id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-282256-lqmixm7s	Tsioufis, Costas	The interplay of Hypertension, ACE-2 and SARS-CoV-2: Emerging data as the “Ariadne’s thread” for the “labyrinth” of COVID-19	2020-05-22		.txt	text/plain	1847	113	49	4 The only available meta-analysis from Wuhan of 46248 cases, supports that hypertension constitutes the most prevalent comorbidity in 17% of patients infected with the novel coronavirus. In Italy the most current analysis shows that of 69.1% of the deceased patients were hypertensives and 30% used angiotensin converting enzyme inhibitors (ACEIs) and 17% angiotensin receptor blockers (ARBs). 18 After adjustment for confounders there was no independent association for the use of ACEIs/ARBs with susceptibility for infection or worse clinical outcome in contrast to loop diuretics that were linked to enhanced risk. Hypertension, the renin-angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19 Risk of pneumonia associated with use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers: systematic review and meta-analysis Association of Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers with Mortality Among Patients With Hypertension Hospitalized With COVID-19	./cache/cord-282256-lqmixm7s.txt	./txt/cord-282256-lqmixm7s.txt