneumonia pneumonia NN cord-334490-42gykxdx 71 25 in in IN cord-334490-42gykxdx 71 26 Wuhan Wuhan NNP cord-334490-42gykxdx 71 27 , , , cord-334490-42gykxdx 71 28 China China NNP cord-334490-42gykxdx 71 29 : : : cord-334490-42gykxdx 71 30 a a DT cord-334490-42gykxdx 71 31 descriptive descriptive JJ cord-334490-42gykxdx 71 32 study study NN cord-334490-42gykxdx 71 33 Association Association NNP cord-334490-42gykxdx 71 34 of of IN cord-334490-42gykxdx 71 35 Cardiac Cardiac NNP cord-334490-42gykxdx 71 36 Injury Injury NNP cord-334490-42gykxdx 71 37 With with IN cord-334490-42gykxdx 71 38 Mortality mortality NN cord-334490-42gykxdx 71 39 in in IN cord-334490-42gykxdx 71 40 Hospitalized Hospitalized NNP cord-334490-42gykxdx 71 41 Patients Patients NNP cord-334490-42gykxdx 71 42 With with IN cord-334490-42gykxdx 71 43 COVID-19 COVID-19 NNP cord-334490-42gykxdx 71 44 in in IN cord-334490-42gykxdx 71 45 Wuhan Wuhan NNP cord-334490-42gykxdx 71 46 , , , cord-334490-42gykxdx 71 47 China China NNP cord-334490-42gykxdx 71 48 Cardiovascular Cardiovascular NNP cord-334490-42gykxdx 71 49 implications implication NNS cord-334490-42gykxdx 71 50 of of IN cord-334490-42gykxdx 71 51 fatal fatal JJ cord-334490-42gykxdx 71 52 outcomes outcome NNS cord-334490-42gykxdx 71 53 of of IN cord-334490-42gykxdx 71 54 patients patient NNS cord-334490-42gykxdx 71 55 with with IN cord-334490-42gykxdx 71 56 Coronavirus Coronavirus NNP cord-334490-42gykxdx 71 57 disease disease NN cord-334490-42gykxdx 71 58 2019 2019 CD cord-334490-42gykxdx 72 1 ( ( -LRB- cord-334490-42gykxdx 72 2 COVID-19 covid-19 VB cord-334490-42gykxdx 72 3 ) ) -RRB- cord-334490-42gykxdx 72 4 Myocardial myocardial JJ cord-334490-42gykxdx 72 5 injury injury NN cord-334490-42gykxdx 72 6 in in IN cord-334490-42gykxdx 72 7 critically critically RB cord-334490-42gykxdx 72 8 ill ill JJ cord-334490-42gykxdx 72 9 patients patient NNS cord-334490-42gykxdx 72 10 . . . cord-334490-42gykxdx 73 1 A a DT cord-334490-42gykxdx 73 2 frequently frequently RB cord-334490-42gykxdx 73 3 unrecognized unrecognized JJ cord-334490-42gykxdx 73 4 complication complication NN cord-334490-42gykxdx 73 5 Coronavirus Coronavirus NNP cord-334490-42gykxdx 73 6 fulminant fulminant JJ cord-334490-42gykxdx 73 7 myocarditis myocarditis NN cord-334490-42gykxdx 73 8 saved save VBN cord-334490-42gykxdx 73 9 with with IN cord-334490-42gykxdx 73 10 glucocorticoid glucocorticoid NN cord-334490-42gykxdx 73 11 and and CC cord-334490-42gykxdx 73 12 human human JJ cord-334490-42gykxdx 73 13 immunoglobulin immunoglobulin NN cord-334490-42gykxdx 73 14 Receptor Receptor NNP cord-334490-42gykxdx 73 15 recognition recognition NN cord-334490-42gykxdx 73 16 by by IN cord-334490-42gykxdx 73 17 the the DT cord-334490-42gykxdx 73 18 novel novel JJ cord-334490-42gykxdx 73 19 Coronavirus Coronavirus NNP cord-334490-42gykxdx 73 20 from from IN cord-334490-42gykxdx 73 21 Wuhan Wuhan NNP cord-334490-42gykxdx 73 22 : : : cord-334490-42gykxdx 73 23 an an DT cord-334490-42gykxdx 73 24 analysis analysis NN cord-334490-42gykxdx 73 25 based base VBN cord-334490-42gykxdx 73 26 on on IN cord-334490-42gykxdx 73 27 decade decade NN cord-334490-42gykxdx 73 28 - - HYPH cord-334490-42gykxdx 73 29 long long JJ cord-334490-42gykxdx 73 30 structural structural JJ cord-334490-42gykxdx 73 31 studies study NNS cord-334490-42gykxdx 73 32 of of IN cord-334490-42gykxdx 73 33 SARS SARS NNP cord-334490-42gykxdx 73 34 Coronavirus Coronavirus NNP cord-334490-42gykxdx 73 35 Vital vital JJ cord-334490-42gykxdx 73 36 surveillances surveillance NNS cord-334490-42gykxdx 73 37 : : : cord-334490-42gykxdx 73 38 the the DT cord-334490-42gykxdx 73 39 epidemiological epidemiological JJ cord-334490-42gykxdx 73 40 characteristics characteristic NNS cord-334490-42gykxdx 73 41 of of IN cord-334490-42gykxdx 73 42 an an DT cord-334490-42gykxdx 73 43 outbreak outbreak NN cord-334490-42gykxdx 73 44 of of IN cord-334490-42gykxdx 73 45 2019 2019 CD cord-334490-42gykxdx 73 46 novel novel JJ cord-334490-42gykxdx 73 47 coronavirus coronavirus NN cord-334490-42gykxdx 73 48 diseases disease NNS cord-334490-42gykxdx 73 49 ( ( -LRB- cord-334490-42gykxdx 73 50 COVID-19)-China COVID-19)-China NNP cord-334490-42gykxdx 73 51 , , , cord-334490-42gykxdx 73 52 2020 2020 CD cord-334490-42gykxdx 73 53 . . . cord-334490-42gykxdx 74 1 China China NNP cord-334490-42gykxdx 74 2 CDC CDC NNP cord-334490-42gykxdx 74 3 Weekly Weekly NNP cord-334490-42gykxdx 74 4 Angiotensin Angiotensin NNP cord-334490-42gykxdx 74 5 - - HYPH cord-334490-42gykxdx 74 6 converting convert VBG cord-334490-42gykxdx 74 7 enzyme enzyme NN cord-334490-42gykxdx 74 8 2 2 CD cord-334490-42gykxdx 74 9 ( ( -LRB- cord-334490-42gykxdx 74 10 ACE2 ACE2 NNP cord-334490-42gykxdx 74 11 ) ) -RRB- cord-334490-42gykxdx 74 12 mediates mediate VBZ cord-334490-42gykxdx 74 13 influenza influenza NN cord-334490-42gykxdx 74 14 H7N9 H7N9 NNP cord-334490-42gykxdx 74 15 virus virus NN cord-334490-42gykxdx 74 16 - - HYPH cord-334490-42gykxdx 74 17 induced induce VBN cord-334490-42gykxdx 74 18 acute acute JJ cord-334490-42gykxdx 74 19 lung lung NN cord-334490-42gykxdx 74 20 injury injury NN cord-334490-42gykxdx 74 21 Risks risk NNS cord-334490-42gykxdx 74 22 and and CC cord-334490-42gykxdx 74 23 impact impact NN cord-334490-42gykxdx 74 24 of of IN cord-334490-42gykxdx 74 25 Angiotensin angiotensin NN cord-334490-42gykxdx 74 26 - - HYPH cord-334490-42gykxdx 74 27 converting convert VBG cord-334490-42gykxdx 74 28 enzyme enzyme NN cord-334490-42gykxdx 74 29 inhibitors inhibitor NNS cord-334490-42gykxdx 74 30 or or CC cord-334490-42gykxdx 74 31 Angiotensinreceptor Angiotensinreceptor NNP cord-334490-42gykxdx 74 32 blockers blocker NNS cord-334490-42gykxdx 74 33 on on IN cord-334490-42gykxdx 74 34 SARS SARS NNP cord-334490-42gykxdx 74 35 - - HYPH cord-334490-42gykxdx 74 36 coV-2 coV-2 NNP cord-334490-42gykxdx 74 37 infection infection NN cord-334490-42gykxdx 74 38 in in IN cord-334490-42gykxdx 74 39 adults adults NNPS cord-334490-42gykxdx 74 40 Association Association NNP cord-334490-42gykxdx 74 41 of of IN cord-334490-42gykxdx 74 42 Renin Renin NNP cord-334490-42gykxdx 74 43 - - HYPH cord-334490-42gykxdx 74 44 Angiotensin Angiotensin NNP cord-334490-42gykxdx 74 45 system system NN cord-334490-42gykxdx 74 46 inhibitors inhibitor NNS cord-334490-42gykxdx 74 47 with with IN cord-334490-42gykxdx 74 48 severity severity NN cord-334490-42gykxdx 74 49 or or CC cord-334490-42gykxdx 74 50 risk risk NN cord-334490-42gykxdx 74 51 of of IN cord-334490-42gykxdx 74 52 death death NN cord-334490-42gykxdx 74 53 in in IN cord-334490-42gykxdx 74 54 patients patient NNS cord-334490-42gykxdx 74 55 with with IN cord-334490-42gykxdx 74 56 hypertension hypertension NN cord-334490-42gykxdx 74 57 hospitalized hospitalize VBN cord-334490-42gykxdx 74 58 for for IN cord-334490-42gykxdx 74 59 Coronavirus Coronavirus NNP cord-334490-42gykxdx 74 60 disease disease NN cord-334490-42gykxdx 74 61 2019 2019 CD cord-334490-42gykxdx 74 62 ( ( -LRB- cord-334490-42gykxdx 74 63 COVID-19 COVID-19 NNP cord-334490-42gykxdx 74 64 ) ) -RRB- cord-334490-42gykxdx 74 65 infection infection NN cord-334490-42gykxdx 74 66 in in IN cord-334490-42gykxdx 74 67 Wuhan Wuhan NNP cord-334490-42gykxdx 74 68 , , , cord-334490-42gykxdx 74 69 China China NNP cord-334490-42gykxdx 74 70 Association Association NNP cord-334490-42gykxdx 74 71 of of IN cord-334490-42gykxdx 74 72 inpatient inpatient JJ cord-334490-42gykxdx 74 73 use use NN cord-334490-42gykxdx 74 74 of of IN cord-334490-42gykxdx 74 75 Angiotensin Angiotensin NNP cord-334490-42gykxdx 74 76 converting convert VBG cord-334490-42gykxdx 74 77 enzyme enzyme NN cord-334490-42gykxdx 74 78 inhibitors inhibitor NNS cord-334490-42gykxdx 74 79 and and CC cord-334490-42gykxdx 74 80 Angiotensin Angiotensin NNP cord-334490-42gykxdx 74 81 II II NNP cord-334490-42gykxdx 74 82 receptor receptor NN cord-334490-42gykxdx 74 83 blockers blocker NNS cord-334490-42gykxdx 74 84 with with IN cord-334490-42gykxdx 74 85 mortality mortality NN cord-334490-42gykxdx 74 86 among among IN cord-334490-42gykxdx 74 87 patients patient NNS cord-334490-42gykxdx 74 88 with with IN cord-334490-42gykxdx 74 89 hypertension hypertension NN cord-334490-42gykxdx 74 90 hospitalized hospitalize VBN cord-334490-42gykxdx 74 91 with with IN cord-334490-42gykxdx 74 92 COVID-19 COVID-19 NNP cord-334490-42gykxdx 74 93 EMA EMA NNP cord-334490-42gykxdx 74 94 advises advise VBZ cord-334490-42gykxdx 74 95 continued continued JJ cord-334490-42gykxdx 74 96 use use NN cord-334490-42gykxdx 74 97 of of IN cord-334490-42gykxdx 74 98 medicines medicine NNS cord-334490-42gykxdx 74 99 for for IN cord-334490-42gykxdx 74 100 hypertension hypertension NN cord-334490-42gykxdx 74 101 , , , cord-334490-42gykxdx 74 102 heart heart NN cord-334490-42gykxdx 74 103 or or CC cord-334490-42gykxdx 74 104 kidney kidney NN cord-334490-42gykxdx 74 105 disease disease NN cord-334490-42gykxdx 74 106 during during IN cord-334490-42gykxdx 74 107 COVID-19 COVID-19 NNP cord-334490-42gykxdx 74 108 pandemic pandemic NN cord-334490-42gykxdx 75 1 HFSA HFSA NNP cord-334490-42gykxdx 75 2 / / SYM cord-334490-42gykxdx 75 3 ACC ACC NNP cord-334490-42gykxdx 75 4 / / SYM cord-334490-42gykxdx 75 5 AHA AHA NNP cord-334490-42gykxdx 75 6 Statement Statement NNP cord-334490-42gykxdx 76 1 Addresses address NNS cord-334490-42gykxdx 76 2 Concerns concern NNS cord-334490-42gykxdx 76 3 Re re IN cord-334490-42gykxdx 76 4 : : : cord-334490-42gykxdx 76 5 Using use VBG cord-334490-42gykxdx 76 6 RAAS RAAS NNP cord-334490-42gykxdx 76 7 Antagonists Antagonists NNPS cord-334490-42gykxdx 76 8 in in IN cord-334490-42gykxdx 76 9 COVID-19 COVID-19 NNP cord-334490-42gykxdx 76 10 Considerations consideration NNS cord-334490-42gykxdx 76 11 for for IN cord-334490-42gykxdx 76 12 Certain certain JJ cord-334490-42gykxdx 76 13 Concomitant concomitant JJ cord-334490-42gykxdx 76 14 Medications medication NNS cord-334490-42gykxdx 76 15 in in IN cord-334490-42gykxdx 76 16 Patients patient NNS cord-334490-42gykxdx 76 17 with with IN cord-334490-42gykxdx 76 18 COVID-19 COVID-19 NNP cord-334490-42gykxdx 76 19 . . . cord-334490-42gykxdx 77 1 NIH NIH NNP cord-334490-42gykxdx 77 2 COVID-19 COVID-19 NNP cord-334490-42gykxdx 77 3 Treatment Treatment NNP cord-334490-42gykxdx 77 4 Guidelines Guidelines NNPS cord-334490-42gykxdx 77 5 EAPCI EAPCI NNP cord-334490-42gykxdx 77 6 position position NN cord-334490-42gykxdx 77 7 statement statement NN cord-334490-42gykxdx 77 8 on on IN cord-334490-42gykxdx 77 9 invasive invasive JJ cord-334490-42gykxdx 77 10 management management NN cord-334490-42gykxdx 77 11 of of IN cord-334490-42gykxdx 77 12 acute acute JJ cord-334490-42gykxdx 77 13 coronary coronary JJ cord-334490-42gykxdx 77 14 syndromes syndrome NNS cord-334490-42gykxdx 77 15 during during IN cord-334490-42gykxdx 77 16 the the DT cord-334490-42gykxdx 77 17 COVID-19 COVID-19 NNP cord-334490-42gykxdx 77 18 pandemic pandemic NN cord-334490-42gykxdx 77 19 Reduction reduction NN cord-334490-42gykxdx 77 20 in in IN cord-334490-42gykxdx 77 21 STsegment STsegment NNP cord-334490-42gykxdx 77 22 elevation elevation NN cord-334490-42gykxdx 77 23 cardiac cardiac JJ cord-334490-42gykxdx 77 24 catheterization catheterization NN cord-334490-42gykxdx 77 25 laboratory laboratory NN cord-334490-42gykxdx 77 26 activations activation NNS cord-334490-42gykxdx 77 27 in in IN cord-334490-42gykxdx 77 28 the the DT cord-334490-42gykxdx 77 29 United United NNP cord-334490-42gykxdx 77 30 States States NNP cord-334490-42gykxdx 77 31 during during IN cord-334490-42gykxdx 77 32 COVID-19 covid-19 CD cord-334490-42gykxdx 77 33 pandemic pandemic NN cord-334490-42gykxdx 77 34 Antithrombotic Antithrombotic NNP cord-334490-42gykxdx 77 35 Therapy Therapy NNP cord-334490-42gykxdx 77 36 in in IN cord-334490-42gykxdx 77 37 Patients Patients NNPS cord-334490-42gykxdx 77 38 with with IN cord-334490-42gykxdx 77 39 COVID-19 COVID-19 NNP cord-334490-42gykxdx 77 40 . . . cord-334490-42gykxdx 78 1 NIH NIH NNP cord-334490-42gykxdx 78 2 COVID-19 COVID-19 NNP cord-334490-42gykxdx 78 3 Treatment Treatment NNP cord-334490-42gykxdx 78 4 Guidelines Guidelines NNPS cord-334490-42gykxdx 78 5 Incidence Incidence NNP cord-334490-42gykxdx 78 6 of of IN cord-334490-42gykxdx 78 7 thrombotic thrombotic JJ cord-334490-42gykxdx 78 8 complications complication NNS cord-334490-42gykxdx 78 9 in in IN cord-334490-42gykxdx 78 10 critically critically RB cord-334490-42gykxdx 78 11 ill ill JJ cord-334490-42gykxdx 78 12 ICU ICU NNP cord-334490-42gykxdx 78 13 patients patient NNS cord-334490-42gykxdx 78 14 with with IN cord-334490-42gykxdx 78 15 COVID-19 COVID-19 NNP cord-334490-42gykxdx 78 16 Thromboembolism Thromboembolism NNP cord-334490-42gykxdx 78 17 andanticoagulanttherapy andanticoagulanttherapy NN cord-334490-42gykxdx 78 18 during during IN cord-334490-42gykxdx 78 19 theCOVID-19 thecovid-19 CD cord-334490-42gykxdx 78 20 pandemic pandemic NN cord-334490-42gykxdx 78 21 : : : cord-334490-42gykxdx 78 22 interim interim JJ cord-334490-42gykxdx 78 23 clinical clinical JJ cord-334490-42gykxdx 78 24 guidance guidance NN cord-334490-42gykxdx 78 25 from from IN cord-334490-42gykxdx 78 26 the the DT cord-334490-42gykxdx 78 27 anticoagulation anticoagulation NN cord-334490-42gykxdx 78 28 forum forum NN cord-334490-42gykxdx 78 29 ESC ESC NNP cord-334490-42gykxdx 78 30 Guidance Guidance NNP cord-334490-42gykxdx 78 31 for for IN cord-334490-42gykxdx 78 32 the the DT cord-334490-42gykxdx 78 33 Diagnosis Diagnosis NNP cord-334490-42gykxdx 78 34 and and CC cord-334490-42gykxdx 78 35 Management Management NNP cord-334490-42gykxdx 78 36 of of IN cord-334490-42gykxdx 78 37 CV CV NNP cord-334490-42gykxdx 78 38 Disease Disease NNP cord-334490-42gykxdx 78 39 during during IN cord-334490-42gykxdx 78 40 the the DT cord-334490-42gykxdx 78 41 COVID-19 COVID-19 NNP cord-334490-42gykxdx 78 42 Pandemic Pandemic NNP cord-334490-42gykxdx 78 43 Conflict Conflict NNP cord-334490-42gykxdx 78 44 of of IN cord-334490-42gykxdx 78 45 interest interest NN cord-334490-42gykxdx 78 46 A.A. A.A. NNP cord-334490-42gykxdx 78 47 Kammerlander Kammerlander NNP cord-334490-42gykxdx 78 48 and and CC cord-334490-42gykxdx 78 49 J. J. NNP cord-334490-42gykxdx 78 50 Mascherbauer Mascherbauer NNP cord-334490-42gykxdx 78 51 declare declare VBP cord-334490-42gykxdx 78 52 that that IN cord-334490-42gykxdx 78 53 they -PRON- PRP cord-334490-42gykxdx 78 54 have have VBP cord-334490-42gykxdx 78 55 no no DT cord-334490-42gykxdx 78 56 competing compete VBG cord-334490-42gykxdx 78 57 interests interest NNS cord-334490-42gykxdx 78 58 . . .