id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-298515-5n7hxhbg	Oarhe, Chinyere I.	Hyperoxia downregulates angiotensin-converting enzyme-2 in human fetal lung fibroblasts	2015-02-09		.txt	text/plain	5010	273	51	We report here the findings that ACE-2 protein and enzyme activity are severely decreased by hyperoxia in human fetal lung fibroblast cultures. Figure 6 shows that the treatment of hyperoxia followed by normoxic recovery significantly increased ADAM17/TACE immunoreactive protein by threefold in the IMR90 cells (P < 0.05). IMR90 cells were exposed to hyperoxic or normoxic gas as described in Figure 1 (with recovery), but in the presence or absence of the ADAM17/ TACE inhibitor TAPI-2. IMR90 cells were exposed to hyperoxic or normoxic gas as described in Figure 1 (with recovery), but in the presence or absence of the ADAM17/ TACE inhibitor TAPI-2. IMR90 cells were exposed to hyperoxic or normoxic gas as described in Figure 1 (with recovery), then were recovered for western blotting of ADAM17/TACE as described in Materials and Methods.	./cache/cord-298515-5n7hxhbg.txt	./txt/cord-298515-5n7hxhbg.txt