id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-253862-jl1zhg13	Khalaf, Khalil	SARS-CoV-2: Pathogenesis, and Advancements in Diagnostics and Treatment	2020-10-06		.txt	text/plain	14595	760	45	Although this novel virus is less severe than the first SARS-CoV outbreak, human-to-human transmission remains very high and the number of cases continues to rise exponentially in major urban areas, highlighting the urgent need to develop new containment, diagnostic, and treatment protocols. In the case of SARS-CoV-2, viral evasion of the innate immune system leads to an increase in cytokine production and late CD4+/CD8+ response, which then leads to pathogenic inflammation in patients with high viral loads. (ChiCTR2000029308), involving severe SARS-CoV-2 cases, compared lopinavir/ritonavir treatment with standard care alone, and they showed that the antivirals yielded no clinical benefits. In an open-label control study conducted by Cai et al., the antiviral activity of favipiravir + IFN-α was compared to that of lopinavir/ritonavir + IFN-α in patients with confirmed SARS-CoV-2 infection.	./cache/cord-253862-jl1zhg13.txt	./txt/cord-253862-jl1zhg13.txt