id sid tid token lemma pos cord-282256-lqmixm7s 1 1 key key NN cord-282256-lqmixm7s 1 2 : : : cord-282256-lqmixm7s 2 1 cord-282256-lqmixm7s cord-282256-lqmixm7s JJS cord-282256-lqmixm7s 2 2 authors author NNS cord-282256-lqmixm7s 2 3 : : : cord-282256-lqmixm7s 2 4 Tsioufis Tsioufis NNP cord-282256-lqmixm7s 2 5 , , , cord-282256-lqmixm7s 2 6 Costas Costas NNP cord-282256-lqmixm7s 2 7 ; ; : cord-282256-lqmixm7s 2 8 Dimitriadis Dimitriadis NNP cord-282256-lqmixm7s 2 9 , , , cord-282256-lqmixm7s 2 10 Kyriakos Kyriakos NNP cord-282256-lqmixm7s 2 11 ; ; : cord-282256-lqmixm7s 2 12 Tousoulis Tousoulis NNP cord-282256-lqmixm7s 2 13 , , , cord-282256-lqmixm7s 2 14 Dimitrios Dimitrios NNP cord-282256-lqmixm7s 2 15 title title NN cord-282256-lqmixm7s 2 16 : : : cord-282256-lqmixm7s 2 17 The the DT cord-282256-lqmixm7s 2 18 interplay interplay NN cord-282256-lqmixm7s 2 19 of of IN cord-282256-lqmixm7s 2 20 Hypertension hypertension NN cord-282256-lqmixm7s 2 21 , , , cord-282256-lqmixm7s 2 22 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 2 23 and and CC cord-282256-lqmixm7s 2 24 SARS SARS NNP cord-282256-lqmixm7s 2 25 - - HYPH cord-282256-lqmixm7s 2 26 CoV-2 CoV-2 NNP cord-282256-lqmixm7s 2 27 : : : cord-282256-lqmixm7s 2 28 Emerging emerge VBG cord-282256-lqmixm7s 2 29 data datum NNS cord-282256-lqmixm7s 2 30 as as IN cord-282256-lqmixm7s 2 31 the the DT cord-282256-lqmixm7s 2 32 “ " `` cord-282256-lqmixm7s 2 33 Ariadne Ariadne NNP cord-282256-lqmixm7s 2 34 ’s ’s POS cord-282256-lqmixm7s 2 35 thread thread NN cord-282256-lqmixm7s 2 36 ” " '' cord-282256-lqmixm7s 2 37 for for IN cord-282256-lqmixm7s 2 38 the the DT cord-282256-lqmixm7s 2 39 “ " `` cord-282256-lqmixm7s 2 40 labyrinth labyrinth NN cord-282256-lqmixm7s 2 41 ” " '' cord-282256-lqmixm7s 2 42 of of IN cord-282256-lqmixm7s 2 43 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 2 44 date date NN cord-282256-lqmixm7s 2 45 : : : cord-282256-lqmixm7s 2 46 2020 2020 CD cord-282256-lqmixm7s 2 47 - - HYPH cord-282256-lqmixm7s 2 48 05 05 CD cord-282256-lqmixm7s 2 49 - - HYPH cord-282256-lqmixm7s 2 50 22 22 CD cord-282256-lqmixm7s 2 51 journal journal NN cord-282256-lqmixm7s 2 52 : : : cord-282256-lqmixm7s 2 53 Hellenic Hellenic NNP cord-282256-lqmixm7s 2 54 J J NNP cord-282256-lqmixm7s 2 55 Cardiol Cardiol NNP cord-282256-lqmixm7s 2 56 DOI DOI NNP cord-282256-lqmixm7s 2 57 : : : cord-282256-lqmixm7s 3 1 10.1016 10.1016 CD cord-282256-lqmixm7s 3 2 / / SYM cord-282256-lqmixm7s 3 3 j.hjc.2020.05.003 j.hjc.2020.05.003 NNP cord-282256-lqmixm7s 3 4 sha sha NNP cord-282256-lqmixm7s 3 5 : : : cord-282256-lqmixm7s 3 6 33584a973478619ace6e2c45cab15569095577bb 33584a973478619ace6e2c45cab15569095577bb NNP cord-282256-lqmixm7s 3 7 doc_id doc_id NNP cord-282256-lqmixm7s 3 8 : : : cord-282256-lqmixm7s 3 9 282256 282256 CD cord-282256-lqmixm7s 3 10 cord_uid cord_uid NNS cord-282256-lqmixm7s 3 11 : : : cord-282256-lqmixm7s 4 1 lqmixm7s lqmixm7s NNP cord-282256-lqmixm7s 4 2 nan nan NNP cord-282256-lqmixm7s 4 3 Dr. Dr. NNP cord-282256-lqmixm7s 4 4 William William NNP cord-282256-lqmixm7s 4 5 H. H. NNP cord-282256-lqmixm7s 4 6 Stewart Stewart NNP cord-282256-lqmixm7s 4 7 the the DT cord-282256-lqmixm7s 4 8 US US NNP cord-282256-lqmixm7s 4 9 Surgeon Surgeon NNP cord-282256-lqmixm7s 4 10 General General NNP cord-282256-lqmixm7s 5 1 during during IN cord-282256-lqmixm7s 5 2 1965 1965 CD cord-282256-lqmixm7s 5 3 - - SYM cord-282256-lqmixm7s 5 4 1969 1969 CD cord-282256-lqmixm7s 5 5 is be VBZ cord-282256-lqmixm7s 5 6 remembered remember VBN cord-282256-lqmixm7s 5 7 primarily primarily RB cord-282256-lqmixm7s 5 8 for for IN cord-282256-lqmixm7s 5 9 his -PRON- PRP$ cord-282256-lqmixm7s 5 10 infamous infamous JJ cord-282256-lqmixm7s 5 11 statement statement NN cord-282256-lqmixm7s 5 12 : : : cord-282256-lqmixm7s 5 13 " " `` cord-282256-lqmixm7s 5 14 It -PRON- PRP cord-282256-lqmixm7s 5 15 is be VBZ cord-282256-lqmixm7s 5 16 time time NN cord-282256-lqmixm7s 5 17 to to TO cord-282256-lqmixm7s 5 18 close close VB cord-282256-lqmixm7s 5 19 the the DT cord-282256-lqmixm7s 5 20 book book NN cord-282256-lqmixm7s 5 21 on on IN cord-282256-lqmixm7s 5 22 infectious infectious JJ cord-282256-lqmixm7s 5 23 diseases disease NNS cord-282256-lqmixm7s 5 24 … … NFP cord-282256-lqmixm7s 6 1 " " `` cord-282256-lqmixm7s 6 2 Five five CD cord-282256-lqmixm7s 6 3 decades decade NNS cord-282256-lqmixm7s 6 4 later later RB cord-282256-lqmixm7s 6 5 , , , cord-282256-lqmixm7s 6 6 how how WRB cord-282256-lqmixm7s 6 7 erroneous erroneous JJ cord-282256-lqmixm7s 6 8 this this DT cord-282256-lqmixm7s 6 9 statement statement NN cord-282256-lqmixm7s 6 10 was be VBD cord-282256-lqmixm7s 6 11 ! ! . cord-282256-lqmixm7s 7 1 In in IN cord-282256-lqmixm7s 7 2 2020 2020 CD cord-282256-lqmixm7s 7 3 , , , cord-282256-lqmixm7s 7 4 humanity humanity NN cord-282256-lqmixm7s 7 5 is be VBZ cord-282256-lqmixm7s 7 6 facing face VBG cord-282256-lqmixm7s 7 7 one one CD cord-282256-lqmixm7s 7 8 of of IN cord-282256-lqmixm7s 7 9 the the DT cord-282256-lqmixm7s 7 10 most most RBS cord-282256-lqmixm7s 7 11 devastating devastating JJ cord-282256-lqmixm7s 7 12 health health NN cord-282256-lqmixm7s 7 13 urgencies urgency NNS cord-282256-lqmixm7s 7 14 in in IN cord-282256-lqmixm7s 7 15 known know VBN cord-282256-lqmixm7s 7 16 modern modern JJ cord-282256-lqmixm7s 7 17 history history NN cord-282256-lqmixm7s 7 18 leading lead VBG cord-282256-lqmixm7s 7 19 to to IN cord-282256-lqmixm7s 7 20 health health NN cord-282256-lqmixm7s 7 21 system system NN cord-282256-lqmixm7s 7 22 collapse collapse NN cord-282256-lqmixm7s 7 23 , , , cord-282256-lqmixm7s 7 24 economies economy NNS cord-282256-lqmixm7s 7 25 " " `` cord-282256-lqmixm7s 7 26 shutting shut VBG cord-282256-lqmixm7s 7 27 down down RP cord-282256-lqmixm7s 7 28 " " '' cord-282256-lqmixm7s 7 29 , , , cord-282256-lqmixm7s 7 30 unemployment unemployment NN cord-282256-lqmixm7s 7 31 surges surge NNS cord-282256-lqmixm7s 7 32 and and CC cord-282256-lqmixm7s 7 33 thousands thousand NNS cord-282256-lqmixm7s 7 34 of of IN cord-282256-lqmixm7s 7 35 deaths death NNS cord-282256-lqmixm7s 7 36 worldwide worldwide RB cord-282256-lqmixm7s 7 37 due due IN cord-282256-lqmixm7s 7 38 to to IN cord-282256-lqmixm7s 7 39 COVID-19 covid-19 JJ cord-282256-lqmixm7s 7 40 infection infection NN cord-282256-lqmixm7s 7 41 . . . cord-282256-lqmixm7s 8 1 1 1 LS cord-282256-lqmixm7s 9 1 For for IN cord-282256-lqmixm7s 9 2 the the DT cord-282256-lqmixm7s 9 3 cardiovascular cardiovascular JJ cord-282256-lqmixm7s 9 4 medical medical JJ cord-282256-lqmixm7s 9 5 community community NN cord-282256-lqmixm7s 9 6 there there EX cord-282256-lqmixm7s 9 7 are be VBP cord-282256-lqmixm7s 9 8 important important JJ cord-282256-lqmixm7s 9 9 issues issue NNS cord-282256-lqmixm7s 9 10 to to TO cord-282256-lqmixm7s 9 11 be be VB cord-282256-lqmixm7s 9 12 clarified clarify VBN cord-282256-lqmixm7s 9 13 and and CC cord-282256-lqmixm7s 9 14 in in IN cord-282256-lqmixm7s 9 15 this this DT cord-282256-lqmixm7s 9 16 editorial editorial NN cord-282256-lqmixm7s 9 17 our -PRON- PRP$ cord-282256-lqmixm7s 9 18 attempt attempt NN cord-282256-lqmixm7s 9 19 is be VBZ cord-282256-lqmixm7s 9 20 to to TO cord-282256-lqmixm7s 9 21 provide provide VB cord-282256-lqmixm7s 9 22 the the DT cord-282256-lqmixm7s 9 23 latest late JJS cord-282256-lqmixm7s 9 24 evidence evidence NN cord-282256-lqmixm7s 9 25 - - HYPH cord-282256-lqmixm7s 9 26 based base VBN cord-282256-lqmixm7s 9 27 directions direction NNS cord-282256-lqmixm7s 9 28 for for IN cord-282256-lqmixm7s 9 29 the the DT cord-282256-lqmixm7s 9 30 intriguing intriguing JJ cord-282256-lqmixm7s 9 31 labyrinth labyrinth NN cord-282256-lqmixm7s 9 32 - - HYPH cord-282256-lqmixm7s 9 33 like like JJ cord-282256-lqmixm7s 9 34 associations association NNS cord-282256-lqmixm7s 9 35 of of IN cord-282256-lqmixm7s 9 36 hypertension hypertension NN cord-282256-lqmixm7s 9 37 , , , cord-282256-lqmixm7s 9 38 reninangiotensin reninangiotensin NNP cord-282256-lqmixm7s 9 39 system system NN cord-282256-lqmixm7s 9 40 and and CC cord-282256-lqmixm7s 9 41 COVID-19 covid-19 NN cord-282256-lqmixm7s 9 42 . . . cord-282256-lqmixm7s 10 1 The the DT cord-282256-lqmixm7s 10 2 hype hype NN cord-282256-lqmixm7s 10 3 of of IN cord-282256-lqmixm7s 10 4 the the DT cord-282256-lqmixm7s 10 5 hypertension hypertension NN cord-282256-lqmixm7s 10 6 link link NN cord-282256-lqmixm7s 10 7 to to IN cord-282256-lqmixm7s 10 8 COVID-19 covid-19 JJ cord-282256-lqmixm7s 10 9 pandemic pandemic NN cord-282256-lqmixm7s 10 10 was be VBD cord-282256-lqmixm7s 10 11 fueled fuel VBN cord-282256-lqmixm7s 10 12 by by IN cord-282256-lqmixm7s 10 13 the the DT cord-282256-lqmixm7s 10 14 initial initial JJ cord-282256-lqmixm7s 10 15 reports report NNS cord-282256-lqmixm7s 10 16 from from IN cord-282256-lqmixm7s 10 17 Wuhan Wuhan NNP cord-282256-lqmixm7s 10 18 , , , cord-282256-lqmixm7s 10 19 China China NNP cord-282256-lqmixm7s 10 20 , , , cord-282256-lqmixm7s 10 21 in in IN cord-282256-lqmixm7s 10 22 which which WDT cord-282256-lqmixm7s 10 23 hypertension hypertension NN cord-282256-lqmixm7s 10 24 was be VBD cord-282256-lqmixm7s 10 25 present present JJ cord-282256-lqmixm7s 10 26 in in IN cord-282256-lqmixm7s 10 27 30 30 CD cord-282256-lqmixm7s 10 28 % % NN cord-282256-lqmixm7s 10 29 of of IN cord-282256-lqmixm7s 10 30 cases case NNS cord-282256-lqmixm7s 10 31 and and CC cord-282256-lqmixm7s 10 32 in in IN cord-282256-lqmixm7s 10 33 48 48 CD cord-282256-lqmixm7s 10 34 % % NN cord-282256-lqmixm7s 10 35 of of IN cord-282256-lqmixm7s 10 36 non non NNS cord-282256-lqmixm7s 10 37 - - NNS cord-282256-lqmixm7s 10 38 survivors survivor NNS cord-282256-lqmixm7s 10 39 . . . cord-282256-lqmixm7s 11 1 2 2 LS cord-282256-lqmixm7s 12 1 In in IN cord-282256-lqmixm7s 12 2 138 138 CD cord-282256-lqmixm7s 12 3 hospitalized hospitalize VBN cord-282256-lqmixm7s 12 4 patients patient NNS cord-282256-lqmixm7s 12 5 with with IN cord-282256-lqmixm7s 12 6 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 12 7 , , , cord-282256-lqmixm7s 12 8 hypertension hypertension NN cord-282256-lqmixm7s 12 9 was be VBD cord-282256-lqmixm7s 12 10 observed observe VBN cord-282256-lqmixm7s 12 11 in in IN cord-282256-lqmixm7s 12 12 31 31 CD cord-282256-lqmixm7s 12 13 % % NN cord-282256-lqmixm7s 12 14 ( ( -LRB- cord-282256-lqmixm7s 12 15 58 58 CD cord-282256-lqmixm7s 12 16 % % NN cord-282256-lqmixm7s 12 17 in in IN cord-282256-lqmixm7s 12 18 intensive intensive JJ cord-282256-lqmixm7s 12 19 units unit NNS cord-282256-lqmixm7s 12 20 ) ) -RRB- cord-282256-lqmixm7s 13 1 3 3 CD cord-282256-lqmixm7s 13 2 and and CC cord-282256-lqmixm7s 13 3 the the DT cord-282256-lqmixm7s 13 4 official official JJ cord-282256-lqmixm7s 13 5 data datum NNS cord-282256-lqmixm7s 13 6 from from IN cord-282256-lqmixm7s 13 7 the the DT cord-282256-lqmixm7s 13 8 National National NNP cord-282256-lqmixm7s 13 9 Health Health NNP cord-282256-lqmixm7s 13 10 Commission Commission NNP cord-282256-lqmixm7s 13 11 of of IN cord-282256-lqmixm7s 13 12 China China NNP cord-282256-lqmixm7s 13 13 demonstrate demonstrate VBP cord-282256-lqmixm7s 13 14 that that IN cord-282256-lqmixm7s 13 15 35 35 CD cord-282256-lqmixm7s 13 16 % % NN cord-282256-lqmixm7s 13 17 of of IN cord-282256-lqmixm7s 13 18 patients patient NNS cord-282256-lqmixm7s 13 19 diagnosed diagnose VBN cord-282256-lqmixm7s 13 20 with with IN cord-282256-lqmixm7s 13 21 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 13 22 have have VBP cord-282256-lqmixm7s 13 23 hypertension hypertension NN cord-282256-lqmixm7s 13 24 with with IN cord-282256-lqmixm7s 13 25 the the DT cord-282256-lqmixm7s 13 26 overall overall JJ cord-282256-lqmixm7s 13 27 case case NN cord-282256-lqmixm7s 13 28 fatality fatality NN cord-282256-lqmixm7s 13 29 rate rate NN cord-282256-lqmixm7s 13 30 being be VBG cord-282256-lqmixm7s 13 31 2.3 2.3 CD cord-282256-lqmixm7s 13 32 % % NN cord-282256-lqmixm7s 13 33 in in IN cord-282256-lqmixm7s 13 34 the the DT cord-282256-lqmixm7s 13 35 entire entire JJ cord-282256-lqmixm7s 13 36 cohort cohort NN cord-282256-lqmixm7s 13 37 but but CC cord-282256-lqmixm7s 13 38 significantly significantly RB cord-282256-lqmixm7s 13 39 higher high JJR cord-282256-lqmixm7s 13 40 ( ( -LRB- cord-282256-lqmixm7s 13 41 6 6 CD cord-282256-lqmixm7s 13 42 % % NN cord-282256-lqmixm7s 13 43 ) ) -RRB- cord-282256-lqmixm7s 13 44 in in IN cord-282256-lqmixm7s 13 45 patients patient NNS cord-282256-lqmixm7s 13 46 with with IN cord-282256-lqmixm7s 13 47 hypertension hypertension NN cord-282256-lqmixm7s 13 48 . . . cord-282256-lqmixm7s 14 1 4 4 LS cord-282256-lqmixm7s 15 1 The the DT cord-282256-lqmixm7s 15 2 only only JJ cord-282256-lqmixm7s 15 3 available available JJ cord-282256-lqmixm7s 15 4 meta meta NN cord-282256-lqmixm7s 15 5 - - HYPH cord-282256-lqmixm7s 15 6 analysis analysis NN cord-282256-lqmixm7s 15 7 from from IN cord-282256-lqmixm7s 15 8 Wuhan Wuhan NNP cord-282256-lqmixm7s 15 9 of of IN cord-282256-lqmixm7s 15 10 46248 46248 CD cord-282256-lqmixm7s 15 11 cases case NNS cord-282256-lqmixm7s 15 12 , , , cord-282256-lqmixm7s 15 13 supports support VBZ cord-282256-lqmixm7s 15 14 that that IN cord-282256-lqmixm7s 15 15 hypertension hypertension NN cord-282256-lqmixm7s 15 16 constitutes constitute VBZ cord-282256-lqmixm7s 15 17 the the DT cord-282256-lqmixm7s 15 18 most most RBS cord-282256-lqmixm7s 15 19 prevalent prevalent JJ cord-282256-lqmixm7s 15 20 comorbidity comorbidity NN cord-282256-lqmixm7s 15 21 in in IN cord-282256-lqmixm7s 15 22 17 17 CD cord-282256-lqmixm7s 15 23 % % NN cord-282256-lqmixm7s 15 24 of of IN cord-282256-lqmixm7s 15 25 patients patient NNS cord-282256-lqmixm7s 15 26 infected infect VBN cord-282256-lqmixm7s 15 27 with with IN cord-282256-lqmixm7s 15 28 the the DT cord-282256-lqmixm7s 15 29 novel novel JJ cord-282256-lqmixm7s 15 30 coronavirus coronavirus NN cord-282256-lqmixm7s 15 31 . . . cord-282256-lqmixm7s 16 1 5 5 LS cord-282256-lqmixm7s 17 1 The the DT cord-282256-lqmixm7s 17 2 globality globality NN cord-282256-lqmixm7s 17 3 of of IN cord-282256-lqmixm7s 17 4 the the DT cord-282256-lqmixm7s 17 5 pandemic pandemic NN cord-282256-lqmixm7s 17 6 stresses stress VBZ cord-282256-lqmixm7s 17 7 the the DT cord-282256-lqmixm7s 17 8 need need NN cord-282256-lqmixm7s 17 9 for for IN cord-282256-lqmixm7s 17 10 international international JJ cord-282256-lqmixm7s 17 11 data datum NNS cord-282256-lqmixm7s 17 12 . . . cord-282256-lqmixm7s 18 1 In in IN cord-282256-lqmixm7s 18 2 Italy Italy NNP cord-282256-lqmixm7s 18 3 the the DT cord-282256-lqmixm7s 18 4 most most RBS cord-282256-lqmixm7s 18 5 current current JJ cord-282256-lqmixm7s 18 6 analysis analysis NN cord-282256-lqmixm7s 18 7 shows show VBZ cord-282256-lqmixm7s 18 8 that that DT cord-282256-lqmixm7s 18 9 of of IN cord-282256-lqmixm7s 18 10 69.1 69.1 CD cord-282256-lqmixm7s 18 11 % % NN cord-282256-lqmixm7s 18 12 of of IN cord-282256-lqmixm7s 18 13 the the DT cord-282256-lqmixm7s 18 14 deceased deceased JJ cord-282256-lqmixm7s 18 15 patients patient NNS cord-282256-lqmixm7s 18 16 were be VBD cord-282256-lqmixm7s 18 17 hypertensives hypertensive NNS cord-282256-lqmixm7s 18 18 and and CC cord-282256-lqmixm7s 18 19 30 30 CD cord-282256-lqmixm7s 18 20 % % NN cord-282256-lqmixm7s 18 21 used use VBN cord-282256-lqmixm7s 18 22 angiotensin angiotensin NN cord-282256-lqmixm7s 18 23 converting convert VBG cord-282256-lqmixm7s 18 24 enzyme enzyme NN cord-282256-lqmixm7s 18 25 inhibitors inhibitor NNS cord-282256-lqmixm7s 18 26 ( ( -LRB- cord-282256-lqmixm7s 18 27 ACEIs acei NNS cord-282256-lqmixm7s 18 28 ) ) -RRB- cord-282256-lqmixm7s 18 29 and and CC cord-282256-lqmixm7s 18 30 17 17 CD cord-282256-lqmixm7s 18 31 % % NN cord-282256-lqmixm7s 18 32 angiotensin angiotensin NN cord-282256-lqmixm7s 18 33 receptor receptor NN cord-282256-lqmixm7s 18 34 blockers blocker NNS cord-282256-lqmixm7s 18 35 ( ( -LRB- cord-282256-lqmixm7s 18 36 ARBs arb NNS cord-282256-lqmixm7s 18 37 ) ) -RRB- cord-282256-lqmixm7s 18 38 . . . cord-282256-lqmixm7s 19 1 6 6 CD cord-282256-lqmixm7s 20 1 Despite despite IN cord-282256-lqmixm7s 20 2 the the DT cord-282256-lqmixm7s 20 3 above above JJ cord-282256-lqmixm7s 20 4 observations observation NNS cord-282256-lqmixm7s 20 5 , , , cord-282256-lqmixm7s 20 6 there there EX cord-282256-lqmixm7s 20 7 are be VBP cord-282256-lqmixm7s 20 8 no no DT cord-282256-lqmixm7s 20 9 robust robust JJ cord-282256-lqmixm7s 20 10 data datum NNS cord-282256-lqmixm7s 20 11 to to TO cord-282256-lqmixm7s 20 12 suggest suggest VB cord-282256-lqmixm7s 20 13 clearly clearly RB cord-282256-lqmixm7s 20 14 an an DT cord-282256-lqmixm7s 20 15 independent independent JJ cord-282256-lqmixm7s 20 16 link link NN cord-282256-lqmixm7s 20 17 of of IN cord-282256-lqmixm7s 20 18 hypertension hypertension NN cord-282256-lqmixm7s 20 19 with with IN cord-282256-lqmixm7s 20 20 increased increase VBN cord-282256-lqmixm7s 20 21 COVID-19 covid-19 JJ cord-282256-lqmixm7s 20 22 morbidity morbidity NN cord-282256-lqmixm7s 20 23 and and CC cord-282256-lqmixm7s 20 24 mortality mortality NN cord-282256-lqmixm7s 20 25 . . . cord-282256-lqmixm7s 21 1 7 7 CD cord-282256-lqmixm7s 22 1 Similarly similarly RB cord-282256-lqmixm7s 22 2 , , , cord-282256-lqmixm7s 22 3 in in IN cord-282256-lqmixm7s 22 4 other other JJ cord-282256-lqmixm7s 22 5 lower low JJR cord-282256-lqmixm7s 22 6 respiratory respiratory JJ cord-282256-lqmixm7s 22 7 track track NN cord-282256-lqmixm7s 22 8 infections infection NNS cord-282256-lqmixm7s 22 9 , , , cord-282256-lqmixm7s 22 10 diabetes diabetes NN cord-282256-lqmixm7s 22 11 and and CC cord-282256-lqmixm7s 22 12 heart heart NN cord-282256-lqmixm7s 22 13 failure failure NN cord-282256-lqmixm7s 22 14 are be VBP cord-282256-lqmixm7s 22 15 independently independently RB cord-282256-lqmixm7s 22 16 related relate VBN cord-282256-lqmixm7s 22 17 to to IN cord-282256-lqmixm7s 22 18 adverse adverse JJ cord-282256-lqmixm7s 22 19 outcome outcome NN cord-282256-lqmixm7s 22 20 , , , cord-282256-lqmixm7s 22 21 while while IN cord-282256-lqmixm7s 22 22 hypertension hypertension NN cord-282256-lqmixm7s 22 23 per per FW cord-282256-lqmixm7s 22 24 se se FW cord-282256-lqmixm7s 22 25 is be VBZ cord-282256-lqmixm7s 22 26 not not RB cord-282256-lqmixm7s 22 27 . . . cord-282256-lqmixm7s 23 1 7 7 CD cord-282256-lqmixm7s 23 2 Major major JJ cord-282256-lqmixm7s 23 3 pathophysiological pathophysiological JJ cord-282256-lqmixm7s 23 4 pathways pathway NNS cord-282256-lqmixm7s 23 5 by by IN cord-282256-lqmixm7s 23 6 which which WDT cord-282256-lqmixm7s 23 7 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 23 8 causes cause VBZ cord-282256-lqmixm7s 23 9 cardiovascular cardiovascular JJ cord-282256-lqmixm7s 23 10 and and CC cord-282256-lqmixm7s 23 11 systemic systemic JJ cord-282256-lqmixm7s 23 12 complications complication NNS cord-282256-lqmixm7s 23 13 is be VBZ cord-282256-lqmixm7s 23 14 diffuse diffuse VB cord-282256-lqmixm7s 23 15 inflammatory inflammatory JJ cord-282256-lqmixm7s 23 16 response response NN cord-282256-lqmixm7s 23 17 and and CC cord-282256-lqmixm7s 23 18 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 24 1 ( ( -LRB- cord-282256-lqmixm7s 24 2 Figure figure NN cord-282256-lqmixm7s 24 3 1 1 CD cord-282256-lqmixm7s 24 4 ) ) -RRB- cord-282256-lqmixm7s 24 5 . . . cord-282256-lqmixm7s 25 1 The the DT cord-282256-lqmixm7s 25 2 characteristic characteristic JJ cord-282256-lqmixm7s 25 3 COVID-19 covid-19 CD cord-282256-lqmixm7s 25 4 " " `` cord-282256-lqmixm7s 25 5 cytokine cytokine NN cord-282256-lqmixm7s 25 6 storm storm NN cord-282256-lqmixm7s 25 7 " " '' cord-282256-lqmixm7s 25 8 is be VBZ cord-282256-lqmixm7s 25 9 reflected reflect VBN cord-282256-lqmixm7s 25 10 by by IN cord-282256-lqmixm7s 25 11 increased increase VBN cord-282256-lqmixm7s 25 12 IL-17 IL-17 NNP cord-282256-lqmixm7s 25 13 , , , cord-282256-lqmixm7s 25 14 IL-7 IL-7 NNP cord-282256-lqmixm7s 25 15 , , , cord-282256-lqmixm7s 25 16 IL-6 IL-6 NNP cord-282256-lqmixm7s 25 17 , , , cord-282256-lqmixm7s 25 18 interferon interferon NN cord-282256-lqmixm7s 25 19 - - HYPH cord-282256-lqmixm7s 25 20 c c NNP cord-282256-lqmixm7s 25 21 , , , cord-282256-lqmixm7s 25 22 and and CC cord-282256-lqmixm7s 25 23 TNFa TNFa NNP cord-282256-lqmixm7s 25 24 . . . cord-282256-lqmixm7s 26 1 7 7 CD cord-282256-lqmixm7s 26 2 , , , cord-282256-lqmixm7s 26 3 8 8 CD cord-282256-lqmixm7s 26 4 Focusing focus VBG cord-282256-lqmixm7s 26 5 on on IN cord-282256-lqmixm7s 26 6 IL-6 IL-6 NNP cord-282256-lqmixm7s 27 1 it -PRON- PRP cord-282256-lqmixm7s 27 2 is be VBZ cord-282256-lqmixm7s 27 3 associated associate VBN cord-282256-lqmixm7s 27 4 with with IN cord-282256-lqmixm7s 27 5 the the DT cord-282256-lqmixm7s 27 6 outcome outcome NN cord-282256-lqmixm7s 27 7 from from IN cord-282256-lqmixm7s 27 8 the the DT cord-282256-lqmixm7s 27 9 viral viral JJ cord-282256-lqmixm7s 27 10 infection infection NN cord-282256-lqmixm7s 27 11 and and CC cord-282256-lqmixm7s 27 12 also also RB cord-282256-lqmixm7s 27 13 plays play VBZ cord-282256-lqmixm7s 27 14 a a DT cord-282256-lqmixm7s 27 15 key key JJ cord-282256-lqmixm7s 27 16 regulator regulator NN cord-282256-lqmixm7s 27 17 role role NN cord-282256-lqmixm7s 27 18 of of IN cord-282256-lqmixm7s 27 19 immuneinflammatory immuneinflammatory NNP cord-282256-lqmixm7s 27 20 response response NN cord-282256-lqmixm7s 27 21 in in IN cord-282256-lqmixm7s 27 22 essential essential JJ cord-282256-lqmixm7s 27 23 hypertension hypertension NN cord-282256-lqmixm7s 27 24 . . . cord-282256-lqmixm7s 28 1 7 7 CD cord-282256-lqmixm7s 29 1 Supportive supportive JJ cord-282256-lqmixm7s 29 2 to to IN cord-282256-lqmixm7s 29 3 the the DT cord-282256-lqmixm7s 29 4 latter latter JJ cord-282256-lqmixm7s 30 1 , , , cord-282256-lqmixm7s 30 2 hypertension hypertension NN cord-282256-lqmixm7s 30 3 pathogenesis pathogenesis NN cord-282256-lqmixm7s 30 4 and and CC cord-282256-lqmixm7s 30 5 progression progression NN cord-282256-lqmixm7s 30 6 of of IN cord-282256-lqmixm7s 30 7 target target NN cord-282256-lqmixm7s 30 8 organ organ NN cord-282256-lqmixm7s 30 9 damage damage NN cord-282256-lqmixm7s 30 10 is be VBZ cord-282256-lqmixm7s 30 11 closely closely RB cord-282256-lqmixm7s 30 12 associated associate VBN cord-282256-lqmixm7s 30 13 with with IN cord-282256-lqmixm7s 30 14 low low JJ cord-282256-lqmixm7s 30 15 - - HYPH cord-282256-lqmixm7s 30 16 grade grade NN cord-282256-lqmixm7s 30 17 inflammation inflammation NN cord-282256-lqmixm7s 30 18 9 9 CD cord-282256-lqmixm7s 30 19 and and CC cord-282256-lqmixm7s 30 20 this this DT cord-282256-lqmixm7s 30 21 could could MD cord-282256-lqmixm7s 30 22 partially partially RB cord-282256-lqmixm7s 30 23 explain explain VB cord-282256-lqmixm7s 30 24 the the DT cord-282256-lqmixm7s 30 25 fact fact NN cord-282256-lqmixm7s 30 26 that that IN cord-282256-lqmixm7s 30 27 hypertension hypertension NN cord-282256-lqmixm7s 30 28 is be VBZ cord-282256-lqmixm7s 30 29 the the DT cord-282256-lqmixm7s 30 30 most most RBS cord-282256-lqmixm7s 30 31 common common JJ cord-282256-lqmixm7s 30 32 comorbidity comorbidity NN cord-282256-lqmixm7s 30 33 in in IN cord-282256-lqmixm7s 30 34 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 30 35 cohorts cohort NNS cord-282256-lqmixm7s 30 36 and and CC cord-282256-lqmixm7s 30 37 related relate VBN cord-282256-lqmixm7s 30 38 to to IN cord-282256-lqmixm7s 30 39 worst bad JJS cord-282256-lqmixm7s 30 40 course course NN cord-282256-lqmixm7s 30 41 of of IN cord-282256-lqmixm7s 30 42 the the DT cord-282256-lqmixm7s 30 43 infection infection NN cord-282256-lqmixm7s 30 44 . . . cord-282256-lqmixm7s 31 1 7 7 CD cord-282256-lqmixm7s 32 1 The the DT cord-282256-lqmixm7s 32 2 confounding confounding JJ cord-282256-lqmixm7s 32 3 effect effect NN cord-282256-lqmixm7s 32 4 , , , cord-282256-lqmixm7s 32 5 however however RB cord-282256-lqmixm7s 32 6 , , , cord-282256-lqmixm7s 32 7 of of IN cord-282256-lqmixm7s 32 8 ageing age VBG cord-282256-lqmixm7s 32 9 and and CC cord-282256-lqmixm7s 32 10 other other JJ cord-282256-lqmixm7s 32 11 comorbidities comorbiditie NNS cord-282256-lqmixm7s 32 12 like like IN cord-282256-lqmixm7s 32 13 diabetes diabetes NN cord-282256-lqmixm7s 32 14 and and CC cord-282256-lqmixm7s 32 15 renal renal JJ cord-282256-lqmixm7s 32 16 dysfunction dysfunction NN cord-282256-lqmixm7s 32 17 in in IN cord-282256-lqmixm7s 32 18 this this DT cord-282256-lqmixm7s 32 19 inflammatory inflammatory JJ cord-282256-lqmixm7s 32 20 link link NN cord-282256-lqmixm7s 32 21 should should MD cord-282256-lqmixm7s 32 22 be be VB cord-282256-lqmixm7s 32 23 taken take VBN cord-282256-lqmixm7s 32 24 in in IN cord-282256-lqmixm7s 32 25 mind mind NN cord-282256-lqmixm7s 32 26 with with IN cord-282256-lqmixm7s 32 27 future future JJ cord-282256-lqmixm7s 32 28 studies study NNS cord-282256-lqmixm7s 32 29 urgently urgently RB cord-282256-lqmixm7s 32 30 needed need VBN cord-282256-lqmixm7s 32 31 in in IN cord-282256-lqmixm7s 32 32 this this DT cord-282256-lqmixm7s 32 33 setting setting NN cord-282256-lqmixm7s 32 34 . . . cord-282256-lqmixm7s 33 1 In in IN cord-282256-lqmixm7s 33 2 humans human NNS cord-282256-lqmixm7s 33 3 , , , cord-282256-lqmixm7s 33 4 the the DT cord-282256-lqmixm7s 33 5 entry entry NN cord-282256-lqmixm7s 33 6 of of IN cord-282256-lqmixm7s 33 7 the the DT cord-282256-lqmixm7s 33 8 new new JJ cord-282256-lqmixm7s 33 9 coronavirus coronavirus NN cord-282256-lqmixm7s 33 10 into into IN cord-282256-lqmixm7s 33 11 the the DT cord-282256-lqmixm7s 33 12 target target NN cord-282256-lqmixm7s 33 13 cells cell NNS cord-282256-lqmixm7s 33 14 is be VBZ cord-282256-lqmixm7s 33 15 facilitated facilitate VBN cord-282256-lqmixm7s 33 16 by by IN cord-282256-lqmixm7s 33 17 the the DT cord-282256-lqmixm7s 33 18 spike spike NN cord-282256-lqmixm7s 33 19 protein protein NN cord-282256-lqmixm7s 33 20 that that WDT cord-282256-lqmixm7s 33 21 is be VBZ cord-282256-lqmixm7s 33 22 anchored anchor VBN cord-282256-lqmixm7s 33 23 to to IN cord-282256-lqmixm7s 33 24 the the DT cord-282256-lqmixm7s 33 25 angiotensin angiotensin NN cord-282256-lqmixm7s 33 26 converting convert VBG cord-282256-lqmixm7s 33 27 enzyme-2 enzyme-2 NNP cord-282256-lqmixm7s 33 28 ( ( -LRB- cord-282256-lqmixm7s 33 29 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 33 30 ) ) -RRB- cord-282256-lqmixm7s 33 31 in in IN cord-282256-lqmixm7s 33 32 parallel parallel NN cord-282256-lqmixm7s 33 33 with with IN cord-282256-lqmixm7s 33 34 cellular cellular JJ cord-282256-lqmixm7s 33 35 serine serine NN cord-282256-lqmixm7s 33 36 protease protease NN cord-282256-lqmixm7s 33 37 TMPRSS2 TMPRSS2 NNP cord-282256-lqmixm7s 33 38 actions action NNS cord-282256-lqmixm7s 33 39 . . . cord-282256-lqmixm7s 34 1 7 7 CD cord-282256-lqmixm7s 34 2 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 34 3 converts convert VBZ cord-282256-lqmixm7s 34 4 angiotensin angiotensin NN cord-282256-lqmixm7s 34 5 II II NNP cord-282256-lqmixm7s 34 6 to to IN cord-282256-lqmixm7s 34 7 angiotensin angiotensin NN cord-282256-lqmixm7s 34 8 1 1 CD cord-282256-lqmixm7s 34 9 - - SYM cord-282256-lqmixm7s 34 10 7 7 CD cord-282256-lqmixm7s 34 11 ( ( -LRB- cord-282256-lqmixm7s 34 12 Figure figure NN cord-282256-lqmixm7s 34 13 1 1 CD cord-282256-lqmixm7s 34 14 ) ) -RRB- cord-282256-lqmixm7s 34 15 . . . cord-282256-lqmixm7s 35 1 10 10 CD cord-282256-lqmixm7s 35 2 , , , cord-282256-lqmixm7s 35 3 11 11 CD cord-282256-lqmixm7s 35 4 Receptors receptor NNS cord-282256-lqmixm7s 35 5 of of IN cord-282256-lqmixm7s 35 6 the the DT cord-282256-lqmixm7s 35 7 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 35 8 are be VBP cord-282256-lqmixm7s 35 9 expressed express VBN cord-282256-lqmixm7s 35 10 in in IN cord-282256-lqmixm7s 35 11 the the DT cord-282256-lqmixm7s 35 12 epithelial epithelial JJ cord-282256-lqmixm7s 35 13 cells cell NNS cord-282256-lqmixm7s 35 14 of of IN cord-282256-lqmixm7s 35 15 lungs lung NNS cord-282256-lqmixm7s 35 16 , , , cord-282256-lqmixm7s 35 17 intestine intestine NN cord-282256-lqmixm7s 35 18 , , , cord-282256-lqmixm7s 35 19 kidneys kidney NNS cord-282256-lqmixm7s 35 20 , , , cord-282256-lqmixm7s 35 21 heart heart NN cord-282256-lqmixm7s 35 22 and and CC cord-282256-lqmixm7s 35 23 vessels vessel NNS cord-282256-lqmixm7s 35 24 and and CC cord-282256-lqmixm7s 35 25 their -PRON- PRP$ cord-282256-lqmixm7s 35 26 activation activation NN cord-282256-lqmixm7s 35 27 causes cause VBZ cord-282256-lqmixm7s 35 28 vascular vascular JJ cord-282256-lqmixm7s 35 29 dilatation dilatation NN cord-282256-lqmixm7s 35 30 and and CC cord-282256-lqmixm7s 35 31 provide provide VB cord-282256-lqmixm7s 35 32 renal renal JJ cord-282256-lqmixm7s 35 33 and and CC cord-282256-lqmixm7s 35 34 cardiovascular cardiovascular JJ cord-282256-lqmixm7s 35 35 protection protection NN cord-282256-lqmixm7s 35 36 . . . cord-282256-lqmixm7s 36 1 7 7 CD cord-282256-lqmixm7s 36 2 , , , cord-282256-lqmixm7s 36 3 10 10 CD cord-282256-lqmixm7s 36 4 , , , cord-282256-lqmixm7s 36 5 11 11 CD cord-282256-lqmixm7s 37 1 In in IN cord-282256-lqmixm7s 37 2 this this DT cord-282256-lqmixm7s 37 3 sense sense NN cord-282256-lqmixm7s 37 4 promoters promoter NNS cord-282256-lqmixm7s 37 5 of of IN cord-282256-lqmixm7s 37 6 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 37 7 are be VBP cord-282256-lqmixm7s 37 8 studied study VBN cord-282256-lqmixm7s 37 9 as as IN cord-282256-lqmixm7s 37 10 potential potential JJ cord-282256-lqmixm7s 37 11 antihypertensive antihypertensive JJ cord-282256-lqmixm7s 37 12 drugs drug NNS cord-282256-lqmixm7s 37 13 . . . cord-282256-lqmixm7s 38 1 10 10 CD cord-282256-lqmixm7s 38 2 , , , cord-282256-lqmixm7s 38 3 11 11 CD cord-282256-lqmixm7s 39 1 The the DT cord-282256-lqmixm7s 39 2 novel novel JJ cord-282256-lqmixm7s 39 3 coronavirus coronavirus NN cord-282256-lqmixm7s 39 4 SARS SARS NNP cord-282256-lqmixm7s 39 5 - - HYPH cord-282256-lqmixm7s 39 6 CoV2 CoV2 NNS cord-282256-lqmixm7s 39 7 by by IN cord-282256-lqmixm7s 39 8 using use VBG cord-282256-lqmixm7s 39 9 the the DT cord-282256-lqmixm7s 39 10 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 39 11 " " `` cord-282256-lqmixm7s 39 12 consumes consume VBZ cord-282256-lqmixm7s 39 13 " " '' cord-282256-lqmixm7s 39 14 the the DT cord-282256-lqmixm7s 39 15 enzyme enzyme NN cord-282256-lqmixm7s 39 16 and and CC cord-282256-lqmixm7s 39 17 the the DT cord-282256-lqmixm7s 39 18 protective protective JJ cord-282256-lqmixm7s 39 19 actions action NNS cord-282256-lqmixm7s 39 20 of of IN cord-282256-lqmixm7s 39 21 the the DT cord-282256-lqmixm7s 39 22 latter latter JJ cord-282256-lqmixm7s 39 23 are be VBP cord-282256-lqmixm7s 39 24 significantly significantly RB cord-282256-lqmixm7s 39 25 attenuated attenuate VBN cord-282256-lqmixm7s 39 26 . . . cord-282256-lqmixm7s 40 1 The the DT cord-282256-lqmixm7s 40 2 non non JJ cord-282256-lqmixm7s 40 3 - - JJ cord-282256-lqmixm7s 40 4 counterbalanced counterbalanced JJ cord-282256-lqmixm7s 40 5 actions action NNS cord-282256-lqmixm7s 40 6 of of IN cord-282256-lqmixm7s 40 7 angiotensin angiotensin NN cord-282256-lqmixm7s 40 8 II II NNP cord-282256-lqmixm7s 40 9 are be VBP cord-282256-lqmixm7s 40 10 partially partially RB cord-282256-lqmixm7s 40 11 responsible responsible JJ cord-282256-lqmixm7s 40 12 along along IN cord-282256-lqmixm7s 40 13 with with IN cord-282256-lqmixm7s 40 14 inflammation inflammation NN cord-282256-lqmixm7s 40 15 and and CC cord-282256-lqmixm7s 40 16 thrombotic thrombotic JJ cord-282256-lqmixm7s 40 17 milieu milieu NN cord-282256-lqmixm7s 40 18 to to IN cord-282256-lqmixm7s 40 19 the the DT cord-282256-lqmixm7s 40 20 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 40 21 related related JJ cord-282256-lqmixm7s 40 22 severe severe JJ cord-282256-lqmixm7s 40 23 complications complication NNS cord-282256-lqmixm7s 40 24 . . . cord-282256-lqmixm7s 41 1 At at IN cord-282256-lqmixm7s 41 2 the the DT cord-282256-lqmixm7s 41 3 level level NN cord-282256-lqmixm7s 41 4 of of IN cord-282256-lqmixm7s 41 5 the the DT cord-282256-lqmixm7s 41 6 lungs lung NNS cord-282256-lqmixm7s 41 7 the the DT cord-282256-lqmixm7s 41 8 virus virus NN cord-282256-lqmixm7s 41 9 reduces reduce VBZ cord-282256-lqmixm7s 41 10 the the DT cord-282256-lqmixm7s 41 11 activity activity NN cord-282256-lqmixm7s 41 12 of of IN cord-282256-lqmixm7s 41 13 the the DT cord-282256-lqmixm7s 41 14 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 41 15 and and CC cord-282256-lqmixm7s 41 16 regionally regionally RB cord-282256-lqmixm7s 41 17 stimulates stimulate VBZ cord-282256-lqmixm7s 41 18 the the DT cord-282256-lqmixm7s 41 19 renin renin NN cord-282256-lqmixm7s 41 20 - - HYPH cord-282256-lqmixm7s 41 21 angiotensin angiotensin NN cord-282256-lqmixm7s 41 22 system system NN cord-282256-lqmixm7s 41 23 with with IN cord-282256-lqmixm7s 41 24 leucocytes leucocytes NNP cord-282256-lqmixm7s 41 25 infiltration infiltration NN cord-282256-lqmixm7s 41 26 facilitation facilitation NN cord-282256-lqmixm7s 41 27 further further RB cord-282256-lqmixm7s 41 28 accelerating accelerate VBG cord-282256-lqmixm7s 41 29 the the DT cord-282256-lqmixm7s 41 30 progression progression NN cord-282256-lqmixm7s 41 31 of of IN cord-282256-lqmixm7s 41 32 the the DT cord-282256-lqmixm7s 41 33 inflammatory inflammatory JJ cord-282256-lqmixm7s 41 34 response response NN cord-282256-lqmixm7s 41 35 . . . cord-282256-lqmixm7s 42 1 In in IN cord-282256-lqmixm7s 42 2 a a DT cord-282256-lqmixm7s 42 3 relative relative JJ cord-282256-lqmixm7s 42 4 study study NN cord-282256-lqmixm7s 42 5 , , , cord-282256-lqmixm7s 42 6 COVID-19 covid-19 JJ cord-282256-lqmixm7s 42 7 patients patient NNS cord-282256-lqmixm7s 42 8 were be VBD cord-282256-lqmixm7s 42 9 characterized characterize VBN cord-282256-lqmixm7s 42 10 by by IN cord-282256-lqmixm7s 42 11 higher high JJR cord-282256-lqmixm7s 42 12 angiotensin angiotensin NN cord-282256-lqmixm7s 42 13 II ii CD cord-282256-lqmixm7s 42 14 levels level NNS cord-282256-lqmixm7s 42 15 that that WDT cord-282256-lqmixm7s 42 16 were be VBD cord-282256-lqmixm7s 42 17 closely closely RB cord-282256-lqmixm7s 42 18 related relate VBN cord-282256-lqmixm7s 42 19 to to IN cord-282256-lqmixm7s 42 20 the the DT cord-282256-lqmixm7s 42 21 total total JJ cord-282256-lqmixm7s 42 22 viral viral JJ cord-282256-lqmixm7s 42 23 load load NN cord-282256-lqmixm7s 42 24 and and CC cord-282256-lqmixm7s 42 25 the the DT cord-282256-lqmixm7s 42 26 degree degree NN cord-282256-lqmixm7s 42 27 of of IN cord-282256-lqmixm7s 42 28 lung lung NN cord-282256-lqmixm7s 42 29 injury injury NN cord-282256-lqmixm7s 42 30 . . . cord-282256-lqmixm7s 43 1 12 12 CD cord-282256-lqmixm7s 44 1 Recombinant Recombinant NNP cord-282256-lqmixm7s 44 2 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 44 3 administration administration NN cord-282256-lqmixm7s 44 4 has have VBZ cord-282256-lqmixm7s 44 5 been be VBN cord-282256-lqmixm7s 44 6 proposed propose VBN cord-282256-lqmixm7s 44 7 as as IN cord-282256-lqmixm7s 44 8 a a DT cord-282256-lqmixm7s 44 9 means means NN cord-282256-lqmixm7s 44 10 to to TO cord-282256-lqmixm7s 44 11 reduce reduce VB cord-282256-lqmixm7s 44 12 angiotensin angiotensin NN cord-282256-lqmixm7s 44 13 II ii CD cord-282256-lqmixm7s 44 14 levels level NNS cord-282256-lqmixm7s 44 15 and and CC cord-282256-lqmixm7s 44 16 lung lung NN cord-282256-lqmixm7s 44 17 tissue tissue NN cord-282256-lqmixm7s 44 18 lesions lesion NNS cord-282256-lqmixm7s 44 19 . . . cord-282256-lqmixm7s 45 1 10 10 CD cord-282256-lqmixm7s 45 2 , , , cord-282256-lqmixm7s 45 3 11 11 CD cord-282256-lqmixm7s 46 1 Concerning concern VBG cord-282256-lqmixm7s 46 2 the the DT cord-282256-lqmixm7s 46 3 heart heart NN cord-282256-lqmixm7s 46 4 and and CC cord-282256-lqmixm7s 46 5 vascular vascular JJ cord-282256-lqmixm7s 46 6 component component NN cord-282256-lqmixm7s 46 7 of of IN cord-282256-lqmixm7s 46 8 COVID-19 covid-19 JJ cord-282256-lqmixm7s 46 9 infection infection NN cord-282256-lqmixm7s 46 10 , , , cord-282256-lqmixm7s 46 11 dysregulation dysregulation NN cord-282256-lqmixm7s 46 12 of of IN cord-282256-lqmixm7s 46 13 the the DT cord-282256-lqmixm7s 46 14 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 46 15 related related JJ cord-282256-lqmixm7s 46 16 pathways pathway NNS cord-282256-lqmixm7s 46 17 are be VBP cord-282256-lqmixm7s 46 18 linked link VBN cord-282256-lqmixm7s 46 19 to to IN cord-282256-lqmixm7s 46 20 cardiac cardiac JJ cord-282256-lqmixm7s 46 21 muscle muscle NN cord-282256-lqmixm7s 46 22 injury injury NN cord-282256-lqmixm7s 46 23 and and CC cord-282256-lqmixm7s 46 24 potential potential JJ cord-282256-lqmixm7s 46 25 hemodynamic hemodynamic JJ cord-282256-lqmixm7s 46 26 collapse collapse NN cord-282256-lqmixm7s 46 27 . . . cord-282256-lqmixm7s 47 1 10 10 CD cord-282256-lqmixm7s 47 2 , , , cord-282256-lqmixm7s 47 3 11 11 CD cord-282256-lqmixm7s 48 1 Given give VBN cord-282256-lqmixm7s 48 2 consideration consideration NN cord-282256-lqmixm7s 48 3 of of IN cord-282256-lqmixm7s 48 4 the the DT cord-282256-lqmixm7s 48 5 above above JJ cord-282256-lqmixm7s 48 6 , , , cord-282256-lqmixm7s 48 7 the the DT cord-282256-lqmixm7s 48 8 " " `` cord-282256-lqmixm7s 48 9 million million CD cord-282256-lqmixm7s 48 10 dollars dollar NNS cord-282256-lqmixm7s 48 11 question question NN cord-282256-lqmixm7s 48 12 " " '' cord-282256-lqmixm7s 48 13 , , , cord-282256-lqmixm7s 48 14 is be VBZ cord-282256-lqmixm7s 48 15 about about IN cord-282256-lqmixm7s 48 16 the the DT cord-282256-lqmixm7s 48 17 effects effect NNS cord-282256-lqmixm7s 48 18 of of IN cord-282256-lqmixm7s 48 19 renin renin NN cord-282256-lqmixm7s 48 20 angiotensin angiotensin NN cord-282256-lqmixm7s 48 21 blockers blocker NNS cord-282256-lqmixm7s 48 22 on on IN cord-282256-lqmixm7s 48 23 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 48 24 expression expression NN cord-282256-lqmixm7s 48 25 / / SYM cord-282256-lqmixm7s 48 26 action action NN cord-282256-lqmixm7s 48 27 and and CC cord-282256-lqmixm7s 48 28 most most RBS cord-282256-lqmixm7s 48 29 importantly importantly RB cord-282256-lqmixm7s 48 30 what what WP cord-282256-lqmixm7s 48 31 is be VBZ cord-282256-lqmixm7s 48 32 the the DT cord-282256-lqmixm7s 48 33 clinical clinical JJ cord-282256-lqmixm7s 48 34 relevance relevance NN cord-282256-lqmixm7s 48 35 of of IN cord-282256-lqmixm7s 48 36 this this DT cord-282256-lqmixm7s 48 37 modulation modulation NN cord-282256-lqmixm7s 48 38 in in IN cord-282256-lqmixm7s 48 39 humans human NNS cord-282256-lqmixm7s 48 40 in in IN cord-282256-lqmixm7s 48 41 the the DT cord-282256-lqmixm7s 48 42 context context NN cord-282256-lqmixm7s 48 43 of of IN cord-282256-lqmixm7s 48 44 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 48 45 . . . cord-282256-lqmixm7s 49 1 There there EX cord-282256-lqmixm7s 49 2 are be VBP cord-282256-lqmixm7s 49 3 data datum NNS cord-282256-lqmixm7s 49 4 from from IN cord-282256-lqmixm7s 49 5 animal animal NN cord-282256-lqmixm7s 49 6 studies study NNS cord-282256-lqmixm7s 49 7 for for IN cord-282256-lqmixm7s 49 8 a a DT cord-282256-lqmixm7s 49 9 more more RBR cord-282256-lqmixm7s 49 10 consistent consistent JJ cord-282256-lqmixm7s 49 11 upregulation upregulation NN cord-282256-lqmixm7s 49 12 of of IN cord-282256-lqmixm7s 49 13 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 49 14 with with IN cord-282256-lqmixm7s 49 15 the the DT cord-282256-lqmixm7s 49 16 majority majority NN cord-282256-lqmixm7s 49 17 of of IN cord-282256-lqmixm7s 49 18 ARBs arb NNS cord-282256-lqmixm7s 49 19 , , , cord-282256-lqmixm7s 49 20 while while IN cord-282256-lqmixm7s 49 21 the the DT cord-282256-lqmixm7s 49 22 effect effect NN cord-282256-lqmixm7s 49 23 of of IN cord-282256-lqmixm7s 49 24 ACEIs acei NNS cord-282256-lqmixm7s 49 25 was be VBD cord-282256-lqmixm7s 49 26 variable variable JJ cord-282256-lqmixm7s 49 27 . . . cord-282256-lqmixm7s 50 1 7 7 CD cord-282256-lqmixm7s 51 1 This this DT cord-282256-lqmixm7s 51 2 knowledge knowledge NN cord-282256-lqmixm7s 51 3 led lead VBD cord-282256-lqmixm7s 51 4 to to IN cord-282256-lqmixm7s 51 5 the the DT cord-282256-lqmixm7s 51 6 opinion opinion NN cord-282256-lqmixm7s 51 7 of of IN cord-282256-lqmixm7s 51 8 potential potential JJ cord-282256-lqmixm7s 51 9 susceptibility susceptibility NN cord-282256-lqmixm7s 51 10 of of IN cord-282256-lqmixm7s 51 11 patients patient NNS cord-282256-lqmixm7s 51 12 on on IN cord-282256-lqmixm7s 51 13 ACEIs acei NNS cord-282256-lqmixm7s 51 14 and and CC cord-282256-lqmixm7s 51 15 ARBs arb NNS cord-282256-lqmixm7s 51 16 to to TO cord-282256-lqmixm7s 51 17 COVID-19 covid-19 VB cord-282256-lqmixm7s 51 18 infection infection NN cord-282256-lqmixm7s 51 19 13 13 CD cord-282256-lqmixm7s 52 1 but but CC cord-282256-lqmixm7s 52 2 this this DT cord-282256-lqmixm7s 52 3 is be VBZ cord-282256-lqmixm7s 52 4 currently currently RB cord-282256-lqmixm7s 52 5 unjustified unjustified JJ cord-282256-lqmixm7s 52 6 . . . cord-282256-lqmixm7s 53 1 Firstly firstly RB cord-282256-lqmixm7s 53 2 , , , cord-282256-lqmixm7s 53 3 the the DT cord-282256-lqmixm7s 53 4 data datum NNS cord-282256-lqmixm7s 53 5 in in IN cord-282256-lqmixm7s 53 6 humans human NNS cord-282256-lqmixm7s 53 7 are be VBP cord-282256-lqmixm7s 53 8 scarce scarce JJ cord-282256-lqmixm7s 53 9 and and CC cord-282256-lqmixm7s 53 10 only only RB cord-282256-lqmixm7s 53 11 in in IN cord-282256-lqmixm7s 53 12 the the DT cord-282256-lqmixm7s 53 13 small small JJ cord-282256-lqmixm7s 53 14 intestine intestine NN cord-282256-lqmixm7s 53 15 enterocytes enterocyte NNS cord-282256-lqmixm7s 53 16 upregulation upregulation NN cord-282256-lqmixm7s 53 17 of of IN cord-282256-lqmixm7s 53 18 ACE-2 ACE-2 NNP cord-282256-lqmixm7s 53 19 is be VBZ cord-282256-lqmixm7s 53 20 reported report VBN cord-282256-lqmixm7s 53 21 due due IN cord-282256-lqmixm7s 53 22 to to IN cord-282256-lqmixm7s 53 23 ACEI ACEI NNP cord-282256-lqmixm7s 53 24 . . . cord-282256-lqmixm7s 54 1 14 14 CD cord-282256-lqmixm7s 55 1 Regarding regard VBG cord-282256-lqmixm7s 55 2 the the DT cord-282256-lqmixm7s 55 3 lungs lung NNS cord-282256-lqmixm7s 55 4 there there EX cord-282256-lqmixm7s 55 5 are be VBP cord-282256-lqmixm7s 55 6 zero zero CD cord-282256-lqmixm7s 55 7 evidence evidence NN cord-282256-lqmixm7s 55 8 for for IN cord-282256-lqmixm7s 55 9 humans human NNS cord-282256-lqmixm7s 55 10 and and CC cord-282256-lqmixm7s 55 11 even even RB cord-282256-lqmixm7s 55 12 if if IN cord-282256-lqmixm7s 55 13 existed exist VBN cord-282256-lqmixm7s 55 14 can can MD cord-282256-lqmixm7s 55 15 not not RB cord-282256-lqmixm7s 55 16 directly directly RB cord-282256-lqmixm7s 55 17 lead lead VB cord-282256-lqmixm7s 55 18 to to IN cord-282256-lqmixm7s 55 19 the the DT cord-282256-lqmixm7s 55 20 conclusion conclusion NN cord-282256-lqmixm7s 55 21 that that IN cord-282256-lqmixm7s 55 22 this this DT cord-282256-lqmixm7s 55 23 upregulation upregulation NN cord-282256-lqmixm7s 55 24 can can MD cord-282256-lqmixm7s 55 25 indeed indeed RB cord-282256-lqmixm7s 55 26 facilitate facilitate VB cord-282256-lqmixm7s 55 27 viral viral JJ cord-282256-lqmixm7s 55 28 cell cell NN cord-282256-lqmixm7s 55 29 entry entry NN cord-282256-lqmixm7s 55 30 . . . cord-282256-lqmixm7s 56 1 7 7 CD cord-282256-lqmixm7s 57 1 If if IN cord-282256-lqmixm7s 57 2 one one PRP cord-282256-lqmixm7s 57 3 wants want VBZ cord-282256-lqmixm7s 57 4 to to TO cord-282256-lqmixm7s 57 5 focus focus VB cord-282256-lqmixm7s 57 6 on on IN cord-282256-lqmixm7s 57 7 pneumonia pneumonia NN cord-282256-lqmixm7s 57 8 outside outside IN cord-282256-lqmixm7s 57 9 the the DT cord-282256-lqmixm7s 57 10 COVID-19 covid-19 NN cord-282256-lqmixm7s 57 11 setting setting NN cord-282256-lqmixm7s 57 12 , , , cord-282256-lqmixm7s 57 13 the the DT cord-282256-lqmixm7s 57 14 use use NN cord-282256-lqmixm7s 57 15 of of IN cord-282256-lqmixm7s 57 16 ACEIs acei NNS cord-282256-lqmixm7s 57 17 and and CC cord-282256-lqmixm7s 57 18 ARBs arb NNS cord-282256-lqmixm7s 57 19 reduces reduce VBZ cord-282256-lqmixm7s 57 20 the the DT cord-282256-lqmixm7s 57 21 risk risk NN cord-282256-lqmixm7s 57 22 of of IN cord-282256-lqmixm7s 57 23 infection infection NN cord-282256-lqmixm7s 57 24 15 15 CD cord-282256-lqmixm7s 57 25 and and CC cord-282256-lqmixm7s 57 26 related related JJ cord-282256-lqmixm7s 57 27 mortality mortality NN cord-282256-lqmixm7s 57 28 . . . cord-282256-lqmixm7s 58 1 7 7 CD cord-282256-lqmixm7s 59 1 In in IN cord-282256-lqmixm7s 59 2 the the DT cord-282256-lqmixm7s 59 3 era era NN cord-282256-lqmixm7s 59 4 of of IN cord-282256-lqmixm7s 59 5 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 59 6 " " `` cord-282256-lqmixm7s 59 7 social social JJ cord-282256-lqmixm7s 59 8 distancing distancing NN cord-282256-lqmixm7s 59 9 " " '' cord-282256-lqmixm7s 59 10 , , , cord-282256-lqmixm7s 59 11 the the DT cord-282256-lqmixm7s 59 12 " " `` cord-282256-lqmixm7s 59 13 scientific scientific JJ cord-282256-lqmixm7s 59 14 approaching approaching NN cord-282256-lqmixm7s 59 15 " " '' cord-282256-lqmixm7s 59 16 by by IN cord-282256-lqmixm7s 59 17 rapid rapid JJ cord-282256-lqmixm7s 59 18 and and CC cord-282256-lqmixm7s 59 19 free free JJ cord-282256-lqmixm7s 59 20 exchange exchange NN cord-282256-lqmixm7s 59 21 of of IN cord-282256-lqmixm7s 59 22 knowledge knowledge NN cord-282256-lqmixm7s 59 23 provides provide VBZ cord-282256-lqmixm7s 59 24 the the DT cord-282256-lqmixm7s 59 25 scaffold scaffold NN cord-282256-lqmixm7s 59 26 for for IN cord-282256-lqmixm7s 59 27 better well JJR cord-282256-lqmixm7s 59 28 therapeutic therapeutic JJ cord-282256-lqmixm7s 59 29 answers answer NNS cord-282256-lqmixm7s 59 30 . . . cord-282256-lqmixm7s 60 1 We -PRON- PRP cord-282256-lqmixm7s 60 2 should should MD cord-282256-lqmixm7s 60 3 be be VB cord-282256-lqmixm7s 60 4 therefore therefore RB cord-282256-lqmixm7s 60 5 thankful thankful JJ cord-282256-lqmixm7s 60 6 to to IN cord-282256-lqmixm7s 60 7 the the DT cord-282256-lqmixm7s 60 8 researchers researcher NNS cord-282256-lqmixm7s 60 9 for for IN cord-282256-lqmixm7s 60 10 the the DT cord-282256-lqmixm7s 60 11 important important JJ cord-282256-lqmixm7s 60 12 emerging emerge VBG cord-282256-lqmixm7s 60 13 data datum NNS cord-282256-lqmixm7s 60 14 . . . cord-282256-lqmixm7s 61 1 [ [ -LRB- cord-282256-lqmixm7s 61 2 16 16 CD cord-282256-lqmixm7s 61 3 ] ] -RRB- cord-282256-lqmixm7s 61 4 [ [ -LRB- cord-282256-lqmixm7s 61 5 17 17 CD cord-282256-lqmixm7s 61 6 ] ] -RRB- cord-282256-lqmixm7s 61 7 [ [ -LRB- cord-282256-lqmixm7s 61 8 18 18 CD cord-282256-lqmixm7s 61 9 ] ] -RRB- cord-282256-lqmixm7s 61 10 [ [ -LRB- cord-282256-lqmixm7s 61 11 19 19 CD cord-282256-lqmixm7s 61 12 ] ] -RRB- cord-282256-lqmixm7s 62 1 Firstly firstly RB cord-282256-lqmixm7s 62 2 , , , cord-282256-lqmixm7s 62 3 Zhang Zhang NNP cord-282256-lqmixm7s 62 4 P P NNP cord-282256-lqmixm7s 62 5 et et NNP cord-282256-lqmixm7s 62 6 al al NNP cord-282256-lqmixm7s 62 7 conducted conduct VBD cord-282256-lqmixm7s 62 8 a a DT cord-282256-lqmixm7s 62 9 retrospective retrospective JJ cord-282256-lqmixm7s 62 10 , , , cord-282256-lqmixm7s 62 11 multicenter multicenter JJ cord-282256-lqmixm7s 62 12 study study NN cord-282256-lqmixm7s 62 13 including include VBG cord-282256-lqmixm7s 62 14 1128 1128 CD cord-282256-lqmixm7s 62 15 adult adult NN cord-282256-lqmixm7s 62 16 patients patient NNS cord-282256-lqmixm7s 62 17 with with IN cord-282256-lqmixm7s 62 18 hypertension hypertension NN cord-282256-lqmixm7s 62 19 diagnosed diagnose VBN cord-282256-lqmixm7s 62 20 with with IN cord-282256-lqmixm7s 62 21 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 62 22 and and CC cord-282256-lqmixm7s 62 23 admitted admit VBN cord-282256-lqmixm7s 62 24 to to IN cord-282256-lqmixm7s 62 25 hospitals hospital NNS cord-282256-lqmixm7s 62 26 in in IN cord-282256-lqmixm7s 62 27 the the DT cord-282256-lqmixm7s 62 28 Hubei Hubei NNP cord-282256-lqmixm7s 62 29 Province Province NNP cord-282256-lqmixm7s 62 30 . . . cord-282256-lqmixm7s 63 1 16 16 CD cord-282256-lqmixm7s 64 1 They -PRON- PRP cord-282256-lqmixm7s 64 2 showed show VBD cord-282256-lqmixm7s 64 3 that that IN cord-282256-lqmixm7s 64 4 the the DT cord-282256-lqmixm7s 64 5 incidence incidence NN cord-282256-lqmixm7s 64 6 of of IN cord-282256-lqmixm7s 64 7 the the DT cord-282256-lqmixm7s 64 8 28-day 28-day CD cord-282256-lqmixm7s 64 9 all all DT cord-282256-lqmixm7s 64 10 - - HYPH cord-282256-lqmixm7s 64 11 cause cause NN cord-282256-lqmixm7s 64 12 death death NN cord-282256-lqmixm7s 64 13 among among IN cord-282256-lqmixm7s 64 14 hypertensives hypertensives NNP cord-282256-lqmixm7s 64 15 who who WP cord-282256-lqmixm7s 64 16 had have VBD cord-282256-lqmixm7s 64 17 inpatient inpatient JJ cord-282256-lqmixm7s 64 18 treatment treatment NN cord-282256-lqmixm7s 64 19 with with IN cord-282256-lqmixm7s 64 20 ACEIs acei NNS cord-282256-lqmixm7s 64 21 / / SYM cord-282256-lqmixm7s 64 22 ARBs arb NNS cord-282256-lqmixm7s 64 23 is be VBZ cord-282256-lqmixm7s 64 24 significant significant JJ cord-282256-lqmixm7s 64 25 lower low JJR cord-282256-lqmixm7s 64 26 compared compare VBN cord-282256-lqmixm7s 64 27 with with IN cord-282256-lqmixm7s 64 28 ACEI ACEI NNP cord-282256-lqmixm7s 64 29 / / SYM cord-282256-lqmixm7s 64 30 ARB ARB NNP cord-282256-lqmixm7s 64 31 non non NNS cord-282256-lqmixm7s 64 32 - - NNS cord-282256-lqmixm7s 64 33 users user NNS cord-282256-lqmixm7s 64 34 ( ( -LRB- cord-282256-lqmixm7s 64 35 3.7 3.7 CD cord-282256-lqmixm7s 64 36 % % NN cord-282256-lqmixm7s 64 37 vs. vs. IN cord-282256-lqmixm7s 64 38 9.8 9.8 CD cord-282256-lqmixm7s 64 39 % % NN cord-282256-lqmixm7s 64 40 ; ; : cord-282256-lqmixm7s 64 41 p p NN cord-282256-lqmixm7s 64 42 = = SYM cord-282256-lqmixm7s 64 43 0.01 0.01 CD cord-282256-lqmixm7s 64 44 ) ) -RRB- cord-282256-lqmixm7s 64 45 . . . cord-282256-lqmixm7s 65 1 16 16 CD cord-282256-lqmixm7s 65 2 Even even RB cord-282256-lqmixm7s 65 3 after after IN cord-282256-lqmixm7s 65 4 matching match VBG cord-282256-lqmixm7s 65 5 and and CC cord-282256-lqmixm7s 65 6 adjusting adjust VBG cord-282256-lqmixm7s 65 7 variables variable NNS cord-282256-lqmixm7s 65 8 in in IN cord-282256-lqmixm7s 65 9 - - HYPH cord-282256-lqmixm7s 65 10 hospital hospital NN cord-282256-lqmixm7s 65 11 use use NN cord-282256-lqmixm7s 65 12 of of IN cord-282256-lqmixm7s 65 13 ACEIs acei NNS cord-282256-lqmixm7s 65 14 / / SYM cord-282256-lqmixm7s 65 15 ARBs arb NNS cord-282256-lqmixm7s 65 16 still still RB cord-282256-lqmixm7s 65 17 exhibits exhibit VBZ cord-282256-lqmixm7s 65 18 remarkable remarkable JJ cord-282256-lqmixm7s 65 19 association association NN cord-282256-lqmixm7s 65 20 with with IN cord-282256-lqmixm7s 65 21 reduced reduce VBN cord-282256-lqmixm7s 65 22 all all DT cord-282256-lqmixm7s 65 23 - - HYPH cord-282256-lqmixm7s 65 24 cause cause NN cord-282256-lqmixm7s 65 25 mortality mortality NN cord-282256-lqmixm7s 65 26 . . . cord-282256-lqmixm7s 66 1 And and CC cord-282256-lqmixm7s 66 2 even even RB cord-282256-lqmixm7s 66 3 more more RBR cord-282256-lqmixm7s 66 4 recently recently RB cord-282256-lqmixm7s 66 5 , , , cord-282256-lqmixm7s 66 6 three three CD cord-282256-lqmixm7s 66 7 simultaneous simultaneous JJ cord-282256-lqmixm7s 66 8 publications publication NNS cord-282256-lqmixm7s 66 9 shed shed VBP cord-282256-lqmixm7s 66 10 further further JJ cord-282256-lqmixm7s 66 11 light light NN cord-282256-lqmixm7s 66 12 into into IN cord-282256-lqmixm7s 66 13 the the DT cord-282256-lqmixm7s 66 14 debate debate NN cord-282256-lqmixm7s 66 15 of of IN cord-282256-lqmixm7s 66 16 renin renin NN cord-282256-lqmixm7s 66 17 - - HYPH cord-282256-lqmixm7s 66 18 angiotensin angiotensin NN cord-282256-lqmixm7s 66 19 therapies therapy NNS cord-282256-lqmixm7s 66 20 in in IN cord-282256-lqmixm7s 66 21 the the DT cord-282256-lqmixm7s 66 22 COVID-19 covid-19 JJ cord-282256-lqmixm7s 66 23 setting setting NN cord-282256-lqmixm7s 66 24 . . . cord-282256-lqmixm7s 67 1 [ [ -LRB- cord-282256-lqmixm7s 67 2 17 17 CD cord-282256-lqmixm7s 67 3 ] ] -RRB- cord-282256-lqmixm7s 67 4 [ [ -LRB- cord-282256-lqmixm7s 67 5 18 18 CD cord-282256-lqmixm7s 67 6 ] ] -RRB- cord-282256-lqmixm7s 67 7 [ [ -LRB- cord-282256-lqmixm7s 67 8 19 19 CD cord-282256-lqmixm7s 67 9 ] ] -RRB- cord-282256-lqmixm7s 68 1 The the DT cord-282256-lqmixm7s 68 2 work work NN cord-282256-lqmixm7s 68 3 by by IN cord-282256-lqmixm7s 68 4 Reynolds Reynolds NNP cord-282256-lqmixm7s 68 5 H H NNP cord-282256-lqmixm7s 68 6 et et NNP cord-282256-lqmixm7s 68 7 al al NNP cord-282256-lqmixm7s 68 8 showed show VBD cord-282256-lqmixm7s 68 9 that that IN cord-282256-lqmixm7s 68 10 among among IN cord-282256-lqmixm7s 68 11 12594 12594 CD cord-282256-lqmixm7s 68 12 patients patient NNS cord-282256-lqmixm7s 68 13 who who WP cord-282256-lqmixm7s 68 14 were be VBD cord-282256-lqmixm7s 68 15 tested test VBN cord-282256-lqmixm7s 68 16 for for IN cord-282256-lqmixm7s 68 17 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 68 18 there there EX cord-282256-lqmixm7s 68 19 was be VBD cord-282256-lqmixm7s 68 20 no no DT cord-282256-lqmixm7s 68 21 association association NN cord-282256-lqmixm7s 68 22 of of IN cord-282256-lqmixm7s 68 23 ACEIs acei NNS cord-282256-lqmixm7s 68 24 / / SYM cord-282256-lqmixm7s 68 25 ARBs arb NNS cord-282256-lqmixm7s 68 26 with with IN cord-282256-lqmixm7s 68 27 increased increase VBN cord-282256-lqmixm7s 68 28 likelihood likelihood NN cord-282256-lqmixm7s 68 29 of of IN cord-282256-lqmixm7s 68 30 a a DT cord-282256-lqmixm7s 68 31 positive positive JJ cord-282256-lqmixm7s 68 32 test test NN cord-282256-lqmixm7s 68 33 or or CC cord-282256-lqmixm7s 68 34 severe severe JJ cord-282256-lqmixm7s 68 35 infection infection NN cord-282256-lqmixm7s 68 36 . . . cord-282256-lqmixm7s 69 1 17 17 CD cord-282256-lqmixm7s 70 1 Further further JJ cord-282256-lqmixm7s 70 2 insight insight NN cord-282256-lqmixm7s 70 3 is be VBZ cord-282256-lqmixm7s 70 4 provided provide VBN cord-282256-lqmixm7s 70 5 by by IN cord-282256-lqmixm7s 70 6 Mancia Mancia NNP cord-282256-lqmixm7s 70 7 G G NNP cord-282256-lqmixm7s 70 8 et et FW cord-282256-lqmixm7s 70 9 al al NNP cord-282256-lqmixm7s 70 10 focusing focus VBG cord-282256-lqmixm7s 70 11 in in IN cord-282256-lqmixm7s 70 12 6272 6272 CD cord-282256-lqmixm7s 70 13 cases case NNS cord-282256-lqmixm7s 70 14 with with IN cord-282256-lqmixm7s 70 15 severe severe JJ cord-282256-lqmixm7s 70 16 COVID-19 covid-19 NN cord-282256-lqmixm7s 70 17 . . . cord-282256-lqmixm7s 71 1 18 18 CD cord-282256-lqmixm7s 72 1 After after IN cord-282256-lqmixm7s 72 2 adjustment adjustment NN cord-282256-lqmixm7s 72 3 for for IN cord-282256-lqmixm7s 72 4 confounders confounder NNS cord-282256-lqmixm7s 72 5 there there EX cord-282256-lqmixm7s 72 6 was be VBD cord-282256-lqmixm7s 72 7 no no DT cord-282256-lqmixm7s 72 8 independent independent JJ cord-282256-lqmixm7s 72 9 association association NN cord-282256-lqmixm7s 72 10 for for IN cord-282256-lqmixm7s 72 11 the the DT cord-282256-lqmixm7s 72 12 use use NN cord-282256-lqmixm7s 72 13 of of IN cord-282256-lqmixm7s 72 14 ACEIs acei NNS cord-282256-lqmixm7s 72 15 / / SYM cord-282256-lqmixm7s 72 16 ARBs arb NNS cord-282256-lqmixm7s 72 17 with with IN cord-282256-lqmixm7s 72 18 susceptibility susceptibility NN cord-282256-lqmixm7s 72 19 for for IN cord-282256-lqmixm7s 72 20 infection infection NN cord-282256-lqmixm7s 72 21 or or CC cord-282256-lqmixm7s 72 22 worse bad JJR cord-282256-lqmixm7s 72 23 clinical clinical JJ cord-282256-lqmixm7s 72 24 outcome outcome NN cord-282256-lqmixm7s 72 25 in in IN cord-282256-lqmixm7s 72 26 contrast contrast NN cord-282256-lqmixm7s 72 27 to to TO cord-282256-lqmixm7s 72 28 loop loop VB cord-282256-lqmixm7s 72 29 diuretics diuretic NNS cord-282256-lqmixm7s 72 30 that that WDT cord-282256-lqmixm7s 72 31 were be VBD cord-282256-lqmixm7s 72 32 linked link VBN cord-282256-lqmixm7s 72 33 to to IN cord-282256-lqmixm7s 72 34 enhanced enhance VBN cord-282256-lqmixm7s 72 35 risk risk NN cord-282256-lqmixm7s 72 36 . . . cord-282256-lqmixm7s 73 1 18 18 CD cord-282256-lqmixm7s 74 1 Interestingly interestingly RB cord-282256-lqmixm7s 74 2 the the DT cord-282256-lqmixm7s 74 3 publication publication NN cord-282256-lqmixm7s 74 4 by by IN cord-282256-lqmixm7s 74 5 Mehra Mehra NNP cord-282256-lqmixm7s 74 6 M M NNP cord-282256-lqmixm7s 74 7 et et NNP cord-282256-lqmixm7s 74 8 al al NNP cord-282256-lqmixm7s 74 9 , , , cord-282256-lqmixm7s 74 10 included include VBD cord-282256-lqmixm7s 74 11 international international JJ cord-282256-lqmixm7s 74 12 data datum NNS cord-282256-lqmixm7s 74 13 from from IN cord-282256-lqmixm7s 74 14 169 169 CD cord-282256-lqmixm7s 74 15 hospitals hospital NNS cord-282256-lqmixm7s 74 16 ( ( -LRB- cord-282256-lqmixm7s 74 17 11 11 CD cord-282256-lqmixm7s 74 18 countries country NNS cord-282256-lqmixm7s 74 19 in in IN cord-282256-lqmixm7s 74 20 Asia Asia NNP cord-282256-lqmixm7s 74 21 , , , cord-282256-lqmixm7s 74 22 Europe Europe NNP cord-282256-lqmixm7s 74 23 , , , cord-282256-lqmixm7s 74 24 and and CC cord-282256-lqmixm7s 74 25 North North NNP cord-282256-lqmixm7s 74 26 America America NNP cord-282256-lqmixm7s 74 27 ) ) -RRB- cord-282256-lqmixm7s 74 28 for for IN cord-282256-lqmixm7s 74 29 8910 8910 CD cord-282256-lqmixm7s 74 30 patients patient NNS cord-282256-lqmixm7s 74 31 with with IN cord-282256-lqmixm7s 74 32 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 74 33 for for IN cord-282256-lqmixm7s 74 34 whom whom WP cord-282256-lqmixm7s 74 35 discharge discharge NN cord-282256-lqmixm7s 74 36 status status NN cord-282256-lqmixm7s 74 37 was be VBD cord-282256-lqmixm7s 74 38 available available JJ cord-282256-lqmixm7s 74 39 . . . cord-282256-lqmixm7s 75 1 19 19 CD cord-282256-lqmixm7s 76 1 There there EX cord-282256-lqmixm7s 76 2 was be VBD cord-282256-lqmixm7s 76 3 no no DT cord-282256-lqmixm7s 76 4 harmful harmful JJ cord-282256-lqmixm7s 76 5 association association NN cord-282256-lqmixm7s 76 6 of of IN cord-282256-lqmixm7s 76 7 either either DT cord-282256-lqmixm7s 76 8 ACEIs acei NNS cord-282256-lqmixm7s 76 9 or or CC cord-282256-lqmixm7s 76 10 ARBs arb NNS cord-282256-lqmixm7s 76 11 with with IN cord-282256-lqmixm7s 76 12 mortality mortality NN cord-282256-lqmixm7s 76 13 but but CC cord-282256-lqmixm7s 76 14 also also RB cord-282256-lqmixm7s 76 15 it -PRON- PRP cord-282256-lqmixm7s 76 16 was be VBD cord-282256-lqmixm7s 76 17 demonstrated demonstrate VBN cord-282256-lqmixm7s 76 18 that that IN cord-282256-lqmixm7s 76 19 the the DT cord-282256-lqmixm7s 76 20 use use NN cord-282256-lqmixm7s 76 21 of of IN cord-282256-lqmixm7s 76 22 statins statin NNS cord-282256-lqmixm7s 76 23 and and CC cord-282256-lqmixm7s 76 24 ACEIs acei NNS cord-282256-lqmixm7s 76 25 was be VBD cord-282256-lqmixm7s 76 26 linked link VBN cord-282256-lqmixm7s 76 27 to to IN cord-282256-lqmixm7s 76 28 less less JJR cord-282256-lqmixm7s 76 29 in in IN cord-282256-lqmixm7s 76 30 - - HYPH cord-282256-lqmixm7s 76 31 hospital hospital NN cord-282256-lqmixm7s 76 32 deaths death NNS cord-282256-lqmixm7s 76 33 . . . cord-282256-lqmixm7s 77 1 19 19 CD cord-282256-lqmixm7s 78 1 These these DT cord-282256-lqmixm7s 78 2 findings finding NNS cord-282256-lqmixm7s 78 3 clearly clearly RB cord-282256-lqmixm7s 78 4 support support VBP cord-282256-lqmixm7s 78 5 recently recently RB cord-282256-lqmixm7s 78 6 published publish VBN cord-282256-lqmixm7s 78 7 recommendations recommendation NNS cord-282256-lqmixm7s 78 8 by by IN cord-282256-lqmixm7s 78 9 many many JJ cord-282256-lqmixm7s 78 10 societies society NNS cord-282256-lqmixm7s 78 11 regarding regard VBG cord-282256-lqmixm7s 78 12 continuation continuation NN cord-282256-lqmixm7s 78 13 of of IN cord-282256-lqmixm7s 78 14 ACEIs acei NNS cord-282256-lqmixm7s 78 15 or or CC cord-282256-lqmixm7s 78 16 ARBs arb NNS cord-282256-lqmixm7s 78 17 among among IN cord-282256-lqmixm7s 78 18 patients patient NNS cord-282256-lqmixm7s 78 19 with with IN cord-282256-lqmixm7s 78 20 co co JJ cord-282256-lqmixm7s 78 21 - - JJ cord-282256-lqmixm7s 78 22 existing existing JJ cord-282256-lqmixm7s 78 23 hypertension hypertension NN cord-282256-lqmixm7s 78 24 , , , cord-282256-lqmixm7s 78 25 cardiovascular cardiovascular JJ cord-282256-lqmixm7s 78 26 disease disease NN cord-282256-lqmixm7s 78 27 and and CC cord-282256-lqmixm7s 78 28 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 78 29 . . . cord-282256-lqmixm7s 79 1 20,21 20,21 CD cord-282256-lqmixm7s 80 1 Moreover moreover RB cord-282256-lqmixm7s 80 2 , , , cord-282256-lqmixm7s 80 3 they -PRON- PRP cord-282256-lqmixm7s 80 4 provide provide VBP cord-282256-lqmixm7s 80 5 further further JJ cord-282256-lqmixm7s 80 6 rationale rationale NN cord-282256-lqmixm7s 80 7 for for IN cord-282256-lqmixm7s 80 8 ongoing ongoing JJ cord-282256-lqmixm7s 80 9 studies study NNS cord-282256-lqmixm7s 80 10 with with IN cord-282256-lqmixm7s 80 11 drugs drug NNS cord-282256-lqmixm7s 80 12 targeting target VBG cord-282256-lqmixm7s 80 13 the the DT cord-282256-lqmixm7s 80 14 renin renin NN cord-282256-lqmixm7s 80 15 - - HYPH cord-282256-lqmixm7s 80 16 angiotensin angiotensin NN cord-282256-lqmixm7s 80 17 system system NN cord-282256-lqmixm7s 80 18 for for IN cord-282256-lqmixm7s 80 19 therapy therapy NN cord-282256-lqmixm7s 80 20 of of IN cord-282256-lqmixm7s 80 21 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 80 22 , , , cord-282256-lqmixm7s 80 23 like like IN cord-282256-lqmixm7s 80 24 losartan losartan NNP cord-282256-lqmixm7s 80 25 for for IN cord-282256-lqmixm7s 80 26 hospitalized hospitalize VBN cord-282256-lqmixm7s 80 27 ( ( -LRB- cord-282256-lqmixm7s 80 28 ΝCT04312009 νct04312009 CD cord-282256-lqmixm7s 80 29 ) ) -RRB- cord-282256-lqmixm7s 80 30 and and CC cord-282256-lqmixm7s 80 31 non non JJ cord-282256-lqmixm7s 80 32 - - JJ cord-282256-lqmixm7s 80 33 hospitalized hospitalize VBN cord-282256-lqmixm7s 80 34 patients patient NNS cord-282256-lqmixm7s 80 35 ( ( -LRB- cord-282256-lqmixm7s 80 36 NCT043111177 NCT043111177 NNP cord-282256-lqmixm7s 80 37 ) ) -RRB- cord-282256-lqmixm7s 80 38 . . . cord-282256-lqmixm7s 81 1 22 22 LS cord-282256-lqmixm7s 81 2 There there EX cord-282256-lqmixm7s 81 3 is be VBZ cord-282256-lqmixm7s 81 4 a a DT cord-282256-lqmixm7s 81 5 trending trending JJ cord-282256-lqmixm7s 81 6 notion notion NN cord-282256-lqmixm7s 81 7 that that IN cord-282256-lqmixm7s 81 8 there there EX cord-282256-lqmixm7s 81 9 is be VBZ cord-282256-lqmixm7s 81 10 not not RB cord-282256-lqmixm7s 81 11 only only RB cord-282256-lqmixm7s 81 12 a a DT cord-282256-lqmixm7s 81 13 " " `` cord-282256-lqmixm7s 81 14 second second JJ cord-282256-lqmixm7s 81 15 " " '' cord-282256-lqmixm7s 81 16 wave wave NN cord-282256-lqmixm7s 81 17 of of IN cord-282256-lqmixm7s 81 18 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 81 19 pandemic pandemic NN cord-282256-lqmixm7s 81 20 linked link VBN cord-282256-lqmixm7s 81 21 to to IN cord-282256-lqmixm7s 81 22 the the DT cord-282256-lqmixm7s 81 23 infection infection NN cord-282256-lqmixm7s 81 24 per per FW cord-282256-lqmixm7s 81 25 se se FW cord-282256-lqmixm7s 81 26 to to TO cord-282256-lqmixm7s 81 27 be be VB cord-282256-lqmixm7s 81 28 worried worry VBN cord-282256-lqmixm7s 81 29 about about IN cord-282256-lqmixm7s 81 30 but but CC cord-282256-lqmixm7s 81 31 also also RB cord-282256-lqmixm7s 81 32 a a DT cord-282256-lqmixm7s 81 33 " " `` cord-282256-lqmixm7s 81 34 third third JJ cord-282256-lqmixm7s 81 35 " " '' cord-282256-lqmixm7s 81 36 and and CC cord-282256-lqmixm7s 81 37 maybe maybe RB cord-282256-lqmixm7s 81 38 a a DT cord-282256-lqmixm7s 81 39 more more RBR cord-282256-lqmixm7s 81 40 important important JJ cord-282256-lqmixm7s 81 41 one one CD cord-282256-lqmixm7s 81 42 ! ! . cord-282256-lqmixm7s 82 1 This this DT cord-282256-lqmixm7s 82 2 " " `` cord-282256-lqmixm7s 82 3 third third JJ cord-282256-lqmixm7s 82 4 wave wave NN cord-282256-lqmixm7s 82 5 " " '' cord-282256-lqmixm7s 82 6 in in IN cord-282256-lqmixm7s 82 7 the the DT cord-282256-lqmixm7s 82 8 upcoming upcoming JJ cord-282256-lqmixm7s 82 9 months month NNS cord-282256-lqmixm7s 82 10 and and CC cord-282256-lqmixm7s 82 11 years year NNS cord-282256-lqmixm7s 82 12 is be VBZ cord-282256-lqmixm7s 82 13 related relate VBN cord-282256-lqmixm7s 82 14 to to IN cord-282256-lqmixm7s 82 15 major major JJ cord-282256-lqmixm7s 82 16 events event NNS cord-282256-lqmixm7s 82 17 that that WDT cord-282256-lqmixm7s 82 18 would would MD cord-282256-lqmixm7s 82 19 lead lead VB cord-282256-lqmixm7s 82 20 to to IN cord-282256-lqmixm7s 82 21 a a DT cord-282256-lqmixm7s 82 22 massive massive JJ cord-282256-lqmixm7s 82 23 burden burden NN cord-282256-lqmixm7s 82 24 to to IN cord-282256-lqmixm7s 82 25 the the DT cord-282256-lqmixm7s 82 26 health health NN cord-282256-lqmixm7s 82 27 systems system NNS cord-282256-lqmixm7s 82 28 because because IN cord-282256-lqmixm7s 82 29 of of IN cord-282256-lqmixm7s 82 30 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 82 31 related related JJ cord-282256-lqmixm7s 82 32 postponed postpone VBN cord-282256-lqmixm7s 82 33 guideline guideline NN cord-282256-lqmixm7s 82 34 care care NN cord-282256-lqmixm7s 82 35 in in IN cord-282256-lqmixm7s 82 36 major major JJ cord-282256-lqmixm7s 82 37 disease disease NN cord-282256-lqmixm7s 82 38 states state NNS cord-282256-lqmixm7s 82 39 among among IN cord-282256-lqmixm7s 82 40 them -PRON- PRP cord-282256-lqmixm7s 82 41 the the DT cord-282256-lqmixm7s 82 42 cardiovascular cardiovascular JJ cord-282256-lqmixm7s 82 43 ones one NNS cord-282256-lqmixm7s 82 44 . . . cord-282256-lqmixm7s 83 1 For for IN cord-282256-lqmixm7s 83 2 hypertensive hypertensive JJ cord-282256-lqmixm7s 83 3 patients patient NNS cord-282256-lqmixm7s 83 4 this this DT cord-282256-lqmixm7s 83 5 is be VBZ cord-282256-lqmixm7s 83 6 highly highly RB cord-282256-lqmixm7s 83 7 relevant relevant JJ cord-282256-lqmixm7s 83 8 due due IN cord-282256-lqmixm7s 83 9 to to IN cord-282256-lqmixm7s 83 10 the the DT cord-282256-lqmixm7s 83 11 lack lack NN cord-282256-lqmixm7s 83 12 of of IN cord-282256-lqmixm7s 83 13 regular regular JJ cord-282256-lqmixm7s 83 14 follow follow NN cord-282256-lqmixm7s 83 15 - - HYPH cord-282256-lqmixm7s 83 16 up up NN cord-282256-lqmixm7s 83 17 along along RB cord-282256-lqmixm7s 83 18 with with IN cord-282256-lqmixm7s 83 19 destabilization destabilization NN cord-282256-lqmixm7s 83 20 of of IN cord-282256-lqmixm7s 83 21 blood blood NN cord-282256-lqmixm7s 83 22 pressure pressure NN cord-282256-lqmixm7s 83 23 levels level NNS cord-282256-lqmixm7s 83 24 due due JJ cord-282256-lqmixm7s 83 25 to to IN cord-282256-lqmixm7s 83 26 unjustified unjustified JJ cord-282256-lqmixm7s 83 27 discontinuation discontinuation NN cord-282256-lqmixm7s 83 28 or or CC cord-282256-lqmixm7s 83 29 modification modification NN cord-282256-lqmixm7s 83 30 of of IN cord-282256-lqmixm7s 83 31 dosage dosage NN cord-282256-lqmixm7s 83 32 of of IN cord-282256-lqmixm7s 83 33 ACEIs acei NNS cord-282256-lqmixm7s 83 34 / / SYM cord-282256-lqmixm7s 83 35 ARBs arb NNS cord-282256-lqmixm7s 83 36 that that WDT cord-282256-lqmixm7s 83 37 can can MD cord-282256-lqmixm7s 83 38 lead lead VB cord-282256-lqmixm7s 83 39 to to IN cord-282256-lqmixm7s 83 40 heightened heighten VBN cord-282256-lqmixm7s 83 41 cardiovascular cardiovascular JJ cord-282256-lqmixm7s 83 42 risk risk NN cord-282256-lqmixm7s 83 43 . . . cord-282256-lqmixm7s 84 1 23 23 CD cord-282256-lqmixm7s 85 1 This this DT cord-282256-lqmixm7s 85 2 outsidethe outsidethe JJ cord-282256-lqmixm7s 85 3 - - HYPH cord-282256-lqmixm7s 85 4 norm norm NN cord-282256-lqmixm7s 85 5 approach approach NN cord-282256-lqmixm7s 85 6 to to IN cord-282256-lqmixm7s 85 7 chronic chronic JJ cord-282256-lqmixm7s 85 8 diseases disease NNS cord-282256-lqmixm7s 85 9 might may MD cord-282256-lqmixm7s 85 10 be be VB cord-282256-lqmixm7s 85 11 a a DT cord-282256-lqmixm7s 85 12 reaction reaction NN cord-282256-lqmixm7s 85 13 of of IN cord-282256-lqmixm7s 85 14 the the DT cord-282256-lqmixm7s 85 15 public public NN cord-282256-lqmixm7s 85 16 , , , cord-282256-lqmixm7s 85 17 as as RB cord-282256-lqmixm7s 85 18 well well RB cord-282256-lqmixm7s 85 19 as as IN cord-282256-lqmixm7s 85 20 of of IN cord-282256-lqmixm7s 85 21 some some DT cord-282256-lqmixm7s 85 22 health health NN cord-282256-lqmixm7s 85 23 providers provider NNS cord-282256-lqmixm7s 85 24 , , , cord-282256-lqmixm7s 85 25 to to IN cord-282256-lqmixm7s 85 26 the the DT cord-282256-lqmixm7s 85 27 media media NN cord-282256-lqmixm7s 85 28 - - HYPH cord-282256-lqmixm7s 85 29 induced induce VBN cord-282256-lqmixm7s 85 30 frenzy frenzy NN cord-282256-lqmixm7s 85 31 for for IN cord-282256-lqmixm7s 85 32 the the DT cord-282256-lqmixm7s 85 33 novel novel JJ cord-282256-lqmixm7s 85 34 coronavirus coronavirus NN cord-282256-lqmixm7s 85 35 . . . cord-282256-lqmixm7s 86 1 Attention attention NN cord-282256-lqmixm7s 86 2 should should MD cord-282256-lqmixm7s 86 3 be be VB cord-282256-lqmixm7s 86 4 paid pay VBN cord-282256-lqmixm7s 86 5 to to IN cord-282256-lqmixm7s 86 6 the the DT cord-282256-lqmixm7s 86 7 latter latter JJ cord-282256-lqmixm7s 86 8 phenomenon phenomenon NN cord-282256-lqmixm7s 86 9 and and CC cord-282256-lqmixm7s 86 10 the the DT cord-282256-lqmixm7s 86 11 cardiovascular cardiovascular JJ cord-282256-lqmixm7s 86 12 community community NN cord-282256-lqmixm7s 86 13 has have VBZ cord-282256-lqmixm7s 86 14 already already RB cord-282256-lqmixm7s 86 15 played play VBN cord-282256-lqmixm7s 86 16 a a DT cord-282256-lqmixm7s 86 17 key key JJ cord-282256-lqmixm7s 86 18 role role NN cord-282256-lqmixm7s 86 19 on on IN cord-282256-lqmixm7s 86 20 establishing establish VBG cord-282256-lqmixm7s 86 21 guidance guidance NN cord-282256-lqmixm7s 86 22 for for IN cord-282256-lqmixm7s 86 23 treatment treatment NN cord-282256-lqmixm7s 86 24 and and CC cord-282256-lqmixm7s 86 25 continuity continuity NN cord-282256-lqmixm7s 86 26 of of IN cord-282256-lqmixm7s 86 27 care care NN cord-282256-lqmixm7s 86 28 for for IN cord-282256-lqmixm7s 86 29 high high JJ cord-282256-lqmixm7s 86 30 risk risk NN cord-282256-lqmixm7s 86 31 patients patient NNS cord-282256-lqmixm7s 86 32 . . . cord-282256-lqmixm7s 87 1 7 7 CD cord-282256-lqmixm7s 87 2 , , , cord-282256-lqmixm7s 87 3 20 20 CD cord-282256-lqmixm7s 87 4 Interplay interplay NN cord-282256-lqmixm7s 87 5 with with IN cord-282256-lqmixm7s 87 6 the the DT cord-282256-lqmixm7s 87 7 organization organization NN cord-282256-lqmixm7s 87 8 of of IN cord-282256-lqmixm7s 87 9 the the DT cord-282256-lqmixm7s 87 10 health health NN cord-282256-lqmixm7s 87 11 systems system NNS cord-282256-lqmixm7s 87 12 and and CC cord-282256-lqmixm7s 87 13 governments government NNS cord-282256-lqmixm7s 87 14 is be VBZ cord-282256-lqmixm7s 87 15 needed need VBN cord-282256-lqmixm7s 87 16 to to TO cord-282256-lqmixm7s 87 17 sufficiently sufficiently RB cord-282256-lqmixm7s 87 18 address address VB cord-282256-lqmixm7s 87 19 the the DT cord-282256-lqmixm7s 87 20 " " `` cord-282256-lqmixm7s 87 21 burden burden NN cord-282256-lqmixm7s 87 22 " " '' cord-282256-lqmixm7s 87 23 of of IN cord-282256-lqmixm7s 87 24 cardiovascular cardiovascular JJ cord-282256-lqmixm7s 87 25 emergencies emergency NNS cord-282256-lqmixm7s 87 26 and and CC cord-282256-lqmixm7s 87 27 routine routine JJ cord-282256-lqmixm7s 87 28 cases case NNS cord-282256-lqmixm7s 87 29 throughout throughout IN cord-282256-lqmixm7s 87 30 the the DT cord-282256-lqmixm7s 87 31 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 87 32 era era NN cord-282256-lqmixm7s 87 33 . . . cord-282256-lqmixm7s 87 34 _SP cord-282256-lqmixm7s 88 1 Clinical clinical JJ cord-282256-lqmixm7s 88 2 course course NN cord-282256-lqmixm7s 88 3 and and CC cord-282256-lqmixm7s 88 4 risk risk NN cord-282256-lqmixm7s 88 5 factors factor NNS cord-282256-lqmixm7s 88 6 for for IN cord-282256-lqmixm7s 88 7 mortality mortality NN cord-282256-lqmixm7s 88 8 of of IN cord-282256-lqmixm7s 88 9 adult adult NN cord-282256-lqmixm7s 88 10 inpatients inpatient NNS cord-282256-lqmixm7s 88 11 with with IN cord-282256-lqmixm7s 88 12 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 88 13 in in IN cord-282256-lqmixm7s 88 14 Wuhan Wuhan NNP cord-282256-lqmixm7s 88 15 , , , cord-282256-lqmixm7s 88 16 China China NNP cord-282256-lqmixm7s 88 17 : : : cord-282256-lqmixm7s 88 18 a a DT cord-282256-lqmixm7s 88 19 retrospective retrospective JJ cord-282256-lqmixm7s 88 20 cohort cohort NN cord-282256-lqmixm7s 88 21 study study NN cord-282256-lqmixm7s 88 22 . . . cord-282256-lqmixm7s 89 1 The the DT cord-282256-lqmixm7s 89 2 Lancet Lancet NNP cord-282256-lqmixm7s 89 3 Clinical clinical JJ cord-282256-lqmixm7s 89 4 Characteristics characteristic NNS cord-282256-lqmixm7s 89 5 of of IN cord-282256-lqmixm7s 89 6 138 138 CD cord-282256-lqmixm7s 89 7 Hospitalized hospitalize VBN cord-282256-lqmixm7s 89 8 Patients patient NNS cord-282256-lqmixm7s 89 9 With with IN cord-282256-lqmixm7s 89 10 2019 2019 CD cord-282256-lqmixm7s 89 11 Novel Novel NNP cord-282256-lqmixm7s 89 12 Coronavirus Coronavirus NNP cord-282256-lqmixm7s 89 13 - - HYPH cord-282256-lqmixm7s 89 14 Infected infect VBN cord-282256-lqmixm7s 89 15 Pneumonia Pneumonia NNP cord-282256-lqmixm7s 89 16 in in IN cord-282256-lqmixm7s 89 17 Wuhan Wuhan NNP cord-282256-lqmixm7s 89 18 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 89 19 and and CC cord-282256-lqmixm7s 89 20 the the DT cord-282256-lqmixm7s 89 21 cardiovascular cardiovascular JJ cord-282256-lqmixm7s 89 22 system system NN cord-282256-lqmixm7s 89 23 Prevalence prevalence NN cord-282256-lqmixm7s 89 24 of of IN cord-282256-lqmixm7s 89 25 comorbidities comorbiditie NNS cord-282256-lqmixm7s 89 26 in in IN cord-282256-lqmixm7s 89 27 the the DT cord-282256-lqmixm7s 89 28 novel novel JJ cord-282256-lqmixm7s 89 29 Wuhan Wuhan NNP cord-282256-lqmixm7s 89 30 coronavirus coronavirus NN cord-282256-lqmixm7s 89 31 ( ( -LRB- cord-282256-lqmixm7s 89 32 COVID-19 covid-19 VB cord-282256-lqmixm7s 89 33 ) ) -RRB- cord-282256-lqmixm7s 89 34 infection infection NN cord-282256-lqmixm7s 89 35 : : : cord-282256-lqmixm7s 89 36 a a DT cord-282256-lqmixm7s 89 37 systematic systematic JJ cord-282256-lqmixm7s 89 38 review review NN cord-282256-lqmixm7s 89 39 and and CC cord-282256-lqmixm7s 89 40 meta meta NNP cord-282256-lqmixm7s 89 41 - - HYPH cord-282256-lqmixm7s 89 42 analysis analysis NN cord-282256-lqmixm7s 89 43 Hypertension hypertension NN cord-282256-lqmixm7s 89 44 , , , cord-282256-lqmixm7s 89 45 the the DT cord-282256-lqmixm7s 89 46 renin renin NN cord-282256-lqmixm7s 89 47 - - HYPH cord-282256-lqmixm7s 89 48 angiotensin angiotensin NN cord-282256-lqmixm7s 89 49 system system NN cord-282256-lqmixm7s 89 50 , , , cord-282256-lqmixm7s 89 51 and and CC cord-282256-lqmixm7s 89 52 the the DT cord-282256-lqmixm7s 89 53 risk risk NN cord-282256-lqmixm7s 89 54 of of IN cord-282256-lqmixm7s 89 55 lower low JJR cord-282256-lqmixm7s 89 56 respiratory respiratory JJ cord-282256-lqmixm7s 89 57 tract tract NN cord-282256-lqmixm7s 89 58 infections infection NNS cord-282256-lqmixm7s 89 59 and and CC cord-282256-lqmixm7s 89 60 lung lung NN cord-282256-lqmixm7s 89 61 injury injury NN cord-282256-lqmixm7s 89 62 : : : cord-282256-lqmixm7s 89 63 implications implication NNS cord-282256-lqmixm7s 89 64 for for IN cord-282256-lqmixm7s 89 65 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 89 66 Clinical clinical JJ cord-282256-lqmixm7s 89 67 features feature NNS cord-282256-lqmixm7s 89 68 of of IN cord-282256-lqmixm7s 89 69 patients patient NNS cord-282256-lqmixm7s 89 70 infected infect VBN cord-282256-lqmixm7s 89 71 with with IN cord-282256-lqmixm7s 89 72 2019 2019 CD cord-282256-lqmixm7s 89 73 novel novel JJ cord-282256-lqmixm7s 89 74 coronavirus coronavirus NN cord-282256-lqmixm7s 89 75 in in IN cord-282256-lqmixm7s 89 76 Wuhan Wuhan NNP cord-282256-lqmixm7s 89 77 , , , cord-282256-lqmixm7s 89 78 China China NNP cord-282256-lqmixm7s 89 79 Effects effect NNS cord-282256-lqmixm7s 89 80 of of IN cord-282256-lqmixm7s 89 81 oral oral JJ cord-282256-lqmixm7s 89 82 paricalcitol paricalcitol NN cord-282256-lqmixm7s 89 83 therapy therapy NN cord-282256-lqmixm7s 89 84 on on IN cord-282256-lqmixm7s 89 85 arterial arterial JJ cord-282256-lqmixm7s 89 86 stiffness stiffness NN cord-282256-lqmixm7s 89 87 and and CC cord-282256-lqmixm7s 89 88 osteopontin osteopontin NN cord-282256-lqmixm7s 89 89 in in IN cord-282256-lqmixm7s 89 90 hypertensive hypertensive JJ cord-282256-lqmixm7s 89 91 patients patient NNS cord-282256-lqmixm7s 89 92 with with IN cord-282256-lqmixm7s 89 93 chronic chronic JJ cord-282256-lqmixm7s 89 94 kidney kidney NN cord-282256-lqmixm7s 89 95 disease disease NN cord-282256-lqmixm7s 89 96 and and CC cord-282256-lqmixm7s 89 97 secondary secondary JJ cord-282256-lqmixm7s 89 98 hyperparathyroidism hyperparathyroidism NN cord-282256-lqmixm7s 89 99 Aldosterone Aldosterone NNP cord-282256-lqmixm7s 89 100 System System NNP cord-282256-lqmixm7s 89 101 Inhibitors Inhibitors NNP cord-282256-lqmixm7s 89 102 in in IN cord-282256-lqmixm7s 89 103 Patients patient NNS cord-282256-lqmixm7s 89 104 with with IN cord-282256-lqmixm7s 89 105 Covid-19 Covid-19 NNP cord-282256-lqmixm7s 89 106 Coronavirus Coronavirus NNP cord-282256-lqmixm7s 89 107 Disease Disease NNP cord-282256-lqmixm7s 89 108 2019 2019 CD cord-282256-lqmixm7s 89 109 ( ( -LRB- cord-282256-lqmixm7s 89 110 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 89 111 ) ) -RRB- cord-282256-lqmixm7s 89 112 and and CC cord-282256-lqmixm7s 89 113 Cardiovascular Cardiovascular NNP cord-282256-lqmixm7s 89 114 Disease Disease NNP cord-282256-lqmixm7s 89 115 : : : cord-282256-lqmixm7s 90 1 A a DT cord-282256-lqmixm7s 90 2 Viewpoint viewpoint NN cord-282256-lqmixm7s 90 3 on on IN cord-282256-lqmixm7s 90 4 the the DT cord-282256-lqmixm7s 90 5 Potential potential JJ cord-282256-lqmixm7s 90 6 Influence influence NN cord-282256-lqmixm7s 90 7 of of IN cord-282256-lqmixm7s 90 8 Angiotensin Angiotensin NNP cord-282256-lqmixm7s 90 9 - - HYPH cord-282256-lqmixm7s 90 10 Converting converting NN cord-282256-lqmixm7s 91 1 Enzyme Enzyme NNP cord-282256-lqmixm7s 91 2 Inhibitors Inhibitors NNP cord-282256-lqmixm7s 91 3 / / SYM cord-282256-lqmixm7s 91 4 Angiotensin Angiotensin NNP cord-282256-lqmixm7s 91 5 Receptor Receptor NNP cord-282256-lqmixm7s 91 6 Blockers Blockers NNP cord-282256-lqmixm7s 91 7 on on IN cord-282256-lqmixm7s 91 8 Onset Onset NNP cord-282256-lqmixm7s 91 9 and and CC cord-282256-lqmixm7s 91 10 Severity severity NN cord-282256-lqmixm7s 91 11 of of IN cord-282256-lqmixm7s 91 12 Severe severe JJ cord-282256-lqmixm7s 91 13 Acute acute JJ cord-282256-lqmixm7s 91 14 Respiratory Respiratory NNP cord-282256-lqmixm7s 91 15 Syndrome Syndrome NNP cord-282256-lqmixm7s 91 16 Coronavirus Coronavirus NNP cord-282256-lqmixm7s 91 17 2 2 CD cord-282256-lqmixm7s 91 18 Infection Infection NNP cord-282256-lqmixm7s 91 19 Clinical clinical JJ cord-282256-lqmixm7s 91 20 and and CC cord-282256-lqmixm7s 91 21 biochemical biochemical JJ cord-282256-lqmixm7s 91 22 indexes index NNS cord-282256-lqmixm7s 91 23 from from IN cord-282256-lqmixm7s 91 24 2019-nCoV 2019-ncov CD cord-282256-lqmixm7s 91 25 infected infect VBN cord-282256-lqmixm7s 91 26 patients patient NNS cord-282256-lqmixm7s 91 27 linked link VBN cord-282256-lqmixm7s 91 28 to to IN cord-282256-lqmixm7s 91 29 viral viral JJ cord-282256-lqmixm7s 91 30 loads load NNS cord-282256-lqmixm7s 91 31 and and CC cord-282256-lqmixm7s 91 32 lung lung NN cord-282256-lqmixm7s 91 33 injury injury NN cord-282256-lqmixm7s 92 1 Can Can MD cord-282256-lqmixm7s 92 2 angiotensin angiotensin NN cord-282256-lqmixm7s 92 3 receptor receptor NN cord-282256-lqmixm7s 92 4 - - HYPH cord-282256-lqmixm7s 92 5 blocking block VBG cord-282256-lqmixm7s 92 6 drugs drug NNS cord-282256-lqmixm7s 92 7 perhaps perhaps RB cord-282256-lqmixm7s 92 8 be be VB cord-282256-lqmixm7s 92 9 harmful harmful JJ cord-282256-lqmixm7s 92 10 in in IN cord-282256-lqmixm7s 92 11 the the DT cord-282256-lqmixm7s 92 12 COVID-19 covid-19 JJ cord-282256-lqmixm7s 92 13 pandemic pandemic NN cord-282256-lqmixm7s 92 14 ? ? . cord-282256-lqmixm7s 93 1 Urinary urinary JJ cord-282256-lqmixm7s 93 2 angiotensin angiotensin NN cord-282256-lqmixm7s 93 3 - - HYPH cord-282256-lqmixm7s 93 4 converting convert VBG cord-282256-lqmixm7s 93 5 enzyme enzyme NN cord-282256-lqmixm7s 93 6 2 2 CD cord-282256-lqmixm7s 93 7 in in IN cord-282256-lqmixm7s 93 8 hypertensive hypertensive JJ cord-282256-lqmixm7s 93 9 patients patient NNS cord-282256-lqmixm7s 93 10 may may MD cord-282256-lqmixm7s 93 11 be be VB cord-282256-lqmixm7s 93 12 increased increase VBN cord-282256-lqmixm7s 93 13 by by IN cord-282256-lqmixm7s 93 14 olmesartan olmesartan NNP cord-282256-lqmixm7s 93 15 , , , cord-282256-lqmixm7s 93 16 an an DT cord-282256-lqmixm7s 93 17 angiotensin angiotensin NN cord-282256-lqmixm7s 93 18 II ii CD cord-282256-lqmixm7s 93 19 receptor receptor NN cord-282256-lqmixm7s 93 20 blocker blocker NN cord-282256-lqmixm7s 93 21 Risk Risk NNP cord-282256-lqmixm7s 93 22 of of IN cord-282256-lqmixm7s 93 23 pneumonia pneumonia NN cord-282256-lqmixm7s 93 24 associated associate VBN cord-282256-lqmixm7s 93 25 with with IN cord-282256-lqmixm7s 93 26 use use NN cord-282256-lqmixm7s 93 27 of of IN cord-282256-lqmixm7s 93 28 angiotensin angiotensin NN cord-282256-lqmixm7s 93 29 converting convert VBG cord-282256-lqmixm7s 93 30 enzyme enzyme NN cord-282256-lqmixm7s 93 31 inhibitors inhibitor NNS cord-282256-lqmixm7s 93 32 and and CC cord-282256-lqmixm7s 93 33 angiotensin angiotensin NN cord-282256-lqmixm7s 93 34 receptor receptor NN cord-282256-lqmixm7s 93 35 blockers blocker NNS cord-282256-lqmixm7s 93 36 : : : cord-282256-lqmixm7s 93 37 systematic systematic JJ cord-282256-lqmixm7s 93 38 review review NN cord-282256-lqmixm7s 93 39 and and CC cord-282256-lqmixm7s 93 40 meta meta NNP cord-282256-lqmixm7s 93 41 - - HYPH cord-282256-lqmixm7s 93 42 analysis analysis NNP cord-282256-lqmixm7s 93 43 Association Association NNP cord-282256-lqmixm7s 93 44 of of IN cord-282256-lqmixm7s 93 45 Inpatient Inpatient NNP cord-282256-lqmixm7s 93 46 Use Use NNP cord-282256-lqmixm7s 93 47 of of IN cord-282256-lqmixm7s 93 48 Angiotensin Angiotensin NNP cord-282256-lqmixm7s 93 49 Converting Converting NNP cord-282256-lqmixm7s 93 50 Enzyme Enzyme NNP cord-282256-lqmixm7s 93 51 Inhibitors Inhibitors NNP cord-282256-lqmixm7s 93 52 and and CC cord-282256-lqmixm7s 93 53 Angiotensin Angiotensin NNP cord-282256-lqmixm7s 93 54 II II NNP cord-282256-lqmixm7s 93 55 Receptor Receptor NNP cord-282256-lqmixm7s 93 56 Blockers Blockers NNP cord-282256-lqmixm7s 93 57 with with IN cord-282256-lqmixm7s 93 58 Mortality mortality NN cord-282256-lqmixm7s 93 59 Among among IN cord-282256-lqmixm7s 93 60 Patients patient NNS cord-282256-lqmixm7s 93 61 With with IN cord-282256-lqmixm7s 93 62 Hypertension hypertension NN cord-282256-lqmixm7s 93 63 Hospitalized hospitalize VBN cord-282256-lqmixm7s 93 64 With with IN cord-282256-lqmixm7s 93 65 COVID-19 COVID-19 NNP cord-282256-lqmixm7s 93 66 Renin Renin NNP cord-282256-lqmixm7s 93 67 - - HYPH cord-282256-lqmixm7s 93 68 Angiotensin Angiotensin NNP cord-282256-lqmixm7s 93 69 - - HYPH cord-282256-lqmixm7s 93 70 Aldosterone Aldosterone NNP cord-282256-lqmixm7s 93 71 System System NNP cord-282256-lqmixm7s 93 72 Inhibitors Inhibitors NNP cord-282256-lqmixm7s 93 73 and and CC cord-282256-lqmixm7s 93 74 Risk Risk NNP cord-282256-lqmixm7s 93 75 of of IN cord-282256-lqmixm7s 93 76 Covid-19 Covid-19 NNP cord-282256-lqmixm7s 93 77 Renin Renin NNP cord-282256-lqmixm7s 93 78 - - HYPH cord-282256-lqmixm7s 93 79 Angiotensin Angiotensin NNP cord-282256-lqmixm7s 93 80 - - HYPH cord-282256-lqmixm7s 93 81 Aldosterone Aldosterone NNP cord-282256-lqmixm7s 93 82 System System NNP cord-282256-lqmixm7s 93 83 Blockers Blockers NNP cord-282256-lqmixm7s 93 84 and and CC cord-282256-lqmixm7s 93 85 the the DT cord-282256-lqmixm7s 93 86 Risk Risk NNP cord-282256-lqmixm7s 93 87 of of IN cord-282256-lqmixm7s 93 88 Covid-19 Covid-19 NNP cord-282256-lqmixm7s 93 89 Cardiovascular Cardiovascular NNP cord-282256-lqmixm7s 93 90 Disease Disease NNP cord-282256-lqmixm7s 93 91 , , , cord-282256-lqmixm7s 93 92 Drug Drug NNP cord-282256-lqmixm7s 93 93 Therapy Therapy NNP cord-282256-lqmixm7s 93 94 , , , cord-282256-lqmixm7s 93 95 and and CC cord-282256-lqmixm7s 93 96 Mortality mortality NN cord-282256-lqmixm7s 93 97 in in IN cord-282256-lqmixm7s 93 98 Covid-19 Covid-19 NNP cord-282256-lqmixm7s 93 99 The the DT cord-282256-lqmixm7s 93 100 new new JJ cord-282256-lqmixm7s 93 101 guidelines guideline NNS cord-282256-lqmixm7s 93 102 for for IN cord-282256-lqmixm7s 93 103 hypertension hypertension NN cord-282256-lqmixm7s 93 104 : : : cord-282256-lqmixm7s 93 105 Navigating navigate VBG cord-282256-lqmixm7s 93 106 between between IN cord-282256-lqmixm7s 93 107 Scylla Scylla NNP cord-282256-lqmixm7s 93 108 and and CC cord-282256-lqmixm7s 93 109 Charybdis Charybdis NNP cord-282256-lqmixm7s 93 110 of of IN cord-282256-lqmixm7s 93 111 clinical clinical JJ cord-282256-lqmixm7s 93 112 practice practice NN cord-282256-lqmixm7s 93 113 Controversies controversy NNS cord-282256-lqmixm7s 93 114 of of IN cord-282256-lqmixm7s 93 115 renin renin NN cord-282256-lqmixm7s 93 116 - - HYPH cord-282256-lqmixm7s 93 117 angiotensin angiotensin NN cord-282256-lqmixm7s 93 118 system system NN cord-282256-lqmixm7s 93 119 inhibition inhibition NN cord-282256-lqmixm7s 93 120 during during IN cord-282256-lqmixm7s 93 121 the the DT cord-282256-lqmixm7s 93 122 COVID-19 covid-19 CD cord-282256-lqmixm7s 93 123 pandemic pandemic NN cord-282256-lqmixm7s 93 124 Effects effect NNS cord-282256-lqmixm7s 93 125 of of IN cord-282256-lqmixm7s 93 126 blood blood NN cord-282256-lqmixm7s 93 127 pressure pressure NN cord-282256-lqmixm7s 93 128 lowering lower VBG cord-282256-lqmixm7s 93 129 treatment treatment NN cord-282256-lqmixm7s 93 130 in in IN cord-282256-lqmixm7s 93 131 hypertension hypertension NN cord-282256-lqmixm7s 93 132 : : : cord-282256-lqmixm7s 94 1 8 8 CD cord-282256-lqmixm7s 94 2 . . . cord-282256-lqmixm7s 95 1 Outcome outcome NN cord-282256-lqmixm7s 95 2 reductions reduction NNS cord-282256-lqmixm7s 95 3 vs. vs. IN cord-282256-lqmixm7s 95 4 discontinuations discontinuation NNS cord-282256-lqmixm7s 95 5 because because IN cord-282256-lqmixm7s 95 6 of of IN cord-282256-lqmixm7s 95 7 adverse adverse JJ cord-282256-lqmixm7s 95 8 drug drug NN cord-282256-lqmixm7s 95 9 events event NNS cord-282256-lqmixm7s 95 10 -meta -meta : cord-282256-lqmixm7s 95 11 - - HYPH cord-282256-lqmixm7s 95 12 analyses analysis NNS cord-282256-lqmixm7s 95 13 of of IN cord-282256-lqmixm7s 95 14 randomized randomized JJ cord-282256-lqmixm7s 95 15 trials trial NNS cord-282256-lqmixm7s 95 16 With with IN cord-282256-lqmixm7s 95 17 clinical clinical JJ cord-282256-lqmixm7s 95 18 strength strength NN cord-282256-lqmixm7s 95 19 , , , cord-282256-lqmixm7s 95 20 and and CC cord-282256-lqmixm7s 95 21 scientific scientific JJ cord-282256-lqmixm7s 95 22 rigor rigor NN cord-282256-lqmixm7s 95 23 , , , cord-282256-lqmixm7s 95 24 the the DT cord-282256-lqmixm7s 95 25 " " `` cord-282256-lqmixm7s 95 26 labyrinth labyrinth NN cord-282256-lqmixm7s 95 27 " " '' cord-282256-lqmixm7s 95 28 of of IN cord-282256-lqmixm7s 95 29 unanswered unanswered JJ cord-282256-lqmixm7s 95 30 questions question NNS cord-282256-lqmixm7s 95 31 will will MD cord-282256-lqmixm7s 95 32 be be VB cord-282256-lqmixm7s 95 33 solved solve VBN cord-282256-lqmixm7s 95 34 and and CC cord-282256-lqmixm7s 95 35 the the DT cord-282256-lqmixm7s 95 36 COVID-19 covid-19 JJ cord-282256-lqmixm7s 95 37 outbreak outbreak NN cord-282256-lqmixm7s 95 38 will will MD cord-282256-lqmixm7s 95 39 be be VB cord-282256-lqmixm7s 95 40 limited limit VBN cord-282256-lqmixm7s 95 41 . . . cord-282256-lqmixm7s 96 1 Concerning concern VBG cord-282256-lqmixm7s 96 2 hypertension hypertension NN cord-282256-lqmixm7s 96 3 therapy therapy NN cord-282256-lqmixm7s 96 4 , , , cord-282256-lqmixm7s 96 5 it -PRON- PRP cord-282256-lqmixm7s 96 6 seems seem VBZ cord-282256-lqmixm7s 96 7 at at IN cord-282256-lqmixm7s 96 8 present present JJ cord-282256-lqmixm7s 96 9 to to TO cord-282256-lqmixm7s 96 10 be be VB cord-282256-lqmixm7s 96 11 " " `` cord-282256-lqmixm7s 96 12 immune immune JJ cord-282256-lqmixm7s 96 13 " " '' cord-282256-lqmixm7s 96 14 to to IN cord-282256-lqmixm7s 96 15 COVID-19 covid-19 VB cord-282256-lqmixm7s 96 16 . . . cord-282256-lqmixm7s 97 1 Let let VB cord-282256-lqmixm7s 97 2 's -PRON- PRP cord-282256-lqmixm7s 97 3 be be VB cord-282256-lqmixm7s 97 4 optimistic optimistic JJ cord-282256-lqmixm7s 97 5 and and CC cord-282256-lqmixm7s 97 6 let let VB cord-282256-lqmixm7s 97 7 the the DT cord-282256-lqmixm7s 97 8 emerging emerge VBG cord-282256-lqmixm7s 97 9 data datum NNS cord-282256-lqmixm7s 97 10 be be VB cord-282256-lqmixm7s 97 11 our -PRON- PRP$ cord-282256-lqmixm7s 97 12 " " `` cord-282256-lqmixm7s 97 13 Ariadne Ariadne NNP cord-282256-lqmixm7s 97 14 's 's POS cord-282256-lqmixm7s 97 15 thread thread NN cord-282256-lqmixm7s 97 16 " " '' cord-282256-lqmixm7s 97 17 . . .